Dept of Microbiology

DEPT OF MICROBIOLOGY

Researcher : Bahl J

List of Research Outputs

Bahl J., Leung C.Y.H., Smith G.J., Ellis T., Dyrting K.C., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of viruses isolated from wild birds in Hong Kong, NIAID Centers of Excellence for influenza Research and Surveillance, 3rd Annual CEIRS Network Meeting . 2009.

Bahl J., Dhanasekaran V., Holmes E.C., Smith G.J. and Guan Y., Gene flow and competitive exclusion in Avian influenza A virus, Epidemics1 – First International conference on Infectious Disease Dynamics. 2008.

Bahl J., Dhanasekaran V., Holmes E.C., Smith G.J. and Guan Y., Gene flow and competitive exclusion of avian influenza A virus. , Virology. 2009, 390: 289-297.

Dhanasekaran V., Bahl J., Riley S., Duan L., Zhang J., Chen H., Peiris J.S.M., Smith G.J. and Guan Y., Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses, PLoS Pathogens. 2008, 26: e1000161.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Ducatez M., Bahl J., Stigger E., Griffin Y., Webb A., Guan Y., Smith G.J. and Webby R., Generation of ancestral H5N1 influenza viruses as vaccine and diagnostic reagents, The Third International Conference on Influenza Vaccines for the World, Palais des Festivals et des Congres, Cannes Cedex, France. 2009.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Smith G.J., Dhanasekaran V., Bahl J., Lycett S.J., Worobey M., Pybus O.G., Ma S.K., Cheung C.L., Raghwani J., Bhatt S., Peiris J.S.M., Guan Y. and Rambaut A., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Nature. UK, Nature, 2009, 459: 1122-1125.

Researcher : Cai J

List of Research Outputs

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Researcher : Chan CM

List of Research Outputs

Chan C.M., Tse H., Wong S.S.Y., Woo P.C.Y., Lau S.K.P., Chen L., Zheng B., Huang J. and Yuen K.Y., Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. , J Clin Virol. 2009, 45(1): 54-60.

Chan C.M., Lau S.K.P., Woo P.C.Y., Tse H., Zheng B., Chen L., Huang J. and Yuen K.Y., Identification of Major Histocompatibility Antigen Class I C as an attachment coreceptor that facilitates Coronavirus HKU1 Spike-mediated infection, J Viral . 2009, 16(1): 45-52.

Chan C.M., Woo P.C.Y., Lau S.K.P., Tse H., Chen H., Li F., Zheng B., Chen L., Huang J. and Yuen K.Y., Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection, Exp Biol Med (Maywood). 2008, 33 (12): 1527-1536.

Siu Y.L., Teoh K.T., Lo J.C.Y., Chan C.M., Kien F.S., Escriou N., Tsao G.S.W., Nicholls J.M., Altmeyer R.M., Peiris J.S.M., Bruzzone R. and Nal-Rogier B.T.M., The M, E and N structural proteins of the SARS coronavirus are required for efficient assembly, trafficking and release of virus-like particles., Journal of Virology. 2008.

Siu Y.L., Teoh K.T., Lo J.C.Y., Chan C.M., Kien F.S., Escriou N., Tsao G.S.W., Nicholls J.M., Altmeyer R.M., Peiris J.S.M., Bruzzone R. and Nal-Rogier B.T.M., The M, E, And N Structural Proteins Of The Severe Acute Respiratory Syndrome Coronavirus Are Required For Efficient Assembly, Trafficking, And Release Of Virus-like Particles., Journal of Virology. 2008, 82(22): 11318-30.

Researcher : Chan CM

List of Research Outputs

Researcher : Chan CS

List of Research Outputs

Zeng Y., Chan K.C.W., Chan C.S., Ng F., Wong K.H. and Zheng B., Detection of HIV specific cytotoxic T lymphocytes viral delivery system, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., He Y., Jiang S., Wu C., Jin D., Zhou Y. and Yuen K.Y., SARS-CoV S Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection. , Vaccine 2nd Congress. Boston, MA, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Researcher : Chan JFW

List of Research Outputs

Cheng V.C.C., Yam W.C., Chan J.F.W., To K.K.W., Ho P.L. and Yuen K.Y., Clostridium difficile ribotype 027 arrives in Hong Kong., International Journal of Antimicrobial Agents. 2009, 54(5): 492-493.

Cheng V.C.C., Chan J.F.W., To K.K.W., Tai J.W.M. and Ho P.L., Detection of community-associated MRSA as a result of the unmasking effect of antibiotic treatment., Journal of Hospital Infection. 2009, 72: 273-4.

Researcher : Chan JSY

List of Research Outputs

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Researcher : Chan KCW

List of Research Outputs

Chen J.H.K., Wong K.H., Li P., Chan K.C.W., Lee M.P., Lam H.Y., Cheng V.C.C., Yuen K.Y. and Yam W.C., Molecular Epidemiological Study of HIV-1 CRF01_AE Transmission in Hong Kong , In: David D. Ho, MD, Paul A. Volberding, MD, William A. Blattner, MD, Journal of Acquired Immune Deficiency Syndromes. Wolters Kluwer, Lippincott Williams & Wilkins, 2009, 51: 530-535.

Zeng Y., Chan K.C.W., Chan C.S., Ng F., Wong K.H. and Zheng B., Detection of HIV specific cytotoxic T lymphocytes viral delivery system, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zheng B., Zhao X., Lee S.S., Wong K.H., Chan K.C.W., Ng F., Yam W.C. and Yuen K.Y., Study of Polymorphisms in HIV-1 Co-receptors and Their Ligands in Chinese Population and Their Effects on HIV-1 Infection, XVII International AIDS Conference. Mexico City, Mexico, 2008.

Researcher : Chan KH

List of Research Outputs

Cheng K.Y., Cowling B.J., Fang J., Chan K.H., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Effects of oseltamivir on severity and duration of symptoms, viral shedding, and infectivity of influenza (abstract), Hong Kong College of Community Medicine 2008 Annual Scientific Meeting, 27 September 2008, Hong Kong. Hong Kong, Hong Kong College of Community Medicine, 2008, Poster 23.

Chiu S.S.S., Chan K.H., Tu W., Lau Y.L. and Peiris J.S.M., Immunogenicity and safety of intradermal versus intramuscular route of influenza immunization in infants less than 6 months of age: a randomized controlled trial, Vaccine. 2009, doi:10.1016: J.vaccine.2009.05.066.

Cowling B.J., Leung G.M., Peiris J.S.M., Chan K.H., Yung R.W.H. and Seto W.H., A controlled trial of masks and hand hygiene for reducting influenza transmission, The University of Hong Kong (abstract), CDC Nonpharmaceutical Interventions for Pandemic Influenza PI Meeting, 4-6 March 2009, Atlanta. Atlanta, Centres for Disease Control and Prevention, 2009, 19-20.

Cowling B.J., Fung R.O.P., Fang J., Cheng K.Y., Lam C.L.K., Chan K.H., Seto W.H., Yung R., Chu D.W.S., Lee P., Chiu M.C., Lee H.C., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., A randomized trial of face masks and hand hygiene to prevent influenza transmission in households (abstract) (poster presentation), Third European Influenza Conference, 14-17 September 2008, Vilamoura, Portugal. Vilamoura, Portugal, European Scientific Working group on Influenza, 2008, 116.

Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Effects of antiviral son severity and duration of symptoms, viral shedding, and household transmission of influenza (abstract) (poster presentation), Third European Influenza Conference, 14-17 September 2008, Vilamoura, Portugal. Vilamoura, Portugal, European Scientific Working group on Influenza, 2008, 162.

Cowling B.J., Lau E.H.Y., Lam C.L.H., Cheng K.Y., Kovar J., Chan K.H., Peiris J.S.M. and Leung G.M., Effects of school closures, 2008 winter influenza season, Hong Kong, Emerging Infectious Diseases. 2008, 14(10): 1660-1662.

Cowling B.J., Chan K.H., Fang J., Cheng K.Y., Fung R.O.P., Lim Wai W.S., Sin J.W.F., Seto W.H., Yung R.W.H., Chu D.W.S., Chiu B.C.F., Lee P.W.Y., Chiu M.C., Lee H.C., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Findings of a cluster randomized controlled trial of face masks and hand hygiene to prevent influenza transmission in households (abstract and oral presentation), XI International Symposium on Respiratory Viral Infections, 19-22 February 2009, Bangkok, Thailand. Bangkok, Thailand, The Macrae Group LLC, 2009, I-2.

Fabian P., McDevitt J.J., DeHaan W.H., Fung R.O.P., Cowling B.J., Chan K.H., Leung G.M. and Milton D.K., Influenza virus in human exhaled breath: an observational study, PLoS One. 2008, 3(7): e2691.

Ho P.L., Wong M.P., Lai E.L.Y., Chan K.H. and Chiu S.S.S., DNA typing of cytological samples for retrospective identification of an early case of Panton-Valentine leucocidin-positive, community-associated methicillin-resistant Staphylococcus aureus pneumonia, J Clin Microbiol. 2008, 46: 2457-2458.

Lau L.H.L., Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., The relation between viral shedding and clinical course in natural influenza infections (abstract and poster presentation), XI International Symposium on Respiratory Viral Infections, 19-22 February 2009, Bangkok, Thailand. Bangkok, Thailand, The Macrae Group LLC, 2009, P-9.

Lau L.H.L., Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Peiris J.S.M. and Leung G.M., The time lines of viral shedding and clinical course in influenza infections (abstract), Hong Kong College of Community Medicine Annual Scientific Meeting, 14 June 2009, Hong Kong. Hong Kong, Hong Kong College of Community Medicine, 2009, Poster 26.

Lau S.K.P., Li K.S.M., Chau K.Y., So L.Y., Lee R.A., Lau Y.L., Chan K.H., Lim W.W.L., Woo P.C.Y. and Yuen K.Y., Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A, Journal of Clinical Microbiology. 2009, 47(5): 1549-1552.

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Ng S., Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Effects of oseltamivir treatment on duration of symptoms and viral shedding, and household transmission of influenza virus (abstract and poster presentation), XI International Symposium on Respiratory Viral Infections, 19-22 February 2009, Bangkok, Thailand. Bangkok, Thailand, The Macrae Group LLC, 2009, P-10.

Ng S., Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Peiris J.S.M. and Leung G.M., Treatment of influenza infection with oseltamivir to reduce duration of clinical illness and viral shedding, and household transmission (abstract), Hong Kong College of Community Medicine Annual Scientific Meeting, 14 June 2009, Hong Kong. Hong Kong, Hong Kong College of Community Medicine, 2009, Poster 24.

Poon L.L.M., Chan K.H., Leung C.S.W., Smith G.J., Guan Y., Yuen K.Y. and Peiris J.S.M., Molecular Detection of a Novel Human Influenza (H1N1) of Pandemic Potential by Conventional and Real-Time Quantitative RT-PCR Assays, Clinical Chemistry. 2009, 55: 1555-1558.

Wang W., Ren P., Mardi S., Mardi S., Hou L., Tsai C., Chan K.H., Cheng P., Sheng J., Buchy P., Sun B., Toyoda T., Lim W.W.L., Peiris J.S.M., Zhou P. and Deubel V., Design of multiplexed detection assays for identification of avian influenza a virus subtypes pathogenic to humans by SmartCycler real-time reverse transcription-PCR, Journal of Clinical Microbiology. 2008, 47(1): 86-92.

Xu X., Chan K.H. and Chiang A.K.S., Development of polychromatic flow cytometry assay to study polyfunctional Epstein-Barr Virus (EBV)-specific CD8+ cytotoxic T-lymphocyte responses, The 13^th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases, Guangzhou, PR China, 7-10 November 2008. 230.

Researcher : Chan KM

List of Research Outputs

Woo P.C.Y., Teng L.L., Tsang K.L., Tse H., Tsang V.Y.M., Chan K.M., Lee E.K.Y., Chan J.K.H., Tam D.M.W., Chung L.M.W., Lau S.K.P. and Yuen K.Y., Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea, BMC Microbiology. 2009, 9: 21.

Researcher : Chan MCW

List of Research Outputs

Li O.T.W., Chan M.C.W., Leung C.S.W., Chan W.Y., Guan Y., Nicholls J.M. and Poon L.L.M., Full factorial analysis of Mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation., In: Li OT, Chan MC, Leung CS, Chan RW, Guan Y, Nicholls JM, Poon LL., PLoS ONE. 2009, 21;4(5): e5658.

Nicholls J.M., Chan M.C.W., Chan W.Y., Cheung C.Y., Kwong D.L.W., Wong M.P., Poon L.L.M., Tsao G.S.W. and Guan Y., 2008 Research Output Prize/Faculty Outstanding Research Output Award, The University of Hong Kong. 2008.

Nicholls J.M., Chan M.C.W., Chan W.Y., Peiris J.S.M., Malakhov M., Li H., Huang Y., Zaltash S., Hawley S., Haslam S., Karamanska R. and Fang F., The use of sialidase treatment in influenza virus infection , XI International Symposium on Respiratory Viral Infections. 2009.

Researcher : Chan YO

List of Research Outputs

Law H.K.W., Cheung C.Y., Sia S.F., Chan Y.O., Peiris J.S.M. and Lau Y.L., Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells, BMC Immunology. 2009, 10: 35.

Researcher : Chen D

List of Research Outputs

Zeng Y., Zhou J., Chen D., Poon K.M., Ng F., Yuen K.Y. and Zheng B., A SNP in IFNGR1 promoter is correlated to the susceptibility to chronic HBV infection in Chinese population, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zhou J., Chen D., Poon K.M., Zeng Y., Ng F., Lu L., Huang J., Yuen K.Y. and Zheng B., A comprehensive study of interferon-γ receptor 1 gene polymorphisms and susceptibility to chronic hepatitis B virus infection. , Immunogenetics. 2009, 61(6): 423-430.

Zhou J., Smith D.K., Lu L., Poon K.M., Ng F., Chen D., Huang J., Yuen K.Y. and Zheng B., A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection, J Viral Hepat. 2009, 16(1): 45-52.

Researcher : Chen H

List of Research Outputs

Chan C.M., Woo P.C.Y., Lau S.K.P., Tse H., Chen H., Li F., Zheng B., Chen L., Huang J. and Yuen K.Y., Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection, Exp Biol Med (Maywood). 2008, 33 (12): 1527-1536.

Chen H., EBV modulates STAT signalling in Nasopharyngeal Carcinoma, AACR, Session - Infection and Cancer: Biology, therapeutics and Prevention, December, Hong Kong. 2008.

Chen H., Identification and characterization of host factors interacting with influenza virus, The fifth APSMI Annual Meeting, June 5-7, Shantou University, China. 2009.

Chen H., Molecular basis of influenza virus antigenic variations: antigenic profiling of avian H5N1 virus with monoclonal antibodies, 3rd Annual CEIRS Network Meeting, June 22-25, University of Minnesota, Minneapolis, USA. 2009.

Chen Y., Qin K., Wu W.L., Li G., Zhang J., Du H., Ng M.H., Shih W.K., Peiris J.S.M., Guan Y., Chen H. and Xia N., Broad Cross Protection Against H5N1 Avian Influenza Infection by Means of Monoclonal Antibodies that Map to conserved viral Epitopes, The Journal of Infectious Diseases. 2009, 199: 49-58.

Chen Y., Xu F., Fan X., Luo H., Ge S., Zheng Q., Xia N., Chen H., Guan Y. and Zhang J., Evaluation of a rapid test for detection of H5N1 avian influenza virus, Journal of Virological Methods. 2008, 154: 213-215.

Dhanasekaran V., Bahl J., Riley S., Duan L., Zhang J., Chen H., Peiris J.S.M., Smith G.J. and Guan Y., Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses, PLoS Pathogens. 2008, 26: e1000161.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Liu N., Song W., Lee K.C., Wang P., Chen H. and Cai Z., Identification of amino acid substitutions in avian influenza virus (H5N1) matrix protein 1 by using nanoelectrospray MS and MS/MS, Journal of the American Society for Mass Spectrometry. 2009, 20: 312-320.

Liu N., Lee K.C., Song W., Wang P., Cai Z. and Chen H., Identification of amino acid substitutions in mutated peptides of nucleoprotein from avian influenza virus, Talanta. 2009, 78: 1492-1496.

Luo W., Chen Y., Wang M., Chen Y., Zheng Z., Song H., Chen H., Guan Y., Ng M.H., Zhang J. and Xia N., Peptide mimics of a conserved H5N1 avian influenza virus neutralization site, Biochem. J.. 2009, 419: 133-139.

Owoade A.A., Ducatez M.F., Hubschen J.M., Sausy A., Chen H., Guan Y. and Muller C.P., Avian metapneumovirus subtype A in China and subtypes A and B in Nigeria, Avian Dis.. 2008, 52: 502-6.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Tsao G.S.W., Tsang C.M., Zhang G., Hau P.M., Man C.W.Y., Yip Y.L., Lee L.S., Seto E., Takada K., Cao Y., Chen H., Lo K.W., Jin D. and Kwong D.L.W., Establishment of stable infection of Epstein-Barr Virus in premalignant nasopharyngeal epithelial cells, Proceedings of EBV Symposium. 2008.

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Zhang Z., Zhang J., Huang K., Li K.S., Yuen K.Y., Guan Y., Chen H. and Ng W.F., Systemic infection of avian influenza A virus H5N1 subtype in human, Human Pathology. 2009, 40: 735-739.

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

Researcher : Chen JHK

List of Research Outputs

Chen J.H.K., Wong K.H., Li P., Chan K.C.W., Lee M.P., Lam H.Y., Cheng V.C.C., Yuen K.Y. and Yam W.C., Molecular Epidemiological Study of HIV-1 CRF01_AE Transmission in Hong Kong , In: David D. Ho, MD, Paul A. Volberding, MD, William A. Blattner, MD, Journal of Acquired Immune Deficiency Syndromes. Wolters Kluwer, Lippincott Williams & Wilkins, 2009, 51: 530-535.

