Journal articles, book chapters and other published papers

Cao, L., Chen, D.L., Lee, C.H., Chan, C.M., Chan, K.M., Vanittanakom, N., Tsang, D.N.C. and Yuen, K.Y. Detection of Specific Antibodies to an Antigenic Mannoprotein for Diagnosis of Penicilliosis Marneffei Penicilliosis. Journal of Clinical Microbiology, 1998, 36(10): 3028-3031.

Cao, L., Chan, K.M., Vanittanakom, N., Lee, C.H., Chan, C.M., Sirisanthana, T., Tsang, D.N.C. and Yuen, K.Y. Detection of Cell Wall Mannoprotein Mp1p in Culture Supernatants of Penicillium marneffei and in Sera of Penicilliosis Patients. Journal of Clinical Microbiology, 1999, 37(4): 981-986.

Chan, K.H., Luo, R.X., Luo, H.L., Chen, H.L., Ng, M.H., Seto, W.H. and Peiris, J.S.M. Development and evaluation of an Epstein-Barr virus (EBV) immunoglobulin M Enzyme-Linked Immunosorbent assay based on the 18-kilodalton matrix protein for diagnosis of primary EBV infection.. Journal of Clinical Microbiology, 1998, 36: 3359-3361.

Chan, K.L., Fan, S.T., Saing, H., Wei, W.I., Lo, C.M., Ng, I.O.L., Tsoi, N.S., Chan, J., Tso, W.K., Yuen, K.Y., Tam, P.K.H. and Wong, J. Paediatric liver transplantation at Queen Mary Hospital (abstract). Hong Kong Medical Journal Supplement, 1998, 4: 39.8.

Chim, J.C.S., Ho, P.L., Yuen, S.T. and Yuen, K.Y. Fungal endocarditis in bone marrow transplantation: case report and review of literature. Journal of Infection, 1998, 37: 287-304.

Chiu, S.S.S., Cheung, C.Y., Tse, C.Y.C. and Peiris, J.S.M. Early diagnosis of primary human herpesvirus 6 infection in childhood: Serology, polymerase chain reaction and virus load. Journal of Infectious Disease, 1998, 178: 1250-56.

Fitzner, K.A., Mcghee, S.M., Hedley, A.J. and Shortridge, K.F. Influenza surveillance in Hong Kong: results of a trial Physician Sentinel Programme. Hong Kong Medical Journal, 1999, 5: 87-94.

Ho, P.L., Chan, K.N., Ip, M.S.M., Lam, W.K., Ho, C.S., Yuen, K.Y. and Tsang, K.W.T. The Effect of Pseudomonas aeruginosa Infection on Clinical Parameters in Steady-State Bronchiectasis. Chest, 1998, 114: 1594-1598.

Ho, P.L., Que, T.L., Tsang, D.N.C., Ng, T.K., Chow, K.H. and Seto, W.H. Emergence of fluoroquinolone resistance among multiply resistant strains of Streptococcus pneumoniae in Hong Kong.. Antimicrobial Agents Chemotherapy, 1999, 43: 1310-1313.

Ip, M.S.M., Yuen, K.Y., Woo, P.C.Y., Luk, W.K., Tsang, K.W.T., Lam, W.K. and Liang, R.H.S. Pulmonary tuberculosis in bone marrow transplant recipients in Hong Kong. Respirology, 1998, 3 (suppl): A47.

Kumana, C.R., Ching, P.T.Y., Cheung, E., Kong, Y., Kou, M., Chan, C.K., Chu, K.M., Seto, W.H. and Lam, S.K. Antiulcer Drug Prescribing in Hospital successfully influenced by "Immediate Concurrent Feedback". Clinical Pharmacology & Therapeutics, St Louis, MI, Mosby Inc, 1998, 64: 569-74.

Lee, T., Yam, W.C., Tam, T.Y., Ho, B.S.W., Ng, M.H. and Broom, M.J. Occurrence Of Hepatitis A Virus In Green-Lipped Mussels (Perna Viridis). Water Research, 1999, 33(3): 885-889.

