DEPT OF OPHTHALMOLOGY



Researcher : Chan JCH

Project Title:The feasibility of screening for diabetic retinopathy in private practice Hong Kong
Investigator(s):Chan JCH, McGhee S
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2015


Project Title:Trabeculectomy with EX-PRESS and ologen implants and Mitomycin-C in Primary Open Angle Glaucoma and Ocular Hypertension – A Pilot Study
Investigator(s):Chan JCH, Choy NKB, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research for New Staff
Start Date:06/2016


Project Title:Canadian Ophthalmological Society Annual Meeting and Exhibition; Macular Optical Coherence Tomography Improves Cost-Effectiveness of Screening for Diabetic Macular Edema
Investigator(s):Chan JCH
Department:Ophthalmology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2018
Completion Date:06/2018


Project Title:Introduction of Micropulse Laser Transscleral Cyclophotocoagulation as a Non-Surgical Treatment Option for Glaucoma Patients in Hong Kong West Cluster
Investigator(s):Chan JCH, Choy NKB
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:06/2018


List of Research Outputs

Chan J.C.H., Diabetic Eye Disease, Update on Diabetes Management 2017. 2017.
Chan J.C.H., Diabetic retinopathy screening – Hong kong’s experience, 糖尿病視網膜病變(糖網病)篩查 - 香港的經驗, The 6th Cross-Strait Four Regions Ophthalmologic Symposium. 澳門第六屆兩岸四地眼科學術研討會, 2017.
Chan J.C.H. and Wong K.W.J., Minimally Invasive Glaucoma Surgery, In: MOK Chun-on, CHAN Chi-fung Godfrey, CHAN Chi-kuen KING Wing-Keung Walter, LO See-kit Raymond, The Hong Kong Medical Diary. 香港醫訊, 2018.
Shum J.W.H., Lam W.W.T., Choy N.K.B., Chan J.C.H., Ho W.L. and Lai J.S.M., Development and pilot-testing of patient decision aid for use among Chinese patients with primary open-angle glaucoma., In: Joint Editors-in-Chief: Stephen B. Kaye, Colin E. Willoughby, BMJ Open Ophthalmology. 2017.
Wong Y.H.I., Wong L.M.R., Gangwani R.A., Chan J.C.H., Kawasaki R. and Chong V., Macular Optical Coherence Tomography Improves Cost‑Effectiveness of Screening for Diabetic Macular Edema, Canadian Ophthalmological Society Annual Meeting 2018.
ZHU M., Lai J.S.M., Choy N.K.B., Shum J.W.H., Lo A.C.Y., Ng L.K.A., Chan J.C.H. and So K.F., Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health., In: Chief Editor: Einar Stefansson, Acta Ophthalmologica. 2018.


Researcher : Chan SKK

List of Research Outputs

Shih K.C., Yim S.M., Chan S.K.K. and Lai J.S.M., Management of Intraoperative Prolapse during Cataract Surgery, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.


Researcher : Chan TCY

List of Research Outputs

Chan T.C.Y., Wan K.H., Shih K.C. and Jhanji V., Advances in dry eye imaging: the present and beyond, British Journal of Ophthalmology. 2017, bjophthalmol-2017-310759.
Chow S.W.S., Chan T.C.Y., Wong Y.H.I., Fan C.Y., Lai J.S.M. and Ng L.K.A., Early epithelial complications of accelerated trans-epithelial corneal crosslinking in treatment of keratoconus: a case series, International Ophthalmology. 2017.
Chuang J., Shih K.C., Chan T.C.Y., Wan K.H., Jhanji V. and Tong L., Preoperative optimization of ocular surface disease before cataract surgery, Journal of Cataract and Refractive Surgery. Elsevier, 2018, 43 (11): 1596 - 1607.
Jacob S., Agarwal A., Ng L.K.A., Kwok P.S.K. and Chan T.C.Y., White Ring Sign and Sequential Segmental Terminal Lenticular Side Cut Dissection for Uneventful and Complete Lenticular Extraction in SMILE, Journal of Refractive Surgery. 2018, 34: 140-141.
Ng L.K.A., Cheng G.P.M., Woo C.P.V., Jhanji V. and Chan T.C.Y., Comparing a new hydroexpression technique with conventional forceps method for SMILE lenticule removal, British Journal of Ophthalmology. 2017, bjophthalmol-2017-310993.
Ng L.K.A., Kwok P.S.K. and Chan T.C.Y., Secondary Lenticule Remnant Removal After SMILE, Journal of Refractive Surgery. 2017, 33: 779-782.
Wei P., Wang Y., Chan T.C.Y., Ng L.K.A., Cheng G.P.M. and Jhanji V., Determining total corneal power after small-incision lenticule extraction in myopic eyes, Journal of Cataract & Refractive Surgery. 2017, 43: 1450-1457.


Researcher : Cheung JJC

Project Title:Dry Eyes and Thyroid Eye Disease
Investigator(s):Cheung JJC
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research for New Staff
Start Date:04/2017


Project Title:The Association of Research in Vision and Ophthalmology 2018 Annual Meeting; Phacoemulsification Cataract Surgery in Patients Receiving Novel Oral Anticoagulant
Investigator(s):Cheung JJC
Department:Ophthalmology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2018


Project Title:Medpor Orbital Implant for Evisceration, Enucleation and Orbital Reconstruction Surgery
Investigator(s):Cheung JJC, Tang RKT
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:06/2018


List of Research Outputs

Cheung J.J.C., Lower eyelid management in facial nerve palsy, Hong Kong Facial Nerve Palsy Symposium. 2017.
Cheung J.J.C., My most challenging case(s)in Oculoplastics, Asia Pacific Academy of Ophthalmology. 2018.
Cheung J.J.C., Liu S. and Li K.K.W., Phacoemulsification cataract surgery in patients receiving novel oral anticoagulant medications, International Ophthalmology. 2018.
Cheung J.J.C., Li K.K.W. and Liu S., Phacoemulsification cataract surgery in patients receiving novel oral anticoagulant medications, The Association of Research in Vision and Ophthalmology, 2018.
Cheung J.J.C., Li K.K.W. and Tang S.W.K., Retrospective review on the outcome and safety of transscleral diode laser cyclophotocoagulation in refractory glaucoma in Chinese patients, International Ophthalmology. 2017.
Cheung J.J.C. and Chong S.S.Y., Two cases of IgG4-related sclerosing disease presenting at the tarsal conjunctiva, Asia Pacific Academy of Ophthalmology, 2018.