Lee S.S., Tam D.K., Tan Y., Mak W.L., Wong K.H., Chen J.H.K. and Yam W.C., An exploratory study on the social and genotypic clustering of HIV infection in men having sex with men, In: JA Levy, AIDS. Lippincott Williams & Wilkins, 2009, 23: 1755-1764.

Researcher : Cheng VCC

List of Research Outputs

Chang K.C., Leung C.C., Yew W.W., Lam F.M., Ho P.L., Chau C.H., Cheng V.C.C. and Yuen K.Y., Analyses of fluoroquinolones and Clostridium difficile-associated diarrhoea in tuberculosis patients., The international journal of tuberculosis and lung disease. 2009, 13(3): 341-346.

Chen J.H.K., Wong K.H., Li P., Chan K.C.W., Lee M.P., Lam H.Y., Cheng V.C.C., Yuen K.Y. and Yam W.C., Molecular Epidemiological Study of HIV-1 CRF01_AE Transmission in Hong Kong , In: David D. Ho, MD, Paul A. Volberding, MD, William A. Blattner, MD, Journal of Acquired Immune Deficiency Syndromes. Wolters Kluwer, Lippincott Williams & Wilkins, 2009, 51: 530-535.

Cheng V.C.C., Yam W.C., Chan J.F.W., To K.K.W., Ho P.L. and Yuen K.Y., Clostridium difficile ribotype 027 arrives in Hong Kong., International Journal of Antimicrobial Agents. 2009, 54(5): 492-493.

Cheng V.C.C., Chan J.F.W., To K.K.W., Tai J.W.M. and Ho P.L., Detection of community-associated MRSA as a result of the unmasking effect of antibiotic treatment., Journal of Hospital Infection. 2009, 72: 273-4.

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

Ho P.L., Cheng V.C.C. and Chow K.H., Decreasing prevalence of levofloxacin-resistant Streptococcus pneumoniae in Hong Kong, 2001 to 2007., Journal of Antimicrobial Chemotherapy. 2009, 63: 836-8.

Wong S.Y.A., Cheng V.C.C., Yuen K.Y., Kwong Y.L. and Leung A.Y.H., High frequency of polyoma BK virus shedding in the gastrointestinal tract after hematopoietic stem cell transplantation: a prospective and quantitative analysis, Bone Marrow Transplantation. Epub, 2008, 43: 43–47.

Researcher : Cheung CL

List of Research Outputs

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Smith G.J., Dhanasekaran V., Bahl J., Lycett S.J., Worobey M., Pybus O.G., Ma S.K., Cheung C.L., Raghwani J., Bhatt S., Peiris J.S.M., Guan Y. and Rambaut A., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Nature. UK, Nature, 2009, 459: 1122-1125.

Researcher : Cheung CY

List of Research Outputs

Cheung C.Y., Lee M.Y. and Peiris J.S.M., Induction of pro-inflammatory mediators by H5N1 infection of primary human lung microvascular endothelial cells, CYTOKINE. 2008, 43(3): 259.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y., Poon L.L.M., Guan Y., Ip N.Y.Y., Lau A.S.Y. and Peiris J.S.M., Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK, The Journal of Immunology. 2009, 182: 1088-1098.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y. and Peiris J.S.M., Signaling Pathways Associated with H5N1-induced Cytokines and Chemokines, Gordon Research Conferences. 2009.

Hui P.Y., Lee M.Y., Cheung C.Y. and Peiris J.S.M., The role of interferon regulatory factor 3 and p38 in influenza a virus induced pro-inflammatory cytokines, CYTOKINE. 2008, 43(3): 259.

Law H.K.W., Cheung C.Y., Sia S.F., Chan Y.O., Peiris J.S.M. and Lau Y.L., Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells, BMC Immunology. 2009, 10: 35.

Lee M.Y., Cheung C.Y., Nicholls J.M. and Peiris J.S.M., Hyper-induction of COX-2-medicated proinflammatory cascade: A mechanism for the pathogenesis of avian influenza H5N1 infection , CYTOKINE. 2008, 43(3): 259.

Lee M.Y., Cheung C.Y., Nicholls J.M., Hui P.Y., Leung C.Y.H., Uiprasertkul M., Tipoe G.L., Lau Y.L., Poon L.L.M., Ip N.Y., Guan Y. and Peiris J.S.M., Hyperinduction of Cyclooxygenase-2-Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection, The Journal of Infectious Diseases. 2008, 198(4): 525-35.

Nicholls J.M., Chan M.C.W., Chan W.Y., Cheung C.Y., Kwong D.L.W., Wong M.P., Poon L.L.M., Tsao G.S.W. and Guan Y., 2008 Research Output Prize/Faculty Outstanding Research Output Award, The University of Hong Kong. 2008.

Researcher : Chow KH

List of Research Outputs

Ho P.L., Yip K.S., Chow K.H., Lo J.Y., Que T.L., Yuen K.Y. and Yuen K.Y., Antimicrobial resistance among uropathogens that cause acute uncomplicated cystitis in women in Hong Kong: a prospective multicenter study in 2006 to 2008., Diagnostic Microbiology and Infectious Disease. 2009.

Ho P.L., Wong R.C., Chow K.H., Yip K., Wong S.S.Y. and Que T.L., CTX-M type beta-lactamases among fecal Escherichia coli and Klebsiella pneumoniae isolates in non-hospitalized children and adults., Journal of Microbiology, Immunology and Infection. 2008, 41: 428-32.

Ho P.L., Chow K.H., Lo P.Y., Lee K.F. and Lai E.L.Y., Changes in the epidemiology of methicillin-resistant Staphylococcus aureus associated with spread of the ST45 lineage in Hong Kong., Diagnostic Microbiology and Infectious Disease. 2009, 64: 131-7.

Ho P.L., Cheng V.C.C. and Chow K.H., Decreasing prevalence of levofloxacin-resistant Streptococcus pneumoniae in Hong Kong, 2001 to 2007., Journal of Antimicrobial Chemotherapy. 2009, 63: 836-8.

Researcher : Chu KW

List of Research Outputs

Chu K.W., Poon L.L.M., Guan Y. and Peiris J.S.M., Novel astroviruses in insectivorous bats. , Journal of Virology. 2008, 82: 9107-9114.

Researcher : Curreem OTS

List of Research Outputs

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Researcher : Dhanasekaran V

List of Research Outputs

Bahl J., Dhanasekaran V., Holmes E.C., Smith G.J. and Guan Y., Gene flow and competitive exclusion in Avian influenza A virus, Epidemics1 – First International conference on Infectious Disease Dynamics. 2008.

Bahl J., Dhanasekaran V., Holmes E.C., Smith G.J. and Guan Y., Gene flow and competitive exclusion of avian influenza A virus. , Virology. 2009, 390: 289-297.

Dhanasekaran V., Bahl J., Riley S., Duan L., Zhang J., Chen H., Peiris J.S.M., Smith G.J. and Guan Y., Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses, PLoS Pathogens. 2008, 26: e1000161.

Donis R., Smith G.J., Brown I.H., Capua I., Cattoli G., Chen H., Cox N., Davis C.T., Fouchier R.A.M., Garten R., Guan Y., Hay A., Kawaoka Y., Mackenzie J., McCauley J.S.M., Mumford E., Olsen C., Perdue M.L., Russell C.A., Smith C., Smith D., Shu Y., Tashiro M., Dhanasekaran V. and Webster R.G., Continuing progress towards a unified nomenclature for the highly pathogenic H5N1 avian influenza viruses: Divergence of clade 2·2 viruses, Influenza and Other Respiratory Viruses. 2009, 3: 59-62.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Smith G.J., Dhanasekaran V., Bahl J., Lycett S.J., Worobey M., Pybus O.G., Ma S.K., Cheung C.L., Raghwani J., Bhatt S., Peiris J.S.M., Guan Y. and Rambaut A., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Nature. UK, Nature, 2009, 459: 1122-1125.

Thongkantha S., Jeewon R., Dhanasekaran V., Lumyong S., McKenzie E.H.C. and Hyde K.D., Molecular phylogeny of Magnaporthaceae (Sordariomycetes) with a new species Ophioceras chiandaoensis from Dracaena loureiri in Thailand, Fungal Diversity. 2009, 34: 155-171.

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

Researcher : Du L

List of Research Outputs

Du L., He Y., Zhou Y., Liu S., Zheng B. and Jiang S., The spike protein of SARS-CoV — a target for vaccine and therapeutic development. , Nat Rev Micro. 2009, 7(3):: 226-236.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., He Y., Jiang S., Wu C., Jin D., Zhou Y. and Yuen K.Y., SARS-CoV S Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection. , Vaccine 2nd Congress. Boston, MA, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Researcher : Duan L

List of Research Outputs

Dhanasekaran V., Bahl J., Riley S., Duan L., Zhang J., Chen H., Peiris J.S.M., Smith G.J. and Guan Y., Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses, PLoS Pathogens. 2008, 26: e1000161.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Researcher : Fan X

List of Research Outputs

Chen Y., Xu F., Fan X., Luo H., Ge S., Zheng Q., Xia N., Chen H., Guan Y. and Zhang J., Evaluation of a rapid test for detection of H5N1 avian influenza virus, Journal of Virological Methods. 2008, 154: 213-215.

Researcher : Fan YY

List of Research Outputs

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Researcher : Fu CT-Y

List of Research Outputs

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Researcher : Guan Y

List of Research Outputs

Bahl J., Leung C.Y.H., Smith G.J., Ellis T., Dyrting K.C., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of viruses isolated from wild birds in Hong Kong, NIAID Centers of Excellence for influenza Research and Surveillance, 3rd Annual CEIRS Network Meeting . 2009.

Bahl J., Dhanasekaran V., Holmes E.C., Smith G.J. and Guan Y., Gene flow and competitive exclusion in Avian influenza A virus, Epidemics1 – First International conference on Infectious Disease Dynamics. 2008.

Bahl J., Dhanasekaran V., Holmes E.C., Smith G.J. and Guan Y., Gene flow and competitive exclusion of avian influenza A virus. , Virology. 2009, 390: 289-297.

Carrington C.V.F., Foster J.E., Zhu H., Zhang J., Smith G.J., Thompson N., Auguste A.J., Ramkissoon V., Adesiyun A.A. and Guan Y., Detection and phylogenetic analysis of group 1 coronaviruses in South American bats., Emerg Infect Dis.. 2008, 14: 1890-1893.

Chen Y., Qin K., Wu W.L., Li G., Zhang J., Du H., Ng M.H., Shih W.K., Peiris J.S.M., Guan Y., Chen H. and Xia N., Broad Cross Protection Against H5N1 Avian Influenza Infection by Means of Monoclonal Antibodies that Map to conserved viral Epitopes, The Journal of Infectious Diseases. 2009, 199: 49-58.

Chen Y., Xu F., Fan X., Luo H., Ge S., Zheng Q., Xia N., Chen H., Guan Y. and Zhang J., Evaluation of a rapid test for detection of H5N1 avian influenza virus, Journal of Virological Methods. 2008, 154: 213-215.

Chu K.W., Poon L.L.M., Guan Y. and Peiris J.S.M., Novel astroviruses in insectivorous bats. , Journal of Virology. 2008, 82: 9107-9114.

Dhanasekaran V., Bahl J., Riley S., Duan L., Zhang J., Chen H., Peiris J.S.M., Smith G.J. and Guan Y., Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses, PLoS Pathogens. 2008, 26: e1000161.

Donis R., Smith G.J., Brown I.H., Capua I., Cattoli G., Chen H., Cox N., Davis C.T., Fouchier R.A.M., Garten R., Guan Y., Hay A., Kawaoka Y., Mackenzie J., McCauley J.S.M., Mumford E., Olsen C., Perdue M.L., Russell C.A., Smith C., Smith D., Shu Y., Tashiro M., Dhanasekaran V. and Webster R.G., Continuing progress towards a unified nomenclature for the highly pathogenic H5N1 avian influenza viruses: Divergence of clade 2·2 viruses, Influenza and Other Respiratory Viruses. 2009, 3: 59-62.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Ducatez M., Bahl J., Stigger E., Griffin Y., Webb A., Guan Y., Smith G.J. and Webby R., Generation of ancestral H5N1 influenza viruses as vaccine and diagnostic reagents, The Third International Conference on Influenza Vaccines for the World, Palais des Festivals et des Congres, Cannes Cedex, France. 2009.

Guan Y., Continuing endemic and evolution of H5N1 influenza virus in southern China: persistent pandemic threat, The Annual CEIRS Meeting held in Minneapolis, Minnesota (University of Minnesota) from 22 to 25 June. 2009.

Guan Y., Ecology and evolution of avian influenza A (H5N1) virus, 8th Asia Pacific Congress of Medical Virology in Hong Kong Convention and Exhibition Centre from 25 to 28 February. 2009.

Guan Y., Emergence and Establishment of H5N1 Influenza Virus in Eurasia and Africa: Implication for Pandemic Control., Asia Business Forum (ABF), Hong Kong. 2008.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y., Poon L.L.M., Guan Y., Ip N.Y.Y., Lau A.S.Y. and Peiris J.S.M., Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK, The Journal of Immunology. 2009, 182: 1088-1098.

Kung H., He M.L., Zheng B., Guan Y., Lin M.C. and Peng Y., Inhibition of SARS-Associated Coronavirus (SCoV) Infection and Replication by RNA Interference, U.S. Patent No. 7,429,656. 2008.

Lee M.Y., Cheung C.Y., Nicholls J.M., Hui P.Y., Leung C.Y.H., Uiprasertkul M., Tipoe G.L., Lau Y.L., Poon L.L.M., Ip N.Y., Guan Y. and Peiris J.S.M., Hyperinduction of Cyclooxygenase-2-Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection, The Journal of Infectious Diseases. 2008, 198(4): 525-35.

Li O.T.W., Chan M.C.W., Leung C.S.W., Chan W.Y., Guan Y., Nicholls J.M. and Poon L.L.M., Full factorial analysis of Mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation., In: Li OT, Chan MC, Leung CS, Chan RW, Guan Y, Nicholls JM, Poon LL., PLoS ONE. 2009, 21;4(5): e5658.

Luo W., Chen Y., Wang M., Chen Y., Zheng Z., Song H., Chen H., Guan Y., Ng M.H., Zhang J. and Xia N., Peptide mimics of a conserved H5N1 avian influenza virus neutralization site, Biochem. J.. 2009, 419: 133-139.

Nicholls J.M., Chan M.C.W., Chan W.Y., Cheung C.Y., Kwong D.L.W., Wong M.P., Poon L.L.M., Tsao G.S.W. and Guan Y., 2008 Research Output Prize/Faculty Outstanding Research Output Award, The University of Hong Kong. 2008.

Nicholls J.M., Peiris J.S.M. and Guan Y., Sialic acid and receptor expression on the respiratory tract in normal subjects and H5N1 and non-avian influenza patients, Hong Kong Medical Journal. 2009, 15(3 Suppl 4): 16-20.

Owoade A.A., Ducatez M.F., Hubschen J.M., Sausy A., Chen H., Guan Y. and Muller C.P., Avian metapneumovirus subtype A in China and subtypes A and B in Nigeria, Avian Dis.. 2008, 52: 502-6.

Peiris J.S.M., Poon L.L.M. and Guan Y., Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans., J Clin Virol. . 2009, 45: 169-73.

Peiris J.S.M., Poon L.L.M., Nicholls J.M. and Guan Y., The role of influenza virus gene constellation and viral morphology on cytokine induction, pathogenesis, and viral virulence, Hong Kong Medical Journal. 2009, 15(3 Suppl 4): 21-3.

Poon L.L.M., Chan K.H., Leung C.S.W., Smith G.J., Guan Y., Yuen K.Y. and Peiris J.S.M., Molecular Detection of a Novel Human Influenza (H1N1) of Pandemic Potential by Conventional and Real-Time Quantitative RT-PCR Assays, Clinical Chemistry. 2009, 55: 1555-1558.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Smith G.J., Dhanasekaran V., Bahl J., Lycett S.J., Worobey M., Pybus O.G., Ma S.K., Cheung C.L., Raghwani J., Bhatt S., Peiris J.S.M., Guan Y. and Rambaut A., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Nature. UK, Nature, 2009, 459: 1122-1125.

Throsby M., van den Brink E., Jongeneelen M., Alard P., Cornelissen L., Bakker A., Cox F., van Deventer E., Guan Y., Cinatl J., ter Meulen J., Lasters I., Carsetti R., Peiris J.S.M., de Kruif J. and Goudsmit J., Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells., PLoS One.. 2008, 3: e3942.

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Zhang Z., Zhang J., Huang K., Li K.S., Yuen K.Y., Guan Y., Chen H. and Ng W.F., Systemic infection of avian influenza A virus H5N1 subtype in human, Human Pathology. 2009, 40: 735-739.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Zheng B., Guan Y., Huang J. and He M.L., Synthetic Peptide Targeting Critical Sites on the SARS-Associated Coronaviurs Spike Protein Responsible for Viral Infection and a Method of Use Thereof, U.S. Patent No. 7,491,489. 2009.

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

Researcher : He ML

List of Research Outputs

Zheng B., Guan Y., Huang J. and He M.L., Synthetic Peptide Targeting Critical Sites on the SARS-Associated Coronaviurs Spike Protein Responsible for Viral Infection and a Method of Use Thereof, U.S. Patent No. 7,491,489. 2009.

