DEPT OF ANATOMY



Researcher : Chan CWY

Project Title:Human embryonic stem cell-derived cardiomyocyte as a model to study the role of autophagy in cardiac inflammation
Investigator(s):Chan CWY, Li RA
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:11/2013
Completion Date:11/2016




Researcher : Chan TK

Project Title:Redeveloping a governance model of the complaint-handling process for sufficient, accountable and transparent regulation of medical professionals in Hong Kong
Investigator(s):Chan TK
Department:Anatomy
Source(s) of Funding:Public Policy Research Funding Scheme
Start Date:01/2015




Researcher : Chang R.C.C.

Project Title:Significance of molecular signaling for protein translation control in neurodegeneration of amyotrophic lateral sclerosis
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Liu Po Shan/Dr Vincent Liu Endowment Fund for Motor Neuron diseases - General Award
Start Date:03/2008


Project Title:Elucidating pathological mechanisms of visual impairment in the pathogenesis of Alzheimer’s disease: from basic science to innovative approach of disease monitoring (CRF)
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Funding for Incubating Group-based Collaborative Research Projects
Start Date:01/2015
Completion Date:12/2016


Project Title:Elucidating the molecular defects associated with PTEN mutations in Autism Spectrum Disorders
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:04/2015


Project Title:Advancement for developing drug against Lewy Body Dementia by establishing a pre-clinical experimental model
Investigator(s):Chang RCC, Ho YS, Ng TW, Chu MT
Department:Anatomy
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:04/2015
Completion Date:12/2016


Project Title:Investigating oxyresveratrol as potential neuroprotective drug in experimental models of Parkinson’s disease
Investigator(s):Chang RCC, Ng KM, Wang M, Ho YS
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2015


Project Title:Investigation of drugs targeting mitochondrial dynamics and reactive oxygen species for Parkinson’s disease treatment using in vitro and in vivo imaging models
Investigator(s):Chang RCC, Hung HLC
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2015


Project Title:Investigating the significance of JNK3 and PKR in modulating the fate of neurons in cigarette smoking-induced neurodegeneration as risk factor of Alzheimer's disease
Investigator(s):Chang RCC, Ho YS
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2016


Project Title:Establishment of pre-clinical platform and a novel 3D tissue visualisation protocol for therapeutic drug development of Lewy Body Dementias
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:09/2016


Project Title:Society for Neuroscience 2016; Development of tissue clearing techniques for the visualisation of neurodegenerative pathology in three-dimensions
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2016
Completion Date:11/2016


Project Title:Significance of frontal cortex in the progression of Alzheimer’s disease
Investigator(s):Chang RCC, Ho YS
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2017




Researcher : Chang RCC

Project Title:Significance of molecular signaling for protein translation control in neurodegeneration of amyotrophic lateral sclerosis
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Liu Po Shan/Dr Vincent Liu Endowment Fund for Motor Neuron diseases - General Award
Start Date:03/2008


Project Title:Elucidating pathological mechanisms of visual impairment in the pathogenesis of Alzheimer’s disease: from basic science to innovative approach of disease monitoring (CRF)
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Funding for Incubating Group-based Collaborative Research Projects
Start Date:01/2015
Completion Date:12/2016


Project Title:Elucidating the molecular defects associated with PTEN mutations in Autism Spectrum Disorders
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:04/2015


Project Title:Advancement for developing drug against Lewy Body Dementia by establishing a pre-clinical experimental model
Investigator(s):Chang RCC, Ho YS, Ng TW, Chu MT
Department:Anatomy
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:04/2015
Completion Date:12/2016


Project Title:Investigating oxyresveratrol as potential neuroprotective drug in experimental models of Parkinson’s disease
Investigator(s):Chang RCC, Ng KM, Wang M, Ho YS
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2015


Project Title:Investigation of drugs targeting mitochondrial dynamics and reactive oxygen species for Parkinson’s disease treatment using in vitro and in vivo imaging models
Investigator(s):Chang RCC, Hung HLC
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2015