Researcher : Cheung ND

List of Research Outputs

Chan Y.K., Csanner G., Shum H.C., Williams R.L., Cheung N.D. and Wong D.S.H., Towards Better Characterisation And Quantification Of Emulsification Of Silicone Oil In Vitro., Acta Ophthalmologica. 2017, 95: e385-e392.


Researcher : Chiu K

Project Title:Investigating the neuroprotective effects of trans-scleral electrical stimulation in a laser induced chronic rat ocular hypertension model
Investigator(s):Chiu K, Lai JSM, So KF
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016
Completion Date:12/2017


Project Title:Retinal microglia as a therapeutic target of the traditional Chinese medicine Lycium barbarum in Alzheimer’s disease-related vision loss
Investigator(s):Chiu K, Chang RCC, So KF
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2017


Project Title:Development of Wolfberry as Herbal Medicine to Modulate Systemic Inflammation and Neuroinflammation for Alzheimer's Disease
Investigator(s):Chiu K, Hu Y, Chang RCC, Mak HKF, So KF, Lai JSM, Chan HLH, Lam TC
Department:Ophthalmology
Source(s) of Funding:Midstream Research Programme for Universities (MRP)
Start Date:04/2018


Project Title:Development of Wolfberry as Herbal Medicine to Modulate Systemic Inflammation and Neuroinflammation for Alzheimer's Disease
Investigator(s):Chiu K, Hu Y, Chang RCC, Mak HKF, So KF, Lai JSM, Chan HLH, Lam TC
Department:Ophthalmology
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:04/2018


Project Title:Development of Wolfberry as Herbal Medicine to Modulate Systemic Inflammation and Neuroinflammation for Alzheimer's Disease
Investigator(s):Chiu K, Hu Y, Chang RCC, Mak HKF, So KF, Lai JSM, Chan HLH, Lam TC
Department:Ophthalmology
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:06/2018


List of Research Outputs

Manthey A.L., Chiu K. and So K.F., Effects of Lycium barbarum on the Visual System, In: Bai-Yun Zeng, Kaicun Zhao, International Review of Neurobiology: Neurobiology of Chinese Herbal Medicine, Volume 135 . Elservier, 2017, 135: 1-27.


Researcher : Chow SWS

List of Research Outputs

Chow S.W.S., Chan T.C.Y., Wong Y.H.I., Fan C.Y., Lai J.S.M. and Ng L.K.A., Early epithelial complications of accelerated trans-epithelial corneal crosslinking in treatment of keratoconus: a case series, International Ophthalmology. 2017.


Researcher : Choy BNK

Project Title:Randomized control trial on the effectiveness of collagen cross-linking on bullous keratopathy
Investigator(s):Choy NKB, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2015


Project Title:Randomized control trial on the effectiveness of collagen cross-linking on bullous keratopathy
Investigator(s):Choy NKB, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Dr. Timothy Kai-ching Liu Memorial Fund
Start Date:01/2016


Project Title:The neuro-protective effects of physical exercise on retinal ganglion cells in a rat model of acute intraocular pressure elevation
Investigator(s):Choy NKB, Lo ACY, So KF, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2016
Completion Date:06/2018


Project Title:Evaluation of the impact of a Patient Decision Aid (PDA) developed for Chinese primary open angle glaucoma patients
Investigator(s):Choy NKB, Lam WWT, Shum JWH
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2018


Project Title:13th European Glaucoma Society Congress; The association between Haemodialysis And Optic Neuropathy
Investigator(s):Choy NKB
Department:Ophthalmology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2018


Project Title:Use of Fibrin Glue for Pterygium Surgery
Investigator(s):Choy NKB, Lai JSM
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:06/2018


Project Title:Treatment of Ocular Surface Disease in Glaucoma Subjects with Topical cyclosporine Eye Drop
Investigator(s):Choy NKB
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:06/2018


List of Research Outputs



Researcher : Choy NKB

Project Title:Randomized control trial on the effectiveness of collagen cross-linking on bullous keratopathy
Investigator(s):Choy NKB, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2015


Project Title:Randomized control trial on the effectiveness of collagen cross-linking on bullous keratopathy
Investigator(s):Choy NKB, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Dr. Timothy Kai-ching Liu Memorial Fund
Start Date:01/2016


Project Title:The neuro-protective effects of physical exercise on retinal ganglion cells in a rat model of acute intraocular pressure elevation
Investigator(s):Choy NKB, Lo ACY, So KF, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2016
Completion Date:06/2018


Project Title:Evaluation of the impact of a Patient Decision Aid (PDA) developed for Chinese primary open angle glaucoma patients
Investigator(s):Choy NKB, Lam WWT, Shum JWH
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2018


Project Title:13th European Glaucoma Society Congress; The association between Haemodialysis And Optic Neuropathy
Investigator(s):Choy NKB
Department:Ophthalmology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2018


Project Title:Use of Fibrin Glue for Pterygium Surgery
Investigator(s):Choy NKB, Lai JSM
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:06/2018


Project Title:Treatment of Ocular Surface Disease in Glaucoma Subjects with Topical cyclosporine Eye Drop
Investigator(s):Choy NKB
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:06/2018


List of Research Outputs

Chan H.M.H., Choy N.K.B. and Lai J.S.M., Effects of Riboflavin and Ultraviolet Illumination on the Biomechanical Properties of Conjunctiva, Ophthalmic Research. 2017.
Chan J.C.W., Choy N.K.B., Chan O.C.C. and Li K.K.W., Early intraocular pressure change after peripheral iridotomy with ultralow fluence pattern scanning laser and Nd:YAG laser in primary angle-closure suspect: Kowloon East Pattern Scanning Laser Study Report No. 3, Graefe's Archive for Clinical and Experimental Ophthalmology. 2018, 256: 363-369.
Choy N.K.B., A patient decision aid for glaucoma management, Tianjin International Ophthalmology Forum 2018.
Choy N.K.B., Comparison of surgical outcome of trabeculectomy and phacotrabeculectomy in Chinese glaucoma patients, International Journal of Ophthalmology. 2017, 10: 1928-1930.
Choy N.K.B., Lid problems in Glaucoma patients, 19th China Mobile Eye Treatment Centres Annual Seminar. 2017.
Choy N.K.B., Non-penetrating deep sclerectomy using CO2 laser, 4th Asia Pacific Glaucoma Congress. 2018.
Choy N.K.B., Oculoplastic issues in Glaucoma patients, The Cross-Strait Four Regions Ophthalmologic Symposium. 2017.
Choy N.K.B., Randomized control trial on the effectiveness of collagen crosslinking on bullous keratopathy, The 9th Annual Congress on Controversies in Ophthalmology. 2018.
Choy N.K.B., The association between Hemodialysis And Optic Neuropathy, European Glaucoma Society Congress. 2018.
Shum J.W.H., Lam W.W.T., Choy N.K.B., Chan J.C.H., Ho W.L. and Lai J.S.M., Development and pilot-testing of patient decision aid for use among Chinese patients with primary open-angle glaucoma., In: Joint Editors-in-Chief: Stephen B. Kaye, Colin E. Willoughby, BMJ Open Ophthalmology. 2017.
Tong M.K., Fan C.Y., Choy N.K.B. and Li K.K.W., Topical Lidocaine Gel in Pan-retinal Photocoagulation by Pattern Scanning Laser (Kowloon East Pattern Scanning Laser Report No. 2), Ophthalmology Retina. 2018, 2: 379-380.
ZHU M., Lai J.S.M., Choy N.K.B., Shum J.W.H., Lo A.C.Y., Ng L.K.A., Chan J.C.H. and So K.F., Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health., In: Chief Editor: Einar Stefansson, Acta Ophthalmologica. 2018.


