DENTAL FACULTY - PERIODONTOLOGY



Researcher : Cheng T

Project Title:Crosstalk of Porphyromonas gingivalis and Helicobacter pylori with human gastric and gingival epithelial cells in molecular signaling
Investigator(s):Cheng T, Jin L, Sun H
Department:Dental Faculty - Periodontology
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:08/2016


Project Title:Doris Zimmern HKU-Cambridge Hughes Hall Fellowships 2015-16
Investigator(s):Cheng T
Department:Dental Faculty - Periodontology
Source(s) of Funding:Doris Zimmern HKU-Cambridge Hughes Hall Fellowships
Start Date:09/2015




Researcher : Corbet EF

Project Title:Effects of periodontal therapy on the control of hypertension
Investigator(s):Corbet EF, Lai SML
Department:Dental Faculty
Source(s) of Funding:Small Project Funding
Start Date:02/2009


List of Research Outputs

Goh V., Corbet E.F. and Leung W.K., Impact of dentine hypersensitivity on oral health-related quality of life in individuals receiving supportive periodontal care, Journal of Clinical Periodontology. 2016, 43: 595-602.
Goh V., Hackmack P.P., Corbet E.F. and Leung W.K., Moderate- to long-term periodontal outcomes of subjects failing to complete a course of periodontal therapy, Australian Dental Journal. 2017, 62: 152-160.
Zee K.-.Y., Chan P.S., Ho J.C.S., Lai S.M.L., Corbet E.F. and Leung W.K., Adjunctive use of modified Yunu-Jian in the non-surgical treatment of male smokers with chronic periodontitis: a randomized double-blind, placebo-controlled clinical trial, Chinese Medicine. 2016, 11: 40.


Researcher : HERATH MUDIYANSELAGE TDKH

List of Research Outputs

HERATH MUDIYANSELAGE T.D.K.H., Darveau R.P., Seneviratne C.J., Wang C.-.Y., Wang Y. and Jin L., Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts, Scientific Reports. 2016, 6: 29829.


Researcher : Ho KL

Project Title:Applications of Photodynamic Therapy on management of Drug Influenced Gingival Enlargement: A Preliminary Double-blinded Randomized Clinical Controlled Trial.
Investigator(s):Ho KL, Leung WK, Chan DTM
Department:Dental Faculty - Periodontology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2015


List of Research Outputs

CHAN C.K., Ho K.L., Lai S.M.L., Lam K.F. and Wong M.C.M., Tooth loss in patients undergoing supportive periodontal maintenance care, Journal of Dental Research. 2017, 96 (Spec Iss A): 1597.
Duangthip D., Leung K.C.M., Ho K.L., Lo E.C.M. and Chu C.H., Oral-health status of Chinese elders with dementia: a pilot study. [Abstract] , IADR. 2017, 96 (Spec Iss A): IP-3674.
Ho K.L., Revision of Crown Lengthening Surgery, Hong Kong Dental Association - The University of Hong Kong Dental Alumni Association. 2016.


Researcher : Jin L

Project Title:Research Output Prize (Faculty of Dentistry)
Investigator(s):Jin L
Department:Dental Faculty
Source(s) of Funding:Research Output Prize (in Faculty)
Start Date:12/2010


Project Title:Novel antifungal small molecule for multi-drug resistant Candida: anti-biofilm activity, in vivo efficacy and cellular targets
Investigator(s):Jin L, Kao RYT, Wang Y, Seneviratne CJ, Samaranayake LP
Department:Dental Faculty - Periodontology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:10/2012
Completion Date:10/2016


Project Title:Crosstalk of human gingival/oral epithelial cells and monocytes with P. gingivalis/P. gingivalis DNA: Epigenetic regulation and molecular signaling
Investigator(s):Jin L, Seneviratne CJ
Department:Dental Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014
Completion Date:12/2016


Project Title:The interactions of P. gingivalis persisters with human oral epithelial cells and monocytes: Molecular profiling and regulating mechanisms
Investigator(s):Jin L, Seneviratne CJ
Department:Dental Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2016