Researcher : Ho PL

List of Research Outputs

Chang K.C., Leung C.C., Yew W.W., Lam F.M., Ho P.L., Chau C.H., Cheng V.C.C. and Yuen K.Y., Analyses of fluoroquinolones and Clostridium difficile-associated diarrhoea in tuberculosis patients., The international journal of tuberculosis and lung disease. 2009, 13(3): 341-346.

Cheng V.C.C., Yam W.C., Chan J.F.W., To K.K.W., Ho P.L. and Yuen K.Y., Clostridium difficile ribotype 027 arrives in Hong Kong., International Journal of Antimicrobial Agents. 2009, 54(5): 492-493.

Cheng V.C.C., Chan J.F.W., To K.K.W., Tai J.W.M. and Ho P.L., Detection of community-associated MRSA as a result of the unmasking effect of antibiotic treatment., Journal of Hospital Infection. 2009, 72: 273-4.

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

Ho P.L., Yip K.S., Chow K.H., Lo J.Y., Que T.L., Yuen K.Y. and Yuen K.Y., Antimicrobial resistance among uropathogens that cause acute uncomplicated cystitis in women in Hong Kong: a prospective multicenter study in 2006 to 2008., Diagnostic Microbiology and Infectious Disease. 2009.

Ho P.L., Wong R.C., Chow K.H., Yip K., Wong S.S.Y. and Que T.L., CTX-M type beta-lactamases among fecal Escherichia coli and Klebsiella pneumoniae isolates in non-hospitalized children and adults., Journal of Microbiology, Immunology and Infection. 2008, 41: 428-32.

Ho P.L., Chow K.H., Lo P.Y., Lee K.F. and Lai E.L.Y., Changes in the epidemiology of methicillin-resistant Staphylococcus aureus associated with spread of the ST45 lineage in Hong Kong., Diagnostic Microbiology and Infectious Disease. 2009, 64: 131-7.

Ho P.L., Wong M.P., Lai E.L.Y., Chan K.H. and Chiu S.S.S., DNA typing of cytological samples for retrospective identification of an early case of Panton-Valentine leucocidin-positive, community-associated methicillin-resistant Staphylococcus aureus pneumonia, J Clin Microbiol. 2008, 46: 2457-2458.

Ho P.L., Cheng V.C.C. and Chow K.H., Decreasing prevalence of levofloxacin-resistant Streptococcus pneumoniae in Hong Kong, 2001 to 2007., Journal of Antimicrobial Chemotherapy. 2009, 63: 836-8.

Ho P.L., Fluoroquinolone resistance in Streptococcus pneumoniae. , In: Dr. P.L.Ho, 11th Western Pacific Congress on Chemotherapy and Infectious Diseases . Taipei Internaitonal Convention Center, WPCCID, 2008.

Ho P.L., Hospital antibiotic poloicies., In: Dr. P.L.Ho, 11th Western Pacific Congress on Chemotherapy and Infectious Diseases . WPCCID, Taipei Internaitonal Convention Center, 2008.

Ho P.L., MRSA-from community ot hospital., In: Dr. P.L.Ho, Hong Kong College of Anaesthesiologist, & The Society of Anaesthetisits of Hong Kong - Hong Kong Annual Scientific Meeting in Anaesthesiology 2008 . Hong Kong Convention and Exhibition centre, 2008.

Ho P.L., Microbiology and antimicrobial resistance in recurrent urinary tract infection , In: Dr. P.L.Ho, The Langham Hong Kong Hotel, Association of Private Medical Specialists of Hong Kong, 2008.

Ho P.L., Pandemic influenza. , In: Dr. P.L.Ho, WONCA 2009 Asia-Pacific Regional Conference . Hong Kong Convention & Exhibition Centre, WONCA, 2009.

Ho P.L., Symposium on Antibacterials. , In: Dr. P.L.Ho, 11th Western Pacific Congress on Chemotherapy and Infectious Diseases . Taipei Internaitonal Convention Center, WPCCID, 2008.

Lam T.P., Ho P.L., Lam K.F., Choi K. and Yung R., Use of antibiotics by primary care doctors in Hong Kong, In: Lam TP, Ho PL, Lam KF, Choi K, Yung R, Asia Pacific Family Medicine. 2009, 8(1): 5.

Lam T.P., Ho P.L., Lam K.F., Choi K. and Yung R., Use of antibiotics by primary care doctors in Hong Kong, Wonca Asia Pacific Conference, Melbourne, Australia. 2008.

Lee C.K., Ho P.L., Lee K.Y., Tsui G.T., Chua E., Tsoi W.C. and Lin C.K., Value of anaerobic culture in bacterial surveillance program for platelet concentrates., Transfusion. 2008, 48: 2606-11.

Researcher : Huang K

List of Research Outputs

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Zhang Z., Zhang J., Huang K., Li K.S., Yuen K.Y., Guan Y., Chen H. and Ng W.F., Systemic infection of avian influenza A virus H5N1 subtype in human, Human Pathology. 2009, 40: 735-739.

Researcher : Huang K

List of Research Outputs

Zhang Z., Zhang J., Huang K., Li K.S., Yuen K.Y., Guan Y., Chen H. and Ng W.F., Systemic infection of avian influenza A virus H5N1 subtype in human, Human Pathology. 2009, 40: 735-739.

Researcher : Huang Y

List of Research Outputs

Woo P.C.Y., Lau S.K.P., Huang Y. and Yuen K.Y., Coronavirus diversity, phylogeny and interspecies jumping., Experimental biology and medicine (Maywood, N.J.). 2009, 234(10): 1117-1127.

Woo P.C.Y., Lau S.K.P., Yip C.Y., Huang Y. and Yuen K.Y., More and More Coronaviruses: Human Coronavirus HKU1, Viruses. 2009, 1(1): 57-71.

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Researcher : Hui PY

List of Research Outputs

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y., Poon L.L.M., Guan Y., Ip N.Y.Y., Lau A.S.Y. and Peiris J.S.M., Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK, The Journal of Immunology. 2009, 182: 1088-1098.

Hui P.Y., Innate Immune Responses and Signaling Pathways in Influenza A (H5N1) Infected Human Primary Macrophages, The University of Hong Kong. 2008.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y. and Peiris J.S.M., Signaling Pathways Associated with H5N1-induced Cytokines and Chemokines, Gordon Research Conferences. 2009.

Hui P.Y., Lee M.Y., Cheung C.Y. and Peiris J.S.M., The role of interferon regulatory factor 3 and p38 in influenza a virus induced pro-inflammatory cytokines, CYTOKINE. 2008, 43(3): 259.

Lee M.Y., Cheung C.Y., Nicholls J.M., Hui P.Y., Leung C.Y.H., Uiprasertkul M., Tipoe G.L., Lau Y.L., Poon L.L.M., Ip N.Y., Guan Y. and Peiris J.S.M., Hyperinduction of Cyclooxygenase-2-Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection, The Journal of Infectious Diseases. 2008, 198(4): 525-35.

Researcher : Kao RYT

List of Research Outputs

Kao R.Y.T., New Druggable Targets, Novel Anti-flu Agents , World Summit Of Antivirals 2008 . 2008.

Leung K.Y., Yeung K.W.K., Kao R.Y.T., Chu P.K. and Cheung K.M.C., An anti-bacterial coating in dental implant used in orthopaedics/ feasibility study of anti-bacterial coating in dental implant for orthopaedic use, SICOT/SIROT 2008 XXIV Triennial World Congress, Hong Kong (Aug 24-28, 2008). 2008.

Leung K.Y., Yeung K.W.K., Kao R.Y.T., Chu P.K. and Cheung K.M.C., An anti-bacterial coating in dental implant used in orthopaedics/feasibility study of anti-bacterial coating in detnal implant for orthopaedic use, SICOT/SIROT 2008 XXIV Triennial World Congress, Hong Kong, August 24-28, 2008.

Leung K.Y., Yeung K.W.K., Kao R.Y.T., Chu P.K. and Cheung K.M.C., Optimal local dosage of housekeeping antibiotics to inhibit S. aureus without inducing osteoblast necrosis: in vitro study, SICOT/SIROT 2008 XXIV Triennial World Congress, Hong Kong, August 24-28, 2008.

Leung K.Y., Yeung K.W.K., Kao R.Y.T., Chu P.K. and Cheung K.M.C., Optimal local dosage of housekeeping antibiotics to inhibit s. aureus without inducing osteoblast necrosis: in vitro study., SICOT/SIROT 2008 XXIV Triennial World Congress, Hong Kong (Aug 24-28, 2008). 2008.

Tsui Y.K., Leung Y.L., Kao R.Y.T., Masuda K., Chan D. and Cheung K.M.C., Identifying therapeutic chemical agents for osteoarthritis by high throughput screening, 55th Annual Meeting of the Orthopaedic Research Society, Las Vegas, USA, February 22-25, 2009.

Yeung K.W.K., Cheung K.M.C., Luk K.D.K., Yeung C.Y., Kao R.Y.T. and Chu P.K., Antibacterial surface and method of fabrication (No.: 61/154,278 & 61/153,840), U.S. Provisional Patent. 2009.

Researcher : Lai ACK

List of Research Outputs

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Researcher : Lai ELY

List of Research Outputs

Ho P.L., Chow K.H., Lo P.Y., Lee K.F. and Lai E.L.Y., Changes in the epidemiology of methicillin-resistant Staphylococcus aureus associated with spread of the ST45 lineage in Hong Kong., Diagnostic Microbiology and Infectious Disease. 2009, 64: 131-7.

Ho P.L., Wong M.P., Lai E.L.Y., Chan K.H. and Chiu S.S.S., DNA typing of cytological samples for retrospective identification of an early case of Panton-Valentine leucocidin-positive, community-associated methicillin-resistant Staphylococcus aureus pneumonia, J Clin Microbiol. 2008, 46: 2457-2458.

Researcher : Lam HY

List of Research Outputs

Chen J.H.K., Wong K.H., Li P., Chan K.C.W., Lee M.P., Lam H.Y., Cheng V.C.C., Yuen K.Y. and Yam W.C., Molecular Epidemiological Study of HIV-1 CRF01_AE Transmission in Hong Kong , In: David D. Ho, MD, Paul A. Volberding, MD, William A. Blattner, MD, Journal of Acquired Immune Deficiency Syndromes. Wolters Kluwer, Lippincott Williams & Wilkins, 2009, 51: 530-535.

Researcher : Lau SKP

List of Research Outputs

Chan C.M., Tse H., Wong S.S.Y., Woo P.C.Y., Lau S.K.P., Chen L., Zheng B., Huang J. and Yuen K.Y., Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. , J Clin Virol. 2009, 45(1): 54-60.

Chan C.M., Lau S.K.P., Woo P.C.Y., Tse H., Zheng B., Chen L., Huang J. and Yuen K.Y., Identification of Major Histocompatibility Antigen Class I C as an attachment coreceptor that facilitates Coronavirus HKU1 Spike-mediated infection, J Viral . 2009, 16(1): 45-52.

Chan C.M., Woo P.C.Y., Lau S.K.P., Tse H., Chen H., Li F., Zheng B., Chen L., Huang J. and Yuen K.Y., Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection, Exp Biol Med (Maywood). 2008, 33 (12): 1527-1536.

Lau S.K.P., Li K.S.M., Chau K.Y., So L.Y., Lee R.A., Lau Y.L., Chan K.H., Lim W.W.L., Woo P.C.Y. and Yuen K.Y., Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A, Journal of Clinical Microbiology. 2009, 47(5): 1549-1552.

Lau S.K.P., Current Management of Urinary Tract Infections, Postgraduate Diploma in Diagnosis and Therapeutics in Internal Medicine, HKU . 2008.

Lau S.K.P., Discovery and characterization of novel coronaviruses., Diagnosis and Research for Emerging Viral Infections. Chang Gung University, Taipei.. 2008.

Lau S.K.P., Discovery of the Hokovirus, Emerging Infectious Diseases Symposium (Taipei). 2008.

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Lau S.K.P., SARS coronavirus: from human to civet and bat., Frontier in Biomedical Research . 2008.

Lau S.K.P., The discovery of novel bat coronaviruses., Center for Disease Control, Taipei.. 2008.

Woo P.C.Y., Lau S.K.P., Huang Y. and Yuen K.Y., Coronavirus diversity, phylogeny and interspecies jumping., Experimental biology and medicine (Maywood, N.J.). 2009, 234(10): 1117-1127.

Woo P.C.Y., Teng L.L., Tsang K.L., Tse H., Tsang V.Y.M., Chan K.M., Lee E.K.Y., Chan J.K.H., Tam D.M.W., Chung L.M.W., Lau S.K.P. and Yuen K.Y., Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea, BMC Microbiology. 2009, 9: 21.

Woo P.C.Y., Lau S.K.P., Yip C.Y., Huang Y. and Yuen K.Y., More and More Coronaviruses: Human Coronavirus HKU1, Viruses. 2009, 1(1): 57-71.

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Woo P.C.Y., Teng L.L., Tsang S.N.Y., Tse C.W.S., Lau S.K.P. and Yuen K.Y., The oral cavity as a natural reservoir for Streptococcus sinensis, Clinical Microbiology And Infection. 2008, 14: 1075-1079.

Woo P.C.Y., Lau S.K.P., Teng L.L., Tse H. and Yuen K.Y., Then and now: use of 16S rDNA gene sequencing for bacterial identification and discovery of novel bacteria in clinical microbiology laboratories, Clinical Microbiology and Infection. 2008, 14: 908-34.

Researcher : Lee KF

List of Research Outputs

Ho P.L., Chow K.H., Lo P.Y., Lee K.F. and Lai E.L.Y., Changes in the epidemiology of methicillin-resistant Staphylococcus aureus associated with spread of the ST45 lineage in Hong Kong., Diagnostic Microbiology and Infectious Disease. 2009, 64: 131-7.

Researcher : Lee MY

List of Research Outputs

Cheung C.Y., Lee M.Y. and Peiris J.S.M., Induction of pro-inflammatory mediators by H5N1 infection of primary human lung microvascular endothelial cells, CYTOKINE. 2008, 43(3): 259.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y., Poon L.L.M., Guan Y., Ip N.Y.Y., Lau A.S.Y. and Peiris J.S.M., Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK, The Journal of Immunology. 2009, 182: 1088-1098.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y. and Peiris J.S.M., Signaling Pathways Associated with H5N1-induced Cytokines and Chemokines, Gordon Research Conferences. 2009.

Hui P.Y., Lee M.Y., Cheung C.Y. and Peiris J.S.M., The role of interferon regulatory factor 3 and p38 in influenza a virus induced pro-inflammatory cytokines, CYTOKINE. 2008, 43(3): 259.

Lee M.Y., Cheung C.Y., Nicholls J.M. and Peiris J.S.M., Hyper-induction of COX-2-medicated proinflammatory cascade: A mechanism for the pathogenesis of avian influenza H5N1 infection , CYTOKINE. 2008, 43(3): 259.

Lee M.Y., Cheung C.Y., Nicholls J.M., Hui P.Y., Leung C.Y.H., Uiprasertkul M., Tipoe G.L., Lau Y.L., Poon L.L.M., Ip N.Y., Guan Y. and Peiris J.S.M., Hyperinduction of Cyclooxygenase-2-Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection, The Journal of Infectious Diseases. 2008, 198(4): 525-35.

Researcher : Lee SS

List of Research Outputs

Lee S.S., Tam D.K., Tan Y., Mak W.L., Wong K.H., Chen J.H.K. and Yam W.C., An exploratory study on the social and genotypic clustering of HIV infection in men having sex with men, In: JA Levy, AIDS. Lippincott Williams & Wilkins, 2009, 23: 1755-1764.

Zheng B., Zhao X., Lee S.S., Wong K.H., Chan K.C.W., Ng F., Yam W.C. and Yuen K.Y., Study of Polymorphisms in HIV-1 Co-receptors and Their Ligands in Chinese Population and Their Effects on HIV-1 Infection, XVII International AIDS Conference. Mexico City, Mexico, 2008.

Researcher : Leung CSW

List of Research Outputs

Li O.T.W., Chan M.C.W., Leung C.S.W., Chan W.Y., Guan Y., Nicholls J.M. and Poon L.L.M., Full factorial analysis of Mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation., In: Li OT, Chan MC, Leung CS, Chan RW, Guan Y, Nicholls JM, Poon LL., PLoS ONE. 2009, 21;4(5): e5658.

Poon L.L.M., Chan K.H., Leung C.S.W., Smith G.J., Guan Y., Yuen K.Y. and Peiris J.S.M., Molecular Detection of a Novel Human Influenza (H1N1) of Pandemic Potential by Conventional and Real-Time Quantitative RT-PCR Assays, Clinical Chemistry. 2009, 55: 1555-1558.

Researcher : Leung CYH

List of Research Outputs

Bahl J., Leung C.Y.H., Smith G.J., Ellis T., Dyrting K.C., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of viruses isolated from wild birds in Hong Kong, NIAID Centers of Excellence for influenza Research and Surveillance, 3rd Annual CEIRS Network Meeting . 2009.

Lee M.Y., Cheung C.Y., Nicholls J.M., Hui P.Y., Leung C.Y.H., Uiprasertkul M., Tipoe G.L., Lau Y.L., Poon L.L.M., Ip N.Y., Guan Y. and Peiris J.S.M., Hyperinduction of Cyclooxygenase-2-Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection, The Journal of Infectious Diseases. 2008, 198(4): 525-35.

Poon L.L.M., Leung C.Y.H., Nicholls J.M., Lichy J.H., Yamamoto M., Waldmann T.A., Peiris J.S.M. and Perera L.P., Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice, The Jounal of Immunology. 2009, 182(5): 3063-71.

