DENTAL FACULTY - PERIODONTOLOGY
| Researcher : Cheng T |
| Project Title: | Crosstalk of Porphyromonas gingivalis and Helicobacter pylori with human gastric and gingival epithelial cells in molecular signaling |
| Investigator(s): | Cheng T, Jin L, Sun H |
| Department: | Dental Faculty - Periodontology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2015 |
| Completion Date: | 08/2016 |
| Project Title: | Doris Zimmern HKU-Cambridge Hughes Hall Fellowships 2015-16 |
| Investigator(s): | Cheng T |
| Department: | Dental Faculty - Periodontology |
| Source(s) of Funding: | Doris Zimmern HKU-Cambridge Hughes Hall Fellowships |
| Start Date: | 09/2015 |
| List of Research Outputs |
| Cheng T., Sun H. and Jin L., Bismuth inhibits Porphyromonas gingivalis through replacing ferrous ion in hemin, Journal of Dental Research. 2015, 94 (Spec Iss B): 109 (SEA Division). |
| Cheng T., Li H., Xia W., Jin L. and Sun H., Exploration into the nickel ‘microcosmos’ in prokaryotes, Coordination Chemistry Reviews. 2016, 311: 24-37. |
| Cheng T., Sun H., Lai Y.T., YANG Y. and Jin L., Fluorescence- and 2D gel-based bismuth-proteome of Porphyromonas gingivalis, Journal of Dental Research. 2016, 95 (Spec Iss B): 95. |
| Researcher : Corbet EF |
| Project Title: | Effects of periodontal therapy on the control of hypertension |
| Investigator(s): | Corbet EF, Lai SML |
| Department: | Dental Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2009 |
| List of Research Outputs |
| Leung S.C.Y., Ho K.L., Leung W.K. and Corbet E.F., Application of minimally invasive non-surgical periodontal therapy in periodontal treatment, Journal of Dental Research. 2015, 94 (Spec Iss B): 235 (SEA Division). |
| Leung W.K., Duan Y.R., Dong X.X., Yeung S.K.W., Zhou S.Y., Corbet E.F. and Meng H.X., Perception of Non-surgical Periodontal Treatment in Individuals Receiving or Not Receiving Local Ananesthesia, Oral Health & Preventive Dentistry. 2016, 14(2): 165-175. |
| Tse I.Y.K., Ho K.L., Leung W.K. and Corbet E.F., Application of air polishing in treatment of peri-implant mucositis, Journal of Dental Research. 2015, 94 (Spec Iss B): 155 (SEA Division). |
| Researcher : Ho KL |
| Project Title: | Applications of Photodynamic Therapy on management of Drug Influenced Gingival Enlargement: A Preliminary Double-blinded Randomized Clinical Controlled Trial. |
| Investigator(s): | Ho KL, Leung WK, Chan DTM |
| Department: | Dental Faculty - Periodontology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2015 |
| List of Research Outputs |
| Ho K.L., Editorial Board Member, Austin Journal of Dentistry. 2016. |
| Ho K.L., Chu C.H., Cheung M.T.L. and Duangthip D., Faculty Knowledge Exchange (KE) Award 2016 “Empowering a Non-governmental non-profit organization to deliver primary oral care to Hong Kong Citizens”, The University of Hong Kong. 2016. |
| Ho K.L., Professional Discipline Workshop, Faculty of Dentistry, The University of Hong Kong. 2016. |
| Ho K.L., Quality Assurance and Ethics, The College of Dental Surgeons of Hong Kong & Hong Kong Dental Association - Membership in General Dentistry (MGD) Training Program. 2016. |
| Ho K.L., Revision of Crown Lengthening Surgery, Malaysian Society of Periodontology 7th Biennial Scientific Meeting. 2016. |
| Leung S.C.Y., Ho K.L., Leung W.K. and Corbet E.F., Application of minimally invasive non-surgical periodontal therapy in periodontal treatment, Journal of Dental Research. 2015, 94 (Spec Iss B): 235 (SEA Division). |
| Tse I.Y.K., Ho K.L., Leung W.K. and Corbet E.F., Application of air polishing in treatment of peri-implant mucositis, Journal of Dental Research. 2015, 94 (Spec Iss B): 155 (SEA Division). |
| Researcher : Jin L |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Jin L |
| Department: | Dental Faculty |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 12/2010 |
| Project Title: | Mechanism of Antifungal Resistance in Candida Persisters: Roadmap to Unravel Biofilm Resistance? |
| Investigator(s): | Jin L, Che CM, Seneviratne CJ, Samaranayake LP |
