DEPT OF PHYSIOLOGY



Researcher : Ao Q

List of Research Outputs

Ao Q., Fung C.K., Tsui Y.P., Chan Y.S. and Shum D.K.Y., Chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells enhance regeneration of transected sciatic nerves of adult rats, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 69. 2009.
Fung C.K., Ao Q., Tsui Y.P., Shum D.K.Y. and Chan Y.S., Derivation of Schwann cells from mammalian skin and bone marrow for use in axonal regeneration, Soc. Neurosci. Abst. (USA), 327.13/C22. 2008.
Fung C.K., Ao Q., Tsui Y.P., Shum D.K.Y. and Chan Y.S., In vitro generation of Schwann cells from mammalian skin for bridging injured nerves, Proc. 6th Asian Biophysics Association Symposium. 2009, 161-162.
Tsui Y.P., Shea G.K.H., Ao Q., Chan Y.S. and Shum D.K.Y., Schwann cells derived from bone marrow stromal cells – in vitro study with dorsal root ganglia and in vivo study with peripheral nerve conduits. Neuroscience Research (Suppl 1): S, [31st Annual Meeting of Japan Neuroscience Society Tokyo. July 9-11, 2008 . 2008.


Researcher : Chan WH

List of Research Outputs

Chan W.H., Ho Y.S., Chung S.K. and Chung S.S.M., Synergistic effect of osmotic and oxidative stress in slow-developing cataract formation, Experimental Eye Research. 2008, 87: 454-461.