Santhia K., Ramy A., Jayaningsih P., Samaan G., Dibia N., Sulaimih C., Joni G., Leung C.Y.H., Sriyal J., Peiris J.S.M., Wandra T. and Kandun N., Avian Influenza A H5n1 Infections In Bali Province, Indonesia: A Behavioral, Virological And Seroepidemiological Study., Influenza Other Respi Viruses. 2009, 3(3): 81-89.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Researcher : Li KSM

List of Research Outputs

Lau S.K.P., Li K.S.M., Chau K.Y., So L.Y., Lee R.A., Lau Y.L., Chan K.H., Lim W.W.L., Woo P.C.Y. and Yuen K.Y., Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A, Journal of Clinical Microbiology. 2009, 47(5): 1549-1552.

Researcher : Li L

List of Research Outputs

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

Researcher : Li OTW

List of Research Outputs

Li O.T.W., Chan M.C.W., Leung C.S.W., Chan W.Y., Guan Y., Nicholls J.M. and Poon L.L.M., Full factorial analysis of Mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation., In: Li OT, Chan MC, Leung CS, Chan RW, Guan Y, Nicholls JM, Poon LL., PLoS ONE. 2009, 21;4(5): e5658.

Li O.T.W. and Poon L.L.M., Influenza Polymerase Subunits Compatibility between H1 and H5 viruses, XIV. International Congress of Virology . 2008.

Researcher : Li SMK

List of Research Outputs

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Researcher : Li WS

List of Research Outputs

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

Researcher : Lim WWL

List of Research Outputs

Wang W., Ren P., Mardi S., Mardi S., Hou L., Tsai C., Chan K.H., Cheng P., Sheng J., Buchy P., Sun B., Toyoda T., Lim W.W.L., Peiris J.S.M., Zhou P. and Deubel V., Design of multiplexed detection assays for identification of avian influenza a virus subtypes pathogenic to humans by SmartCycler real-time reverse transcription-PCR, Journal of Clinical Microbiology. 2008, 47(1): 86-92.

Researcher : Lin T

List of Research Outputs

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Researcher : Lin Y

List of Research Outputs

Lin Y., Shum K.T., Tanner J.A. and Zheng B., In vitro selection of DNA aptamers binding H5N1 Virus nucleoprotein, HKU 13th Research Postgraduate Symposium. 2008.

Xu K., Zheng B., Zeng R., Lu W., Lin Y., Xue L., Li L., Yang L.L., Xu C., Dai J., Wang F., Li Q., Dong Q.X., Yang R.F., Wu J.R. and Sun B., Severe Acute Respiratory Syndrome Coronavirus Accessory Protein 9b Is a Virion-Associated Protein. , Virology . 2009, 388(2): 279-85.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., He Y., Jiang S., Wu C., Jin D., Zhou Y. and Yuen K.Y., SARS-CoV S Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection. , Vaccine 2nd Congress. Boston, MA, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Researcher : Lin Y

List of Research Outputs

Lin Y., Shum K.T., Tanner J.A. and Zheng B., In vitro selection of DNA aptamers binding H5N1 Virus nucleoprotein, HKU 13th Research Postgraduate Symposium. 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Researcher : Lo PY

List of Research Outputs

Ho P.L., Chow K.H., Lo P.Y., Lee K.F. and Lai E.L.Y., Changes in the epidemiology of methicillin-resistant Staphylococcus aureus associated with spread of the ST45 lineage in Hong Kong., Diagnostic Microbiology and Infectious Disease. 2009, 64: 131-7.

Researcher : Ma S

List of Research Outputs

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., He Y., Jiang S., Wu C., Jin D., Zhou Y. and Yuen K.Y., SARS-CoV S Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection. , Vaccine 2nd Congress. Boston, MA, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Researcher : Ma SK

List of Research Outputs

Garcia J., Lagarde N.J.C., Ma S.K., de Jong M., Buchy P. and Peiris J.S.M., Optimization and evaluation of an influenza A (H5) pseudotyped lentiviral particle – based serological assay., Ho Chin Minh City, Pasteur International forum. 2009.

Smith G.J., Dhanasekaran V., Bahl J., Lycett S.J., Worobey M., Pybus O.G., Ma S.K., Cheung C.L., Raghwani J., Bhatt S., Peiris J.S.M., Guan Y. and Rambaut A., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Nature. UK, Nature, 2009, 459: 1122-1125.

Researcher : Mok BWY

List of Research Outputs

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Researcher : Ng F

List of Research Outputs

Zeng Y., Zhou J., Chen D., Poon K.M., Ng F., Yuen K.Y. and Zheng B., A SNP in IFNGR1 promoter is correlated to the susceptibility to chronic HBV infection in Chinese population, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zeng Y., Chan K.C.W., Chan C.S., Ng F., Wong K.H. and Zheng B., Detection of HIV specific cytotoxic T lymphocytes viral delivery system, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zheng B., Zhao X., Lee S.S., Wong K.H., Chan K.C.W., Ng F., Yam W.C. and Yuen K.Y., Study of Polymorphisms in HIV-1 Co-receptors and Their Ligands in Chinese Population and Their Effects on HIV-1 Infection, XVII International AIDS Conference. Mexico City, Mexico, 2008.

Zhou J., Chen D., Poon K.M., Zeng Y., Ng F., Lu L., Huang J., Yuen K.Y. and Zheng B., A comprehensive study of interferon-γ receptor 1 gene polymorphisms and susceptibility to chronic hepatitis B virus infection. , Immunogenetics. 2009, 61(6): 423-430.

Zhou J., Smith D.K., Lu L., Poon K.M., Ng F., Chen D., Huang J., Yuen K.Y. and Zheng B., A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection, J Viral Hepat. 2009, 16(1): 45-52.

Researcher : Ng IHY

List of Research Outputs

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y., Poon L.L.M., Guan Y., Ip N.Y.Y., Lau A.S.Y. and Peiris J.S.M., Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK, The Journal of Immunology. 2009, 182: 1088-1098.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y. and Peiris J.S.M., Signaling Pathways Associated with H5N1-induced Cytokines and Chemokines, Gordon Research Conferences. 2009.

Researcher : Ng SF

List of Research Outputs

Ng S.F. and Poon L.L.M., Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans, XIV International Congress of Virology. 2008.

Researcher : Peiris JSM

List of Research Outputs

Bahl J., Leung C.Y.H., Smith G.J., Ellis T., Dyrting K.C., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of viruses isolated from wild birds in Hong Kong, NIAID Centers of Excellence for influenza Research and Surveillance, 3rd Annual CEIRS Network Meeting . 2009.

Chen Y., Qin K., Wu W.L., Li G., Zhang J., Du H., Ng M.H., Shih W.K., Peiris J.S.M., Guan Y., Chen H. and Xia N., Broad Cross Protection Against H5N1 Avian Influenza Infection by Means of Monoclonal Antibodies that Map to conserved viral Epitopes, The Journal of Infectious Diseases. 2009, 199: 49-58.

Cheng K.Y., Cowling B.J., Fang J., Chan K.H., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Effects of oseltamivir on severity and duration of symptoms, viral shedding, and infectivity of influenza (abstract), Hong Kong College of Community Medicine 2008 Annual Scientific Meeting, 27 September 2008, Hong Kong. Hong Kong, Hong Kong College of Community Medicine, 2008, Poster 23.

Chiu S.S.S., Chan K.H., Tu W., Lau Y.L. and Peiris J.S.M., Immunogenicity and safety of intradermal versus intramuscular route of influenza immunization in infants less than 6 months of age: a randomized controlled trial, Vaccine. 2009, doi:10.1016: J.vaccine.2009.05.066.

Chu K.W., Poon L.L.M., Guan Y. and Peiris J.S.M., Novel astroviruses in insectivorous bats. , Journal of Virology. 2008, 82: 9107-9114.

Cowling B.J., Leung G.M., Peiris J.S.M., Chan K.H., Yung R.W.H. and Seto W.H., A controlled trial of masks and hand hygiene for reducting influenza transmission, The University of Hong Kong (abstract), CDC Nonpharmaceutical Interventions for Pandemic Influenza PI Meeting, 4-6 March 2009, Atlanta. Atlanta, Centres for Disease Control and Prevention, 2009, 19-20.

Cowling B.J., Fung R.O.P., Fang J., Cheng K.Y., Lam C.L.K., Chan K.H., Seto W.H., Yung R., Chu D.W.S., Lee P., Chiu M.C., Lee H.C., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., A randomized trial of face masks and hand hygiene to prevent influenza transmission in households (abstract) (poster presentation), Third European Influenza Conference, 14-17 September 2008, Vilamoura, Portugal. Vilamoura, Portugal, European Scientific Working group on Influenza, 2008, 116.

Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Effects of antiviral son severity and duration of symptoms, viral shedding, and household transmission of influenza (abstract) (poster presentation), Third European Influenza Conference, 14-17 September 2008, Vilamoura, Portugal. Vilamoura, Portugal, European Scientific Working group on Influenza, 2008, 162.

Cowling B.J., Lau E.H.Y., Lam C.L.H., Cheng K.Y., Kovar J., Chan K.H., Peiris J.S.M. and Leung G.M., Effects of school closures, 2008 winter influenza season, Hong Kong, Emerging Infectious Diseases. 2008, 14(10): 1660-1662.

Cowling B.J., Fang J., Riley S., Peiris J.S.M. and Leung G.M., Estimates of the serial interval of influenza using laboratory-confirmed natural infections in households (abstract), 1st International Conference on Infectious Diseases Dynamics, 1-3 December 2008, Asilomar, USA. Asilomar, USA, Elsevier, 2008, P2.15.

Cowling B.J., Fang J., Riley S., Peiris J.S.M. and Leung G.M., Estimating the serial interval of influenza from natural infections in households (abstract), Third European Influenza Conference, 14-17 September 2008, Vilamoura, Portugal. Vilamoura, Portugal, European Scientific Working group on Influenza, 2008, 60.

Cowling B.J., Fang J., Riley S., Peiris J.S.M. and Leung G.M., Estimation of the serial interval of influenza, Epidemiology. 2009, 20(3): 344-347.

Cowling B.J., Chan K.H., Fang J., Cheng K.Y., Fung R.O.P., Lim Wai W.S., Sin J.W.F., Seto W.H., Yung R.W.H., Chu D.W.S., Chiu B.C.F., Lee P.W.Y., Chiu M.C., Lee H.C., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Findings of a cluster randomized controlled trial of face masks and hand hygiene to prevent influenza transmission in households (abstract and oral presentation), XI International Symposium on Respiratory Viral Infections, 19-22 February 2009, Bangkok, Thailand. Bangkok, Thailand, The Macrae Group LLC, 2009, I-2.

Desvaux S., Marx N., Ong S., Gaidet N., Hunt M., Manuguerra J.C., Sorn S., Peiris J.S.M., Van der Werf S. and Reynes J.M., Highly pathogenic avian influenza virus (H5N1) outbreak in captive wild birds and cats, Cambodia, Emerging Infectious Diseases. 2009, 15(3): 475-8.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Epstein C.R., Yam W.C., Peiris J.S.M. and Epstein R., Methicillin-resistant commensal staphylococci in healthy dogs as a potential zoonotic reservoir for community-acquired antibiotic resistance , Infection, Genetics and Evolution . 2009, 9(2): 283-5.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y., Poon L.L.M., Guan Y., Ip N.Y.Y., Lau A.S.Y. and Peiris J.S.M., Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK, The Journal of Immunology. 2009, 182: 1088-1098.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y. and Peiris J.S.M., Signaling Pathways Associated with H5N1-induced Cytokines and Chemokines, Gordon Research Conferences. 2009.

Hui P.Y., Lee M.Y., Cheung C.Y. and Peiris J.S.M., The role of interferon regulatory factor 3 and p38 in influenza a virus induced pro-inflammatory cytokines, CYTOKINE. 2008, 43(3): 259.

Kovar J., Cowling B.J., Fang J., Chang K.H., Peiris J.S.M., Bermingham A., Edmunds J., Johnson A., McMichael A., Nazareth I., Nguyen-Van-Tam J.S., Watson J.M., Zambon M., Hayward A.C. and Leung G.M., Predictive accuracy of different clinical definitions of influenza in the community setting (abstract) (poster presentation), Third European Influenza Conference, 14-17 September 2008, Vilamoura, Portugal. Vilamoura, Portugal, European Scientific Working group on Influenza, 2008, 114.

Lau L.H.L., Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., The relation between viral shedding and clinical course in natural influenza infections (abstract and poster presentation), XI International Symposium on Respiratory Viral Infections, 19-22 February 2009, Bangkok, Thailand. Bangkok, Thailand, The Macrae Group LLC, 2009, P-9.

Lau L.H.L., Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Peiris J.S.M. and Leung G.M., The time lines of viral shedding and clinical course in influenza infections (abstract), Hong Kong College of Community Medicine Annual Scientific Meeting, 14 June 2009, Hong Kong. Hong Kong, Hong Kong College of Community Medicine, 2009, Poster 26.

Law H.K.W., Cheung C.Y., Sia S.F., Chan Y.O., Peiris J.S.M. and Lau Y.L., Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells, BMC Immunology. 2009, 10: 35.

Lee M.Y., Cheung C.Y., Nicholls J.M. and Peiris J.S.M., Hyper-induction of COX-2-medicated proinflammatory cascade: A mechanism for the pathogenesis of avian influenza H5N1 infection , CYTOKINE. 2008, 43(3): 259.

Lee M.Y., Cheung C.Y., Nicholls J.M., Hui P.Y., Leung C.Y.H., Uiprasertkul M., Tipoe G.L., Lau Y.L., Poon L.L.M., Ip N.Y., Guan Y. and Peiris J.S.M., Hyperinduction of Cyclooxygenase-2-Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection, The Journal of Infectious Diseases. 2008, 198(4): 525-35.

Ng S., Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Effects of oseltamivir treatment on duration of symptoms and viral shedding, and household transmission of influenza virus (abstract and poster presentation), XI International Symposium on Respiratory Viral Infections, 19-22 February 2009, Bangkok, Thailand. Bangkok, Thailand, The Macrae Group LLC, 2009, P-10.

Ng S., Cowling B.J., Cheng K.Y., Fang J., Chan K.H., Peiris J.S.M. and Leung G.M., Treatment of influenza infection with oseltamivir to reduce duration of clinical illness and viral shedding, and household transmission (abstract), Hong Kong College of Community Medicine Annual Scientific Meeting, 14 June 2009, Hong Kong. Hong Kong, Hong Kong College of Community Medicine, 2009, Poster 24.

Nicholls J.M., Peiris J.S.M. and Guan Y., Sialic acid and receptor expression on the respiratory tract in normal subjects and H5N1 and non-avian influenza patients, Hong Kong Medical Journal. 2009, 15(3 Suppl 4): 16-20.

Nicholls J.M., Chan M.C.W., Chan W.Y., Peiris J.S.M., Malakhov M., Li H., Huang Y., Zaltash S., Hawley S., Haslam S., Karamanska R. and Fang F., The use of sialidase treatment in influenza virus infection , XI International Symposium on Respiratory Viral Infections. 2009.

Nicholls J.M. and Peiris J.S.M., Use of DAS181 as a potential therapy for influenza, Sialyoglycobiology 2008, Moscow . 2008.

Peiris J.S.M., In: Session: Influenza Pathogenesis and Host Responses - title: Comparing host responses to H5N1 and seasonal influenza viruses in-vitro: speaker, 3rd Annual CEIRS Network Meeting. USA. 2009.

Peiris J.S.M., Chair Sessions: Tropical Viral infections and Seasonal Influenza, ICAAC. Washington, USA. 2008.

Peiris J.S.M., Chairman for Session: Influenza, HKICNA 3rd International Infection Control Conference. Hong Kong. 1 Sept. 2008. 2008.

Peiris J.S.M., Chairman for session: Replication, Virulence & Impact of Climate Change on Mosquito Borne Viruses, Melbourne ASM 2008, 7-10 Jul. 2008. 2008.

Peiris J.S.M., Chairman, Avian flu - Social and Anthropological Perspectives: Public Health: How to build expert networks with a division of labour? Hong Kong. 2009.

Peiris J.S.M., Chairperson for Opening Keynote Lecture by Professor Robert Webster and Morning Discussion Section, International Symposium of Area of Excellence on Influenza. Hong Kong. 22 Jul. 2008. 2008.

Peiris J.S.M., Congress Chairman, 8th Asia Pacific Congress of Medical Virology (APCMV). Hong Kong. 2009.

Peiris J.S.M. and Poon L.L.M., Detection of SARS coronavirus in humans and animals by conventional and quantitative (real time) reverse transcription polymerase chain reactions., Methods Mol Biol. . Humana Press, 2008, 454: 61-72.

Peiris J.S.M., Poon L.L.M. and Guan Y., Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans., J Clin Virol. . 2009, 45: 169-73.

Peiris J.S.M., Excellence Award Presentation and Symposium: Co-chair-person, 8th Asia Pacific Congress of Medical Virology (APCMV). Hong Kong. 2009.

Peiris J.S.M., Influenza A virus infection of human respiratory epithelium: tissue tropism and innate immune responses, Supervisor of PhD student Chan Wing Yi. 2008.

Peiris J.S.M., Influenza polymerase subunits compatibility between human H1 and H5 viruses, Internal examiner of PhD student Olive Li Tin Wai. 2008.

Peiris J.S.M., Influenza virus - the next pandemic?, ICHAIR Annual Workshop. 2008.

Peiris J.S.M., Keynote lecturer, ESWI. Portugal. 2008.

Peiris J.S.M., Lecture: Emerging Viral Respiratory Diseases in Asia, Specialist Consultation on Emerging Diseases in South-East Asia (SCEDSEA) - Bridging science and society for a health future. Bangkok, Thailand. 2008.

Peiris J.S.M., Lecture: Pandemic flu: predicting the next round, HKICNA 3rd International Infection Control Conference. 2008.