Lo, S.K.F., Woo, P.C.Y. and Yuen, K.Y. Hot spot mutations in morphological transforming region II (ORF 79) of cytomegalovirus strains causing disease in bone marrow transplant recipients.. Archives of Virology, 1999, 144: 601-612.

Luk, W.K., Wong, S.S.Y., Yuen, K.Y., Ho, P.L., Woo, P.C.Y., Lee, R.A. and Chau, P.Y. In-patient emergencies encountered by an infectious disease consultation service.. Clinical Infectious Disease, 1998, 26: 695-701.

Nicholls, J.M., Sommer, P., Kremmer, E., Ong, K.S., Fung, K.H.Y., Lee, J.M., Ng, M.H. and Grasser, F.A. A new lytic antibody, 7D6, detects Epstein-Barr virus dUTPase in nonkeratinizing undifferentiated nasopharyngeal carcinomas. Laboratory Inestigation, 1998, 78(8): 1031-1032.

Shortridge, K.F., Zhou, N.N., Guan, Y., Gao, P., Ito, T., Kawaoka, Y., Kodihalli, S., Krauss, S., Markwell, D.D., Murti, K.G., Norwood, M., Senne, D., Sims, L., Takada, A. and Webster, R.G. Characterization of avian H5N1 influenza viruses from poultry in Hong Kong. Virology, 1998, 252: 331-342.

Shortridge, K.F. Strictly for the birds?. Odyssey, 1999, 5: 8-15.

Shortridge, K.F. The 1918 'Spanish' flu: pearls from swine?. Nature Medicine, 1999, 5(4): 384-385.

Siu, L.K., Cheng, W.L., Ho, P.L., Ng, W.S., Chau, P.Y. and Lo, J.Y.C. Correlation of in vitro susceptibility testing results for amoxicillin-clavulanate and ampicillin-sulbactam using a panel of beta-lactqamase-producing Enterobacteriaceae.. APMIS, 1998, 106: 917-920.

Tsang, K.W.T., Ho, P.L., Chan, K.N., Ip, M.S.M., Lam, W.K., Ho, C.S., Yuen, K.Y., Ooi, G.C., Amitani, R. and Tanaka, E. A pilot study of low-dose erythromycin in bronchiectasis. European Respiratory Journal, 1999, 13: 361-364.

Tsang, K.W.T., Lam, W.K., Ho, P.L., Lam, B., Ho, J.C.M. and Yuen, K.Y. Sputum elastase levels correlate with disease activity paramenters in bronchiectasis. American Journal of Respiratory and Critical Care Medicine, 1999, 159 suppl 2: A307.

Tsang, K.W.T., Ho, P.L., Chan, K.N., Lam, W.K. and Ip, M.S.M. Oral levofloxacin in the treatment of bronchiectasis exacerbations. Acta Pharmacologica Sinica, 1998, 19 suppl: 85.

Tsang, K.W.T., Ho, P.L., Chan, K.N. and Lam, W.K. Inhaled fluticasone reduces sputum inflammation in chronic bronchial sepsis. Acta Pharmacologica Sinica, 1998, 19 suppl: 36.

Tsang, K.W.T., Ho, P.L., Ip, M.S.M., Lam, W.K., Yuen, K.Y., Amitani, R. and Tanaka, E. The effects of low dose erythromycin in bronchiectasis: a pilot study. European Respiratory Journal, 1999, 13: 361-364.

Tsang, K.W.T., Ip, M.S.M., Lam, W.K., Ho, P.L., Ho, C.S., Lam, B. and Yuen, K.Y. Predictors of sputum Pseudomonas aeruginosa in bronchiectasis. Respiratory, 1998, 3 (suppl): A37.

Wong, S.S.Y., Cao, L. and Yuen, K.Y. Management of Penicilliosis marneffei. The Journal of the American Medical Association Southeast Asia, 1998, 14: 7-9.