Project Title:The 3rd International Conference on Porphyromonas gingivalis and Related Species in Oral and Systemic Diseases (PgMelbourne2017) ; Mesoporous Silica Nanoparticle-Encapsulated Scutellaria baicalensis as a Promising Immuno-inflammatory Modulator for Periodontal Care
Investigator(s):Jin L
Department:Dental Faculty - Periodontology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2017
Completion Date:05/2017


List of Research Outputs

AB MALIK N.B., Yatim S.M., Lam O.L.T., Jin L. and McGrath C.P.J., Effectiveness of a web-based health education program to promote oral hygiene care among stroke survivors: randomized controlled trial, Journal of Medical Internet Research. 2017, 19(3): e87.
AB MALIK N.B., ZHANG J., Lam O.L.T., Jin L. and McGrath C.P.J., Effectiveness of computer-aided learning in oral health among patients and caregivers: a systematic review, Journal of the American Medical Informatics Association. 2017, 24(1): 209-217.
AB MALIK N.B., Yatim S.M., Lam O.L.T., Jin L. and McGrath C.P.J., Oral care practices among stroke carers – A cross-sectional study, 10th National Conference for Clinical Research (NCCR 2016). 2016.
Ding P.-.H., Darveau R.P., Wang C.-.Y. and Jin L., LPS-binding protein and its interactions with P. gingivalis LPS modulate pro-inflammatory response and Toll-like receptor signaling in human oral keratinocytes, PLOS ONE. 2017, 12: e0173223.
HERATH MUDIYANSELAGE T.D.K.H., Darveau R.P., Seneviratne C.J., Wang C.-.Y., Wang Y. and Jin L., Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts, Scientific Reports. 2016, 6: 29829.
JIANG S., Gao X., Jin L. and Lo E.C.M., Salivary Microbiome Diversity in Caries-Free and Caries-Affected Children, International Journal of Molecular Sciences. 2016, 17: 1978.
Jin L., Award for Professional Exchange & Collaboration, Celebration of the 20th Anniversary of CSA, Chinese Stomatological Association (CSA), September, 2016. 2016.
Jin L., Lamster I.B., Greenspan J.S., Pitts N.B., Scully C. and Warnakulasuriya S., Global burden of oral diseases: emerging concepts, management and interplay with systemic health, Oral Diseases. 2016, 22: 609-619.
LAN X., LI X., Shen F., Jin L. and Su Y., Enhanced anti-cancer effect of lipid-coated cisplatin nanoparticles on HNSCC, Journal of Dental Research. 2017, 96 (Spec Iss A): 3990.
LI P., Fung E.Y.M., Yin X., Seneviratne C.J., Che C.M. and Jin L., The proteomic profiling and hemin-dependent survival mechanisms of Porphyromonas gingivalis persisters, PgMelbourne2017: the 3rd International Conference on Porphyromonas gingivalis and Related Species in Oral and Systemic Diseases, May 14-16, 2017, Melbourne, Australia. 2017.
LI X., Pang K.Y., Ng T.W., Leung P.C., Zhang C., Leung K.C.F. and Jin L., Cellular Interactions and Formation of an Epithelial “Nanocoating-Like Barrier” with Mesoporous Silica Nanoparticles, Nanomaterials. 2016, 6: 192.
