DENTAL FACULTY - ORAL BIOSCIENCES



Researcher : Bhoj M

List of Research Outputs

Bhoj M., Zhang C. and Green D.W., A First Step in De Novo Synthesis of a Living Pulp Tissue Replacement Using Dental Pulp MSCs and Tissue Growth Factors, Encapsulated within a Bioinspired Alginate Hydrogel, Journal of Endodontics. 2015, 41: 1100-1107.


Researcher : Chan YK

Project Title:Oral Treponemes Phylogenomics: establishing a robust set of genetic markers
Investigator(s):Chan YK, Watt RM, Leung WK
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Small Project Funding
Start Date:03/2015


Project Title:London Calling 2016; Whole genome sequencing of an oral spirochete bacterium
Investigator(s):Chan YK
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2016
Completion Date:05/2016


List of Research Outputs

GAO W., Chan Y.K., Meng Y., Lacap-Bugler D.C., Leung W.K. and Watt R.M., In-depth snapshot of the equine subgingival microbiome, Microbial Pathogenesis. 2015.
Watt R.M., YU X., Chan Y.K. and Leung W.K., Distributions Of Synergistetes Bacteria Within Diseased and Asymptomatic Periodontal Niches, J Dent Res Vol # 94 (Spec Iss B):030 (SEA Division), 2015.
Watt R.M., YU X., Chan Y.K. and Leung W.K., Research Award in Periodontology and Microbiology, 29th Annual Scientific Meeting (2015) of the International Association for Dental Research, South-east Asian Division, International Association for Dental Research South-east Asian Division. 2015.
YU X., Chan Y.K., Zhuang L.F., Lai H.C., Lang N.P., Lacap-Bugler D.C., Leung W.K. and Watt R.M., Distributions of Synergistetes in clinically-healthy and diseased periodontal and peri-implant niches, Microbial Pathogenesis. 2015.


Researcher : Epasinghe DJ

List of Research Outputs

Ekambaram M., Epasinghe D.J., Yiu C.K.Y. and Matinlinna J.P., Effect of solvents on inhibition of collagen-bound proteases by chlorhexidine, International Journal of Adhesion and Adhesives. 2015, 60: 83-87.
Epasinghe D.J. and Jung H.S., Application Of Immobilization In Mouse Dental Papilla Cells For Bio Engineering Of The Tooth, Symposium On Tooth Development And Regeneration. 2016.
Epasinghe D.J., Yiu C.K.Y. and Burrow M.F., Effect of flavonoids on remineralization of artificial root caries, Australian Dental Journal. 2016, 61: 196-202.
Epasinghe D.J., Yiu C.K.Y. and Burrow M.F., Effect of proanthocyanidin incorporation into dental adhesive on durability of resin dentin bond, International Journal of Adhesion and adhesives. 2015, 63: 145-151.


Researcher : Jung HS

Project Title:Development and regeneration; Implications for total and partial reconstruction of the tooth by dental mesenchymal progenitor cells
Investigator(s):Jung HS
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2013


Project Title:Harnessing the osteogenic potential of marine biostructures in the development of a new dental "Bioimplant" for seniors (CRF)
Investigator(s):Jung HS
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Seed Funding for Incubating Group-based Collaborative Research Projects
Start Date:01/2015


Project Title:Wound Healing and Dermal Reconstruction to Control the Regenerative Skin
Investigator(s):Jung HS, Green DW
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:02/2015


Project Title:RUNX 2 mutations in supernumerary tooth formation among patients in Hong Kong, Japan and Sri Lanka
Investigator(s):Jung HS, Epasinghe DJ
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016