Peiris J.S.M., Lecture: Pathogenesis of Influenza: speaker, 8th Asia Pacific Congress of Medical Virology (APCMV). Hong Kong. 2009.

Peiris J.S.M., Organizer and Chairman, International Symposium of Area of Excellence on Influenza. Hong Kong. July 22, 2008. 2008.

Peiris J.S.M., Plenary Lecture: Viral Challenges to Public Health: Symposium division: Emerging Viruses & Evolution - Lecture: Viral Challenges to Public Health, Melbourne ASM 2008. Melbourne, Australia, 7-10 Jul. 2008. 2008.

Peiris J.S.M., Plenary lecture: Avian Influenza, 11th Western Pacific Congress on Chemotherapy and Infectious Diseases (11th WPCCID). Taiwan. 2008.

Peiris J.S.M., Plenary lecture: Viral Challenges to Public Health. Symposia division: Emerging Viruses & Evolution: Lecture: Avian flu H5N1: Where did it come from and where is it going?, Melbourne ASM 2008, 7-10 Jul. 2008. 2008.

Peiris J.S.M., Scientific Advisory Board Member, XI International Symposium on Respiratory Viral Infections. Bangkok.. 2009.

Peiris J.S.M., Seminar: Bat guano - the gold mine for better understanding of the evolution of coronaviruses:, 3rd International Symposium on Emerging Viral Diseases, Wuhan, China. 2008.

Peiris J.S.M., Session: H5N1 continues to circulatek updates from Lao PDR and Thailand - title: State of the science - questions to be addressed: speaker, 3rd Annual CEIRS Network Meeting. USA. 2009.

Peiris J.S.M., Session: Pathogenesis; Title: Pre-clinical papers literature review - SARS & Influenza; speaker, XI International Symposium on Respiratory Viral Infections. Bangkok. 2009.

Peiris J.S.M. and Poon L.L.M., Severe Acute Respiratory Syndrome (SARS), In: B.W.J. Mahy and M.H.V. Van Regenmortel, Encyclopedia of Virology. UK, Exford: Elsevier, 2008, 4: 552-560.

Peiris J.S.M., Short-term effects of influenza and its interactions with individual factors on mortality in an elderly cohort of Hong Kong, TEC chairman of MPhil student Song Liang. 2009.

Peiris J.S.M., Study of host genetic susceptibility to Severe Acute Respiratory Syndrome (SARS) infection, Co-supervisor of Ph.D. student: Ching Chi Yun Johannes. 2008.

Peiris J.S.M., Symposium: Influenza; Lecture: Pathogenesis of seasonal influenza and avian influenza, 10th Beijing / Hong Kong Medical Exchange: Update on Respiratory Medicine. Hong Kong. 2008.

Peiris J.S.M., Poon L.L.M., Nicholls J.M. and Guan Y., The role of influenza virus gene constellation and viral morphology on cytokine induction, pathogenesis, and viral virulence, Hong Kong Medical Journal. 2009, 15(3 Suppl 4): 21-3.

Peiris J.S.M., Thesis title: Disease burden and seasonality of influenza in subtropical Hong Kong, Co-supervisor of PhD student Yang Lin. 2009.

Peiris J.S.M., Thesis title: H5N1/highly pathogenic avian influenza in Cambodia: evaluating poultry movement and the extent of interaction between poultry and humans, External examiner of PhD student MD Van Kerkhove of School of Hygiene and ropical Medicine, London. 2009.

Peiris J.S.M., Title: Avian flu H5N1: Molecular epidemiology, transmission and pathogenesis: speaker, Genetics and Genomics of Infectious Diseases. Singapore. 2009.

Peiris J.S.M., Title: Avian influenza in humans: impact, surveillance and research: speaker, International Symposium on Viral Respiratory Disease Surveillance. Spain. 2009.

Poon L.L.M. and Peiris J.S.M., Detection of group 1 coronaviruses in bats using universal coronavirus reverse transcription polymerase chain reactions., Methods Mol Biol. . Humana Press, 2008, 454: 13-26.

Poon L.L.M., Chan K.H., Leung C.S.W., Smith G.J., Guan Y., Yuen K.Y. and Peiris J.S.M., Molecular Detection of a Novel Human Influenza (H1N1) of Pandemic Potential by Conventional and Real-Time Quantitative RT-PCR Assays, Clinical Chemistry. 2009, 55: 1555-1558.

Poon L.L.M., Leung C.Y.H., Nicholls J.M., Lichy J.H., Yamamoto M., Waldmann T.A., Peiris J.S.M. and Perera L.P., Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice, The Jounal of Immunology. 2009, 182(5): 3063-71.

Santhia K., Ramy A., Jayaningsih P., Samaan G., Dibia N., Sulaimih C., Joni G., Leung C.Y.H., Sriyal J., Peiris J.S.M., Wandra T. and Kandun N., Avian Influenza A H5n1 Infections In Bali Province, Indonesia: A Behavioral, Virological And Seroepidemiological Study., Influenza Other Respi Viruses. 2009, 3(3): 81-89.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Smith G.J., Dhanasekaran V., Bahl J., Lycett S.J., Worobey M., Pybus O.G., Ma S.K., Cheung C.L., Raghwani J., Bhatt S., Peiris J.S.M., Guan Y. and Rambaut A., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Nature. UK, Nature, 2009, 459: 1122-1125.

Tam H.M., Lee D.C.W., Peiris J.S.M. and Lau A.S.Y., Molecular mechanisms of the hyper-induction of TNF-a by avian influenza virus in human blood macrophages, Frontiers in Immunology Research 2008 International Conference, Florence, Italy, 22-26 July. 2008.

Tam H.M., Lee D.C.W., Law H.Y., Peiris J.S.M. and Lau A.S.Y., Negative regulation of H9N2/G1 virus-activated p38 MAPK by cellular phosphatases, 7th Joint Conference of the International Cytokine Society and the International Society for Interferon and Cytokine Research (abstract published in the “Cytokine” Vol 43 No. 3 September 2008), Montreal, Quebec, Canada, 12-16 October 2008.. 2008.

Tam H.M., Lee D.C.W., Law H.Y., Peiris J.S.M. and Lau A.S.Y., Regulation of avian influenza H9N2/G1 virus-activated p38 MAPK by cellular phosphatases, International Proceedings of 7^th Joint Meeting of the International Cytokine Society and the International Society for Interferon and Cytokine Research. 2008, 99-103.

Tam H.M., Li C.B., Law H.Y., Peiris J.S.M. and Lau A.S.Y., Regulation of avian influenza H9N2/G1virus activated p38 MAPK by cellular phosphatases., International Proceedings of 7th Joint Meeting of the International Cytokine Society and the International Society for Interferon and Cytokine Research.. 2008, 99-103.

Throsby M., van den Brink E., Jongeneelen M., Alard P., Cornelissen L., Bakker A., Cox F., van Deventer E., Guan Y., Cinatl J., ter Meulen J., Lasters I., Carsetti R., Peiris J.S.M., de Kruif J. and Goudsmit J., Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells., PLoS One.. 2008, 3: e3942.

Wang W., Ren P., Mardi S., Mardi S., Hou L., Tsai C., Chan K.H., Cheng P., Sheng J., Buchy P., Sun B., Toyoda T., Lim W.W.L., Peiris J.S.M., Zhou P. and Deubel V., Design of multiplexed detection assays for identification of avian influenza a virus subtypes pathogenic to humans by SmartCycler real-time reverse transcription-PCR, Journal of Clinical Microbiology. 2008, 47(1): 86-92.

Wong C.M., Yang L., Thach T.Q., Chau Y.K., Chan K.P., Thomas G.N., Lam T.H., Wong T.W., Hedley A.J. and Peiris J.S.M., Modification by influenza on health effects of air pollution in Hong Kong, Environmental Health Perspectives. 2009, 117(2): 248-253.

Wong C.M., Ou C., Chan K.P., Chau Y.K., Thach T.Q., Yang L., Chung R.Y.N., Thomas G.N., Peiris J.S.M., Wong T.W., Hedley A.J. and Lam T.H., Social deprivation, air pollution and mortality in Hong Kong: The public health and air pollution in Asia project (PAPA) (powerpoint presentation), Better Air Quality 2008 Workshop, 12-14 November 2008, Bangkok. Bangkok, CAI-Asia Center, 2008.

Wong C.M., Ou C., Chan K.P., Chau Y.K., Thach T.Q., Yang L., Chung R.Y.N., Thomas G.N., Peiris J.S.M., Wong T.W., Hedley A.J. and Lam T.H., The effects of air pollution on mortality in socially deprived urban areas in Hong Kong, China, Environmental Health Perspectives. 2008, 116(9): 1189-1194.

Yen H., Peiris J.S.M. and Peiris J.S.M., Mapping antibody epitopes of the avian H5N1 influenza virus, Public Library of Science (PLoS) Medicine. 2009, 6(4): e1000064.

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

Researcher : Poon KM

List of Research Outputs

Chen J.Y., Chen W.N., Poon K.M., Zheng B., Lin X., Wang Y.X. and Wen Y.M., Interaction between SARS-CoV helicase and a multifunctional cellular protein (Ddx5) revealed by yeast and mammalian cell two-hybrid systems. , Archives of Virology. 2009, 154(3): 507-512.

Siu K.L., Kok K.H., Ng M.H., Poon K.M., Yuen K.Y., Zheng B. and Jin D., Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex., Journal of Biological Chemistry. 2009, 284: 16202-16209.

Zeng Y., Zhou J., Chen D., Poon K.M., Ng F., Yuen K.Y. and Zheng B., A SNP in IFNGR1 promoter is correlated to the susceptibility to chronic HBV infection in Chinese population, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zhou J., Chen D., Poon K.M., Zeng Y., Ng F., Lu L., Huang J., Yuen K.Y. and Zheng B., A comprehensive study of interferon-γ receptor 1 gene polymorphisms and susceptibility to chronic hepatitis B virus infection. , Immunogenetics. 2009, 61(6): 423-430.

Zhou J., Smith D.K., Lu L., Poon K.M., Ng F., Chen D., Huang J., Yuen K.Y. and Zheng B., A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection, J Viral Hepat. 2009, 16(1): 45-52.

Researcher : Poon LLM

List of Research Outputs

An J., Lee D.C.W., Law H.Y., Yang L.H., Poon L.L.M., Lau A.S.Y. and Jones S.J.M., A novel small-molecule inhibitor of the avian influenza H5N1 virus determined through computational screening against the neuraminidase, Journal of Medicinal Chemistry. 2009, 52(9): 2667-2672.

An J., Law H.Y., Lee D.C.W., Yang L.H., Poon L.L.M., Jones S.J.M. and Lau A.S.Y., Identification of a Novel small-molecule inhibitor of avian influenza H5N1 virus through computational screening against neuraminidase, 5^th Congress of Asia Society for Pediatric Research, Hangzhou, Zhejiang, PR China, 21-24 May 2009.

An J., Law H.Y., Lee D.C.W., Yang L.H., Poon L.L.M., Jones S.J.M. and Lau A.S.Y., Novel small-molecule inhibitor of avian influenza H5N1 virus identified through compuational screening against neuraminidase, Second Annual Scientific Meeting. The Hong Kong Society for Paediatric Immunology and Infectious Diseases, Hong Kong, 6 June 2009.

Chu K.W., Poon L.L.M., Guan Y. and Peiris J.S.M., Novel astroviruses in insectivorous bats. , Journal of Virology. 2008, 82: 9107-9114.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Hui P.Y., Lee M.Y., Cheung C.Y., Ng I.H.Y., Poon L.L.M., Guan Y., Ip N.Y.Y., Lau A.S.Y. and Peiris J.S.M., Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK, The Journal of Immunology. 2009, 182: 1088-1098.

Jones S., Lau A.S.Y., An J.H., Law H.Y., Lee D.C.W. and Poon L.L.M., Patent Application Title: Anti-influenza compounds., Type: Provisional. Author form HKU and Type: Co-PI: Steven Jones & Allan SY Lau. Co-I: Jianghong An, Anna Hing-Yee Law, Davy Chun-Wai Lee, Lit-Man Poon. Media: Patent Co-operative Treaty – International Appln No.: CA2009/000133. Owner: HKU Versitech Limited and British Columbia Cancer Agency Branch. Priority date for IP: 04 February 2009.. 2009.

Lee M.Y., Cheung C.Y., Nicholls J.M., Hui P.Y., Leung C.Y.H., Uiprasertkul M., Tipoe G.L., Lau Y.L., Poon L.L.M., Ip N.Y., Guan Y. and Peiris J.S.M., Hyperinduction of Cyclooxygenase-2-Mediated Proinflammatory Cascade: A Mechanism for the Pathogenesis of Avian Influenza H5N1 Infection, The Journal of Infectious Diseases. 2008, 198(4): 525-35.

Li O.T.W., Chan M.C.W., Leung C.S.W., Chan W.Y., Guan Y., Nicholls J.M. and Poon L.L.M., Full factorial analysis of Mammalian and avian influenza polymerase subunits suggests a role of an efficient polymerase for virus adaptation., In: Li OT, Chan MC, Leung CS, Chan RW, Guan Y, Nicholls JM, Poon LL., PLoS ONE. 2009, 21;4(5): e5658.

Li O.T.W. and Poon L.L.M., Influenza Polymerase Subunits Compatibility between H1 and H5 viruses, XIV. International Congress of Virology . 2008.

Ng S.F. and Poon L.L.M., Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans, XIV International Congress of Virology. 2008.

Nicholls J.M., Chan M.C.W., Chan W.Y., Cheung C.Y., Kwong D.L.W., Wong M.P., Poon L.L.M., Tsao G.S.W. and Guan Y., 2008 Research Output Prize/Faculty Outstanding Research Output Award, The University of Hong Kong. 2008.

Peiris J.S.M. and Poon L.L.M., Detection of SARS coronavirus in humans and animals by conventional and quantitative (real time) reverse transcription polymerase chain reactions., Methods Mol Biol. . Humana Press, 2008, 454: 61-72.

Peiris J.S.M., Poon L.L.M. and Guan Y., Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans., J Clin Virol. . 2009, 45: 169-73.

Peiris J.S.M. and Poon L.L.M., Severe Acute Respiratory Syndrome (SARS), In: B.W.J. Mahy and M.H.V. Van Regenmortel, Encyclopedia of Virology. UK, Exford: Elsevier, 2008, 4: 552-560.

Peiris J.S.M., Poon L.L.M., Nicholls J.M. and Guan Y., The role of influenza virus gene constellation and viral morphology on cytokine induction, pathogenesis, and viral virulence, Hong Kong Medical Journal. 2009, 15(3 Suppl 4): 21-3.

Poon L.L.M., Bat guano— the gold mine for better understanding of the evolution of coronaviruses?, The 3rd International Symposium on Emerging Viral Diseases, Wuhan, China. 2008.

Poon L.L.M., Bat guano— the gold mine for better understanding of the evolution of coronaviruses?, XIV International Congress of Virology. 2008.

Poon L.L.M. and Peiris J.S.M., Detection of group 1 coronaviruses in bats using universal coronavirus reverse transcription polymerase chain reactions., Methods Mol Biol. . Humana Press, 2008, 454: 13-26.

Poon L.L.M., Detection of several genetically distinct astroviruses in bats, XIV International Congress of Virology. 2008.

Poon L.L.M., Chan K.H., Leung C.S.W., Smith G.J., Guan Y., Yuen K.Y. and Peiris J.S.M., Molecular Detection of a Novel Human Influenza (H1N1) of Pandemic Potential by Conventional and Real-Time Quantitative RT-PCR Assays, Clinical Chemistry. 2009, 55: 1555-1558.

Poon L.L.M., Seminar: Bat guano - the gold mine for better understanding of the evolution of coronaviruses?, The 14th International Congress of Virology, Istanbul, Turkey. 2008.

Poon L.L.M., Seminar: Detection of several genetically distinct astroviruses in bats, speaker, The 14th International Congress of Virology, Istanbul, Turkey. 2008.

Poon L.L.M., Thesis title: Influenza polymerase subunit compatibility between human H1 and H5 viruses, Supervisor of PhD student Olive Li Tin Wai. 2008.

Poon L.L.M., Top 1% of most cited scientists (Microbiology) , ISI Web of Knowledge. 2008.

Poon L.L.M., Leung C.Y.H., Nicholls J.M., Lichy J.H., Yamamoto M., Waldmann T.A., Peiris J.S.M. and Perera L.P., Vaccinia virus-based multivalent H5N1 avian influenza vaccines adjuvanted with IL-15 confer sterile cross-clade protection in mice, The Jounal of Immunology. 2009, 182(5): 3063-71.

Poon L.L.M., Viruses. 2008.

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

Researcher : Qin K

List of Research Outputs

Chen Y., Qin K., Wu W.L., Li G., Zhang J., Du H., Ng M.H., Shih W.K., Peiris J.S.M., Guan Y., Chen H. and Xia N., Broad Cross Protection Against H5N1 Avian Influenza Infection by Means of Monoclonal Antibodies that Map to conserved viral Epitopes, The Journal of Infectious Diseases. 2009, 199: 49-58.

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Researcher : Qin K

List of Research Outputs

Researcher : Que TL

List of Research Outputs

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

Researcher : Seto WH

List of Research Outputs

Cowling B.J., Leung G.M., Peiris J.S.M., Chan K.H., Yung R.W.H. and Seto W.H., A controlled trial of masks and hand hygiene for reducting influenza transmission, The University of Hong Kong (abstract), CDC Nonpharmaceutical Interventions for Pandemic Influenza PI Meeting, 4-6 March 2009, Atlanta. Atlanta, Centres for Disease Control and Prevention, 2009, 19-20.