LI X., Luo W., Ng T.W., Leung P.C., Zhang C., Leung K.C.F. and Jin L., Mesoporous silica nanoparticle-encapsulated Scutellaria baicalensis as a promising immuno-inflammatory modulator for periodontal care, PgMelbourne2017: the 3rd International Conference on Porphyromonas gingivalis and Related Species in Oral and Systemic Diseases, May 14-16, 2017, Melbourne, Australia. 2017.
LIAO C., Zhang C., Jin L. and Yang Y., IL-17A and shear stress modulate osteoclastogenesis/osteogenesis in bone cells. , The 95th General Session of the International Association for Dental Research, San Francisco, USA, March 22-25, 2017.. 2017.
Liu F., Pelekos G. and Jin L., The gingival biotype in a cohort of Chinese subjects with and without history of periodontal disease, Journal of Dental Research. 2017, 96 (Spec Iss A): 3480.
Panduwawala Kankanamalage C.P.P., Zhan X., Dissanayaka W.L., Samaranayake L.P., Jin L. and Zhang C., In vivo periodontal tissue regeneration by periodontal ligament stem cells and endothelial cells in three-dimensional cell sheet constructs , Journal of Periodontal Research. 2017, 52: 408-418.
REN C., McGrath C.P.J., Jin L., Zhang C. and Yang Y., Effect of diode low-level lasers on fibroblasts derived from human periodontal tissue: a systematic review of in vitro studies., Lasers in Medical Science. 2016, 31: 1493-1510.
REN C., McGrath C.P.J., Jin L., Zhang C. and Yang Y., The effectiveness of low-level laser therapy as an adjunct to non-surgical periodontal treatment: a meta-analysis., Journal of Periodontal Research. 2017, 52: 8-20.
Seneviratne C.J., Samaranayake L.P., Ohshima T., Maeda N. and Jin L., Identification of antifungal molecules from novel probiotic Lactobacillus bacteria for control of Candida infection, Hong Kong Medical Journal. 2016, 22 (Suppl 7): S34-36.
Tonetti M., Jepsen S., Jin L. and Otomo-Corgel J., Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action, Journal of Clinical Periodontology. 2017, 44: 456-462.
WANG Y., Liu H.N., ZHEN Z., Yiu K.H., Tse H.F., Pelekos G. and Jin L., Decreased CPC/EPC counts in type 2 diabetes patients with periodontitis, Journal of Dental Research. 2017, 96 (Spec Iss B): 153.
WANG Y., Liu H.N., Zhen Z., Yiu K.H., Pelekos G., Tse H.F. and Jin L., Periodontal treatment affects gene expression of EPCs in DM patients, Journal of Dental Research. 2017, 96 (Spec Iss A): 2195.
ZHAO D., Yiu K.H., ZHEN Z., Pelekos G. and Jin L., Deterioration of periodontal conditions reflects individual susceptibility to systemic comorbidities?, Journal of Dental Research. 2017, 96 (Spec B): 191.
ZHAO D., Yiu K.H., Zhen Z., Pelekos G. and Jin L., Periodontitis is linked to noncommunicable diseases among dental hospital attendees, Journal of Dental Research. 2017, 96 (Spec Iss A): 0963.
Zhou S.Y., Mahmood H., Cao C.F. and Jin L., Teeth under high occlusal force may reflect occlusal trauma-associated periodontal conditions in subjects with untreated chronic periodontitis, Chinese Journal of Dental Research. 2017, 20: 19-26.