Wong, S.S.Y., Woo, P.C.Y., Luk, W.K. and Yuen, K.Y. Susceptibility testing of Clostridium difficile against metronidazole and vancomycin by disk diffusion and E-test.. Diagnostic Microbiology and Infectious Disease, 1999, 34: 1-6.

Yam, W.C., Tsang, D.N.C., Que, T.L., Peiris, J.S.M., Seto, W.H. and Yuen, K.Y. A Unique strain of Eescherichia coli O157:H7 That Produces Low Verocytotoxin Levels Not Detected by Use of a Commercial Enzyme Immunoassay Kit. Clinical Infectious Diseases, 1998, 27(Oct): 905-6.

Yam, W.C., Yuen, K.Y. and Seto, W.H. Direct Detection of Mycobacterium tuberculosis in Respiratory Specimens Using an Automated DNA Amplification Assay and a Single Tube Nested Polymerase Chain Reaction (PCR). Clinical Chemistry & Laboratory Medicine, 1998, 36(8): 597-599.

Yau, B.W.L., Wong, S.L., Chan, C.M. and Cao, L. Ultrastructural immunolabelling of Penicillium marneffei. Journal of Hong Kong Medical Technician Association, 1998, 7: 23-28.

Yuen, K.Y., Woo, P.C.Y., Hui, C.H., Luk, W.K., Chen, F.E., Lie, A.K.W. and Liang, R.H.S. Unique risk factors for bacteremia in bone marrow transplant recipients before and after engraftment. Bone Marrow Transplantation, 1998, 21: 1137-1143.

Yuen, M.F., Lau, W.C.S., Lau, Y.L., Wong, W.M., Cheng, V.C.C. and Lai, C.L. Mannose binding lectin gene mutations are associated with progression of liver disease in chronic hepatitis B infection. Hepatology, 1999, 29: 1248-1251.

Yuen, M.F., Lim, W.L., Cheng, V.C.C., Lam, S.K. and Lai, C.L. Twelve-Year Follow-up of a Prospective randomized trial of hepatitis B recombinant DNA yeast vaccine versus plasma-derived vaccine without booster doses in children. Hepatology, 1999, 29(3): 924-927.

Zhang, J., Chen, H.L., Zong, Y.S., Chan, K.H., Nicholls, J.M., Middeldorp, J.M., Sham, J.S.T., Griffin, B.E. and Ng, M.H. Epstein-Barr virus expression within keratinizing nasopharyngeal carcinoma. Journal of Medical Virology, 1998, 55: 227-233.

Zheng, B. Transcription units of E1a, E1b and pIX region of bovine adenovirus type 3. Journal of General Virology, 1999, 80: 1735-1742.

Zhou, N., Shortridge, K.F., Claas, E.C.J., Krauss, S. and Webster, R.G. Rapid evolution of H5N1 influenza viruses in chickens in Hong Kong. Journal of Virology, 1999, 73: 3366-3374.

Conference and working papers

Cao, L., Chen, D., Lee, C.H., Chan, C.M., Vanittanakom, N., Tsang, D.N.C. and Yuen, K.Y. Specific diagnostic antibody test for Penicilliosis marneffei.. Proceeding of the 4th China-Japan International Congress of Mycology, Zhuhai, China, 1998.

Cao, L., Chan, C.M., Lee, C.H., Wong, S.S.Y. and Yuen, K.Y. MP1 encodes an abundant and highly antigenic cell wall mannoprotein in pathogenic fungus Penicillium marneffei.. Proceedings of the 4th China-Japan International Congress of Mycology, Zhuhai, China, 1998.

Chan, K.H., Yan, M.K., Seto, W.H. and Peiris, J.S.M. Comparison of rapid diagnostic methods for influenza A.. National Virology Scientific Conference, Hong Kong, August 1998., 1998, Abstract p. 82.