Cowling B.J., Fung R.O.P., Fang J., Cheng K.Y., Lam C.L.K., Chan K.H., Seto W.H., Yung R., Chu D.W.S., Lee P., Chiu M.C., Lee H.C., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., A randomized trial of face masks and hand hygiene to prevent influenza transmission in households (abstract) (poster presentation), Third European Influenza Conference, 14-17 September 2008, Vilamoura, Portugal. Vilamoura, Portugal, European Scientific Working group on Influenza, 2008, 116.

Cowling B.J., Chan K.H., Fang J., Cheng K.Y., Fung R.O.P., Lim Wai W.S., Sin J.W.F., Seto W.H., Yung R.W.H., Chu D.W.S., Chiu B.C.F., Lee P.W.Y., Chiu M.C., Lee H.C., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Findings of a cluster randomized controlled trial of face masks and hand hygiene to prevent influenza transmission in households (abstract and oral presentation), XI International Symposium on Respiratory Viral Infections, 19-22 February 2009, Bangkok, Thailand. Bangkok, Thailand, The Macrae Group LLC, 2009, I-2.

Researcher : Shortridge KF

List of Research Outputs

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Researcher : Sia SF

List of Research Outputs

Law H.K.W., Cheung C.Y., Sia S.F., Chan Y.O., Peiris J.S.M. and Lau Y.L., Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells, BMC Immunology. 2009, 10: 35.

Researcher : Smith GJ

List of Research Outputs

Bahl J., Leung C.Y.H., Smith G.J., Ellis T., Dyrting K.C., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of viruses isolated from wild birds in Hong Kong, NIAID Centers of Excellence for influenza Research and Surveillance, 3rd Annual CEIRS Network Meeting . 2009.

Bahl J., Dhanasekaran V., Holmes E.C., Smith G.J. and Guan Y., Gene flow and competitive exclusion in Avian influenza A virus, Epidemics1 – First International conference on Infectious Disease Dynamics. 2008.

Bahl J., Dhanasekaran V., Holmes E.C., Smith G.J. and Guan Y., Gene flow and competitive exclusion of avian influenza A virus. , Virology. 2009, 390: 289-297.

Carrington C.V.F., Foster J.E., Zhu H., Zhang J., Smith G.J., Thompson N., Auguste A.J., Ramkissoon V., Adesiyun A.A. and Guan Y., Detection and phylogenetic analysis of group 1 coronaviruses in South American bats., Emerg Infect Dis.. 2008, 14: 1890-1893.

Dhanasekaran V., Bahl J., Riley S., Duan L., Zhang J., Chen H., Peiris J.S.M., Smith G.J. and Guan Y., Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses, PLoS Pathogens. 2008, 26: e1000161.

Donis R., Smith G.J., Brown I.H., Capua I., Cattoli G., Chen H., Cox N., Davis C.T., Fouchier R.A.M., Garten R., Guan Y., Hay A., Kawaoka Y., Mackenzie J., McCauley J.S.M., Mumford E., Olsen C., Perdue M.L., Russell C.A., Smith C., Smith D., Shu Y., Tashiro M., Dhanasekaran V. and Webster R.G., Continuing progress towards a unified nomenclature for the highly pathogenic H5N1 avian influenza viruses: Divergence of clade 2·2 viruses, Influenza and Other Respiratory Viruses. 2009, 3: 59-62.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Ducatez M., Bahl J., Stigger E., Griffin Y., Webb A., Guan Y., Smith G.J. and Webby R., Generation of ancestral H5N1 influenza viruses as vaccine and diagnostic reagents, The Third International Conference on Influenza Vaccines for the World, Palais des Festivals et des Congres, Cannes Cedex, France. 2009.

Poon L.L.M., Chan K.H., Leung C.S.W., Smith G.J., Guan Y., Yuen K.Y. and Peiris J.S.M., Molecular Detection of a Novel Human Influenza (H1N1) of Pandemic Potential by Conventional and Real-Time Quantitative RT-PCR Assays, Clinical Chemistry. 2009, 55: 1555-1558.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Smith G.J., Ecology and evolution of avian influenza A virus, 5th Pasteur-Asia Virology Course, HKU-Pasteur Research Centre, Hong Kong. 2008.

Smith G.J., Ecology and evolution of avian influenza A virus, Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. 2009.

Smith G.J., Evolution of H5N1 influenza virus in birds, FAO-OIE-WHO Joint Technical Consultation on Avian Influenza at the Human-Animal Interface, Verona, Italy. 2008.

Smith G.J., Molecular epidemiology and evolution of H5N1 HPAI viruses (1996-2009), 7th International Symposium on Avian Influenza, The University of Georgia, Athens, GA, USA. 2009.

Smith G.J., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, 3rd Annual NIAID Centers of Excellence for Influenza Research and Surveillance Network Meeting, Minneapolis, MN, USA. 2009.

Smith G.J., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Emerging Infectious Diseases Program, Duke-NUS Graduate School of Medicine, Singapore. 2009.

Smith G.J., Dhanasekaran V., Bahl J., Lycett S.J., Worobey M., Pybus O.G., Ma S.K., Cheung C.L., Raghwani J., Bhatt S., Peiris J.S.M., Guan Y. and Rambaut A., Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic, Nature. UK, Nature, 2009, 459: 1122-1125.

Smith G.J., Runner-up in Life Sciences, 1st Annual ASAIHL-Scopus Young Scientist Awards, Association of Southeast Asian Institutions of Higher Learning, ASAIHL International Office, Thailand, 2008.

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

Researcher : Song W

List of Research Outputs

Liu N., Song W., Lee K.C., Wang P., Chen H. and Cai Z., Identification of amino acid substitutions in avian influenza virus (H5N1) matrix protein 1 by using nanoelectrospray MS and MS/MS, Journal of the American Society for Mass Spectrometry. 2009, 20: 312-320.

Liu N., Lee K.C., Song W., Wang P., Cai Z. and Chen H., Identification of amino acid substitutions in mutated peptides of nucleoprotein from avian influenza virus, Talanta. 2009, 78: 1492-1496.

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Researcher : Sui H

List of Research Outputs

Lu C.Y., Lu J.H., Chen W.Q., Jiang L.F., Tan B.Y., Ling W.H., Zheng B. and Sui H., Potential infections of H5N1 and H9N2 avian influenza do exist in Guangdong populations of China, Chinese Medical Journal. 2008, 121(20): 2050-2053.

Sui H., Zhao G., Huang J., Jin D., Yuen K.Y. and Zheng B., Small Interfering RNA Targeting M2 Gene Induces Effective and Long term Inhibition of Influenza A Virus Replication. , PloS One. 2009, 4(5): e5671.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., He Y., Jiang S., Wu C., Jin D., Zhou Y. and Yuen K.Y., SARS-CoV S Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection. , Vaccine 2nd Congress. Boston, MA, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Researcher : Tai JWM

List of Research Outputs

Cheng V.C.C., Chan J.F.W., To K.K.W., Tai J.W.M. and Ho P.L., Detection of community-associated MRSA as a result of the unmasking effect of antibiotic treatment., Journal of Hospital Infection. 2009, 72: 273-4.

Researcher : Tang SF

List of Research Outputs

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

Lam M.F., Tang S.F., Tse K.C., Chan D.T.M. and Lai K.N., Ampicillin-sulbactam and amikacin used as second-line antibiotics for patients with culture-negative peritonitis, Peritoneal Dialysis International. 2008, 28: 540-2.

Researcher : Teng LL

List of Research Outputs

Woo P.C.Y., Teng L.L., Tsang K.L., Tse H., Tsang V.Y.M., Chan K.M., Lee E.K.Y., Chan J.K.H., Tam D.M.W., Chung L.M.W., Lau S.K.P. and Yuen K.Y., Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea, BMC Microbiology. 2009, 9: 21.

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Woo P.C.Y., Teng L.L., Tsang S.N.Y., Tse C.W.S., Lau S.K.P. and Yuen K.Y., The oral cavity as a natural reservoir for Streptococcus sinensis, Clinical Microbiology And Infection. 2008, 14: 1075-1079.

Woo P.C.Y., Lau S.K.P., Teng L.L., Tse H. and Yuen K.Y., Then and now: use of 16S rDNA gene sequencing for bacterial identification and discovery of novel bacteria in clinical microbiology laboratories, Clinical Microbiology and Infection. 2008, 14: 908-34.

Researcher : To KKW

List of Research Outputs

Cheng V.C.C., Yam W.C., Chan J.F.W., To K.K.W., Ho P.L. and Yuen K.Y., Clostridium difficile ribotype 027 arrives in Hong Kong., International Journal of Antimicrobial Agents. 2009, 54(5): 492-493.

Cheng V.C.C., Chan J.F.W., To K.K.W., Tai J.W.M. and Ho P.L., Detection of community-associated MRSA as a result of the unmasking effect of antibiotic treatment., Journal of Hospital Infection. 2009, 72: 273-4.

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

Researcher : Tsang KL

List of Research Outputs

Woo P.C.Y., Teng L.L., Tsang K.L., Tse H., Tsang V.Y.M., Chan K.M., Lee E.K.Y., Chan J.K.H., Tam D.M.W., Chung L.M.W., Lau S.K.P. and Yuen K.Y., Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea, BMC Microbiology. 2009, 9: 21.

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Researcher : Tse H

List of Research Outputs

Chan C.M., Tse H., Wong S.S.Y., Woo P.C.Y., Lau S.K.P., Chen L., Zheng B., Huang J. and Yuen K.Y., Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. , J Clin Virol. 2009, 45(1): 54-60.

Chan C.M., Lau S.K.P., Woo P.C.Y., Tse H., Zheng B., Chen L., Huang J. and Yuen K.Y., Identification of Major Histocompatibility Antigen Class I C as an attachment coreceptor that facilitates Coronavirus HKU1 Spike-mediated infection, J Viral . 2009, 16(1): 45-52.

Chan C.M., Woo P.C.Y., Lau S.K.P., Tse H., Chen H., Li F., Zheng B., Chen L., Huang J. and Yuen K.Y., Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection, Exp Biol Med (Maywood). 2008, 33 (12): 1527-1536.

Chan G.S.W., Tsoi H.W., Wong S.S.Y., Li C.L., Tse H., Uni K., Yuen K.Y. and Chan K.W., BK virus nephropathy due to KOM-3 strain., American journal of kidney diseases. 2008, 54(1): 122-126.

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Tse H., A possible way out of the impact-factor game, Nature. 2008, 454: 938-9.

Tse H., “Hokoviruses” and the discovery of other novel pathogens in HK, Department of Microbiology, National University of Singapore. 2008.

Woo P.C.Y., Teng L.L., Tsang K.L., Tse H., Tsang V.Y.M., Chan K.M., Lee E.K.Y., Chan J.K.H., Tam D.M.W., Chung L.M.W., Lau S.K.P. and Yuen K.Y., Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea, BMC Microbiology. 2009, 9: 21.

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Woo P.C.Y., Lau S.K.P., Teng L.L., Tse H. and Yuen K.Y., Then and now: use of 16S rDNA gene sequencing for bacterial identification and discovery of novel bacteria in clinical microbiology laboratories, Clinical Microbiology and Infection. 2008, 14: 908-34.

Researcher : Tsoi HW

List of Research Outputs

Chan G.S.W., Tsoi H.W., Wong S.S.Y., Li C.L., Tse H., Uni K., Yuen K.Y. and Chan K.W., BK virus nephropathy due to KOM-3 strain., American journal of kidney diseases. 2008, 54(1): 122-126.

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Researcher : Wang J

List of Research Outputs

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Researcher : Wang P

List of Research Outputs

Liu N., Song W., Lee K.C., Wang P., Chen H. and Cai Z., Identification of amino acid substitutions in avian influenza virus (H5N1) matrix protein 1 by using nanoelectrospray MS and MS/MS, Journal of the American Society for Mass Spectrometry. 2009, 20: 312-320.

Liu N., Lee K.C., Song W., Wang P., Cai Z. and Chen H., Identification of amino acid substitutions in mutated peptides of nucleoprotein from avian influenza virus, Talanta. 2009, 78: 1492-1496.

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Researcher : Webster RG

List of Research Outputs

Donis R., Smith G.J., Brown I.H., Capua I., Cattoli G., Chen H., Cox N., Davis C.T., Fouchier R.A.M., Garten R., Guan Y., Hay A., Kawaoka Y., Mackenzie J., McCauley J.S.M., Mumford E., Olsen C., Perdue M.L., Russell C.A., Smith C., Smith D., Shu Y., Tashiro M., Dhanasekaran V. and Webster R.G., Continuing progress towards a unified nomenclature for the highly pathogenic H5N1 avian influenza viruses: Divergence of clade 2·2 viruses, Influenza and Other Respiratory Viruses. 2009, 3: 59-62.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Researcher : Wong KH

List of Research Outputs

Chen J.H.K., Wong K.H., Li P., Chan K.C.W., Lee M.P., Lam H.Y., Cheng V.C.C., Yuen K.Y. and Yam W.C., Molecular Epidemiological Study of HIV-1 CRF01_AE Transmission in Hong Kong , In: David D. Ho, MD, Paul A. Volberding, MD, William A. Blattner, MD, Journal of Acquired Immune Deficiency Syndromes. Wolters Kluwer, Lippincott Williams & Wilkins, 2009, 51: 530-535.

Lee S.S., Tam D.K., Tan Y., Mak W.L., Wong K.H., Chen J.H.K. and Yam W.C., An exploratory study on the social and genotypic clustering of HIV infection in men having sex with men, In: JA Levy, AIDS. Lippincott Williams & Wilkins, 2009, 23: 1755-1764.

Zeng Y., Chan K.C.W., Chan C.S., Ng F., Wong K.H. and Zheng B., Detection of HIV specific cytotoxic T lymphocytes viral delivery system, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zheng B., Zhao X., Lee S.S., Wong K.H., Chan K.C.W., Ng F., Yam W.C. and Yuen K.Y., Study of Polymorphisms in HIV-1 Co-receptors and Their Ligands in Chinese Population and Their Effects on HIV-1 Infection, XVII International AIDS Conference. Mexico City, Mexico, 2008.

Researcher : Wong KL

List of Research Outputs

He M.L., Zheng B., Chen Y., Wong K.L., Huang J., Lin M.C., Yuen K.Y., Sung J.J. and Kung H.F., Development of Interfering RNA Agents to Inhibit SARS-associated Coronavirus Infection and Replication, Hong Kong Medical Journal. 2009, Suppl 4: S28-31.

Researcher : Wong KMG

List of Research Outputs

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Researcher : Wong SSY

List of Research Outputs

Chan C.M., Tse H., Wong S.S.Y., Woo P.C.Y., Lau S.K.P., Chen L., Zheng B., Huang J. and Yuen K.Y., Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. , J Clin Virol. 2009, 45(1): 54-60.

Chan G.S.W., Tsoi H.W., Wong S.S.Y., Li C.L., Tse H., Uni K., Yuen K.Y. and Chan K.W., BK virus nephropathy due to KOM-3 strain., American journal of kidney diseases. 2008, 54(1): 122-126.

Ho P.L., Wong R.C., Chow K.H., Yip K., Wong S.S.Y. and Que T.L., CTX-M type beta-lactamases among fecal Escherichia coli and Klebsiella pneumoniae isolates in non-hospitalized children and adults., Journal of Microbiology, Immunology and Infection. 2008, 41: 428-32.

Lam C.W., Lan L.C.L., Che C.M., Tam S., Wong S.S.Y., Chen Y., Jin J., Tao S.H., Tang X.M., Yuen K.Y. and Tam P.K.H., Diagnosis and spectrum of melamine-related renal disease: plausible mechanism of stone formation in humans, Clinica Chimica Acta. 2009, 402: 150-155.

Wong S.S.Y. and Yuen K.Y., Antiviral therapy for respiratory tract infections., Respirology. 2008, 13(7): 950-971.

Wong S.S.Y. and Yuen K.Y., Avian influenza A/H5N1 virus: management in human and bird., Hong Kong Medical Journal. 2008, 14(4): 252-254.

Researcher : Woo PCY

List of Research Outputs

Chan C.M., Tse H., Wong S.S.Y., Woo P.C.Y., Lau S.K.P., Chen L., Zheng B., Huang J. and Yuen K.Y., Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. , J Clin Virol. 2009, 45(1): 54-60.

Chan C.M., Lau S.K.P., Woo P.C.Y., Tse H., Zheng B., Chen L., Huang J. and Yuen K.Y., Identification of Major Histocompatibility Antigen Class I C as an attachment coreceptor that facilitates Coronavirus HKU1 Spike-mediated infection, J Viral . 2009, 16(1): 45-52.

Chan C.M., Woo P.C.Y., Lau S.K.P., Tse H., Chen H., Li F., Zheng B., Chen L., Huang J. and Yuen K.Y., Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection, Exp Biol Med (Maywood). 2008, 33 (12): 1527-1536.

Lau S.K.P., Li K.S.M., Chau K.Y., So L.Y., Lee R.A., Lau Y.L., Chan K.H., Lim W.W.L., Woo P.C.Y. and Yuen K.Y., Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A, Journal of Clinical Microbiology. 2009, 47(5): 1549-1552.

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Woo P.C.Y., Lau S.K.P., Huang Y. and Yuen K.Y., Coronavirus diversity, phylogeny and interspecies jumping., Experimental biology and medicine (Maywood, N.J.). 2009, 234(10): 1117-1127.

Woo P.C.Y., Teng L.L., Tsang K.L., Tse H., Tsang V.Y.M., Chan K.M., Lee E.K.Y., Chan J.K.H., Tam D.M.W., Chung L.M.W., Lau S.K.P. and Yuen K.Y., Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea, BMC Microbiology. 2009, 9: 21.