| Department: | Dental Faculty - Periodontology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 10/2012 |
| Completion Date: | 06/2016 |
| Project Title: | Novel antifungal small molecule for multi-drug resistant Candida: anti-biofilm activity, in vivo efficacy and cellular targets |
| Investigator(s): | Jin L, Kao RYT, Wang Y, Seneviratne CJ, Samaranayake LP |
| Department: | Dental Faculty - Periodontology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 10/2012 |
| Completion Date: | 10/2016 |
| Project Title: | Nano-encapsulated Chinese herbal extracts as novel immunomodulators and enhancers of innate host defense in human gingiva |
| Investigator(s): | Jin L, Seneviratne CJ |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2012 |
| Completion Date: | 11/2015 |
| Project Title: | Crosstalk of human gingival/oral epithelial cells and monocytes with P. gingivalis/P. gingivalis DNA: Epigenetic regulation and molecular signaling |
| Investigator(s): | Jin L, Seneviratne CJ |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| List of Research Outputs |
| AB MALIK N.B., Lam O.L.T., ZHANG J., Jin L. and McGrath C.P.J., Effectivess of computer-aided learning in oral health among patients and caregivers - A systematic review, Journal of Dental Research. 2015, 94 (Spec Iss B): 033 (SEA Division). |
| ACHARYA A., Koh M.L., Kheur S., Watt R.M., Jin L. and Mattheos N., Salivary IL-1β and red complex bacteria as predictors of the inflammatory status in sub-peri-implant niches of subjects with peri-implant mucositis, Clinical Oral Implants Research. 2016, 27: 662-667. |
| ACHARYA A., Kheur S., Gopalakrishnan D., Watt R.M., Jin L. and Mattheos N., Salivary interleukin-1b response is associated with microbiome diversity, Journal of Dental Research. 2016, 95 (Spec Iss B): 1247. |
| Cheng C.K., Jin L. and Pelekos G., Halitosis and oral/periodontal conditions in Hong Kong adults, Journal of Dental Research. 2015, 94 (Spec Iss B): 240 (SEA Division). |
| Cheng T., Sun H. and Jin L., Bismuth inhibits Porphyromonas gingivalis through replacing ferrous ion in hemin, Journal of Dental Research. 2015, 94 (Spec Iss B): 109 (SEA Division). |
| Cheng T., Li H., Xia W., Jin L. and Sun H., Exploration into the nickel ‘microcosmos’ in prokaryotes, Coordination Chemistry Reviews. 2016, 311: 24-37. |
| Cheng T., Sun H., Lai Y.T., YANG Y. and Jin L., Fluorescence- and 2D gel-based bismuth-proteome of Porphyromonas gingivalis, Journal of Dental Research. 2016, 95 (Spec Iss B): 95. |
| Dissanayaka W.L., ZHU L., Hargreaves K.M., Jin L. and Zhang C., 2016 IADR/AADR William J. Gies Award for Biomaterials and Bioengineering Research, IADR/AADR. 2016. |
| Dissanayaka W.L., ZHU L., Hargreaves K.M., Jin L. and Zhang C., 2016 Journal of Endodontics Awards, the best articles published in JOE during the 2015 calendar year, 2016. |
| JIANG S., Gao X., Jin L. and Lo E.C.M., Best poster award, Salivary Research Group, International Association for Dental Research. 2016. |
| JIANG S., Gao X., Jin L. and Lo E.C.M., Salivary microbiome diversity in caries-free and caries-affected children, Journal of Dental Research. 2016, 95 (Spec Iss B): 1241. |
| Jin L., P. gingivalis as a keystone periodontal pathogen: A challenging note, Journal of Dental Research. 2016, 95 (Spec Iss B): 839. |
| LI P., Fung E.Y.M., Seneviratne C., Che C.M. and Jin L., Controlled redox and hemin utilization essential for Porphyromonas gingivalis persistence, Journal of Dental Research. 2016, 95 (Spec Iss B): 892. |
| LI P., Seneviratne C.J., Emanuele A., Vizacino J.A. and Jin L., Delicate metabolic control and coordinated stress response critically determine antifungal tolerance of Candida albicans biofilm persisters, Antimicrobial Agents and Chemotherapy. 2015, 59: 6101-6112. |
| LI P., Seneviratne C.J., WANG Y. and Jin L., Hemin-dependent regulation in persistence of Porphyromonas gingivalis, Journal of Dental Research. 2015, 94 (Spec Iss B): 013. |
| LI X., Pang K.Y., Leung K.C.F. and Jin L., Cellular internalization and epithelial penetration of fluorescent-labeled mesoporous silica nanoparticles, Journal of Dental Research. 2016, 95 (Spec Iss B): 2022. |