Researcher : Chan YS

List of Research Outputs

Ao Q., Fung C.K., Tsui Y.P., Chan Y.S. and Shum D.K.Y., Chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells enhance regeneration of transected sciatic nerves of adult rats, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 69. 2009.
Cham W.C., Ma C.W., Zhang Y., Xie H., Yung W.H., Chan Y.S. and Shum D.K.Y., Heparanase modulates synaptic plasticity at the hippocampus, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 77. 2009.
Cham W.C., Ma C.W., Zhang Y., Chan Y.S. and Shum D.K.Y., Role of heparanase in synaptic plasticity at the hippocampus and the vestibular nucleus, Proc. 6th Asian Biophysics Association Symposium. 2009, 167-168.
Chan Y.S., ‘When’ and ‘where’: Development of spatial perception, Proc. 6th Asian Biophysics Association Symposium, pp. 9-10. 2009.
Chan Y.S., BrainNavigator. 2008.
Chan Y.S., BrainNavigator. 2008.
Chan Y.S., Lai C.H., Lai S.K., Ma C.W. and Ng K.P., Developmental refinement of central vestibular pathway towards spatial recognition. , Acta Physiologica Sinica, 60 Suppl: 12. [Beijing Joint Conference of Physiological Sciences 2008. Beijing. Oct. 19-22, 2008] . 2008.
Chan Y.S., First Medallion of the Australian Neuroscience Society, 2008.
Chan Y.S., Innovation in the teaching of neuroscience in the medical curriculum. Acta Academemiae Medicinae, [3rd Education Workshop of The Chinese Society for Neuroscience. Qingdao, China. 2009, 45: 191-192.
Chan Y.S., Chen L., Yung K.K.L. and Shum D.K.Y., Molecular and cellular aspects of plasticity after neural injury, Journal of Medical Sciences. 2008, 1(2): 73-79.
Chan Y.S., Neuroscience Research. 2009.
Cheah K.S.E., Au Y.K., Szeto Y.Y., Wynn S.L., Geng G.Y.H., Chan Y.S., Chan W.Y., Cheung K.M.C. and Fritzsch B., Illuminating the aetiology of Campomelic dysplasia caused by mutation in the transactivation domain of SOX9, Frontiers in Biomedical Research, Hong Kong December 12. 2008.
Cheah K.S.E., Au Y.K., Szeto Y.Y., Wynn S.L., Chan Y.S., Cheung K.M.C., Chan W.Y., Lovell-Badge R.H. and Fritzsch B., Insights into the function of SOX9 and campomelic dysplasia, American Society for Matrix Biology, 2008 Meeting, San Diego, California, USA, December 07-10. 2008.
Chen L., Yung K.K.L., Chan Y.S., Shum D.K.Y. and Bolam J.P., The proNGF-p75NTR-sortilin signalling complex as new target for the therapeutic treatment of Parkinson’s disease, CNS & Neurological Disorders - Drug Targets. 2008, 7: 512-523.
Chu K.H., Zhang M., Wong E.Y.M., Szeto Y.Y., Chan Y.S., Cheah K.S.E. and Sham M.H., Sox10 mutation affects inner ear gliogenesis and morphogenesis, The 7th Molecular Biology of Hearing and Deafness. Harvard Medical School. Boston, June 20-23, USA. 2009.
Chung E.K., Chen L., Chan Y.S. and Yung K.K.L., Downregulations of glial glutamate transporters after dopamine denervation in the striatum of 6-hydroxydopamine-lesioned rats, J. Comparative Neurology. 2008, 511: 421-437.
Fung C.K., Ao Q., Tsui Y.P., Shum D.K.Y. and Chan Y.S., Derivation of Schwann cells from mammalian skin and bone marrow for use in axonal regeneration, Soc. Neurosci. Abst. (USA), 327.13/C22. 2008.
Fung C.K., Ao Q., Tsui Y.P., Shum D.K.Y. and Chan Y.S., In vitro generation of Schwann cells from mammalian skin for bridging injured nerves, Proc. 6th Asian Biophysics Association Symposium. 2009, 161-162.
Gao J., Lee T.M.C., Chan Y.S., Chu L.W. and Cheung R.T.F., Different neural correlates of speed and accuracy in a choice response time task: a voxel based morphometric study on pathological and healthy aging, Fourth International Symposium on Healthy Aging: Emerging Therapies for an Aging Population, Research Centre of Heart, Brain, Hormone & Healthy Aging. 2009, 47.
Gao J., Chu L.W., Chan Y.S., Lee T.M.C. and Cheung R.T.F., Task interference of prospective memory in healthy ageing and Alzheimer’s disease: differential role of speed processing and response regulation, Hong Kong Medical Journal. 2009, 17.
Gao J., Lee T.M.C., Chan Y.S., Chu L.W. and Cheung R.T.F., The differential role of processing speed and response regulation in prospective memory interference in aging and dementia, Fourth International Symposium on Healthy Aging: Emerging Therapies for an Aging Population, Research Centre of Heart, Brain, Hormone & Healthy Aging. 2009, 65.