Woo P.C.Y., Laribacter hongkongensis: from discovery to complete genome sequence, Second Ditan International Conference on Infectious Diseases (Beijing, China). 2008.

Woo P.C.Y., Lau S.K.P., Yip C.Y., Huang Y. and Yuen K.Y., More and More Coronaviruses: Human Coronavirus HKU1, Viruses. 2009, 1(1): 57-71.

Woo P.C.Y., More and more coronaviruses, 11th Western Pacific Congress on Chemotherapy and Infectious Diseases (Taipei, Taiwan). 2008.

Woo P.C.Y., More and more human and animal coronaviruses, Hong Kong Institute of Medical Laboratory Sciences Annual Scientific Meeting 2008 (Hong Kong). 2008.

Woo P.C.Y., More and more human and animal coronaviruses, Second Ditan International Conference on Infectious Diseases (Beijing, China). 2008.

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Woo P.C.Y., Teng L.L., Tsang S.N.Y., Tse C.W.S., Lau S.K.P. and Yuen K.Y., The oral cavity as a natural reservoir for Streptococcus sinensis, Clinical Microbiology And Infection. 2008, 14: 1075-1079.

Woo P.C.Y., Lau S.K.P., Teng L.L., Tse H. and Yuen K.Y., Then and now: use of 16S rDNA gene sequencing for bacterial identification and discovery of novel bacteria in clinical microbiology laboratories, Clinical Microbiology and Infection. 2008, 14: 908-34.

Woo P.C.Y., Unifying coronavirus phylogeny, Emerging infectious disease workshop (Taipei, Taiwan). 2008.

Researcher : Wu AKL

List of Research Outputs

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

Researcher : Wu WL

List of Research Outputs

Chen Y., Qin K., Wu W.L., Li G., Zhang J., Du H., Ng M.H., Shih W.K., Peiris J.S.M., Guan Y., Chen H. and Xia N., Broad Cross Protection Against H5N1 Avian Influenza Infection by Means of Monoclonal Antibodies that Map to conserved viral Epitopes, The Journal of Infectious Diseases. 2009, 199: 49-58.

Researcher : Yam WC

List of Research Outputs

Chen J.H.K., Wong K.H., Li P., Chan K.C.W., Lee M.P., Lam H.Y., Cheng V.C.C., Yuen K.Y. and Yam W.C., Molecular Epidemiological Study of HIV-1 CRF01_AE Transmission in Hong Kong , In: David D. Ho, MD, Paul A. Volberding, MD, William A. Blattner, MD, Journal of Acquired Immune Deficiency Syndromes. Wolters Kluwer, Lippincott Williams & Wilkins, 2009, 51: 530-535.

Cheng V.C.C., Yam W.C., Chan J.F.W., To K.K.W., Ho P.L. and Yuen K.Y., Clostridium difficile ribotype 027 arrives in Hong Kong., International Journal of Antimicrobial Agents. 2009, 54(5): 492-493.

Epstein C.R., Yam W.C., Peiris J.S.M. and Epstein R., Methicillin-resistant commensal staphylococci in healthy dogs as a potential zoonotic reservoir for community-acquired antibiotic resistance , Infection, Genetics and Evolution . 2009, 9(2): 283-5.

Lee S.S., Tam D.K., Tan Y., Mak W.L., Wong K.H., Chen J.H.K. and Yam W.C., An exploratory study on the social and genotypic clustering of HIV infection in men having sex with men, In: JA Levy, AIDS. Lippincott Williams & Wilkins, 2009, 23: 1755-1764.

Parahitiyawa N.B., Jin L.J., Leung W.K., Yam W.C. and Samaranayake L.P., Microbiology of odontogenic bacteremia: beyond endocarditis, Clinical Microbiology Reviews. 2009, 22(1): 46-64.

Sun H., Choy T.S.J., Zhu D., Yam W.C. and Fung Y.S., Nano-silver-modified Pqc/dna Biosensor For Detecting E. Coli In Environmental Water , Biosensors and Bioelectronics . 2009, 24: 1405-1410.

Zheng B., Zhao X., Lee S.S., Wong K.H., Chan K.C.W., Ng F., Yam W.C. and Yuen K.Y., Study of Polymorphisms in HIV-1 Co-receptors and Their Ligands in Chinese Population and Their Effects on HIV-1 Infection, XVII International AIDS Conference. Mexico City, Mexico, 2008.

Researcher : Yen H

List of Research Outputs

Yen H., Peiris J.S.M. and Peiris J.S.M., Mapping antibody epitopes of the avian H5N1 influenza virus, Public Library of Science (PLoS) Medicine. 2009, 6(4): e1000064.

Researcher : Yip CY

List of Research Outputs

Woo P.C.Y., Lau S.K.P., Yip C.Y., Huang Y. and Yuen K.Y., More and More Coronaviruses: Human Coronavirus HKU1, Viruses. 2009, 1(1): 57-71.

Researcher : Yip KS

List of Research Outputs

Ho P.L., Yip K.S., Chow K.H., Lo J.Y., Que T.L., Yuen K.Y. and Yuen K.Y., Antimicrobial resistance among uropathogens that cause acute uncomplicated cystitis in women in Hong Kong: a prospective multicenter study in 2006 to 2008., Diagnostic Microbiology and Infectious Disease. 2009.

Researcher : Yuen KY

List of Research Outputs

Chan C.M., Tse H., Wong S.S.Y., Woo P.C.Y., Lau S.K.P., Chen L., Zheng B., Huang J. and Yuen K.Y., Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. , J Clin Virol. 2009, 45(1): 54-60.

Chan C.M., Lau S.K.P., Woo P.C.Y., Tse H., Zheng B., Chen L., Huang J. and Yuen K.Y., Identification of Major Histocompatibility Antigen Class I C as an attachment coreceptor that facilitates Coronavirus HKU1 Spike-mediated infection, J Viral . 2009, 16(1): 45-52.

Chan C.M., Woo P.C.Y., Lau S.K.P., Tse H., Chen H., Li F., Zheng B., Chen L., Huang J. and Yuen K.Y., Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection, Exp Biol Med (Maywood). 2008, 33 (12): 1527-1536.

Chan G.S.W., Tsoi H.W., Wong S.S.Y., Li C.L., Tse H., Uni K., Yuen K.Y. and Chan K.W., BK virus nephropathy due to KOM-3 strain., American journal of kidney diseases. 2008, 54(1): 122-126.

Chan S., Chan S., Lam C., Leung A.Y.H., Leung D., Lam T.H., Johnston J., Chu D., Chan C.K., Hung I.F.N., Liang R.H.S. and Yuen K.Y., Evaluating a low intensity health education intervention on pneumococcal vaccination uptake among elders with chronic illneses., 20th National Conference on Chronic Disease Prevention and Control. Maryland, USA, 2009.

Chan S.S.C., Lam C.L.K., Leung A.Y.M., Leung Y.P., Lam T.H., Johnston J.M., Chu D.W.S., Chan C.K., Hung I.F.N., Liang R.H.S. and Yuen K.Y., Evaulating a low-intensity health education intervention on pneumococcal vaccination uptake among elders with chronic illinesses, 20th National Conference on Chronic Disease Prevention and Control: Cultivating Healthy Communities, Washington DC, USA. 23-25 February. 2009.

Chang K.C., Leung C.C., Yew W.W., Lam F.M., Ho P.L., Chau C.H., Cheng V.C.C. and Yuen K.Y., Analyses of fluoroquinolones and Clostridium difficile-associated diarrhoea in tuberculosis patients., The international journal of tuberculosis and lung disease. 2009, 13(3): 341-346.

Chen J.H.K., Wong K.H., Li P., Chan K.C.W., Lee M.P., Lam H.Y., Cheng V.C.C., Yuen K.Y. and Yam W.C., Molecular Epidemiological Study of HIV-1 CRF01_AE Transmission in Hong Kong , In: David D. Ho, MD, Paul A. Volberding, MD, William A. Blattner, MD, Journal of Acquired Immune Deficiency Syndromes. Wolters Kluwer, Lippincott Williams & Wilkins, 2009, 51: 530-535.

Cheng V.C.C., Yam W.C., Chan J.F.W., To K.K.W., Ho P.L. and Yuen K.Y., Clostridium difficile ribotype 027 arrives in Hong Kong., International Journal of Antimicrobial Agents. 2009, 54(5): 492-493.

Cheng V.C.C., Li W.S., Wu A.K.L., Tang S.F., Ng K.H., To K.K.W., Tse H., Que T.L., Ho P.L. and Yuen K.Y., Effect of antibiotics on the bacterial load of meticillin-resistant Staphylococcus aureus colonisation in anterior nares., Journal of Hospital Infection. 2008, 70: 23-34.

He M.L., Zheng B., Chen Y., Wong K.L., Huang J., Lin M.C., Yuen K.Y., Sung J.J. and Kung H.F., Development of Interfering RNA Agents to Inhibit SARS-associated Coronavirus Infection and Replication, Hong Kong Medical Journal. 2009, Suppl 4: S28-31.

Ho P.L., Yip K.S., Chow K.H., Lo J.Y., Que T.L., Yuen K.Y. and Yuen K.Y., Antimicrobial resistance among uropathogens that cause acute uncomplicated cystitis in women in Hong Kong: a prospective multicenter study in 2006 to 2008., Diagnostic Microbiology and Infectious Disease. 2009.

Lam C.W., Lan L.C.L., Che C.M., Tam S., Wong S.S.Y., Chen Y., Jin J., Tao S.H., Tang X.M., Yuen K.Y. and Tam P.K.H., Diagnosis and spectrum of melamine-related renal disease: plausible mechanism of stone formation in humans, Clinica Chimica Acta. 2009, 402: 150-155.

Lau S.K.P., Li K.S.M., Chau K.Y., So L.Y., Lee R.A., Lau Y.L., Chan K.H., Lim W.W.L., Woo P.C.Y. and Yuen K.Y., Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A, Journal of Clinical Microbiology. 2009, 47(5): 1549-1552.

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Li Z., He M.L., Yao H., Dong Q.M., Chen Y.C., Chan C.Y., Zheng B., Yuen K.Y., Peng Y., Sun Q., Yang X., Lin M.C., Sung J.J. and Kung H.F., Inhibition of HBV Replication and Gene Expression in vitro and in vivo with a Single AAV Vector Delivering Two shRNA Molecules, BMB Reports. 2009, 42(1): 59-64.

Poon L.L.M., Chan K.H., Leung C.S.W., Smith G.J., Guan Y., Yuen K.Y. and Peiris J.S.M., Molecular Detection of a Novel Human Influenza (H1N1) of Pandemic Potential by Conventional and Real-Time Quantitative RT-PCR Assays, Clinical Chemistry. 2009, 55: 1555-1558.

Siu K.L., Kok K.H., Ng M.H., Poon K.M., Yuen K.Y., Zheng B. and Jin D., Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex., Journal of Biological Chemistry. 2009, 284: 16202-16209.

Sui H., Zhao G., Huang J., Jin D., Yuen K.Y. and Zheng B., Small Interfering RNA Targeting M2 Gene Induces Effective and Long term Inhibition of Influenza A Virus Replication. , PloS One. 2009, 4(5): e5671.

Tang H.W., Ng K.M., Chui S.Y., Che C.M., Lam C.W., Yuen K.Y., Siu T.S., Lan L.C.L. and Chen X.Y., Analysis of Melamine Cyanurate in Urine Using Matrix-Assisted Laser Desorption / Ionization Mass Spectrometry , Analytical Chemistry. 2009, 81: 3676-3682.

Wang W., Wei L., Yang A., He T., Yuen K.Y., Chen C. and Rao Z., Expression, crystallization and preliminary crystallographic study of human coronavirus HKU1 nonstructural protein 9., Acta crystallographica. Section F, Structural biology and crystallization communications. 2009, 65(Pt 5): 526-528.

Wong S.S.Y. and Yuen K.Y., Antiviral therapy for respiratory tract infections., Respirology. 2008, 13(7): 950-971.

Wong S.S.Y. and Yuen K.Y., Avian influenza A/H5N1 virus: management in human and bird., Hong Kong Medical Journal. 2008, 14(4): 252-254.

Wong S.Y.A., Cheng V.C.C., Yuen K.Y., Kwong Y.L. and Leung A.Y.H., High frequency of polyoma BK virus shedding in the gastrointestinal tract after hematopoietic stem cell transplantation: a prospective and quantitative analysis, Bone Marrow Transplantation. Epub, 2008, 43: 43–47.

Woo P.C.Y., Lau S.K.P., Huang Y. and Yuen K.Y., Coronavirus diversity, phylogeny and interspecies jumping., Experimental biology and medicine (Maywood, N.J.). 2009, 234(10): 1117-1127.

Woo P.C.Y., Teng L.L., Tsang K.L., Tse H., Tsang V.Y.M., Chan K.M., Lee E.K.Y., Chan J.K.H., Tam D.M.W., Chung L.M.W., Lau S.K.P. and Yuen K.Y., Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea, BMC Microbiology. 2009, 9: 21.

Woo P.C.Y., Lau S.K.P., Yip C.Y., Huang Y. and Yuen K.Y., More and More Coronaviruses: Human Coronavirus HKU1, Viruses. 2009, 1(1): 57-71.

Woo P.C.Y., Lau S.K.P., Tse H., Teng L.L., Curreem O.T.S., Tsang K.L., Fan Y.Y., Wong K.M.G., Huang Y., Loman N.J., Snyder L.A., Cai J., Huang J., Mak W.W., Pallen M.J., Lok S. and Yuen K.Y., The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats, PLoS Genetics. 2009, 5: e1000416.

Woo P.C.Y., Teng L.L., Tsang S.N.Y., Tse C.W.S., Lau S.K.P. and Yuen K.Y., The oral cavity as a natural reservoir for Streptococcus sinensis, Clinical Microbiology And Infection. 2008, 14: 1075-1079.

Woo P.C.Y., Lau S.K.P., Teng L.L., Tse H. and Yuen K.Y., Then and now: use of 16S rDNA gene sequencing for bacterial identification and discovery of novel bacteria in clinical microbiology laboratories, Clinical Microbiology and Infection. 2008, 14: 908-34.

Yu B., Yuen K.Y., Zheng B. and Huang J., Development of Salmonella-mediated Oral Vaccine against Avian Influenza Viruses H5N1, 13th Research Postgraduate Symposium, HKU. Hong Kong December 10 & 11. 2008.

Zeng Y., Zhou J., Chen D., Poon K.M., Ng F., Yuen K.Y. and Zheng B., A SNP in IFNGR1 promoter is correlated to the susceptibility to chronic HBV infection in Chinese population, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zhang Z., Zhang J., Huang K., Li K.S., Yuen K.Y., Guan Y., Chen H. and Ng W.F., Systemic infection of avian influenza A virus H5N1 subtype in human, Human Pathology. 2009, 40: 735-739.

Zheng B., Zhou J., Huang J., Lu L. and Yuen K.Y., An IFN-a/b receptor 1 promoter variant and hepatitis B virus synergistically increase the susceptibility to chronic hepatitis B, 2008 International Meeting: The Molecular Biology of Hepatitis B Viruses. San Diego, California, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., He Y., Jiang S., Wu C., Jin D., Zhou Y. and Yuen K.Y., SARS-CoV S Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection. , Vaccine 2nd Congress. Boston, MA, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Zheng B., Zhao X., Lee S.S., Wong K.H., Chan K.C.W., Ng F., Yam W.C. and Yuen K.Y., Study of Polymorphisms in HIV-1 Co-receptors and Their Ligands in Chinese Population and Their Effects on HIV-1 Infection, XVII International AIDS Conference. Mexico City, Mexico, 2008.

Zhou J., Chen D., Poon K.M., Zeng Y., Ng F., Lu L., Huang J., Yuen K.Y. and Zheng B., A comprehensive study of interferon-γ receptor 1 gene polymorphisms and susceptibility to chronic hepatitis B virus infection. , Immunogenetics. 2009, 61(6): 423-430.

Zhou J., Smith D.K., Lu L., Poon K.M., Ng F., Chen D., Huang J., Yuen K.Y. and Zheng B., A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection, J Viral Hepat. 2009, 16(1): 45-52.

Zhou J., Huang J., Poon V.K.M., Chen D.Q., Chan C.C.S., Ng F., Guan X.Y., Watt R.M., Lu L., Yuen K.Y. and Zheng B., Functional dissection of an IFN-α/β receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection , Journal of Hepatology. 2009, V51(2): 322-32.

Researcher : Yung RWH

List of Research Outputs

Cowling B.J., Leung G.M., Peiris J.S.M., Chan K.H., Yung R.W.H. and Seto W.H., A controlled trial of masks and hand hygiene for reducting influenza transmission, The University of Hong Kong (abstract), CDC Nonpharmaceutical Interventions for Pandemic Influenza PI Meeting, 4-6 March 2009, Atlanta. Atlanta, Centres for Disease Control and Prevention, 2009, 19-20.

Cowling B.J., Chan K.H., Fang J., Cheng K.Y., Fung R.O.P., Lim Wai W.S., Sin J.W.F., Seto W.H., Yung R.W.H., Chu D.W.S., Chiu B.C.F., Lee P.W.Y., Chiu M.C., Lee H.C., Uyeki T.M., Houck P.M., Peiris J.S.M. and Leung G.M., Findings of a cluster randomized controlled trial of face masks and hand hygiene to prevent influenza transmission in households (abstract and oral presentation), XI International Symposium on Respiratory Viral Infections, 19-22 February 2009, Bangkok, Thailand. Bangkok, Thailand, The Macrae Group LLC, 2009, I-2.

