DEPARTMENT OF SURGERY



Researcher : Au DKK
Project Title:The development of a Cantonese tone trainer for use with speech and hearing impaired people
Investigator(s):Mr. Au D.K.K. , Dr. So L.K.H.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1992
Abstract:
To develop a prototype computer programmed Cantonese tone speech viewer.


Project Title:Otoacoustic emission measurement (OAE) in patient receiving streptomycin injection
Investigator(s):Mr. Au D.K.K. , Prof. Wei W.I.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1994
Abstract:
To study the value of OAE as more sensitive screening test than pure tone audiogram in identifying patient who is more vulnerable to the ototoxic effect of streptomycin. So that modification of treatment regimen can be implemented before irreversible damage occur.


List of Research Outputs

Au D.K.K., Hui Y., Wong Y.K., Comparison of the results of two different implant systems using continuous interleaved sampler speech processing strategy, Advances in Otorhinolaryngology. 2000, 57: 430-434.
Cheng W., Au D.K.K., Knowles C.H., Tam P.K.H., Anand P., Hirschsprung's disease: a more generalised neuropathy?, Journal of Pediatric Surgery. 2001, 36 (2): 296-300.
Ho W.K., Hui Y., Wei W.I., Au D.K.K., Correlation of pure tone audiogram result and hearing benefit of tympanoplasty for chronic suppurative otitis media, Annals of Otology, Rhinology and Laryngology. 2000, 109: 381-384.
Wei W.I., Wong R., Hui Y., Au D.K.K., Wong Y.K., Ho W.K., Tsang A., Kung P., Chung E., Chinese tonal language rehabilitation following cochlear implantation in children, Acta Oto-laryngologica (Stockh). 2000, 120: 218-221.
Wong Y.K., Hui Y., Au D.K.K., Wei W.I., Economic evaluation of cochlear implantation, Advances in Otorhinolaryngology. 2000, 57: 377-381.


Researcher : Chan KL
List of Research Outputs

Chan G.C.F., Ha S.Y., Lau Y.L., Chan K.L., Tam P.K.H., Cheung A.N.Y., Letter to the Editor: Linitis plastica presenting as malignant ascites, Medical and Pediatric Oncology. 2001, 34: 1-2.
Chan G.C.F., Chan K.L., Kwong D.L.W., Chiang A.K.S., Lee T.L., Ha S.Y., Tam P.K.H., Lau Y.L., Malignant tumours in the head and neck region in childhood: good outcome with current therapeutic approach, 7th Hong Kong International Cancer Congress, Hong Kong, 7-9 December 2000.
Chan K.L., Zhou H., Ng D.K.K., Tam P.K.H., A prospective study of a one-week non- bismuth quadruple therapy for childhood Helicobacter pylori infection, Journal of Pediatric Surgery. 2001, 36: 1008-1011.
Chan K.L., Co-ordinator, Liver Transplantation Team (1993 - present), Queen Mary Hospital, 2001.
Chan K.L., Hui C., Wo J.Y.H., Tipoe G.L., Fung P.C.W., Tam P.K.H., Developmental profile of manganese and copper zinc superoxide dismutases in rat intestines and its implications in ischaemia and reperfusion injury, 34th Annual Meeting of Pacific Assoication of Pediatric Surgeons, Kyoto, Japan, April 4-8, 2001.
Chan K.L., Guo W.H., Chan K.W., Tam P.K.H., FR167653 ameliorates intestinal allograft ischemia injury, Transplantation Proceedings. 2000, 32: 1643-1644.
Chan K.L., Tang M.H.Y., Sin S.Y., Wong H.S., Tang R., Tam P.K.H., In utero pleuro-amniotic shunting for bilateral fetal chylothorax and hydrop fetalis, XVII Congress of Asian Association of Pediatric Surgeons. Fukuoka, Japan, November 6-9, 2000.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Liver transplantation is not contraindicated in infancy, Transplantation Proceedings. 2000, 32(7): 2142-2143.
Chan K.L., Tam P.K.H., Meconium ileus-like conditions in Hong Kong Chinese neonates, XVII Congress of Asian Association of Pediatric Surgeons, Fukuoka, Japan, November 6-9, 2000.
Chan K.L., Member, Clinical Audit Committee (May 1997 - present), Queen Mary Hospital, 2001.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Post liver transplantation stenosis of biliary-enteric anastomoses in infancy: diagnosis and treatment, Transplantation Proceedings. 2000, 32(7): 2233-2234.
Chan K.L., Hui C., Wo J.Y.H., Tipoe G.L., Fung P.C.W., Tam P.K.H., Revisiting ischaemia and reperfusion injury as a possible cause for necrotising enterocolitis, 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, April 4-8, 2001.
Chan K.L., Guo W.H., Tam P.K.H., Technical refinements for successful small bowel transplantation in pig, Transplantation Proceedings. 2000, 32: 2488-2489.
Chan K.L., Zhou H., Tam P.K.H., Helicobacter pylori negative childhood duodenal ulcers: a prospective study, XVII Congress of Asian Association of Pediatric Surgeons, Fukuoka, Japan, November 6-9, 2000.
Chan S.Y., Chan K.L., Pathogenesis of neonatal necrotizing enterocolitis, Annals of the College of Surgeons of Hong Kong. 2001, 5: 52-54.
Cheng W., Zhou H., Chan K.L., Tam P.K.H., Management of acute appendicitis: specialist-based versus trainee-based service, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Guo W.H., Chan K.L., Fung P.C.W., Chan K.W., Tam P.K.H., Nitric oxide protects segmental intestinal grafts from ischaemia and reperfusion I/R injury, Transplantation Proceedings. 2000, 32: 1297-1298.
Guo W.H., Tian L., Yuen Z.W., Chan K.L., Wo J.Y.H., Nicholls G., Dallman M., Tam P.K.H., Recipient FK506 pretreatment regimens in rat small bowel transplantation: allograft survival, function, and systemic infection, Journal of Pediatric Surgery. 2000, 35: 1600-1605.
Guo W.H., Tian L., Chan K.L., Dallman M., Tam P.K.H., Role of CD4+ and CD8+ T cells in early and late acute rejection of small bowel allograft, Journal of Pediatric Surgery. 2001, 36(2): 352-356.
Guo W.H., Tian L., Chan K.L., Tam P.K.H., Role of activated helper and cytotoxic T cells in early and late rejection of small bowel allograft, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Khong P.L., Peh W.C.G., Lam C.H.L., Chan K.L., Cheng W., Lam W.W.M., Saing H., Tam P.K.H., Leong Fung L.L.Y., Low L.C.K., Ultrasound-guided hydrostatic reduction of childhood intussusception: technique and demonstration, RadioGraphics. 2000, 20(5): E1.
Khong P.L., Peh W.C., Lam C.H., Chan K.L., Cheng W., Lam W.W., Ai V.H., Saing H., Tam P.K., Leong L.L., Low L.C.K., Ultrasound-guided hydrostatic reduction of childhood intussusception: technique and demonstration, Radiographics. 2000, 20(5): E1-e1.
Lam W.W.M., Tam P.K.H., Chan F.L., Chan K.L., Cheng W., Esophageal atresia and tracheal stenosis: use of three-dimensional CT and virtual bronchoscopy in neonates, infants and children, American Journal of Roentgenology. 2000, 174: 1009-1012.
Lam W.W.M., Tam P.K.H., Ai V.H.G., Chan K.L., Chan F.L., Leong L., Using gadolinium-infusion MR venography to show the impalable testis in pediatric patients, American Journal of Roentgenology. 2001, 176: 1221-1226.
Saing H., Fan S.T., Wei W.I., Chan K.L., Lo C.M., Mya G.H., Tsoi N.S., Yuen K.Y., Ng I.L.O., Chau M.T., Tso W.K., Chan J.F.K., Wong J., Pediatric liver transplantation: the Hong Kong experience, 6th Congress of the Cambodian Surgical Society, Cambodia, October 25-26, 2000.
Saing H., Fan S.T., Chan K.L., Wei W.I., Lo C.M., Mya G.H., Wong J., Portoenterostomy complimented by liver transplantation for biliary atresia: the Queen Mary Hospital, Hong Kong experience, 6th Congress of the Cambodian Surgical Society, October 25-26, 2000.
Siow Y.L., Chan K.L., Tam P.K.H., Stress-activated protein (SAP) kinase: a new marker for intestinal ischemia, Transplantation Proceedings. 2000, 32: 1302-1303.
Sun N., Chan K.L., OK-432 (Picibanil) therapy for lymphangioma: collective experience in the literature, Annals of the College of Suregons of Hong Kong. 2001, 5: 55-58.
Sun N., Cheung T.T., Kwong P.L., Chan K.L., Tam P.K.H., Varicocele: laparoscopic clipping and colour doppler ultrasound follow-up, 34th Annual Meeting of Pacific Association of Pediatric Surgeons , Kyoto, Japan, April 4-8, 2001.
Tam P.K.H., Chan K.L., Laparoscopic anorectal pullthrough for high imperforate anus-technical variations., 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, 4-8 April, 2001.
Zhao H.T., Chan K.L., Chen Q.M., Guo W.H., To J., Tam P.K.H., Comparative study of glutathione-S-transferase isoenzyme, endotoxin and tumour necrosis factor as markers for intestinal ischaemia, 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, 4-8 April, 2001.
Zhou H., Chan K.L., Chu K.M., Tam P.K.H., Intrafamilial spread of Helicobacter pylori: a prospective study using urea breath test, Journal of Pediatric Surgery. 2000, 35: 1672-1675.


Researcher : Chen BLS
List of Research Outputs

Sham M.H., Lui V.C.H., Chen B.L.S., Fu M., Tam P.K.H., Novel mutations of SOX10 suggest a dominant negative role in Waardenburg-Shah syndrome, Journal of Medical Genetics. 2001, 38(9): E30.
Sham M.H., Lui V.C.H., Fu M., Chen B.L.S., Tam P.K.H., SOX10 is abnormally expressed in aganglionic bowel of Hirschsprung's disease infants, Gut. 2001, 49(2): 220-226.


Researcher : Chen Y
List of Research Outputs

Chen Y., Lui V.C.H., Sham M.H., Tam P.K.H., Deficiency of novel inhibitory neurotransmitter carbon monoxide in aganglionic bowel of Hirschsprung's disease., In: The XLVIII Annual International Conference of the British Association of Paediatric Surgeons, London, U.K., 2001.


Researcher : Cheng SWK
Project Title:A study of the relationship of serum lipoprotein (a) and the progression of atherosclerotic peripheral vascular disease
Investigator(s):Prof. Cheng S.W.K. , Dr. Ting A.C.W., Prof. Wong J.
Department:Surgery
Source(s) of Funding:Hong Kong Research Grants Council Competitive Earmarked Research Grants
Start Date:January 1996
Completion Date:December 2000
Abstract:
To determine the rate of progression of atherosclerotic peripheral vascular disease (PVD) in the Chinese population in relationship to demographic and biochemical risk factors; to test the hypothesis that an elevated level of serum lipoprotein (a) is associated with more rapid progression of PVD; to determine whether treatment of elevated lipoprotein (a) with combination of niacin and neomycin will result in a reduction in the progression of atherosclerotic PVD.


Project Title:Cytomegalovirus (CMV) and Chlamydia pneumoniae (CP) infections in patients with atherosclerotic occlusive disease of the lower extremities
Investigator(s):Prof. Cheng S.W.K. , Dr. Ting A.C.W.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1999
Abstract:
To investigate the prevalence of Cytomegalovirus (CMV) and Chlamydia pneumoniae (CP) infection in patients with atherosclerotic occlusive disease of the lower extremities; to correlate CMV and CP antibody titres with the severity and progression of atherosclerotic occlusive disease of the lower extremities.


Project Title:Carotid artery plaque characterization using ultrasonic digital imaging and its relationship to the risk of stroke
Investigator(s):Prof. Cheng S.W.K. , Dr. Ting A.C.W.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:February 2001
Abstract:
To collect quantitatively, by computer digital processing, carotid plaque morphology in patients with atherosclerotic disease; to test the hypothesis that stroke rate is associated with aggressive plaque morphology; to identify a high risk subgroup based on plaque characteristics.


List of Research Outputs

Cheng S.W.K., Course Director, Advanced Trauma Life Support Course, American College of Surgeons (Hong Kong Chapter), 2001.
Cheng S.W.K., Course Instructor, Advanced Trauma Life Support Course (1997 - present), American College of Surgeons (Hong Kong Chapter), 2001.
Cheng S.W.K., Ting A.C.W., Wong J., Endovascular stenting of superficial femoral artery stenosis and occlusions: results and risk factor analysis, Cardiovascular Surgery. 2001, 9(2): 133-140.
Cheng S.W.K., Honorary Consultant in Vascular Surgery, Department of Surgery (March 1999 - present), Tung Wah Hospital, 2001.
Cheng S.W.K., Honorary Consultant, Department of Surgery (July 1997 - present), Queen Mary Hospital, 2001.
Cheng S.W.K., Regional Faculty, Advanced Trauma Life Support Course (1997 - present), American College of Surgeons (Hong Kong Chapter), 2001.
Cheng S.W.K., Wong J., Vascular surgery in Hong Kong: a review of two decades of development, Asian Journal of Surgery. 2000, 3: 199-202.
Lau H., Cheng S.W.K., Axillofemoral bypass for limb salvage, Annals of the College of Surgeons of Hong Kong. 2000, 4: 149-153.
Lau H., Cheng S.W.K., Lam K.Y., Carotid artery aneurysm secondary to cystic medial necrosis, Journal of Royal College of Surgeons of Edinburgh. 2001, 46: 173-175.
Lau H., Cheng S.W.K., Is the preferential use of ePTFE grafts in femorofemoral bypass justified?, Annals of Vascular Surgery. 2001, 15(3): 383-387.
Lau H., Cheng S.W.K., Long-term outcome of aortofemoral bypass for aortoiliac occlusive disease, Annals of Academy of Medicine, Singapore. 2000, 29: 434-438.
Lau H., Cheng S.W.K., Long-term prognosis of femoropopliteal bypass: an analysis of 349 consecutive revascularizations, The Australian and New Zealand Journal of Surgery. 2001, 71: 335-340.
Ting A.C.W., Cheng S.W.K., Wong Wu L.H., Cheung G.C.Y., Changes in venous hemodynamics after superficial vein surgery for mixed superficial and deep venous insufficiency, World Journal of Surgery. 2001, 25: 122-125.


Researcher : Cheng W
List of Research Outputs

Cheng W., Development of duodenum and duodenal atresia, Thesis, Master of Surgery, The University of Hong Kong. 2000.
Khong P.L., Peh W.C.G., Lam C.H.L., Chan K.L., Cheng W., Lam W.W.M., Saing H., Tam P.K.H., Leong Fung L.L.Y., Low L.C.K., Ultrasound-guided hydrostatic reduction of childhood intussusception: technique and demonstration, RadioGraphics. 2000, 20(5): E1.
Lam W.W.M., Tam P.K.H., Chan F.L., Chan K.L., Cheng W., Esophageal atresia and tracheal stenosis: use of three-dimensional CT and virtual bronchoscopy in neonates, infants and children, American Journal of Roentgenology. 2000, 174: 1009-1012.


Researcher : Cheung DLC
List of Research Outputs

Au W.K., Cheung D.L.C., Photodynamic therapy for lung cancer, Departmental Journal Review. 2000.
Suen W.S., Cheung D.L.C., The strategies of prevention of venous graft stenosis, Departmental Journal Review. 2001.
Yong J.L., Cheung D.L.C., Cognitive dysfunction after cardiopulmonary bypass, Departmental Journal Review. 2001.


Researcher : Cheung ST
List of Research Outputs

Chen X., Cheung S.T., Barry C., Fan S.T., Lai K.M., Ji F.J., Praprong W., Botstein D., Brown P., So S., Genome-wide study of human hepatocellular carcinoma with 23K cDNA microarray, The 51st Annual Meeting and Postgraduate Courses of the American Association for the Study of Liver Diseases. Dallas, Texas, USA. Hepatology, 2000.
Cheung S.T., Chen X., Fan S.T., So S., Ng I.O., Brown P., Genome-wide expression profiling of hepatocellular carcinoma by cDNA microarray technology, 7th Hong Kong International Cancer Congress. 2000.
Cheung S.T., Chen X., Fan S.T., So S., Ng I.O.L., Brown P., Molecular characterization of hepatocellular carcinoma by cDNA microarray, Proceedings of the American Association for Cancer Research. 2001, 42: 3285.
Cheung S.T., Chen X., Fan S.T., So S., Ng I.O., Brown P., Molecular characterization of hepatocellular carcinoma by cDNA microarray, The 92nd Annual Meeting of the American Association for Cancer Research. New Orleans, Los Angeles, USA. 2001.
Lee S.P., Chan A.T., Cheung S.T., Thomas W.A., Croomcarter D., Dawson C.W., Tsai C.H., Leung S.F., Johnson P.J., Huang D.P., CTL control of EBV in nasopharygeal carcinoma (NPC): EBV-specific CTL resopnses in the blood and tumors of NPC patients and the antigen-processing function of the tumor cells, Journal of Immunology. 2000, 165(1): 573-582.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis., Annas ofl Surgery. 2001, 233(2): 276-281.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis, Annals of Surgery. 2001, 233: 276-281.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 373:A944.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.


Researcher : Chow LWC
Project Title:A review of clinical experience in the diagnosis and management of gastroduodenal smooth muscle tumours
Investigator(s):Dr. Chow L.W.C. , Dr. Chow W.M., Dr. Chu K.W., Dr. Ho J.C.Y., Dr. Mok F.P.T., Dr. Yuen S.T.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:May 1990
Abstract:
To review more than 100 patients who suffered from gastroduodenal smooth muscle tumours from 1979 to present, and to study the course of the disease and the response to surgical treatment.


Project Title:A review of clinical experience in the diagnosis and management of gastroduodenal smooth muscle tumours
Investigator(s):Dr. Chow L.W.C. , Dr. Chow W.M., Dr. Chu K.W., Dr. Ho J.C.Y., Dr. Mok F.P.T., Dr. Yuen S.T.
Department:Surgery
Source(s) of Funding:Wu Chung Medical Research Fund
Start Date:May 1990
Abstract:
To review more than 100 patients who suffered from gastroduodenal smooth muscle tumours from 1979 to present, and to study the course of the disease and the response to surgical treatment.


Project Title:In-vitro chemosensitivity testing for breast cancer using histoculture drug response assay (HDRA)
Investigator(s):Dr. Chow L.W.C.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1996
Abstract:
To optimize the chemotherapy regimen for individual breast cancer patients to produce an improved tumour response and patients survival.


Project Title:The prediction of persistent drainage, seroma formation and wound necrosis after mastectomy
Investigator(s):Dr. Chow L.W.C.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1998
Abstract:
To determine whether matrix metalloproteinases account for the delay in wound healing and persistent collection of fluid after mastectomy and axillary dissection.


Project Title:Role of selectin in the postoperative recovery after mastectomy for breast cancer
Investigator(s):Dr. Chow L.W.C.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1999
Abstract:
To determine whether selectin is responsible for the acute inflammatory response and postoperative recovery after surgical trauma from mastectomy for breast cancer.


List of Research Outputs

Chan S.C., Chow L.W.C., Results of treating patients with advanced metastatic breast cancer by capecitabine as a single agent, 7th Hong Kong International Cancer Congress, Hong Kong, December 2000.
Chan S.C., Chow L.W.C., Treatment of metastatic breast cancer by capecitabine as a single agent, The 3rd Biennial Meeting of the Asian Breast Cancer Society, Seoul, Korea, June 2001.
Cheung T.T., Chow L.W.C., Conserving surgery for invasive breast cancer, Departmental Journal Review. 2000.
Choi H.K., Chow L.W.C., Goh L.C., Tsui S.L., Lee F.C.W., The impact of postoperative nausea and vomiting on the practice of day surgery for Chinese women with breast diseases, Ambulatory Surgery. 2001, 9: 29-32.
Chow L.W.C., Yuen K.Y., Woo P.C.Y., Wei W.I., Clarithromycin attenuates mastectomy - induced acute inflammatory response, Clinical Diagnostic Laboratory Immunology. 2000, 7: 925-931.
Chow L.W.C., Ho P., Hormonal receptors determination of 1052 Chinese breast cancer, Journal of Surgical Oncology. 2000, 75: 172-175.
Chow L.W.C., Loo T.Y., Matrix metalloproteinases 1 and 3 are responsible for breast cancer invasion inhistoculture, Nippon Roche Cancer Conference on Matrix Metalloproteinases, Tokyo, Japan, November 2000.
Chow L.W.C., Day W., Ng K.C.K., Neoadjuvant chemotherapy for Chinese women with locally advanced breast cancer, The American Surgeon. 2001, 67(5): 412-416.
Ho L.W.C., Wong K.P., Chan J.H.M., Chow L.W.C., Leung E.Y.F., Leon L., MR appearance of metastatic melanotic melanoma in the breast, Clinical Radiology. 2000, 572-573.
Hu X., Chow L.W.C., Detection of circulating breast cancer cells with multiple-marker RT-PCR assay, Anticancer Research. 2001, 21: 421-424.
Hu X., Chow L.W.C., Fine needle aspiration may shed breast cells into peripheral blood as determined by RT-PCR, Oncology. 2000, 59(3): 217-222.
Hu X., Chow L.W.C., Review - Detection of circulating breast cancer cells by reverse transcriptase-polymerase chain reaction (RT-PCR), European Journal of Surgical Oncology. 2000, 26: 530-535.
Hu X.C., Chow L.W.C., Hypermethylated promoter of p16 gene as a promising blood marker in Chinese patients with breast cancer, 7th Hong Kong International Cancer Congress, Hong Kong, December 2000.
Kwan E., Chow L.W.C., Prognostic factors in metastatic breast cancer, Departmental Journal Review. 2001.
Lam T.P., Irwin M.G., Chow L.W.C., Chan Y.L., Early introduction of clinical skills teaching in a medical curriculum-factors affecting students' learning, The Scholarship of Teaching and Learning. Hong Kong Academy of Medicine. June. Hong Kong, 2001.
Lam T.P., Irwin M.G., Chow L.W.C., Chan Y.L., The use of focus group interviews in Asian medical education evaluative research, Medical Education. U.K., 2001, 35(5): 510-513.
Lam T.P., Irwin M.G., Chow L.W.C., Chan Y.L., The use of focus group interviews in Asian medical education evaluative research, The Scholarship of Teaching and Learning. Hong Kong Academy of Medicine. Hong Kong, 2001.
Ng K.K.C., Fung S.Y., Chow L.W.C., Practice of breast self-examination among high risk Chinese women in Hong Kong, Chinese Medical Journal. 2000, 113: 1100-1103.
Ng K.K.C., Chow L.W.C., Sentinel node biopsies in breast cancer, Annals of the College of Surgeons of Hong Kong. 2001, 5: 116-120.
Tsang F.H.F., Wong L.N., Chow L.W.C., Management of Impalpable breast cancer, 7th Hong Kong International Cancer Congress, Hong Kong, December 2000.


Researcher : Chow VWH
List of Research Outputs

Chow V.W.H., Yuen P.W., Lam K.Y., Tsao G.S.W., Ho W.K., Wei W.I., A comparative study of the clinicopathological significance of E-cadherin and catenins (a, b, g) expression in the surgical management of oral tongue carcinoma, Journal of Cancer Research and Clinical Oncology. 2001, 127: 59-63.
Chow V.W.H., Genes associated with invasion and metastasis of head and neck cancer, Thesis, Master of Philosophy, The University of Hong Kong. 2000.
Chow V.W.H., Yuen P.W., Lam B.K.Y., Ho W.K., Wei W.I., Prognostic significance of serum p53 protein and p53 antibody in patients with surgical treatment for head and neck squamous cell carcinoma, Head & Neck. 2001, 23: 286-291.
Chow V.W.H., Law S.Y.K., Lam K.Y., Luk J.M.C., Wong J., Telomerase activity in small cell esophageal carcinoma, Diseases of the Esophagus. 2001, 14: 139-142.


Researcher : Chu KM
List of Research Outputs

Chan A.O., Chu K.M., Kwok E., Lam S.K., Serum soluble E-cadherin is a good therapeutic monitoring marker in patients with gastric cancer after surgery, Gastroenterology. 2000, 118 (Suppl 2): A1384.
Chan A.O.O., Lam S.K., Chu K.M., Lam C.M., Kwok E.N.L., Leung S.Y., Yuen S.T., Law S.Y., Hui W.M., Lai K.C., Wong B.C.Y., Hu W.C.H., Lai C.L., Wong J., Soluble E-cadherin is a valid prognostic marker in gastric carcinoma., Gut. 2001, 48(6): 808-811.
Chan A.O.O., Lam S.K., Chu K.M., Lam C.M., Kwok E., Leung S.Y., Yuen S.T., Law S.Y.K., Hui W.M., Lai C.L., Wong C.Y., Hu H.C., Lai C.L., Wong J., Soluble E-cadherin is a valid prognostic marker in gastric carcinoma, Gut. 2001, 48: 808-811.
Chan A.O.O., Chu K.M., Yuen S.T., Leung S.Y., Lam S.K., Wong J., Synchronous gastric adenocarcinoma and mucosa-associated tissue lymphoma in association with Helicobacter pylori infection: comparing reported cases between the East and West, American Journal of Gastroenterology. 2001, 96: 1922-1924.
Chu K.M., Chairman, Gastric Cancer, State-of-the-Art Lecture, 7th Hong Kong International Cancer Congress, Faculty of Medicine, The University of Hong Kong, Hong Kong, December 7-9, 2000.
Chu K.M., Chairman, Gastric Cancer, Hong Kong Surgical Forum, Hong Kong, January 13-14, 2001. 2001.
Chu K.M., Chairman, Session on "New safety evidences of COX-2 specific inhibitors in arthritis management", Second Annual cientific Symposium of Centre of Alimentary Research & Education (CARE), Faculty of Medicine, The University of Hong Kong, December 10, 2000.
Chu K.M., Chairperson, Gastroenterology, The Joint Hong Kong Surgical & Medical Forum, Hong Kong, July 1, 2000.
Chu K.M., Deputy representative of the Department of Surgery for the Clinical Audit Subcommittee (April 1997 - June 2001), Queen Mary Hospital, Hong Kong, 2001.
Chu K.M., External Advisor / Reviewer, Quality Education Fund Projects (September 1999 - present), Quality Education Fund (QEF), Hong Kong, 2001.
Chu K.M., Gastric cancer, The First Joint Xian / Hong Kong Surgical Convention, Xian, China, July 3-4, 2000.
Chu K.M., Honorary Consultant in Gastrointestinal Surgery (March 1999 - present), Tung Wah Hospital, Hong Kong, 2001.
Chu K.M., Honorary Consultant, Department of Surgery (January 1999 - present), Queen Mary Hospital, Hong Kong, 2001.
Chu K.M., Intra-arterial chemotherapy for gastric cancer, 4th International Gastric Cancer Congress, New York, U.S.A., April 29 - May 2, 2001.
Chu K.M., Member of Editorial Board, Annals of Cancer Research and Therapy, 2000.
Chu K.M., Member, Advanced Trauma Life Support Course Subcommittee (January 1996 - present), The American College of Surgeons (Hong Kong Chapter), 2001.
Chu K.M., Member, Hospital Authority Working Group on Feasibility Study on Cyclotron-based PET Service in Hong Kong (December 1995 - present), Hospital Authority, 2001.
Chu K.M., Member, Queen Mary Hospital Working Group on PET (November 1995 - present), Queen Mary Hospital, 2001.
Chu K.M., Member, The Hong Kong Committee on Trauma (December 1995 - present), The American College of Surgeons, 2001.
Chu K.M., Member, The Hospital Authority Head Office (HAHO) Task Force on the Development of Cinical Referral Guidelines for Positron Emission Tomography (PET) (Septebmer 1999 - present), Hospital Authority, 2001.
Chu K.M., Member, The Hospital Authority Head Office (HAHO) Task Force on the Development of Clinical Practice Guidelines on Upper GI Bleeding (June 1999 - present), Hospital Authority, 2001.
Chu K.M., Member, Working Group on Rational Prescribing of Drugs (January 1996 - 2000), Queen Mary Hospital, Hong Kong, 2001.
Chu K.M., Moderator, Gastric Cancer - Case Presentation, Hong Kong Surgical Forum, Hong Kong, January 13-14, 2001. 2001.
Chu K.M., Moderator, Gastro-esophageal - Case Presentation, Hong Kong Surgical Forum, Hong Kong, July 1, 2000.
Chu K.M., Kwok K.F., Law S.Y.K., Wong J., One-week once-daily triple therapy for Helicobacter pylori - a pilot study, Hepatogastroenterology. 2000, 47: 1624-1626.
Chu K.M., Palliative treatment for gastric cancer, Hong Kong Surgical Forum, Hong Kong, January 13-14, 2001.
Chu K.M., Regional Faculty, Advanced Trauma Life Support Course (January 1996 - present), American College of Surgeons (Hong Kong Chapter), 2001.
Chu K.M., Regional intra-arterial chemotherapy for advanced gastric cancer, The Second Annual Scientific Symposium of Centre of Alimentary Research & Education (CARE), Faculty of Medicine, The University of Hong Kong, Hong Kong, December 10, 2000.
Lai K.C., Chu K.M., Hui W.M., Wong C.Y., Hu W., Yuen M.F., Chan O.O., Lai C.L., Lau K.K., Chan C.K., Lam S.K., COX-2 inhibitor compared with proton pump inhibitor in the prevention of recurrent ulcer complications in high-risk patients taking NSAIDs, Gastroenterology. 2001, 120(5) Suppl: 551.
Lai K.C., Chu K.M., Hui W.M., Wong C.Y., Hu W., Wong W.M., Yuen M.F., Chan O.O., Lai C.L., Lau K.K., Chan C.K., Lam S.K., COX-2 inhibitor compared with proton pump inhibitor in the prevention of recurrent ulcer complications in high-risk patients taking NSAIDs, The Annual Meeting of the American Gastroenterological Association, Digestive Disease Week (DDW), Atlanta, Georgia, USA, May 20-23, 2001.
Lai K.C., Lam S.K., Hui W.M., Wong C.Y., Chu K.M., Wong W.M., Chan O.O., Lai C.L., Lau K.K., Yuen M.F., Chan C.K., Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in NSAIDs users, Gastroenterology. 2000, 118(Supp 2): A251.
Lai K.C., Lam S.K., Chu K.M., Hui W.M., Wong C.Y., Hu W., Wong W.M., Yuen M.F., Chan O.O., Lai C.L., Lau K.K., Chan C.K., Helicobacter pylori eradication vs combined proton pump inhibitor and Helicobacter pylori eradication in the prevention of recurrent peptic ulcer complications in high-risk patients receiving low-dose aspirin, Gastroenterology. 2001, 120(5) Suppl: 550.
Lai K.C., Lam S.K., Chu K.M., Hui W.M., Wong C.Y., Hu W., Wong W.M., Yuen M.F., Chan O.O., Lai C.L., Lau K.K., Chan C.K., Helicobacter pylori eradication vs combined proton pump inhibitor and Helicobacter pylori eradication in the prevention of recurrent peptic ulcer complications in high-risk patients receiving low-dose aspirin, The Annual Meeting of the American Gastroenterological Association, Digestive Disease Week (DDW), Atlanta, Georgia, USA, May 20-23, 2001.
Lai K.C., Lam S.K., Chu K.M., Hui W.M., Wong B.C.Y., Wong W.M., Yuen M.F., Chan O.O., Lai C.L., Lau G.K.K., Chan C.K., Helicobacter pylori eradication vs Helicobacter pylori eradication combined with proton pump inhibitor in prevention of aspirin induced peptic ulcer complications, The 6th Medical Research Conference, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, January 13-14, 2001.
Lai K.C., Lam S.K., Chu K.M., Hui W.M., Wong B.C.Y., Hu W.H.C., Wong W.M., Yuen M.F., Chan O.O., Lai C.L., Lau G.K.K., Chan C.K., Helicobacter pylori eradication vs Helicobacter pylori eradication combined with proton pump inhibitor in prevention of aspirin induced peptic ulcer complications, The Hong Kong Practitioner. 2001, 23 (Suppl): 20.
Law S.Y.K., Fok M., Wei W.I., Lam L.K., Tung P.H.M., Chu K.M., Wong J., Thoracoscopic esophageal mobilization for pharyngolaryngoesophagectomy, Annals of Thoracic Surgery. 2000, 70: 418-422.
Law W.L., Chu K.W., Ho J.W.C., Tung H.M., Law S.Y.K., Chu K.M., Self-expanding metallic stent in the treatment of colonic obstruction due to advanced malignancies, Diseases of Colon and Rectum. 2000, 43: 1522-1527.
Lee Y.M., Law S.Y.K., Chu K.M., Wong J., Pyloroplasty in gastric replacement of the esophagus after esophagectomy: one-layer or two-layer technique?, Diseases of the Esophagus. 2000, 13: 203-206.
Ng F.Y., Chu K.M., Percutaneous endoscopic gastrostomy, Departmental Journal Review. 2000.
Ng K.K.C., Chu K.M., Helicobacter pylori infection and duodenal ulcer perforation, Asian Journal of Surgery. 2001, 24: 197-202.
Sieh K.M., Chu K.M., Wong J., Intra-abdominal hypertension and abdominal compartment syndrome, Langenbeck's Archives of Surgery. 2001, 386: 53-61.
Tsang H.F., Chu K.M., Gastrointestinal bleeding of obscure origin, Departmental Journal Review. 2001.
Tsui W.Y., Leung S.Y., Yuen S.T., Ho S.H., Chan A.S.Y., Chu K.M., Chung L.P., Suppression subtractive hybridization and differential screening identified genes differentially expressed in gastric carcinomas, Proceedings of American Association Cancer Research. 2000, 41: 680.
Tung P.H.M., Law S.Y.K., Chu K.M., Law W.L., Wong J., Gastric rupture after Heimlich manoeuver and cardiopulmonary resuscitation, Hepato-Gastroenterology. 2001, 48: 109-111.
Wong B.C.Y., Wong W.M., Wang W.H., Fung F.M.Y., Lai K.C., Chu K.M., Yuen S.T., Leung S.Y., Hu H.C., Yuen M.F., Lau G., Chan C.K., Lam S.K., One-week Ranitidine Bismuth Citrate-based triple therapy for the eradication of Helicobacter pylori in Hong Kong with high prevalence of metronidazole resistance, Alimentary Pharmoacology and Therapeutics. 2001, 15: 403-409.
Wong B.C.Y., Wang W.H., Lau G., Wong W.M., Fung F.M.Y., Kung N.N.S., Chu K.M., Lai K.C., Hu H.C., Hu F.L., Liu X.G., Chan C.K., Yuen M.F., Hui W.M., Lam S.K., Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized contolled study [Oral presentation, 6th Medical Research Conference, Department of Medicine, 13-14 January], The Hong Kong Practitioner. 2001, 23 (2-suppl): 18.
Wong B.C.Y., Wang W.H., Lau G.K.K., Wong W.M., Fung F.M.Y., Kung N.N.S., Chu K.M., Lai K.C., Hu W.H.C., Hu F.L., Liu X.G., Chan C.K., Yuen M.F., Hui W.M., Lam S.K., Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized controlled study, The 6th Medical Research Conference, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, January 12 - 14, 2001.
Wong B.C.Y., Wang W.H., Wong W.M., Lau G.K.K., Fung F.M.Y., Kung S.N.N., Chu K.M., Lai K.C., Hu F.L., Liu X.G., Chan C.K., Yuen M.F., Hui W.M., Lam S.K., Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized controlled study, Alimentary Pharmacology and Therapeutics. 2001, 15: 843-850.
Wong W.M., Lam S.K., Wang W.H., Lau G.K.K., Kung N.N.S., Chu K.M., Lai K.C., Hu W., Hu F.L., Liu X.G., Yuen M.F., Wong B.C.Y., Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized controlled study, Annual Meeting of the American Gastroenterological Association, Digestive Disease Week (DDW), Atlanta, Georgia, USA, May 20-23, 2001.
Wong W.M., Lam S.K., Wang W.H., Lau G.K., Kung N.N., Chu K.M., Lai K.C., Hu W.H., Hu F.L., Liu X.G., Yuen M.F., Wong B.C., Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized controlled study, Gastroenterology. 2001, 120(5) Suppl: 2959.
Zhou H., Chan K.L., Chu K.M., Tam P.K.H., Intrafamilial spread of Helicobacter pylori: a prospective study using urea breath test, Journal of Pediatric Surgery. 2000, 35: 1672-1675.


