DEPT OF ANAESTHESIOLOGY



Researcher : Cai Y

List of Research Outputs

Cai Y., PANG L., Tang E.H.C., Irwin M.G. and Xia Z., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis viaAkt-dependent enhancentment of iNOS expression, 14th Annual Meeting of the Society for Heart and Vascular Metabolism. 2016.
Cai Y., University of Hong Kong/China Medical Board Grant, University of Hong Kong; China Medical Board. 2017.
YING F., Cai Y., Wong H.K., Lee T. and Tang E.H.C., Disturbed cholesterol homeostasis in prostaglandin E receptor 4 knockout mice model, The 6th ICCR Congress on Chronic societal Cardiometabolic Diseases. 2017.
YING F., Cai Y., CAI Y., Wang Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 regulates lipid droplet size and mitochondrial activity in murine subcutaneous white adipose tissue, The FASEB Journal. 2017, 331: 4023-4036.


Researcher : Chan TCW

List of Research Outputs

Chan W.K., Chan P.K., Chiu P.K.Y., Yan C.H., Fu C.H.H. and Chan T.C.W., Bronze Award, Best Original Research by Trainee, Hong Kong Academy of Medicine. 2016.
Chan W.K., Chan P.K., Chiu P.K.Y., Yan C.H., Fu C.H.H., Ng F.Y. and Chan T.C.W., Vincent Chan trophy for the best paper on adult joint reconstruction by trainee, Hong Kong Orthopaedic Association. 2016.
Cheung C.W., Chan T.C.W., Chen P.P., Chu M.C., Chui W.C.M., HO P.T., Lam F., Law S.W., Lee J.L.Y., Wong S.H.S. and Wong V.K.C., Opioid therapy for chronic non cancer pain: Guidelines for the Hong Kong Setting, Hong Kong Medical Journal. 2016, 22(5): 496-505.


Researcher : Cheung CW

Project Title:Implantation of intrathecal pump for cancer pain patients
Investigator(s):Cheung CW, Tsang WHJ
Department:Anaesthesiology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2012


Project Title:Cash donation to support service and clinical research (Pain Management)
Investigator(s):Cheung CW, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:Cash donation for supporting service and clinical research
Start Date:11/2013


Project Title:Central CXCL12/CXCR4 axis contributes to the induction of peripheral neuropathic pain
Investigator(s):Cheung CW, Irwin MG, Wong SCS
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:01/2015