Researcher : FU L

List of Research Outputs

FU L., Fung K.C.F., Lo A.C.Y., Chan Y.K., So K.F., Wong Y.H.I., Shih K.C. and Lai J.S.M., Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury, Translational Vision Science and Technology. 2018, 7:3.


Researcher : Fan CY

List of Research Outputs

Chow S.W.S., Chan T.C.Y., Wong Y.H.I., Fan C.Y., Lai J.S.M. and Ng L.K.A., Early epithelial complications of accelerated trans-epithelial corneal crosslinking in treatment of keratoconus: a case series, International Ophthalmology. 2017.
Tong M.K., Fan C.Y., Choy N.K.B. and Li K.K.W., Topical Lidocaine Gel in Pan-retinal Photocoagulation by Pattern Scanning Laser (Kowloon East Pattern Scanning Laser Report No. 2), Ophthalmology Retina. 2018, 2: 379-380.


Researcher : Fung KCF

List of Research Outputs

FU L., Fung K.C.F., Lo A.C.Y., Chan Y.K., So K.F., Wong Y.H.I., Shih K.C. and Lai J.S.M., Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury, Translational Vision Science and Technology. 2018, 7:3.
Lo A.C.Y., Tang L.H.C., LAI K.W. and Fung K.C.F., Autophagy in diabetic retinal ischemia/reperfusion injury, Neuroscience 2017, The 47th Annual Meeting, Society for Neuroscience. 2017.
Tang L.H.C., Fung K.C.F. and Lo A.C.Y., Autophagy in Hypoxic R28 Retinal Precursor Cells, The 33rd Asia-Pacific Academy of Ophthalmology Congress 2018.


Researcher : Gangwani RA

List of Research Outputs

Jiao F., Wong C.K.H., Tang S.C.W., Fung S.C.C., Tan K.C.B., McGhee S., Gangwani R.A. and Lam C.L.K., Annual direct medical costs associated with diabetes-related complications in the event year and in subsequent years in Hong Kong., Diabet Med.. 2018, 34(9): 1276-1283.
Jiao F., Wong C.K.H., Gangwani R.A., Tan K.C.B., Tang S.C.W. and Lam C.L.K., Health-related quality of life and health preference of Chinese patients with diabetes mellitus managed in primary care and secondary care setting: decrements associated with individual complication and number of complications, Health and Quality of Life Outcomes. 2017, 15: 125.
Wong Y.H.I., Wong L.M.R., Gangwani R.A., Chan J.C.H., Kawasaki R. and Chong V., Macular Optical Coherence Tomography Improves Cost‑Effectiveness of Screening for Diabetic Macular Edema, Canadian Ophthalmological Society Annual Meeting 2018.


Researcher : Ho WL

List of Research Outputs

Shum J.W.H., Lam W.W.T., Choy N.K.B., Chan J.C.H., Ho W.L. and Lai J.S.M., Development and pilot-testing of patient decision aid for use among Chinese patients with primary open-angle glaucoma., In: Joint Editors-in-Chief: Stephen B. Kaye, Colin E. Willoughby, BMJ Open Ophthalmology. 2017.


Researcher : LAI KW

List of Research Outputs

Lo A.C.Y., Tang L.H.C., LAI K.W. and Fung K.C.F., Autophagy in diabetic retinal ischemia/reperfusion injury, Neuroscience 2017, The 47th Annual Meeting, Society for Neuroscience. 2017.


Researcher : Lai JSM

Project Title:To introduce Ologen implant in glaucoma filter surgery for the treatment of glaucoma at Queen Mary Hospital and United Christian Hospital
Investigator(s):Lai JSM, Chan JCH
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2010


Project Title:To introduce ExPRESS shunt in glaucoma filter surgery for the treatment of glaucoma at Queen Mary Hospital
Investigator(s):Lai JSM, Lee WYJ
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2012


Project Title:Randomized control trial on the neuroprotective effects of oral Wolfberry supplement in the treatment of normal tension glaucoma
Investigator(s):Lai JSM, So KF, Chang RCC, Lee WYJ, Chan JCH, Lo ACY
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:12/2014


Project Title:Biologic agents therapy in non-infectious uveitis
Investigator(s):Lai JSM
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2017


List of Research Outputs

Chan H.M.H., Choy N.K.B. and Lai J.S.M., Effects of Riboflavin and Ultraviolet Illumination on the Biomechanical Properties of Conjunctiva, Ophthalmic Research. 2017.
Chow S.W.S., Chan T.C.Y., Wong Y.H.I., Fan C.Y., Lai J.S.M. and Ng L.K.A., Early epithelial complications of accelerated trans-epithelial corneal crosslinking in treatment of keratoconus: a case series, International Ophthalmology. 2017.
FU L., Fung K.C.F., Lo A.C.Y., Chan Y.K., So K.F., Wong Y.H.I., Shih K.C. and Lai J.S.M., Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury, Translational Vision Science and Technology. 2018, 7:3.
Shih K.C., Chuang J., Lun C., Tong L. and Lai J.S.M., Intense pulsed light therapy significantly relieves dry eye symptoms and improves tear film metrics in meibomian gland dysfunction through modulation of meibum quality and expressibility., Investigative Ophthalmology & Visual Science. 2017, 58(8): 2237.
Shih K.C., Yim S.M., Chan S.K.K. and Lai J.S.M., Management of Intraoperative Prolapse during Cataract Surgery, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.
Shih K.C., Ng L.K.A., Lai J.S.M., Yeow S., Li V. and Lo J., Prevalence of Symptomatic Dry Eye Disease in an Urban Chinese Community: A Cross-sectional Population-based Study, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.
Shum J.W.H., Lam W.W.T., Choy N.K.B., Chan J.C.H., Ho W.L. and Lai J.S.M., Development and pilot-testing of patient decision aid for use among Chinese patients with primary open-angle glaucoma., In: Joint Editors-in-Chief: Stephen B. Kaye, Colin E. Willoughby, BMJ Open Ophthalmology. 2017.
ZHU M., Lai J.S.M., Choy N.K.B., Shum J.W.H., Lo A.C.Y., Ng L.K.A., Chan J.C.H. and So K.F., Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health., In: Chief Editor: Einar Stefansson, Acta Ophthalmologica. 2018.