List of Research Outputs

Bhin J., Jeong H.S., Kim J.S., Shin J.O., Hong K.S., Jung H.S., Kim C., Hwang D. and Kim K.S., PGC-Enriched miRNAs Control Germ Cell Development, Molecules and Cells. 2015, 38(10): 895-903.
Epasinghe D.J. and Jung H.S., Application Of Immobilization In Mouse Dental Papilla Cells For Bio Engineering Of The Tooth, Symposium On Tooth Development And Regeneration. 2016.
Goto T., Yeung W.K.A., Tanabe H.C., Ito Y., Jung H.S. and Ninomiya Y., Enhancement of Combined Umami and Salty Taste by Glutathione in the Human Tongue and Brain, Chemical Senses. Oxford, 2016, 41: 623-630.
Green D.W., Ben-Nissan B., Yoon K.S., Milthorpe B. and Jung H.S., Bioinspired materials for regenerative medicine: going beyond the human archetypes, J. Mater. Chem. B. 2016, 4: 2396-2406.
Green D.W. and Jung H.S., Designer Supersurafaces via Bioinspiration and Biomimetics for Dental materials and Structures, Interface Oral Health Sciences 2014. 2015, 131-143.
Green D.W., Lee J.S. and Jung H.S., Small-Scale Fabrication of Biomimetic Structures for Periodontal Regeneration, Frontiers in Physiology. 2016, 7.
Kang C.M., Kim H., Song J.S., Choi B.J., Kim S.O., Jung H.S., Moon S.J. and Choi H.J., Genetic Comparison of Stemness of Human Umbilical Cord and Dental Pulp, Stem Cells International. 2016, 2016: 1-12.
Kwon H.J., Li L. and Jung H.S., The Hippo pathway/Yap regulates the primary enamel knot and dental cusp patterning in tooth morphogenesis, Cell and Tissue Research. 2015.
LAI M.C., Yiu C.K.Y., Jung H.S. and King N.M., Multipotency of mesenchymal stromal cells isolated from deciduous teeth, FDI Annual World Dental Congress. 2015.
Lee D.J., Jin C., Kim E.J., Lee J.M. and Jung H.S., Gastrin-releasing peptide expression and its effect on the calcification of developing mouse incisor, Histochemistry and Cell Biology. 2015.
Na J., Lee K., Na W., Shin J.Y., Lee M.J., Yune T.Y., Lee H.W., Jung H.S., Kim W.S. and Ju B.G., Histone H3K27 Demethylase JMJD3 in Cooperation with NF-κB Regulates Keratinocyte Wound Healing, Journal of Investigative Dermatology. 2016, 136: 847-858.
Tang Q., Li L., Lee M.J., Ge Q., Lee J.M. and Jung H.S., Novelo insights into a retinoic-acid-induced cleft palate based on Rac1 regulation of the fibronetin arrangement, Cell Tissue Research. 2016, 363(3): 713-22.
Tang Q., Li L., Jin C., Lee J.M. and Jung H.S., Role of region-distinctive expression of Rac1 in regulating fibronectin arrangement during palatal shelf elevation, Cell Tissue Res. 2015. 2015.


Researcher : Rajan S

List of Research Outputs

Seneviratne C.J., Rajan S., Wong S.S.W., Tsang D.N.C., Lai C.K.C., Samaranayake L.P. and Jin L., Antifungal Susceptibility in Serum and Virulence Determinants of Candida Bloodstream Isolates from Hong Kong, Frontiers in Microbiology. 2016, 7: 216.


Researcher : Samaranayake LP

Project Title:79th General Session and Exhibition of the International Association for Dental Research Turbidometric Evaluation of Polyene-azole Antagonism in C. Albicans
Investigator(s):Samaranayake LP
Department:Dental Faculty
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2001


Project Title:Proteomics of a fluconazole resistant, Candida glabrata strain
Investigator(s):Samaranayake LP, Samaranayake YH
Department:Dental Faculty
Source(s) of Funding:Small Project Funding
Start Date:02/2011


Project Title:Evaluation of biofilm interactions of Candida and gram negative bacteria on the catheter surface
Investigator(s):Samaranayake LP, Samaranayake YH
Department:Dental Faculty
Source(s) of Funding:Small Project Funding
Start Date:12/2011


List of Research Outputs

Seneviratne C.J., Rajan S., Wong S.S.W., Tsang D.N.C., Lai C.K.C., Samaranayake L.P. and Jin L., Antifungal Susceptibility in Serum and Virulence Determinants of Candida Bloodstream Isolates from Hong Kong, Frontiers in Microbiology. 2016, 7: 216.
Seneviratne C.J., Zeng G., Truong T., Wong S.S.W., Samaranayake L.P., Chan F.Y., Wang Y.M., Wang H. and Wang Y., New “haploid biofilm model” unravels IRA2 as a novel regulator of Candida albicans biofilm formation, Scientific Reports. 2015, 5.


