DENTAL FACULTY - ENDODONTOLOGY



Researcher : Chang JWW

Project Title:Diagnostic and prognostic markers related to pathogenic bacteria in endodontic lesions of failed cases
Investigator(s):Chang JWW, Seneviratne CJ, Samaranayake LP, Cheung GSP
Department:Dental Faculty
Source(s) of Funding:Small Project Funding
Start Date:04/2011


List of Research Outputs

Li H.N., Chang J.W.W. and Cheung G.S.P., Incidence of dentinal defects after root filling ex vivo by two techniques, ESE Biennial Congress - Brussels 2017.


Researcher : Cheung GSP

Project Title:Stem cells in human dental pulp with irreversible pulpitis and their potential for tissue regeneration
Investigator(s):Cheung GSP, Zhang C, Chang JWW
Department:Dental Faculty
Source(s) of Funding:Small Project Funding
Start Date:03/2011


Project Title:Biomimetic Nano-structured Anti-bacterial Surfaces for Dental Clinical Applications
Investigator(s):Cheung GSP, Tsoi KH
Department:Dental Faculty - Endodontology
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:11/2017


Project Title:Research Output Prize (Faculty of Dentistry)
Investigator(s):Cheung GSP
Department:Dental Faculty - Endodontology
Source(s) of Funding:Research Output Prize (in Faculty)
Start Date:11/2017


Project Title:Biomimetic Nano-structured Anti-bacterial Surfaces for Dental Clinical Applications
Investigator(s):Cheung GSP, Tsoi KH
Department:Dental Faculty - Endodontology
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:12/2017


Project Title:Biomimetic Nano-structured Anti-bacterial Surfaces for Dental Clinical Applications
Investigator(s):Cheung GSP, Tsoi KH
Department:Dental Faculty - Endodontology
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:12/2017


Project Title:Roots Summit 2018 conference; Antibacterial effectiveness of ultrasonic and laser activate irrigations
Investigator(s):Cheung GSP
Department:Dental Faculty - Endodontology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2018
Completion Date:07/2018


List of Research Outputs

Cen R., Wang R. and Cheung G.S.P., Periodontal Blood Flow Protects the Alveolar Bone from Thermal Injury during Thermoplasticized Obturation: A Finite Element Analysis Study, Journal of Endodontics. 2018, 44: 139-144.
Cheung G.S.P., Editorial Board Member, Dentistry Journal. 2017.
Cheung G.S.P., Managing the root canal biofilm: strategy and possibilities, Pusan National University 2018 Research Fair. 2018.
Cheung G.S.P., 《精靈一點》Public Education Series of Faculty of Dentistry, 2018.
Cheung G.S.P., 新年嗑瓜子忌硬碰硬 牙隱裂隨時崩牙, 東方日報 15-02-2018. 2018.
Kwak S.W., Ha J.H., Cheung G.S.P., Kim H.C. and Kim S.K., Effect of the Glide Path Establishment on the Torque Generation to the Files during Instrumentation: An In Vitro Measurement, Journal of Endodontics. 2018, 44: 496-500.
Kwak S.W., Kim S.K., Ha J.H., Cheung G.S.P. and Kim H.C., Effect of the glide-path establishment on the stress generation to the files during instrumentation: in-situ measurement, Pusan National University 2018 Research Fair. 2018.
Li H.N., Chang J.W.W. and Cheung G.S.P., Incidence of dentinal defects after root filling ex vivo by two techniques, ESE Biennial Congress - Brussels 2017.
Neelakantan P., Romero M., Vera J., Daood U., Khan A.U., Yan A. and Cheung G.S.P., Biofilms in Endodontics—Current Status and Future Directions, International Journal of Molecular Sciences. 2017, 18: 1748.
Neelakantan P., Feroz Khan K.K., Ng P.H., Chui Y.Y., Zhang C. and Cheung G.S.P., Does the Orifice-directed Dentin Conservation Access Design Debride Pulp Chamber and Mesial Root Canal Systems of Mandibular Molars Similar to a Traditional Access Design?, Journal of Endodontics. 2018, 44: 274-279.
Seghayer I. and Cheung G.S.P., Antibacterial effectiveness of ultrasonic and laser activated irrigations, Root Summit 2018 Global Discussion Forum. 2018.
She M.C., Chen N.N. and Cheung G.S.P., Clinical outcomes of teeth treated endodontically through pre-existing crowns, International Endodontic Journal. 2018, 50: 3-56.
Tsui K.H., Li X., Tsoi K.H., Leung S.F., Lei T., Chan W.Y., Zhang C., Chen J., Cheung G.S.P. and Fan Z., Low-cost, flexible, disinfectant-free and regular-array three-dimensional nanopyramid antibacterial films for clinical applications, Nanoscale. 2018, 10: 10436-10442.