Han L., Lai S.K., Lai C.H. and Chan Y.S., Electrophysiological study of glutamatergic and GABAergic transmission in the inferior olive of postnatal rats, Proc. 6th Asian Biophysics Association Symposium, p. 168 . 2009.
Han L., Lai S.K., Lai C.H. and Chan Y.S., A comparative study of synaptic transmission of inferior olivary neurons of P7 and P14 rats , Abstracts of Fourth International Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 75 . 2009.
Han L., Lai S.K., Lai C.H. and Chan Y.S., In-vitro study of excitatory and inhibitory transmission in inferior olivary neurons of postnatal rats, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Han L., Lai S.K., Lai C.H. and Chan Y.S., Synaptic transmission in the inferior olivary neurons of postnatal rats, Abstracts of Physiology Symposium 2009: 28. Hong Kong, May 29-30. 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Development profile of GABAA-mediated synaptic transmission in medial vestibular neurons of rat, Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 76 . 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Developmental Changes OF GABAA –Mediated Miniature and Evoked Inhibitory Postsynaptic Currents in Medial Vestibular Nucleus Neurons of Rat, Abstracts of Physiology Symposium 2009: 30. Hong Kong, May 29-30. 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Developmental profile of GABAA receptor-mediated miniature postsynaptic currents in rat medial vestibular neurons, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Postnatal development of GABA transmission in medial vestibular nucleus neurons of rat, Proc. 6th Asian Biophysics Association Symposium, p. 162 . 2009.
Lai C.H., Ng K.Y., Yung K.K.L., Shum D.K.Y. and Chan Y.S., Co-expression of GABABR1and GABABR2 receptor subunits in rat vestibular nucleus, Neuroembryology and Aging. 2008, 5: 127-133.
Lai C.H., Ng K.Y., Yung K.K.L., Shum D.K.Y. and Chan Y.S., Coexpression of GABABR1 and GABABR2 Receptor Subunits in the Rat Vestibular Nucleus , Neuroembryology and Aging . 2008, 5: 127-133.
Lai S.K., Tse Y.C., Wong T.P., Yung W.H. and Chan Y.S., Contribution of AMPA and NMDA glutamate receptors to the development of rat vestibular nucleus, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 75. 2009.
Lai S.K., Lai C.H., Tse Y.C., Yung K.K.L., Shum D.K.Y. and Chan Y.S., Developmental maturation of ionotropic glutamate receptor subunits in rat vestibular nuclear neurons responsive to vertical linear acceleration, European Journal of Neuroscience. 2008, 11: 2157-2172.
Lai S.K., Lai C.H., Zhang F.X., Ma C.W., Shum D.K.Y. and Chan Y.S., Neural plasticity of otolith-related vestibular system, Acta Academiae Medicinae Sinicae. 2008, 30: 741-746.
Lau J.W.K., Zhang H.Q., Chan Y.S. and Yung K.K.L., Differential expression of GABA receptor subunits messenger ribonucleic acids and immunoreactivity in the rat neostriatum during postnatal development, Neuroembryology and Aging. 2008, 5: 100-115.
Lau Y.P., Lai C.H. and Chan Y.S., Developmental change in expression of gravity-related thalamic neurons in rats, Proc. 6th Asian Biophysics Association Symposium, p. 167. 2009.
Lau Y.P., Lai C.H. and Chan Y.S., Postnatal development of thalamic neurons in response to vertical sinusoidal linear acceleration, Abstracts of Physiology Symposium 2009: 33. Hong Kong, May 29-30. 2009.
Li M., Chan Y.S. and Shum D.K.Y., The Role of Chondroitin Sulfate Moieties on Cranial Motor Neuron Migration in the Developing Hindbrain of Rates, 13th Research Postgraduate Symposium, HKU. Hong Kong December 10 & 11. 2008.
Li M., Chan Y.S. and Shum D.K.Y., The expression of chondroitin sulfates in rat embryonic hindbrain and their roles on the lateral migration of trigeminal motor neurons, Proc. 6th Asian Biophysics Association Symposium. 2009, 143-144.
Li M., Chan Y.S. and Shum D.K.Y., The restrictive role of chondroitin sulfate moieties on the lateral migration of trigeminal motor neurons during hindbrain development in rats, Soc. Neuroscience Abstract (USA), 29.14/C57. [Washington DC. Nov. 15-19, 2008]. 2008.