Project Title:Investigating the significance of JNK3 and PKR in modulating the fate of neurons in cigarette smoking-induced neurodegeneration as risk factor of Alzheimer's disease
Investigator(s):Chang RCC, Ho YS
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2016


Project Title:Establishment of pre-clinical platform and a novel 3D tissue visualisation protocol for therapeutic drug development of Lewy Body Dementias
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:09/2016


Project Title:Society for Neuroscience 2016; Development of tissue clearing techniques for the visualisation of neurodegenerative pathology in three-dimensions
Investigator(s):Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2016
Completion Date:11/2016


Project Title:Significance of frontal cortex in the progression of Alzheimer’s disease
Investigator(s):Chang RCC, Ho YS
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2017




Researcher : Chau RMW

Project Title:HUGO's Seventh International Human Genome Meeting, HGM2002 The Possible Mechanism of Action for Quinacrine Interacting the Scrapie Protein in Prion Disease
Investigator(s):Chau RMW
Department:Anatomy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2002




Researcher : Chen AYS

Project Title:Study of the role of polyol pathway activation the impaired nerve regeneration in diabetes
Investigator(s):Chen AYS, Chung SK
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:12/2008




Researcher : Cheung MCH

Project Title:In vivo functional characterization of a Rho GTPase-activating protein, DLC1, in neural crest development
Investigator(s):Cheung MCH
Department:School of Biomedical Sciences
Source(s) of Funding:Early Career Scheme (ECS)
Start Date:10/2014


Project Title:Elucidating the contribution of cross-regulatory interactions between SOX9 and SOX10 to melanoma progression
Investigator(s):Cheung MCH, Lung HL
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:08/2016


Project Title:Elucidating the role of Sox9 in cell fate acquisition of neural crest progenitors in the dorsal root ganglia
Investigator(s):Cheung MCH, Sham MH, Lui VCH, Cheah KSE
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2015


Project Title:Elucidating the role of Dlc1beta in motor neuron development
Investigator(s):Cheung MCH
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2016


Project Title:Elucidating the therapeutic potential of neural stem cells with genetic manipulation of Sox9 expression following spinal cord injury
Investigator(s):Cheung MCH, Wu W, Cheah KSE
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2016


Project Title:Elucidating the role of Deleted in Liver Cancer-1 (DLC1) in melanoma development and therapy
Investigator(s):Cheung MCH, Guan X
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017




Researcher : Ching Y.P.

Project Title:Roles of p21-activated protein kinase (Pak) 1 in the pathogenesis of liver cancer
Investigator(s):Ching YP, Ng IOL, Jin D, Yau TO
Department:Pathology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006


Project Title:HBx oncoprotein induces chromosome instability in hepatocarcinogenesis via dysregulation of centrosome duplication regulatory protein, TAX1BP2
Investigator(s):Ching YP, Jin D
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:03/2013
Completion Date:10/2016


Project Title:Functional characterization of the roles of NIMA-related kinase, Nek2 in liver cancer development and metastasis
Investigator(s):Ching YP, Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:The therapeutic potential of Polo-like protein kinase 4 in liver cancer
Investigator(s):Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2015
Completion Date:03/2017


Project Title:A study of the role of CDK5RAP3 in neuronal cell differentiation
Investigator(s):Ching YP, Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2015


Project Title:Functional characterization of the roles of Polo-like kinase 4, Plk4 in hepatocarcinogenesis
Investigator(s):Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:Characterization of novel HBx regulated gene in hepatocellular carcinoma
Investigator(s):Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016


Project Title:A study of the role of p21-activated kinase 4 (PAK4) in chromosome instability
Investigator(s):Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017




Researcher : Ching YP

Project Title:Roles of p21-activated protein kinase (Pak) 1 in the pathogenesis of liver cancer
Investigator(s):Ching YP, Ng IOL, Jin D, Yau TO
Department:Pathology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006