Researcher : Chow TW

Project Title:Oral rehabilitation of edentulous patients with osseointegrated implant-supported complete dentures
Investigator(s):Chow TW, Chu CSF, Cheung LK, Chai YCJ
Department:Dental Faculty
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2007


List of Research Outputs

Leung C.K.K., Pow E.H.N., Li K.L.T., Lo E.C.M. and Chow T.W., Accuracy of radiographic measurements for implant planning using cone-beam and helical computer tomography, J Invest Clin Dent. 2017, 8: e12232.


Researcher : Dissanayaka WL

Project Title:In vitro stabilization of HIF-1α signalling to enhance angiogenesis for dental pulp regeneration
Investigator(s):Dissanayaka WL, Zhang C, Jung HS
Department:Dental Faculty - Applied Oral Sciences
Source(s) of Funding:Seed Fund for Basic Research for New Staff
Start Date:06/2017


Project Title:Enhancing post-implantation dental stem cell survival and angiogenesis via in vitro stabilization of HIF-1α signaling
Investigator(s):Dissanayaka WL, Zhang C
Department:Dental Faculty - Applied Oral Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2017


List of Research Outputs

Dissanayaka W.L. and Zhang C., The Role of Vasculature Engineering in Dental Pulp Regeneration, Journal of Endodontics. 2017, 43: S102-S106.


Researcher : Feroz Khan KK

List of Research Outputs

Neelakantan P., Feroz Khan K.K., Ng P.H., Chui Y.Y., Zhang C. and Cheung G.S.P., Does the Orifice-directed Dentin Conservation Access Design Debride Pulp Chamber and Mesial Root Canal Systems of Mandibular Molars Similar to a Traditional Access Design?, Journal of Endodontics. 2018, 44: 274-279.


Researcher : GONG T

List of Research Outputs

Heng B.C.A., GONG T., XU J., Lim L.W. and Zhang C., EphrinB2 signalling modulates the neural differentiation of human dental pulp stem cells, Biomedical Reports. 2018.
XU J., GONG T., WANG Y.Y., ZOU T., Heng B.C.A., Yang Y. and Zhang C., Inhibition of TGF-β Signaling in SHED Enhances Endothelial Differentiation, Journal of Dental Research. 2018, 97(2): 218-225.


Researcher : Heng BCA

List of Research Outputs

Heng B.C.A., GONG T., XU J., Lim L.W. and Zhang C., EphrinB2 signalling modulates the neural differentiation of human dental pulp stem cells, Biomedical Reports. 2018.
XU J., GONG T., WANG Y.Y., ZOU T., Heng B.C.A., Yang Y. and Zhang C., Inhibition of TGF-β Signaling in SHED Enhances Endothelial Differentiation, Journal of Dental Research. 2018, 97(2): 218-225.
Xiong S., Zhang X., Lu P., Wu Y., Wang Q., Sun H., Heng B.C.A., Bunpetch V., Zhang S. and Ouyang H., A Gelatin-sulfonated Silk Composite Scaffold based on 3D Printing Technology Enhances Skin Regeneration by Stimulating Epidermal Growth and Dermal Neovascularization, Scientific Reports. 2017, 7.