Researcher : Chu KW
List of Research Outputs

Chan R.T.T., Au G.K.H., Ho J.W.C., Chu K.W., Radiation recall with oxaliplatin: report of a case and a review of the literature, Clinical Oncology. 2001, 13: 55-57.
Chu K.W., Law W.L., Recurrence after rectal cancer operation, Chinese Journal of Gastrointestinal Surgery. 2000, 3: 209-212.
Law W.L., Chu K.W., Ho J.W.C., Tung H.M., Law S.Y.K., Chu K.M., Self-expanding metallic stent in the treatment of colonic obstruction due to advanced malignancies, Diseases of Colon and Rectum. 2000, 43: 1522-1527.
Lee Y.M., Law W.L., Chu K.W., Abdominal actinomycosis: report of 3 cases, The Australian and New Zealand Journal of Surgery. 2001, 71: 261-263.
Lee Y.M., Law W.L., Chu K.W., Poon R.T.P., Emergency surgery for obstructing colorectal cancers: a comparison between right-sided and left-sided lesions, Journal of American College of Surgery. 2001, 192: 719-725.


Researcher : Chu SSM
List of Research Outputs

Ho K.L., Leung S.Y.L., Cheung M.C., Wong B.B.W., Chu S.S.M., Lee F.C.W., Tam P.C., An audit of urological day surgery service - a 5-year experience in the Day Surgery Centre in Tung Wah Hospital, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Leung S.Y.L., Cheung M.C., Wong B.B.W., Chu S.S.M., Lee F.C.W., Tam P.C., Same day transurethral resection - vaporization of the prostate (TURVP) for the treatment of benign prostatic hyperplasia, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Wong B.B.W., Cheung M.C., Leung S.Y.L., Ho K.L., Chu S.S.M., Lee F.C.W., Tam P.C., The value of noncontrast helical computer tomography in the diagnosis of acute ureteric colic, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Wong T.Y., Chu S.S.M., Management of pelvic fracture urethral injury: the controversies, Departmental Journal Review. 2000.


Researcher : Chung HP
List of Research Outputs

Chan T.L., Chan Y., Cheng F., Cheung A.C.S., Ho K.T., Hui P.K., Chung H.P., Reducing burn mortality in the turn of the century, Departmental Journal Review. 2000.
Hung G.B.K., Baig N.B., Wat Y.M., Wong S.M., Foo C.C., Mui C.Y., Chung H.P., Guidelines for office-based surgery, Departmental Journal Review. 2001.
Lam L.K., Hui Y., Ng W.M., Chung H.P., Li K.H., A new method of revision of peri-tracheostomal scar together with closure of tracheo-cutaneous fistula, 7th International Congress of Oriental Aesthetic Plastic Surgery, Seoul, Korea, October 2000.
Lee P.P.W., Luk H.M., Ngai W.S., Tam P.M.K., Tin L.N.W., Chung H.P., Prognostic indicators in acute pancreatitis, Departmental Journal Review. 2001.
Wong S.Y., Chan S.H., Lam L.K., Ng W.M., Li K.H., Chung H.P., Aesthetic considerations in the surgical management of Madelung's disease, 7th International Congress of Oriental Aesthetic Plastic Surgery, Seoul, Korea, October 2000.


Researcher : Fan ST
Project Title:Artificial liver support for patients with liver failure in Hong Kong
Investigator(s):Prof. Fan S.T.
Department:Surgery
Source(s) of Funding:Oriental Press Charitable Fund Association
Start Date:December 1993
Completion Date:December 2000
Abstract:
To establish a system of artificial liver for treatment of terminal liver failure.


Project Title:Liver transplantation in Hong Kong
Investigator(s):Prof. Fan S.T.
Department:Surgery
Source(s) of Funding:Oriental Press Charitable Fund Association
Start Date:July 1995
Abstract:
To evaluate the outcome of liver transplantation in Hong Kong.


Project Title:Prolongation of liver graft survival in the absence of immunosuppressive drugs in a rat model via CTLA4Ig gene transfer
Investigator(s):Prof. Fan S.T. , Dr. Cheung S.T.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1999
Completion Date:June 2001
Abstract:
1) Construction of a retroviral vector for expression of CTLA4Ig. 2) Targeting to express the CTLA4Ig protein in the rat liver graft. 3) Examination of the tolerance of the allografted liver that has been transduced with the CTLA4Ig.


Project Title:Adult-to-adult living donor liver transplantation using extended right lobe graft for patients with end-stage liver diseases
Investigator(s):Prof. Fan S.T.
Department:Surgery
Source(s) of Funding:RGC Fundable Projects (Block Grant Funded)
Start Date:February 2000
Abstract:
To establish the adult-to-adult living donor liver transplantation using extended right lobe graft as a standard procedure for treatment with terminal liver diseases; to assess the value of adult-to-adult living donor liver transplantation using extende d right lobe graft in reducing the mortality rate of adult patents waiting for liver transplantation.


Project Title:Right-sided hepatectomy for hepatocellular carcinoma by anterior approach - a prospective randomized trial
Investigator(s):Prof. Fan S.T.
Department:Surgery
Source(s) of Funding:Hong Kong Research Grants Council Competitive Earmarked Research Grants
Start Date:September 2000
Abstract:
To carry out a prospective randomised trial on patients operated by anterior approach and conventional approach, and compare which is the better practice in liver surgery.


Project Title:S.K. Yee Medical Foundation Fellowship in hepatobiliary surgery
Investigator(s):Prof. Fan S.T.
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation Grant
Start Date:November 2000
Abstract:
To train surgeons from less developed cities in China to acquire the technique and knowledge in dealing with complex hepatobiliary problems so as to benefit patients who cannot afford the cost of receiving treatment in cities like Beijing, Shanghai and Guangzhou.


List of Research Outputs

Au W.Y., Ma E.S.K., Kwong Y.L., Ng I.O.L., Hawkins B.R., Wan T.S.K., Liu C.L., Fan S.T., Lo C.M., Graft versus host disease after liver transplantation: documentation by FISH and HLA typing., Clinical Transplantation. 2000, 14: 173-176.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Liver transplantation is not contraindicated in infancy, Transplantation Proceedings. 2000, 32(7): 2142-2143.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Post liver transplantation stenosis of biliary-enteric anastomoses in infancy: diagnosis and treatment, Transplantation Proceedings. 2000, 32(7): 2233-2234.
Chen X., Cheung S.T., Barry C., Fan S.T., Lai K.M., Ji F.J., Praprong W., Botstein D., Brown P., So S., Genome-wide study of human hepatocellular carcinoma with 23K cDNA microarray, The 51st Annual Meeting and Postgraduate Courses of the American Association for the Study of Liver Diseases. Dallas, Texas, USA. Hepatology, 2000.
Cheung S.T., Chen X., Fan S.T., So S., Ng I.O., Brown P., Genome-wide expression profiling of hepatocellular carcinoma by cDNA microarray technology, 7th Hong Kong International Cancer Congress. 2000.
Cheung S.T., Chen X., Fan S.T., So S., Ng I.O.L., Brown P., Molecular characterization of hepatocellular carcinoma by cDNA microarray, Proceedings of the American Association for Cancer Research. 2001, 42: 3285.
Cheung S.T., Chen X., Fan S.T., So S., Ng I.O., Brown P., Molecular characterization of hepatocellular carcinoma by cDNA microarray, The 92nd Annual Meeting of the American Association for Cancer Research. New Orleans, Los Angeles, USA. 2001.
De Villa V.H., Chen C.L., Chen Y.S., Wang C.C., Wang S.H., Chiang Y.C., Cheng Y.F., Huang T.L., Jawan B., Cheung H.K., Fan S.T., Lo C.M., International sharing of split liver grafts in Asia: initial experience, Clinical Transplantation. 2000, 14: 355-359.
De Villa V.H., Chen C.L., Chen Y.S., Wang C.C., Tan K.C., Suh K.S., Lee S.G., Tanaka K., Fan S.T., Split liver transplantation in Asia, Transplantation Proceedings. 2001, 33: 1502-1503.
Fan S.T., Wong J., "No-touch" surgery for hepatobiliary cancer, Scientific News Section, World Gastroenterology News. 2000, Spring: 21-23.
Fan S.T., A review on the experience at Queen Mary Hospital on the different treatments for hepatocellular carcinoma (Invited Lecture), 34th SPG Forum, International, Miyasaki, Japan, November 30-December 1, 2000.
Fan S.T., Anti-viral treatment for HBV in liver transplantation (Invited Lecture), Prograf Okinawa Summit, Okinawa, Japan, February 25, 2001.
Fan S.T., Case discussions on HCC management (Invited Lecture), 32nd World Congress of the International College of Surgeons, Singapore, October 8-12, 2000.
Fan S.T., Chairman, Transplant Centre, Queen Mary Hospital, Hong Kong, 2001.
Fan S.T., Complication of bilio-enteric anastomosis (Invited Lecture), Living Donor Liver Transplantation Symposium, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, February 10, 2001.
Fan S.T., Consultant Surgeon, Queen Mary Hospital and Tung Wah Hospital, Hospital Authority, Hong Kong, 2001.
Fan S.T., Council Member (1993 - present), The Hong Kong Liver Foundation, 2001.
Fan S.T., Distinguished Research Achievement Award, 2000 - 2001, The University of Hong Kong, 2001.
Fan S.T., Donor safety and minimum remaining volume (Invited Lecture), Living Donor Liver Transplantation Symposium, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, February 10, 2001.
Fan S.T., Donor safety in living donor liver transplantation (Comment to Editorial), Liver Transplantation. 2000, 6: 250-251.
Fan S.T., Expert Clinician, Phoenix Alliance, USA, 2001.
Fan S.T., Hepatocellular carcinoma management - problems, solutions & predictions (Invited Lecture), 32nd World Congress of the International College of Surgeons, Singapore, October 8-12, 2000.
Fan S.T., Living donor liver transplantation in Hong Kong (Invited Lecture), 3rd Roche Asian Transplantation Forum, Taipei, Taiwan, April 28-29, 2001.
Fan S.T., Member at large to Executive Committee, International Gastro-Surgical Club, 2001.
Fan S.T., Member of Editorial Board, 2001.
Fan S.T., Member of Editorial Board, 2001.
Fan S.T., Member of Editorial Board, 2001.
Fan S.T., Member of Editorial Board, 2001.
Fan S.T., Member of Editorial Board, 2001.
Fan S.T., Member of Editorial Board, 2001.
Fan S.T., Member of Editorial Board (1991 - present), Journal of Gastroenterology and Hepatology, 2001.
Fan S.T., Member of Editorial Board (1993 - present), HPB Surgery, 2001.
Fan S.T., Member of Editorial Board (1995 - present), Hepato-Gastroenterology, 2001.
Fan S.T., Member of Editorial Board (January 1993 - present), Hong Kong Practitioner, 2001.
Fan S.T., Member of Editorial Board (January 2000 - present), 2001.
Fan S.T., Member of Editorial Board (January 2000 - present), Asian Journal of Surgery, 2001.
Fan S.T., Member of Editorial Board (January 2000 - present), Chinese Medical Journal, 2001.
Fan S.T., Member of Editorial Board (July 1999 - present), HPB, 2001.
Fan S.T., Member of Editorial Board (July 1999 - present), Liver Transplantation, 2001.
Fan S.T., Member of Editorial Board, Journal of Cancer Research and Clinical Oncology, 2001.
Fan S.T., Member of Editorial Board, Digestive Surgery, 2001.
Fan S.T., Member of Editorial Board, Nutrition, 2001.
Fan S.T., Member, Criminal and Law Enforcement Injuries Compensation Board (June 1995 - present), Social Welfare Department, Hong Kong Government, 2001.
Fan S.T., Member, Subcommittee of Services Development in Surgery, Hospital Authority, Hong Kong, 2001.
Fan S.T., National Delegate, International Society of Surgery (ISS) Societe Internationale de Chirurgie (SIC), 2001.
Fan S.T., Organiser, Donor Liver Transplantation Symposium 2001, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, February 10, 2001.
Fan S.T., Peer Reviewer, American Journal of Gastroenterology, 2001.
Fan S.T., Peer Reviewer, American Journal of Surgery, 2001.
Fan S.T., Peer Reviewer, Annals of Surgery, 2001.
Fan S.T., Peer Reviewer, Asian Journal of Surgery, 2001.
Fan S.T., Peer Reviewer, Digestive Surgery, 2001.
Fan S.T., Peer Reviewer, Journal of Cancer Research and Clinical Oncology, 2001.
Fan S.T., Peer Reviewer, Journal of Hepato-Biliary-Pancreatic Surgery, 2001.
Fan S.T., Peer Reviewer, Nutrition, 2001.
Fan S.T., Peer Reviewer, Archieves of Surgery, 2001.
Fan S.T., Peer Reviewer, British Journal of Surgery, 2001.
Fan S.T., Peer Reviewer, HBP Surgery, 2001.
Fan S.T., Peer Reviewer, Intensive Care Medicine, 2001.
Fan S.T., Peer Reviewer, Journal of Gastroenterology and Hepatology, 2001.
Fan S.T., Peer Reviewer, Surgery, 2001.
Fan S.T., Pitfall of surgical technique of living donor liver transplantation in adult recipients, Prograf Okinawa Summit, Okinawa, Japan, February 25, 2001.
Fan S.T., Preoperative estimation of the surgical risk (Invited Lecture), 2nd Meeting of Hepatocellular Carcinoma Eastern and Western Experiences, Tokyo, Japan, December 9, 2000.
Fan S.T., Wong J., Recurrent pyogenic cholangitis, In: Blumgart L.H. and Fong Y. , Surgery of the Liver and Biliary Tract. London, W.B. Saunders, 2000, volume II; 3rd edition: 1205-1225.
Fan S.T., Results of living donor liver transplantation in Hong Kong (Invited Lecture), 9th Keio University International Symposium for Life Sciences and Medicine, Current Issues in Liver/Small Bowel Transplantation, Keio University, Tokyo, Japan, March 23-24, 2001.
Fan S.T., Results with living donor liver transplantation in Hong Kong (Invited Lecture), Workshop on Living Donor Liver Transplantation, Bethesda, USA, December 4-5, 2000.
Fan S.T., Right hepatic duct stenosis and leakage in right lobe graft living donor liver transplantation (Invited Lecture), Living Donor and Split Liver Transplantation Symposium, Rome, Italy, August 26, 2000.
Fan S.T., Right lobe live donor liver transplantation improves survival of patients with acute liver failure (Invited Lecture), 2nd Annual Scientific Meeting of the Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, February 17-18, 2001.
Fan S.T., Surgical approaches in liver transplantation (Invited Lecture), 1st Workshop for Clinical Liver Transplantation in China, Shanghai, China, September 27-28, 2000.
Fan S.T., Surgical debate: HCC management - liver transplantation or resection? For resection (Invited Lecture), 32nd World Congress of the International College of Surgeons, Singapore, October 8-12, 2000.
Fan S.T., TACE (Invited Lecture), 32nd World Congress of the International College of Surgeons, Singapore, October 8-12, 2000.
Fan S.T., Visiting Professor and Consultant, 中國北京, 中國人民解放軍總醫院, 中國人民解放重軍區進修學院, April, 2001.
Fan S.T., Visiting Professor and Consultant, 中國安徽醫科大學附屬醫院, June, 2001.
Fan S.T., Visiting Professor and Consultant, 中國重慶第二軍醫大學附屬西南醫院, November, 2000.
Fan S.T., Visiting Professorship and Consultancy, Cleveland Clinic Foundation, Ohio, USA, 2001.
Fan S.T., 肝細胞肝癌療法(講學), 中國安徵省合肥市安徽醫科大附屬醫症普外科, June 7-8, 2001.
Fan S.T., 肝臟移植進展, 香港及外國經驗 - 新世紀面臨的機遇與挑戰, 第五屆全普通外科中青年醫師學術交流會暨第八屆全國普通外科學術會議, 中國寧波, September 25, 2000.
Fan S.T., 治療肝細胞肝癌的肝臟移植-香港經驗, 全國日達仙腫瘤會議, 中國上海, April 21, 2001.
Fan S.T., 急性肝衰竭- 處理和手術, 第五屆全國肝膽胰脾外科新進展新技術學術年會, 中國深圳, April 25-29, 2001.
Fan S.T., 王偉林 , 活體肝移植外科處理, 2000, 6: 253-255.
Fan S.T., 香港地區肝臟移植, 第六屆全國肝臟外科學術會議, 中國武漢, October 25-28, 2000.
Fan S.T., 香港活體肝臟移植經驗總結, 中國人民解放軍醫進修學院/中國人民解放軍總醫院, 中國北京, April 4-6, 2001.
Lam B.K., Lo C.M., Fung A.S., Fan S.T., Liu C.L., Wong J., Marital adjustment after interspouse living donor liver transplantation, Transplantation Proceedings. 2000, 32: 2095-2096.
Lee K.W., Han J.S., Fan S.T., Liang Z.D., Tian P.K., Gu J.R., Ng I.O.L., Gene delivery using a receptor-mediated gene transfer system targeted to hepatocellular carcinoma cells, International Journal of Cancer. 2001, 93: 393-400.
Li N., Kumana C.R., Cheung B.M.Y., Fan S.T., Liu C.L., Age affects blood pressure and heart rate following IV diazepam, VII World Conference on Clinical Pharmacology & Therapeutics 4th Congress of the European Association for Clinical Pharmacology & Therapeutics. 2001.
Liu C.L., Fan S.T., Acute cholangitis, In: Holzheimer R.G. and Mannick J.A., Surgical Treatment - Evidence Based and Problem-Oriented. New York, W Zuckschwerdt Verlag, 2001, 366-371.
Liu C.L., Fan S.T., Lo C.M., Poon R.T.P., Wong J., Anterior approach for major right hepatic resection for large hepatocellular carcinoma, Annals of Surgery. 2000, 232: 25-31.
Liu C.L., Lo C.M., Fan S.T., Endoscopic ultrasonography in pancreatitis (Review Article), Annals of the College of Surgeons of Hong Kong. 2000, 4: 145-148.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), American Journal of Transplantation. 2001, 1(Suppl 1): 261:A502.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Lo C.M., Fan S.T., Endocrine tumours of the pancreas, Annals of the College of Surgeons of Hong Kong. 2001, 5: 110-115.
Lo C.M., Fan S.T., Wong J., Intrahepatic stones, In: Morris P.J. and Wood W.C. (eds.) , Oxford Textbook of Surgery. New York, USA, Oxford University Press Inc., 2000, 2nd edition: 3357-3360.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis., Annas ofl Surgery. 2001, 233(2): 276-281.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis, Annals of Surgery. 2001, 233: 276-281.
Lo C.M., Fan S.T., Liu C.L., Lai C.L., Lau G.K.K., Yong B.H., Ng I.O.L., Young K., Chan J.C.K., Wong J., Liver transplantation in Hong Kong - a wider application., Transplantation Proceedings. 2000, 32(7): 2141.
Lo C.M., Fan S.T., Liu C.L., Lai C.L., Lau G.K.K., Yong B.H., Ng I.O.L., Young K., Chan J.K., Wong J., Liver transplantation in Hong Kong - a wider application, Transplantation Proceedings. 2000, 32: 2141.
Lo C.M., Fan S.T., Living donor liver transplantation in adults, Graft. 2000, 3: 260-264.
Lo C.M., Fan S.T., Living donor liver transplantation: donor selection, evaluation, and surgical complications, Current Opinion in Organ Transplantation. 2001, 6: 120-125.
Lo C.M., Fan S.T., Liu C.L., Ng I.O.L., Lam B.K., Yong B.H., Lai C.L., Lau G.K.K., Wong J., More effective immunosuppression with the use of FK506 after liver transplantation., Transplantation Proceedings. 2000, 32(7): 2269-2270.
Lo C.M., Fan S.T., Liu C.L., Ng I.O.L., Lam B.K., Yong B.H., Lai C.L., Lau G.K., Wong J., More effective immunosuppression with the use of FK506 after liver transplantation, Transplantation Proceedings. 2000, 32: 2269-2270.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 373:A944.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Lo C.M., Fan S.T., Surgical techniques in right lobe liver transplantation, Transplantation Proceedings. 2000, 32: 1512-1513.
Lo C.Y., Fan S.T., Endocrine tumours of the pancreas, Annals of Endocrine Surgery (Indian). 2000, 5: 23-28.
Lo C.Y., Lo C.M., Fan S.T., Role of laparoscopic ultrasonography in intraoperative localization of pancreatic insulinoma, Surgical Endoscopy - Ultrasound and Interventional Techniques. 2000, 14: 1131-1135.
Lo C.Y., Chan F.L., Tam S.C.F., Cheng P.W., Fan S.T., Lam K.S.L., Value of intra-arterial calcium injection with hepatic venous sampling for regionalisation of pancreatic insulinomas., Surgery. 2000, 128: 903-9.
Luk J.M.C., Tam P.K.H., Fan S.T., Koo M.W.L., Immunosuppressive effects of tripterygium wilfordii polysaccharide on LPS-stimulated human monocytes, Transplantation Proceedings. 2000, 32: 2013-2015.
Man K., Fan S.T., Lo C.M., Wong J., Graft injury correlated with portal hemodynamics and intra graft endothelin-1 expression in living donor liver transplantaion in relation to graft size (Abstract), The Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Man K., Fan S.T., Lo C.M., Wong J., Graft injury correlated with portal hemodynamics and intra graft endothelin-1 expression in living donor liver transplantation in relation to graft size (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 369:A926.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L., Fan S.T., Wong J., Liver transplantation in rats using small-for-size grafts - a study of hemodynamic and morphological changes, Archives of Surgery. 2001, 136: 280-285.
Man K., Fan S.T., Pringle manoeuvre during hepatectomy, Asian Journal of Surgery. 2001, 24: 70-77.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L.F., Fan S.T., Wong J., The mechanism of small-for-size graft injury after liver transplantation, Fourth Shanghai International Symposium on Liver Cancer and Hepatitis and the Second Scientific Meeting of Cheng Si-Yuan (China International) Hepatitis Research Foundation, Pudong, Shanghai, China, September 23-26, 2000.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L.F., Fan S.T., Wong J., The mechanism of small-for-size graft injury after liver transplantation, Journal of Gastroenterology and Hepatology. 2000, 15: 1139 (O-L-7).
Ng I.O.L., Liu C.L., Fan S.T., Ng M., Expression of P-glycoprotein in hepatocellular carcinoma. A determinant of chemotherapy response, Anatomic Pathology. 2000, 113: 355-363.
Ng I.O.L., Fan S.T., Is the p53 gene mutation of prognostic value in hepatocellular carcinoma?, Archives of Surgery. 2000, 135: 1476.
Ng I.O.L., Shek T.W.H., Thung S.N., Ye M.M.Q., Lo C.M., Fan S.T., Lee M.F., Chan K.W., Cheung A.N.Y., Microsatellite analysis in post-transplantation lymphoproliferative disorder to determine donor/recipient origin, Modern Pathology. 2000, 13(11): 1180-1185.
Poon R.T.P., Fan S.T., Yu W.C., Lam B.K.Y., Chan F.Y.S., Wong J., A prospective longitudinal study of quality of life after resection of hepatocellular carcinoma, Archives of Surgery. 2001, 136: 693-699.
Poon R.T.P., Ng I.O.L., Lau C., Fan S.T., Wong J., Clinical and prognostic significance of microvessel density in hepatocellular carcinoma: a prospective study (Abstract), Proceedings of the Angiogenesis and Cancer: From Basic Mechanisms to Therapeutic Applications, Michigan, U.S.A., 2000.
Poon R.T.P., Ng I.O.L., Lau C., Fan S.T., Wong J., Clinical and prognostic significance of microvessel density in hepatocellular carcinoma: a prospective study, Proceedings of American Association for Cancer Research, Traverse City, USA, October 11-15, 2000.
Poon R.T.P., Fan S.T., Wong J., Clinical implications of circulating angiogenic factors in cancer patients (Review Article), Journal of Clinical Oncology. 2001, 19(4): 1207-1225.
Poon R.T.P., Ng I.O.L., Fan S.T., Lai E.C.S., Lo C.M., Liu C.L., Wong J., Clinicopathologic features of long-term survivors and disease-free survivors after resection of hepatocellular carcinoma: a study of a prospective cohort, Journal of Clinical Oncology. 2001, 19(12): 3037-3044.
Poon R.T.P., Fan S.T., Ng I.O.L., Lo C.M., Liu C.L., Wong J., Different risk factors and prognosis of early and late intrahepatic recurrence after resection of hepatocellular carcinoma, Cancer. 2000, 89: 500-507.
Poon R.T.P., Fan S.T., Hepatocellular carcinoma, In: Yuri A.P. (ed.), Hepatic Surgery (Cirugia Hepatica) (Chile). 2000, 131-140.
Poon R.T.P., Fan S.T., Interval laparoscopic cholecystectomy in the management of acute biliary pancreatitis (Invited Commentary), HBP Surgery. 2000, 11: 322-323.
Poon R.T.P., Fan S.T., Liver disease and parental nutrition, In: Rombeau J.L. and Rolandelli R. H. (eds.), Clinical Nutrition, Parenteral Nutrition. Philadelphia, USA, W.B. Saunders, 2001, 3rd edition: 392-406.
Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Ng I.O.L., Wong J., Long-term prognosis after resection of hepatocellular carcinoma associated with hepatitis B-related cirrhosis, Journal of Clinical Oncology. 2000, 18: 1094-1101.
Poon R.T.P., Liu C.L., Lo C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy (Abstract), Digestive Disease Week 2000, San Diego, U.S.A. 2000.
Poon R.T.P., Liu C.L., Lo C.M., Lam C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy, Archives of Surgery. 2001, 136: 11-16.
Poon R.T.P., Fan S.T., Opinions and commentary on treating pancreatic cancer, Surgical Clinics of North America. 2001, 81: 625-636.
Poon R.T.P., Fan S.T., Wong J., Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma, Annals of Surgery. 2000, 232: 10-24.
Poon R.T.P., Ng I.O.L., Lau C., Zhu L.X., Yu W.C., Lo C.M., Fan S.T., Wong J., Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: a prospective study, Annals of Surgery. 2001, 233: 227-235.
Saing H., Fan S.T., Wei W.I., Chan K.L., Lo C.M., Mya G.H., Tsoi N.S., Yuen K.Y., Ng I.L.O., Chau M.T., Tso W.K., Chan J.F.K., Wong J., Pediatric liver transplantation: the Hong Kong experience, 6th Congress of the Cambodian Surgical Society, Cambodia, October 25-26, 2000.
Saing H., Fan S.T., Chan K.L., Wei W.I., Lo C.M., Mya G.H., Wong J., Portoenterostomy complimented by liver transplantation for biliary atresia: the Queen Mary Hospital, Hong Kong experience, 6th Congress of the Cambodian Surgical Society, October 25-26, 2000.
Wong C.M., Fan S.T., Ng I.O.L., Mutation and expression of b-Catenin gene in hepatocellular carcinoma - clinicopatholgical and prognostic significance, 7th Hong Kong International Cancer Congress, Hong Kong, December 7-9, 2000.
Wong C.M., Fan S.T., Ng I.O.L., b-Catenin mutation and expression in HCC - clinicopathological and prognostic significance, The Second Annual Scientific Meeting of the Centre for the Study of Liver, The University of Hong Kong, Hong Kong, 17-18 February. 2001.
Wong C.M., Fan S.T., Ng I.O.L., b-Catenin mutation and overexpression in hepatocellular carcinoma, Cancer. 2001, 92(1): 136-145.
Yang Z., Wu X., Tsui T.Y., Hou Y., Luk J.M.C., Fan S.T., Low-dose FK506 can enhance the effects of recombinant adeno-associated virus mediated hcTLA-4Ig gene transfer, AST/ASTS Transplant 2001 Meeting, A951098. 2001.
Yong B.H., Tsui S.L., Leung C.C., Lo C.M., Liu C.L., Fan S.T., Young K., Management of postoperative analgesia in living liver donors, Transplantation Proceedings. 2000, 32: 2110.
Yuen W.K., Chen Y.B., Fan S.T., 肝臟移植術, 許業珍, 江朝光編. 軍事醫學科學出版社, 2000, 408-417.
Zhu L.X., Geng X.P., Fan S.T., Spontaneous rupture of hepatocellular carcinoma and vascular injury, Archives of Surgery. 2001, 136: 682-687.
王偉林 , Fan S.T., 活動肝移植的供肝切取手術40例臨床分析, 2000, 15: 521-523.
朱遠方 , Fan S.T., 肝移植中肝靜脈吻合方法的比較, 2000, 6: 297-298.
張志偉 , Fan S.T., 再次肝移植6例報道, 2000, 11: 1-2.
張志偉 , Fan S.T., 肝臟移植治療肝癌8例, 2000, 38: 415-417.