Project Title:HBx oncoprotein induces chromosome instability in hepatocarcinogenesis via dysregulation of centrosome duplication regulatory protein, TAX1BP2
Investigator(s):Ching YP, Jin D
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:03/2013
Completion Date:10/2016


Project Title:Functional characterization of the roles of NIMA-related kinase, Nek2 in liver cancer development and metastasis
Investigator(s):Ching YP, Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:The therapeutic potential of Polo-like protein kinase 4 in liver cancer
Investigator(s):Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2015
Completion Date:03/2017


Project Title:A study of the role of CDK5RAP3 in neuronal cell differentiation
Investigator(s):Ching YP, Chang RCC
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2015


Project Title:Functional characterization of the roles of Polo-like kinase 4, Plk4 in hepatocarcinogenesis
Investigator(s):Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:Characterization of novel HBx regulated gene in hepatocellular carcinoma
Investigator(s):Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016


Project Title:A study of the role of p21-activated kinase 4 (PAK4) in chromosome instability
Investigator(s):Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017




Researcher : Chung SK

Project Title:Stem Cell Strategy for Nervous System Disorders
Investigator(s):Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:Theme-based Research Scheme
Start Date:09/2012


Project Title:Aldose Reductase(AR) effect dopaminergic neuronal autophagy through microglia after acute inflammation in Parkinson’s disease
Investigator(s):Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2015


Project Title:To determine the role of Exchange Proteins Directly Activated by cAMP (Epac) in the gut microbiota-mediated metabolic syndrome
Investigator(s):Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2015


Project Title:Molecular basis of beta3-adrenergic receptor agonists on anxiolytic-and anti-depressive action: cAMP/Epac2 as a potential signal to improve neuronal mitochondrial biogenesis and neurogenesis.
Investigator(s):Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2016


Project Title:To determine the role of exchange protein directly activated by cAMP in the blood-retinal barrier and pathogenesis of diabetic retinopathy
Investigator(s):Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2016


Project Title:Interaction between activated aldose reductase, non-enzymatic glycation, PKC and hexosamine pathways for the pathogenesis of diabetic complications
Investigator(s):Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2016


Project Title:Cellular Mechanisms of Synaptic Functions and Plasticity in Health and Neurodegenerative Diseases
Investigator(s):Chung SK
Department:School of Biomedical Sciences
Source(s) of Funding:Areas of Excellence Scheme
Start Date:06/2017


List of Research Outputs

Chua W.H., Wong K.K.L., BC K.O., Chung S.K., Lee L.T.O. and Chow B.K.C., Role of nuclear factor of activated T-cells 5 in regulating hypertonic-mediated secretin receptor expression in kidney collecting duct cells, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2016, 1859: 922-932.


Researcher : Deng W

Project Title:Role of Bmi-1 in the persistence of Epstein-Barr virus (EBV) in nasopharyngeal epithelial cells
Investigator(s):Deng W, Tsao GSW, Huen MSY, Tsang CM
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013
Completion Date:08/2016


Project Title:A novel function of IL-6/IL-6R?signaling activation in nasopharyngeal epithelial cells: facilitation of cellular immortalization
Investigator(s):Deng W, Tsao GSW, Chen H
Department:School of Nursing
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Immortalization of human uterine cervical epithelial cells without viral oncogene expression
Investigator(s):Deng W, Tsao GSW
Department:School of Nursing
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2015
Completion Date:02/2017


Project Title:Role of IL-6/IL-6Rα signaling activation in supporting persistent EBV infection in premalignant nasopharyngeal epithelial cells
Investigator(s):Deng W, Tsao GSW
Department:School of Nursing
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2017




Researcher : Deng W.