Researcher : Li X

List of Research Outputs

Tsui K.H., Li X., Tsoi K.H., Leung S.F., Lei T., Chan W.Y., Zhang C., Chen J., Cheung G.S.P. and Fan Z., Low-cost, flexible, disinfectant-free and regular-array three-dimensional nanopyramid antibacterial films for clinical applications, Nanoscale. 2018, 10: 10436-10442.


Researcher : Neelakantan P

Project Title:Synthesis and characterization of curcumin nanoparticles with and without novel polymer caging
Investigator(s):Neelakantan P, Cheung GSP, Matinlinna JP, Wang Y
Department:Dental Faculty - Endodontology
Source(s) of Funding:Seed Fund for Basic Research for New Staff
Start Date:04/2017
Completion Date:06/2018


Project Title:Stabilizing the Resin - Dentin Interface of Root Canals Using a Novel Approach
Investigator(s):Neelakantan P, Yiu CKY, Matinlinna JP
Department:Dental Faculty - Endodontology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2018


Project Title:American Association of Endodontists Annual Session 2018; Disruption of Enterococcus faecalis Biofilm by a Novel Green Synthesized Graphene oxide-Silver Nanocomposite
Investigator(s):Neelakantan P
Department:Dental Faculty - Endodontology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2018
Completion Date:04/2018


List of Research Outputs

Ahmed H.M.A., Neelakantan P. and Dummer P.M.H., A new system for classifying accessory canal morphology, International Endodontic Journal. 2017.
Daood U., Banday N., Akram Z., Tsoi K.H., Neelakantan P., Omar H., Abduljabbar T., Vohra F., A;-Hamoudi N. and Fawzy A.S., Mechanical and Spectroscopic Analysis of Retrieved/Failed Dental Implants, Coatings. MDPI, 2017, 7: 201.
Izaz S., Dasari B., Bolla N. and Neelakantan P., Unusual root canal morphology of mandibular first premolar and its management: A rare case report, Journal of Conservative Dentistry. 2018, 21: 344.
Mohan G., Jgannathan N. and Neelakantan P., Histobacteriology Of Teeth With Failed Root Canal Treatment – A Pilot Study, Oral Health. 2017.
Nagendrababu V., Jayaraman J., Suresh A., Kalyanasundaram S. and Neelakantan P., Effectiveness of ultrasonically activated irrigation on root canal disinfection: a systematic review of in vitro studies, Clinical Oral Investigations. 2018, 22: 655-670.
Nagendrababu V., Sheriff Sultan O., Kannathasan S., Patel A.S., Chitra E., Neelakantan P. and Davamani F., Root canal irrigants influence the hydrophobicity and adherence of Staphylococcus epidermidis to root canal dentin: an in vitro study , Restorative Dentistry & Endodontics. 2017, 43.
Neelakantan P., Romero M., Vera J., Daood U., Khan A.U., Yan A. and Cheung G.S.P., Biofilms in Endodontics—Current Status and Future Directions, International Journal of Molecular Sciences. 2017, 18: 1748.
Neelakantan P., Feroz Khan K.K., Ng P.H., Chui Y.Y., Zhang C. and Cheung G.S.P., Does the Orifice-directed Dentin Conservation Access Design Debride Pulp Chamber and Mesial Root Canal Systems of Mandibular Molars Similar to a Traditional Access Design?, Journal of Endodontics. 2018, 44: 274-279.
Neelakantan P., Sriraman P. and Gutmann J.L., Removal of calcium hydroxide intracanal medicament by different irrigants and irrigating techniques: a cone beam computed tomography analysis., General Dentistry. 2017, 65: 45-49.
Neelakantan P., Root canal debridement – Limited by Challenges and Challenging the Limits, AEEDC INTERNATIONAL CONGRESS AND EXHIBITION, DUBAI. 2018.
Neelakantan P., Root canal debridement – Limited by Challenges and Challenging the Limits, Indian Dental Conference. 2018.
Neelakantan P., Teaching Feedback award (Student-led teaching and learning award), The University of Hong Kong. 2018.
Neelakantan P., Undergraduate exchange program, 31 July - 4 August 2017, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China. 2017.
Ounsi H.F., Nassif W., Grandini S., Salameh Z., Neelakantan P. and Anil S., Evolution of Nickel-titanium Alloys in Endodontics., Journal of Contemporary Dental Practice. 2017, 18: 1090-1096.
Reddy P., Neelakantan P., Sanjeev K. and Matinlinna J.P., Effect of irrigant neutralizing reducing agents on the compromised dislocation resistance of an epoxy resin and a methacrylate resin-based root canal sealer in vitro, International Journal of Adhesion and Adhesives. 2018, 82: 206-210.
Thakur B., Pawar A.M., Kfir A. and Neelakantan P., Extrusion of Debris from Primary Molar Root Canals following Instrumentation with Traditional and New File Systems., Journal of Contemporary Dental Practice. 2017, 18: 1040-1044.
Zhezhen X., Zhongchun T., Neelakantan P., Yanling C. and Xi W., Enterococcus faecalis Immunoregulates Osteoclastogenesis of Macrophages, Experimental Cell Research. 2017.


