Clinical Trials Ctr

Research and Scholarship 2005

CLINICAL TRIALS CENTRE



Researcher : Cheung YB

List of Research Outputs

Cheung Y.B., Machin D., Karlberg J.P.E. and Khoo K.S., A Longitudinal study of pediatric body mass index values predicted health in middle age, Journal of Clinical Epidemilogy. 2004, 57: 1316-22.


Researcher : Fong DYT

List of Research Outputs

Chan G.C.F., Ng M.W., Lam W.W.T., Fong D.Y.T., Lau T.T.H., Wong K.Y. and Fielding R., Selective abortion for congenital disorders: Discordance in attitudes among professionals and laymen, Joint Annual Scientific Meeting 2004, The Hong Kong Paediatric Society, Hong Kong, 27 November 2004. 16.
Cheung B.M.Y., Lo L.F., Fong D.Y.T., Chan M.Y., Wong W.H.S., Lau C.P., Lam K.S.L., Wong V.C.N. and Karlberg J.P.E., Randomised Controlled Trial of Qigong in Hypertension, Cardiovasc Drugs Thera. 2004, 28 (suppl) 1: 28.
Cheung B.M.Y., Lo L.F., Fong D.Y.T., Chan M.Y., Wong W.H.S., Lau C.P., Lam K.S.L., Wong V.C.W. and Karlberg J.P.E., Randomised controlled trial of qigong in hypertension, J Hong Kong Coll Cardiol. 2004, 12: 34.
Cheung B.M.Y., Lo L.F., Fong D.Y.T., Chan M.Y., Wong S.H.T., Wong V.C.W., Lam K.S.L., Lau C.P. and Karlberg J.P.E., Randomised controlled trial of qigong in the treatment of mild essential hypertension, J Hum Hypertens. 2005, 19(9): 697-704.
Cheung S.T., Leung K.L., Ip Y.C., Chen X., Fong D.Y.T., Ng I.O.L., Fan S.T. and So S., Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 551-556.
Cheung S.T., Ho J.C.Y., Leung K.L., Chen X., Fong D.Y.T., So S. and Fan S.T., Transcript AA454543 is a novel prognostic marker for hepatocellular carcinoma after curative partial hepatectomy, Neoplasia. 2005, 7(2): 91-98.
Fong D.Y.T., False Positive Error in the Analysis of Paired Quality of Life Data, 11th Annual Conference of the International Society for Quality of Life Research, October 16-19, 2004. 13 (9): 1521.
Lam K.F., Fong D.Y.T. and Tang O.Y., Estimating the proportion of cured patients in a censored sample, Statistics in Medicine. 2005, 24: 1865-1879.
Mok M.Y., JacK D.L., Lau W.C.S., Fong D.Y.T., Turner M.W., Isenberg D.A. and Lydyard P.M., Antibodies to mannose binding lectin in patients with systemic lupus erythmatosus, Lupus. 2004, 13: 522-528.
Mok T.M.Y., Chan E.Y.T., Fong D.Y.T., Leung K.F.S., Wong W.S. and Lau W.C.S., Antiphospholipid Antibody Profiles and Their Clinical Associations in Chinese Patients with Systemic Lupus Erythematosus, The Journal of Rheumatology. 2005, 32 (4): 622-8.
Ni G., Lu W.W., Chiu P.K.Y. and Fong D.Y.T., Review article: Cemented or uncemented femoral component in primary total hip replacement? A review from a clinical and radiological perspective , Journal of Orthopaedic Surgery. 2005, 13(1): 96-105.