Researcher : Seneviratne CJ

Project Title:Research Output Prize (Faculty of Dentistry)
Investigator(s):Seneviratne CJ
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Research Output Prize (in Faculty)
Start Date:12/2011


List of Research Outputs

Seneviratne C.J., Zeng G., Truong T., Wong S.S.W., Samaranayake L.P., Chan F.Y., Wang Y.M., Wang H. and Wang Y., New “haploid biofilm model” unravels IRA2 as a novel regulator of Candida albicans biofilm formation, Scientific Reports. 2015, 5.


Researcher : Tsang WK

Project Title:Generation of focused libraries by combinatorial biocatalysis with anti-Candidal activity: synthesis and in vitro study
Investigator(s):Tsang WK
Department:Dental Faculty
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Mini Grants
Start Date:01/2009


Project Title:Investigation of the functional significance of phytase activity in Candida albicans: gene disruption, pH regulation, and virulence study
Investigator(s):Tsang WK, Samaranayake LP
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:03/2012


Project Title:Perturbation of pH homeostasis: a comparative study on the inhibitory effect of purpurin on membrane-bound ATPases in Candida albicans
Investigator(s):Tsang WK, Samaranayake LP, Lam OLT
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:03/2013


Project Title:Research Output Prize (Faculty of Dentistry)
Investigator(s):Tsang WK
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Research Output Prize (in Faculty)
Start Date:01/2014




Researcher : Watt RM

Project Title:Raising the alarmone in Staphylococcus aureus: establishing the molecular basis of the stringent response
Investigator(s):Watt RM, Seneviratne CJ, Tanner JA
Department:Dental Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Research Output Prize (Faculty of Dentistry)
Investigator(s):Watt RM
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Research Output Prize (in Faculty)
Start Date:01/2013


Project Title:Whats in your pockets? Single-site analysis of Treponema and Synergistetes populations associated with periodontal health and disease
Investigator(s):Watt RM, Leung WK, Lacap-Bugler DC
Department:Dental Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Breaking the chain or making magic? Establishing the roles of polyphosphate hydrolase proteins in pathogenic bacteria
Investigator(s):Watt RM, Tanner JA, Lacap-Bugler DC
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Amine production and acid tolerance in oral treponemes: identifying species-specific and conserved pathways
Investigator(s):Watt RM, Leung WK
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2015


Project Title:Bark and Bite: a Comparative Genomics Approach to Unwind Uncertainties in Treponeme Biology, Taxonomy and Pathogenicity
Investigator(s):Watt RM, Leung WK, Chan YK
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:Cysteine proteases in oral Actinomyces: implications for disease pathology
Investigator(s):Watt RM
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016