Researcher : Zeng Y

List of Research Outputs

Zeng Y., Zhou J., Chen D., Poon K.M., Ng F., Yuen K.Y. and Zheng B., A SNP in IFNGR1 promoter is correlated to the susceptibility to chronic HBV infection in Chinese population, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zeng Y., Chan K.C.W., Chan C.S., Ng F., Wong K.H. and Zheng B., Detection of HIV specific cytotoxic T lymphocytes viral delivery system, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zhou J., Chen D., Poon K.M., Zeng Y., Ng F., Lu L., Huang J., Yuen K.Y. and Zheng B., A comprehensive study of interferon-γ receptor 1 gene polymorphisms and susceptibility to chronic hepatitis B virus infection. , Immunogenetics. 2009, 61(6): 423-430.

Researcher : Zhang H

List of Research Outputs

Wang Y., Zhang H., Xu J., Zheng B. and Wen Y., Mutational Analysis Of The "turn" Of Helix Clamp Motif Of Hiv-1 Reverse Transcriptase, Biochem Biophys Res Commun.. elsevier, 2008, 377: 915-920.

Wang Y.X., Zhang H., Xu J., Zheng B. and Wen Y.M., Mutational analysis of the “turn” of helix clamp motif of HIV-1 reverse transcriptase, Biochem. Biophys. Res. Commun. 2008, 377(3): 915-920.

Researcher : Zhang H

List of Research Outputs

Wang Y., Zhang H., Xu J., Zheng B. and Wen Y., Mutational Analysis Of The "turn" Of Helix Clamp Motif Of Hiv-1 Reverse Transcriptase, Biochem Biophys Res Commun.. elsevier, 2008, 377: 915-920.

Researcher : Zhang J

List of Research Outputs

Carrington C.V.F., Foster J.E., Zhu H., Zhang J., Smith G.J., Thompson N., Auguste A.J., Ramkissoon V., Adesiyun A.A. and Guan Y., Detection and phylogenetic analysis of group 1 coronaviruses in South American bats., Emerg Infect Dis.. 2008, 14: 1890-1893.

Dhanasekaran V., Bahl J., Riley S., Duan L., Zhang J., Chen H., Peiris J.S.M., Smith G.J. and Guan Y., Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses, PLoS Pathogens. 2008, 26: e1000161.

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Zhang Z., Zhang J., Huang K., Li K.S., Yuen K.Y., Guan Y., Chen H. and Ng W.F., Systemic infection of avian influenza A virus H5N1 subtype in human, Human Pathology. 2009, 40: 735-739.

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

Researcher : Zhang L

List of Research Outputs

Duan L., Bahl J., Smith G.J., Wang J., Dhanasekaran V., Zhang L., Zhang J., Li K.S., Fan X.H., Cheung C.L., Huang K., Poon L.L.M., Shortridge K.F., Webster R.G., Peiris J.S.M., Chen H. and Guan Y., The development and genetic diversity of H5N1 influenza virus in China, 1996-2006, Virology. 2008, 380: 243-254.

Smith G.J., Dhanasekaran V., Ellis T.M., Dyrting K.C., Leung C.Y.H., Bahl J., Wong C.W., Huang K., Chow M.K.W., Duan L., Chan A.S.L., Zhang L., Chen H., Luk G.S.M., Peiris J.S.M. and Guan Y., Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008, Emerging Infectious Diseases. 2009, 15: 402-407.

Researcher : Zhang Q

List of Research Outputs

Li H., Zhou R., Chen J., Tian X., Zhang Q., Zeng Q. and Gong S., A recombinant replication-defective human adenovirus type 3: A vaccine candidate, Vaccine. 2009, 27(1): 116-122.

Zhang Q., Su X., Seto D., Zheng B., Tian X., Sheng H., Li H., Wang Y. and Zhou R., Construction and characterization of a replication-competent human adenovirus type 3-based vector for use as a live-vaccine candidate, and as a gene therapy vector. , Vaccine. 2009, 27(8): 1145-1153.

Zhao D., Peng D., Zhang Q. and Zhang C., Inhibition of G1P3 expression found in the differential display study on respiratory syncytial virus infection, Virol J. 2008, 5: 114-120.

Researcher : Zhao G

List of Research Outputs

Sui H., Zhao G., Huang J., Jin D., Yuen K.Y. and Zheng B., Small Interfering RNA Targeting M2 Gene Induces Effective and Long term Inhibition of Influenza A Virus Replication. , PloS One. 2009, 4(5): e5671.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., He Y., Jiang S., Wu C., Jin D., Zhou Y. and Yuen K.Y., SARS-CoV S Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection. , Vaccine 2nd Congress. Boston, MA, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Researcher : Zhao P

List of Research Outputs

Wang P., Song W., Mok B.W.Y., Zhao P., Qin K., Lai A.C.K., Smith G.J., Zhang J., Lin T., Guan Y. and Chen H., Nuclear factor 90, NF90, negatively regulates influenza virus replication by interacting with viral nucleoprotein, Journal of Virology. 2009, 83: 7850-61.

Researcher : Zhao X

List of Research Outputs

Zheng B., Zhao X., Lee S.S., Wong K.H., Chan K.C.W., Ng F., Yam W.C. and Yuen K.Y., Study of Polymorphisms in HIV-1 Co-receptors and Their Ligands in Chinese Population and Their Effects on HIV-1 Infection, XVII International AIDS Conference. Mexico City, Mexico, 2008.

Researcher : Zheng B

List of Research Outputs

Bian C., Zhang X., Cai X., Zhang L., Chen Z., Zha Y., Xu Y., Xu K., Lu W., Yan L., Yuan J., Feng J., Hao P., Wang Q., Zhao G., Liu G., Zhu X., Shen H., Zheng B. and Shen B., Conserved amino acids W423 and N424 in receptor-binding domain of SARS-CoV are potential targets for therapeutic monoclonal antibody, Virology. 2009, 383 (1): 39-46.

Chan C.M., Tse H., Wong S.S.Y., Woo P.C.Y., Lau S.K.P., Chen L., Zheng B., Huang J. and Yuen K.Y., Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. , J Clin Virol. 2009, 45(1): 54-60.

Chan C.M., Lau S.K.P., Woo P.C.Y., Tse H., Zheng B., Chen L., Huang J. and Yuen K.Y., Identification of Major Histocompatibility Antigen Class I C as an attachment coreceptor that facilitates Coronavirus HKU1 Spike-mediated infection, J Viral . 2009, 16(1): 45-52.

Chan C.M., Woo P.C.Y., Lau S.K.P., Tse H., Chen H., Li F., Zheng B., Chen L., Huang J. and Yuen K.Y., Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection, Exp Biol Med (Maywood). 2008, 33 (12): 1527-1536.

Chen J.Y., Chen W.N., Poon K.M., Zheng B., Lin X., Wang Y.X. and Wen Y.M., Interaction between SARS-CoV helicase and a multifunctional cellular protein (Ddx5) revealed by yeast and mammalian cell two-hybrid systems. , Archives of Virology. 2009, 154(3): 507-512.

Chen L., Hu L., Chan H.M., Tsao G.S.W., Huo K.K., Fu L., Ma S.K.Y., Zheng B. and Guan X.Y., Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival., Hepatology. 2009, 50: 122-129.

Du L., He Y., Zhou Y., Liu S., Zheng B. and Jiang S., The spike protein of SARS-CoV — a target for vaccine and therapeutic development. , Nat Rev Micro. 2009, 7(3):: 226-236.

He M.L., Zheng B., Chen Y., Wong K.L., Huang J., Lin M.C., Yuen K.Y., Sung J.J. and Kung H.F., Development of Interfering RNA Agents to Inhibit SARS-associated Coronavirus Infection and Replication, Hong Kong Medical Journal. 2009, Suppl 4: S28-31.

Huang J., Zheng B. and Sun H., Helicases as antiviral drug targets., Hong Kong Med J. 2008, 14(4, Suppl 4): 36-38.

Kung H., He M.L., Zheng B., Guan Y., Lin M.C. and Peng Y., Inhibition of SARS-Associated Coronavirus (SCoV) Infection and Replication by RNA Interference, U.S. Patent No. 7,429,656. 2008.

Lam Q.L.K., Ko K.H., Zheng B. and Lu L., Local BAFF gene silencing suppresses Th17-cell generation and ameliorates autoimmune arthritis, Proc Natl Acad Sci USA. 2008, 105(39): 14993-14998.

Lau S.K.P., Woo P.C.Y., Tse H., Fu C.T.-.Y., Au W.K., Chen X.C., Tsoi H.W., Tsang T.H.F., Chan J.S.Y., Tsang D.N.C., Li S.M.K., Tse C.W.S., Ng T.K., Tsang O.T.Y., Zheng B., Tam S.C.T., Chan K.H., Zhou P. and Yuen K.Y., Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4, J Gen Virol. 2008, 89(8): 1840-1848.

Li Z., He M.L., Yao H., Dong Q.M., Chen Y.C., Chan C.Y., Zheng B., Yuen K.Y., Peng Y., Sun Q., Yang X., Lin M.C., Sung J.J. and Kung H.F., Inhibition of HBV Replication and Gene Expression in vitro and in vivo with a Single AAV Vector Delivering Two shRNA Molecules, BMB Reports. 2009, 42(1): 59-64.

Lin Y., Shum K.T., Tanner J.A. and Zheng B., In vitro selection of DNA aptamers binding H5N1 Virus nucleoprotein, HKU 13th Research Postgraduate Symposium. 2008.

Lo C.K., Lam Q.L.K., Sun L., Wang S., Ko K.H., Xu H., Wu C.Y., Zheng B. and Lu L., Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production, Arthritis and Rheumatism. 2008, 58(9): 2700-2711.

Lu C.Y., Lu J.H., Chen W.Q., Jiang L.F., Tan B.Y., Ling W.H., Zheng B. and Sui H., Potential infections of H5N1 and H9N2 avian influenza do exist in Guangdong populations of China, Chinese Medical Journal. 2008, 121(20): 2050-2053.

Ma S.K.Y., Chan K.W., Lee K.W., Tang K.H., Wo Y.H., Zheng B. and Guan X.Y., Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations, Molecular Cancer Research. 2008, 6: 1146-1153.

Ma S.K.Y., Chan Y.P., Lee K.W., Tang K.H., Ng I.O.L., Man K., To K.F., Zheng B., Chan K.W. and Guan X.Y., The role of miR-130b in the regulation of CD133+ cancer stem cells-driven hepatocellular carcinoma, The 100th Annual Meeting of the American Association for Cancer Research, Denver, Colorado, U.S.A., 18-22 April 2009.

Siu K.L., Kok K.H., Ng M.H., Poon K.M., Yuen K.Y., Zheng B. and Jin D., Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex., Journal of Biological Chemistry. 2009, 284: 16202-16209.

Sui H., Zhao G., Huang J., Jin D., Yuen K.Y. and Zheng B., Small Interfering RNA Targeting M2 Gene Induces Effective and Long term Inhibition of Influenza A Virus Replication. , PloS One. 2009, 4(5): e5671.

Tang K.H., Ma S.K.Y., Lee K.W., Ng I.O.L., Man K., To K.F., Zheng B., Guan X.Y. and Chan K.W., CD133+ liver cancer stem cells promote tumor growth and angiogenesis through increased interleukin-8 secretion, The 100th Annual Meeting of the American Association for Cancer Research, Denver, Colorado, U.S.A., 18-22 April 2009.

Wang M., Fu C.X. and Zheng B., Antibodies against H5 and H9 Avian Influenza among Poultry Workers in China. , New Engl J Med. 2009, 360(24): 2583-2584.

Wang Y., Zhang H., Xu J., Zheng B. and Wen Y., Mutational Analysis Of The "turn" Of Helix Clamp Motif Of Hiv-1 Reverse Transcriptase, Biochem Biophys Res Commun.. elsevier, 2008, 377: 915-920.

Wang Y.X., Zhang H., Xu J., Zheng B. and Wen Y.M., Mutational analysis of the “turn” of helix clamp motif of HIV-1 reverse transcriptase, Biochem. Biophys. Res. Commun. 2008, 377(3): 915-920.

Xu K., Zheng B., Zeng R., Lu W., Lin Y., Xue L., Li L., Yang L.L., Xu C., Dai J., Wang F., Li Q., Dong Q.X., Yang R.F., Wu J.R. and Sun B., Severe Acute Respiratory Syndrome Coronavirus Accessory Protein 9b Is a Virion-Associated Protein. , Virology . 2009, 388(2): 279-85.

Yu B., Yuen K.Y., Zheng B. and Huang J., Development of Salmonella-mediated Oral Vaccine against Avian Influenza Viruses H5N1, 13th Research Postgraduate Symposium, HKU. Hong Kong December 10 & 11. 2008.

Zeng Y., Zhou J., Chen D., Poon K.M., Ng F., Yuen K.Y. and Zheng B., A SNP in IFNGR1 promoter is correlated to the susceptibility to chronic HBV infection in Chinese population, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zeng Y., Chan K.C.W., Chan C.S., Ng F., Wong K.H. and Zheng B., Detection of HIV specific cytotoxic T lymphocytes viral delivery system, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zhang Q., Su X., Seto D., Zheng B., Tian X., Sheng H., Li H., Wang Y. and Zhou R., Construction and characterization of a replication-competent human adenovirus type 3-based vector for use as a live-vaccine candidate, and as a gene therapy vector. , Vaccine. 2009, 27(8): 1145-1153.

Zheng B., Zhou J., Huang J., Lu L. and Yuen K.Y., An IFN-a/b receptor 1 promoter variant and hepatitis B virus synergistically increase the susceptibility to chronic hepatitis B, 2008 International Meeting: The Molecular Biology of Hepatitis B Viruses. San Diego, California, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., He Y., Jiang S., Wu C., Jin D., Zhou Y. and Yuen K.Y., SARS-CoV S Protein Induces Strong Mucosal Immune Responses and Provides Long-term Protection Against SARS-CoV Infection. , Vaccine 2nd Congress. Boston, MA, USA, 2008.

Zheng B., Du L., Zhao G., Lin Y., Sui H., Chan C.S., Ma S., Guan Y. and Yuen K.Y., Studies of SARS virus vaccines, Hong Kong Med J. 2008, 14(4, Suppl 4): 39-43.

Zheng B., Zhao X., Lee S.S., Wong K.H., Chan K.C.W., Ng F., Yam W.C. and Yuen K.Y., Study of Polymorphisms in HIV-1 Co-receptors and Their Ligands in Chinese Population and Their Effects on HIV-1 Infection, XVII International AIDS Conference. Mexico City, Mexico, 2008.

Zheng B., Guan Y., Huang J. and He M.L., Synthetic Peptide Targeting Critical Sites on the SARS-Associated Coronaviurs Spike Protein Responsible for Viral Infection and a Method of Use Thereof, U.S. Patent No. 7,491,489. 2009.

Zhou J., Chen D., Poon K.M., Zeng Y., Ng F., Lu L., Huang J., Yuen K.Y. and Zheng B., A comprehensive study of interferon-γ receptor 1 gene polymorphisms and susceptibility to chronic hepatitis B virus infection. , Immunogenetics. 2009, 61(6): 423-430.

Zhou J., Smith D.K., Lu L., Poon K.M., Ng F., Chen D., Huang J., Yuen K.Y. and Zheng B., A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection, J Viral Hepat. 2009, 16(1): 45-52.

Zhou J., Huang J., Poon V.K.M., Chen D.Q., Chan C.C.S., Ng F., Guan X.Y., Watt R.M., Lu L., Yuen K.Y. and Zheng B., Functional dissection of an IFN-α/β receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection , Journal of Hepatology. 2009, V51(2): 322-32.

Researcher : Zhou J

List of Research Outputs

Zeng Y., Zhou J., Chen D., Poon K.M., Ng F., Yuen K.Y. and Zheng B., A SNP in IFNGR1 promoter is correlated to the susceptibility to chronic HBV infection in Chinese population, The 19th European Congress of Clinical Microbiology and Infectious Diseases. Helsinki, Finland, 2009.

Zheng B., Zhou J., Huang J., Lu L. and Yuen K.Y., An IFN-a/b receptor 1 promoter variant and hepatitis B virus synergistically increase the susceptibility to chronic hepatitis B, 2008 International Meeting: The Molecular Biology of Hepatitis B Viruses. San Diego, California, USA, 2008.

Zhou J., Chen D., Poon K.M., Zeng Y., Ng F., Lu L., Huang J., Yuen K.Y. and Zheng B., A comprehensive study of interferon-γ receptor 1 gene polymorphisms and susceptibility to chronic hepatitis B virus infection. , Immunogenetics. 2009, 61(6): 423-430.

Zhou J., Smith D.K., Lu L., Poon K.M., Ng F., Chen D., Huang J., Yuen K.Y. and Zheng B., A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection, J Viral Hepat. 2009, 16(1): 45-52.

Zhou J., Huang J., Poon V.K.M., Chen D.Q., Chan C.C.S., Ng F., Guan X.Y., Watt R.M., Lu L., Yuen K.Y. and Zheng B., Functional dissection of an IFN-α/β receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection , Journal of Hepatology. 2009, V51(2): 322-32.

Researcher : Zhu H

List of Research Outputs

Carrington C.V.F., Foster J.E., Zhu H., Zhang J., Smith G.J., Thompson N., Auguste A.J., Ramkissoon V., Adesiyun A.A. and Guan Y., Detection and phylogenetic analysis of group 1 coronaviruses in South American bats., Emerg Infect Dis.. 2008, 14: 1890-1893.

Zhu H., Chu D.K.W., Liu W., Dong B.Q., Zhang S.Y., Zhang J., Li L., Dhanasekaran V., Smith G.J., Chen H., Poon L.L.M., Peiris J.S.M. and Guan Y., Detection of diverse astroviruses from bats in China, Journal of General Virology. 2009, 90: 883-887.

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