List of Research Outputs

Cheung C.W., Analgesia induced by spinal cord stimulation following spinal cord injury associated with the activation of neuronal progenitor cells, 13th World Congress of International Neuromodulation Society. 27 May to 1 June 2017. 2017.
Cheung C.W., Chairman, Are we sedating our patients optimally? Current Concepts and Updated, 16th World Congress of Anaesthesiologists, 31 August 2016, Hong Kong. 2016.
Cheung C.W., Chairman, Chronic Pain Management, AbbVie symposium in Hong Kong during the 16th World Congress of Anaesthesiologists, 31 August 2016, Hong Kong. 2016.
Cheung C.W., Chairman, How to get the most out of your inhaled anaesthetic?, AbbVie symposium in Hong Kong during the 16th World Congress of anaesthesiologists, 31 August 2016, Hong Kong. 2016.
Cheung C.W., Chairman. Current Status of Clinical Research on Acupunture, International Scientific Acupuncture and Meridian Symposium 2016 - Acupuncture: Health and Wellbeing. Hong Kong. 18th November 2016. 2016.
Cheung C.W., Chairman. Pfizer's Sedation Symposium and Panel Discussion: Are we sedating our patients optimally? Current concepts and updated, 16th World Congress of Anaesthesiologists. Hong Kong. 29th August 2016. 2016.
Cheung C.W., Choi S.W., Wong S.C.S., Lee Y. and Irwin M.G., Changes in prevalence, outcomes and help seeking behaviour of chronic pain in an aging population over the last decade, Pain Practice. 2016.
Cheung C.W., Chan T.C.W., Chen P.P., Chu M.C., Chui W.C.M., HO P.T., Lam F., Law S.W., Lee J.L.Y., Wong S.H.S. and Wong V.K.C., Opioid therapy for chronic non cancer pain: Guidelines for the Hong Kong Setting, Hong Kong Medical Journal. 2016, 22(5): 496-505.
Cheung C.W., Wong S.C.S., Qiu Q. and Wang X.M.A., Oral oxycodone for acute postoperative pain: a narrative review of clinical trails, Pain Physician. 2017, 20(2S): SE33-SE52.
Cheung C.W., Peer Reviewer, Academy of Medicine, Singapore. 2017.
Cheung C.W., Peer Reviewer, Analgesia and Anesthesia. 2017.
Cheung C.W., Peer Reviewer, Annals. 2017.
Cheung C.W., Peer Reviewer, BMC Anesthesiology. 2017.
Cheung C.W., Peer Reviewer, British Journal of Anaethesia. 2017.
Cheung C.W., Peer Reviewer, British Journal of Medicine and Medical Research. 2017.
Cheung C.W., Peer Reviewer, CNS Drugs. 2017.
Cheung C.W., Peer Reviewer, Case Reports in Medicine. 2017.
Cheung C.W., Peer Reviewer, Clinical. 2017.
Cheung C.W., Peer Reviewer, Clinical Neuropharmacology. 2017.
Cheung C.W., Peer Reviewer, Cochrane Review. 2017.
Cheung C.W., Peer Reviewer, Cosmetic and Investigational Dentistry. 2017.
Cheung C.W., Peer Reviewer, Current Medical Research and Opinion. 2017.
Cheung C.W., Peer Reviewer, Current Medicinal Chemistry. 2017.
Cheung C.W., Peer Reviewer, Disease of Oesophagus. 2017.
Cheung C.W., Peer Reviewer, Drug. 2017.
Cheung C.W., Peer Reviewer, European Neuropsychopharmacology. 2017.
Cheung C.W., Peer Reviewer, Expert Opinion on Investigational Drugs. 2017.
Cheung C.W., Peer Reviewer, Healthcare and Patient Safety. 2017.
Cheung C.W., Peer Reviewer, Hong Kong Medical Journal. 2017.
Cheung C.W., Peer Reviewer, IBRO Report. 2017.
Cheung C.W., Peer Reviewer, International Journal of Medicine and Medical Science. 2017.
Cheung C.W., Peer Reviewer, International Journal of Oral Science. 2017.
Cheung C.W., Peer Reviewer, International Journal of Oral and Maxillofacial Surgery. 2017.
Cheung C.W., Peer Reviewer, International Journal of Rheumatic Diseases. 2017.
Cheung C.W., Peer Reviewer, Journal of Anesthesia. 2017.
Cheung C.W., Peer Reviewer, Journal of Anesthesia and Clinical Research. 2017.
Cheung C.W., Peer Reviewer, Journal of Foot and Ankle. 2017.
Cheung C.W., Peer Reviewer, Journal of Oral and Facial Pain and Headache. 2017.
Cheung C.W., Peer Reviewer, Journal of Pain Research. 2017.
Cheung C.W., Peer Reviewer, Mayo Clinic Proceedings. 2017.
Cheung C.W., Peer Reviewer, Medicine. 2017.
Cheung C.W., Peer Reviewer, PLOS One. 2017.
Cheung C.W., Peer Reviewer, Pain Research and Treatment. 2017.
Cheung C.W., Peer Reviewer, Peptides. 2017.
Cheung C.W., Peer Reviewer, Pharmaceutics. 2017.
Cheung C.W., Peer Reviewer, Pharmacological Reports. 2017.
Cheung C.W., Peer Reviewer, Progress in Neurobiology. 2017.
Cheung C.W., Peer Reviewer, Spine Journal. 2017.
Cheung C.W., Peer Reviewer, The Tohoku Journal of Experimental Medicine. 2017.
Cheung C.W., Peer Reviewer, Trials. 2017.
Cheung C.W., Peer Reviewer, World Journal of Anesthesiology. 2017.
Cheung C.W., Peer Reviewer, World Journal of Clinical Cases. 2017.
Cheung C.W., Peer Reviewer, World Journal of Surgical Procedures. 2017.
Cheung C.W., Peer Reviewer, Yonsei Medical Journal. 2017.
Cheung C.W., Prescription drug monitoring programs needed to manage oioid use in Asia Pacific, Pain Practice. 2016, 16(5): E93.
Cheung C.W., Speaker, Organisation and Management of Pain Management Teams in Hong Kong, 第二次廣州國際麻醉科管理高峰論壇暨2016年廣東省醫院協會麻醉科管理專業委員會學術年會, 1-3 July 2016, Guangzhou, China. 2016.
Cheung C.W., Speaker, Prevalence of Neuropathic Pain among Chinese Adults, 24th Annual Meeting of Chinese Society of Anesthesiology, 25-28 August 2016, Guangzhou, China.. 2016.
Cheung C.W., Speaker, 兒童慢性疼痛管理, The 5th China-US (XiaoXiang) International Symposium of Pediatrics, 8-10 September 2016, Changsha, China. 2016.
Cheung C.W., Speaker. Acute Postoperative pain management or children, The 5th China US (XiaoXiang) International Symposium of Pediatrics. Changsha, China. 8th - 10th September 2016. 2016.
Cheung C.W., Speaker. Dexmedetomidine at session of acute pain pharmacology., 16th World Congress of Anaesthesiologists. Hong Kong. 29 August 2016. 2016.
Cheung C.W., Speaker. Interventional Pain Management at Queen Mary Hospital, Beijing, China. 8th - 11th December 2016. 2016 年協和麻醉大講堂暨羅愛倫教授行醫五十五周年學術研討會, 2016.
Cheung C.W., Speaker. Interventional pain management and its accreditation in Hong Kong, East Asia Interventional Pain Conference 2017, Kuala Lumpur, Malaysia. 13th - 14th January 2017. 2017.
Choi S.W. and Cheung C.W., Don't judge a book by its cover, don't judge a study by its abstract. Common statistical errors seen in medical papers, Anaesthesia. 2016, 71(7): 843-845.
Choi S.W., Lam D.M., Wong S.C.S., Shiu H.C., Wang X.M.A. and Cheung C.W., Effects of Single Nucleotide Polymorphisms on Surgical and Post-surgical Opioid Requirements - A Systematic Review and Meta-analysis, The Clinical Journal of Pain. 2017, 1.
Choi S.W. and Cheung C.W., The case of the misleading composite - one outcome is better than two, Anaesthesia. 2016, 71(9): 1101-1103.
FENG R., TIRRELL L., Cheung C.W. and Chung S.K., Deleted in Liver Cancer 2-deficiency Lead to more Severe Inflammatory Pain in Diabetic Mice with Altered Nerve Morphology and Activated RhoA/pERK/NF7, 21st Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2016.
Irwin M.G., Cheung C.W. and Wong G.T.C., Anaesthesia for ENT, dental, and maxillofacial surgery, Oxford textbook of Anaesthesia. 2017, 2.
Lu J., Yao X., LUO X., Wang Y., Chung S.K., Tang H., Cheung C.W., Wang X., Meng C. and Li Q., Monosialoganglioside 1 may alleviate neurotoxicity induced by propofol combined with remifentanil in neural stem cells, Neural Regeneration Research. 2017, 12: 945.
QIU Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intra-operative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Anaesthesia. 2016.
Qiu Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intraoperative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Survey of Anesthesiology. 2017, 61(1): 9-10.
Qiu Q., Sun L.T., Wang X.M.A., Tai W.L., GU P. and Cheung C.W., Signalling events underlying the analgesic effect of propofol in an inflammatory pain model, 16th World Congress on Pain. Yokohama, Japan. 26 September 2016 to 30 September 2016.
Sun L.T., GU P., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Analgesia induced by spinal cord stimulation following spinal cord injury associated with the activation of neuronal progenitor cells, INS 13th World Congress Neuromodulation: Technology Changing Lives. Edinburgh, Scotland, UK. 29th May 2017.
Sun L.T., GU P., Mitchell R., Fleetwood-Walker S., Joosten E. and Cheung C.W., Best Abstract Award, International Neuromodulation Society. International Neuromodulation Society, 2017, 74-75.
Sun L.T., Tai L., Qiu Q., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Endocannabinoid activation of CB1 receptors contributes to long-lasting reversal of neuropathic pain by repetitive spinal cord stimulation, European Journal of Pain. 2017, 21: 804-814.
Tian G., LUO X., Tang C., Cheng X., Chung S.K., Xia Z., Cheung C.W. and Guo Q., Astrocyte contributes to pain development via MMP2-JNK1/2 signaling in a mouse model of complex regional pain syndrome, Life Sciences. 2017, 170: 64-71.
Veniaminova E., Cespuglio R., Cheung C.W., Umriukhin A., Markova N., Shevtsova E., Lesch K.P., Anthony D.C. and Strekalova T., Autism-like behaviours and memory deficits accompany a high cholesterol diet in mice, Neural Plasticity. 2017, 2017: 9498247.
Wang L., Zhou M.T., Chen C.Y., Yin W., Wen D.X., Cheung C.W., Yang L.Q. and Yu W.F., Increased renal clearance of rocuronium compensates for chronic loss of bile excretion, via upregulation of Oatp2., Scientific Report. 2017, 7: 40438.
Wong K., Cheung C.W., So E., Huang B.M. and Leung Y.M., Palmitic acid-induced cytotoxicity in human alveolar A549 cells involved endoplasmic reticulum (Er) stress and reactive oxygen species production, World Congress of Anesthesiologists. 28 August to 2 September 2016.
Wong K., Tsai T.Y., Lou S.L. and Cheung C.W., The protective effects of arthenolide treatment in mouse cortical microvascular endothelial cells involved ca2+ clearance suppression by impairing plasmalemmal ca2+ pump activities and er stress, International Academy of Cardiology, 21st World Congress on Heart Disease, Boston, MA, USA, July 30 - Aug 1, 2016.
Zhao Y., Zheng Z.N., Cheung C.W., Zuo Z.Y. and Jin S.Q., Transfusion of plasma collected at late phase after preconditioning reduces myocardial infarct size induced by ischemia-reperfusion in rats in vivo, Chinese Medical Journal. 2017, 130(3): 303-308.
Zhao Y., Zheng Z.N., Cheung C.W., Zuo Z.Y. and Jin S.Q., Transfusion of preconditioned plasma reduced infarct size after myocardial ischemia-reperfusion and activated risk pathway in rats, World Congress of Anaesthesiologists. Hong Kong. 28 August 2016 to 2 September 2016.