Researcher : Fan YW
List of Research Outputs

Fan Y.W., Leung G.K.K., The use of MRI CSF flow studies in neurosurgery, Journal of the Hong Kong College of Radiologists. 2000, 3 (Suppl.): 165-169.
Leung S.Y., Yuen S.T., Chan T.L., Chan A.S.Y., Ho J.W.C., Kwan K.Y.M., Fan Y.W., Hung K.N., Chung L.P., Wyllie A.H., Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation, Oncogene. 2000, 19: 4079-4083.


Researcher : Fok M
List of Research Outputs

Law S.Y.K., Fok M., Wei W.I., Lam L.K., Tung P.H.M., Chu K.M., Wong J., Thoracoscopic esophageal mobilization for pharyngolaryngoesophagectomy, Annals of Thoracic Surgery. 2000, 70: 418-422.


Researcher : Fu M
List of Research Outputs

Fu M., Lui V.C.H., Cheung A.N.Y., Sham M.H., Tam P.K.H., Expression of homeobox gene HoxB5 is localized in the ganglia of human fetal and infant guts but not in Hirschsprung's disease gut, The XLVII Annual International Conference of the British Association of Paediatric Surgenos, London, U.K.. 2001.
Sham M.H., Lui V.C.H., Chen B.L.S., Fu M., Tam P.K.H., Novel mutations of SOX10 suggest a dominant negative role in Waardenburg-Shah syndrome, Journal of Medical Genetics. 2001, 38(9): E30.
Sham M.H., Lui V.C.H., Fu M., Chen B.L.S., Tam P.K.H., SOX10 is abnormally expressed in aganglionic bowel of Hirschsprung's disease infants, Gut. 2001, 49(2): 220-226.


Researcher : Ge Z
List of Research Outputs

Ge Z., Endothelium-dependent hyperpolarization and relaxation of coronary circulation during cardioplegic arrest of the heart, Thesis, Doctor of Philosophy, The University of Hong Kong. 2000.


Researcher : Goldschmidt EWM
List of Research Outputs

Goldschmidt E.W.M., Lam C.S.Y., Opper S., The development of myopia in Hong Kong children, Acta Ophthalmologica Scandinavica. 2001, 79: 228-232.


Researcher : Guo WH
List of Research Outputs

Chan K.L., Guo W.H., Chan K.W., Tam P.K.H., FR167653 ameliorates intestinal allograft ischemia injury, Transplantation Proceedings. 2000, 32: 1643-1644.
Chan K.L., Guo W.H., Tam P.K.H., Technical refinements for successful small bowel transplantation in pig, Transplantation Proceedings. 2000, 32: 2488-2489.
Guo W.H., Tian L., Dallmam M., Tam P.K.H., Heterotoic versus orthotopic small bowel transplantation: survival and immunological differences, 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, April 4-8, 2001.
Guo W.H., Chan K.L., Fung P.C.W., Chan K.W., Tam P.K.H., Nitric oxide protects segmental intestinal grafts from ischaemia and reperfusion I/R injury, Transplantation Proceedings. 2000, 32: 1297-1298.
Guo W.H., Tian L., Yuen Z.W., Chan K.L., Wo J.Y.H., Nicholls G., Dallman M., Tam P.K.H., Recipient FK506 pretreatment regimens in rat small bowel transplantation: allograft survival, function, and systemic infection, Journal of Pediatric Surgery. 2000, 35: 1600-1605.
Guo W.H., Tian L., Chan K.L., Dallman M., Tam P.K.H., Role of CD4+ and CD8+ T cells in early and late acute rejection of small bowel allograft, Journal of Pediatric Surgery. 2001, 36(2): 352-356.
Guo W.H., Tian L., Chan K.L., Tam P.K.H., Role of activated helper and cytotoxic T cells in early and late rejection of small bowel allograft, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Guo W.H., Tian L., Tam P.K.H., The production of a novel immunosuppressive fusion protein CTLA4-Ig and a study of its immunosuppressive function, 7th Hong Kong International Cancer Congress. 5th Research Postgraduate Symposium, Hong Kong, December 7-9, 2000.


Researcher : Ho CM
List of Research Outputs

Yuen P.W., Wei W.I., Lam K.Y., Ho C.M., Chow T.L., Yuen Y.F., A comparison of the prognostic significance of tumor diameter, length, width, thickness, area, volume, and clinicopathological features of oral tongue carcinoma, American Journal of Surgery. 2000, 80: 139-143.


Researcher : Ho JWC
Project Title:A case-control study on environmental and familial risk factors for colorectal cancer in Hong Kong
Investigator(s):Dr. Ho J.W.C. , Prof. Lam T.H., Dr. Yuen S.T.
Department:Surgery
Source(s) of Funding:Health Services Research Fund
Start Date:October 1997
Abstract:
To identify hereditary and acquired risk and protective factors for colorectal cancer in Hong Kong so that: 1) appropriate health measures can devised to prevent disease development; 2) individuals at high risk of developing colorectal cancer can be identified and preventive health measures and screening programmes can be targeted to this high risk group.


Project Title:The Hereditary Gastrointestinal Cancer Registry - a programme for the people of Hong Kong
Investigator(s):Dr. Ho J.W.C. , Dr. Chung L.P., Ms Kwan K.Y.M., Dr. Yuen S.T.
Department:Surgery
Source(s) of Funding:Terry Fox Fellowship granted by the Hong Kong Cancer Fund
Start Date:June 2000
Abstract:
To achieve colorectal cancer prevention in high risk families through early detection and timely treatment; to raise awareness of hereditary colorectal cancer through education of the public and the health care profession so as to ensure proper referral of these families to our Registry for the delivery of proper preventive service; to establish support services to improve psychosocial well beings of affected individuals and their at-risk family members; to improve the understanding of hereditary colorectal cancer and its management.


List of Research Outputs

Chan R.T.T., Au G.K.H., Ho J.W.C., Chu K.W., Radiation recall with oxaliplatin: report of a case and a review of the literature, Clinical Oncology. 2001, 13: 55-57.
Chan T.L., Yuen S.T., Ho J.W.C., Chan A.S.Y., Kwan K.Y.M., Chung L.P., Lam P.W.Y., Tse C.W., Leung S.Y., A novel germline 1.8-kb deletion of hMLH1 mimicking alternative splicing: a founder mutation in the Chinese population, Oncogene. 2001, 20: 2976-2981.
Chan T.L., Curtis L.C., Leung S.Y., Farrington S.M., Ho J.W.C., Chan A.S.Y., Lam P.W.Y., Tse C.W., Dunlop M.G., Wyllie A.H., Yuen S.T., Early-onset colorectal cancer with stable microsatellite DNA and near-diploid chromosomes, Oncogene. 2001, 20: 4871-4876.
Ho J.W.C., Lam W.W.M., Ooi C.G.C., Tsang K.W.T., Wong M.P., Chemoradiotherapy in advanced lymphoepitheliom-like carcinoma (LELC) of lung, Lung Cancer (Suppl). 2000, 29: 76-77.
Ho J.W.C., Yuen S.T., Chung L.P., Kwan K.Y.M., Chan T.L., Leung S.Y., Chan A.S.Y., Tse C.W., Lam P.W.Y., Luk S.C., Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients, International Journal of Cancer. 2000, 89: 356-360.
Law W.L., Chu K.W., Ho J.W.C., Tung H.M., Law S.Y.K., Chu K.M., Self-expanding metallic stent in the treatment of colonic obstruction due to advanced malignancies, Diseases of Colon and Rectum. 2000, 43: 1522-1527.
Leung S.Y., Yuen S.T., Chan T.L., Chan A.S.Y., Ho J.W.C., Kwan K.Y.M., Fan Y.W., Hung K.N., Chung L.P., Wyllie A.H., Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation, Oncogene. 2000, 19: 4079-4083.


Researcher : Ho WK
Project Title:Double blind randomized study to compare the efficacy and tolerability of 4 week's course of azelastine HCL nasal spray with oral loratadine in patients with perenial non-allergic rhimitis
Investigator(s):Dr. Ho W.K. , Dr. Yuen P.W.
Department:Surgery
Source(s) of Funding:Asta Medica Ag, Asta Medica China Ltd.
Start Date:February 1998
Abstract:
To assess the efficacy of a topical antihistamine.


Project Title:Study on the safety and efficacy of a new method with low morbidity to relieve nasal blockage - radiofrequency ablation of the inferior turbinates
Investigator(s):Dr. Ho W.K. , Dr. Yuen P.W.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:November 2000
Abstract:
To assess the efficacy and safety of radiofrequency (RFTA) volumetric reduction of the inferior turbinates of the nose as a less invasive method under local anesthesia to relieve the symptom of nasal blockage in these patients.


List of Research Outputs

Chow V.W.H., Yuen P.W., Lam K.Y., Tsao G.S.W., Ho W.K., Wei W.I., A comparative study of the clinicopathological significance of E-cadherin and catenins (a, b, g) expression in the surgical management of oral tongue carcinoma, Journal of Cancer Research and Clinical Oncology. 2001, 127: 59-63.
Chow V.W.H., Yuen P.W., Lam B.K.Y., Ho W.K., Wei W.I., Prognostic significance of serum p53 protein and p53 antibody in patients with surgical treatment for head and neck squamous cell carcinoma, Head & Neck. 2001, 23: 286-291.
Ho W.K., Hui Y., Wei W.I., Au D.K.K., Correlation of pure tone audiogram result and hearing benefit of tympanoplasty for chronic suppurative otitis media, Annals of Otology, Rhinology and Laryngology. 2000, 109: 381-384.
Ho W.K., Wei W.I., Yuen P.W., Hui Y., Effect of the external nasal dilator on nasal minimal cross-sectional area in Orientals as assessed by acoustic rhinometry, Otolaryngology. 2000, 29(6): 367-370.
Hui Y., Ma K.M., Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Chow C.M., The relationship between the size of neopharynx after laryngectomy and long term swallowing function - an assessment by scintigraphy, Otolaryngology - Head and Neck Surgery. 2001, 124: 225-9.
Law C.M., Ho W.K., Radiofrequency surgery in ENT, Departmental Journal Review. 2000.
Li G.K.H., Wei W.I., Lam L.K., Cheng A.K.K., Ho W.K., Yuen P.W., Sham J.S.T., Management of extensive cervical nodal metastasis in nasopharyngeal carcinoma after radiotherapy - a clinicopathologic study, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Qu J.N.Y., Yuen P.W., Ho W.K., Sham J., Wei W.I., Kwong D., Fluorescent endoscopy of nasopharyngeal carcinoma - preliminary study, Lasers of Surgery and Medicine. 2000, 26(5): 432-440.
Wei W.I., Wong R., Hui Y., Au D.K.K., Wong Y.K., Ho W.K., Tsang A., Kung P., Chung E., Chinese tonal language rehabilitation following cochlear implantation in children, Acta Oto-laryngologica (Stockh). 2000, 120: 218-221.
Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Wong L.Y., Quality of life in early postoperative period after major resection for head and neck cancer - a prospective study, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Yuen P.W., Lam K.Y., Choy J.T.H., Ho W.K., Wei W.I., Bcl-2 expression of laryngeal carcinoma, Clinical Otolaryngology and Allied Sciences. 2001, 26(2): 129-33.
Yuen P.W., Lam K.Y., Choy T.H., Ho W.K., Wei W.I., Clinicopathological significance of p53 and p21 expression in the surgical treatment of laryngeal carcinoma, Anticancer Research. 2000, 20: 4863-4866.


Researcher : Hu X
List of Research Outputs

Hu X., Chow L.W.C., Detection of circulating breast cancer cells with multiple-marker RT-PCR assay, Anticancer Research. 2001, 21: 421-424.
Hu X., Chow L.W.C., Fine needle aspiration may shed breast cells into peripheral blood as determined by RT-PCR, Oncology. 2000, 59(3): 217-222.
Hu X., Chow L.W.C., Review - Detection of circulating breast cancer cells by reverse transcriptase-polymerase chain reaction (RT-PCR), European Journal of Surgical Oncology. 2000, 26: 530-535.


Researcher : Hui Y
List of Research Outputs

Au D.K.K., Hui Y., Wong Y.K., Comparison of the results of two different implant systems using continuous interleaved sampler speech processing strategy, Advances in Otorhinolaryngology. 2000, 57: 430-434.
Ho W.K., Hui Y., Wei W.I., Au D.K.K., Correlation of pure tone audiogram result and hearing benefit of tympanoplasty for chronic suppurative otitis media, Annals of Otology, Rhinology and Laryngology. 2000, 109: 381-384.
Ho W.K., Wei W.I., Yuen P.W., Hui Y., Effect of the external nasal dilator on nasal minimal cross-sectional area in Orientals as assessed by acoustic rhinometry, Otolaryngology. 2000, 29(6): 367-370.
Hui Y., Ma K.M., Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Chow C.M., The relationship between the size of neopharynx after laryngectomy and long term swallowing function - an assessment by scintigraphy, Otolaryngology - Head and Neck Surgery. 2001, 124: 225-9.
Lam L.K., Hui Y., Ng W.M., Chung H.P., Li K.H., A new method of revision of peri-tracheostomal scar together with closure of tracheo-cutaneous fistula, 7th International Congress of Oriental Aesthetic Plastic Surgery, Seoul, Korea, October 2000.
Wei W.I., Wong R., Hui Y., Au D.K.K., Wong Y.K., Ho W.K., Tsang A., Kung P., Chung E., Chinese tonal language rehabilitation following cochlear implantation in children, Acta Oto-laryngologica (Stockh). 2000, 120: 218-221.
Wong R.K., Chung E., Hui Y., Wong B., Wei W.I., Speech perception and production performance of prelingually deafened adolescents after cochlear implantation, Updates in Cochlear Implantation. Advanced Otorhinolaryngology. 2000, 57: 373-376.
Wong Y.K., Hui Y., Au D.K.K., Wei W.I., Economic evaluation of cochlear implantation, Advances in Otorhinolaryngology. 2000, 57: 377-381.


Researcher : Hung KN
List of Research Outputs

Leung S.Y., Yuen S.T., Chan T.L., Chan A.S.Y., Ho J.W.C., Kwan K.Y.M., Fan Y.W., Hung K.N., Chung L.P., Wyllie A.H., Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation, Oncogene. 2000, 19: 4079-4083.
Tsang K.L., Hung K.N., Ho S.L., Subthalamic nucleus deep brain stimulation in idiopathic Parkinson's disease; a regional hospital experience in Hong Kong, 4th International Congress of Parkinson's Disease.. Helsinki, Finland., 2001.


Researcher : Kwan KYM
List of Research Outputs

Chan T.L., Yuen S.T., Ho J.W.C., Chan A.S.Y., Kwan K.Y.M., Chung L.P., Lam P.W.Y., Tse C.W., Leung S.Y., A novel germline 1.8-kb deletion of hMLH1 mimicking alternative splicing: a founder mutation in the Chinese population, Oncogene. 2001, 20: 2976-2981.
Ho J.W.C., Yuen S.T., Chung L.P., Kwan K.Y.M., Chan T.L., Leung S.Y., Chan A.S.Y., Tse C.W., Lam P.W.Y., Luk S.C., Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients, International Journal of Cancer. 2000, 89: 356-360.
Leung S.Y., Yuen S.T., Chan T.L., Chan A.S.Y., Ho J.W.C., Kwan K.Y.M., Fan Y.W., Hung K.N., Chung L.P., Wyllie A.H., Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation, Oncogene. 2000, 19: 4079-4083.


Researcher : Lai ECS
List of Research Outputs

Poon R.T.P., Ng I.O.L., Fan S.T., Lai E.C.S., Lo C.M., Liu C.L., Wong J., Clinicopathologic features of long-term survivors and disease-free survivors after resection of hepatocellular carcinoma: a study of a prospective cohort, Journal of Clinical Oncology. 2001, 19(12): 3037-3044.


Researcher : Lam BKY
List of Research Outputs

Chow V.W.H., Yuen P.W., Lam B.K.Y., Ho W.K., Wei W.I., Prognostic significance of serum p53 protein and p53 antibody in patients with surgical treatment for head and neck squamous cell carcinoma, Head & Neck. 2001, 23: 286-291.
Poon R.T.P., Fan S.T., Yu W.C., Lam B.K.Y., Chan F.Y.S., Wong J., A prospective longitudinal study of quality of life after resection of hepatocellular carcinoma, Archives of Surgery. 2001, 136: 693-699.


Researcher : Lam CM
List of Research Outputs

Chan A.O.O., Lam S.K., Chu K.M., Lam C.M., Kwok E.N.L., Leung S.Y., Yuen S.T., Law S.Y., Hui W.M., Lai K.C., Wong B.C.Y., Hu W.C.H., Lai C.L., Wong J., Soluble E-cadherin is a valid prognostic marker in gastric carcinoma., Gut. 2001, 48(6): 808-811.
Chan A.O.O., Lam S.K., Chu K.M., Lam C.M., Kwok E., Leung S.Y., Yuen S.T., Law S.Y.K., Hui W.M., Lai C.L., Wong C.Y., Hu H.C., Lai C.L., Wong J., Soluble E-cadherin is a valid prognostic marker in gastric carcinoma, Gut. 2001, 48: 808-811.
Poon R.T.P., Liu C.L., Lo C.M., Lam C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy, Archives of Surgery. 2001, 136: 11-16.


Researcher : Lam LK
List of Research Outputs

Chan H.H.L., Lam L.K., Wong D.S., Leung R.S., Ying S.Y., Lai C.F., Ho W.S., Chua J.K., Nevus of Ota: a new classification based upon the response to laser treatment, Lasers of Surgery and Medicine. 2001, 28: 267-72.
Hui Y., Ma K.M., Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Chow C.M., The relationship between the size of neopharynx after laryngectomy and long term swallowing function - an assessment by scintigraphy, Otolaryngology - Head and Neck Surgery. 2001, 124: 225-9.
Lam K.Y., Wei W.I., Ng K.W., Lam L.K., Law S.Y.K., Yuen P.W., Wong J., Pharyngolaryngo-oesophagectomy with pharyngogastric anastomosis - a meta analysis, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Lam L.K., Hui Y., Ng W.M., Chung H.P., Li K.H., A new method of revision of peri-tracheostomal scar together with closure of tracheo-cutaneous fistula, 7th International Congress of Oriental Aesthetic Plastic Surgery, Seoul, Korea, October 2000.
Lam L.K., Breast reconstruction, In: Li S.L. (ed), The Oncology of Breast Diseases. Scientific and Technical Documents Publishing House, 2000, 665-675.
Lam L.K., Honorary Secretary, Hong Kong Head and Neck Society, 2001.
Lam L.K., Honorary Treasurer, Hong Kong Society of Plastic and Reconstructive Surgeons, 2001.
Lam L.K., Wei W.I., Wong S.Y., Yuen P.W., Li K.H., Improved management of the donor site of free radial forearm flap, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Lam L.K., Member of Editorial Board, Chinese Journal of Burns, 2001.
Lam L.K., President, Hong Kong Burns Society, 2001.
Law S.Y.K., Fok M., Wei W.I., Lam L.K., Tung P.H.M., Chu K.M., Wong J., Thoracoscopic esophageal mobilization for pharyngolaryngoesophagectomy, Annals of Thoracic Surgery. 2000, 70: 418-422.
Li G.K.H., Wei W.I., Lam L.K., Cheng A.K.K., Ho W.K., Yuen P.W., Sham J.S.T., Management of extensive cervical nodal metastasis in nasopharyngeal carcinoma after radiotherapy - a clinicopathologic study, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Wong L.Y., Quality of life in early postoperative period after major resection for head and neck cancer - a prospective study, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Wong S.Y., Chan S.H., Lam L.K., Ng W.M., Li K.H., Chung H.P., Aesthetic considerations in the surgical management of Madelung's disease, 7th International Congress of Oriental Aesthetic Plastic Surgery, Seoul, Korea, October 2000.


Researcher : Lau H
List of Research Outputs

Chan Y.W., Lau H., Patil N.G., Lee F.C.W., Para-umbilical hernia: outcome comparison between emergency and elective repairs, Hong Kong Academy of Medicine Second International Congress. Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.
Lau H., Patil N.G., Lee F.C.W., Yuen W.K., A prospective trial of analgesia following endoscopic extraperitoneal inguinal hernioplasty: local wound infiltration versus extraperitoneal instillation of bupivacaine (Abstract), Surgical Endoscopy. 2001, 15 (Suppl.): S142.
Lau H., Patil N.G., Lee F.C.W., Yuen W.K., A prospective trial of analgesia following endoscopic extraperitoneal inguinal hernioplasty: local wound infiltration versus extraperitoneal instillation of bupivacaine, 2001 Annual Meeting, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Missouri, USA, April 18-21, 2001.
Lau H., Advances in vascular and minimal access surgery, Hospital Authority Annual Sharing Forum 2001, Hong Kong, April 7, 2001.
Lau H., Brooks D.C., Ambulatory laparoscopic cholecystectomy: the wave of the future (Abstract), Annals of the College of Surgeons of Hong Kong. 2001, 5: A18.
Lau H., Brooks D.C., Ambulatory laparoscopic cholecystectomy: the wave of the future, Towards Surgical Excellence, 8th Annual Scientific Meeting, The College of Surgeons of Hong Kong, Hong Kong, April 7, 2001.
Lau H., Cheng S.W.K., Axillofemoral bypass for limb salvage, Annals of the College of Surgeons of Hong Kong. 2000, 4: 149-153.
Lau H., Cheng S.W.K., Lam K.Y., Carotid artery aneurysm secondary to cystic medial necrosis, Journal of Royal College of Surgeons of Edinburgh. 2001, 46: 173-175.
Lau H., Chan Y.W., Lee F.C.W., Patil N.G., Clinical factors influencing pain level after ambulatory inguinal herniorrhaphy: a multivariate analysis, Hong Kong Academy of Medicine Second International Congress, Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.
Lau H., Lee F.C.W., Poon J., Clinical factors influencing return to work after ambulatory inguinal herniorrhaphy, Ambulatory Surgery. 2001, 9(1): 25-28.
Lau H., Lee F.C.W., Determinant factors of pain after ambulatory inguinal herniorrhaphy: a multi-variate analysis, Hernia. 2001, 5: 17-20.
Lau H., Dysphagia aortica: Harbinger of aortoesophageal fistula?, Surgery. 2001, 129(6): 763-764.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Early outcomes of laparoscopic totally extraperitoneal hernia repair versus open mesh hernioplasty, Asian Journal of Surgery. 2000, 23: 244-248.
Lau H., Cheng S.W.K., Is the preferential use of ePTFE grafts in femorofemoral bypass justified?, Annals of Vascular Surgery. 2001, 15(3): 383-387.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Laparoscopic totally extraperitoneal inguinal hernioplasty: results of 100 consecutive repairs, Annals of Academy of Medicine, Singapore. 2000, 29: 640-643.
Lau H., Cheng S.W.K., Long-term outcome of aortofemoral bypass for aortoiliac occlusive disease, Annals of Academy of Medicine, Singapore. 2000, 29: 434-438.
Lau H., Cheng S.W.K., Long-term prognosis of femoropopliteal bypass: an analysis of 349 consecutive revascularizations, The Australian and New Zealand Journal of Surgery. 2001, 71: 335-340.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Technique for safe placement of re-usable trocars during endoscopic extraperitoneal inguinal hernioplasty, Annals of the College of Surgeons of Hong Kong. 2000, 4: 123-126.
Ng K.C., Lau H., Patil N.G., Lee F.C.W., Epidemiology of hernia in adults, Hong Kong Academy of Medicine Second International Congress, Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.


