RESEARCH AND SCHOLARSHIP 1999
RESEARCH OUTPUT
INSTITUTE OF MOLECULAR BIOLOGY

Academic Refereed

Journal articles, book chapters and other published papers

Burger, A.M., Fiebig, H.H., Kuettel, M.R., Lautenberger, J.A., Kung, H. and Rhim, J.S. Effect of oncogene expression on telomerase activation and telomere length in human edothelial, fibroblast and prostate epithelial cells. International Journal of Oncology, 1998, 13(5): 1043-1048.

Chen, H.-.D., Chen, C.-.L., Huang, S.-.W., Kung, H. and Chen, H.-.C. Characterization of latex components by capillary zone electrophoresis and N-terminal sequence. Journal of Biomedical Science, 1998, 5: 421-427.

Cho, K.S., Xiao, Y.M., So, K.F., Diao, Y.C. and Chung, S.K. Synergistic effect of optic and peripheral nerve grafts on sprouting of axon-like processes of axotomized retinal ganglion cells in adult hamsters. Neuroscience Letters, 1999, 265: 175-178.

Ho, H.T.B., Jenkins, N.A., Copeland, N.G., Gilbert, D.J., Winkles, J.A., Louie, H.W.Y., Lee, F.K., Chung, S.S.M. and Chung, S.K. Comparison of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes. European Journal of Biochemistry, 1999, 259: 726-730.

Jin, D., Spencer, F. and Jeang, K.-.T. Human T-cell leukemia virus type I oncoprotein Tax targets and human mitotic checkpoint protein MAD1. Cell, 1998, 93(1): 81-91.

Jin, D., Kozak, C.A., Pangilinan, F., Spencer, F., Green, E.D. and Jeang, K.-.T. Mitotic checkpoint locus MAD1L1 maps to human chromosome 7p22 and mouse chromosome 5. Genomics, 1999, 55(3): 363-364.

Jin, D. and Jeang, K.-.T. Isolation of full-length cDNA and chromosomal localization of human NF-ƒÛB modulator NEMO to Xq28. Journal of Biomedical Science, 1999, 6(2): 115-120.

Jin, D., Giordano, V., Kibler, K.V., Nakano, H. and Jeang, K.-.T. Role of adapter function in oncoprotein-mediated activation of NF-ƒÛB: Human T-cell leukemia virus type I Tax interacts directly with IƒÛB kinase ƒ×. Journal of Biological Chemistry, 1999, 274(25): 17402-17405.

Jones, T.L., Kim, J., Xu, R.-.H., Chong, L.D., Kung, H. and Daar, I.O. Loss of cell adhesion in Xenopus laevis embryos mediated by the cytoplasmic domain of XLerk, and Eph ligand. Proceedings of National Academy of Sciences USA, 1998, 95: 576-581.

Kamata, T., Subleski, M., Copeland, T., Kung, H. and Xu, R.H. Xenopus CRMP-2 is an early response gene to neural induction. Molecular Brain Research, 1998, 57: 201-210.

Kamata, T., Subleski, M., Hara, Y., Yuhki, N., Kung, H., Copeland, N.G., Jenkins, N.A., Yoshimura, T., Modi, W. and Copeland, T.D. Isolation and characterization of a neural specific protein (NSP60) gene homologous to C. elegans unc-33 controlling axonal outgrowth and guidance. Molecular Brain Research, 1998, 54: 219-236.

Kim, J., Ault, K.T., Chen, H.D., Xu, R.H., Roh, D.H., Lin, M.C., Park, M. and Kung, H. Transcriptional regulation of BMP-4 in the Xenopus embryo: analysis of genomic BMP-4 and its promoter. Biochemical and Biophysical Research Communications, 1998, 250: 516-530.

Kim, J., Lin, J.-.J., Xu, R.-.H. and Kung, H. Mesoderm induction by Heterodimer AP-1 (c-Jun and c-Fos) and its involvement in mesoderm formation through Xbra/eFGF autocatalytic loop during the early development of Xenopus embryos. Journal of Biological Chemistry, 1998, 273: 1542-1550.