Li M., Chan Y.S. and Shum D.K.Y., The role of chondroitin sulfate moieties on trigeminal motor neuron migration in embryonic rat hindbrain, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 80. 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Carbohydrate and core protein components of perineuronal net play differential roles in functional modifications of vestibular nuclear neurons in the rat, Abstracts of Physiology Symposium 2009: 38. Hong Kong, May 29-30. 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Changes in perineuronal net components correlate with functional modifications of vestibular nuclear neurons in rats, Soc. Neuroscience Abstract (U.S.A.). 2008, 169.6.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Differential involvement of perineuronal net components in functional modifications of vestibular nuclear neurons in the rat, Proc. 6th Asian Biophysics Association Symposium. 2009, 72.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Differential roles of perineuronal net components in functional modifications of rat vestibular nuclear neurons, Abstracts of Fourth International Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 76 . 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Overexpression of Hoxb3 affects inner ear neurogenesis, Proc. 6th Asian Biophysics Association Symposium, p. 72. 2009.
Ng K.P., Lai C.H. and Chan Y.S., Developmental profile of thalamic neurons responsive to rotational and translational head movements, Proc. 6th Asian Biophysics Association Symposium, pp. 162-163. 2009.
Ng K.P., Lau Y.P., Lai C.H. and Chan Y.S., Developmental responsiveness of vestibular related thalamic neurons to angular and linear head movements, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Ng K.P., Lai C.H., Shum D.K.Y. and Chan Y.S., Maturation profile of thalamic neurons responsive to rotational and translational motions, Soc. Neuroscience Abstract (U.S.A.). 2008, 169.13.
Ng K.P., Lai C.H. and Chan Y.S., Postnatal responsiveness of vestibular-related thalamic neurons to angular and linear head movements, Abstracts of Physiology Symposium 2009: 20. Hong Kong, May 29-30. 2009.
Shea G.K.H., Tsui Y.P., Chan Y.S. and Shum D.K.Y., Ex Vivo Generation of Myelinating Schwann-cell Like Cells from Bone Marrow-derived Neurospheres, 13th Research Postgraduate Symposium, Hong Kong, December 10 & 11. 2008.
Shea G.K.H., Tsui Y.P., Chan Y.S. and Shum D.K.Y., Ex vivo generation of myelinating Schwann-cell-like cells from bone marrow-derived neurospheres, Proc. 6th Asian Biophysics Association Symposium. 2009, 68-69.
Shea G.K.H., Tsui Y.P., Chan Y.S. and Shum D.K.Y., Ex vivo generation of myelinating Schwann-cell-like cells from bone marrow-derived neurospheres, Soc. Neurosci. Abst. (USA), 623.3/B30. 2008.
Sun X., Guo Y.P., Shum D.K.Y., Chan Y.S. and He J., Time course of cortically induced Fos expression in auditory thalamus and midbrain after bilateral cochlear ablation, Neuroscience. 2009, 60: 186-197.
Szeto Y.Y., Au Y.K., Wynn S., Chan Y.S., Lovell-Badge R., Chan W.Y., Fritzsch B. and Cheah K.S.E., Sensorineural Deafness in a mouse model of Campomelic Dysplasia, The 18th CDB Meeting, Common themes and New Concepts in Sensory Formation, RIKEN Center for Developmental Biology, April 13-16, Kobe, Japan . 2009.
Tam K.W., Li R.A., Chan Y.S. and Shum D.K.Y., Chondroitinase ABC isoforms cooperate to enhance axonal growth, Proc. 6th Asian Biophysics Association Symposium. 2009, 163-164.
Tam K.W., Li R.A., Chan Y.S. and Shum D.K.Y., Use of chondroitin sulphate exolyase and endolyase to decrease axon-restrictive chondroitin sulphates in neural environments, Soc. Neuroscience Abstract (U.S.A.), 651.2/AA19. 2008.
Tsui Y.P., Shea G.K.H., Ao Q., Chan Y.S. and Shum D.K.Y., Schwann cells derived from bone marrow stromal cells – in vitro study with dorsal root ganglia and in vivo study with peripheral nerve conduits. Neuroscience Research (Suppl 1): S, [31st Annual Meeting of Japan Neuroscience Society Tokyo. July 9-11, 2008 . 2008.
Wong E.Y.M., Fritzsch B., Wu D.K., Chan Y.S., Cheah K.S.E. and Sham M.H., Over-expression of Hoxb3 affects inner ear neurogenesis, The 27th Hong Kong Society of Neuroscience Annual Meeting, Hong Kong. 2008.
Zhang Z., Liu C.H., Yu Y.Q., Eujimoto K., Chan Y.S. and He J., Corticofugal projection inhibits the auditory thalamus through the thalamic reticular nucleus, Journal of Neurophysiology. 2008, 99: 2938-2945.