Researcher : Lai SML

List of Research Outputs

CHAN C.K., Ho K.L., Lai S.M.L., Lam K.F. and Wong M.C.M., Tooth loss in patients undergoing supportive periodontal maintenance care, Journal of Dental Research. 2017, 96 (Spec Iss A): 1597.
Zee K.-.Y., Chan P.S., Ho J.C.S., Lai S.M.L., Corbet E.F. and Leung W.K., Adjunctive use of modified Yunu-Jian in the non-surgical treatment of male smokers with chronic periodontitis: a randomized double-blind, placebo-controlled clinical trial, Chinese Medicine. 2016, 11: 40.


Researcher : Leung WK

Project Title:79th General Session and Exhibition of the International Association for Dental Research Predominant Cultivable Subgingival Flora of Renal Transplant Recipients
Investigator(s):Leung WK
Department:Dental Faculty
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2001


Project Title:A randomized clinical trial using Rofecoxib as an adjunct to promote periodontal healing in non-surgical mechanical therapy on smokers
Investigator(s):Leung WK
Department:Dental Faculty
Source(s) of Funding:Other Funding Scheme
Start Date:12/2003


Project Title:The role of periodontal resident cell TLR4 signaling and HIF-1α biology in modulating autophagy in human chronic periodontitis
Investigator(s):Leung WK
Department:Dental Faculty-OralDiagnosis&Polyclinics
Source(s) of Funding:Small Project Funding
Start Date:05/2014


Project Title:Protective effect of oral lining cells against anaerobic periodontal infection: Does microbe associated molecular pattern recognition interact with hypoxic preconditioning?
Investigator(s):Leung WK, Fung ML, Tsao GSW
Department:Dental Faculty-OralDiagnosis&Polyclinics
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2014


Project Title:In vitro study of salivary pellicle formation on dental restorative material surfaces.
Investigator(s):Leung WK, Botelho MG
Department:Dental Faculty-OralDiagnosis&Polyclinics
Source(s) of Funding:Small Project Funding
Start Date:04/2015


Project Title:Genetic risks for chronic periodontitis: A genome-wide association study
Investigator(s):Leung WK, Song Y, Samartzis D, Cheah KSE, Cheung KMC, Sham PC, Chan D, Luk KDK
Department:Dental Faculty-OralDiagnosis&Polyclinics
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


Project Title:Analysis of microbial metagenome associated with periodontal disease
Investigator(s):Leung WK, Watt RM, Chan YK
Department:Dental Faculty-OralDiagnosis&Polyclinics
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2016


Project Title:Investigating bacterial adhesion to restorative material surfaces: Prelude to recurrent caries formation around filled tooth surfaces
Investigator(s):Leung WK, Botelho MG
Department:Dental Faculty - Periodontology
Source(s) of Funding:Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:07/2016
Completion Date:11/2016


List of Research Outputs

Goh V., Corbet E.F. and Leung W.K., Impact of dentine hypersensitivity on oral health-related quality of life in individuals receiving supportive periodontal care, Journal of Clinical Periodontology. 2016, 43: 595-602.
Goh V., Hackmack P.P., Corbet E.F. and Leung W.K., Moderate- to long-term periodontal outcomes of subjects failing to complete a course of periodontal therapy, Australian Dental Journal. 2017, 62: 152-160.
Goh V., Goo C.L. and Leung W.K., Prevention of peri-implantitis should start at treatment planning, In: Leon V. Berhardt, Advances in Medicine and Biology. New York, Nova Science Publishers, Inc. Hauppauge, 2017, 116: Chapter 9, pp. 129-199.
HUO Y., Chan Y.K., Lacap-Bugler D.C., Mo S., Woo P.C.Y., Leung W.K. and Watt R.M., Multilocus Sequence Analysis of Phylogroup 1 and 2 Oral Treponeme Strains, Applied and Environmental Microbiology. 2017, 83: e02499-16.
WANG X., CHEN Y. and Leung W.K., Role of the Hypoxia-Inducible Factor in Periodontal Inflammation, In: Jing Zheng, Chi Zhou, Hypoxia and Human Diseases. InTech, 2017, 285-302.
YU X., Chan Y.K., Zhuang L.F., Lai H.C., Lang N., Leung W.K. and Watt R.M., Oral microbiota in healthy versus diseased periodontal and peri-implant niches, J Dent Res 96 (Spec Iss A):2109), 2017.
Yeung W.K.A., Goto T.K. and Leung W.K., A bibliometric review of research trends in neuroimaging, Current Science. 2017, 112: 725-734.
Yeung W.K.A., Goto T.K. and Leung W.K., Basic taste processing recruits bilateral anteroventral and middle dorsal insulae: An activation likelihood estimation meta-analysis of fMRI studies, Brain and Behavior. 2017, 7: e00655.
Yeung W.K.A. and Leung W.K., Review of Docphin: An App for Mobile Access to Medical Journals, Journal of Digital Imaging. 2017, 30: 130-132.
Yeung W.K.A. and Leung W.K., Review of Radiology: App for Android by the Radiological Society of North America (RSNA), Journal of Digital Imaging. 2017, 30: 1-3.
Yeung W.K.A., Goto T.K. and Leung W.K., The Changing Landscape of Neuroscience Research, 2006–2015: A Bibliometric Study, Frontiers in Neuroscience. 2017, 11: 120.
You M., Chan Y.K., Lacap-Bugler D.C., Huo Y.B., Gao W., Leung W.K. and Watt R.M., Oral treponeme major surface protein: Sequence diversity and distributions within periodontal niches, Molecular Oral Microbiology. 2017, 32: 455-474.
Zee K.-.Y., Chan P.S., Ho J.C.S., Lai S.M.L., Corbet E.F. and Leung W.K., Adjunctive use of modified Yunu-Jian in the non-surgical treatment of male smokers with chronic periodontitis: a randomized double-blind, placebo-controlled clinical trial, Chinese Medicine. 2016, 11: 40.