Chan, K.H., Lo, S.K.F., Kwan, S.W., Lau, W.T., Tang, W.H., Yan, M.K., Seto, W.H., Peiris, J.S.M. and Ng, M.H. Use of ELISA with chimeric fusion proteins to detect IgM antibodies against Epstein Barr virus matrix protein for the diagnosis of primary EBV infection.. National Virology Scientific Conference, Hong Kong, August 1998, Abstract p.87.

Chan, W.M., Ho, P.L., Young, K., Siu, E., Seto, W.H. and Chan, J.C.K. The colonization patterns by resistant microorganisms in an adult ICU. Medical Research Conference. Hong Kong. 30-31 January, 1999.

Chua, D.T.T., Ng, M.H., Sham, J.S.T., Huang, J., Zheng, B., Kwong, D.L.W. and Choy, D.T.K. Adoptive cellular immunotherapy using Epstein-Barr virus specific cytotoxic T lymphocytes for nasopharyngeal carcinoma. Ninth International Congress on Anti-cancer Treatment, 1999, 209.

Ho, P.L., Yam, W.C., Que, T.L., Tsang, D.N.C., Ng, T.K. and Seto, W.H. Characterization of fluoroquinolone-resistant Streptococcus pneumoniae in Hong Kong. 39th Interscience Conference on Antimicrobial Agents and Chemotherapy. 26-29 September, 1999, San Francisco, California, U.S.A., 1999.

Ho, P.L., Tse, M.F., Wong, W.N. and Yuen, K.Y. Evaluation of a novel, inhibitor-potentiated disc-diffusion test for the detection of extended-spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae. 38th Interscience Conference on Antimicrobial Agents and Chemotherapy. 24-27 September, 1998. San Diego, California, USA, 1998.

Ho, P.L., Yuen, K.Y. and Seto, W.H. Emergence of multi-resistant ESBL-producing Enterobacteriaceae in Hong Kong. First International Congress. Hong Kong Academy of Medicine. 26-29 November, 1998.

Kwan, G.S.W., Lo, S.K.F., Lau, W.T., Tang, W.H., Yan, M.K., Chan, K.H., Peiris, J.S.M. and Seto, W.H. Monitoring for CMV infection in post transplant patients by pp65 antigenemia assay in peripheral blood leukocytes. National Virology Scientific Conference, Hong Kong, August 1998, Abstract p.84.

Leung, H.M., Yam, W.C., Peiris, J.S.M. and Ng, W.W.S. Isolation and Characterization of Verocytotoxigenic E. coli from animals and human sources in Hong Kong. Second International Symposium of the European Study Group on Enterohemorrhagic E. coli, April 1999, Brussels, Belgium., 1999.

Lo, S.K.F., Chan, K.H., Kwan, S.W., Lau, W.T., Tang, W.H., Yan, M.K., Peiris, J.S.M., Seto, W.H. and Yuen, K.Y. Evaluation of a in-house nested PCR for detection of CMV diseases in immunocompromised patients. National Virology Scientific Conference, Hong Kong, August 1998, Abstract p. 80.

Lo, S.K.F., Yuen, K.Y., Chan, K.H., Kwan, S.W., Lau, W.T., Tang, W.H., Yan, M.K., Peiris, J.S.M. and Seto, W.H. Evaluation of a in-house nested PCR for detection of CMV diseases in immunocompromised patients.. National Virology Scientific Conference, 1998.

Lui, S.L., Luk, W.K., Chan, T.M., Cheung, C.Y., Lai, K.N. and Peiris, J.S.M. Nosocomial outbreak of parvovirus B19 in a renal transplant unit.. 15th Annual Clinical Virology Symposium, Pan-American Society of Clinical Virology. May 1999., 1999, Abstract S24.

Lui, S.L., Luk, W.K., Chan, D.T.M., Peiris, J.S.M. and Lai, K.N. Nosocomial outbreak of parvovirus B19 infection in a renal transplant unit. Conference paper presented at the Annual Meeting of the American Society of Transplant Physicians, May 15-19, 1999, Chicago, USA.