Researcher : Choi SW

List of Research Outputs

Cheung C.W., Choi S.W., Wong S.C.S., Lee Y. and Irwin M.G., Changes in prevalence, outcomes and help seeking behaviour of chronic pain in an aging population over the last decade, Pain Practice. 2016.
Choi S.W. and Cheung C.W., Don't judge a book by its cover, don't judge a study by its abstract. Common statistical errors seen in medical papers, Anaesthesia. 2016, 71(7): 843-845.
Choi S.W., Lam D.M., Wong S.C.S., Shiu H.C., Wang X.M.A. and Cheung C.W., Effects of Single Nucleotide Polymorphisms on Surgical and Post-surgical Opioid Requirements - A Systematic Review and Meta-analysis, The Clinical Journal of Pain. 2017, 1.
Choi S.W. and Wong G.T.C., It's just a standard deviation!, Anaesthesia. 2016, 71: 969-971.
Choi S.W. and Cheung C.W., The case of the misleading composite - one outcome is better than two, Anaesthesia. 2016, 71(9): 1101-1103.
QIU Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intra-operative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Anaesthesia. 2016.
Qiu Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intraoperative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Survey of Anesthesiology. 2017, 61(1): 9-10.
Scott H.B., Choi S.W., Wong G.T.C. and Irwin M.G., The effect of remifentanil on propofol requirements to achieve loss of response to command vs. loss of response to pain, Anaesthesia. 2017, 72: 479-487.


Researcher : GU P

List of Research Outputs

Qiu Q., Sun L.T., Wang X.M.A., Tai W.L., GU P. and Cheung C.W., Signalling events underlying the analgesic effect of propofol in an inflammatory pain model, 16th World Congress on Pain. Yokohama, Japan. 26 September 2016 to 30 September 2016.
Sun L.T., GU P., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Analgesia induced by spinal cord stimulation following spinal cord injury associated with the activation of neuronal progenitor cells, INS 13th World Congress Neuromodulation: Technology Changing Lives. Edinburgh, Scotland, UK. 29th May 2017.
Sun L.T., GU P., Mitchell R., Fleetwood-Walker S., Joosten E. and Cheung C.W., Best Abstract Award, International Neuromodulation Society. International Neuromodulation Society, 2017, 74-75.


Researcher : Greenland KB

List of Research Outputs

Greenland K.B., Bradley W.P.L., Chapman G.A., Goulding G. and Irwin M.G., Emergency front-of-neck access: scalpel or cannula-and the parable of Buridan's ass+, British Journal of Anaesthesia. 2017, 118(6): 811-814.


Researcher : HUANG C

List of Research Outputs

Chang R.C.C., HUANG C. and Wong G.T.C., Impact of systemic inflammation on neuroinflammation, cognitive functions and phosphorylation of tau by laparotomy. Implication of postoperative cognitive dysfunctions to Alzheimer’s dementia., The 13th International Conference on Alzheimer’s & Parkinson’s Diseases 2017, Section B01.c Disease mechanisms, pathophysiology: Inflammation. 2017, 165.
HUANG C., LIU Y., Chu M.T., Chang R.C.C. and Wong G.T.C., The effect of varenicline on DNA damage and tau mislocalization in the cognitive impairment induced by laparotomy., International Alzheimer’s Disease Conference 2017. 39.
LIU Y., HUANG C., Chang R.C.C. and Wong G.T.C., Correlation between cognition enhancement and synaptic protein variation during prolonged sevoflurane exposure., International Alzheimer’s Disease Conference 2017. 42.


Researcher : Irwin MG

Project Title:A comparative study of hydroxyethyl starch (130/0.4) and gelatin on the immune response in paediatric scoliosis surgery
Investigator(s):Irwin MG, Wylie SJ
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:01/2009


Project Title:Radiofrequency therapy for chronic and cancer pain patient
Investigator(s):Irwin MG, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Effects of ketamine on the CGRP-CRLR ligand-receptor complex and pain signaling
Investigator(s):Irwin MG, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:05/2014


Project Title:The effect of over-expression of astrocytic ET-1 on Complex Regional Pain Syndrome I in a chronic post-ischaemia pain model.
Investigator(s):Irwin MG, Cheung CW, Wong SCS
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:06/2017


Project Title:Role of Brg1 in Sevoflurane Postconditioning Cardioprotection in Diabetes and Its Interplay with STAT3
Investigator(s):Irwin MG, Xia Z, Vanhoutte PMGR, Wong GTC
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2015