Researcher : Law SYK
List of Research Outputs

Chan A.O.O., Lam S.K., Chu K.M., Lam C.M., Kwok E., Leung S.Y., Yuen S.T., Law S.Y.K., Hui W.M., Lai C.L., Wong C.Y., Hu H.C., Lai C.L., Wong J., Soluble E-cadherin is a valid prognostic marker in gastric carcinoma, Gut. 2001, 48: 808-811.
Chik B., Law S.Y.K., Photodynamic therapy for carcinoma of esophagus, Departmental Journal Review. 2001.
Chow V.W.H., Law S.Y.K., Lam K.Y., Luk J.M.C., Wong J., Telomerase activity in small cell esophageal carcinoma, Diseases of the Esophagus. 2001, 14: 139-142.
Chu K.M., Kwok K.F., Law S.Y.K., Wong J., One-week once-daily triple therapy for Helicobacter pylori - a pilot study, Hepatogastroenterology. 2000, 47: 1624-1626.
Law S.Y.K., Wong J., A positive oesophageal margin in stomach cancer, The Australian and New Zealand Journal of Surgery. 2000, 70: 697-698.
Law S.Y.K., Endoscopic management of dysphagia, Head and Neck Course 2001, Advanced Techniques, The University of Hong Kong, Queen Mary Hospital, Hong Kong. 2001, 45-46.
Law S.Y.K., Esophageal neoplasm, CD ROM of 4th Postgraduate Course: A Comprehensive Approach in the Management of Esophageal Diseases, St. Luke's Medical Center, Manila Philippines. 2000.
Law S.Y.K., Wong J., Esophogeal cancer, Current Opinion in Gastroenterology. 2001, 17: 393-399.
Law S.Y.K., Palliation for esophageal cancer (Abstract), 7th Joint Hong Kong-Shanghai Surgical Convention, Shanghai, China, January 2001.
Law S.Y.K., Surgical techniques in resection and reconstruction of esophageal diseases, 4th Postgraduate Course: A Comprehensive Approach in the Management of Esophageal Diseases, St. Luke's Medical Center, Manila, Philippines. 2000.
Law S.Y.K., Surgical treatment of neuromuscular diseases of the esophagus, CD ROM of 4th Postgraduate Course: A Comprehensive Approach in the Management of Esophageal Diseases, St. Luke's Medical Center, Manila, Philippines. 2000.
Law S.Y.K., Technical modifications in pharyngo-laryngo-esophagectomy, Course Manual and CD ROM: Head and Neck Course 2001, Advanced Techniques, University of Hong Kong, Queen Mary Hospital, Hong Kong. 2001, 25-26.
Law S.Y.K., Fok M., Wei W.I., Lam L.K., Tung P.H.M., Chu K.M., Wong J., Thoracoscopic esophageal mobilization for pharyngolaryngoesophagectomy, Annals of Thoracic Surgery. 2000, 70: 418-422.
Law S.Y.K., Wong J., Tumours of the oesophagus, In: Tjandra J.J., Clunie G.J.A. and Thomas R.J.S. (eds.), Textbook of Surgery. Australia, Blackwell Science, 2001, 2nd edition: Chapter 14, 103-111.
Law S.Y.K., Wong J., Two-field dissection is enough for esophageal cancer, Diseases of the Esophagus. 2001, 14: 98-103.
Law S.Y.K., Wong J., What is appropriate treatment for carcinoma of the thoracic esophagus?, World Journal of Surgery. 2001, 25: 189-195.
Law W.L., Chu K.W., Ho J.W.C., Tung H.M., Law S.Y.K., Chu K.M., Self-expanding metallic stent in the treatment of colonic obstruction due to advanced malignancies, Diseases of Colon and Rectum. 2000, 43: 1522-1527.
Lee Y.M., Law S.Y.K., Chu K.M., Wong J., Pyloroplasty in gastric replacement of the esophagus after esophagectomy: one-layer or two-layer technique?, Diseases of the Esophagus. 2000, 13: 203-206.
Tang C.O., Lam A.K.Y., Law S.Y.K., Wong J., Srivastava G., Detection of genetic alterations in esophageal squamous cell carcinomas and adjacent normal epithelia by comparative DNA fingerprinting using inter-simple sequence repeat PCR1, Clinical Cancer Research. 2001, 7: 1539-1545.
Tang C.O., Wan T.S.K., Wong N., Pang E., Lam A.K.Y., Law S.Y.K., Chow L.M.C., Ma E.S.K., Chan L.C., Wong J., Srivastava G., Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin, Cancer Genetics and Cytogenetics. 2001, 124(1): 36-41.
Tang C.O., Wan T.S.K., Wong N., Pang E., Lam A.K.Y., Law S.Y.K., Chow L.M.C., Ma E.S.K., Chan L.C., Wong J., Srivastava G., Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin, Proceedings at the 7th Hong Kong International Cancer Congress, Hong Kong, 7-9 December. 2000.
Tang J.C.O., Lam K.Y., Law S.Y.K., Wong J., Srivastava G., Detection of genetic alterations in esophageal squamous cell carcinoma tumor specimens and adjacent normal epithelia by comparative DNA fingerprinting using inter-simple sequence repeat PCR (Abstract), 7th Hong Kong International Cancer Congress, 5th Research Postgraduate Symposium, December 2000.
Tang J.C.O., Lam A.K.Y., Law S.Y.K., Wong J., Srivastava G., Detection of genetic alterations in esophageal squamous cell carcinomas and adjacent normal epithelia by comparative DNA fingerprinting using inter-simple sequence repeat PCR, Proceedings at the 7th Hong Kong International Cancer Congress, Hong Kong, 7-9 December. 2000.
Tang J.C.O., Wan T.S.K., Wong N., Pang E., Lam K.Y., Law S.Y.K., Chow L.M.C., Ma E.S.K., Chan L.C., Wong J., Srivastava G., Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin (Abstract), 7th Hong Kong International Cancer Congress, 5th Research Postgraduate Symposium, December 2000.
Tung P.H.M., Law S.Y.K., Chu K.M., Law W.L., Wong J., Gastric rupture after Heimlich manoeuver and cardiopulmonary resuscitation, Hepato-Gastroenterology. 2001, 48: 109-111.
Whooley B.P., Law S.Y.K., Murthy S.C., Alexandrou A., Wong J., Analysis of reduced death and complication rates after esophageal resection, Annals of Surgery. 2001, 233: 338-344.
Whooley B.P., Law S.Y.K., Alexandrou A., Murthy S.C., Wong J., Critical appraisal of the significance of intrathoracic anastomotic leakage after esophagectomy for cancer, The American Journal of Surgery. 2001, 181: 198-203.
Wong J., Law S.Y.K., Esophageal resection in the new millennium. Does minimally invasive surgery play a role?, Syllabus for SSAT Post-graduate Course, DDW 2000. 2000.
Wong J., Law S.Y.K., Esophagogastrectomy for carcinoma of the esophagus and gastric cardia, and the esophageal anastomosis, In: Baker R.J. and Fischer J.E. (eds.), Mastery of Surgery. Philadelphia, USA, Lippincott Williams & Wilkins, 2001, 4th edition: Chapter 64, 813-827.
Wong J., Law S.Y.K., Reconstruction techniques in cancer of the gastroesophageal junction (Invited Lecture), 4th International Gastric Cancer Congress, New York, 2001. S06.
Wong J., Law S.Y.K., Transhiatal esophagectomy - Esophagectomy without thoracotomy, In: Baker R.J. and Fischer J.E. (eds.), Mastery of Surgery. Philadelphia, USA, Lippincott Williams & Wilkins, 2001, 4th edition: Chapter 65, 828-836.


Researcher : Law WL
List of Research Outputs

Chu K.W., Law W.L., Recurrence after rectal cancer operation, Chinese Journal of Gastrointestinal Surgery. 2000, 3: 209-212.
Day W., Law W.L., Pseudo-obstruction of colon, Departmental Journal Review. 2000.
Law W.L., Chu K.W., Ho J.W.C., Tung H.M., Law S.Y.K., Chu K.M., Self-expanding metallic stent in the treatment of colonic obstruction due to advanced malignancies, Diseases of Colon and Rectum. 2000, 43: 1522-1527.
Lee Y.M., Law W.L., Chu K.W., Abdominal actinomycosis: report of 3 cases, The Australian and New Zealand Journal of Surgery. 2001, 71: 261-263.
Lee Y.M., Law W.L., Chu K.W., Poon R.T.P., Emergency surgery for obstructing colorectal cancers: a comparison between right-sided and left-sided lesions, Journal of American College of Surgery. 2001, 192: 719-725.
Tsu J., Law W.L., Stapled haemorrhoidectomy, Departmental Journal Review. 2001.
Tung P.H.M., Law S.Y.K., Chu K.M., Law W.L., Wong J., Gastric rupture after Heimlich manoeuver and cardiopulmonary resuscitation, Hepato-Gastroenterology. 2001, 48: 109-111.


Researcher : Lee FCW
List of Research Outputs

Chan Y.W., Lau H., Patil N.G., Lee F.C.W., Para-umbilical hernia: outcome comparison between emergency and elective repairs, Hong Kong Academy of Medicine Second International Congress. Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.
Cheung M.C., Leung S.Y.L., Wong B.B.W., Lee F.C.W., Tam P.C., Can ultrasonography (USG) plus plain radiograph replace intravenous urogram (IVU) in prediction of residual ureteric obstruction after primary in-situ extracorporeal shockwave lithotripsy (ESWL) for ureteric stone - a prospective study, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Cheung M.C., Lee F.C.W., Yip S.K.H., Tam P.C., Outpatient holmium laser lithotripsy using semirigid ureteroscope, European Urology. 2001, 39: 702-708.
Cheung M.C., Yip S.K.H., Lee F.C.W., Tam P.C., Outpatient ureteroscopic lithotripsy: selective internal stenting and factors enhancing success, Journal of Endourology. 2000, 14: 559-564.
Choi H.K., Chow L.W.C., Goh L.C., Tsui S.L., Lee F.C.W., The impact of postoperative nausea and vomiting on the practice of day surgery for Chinese women with breast diseases, Ambulatory Surgery. 2001, 9: 29-32.
Fan K.M., Lee F.C.W., Ureteric obstruction: effects on renal function, Departmental Journal Review. 2001.
Ho K.L., Leung S.Y.L., Cheung M.C., Wong B.B.W., Chu S.S.M., Lee F.C.W., Tam P.C., An audit of urological day surgery service - a 5-year experience in the Day Surgery Centre in Tung Wah Hospital, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Lau H., Patil N.G., Lee F.C.W., Yuen W.K., A prospective trial of analgesia following endoscopic extraperitoneal inguinal hernioplasty: local wound infiltration versus extraperitoneal instillation of bupivacaine (Abstract), Surgical Endoscopy. 2001, 15 (Suppl.): S142.
Lau H., Patil N.G., Lee F.C.W., Yuen W.K., A prospective trial of analgesia following endoscopic extraperitoneal inguinal hernioplasty: local wound infiltration versus extraperitoneal instillation of bupivacaine, 2001 Annual Meeting, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Missouri, USA, April 18-21, 2001.
Lau H., Chan Y.W., Lee F.C.W., Patil N.G., Clinical factors influencing pain level after ambulatory inguinal herniorrhaphy: a multivariate analysis, Hong Kong Academy of Medicine Second International Congress, Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.
Lau H., Lee F.C.W., Poon J., Clinical factors influencing return to work after ambulatory inguinal herniorrhaphy, Ambulatory Surgery. 2001, 9(1): 25-28.
Lau H., Lee F.C.W., Determinant factors of pain after ambulatory inguinal herniorrhaphy: a multi-variate analysis, Hernia. 2001, 5: 17-20.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Early outcomes of laparoscopic totally extraperitoneal hernia repair versus open mesh hernioplasty, Asian Journal of Surgery. 2000, 23: 244-248.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Laparoscopic totally extraperitoneal inguinal hernioplasty: results of 100 consecutive repairs, Annals of Academy of Medicine, Singapore. 2000, 29: 640-643.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Technique for safe placement of re-usable trocars during endoscopic extraperitoneal inguinal hernioplasty, Annals of the College of Surgeons of Hong Kong. 2000, 4: 123-126.
Leung S.Y.L., Cheung M.C., Wong B.B.W., Chu S.S.M., Lee F.C.W., Tam P.C., Same day transurethral resection - vaporization of the prostate (TURVP) for the treatment of benign prostatic hyperplasia, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Ng K.C., Lau H., Patil N.G., Lee F.C.W., Epidemiology of hernia in adults, Hong Kong Academy of Medicine Second International Congress, Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.
Wong B.B.W., Cheung M.C., Leung S.Y.L., Ho K.L., Chu S.S.M., Lee F.C.W., Tam P.C., The value of noncontrast helical computer tomography in the diagnosis of acute ureteric colic, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Yip K.H., Cheung M.C., Wong B.B.W., Lee F.C.W., Tam P.C., Outpatient ureteroscopic lithotripsy: selective internal stenting and factors enhancing success, 25th Congress of the Societe and Internationale d'Urologie, Singapore, October 29 - November 2, 2000.


Researcher : Lee KW
List of Research Outputs

Lee K.W., Han J.S., Fan S.T., Liang Z.D., Tian P.K., Gu J.R., Ng I.O.L., Gene delivery using a receptor-mediated gene transfer system targeted to hepatocellular carcinoma cells, International Journal of Cancer. 2001, 93: 393-400.


Researcher : Leung SYL
List of Research Outputs

Cheung M.C., Leung S.Y.L., Wong B.B.W., Lee F.C.W., Tam P.C., Can ultrasonography (USG) plus plain radiograph replace intravenous urogram (IVU) in prediction of residual ureteric obstruction after primary in-situ extracorporeal shockwave lithotripsy (ESWL) for ureteric stone - a prospective study, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Chok S.H., Leung S.Y.L., Chemotherapy in the management of hormone-refractory prostate cancer, Departmental Journal Review. 2001.
Ho K.L., Leung S.Y.L., Cheung M.C., Wong B.B.W., Chu S.S.M., Lee F.C.W., Tam P.C., An audit of urological day surgery service - a 5-year experience in the Day Surgery Centre in Tung Wah Hospital, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Leung S.Y.L., Cheung M.C., Wong B.B.W., Chu S.S.M., Lee F.C.W., Tam P.C., Same day transurethral resection - vaporization of the prostate (TURVP) for the treatment of benign prostatic hyperplasia, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Leung S.Y.L., Treatment of advanced prostate cancer beyond hormonal therapy, Thesis, Master of Surgery, The University of Hong Kong. 2000.
Wong B.B.W., Cheung M.C., Leung S.Y.L., Ho K.L., Chu S.S.M., Lee F.C.W., Tam P.C., The value of noncontrast helical computer tomography in the diagnosis of acute ureteric colic, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Yeung Y., Leung S.Y.L., A reappraisal on the management of renal trauma, Departmental Journal Review. 2000.


Researcher : Lin C
Project Title:The effect of tryptophan metabolism on the regulation of function and migration of dendritic cells
Investigator(s):Dr. Lin C.L. , Prof. Austyn J.M., Prof. Tam P.K.H.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:May 2001
Abstract:
To investigate the effects of an enzyme, indoleamine 2,3-dioxygenase (IDO) and its inhibitor on the regulation of functions and migration of human myeloid dendritic cells.


List of Research Outputs

Chen C.L., Chen Y.S., De Villa V.H., Wang C.C., Lin C., Goto S., Wang S.H., Cheng Y.F., Huang T.L., Jawan B., Cheung H.K., Minimal blood loss living donor hepatectomy, Transplantation. 2000, 69: 2580-2586.
Goto S., Lin Y.C., Lai C.Y., Lee C.M., Pan T.L., Lord R., Chiang K.C., Tseng H.P., Lin C., Cheng Y.F., Yokoyama H., Kitano S., Telomerase activity in rat liver allografts, Transplantation. 2000, 69: 1013-1015.
Lin C., Sewell A., Gao G.F., Whelan K., Philips R., Austyn J.M., M-tropic HIV-1 induces and modulates dendritis cell chemotaxis, Journal of Experience Medicine. 2000, 192: 587-594.
Pan T.L., Lin C., Chen C.L., Lin Y.C., Dojo S., Lee T.H., Wang Y.H., Lord R., Lai C.Y., Tsu L.W., Tseng H.P., Wu M.L., Iwashida Y., Kitano S., Chiang K.C., Hashimoto T., Sugioka A., Goto S., Identification of the indoleamine 2,3-dioxygenase nucleotide sequence in a rat liver transplantation model, Transplantation Immunology. 2000, 8: 189-194.


Researcher : Liu CL
List of Research Outputs

Au W.Y., Ma E.S.K., Kwong Y.L., Ng I.O.L., Hawkins B.R., Wan T.S.K., Liu C.L., Fan S.T., Lo C.M., Graft versus host disease after liver transplantation: documentation by FISH and HLA typing., Clinical Transplantation. 2000, 14: 173-176.
Lam B.K., Lo C.M., Fung A.S., Fan S.T., Liu C.L., Wong J., Marital adjustment after interspouse living donor liver transplantation, Transplantation Proceedings. 2000, 32: 2095-2096.
Li N., Kumana C.R., Cheung B.M.Y., Fan S.T., Liu C.L., Age affects blood pressure and heart rate following IV diazepam, VII World Conference on Clinical Pharmacology & Therapeutics 4th Congress of the European Association for Clinical Pharmacology & Therapeutics. 2001.
Liu C.L., Fan S.T., Acute cholangitis, In: Holzheimer R.G. and Mannick J.A., Surgical Treatment - Evidence Based and Problem-Oriented. New York, W Zuckschwerdt Verlag, 2001, 366-371.
Liu C.L., Fan S.T., Lo C.M., Poon R.T.P., Wong J., Anterior approach for major right hepatic resection for large hepatocellular carcinoma, Annals of Surgery. 2000, 232: 25-31.
Liu C.L., Lo C.M., Fan S.T., Endoscopic ultrasonography in pancreatitis (Review Article), Annals of the College of Surgeons of Hong Kong. 2000, 4: 145-148.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), American Journal of Transplantation. 2001, 1(Suppl 1): 261:A502.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis., Annas ofl Surgery. 2001, 233(2): 276-281.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis, Annals of Surgery. 2001, 233: 276-281.
Lo C.M., Fan S.T., Liu C.L., Lai C.L., Lau G.K.K., Yong B.H., Ng I.O.L., Young K., Chan J.C.K., Wong J., Liver transplantation in Hong Kong - a wider application., Transplantation Proceedings. 2000, 32(7): 2141.
Lo C.M., Fan S.T., Liu C.L., Lai C.L., Lau G.K.K., Yong B.H., Ng I.O.L., Young K., Chan J.K., Wong J., Liver transplantation in Hong Kong - a wider application, Transplantation Proceedings. 2000, 32: 2141.
Lo C.M., Fan S.T., Liu C.L., Ng I.O.L., Lam B.K., Yong B.H., Lai C.L., Lau G.K.K., Wong J., More effective immunosuppression with the use of FK506 after liver transplantation., Transplantation Proceedings. 2000, 32(7): 2269-2270.
Lo C.M., Fan S.T., Liu C.L., Ng I.O.L., Lam B.K., Yong B.H., Lai C.L., Lau G.K., Wong J., More effective immunosuppression with the use of FK506 after liver transplantation, Transplantation Proceedings. 2000, 32: 2269-2270.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 373:A944.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Ng I.O.L., Liu C.L., Fan S.T., Ng M., Expression of P-glycoprotein in hepatocellular carcinoma. A determinant of chemotherapy response, Anatomic Pathology. 2000, 113: 355-363.
Poon R.T.P., Ng I.O.L., Fan S.T., Lai E.C.S., Lo C.M., Liu C.L., Wong J., Clinicopathologic features of long-term survivors and disease-free survivors after resection of hepatocellular carcinoma: a study of a prospective cohort, Journal of Clinical Oncology. 2001, 19(12): 3037-3044.
Poon R.T.P., Fan S.T., Ng I.O.L., Lo C.M., Liu C.L., Wong J., Different risk factors and prognosis of early and late intrahepatic recurrence after resection of hepatocellular carcinoma, Cancer. 2000, 89: 500-507.
Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Ng I.O.L., Wong J., Long-term prognosis after resection of hepatocellular carcinoma associated with hepatitis B-related cirrhosis, Journal of Clinical Oncology. 2000, 18: 1094-1101.
Poon R.T.P., Liu C.L., Lo C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy (Abstract), Digestive Disease Week 2000, San Diego, U.S.A. 2000.
Poon R.T.P., Liu C.L., Lo C.M., Lam C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy, Archives of Surgery. 2001, 136: 11-16.
Yong B.H., Tsui S.L., Leung C.C., Lo C.M., Liu C.L., Fan S.T., Young K., Management of postoperative analgesia in living liver donors, Transplantation Proceedings. 2000, 32: 2110.


Researcher : Lo CM
Project Title:Effect of somatostatin on small-for-size grafts in rat liver transplantation
Investigator(s):Prof. Lo C.M.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1997
Abstract:
To test the hypothesis that somatostatin may improve the survival of small-for-size liver grafts by decreasing portal pressure and preventing excessive hepatic blood flow which may be the cause of hepatic microvascular damage.


List of Research Outputs

Au W.Y., Lo C.M., Hawkins B.R., Ma E.S.K., Lie A.K.W., Kwong Y.L., Evans' syndrome and chronic graft versus host disease after liver transplantation., Transplantation. 2001, 72: 527-528.
Au W.Y., Ma E.S.K., Kwong Y.L., Ng I.O.L., Hawkins B.R., Wan T.S.K., Liu C.L., Fan S.T., Lo C.M., Graft versus host disease after liver transplantation: documentation by FISH and HLA typing., Clinical Transplantation. 2000, 14: 173-176.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Liver transplantation is not contraindicated in infancy, Transplantation Proceedings. 2000, 32(7): 2142-2143.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Post liver transplantation stenosis of biliary-enteric anastomoses in infancy: diagnosis and treatment, Transplantation Proceedings. 2000, 32(7): 2233-2234.
De Villa V.H., Chen C.L., Chen Y.S., Wang C.C., Wang S.H., Chiang Y.C., Cheng Y.F., Huang T.L., Jawan B., Cheung H.K., Fan S.T., Lo C.M., International sharing of split liver grafts in Asia: initial experience, Clinical Transplantation. 2000, 14: 355-359.
Lam B.K., Lo C.M., Fung A.S., Fan S.T., Liu C.L., Wong J., Marital adjustment after interspouse living donor liver transplantation, Transplantation Proceedings. 2000, 32: 2095-2096.
Liu C.L., Fan S.T., Lo C.M., Poon R.T.P., Wong J., Anterior approach for major right hepatic resection for large hepatocellular carcinoma, Annals of Surgery. 2000, 232: 25-31.
Liu C.L., Lo C.M., Fan S.T., Endoscopic ultrasonography in pancreatitis (Review Article), Annals of the College of Surgeons of Hong Kong. 2000, 4: 145-148.
Lo C.M., A randomised controlled trial of transarterial lipiodol chemoembolisation for unresectable hepatocellular carcinoma, The Second Annual Scientific Meeting of Centre for the Study of Liver Diseases, The University of Hong Kong, Hong Kong, February 17-18, 2001.
Lo C.M., Adult-to-adult living donor liver transplantation, Liver Diseases in the New Millennium - Fourth Shanghai International Symposium on Liver Cancer and Hepatitis and the Second Scientific Meeting of Cheng Si-yuan (China International) Hepatitis Research Foundation, Pudong, Shanghai, China, September 23-26. 2000.
Lo C.M., Application of living donor liver transplantation to adult recipients, First Joint Xian/Hong Kong Surgical Convention, Xian, China, July 3-4, 2000.
Lo C.M., Chairman, Liver Transplantation, Liver Disease in the New Millennium - Fourth Shanghai International Symposium on Liver Cancer and Hepatitis and the Second Scientific Meeting of Cheng Si-yuan (China-International) Hepatitis Research Foundation, Pudong, Shanghai, China, September 23-26, 2000.
Lo C.M., Chairman, Second Annual Scientific Meeting of Centre for the Study of Liver Disease, The University of Hong Kong, February 17-18, 2001.
Lo C.M., Council Member (1995 - present), Hong Kong Society of Minimal Access Surgery, 2001.
Lo C.M., Course Faculty, Liver Transplantation: A Multidisciplinary Team Approach, Skills Development Centre, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, November 4, 2000.
Lo C.M., Editorial Board (1995 - present), Endoscopic and Laparoscopic Surgeons of Asia. 2001.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), American Journal of Transplantation. 2001, 1(Suppl 1): 261:A502.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Lo C.M., Fan S.T., Endocrine tumours of the pancreas, Annals of the College of Surgeons of Hong Kong. 2001, 5: 110-115.
Lo C.M., Examiner in Surgery, Licentiate Examination (May 1994 - present), The Licentiate Committee of the Medical Council of Hong Kong, 2001.
Lo C.M., Honorary Consultant (July 1, 1998 - present), Hospital Authority, Hong Kong, 2001.
Lo C.M., Honorary Secretary and Council Member (April 2001 - present), Hong Kong Society of Transplantation, 2001.
Lo C.M., Honorary Treasurer and Council Member (1999 - April 2001), Hong Kong Society of Transplantation, 2001.
Lo C.M., Fan S.T., Wong J., Intrahepatic stones, In: Morris P.J. and Wood W.C. (eds.) , Oxford Textbook of Surgery. New York, USA, Oxford University Press Inc., 2000, 2nd edition: 3357-3360.
Lo C.M., Liver transplant, Seminar on Organ Donation and Transplantation, Hospital Authority, Hong Kong, April 10,, 2001.
Lo C.M., Liver failure and liver transplant, Critical Care Course for Nurses, Hong Kong Sanatorium & Hospital, Hong Kong, November 30, 2000.
Lo C.M., Liver failure and liver transplant, Diploma in Intensive Care Nursing Course, School of Professional and Continuing Education, The University of Hong Kong, August 30, 2000. 2000.
Lo C.M., Liver resection without blood - a prerequisite for living donor liver transplant, The Sixth Annual Conference of the National Association for Bloodless Medicine and Surgery, Seattle, USA, September 15-16, 2000.
Lo C.M., Liver transplantation - a global overview - Hong Kong prospective, XXXII World Congress of International College of Surgeons, Singapore, October 8-12, 2000.
Lo C.M., Liver transplantation - surgical techniques, Liver Transplantation: A Multidisciplinary Team Approach, Skills Development Centre, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, November 4, 2000.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis., Annas ofl Surgery. 2001, 233(2): 276-281.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis, Annals of Surgery. 2001, 233: 276-281.
Lo C.M., Fan S.T., Liu C.L., Lai C.L., Lau G.K.K., Yong B.H., Ng I.O.L., Young K., Chan J.C.K., Wong J., Liver transplantation in Hong Kong - a wider application., Transplantation Proceedings. 2000, 32(7): 2141.
Lo C.M., Fan S.T., Liu C.L., Lai C.L., Lau G.K.K., Yong B.H., Ng I.O.L., Young K., Chan J.K., Wong J., Liver transplantation in Hong Kong - a wider application, Transplantation Proceedings. 2000, 32: 2141.
Lo C.M., Liver transplantation in Hong Kong, Liver Diseases in the New Millennium - Fourth Shanghai International Symposium on Liver Cancer and Hepatitis and the Second Scientific Meeting of Cheng Si-yuan (China-International) Hepatitis Research Foundation, Pudong, Shanghai, China, September 23-26, 2000.
Lo C.M., Liver transplantation in Hong Kong: problems and practice, Second China-Taiwan-Hong Kong Transplantation Meeting, Shanghai, China, October 17-19, 2000.
Lo C.M., Liver transplantation, Federation - Society Certificate Course for Health Professional, Hong Kong Society of Transplantation and the Federation of Medical Societies of Hong Kong, February 20, 2001.
Lo C.M., Liver transplantation, Post Registration Certificate Course in Perioperative Nursing, Hospital Authority, Hong Kong, May 26, 2001.
Lo C.M., Fan S.T., Living donor liver transplantation in adults, Graft. 2000, 3: 260-264.
Lo C.M., Fan S.T., Living donor liver transplantation: donor selection, evaluation, and surgical complications, Current Opinion in Organ Transplantation. 2001, 6: 120-125.
Lo C.M., Living donor liver transplantation: overview of experience of University of Hong Kong, Living Donor Liver Transplantation Symposium, Hong Kong, February 10, 2001.
Lo C.M., Living related transplant for the treatment of hepatobiliary malignancies, The 17th World Congress of the International Society of Digestive Surgery, Hamburg, Germany, September 6-9, 2000.
Lo C.M., Management of liver transplant, Critical Care Course for Nurses, Hong Kong, November 30, 2000.
Lo C.M., Member of Editorial Board, Journal of American Medical Association, South-East Asia, 2001.
Lo C.M., Member of Editorial Board, Journal of Endoscopic and Laparoscopic Surgeons of Asia (ELSA), 2001.
Lo C.M., Member, Program Committee (December 1997 - present), International Society for Digestive Surgery, 2001.
Lo C.M., Member, Quality Assurance Subcommittee in Surgery (1995 - March 2001), Hospital Authority, Hong Kong, 2001.
Lo C.M., Member, Scientific Committee (July 1998 - present), Cheng Si Yuan China - International Hepatitis Research Foundation, 2001.
Lo C.M., Moderator, Hepato-biliary Session: Functional Capacity of the Compensatory Hypertrophied Liver after Portal Vein Ligation in Rat-analysis OFN Expression Profiles using cDNA Microarray, 17th World Congress of the International Society for Digestive Surgery, Hamburg, Germany, September 6-9, 2000.
Lo C.M., Moderator, Hepatobiliary/Pancreas - Case Presentation, Hong Kong Surgical Forum, Hong Kong, July 1-2, 2000.
Lo C.M., Moderator, Liver Transplantation, Fourth Shanghai International Symposium on Liver Cancer and Hepatitis, Pudong, Shanghai, China, September 23-26, 2000.
Lo C.M., Fan S.T., Liu C.L., Ng I.O.L., Lam B.K., Yong B.H., Lai C.L., Lau G.K.K., Wong J., More effective immunosuppression with the use of FK506 after liver transplantation., Transplantation Proceedings. 2000, 32(7): 2269-2270.
Lo C.M., Fan S.T., Liu C.L., Ng I.O.L., Lam B.K., Yong B.H., Lai C.L., Lau G.K., Wong J., More effective immunosuppression with the use of FK506 after liver transplantation, Transplantation Proceedings. 2000, 32: 2269-2270.
Lo C.M., National Delegate (July 1998 - present), International Society for Digestive Surgery, 2001.
Lo C.M., Problems and practice with the development of liver transplantation at Queen Mary Hospital, The Hong Kong Medical Diary. 2001, 6: 16-17.
Lo C.M., Resection for hepatocellular carcinoma - how I do it?, XXXII World Congress of the International College of Surgeons, Singapore, October 8-12, 2000.
Lo C.M., Reviewer, UICC Fellowship (November 1997 - present), International Union Against Cancer, 2001.
Lo C.M., Reviewer, Asian Journal of Surgery, 2001.
Lo C.M., Reviewer, British Journal of Surgery, 2001.
Lo C.M., Reviewer, Annals of Surgery, 2001.
Lo C.M., Reviewer, Annals of The College of Surgeons of Hong Kong, 2001.
Lo C.M., Reviewer, Endoscopy, 2001.
Lo C.M., Reviewer, Hong Kong Medical Journal, 2001.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 373:A944.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Lo C.M., Fan S.T., Surgical techniques in right lobe liver transplantation, Transplantation Proceedings. 2000, 32: 1512-1513.
Lo C.M., The liver is not bloody (Abstract), Hong Kong Academy of Medicine Second International Congress, Hong Kong, November 2-5, 2000.
Lo C.M., Vice-President (September 2000 - present), International Society for Digestive Surgery, 2000.
Lo C.Y., Lo C.M., Fan S.T., Role of laparoscopic ultrasonography in intraoperative localization of pancreatic insulinoma, Surgical Endoscopy - Ultrasound and Interventional Techniques. 2000, 14: 1131-1135.
Man K., Fan S.T., Lo C.M., Wong J., Graft injury correlated with portal hemodynamics and intra graft endothelin-1 expression in living donor liver transplantaion in relation to graft size (Abstract), The Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Man K., Fan S.T., Lo C.M., Wong J., Graft injury correlated with portal hemodynamics and intra graft endothelin-1 expression in living donor liver transplantation in relation to graft size (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 369:A926.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L., Fan S.T., Wong J., Liver transplantation in rats using small-for-size grafts - a study of hemodynamic and morphological changes, Archives of Surgery. 2001, 136: 280-285.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L.F., Fan S.T., Wong J., The mechanism of small-for-size graft injury after liver transplantation, Fourth Shanghai International Symposium on Liver Cancer and Hepatitis and the Second Scientific Meeting of Cheng Si-Yuan (China International) Hepatitis Research Foundation, Pudong, Shanghai, China, September 23-26, 2000.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L.F., Fan S.T., Wong J., The mechanism of small-for-size graft injury after liver transplantation, Journal of Gastroenterology and Hepatology. 2000, 15: 1139 (O-L-7).
Ng I.O.L., Shek T.W.H., Thung S.N., Ye M.M.Q., Lo C.M., Fan S.T., Lee M.F., Chan K.W., Cheung A.N.Y., Microsatellite analysis in post-transplantation lymphoproliferative disorder to determine donor/recipient origin, Modern Pathology. 2000, 13(11): 1180-1185.
Poon R.T.P., Ng I.O.L., Fan S.T., Lai E.C.S., Lo C.M., Liu C.L., Wong J., Clinicopathologic features of long-term survivors and disease-free survivors after resection of hepatocellular carcinoma: a study of a prospective cohort, Journal of Clinical Oncology. 2001, 19(12): 3037-3044.
Poon R.T.P., Fan S.T., Ng I.O.L., Lo C.M., Liu C.L., Wong J., Different risk factors and prognosis of early and late intrahepatic recurrence after resection of hepatocellular carcinoma, Cancer. 2000, 89: 500-507.
Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Ng I.O.L., Wong J., Long-term prognosis after resection of hepatocellular carcinoma associated with hepatitis B-related cirrhosis, Journal of Clinical Oncology. 2000, 18: 1094-1101.
Poon R.T.P., Liu C.L., Lo C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy (Abstract), Digestive Disease Week 2000, San Diego, U.S.A. 2000.
Poon R.T.P., Liu C.L., Lo C.M., Lam C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy, Archives of Surgery. 2001, 136: 11-16.
Poon R.T.P., Ng I.O.L., Lau C., Zhu L.X., Yu W.C., Lo C.M., Fan S.T., Wong J., Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: a prospective study, Annals of Surgery. 2001, 233: 227-235.
Saing H., Fan S.T., Wei W.I., Chan K.L., Lo C.M., Mya G.H., Tsoi N.S., Yuen K.Y., Ng I.L.O., Chau M.T., Tso W.K., Chan J.F.K., Wong J., Pediatric liver transplantation: the Hong Kong experience, 6th Congress of the Cambodian Surgical Society, Cambodia, October 25-26, 2000.
Saing H., Fan S.T., Chan K.L., Wei W.I., Lo C.M., Mya G.H., Wong J., Portoenterostomy complimented by liver transplantation for biliary atresia: the Queen Mary Hospital, Hong Kong experience, 6th Congress of the Cambodian Surgical Society, October 25-26, 2000.
Yong B.H., Tsui S.L., Leung C.C., Lo C.M., Liu C.L., Fan S.T., Young K., Management of postoperative analgesia in living liver donors, Transplantation Proceedings. 2000, 32: 2110.