Researcher : Lai WKW

Project Title:Open label, prospective, double arm, randomized, pilot study to evaluate the safety and efficacy of the same day administration of PDT with verteporfin and an intravitreal injection of ranibizumab vs. ranibizumab monotherapy for the treatment of subfoveal CNV secondary to neovascular age related macular degeneration in the Asian population
Investigator(s):Lai WKW, Li KKW, Wong DSH, McGhee S, Lam CLK, Chan WSC
Department:LKS Medical Faculty
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:07/2008


Project Title:Production of Iris Pigment Epithelial Cells for transplantation to treat Age-Related Macular Degeneration
Investigator(s):Lai WKW, Lo ACY, Fletcher C, Wong DSH
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2009




Researcher : Lai WWK

Project Title:Open label, prospective, double arm, randomized, pilot study to evaluate the safety and efficacy of the same day administration of PDT with verteporfin and an intravitreal injection of ranibizumab vs. ranibizumab monotherapy for the treatment of subfoveal CNV secondary to neovascular age related macular degeneration in the Asian population
Investigator(s):Lai WKW, Li KKW, Wong DSH, McGhee S, Lam CLK, Chan WSC
Department:LKS Medical Faculty
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:07/2008


Project Title:Production of Iris Pigment Epithelial Cells for transplantation to treat Age-Related Macular Degeneration
Investigator(s):Lai WKW, Lo ACY, Fletcher C, Wong DSH
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2009




Researcher : Lam WC

List of Research Outputs

Gan N., Zimmer C. and Lam W.C., Multi-Spectral Imaging of Circumscribed Choroidal Hemangioma Introduction, Ophthalmic Surgery, Lasers and Imaging Retina. 2017, 48: 572-575.


Researcher : Lee JWY

Project Title:The use of shunts in the treatment of uveitic glaucoma
Investigator(s):Lee WYJ, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2012




Researcher : Lee WYJ

Project Title:The use of shunts in the treatment of uveitic glaucoma
Investigator(s):Lee WYJ, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2012




Researcher : Li KKW

Project Title:Diabetic retinopathy screening for specialist care
Investigator(s):Li KKW, McGhee S, Gangwani RA, Lian J
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2014


List of Research Outputs

Tong M.K., Fan C.Y., Choy N.K.B. and Li K.K.W., Topical Lidocaine Gel in Pan-retinal Photocoagulation by Pattern Scanning Laser (Kowloon East Pattern Scanning Laser Report No. 2), Ophthalmology Retina. 2018, 2: 379-380.


Researcher : Lian Q

Project Title:The Roles and Mechanisms of human mesenchymal stem cell-mediated cardial protection against anthracycline-induced cardiomyopathy
Investigator(s):Lian Q
Department:Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2012


Project Title:The Roles and Mechanisms of RAP1/NFkb signaling pathway in MSC-induced immunomodulation for organ transplantation
Investigator(s):Lian Q, Poon MW, He J
Department:Medicine
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2013


Project Title:Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application
Investigator(s):Lian Q, Tse HF, Poon MW
Department:Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:01/2013


Project Title:Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application
Investigator(s):Lian Q, Tse HF, Poon MW
Department:Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:04/2013


Project Title:Generation, Purification and Transplantation of human Pluripotent Stem Cell -derived Cone and Rod Photoreceptor Cells for Retinal Degenerative Disease
Investigator(s):Lian Q, Wong DSH
Department:Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2013


Project Title:International Society for Stem Cell Research 11th Annual Meeting; ACTIVATION OF NRG1/ERBB4 SIGNALING PATHYWAY IN MESENCHYMAL STEM CELLS ENHANCES CELL SURVIAL AND PARACRINE POTENTIALS AGAINST MYOCARDIAL INFARCTION
Investigator(s):Lian Q
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2013


Project Title:Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application
Investigator(s):Lian Q, Tse HF, Poon MW
Department:Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2013


Project Title:Functional roles of human ESC/iPSC-derived mesenchymal stem cell-deposited matrixes for improving survive and functions of retinal pigment epithelial cell (RPE)
Investigator(s):Lian Q
Department:Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2014


Project Title:Functional Roles of Procollagen 2a1 in the Regulation of Nkx2.5+Cardiac Progenitor Cells for Myocardial Regeneration
Investigator(s):Lian Q, Zhang Y
Department:Ophthalmology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2016


Project Title:Human induced pluripotent stem cells derived-nucleus pulposus cells for intervertebral disc degeneration in rats
Investigator(s):Lian Q, Zhang Y, Cheah KSE
Department:Ophthalmology
Source(s) of Funding:AO Spine Asia Pacific
Start Date:06/2016


Project Title:Regulation of mitochondrial transfer potency by Kif5b in mesenchymal stem cells to rescue mitochondrial dysfunction-provoked ganglion cell degeneration
Investigator(s):Lian Q, Huang J, Chiu K
Department:Ophthalmology
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2016


Project Title:Klf4 interacts with PCG-1/ERR to regulate mitochondrial biogenesis and dynamics in rescuing complex I dysfunction-provoked mesenchymal stem cell ageing
Investigator(s):Lian Q, Tse HF, Yan B
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2017


Project Title:International Society of Stem Cell Research (ISSCR) 2018 annunal Meeting ; HUMAN ISOGENIC AND PATIENT’S PLURIPOTENT STEM CELLS TO MODEL BIETTI’S CRYSTALLINE RETINAL DYSTROPHY
Investigator(s):Lian Q
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2018




Researcher : Lo ACY

Project Title:Characterization and isolation of active autophagy components from Radix Polygalae (Yuan Zhi) for the modulation of age-related neurodegenerative diseases
Investigator(s):Lo ACY
Department:Ophthalmology
Source(s) of Funding:Macau Science and Technology Development Fund
Start Date:07/2014


Project Title:Alleviation of early high mortality and aggravated brain pathology by lutein in a genetic type I diabetic mouse model after experimental stroke
Investigator(s):Lo ACY
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2016


Project Title:Studies on the influence of maternal diabetes in retinopathy of prematurity using the diabetic Ins2Akita mouse model
Investigator(s):Lo ACY
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