Project Title:Role of Bmi-1 in the persistence of Epstein-Barr virus (EBV) in nasopharyngeal epithelial cells
Investigator(s):Deng W, Tsao GSW, Huen MSY, Tsang CM
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013
Completion Date:08/2016


Project Title:A novel function of IL-6/IL-6R?signaling activation in nasopharyngeal epithelial cells: facilitation of cellular immortalization
Investigator(s):Deng W, Tsao GSW, Chen H
Department:School of Nursing
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Immortalization of human uterine cervical epithelial cells without viral oncogene expression
Investigator(s):Deng W, Tsao GSW
Department:School of Nursing
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2015
Completion Date:02/2017


Project Title:Role of IL-6/IL-6Rα signaling activation in supporting persistent EBV infection in premalignant nasopharyngeal epithelial cells
Investigator(s):Deng W, Tsao GSW
Department:School of Nursing
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2017




Researcher : Feng W

Project Title:Maintenance of Genome Stability 2014; A role of NIRR in replicative stress responses
Investigator(s):Feng W
Department:Anatomy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2014




Researcher : Hugon J

Project Title:Society for Neuroscience 30th Annual Meeting Tau Phosphorylation during neuronal Apoptosis Induced by NMDA Receptor Blockade: an in Vivo Study
Investigator(s):Hugon J
Department:Anatomy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2000




Researcher : Lin B

Project Title:Modulation of the PTEN/mTOR pathway enhances the survival of cone photoreceptors in retinal degeneration disorders
Investigator(s):Lin B, Ching YP
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:12/2013
Completion Date:07/2016


Project Title:Ectopic expression of the light-sensitive protein melanopsin in rod photoreceptors prevents retinal degeneration
Investigator(s):Lin B
Department:Anatomy
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015
Completion Date:07/2016


Project Title:Cyclooxygenase-1 deletion promotes microglia quiescence and enhances cone photoreceptor survival in retinal degeneration disorders
Investigator(s):Lin B, Ching YP
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2015
Completion Date:07/2016


Project Title:Inhibition of colony-stimulating factor 1 receptor signaling in microglia delays the progression of the chronic neurodegeneration in retinitis pigmentosa
Investigator(s):Lin B
Department:Anatomy
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2015
Completion Date:07/2016


Project Title:Inhibition of colony-stimulating factor 1 receptor (CSF1R) signaling in microglia delays the progression of the chronic neurodegeneration in retinitis pigmentosa
Investigator(s):Lin B
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016
Completion Date:07/2016


Project Title:annual meeting of the association for research in vision and ophthalmology ; PTEN deletion enhances the survival of cone photoreceptors in retinal degeneration disorders
Investigator(s):Lin B
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2016




Researcher : Ling MT

Project Title:The regulation and role of Id-1 in prostate cancer progression
Investigator(s):Ling MT, Wong YC, Wang X
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:The role of EMI1 in prostate carcinogenesis
Investigator(s):Ling MT, Wang X
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:02/2007


Project Title:The role of Daxx in chromosome instability and prostate carcinogenesis
Investigator(s):Ling MT, Wong YC
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2008




Researcher : Liu J

List of Research Outputs

Cheung A., Li B., Xu W., Liu J. and Chan K.W., miR-29c modulates chemoresistance in esophageal cancer cells by suppressing FBXO31, European Journal of Cancer (24th Biennial Congress of the European Association for Cancer Research). 2016, 61 Suppl 1: S64.


Researcher : Ma SKY

Project Title:Hepatitis B virus promotes hepatocarcinogenesis through induction of CD133+ cancer stem cells/tumor-initiating cells
Investigator(s):Ma SKY, Guan X
Department:Clinical Oncology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013
Completion Date:10/2016


Project Title:Significance of Annexin A3 in CD133+ Cancer-Initiating Cells-Driven Hepatocellular Carcinoma
Investigator(s):Ma SKY, Chan KW
Department:Clinical Oncology
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2013
Completion Date:11/2016


Project Title:Outstanding Young Researcher Award 2012-13
Investigator(s):Ma SKY
Department:Anatomy
Source(s) of Funding:Outstanding Young Researcher Award
Start Date:01/2014


Project Title:A multidisciplinary study on hepatic cancer stem cells
Investigator(s):Ma SKY
Department:School of Biomedical Sciences
Source(s) of Funding:Croucher Innovation Awards
Start Date:04/2014