Researcher : Huang J

List of Research Outputs

Huang J., An Evidence-Based Approach to H. pylori Treatment Failures, Asia-Pacific Digestive Disease Week, Beijing, China, October 4, 2004.
Huang J., Chairman of Free paper session: Hepatology, Asia-Pacific Digestive Week 2004 in Beijing, Thursday, October 7th, 2004.
Huang J., Zheng G., Hunt R.H., Wong R.W.M., Lam S.K., Karlberg J.P.E. and Wong B.C.Y., Do patients with non-ulcer dyspepsia respond differently to Helicobacter pylorieradication treatments from those with peptic ulcer disease? A systemic review, World Journal of Gastroenterology. 2005, 11 (18): 2726-2732.
Huang J., Zheng G., Chan G.C.F., Karlberg J.P.E., Lam S.K. and Wong B.C.Y., Efficacy of Current Antiemetic Treatments for Preventing Delayed Chemotherapy-Induced Nausea and Vomiting: A Meta-Analysis of Randomized Controlled Trials, Clinical Research and Regulatory Affairs. 2004, 21 (3&4): 191-212.
Huang J., Efficacy of Current Antiemetic Treatments for Preventing Delayed Chemotherapy-Induced Nausea and Vomiting: a Meta-Analysis of Randomized Controlled Trials, Oral presentation at the 29th ESMO Congress, Vienna, Austria, Oct. 31 2004.
Huang J., Efficacy of Current Antiemetic Treatments for Preventing Delayed Chemotherapy-Induced Nausea and Vomiting: a Meta-Analysis of Randomized Controlled Trials, Supportive Care, 29th ESMO Congress, Vienna, Austria, October, 31, 2004.
Huang J., Evidence-Based Gastroenterology in the Management of Patients with GERD, "Training the Trainer" workshop, Seoul, Korea, July 7-9th, 2004 (organized by AstraZeneca). 2004.
Huang J., Evidence-Based Management of Patients with GERD, How much difference can Nexium make? AstraZeneca Asia-Pacific GI summit. Beijing, China, Oct 3rd, 2004.
Huang J., From opinion-based medicine to evidence-based medicine, Has the paradigm been shifted? Department of Gastroenterology, Union Hospital, Tongji Medical University, Wuhan, Hubei, China, Oct. 22, 2004.
Huang J., H. pylori, NSAID and PUD, 5th Western Pacific Helicobacter Congress, Kobe, Japan, November 17-19, 2004.
Huang J., Medical Statistics and Clinical Research Methodology, Asia-Pacific Digestive Disease Week, Beijing, China, October 4, 2004.
Huang J., Which proton pump inhibitor (ppi) is more effective for treating patients with erosive esophagitis (ee)? A meta-analysis of randomized comparative trials, The 4th Asia-Pacific Digestive Week, Beijing, China, Oct. 3-7, 2004.
Wang W.H., Huang J., Zheng G., Wong R.W.M., Lam S.K., Karlberg J.P.E., Xia H.H.X., Fass R. and Wong B.C.Y., Is Proton Pump Inhibitor Testing an Effective Approach to Diagnose Gastroesophageal Reflux Disease in Patients With Noncardiac Chest Pain?, Archives of Internal Medicine. 2005, 165: 1222-1228.
Wong R.W.M., Huang J., Xia H.H.X., Fung F.M.Y., Tong S.M., Cheung K.L., Ho Y.K., Lai K.C., Chan C.K., Chan O.O., Hui C.K., Lam S.K. and Wong B.C.Y., Low-dose rabeprazole, amoxicillin and metronidazole triple therapy for the treatment of Helicobacter pylori infection in Chinese patients, Journal of Gastroenterology and Hepatology. 2005, 20(6): 935-940.


Researcher : Karlberg JPE

Project Title:Long-term health consequences of insults in early life
Investigator(s):Karlberg JPE, Low LCK
Department:Paediatrics & Adolescent Medicine
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:11/1995
Abstract:
To understand the impact of early insults for health in adult-hood.