Project Title:Lutein and candesartan co-treatment delays the progression of non-proliferative diabetic retinopathy in the diabetic Ins2Akita mouse model
Investigator(s):Lo ACY, Wong YHI
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2017


Project Title:Neuroscience 2017; Autophagy in diabetic retinal ischemia/reperfusion injury
Investigator(s):Lo ACY
Department:Ophthalmology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2017
Completion Date:11/2017


Project Title:Vascular pathophysiology and neuronal dysfunction in gestational diabetes-associated retinopathy of prematurity
Investigator(s):Lo ACY, Lam WC
Department:Ophthalmology
Source(s) of Funding:Germany/Hong Kong Joint Research Scheme
Start Date:01/2018


Project Title:Light-inducible intraocular cell-based drug delivery platform
Investigator(s):Lo ACY
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2018


Project Title:Beneficial effects of lutein in maternal diabetes-related retinopathy of prematurity using the diabetic Ins2Akita mouse model
Investigator(s):Lo ACY, Lam WC
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2018


List of Research Outputs

FU L., Fung K.C.F., Lo A.C.Y., Chan Y.K., So K.F., Wong Y.H.I., Shih K.C. and Lai J.S.M., Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury, Translational Vision Science and Technology. 2018, 7:3.
Fu Z., Meng S.S., Burnim S.B., Smith L.E. and Lo A.C.Y., Lutein facilitates physiological revascularization in a mouse model of retinopathy of prematurity, Clin Exp Ophthalmol. 2017, 45(5): 529-538.
Lo A.C.Y., Tang L.H.C., LAI K.W. and Fung K.C.F., Autophagy in diabetic retinal ischemia/reperfusion injury, Neuroscience 2017, The 47th Annual Meeting, Society for Neuroscience. 2017.
Lo A.C.Y., Gel-based drug delivery system, “The current state of posterior drug delivery system: What is on the horizon?” 2018 World Ophthalmology Congress. 2018.
TSANG K.W. and Lo A.C.Y., Abnormal retinal function and vasculature in mouse neonates with hyperglycemic mother after oxygen-induced retinopathy, ARVO 2018 Annual Meeting. 2018.
TSANG K.W. and Lo A.C.Y., Maternal diabetes did not affect retinal vascular development under normal condition, The 22nd Research Postgraduate Symposium, LKS Faculty of Medicine. 2017.
TSANG K.W. and Lo A.C.Y., Neonates from Diabetic Mouse Mothers Displayed a Normal Retinal Development, 13th International Symposium on Healthy Aging: “Aging Health Happiness”. 2018.
Tang L.H.C., Wong Y.H.I. and Lo A.C.Y., Animal Models of Diabetic Retinopathy Part 1 and Part 2, In: Ibeh Bartholomew, Experimetnal Animal Models of Human Diseases – An Effective Therapeutic Strategy. IntechOpen, 2018, 13-39, 41-68.
Tang L.H.C., Fung K.C.F. and Lo A.C.Y., Autophagy in Hypoxic R28 Retinal Precursor Cells, The 33rd Asia-Pacific Academy of Ophthalmology Congress 2018.
Tsang K.K., Wong S.Y., Yao K.M., Chan B.P. and Lo A.C.Y., Doxycycline-terminable intraocular drug delivery cell-encapsulating device, The 33rd Asia-Pacific Academy of Ophthalmology Congress 2018.
WANG W. and Lo A.C.Y., Diabetic Retinopathy: Pathophysiology and Treatments, Int J Mol Sci. 2018.
WANG W. and Lo A.C.Y., Studies on early treatment for diabetic retinopathy using the ins2akita mice, 13th International Symposium on Healthy Aging: “Aging Health Happiness”. 2018.
WANG W. and Lo A.C.Y., Study on the effect of lutein in an experimental model of diabetic retinopathy using the Ins2Akita mice, ARVO 2018 Annual Meeting. 2018.
YANG D., So K.F. and Lo A.C.Y., Lycium barbarum polysaccharides extracts preserve retinal function and attenuate inner retinal neuronal damage in a mouse model of transient retinal ischemia, Clin Exp Ophthalmol. 2017, 45(7): 717-729.
ZHU M., Lai J.S.M., Choy N.K.B., Shum J.W.H., Lo A.C.Y., Ng L.K.A., Chan J.C.H. and So K.F., Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health., In: Chief Editor: Einar Stefansson, Acta Ophthalmologica. 2018.


Researcher : Manthey AL

List of Research Outputs

Manthey A.L., Chiu K. and So K.F., Effects of Lycium barbarum on the Visual System, In: Bai-Yun Zeng, Kaicun Zhao, International Review of Neurobiology: Neurobiology of Chinese Herbal Medicine, Volume 135 . Elservier, 2017, 135: 1-27.


Researcher : Marcet MM

Project Title:Eyelid malposition after cataract and refractive surgery: an anatomic model
Investigator(s):Marcet MM, So KF
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2011


Project Title:Pretarsal versus preseptal botulinum toxin for patients with eyelid spasm: a randomized, double-masked placebo controlled trial
Investigator(s):Marcet MM, Ho SL, Cowling BJ
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2015




Researcher : Ng LK

Project Title:To Introduce Boston Keratoprosthesis for the Treatment of Corneal Blindness in Queen Mary Hospital
Investigator(s):Ng LKA, Chan SKK, Yim SM, Shih KC
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2016


Project Title:Relationship among dietary habits, omega-3 fatty acids levels and age-related macular degeneration in the Hong Kong Chinese
Investigator(s):Ng LKA, Wong YHI, Lee CYJ, Ho WL
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2016
Completion Date:03/2019


List of Research Outputs



Researcher : Ng LKA

Project Title:To Introduce Boston Keratoprosthesis for the Treatment of Corneal Blindness in Queen Mary Hospital
Investigator(s):Ng LKA, Chan SKK, Yim SM, Shih KC
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2016


Project Title:Relationship among dietary habits, omega-3 fatty acids levels and age-related macular degeneration in the Hong Kong Chinese
Investigator(s):Ng LKA, Wong YHI, Lee CYJ, Ho WL
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2016
Completion Date:03/2019