Krishnan, R., Goodman, B., Jin, D., Jeang, K.-.T., Collins, C., Stetten, G. and Spencer, F. Map location and gene structure of the Homo sapiens mitotic arrest deficient 2 (MAD2L1) gene at 4q27. Genomics, 1998, 49(3): 475-478.

Lee, A.Y.W. and Chung, S.S.M. Contributions of polyol pathway to oxidative stress in diabetic cataract. Federation of American Societies for Experimental Biology Journal, 1999, 13: 23-30.

Lee-Huang, S., Huang, P., Sun, Y., Huang, P.L., Kung, H., Blithe, D.L. and Chen, H.C. Lysozyme and ribonucleases as anti-HIV components in beta-core preparation of hCG. Proceedings of National Academy of Sciences USA, 1999, 96: 2678-2681.

Lin, K.-.T., Xue, J.-.Y., Lin, M.C., Spokas, E.G., Sun, F.F. and Wong, P.Y.-.K. Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease. American Journal of Physisology, 1998, 274: C855-860.

Smith, M.R., Court, D.W., Kim, H.-.K., Park, J.-.B., Rhee, S.G., Rhim, J.S. and Kung, H. Overexpression of PLCƒ× in NIH 3T3 cells promotes transformation and tumorigenecity. Carcinogenesis, 1998, 19: 177-185.

Spector, A., Kuszak, J.R., Ma, W., Wang, R.-.R., Ho, Y.-.S. and Yang, Y. The effect of photochemical stress upon the lenses of normal and glutathione peroxidase-1 knockout mice. Experimental Eye Research, 1998, 67: 457-471.

Spector, A., Ho, Y.-.S., Wang, R.-.R., Ma, W., Yang, Y. and Li, W.-.C. Evaluation of the antiperoxide defense system of the lens utilizing GSH peroxidase transgenics and knockouts. In Montagnier, L., R. Oliver and C. Pasquier, eds. Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases. pp. 507-515. Marcel Dekker, Inc., New York, 1998.

Tsai, W.P., Kung, H. and Nara, P. The presence and absence of histocompatibility antigens in HIV-1 produced by autologous blood-derived macrophages and peripheral blood lymphoblasts. AIDS Research and Human Retroviruses, 1999, 15: 33-41.

Xu, R.H., Ault, K.T., Kim, J., Park, M.J., Hwang, Y.S., Peng, Y., Sredni, D. and Kung, H. Opposite effects of FGF and BMP-4 on embryonic blood formation: Roles of PV. 1 and GATA. 2. Developmental Biology, 1999, 208: 352-361.

Xu, R.H., Lechleider, R.J., Shih, H.M., Hao, C.F., Sredni, D., Roberts, A.B. and Kung, H. Functional analysis of human smad 1: role of the amino-terminal domain. Biochemical and Biophysical Research Communications, 1999, 258(2): 366-373.

Yang, Y., Spector, A., Ma, W., Wang, R.-.R., Larsen, K. and Kleiman, N.J. The effect of catalase amplification on immortal lens epithelial cell lines. Experimental Eye Research, 1998, 67: 647-656.

Conference and working papers

Chan, S.K., Chung, S.S.M. and Chung, S.K. Regulation of preproendothelin-1gene expression during embryonic development in transgenic mice. Experimental Biology '99 Meeting, organized by the Federation of American Societies for Experimental Biology (FASEB), Washington DC, USA, April 17-21, 1999.

Devalck, D., Jin, D., Heyninck, K., Van De Craen, M., Contreras, R., Fiers, W., Jeang, K.-.T. and Beyaert, R. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene, 1999, 18(29): 4182-4190.

Ho, M.C.Y., Lo, A.C.Y., Yu, A.C.H. and Chung, S.K. Possible roles of endothelin-1 in astrocytes during hypoxic/ischemic brain injury. Experimental Biology '99 Meeting, organized by the Federation of American Societies for Experimental Biology (FASEB), Washington DC, USA, April 17-21, 1999, 13: Abstract 412.4.