List of Research Outputs

Cai Y., PANG L., Tang E.H.C., Irwin M.G. and Xia Z., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis viaAkt-dependent enhancentment of iNOS expression, 14th Annual Meeting of the Society for Heart and Vascular Metabolism. 2016.
Cheung C.W., Choi S.W., Wong S.C.S., Lee Y. and Irwin M.G., Changes in prevalence, outcomes and help seeking behaviour of chronic pain in an aging population over the last decade, Pain Practice. 2016.
Greenland K.B., Bradley W.P.L., Chapman G.A., Goulding G. and Irwin M.G., Emergency front-of-neck access: scalpel or cannula-and the parable of Buridan's ass+, British Journal of Anaesthesia. 2017, 118(6): 811-814.
Irwin M.G., Cheung C.W. and Wong G.T.C., Anaesthesia for ENT, dental, and maxillofacial surgery, Oxford textbook of Anaesthesia. 2017, 2.
Irwin M.G., Annual Scientific Meeting, European Society of Anaesthesia, Geneva. 2017.
Irwin M.G., Annual Scientific Meeting, World Congress of anaesthesiologists, Hong Kong. . 2016.
Irwin M.G., Australia NZ College of Anaesthetists Annual Scientific Meeting, Mary Burnell Visitor. Brisbane.. 2017.
Irwin M.G., Editorial Board Member, Pain Research and Treatment, 2017.
Irwin M.G., Grant Reviewer, Hong Kong Research Grants Council. 2017.
Irwin M.G., Grants Reviewer, ANZCA Clinical Trails Network. 2017.
Irwin M.G., Grants Reviewer, Australian Academy of Health and Medical Sciences. 2017.
Irwin M.G., Grants Reviewer, Croatian Science Foundation . 2017.
Irwin M.G., Grants Reviewer, Health Services Research Committee/Health Care & Promotion Fund. 2017.
Irwin M.G., Grants Reviewer, National Institute of Academic Anaesthesia, UK. 2017.
Irwin M.G., Grants Reviewer, National Natural Science Foundation of China. 2017.
Irwin M.G., Grants Reviewer, SK Yee Medical Foundation. 2017.
Irwin M.G., Grants Reviewer, The Netherlands Organisation for Health Research and Development. 2017.
Irwin M.G., Guest editor, Supplement on Anesthesia for Vascular Surgery. 2016.
Irwin M.G., Journal Editor, Anaesthesia, Editorial Board Member. 2017.
Irwin M.G., Journal Editor, Editorial Board Member (Associate Editor), BioMed Central Perioperative Medicine. 2017.
Irwin M.G., Journal Editor, Editorial Board Member (Senior Editor Managing Reviews), Hong Kong Medical Journal. 2017.
Irwin M.G., Journal Editor, Editorial Board Member, Acta Anaesthesia Taiwanica. 2017.
Irwin M.G., Journal Editor, Editorial Board Member, Anaesthesia. 2017.
Irwin M.G., Journal Editor, Editorial Board Member, Anaesthesia and Intensive Care Medicine. 2017.
Irwin M.G., Journal Editor, Editorial Board Member, Expert Opinion on Pharmacology. 2017.
Irwin M.G., Journal Editor, Editorial Board Member, Journal of International Medical Research. 2017.
Irwin M.G., Meeting, South China Congress of Cardiology . 2017.
Irwin M.G., Peer Reviewer, Anaesthesia. 2017.
Irwin M.G., Peer Reviewer, Anaesthesia and Intensive Care. 2017.
Irwin M.G., Peer Reviewer, Anesthesia and Analgesia. 2017.
Irwin M.G., Peer Reviewer, Anesthesiology. 2017.
Irwin M.G., Peer Reviewer, Asean Journal of Anaesthesiology. 2017.
Irwin M.G., Peer Reviewer, British Journal of Anaesthesia. 2017.
Irwin M.G., Peer Reviewer, British Journal of Pharmacology. 2017.
Irwin M.G., Peer Reviewer, British Journal of Surgery. 2017.
Irwin M.G., Peer Reviewer, Canadian Journal of Anaesthesia. 2017.
Irwin M.G., Peer Reviewer, Canadian Journal of Physiology & Pharmacology. 2017.
Irwin M.G., Peer Reviewer, Croation Science Foundation. 2016.
Irwin M.G., Peer Reviewer, Diabetes. 2017.
Irwin M.G., Peer Reviewer, European Journal of Pharmacology. 2017.
Irwin M.G., Peer Reviewer, Expert Opinion on Investigational Drugs. 2017.
Irwin M.G., Peer Reviewer, International Immunopharmacology. 2017.
Irwin M.G., Peer Reviewer, Journal of Cardiothoracic and Vascular Anesthesia. 2017.
Irwin M.G., Peer Reviewer, Journal of Maxillofacial Surgery. 2017.
Irwin M.G., Peer Reviewer, Journal of Molecular and Cellular Cardiology. 2017.
Irwin M.G., Peer Reviewer, Journal of Neuroscience Methods. 2017.
Irwin M.G., Peer Reviewer, Journal of Paediatrics, Obstetrics and Gynaecology. 2017.
Irwin M.G., Peer Reviewer, Journal of Pharmaceutical & Biomedical Analysis. 2017.
Irwin M.G., Peer Reviewer, Journal of clinical Anaesthesia. 2017.
Irwin M.G., Peer Reviewer, Lancet. 2017.
Irwin M.G., Peer Reviewer, Medical Science Monitor. 2017.
Irwin M.G., Peer Reviewer, Oncotraget. 2017.
Irwin M.G., Peer Reviewer, Surgical Practice. 2017.
QIU Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intra-operative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Anaesthesia. 2016.
Qiu Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intraoperative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Survey of Anesthesiology. 2017, 61(1): 9-10.
Scott H.B., Choi S.W., Wong G.T.C. and Irwin M.G., The effect of remifentanil on propofol requirements to achieve loss of response to command vs. loss of response to pain, Anaesthesia. 2017, 72: 479-487.
She W.H., Cheung T.T., Jenkins C.R. and Irwin M.G., Clinical applications of high-intensity focused ultrasound, Hong Kong Medical Journal. 2016, 22(4): 382-392.
Wong G.T.C., Lee E.Y.P. and Irwin M.G., Contrast induced nephropathy in vascular surgery, British Journal of Anaesthesia. 2016, 117: ii63-ii73.
Xia Z., Li H. and Irwin M.G., Myocardial ischaemia reperfusion injury: the challenge of translating ischaemic and anaesthetic protection from animal models to humans, Br J Anaesth. 2016.


Researcher : Jenkins CR

List of Research Outputs

She W.H., Cheung T.T., Jenkins C.R. and Irwin M.G., Clinical applications of high-intensity focused ultrasound, Hong Kong Medical Journal. 2016, 22(4): 382-392.


Researcher : Joosten EAJ

List of Research Outputs

Sun L.T., GU P., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Analgesia induced by spinal cord stimulation following spinal cord injury associated with the activation of neuronal progenitor cells, INS 13th World Congress Neuromodulation: Technology Changing Lives. Edinburgh, Scotland, UK. 29th May 2017.
Sun L.T., Tai L., Qiu Q., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Endocannabinoid activation of CB1 receptors contributes to long-lasting reversal of neuropathic pain by repetitive spinal cord stimulation, European Journal of Pain. 2017, 21: 804-814.


Researcher : LI H

List of Research Outputs

Ge M., Yao W., Yuan D., Zhou S., Chen X., Zhang Y., Li H., Xia Z. and Hei Z., Brg1-mediated Nrf2/HO-1 pathway activation alleviates hepatic ischemia-reperfusion injury. , Cell Death Dis. 2017, 8(6): e2841.
PANG L., Cai Y., Tang E.H.C., YAN D., Li H., IRWIN M.G., MA H., Xia Z. and RAMOJI K., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis via Akt-dependent enhancentment of iNOS expression, Oxidative Medicine and Cellular Longevity. 2016.
Wang S., WANG C., Yan F., Wang T., He Y., Li H., Xia Z. and Zhang Z., N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy., Mediators Inflamm. 2017, 2017: 9257291.
Wu Q., Wang T., Chen S., Zhou Q., Li H., Hu N., Feng Y., Dong H., Yao S. and Xia Z., Cardiac protective effects of remote ischaemic preconditioning in children undergoing tetralogy of fallot repair surgery: a randomized controlled trial., Eur Heart J. 2017.
Xia Z., Li H. and Irwin M.G., Myocardial ischaemia reperfusion injury: the challenge of translating ischaemic and anaesthetic protection from animal models to humans, Br J Anaesth. 2016.
Zhou M., Bao Y., LI H., PAN Y., SHU L., Xia Z., Wu D., Vanhoutte P.M.G.R., Xu A., Jia W. and Hoo R.L.C., Deficiency of adipocyte fatty-acid-binding protein alleviates myocardial ischaemia/reperfusion injury and diabetes-induced cardiac dysfunction., Clinical Science. 2016.