Researcher : Chen L

List of Research Outputs

Chan Y.S., Chen L., Yung K.K.L. and Shum D.K.Y., Molecular and cellular aspects of plasticity after neural injury, Journal of Medical Sciences. 2008, 1(2): 73-79.
Chen L., Yung K.K.L., Chan Y.S., Shum D.K.Y. and Bolam J.P., The proNGF-p75NTR-sortilin signalling complex as new target for the therapeutic treatment of Parkinson’s disease, CNS & Neurological Disorders - Drug Targets. 2008, 7: 512-523.
Chung E.K., Chen L., Chan Y.S. and Yung K.K.L., Downregulations of glial glutamate transporters after dopamine denervation in the striatum of 6-hydroxydopamine-lesioned rats, J. Comparative Neurology. 2008, 511: 421-437.


Researcher : Cho CH

List of Research Outputs

Li P., Wu K.K., Wong H.P.S., Zhang S.T., Yu L. and Cho C.H., Chloroform extract of cigarette smoke induces proliferation of human esophageal squamous-cell carcinoma cells: modulation by beta-adrenoceptors, Drug and Chemical Toxicology. 2009, 32: 175-181.


Researcher : Chung SSM

List of Research Outputs

Chan W.H., Ho Y.S., Chung S.K. and Chung S.S.M., Synergistic effect of osmotic and oxidative stress in slow-developing cataract formation, Experimental Eye Research. 2008, 87: 454-461.
Chung S.S.M., Synergistic Effect Of Osmotic And Oxidative Stress In Slow-developing Cataract, 18th International Congress Of Eye Research . 2008.
Fu Z., Li S.Y., Chung S.K., Chung S.S.M., Wong D.S.H. and Lo A.C.Y., Effect of aldose reductase in an animal model of retinopathy of prematurity, The 27th Hong Kong Society of Neuroscience Annual Meeting. 2009.
Fu Z., Li S.Y., Chung S.K., Chung S.S.M., Wong D.S.H. and Lo A.C.Y., Role of aldose reductase in mouse model of retinopathy of prematurity, Fourth International Symposium on Healthy Aging: "Emerging Therapies for an Aging Population". 2009.
Leung W.C., Chung S.S.M. and Chung S.K., Endothelial Endothelin-1 Over-expression Using Receptor Tyrosine Kinase Tei-1 Promoter Leads To More Severe Vascular Permeability And Blood Brainbarrier Breakdown After Transient Middle Crebral Artery Occlusion , Brain Research. 2009, 1266.
Liu Z., Zhong L., Krishack P.A., Robbins S., Cao J.X., Zhao Y., Chung S.S.M. and Cao D., Structure And Promoter Characterization Of Aldo-keto Reductase Family 1 B10 Gene, Gene. 2009, 437: 39-44.
Yeung C.M., Cheung K.H.A., Lo A.C.Y., Wong D.S.H., Chung S.S.M. and Chung S.K., Deletion of aldose reductase protects the diabetic db/db mouse from ischemic brain and retinal injuries, The 27th Hong Kong Society of Neuroscience Annual Meeting. 2009.


Researcher : Fung CK

List of Research Outputs

Ao Q., Fung C.K., Tsui Y.P., Chan Y.S. and Shum D.K.Y., Chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells enhance regeneration of transected sciatic nerves of adult rats, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 69. 2009.
Fung C.K., Ao Q., Tsui Y.P., Shum D.K.Y. and Chan Y.S., Derivation of Schwann cells from mammalian skin and bone marrow for use in axonal regeneration, Soc. Neurosci. Abst. (USA), 327.13/C22. 2008.
Fung C.K., Ao Q., Tsui Y.P., Shum D.K.Y. and Chan Y.S., In vitro generation of Schwann cells from mammalian skin for bridging injured nerves, Proc. 6th Asian Biophysics Association Symposium. 2009, 161-162.