Project Title:Regulatory role of microRNA-1246 and Wnt/β-catenin pathway interaction in CD133+ liver cancer stem cells-driven hepatocellular carcinoma
Investigator(s):Ma SKY
Department:School of Biomedical Sciences
Source(s) of Funding:Early Career Scheme (ECS)
Start Date:01/2015


Project Title:PRMT6 in the control of glucose metabolic reprogramming in CD133+ liver cancer stem cells
Investigator(s):Ma SKY
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2015
Completion Date:08/2016


Project Title:A Multidisciplinary Study on CD133 Liver Cancer Stem Cells: Molecular Mechanisms, Clinical Relevance and Therapeutic Implications
Investigator(s):Ma SKY, Guan X, Lo CM, Man K
Department:School of Biomedical Sciences
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2015


Project Title:PRMT6 regulates ERK1/2 signal transduction in liver cancer through CRAF
Investigator(s):Ma SKY
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016
Completion Date:09/2017


Project Title:Establishment of a novel ANXA3 neutralizing antibody and its use, alone or in combination with sorafenib, as a potential therapeutic regimen against liver cancer
Investigator(s):Ma SKY
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:05/2016
Completion Date:04/2017


Project Title:Role of PRMT6 in regulating cancer and stemness properties in hepatocellular carcinoma
Investigator(s):Ma SKY, Leung SY, Yan HHN
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2016


Project Title:AACR Annual Meeting; Octamer-4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells
Investigator(s):Ma SKY
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2017
Completion Date:04/2017


Project Title:Role of MAPK11 in liver cancer stem cells
Investigator(s):Ma SKY
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


Project Title:A Multidisciplinary Study on CD133 Liver Cancer Stem Cells: Molecular Mechanisms, Clinical Relevance and Therapeutic Implications (CRF)
Investigator(s):Ma SKY
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Funding for Strategic Interdisciplinary Research Scheme
Start Date:06/2017




Researcher : Ng KY

Project Title:Role of LOXL1 in CD133+ liver cancer stem cells driven hepatocellular carcinoma
Investigator(s):Ng KY, Huen MSY, Ma SKY
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:05/2015
Completion Date:10/2016


Project Title:AACR Annual Meeting 2017; TP53INP1 negatively regulates ERK1/2 via p73-dependent DUSP10 expression to promote metastasis in hepatocellular carcinoma
Investigator(s):Ng KY
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2017
Completion Date:04/2017




Researcher : Ng TW

Project Title:Evaluating the effect of prostaglandin-E2 EP4 receptor signaling
Investigator(s):Ng TW, Chang RCC
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:04/2015
Completion Date:09/2016




Researcher : So K.F.

Project Title:Minimizing neuropsychiatric side-effects of glucocorticoid therapy by antipsychotics and Chinese medicine
Investigator(s):So KF, Lee TMC, Chang RCC, Ching YP
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014
Completion Date:11/2016


Project Title:Study of gliogenesis and neurochemistry underlying psychomotor retardation induced by chronic stress and the therapeutic approach for motor training in reversing the adverse effects
Investigator(s):So KF, Wu W, Lee TMC
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


Project Title:Potential Role of Adiponectin Signaling in Mediating Physical Exercise-Elicited Hippocampal Neurogenesis and Antidepressive Effects in Stressed Mice
Investigator(s):So KF, Xu A
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015




Researcher : So KF

Project Title:Minimizing neuropsychiatric side-effects of glucocorticoid therapy by antipsychotics and Chinese medicine
Investigator(s):So KF, Lee TMC, Chang RCC, Ching YP
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014
Completion Date:11/2016


Project Title:Study of gliogenesis and neurochemistry underlying psychomotor retardation induced by chronic stress and the therapeutic approach for motor training in reversing the adverse effects
Investigator(s):So KF, Wu W, Lee TMC
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


Project Title:Potential Role of Adiponectin Signaling in Mediating Physical Exercise-Elicited Hippocampal Neurogenesis and Antidepressive Effects in Stressed Mice
Investigator(s):So KF, Xu A
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015