Researcher : Lo CY
List of Research Outputs

Chok S.H., Lo C.Y., Minimally invasive parathyroidectomy: another gold standard?, Departmental Journal Review. 2000.
Lam A.K.Y., Lo C.Y., A critical examination of adrenal tuberculosis and a 28-year autopsy experience of active tuberculosis, Clinical Endocrinology. 2001, 54: 633-639.
Lam A.K.Y., Lo C.Y., Wat N.M.S., Luk J.M.C., Lam K.S.L., The clinicopathological features and importance of p53, Rb, and mdm2 expression in phaeochromocytomas and paragangliomas, Journal of Clinical Pathology. 2001, 54(6): 443-448.
Lam K.Y., Lo C.Y., Lui M.C., Primary squamous cell carcinoma of thyroid gland: clinicopathologic experience p53 and cytokeratic experience, 12th International Thyroid Congress, October 22-29, 2000.
Lo C.Y., Council Member (1996 - present), Asian Association of Endocrine Surgeons, 2001.
Lo C.Y., Director, The Hong Kong Jockey Club Skills Development Centre (1997 - present), Department of Surgery, Queen Mary Hospital, 2001.
Lo C.Y., Fan S.T., Endocrine tumours of the pancreas, Annals of Endocrine Surgery (Indian). 2000, 5: 23-28.
Lo C.Y., Lam K.Y., Wan K.Y., Insular thyroid carcinoma in adolescents, European Journal of Surgery. 2000, 166: 585-588.
Lo C.Y., Optimizing parathyroid autotransplantation during thyroidectomy, Thesis, Master of Surgery, The University of Hong Kong. 2000.
Lo C.Y., Panelist, Clinicopathologic Conference. St. Paul's Doctors' Association, Hong Kong, November 28, 2000, 2000.
Lo C.Y., Reviewer, Asian Journal of Surgery, 2001.
Lo C.Y., Reviewer, Annals of The College of Surgeons of Hong Kong, 2001.
Lo C.Y., Reviewer, British Journal of Surgery, 2001.
Lo C.Y., Lo C.M., Fan S.T., Role of laparoscopic ultrasonography in intraoperative localization of pancreatic insulinoma, Surgical Endoscopy - Ultrasound and Interventional Techniques. 2000, 14: 1131-1135.
Lo C.Y., Lam K.Y., Routine parathyroid autotransplantation during thyroidectomy, Surgery. 2001, 129: S18-S23.
Lo C.Y., Surgical management of thyroid and parathyroid diseases (Invited Lecture), The 33rd Lecture, Hong Kong Pharmacy Techmerem Association, April 9, 2001.
Lo C.Y., Chan F.L., Tam S.C.F., Cheng P.W., Fan S.T., Lam K.S.L., Value of intra-arterial calcium injection with hepatic venous sampling for regionalisation of pancreatic insulinomas., Surgery. 2000, 128: 903-9.
Wat N.M.S., Lo C.Y., Lam Y.K., Chan J.C.W., Lam K.S.L., Germline mutation analysis in Hong Kong Chinese families with multiple endocrine neoplasia type 2., 11th International Congress of Endocrinology, Sydney, Australia. 2000.
Yeung Y., Lo C.Y., Application of genetic testing in management of men I, Departmental Journal Review. 2001.


Researcher : Lui VCH
Project Title:Role of GFRs in the development of enteric nervous system and in the aetiology of Hirschsprung's disease
Investigator(s):Dr. Lui V.C.H. , Prof. Tam P.K.H.
Department:Surgery
Source(s) of Funding:RGC Fundable Projects (Block Grant Funded)
Start Date:February 2000
Completion Date:January 2001
Abstract:
To define the role of GFRs (glial cell-line derived neurotrophic factor family receptors) in the development of enteric nervous system and in the aetiology of Hirschsprung's disease.


Project Title:Defining the role of RET receptor tyrosine kinase in enteric neurogenesis
Investigator(s):Dr. Lui V.C.H. , Dr. Sham M.H., Prof. Tam P.K.H.
Department:Surgery
Source(s) of Funding:Hong Kong Research Grants Council Competitive Earmarked Research Grants
Start Date:September 2000
Abstract:
To create a knock-in dominant negative Ret mutation equivalent of human mutation in green fluorescent embryonic stem (ES) cells and generate mice using the targeted ES cells. The project aims to characterize the molecular mechanism involving RET in lineage commitment and differentiation of enteric NC cells.


Project Title:Study the expression of 3' splicing variants of RET protooncogene in mouse embryogenesis
Investigator(s):Dr. Lui V.C.H. , Dr. Sham M.H., Prof. Tam P.K.H.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:February 2001
Abstract:
To determine the temporal and spatial expression pattern of the 3' alternative spliced transcripts of RET protooncogene in mouse embryogenesis, adhence to provide the basis for a further study to create a new knockout mouse model by targeting a specific isoform of RET.


List of Research Outputs

Chan K.K., Lui V.C.H., Tam P.K.H., Sham M.H., Functional analysis of SOX10 mutations identified in patients with Waardenburg-Hirschprung Syndrome, Develop.Growth Differ. 2001, 43(Suppl.): S97.
Chen Y., Lui V.C.H., Sham M.H., Tam P.K.H., Deficiency of novel inhibitory neurotransmitter carbon monoxide in aganglionic bowel of Hirschsprung's disease., In: The XLVIII Annual International Conference of the British Association of Paediatric Surgeons, London, U.K., 2001.
Cheng W., Lui V.C.H., Chen Q.M., Tam P.K.H., Enteric nervous system, interstitial cells of Cajal, and smooth muscle vacuolization in segmental dilatation of jejunum, Journal of Pediatric Surgery. 2001, 36(6): 930-935.
Fu M., Lui V.C.H., Cheung A.N.Y., Sham M.H., Tam P.K.H., Expression of homeobox gene HoxB5 is localized in the ganglia of human fetal and infant guts but not in Hirschsprung's disease gut, The XLVII Annual International Conference of the British Association of Paediatric Surgenos, London, U.K.. 2001.
Lui V.C.H., Sham M.H., Tam P.K.H., CDX-1 and CDX-2 are expressed in human colonic mucosa and are down-regulated in patients with Hirschsprung's disease associated enterocolitis, Biochim. Biophy. Acta Molecular Basis of Disease. 2001, 1537(2): 89-100.
Lui V.C.H., Li L., Sham M.H., Tam P.K.H., Caudal type homeobox genes CDX-1 and -2: a new clue to the pathogenesis of Hirschsprung's disease associated enterocolitis, 4th European Congress of Paediatric Surgery , Budapest, Hungary, 3-5 May, 2001.
Lui V.C.H., Mulligan L.M., Sham M.H., Tam P.K.H., Role of glial cell-line derived neurotrophic factor family receptors (GFRs) in the pathogenesis of Hirschsprung's disease, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Samy E.T., Sham M.H., Tam P.K.H., Lui V.C.H., Characterization of an alternatively spliced exon at the 3' end of the receptor tyrosine kinase encoding gene RET and its expression in mouse embryonic development, International Congress on Differentiation, Molecular and Cell Biology, Gold Coast, Australia, September 24-28, 2000.
Samy E.T., Sham M.H., Tam P.K.H., Lui V.C.H., Identification of 3' splicing variants of receptor tyrosine kinase encoding gene RET in mouse and expression study of RET splicing variants in developing mouse embryo, Cell Biology International. 2000, 24(12): 968.
Sham M.H., Chen B., Lui V.C.H., Tam P.K.H., Mutations of SOX10 gene in Hirschsprung's disease patients with and without Waardenburg-Shah Syndrome, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Sham M.H., Lui V.C.H., Chen B.L.S., Fu M., Tam P.K.H., Novel mutations of SOX10 suggest a dominant negative role in Waardenburg-Shah syndrome, Journal of Medical Genetics. 2001, 38(9): E30.
Sham M.H., Lui V.C.H., Fu M., Chen B.L.S., Tam P.K.H., SOX10 is abnormally expressed in aganglionic bowel of Hirschsprung's disease infants, Gut. 2001, 49(2): 220-226.


Researcher : Luk JMC
Project Title:Molecular analysis of integrin-mediated leukocyte cell adhesion
Investigator(s):Dr. Luk J.M.C. , Dr. Klickstein L.B., Dr. Wong D.A.
Department:Surgery
Source(s) of Funding:Hong Kong Research Grants Council Competitive Earmarked Research Grants
Start Date:September 1998
Abstract:
To generate a panel of mutant LFA-1 clones that are locked in different activation states; to generate chimeras of human x mouse beta2 integrins and human beta1 x beta2 integrins to study the sites where the antibodies have an effect and the structural interaction betweeen the two subunits; to generate monoclonal antibodies against the LFA-l mutants and the isolated beta2 subunit; to delineate epitope specificity of mAbs recognizing the alpha/beta-pairing sequences, ligand-binding sites, and different conformational states of LFA-l; to isolate and identify movel integrin alpha chain by immunologic and genomic cloning approaches.


Project Title:Differential expression of gap junction communication (GJC) connexin genes during spermatogenesis in rat testes
Investigator(s):Dr. Luk J.M.C. , Dr. Yeung W.S.B.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1999
Abstract:
To investigate the temporal and spatial expression of GJC connexin genes in adult and postnatal (at different stages) rat testes during spermatogenesis.


Project Title:Crystal structure of human leukocyte integrin CD18
Investigator(s):Dr. Luk J.M.C. , Prof. Bjorkman P.J.
Department:Surgery
Source(s) of Funding:Hong Kong Research Grants Council Competitive Earmarked Research Grants
Start Date:January 2000
Abstract:
To study the three-dimensional structure of human leukocyte integrin, a superfamily member of cell adhesion molecules of immune system.


Project Title:Intercellular gap-junction molecules in spermatogenesis and human subfertility
Investigator(s):Dr. Luk J.M.C. , Dr. Tam P.C., Dr. Yeung W.S.B.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:February 2001
Abstract:
To study the expression (mRNA and proteomic) levels of gap-junction connexins and their patterns in human testicular specimens; to detect and characterize mutations of connexin genes leading to human subfertility and related diseases.


List of Research Outputs

Chow V.W.H., Law S.Y.K., Lam K.Y., Luk J.M.C., Wong J., Telomerase activity in small cell esophageal carcinoma, Diseases of the Esophagus. 2001, 14: 139-142.
Lam A.K.Y., Lo C.Y., Wat N.M.S., Luk J.M.C., Lam K.S.L., The clinicopathological features and importance of p53, Rb, and mdm2 expression in phaeochromocytomas and paragangliomas, Journal of Clinical Pathology. 2001, 54(6): 443-448.
Luk J.M.C., A high throughput cell-based assay for screening monoclonal antibodies that modulate LFA-1-ICAM-1 interaction, Antibody Engineering, La Jolla. 2000.
Luk J.M.C., Sadasivan B., Cherry L., Brennar M., Klickstein L.B., Candidate members of an LFA-1 signaling complex on T cells identified by adhesion-activating monoclonal antibodies, Molecular Biology of the Cell. 2000, A4206.
Luk J.M.C., Chan J.K.Y., Tam P.K.H., Differential suppression by tripterygium wilfordii extracts (traditional Chinese medicine) in the allogeneic ratus mixed lymphocyte reaction, Transplantation Proceedings. 2000, 32: 2055-2057.
Luk J.M.C., External Examiner, Ph.D. thesis (2000 - 2001), National University of Singapore. 2001.
Luk J.M.C., Honorary Associate Professor (2000 - 2001), School of Professional and Continuing Education, The University of Hong Kong, 2001.
Luk J.M.C., Tam P.K.H., Fan S.T., Koo M.W.L., Immunosuppressive effects of tripterygium wilfordii polysaccharide on LPS-stimulated human monocytes, Transplantation Proceedings. 2000, 32: 2013-2015.
Luk J.M.C., Visiting Associate Professor of Medicine (2000 - 2001), Harvard University, Brigham and Women's Hospital, Boston, Massachusetts, USA. 2001.
Mok B.W., Luk J.M.C., Mapping of LPS-binding site on human leukocyte integrin beta-2 subunit, Molecular Biology of the Cell. 2000, A4361.
Yang Z., Wu X., Tsui T.Y., Hou Y., Luk J.M.C., Fan S.T., Low-dose FK506 can enhance the effects of recombinant adeno-associated virus mediated hcTLA-4Ig gene transfer, AST/ASTS Transplant 2001 Meeting, A951098. 2001.
Yuen K.Y., Woo P.C.Y., Tai J.W.M., Lie A.K.W., Luk J.M.C., Liang R., Effects of clarithromycin on oral mucositis in bone marrow transplant recipients, Haematologica. 2001, 86: 554-555.


Researcher : Man K
List of Research Outputs

Man K., Fan S.T., Lo C.M., Wong J., Graft injury correlated with portal hemodynamics and intra graft endothelin-1 expression in living donor liver transplantaion in relation to graft size (Abstract), The Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Man K., Fan S.T., Lo C.M., Wong J., Graft injury correlated with portal hemodynamics and intra graft endothelin-1 expression in living donor liver transplantation in relation to graft size (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 369:A926.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L., Fan S.T., Wong J., Liver transplantation in rats using small-for-size grafts - a study of hemodynamic and morphological changes, Archives of Surgery. 2001, 136: 280-285.
Man K., Fan S.T., Pringle manoeuvre during hepatectomy, Asian Journal of Surgery. 2001, 24: 70-77.
Man K., Pringle manoeuvre in hepatectomy, The Drug Information Association (DIA) Meeting, Hong Kong, November 16-19, 2000.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L.F., Fan S.T., Wong J., The mechanism of small-for-size graft injury after liver transplantation, Fourth Shanghai International Symposium on Liver Cancer and Hepatitis and the Second Scientific Meeting of Cheng Si-Yuan (China International) Hepatitis Research Foundation, Pudong, Shanghai, China, September 23-26, 2000.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L.F., Fan S.T., Wong J., The mechanism of small-for-size graft injury after liver transplantation, Journal of Gastroenterology and Hepatology. 2000, 15: 1139 (O-L-7).


Researcher : Ng WM
List of Research Outputs

Choy T.Y., Ng W.M., An update on keloid management, Departmental Journal Review. 2000.
Kwan E., Ng W.M., Hair today, gone tomorrow. Treatment for hair loss, Departmental Journal Review. 2000.
Lam L.K., Hui Y., Ng W.M., Chung H.P., Li K.H., A new method of revision of peri-tracheostomal scar together with closure of tracheo-cutaneous fistula, 7th International Congress of Oriental Aesthetic Plastic Surgery, Seoul, Korea, October 2000.
Yeung E., Ng W.M., Melanoma in the head and neck region: the role of sentinel lymph node biopsy, Departmental Journal Review. 2001.


Researcher : Patil NG
Project Title:A prospective randomized study comparing laparoscopic heriorrhaphy, mesh herniorrhaphy (Lichtenstein's operation) and Bassini's repair
Investigator(s):Dr. Patil N.G. , Dr. Chu K.W., Dr. Ho J.W.C.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1994
Abstract:
To study, in a prospective randomized manner, the new laparoscopic hernia repair using a mesh; to determine whether this new method has any advantage over two traditional hernia repairs, namely, Bassini's repair and mesh herniorrhaphy (Lichtenstein's operation).


Project Title:A prospective randomized controlled trial of minimally invasive repair of incisional hernia
Investigator(s):Dr. Patil N.G. , Dr. Lau H.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:November 2000
Abstract:
To compare the clinical outcomes of conventional open repair and endoscopic repair of incisional hernia using the Gore-tex DualMesh.


List of Research Outputs

Chan Y.W., Lau H., Patil N.G., Lee F.C.W., Para-umbilical hernia: outcome comparison between emergency and elective repairs, Hong Kong Academy of Medicine Second International Congress. Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.
Lau H., Patil N.G., Lee F.C.W., Yuen W.K., A prospective trial of analgesia following endoscopic extraperitoneal inguinal hernioplasty: local wound infiltration versus extraperitoneal instillation of bupivacaine (Abstract), Surgical Endoscopy. 2001, 15 (Suppl.): S142.
Lau H., Patil N.G., Lee F.C.W., Yuen W.K., A prospective trial of analgesia following endoscopic extraperitoneal inguinal hernioplasty: local wound infiltration versus extraperitoneal instillation of bupivacaine, 2001 Annual Meeting, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Missouri, USA, April 18-21, 2001.
Lau H., Chan Y.W., Lee F.C.W., Patil N.G., Clinical factors influencing pain level after ambulatory inguinal herniorrhaphy: a multivariate analysis, Hong Kong Academy of Medicine Second International Congress, Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Early outcomes of laparoscopic totally extraperitoneal hernia repair versus open mesh hernioplasty, Asian Journal of Surgery. 2000, 23: 244-248.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Laparoscopic totally extraperitoneal inguinal hernioplasty: results of 100 consecutive repairs, Annals of Academy of Medicine, Singapore. 2000, 29: 640-643.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Technique for safe placement of re-usable trocars during endoscopic extraperitoneal inguinal hernioplasty, Annals of the College of Surgeons of Hong Kong. 2000, 4: 123-126.
Ng K.C., Lau H., Patil N.G., Lee F.C.W., Epidemiology of hernia in adults, Hong Kong Academy of Medicine Second International Congress, Medical Advances and Information in the New Millennium, Hong Kong, November 2-5, 2000.
Patil N.G., International Editor, Medical Education. U.K., 2001.


Researcher : Poon RTP
Project Title:Prospective evaluation of prognostic significance of tumour angiogenesis and angiogenetic factors in hepatocellular carcinoma
Investigator(s):Dr. Poon R.T.P. , Prof. Fan S.T.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:August 1998
Completion Date:July 2000
Abstract:
To prospectively evaluate the prognostic significance of angiogenesis and expression of angiogenetic factors in hepatocellular carcinoma (HCC) in patients undergoing hepatectomy.


Project Title:Correlation of tumour angiogenic activity and response to transarterial oily chemoembolization in hepatocellular carcinoma
Investigator(s):Dr. Poon R.T.P. , Prof. Fan S.T.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:November 2000
Abstract:
To investigate if quantitation of tumour angiogenic activity and serum angiogenic factor level in patients with hepatocellular carcinoma (HCC) could predict response of the tumour to transarterial chemoembolisation (TACE).


List of Research Outputs

Boen B.K.A., Lee M.K.P., Ng G.W.Y., Shek N.W.M., Yu C.S., Yuen F.F.L., Poon R.T.P., Should active smokers be given a lower priority in the consideration of elective cardiovascular surgery?, Departmental Journal Review. 2000.
Chan C.P., Sy H.P., Sze P.K., Yau K.K., Mau M.M., Poon R.T.P., Should high-risk operations be centralized in high-volume hospitals?, Departmental Journal Review. 2001.
Chan K.C., Cheng H.F., Ho K.C., Koo S.D., Tang M.S.I., Yeung V.K., Poon R.T.P., Telemedicine in surgery, Departmental Journal Review. 2000.
Ho Y.H., Poon R.T.P., Clinical implications of inflammatory mediators in acute pancreatitis, Departmental Journal Review. 2001.
Lee Y.M., Law W.L., Chu K.W., Poon R.T.P., Emergency surgery for obstructing colorectal cancers: a comparison between right-sided and left-sided lesions, Journal of American College of Surgery. 2001, 192: 719-725.
Liu C.L., Fan S.T., Lo C.M., Poon R.T.P., Wong J., Anterior approach for major right hepatic resection for large hepatocellular carcinoma, Annals of Surgery. 2000, 232: 25-31.
Lo S.H., Poon R.T.P., Prevention of pancreaticojejunostomy anastomotic leakage after pancreaticoduodenectomy: an upate review, Departmental Journal Review. 2000.
Poon R.T.P., Fan S.T., Yu W.C., Lam B.K.Y., Chan F.Y.S., Wong J., A prospective longitudinal study of quality of life after resection of hepatocellular carcinoma, Archives of Surgery. 2001, 136: 693-699.
Poon R.T.P., Angiogenesis in hepatocellular carcinoma, Asian Journal of Surgery. 2000, 27: 259-267.
Poon R.T.P., Ng I.O.L., Lau C., Fan S.T., Wong J., Clinical and prognostic significance of microvessel density in hepatocellular carcinoma: a prospective study (Abstract), Proceedings of the Angiogenesis and Cancer: From Basic Mechanisms to Therapeutic Applications, Michigan, U.S.A., 2000.
Poon R.T.P., Ng I.O.L., Lau C., Fan S.T., Wong J., Clinical and prognostic significance of microvessel density in hepatocellular carcinoma: a prospective study, Proceedings of American Association for Cancer Research, Traverse City, USA, October 11-15, 2000.
Poon R.T.P., Fan S.T., Wong J., Clinical implications of circulating angiogenic factors in cancer patients (Review Article), Journal of Clinical Oncology. 2001, 19(4): 1207-1225.
Poon R.T.P., Ng I.O.L., Fan S.T., Lai E.C.S., Lo C.M., Liu C.L., Wong J., Clinicopathologic features of long-term survivors and disease-free survivors after resection of hepatocellular carcinoma: a study of a prospective cohort, Journal of Clinical Oncology. 2001, 19(12): 3037-3044.
Poon R.T.P., Fan S.T., Ng I.O.L., Lo C.M., Liu C.L., Wong J., Different risk factors and prognosis of early and late intrahepatic recurrence after resection of hepatocellular carcinoma, Cancer. 2000, 89: 500-507.
Poon R.T.P., Poon J.T.C., Duodenal arteriovenous malformation: a rare cause of massive gastrointestinal bleeding, Gastrointestinal Endoscopy. 2000, 52: 101-104.
Poon R.T.P., Fan S.T., Hepatocellular carcinoma, In: Yuri A.P. (ed.), Hepatic Surgery (Cirugia Hepatica) (Chile). 2000, 131-140.
Poon R.T.P., Fan S.T., Interval laparoscopic cholecystectomy in the management of acute biliary pancreatitis (Invited Commentary), HBP Surgery. 2000, 11: 322-323.
Poon R.T.P., Fan S.T., Liver disease and parental nutrition, In: Rombeau J.L. and Rolandelli R. H. (eds.), Clinical Nutrition, Parenteral Nutrition. Philadelphia, USA, W.B. Saunders, 2001, 3rd edition: 392-406.
Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Ng I.O.L., Wong J., Long-term prognosis after resection of hepatocellular carcinoma associated with hepatitis B-related cirrhosis, Journal of Clinical Oncology. 2000, 18: 1094-1101.
Poon R.T.P., Liu C.L., Lo C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy (Abstract), Digestive Disease Week 2000, San Diego, U.S.A. 2000.
Poon R.T.P., Liu C.L., Lo C.M., Lam C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy, Archives of Surgery. 2001, 136: 11-16.
Poon R.T.P., Fan S.T., Opinions and commentary on treating pancreatic cancer, Surgical Clinics of North America. 2001, 81: 625-636.
Poon R.T.P., Fan S.T., Wong J., Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma, Annals of Surgery. 2000, 232: 10-24.
Poon R.T.P., Ng I.O.L., Lau C., Zhu L.X., Yu W.C., Lo C.M., Fan S.T., Wong J., Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: a prospective study, Annals of Surgery. 2001, 233: 227-235.
Tsang H.F., Poon R.T.P., Local ablative treatment of hepatocellular carcinoma, Departmental Journal Review. 2000.
Yiu C.P., Poon R.T.P., Current management of acute necrotizing pancreatitis (ANP), Departmental Journal Review. 2001.


Researcher : Ren Y
List of Research Outputs

Ren Y., Wu A.Y.Y., Chan W.K., Lau W.C.S., Increased apoptotic blood neutrophils and macrophages and decreased clearance of apoptotic neutrophils in systemic lupus erythematosus, Hong Kong Practitioner. The Hong Kong Practitioner, 2001, 23(2) supple: 31.
Ren Y., Stuart L., Lindberg F.P., Rosenkranz A.R., Chen Y., Mayadas T.N., Savill J., Nonphlogistic clearance of late apoptotic neutrophils by macrophages: efficient phagocytosis independent of b2 intergrins, Journal of Immunology. 2001, 166: 4743-4750.
Ren Y., Lan H.Y., Wu A.Y.Y., Yeung J.S.L., Lau W.C.S., Osteopontin in rheumatoid arthritis and osteoarthritis, Hong Kong Practitioner. The Hong Kong Practitioner, 2001, 23(2) Supple: 32.


Researcher : Saing H
Project Title:An assessment of gastro-oesophageal reflux in children by extended pH monitoring of the distal oesophagus
Investigator(s):Prof. Saing H. , Dr. Mya H.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:December 1987
Abstract:
An assessment of gastro-oesophageal reflux (GOR) in: a) children whose primary pathology is known to be associated with GOR, e.g. oesophageal atresia, pyloric stenosis, etc.; b) children whose clinical features are suggestive of GOR; c) asymptomatic control to have a base line for Chinese children.


Project Title:An assessment of gastro-oesophageal reflux in children by extended pH monitoring of the distal oesophagus
Investigator(s):Prof. Saing H. , Dr. Mya H.
Department:Surgery
Source(s) of Funding:Lee Wing Tat Medical Research Fund
Start Date:December 1987
Abstract:
An assessment of gastro-oesophageal reflux (GOR) in: a) children whose primary pathology is known to be associated with GOR, e.g. oesophageal atresia, pyloric stenosis, etc.; b) children whose clinical features are suggestive of GOR; c) asymptomatic control to have a base line for Chinese children.


Project Title:An assessment of gastro-oesophageal reflux in children by extended pH monitoring of the distal oesophagus
Investigator(s):Prof. Saing H. , Dr. Mya H.
Department:Surgery
Source(s) of Funding:Madam Fung Wong Fung Ting and Esther F.Y. Fung Fund for Clinical Research
Start Date:December 1987
Abstract:
An assessment of gastro-oesophageal reflux (GOR) in: a) children whose primary pathology is known to be associated with GOR, e.g. oesophageal atresia, pyloric stenosis, etc.; b) children whose clinical features are suggestive of GOR; c) asymptomatic control to have a base line for Chinese children.


Project Title:Augmentation of small intestine by tissue expander in rabbits
Investigator(s):Prof. Saing H.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1993
Abstract:
To determine the effect of augmentation by tissue expander in small intestine. The aim is to increase the mucosal surface area of the small intestine thereby increasing the absorptive capacity.