List of Research Outputs

Chow S.W.S., Chan T.C.Y., Wong Y.H.I., Fan C.Y., Lai J.S.M. and Ng L.K.A., Early epithelial complications of accelerated trans-epithelial corneal crosslinking in treatment of keratoconus: a case series, International Ophthalmology. 2017.
Jacob S., Agarwal A., Ng L.K.A., Kwok P.S.K. and Chan T.C.Y., White Ring Sign and Sequential Segmental Terminal Lenticular Side Cut Dissection for Uneventful and Complete Lenticular Extraction in SMILE, Journal of Refractive Surgery. 2018, 34: 140-141.
Ma A., Mak M.S., Shih K.C., Tsui C.K., Cheung R.K., Lee S.H., Leung H., Leung J.N., Leung J.T., Van-Boswell M.Z., Wong M.T., Ng L.K.A., Lee C.H.P., Jhanji V. and Tong L., Association of long-term glycaemic control on tear break up times and dry eye symptoms in Chinese patients with type 2 diabetes, Clinical & Experimental Ophthalmology. 2018.
Ma A., Mak M., Ng L.K.A. and Shih K.C., Prevalence and Risk Factors for Dry Eye Disease in Chinese Type II Diabetics, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.
Ng L.K.A., Cheng G.P.M., Woo C.P.V., Jhanji V. and Chan T.C.Y., Comparing a new hydroexpression technique with conventional forceps method for SMILE lenticule removal, British Journal of Ophthalmology. 2017, bjophthalmol-2017-310993.
Ng L.K.A., Kwok P.S.K. and Chan T.C.Y., Secondary Lenticule Remnant Removal After SMILE, Journal of Refractive Surgery. 2017, 33: 779-782.
Shih K.C., Ng L.K.A., Lai J.S.M., Yeow S., Li V. and Lo J., Prevalence of Symptomatic Dry Eye Disease in an Urban Chinese Community: A Cross-sectional Population-based Study, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.
Wei P., Wang Y., Chan T.C.Y., Ng L.K.A., Cheng G.P.M. and Jhanji V., Determining total corneal power after small-incision lenticule extraction in myopic eyes, Journal of Cataract & Refractive Surgery. 2017, 43: 1450-1457.
ZHU M., Lai J.S.M., Choy N.K.B., Shum J.W.H., Lo A.C.Y., Ng L.K.A., Chan J.C.H. and So K.F., Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health., In: Chief Editor: Einar Stefansson, Acta Ophthalmologica. 2018.


Researcher : Shih KC

Project Title:Understanding the effect of intense pulsed light therapy on meibomian gland dysfunction-related dry eye disease: A randomized sham-controlled clinical trial
Investigator(s):Shih KC
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:07/2017
Completion Date:11/2017


Project Title:2018 Biennial Scientific Meeting of the Asia Cornea Society; Prevalence and severity of smartphone addiction and dry eye disease in university students
Investigator(s):Shih KC
Department:Ophthalmology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2018
Completion Date:05/2018


List of Research Outputs

Chan T.C.Y., Wan K.H., Shih K.C. and Jhanji V., Advances in dry eye imaging: the present and beyond, British Journal of Ophthalmology. 2017, bjophthalmol-2017-310759.
Chuang J., Shih K.C., Chan T.C.Y., Wan K.H., Jhanji V. and Tong L., Preoperative optimization of ocular surface disease before cataract surgery, Journal of Cataract and Refractive Surgery. Elsevier, 2018, 43 (11): 1596 - 1607.
FU L., Fung K.C.F., Lo A.C.Y., Chan Y.K., So K.F., Wong Y.H.I., Shih K.C. and Lai J.S.M., Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury, Translational Vision Science and Technology. 2018, 7:3.
Ho Y.T. and Shih K.C., Research Internship Scheme 2017-2018, Li Ka Shing Faculty of Medicine, University of Hong Kong. 2017.
Ma A., Mak M.S., Shih K.C., Tsui C.K., Cheung R.K., Lee S.H., Leung H., Leung J.N., Leung J.T., Van-Boswell M.Z., Wong M.T., Ng L.K.A., Lee C.H.P., Jhanji V. and Tong L., Association of long-term glycaemic control on tear break up times and dry eye symptoms in Chinese patients with type 2 diabetes, Clinical & Experimental Ophthalmology. 2018.
Ma A., Mak M., Ng L.K.A. and Shih K.C., Prevalence and Risk Factors for Dry Eye Disease in Chinese Type II Diabetics, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.
Shih K.C., Asia Cornea Society - Santen Asia Educational Observership Grant 2017, Asia Cornea Society. 2017.
Shih K.C., Asia Pacific Academy of Ophthalmology Achievement Award 2018, Asia Pacific Academy of Ophthalmology. 2018.
Shih K.C., Kua W.N., Chan C., Wong Y.H.I. and Yiu K.H., Diabetic Retinopathy Status as a Marker for More Severe Reduction in Circulating Endothelial Progenitor Cells and Systemic Atherosclerosis in Diabetics, Annual Scientific Meeting of the Japanese Ophthalmological Society 2018.
Shih K.C., Distinguished Young Fellow 2017, Hong Kong Academy of Medicine. 2017.
Shih K.C., Global Ambassador (Hong Kong), Tear Film and Ocular Surface Society. 2017.
Shih K.C., Chuang J., Lun C., Tong L. and Lai J.S.M., Intense pulsed light therapy significantly relieves dry eye symptoms and improves tear film metrics in meibomian gland dysfunction through modulation of meibum quality and expressibility., Investigative Ophthalmology & Visual Science. 2017, 58(8): 2237.
Shih K.C., Yim S.M., Chan S.K.K. and Lai J.S.M., Management of Intraoperative Prolapse during Cataract Surgery, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.
Shih K.C., Wai H.Y., Jhanji V. and Tong L., Prevalence and severity of smartphone addiction and dry eye disease in university students, International Ocular Surface Society Annual Meeting 2018.
Shih K.C., Ng L.K.A., Lai J.S.M., Yeow S., Li V. and Lo J., Prevalence of Symptomatic Dry Eye Disease in an Urban Chinese Community: A Cross-sectional Population-based Study, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.
Shih K.C., Lun C.N., Tong L. and Jhanji V., Systematic Review of Randomized controlled trials in the Treatment of Dry Eye Disease in Sjogren Syndrome, Annual Meeting of the Asia Pacific Academy of Ophthalmology 2018.
Shih K.C., Lun C.N., Jhanji V., Thong B.Y. and Tong L., Systematic review of randomized controlled trials in the treatment of dry eye disease in Sjogren syndrome, Journal of Inflammation. United Kingdom, 2017, 14: 26.
Shih K.C., Travel Grant for the 122nd Annual Meeting of the Japanese Ophthalmological Society, Japanese Ophthalmological Society. 2018.