Researcher : XU J

List of Research Outputs

Heng B.C.A., GONG T., XU J., Lim L.W. and Zhang C., EphrinB2 signalling modulates the neural differentiation of human dental pulp stem cells, Biomedical Reports. 2018.
XU J., GONG T., WANG Y.Y., ZOU T., Heng B.C.A., Yang Y. and Zhang C., Inhibition of TGF-β Signaling in SHED Enhances Endothelial Differentiation, Journal of Dental Research. 2018, 97(2): 218-225.


Researcher : ZOU T

List of Research Outputs

XU J., GONG T., WANG Y.Y., ZOU T., Heng B.C.A., Yang Y. and Zhang C., Inhibition of TGF-β Signaling in SHED Enhances Endothelial Differentiation, Journal of Dental Research. 2018, 97(2): 218-225.


Researcher : Zhang C

Project Title:Prevascularized periodontal ligament cell sheet with endothelial cells promotes periodontal tissue complex regeneration
Investigator(s):Zhang C, Chu CH
Department:Dental Faculty - Endodontology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2012


Project Title:Bcl-2 and cMyc gene-transfected dental pulp stem cells outcompete bone marrow-derived cells in dental pulp regeneration
Investigator(s):Zhang C, Cheung GSP, Chang JWW
Department:Dental Faculty - Endodontology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2013


Project Title:EphrinB2 enhances angiogenesis and anastomosis of bioengineered prevascularized dental pulp construct
Investigator(s):Zhang C, Cheung GSP, Jin L, Green DW
Department:Dental Faculty - Endodontology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015
Completion Date:12/2017


Project Title:EphrinB2 and VEGF cooperatively regulate dental pulp stem cell functions and blood vessel formation
Investigator(s):Zhang C, Jin L, Cheung GSP
Department:Dental Faculty - Endodontology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2015


Project Title:Bcl-2 overexpression in human DPSCs promotes angiogenesis through VEGF and HIF-1α activity
Investigator(s):Zhang C, Dissanayaka WL
Department:Dental Faculty - Endodontology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016
Completion Date:03/2018


Project Title:Research Output Prize (Faculty of Dentistry)
Investigator(s):Zhang C, Dissanayaka WL
Department:Dental Faculty - Endodontology
Source(s) of Funding:Research Output Prize (in Faculty)
Start Date:11/2016


Project Title:Functional properties of endothelial and vascular smooth muscle cells derived from stem cells of human exfoliated deciduous teeth (SHED)
Investigator(s):Zhang C, Dissanayaka WL, Heng BCA
Department:Dental Faculty - Endodontology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


Project Title:Engineered tissue constructs with inbuilt perfusable microchannel networks for dental pulp regeneration
Investigator(s):Zhang C, Dissanayaka WL, Jin L, Heng BCA
Department:Dental Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2018