Researcher : Fung ML

List of Research Outputs

Fung M.L., Newsletter Editor, Newsletter of Asia-Pacific Society for Mountain Medicine. 2008.
Fung M.L., Tjong Y.W., Hung M.W., Li M. and Lau C.F., Nitric Oxide Deficit in Sleep Apnea. XIV Biennial Meeting of the Society for Free Radical Research International, Beijing, China, (Progress in Biochemistry and Biophysics, 35(Suppl.) 210. 2008.
Fung M.L., Nitric Oxide Deficit in Sleep Apnea, XIV Biennial Meeting of the Society for Free Radical Research International. 2008.
Fung M.L., Roles of hypoxia-inducible factors and cytokine expression in the carotid body function at high altitude, 1st Congress of Asia-Pacific Society for Mountain Medicine. 2008.
Ho M.C.T., Tipoe G.L., Liong E.C., Leung T.M., Lau T.Y.H., Fung M.L. and Nanji A.A., Decreased adiponectin and antioxidant enzymes are associated with necroinflammatory changes and fibrosis in a rat model for non-alcoholic fatty liver disease (NAFLD)International Shanghai-HK Liver Meeting, Hepatology International. 2008, 2: S151-152.
Lam S.S.Y., Tipoe G.L., Liong E.C. and Fung M.L., Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body, Histochemistry and Cell Biology. 2008, 130(3): 549-559.
Lam S.S.Y., Tipoe G.L., Liong E.C. and Fung M.L., Functional upregulation of proinflammatory cytokines in the rat carotid body during chronic intermittent hypoxia. Beijing Joint Conference of Physiological Sciences 2008, Beijing, China, (Acta Physiologica Sinica, 60(Suppl.1):. 2008, 357-8.
Lam S.S.Y., Tipoe G.L. and Fung M.L., Upregulation of erythropoietin and its receptor expression in the rat carotid body during chronic and intermittent hypoxia, The 17th International Society for Arterial Chemoreception Meeting, Valladolid, Spain. 2008.
Lam S.Y.S., Tipoe G.L. and Fung M.L., Upregulation of erythropoietin and its receptor expression in the rat carotid body during chronic and intermittent hypoxia, In: C. Gonzalez, Advances in Experimental Medicine and Biology. Netherlands, Springer, 2009, 648: 207-214.
Leung T.M., Tipoe G.L., Liong E.C., Lau T.Y.H., Fung M.L. and Nanji A.A., Endothelial nitric oxide synthase is a critical factor in experimetnal liver fibrosis, International Journal of Experimental Pathology. 2008, 89: 241-250.
Leung T.M., Nanji A.A., Liong E.C., Lau T.Y.H., Fung M.L. and Tipoe G.L., Green Tea Polyphenols (GTPs) protect against liver fibrosis in mice. AALSD Meeting 2008, San Francisco USA, Suppl., 927A, Hepatology. 2008, 48 (4).
Lin R., Fung M.L. and Huang J., Reduced Neuronal Nitric Oxide Production from KIF5B-deficiency Mice, 13th Research Postgraduate Symposium, HKU December 10 & 11. 2008.
Lin R., Fung M.L. and Huang J., Reduced neuronal nitric oxide production from KIF5B-deficiency mice, 13th Research Postgraduate Symposium, HKU. 2008, P1.21.
Liu Y., Lau C.F., Ng K.M. and Fung M.L., Chronic hypoxia enhances nitric oxide production in rat adrenal gland, 13th Research Postgraduate Symposium, HKU. 2008, P1.23.
Liu Y., Lau C.F., Ng K.M. and Fung M.L., Up-regulation of endogenous nitric oxide production in rat adrenal gland in chronic hypoxia. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, Journal of the Hong Kong College of Cardiology. 2008, 16(2):73: P24.
Ng K.M., Lee Y.K., Fung M.L., Li R.A., Siu D.C.W., Siu D.C.W. and Tse H.F., Low oxygen tension promotes cardiac differentiation of human embryonic stem cells, The Forth International Symposium on Healthy Aging, HKU, Hong Kong. 2009.
Ng K.T., Li J.P., Ng K.M., Tipoe G.L., Leung W.K. and Fung M.L., Hypoxia Inducible Factor-1-alpha in Healthy and Diseased Periodontium. 22nd International Association for Dental Research (SEA Division), 19th South East Asia Association for Dental Education, Manile. 2008.
Shen J., Lee W.S., Li Y., Lau C.F., Ng K.M., Fung M.L. and Liu K.J., Interaction of caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells., Journal of Neurochemistry. 2008, 107: 478-487.
Tipoe G.L., Ho M.C.T., Liong E.C., Leung T.M., Lau T.Y.H., Fung M.L. and Nanji A.A., Green Tea Polyphenols (GTPs) Reduce Fibrogenesis in Non-Alcoholic Fatty Liver Disease in Rats. AALSD Meeting 2008, San Francisco USA , (Hepatology 841A, Suppl. 2008, 48 (4).
Tipoe G.L., Ho C.T., Liong E.C., Leung T.M., Lau T.Y.H., Fung M.L. and Nanji A.A., Green tea polyphenols (GTPS) reduced fibrogenesis in non-alcoholic fatty liver disease in rats, Hepatology. 2008, 48(4) Suppl: 841A 1195.
Tipoe G.L., Liong E.C., Lau K.S., Leung T.M., Leung K.M., Fung M.L. and Nanji A.A., Sex differences in acute liver injury in cyclooxygenase-1 deficient mice. AALSD Meeting 2008, San Francisco USA Suppl., 998A, Hepatology. 2008, 48(4).
Tipoe G.L., Ho C.T., Liong E.C., Leung T.M., Lau T.Y.H., Fung M.L. and Nanji A.A., Voluntary oral feeding of rats not requiring a very high diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD), Histology and Histopathology. 2009, 24: 1161-1169.
Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia aggravates oxidative stress and deteriorates calcium homeostasis in rat hearts, 13th Research Postgraduate Symposium, HKU. 2008, P1.19.
Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia elevates oxidative stress and impairs calcium homeostasis in rat cardiomyocytes. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, OC10, Journal of the Hong Kong College of Cardiology. 2008, 16(2): 61.
Yeung H.M., Hung M.W. and Fung M.L., Melatonin ameliorates calcium homeostasis in myocardial and ischemia-reperfusion injury in chronically hypoxic rats, Journal of Pineal Research. 2008, 45: 373-382.