Researcher : LIU Y

List of Research Outputs

HUANG C., LIU Y., Chu M.T., Chang R.C.C. and Wong G.T.C., The effect of varenicline on DNA damage and tau mislocalization in the cognitive impairment induced by laparotomy., International Alzheimer’s Disease Conference 2017. 39.
LIU Y., HUANG C., Chang R.C.C. and Wong G.T.C., Correlation between cognition enhancement and synaptic protein variation during prolonged sevoflurane exposure., International Alzheimer’s Disease Conference 2017. 42.


Researcher : LUO X

List of Research Outputs

Lu J., Yao X., LUO X., Wang Y., Chung S.K., Tang H., Cheung C.W., Wang X., Meng C. and Li Q., Monosialoganglioside 1 may alleviate neurotoxicity induced by propofol combined with remifentanil in neural stem cells, Neural Regeneration Research. 2017, 12: 945.
Tian G., LUO X., Tang C., Cheng X., Chung S.K., Xia Z., Cheung C.W. and Guo Q., Astrocyte contributes to pain development via MMP2-JNK1/2 signaling in a mouse model of complex regional pain syndrome, Life Sciences. 2017, 170: 64-71.


Researcher : Lee Y

List of Research Outputs

Cheung C.W., Choi S.W., Wong S.C.S., Lee Y. and Irwin M.G., Changes in prevalence, outcomes and help seeking behaviour of chronic pain in an aging population over the last decade, Pain Practice. 2016.


Researcher : Li H

List of Research Outputs

Ge M., Yao W., Yuan D., Zhou S., Chen X., Zhang Y., Li H., Xia Z. and Hei Z., Brg1-mediated Nrf2/HO-1 pathway activation alleviates hepatic ischemia-reperfusion injury. , Cell Death Dis. 2017, 8(6): e2841.
PANG L., Cai Y., Tang E.H.C., YAN D., Li H., IRWIN M.G., MA H., Xia Z. and RAMOJI K., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis via Akt-dependent enhancentment of iNOS expression, Oxidative Medicine and Cellular Longevity. 2016.
Wang S., WANG C., Yan F., Wang T., He Y., Li H., Xia Z. and Zhang Z., N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy., Mediators Inflamm. 2017, 2017: 9257291.
Wu Q., Wang T., Chen S., Zhou Q., Li H., Hu N., Feng Y., Dong H., Yao S. and Xia Z., Cardiac protective effects of remote ischaemic preconditioning in children undergoing tetralogy of fallot repair surgery: a randomized controlled trial., Eur Heart J. 2017.
Xia Z., Li H. and Irwin M.G., Myocardial ischaemia reperfusion injury: the challenge of translating ischaemic and anaesthetic protection from animal models to humans, Br J Anaesth. 2016.
Zhou M., Bao Y., LI H., PAN Y., SHU L., Xia Z., Wu D., Vanhoutte P.M.G.R., Xu A., Jia W. and Hoo R.L.C., Deficiency of adipocyte fatty-acid-binding protein alleviates myocardial ischaemia/reperfusion injury and diabetes-induced cardiac dysfunction., Clinical Science. 2016.


Researcher : Ng JKF

Project Title:The role of endothelial arginine, arginase and nitric oxide on dexmedetomidine induced vascular contraction
Investigator(s):Ng KFJ, Leung SWS
Department:Anaesthesiology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2012




Researcher : Ng KFJ

Project Title:The role of endothelial arginine, arginase and nitric oxide on dexmedetomidine induced vascular contraction
Investigator(s):Ng KFJ, Leung SWS
Department:Anaesthesiology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2012




Researcher : QIU Q

List of Research Outputs

Cheung C.W., Wong S.C.S., Qiu Q. and Wang X.M.A., Oral oxycodone for acute postoperative pain: a narrative review of clinical trails, Pain Physician. 2017, 20(2S): SE33-SE52.
QIU Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intra-operative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Anaesthesia. 2016.
Qiu Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intraoperative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Survey of Anesthesiology. 2017, 61(1): 9-10.
Qiu Q., Sun L.T., Wang X.M.A., Tai W.L., GU P. and Cheung C.W., Signalling events underlying the analgesic effect of propofol in an inflammatory pain model, 16th World Congress on Pain. Yokohama, Japan. 26 September 2016 to 30 September 2016.
Sun L.T., Tai L., Qiu Q., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Endocannabinoid activation of CB1 receptors contributes to long-lasting reversal of neuropathic pain by repetitive spinal cord stimulation, European Journal of Pain. 2017, 21: 804-814.


Researcher : Qiu Q

List of Research Outputs

Cheung C.W., Wong S.C.S., Qiu Q. and Wang X.M.A., Oral oxycodone for acute postoperative pain: a narrative review of clinical trails, Pain Physician. 2017, 20(2S): SE33-SE52.
QIU Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intra-operative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Anaesthesia. 2016.
Qiu Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intraoperative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Survey of Anesthesiology. 2017, 61(1): 9-10.
Qiu Q., Sun L.T., Wang X.M.A., Tai W.L., GU P. and Cheung C.W., Signalling events underlying the analgesic effect of propofol in an inflammatory pain model, 16th World Congress on Pain. Yokohama, Japan. 26 September 2016 to 30 September 2016.
Sun L.T., Tai L., Qiu Q., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Endocannabinoid activation of CB1 receptors contributes to long-lasting reversal of neuropathic pain by repetitive spinal cord stimulation, European Journal of Pain. 2017, 21: 804-814.


Researcher : Rodrigo MRC

Project Title:4th South Asian Confederation of Anaesthesiologists Congress Anaesthesia for Orthognathic Surgery
Investigator(s):Rodrigo MRC
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/1999


Project Title:The Association of Dental Anaesthetists 25th Anniversary Summer Scientific Meeting Patient Controlled Sedation with Propolfol
Investigator(s):Rodrigo MRC
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2002




Researcher : Scott HB

List of Research Outputs

Scott H.B., Choi S.W., Wong G.T.C. and Irwin M.G., The effect of remifentanil on propofol requirements to achieve loss of response to command vs. loss of response to pain, Anaesthesia. 2017, 72: 479-487.


Researcher : Shiu HC

List of Research Outputs

Choi S.W., Lam D.M., Wong S.C.S., Shiu H.C., Wang X.M.A. and Cheung C.W., Effects of Single Nucleotide Polymorphisms on Surgical and Post-surgical Opioid Requirements - A Systematic Review and Meta-analysis, The Clinical Journal of Pain. 2017, 1.


Researcher : Sun LT

Project Title:International Neuromodulation Society 13th World Congress ; Analgesia induced by spinal cord stimulation following spinal cord injury is associated with the activation of neuronal progenitor cells
Investigator(s):Sun LT
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2017
Completion Date:06/2017


List of Research Outputs

Qiu Q., Sun L.T., Wang X.M.A., Tai W.L., GU P. and Cheung C.W., Signalling events underlying the analgesic effect of propofol in an inflammatory pain model, 16th World Congress on Pain. Yokohama, Japan. 26 September 2016 to 30 September 2016.
Sun L.T., GU P., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Analgesia induced by spinal cord stimulation following spinal cord injury associated with the activation of neuronal progenitor cells, INS 13th World Congress Neuromodulation: Technology Changing Lives. Edinburgh, Scotland, UK. 29th May 2017.
Sun L.T., GU P., Mitchell R., Fleetwood-Walker S., Joosten E. and Cheung C.W., Best Abstract Award, International Neuromodulation Society. International Neuromodulation Society, 2017, 74-75.
Sun L.T., Tai L., Qiu Q., Mitchell R., Fleetwood-Walker S., Joosten E.A.J. and Cheung C.W., Endocannabinoid activation of CB1 receptors contributes to long-lasting reversal of neuropathic pain by repetitive spinal cord stimulation, European Journal of Pain. 2017, 21: 804-814.