Researcher : Liu HN

List of Research Outputs

WANG Y., Liu H.N., ZHEN Z., Yiu K.H., Tse H.F., Pelekos G. and Jin L., Decreased CPC/EPC counts in type 2 diabetes patients with periodontitis, Journal of Dental Research. 2017, 96 (Spec Iss B): 153.
WANG Y., Liu H.N., Zhen Z., Yiu K.H., Pelekos G., Tse H.F. and Jin L., Periodontal treatment affects gene expression of EPCs in DM patients, Journal of Dental Research. 2017, 96 (Spec Iss A): 2195.


Researcher : Luo W

List of Research Outputs

LI X., Luo W., Ng T.W., Leung P.C., Zhang C., Leung K.C.F. and Jin L., Mesoporous silica nanoparticle-encapsulated Scutellaria baicalensis as a promising immuno-inflammatory modulator for periodontal care, PgMelbourne2017: the 3rd International Conference on Porphyromonas gingivalis and Related Species in Oral and Systemic Diseases, May 14-16, 2017, Melbourne, Australia. 2017.


Researcher : Pang KY

List of Research Outputs

LI X., Pang K.Y., Ng T.W., Leung P.C., Zhang C., Leung K.C.F. and Jin L., Cellular Interactions and Formation of an Epithelial “Nanocoating-Like Barrier” with Mesoporous Silica Nanoparticles, Nanomaterials. 2016, 6: 192.


Researcher : Pelekos G

Project Title:Expression profile of Porphyromonas gingivalis/LPS-induced inflammatory biomarkers in human reconstituted kidney epithelial cells
Investigator(s):Pelekos G, Jin L
Department:Dental Faculty - Periodontology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2015


Project Title:Effect of adjunctive probiotic therapy on periodontal pocket microbiome: A randomized placebo controlled parallel arm study
Investigator(s):Pelekos G
Department:Dental Faculty - Periodontology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:02/2017


List of Research Outputs

Liu F., Pelekos G. and Jin L., The gingival biotype in a cohort of Chinese subjects with and without history of periodontal disease, Journal of Dental Research. 2017, 96 (Spec Iss A): 3480.
Nibali L., Kaiser F., Alagarswami R., Henderson B., Pelekos G. and Donos N., Differential circulating levels of HSP-27 in chronic and aggressive periodontitis, Journal of Dental Research. 2017, 96 (Spec Iss A): 1748.
WANG Y., Liu H.N., ZHEN Z., Yiu K.H., Tse H.F., Pelekos G. and Jin L., Decreased CPC/EPC counts in type 2 diabetes patients with periodontitis, Journal of Dental Research. 2017, 96 (Spec Iss B): 153.
WANG Y., Liu H.N., Zhen Z., Yiu K.H., Pelekos G., Tse H.F. and Jin L., Periodontal treatment affects gene expression of EPCs in DM patients, Journal of Dental Research. 2017, 96 (Spec Iss A): 2195.
ZHAO D., Yiu K.H., ZHEN Z., Pelekos G. and Jin L., Deterioration of periodontal conditions reflects individual susceptibility to systemic comorbidities?, Journal of Dental Research. 2017, 96 (Spec B): 191.
ZHAO D., Yiu K.H., Zhen Z., Pelekos G. and Jin L., Periodontitis is linked to noncommunicable diseases among dental hospital attendees, Journal of Dental Research. 2017, 96 (Spec Iss A): 0963.