Researcher : Han L

List of Research Outputs

Han L., Lai S.K., Lai C.H. and Chan Y.S., Electrophysiological study of glutamatergic and GABAergic transmission in the inferior olive of postnatal rats, Proc. 6th Asian Biophysics Association Symposium, p. 168 . 2009.
Han L., Lai S.K., Lai C.H. and Chan Y.S., A comparative study of synaptic transmission of inferior olivary neurons of P7 and P14 rats , Abstracts of Fourth International Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 75 . 2009.
Han L., Lai S.K., Lai C.H. and Chan Y.S., In-vitro study of excitatory and inhibitory transmission in inferior olivary neurons of postnatal rats, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Han L., Lai S.K., Lai C.H. and Chan Y.S., Synaptic transmission in the inferior olivary neurons of postnatal rats, Abstracts of Physiology Symposium 2009: 28. Hong Kong, May 29-30. 2009.


Researcher : Hao Q

List of Research Outputs

Hao Q., Structural study of Enzymatic Reaction Intermediates, HK Chemical Biology Symposium 2009. 2009.
Hao Q., Understanding protein function through structure, Physiology Symposium 2009, Hong Kong. 2009.
Hao Q., Using Molecular Envelope Information Derived from SAXS and EM for Crystallographic Phasing, Microscopy & Microanalysis 2008 Meeting, Albuquerque, USA. 2008.
Hong X. and Hao Q., Combining solution wide-angle X-ray scattering and crystallography: determination of molecular envelope and heavy-atom sites, Journal of Applied Crystallography. 2009, 42: 259-264.
Hong X. and Hao Q., High resolution pair-distance distribution function P(r) of protein solutions, Applied Physics Letters. 2009, 94: 083903.
Hong X. and Hao Q., Measurements of accurate x-ray scattering data of protein solutions using small stationary sample cells, Review of Scientific Instruments. 2009, 80: 014303.
Jiang H..., Congleton J..., Liu Q..., Merchant P...U..., Malavasi F..., Lee H.C., Hao Q., Yen A... and Lin H..., Mechanism-based small molecule probes for labeling CD38 on live cells., Journal of American Chemical Society. 2009, 131: 1658-1659.
Kotaka M., Zhang H., Graeff R., Liu Q., Kriksunov I.A., Oppenheimer N., Lee H.C. and Hao Q., Structural Basis for Enzymatic Mechanisms of ADP-ribosyl Cyclase , Physiology Symposium 2009.
Liu Q., Kriksunov I...A..., Jiang H., Graeff R., Lin H., Lee H.C. and Hao Q., Covalent and non-covalent intermediates of the calcium signaling enzyme CD38., Chemistry and Biology. 2008, 15: 1068-1078.
Liu Q., Kriksunov I...A..., Wang Z..., Graeff R..., Lee H.C. and Hao Q., Hierarchical and helical self-assembly of ADP-ribosyl cyclase into large-scale protein microtubes., Journal of Physical Chemistry B. 2008, 112: 14682-14686.
Liu Q..., Graeff R..., Kriksunov I...A..., Lam M.C., Lee H.C. and Hao Q., Conformational closure of the catalytic site of human CD38 induced by calcium., Biochemistry. 2008, 47: 13966-13973.