List of Research Outputs

ACHARYA A., Koh M.L., Kheur S., Watt R.M., Jin L. and Mattheos N., Salivary IL-1β and red complex bacteria as predictors of the inflammatory status in sub-peri-implant niches of subjects with peri-implant mucositis, Clinical Oral Implants Research. 2016, 27: 662-667.
ACHARYA A., Kheur S., Gopalakrishnan D., Watt R.M., Jin L. and Mattheos N., Salivary interleukin-1b response is associated with microbiome diversity, Journal of Dental Research. 2016, 95 (Spec Iss B): 1247.
Botelho M.G., Lam O.L.T., Watt R.M. and Leung D.Y.P., Evaluation of peer-generated MCQs to assess and support learning in a problem-based learning programme., 2015 Faculty Annual Scientific Meeting. 2015.
GAO W., Chan Y.K., Meng Y., Lacap-Bugler D.C., Leung W.K. and Watt R.M., In-depth snapshot of the equine subgingival microbiome, Microbial Pathogenesis. 2015.
KHONG M.L., Li L., LU B., Watt R.M. and Tanner J.A., Determining proteins that specifically bind to polyphosphate in osteoblasts, Inorganic polyphosphate (polyP) physiology. Biochemical Society Hot Topic Event, London, UK. 2015.
Li L., KHONG M.L., Lu B., Buchet R., Watt R.M. and Tanner J.A., Long-chain inorganic polyphosphate is highly enriched in osteoblastic matrix vesicles., 40th FEBS Congress 2015 “The Biochemical Basis of Life”, Berlin, Germany (2015).. 2015.
Liu P., WEN W., Gao X., Watt R.M. and Wong M.C.M., Oral health problems and oral health-related quality-of-life among pregnant women, Journal of Dental Research. 2016, 95 (Spec Iss B): 354.
WEN W., Wong M.C.M., Gao X., Lo E.C.M. and Watt R.M., Dental visit and perceived need among Hong Kong pregnant women, Journal of Dental Research. 2015, 94 (Spec Iss B): 188 (SEA Division).
WEN W., Liu P., Lo E.C.M., Gao X., Watt R.M. and Wong M.C.M., Oral health promotion for pregnant women in Hong Kong, Journal of Dental Research. 2016, 95 (Spec Iss B): 259.
Watt R.M., YU X., Chan Y.K. and Leung W.K., Distributions Of Synergistetes Bacteria Within Diseased and Asymptomatic Periodontal Niches, J Dent Res Vol # 94 (Spec Iss B):030 (SEA Division), 2015.
Watt R.M., YU X., Chan Y.K. and Leung W.K., Research Award in Periodontology and Microbiology, 29th Annual Scientific Meeting (2015) of the International Association for Dental Research, South-east Asian Division, International Association for Dental Research South-east Asian Division. 2015.
Wen W., Lo E.C.M., Gao X., Watt R.M. and Wong M.C.M., Oral Health Promotion For Pregnant Women In Hong Kong, 2016 IADR. Jounal of Dental Research, 2016, 95 (Spec Iss B): 259.
YU X., Chan Y.K., Zhuang L.F., Lai H.C., Lang N.P., Lacap-Bugler D.C., Leung W.K. and Watt R.M., Distributions of Synergistetes in clinically-healthy and diseased periodontal and peri-implant niches, Microbial Pathogenesis. 2015.
Zhang A., Guo E., Q L., TANG N.Y., Watt R.M. and Bartlam M., Purification, crystallization and X-ray crystallographic analysis of a putative exopolyphosphatase from Zymomonas mobilis , Acta Crystallographica Section F Structural Biology Communications. 2016, 72: 172-178.


Researcher : Wong SSW

Project Title:Transcriptomic and proteomic view on cellular aging in the model of Candida albicans (OMICS biology perspective)
Investigator(s):Wong SSW, Jin L, Wang Y
Department:Dental Faculty - Oral Biosciences
Source(s) of Funding:Small Project Funding
Start Date:01/2015


List of Research Outputs

Seneviratne C.J., Rajan S., Wong S.S.W., Tsang D.N.C., Lai C.K.C., Samaranayake L.P. and Jin L., Antifungal Susceptibility in Serum and Virulence Determinants of Candida Bloodstream Isolates from Hong Kong, Frontiers in Microbiology. 2016, 7: 216.
Seneviratne C.J., Zeng G., Truong T., Wong S.S.W., Samaranayake L.P., Chan F.Y., Wang Y.M., Wang H. and Wang Y., New “haploid biofilm model” unravels IRA2 as a novel regulator of Candida albicans biofilm formation, Scientific Reports. 2015, 5.


Researcher : YU X

List of Research Outputs

Watt R.M., YU X., Chan Y.K. and Leung W.K., Distributions Of Synergistetes Bacteria Within Diseased and Asymptomatic Periodontal Niches, J Dent Res Vol # 94 (Spec Iss B):030 (SEA Division), 2015.
Watt R.M., YU X., Chan Y.K. and Leung W.K., Research Award in Periodontology and Microbiology, 29th Annual Scientific Meeting (2015) of the International Association for Dental Research, South-east Asian Division, International Association for Dental Research South-east Asian Division. 2015.
YU X., Chan Y.K., Zhuang L.F., Lai H.C., Lang N.P., Lacap-Bugler D.C., Leung W.K. and Watt R.M., Distributions of Synergistetes in clinically-healthy and diseased periodontal and peri-implant niches, Microbial Pathogenesis. 2015.


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