Researcher : Shum JWH

Project Title:Comparison and correlation of the Hong Kong University of Science and Technology (HKUST) contact lens tonometer with Sensimed Triggerfish contact lens
Investigator(s):Shum JWH, Lai JSM
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research for New Staff
Start Date:07/2014


Project Title:World Glaucoma Congress 2017; Visual Field Compromised In Patients Suffering From Severe Menorrhagia
Investigator(s):Shum JWH
Department:Ophthalmology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2017
Completion Date:07/2017


List of Research Outputs

Shum J.W.H., Lam W.W.T., Choy N.K.B., Chan J.C.H., Ho W.L. and Lai J.S.M., Development and pilot-testing of patient decision aid for use among Chinese patients with primary open-angle glaucoma., In: Joint Editors-in-Chief: Stephen B. Kaye, Colin E. Willoughby, BMJ Open Ophthalmology. 2017.
ZHU M., Lai J.S.M., Choy N.K.B., Shum J.W.H., Lo A.C.Y., Ng L.K.A., Chan J.C.H. and So K.F., Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health., In: Chief Editor: Einar Stefansson, Acta Ophthalmologica. 2018.


Researcher : So KF

Project Title:Potential Role of Adiponectin Signaling in Mediating Physical Exercise-Elicited Hippocampal Neurogenesis and Antidepressive Effects in Stressed Mice
Investigator(s):So KF, Xu A
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


Project Title:Study of gliogenesis and neurochemistry underlying psychomotor retardation induced by chronic stress and the therapeutic approach for motor training in reversing the adverse effects
Investigator(s):So KF, Wu W, Lee TMC
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


List of Research Outputs

Chau K.H.B., Keuper K.E., LO M., So K.F., Chan C.C.H. and Lee T.M.C., Meditation-induced neuroplastic changes of the prefrontal network are associated with reduced valence perception in older people, Brain and Neuroscience Advances. 2018, 2: 239821281877182.
FU L., Fung K.C.F., Lo A.C.Y., Chan Y.K., So K.F., Wong Y.H.I., Shih K.C. and Lai J.S.M., Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury, Translational Vision Science and Technology. 2018, 7:3.
Hu Y., Chen Z., Huang L., Xi Y., Li B., Wang H., Yan J., Lee T.M.C., Tao Q., So K.F. and Ren C., A translational study on looming-evoked defensive response and the underlying subcortical pathway in autism, Scientific Reports. 2017, 7: 14755.
Lin K., Xu G., Shi L., Lu W., Guan L., Ouyang H., Chen K., Dang Y., Zhou L. and So K.F., CACNA1C polymorphisms Impact Cognitive Recovery in Patients with Bipolar Disorder in a Six-week Open-label Trial, Scientific Reports. 2017, 7.
Lin K., Shao Z., Geng X., Chen K., Lu R., Gao Y., Bi Y., Lu W., Guan L., Kong J., Xu G. and So K.F., Illness, at-risk and resilience neural markers of bipolar disorder: a new clinical staging framework, Journal of Affective Disorders. 2018, 238: 16-23.
Manthey A.L., Chiu K. and So K.F., Effects of Lycium barbarum on the Visual System, In: Bai-Yun Zeng, Kaicun Zhao, International Review of Neurobiology: Neurobiology of Chinese Herbal Medicine, Volume 135 . Elservier, 2017, 135: 1-27.
Po K.T.K., Leung W.H.J., Chan N.M.J., Fung K.H.T., Sánchez-Vidaña D.I., Sin L.L.E., So K.F., Lau W.M.B. and Siu M.H.A., Protective effect of Lycium Barbarum polysaccharides on dextromethorphan-induced mood impairment and neurogenesis suppression, Brain Research Bulletin. 2017, 134: 10-17.
Shi Z., Zhu L., Li T., Tang X., Xiang Y., Han X., Xia L., Zeng L., Nie J., Huang Y., Tsang C.K., Wang Y., Lei Z., Xu Z., So K.F. and Ruan Y., Neuroprotective Mechanisms of Lycium barbarum Polysaccharides Against Ischemic Insults by Regulating NR2B and NR2A Containing NMDA Receptor Signaling Pathways, Frontiers in Cellular Neuroscience. 2017, 11.
Wang F., Tipoe G.L., Yang C., Nanji A.A., Hao X., So K.F. and Xiao J., Lycium barbarum Polysaccharide Supplementation Improves Alcoholic Liver Injury in Female Mice by Inhibiting Stearoyl-CoA Desaturase 1 , Molecular Nutrition & Food Research. 2018, 1800144.
Xiao J., Xing F., Liu Y., Lv Y., Wang X., Ling M.T., Gao H., Ouyang S., Yang M.I.N., Zhu J., Xia Y., So K.F. and Tipoe G.L., Garlic-derived compound S -allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway, Acta Pharmaceutica Sinica B. 2017.
YANG D., So K.F. and Lo A.C.Y., Lycium barbarum polysaccharides extracts preserve retinal function and attenuate inner retinal neuronal damage in a mouse model of transient retinal ischemia, Clin Exp Ophthalmol. 2017, 45(7): 717-729.
ZHU M., Lai J.S.M., Choy N.K.B., Shum J.W.H., Lo A.C.Y., Ng L.K.A., Chan J.C.H. and So K.F., Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health., In: Chief Editor: Einar Stefansson, Acta Ophthalmologica. 2018.


Researcher : TSANG KW

List of Research Outputs

TSANG K.W. and Lo A.C.Y., Abnormal retinal function and vasculature in mouse neonates with hyperglycemic mother after oxygen-induced retinopathy, ARVO 2018 Annual Meeting. 2018.
TSANG K.W. and Lo A.C.Y., Maternal diabetes did not affect retinal vascular development under normal condition, The 22nd Research Postgraduate Symposium, LKS Faculty of Medicine. 2017.
TSANG K.W. and Lo A.C.Y., Neonates from Diabetic Mouse Mothers Displayed a Normal Retinal Development, 13th International Symposium on Healthy Aging: “Aging Health Happiness”. 2018.


Researcher : Tong MK

List of Research Outputs

Tong M.K., Fan C.Y., Choy N.K.B. and Li K.K.W., Topical Lidocaine Gel in Pan-retinal Photocoagulation by Pattern Scanning Laser (Kowloon East Pattern Scanning Laser Report No. 2), Ophthalmology Retina. 2018, 2: 379-380.


Researcher : WANG W

List of Research Outputs

WANG W. and Lo A.C.Y., Diabetic Retinopathy: Pathophysiology and Treatments, Int J Mol Sci. 2018.
WANG W. and Lo A.C.Y., Studies on early treatment for diabetic retinopathy using the ins2akita mice, 13th International Symposium on Healthy Aging: “Aging Health Happiness”. 2018.
WANG W. and Lo A.C.Y., Study on the effect of lutein in an experimental model of diabetic retinopathy using the Ins2Akita mice, ARVO 2018 Annual Meeting. 2018.