Researcher : Sy MH

Project Title:Regulation of Microcephalin (MCPH1) by the Herpes Simplex Virus Type 1 Regulatory Protein ICP0
Investigator(s):Sy MH, Huen MSY
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:The role of DNA Damage and Repair Signaling in Hepatocarcinogenesis
Investigator(s):Sy MH, Huen MSY
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2015




Researcher : Sy SMH

Project Title:Regulation of Microcephalin (MCPH1) by the Herpes Simplex Virus Type 1 Regulatory Protein ICP0
Investigator(s):Sy MH, Huen MSY
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:The role of DNA Damage and Repair Signaling in Hepatocarcinogenesis
Investigator(s):Sy MH, Huen MSY
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2015




Researcher : TIRRELL L

List of Research Outputs

FENG R., TIRRELL L., Cheung C.W. and Chung S.K., Deleted in Liver Cancer 2-deficiency Lead to more Severe Inflammatory Pain in Diabetic Mice with Altered Nerve Morphology and Activated RhoA/pERK/NF7, 21st Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2016.


Researcher : Tipoe GL

Project Title:23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL); Polysaccharides from Lycium barbarum attenuates hepatic steatosis, fibrosis and inflammation in non-alcoholic liver diseases (NAFLD) rat model
Investigator(s):Tipoe GL
Department:Anatomy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2013


Project Title:The regulation of cylcooxygenase-1 in a carbon tetrachloride induced acute liver injury animal model
Investigator(s):Tipoe GL
Department:School of Biomedical Sciences
Source(s) of Funding:Small Project Funding
Start Date:04/2015
Completion Date:06/2017


Project Title:Therapeutic effects of Wolfberry (Lycium barbarum polysaccharides; LBP) in non-alcoholic fatty liver disease (NAFLD) animal models
Investigator(s):Tipoe GL, So KF
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2015


Project Title:Novel anti-hepatic cancer properties of garlic-derived SAMC through direct targeting of LRP6/Wnt signaling pathway
Investigator(s):Tipoe GL
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016
Completion Date:07/2017


Project Title:Defining the protective functional role of cyclooxygenase-1 in acute and chronic liver diseases
Investigator(s):Tipoe GL, Ching YP
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2016


Project Title:Mechanisms underlying the ameliorative effects of chronic aerobic exercise in non-alcoholic steatohepatitis
Investigator(s):Tipoe GL
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2017




Researcher : Tong M

Project Title:The clinical and functional significances of glucose transporter, isoform 3 (GLUT3) in CD133+ liver cancer stem cells driven Hepatocellular carcinoma
Investigator(s):Tong M, Ma SKY
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:08/2016


Project Title:American Association for Cancer Research Annual Meeting 2017; Targeting ANXA3 in combination with sorafenib for the treatment of hepatocellular carcinoma
Investigator(s):Tong M
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2017
Completion Date:04/2017




Researcher : Tsao G.S.W.

Project Title:The role of TGF-beta in EBV infection and pathogenesis of nasopharyngeal carcinoma
Investigator(s):Tsao GSW, Lan HY
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:01/2009


Project Title:Systematic Development of Molecular Targets for Nasopharyngeal Carcinoma
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:Theme-based Research Scheme
Start Date:01/2014


Project Title:Dynamics of EBV episome maintenance in infected nasopharyngeal epithelial cells
Investigator(s):Tsao GSW, Chen H, Deng W
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Regulation of invadopodia formation by the EBV-encoded LMP1 in nasopharyngeal epithelial cells
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Delineating the signal pathways of LMP1 in the activation of mTOR signaling in nasopharyngeal carcinoma cells
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2015
Completion Date:04/2017


Project Title:Establishment of a shared live cell imaging platform for super-resolution microscopy
Investigator(s):Tsao GSW, Bruzzone R, Chang RCC, Cheung MCH, Ching YP, Huen MSY, Jin D, Yang D, Yu C, Yuen KWY
Department:Anatomy
Source(s) of Funding:Collaborative Research Fund (CRF) - Major Equipment Project
Start Date:06/2015