Researcher : Tonetti M

List of Research Outputs

Cairo F., Cortellini P., Pilloni A., Nieri M., Cincinelli S., Amunni F., Pagavino G. and Tonetti M., Clinical efficacy of coronally advanced flap with or without connective tissue graft for the treatment of multiple adjacent gingival recessions in the aesthetic area: a randomized controlled clinical trial, Journal of Clinical Periodontology. 2016, 43: 849-856.
Cairo F., Pagliaro U., Buti J., Baccini M., Graziani F., Tonelli P., Pagavino G. and Tonetti M., Root coverage procedures improve patient aesthetics. A systematic review and Bayesian network meta-analysis, Journal of Clinical Periodontology. 2016, 43: 965-975.
Cortellini P., Buti J., Pini Prato G.L. and Tonetti M., Periodontal regeneration compared with access flap surgery in human intra-bony defects 20-year follow-up of a randomized clinical trial: tooth retention, periodontitis recurrence and costs, Journal of Clinical Periodontology. 2017, 44: 58-66.
Kilian M., Chapple I.L.C., Hannig M., Marsh P.D., Meuric V., Pedersen A.M.L., Tonetti M., Wade W.G. and Zaura E., The oral microbiome – an update for oral healthcare professionals, British Dental Journal. 2016, 221: 657-666.
Miron R.J., Sculean A., Cochran D.L., Froum S., Zucchelli G., Nemcovsky C., Donos N., Lyngstadaas S.P., Deschner J., Dard M., Stavropoulos A., Zhang Y., Trombelli L., Kasaj A., Shirakata Y., Cortellini P., Tonetti M., Rasperini G., Jepsen S. and Bosshardt D.D., Twenty years of enamel matrix derivative: the past, the present and the future, Journal of Clinical Periodontology. 2016, 43: 668-683.
Tonetti M., Bottenberg P., Conrads G., Eickholz P., Heasman P., Huysmans M.-.C., Lopez R., Madianos P., Muller F., Needleman I., Nyvad B., Preshaw P.M., Pretty I., Renvert S., Schwendicke F., Trombelli L., van der Putten G.-.J., Vanobbergen K., West N., Young A. and Paris S., Dental caries and periodontal diseases in the ageing population: call to action to protect and enhance oral health and well-being as an essential component of healthy ageing - Consensus report of group 4 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases, Journal of Clinical Periodontology. 2017, 44: S135-S144.
Tonetti M., Cortellini P., Graziani F., Cairo F., Lang N.P., Abundo R., Conforti G.P., Marquardt S., Rasperini G., Silvestri M., Wallkamm B. and Wetzel A., Immediate versus delayed implant placement after anterior single tooth extraction: the timing randomized controlled clinical trial , Journal of Clinical Periodontology. 2017, 44: 215-224.
Tonetti M., Jepsen S., Jin L. and Otomo-Corgel J., Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action, Journal of Clinical Periodontology. 2017, 44: 456-462.


Researcher : WANG X

List of Research Outputs

WANG X., CHEN Y. and Leung W.K., Role of the Hypoxia-Inducible Factor in Periodontal Inflammation, In: Jing Zheng, Chi Zhou, Hypoxia and Human Diseases. InTech, 2017, 285-302.


Researcher : ZHAO D

List of Research Outputs

ZHAO D., Yiu K.H., ZHEN Z., Pelekos G. and Jin L., Deterioration of periodontal conditions reflects individual susceptibility to systemic comorbidities?, Journal of Dental Research. 2017, 96 (Spec B): 191.
ZHAO D., Yiu K.H., Zhen Z., Pelekos G. and Jin L., Periodontitis is linked to noncommunicable diseases among dental hospital attendees, Journal of Dental Research. 2017, 96 (Spec Iss A): 0963.


-- End of Listing --