Project Title:Small molecule-based reprogramming of Gingival Mesenchymal Stem Cells into the neural lineage for therapeutic applications
Investigator(s):Zhang C, Heng BCA, Lim LW
Department:Dental Faculty - Endodontology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2018


Project Title:Direct reprogramming of dental stem cells into endothelial cells by overexpressing ETS transcription factor ETV2
Investigator(s):Zhang C, Dissanayaka WL
Department:Dental Faculty - Endodontology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2018


Project Title:HKU Overseas Fellowship Awards 2018-19
Investigator(s):Zhang C
Department:Dental Faculty - Endodontology
Source(s) of Funding:HKU Overseas Fellowship Awards
Start Date:06/2018


List of Research Outputs

CHOPRA H., LIAO C., Zhang C. and Pow E.H.N., Lapine periodontal ligament stem cells for musculoskeletal research in preclinical animal trials, Journal of Translational Medicine. 2018, 16: 1-14.
Dissanayaka W.L. and Zhang C., The Role of Vasculature Engineering in Dental Pulp Regeneration, Journal of Endodontics. 2017, 43: S102-S106.
Heng B.C.A., GONG T., XU J., Lim L.W. and Zhang C., EphrinB2 signalling modulates the neural differentiation of human dental pulp stem cells, Biomedical Reports. 2018.
LI M., Zhang C., Jin L., Matsuo K. and Yang Y., Porphyromonas gingivalis lipopolysaccharide regulates ephrin/Eph signalling in human periodontal ligament fibroblasts , Journal of Periodontal Research. 2017, 52: 913-921.
LI X., Luo W., Ng T.C., Leung P.C., Zhang C., Leung C.F.K. and Jin L., Nanoparticle-encapsulated baicalein markedly modulates pro-inflammatory response in gingival epithelial cells, Nanoscale. 2017, 9: 12897-12907.
LIAO C., Zhang C., Jin L. and Yang Y., Bidirectional regulation by Interleukin-17 in osteogenesis and osteoclastogenesis., 2017 Faculty Annual Scientific Meeting. Faculty of Dentistry, The University of Hong Kong, Hong Kong, Dec 14, 2017.
LIAO C., Zhang C., Jin L. and Yang Y., IL-17A and shear stress modulate osteoclastogenesis/osteogenesis in bone cells, Journal of Dental Research. 2017, 96 (Spec Iss A): 1894.
LIAO C., Zhang C., Jin L. and Yang Y., Role of Interleukin-17 in bone modelling. Invited speech, 2017 China International Orthodontic Conference and the 16th Annual Meeting of Chinese Orthodontic Society, Sept 17-21, 2017, Shanghai, China. 2017.
LIAO C., Cheng T., WANG S., Zhang C., Jin L. and Yang Y., Shear stress inhibits IL-17A-mediated induction of osteoclastogenesis via osteocyte pathways, Bone. 2017, 101: 10-20.
Li X., LI X., WANG S., Leung C.F.K., Zhang C. and Jin L., Infiltration and Profiles of Mesoporous Silica Nanoparticles in Dentinal Tubules, ACS Biomaterials Science & Engineering. 2018, 4: 1428-1436.
Neelakantan P., Feroz Khan K.K., Ng P.H., Chui Y.Y., Zhang C. and Cheung G.S.P., Does the Orifice-directed Dentin Conservation Access Design Debride Pulp Chamber and Mesial Root Canal Systems of Mandibular Molars Similar to a Traditional Access Design?, Journal of Endodontics. 2018, 44: 274-279.
Tsui K.H., Li X., Tsoi K.H., Leung S.F., Lei T., Chan W.Y., Zhang C., Chen J., Cheung G.S.P. and Fan Z., Low-cost, flexible, disinfectant-free and regular-array three-dimensional nanopyramid antibacterial films for clinical applications, Nanoscale. 2018, 10: 10436-10442.
XU J., GONG T., WANG Y.Y., ZOU T., Heng B.C.A., Yang Y. and Zhang C., Inhibition of TGF-β Signaling in SHED Enhances Endothelial Differentiation, Journal of Dental Research. 2018, 97(2): 218-225.
Zhang C., 28th SEAADE & 31st International Association of Dental Research South East Asian Division Annual Meeting, Taipei, Taiwan, 10 - 13 August , 2017 IADR-SEA Division and SEAADE. 2017.