Project Title:Advanced Imaging - From System Biology to Single Cell & Single Molecule Analysis
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:Croucher Summer Courses
Start Date:07/2015


Project Title:Biomimetic 3D Microsystem to Study Tumour Survival and Drug Responses
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2016


Project Title:Immortalization of nasopharyngeal epithelial cells by the EBV-encoded LMP1
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2016


Project Title:American Association for Cancer Research Annual Conference 2017; The role of EBV infection in aerobic glycolysis in nasopharyngeal carcinoma
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2017
Completion Date:04/2017


Project Title:High speed and high-sensitivity fluorescent live cell imaging system
Investigator(s):Tsao GSW, Yu C
Department:Anatomy
Source(s) of Funding:Small Equipment Grant
Start Date:06/2017


Project Title:Preclinical evaluation of therapeutic use of a selective cdk4/6 inhibitor (PD-0332991) in nasopharyngeal carcinoma (NPC).
Investigator(s):Tsao GSW, Lui WYV, Lee WMA
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2017


Project Title:Regulation and pathogenic role of latent infection of Epstein-Barr virus in nasopharyngeal carcinoma
Investigator(s):Tsao GSW, Chen H, Jin D, Kok KH
Department:School of Biomedical Sciences
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2017




Researcher : Tsao GSW

Project Title:The role of TGF-beta in EBV infection and pathogenesis of nasopharyngeal carcinoma
Investigator(s):Tsao GSW, Lan HY
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:01/2009


Project Title:Systematic Development of Molecular Targets for Nasopharyngeal Carcinoma
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:Theme-based Research Scheme
Start Date:01/2014


Project Title:Dynamics of EBV episome maintenance in infected nasopharyngeal epithelial cells
Investigator(s):Tsao GSW, Chen H, Deng W
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Regulation of invadopodia formation by the EBV-encoded LMP1 in nasopharyngeal epithelial cells
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Delineating the signal pathways of LMP1 in the activation of mTOR signaling in nasopharyngeal carcinoma cells
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2015
Completion Date:04/2017


Project Title:Establishment of a shared live cell imaging platform for super-resolution microscopy
Investigator(s):Tsao GSW, Bruzzone R, Chang RCC, Cheung MCH, Ching YP, Huen MSY, Jin D, Yang D, Yu C, Yuen KWY
Department:Anatomy
Source(s) of Funding:Collaborative Research Fund (CRF) - Major Equipment Project
Start Date:06/2015


Project Title:Advanced Imaging - From System Biology to Single Cell & Single Molecule Analysis
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:Croucher Summer Courses
Start Date:07/2015


Project Title:Biomimetic 3D Microsystem to Study Tumour Survival and Drug Responses
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2016


Project Title:Immortalization of nasopharyngeal epithelial cells by the EBV-encoded LMP1
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2016


Project Title:American Association for Cancer Research Annual Conference 2017; The role of EBV infection in aerobic glycolysis in nasopharyngeal carcinoma
Investigator(s):Tsao GSW
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2017
Completion Date:04/2017


Project Title:High speed and high-sensitivity fluorescent live cell imaging system
Investigator(s):Tsao GSW, Yu C
Department:Anatomy
Source(s) of Funding:Small Equipment Grant
Start Date:06/2017


Project Title:Preclinical evaluation of therapeutic use of a selective cdk4/6 inhibitor (PD-0332991) in nasopharyngeal carcinoma (NPC).
Investigator(s):Tsao GSW, Lui WYV, Lee WMA
Department:Anatomy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2017


Project Title:Regulation and pathogenic role of latent infection of Epstein-Barr virus in nasopharyngeal carcinoma
Investigator(s):Tsao GSW, Chen H, Jin D, Kok KH
Department:School of Biomedical Sciences
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2017




Researcher : Wang X

Project Title:Angio-(1-7) and ACE2 during normal and hypertensive pregnancy
Investigator(s):Wang X, Ellis-Behnke RG
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:12/2008




Researcher : Wong LLY

List of Research Outputs

Xu H.T., Lai W.L., Liu H.F., Wong L.L.Y., Ng I.O.L. and Ching Y.P., PAK4 phosphorylates p53 at serine 215 to promote liver cancer metastasis., Cancer Research. American Association for Cancer Research., 2016, 76: 5732-5742.