Researcher : Tai WL

List of Research Outputs

Qiu Q., Sun L.T., Wang X.M.A., Tai W.L., GU P. and Cheung C.W., Signalling events underlying the analgesic effect of propofol in an inflammatory pain model, 16th World Congress on Pain. Yokohama, Japan. 26 September 2016 to 30 September 2016.


Researcher : Tang C

List of Research Outputs

Tian G., LUO X., Tang C., Cheng X., Chung S.K., Xia Z., Cheung C.W. and Guo Q., Astrocyte contributes to pain development via MMP2-JNK1/2 signaling in a mouse model of complex regional pain syndrome, Life Sciences. 2017, 170: 64-71.


Researcher : WANG C

List of Research Outputs

Wang S., WANG C., Yan F., Wang T., He Y., Li H., Xia Z. and Zhang Z., N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy., Mediators Inflamm. 2017, 2017: 9257291.


Researcher : Wang XMA

List of Research Outputs

Cheung C.W., Wong S.C.S., Qiu Q. and Wang X.M.A., Oral oxycodone for acute postoperative pain: a narrative review of clinical trails, Pain Physician. 2017, 20(2S): SE33-SE52.
Choi S.W., Lam D.M., Wong S.C.S., Shiu H.C., Wang X.M.A. and Cheung C.W., Effects of Single Nucleotide Polymorphisms on Surgical and Post-surgical Opioid Requirements - A Systematic Review and Meta-analysis, The Clinical Journal of Pain. 2017, 1.
Qiu Q., Sun L.T., Wang X.M.A., Tai W.L., GU P. and Cheung C.W., Signalling events underlying the analgesic effect of propofol in an inflammatory pain model, 16th World Congress on Pain. Yokohama, Japan. 26 September 2016 to 30 September 2016.
Tiwari A.F.Y., Lao L., Wang X.M.A., Cheung S.T., So M.K., Yu D.S., Lum T.Y.S., Yuk F.H.Y.K., Yeung J.W.F. and Zhang Z., Self-administered acupressure for symptom management among Chinese family caregivers with caregiver stress: a randomized, wait-list controlled trial, BMC Complementary and Alternative Medicine . 2016, 16.


Researcher : Wong GTC

Project Title:The cardiac preconditioning effect of surgery patients
Investigator(s):Wong GTC, Irwin MG, Hiong YT, Das SR
Department:Anaesthesiology
Source(s) of Funding:Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme
Start Date:10/2007


Project Title:The impact of preoperative and postoperative haemoglobin level on rehabilitation duration in fracture hip patients
Investigator(s):Wong GTC, Leung FKL
Department:Anaesthesiology
Source(s) of Funding:AOTrauma
Start Date:09/2014


Project Title:The evaluation of insulin resistance as a precipitating factor for postoperative cognitive dysfunction
Investigator(s):Wong GTC, Chang RCC
Department:Anaesthesiology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2015
Completion Date:04/2017


Project Title:Forced resistant exercise preconditioning reduces postoperative cognitive dysfunction in mice
Investigator(s):Wong GTC, Chang RCC
Department:Anaesthesiology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2016


Project Title:The role of surgery induced type 1 interferon on blood brain barrier dysfunction and postoperative cognitive dysfunction
Investigator(s):Wong GTC, Chang RCC
Department:Anaesthesiology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2017


List of Research Outputs

Chang R.C.C., HUANG C. and Wong G.T.C., Impact of systemic inflammation on neuroinflammation, cognitive functions and phosphorylation of tau by laparotomy. Implication of postoperative cognitive dysfunctions to Alzheimer’s dementia., The 13th International Conference on Alzheimer’s & Parkinson’s Diseases 2017, Section B01.c Disease mechanisms, pathophysiology: Inflammation. 2017, 165.
Choi S.W. and Wong G.T.C., It's just a standard deviation!, Anaesthesia. 2016, 71: 969-971.
Chu M.T., Ho Y.S., Wong G.T.C. and Chang R.C.C., Aerobic training increased FGF21 expression and attenuated cognition in Alzheimer’s disease mice. , International Alzheimer’s Disease Conference 2017. 42.
HUANG C., LIU Y., Chu M.T., Chang R.C.C. and Wong G.T.C., The effect of varenicline on DNA damage and tau mislocalization in the cognitive impairment induced by laparotomy., International Alzheimer’s Disease Conference 2017. 39.
Irwin M.G., Cheung C.W. and Wong G.T.C., Anaesthesia for ENT, dental, and maxillofacial surgery, Oxford textbook of Anaesthesia. 2017, 2.
Kwan S.K.J., Wong G.T.C. and Tse M.A., Benefit to the older people who train and work as exercise coaches (PI, $50K), Queen Mary Hospital Training & Research Assistance Scheme. 2017.
LIU Y., HUANG C., Chang R.C.C. and Wong G.T.C., Correlation between cognition enhancement and synaptic protein variation during prolonged sevoflurane exposure., International Alzheimer’s Disease Conference 2017. 42.
Scott H.B., Choi S.W., Wong G.T.C. and Irwin M.G., The effect of remifentanil on propofol requirements to achieve loss of response to command vs. loss of response to pain, Anaesthesia. 2017, 72: 479-487.
Wong G.T.C., "Who monitors the monitors?" An overlooked parameter? Symposium on Emerging Trends in Intensive Care Medicine with Noninvasive Monitoring, 4th Annual SG ANZICS Intensive Care Forum Singapore. 2017.
Wong G.T.C., Anesthesia on cognitive function, The 2nd International Conference on Anesthesia and Airway Management 2016 Phuket. 2016.
Wong G.T.C., Lee E.Y.P. and Irwin M.G., Contrast induced nephropathy in vascular surgery, British Journal of Anaesthesia. 2016, 117: ii63-ii73.
Wong G.T.C., Delirium, Asia Anaesthesia Forum, National Heart Institute of Malaysia 17th & 18th February 2017. 2017.
Wong G.T.C., Objective determination of fitness, The First Hong Kong Evidence Based Peri-Operative Medicine Symposium: EBPOM 2017. 2017.
Wong G.T.C., Post operative cognitive dysfunction and delirium, National CME Meeting of the Shenzhen Society of Anaesthesiologist,Shenzhen Hospital of Southern Medical University. 2017.
Wong G.T.C., Rapid and quality recovery after surgery: Role of Anesthesiologist, 2nd International Conference of Anesthesia and Airway Management 2016, Phuket, Thailand. 2016.
Wong G.T.C., Reviewer for manuscript number 1920427 Open Journal of Anesthesiology, 2016.
Wong G.T.C., Reviewer for manuscript number PERI-D-16-00049 for Preoperative Medicine, 2017.
Wong G.T.C., Reviewer of Manuscript No HKMJ-6090 for the Hong Kong Medical Journal, 2016.
Wong G.T.C., TIVA in Day Surgery, Malaysian Society of Anesthesiologists and College of Anesthesiologists, AMM Annual Scientific Congress 2017. 2017.
YANG C., Wong G.T.C. and Kwan S.K.J., Event related potential during prospective memory task may predict cognitive function in subjective cognitive decline, 12th International Symposium on Healthy Aging. 2017.
YANG C., LI J., Wong G.T.C. and Kwan S.K.J., Event-related potential using task-based electroencephalogram may differentiate between mild cognitive impairment and normal controls, 22nd Medical Research Conference (HKU). 2017.
YANG C., Wong G.T.C. and Kwan S.K.J., The behavioral performance and event-related potential components of the go/no-go task from healthy elders to mild cognitive impairment, 12th International Symposium on Healthy Aging. 2017.