| LI X., Wong C.H., Ng T.W., Zhang C., Leung K.C.F. and Jin L., The spherical nanoparticle-encapsulated chlorhexidine enhances anti-biofilm efficiency through an effective releasing mode and close microbial interactions, International Journal of Nanomedicine. 2016, 2471-2480. |
| Leung K.C.F., Seneviratne C.J., LI X., Leung P.C., Lau C.B.S., Wong C.H., Pang K.Y., Wong C.W., Wat E. and Jin L., Synergistic Antibacterial Effects of Nanoparticles Encapsulated with Scutellaria baicalensis and Pure Chlorhexidine on Oral Bacterial Biofilms, Nanomaterials. 2016, 6: 61. |
| REN C., McGrath C.P.J., Jin L., Zhang C. and Yang Y., The effectiveness of low-level laser therapy as an adjunct to non-surgical periodontal treatment: a meta-analysis., J Periodontal Res. 2016. |
| Seneviratne C.J., Rajan S., Wong S.S.W., Tsang D.N.C., Lai C.K.C., Samaranayake L.P. and Jin L., Antifungal Susceptibility in Serum and Virulence Determinants of Candida Bloodstream Isolates from Hong Kong, Frontiers in Microbiology. 2016, 7: 216. |
| WANG S., LIU K., SENEVIRATNE J.S., Li X.C., Cheung G.S.P., Jin L., Chu C.H. and Zhang C., Lipoteichoic acid from an Enterococcus faecalis clinical strain promotes TNF-α expression through the NF-κB and p38 MAPK signaling pathways in differentiated THP-1 macrophages, Biomedical Reports. 2015, 3: 697-702. |
| WANG S., Deng Z., Seneviratne C.J., Cheung G.S.P., Jin L., Zhao B. and Zhang C., Enterococcus faecalis promotes osteoclastogenesis and semaphorin 4D expression, Innate Immunity. 2015, 21: 726-735. |
| WANG Y., Liu H.H.L., Zhen Z., Yiu K.H., Tse H.F., Pelekos G. and Jin L., Periodontitis links with EPC counts in patients with T2 diabetes, Journal of Dental Research. 2016, 95 (Spec Iss B): 587. |
| Yang Y., LIAO C., Jin L. and Zhang C., IL-17 expression and its effect on osteoclastogenesis under mechanical loading, Journal of Dental Research. 2016, 95 (Spec Iss B): 1666. |
| ZHEN Z., CHEN Y., Liu J., Lai I.A., Jin L., Tse H.F. and Yiu K.H., Association of periodontitis with asymptomatic cardiac dysfunction in patients with diabetes, European Society Congress 2015. |
| Zhu J., Li X., Zhu F., Chen L., Zhang C., McGrath C.P.J., He F., Xiao Y. and Jin L., Multiple tooth loss is associated with vascular cognitive impairment in subjects with acute ischemic stroke, Journal of Periodontal Research. 2015, 50: 683-688. |
| Researcher : Lai IA |
| List of Research Outputs |
| ZHEN Z., CHEN Y., Liu J., Lai I.A., Jin L., Tse H.F. and Yiu K.H., Association of periodontitis with asymptomatic cardiac dysfunction in patients with diabetes, European Society Congress 2015. |
| Researcher : Leung WK |
| Project Title: | 79th General Session and Exhibition of the International Association for Dental Research Predominant Cultivable Subgingival Flora of Renal Transplant Recipients |
| Investigator(s): | Leung WK |
| Department: | Dental Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2001 |
| Project Title: | A randomized clinical trial using Rofecoxib as an adjunct to promote periodontal healing in non-surgical mechanical therapy on smokers |
| Investigator(s): | Leung WK |
| Department: | Dental Faculty |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 12/2003 |
| Project Title: | Four-dimensional analysis of human higher brain function during eating: functional MRI study of taste, mastication, and swallowing |
| Investigator(s): | Leung WK, Khong PL |
| Department: | Dental Faculty-OralDiagnosis&Polyclinics |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2012 |
| Completion Date: | 11/2015 |
| Project Title: | The role of periodontal resident cell TLR4 signaling and HIF-1α biology in modulating autophagy in human chronic periodontitis |
| Investigator(s): | Leung WK |
| Department: | Dental Faculty-OralDiagnosis&Polyclinics |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Project Title: | Protective effect of oral lining cells against anaerobic periodontal infection: Does microbe associated molecular pattern recognition interact with hypoxic preconditioning? |