Markwell, D.D., Shortridge, K.F., Peiris, J.S.M., Yam, W.C., Guan, Y. and Webster, R.G. Avian H9N2 influenza A virus in pigs from southern China - a novel event or pandemic warning?. XIth International Congress of Virology, Sydney, August, 1999, Abstract VP31.18.

Peiris, J.S.M. The H5N1 influenza outbreak in Hong Kong.. 3rd International Symposium on Viral and Chalmydial infections, March 1999, Tainan, Taiwan., 1999, Abstract p. 45-50.

Peiris, J.S.M., Cheung, C.Y., Luk, W.K. and Seto, W.H. Investigating nosocomial outbreaks of parvovirus B19 by molecular analysis.. XIth International Congress of Virology, Sydney, August, 1999., 1999, Abstract VP19.07.

Peiris, J.S.M., Yam, W.C., Chan, K.H., Ghose, P. and Shortridge, K.F. Detection and subtyping of influenza A H9N2 virus. XIth International Congress of Virology, Sydney, August, 1999, Abstract VP31.20.

Saing, H., Fan, S.T., Chan, K.L., Wei, W.I., Lo, C.M., Tsoi, N.S., Yuen, K.Y., Ng, I.O.L., Chau, M.T., Tso, W.K., Chan, J.K.F. and Wong, J. Liver transplantation in infants. 32nd Annual Meeting of Pacific Association of Pediatric Surgeons, 1999.

Shortridge, K.F. Pandemic influenza - A zoonosis. International Conference on Medical Virology, Beijing, 19-22 Oct. 1998 (Invited and Keynote Speaker), 1998.

Shortridge, K.F. Influenza H5N1: A Hong Kong perspective. Fifty Years of Influenza: A Challenge for the 21st Century, Geneva, 17-19 Feb. 1999 (Invited & Keynote Speaker), 1999.

Shortridge, K.F. The influenza H5N1 incident. International Conference on Emerging Diseases on the Pacific Rim: US-Japan Co-operative Medical Science Program, Bangkok, 2-4 March 1999 (Invited & Keynote Speaker), 1999.

Shortridge, K.F. Life after H5N1. Third Annual Scientific Meeting. The Hong Kong Society for Infectious Diseases, Hong Kong, 27 Mar. 1999.

Shortridge, K.F. Interspecies transmission of influenza viruses: H5N1 and the Hong Kong perspective. Symposium on Animal Influenza Viruses. University of Gent, Gent, Belgium, 16-18 May 1999.

Shortridge, K.F. H5N1 incident. Lecture tour in Japan speaking on the H5N1 incident - Invited & Keynote Speaker (a) Graduate School of Veterinary Science, Hokkaido University, Sapporo, Japan, 25 Feb. (b) Japanese Influenza Society, Annual Meeting, Niigata, 28 Feb. (c) School of Pharmaceutical Sciences, University of Shizuoka, 5 March, 1999.

Szeto, K.C., Lim, W.L. and Peiris, J.S.M. Early detection of ganciclovir resistant human cytomegalovirus by polymerase chain reaction and restriction analysis in immunosuppressed patients.. National Virology Scientific Conference, Hong Kong, August 1998., 1998, Abstract p. 81.

Tong, C.Y.W., Peiris, J.S.M., Williams, H., Cheung, C.Y. and Bakran, A. Clinical interaction of human herpesvirus 6 and 7 with human cytomegalovirus after renal transplantation.. 3rd International Conference on Human Herpesvirus 6, 7 and 8. May 1999, Florida, U.S.A., 1999, Abstract.

Tsang, K.W.T., Ho, P.L., Lam, W.K. and Ip, M.S.M. The efficacy of oral levofloxacin verus intravenous ceftazidime in empirical treatment of bronchiectasis exacebrations. Abstract Book of the 6th Western Pacific Congress of Chemotherapy and Infectious Diseases 98, 1998, 16.