Researcher : Wong K

List of Research Outputs

Wong K., Cheung C.W., So E., Huang B.M. and Leung Y.M., Palmitic acid-induced cytotoxicity in human alveolar A549 cells involved endoplasmic reticulum (Er) stress and reactive oxygen species production, World Congress of Anesthesiologists. 28 August to 2 September 2016.
Wong K., Tsai T.Y., Lou S.L. and Cheung C.W., The protective effects of arthenolide treatment in mouse cortical microvascular endothelial cells involved ca2+ clearance suppression by impairing plasmalemmal ca2+ pump activities and er stress, International Academy of Cardiology, 21st World Congress on Heart Disease, Boston, MA, USA, July 30 - Aug 1, 2016.


Researcher : Wong SCS

Project Title:Intrathecal administration of RhoA, ROCK and ERK inhibitors reduces thermal and inflammatory hyperalgesia in DLC2-/- (knockout) mice
Investigator(s):Wong SCS, Chung SK, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:04/2015


List of Research Outputs

Cheung C.W., Choi S.W., Wong S.C.S., Lee Y. and Irwin M.G., Changes in prevalence, outcomes and help seeking behaviour of chronic pain in an aging population over the last decade, Pain Practice. 2016.
Cheung C.W., Wong S.C.S., Qiu Q. and Wang X.M.A., Oral oxycodone for acute postoperative pain: a narrative review of clinical trails, Pain Physician. 2017, 20(2S): SE33-SE52.
Choi S.W., Lam D.M., Wong S.C.S., Shiu H.C., Wang X.M.A. and Cheung C.W., Effects of Single Nucleotide Polymorphisms on Surgical and Post-surgical Opioid Requirements - A Systematic Review and Meta-analysis, The Clinical Journal of Pain. 2017, 1.
QIU Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intra-operative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Anaesthesia. 2016.
Qiu Q., Choi S.W., Wong S.C.S., Irwin M.G. and Cheung C.W., Effects of intraoperative maintenance of general anaesthesia with propofol on postoperative pain outcomes - a systematic review and meta-analysis, Survey of Anesthesiology. 2017, 61(1): 9-10.
Wong S.C.S., Oral opioids for acute postoperative pain: A review of clinical trials, 2017 Integrated Care Conference on Cancer Supportive Care and Enhancing Recovery after Orthopaedic Surgery. 2017.


Researcher : Wong TM

Project Title:First Asia-Pacific Opioid Symposium Cardioprotective Effects of K-Opioids
Investigator(s):Wong TM
Department:Physiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2000


Project Title:Outstanding Research Student Supervisor Award 2001-2002
Investigator(s):Wong TM
Department:Anaesthesiology
Source(s) of Funding:Outstanding Research Student Supervisor Award
Start Date:06/2002


Project Title:XVIII World Congress International Society for Heart Research in Conjunction with 52nd Annual Scientific Meeting of the Cardiac Society of Australia & New Zealand Delayed Cardioprotection of Kappa Opioid Receptor Stimulation in Normal and Diabetic Rats - Roles of Heat Shock Protein 70 and Intracellular Ca2+
Investigator(s):Wong TM
Department:Physiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2004


Project Title:CSANZ 2006 Annual Scientific Meeting Heat Shock Protein 70, Calcium Regulation and Cardiac Survival
Investigator(s):Wong TM
Department:Physiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2006




Researcher : Xia Z

Project Title:Nitrate tolerance compromises propofol protection of the endothelium against inflammation: The role of PKC-beta2 and NADPH oxidase interaction
Investigator(s):Xia Z
Department:Anaesthesiology
Source(s) of Funding:SCA Research Starter and MidCareer Grants
Start Date:07/2008


Project Title:The role of FoxO1 in diabetic heart susceptibility to ischemia/reperfusion injury and sensitivity to ischemic postconditioning and its interplay with adiponectin
Investigator(s):Xia Z, Vanhoutte PMGR, Xu A, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2014


Project Title:Experimental Biology 2015; Dexmedetomidine enhances cerebral cortex GIRK1 protein expression and attenuates Acute Postoperative Pain in rats.
Investigator(s):Xia Z
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2015


Project Title:Sevoflurance cardiopulmonary protection and mechanism
Investigator(s):Xia Z
Department:Anaesthesiology
Source(s) of Funding:The First Hospital of Jilin University
Start Date:08/2015


Project Title:PKCß2 over-activation reduces cardiac tolerance to ischemia-reperfusion injury in diabetic rodents by downregulating caveolin-3 and modulating cardiomyocyte autophagy
Investigator(s):Xia Z, Xu A, Vanhoutte PMGR, Wang JJ, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2015


Project Title:PKCε over-activation by down-regulating caveolin-3 compromises adiponectin-mediated ischemic postconditioning cardioprotection in diabetes
Investigator(s):Xia Z, Irwin MG, Vanhoutte PMGR, Xu A
Department:Anaesthesiology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016


Project Title:PKC-ϵ facilitates adiponectin to restore diabetic heart responsiveness to ischemic postconditioning: The importance of PKC-ϵ/Cav3 association.
Investigator(s):Xia Z, Vanhoutte PMGR, Xu A, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2017


Project Title:Brg1 by down-regulating lncCNIF-mediated necroptosis restores sevoflurane postconditioning cardioprotection in diabetes
Investigator(s):Xia Z, Xu A, Irwin MG, Li H
Department:Anaesthesiology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


Project Title:2017 年中国研究型医院学会麻醉专业委员会学术年会; The Clinical Application of Remote Ischemic Preconditioning and Postconditioning in Cardiac Protection: The Challenges and Promises.
Investigator(s):Xia Z
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2017
Completion Date:07/2017