List of Research Outputs

Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Liver transplantation is not contraindicated in infancy, Transplantation Proceedings. 2000, 32(7): 2142-2143.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Post liver transplantation stenosis of biliary-enteric anastomoses in infancy: diagnosis and treatment, Transplantation Proceedings. 2000, 32(7): 2233-2234.
Cheng W., Saing H., Zhou H., Han Y., Peh W., Tam P.K.H., Ultrasound assessment of scald scars in Asian children receiving pressure garment therapy, Journal of Pediatric Surgery. 2001, 36(3): 466-469.
Khong P.L., Peh W.C.G., Lam C.H.L., Chan K.L., Cheng W., Lam W.W.M., Saing H., Tam P.K.H., Leong Fung L.L.Y., Low L.C.K., Ultrasound-guided hydrostatic reduction of childhood intussusception: technique and demonstration, RadioGraphics. 2000, 20(5): E1.
Khong P.L., Peh W.C., Lam C.H., Chan K.L., Cheng W., Lam W.W., Ai V.H., Saing H., Tam P.K., Leong L.L., Low L.C.K., Ultrasound-guided hydrostatic reduction of childhood intussusception: technique and demonstration, Radiographics. 2000, 20(5): E1-e1.
Lam W.W.M., Chan F.L., Saing H., Direct sagittal CT of oesophageal atresia correlates well with operative findings, Asian Oceanian Journal of Radiology. 2000, 5(2): 81-85.
Lam W.W.M., Chan F.K., Saing H., Sagittal CT of imperforate anus: imaging-surgical correlation, Asian Oceanian Journal of Radiology. 2001, 6(1): 41-43.
Saing H., Aung K.Y.I., Maung M., Ablation of posterior urethral valves in the newborn using Fogarty catheter: a simple and inexpensive method for developing countries, 34th Annual Meeting of the Pacific Association of Pediatric Surgeons, Kyoto, Japan, April 4, 2001.
Saing H., Associate Editor, Asian Journal of Surgery. 2001.
Saing H., Board of Directors (1994 - present), Asian Association of Pediatric Surgeons. 2001.
Saing H., Chair of Session, Pediatric Surgery, 6th Congress of the Cambodian Surgical Society, Cambodia, October 25-26, 2000.
Saing H., Chair: Plenary Lecture 4, Minimally invasive surgery in children: the past, the present, the future, 17th Congress of Asian Association of Pediatric Surgeons, Fukuoka, Japan, November 6-9, 2000.
Saing H., Chairman, Pitfall of surgical technique of living donor liver transplantaton in adult recipients, Prograf Okinawa Summit, Okinawa, Japan, February 25, 2001. 2001.
Saing H., Chairman, Publication Committee (1997 - present), Asian Association of Paediatric Surgeons. 2001.
Saing H., Examiner in Surgery, Licentiate Committee, Medical Council of Hong Kong. 2001.
Saing H., Honorary Consultant Surgeon (1979 - present), The Department of Health, HKSAR Government and the Hospital Authority, Queen Mary Hospital, Hong Kong. 2001.
Saing H., Honorary Professor of Paediatric Surgery (1995 - present), Ministry of Health, Government of the Union of Myanmar, Myanmar. 2001.
Saing H., International Advisor (2000 - present), 3rd World Congress on Pediatric Esophagus, New Delhi, India, February 1-3, 2002. 2001.
Saing H., Medical education in the new millennium, Workshop of Medical Education, Institute of Medicine 1, Department of Medical Sciences, Ministry of Health, Yangon, Myanmar, January 25, 2001.
Saing H., Member of Editorial Board, Journal of Pediatric Surgery. 2001.
Saing H., Member, Executive Committee, The Society for the Relief of Disabled Children. 2001.
Saing H., Member, Guest Assistance Program, Pacific Association of Pediatric Surgeons. 2001.
Saing H., Member, Hospital Governing Committee, Duchess of Kent Children's Hospital. 2001.
Saing H., Member, Nominations Committee, Pacific Association of Pediatric Surgeons. 2001.
Saing H., Paediatric liver transplantation, 13th Surgeons Conference, Myanmar Medical Association, Yangon, Myanmar, November 18-22, 2000.
Saing H., Fan S.T., Wei W.I., Chan K.L., Lo C.M., Mya G.H., Tsoi N.S., Yuen K.Y., Ng I.L.O., Chau M.T., Tso W.K., Chan J.F.K., Wong J., Pediatric liver transplantation: the Hong Kong experience, 6th Congress of the Cambodian Surgical Society, Cambodia, October 25-26, 2000.
Saing H., Pediatric surgery training and delivery in Asia, 17th Congress of Asian Association of Pediatric Surgeons, Fukuoka, Japan, November 6-9, 2000.
Saing H., Fan S.T., Chan K.L., Wei W.I., Lo C.M., Mya G.H., Wong J., Portoenterostomy complimented by liver transplantation for biliary atresia: the Queen Mary Hospital, Hong Kong experience, 6th Congress of the Cambodian Surgical Society, October 25-26, 2000.
Saing H., Radical excision is the treatment of choice for choledochal cyst, 6th Congress of the Cambodian Surgical Society, Cambodia, October 25-26, 2000.
Saing H., Reviewer, Journal of Fetal Diagnosis and Therapy. 2001.
Saing H., Today's teaching for tomorrow's doctors (Invited Lecture), 13th Surgeons Conference, Myanmar Medical Association, Wangon, Myanmar, November 18-22, 2000.
Saing H., Today's teaching for tomorrow's doctors (Invited Lecture), 47th Myanmar Medical Conference, Myanmar Medical Association, Mandalay, Myanmar, January 19-23, 2001.
Saing H., Training and delivery of pediatric surgery services in Asia, Journal of Pediatric Surgery. 2000, 35(11): 1606-1611.
Van Heurn L.W.E., Cheng W., De Vries B., Saing H., Kootstra G., Tam P.K.H., Associated anomalies in oesophageal atresia in Asians and Europeans, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.


Researcher : Samy ET
List of Research Outputs

Samy E.T., Sham M.H., Tam P.K.H., Lui V.C.H., Identification of 3' splicing variants of receptor tyrosine kinase encoding gene RET in mouse and expression study of RET splicing variants in developing mouse embryo, Cell Biology International. 2000, 24(12): 968.


Researcher : Sun N
List of Research Outputs

Sun N., Chan K.L., OK-432 (Picibanil) therapy for lymphangioma: collective experience in the literature, Annals of the College of Suregons of Hong Kong. 2001, 5: 55-58.
Sun N., Cheung T.T., Kwong P.L., Chan K.L., Tam P.K.H., Varicocele: laparoscopic clipping and colour doppler ultrasound follow-up, 34th Annual Meeting of Pacific Association of Pediatric Surgeons , Kyoto, Japan, April 4-8, 2001.


Researcher : Tam PC
List of Research Outputs

Au W.Y., Tam P.C., Ma E.S.K., Lam A.K.Y., Giant myelolipoma in a patient with thalassemia intermedia, American Journal of Hematology. 2000, 65: 265-266.
Cheung M.C., Leung S.Y.L., Wong B.B.W., Lee F.C.W., Tam P.C., Can ultrasonography (USG) plus plain radiograph replace intravenous urogram (IVU) in prediction of residual ureteric obstruction after primary in-situ extracorporeal shockwave lithotripsy (ESWL) for ureteric stone - a prospective study, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Cheung M.C., Lo S.H., Khoo U.S., Tam P.C., Collecting duct carcinoma presenting as a bleeding complicated renal cyst, Annals of the College of Surgeons of Hong Kong. 2000, 4: 167-168.
Cheung M.C., Lee F.C.W., Yip S.K.H., Tam P.C., Outpatient holmium laser lithotripsy using semirigid ureteroscope, European Urology. 2001, 39: 702-708.
Cheung M.C., Yip S.K.H., Lee F.C.W., Tam P.C., Outpatient ureteroscopic lithotripsy: selective internal stenting and factors enhancing success, Journal of Endourology. 2000, 14: 559-564.
Ho K.L., Leung S.Y.L., Cheung M.C., Wong B.B.W., Chu S.S.M., Lee F.C.W., Tam P.C., An audit of urological day surgery service - a 5-year experience in the Day Surgery Centre in Tung Wah Hospital, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Lam M.F., Li F.K., Choy C.B.Y., Tang S.C.W., Lo W.K., Lui S.L., Chu S.M., Tam P.C., Chan D.T.M., Lai K.N., The impact of the establishment of a multiorgan transplantation program on cold ischemia time and delayed graft function in renal transplantation, Transplantation Proceedings. 2000, 32(7): 1611-1612.
Leung S.Y.L., Cheung M.C., Wong B.B.W., Chu S.S.M., Lee F.C.W., Tam P.C., Same day transurethral resection - vaporization of the prostate (TURVP) for the treatment of benign prostatic hyperplasia, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Tse J.Y.M., Yeung W.S.B., Lau E.Y.L., Ng E.H.Y., Tam P.C., So W.W.K., Tang M.H.Y., Lau E.T., Ho P.C., Transmission of the Y chromosome microdeletion to a baby boy conceived after intracytoplasmic sperm injection (Case Report), Chinese Medical Journal. 2001, 114(1): 97-99.
Wong B.B.W., Cheung M.C., Leung S.Y.L., Ho K.L., Chu S.S.M., Lee F.C.W., Tam P.C., The value of noncontrast helical computer tomography in the diagnosis of acute ureteric colic, 6th Annual Scientific Meeting, Hong Kong Urological Association, Hong Kong, November 12, 2000.
Xi S., Tam P.C., Brown G.M., Pang S.F., Shiu S.Y.W., Potential involvement of mt1 receptor and attenuated sex steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells, Journal of Pineal Research. 2000, 29: 172-183.
Yeung Y., Cheung M.C., Chan G.S.W., Cheung A.N.Y., Tam P.C., Primary actinomycosis mimicking urachal carcinoma, Urology. 2001, 58(3): 462.
Yip K.H., Cheung M.C., Wong B.B.W., Lee F.C.W., Tam P.C., Outpatient ureteroscopic lithotripsy: selective internal stenting and factors enhancing success, 25th Congress of the Societe and Internationale d'Urologie, Singapore, October 29 - November 2, 2000.


Researcher : Tam PKH
Project Title:New methods of immunosuppression in allogenic small bowel transplantation
Investigator(s):Prof. Tam P.K.H.
Department:Surgery
Source(s) of Funding:Fujisawa
Start Date:July 1996
Completion Date:June 2001
Abstract:
To confirm our findings in an orthotopic rat model and a pig model leading to clinical applications. New immunosuppression to induce indefinit graft survival by (1) targeting the delayed immune response following FK506 pretreatment and, (2) introducing new agents to block CD28 pathway will be studied. New methods of monitoring early rejection by cytokine measurements will be evaluated.


Project Title:Transgenesis animals as bioreactors: production of a new immunosuppressive protein CTLA4Ig by transgenesis
Investigator(s):Prof. Tam P.K.H. , Prof. Cheah K.S.E., Prof. Dallman M.J., Prof. Sun F.Z., Dr. Wong N.S.
Department:Surgery
Source(s) of Funding:Vice-Chancellor's Development Fund
Start Date:July 1997
Abstract:
The use of transgenic farm animals as bioreactors is a potentially powerful and important new industry for the next century. This application of transgenic technology, in combination with the recent advance in ability to clone animals from adult cells, enhances the potential of transgenic animal bioreactors as major producers of therapeutic proteins. Therefore by initiating research in this area there are immediate and long-term benefits to Hong Kong and China.


Project Title:The role of neurotrophic factors in Hirschsprung's disease and idiopathic slow transit constipation - a common link?
Investigator(s):Prof. Tam P.K.H. , Dr. Anand P., Prof. Williams N.S.
Department:Surgery
Source(s) of Funding:UK/HK Joint Research Scheme (British Council / Hong Kong Research Grants Council)
Start Date:January 1998
Abstract:
To clarify further the role of neurotrophic factors and their receptors in Hirschsprung's disease (HD) by elucidating the genotype-phenotype correlation; to undertake a comparative study of the involvement of these trophic factors in Hirschsprung's disease and idiopathic slow transit constipation (STC) and test the hypothesis that there is a common aetiological link between these two conditions.


Project Title:Immune mechanisms and new immunosuppressive approaches in small bowel transplantation
Investigator(s):Prof. Tam P.K.H. , Prof. Dallman M.J.
Department:Surgery
Source(s) of Funding:Hong Kong Research Grants Council Competitive Earmarked Research Grants
Start Date:September 1998
Completion Date:August 2000
Abstract:
To advance our understanding of the unique immune mechanisms responsible for the severe rejection in small bowel transplantation and to develope new, effective and selectively targeted immunosuppressive approaches which will, at least, allow long-term graft survival and, ideally, also induce tolerance.


Project Title:Establishing a "train-the-trainers" programme for paediatric surgery in China
Investigator(s):Prof. Tam P.K.H. , Dr. Lin C.L.
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation Grant
Start Date:October 1998
Abstract:
To improve the standard of surgical care of children in China through the establishment of a scheme of "train-the-trainers"; to improve our understanding of special paediatric surgical issues relevant to the Chinese population (e.g. disease patterns, transferability of western "advances" to China etc.) through systematic exchanges with major centres in China and hence enhance our ability to deliver better surgical care to children in Hong Kong.


Project Title:Molecular mechanisms of intestinal ischaemia-reperfusion injury
Investigator(s):Prof. Tam P.K.H. , Dr. Chan K.L., Prof. Fung P.C.W., Dr. Luk J.M.C., Dr. Siow Y.L.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1999
Abstract:
To determine the pathogenetic role of free radicals, cytokines, adhesion moleculars and stress activated protein kinases in intestine I/R; to investigate if apoptosis represents the final common pathway for these molecular signals of intestine I/R; to test the efficacy of the novel approach of "ischaemic preconditioning" in ameliorating intestinal I/R injury, and if the findings are positive, to elucidate the molecular mechanisms involved.


Project Title:Analysis of single nucleotide polymorphism (SNPs) of the RET protooncogene in RET associated diseases
Investigator(s):Prof. Tam P.K.H. , Dr. Corvi R., Dr. Lui V.C.H., Prof. Romeo G.
Department:Surgery
Source(s) of Funding:France/Hong Kong Joint Research Scheme
Start Date:January 2000
Abstract:
To examine the significance of somatic mutations of RET gene in the pathogenesis of HSCR and to test the double- or multiple-hit hypothesis that somatic mutations of RET gene may contribute to the majority of sporadic cases of HSCR; to determine the contribution of somatic RET mutations to thyroid tumours by comparative analysis of materials from French, Italian and Hong Kong cohorts.


Project Title:High throughput analysis of expression profile of genes implicated in enteric neural development and in Hirschsprung's Disease in human
Investigator(s):Prof. Tam P.K.H. , Dr. Lui V.C.H., Dr. Sham M.H.
Department:Surgery
Source(s) of Funding:RGC Fundable Projects (Block Grant Funded)
Start Date:February 2000
Completion Date:January 2001
Abstract:
The enteric nervous system (ENS) is a highly organized colleciton of neruons within the gastrointestinal tract. The ENS controls motility and other important functions ofthe gut and act autonomously. The ENS arises from vagal neural crest cells that d evelop through a complex process of migration, proliferation, growth and differentiation.


Project Title:Multiple molecular approaches for elucidating the multigenic nature of hirschsprung's disease in Chinese patients
Investigator(s):Prof. Tam P.K.H. , Dr. Lui V.C.H., Prof. Romeo G., Dr. Sham M.H.
Department:Surgery
Source(s) of Funding:Hong Kong Research Grants Council Competitive Earmarked Research Grants
Start Date:September 2000
Abstract:
The enteric nervous system (ENS) controls gut mobility. Abnormal ENS development leads to a major intestinal anomaly Hirschsprung's disease (HSCR) or congenital intestinal aganglionosis which manifests as functional intestinal obstruction. The present study aims to understand the role of somatic mutations and neutral sequence variant of RET gene in the pathogenesis of HSCR.


Project Title:Investigation of the role of Sox10 gene in enteric nervous system development by explant and organ culture systems
Investigator(s):Prof. Tam P.K.H. , Dr. Lui V.C.H., Dr. Sham M.H.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:May 2001
Abstract:
To investigate the specific functions for Sox10 in enteric glia differentiation; to study the effect of the gut microenvironment on the differentiation of neural crest cells using normal mouse strain and a Sox10 mutant mouse strain Dom.


List of Research Outputs

Chan G.C.F., Ha S.Y., Lau Y.L., Chan K.L., Tam P.K.H., Cheung A.N.Y., Letter to the Editor: Linitis plastica presenting as malignant ascites, Medical and Pediatric Oncology. 2001, 34: 1-2.
Chan G.C.F., Chan K.L., Kwong D.L.W., Chiang A.K.S., Lee T.L., Ha S.Y., Tam P.K.H., Lau Y.L., Malignant tumours in the head and neck region in childhood: good outcome with current therapeutic approach, 7th Hong Kong International Cancer Congress, Hong Kong, 7-9 December 2000.
Chan K.K., Lui V.C.H., Tam P.K.H., Sham M.H., Functional analysis of SOX10 mutations identified in patients with Waardenburg-Hirschprung Syndrome, Develop.Growth Differ. 2001, 43(Suppl.): S97.
Chan K.L., Zhou H., Ng D.K.K., Tam P.K.H., A prospective study of a one-week non- bismuth quadruple therapy for childhood Helicobacter pylori infection, Journal of Pediatric Surgery. 2001, 36: 1008-1011.
Chan K.L., Hui C., Wo J.Y.H., Tipoe G.L., Fung P.C.W., Tam P.K.H., Developmental profile of manganese and copper zinc superoxide dismutases in rat intestines and its implications in ischaemia and reperfusion injury, 34th Annual Meeting of Pacific Assoication of Pediatric Surgeons, Kyoto, Japan, April 4-8, 2001.
Chan K.L., Guo W.H., Chan K.W., Tam P.K.H., FR167653 ameliorates intestinal allograft ischemia injury, Transplantation Proceedings. 2000, 32: 1643-1644.
Chan K.L., Tang M.H.Y., Sin S.Y., Wong H.S., Tang R., Tam P.K.H., In utero pleuro-amniotic shunting for bilateral fetal chylothorax and hydrop fetalis, XVII Congress of Asian Association of Pediatric Surgeons. Fukuoka, Japan, November 6-9, 2000.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Liver transplantation is not contraindicated in infancy, Transplantation Proceedings. 2000, 32(7): 2142-2143.
Chan K.L., Tam P.K.H., Meconium ileus-like conditions in Hong Kong Chinese neonates, XVII Congress of Asian Association of Pediatric Surgeons, Fukuoka, Japan, November 6-9, 2000.
Chan K.L., Hui C., Wo J.Y.H., Tipoe G.L., Fung P.C.W., Tam P.K.H., Revisiting ischaemia and reperfusion injury as a possible cause for necrotising enterocolitis, 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, April 4-8, 2001.
Chan K.L., Guo W.H., Tam P.K.H., Technical refinements for successful small bowel transplantation in pig, Transplantation Proceedings. 2000, 32: 2488-2489.
Chan K.L., Zhou H., Tam P.K.H., Helicobacter pylori negative childhood duodenal ulcers: a prospective study, XVII Congress of Asian Association of Pediatric Surgeons, Fukuoka, Japan, November 6-9, 2000.
Chen Y., Lui V.C.H., Sham M.H., Tam P.K.H., Deficiency of novel inhibitory neurotransmitter carbon monoxide in aganglionic bowel of Hirschsprung's disease., In: The XLVIII Annual International Conference of the British Association of Paediatric Surgeons, London, U.K., 2001.
Chen Y.S., Yau T.O., Tam P.K.H., Sham M.H., Characterization of an enhancer element for establishing transgenic mouse models for enteric nervous system development, The 18th International Congress of Biochemistry and Molecular Biology, Birmingham, UK. 2000.
Cheng W., Tam P.K.H., Apoptosis in murine duodenum during embryonic development, Pediatric Surgery International. 2000, 16: 485-487.
Cheng W., Lui V.C.H., Chen Q.M., Tam P.K.H., Enteric nervous system, interstitial cells of Cajal, and smooth muscle vacuolization in segmental dilatation of jejunum, Journal of Pediatric Surgery. 2001, 36(6): 930-935.
Cheng W., Tam P.K.H., Gastric electrical activity normalises in the first decade of life, European Journal of Pediatric Surgery. 2000, 10: 295-299.
Cheng W., Knowles C.H., Anand P., Tam P.K.H., Hirschsprung's disease: a generalised neuropathy, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Cheng W., Au D.K.K., Knowles C.H., Tam P.K.H., Anand P., Hirschsprung's disease: a more generalised neuropathy?, Journal of Pediatric Surgery. 2001, 36 (2): 296-300.
Cheng W., Zhou H., Chan K.L., Tam P.K.H., Management of acute appendicitis: specialist-based versus trainee-based service, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Cheng W., Lee P.K.H., Ho W.K.W., Tam P.K.H., Pediatric pedestrian injuries in densely populated city, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Cheng W., Saing H., Zhou H., Han Y., Peh W., Tam P.K.H., Ultrasound assessment of scald scars in Asian children receiving pressure garment therapy, Journal of Pediatric Surgery. 2001, 36(3): 466-469.
Facer P., Knowles C.H., Thomas P.K., Tam P.K.H., Williams N.S., Anand P., Decreased tyrosine kinase C expression may reflect developmental abnormalities in Hirschsprung's disease and idiopathic slow-transit constipation, British Journal of Surgery. 2001, 88: 545-552.
Facer P., Dyer N., Ford A.P., Knowles C., Tam P.K.H., Anand P., Novel capsaicin (VR1) and purinergic (P2X3) receptors in Hirschsprung's intestine, 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto , Japan, April 4-8, 2001.
Fu M., Lui V.C.H., Cheung A.N.Y., Sham M.H., Tam P.K.H., Expression of homeobox gene HoxB5 is localized in the ganglia of human fetal and infant guts but not in Hirschsprung's disease gut, The XLVII Annual International Conference of the British Association of Paediatric Surgenos, London, U.K.. 2001.
Guo W.H., Tian L., Dallmam M., Tam P.K.H., Heterotoic versus orthotopic small bowel transplantation: survival and immunological differences, 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, April 4-8, 2001.
Guo W.H., Chan K.L., Fung P.C.W., Chan K.W., Tam P.K.H., Nitric oxide protects segmental intestinal grafts from ischaemia and reperfusion I/R injury, Transplantation Proceedings. 2000, 32: 1297-1298.
Guo W.H., Tian L., Yuen Z.W., Chan K.L., Wo J.Y.H., Nicholls G., Dallman M., Tam P.K.H., Recipient FK506 pretreatment regimens in rat small bowel transplantation: allograft survival, function, and systemic infection, Journal of Pediatric Surgery. 2000, 35: 1600-1605.
Guo W.H., Tian L., Chan K.L., Dallman M., Tam P.K.H., Role of CD4+ and CD8+ T cells in early and late acute rejection of small bowel allograft, Journal of Pediatric Surgery. 2001, 36(2): 352-356.
Guo W.H., Tian L., Chan K.L., Tam P.K.H., Role of activated helper and cytotoxic T cells in early and late rejection of small bowel allograft, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Guo W.H., Tian L., Tam P.K.H., The production of a novel immunosuppressive fusion protein CTLA4-Ig and a study of its immunosuppressive function, 7th Hong Kong International Cancer Congress. 5th Research Postgraduate Symposium, Hong Kong, December 7-9, 2000.
Khong P.L., Chan G.C.F., Shek T.W.H., Tam P.K.H., Chan F.L., PNET (peripheral neuroectodermal tumour) everywhere: a pictorial review., Radiology 2000 Hong Kong International Congress and 8th Annual Scientific Meeting. Hong Kong College of Radiologists. August, 2000. Hong Kong.
Khong P.L., Peh W.C.G., Lam C.H.L., Chan K.L., Cheng W., Lam W.W.M., Saing H., Tam P.K.H., Leong Fung L.L.Y., Low L.C.K., Ultrasound-guided hydrostatic reduction of childhood intussusception: technique and demonstration, RadioGraphics. 2000, 20(5): E1.
Khong P.L., Chan G.C.F., Shek T.W.H., Tam P.K.H., Chan F.L., Unusual locations of peripheral primitive neuroectodermal tumors (PNET) in children: imaging features and clinico-pathological correlation, Inaugural Meeting of the Asian and Oceanian Society for Pediatric Radiology (AOSPR) 2000. France.
Lam W.W.M., Tam P.K.H., Chan F.L., Chan K.L., Cheng W., Esophageal atresia and tracheal stenosis: use of three-dimensional CT and virtual bronchoscopy in neonates, infants and children, American Journal of Roentgenology. 2000, 174: 1009-1012.
Lam W.W.M., Tam P.K.H., Ai V.H.G., Chan K.L., Chan F.L., Leong L., Using gadolinium-infusion MR venography to show the impalable testis in pediatric patients, American Journal of Roentgenology. 2001, 176: 1221-1226.
Lui V.C.H., Sham M.H., Tam P.K.H., CDX-1 and CDX-2 are expressed in human colonic mucosa and are down-regulated in patients with Hirschsprung's disease associated enterocolitis, Biochim. Biophy. Acta Molecular Basis of Disease. 2001, 1537(2): 89-100.
Lui V.C.H., Li L., Sham M.H., Tam P.K.H., Caudal type homeobox genes CDX-1 and -2: a new clue to the pathogenesis of Hirschsprung's disease associated enterocolitis, 4th European Congress of Paediatric Surgery , Budapest, Hungary, 3-5 May, 2001.
Lui V.C.H., Mulligan L.M., Sham M.H., Tam P.K.H., Role of glial cell-line derived neurotrophic factor family receptors (GFRs) in the pathogenesis of Hirschsprung's disease, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Luk J.M.C., Chan J.K.Y., Tam P.K.H., Differential suppression by tripterygium wilfordii extracts (traditional Chinese medicine) in the allogeneic ratus mixed lymphocyte reaction, Transplantation Proceedings. 2000, 32: 2055-2057.
Luk J.M.C., Tam P.K.H., Fan S.T., Koo M.W.L., Immunosuppressive effects of tripterygium wilfordii polysaccharide on LPS-stimulated human monocytes, Transplantation Proceedings. 2000, 32: 2013-2015.
Martucciello G., Tam P.K.H., RET protein in human fetal development and in Hirschsprung's disease, In: Holschneider A.M. and Puri P. (eds.), Hirschsprung's Disease and Allied Disorders, 2nd edition. U.K., Harwood Academic Publishers, 2000, Chapter 6: 81-88.
Samy E.T., Sham M.H., Tam P.K.H., Lui V.C.H., Characterization of an alternatively spliced exon at the 3' end of the receptor tyrosine kinase encoding gene RET and its expression in mouse embryonic development, International Congress on Differentiation, Molecular and Cell Biology, Gold Coast, Australia, September 24-28, 2000.
Samy E.T., Sham M.H., Tam P.K.H., Lui V.C.H., Identification of 3' splicing variants of receptor tyrosine kinase encoding gene RET in mouse and expression study of RET splicing variants in developing mouse embryo, Cell Biology International. 2000, 24(12): 968.
Sancandi T., Ceccherini I., Costa M., Fava M., Chen B., Wu Y., Hofstra R., Laurie T., Griffths M., Burge D., Tam P.K.H., Incidence of RET mutations in patients with Hirschsprung's disease, Journal of Pediatric Surgery. 2000, 35: 139-143.
Sham M.H., Chen B., Lui V.C.H., Tam P.K.H., Mutations of SOX10 gene in Hirschsprung's disease patients with and without Waardenburg-Shah Syndrome, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Sham M.H., Lui V.C.H., Chen B.L.S., Fu M., Tam P.K.H., Novel mutations of SOX10 suggest a dominant negative role in Waardenburg-Shah syndrome, Journal of Medical Genetics. 2001, 38(9): E30.
Sham M.H., Lui V.C.H., Fu M., Chen B.L.S., Tam P.K.H., SOX10 is abnormally expressed in aganglionic bowel of Hirschsprung's disease infants, Gut. 2001, 49(2): 220-226.
Siow Y.L., Chan K.L., Tam P.K.H., Stress-activated protein (SAP) kinase: a new marker for intestinal ischemia, Transplantation Proceedings. 2000, 32: 1302-1303.
Sun N., Cheung T.T., Kwong P.L., Chan K.L., Tam P.K.H., Varicocele: laparoscopic clipping and colour doppler ultrasound follow-up, 34th Annual Meeting of Pacific Association of Pediatric Surgeons , Kyoto, Japan, April 4-8, 2001.
Tam P.K.H., Advisor/Reviewer (1999 - present), Quality Education Fund Projects, 2001.
Tam P.K.H., Chief, Division of Paediatric Surgery (1996 - present), Department of Surgery, Queen Mary Hospital, 2001.
Tam P.K.H., Council Member (2000 - present), The College of Surgeons of Hong Kong, 2001.
Tam P.K.H., Editor (1999 - present), Annals of the College of Surgeons of Hong Kong, 2001.
Tam P.K.H., Endoscopy in infants and children, Inaugural Seminar, The Hong Kong Society of Paediatric Gastroenterology, Hepatology and Nutrition, Hong Kong. October 28, 2000.
Tam P.K.H., Examiner (1995 - present), Intercollegiate Specialty Board in Paediatric Surgery, U.K., 2001.
Tam P.K.H., Examiner in Fellowship, General Surgery (1990 - present), Royal College of Surgeons, Edinburgh, 2001.
Tam P.K.H., Examiner, Diploma in Child Health (1995 - present), Royal College of Physicians, U.K., 2001.
Tam P.K.H., Foundation Vice-President (1999 - present), Hong Kong Society of Paediatric Gastroenterology, Hepatology and Nutrition, 2001.
Tam P.K.H., General overview (Invited Lecutre), Symposium on Circumcision of the College of Surgeons of Hong Kong, Hong Kong, June 18, 2001.
Tam P.K.H., Honorary Consultant (1998 - present), Queen Mary Hospital, 2001.
Tam P.K.H., Honorary Consultant (1999 - present), Kwong Wah Hospital, 2001.
Tam P.K.H., International Advisor (1997 - present), Annals of the Faculty of Medicine, Federal University of Pernambuco, Brazil, 2001.
Tam P.K.H., Chan K.L., Laparoscopic anorectal pullthrough for high imperforate anus-technical variations., 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, 4-8 April, 2001.
Tam P.K.H., Laparoscopic surgery for paediatric gastrointestinal diseases (Invited Lecture), Scientific Meeting of Hong Kong Society of Paediatric Gastroenterology, Hepatology and Nutrition, Hong Kong, May 17, 2001.
Tam P.K.H., Laparoscopic surgery in children, Archives of Disease in Childhood. 2000, 82: 240-243.
Tam P.K.H., Member of Editorial Board (1997 - present), Pediatric Surgery International, 2001.
Tam P.K.H., Member, Biology and Medicine Panel (2000 - present), Research Grants Council, In: , 2001.
Tam P.K.H., Member, Board of Paediatric Surgery (1998 - present), The College of Surgeons of Hong Kong, 2001.
Tam P.K.H., Member, Co-ordinating Committee in Surgery (1996 - present), Hospital Authority, 2001.
Tam P.K.H., Member, Examination Subcommittee of Licentiate Committee (1997 - 2000), Medical Council of Hong Kong, 2001.
Tam P.K.H., Member, Nominating Committee, Pacific Association of Pediatric Surgeons, 2000.
Tam P.K.H., Member, Publication Committee (2001 - present), Pacific Association of Pediatric Surgeon, 2001.
Tam P.K.H., Member, Research Committee (1998 - 2001), Queen Mary Hospital, 2001.
Tam P.K.H., Overseas Council Member (1999 - present), British Association of Paediatric Surgeons, 2001.
Tam P.K.H., Paediatrics gastrointestinal endoscopy (Invited Lecture), Workshop on Gastrointestinal Endoscopy for Theatre Nurse, Queen Mary Hospital, Hong Kong, March 3, 2001.
Tam P.K.H., Quandom Fellow (1996 - present), Lincoln College, Oxford, 2001.
Tam P.K.H., Reviewer, Annals of Surgery, 2001.
Tam P.K.H., Reviewer, Action Research (United Kingdom), 2001.
Tam P.K.H., Reviewer, Annals of Royal College of Surgeons of England, 2001.
Tam P.K.H., Reviewer, Archives of Disease in Childhood, 2001.
Tam P.K.H., Reviewer, Asian Journal of Surgery, 2001.
Tam P.K.H., Reviewer, British Journal of Surgery, 2001.
Tam P.K.H., Reviewer, Journal of Pediatric Gastroenterology and Nutrition, 2001.
Tam P.K.H., Reviewer, Journal of Pediatric Surgery, 2001.
Tam P.K.H., Reviewer, Lancet, 2001.
Tam P.K.H., Reviewer, Pediatric Surgery International, 2001.
Tam P.K.H., Reviewer, Research Grants Council (Hong Kong), 2001.
Tam P.K.H., Reviewer, Royal College of Surgeons of England (United Kingdom), 2001.
Tam P.K.H., Reviewer, The Wellcome Trust (United Kingdom), 2001.
Tam P.K.H., Reviewer, Transplantation, 2001.
Tam P.K.H., Reviewer, World Journal of Surgery, 2001.
Tam P.K.H., Spokesperson in Paediatric Surgery (1998 - present), Hong Kong Paediatric Society, 2001.
Tam P.K.H., The United Kingdom Childhood Cancer Study: objectives, materials and methods, Bristish Journal of Cancer. 2000, 82: 1073-1102.
Tam P.K.H., The abdominal wall, In: Morris P.J, Wood W.C. (eds), Oxford Textbook of Surgery, 2nd edition. U.K., Oxford University Press, 2000, Chapter 42.8: 2675-2680.
Tam P.K.H., Visiting Professor, Capital University of Medical Science, 2001.
Tam P.K.H., Visiting Professor, Shanghai Second Medical University, 2001.
Van Heurn L.W.E., Cheng W., De Vries B., Saing H., Kootstra G., Tam P.K.H., Associated anomalies in oesophageal atresia in Asians and Europeans, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Zhao H.T., Chan K.L., Chen Q.M., Guo W.H., To J., Tam P.K.H., Comparative study of glutathione-S-transferase isoenzyme, endotoxin and tumour necrosis factor as markers for intestinal ischaemia, 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, 4-8 April, 2001.
Zhou H., Chan K.L., Chu K.M., Tam P.K.H., Intrafamilial spread of Helicobacter pylori: a prospective study using urea breath test, Journal of Pediatric Surgery. 2000, 35: 1672-1675.
Zhou H., Cheng W., Lam K.Y., Chan G.C.F., Khong P.L., Tam P.K.H., Solid cystic papillary tumour of the pancreas, 4th European Congress of Pediatric Surgery , Budapest, Hungary, 3-5 May, 2001.