Researcher : Wong YC

Project Title:Induction of breast carcinogenesis by a combination of androgens and oestrogens
Investigator(s):Wong YC, Xie B
Department:Anatomy
Source(s) of Funding:Other Funding Scheme
Start Date:07/1997


Project Title:The Beijing, Hong Kong and UK Collaborative Study on the Molecular Genetic Basis of Differential Susceptibility of Prostate Cancer Between Chinese and Caucasian
Investigator(s):Wong YC, Wang X, Ho KMT
Department:School of Biomedical Sciences
Source(s) of Funding:The University of Hong Kong Foundation Seed Grant
Start Date:07/2003




Researcher : Wu W

Project Title:Effects of chondroitinase ABC and lithium chloride on neuronal survival and regeneration after spinal cord injury
Investigator(s):Wu W, Yick LW, So KF
Department:Anatomy
Source(s) of Funding:Matching Fund for National Key Basic Research Development Scheme (973 Projects)
Start Date:11/2003


Project Title:Research Output Prize
Investigator(s):Wu W, Su H, Wong WM, So KF, Wu EX
Department:Anatomy
Source(s) of Funding:Research Output Prize (in Faculty)
Start Date:10/2008


Project Title:Spinal cord injury in developing and adult rats: different outcome and potential mechanisms.
Investigator(s):Wu W
Department:School of Biomedical Sciences
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2015
Completion Date:02/2017


Project Title:Repairing neural damage after spinal cord injury with self-assembling peptide nanofiber scaffold (SAPNS)
Investigator(s):Wu W
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


Project Title:Enhancing axonal regeneration of spinal motoneurons after root avulsion by manipulation of chondroitin sulfate proteoglycans (CSPGs)
Investigator(s):Wu W, Huang J
Department:School of Biomedical Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2016


Project Title:the 2016 Tissue Engineering and Regenerative Medicine International Society- Asia Pacific Meeting (TERMIS-AP 2016); Repairing damage in the nervous tissue with biomaterials and neural stem cells
Investigator(s):Wu W
Department:School of Biomedical Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2016
Completion Date:09/2016




Researcher : Yang J

Project Title:Investigation of physiology and possible neuroprotective effect of the retinal microglia under normal and glaucoma conditions
Investigator(s):Yang J, So KF, Chang RCC
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:11/2008




Researcher : Yeung PKK

Project Title:The Effectiveness of Vasopressin V1 receptor antagonist , SR49059, and V2 Receptor Anatongist, OPC-31260, on Cerebral Edema Formation in Endothelin-1-Overexpressed Mice
Investigator(s):Yeung PKK, Chung SK
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:09/2008




Researcher : Yip HKF

Project Title:In vivo gene transfer of the catalytic subunit of telomerase protects retinal ganglion cells against axotomy-induced cell death
Investigator(s):Yip HKF, Tsao GSW, Chung SK
Department:Anatomy
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2005


Project Title:Telomerase immortalization of retinal ganglion cells derived from the embryonic mouse retinal progenitor cells
Investigator(s):Yip HKF, Tsao GSW
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:01/2009


Project Title:Combined treatment of lithium and noggin inhibits astroglios after spinal cord injury by deactivation of GSK-3β/STAT3 are BMP/Smad pathways in the endogenous adult neural stem cells
Investigator(s):Yip HKF, Shum DKY
Department:School of Biomedical Sciences
Source(s) of Funding:Spinal Cord Injury Research Grant
Start Date:05/2010


Project Title:Lithium treatment increases the expression of brain-derived neurotrophic factor in the injured adult spinal cord.
Investigator(s):Yip HKF
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:08/2016




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