Zhang C., 47th Annual Meeting & Exhibition of the AADR and 42nd Annual Meeting of the CADR, Fort Lauderdale, USA,19-26 March 2018, AADR/CADR, USA. 2018.
Zhang C., Americian Association of Endodontists Annual Conference, Denver, USA, 24-29 April 2018, AAE, USA. 2018.
Zhang C., Chair a session of the academic lectures, 25-27 August 2017, Tianjin Stomatological Hospital,Tianjin, China. 2017.
Zhang C., Clinical applications of regenerative endodontics, 14 September 2017, Faculty of Dentistry, The Univeristy of Hong Kong, Hong Kong, 2017.
Zhang C., Diagnosis and management of vertical root fractures, 12 September 2017, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China. 2017.
Zhang C., Multidisciplinary cross-cutting oral aesthetics, 15-16 July 2017 Shenzhen Longgang E.N.T. Hospital, Shenzhen, China, Endodontic Continuing Training Course. 2017.
Zhang C., New theory and technology of modern root canal therapy, Shenzhen, China, 10-11 March 2018, 2018.
Zhang C., New theory and technology of modern root canal therapy, Xiamen, China, 5-6 May 2018, 2018.
Zhang C., Penn Stem Cell and Regenerative Dentistry Conference, Philadelphia, USA, 20 - 21 October 2017, Penn Dental Medicine, University of Pennsylvania, USA. 2017.
Zhang C., Pulp regeneration and vital pulp therapy, and microscopic endodontic treatment , 29th Malaysian Endodontic Society Annual Scientific Conference and Annual General Meeting, Kuala Lumpur, Malaysia, 25 - 26 November, 2017. 2017.
Zhang C., Several questions worthy to be discussed of root canal therapy, 6 August 2017, Microscopic root canal therapy and new progress of nickel-titanim instrument conference, Zhengzhou Stomatologic Hospital, Zhengzhou, China. 2017.
Zhang C., Standardization construction in clinical teaching process of stomatology, 28-29 July 2017, Nanjing Medical University, Nanjing, China. 2017.
Zhang C., The 23rd China International Exhibition & Scientific Conference, Beijing, China, 9-12 June 2018. 2018.
Zhang C., The 5th Academic Conference of Society of Cariology and Endodontology,Shaanxi Stomatological Association, Yan'an, China, 12-14 October 2017. 2017.
Zhang C., The precise control of root canal preparation and obturation, Xi'an & Shenyang China, 20 & 22 May 2018, 2018.
Zhang C., The precise control of root canal preparation, Chengdu, China, 28 October 2017, A lecture on root canal therapy. 2017.
Zhang C., The precise control of root canal preparation, Hangzhou, China, 7 April 2018, A lecture on root canal therapy. 2018.
Zhang C., The precise control of root canal preparation, Jinan, China, 4 November 2017, A lecture on root canal therapy. 2017.
Zhang C., The precise control of root canal preparation, Nanning, China, 18 November 2017, A lecture on root canal therapy. 2017.
Zhang C., The precise control of root canal preparation, Qingdao, China, 1 April 2018, A lecture on root canal therapy. 2018.
Zhang C., The precise control of root canal preparation, Shenzhen & Guangzhou, China, 21-22 August 2017, A lecture on root canal therapy. 2017.
Zhang C., The role of pre-vascularization in pulp regeneration, 7 - 9 December, 2017 IADR Chinese Division Annual Meeting, Annual Conference of Fujian Stomatological Association, and Geriatric Dentistry Professional Board of Chinese Stomatological Association Annual Meeting. 2017.
Zhang J., Zhang C. and Chu C.H., cAMP signaling up-regulates odonto/osteogenic differentiation of apical papilla-derived stem cells, IADR-SEA. 2017, S0126.


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