List of Research Outputs

Cheung B.M.Y., Lo L.F., Fong D.Y.T., Chan M.Y., Wong W.H.S., Lau C.P., Lam K.S.L., Wong V.C.N. and Karlberg J.P.E., Randomised Controlled Trial of Qigong in Hypertension, Cardiovasc Drugs Thera. 2004, 28 (suppl) 1: 28.
Cheung B.M.Y., Lo L.F., Fong D.Y.T., Chan M.Y., Wong W.H.S., Lau C.P., Lam K.S.L., Wong V.C.W. and Karlberg J.P.E., Randomised controlled trial of qigong in hypertension, J Hong Kong Coll Cardiol. 2004, 12: 34.
Cheung B.M.Y., Lo L.F., Fong D.Y.T., Chan M.Y., Wong S.H.T., Wong V.C.W., Lam K.S.L., Lau C.P. and Karlberg J.P.E., Randomised controlled trial of qigong in the treatment of mild essential hypertension, J Hum Hypertens. 2005, 19(9): 697-704.
Cheung Y.B., Machin D., Karlberg J.P.E. and Khoo K.S., A Longitudinal study of pediatric body mass index values predicted health in middle age, Journal of Clinical Epidemilogy. 2004, 57: 1316-22.
Huang J., Zheng G., Hunt R.H., Wong R.W.M., Lam S.K., Karlberg J.P.E. and Wong B.C.Y., Do patients with non-ulcer dyspepsia respond differently to Helicobacter pylorieradication treatments from those with peptic ulcer disease? A systemic review, World Journal of Gastroenterology. 2005, 11 (18): 2726-2732.
Huang J., Zheng G., Chan G.C.F., Karlberg J.P.E., Lam S.K. and Wong B.C.Y., Efficacy of Current Antiemetic Treatments for Preventing Delayed Chemotherapy-Induced Nausea and Vomiting: A Meta-Analysis of Randomized Controlled Trials, Clinical Research and Regulatory Affairs. 2004, 21 (3&4): 191-212.
Karlberg J.P.E., Health Regulatory Framework between Hong Kong & Mainland China - Opportunities from Alignment, "2005 Technology Drivers for Tomorrow" - Medical Diagnostics & Devices, Hong Kong, 15-16 March 2005. 2005.
Karlberg J.P.E., Preventing fraud and misconduct by GCP accreditation education, Good Clinical Practices & Clinical Trials Management, North Asian Summit, Shanghai, China, 24-25 February 2005. 2005.
Karlberg J.P.E., Problems in Collaboration between Physicians and the Industry in Clinical Trials, Conference on Cardiovascular Clinical Trials and Pharmacotherapy - Medical Directors' Forum, Hong Kong, 3 October 2004. 2004.
Karlberg J.P.E., The Asian Clinical Trial Arena - A Rapidly Changing Environment, Symposium on Cardiac Safety and the Asian Clinical Trial Arena, Singapore, 16-17 November 2004. 2004.
Karlberg J.P.E., hanterade vi misstänkta SARS-fall? Skrämdes vårdpersonal av medielarm? , Läkartidningen. 2004, 34 (101): 2586-7.
Wang W.H., Huang J., Zheng G., Wong R.W.M., Lam S.K., Karlberg J.P.E., Xia H.H.X., Fass R. and Wong B.C.Y., Is Proton Pump Inhibitor Testing an Effective Approach to Diagnose Gastroesophageal Reflux Disease in Patients With Noncardiac Chest Pain?, Archives of Internal Medicine. 2005, 165: 1222-1228.
Wong B.C.Y., Fong D.Y.T. and Karlberg J.P.E., Translation of the Rome II Modular Questionnaire, AstraZeneca AB. 2005.
Xu X., Guo Z.P., Wang W.P. and Karlberg J.P.E., Longitudinal study on the age at childhood onset in children from Shanghai and its effects on child growth, Chinese Journal of Pediatrics. 2004, 42 (12): 902-907.


Researcher : Ma ESK

Project Title:Genetic modifiers of [beta]-thalassaemia phenotype in the Chinese
Investigator(s):Ma ESK, Tan-Un KC
Department:Pathology
Source(s) of Funding:Competitive Earmarked Research Grants (CERG)
Start Date:12/2002
Completion Date:11/2004
Abstract:
The project is to investigate genetic modifiers of [beta]-thalassaemia phenotype in Chinese patients at candidate gene loci responsible for [gamma]-globin chain production, iron metabolism, bilirubin metabolism and collagen synthesis. The information gathered is applicable not only to genetic counselling and prenatal diagnosis, but will also provide prognostic indicators on which management decisions can be based.


Project Title:Quantification of mutant transcripts in mild and silent [beta]-thalassaemia alleles of the Chinese by real time polymerase chain reaction
Investigator(s):Ma ESK
Department:Pathology
Source(s) of Funding:Small Project Funding
Start Date:11/2003
Completion Date:10/2004
Abstract:
To determine the level of mutant transcripts in these mild and silent [beta]-thalassaemia alleles by real time polymerase chain reaction.




Researcher : Machin D

List of Research Outputs

Cheung Y.B., Machin D., Karlberg J.P.E. and Khoo K.S., A Longitudinal study of pediatric body mass index values predicted health in middle age, Journal of Clinical Epidemilogy. 2004, 57: 1316-22.


Researcher : Yau KC

List of Research Outputs

Yau K.C., Risk Assessments in Clinical Research - A Study Site Perspective, Ethics, Legal Issues & Risk Management in Clinical Research, Singapore, 19-20 January 2005.


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