Researcher : Tian L
Project Title:Novel approach in induction of donor specific tolerance in small bowel transplantation model in rat: a pre-clinical study
Investigator(s):Dr. Tian L. , Prof. Tam P.K.H.
Department:Surgery
Source(s) of Funding:RGC Fundable Projects (Block Grant Funded)
Start Date:May 2000
Abstract:
To provide the service of SBT for these patients in need in this part of world.


List of Research Outputs

Guo W.H., Tian L., Dallmam M., Tam P.K.H., Heterotoic versus orthotopic small bowel transplantation: survival and immunological differences, 34th Annual Meeting of Pacific Association of Pediatric Surgeons, Kyoto, Japan, April 4-8, 2001.
Guo W.H., Tian L., Yuen Z.W., Chan K.L., Wo J.Y.H., Nicholls G., Dallman M., Tam P.K.H., Recipient FK506 pretreatment regimens in rat small bowel transplantation: allograft survival, function, and systemic infection, Journal of Pediatric Surgery. 2000, 35: 1600-1605.
Guo W.H., Tian L., Chan K.L., Dallman M., Tam P.K.H., Role of CD4+ and CD8+ T cells in early and late acute rejection of small bowel allograft, Journal of Pediatric Surgery. 2001, 36(2): 352-356.
Guo W.H., Tian L., Chan K.L., Tam P.K.H., Role of activated helper and cytotoxic T cells in early and late rejection of small bowel allograft, XLVII Annual International Congress of British Association of Paediatric Surgeons, Sorrento, Italy, July 18-21, 2000.
Guo W.H., Tian L., Tam P.K.H., The production of a novel immunosuppressive fusion protein CTLA4-Ig and a study of its immunosuppressive function, 7th Hong Kong International Cancer Congress. 5th Research Postgraduate Symposium, Hong Kong, December 7-9, 2000.


Researcher : Ting ACW
List of Research Outputs

Cheng S.W.K., Ting A.C.W., Wong J., Endovascular stenting of superficial femoral artery stenosis and occlusions: results and risk factor analysis, Cardiovascular Surgery. 2001, 9(2): 133-140.
Ting A.C.W., Taylor D.C., Salvian A.J., Chen J.C.L., Strandberg S., Hsiang Y.N.H., Carotid endarterectomy in octogenerians, Cardiovascular Surgery. 2000, 8(6): 441-445.
Ting A.C.W., Cheng S.W.K., Wong Wu L.H., Cheung G.C.Y., Changes in venous hemodynamics after superficial vein surgery for mixed superficial and deep venous insufficiency, World Journal of Surgery. 2001, 25: 122-125.
Ting A.C.W., Instructor, Advanced Trauma Life Support Course (1999 - present), American College of Surgeons (Hong Kong Chapter), 2001.


Researcher : Tse CW
List of Research Outputs

Chan T.L., Yuen S.T., Ho J.W.C., Chan A.S.Y., Kwan K.Y.M., Chung L.P., Lam P.W.Y., Tse C.W., Leung S.Y., A novel germline 1.8-kb deletion of hMLH1 mimicking alternative splicing: a founder mutation in the Chinese population, Oncogene. 2001, 20: 2976-2981.
Ho J.W.C., Yuen S.T., Chung L.P., Kwan K.Y.M., Chan T.L., Leung S.Y., Chan A.S.Y., Tse C.W., Lam P.W.Y., Luk S.C., Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients, International Journal of Cancer. 2000, 89: 356-360.


Researcher : Wei WI
Project Title:Evaluation of otological and rhinological problems in patients with nasopharyngeal cancer
Investigator(s):Prof. Wei W.I. , Dr. Lau S.K.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:December 1985
Abstract:
To investigate specific problems of hearing and nasal obstructions in patients with nasopharyngeal cancer.


Project Title:Evaluation of otological and rhinological problems in patients with nasopharyngeal cancer
Investigator(s):Prof. Wei W.I. , Dr. Lau S.K.
Department:Surgery
Source(s) of Funding:Medical Faculty Research Grant Fund
Start Date:December 1985
Abstract:
To investigate specific problems of hearing and nasal obstructions in patients with nasopharyngeal cancer.


Project Title:Evaluation of otological and rhinological problems in patients with nasopharyngeal cancer
Investigator(s):Prof. Wei W.I. , Dr. Lau S.K.
Department:Surgery
Source(s) of Funding:Sun Yat Sen Foundation Fund for Medical Research
Start Date:December 1985
Abstract:
To investigate specific problems of hearing and nasal obstructions in patients with nasopharyngeal cancer.


Project Title:Evaluation of otological and rhinological problems in patients with nasopharyngeal cancer
Investigator(s):Prof. Wei W.I. , Dr. Lau S.K.
Department:Surgery
Source(s) of Funding:Wu Chung Medical Research Fund
Start Date:December 1985
Abstract:
To investigate specific problems of hearing and nasal obstructions in patients with nasopharyngeal cancer.


Project Title:Hearing problems in patients suffering from nasopharyngeal carcinoma
Investigator(s):Prof. Wei W.I.
Department:Surgery
Source(s) of Funding:Simon K.Y. Lee Research Fund in Linguistics, Speech and Hearing Sciences
Start Date:December 1989
Abstract:
To evaluate the hearing problems in patients suffering from nasopharyngeal carcinoma after radiotherapy.


Project Title:1. Clinicopathological study of hypopharyngeal cancers. 2. Comparative morphological, morphometric and immunohistochemical studies of the development of primary and secondary malignant lesions of the head and neck
Investigator(s):Prof. Wei W.I. , Prof. White F.H.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1992
Abstract:
To study the route and pattern of spread of hypopharyngeal cancers by detailed study of the pathological specimens and correlate with the clinical progress; to determine whether quantitative histological, ultrastructural and immunological methods can be used to detect differences between normal, primary and secondary malignant hypopharyngeal on oral epithelial lesions of the head and neck.


Project Title:1. Clinicopathological study of hypopharyngeal cancers. 2. Comparative morphological, morphometric and immunohistochemical studies of the development of primary and secondary malignant lesions of the head and neck
Investigator(s):Prof. Wei W.I. , Prof. White F.H.
Department:Surgery
Source(s) of Funding:Sun Yat Sen Foundation Fund for Medical Research
Start Date:July 1992
Abstract:
To study the route and pattern of spread of hypopharyngeal cancers by detailed study of the pathological specimens and correlate with the clinical progress; to determine whether quantitative histological, ultrastructural and immunological methods can be used to detect differences between normal, primary and secondary malignant hypopharyngeal on oral epithelial lesions of the head and neck.


Project Title:Adjuvant therapy for advanced head and neck cancer: a prospective randomized trial with or without oral levamisole and fluorouracil
Investigator(s):Prof. Wei W.I. , Dr. Ng W.F.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1993
Abstract:
To determine the efficacy of adjuvant therapy using oral levamisole and 5 fluorouracil in reducing recurrences and improving survival in patients with head and neck cancer after standard oncological resection; to assess the histological pattern of host response to tumour with or without the effect of levamisole.


Project Title:Speech rehabilitation after total laryngectomy - self help and mutual help
Investigator(s):Prof. Wei W.I. , Miss Ho M.L., Miss Kwok I.C.L., Mr. Ng H.S.
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation Grant
Start Date:July 1998
Completion Date:December 2000
Abstract:
To visit the hospitals and centres in China where total laryngectomy is performed for patients suffering from cancer of the larynx. During the visit, the aim is to introduce to patients the various methods of speech rehabilitation and to show how patients can help each other during the convalescent period.


Project Title:Head and neck surgical course in China - to teach techniques of contemporary operations and patient care for doctors working in underdeveloped areas in China, to the benefit of poor patients suffering from head and neck cancer
Investigator(s):Prof. Wei W.I. , Dr. Fong W.W.Y., Dr. Hui Y., Dr. Lam L.K., Dr. Yue S.W., Dr. Yuen P.W.
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation Grant
Start Date:July 1998
Completion Date:December 2000
Abstract:
To teach the head and neck surgeons in China the currently established methods of managing patients suffering from head and neck cancer and also to introduce the concept of contemporary nursing care for these patients.


List of Research Outputs

Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Liver transplantation is not contraindicated in infancy, Transplantation Proceedings. 2000, 32(7): 2142-2143.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Post liver transplantation stenosis of biliary-enteric anastomoses in infancy: diagnosis and treatment, Transplantation Proceedings. 2000, 32(7): 2233-2234.
Chow L.W.C., Yuen K.Y., Woo P.C.Y., Wei W.I., Clarithromycin attenuates mastectomy - induced acute inflammatory response, Clinical Diagnostic Laboratory Immunology. 2000, 7: 925-931.
Chow V.W.H., Yuen P.W., Lam K.Y., Tsao G.S.W., Ho W.K., Wei W.I., A comparative study of the clinicopathological significance of E-cadherin and catenins (a, b, g) expression in the surgical management of oral tongue carcinoma, Journal of Cancer Research and Clinical Oncology. 2001, 127: 59-63.
Chow V.W.H., Yuen P.W., Lam B.K.Y., Ho W.K., Wei W.I., Prognostic significance of serum p53 protein and p53 antibody in patients with surgical treatment for head and neck squamous cell carcinoma, Head & Neck. 2001, 23: 286-291.
Ho W.K., Hui Y., Wei W.I., Au D.K.K., Correlation of pure tone audiogram result and hearing benefit of tympanoplasty for chronic suppurative otitis media, Annals of Otology, Rhinology and Laryngology. 2000, 109: 381-384.
Ho W.K., Wei W.I., Yuen P.W., Hui Y., Effect of the external nasal dilator on nasal minimal cross-sectional area in Orientals as assessed by acoustic rhinometry, Otolaryngology. 2000, 29(6): 367-370.
Hui Y., Ma K.M., Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Chow C.M., The relationship between the size of neopharynx after laryngectomy and long term swallowing function - an assessment by scintigraphy, Otolaryngology - Head and Neck Surgery. 2001, 124: 225-9.
Kwong D.L.W., Nicholls J.M., Wei W.I., Chua D.T.T., Sham J.S.T., Yuen P.W., Cheng C.K., Yau C.C., Kwong P.W.K., Choy D.T.K., Correlation of endoscopic and histologic findings before and after treatment for nasopharyngeal carcinoma, Head & Neck. 2001, 23(1): 34-41.
Kwong D.L.W., Wei W.I., Cheng C.K., Choy D.T.K., Lo A.T., Wu P.M., Long term results of radioactive gold grain implantation for the treatment of persistent and recurrent nasopharyngeal carcinoma, Cancer. 2001, 91: 1105-1113.
Lam K.Y., Wei W.I., Ng K.W., Lam L.K., Law S.Y.K., Yuen P.W., Wong J., Pharyngolaryngo-oesophagectomy with pharyngogastric anastomosis - a meta analysis, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Lam L.K., Wei W.I., Wong S.Y., Yuen P.W., Li K.H., Improved management of the donor site of free radial forearm flap, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Law S.Y.K., Fok M., Wei W.I., Lam L.K., Tung P.H.M., Chu K.M., Wong J., Thoracoscopic esophageal mobilization for pharyngolaryngoesophagectomy, Annals of Thoracic Surgery. 2000, 70: 418-422.
Li G.K.H., Wei W.I., Lam L.K., Cheng A.K.K., Ho W.K., Yuen P.W., Sham J.S.T., Management of extensive cervical nodal metastasis in nasopharyngeal carcinoma after radiotherapy - a clinicopathologic study, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), American Journal of Transplantation. 2001, 1(Suppl 1): 261:A502.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Qu J.N.Y., Yuen P.W., Ho W.K., Sham J., Wei W.I., Kwong D., Fluorescent endoscopy of nasopharyngeal carcinoma - preliminary study, Lasers of Surgery and Medicine. 2000, 26(5): 432-440.
Qu J.Y., Yuen P.W., Huang Z., Wei W.I., Autofluorescence of nasopharyngeal carcinoma and normal tissue, Proceedings of International Society for Optical Engineering. 2000, 3917: 9-15.
Saing H., Fan S.T., Wei W.I., Chan K.L., Lo C.M., Mya G.H., Tsoi N.S., Yuen K.Y., Ng I.L.O., Chau M.T., Tso W.K., Chan J.F.K., Wong J., Pediatric liver transplantation: the Hong Kong experience, 6th Congress of the Cambodian Surgical Society, Cambodia, October 25-26, 2000.
Saing H., Fan S.T., Chan K.L., Wei W.I., Lo C.M., Mya G.H., Wong J., Portoenterostomy complimented by liver transplantation for biliary atresia: the Queen Mary Hospital, Hong Kong experience, 6th Congress of the Cambodian Surgical Society, October 25-26, 2000.
Wei W.I., Sham J.S.T., Cancer of the Larynx and Hypopharynx. Oxford, United Kingdom, Isis Medical Media, 2000.
Wei W.I., Chief of Service, Department of ENT (November 1997 - present), Queen Mary Hospital, Hong Kong, 2001.
Wei W.I., Wong R., Hui Y., Au D.K.K., Wong Y.K., Ho W.K., Tsang A., Kung P., Chung E., Chinese tonal language rehabilitation following cochlear implantation in children, Acta Oto-laryngologica (Stockh). 2000, 120: 218-221.
Wei W.I., Corresponding Member (1997 - present), American Academy of Otolaryngology - Head and Neck Surgery, 2001.
Wei W.I., Council Member (1993 - present), The College of Surgeons of Hong Kong, 2001.
Wei W.I., Dysphagia, earache, and a neck mass: diagnostic dilemmas, In: Corson J.D. and Williamson R.C.N. (eds.), Surgery. London, Mosby, 2001, 13.2-13.3.
Wei W.I., Examiner (FRCS), Part II Fellowship Examination in Otolaryngology (November 1993 - present), Royal College of Surgeons of Edinburgh, Edinburgh, U.K., 2001.
Wei W.I., Examiner in Surgery, Final Examination, Licentiate Examination Board for Non-Commonwealth Doctors (July 1985 - present), Medical Council of Hong Kong, 2001.
Wei W.I., Expert in the Surgery Specialty (May 2000 - April 2001), Hospital Authority, Hong Kong, 2001.
Wei W.I., External Assessor, Department of Otorhinolaryngology (April 15, 1999 - April 7, 2002), Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia, 2001.
Wei W.I., Fellow (1995 - present), American Laryngological Association, USA, 2001.
Wei W.I., Histologic and scanning electron microscopic study of bile duct healing, Asian Journal of Surgery. 2001, 24(1): 7-10.
Wei W.I., Honorary Advisor (1987 - present), The New Voice Club of Hong Kong, 2001.
Wei W.I., Honorary Advisor (December 1993 - present), Hong Kong Parents' Association of Cleft Lip and Palate Children, Hong Kong, 2001.
Wei W.I., Honorary Advisor (February 1993 - present), Alliance for Patients' Mutual Help Organizations, Hong Kong, 2001.
Wei W.I., Honorary Advisor (February 1995 - present), Kin Lok Club, Hong Kong (Nasopharyngeal Carcinoma Patient Support Group), 2001.
Wei W.I., Honorary Advisor (July 2000 - June 2005), Youth International Enterprise Ltd., Hong Kong. 2001.
Wei W.I., Honorary Clinical Supervisor, Vocational Training Programme in Family Medicine (January 1999 - December 2000), The Hong Kong College of Family Physicians, 2000.
Wei W.I., Honorary Consultant, Department of Surgery (December 1991 - present), Queen Mary Hospital, 2001.
Wei W.I., Honorary Director (December 1997 - present), The First Medical School, West China University of Medical Sciences, Chengdu, China, 2001.
Wei W.I., Honorary Medical Advisor (August 1994 - present), The Cancer Crusade Angels Service Society of Hong Kong, 2001.
Wei W.I., Honorary Member of Editorial Board (1999 - present), Chinese Journal of Cancer, 2001.
Wei W.I., Honorary Reviewer (September 1999 - present)), International Union Against Cancer - ICRETT Grant, 2001.
Wei W.I., Honorary Reviewer, The Hong Kong Practitioner, Journal of Hong Kong College of Family Physicians, Hong Kong, 2001.
Wei W.I., Honorary Reviewer, Cancer, Interdiscipline International Journal of the American Cancer Society, U.S.A., 2001.
Wei W.I., Honorary Reviewer, Head & Neck, Journal for the Sciences and Specialties of the Head and Neck, U.S.A., 2001.
Wei W.I., Honorary Reviewer, Oncology, International Journal of Cancer Research and Treatment, Switzerland, 2001.
Wei W.I., Honorary Senior Consultant (ENT) (April 2000 - present), Tung Wah Hospital, 2001.
Wei W.I., Honoray Advisor (October 1995 - present), Driver Rehabilitation Service, ReHabAid Centre, Hong Kong Polytechnic University, Hong Kong, 2001.
Wei W.I., Management of early carcinoma of the larynx: the Asian perspective (Abstract), ENT News. 2001, 9(2): 18-19.
Wei W.I., Member (30 November 1996 - present), Committee for the Selection of Heads of Teaching Departments, The University of Hong Kong, 2001.
Wei W.I., Member of Editorial Board ( January 1995 - present), Hong Kong Medical Journal, Hong Kong Academy of Medicine, 2001.
Wei W.I., Member of Editorial Board (1996 - present), Chinese Journal of Otolaryngology, 2001.
Wei W.I., Member of Editorial Board (1999 - present), Journal of Clinical Oncology (Chinese version), 2001.
Wei W.I., Member of Editorial Board (January 1997 - present), Journal of Clinical Otorhinolaryngology (China), 2001.
Wei W.I., Member of Editorial Board (June 1995 - present), Australian and New Zealand Journal of Surgery, 2001.
Wei W.I., Member of Editorial Board (May 1997 - present), The Asean ORL Head and Neck Journal, 2001.
Wei W.I., Member of Editorial Board (November 1994 - present), The American Journal of Otolaryngology, 2001.
Wei W.I., Member of Editorial Board (October 1995 - present), Chinese Journal of Clinical Oncology, 2001.
Wei W.I., Member of Editorial Board, (1994 - present), Cutting Edges, The College of Surgeons of Hong Kong Newsletter, 2001.
Wei W.I., Member, Academic Advisory Committee for Diploma Course in Oncology for Health Care Professionals (April 1998 - present), Cancer Centre, Queen Mary Hospital and SPACE, The University of Hong Kong, 2001.
Wei W.I., Member, Professional Standards Review Committee (May 1998 - present), Queen Mary Hospital, Hong Kong, 2001.
Wei W.I., Messages from the HA Hospitals' Chiefs of Service, Queen Mary Hospital and Tung Wah Hospital, Hong Kong Otorhinolaryngological Society 30th Anniversary Memento. 2000, 15.
Wei W.I., National Delegate (1987 - present), Hong Kong Representative, Asian Federation of Laryngectomees Association, 2001.
Wei W.I., Pharynx and cervical esophagus, In: Corson J.D. and Williamson R.C.N. (eds.), Surgery. London, Mosby, 2001, 11.1-11.6.
Wei W.I., President (2000 - present), Hong Kong Head and Neck Society, 2001.
Wei W.I., President, The Hong Kong College of Otorhinolaryngologists, 2001.
Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Wong L.Y., Quality of life in early postoperative period after major resection for head and neck cancer - a prospective study, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Wei W.I., The surgeon's vision of nasopharyngeal carcinoma, Journal of the Hong Kong College of Radiologists. 2000, 3 (Suppl.): 17-20.
Wei W.I., Treasurer (1990 - present), Asian Surgical Association, 2001.
Wong R.K., Chung E., Hui Y., Wong B., Wei W.I., Speech perception and production performance of prelingually deafened adolescents after cochlear implantation, Updates in Cochlear Implantation. Advanced Otorhinolaryngology. 2000, 57: 373-376.
Wong Y.K., Hui Y., Au D.K.K., Wei W.I., Economic evaluation of cochlear implantation, Advances in Otorhinolaryngology. 2000, 57: 377-381.
Yuen P.W., Wei W.I., Lam K.Y., Ho C.M., Chow T.L., Yuen Y.F., A comparison of the prognostic significance of tumor diameter, length, width, thickness, area, volume, and clinicopathological features of oral tongue carcinoma, American Journal of Surgery. 2000, 80: 139-143.
Yuen P.W., Lam K.Y., Choy J.T.H., Ho W.K., Wei W.I., Bcl-2 expression of laryngeal carcinoma, Clinical Otolaryngology and Allied Sciences. 2001, 26(2): 129-33.
Yuen P.W., Lam K.Y., Choy T.H., Ho W.K., Wei W.I., Clinicopathological significance of p53 and p21 expression in the surgical treatment of laryngeal carcinoma, Anticancer Research. 2000, 20: 4863-4866.


Researcher : Wong J
Project Title:A prospective randomized controlled trial on neoadjuvant regional chemotherapy for gastric cancer
Investigator(s):Prof. Wong J. , Dr. Chu K.M., Dr. Leung S.Y., Prof. Ngan H., Dr. Ooi C.G.C., Dr. Yuen S.T.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:November 1996
Abstract:
To undertake the first randomized controlled trial of neoadjuvant regional chemotherapy for gastric cancer.


Project Title:A prospective randomized controlled trial on neoadjuvant regional chemotherapy for gastric cancer
Investigator(s):Prof. Wong J. , Dr. Chu K.M., Dr. Leung S.Y., Prof. Ngan H., Dr. Ooi C.G.C., Dr. Yuen S.T.
Department:Surgery
Source(s) of Funding:Hong Kong Research Grants Council Competitive Earmarked Research Grants
Start Date:November 1996
Abstract:
To undertake the first randomized controlled trial of neoadjuvant regional chemotherapy for gastric cancer.


Project Title:A prospective randomized controlled trial on neoadjuvant regional chemotherapy for gastric cancer
Investigator(s):Prof. Wong J. , Dr. Chu K.M., Dr. Leung S.Y., Prof. Ngan H., Dr. Ooi C.G.C., Dr. Yuen S.T.
Department:Surgery
Source(s) of Funding:RGC Fundable Projects (Block Grant Funded)
Start Date:November 1996
Abstract:
To undertake the first randomized controlled trial of neoadjuvant regional chemotherapy for gastric cancer.