List of Research Outputs

CHENG Y., LUO D., Xia Z., Tse H.F., Li X.C. and Rong J., In Vivo Cardioprotective Effects and Pharmacokinetic Profile of N-Propyl Caffeamide Against Ischemia Reperfusion Injury, Archivum Immunologiae et Therapiae Experimentalis. 2016.
Cai Y., PANG L., Tang E.H.C., Irwin M.G. and Xia Z., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis viaAkt-dependent enhancentment of iNOS expression, 14th Annual Meeting of the Society for Heart and Vascular Metabolism. 2016.
Ge M., Yao W., Yuan D., Zhou S., Chen X., Zhang Y., Li H., Xia Z. and Hei Z., Brg1-mediated Nrf2/HO-1 pathway activation alleviates hepatic ischemia-reperfusion injury. , Cell Death Dis. 2017, 8(6): e2841.
Hoo R.L.C., Zhou M., PAN Y., SHU L., Sung Y.J.C., Zhong D., Xia Z., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein (A-FABP) is a potential mediator of heart dysfunction and failure related to obesity, The 11th International Diabetes Federation Western Pacific Region (IDF-WPR) Congress and the 8th Scientific Meeting of the Asian Association for the Study of Diabetes (AASD). 2016.
Li J., Li J., Liu Z., Yan B., Pan Z., Huang D., Liang Q., Ying D., Xu F., Yao H., Wang P., Kocher J.A., Xia Z., Sham P.C., Liu J.S. and Wang J.J., cepip: context-dependent epigenomic weighting for prioritization of regulatory variants and disease-associated genes, Genome Biol. 2017, 18(1): 52.
Li S., Zeng J., Wan X., Yao Y., Zhao N., Yu Y., Yu C. and Xia Z., Enhancement of spinal dorsal horn neuron NMDA receptor phosphorylation as the mechanism of remifentanil induced hyperalgesia: Roles of PKC and CaMKII., Molecular Pain. 2017.
Liu Y., Baumgardt S.L., Fang J., Shi Y., Qiao S., Bosnjak Z.J., Vásquez-Vivar J., Xia Z., Warltier D.C. and Kersten J., Transgenic overexpression of GTP cyclohydrolase 1 in cardiomyocytes ameliorates post-infarction cardiac remodeling., Scientific Reports. 2017, 7(1): 3093.
PANG L., Cai Y., Tang E.H.C., YAN D., Li H., IRWIN M.G., MA H., Xia Z. and RAMOJI K., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis via Akt-dependent enhancentment of iNOS expression, Oxidative Medicine and Cellular Longevity. 2016.
Qi D., Xia Z. and Zhuang Z., Metabolic Mechanisms and Potential Therapies of Diabetic Cardiac Complications., J Diabetes Res. 2017, 2017: 5130496.
Su W., Zhang Y., Zhang Q., Xu J., Zhan L., Zhu Q., Lian Q., Liu H., Xia Z.Y., Xia Z. and Lei S., N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats., Cardiovasc Diabetol. 2016, 15(1): 146.
Tian G., LUO X., Tang C., Cheng X., Chung S.K., Xia Z., Cheung C.W. and Guo Q., Astrocyte contributes to pain development via MMP2-JNK1/2 signaling in a mouse model of complex regional pain syndrome, Life Sciences. 2017, 170: 64-71.
Wang S., WANG C., Yan F., Wang T., He Y., Li H., Xia Z. and Zhang Z., N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy., Mediators Inflamm. 2017, 2017: 9257291.
Wu Q., Wang T., Chen S., Zhou Q., Li H., Hu N., Feng Y., Dong H., Yao S. and Xia Z., Cardiac protective effects of remote ischaemic preconditioning in children undergoing tetralogy of fallot repair surgery: a randomized controlled trial., Eur Heart J. 2017.
Xia Z., Ischemic preconditioning cardioprotection: Remote distance vs. Remote time, 2016 Annual Meeting on Continuing Education of Anesthesiology of Anhui Province. 2016.
Xia Z., Li H. and Irwin M.G., Myocardial ischaemia reperfusion injury: the challenge of translating ischaemic and anaesthetic protection from animal models to humans, Br J Anaesth. 2016.
Xia Z., Peer Reviewer for Journal, Can J Anesthesia. 2016.
Xia Z., Recognition as core member consulting medical scientist delegate to Guizhou Provincial Development, GuiZhou Provincial Government. 2016.
Xia Z., Recognition of as leading contributing medical scientist to Guizhou Province, China, Guizhou Provincial Government. 2016.
Xia Z., Recognition of outstanding contribution as medical scientist to Guizhou Province, Guizhou Provincial Government. 2016.
Xia Z., Remote Ischemic Preconditioning In Cardioprotection: Remote time or distance, 2016 International Basic and Clinical Research Forum of Anesthesia. 2016.
Xia Z., Remote Ischemic Preconditioning: From Heart to Brain/Remote Distance and Time, 2016 Hunan Provincial Anesthesiology Society Annual Meeting. 2016.
Xia Z., Remote Ischemic Preconditioning: From Heart to Brain/Remote Distance and Time, 2016 South China University Anesthesia Forum. 2016.
Xia Z., Remote Ischemic preconditioning: The Challenge of Its Clinical Application, 2016 Chinese Society of Anesthesiologists Annual Meeting. 2016.
Xia Z., Research Design, Writing up and Submission of High Quality Medical Paper, 2016 Fujian Provincial Anesthesia Forum. 2016.
Xia Z., Research design and the writing up of high quality of medical research paper, The 2nd Guangzhou International Anesthesiology Forum. 2016.
Yang L., Xie P., Wu J., Yu J., Yu T., Wang H., Wang J., Xia Z. and Zheng H., Sevoflurane postconditioning improves myocardial mitochondrial respiratory function and reduces myocardial ischemia-reperfusion injury by up-regulating HIF-1., Am J Transl Res. 2016, 8(10): 4415-4424.
Yu J., Wu J., Xie P., Maimaitili Y., Wang J., Xia Z., Gao F., Zhang X. and Zheng H., Sevoflurane postconditioning attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring mitochondrial morphology., Peer J. 2016, 4: e2659.
Zhou B., Lei S., Xue R., Leng Y., Xia Z. and Xia Z.Y., DJ-1 overexpression restores ischaemic post-conditioning-mediated cardioprotection in diabetic rats: role of autophagy., Clin Sci (Lond). 2017, 131(11): 1161-1178.
Zhou M., Bao Y., LI H., PAN Y., SHU L., Xia Z., Wu D., Vanhoutte P.M.G.R., Xu A., Jia W. and Hoo R.L.C., Deficiency of adipocyte fatty-acid-binding protein alleviates myocardial ischaemia/reperfusion injury and diabetes-induced cardiac dysfunction., Clinical Science. 2016.


Researcher : Yao W

List of Research Outputs

Ge M., Yao W., Yuan D., Zhou S., Chen X., Zhang Y., Li H., Xia Z. and Hei Z., Brg1-mediated Nrf2/HO-1 pathway activation alleviates hepatic ischemia-reperfusion injury. , Cell Death Dis. 2017, 8(6): e2841.


Researcher : Yuen VMY

Project Title:Comparison of oral chloral hydrate and intranasal dexmedetomidine for sedation in children undergoing computerised tomography in Queen Mary Hospital
Investigator(s):Yuen VMY, Hui TWC, Wong ICK, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:03/2014
Completion Date:06/2017




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