Researcher : Wong DSH

Project Title:The Royal College of Ophthalmologists Annual Congress 2009 Can Lutein Protect the Outer Retina?
Investigator(s):Wong DSH
Department:LKS Medical Faculty
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2009


List of Research Outputs

Chan Y.K., Csanner G., Shum H.C., Williams R.L., Cheung N.D. and Wong D.S.H., Towards Better Characterisation And Quantification Of Emulsification Of Silicone Oil In Vitro., Acta Ophthalmologica. 2017, 95: e385-e392.


Researcher : Wong KWJ

List of Research Outputs

Chan J.C.H. and Wong K.W.J., Minimally Invasive Glaucoma Surgery, In: MOK Chun-on, CHAN Chi-fung Godfrey, CHAN Chi-kuen KING Wing-Keung Walter, LO See-kit Raymond, The Hong Kong Medical Diary. 香港醫訊, 2018.
Wong K.W.J., Conducting Research In Hong Kong: From Young Fellows Perspectives, 4th Medical Education Conference - Hong Kong Academy Of Medicine. 2018.
Wong K.W.J., Glaucoma And Biomechanical Properties Of Peripapillary Sclera, Ocular Biomechanics Workgroup Seminar 2018. 2018.
Wong K.W.J., Minimally Invasive Glaucoma Surgeries (MIGS) - An Overview, Hong Kong Glaucoma Interested Group Meeting. 2018.
Wong K.W.J., Minimally Invasive Glaucoma Surgery - An Overview, Tianjin International Ophthalmology and Optometry Forum 2018. 2018天津眼科及眼視光國 際論壇, 2018.


Researcher : Wong LMR

List of Research Outputs

Wong Y.H.I., Wong L.M.R., Gangwani R.A., Chan J.C.H., Kawasaki R. and Chong V., Macular Optical Coherence Tomography Improves Cost‑Effectiveness of Screening for Diabetic Macular Edema, Canadian Ophthalmological Society Annual Meeting 2018.


Researcher : Wong SY

List of Research Outputs

Tsang K.K., Wong S.Y., Yao K.M., Chan B.P. and Lo A.C.Y., Doxycycline-terminable intraocular drug delivery cell-encapsulating device, The 33rd Asia-Pacific Academy of Ophthalmology Congress 2018.


Researcher : Wong YHI

Project Title:To introduce ranibizumab (Licentis) for the treatment of diabetic macular edema to Queen Mary Hospital and to access the quality of life and utility values before and after the treatment
Investigator(s):Wong YHI, Wong DSH, Li KKW
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/2010


Project Title:To Introduce Ranibizumab (Lucentis) for the treatment of Retinal Vein Occlusion to Queen Mary Hospital
Investigator(s):Wong YHI, Wong DSH
Department:Ophthalmology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2014


Project Title:To investigate the risk profile for progression in patients with subclinical diabetic macular edema
Investigator(s):Wong YHI, Fong DYT
Department:Ophthalmology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2015


Project Title:A Retrospective Review of the Real Life Situation Regarding the Use of Anti-VEGF Agent in the Hospital Authority
Investigator(s):Wong YHI
Department:Ophthalmology
Source(s) of Funding:Bayer HealthCare Limited
Start Date:01/2017


Project Title:Chorioretinal changes when varying the dosage and fluence setting of verteporfin photodynamic therapy in an animal model
Investigator(s):Wong YHI, Lo ACY
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


List of Research Outputs

Chow S.W.S., Chan T.C.Y., Wong Y.H.I., Fan C.Y., Lai J.S.M. and Ng L.K.A., Early epithelial complications of accelerated trans-epithelial corneal crosslinking in treatment of keratoconus: a case series, International Ophthalmology. 2017.
FU L., Fung K.C.F., Lo A.C.Y., Chan Y.K., So K.F., Wong Y.H.I., Shih K.C. and Lai J.S.M., Transcorneal Electrical Stimulation Inhibits Retinal Microglial Activation and Enhances Retinal Ganglion Cell Survival After Acute Ocular Hypertensive Injury, Translational Vision Science and Technology. 2018, 7:3.
Lang H.H.B., Woo Y.C., Wong Y.H.I. and Chiu W.H.K., Single-session high-intensity focused ultrasound treatment for persistent or relapsed Graves Disease: preliminary exerpeince in a prospective study, Radiology. 2017, Epub ahead of print.
Shih K.C., Kua W.N., Chan C., Wong Y.H.I. and Yiu K.H., Diabetic Retinopathy Status as a Marker for More Severe Reduction in Circulating Endothelial Progenitor Cells and Systemic Atherosclerosis in Diabetics, Annual Scientific Meeting of the Japanese Ophthalmological Society 2018.
Tang L.H.C., Wong Y.H.I. and Lo A.C.Y., Animal Models of Diabetic Retinopathy Part 1 and Part 2, In: Ibeh Bartholomew, Experimetnal Animal Models of Human Diseases – An Effective Therapeutic Strategy. IntechOpen, 2018, 13-39, 41-68.
Wong Y.H.I., Wong L.M.R., Gangwani R.A., Chan J.C.H., Kawasaki R. and Chong V., Macular Optical Coherence Tomography Improves Cost‑Effectiveness of Screening for Diabetic Macular Edema, Canadian Ophthalmological Society Annual Meeting 2018.


Researcher : Woo CPV

List of Research Outputs

Ng L.K.A., Cheng G.P.M., Woo C.P.V., Jhanji V. and Chan T.C.Y., Comparing a new hydroexpression technique with conventional forceps method for SMILE lenticule removal, British Journal of Ophthalmology. 2017, bjophthalmol-2017-310993.


Researcher : YANG D

List of Research Outputs

YANG D., So K.F. and Lo A.C.Y., Lycium barbarum polysaccharides extracts preserve retinal function and attenuate inner retinal neuronal damage in a mouse model of transient retinal ischemia, Clin Exp Ophthalmol. 2017, 45(7): 717-729.


Researcher : Yim SM

List of Research Outputs

Shih K.C., Yim S.M., Chan S.K.K. and Lai J.S.M., Management of Intraoperative Prolapse during Cataract Surgery, European Society of Cataract and Refractive Surgeons Annual Meeting 2017.


Researcher : Yu CS

Project Title:Fat tissue engineering for facial recontouring
Investigator(s):Yu CS, Wong DSH, Lo ACY, Chan BP
Department:Ophthalmology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:09/2009




Researcher : ZHU M

List of Research Outputs

ZHU M., Lai J.S.M., Choy N.K.B., Shum J.W.H., Lo A.C.Y., Ng L.K.A., Chan J.C.H. and So K.F., Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health., In: Chief Editor: Einar Stefansson, Acta Ophthalmologica. 2018.


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