| Investigator(s): | Leung WK, Fung ML, Tsao GSW |
| Department: | Dental Faculty-OralDiagnosis&Polyclinics |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2014 |
| Project Title: | In vitro study of salivary pellicle formation on dental restorative material surfaces. |
| Investigator(s): | Leung WK, Botelho MG |
| Department: | Dental Faculty-OralDiagnosis&Polyclinics |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2015 |
| Project Title: | Genetic risks for chronic periodontitis: A genome-wide association study |
| Investigator(s): | Leung WK, Song Y, Samartzis D, Cheah KSE, Cheung KMC, Sham PC, Chan D, Luk KDK |
| Department: | Dental Faculty-OralDiagnosis&Polyclinics |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | Turning risk into opportunity: biology of biofilm formation on dental restorative materials – maximizing the anti-plaque potential of fillings |
| Investigator(s): | Leung WK, Botelho MG |
| Department: | Dental Faculty-OralDiagnosis&Polyclinics |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 09/2015 |
| Project Title: | Analysis of microbial metagenome associated with periodontal disease |
| Investigator(s): | Leung WK, Watt RM, Chan YK |
| Department: | Dental Faculty-OralDiagnosis&Polyclinics |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2016 |
| List of Research Outputs |
| Chan Y.K., Yu X.L., Leung W.K. and Watt R.M., Comparative genomic analysis of phylogroup 1 oral treponeme strains, IADR/ APR General Session & Exhibition 2016; Periodontal Pathogens and Modulation of Host Immune Responses; Symposium 327B. Seoul, Korea, 2016. |
| Researcher : Pang KY |
| List of Research Outputs |
| LI X., Pang K.Y., Leung K.C.F. and Jin L., Cellular internalization and epithelial penetration of fluorescent-labeled mesoporous silica nanoparticles, Journal of Dental Research. 2016, 95 (Spec Iss B): 2022. |
| Leung K.C.F., Seneviratne C.J., LI X., Leung P.C., Lau C.B.S., Wong C.H., Pang K.Y., Wong C.W., Wat E. and Jin L., Synergistic Antibacterial Effects of Nanoparticles Encapsulated with Scutellaria baicalensis and Pure Chlorhexidine on Oral Bacterial Biofilms, Nanomaterials. 2016, 6: 61. |
| Researcher : Pelekos G |
| Project Title: | Expression profile of Porphyromonas gingivalis/LPS-induced inflammatory biomarkers in human reconstituted kidney epithelial cells |
| Investigator(s): | Pelekos G, Jin L |
| Department: | Dental Faculty - Periodontology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2015 |
| List of Research Outputs |
| Cheng C.K., Jin L. and Pelekos G., Halitosis and oral/periodontal conditions in Hong Kong adults, Journal of Dental Research. 2015, 94 (Spec Iss B): 240 (SEA Division). |
| Eng H. and Pelekos G., Effects of pregnancy on aggressive periodontitis disease progression, Journal of Dental Research. 2015, 94 (Spec Iss B): 238 (SEA Division). |
| Nibali L., Pelekos G., Onabolu O. and Donos N., Effect and timing of non-surgical treatment prior to periodontal regeneration: a systematic review, Clinical Oral Investigations. 2015, 19: 1755-1761. |
| Nibali L., Rizzo M., Li Volti G., D'Aiuto F., Giglio R.V., Barbagallo I., Pelekos G. and Donos L., Lipid subclasses profiles and oxidative stress in aggressive periodontitis before and after treatment, Journal of Periodontal Research. 2015, 50: 890-896. |
| Pelekos G. and Mardas N., Natural teeth or implants? Informating the decision-making process, Implant Practice. 2015, 8: 38-40. |
| WANG Y., Liu H.H.L., Zhen Z., Yiu K.H., Tse H.F., Pelekos G. and Jin L., Periodontitis links with EPC counts in patients with T2 diabetes, Journal of Dental Research. 2016, 95 (Spec Iss B): 587. |
| Researcher : Seneviratne CJ |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Seneviratne CJ |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 12/2011 |
| List of Research Outputs |
| Seneviratne C.J., Rajan S., Wong S.S.W., Tsang D.N.C., Lai C.K.C., Samaranayake L.P. and Jin L., Antifungal Susceptibility in Serum and Virulence Determinants of Candida Bloodstream Isolates from Hong Kong, Frontiers in Microbiology. 2016, 7: 216. |