Hukku, B., Cher, M., Peehl, D.M., Kung, H. and Rhim, J.S. Stepwise genetic changes associated with the progression of nontumorigenic HPV-18 immortalized human prostate cancer-derived cell line to a malignant phenotype. AACR Annual Meeting, Philadelphia, PA, USA, April 10-14, 1999, Abstract: p. 17.

Jin, D. HTLV-I oncogenesis and mitotic checkpoint (oral presentation). American Society for Virology 17th Annual Meeting, Vancouver, July, 1998.

Jin, D. and Jeang, K.-.T. Peroxiredoxins in cell signaling and HIV-1 infection. In Sen, C.K., Siers, H. and Baeuerle P.A. (eds.): Antioxidant and Redox Regulaiton of Genes. Academic Press, San Diego, USA, 1999, 381-407.

Jin, D. HTLV-I Tax and spindle assembly checkpoint (oral presentation at a plenary session). Cold Spring Harbor Laboratory Retroviruses Meeting, New York, USA, May, 1998.

Jin, D. HTLV-I oncoprotein Tax targets a mitotic checkpoint (oral presentation). International Symposium for Biology Sciences, Shanghai, China, December, 1998.

Kung, H. DNA vaccines. ¡m¤Þ ¶i ®ü ¥~ ·s ¬ì §Þ -- ¹A ·~ ¥Í ª« §Þ ³N ¬ã °Q ·|¡n Taipei, National Pingtung University of Science and Technology, 1999, Abstract: p. 13.

Kung, H. Biotechnology and cancer research. ¡m¤Þ ¶i ®ü ¥~ ·s ¬ì §Þ --¹A ·~ ¥Í ª« §Þ ³N ¬ã °Q ·|¡n Taipei, National Pingtung University of Science and Technology, 1999, Abstract: p. 14.

Lee, W.Y., Ko, C.B. and Chung, S.S.M. Regulation and signalling pathway of aldose reductase, betaine transporter, myo-inositol transporter genes expression by hyperosmolality. Experimental Biology '99 Meeting, organized by the Federation of American Societies for Experimental Biology (FASEB), Washington DC, USA, April 17-21, 1999.

Liang, X., Chung, S.K., Yeung, C.Y. and Cheung, P.T. Bilirubin Upregulates Interleukin-6 Expression in Endothelia Cells. Asia Pacific Symposium on Neural Regeneration, 3-4 December 1998, Hong Kong, The University of Hong Kong.

Lin, M.C. and Kung, H. Enchanced expression of intestinal microsomal triglyceride transfer protein in zucker diabetic fatty rats, the role of oleate and growth hormones. Annual Physiology Meeting, and abstract in Biological Signals and Receptors, May, 1999, 8: 208.

Lin, M.C., Peng, Y. and Kung, H. Alcohol-induced brain injury: A Xenopus laevis model of fetal alcohol syndrome. Annual Symposium of Horizons in Developmental Toxicology and Developmental Biology, Univ. of Wisconsin-Madson, USA, June, 1999.

Ma, W., Yang, Y., Wang, R.-.R. and Spector, A. Characteristics of catalase transgenics controlled by a lens specific promoter. ARVO Annual Meeting, Fort Lauderdale, FL, USA, 1999.

Song, Z., Chung, S.S.M., Chan, Y.S. and Chung, S.K. Effects of Schwann cell-specific over-expression of aldose reductase on diabetic and galactosemic neuropathy. American Diabetes Association, 59th Scientific Sessions, San Diego, CA, USA, June 19-22, 1999.

Spector, A., Yang, Y., Ma, W., Wang, R.-.R. and Kuszak, J.R. Oxidative stress and cataract. Abstract, XIII International Congress for Eye Research, Paris, France, 1998.

Yang, H., Yip, H.K.F. and Chung, S.K. The expression patterns of p75 and zebrin II mrnas in the developing rat cerebellum. Neuroscience Letters, 1998, 49: S18.

Yang, Y., Ma, W., Kelz, M.B., Chen, J., Kuszak, J.R. and Spector, A. Overexpression of delta-FosB causes cataract. ARVO Annual Meeting, Fort Lauderdale, FL, USA, 1999.