Tsang, K.W.T., Lam, W.K., Chan, K.N., Ho, P.L., Ip, M.S.M., Ho, C.S., Lam, B. and Yuen, K.Y. Predictors of sputum microbiology in bronchiectasis. American Journal Respiratory Crit Care Med, 1998.

Tsang, K.W.T., Lam, W.K., Ho, P.L., Ip, M.S.M., Lam, B. and Yuen, K.Y. Predictors of sputum microbiology in chronic Chinese bronchiectasis.. Hong Kong Practitioner, 1998.

Yam, W.C., Chan, C.Y., Chow, K.H., Seto, W.H. and Yuen, K.Y. Epidemic Potential of Vibrio cholerae associated with its Virulence Factors and Survival Rate in Environmental Water. Conference in Colindale, 14-18 June 1999, London, UK, 1999.

Yam, W.C., Leung, E.T.Y., Seto, W.H. and Yuen, K.Y. Novel point mutation in inhA gene associated with Isoniazid (INH) Resistance in Mycobacterium tuberculosis. Regional Conference of International Union Against Tuberculosis and Lung Disease, 5-8 April, 1999, Hong Kong, 1999.

Yam, W.C., Leung, E., Seto, W.H. and Yuen, K.Y. Direct detection of point mutations in the gene encoding Catalase-peroxidase (katG), InhA protein (inhA), and enoyl acyl reductase (ahpC) of Isoniazid (INH) resistant Mycobacterium tuberculosis in clinical specimens.. 29th World Congress of the International Union Against Tuberculosis and Lung Disease, 1998.

Yam, W.C., Leung, E.T.Y., Seto, W.H. and Yuen, K.Y. Rapid Diagnosis of Isoniazid (INH) Resistant Mycobacterium tuberculosis in Clinical Specimens using PCR-RFLP analysis of Gene encoding Catalase-peroxidase (katG). Global Congress on Lung Health 29th World Conference of the International Union against Tuberculosis and Lung Disease, 23-26 November, 1998, Bangkok, Thailand, 1998.

Yuen, K.Y. Influenza infections : Nucleic acid amplification techniques in the diagnosis of tuberculosis. 20th Eastern Region Conference of the International Union Against Tuberculosis and Lung Disease, 1999.

Yuen, K.Y. Transplant-related sepsis. Hong Kong Academy of Medicine First International Congress, 1998.

Yuen, K.Y. Clinical and laboratory diagnosis of influenza A subtype H5N1.. Hong Kong Academy of Medicine First International Congress, 1998.

All other outputs

Cao, L., Jian, N. and Fleischmann, R.D. Dns Encoding Retinotic Acid Receptor Epsilon. Patents Of The Patent And Trademark Office Of The United States Of America For USD5869284, USA, 1999.

Cao, L. Vascular Endothelial Growth Factor-2 (VEGF-2) has the potential to revascularize the heart and limbs. Phase I/II trials of this gene-therapy drug, for the treatment of critical limb ischemia, were announced in late 1998 and Phase I/II trials in coronary artery disease began in the second quarter of 1999. The VEGF-2 trials are being conducted by Human Genome Sciences, Inc. and Vascular Genetics Inc., in which HGS has the ownership of the patents. Two US patents US5932540 & US5935820 on the discovery of a novel gene that is the foundation of two current Clinical Phase I/II Trials in the USA, USA, 1999.

Li, Y., Cao, L. and Rosen, C.A. Polynucleotides encoding human amine. Patents Of The Patent And Trademark Office Of The United States Of America For USD5798223, USD, 1998.

Li, Y., Cao, L. and Rosen, C.A. Human amine transporter. Patents of the Patent and Trademark Office of the United States of America for USD5859200, USA, 1999.

Ng, M.H. NPC and its Viral Connections. Hong Kong Museum of Medical Sciences Re: Public Lecture Series II - Recent Medical Advances, 1999.