List of Research Outputs

Chan A.O.O., Lam S.K., Chu K.M., Lam C.M., Kwok E.N.L., Leung S.Y., Yuen S.T., Law S.Y., Hui W.M., Lai K.C., Wong B.C.Y., Hu W.C.H., Lai C.L., Wong J., Soluble E-cadherin is a valid prognostic marker in gastric carcinoma., Gut. 2001, 48(6): 808-811.
Chan A.O.O., Lam S.K., Chu K.M., Lam C.M., Kwok E., Leung S.Y., Yuen S.T., Law S.Y.K., Hui W.M., Lai C.L., Wong C.Y., Hu H.C., Lai C.L., Wong J., Soluble E-cadherin is a valid prognostic marker in gastric carcinoma, Gut. 2001, 48: 808-811.
Chan A.O.O., Chu K.M., Yuen S.T., Leung S.Y., Lam S.K., Wong J., Synchronous gastric adenocarcinoma and mucosa-associated tissue lymphoma in association with Helicobacter pylori infection: comparing reported cases between the East and West, American Journal of Gastroenterology. 2001, 96: 1922-1924.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Liver transplantation is not contraindicated in infancy, Transplantation Proceedings. 2000, 32(7): 2142-2143.
Chan K.L., Fan S.T., Saing H., Wei W.I., Lo C.M., Ng I.O.L., Tsoi N.S., Chan J., Tso W.K., Yuen K.Y., Tam P.K.H., Wong J., Post liver transplantation stenosis of biliary-enteric anastomoses in infancy: diagnosis and treatment, Transplantation Proceedings. 2000, 32(7): 2233-2234.
Cheng S.W.K., Ting A.C.W., Wong J., Endovascular stenting of superficial femoral artery stenosis and occlusions: results and risk factor analysis, Cardiovascular Surgery. 2001, 9(2): 133-140.
Cheng S.W.K., Wong J., Vascular surgery in Hong Kong: a review of two decades of development, Asian Journal of Surgery. 2000, 3: 199-202.
Chow V.W.H., Law S.Y.K., Lam K.Y., Luk J.M.C., Wong J., Telomerase activity in small cell esophageal carcinoma, Diseases of the Esophagus. 2001, 14: 139-142.
Chu K.M., Kwok K.F., Law S.Y.K., Wong J., One-week once-daily triple therapy for Helicobacter pylori - a pilot study, Hepatogastroenterology. 2000, 47: 1624-1626.
Fan S.T., Wong J., "No-touch" surgery for hepatobiliary cancer, Scientific News Section, World Gastroenterology News. 2000, Spring: 21-23.
Fan S.T., Wong J., Recurrent pyogenic cholangitis, In: Blumgart L.H. and Fong Y. , Surgery of the Liver and Biliary Tract. London, W.B. Saunders, 2000, volume II; 3rd edition: 1205-1225.
Lam A.K.Y., Law S., Tung P.H.M., Wong J., Esophageal small cell carcinomas - clinicopathologic parameters, p53 overexpression, proliferation marker, and their impact on pathogenesis, Archives of Pathology & Laboratory Medicine. 2000, 124: 228-233.
Lam B.K., Lo C.M., Fung A.S., Fan S.T., Liu C.L., Wong J., Marital adjustment after interspouse living donor liver transplantation, Transplantation Proceedings. 2000, 32: 2095-2096.
Lam K.Y., Wei W.I., Ng K.W., Lam L.K., Law S.Y.K., Yuen P.W., Wong J., Pharyngolaryngo-oesophagectomy with pharyngogastric anastomosis - a meta analysis, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Law S., Wong J., The esophageal anastomosis: the elimination of leakages (Abstract), Pre-Congress Course, XXIII National Congress, Spanish Surgical Association, Madrid, Spain, 2000.
Law S.Y.K., Wong J., A positive oesophageal margin in stomach cancer, The Australian and New Zealand Journal of Surgery. 2000, 70: 697-698.
Law S.Y.K., Wong J., Esophogeal cancer, Current Opinion in Gastroenterology. 2001, 17: 393-399.
Law S.Y.K., Fok M., Wei W.I., Lam L.K., Tung P.H.M., Chu K.M., Wong J., Thoracoscopic esophageal mobilization for pharyngolaryngoesophagectomy, Annals of Thoracic Surgery. 2000, 70: 418-422.
Law S.Y.K., Wong J., Tumours of the oesophagus, In: Tjandra J.J., Clunie G.J.A. and Thomas R.J.S. (eds.), Textbook of Surgery. Australia, Blackwell Science, 2001, 2nd edition: Chapter 14, 103-111.
Law S.Y.K., Wong J., Two-field dissection is enough for esophageal cancer, Diseases of the Esophagus. 2001, 14: 98-103.
Law S.Y.K., Wong J., What is appropriate treatment for carcinoma of the thoracic esophagus?, World Journal of Surgery. 2001, 25: 189-195.
Lee Y.M., Law S.Y.K., Chu K.M., Wong J., Pyloroplasty in gastric replacement of the esophagus after esophagectomy: one-layer or two-layer technique?, Diseases of the Esophagus. 2000, 13: 203-206.
Liu C.L., Fan S.T., Lo C.M., Poon R.T.P., Wong J., Anterior approach for major right hepatic resection for large hepatocellular carcinoma, Annals of Surgery. 2000, 232: 25-31.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), American Journal of Transplantation. 2001, 1(Suppl 1): 261:A502.
Lo C.M., Fan S.T., Liu C.L., Wei W.I., Lai C.L., Yong B.H., Young K., Wong J., Emergency living donor liver transplantation for high-urgency patients (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Lo C.M., Fan S.T., Wong J., Intrahepatic stones, In: Morris P.J. and Wood W.C. (eds.) , Oxford Textbook of Surgery. New York, USA, Oxford University Press Inc., 2000, 2nd edition: 3357-3360.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis., Annas ofl Surgery. 2001, 233(2): 276-281.
Lo C.M., Cheung S.T., Lai C.L., Liu C.L., Ng I.O.L., Yuen M.F., Fan S.T., Wong J., Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis, Annals of Surgery. 2001, 233: 276-281.
Lo C.M., Fan S.T., Liu C.L., Lai C.L., Lau G.K.K., Yong B.H., Ng I.O.L., Young K., Chan J.C.K., Wong J., Liver transplantation in Hong Kong - a wider application., Transplantation Proceedings. 2000, 32(7): 2141.
Lo C.M., Fan S.T., Liu C.L., Lai C.L., Lau G.K.K., Yong B.H., Ng I.O.L., Young K., Chan J.K., Wong J., Liver transplantation in Hong Kong - a wider application, Transplantation Proceedings. 2000, 32: 2141.
Lo C.M., Fan S.T., Liu C.L., Ng I.O.L., Lam B.K., Yong B.H., Lai C.L., Lau G.K.K., Wong J., More effective immunosuppression with the use of FK506 after liver transplantation., Transplantation Proceedings. 2000, 32(7): 2269-2270.
Lo C.M., Fan S.T., Liu C.L., Ng I.O.L., Lam B.K., Yong B.H., Lai C.L., Lau G.K., Wong J., More effective immunosuppression with the use of FK506 after liver transplantation, Transplantation Proceedings. 2000, 32: 2269-2270.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 373:A944.
Lo C.M., Fung J.T.K., Lau G.K.K., Liu C.L., Cheung S.T., Lai C.L., Fan S.T., Wong J., Spontaneous development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B using lamivudine prophylaxis (Abstract), Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Man K., Fan S.T., Lo C.M., Wong J., Graft injury correlated with portal hemodynamics and intra graft endothelin-1 expression in living donor liver transplantaion in relation to graft size (Abstract), The Joint American Transplant Meeting, Chicago, Illinois, USA, May 12-16, 2001.
Man K., Fan S.T., Lo C.M., Wong J., Graft injury correlated with portal hemodynamics and intra graft endothelin-1 expression in living donor liver transplantation in relation to graft size (Abstract), American Journal of Transplantation. 2001, 1 (Suppl 1): 369:A926.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L., Fan S.T., Wong J., Liver transplantation in rats using small-for-size grafts - a study of hemodynamic and morphological changes, Archives of Surgery. 2001, 136: 280-285.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L.F., Fan S.T., Wong J., The mechanism of small-for-size graft injury after liver transplantation, Fourth Shanghai International Symposium on Liver Cancer and Hepatitis and the Second Scientific Meeting of Cheng Si-Yuan (China International) Hepatitis Research Foundation, Pudong, Shanghai, China, September 23-26, 2000.
Man K., Lo C.M., Ng I.O.L., Wong Y.C., Qin L.F., Fan S.T., Wong J., The mechanism of small-for-size graft injury after liver transplantation, Journal of Gastroenterology and Hepatology. 2000, 15: 1139 (O-L-7).
Poon R.T.P., Fan S.T., Yu W.C., Lam B.K.Y., Chan F.Y.S., Wong J., A prospective longitudinal study of quality of life after resection of hepatocellular carcinoma, Archives of Surgery. 2001, 136: 693-699.
Poon R.T.P., Ng I.O.L., Lau C., Fan S.T., Wong J., Clinical and prognostic significance of microvessel density in hepatocellular carcinoma: a prospective study (Abstract), Proceedings of the Angiogenesis and Cancer: From Basic Mechanisms to Therapeutic Applications, Michigan, U.S.A., 2000.
Poon R.T.P., Ng I.O.L., Lau C., Fan S.T., Wong J., Clinical and prognostic significance of microvessel density in hepatocellular carcinoma: a prospective study, Proceedings of American Association for Cancer Research, Traverse City, USA, October 11-15, 2000.
Poon R.T.P., Fan S.T., Wong J., Clinical implications of circulating angiogenic factors in cancer patients (Review Article), Journal of Clinical Oncology. 2001, 19(4): 1207-1225.
Poon R.T.P., Ng I.O.L., Fan S.T., Lai E.C.S., Lo C.M., Liu C.L., Wong J., Clinicopathologic features of long-term survivors and disease-free survivors after resection of hepatocellular carcinoma: a study of a prospective cohort, Journal of Clinical Oncology. 2001, 19(12): 3037-3044.
Poon R.T.P., Fan S.T., Ng I.O.L., Lo C.M., Liu C.L., Wong J., Different risk factors and prognosis of early and late intrahepatic recurrence after resection of hepatocellular carcinoma, Cancer. 2000, 89: 500-507.
Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Ng I.O.L., Wong J., Long-term prognosis after resection of hepatocellular carcinoma associated with hepatitis B-related cirrhosis, Journal of Clinical Oncology. 2000, 18: 1094-1101.
Poon R.T.P., Liu C.L., Lo C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy (Abstract), Digestive Disease Week 2000, San Diego, U.S.A. 2000.
Poon R.T.P., Liu C.L., Lo C.M., Lam C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy, Archives of Surgery. 2001, 136: 11-16.
Poon R.T.P., Fan S.T., Wong J., Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma, Annals of Surgery. 2000, 232: 10-24.
Poon R.T.P., Ng I.O.L., Lau C., Zhu L.X., Yu W.C., Lo C.M., Fan S.T., Wong J., Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: a prospective study, Annals of Surgery. 2001, 233: 227-235.
Saing H., Fan S.T., Wei W.I., Chan K.L., Lo C.M., Mya G.H., Tsoi N.S., Yuen K.Y., Ng I.L.O., Chau M.T., Tso W.K., Chan J.F.K., Wong J., Pediatric liver transplantation: the Hong Kong experience, 6th Congress of the Cambodian Surgical Society, Cambodia, October 25-26, 2000.
Saing H., Fan S.T., Chan K.L., Wei W.I., Lo C.M., Mya G.H., Wong J., Portoenterostomy complimented by liver transplantation for biliary atresia: the Queen Mary Hospital, Hong Kong experience, 6th Congress of the Cambodian Surgical Society, October 25-26, 2000.
Sieh K.M., Chu K.M., Wong J., Intra-abdominal hypertension and abdominal compartment syndrome, Langenbeck's Archives of Surgery. 2001, 386: 53-61.
Siewert J.R., Feith M., Werner M., Stein H.J., Wong J., Adenocarcinoma of the esophagogastric junction - results of surgical therapy based on anatomical/topographic classification in 1,002 consecutive patients - Discussion (Abstract), Annals of Surgery. 2000, 232: 353-361.
Tang C.O., Lam A.K.Y., Law S.Y.K., Wong J., Srivastava G., Detection of genetic alterations in esophageal squamous cell carcinomas and adjacent normal epithelia by comparative DNA fingerprinting using inter-simple sequence repeat PCR1, Clinical Cancer Research. 2001, 7: 1539-1545.
Tang C.O., Wan T.S.K., Wong N., Pang E., Lam A.K.Y., Law S.Y.K., Chow L.M.C., Ma E.S.K., Chan L.C., Wong J., Srivastava G., Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin, Cancer Genetics and Cytogenetics. 2001, 124(1): 36-41.
Tang C.O., Wan T.S.K., Wong N., Pang E., Lam A.K.Y., Law S.Y.K., Chow L.M.C., Ma E.S.K., Chan L.C., Wong J., Srivastava G., Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin, Proceedings at the 7th Hong Kong International Cancer Congress, Hong Kong, 7-9 December. 2000.
Tang J.C.O., Lam K.Y., Law S.Y.K., Wong J., Srivastava G., Detection of genetic alterations in esophageal squamous cell carcinoma tumor specimens and adjacent normal epithelia by comparative DNA fingerprinting using inter-simple sequence repeat PCR (Abstract), 7th Hong Kong International Cancer Congress, 5th Research Postgraduate Symposium, December 2000.
Tang J.C.O., Lam A.K.Y., Law S.Y.K., Wong J., Srivastava G., Detection of genetic alterations in esophageal squamous cell carcinomas and adjacent normal epithelia by comparative DNA fingerprinting using inter-simple sequence repeat PCR, Proceedings at the 7th Hong Kong International Cancer Congress, Hong Kong, 7-9 December. 2000.
Tang J.C.O., Wan T.S.K., Wong N., Pang E., Lam K.Y., Law S.Y.K., Chow L.M.C., Ma E.S.K., Chan L.C., Wong J., Srivastava G., Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin (Abstract), 7th Hong Kong International Cancer Congress, 5th Research Postgraduate Symposium, December 2000.
Tung P.H.M., Law S.Y.K., Chu K.M., Law W.L., Wong J., Gastric rupture after Heimlich manoeuver and cardiopulmonary resuscitation, Hepato-Gastroenterology. 2001, 48: 109-111.
Whooley B.P., Law S.Y.K., Murthy S.C., Alexandrou A., Wong J., Analysis of reduced death and complication rates after esophageal resection, Annals of Surgery. 2001, 233: 338-344.
Whooley B.P., Law S.Y.K., Alexandrou A., Murthy S.C., Wong J., Critical appraisal of the significance of intrathoracic anastomotic leakage after esophagectomy for cancer, The American Journal of Surgery. 2001, 181: 198-203.
Whooley B.P., Wong J., Intrathoracic oesophageal anastomosis: is it worth the risk?, The Australian and New Zealand Journal of Surgery. 2000, 70: 677-680.
Wong J., Adviser (1996 - present), Chinese Society of Vascular Surgery, 2001.
Wong J., Board of Directors (1982 - present), The Hong Kong Tuberculosis, Chest & Heart Diseases Association, 2001.
Wong J., Board of Directors (1991 - present), British Isles Group, James IV Association of Surgeons, 2001.
Wong J., Board of Directors (1997 - present), Australian International School Foundation, Hong Kong, 2001.
Wong J., Chair Professor, Staff Review Committee (1999 - present), Lingnan University, Hong Kong, 2001.
Wong J., Chairman (2000 - present), Advisory Committee, International Society for Digestive Surgery, 2001.
Wong J., Chief of Service, Department of Surgery (1993 - present), Queen Mary Hospital, 2001.
Wong J., Consultant Professor (1995 - present), Shanghai Second Medical University, Shanghai, China, 2001.
Wong J., Corresponding Member (1993 - present), Societa Italiana Di Gastro-enterologia, 2001.
Wong J., Council Member (1986 - present), Shantou University, Shantou, China, 2001.
Wong J., Council Member (1992 - present), The Hong Kong Liver Foundation, 2001.
Wong J., Director (1998 - present), The Hong Kong Digestive Foundation, 2001.
Wong J., East and West - diversity and unity in surgery (Invited Lecture), 118th Congress of the German Socity of Surgery, Munich, Germany, 2001.
Wong J., Law S., Esophageal resection in the new millennium. Does minimally invasive surgery play a role? (Invited Lecture), Digestive Disease Week 2000, San Diego, U.S.A. 2000.
Wong J., Law S.Y.K., Esophageal resection in the new millennium. Does minimally invasive surgery play a role?, Syllabus for SSAT Post-graduate Course, DDW 2000. 2000.
Wong J., Law S.Y.K., Esophagogastrectomy for carcinoma of the esophagus and gastric cardia, and the esophageal anastomosis, In: Baker R.J. and Fischer J.E. (eds.), Mastery of Surgery. Philadelphia, USA, Lippincott Williams & Wilkins, 2001, 4th edition: Chapter 64, 813-827.
Wong J., Executive Committee Member (1992 - present), International Gastro-Surgical Club, 2001.
Wong J., Executive Committee Member (1997 - present), Asian Breast Cancer Society, 2001.
Wong J., External Examiner, Academic Advisory Committee (1997 - present), Diploma Course in Stomal Therapy Nursing, School of Professional and Continuing Education, The University of Hong Kong, 2001.
Wong J., Foundation Fellow (1993 - present), Hong Kong Academy of Medicine, 2001.
Wong J., Honorary Advisor (1994 - present), Hong Kong Council of Enterostomal Therapists, 2001.
Wong J., Honorary Advisor (1999 - present), International Council of Surgical Gastroenterology (ICSG), 2001.
Wong J., Honorary Consultant in Surgery (1994 - present), Kwong Wah Hospital, 2001.
Wong J., Honorary Medical Advisor to the Commissioner for Administrative Complaints (1994 - present), The Govenment of the Hong Kong SAR, Hong Kong, 2001.
Wong J., Honorary Member (1994 - present), The Australian Alumni Association of Hong Kong, 2001.
Wong J., Honorary Professor, Department of Thoracic Surgery (1995 - present), Chinese PLA General Hospital, Beijing, China, 2001.
Wong J., Honorary Senior Consultant in General Surgery (1996 - present), Tung Wah Hospital, Hong Kong, 2001.
Wong J., Invited Lecturer, 86th Clinical Congress, The American College of Surgeons, Chicago, U.S.A , 2000.
Wong J., Invited Lecturer, International Symposium: Standards and Controversies in the Treatment of Carcinoma of the Esophagus and Gastroesophageal Junction, Dusseldorf, Germany, 2000.
Wong J., Invited Lecturer, 17th World Congress, International Society for Digestive Surgery, Hamburg, Germany. September, 2000.
Wong J., Invited Lecturer, 35-year Reunion Conference, Faculty of Medicine, The University of Sydney, Sydney, Australia. January, 2001.
Wong J., Invited Lecturer, 7th Hong Kong International Cancer Congress, Hong Kong, 2000.
Wong J., Invited Lecturer, XXIII National Congress of Surgery, Spanish Surgical Association , Madrid, Spain. November 6-7, 2000.
Wong J., Life Member (1994 - present), Association of Thoracic and Cardiovascular Surgeons of Asia, 2001.
Wong J., Member (1990 - present), Fellow Leadership Society, American College of Surgeons, 2001.
Wong J., Member of Editorial Board, Advances of Surgery, 2001.
Wong J., Member of Editorial Board, Croatian Journal of Gastronenterology and Hepatology, In: , 2001.
Wong J., Member of Editorial Board, Digestive Surgery, 2001.
Wong J., Member of Editorial Board, Hepato-Gastroenterology, 2001.
Wong J., Member of Editorial Board, Italian Journal of Gastroenterology, 2001.
Wong J., Member of Editorial Board, Journal of Clinical Oncology (Chinese edition), 2001.
Wong J., Member of Editorial Board, Journal of Gastroenterology & Hepatology, 2000.
Wong J., Member of Editorial Board, Journal of the American College of Surgeons, 2001.
Wong J., Member of Editorial Board, Web Surgery, 2001.
Wong J., Member of Editorial Board, Chinese Journal of Clinical Oncology, 2001.
Wong J., Member of Editorial Board, Clinics in Surgery and Gastroenterology, 2001.
Wong J., Member of Editorial Board, Current Practice of Surgery, 2001.
Wong J., Member of Editorial Board, Diseases of the Esophagus, 2001.
Wong J., Member of Editorial Board, Illustrated Case Reports in Gastroenterology, 2001.
Wong J., Member of Editorial Board, Journal of the Spanish Surgical Association (Cirugia Espanola), 2001.
Wong J., Member of Editorial Board, Surgery, 2001.
Wong J., Member of Editorial Board, The Australian and New Zealand Journal of Surgery, 2001.
Wong J., Member of Editorial Board, The Journal of Gastrointestinal Surgery, 2001.
Wong J., Member of the Court (2000 - 2001), Lingnan University, Hong Kong, 2001.
Wong J., Member, Academic Advisory Committee (1997 - present), Diploma in Intensive Care Nursing, School of Professional and Continuing Education, The University of Hong Kong, 2001.
Wong J., Member, Academic Advisory Committee (1999 - present), Diploma in Surgical Nursing, School of Professional and Continuing Education, The University of Hong Kong, 2001.
Wong J., Member, Board of Governors (1996 - present), Prince Philip Dental Hospital, Hong Kong, 2001.
Wong J., Member, Central Research Committee (1995 - 2001), International Society for Diseases of the Esophagus, 2001.
Wong J., Member, Committee on Personnel Matters (1995 - present), The University of Hong Kong, 2001.
Wong J., Member, Coordinating Committee in Surgery (1992 - present), Hospital Authority, Hong Kong, In: , 2001.
Wong J., Member, Disciplinary Committee (1997 - present), The University of Hong Kong, 2001.
Wong J., Member, General Purposes Committee (1995 - present), The University of Hong Kong, 2001.
Wong J., Member, Hospital Governing Committee (1991 - present), The Grantham Hospital, Hong Kong, 2001.
Wong J., Member, Hospital Governing Committee (1995 - present), Queen Mary Hospital, Hong Kong, 2001.
Wong J., Member, House Committee (1996 - present), The Grantham Hospital, Hong Kong, 2001.
Wong J., Member, Internship Sub-Committee (1997 - present), The Licentiate Committee of the Medical Council of Hong Kong, 2001.
Wong J., Member, Journal Committee (1995 - 2001), International Society for Diseases of the Esophagus, 2001.
Wong J., Member, Medical Sub-Committee (1995 - 2003), University Grants Committee, Hong Kong, 2001.
Wong J., Member, Professional Standards Review Committee (1996 - present), Queen Mary Hospital, Hong Kong, 2001.
Wong J., Member, Public Relations Committee (1996 - present), The Grantham Hospital, Hong Kong, 2001.
Wong J., National Representative (1998 - 2001), International Society for Diseases of the Esophagus, 2001.
Wong J., Panel of Chairmen, Committee on Academic Review (1999 - present), The University of Hong Kong, 2001.
Wong J., Permanent Scientific Committee Member (1993 - present), International Organization for Statistical Studies on Diseases of the Esophagus (O.E.S.O.), 2001.
Wong J., President (1995 - present), Hong Kong Chapter, American College of Surgeons, 2001.
Wong J., President, Pan-Pacific Surgical Association, 2001.
Wong J., Law S.Y.K., Reconstruction techniques in cancer of the gastroesophageal junction (Invited Lecture), 4th International Gastric Cancer Congress, New York, 2001. S06.
Wong J., Law S., Reconstructive techinques (Invited Lecture), 4th International Congress on Gastric Cancer, New York, U.S.A., 2001.
Wong J., Role for surgeons in training tomorrow's doctors (Invited Lecture), 4th Scientific Congress, University Surgeons of Asia, Singapore, 2000.
Wong J., Towards zero surgical mortality (Invited Lecture), 4th Scientific Congress, University Surgeons of Asia, Singapore, 2000.
Wong J., Law S.Y.K., Transhiatal esophagectomy - Esophagectomy without thoracotomy, In: Baker R.J. and Fischer J.E. (eds.), Mastery of Surgery. Philadelphia, USA, Lippincott Williams & Wilkins, 2001, 4th edition: Chapter 65, 828-836.
Wong J., Trustee (1996 - present), S.K. Yee Medical Foundation, Hong Kong, 2001.
Wong J., Visiting Professor (1996 - present), The Third Hospital, Beijing Medicine University, Beijing, China, 2001.
Wong J., Visiting Professor of General Surgery (1998 - present), Sun Yat-sen University of Medical Sciences, Guangzhou, China, 2001.
Wong J., Law S., Zero operative mortality improves survival (Invited Lecture), The 100th Annual Congress of Japan Surgical Society. 2000.


Researcher : Wong SY
List of Research Outputs

Lam L.K., Wei W.I., Wong S.Y., Yuen P.W., Li K.H., Improved management of the donor site of free radial forearm flap, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Wong S.Y., Chan S.H., Lam L.K., Ng W.M., Li K.H., Chung H.P., Aesthetic considerations in the surgical management of Madelung's disease, 7th International Congress of Oriental Aesthetic Plastic Surgery, Seoul, Korea, October 2000.
Wong S.Y., Council Member (1999 - present), Hong Kong Head & Neck Society, 2001.
Wong S.Y., Secretary, Plastic Surgery Board (1999 - present), Hong Kong Academy of Medicine, 2001.
Wong S.Y., Signs and symptoms of malignant parotid tumours: an objective assessment, Journal of Royal College of Surgeons of Edinburgh. 2001, 46: 91-95.
Wong S.Y., Li J.H.C., The omohyoid sling syndrome, American Journal of Otolaryngology. 2000, 21: 318-322.
Wong S.Y., Li G.K.H., The role of fine-needle aspiration cytology in the management of parotid tumors: a critical clinical appraisal, Head and Neck. 2001, 22: 469-473.
Wong S.Y., Treasurer (1999 - present), Hong Kong Burns Society, 2001.
Wong S.Y., Treasurer (1999 - present), Hong Kong Society for Plastic & Reconstructive Surgeons, 2001.


Researcher : Wong SY
List of Research Outputs

Lam L.K., Wei W.I., Wong S.Y., Yuen P.W., Li K.H., Improved management of the donor site of free radial forearm flap, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Wong S.Y., Chan S.H., Lam L.K., Ng W.M., Li K.H., Chung H.P., Aesthetic considerations in the surgical management of Madelung's disease, 7th International Congress of Oriental Aesthetic Plastic Surgery, Seoul, Korea, October 2000.
Wong S.Y., Council Member (1999 - present), Hong Kong Head & Neck Society, 2001.
Wong S.Y., Secretary, Plastic Surgery Board (1999 - present), Hong Kong Academy of Medicine, 2001.
Wong S.Y., Signs and symptoms of malignant parotid tumours: an objective assessment, Journal of Royal College of Surgeons of Edinburgh. 2001, 46: 91-95.
Wong S.Y., Li J.H.C., The omohyoid sling syndrome, American Journal of Otolaryngology. 2000, 21: 318-322.
Wong S.Y., Li G.K.H., The role of fine-needle aspiration cytology in the management of parotid tumors: a critical clinical appraisal, Head and Neck. 2001, 22: 469-473.
Wong S.Y., Treasurer (1999 - present), Hong Kong Burns Society, 2001.
Wong S.Y., Treasurer (1999 - present), Hong Kong Society for Plastic & Reconstructive Surgeons, 2001.


Researcher : Wong YK
List of Research Outputs

Au D.K.K., Hui Y., Wong Y.K., Comparison of the results of two different implant systems using continuous interleaved sampler speech processing strategy, Advances in Otorhinolaryngology. 2000, 57: 430-434.
Wei W.I., Wong R., Hui Y., Au D.K.K., Wong Y.K., Ho W.K., Tsang A., Kung P., Chung E., Chinese tonal language rehabilitation following cochlear implantation in children, Acta Oto-laryngologica (Stockh). 2000, 120: 218-221.
Wong Y.K., Hui Y., Au D.K.K., Wei W.I., Economic evaluation of cochlear implantation, Advances in Otorhinolaryngology. 2000, 57: 377-381.


Researcher : Wong Wu LH
List of Research Outputs

Ting A.C.W., Cheng S.W.K., Wong Wu L.H., Cheung G.C.Y., Changes in venous hemodynamics after superficial vein surgery for mixed superficial and deep venous insufficiency, World Journal of Surgery. 2001, 25: 122-125.


Researcher : Yeung C
List of Research Outputs

Poon R.T.P., Liu C.L., Lo C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy (Abstract), Digestive Disease Week 2000, San Diego, U.S.A. 2000.
Poon R.T.P., Liu C.L., Lo C.M., Lam C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy, Archives of Surgery. 2001, 136: 11-16.


Researcher : Yu WC
List of Research Outputs

Poon R.T.P., Fan S.T., Yu W.C., Lam B.K.Y., Chan F.Y.S., Wong J., A prospective longitudinal study of quality of life after resection of hepatocellular carcinoma, Archives of Surgery. 2001, 136: 693-699.


Researcher : Yuen PW
Project Title:Mapping of chromosomal abnormality in nasopharyngeal carcinoma by comparative genomic hybridization
Investigator(s):Dr. Yuen P.W. , Prof. Kwong Y.L.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:July 1997
Completion Date:December 2000
Abstract:
To locate the chomosomal abnormality of nasopharyngeal carcinoma for future search for novel oncogene and tumour suppressor gene.


Project Title:The clinicopathological significance of hypermethylation and expression of E-cadherin/catenins in oral tongue carcinoma
Investigator(s):Dr. Yuen P.W.
Department:Surgery
Source(s) of Funding:Block Grant Earmarked for Research
Start Date:November 2000
Abstract:
(1) To evaluate the prognostic significance of downregulation of E-cadhein/catenins adhesion molecules in oral tongue carcinoma. The results may be useful in helping us to design the management plan according to the prognosis. (2) To evaluate the role of hypermethulation in the control of expression of E-cadherin. The study will help us to understand the genetic pathogenesis of abnormal E-cadherin expression in oral cancer.


List of Research Outputs

Chien G., Yuen P.W., Kwong D., Kwong Y.L., Comparative genomic hybridization analysis of nasopharyngeal carcinoma - consistent patterns of genetic aberrations and clinicopathological and correlations., Cancer Genetics and Cytogenetics. 2001, 126(1): 63-7.
Chow V.W.H., Yuen P.W., Lam K.Y., Tsao G.S.W., Ho W.K., Wei W.I., A comparative study of the clinicopathological significance of E-cadherin and catenins (a, b, g) expression in the surgical management of oral tongue carcinoma, Journal of Cancer Research and Clinical Oncology. 2001, 127: 59-63.
Chow V.W.H., Yuen P.W., Lam B.K.Y., Ho W.K., Wei W.I., Prognostic significance of serum p53 protein and p53 antibody in patients with surgical treatment for head and neck squamous cell carcinoma, Head & Neck. 2001, 23: 286-291.
Ho W.K., Wei W.I., Yuen P.W., Hui Y., Effect of the external nasal dilator on nasal minimal cross-sectional area in Orientals as assessed by acoustic rhinometry, Otolaryngology. 2000, 29(6): 367-370.
Hui Y., Ma K.M., Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Chow C.M., The relationship between the size of neopharynx after laryngectomy and long term swallowing function - an assessment by scintigraphy, Otolaryngology - Head and Neck Surgery. 2001, 124: 225-9.
Kwong D.L.W., Nicholls J.M., Wei W.I., Chua D.T.T., Sham J.S.T., Yuen P.W., Cheng C.K., Yau C.C., Kwong P.W.K., Choy D.T.K., Correlation of endoscopic and histologic findings before and after treatment for nasopharyngeal carcinoma, Head & Neck. 2001, 23(1): 34-41.
Lam K.Y., Wei W.I., Ng K.W., Lam L.K., Law S.Y.K., Yuen P.W., Wong J., Pharyngolaryngo-oesophagectomy with pharyngogastric anastomosis - a meta analysis, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Lam L.K., Wei W.I., Wong S.Y., Yuen P.W., Li K.H., Improved management of the donor site of free radial forearm flap, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Li G.K.H., Wei W.I., Lam L.K., Cheng A.K.K., Ho W.K., Yuen P.W., Sham J.S.T., Management of extensive cervical nodal metastasis in nasopharyngeal carcinoma after radiotherapy - a clinicopathologic study, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Lo A.K.F., Yuen P.W., Liu Y., Wang X.H., Cheung A.L.M., Wong Y.C., Tsao S.W., Downregulation of hemidesmosomal proteins in nasopharyngeal carcinoma cells, Cancer Letters. 2001, 163(1): 117-123.
Lo K.F., Yuen P.W., Liu Y., Wang X., Cheung A., Wong Y.C., Tsao G.S.W., Down regulation of hemidesmosomal proteins in nasopharyngeal carinoma cells, Cancer Letters. 2001, 163: 117-124.
Ng I.O.L., Xiao L., Lam A.K.Y., Yuen P.W., Ng M.M.T., Microsatellite alterations in squamous cell carcinoma of the head and neck - clustering of loss of heterozygosity in a distinct subset, Oral Oncology. 2000, 36: 484-490.
Qu J.N.Y., Yuen P.W., Ho W.K., Sham J., Wei W.I., Kwong D., Fluorescent endoscopy of nasopharyngeal carcinoma - preliminary study, Lasers of Surgery and Medicine. 2000, 26(5): 432-440.
Qu J.Y., Yuen P.W., Huang Z., Wei W.I., Autofluorescence of nasopharyngeal carcinoma and normal tissue, Proceedings of International Society for Optical Engineering. 2000, 3917: 9-15.
Wei W.I., Ho W.K., Yuen P.W., Lam L.K., Wong L.Y., Quality of life in early postoperative period after major resection for head and neck cancer - a prospective study, 5th International Conference on Head and Neck Cancer, San Francisco, California, U.S.A., July 29 - August 2, 2000.
Yuen P.W., Wei W.I., Lam K.Y., Ho C.M., Chow T.L., Yuen Y.F., A comparison of the prognostic significance of tumor diameter, length, width, thickness, area, volume, and clinicopathological features of oral tongue carcinoma, American Journal of Surgery. 2000, 80: 139-143.
Yuen P.W., Lam K.Y., Choy J.T.H., Ho W.K., Wei W.I., Bcl-2 expression of laryngeal carcinoma, Clinical Otolaryngology and Allied Sciences. 2001, 26(2): 129-33.
Yuen P.W., Lam K.Y., Choy T.H., Ho W.K., Wei W.I., Clinicopathological significance of p53 and p21 expression in the surgical treatment of laryngeal carcinoma, Anticancer Research. 2000, 20: 4863-4866.
Yuen P.W., Honorary Consultant in Otorhinolaryngology, Department of Surgery (1996 - present), Tung Wah Hospital, Hong Kong, 2001.
Yuen P.W., Member, Education Committee (1996 - present), The Hong Kong College of Otorhinolaryngologists, 2001.
Yuen P.W., Member, Working Group on Hospital Medical Records (1995 - present), Queen Mary Hospital, 2001.


Researcher : Yuen WK
List of Research Outputs

Lau H., Patil N.G., Lee F.C.W., Yuen W.K., A prospective trial of analgesia following endoscopic extraperitoneal inguinal hernioplasty: local wound infiltration versus extraperitoneal instillation of bupivacaine (Abstract), Surgical Endoscopy. 2001, 15 (Suppl.): S142.
Lau H., Patil N.G., Lee F.C.W., Yuen W.K., A prospective trial of analgesia following endoscopic extraperitoneal inguinal hernioplasty: local wound infiltration versus extraperitoneal instillation of bupivacaine, 2001 Annual Meeting, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Missouri, USA, April 18-21, 2001.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Early outcomes of laparoscopic totally extraperitoneal hernia repair versus open mesh hernioplasty, Asian Journal of Surgery. 2000, 23: 244-248.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Laparoscopic totally extraperitoneal inguinal hernioplasty: results of 100 consecutive repairs, Annals of Academy of Medicine, Singapore. 2000, 29: 640-643.
Lau H., Lee F.C.W., Patil N.G., Yuen W.K., Technique for safe placement of re-usable trocars during endoscopic extraperitoneal inguinal hernioplasty, Annals of the College of Surgeons of Hong Kong. 2000, 4: 123-126.
Poon R.T.P., Liu C.L., Lo C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy (Abstract), Digestive Disease Week 2000, San Diego, U.S.A. 2000.
Poon R.T.P., Liu C.L., Lo C.M., Lam C.M., Yuen W.K., Yeung C., Fan S.T., Wong J., Management of gallstone cholangitis in the era of laparoscopic cholecystectomy, Archives of Surgery. 2001, 136: 11-16.
Yuen W.K., Chen Y.B., Fan S.T., 肝臟移植術, 許業珍, 江朝光編. 軍事醫學科學出版社, 2000, 408-417.


Research postgraduate student: CHOW Wing Han, Vivian
MPhil. thesis - Genes Associated with Invasion and Metastasis of Head and Neck Cancer

Research postgraduate student: MOK Bobo Wing Yee

MPhil. thesis - Expression of Gap-Junctional Connexin 31 in Rat Testis



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