Researcher : Hu H

List of Research Outputs

Hu H., Lai S.K., Lai C.H. and Chan Y.S., Development profile of GABAA-mediated synaptic transmission in medial vestibular neurons of rat, Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 76 . 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Developmental Changes OF GABAA –Mediated Miniature and Evoked Inhibitory Postsynaptic Currents in Medial Vestibular Nucleus Neurons of Rat, Abstracts of Physiology Symposium 2009: 30. Hong Kong, May 29-30. 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Developmental profile of GABAA receptor-mediated miniature postsynaptic currents in rat medial vestibular neurons, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Postnatal development of GABA transmission in medial vestibular nucleus neurons of rat, Proc. 6th Asian Biophysics Association Symposium, p. 162 . 2009.


Researcher : Hung MW

List of Research Outputs

Fung M.L., Tjong Y.W., Hung M.W., Li M. and Lau C.F., Nitric Oxide Deficit in Sleep Apnea. XIV Biennial Meeting of the Society for Free Radical Research International, Beijing, China, (Progress in Biochemistry and Biophysics, 35(Suppl.) 210. 2008.
Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia aggravates oxidative stress and deteriorates calcium homeostasis in rat hearts, 13th Research Postgraduate Symposium, HKU. 2008, P1.19.
Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia elevates oxidative stress and impairs calcium homeostasis in rat cardiomyocytes. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, OC10, Journal of the Hong Kong College of Cardiology. 2008, 16(2): 61.
Yeung H.M., Hung M.W. and Fung M.L., Melatonin ameliorates calcium homeostasis in myocardial and ischemia-reperfusion injury in chronically hypoxic rats, Journal of Pineal Research. 2008, 45: 373-382.


Researcher : Kotaka M

List of Research Outputs

Kotaka M., Zhang H., Graeff R., Liu Q., Kriksunov I.A., Oppenheimer N., Lee H.C. and Hao Q., Structural Basis for Enzymatic Mechanisms of ADP-ribosyl Cyclase , Physiology Symposium 2009.


Researcher : Kravtsov GM

List of Research Outputs

Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia aggravates oxidative stress and deteriorates calcium homeostasis in rat hearts, 13th Research Postgraduate Symposium, HKU. 2008, P1.19.
Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia elevates oxidative stress and impairs calcium homeostasis in rat cardiomyocytes. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, OC10, Journal of the Hong Kong College of Cardiology. 2008, 16(2): 61.


Researcher : Lai CH

List of Research Outputs

Chan Y.S., Lai C.H., Lai S.K., Ma C.W. and Ng K.P., Developmental refinement of central vestibular pathway towards spatial recognition. , Acta Physiologica Sinica, 60 Suppl: 12. [Beijing Joint Conference of Physiological Sciences 2008. Beijing. Oct. 19-22, 2008] . 2008.
Han L., Lai S.K., Lai C.H. and Chan Y.S., Electrophysiological study of glutamatergic and GABAergic transmission in the inferior olive of postnatal rats, Proc. 6th Asian Biophysics Association Symposium, p. 168 . 2009.
Han L., Lai S.K., Lai C.H. and Chan Y.S., A comparative study of synaptic transmission of inferior olivary neurons of P7 and P14 rats , Abstracts of Fourth International Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 75 . 2009.
Han L., Lai S.K., Lai C.H. and Chan Y.S., In-vitro study of excitatory and inhibitory transmission in inferior olivary neurons of postnatal rats, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Han L., Lai S.K., Lai C.H. and Chan Y.S., Synaptic transmission in the inferior olivary neurons of postnatal rats, Abstracts of Physiology Symposium 2009: 28. Hong Kong, May 29-30. 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Development profile of GABAA-mediated synaptic transmission in medial vestibular neurons of rat, Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 76 . 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Developmental Changes OF GABAA –Mediated Miniature and Evoked Inhibitory Postsynaptic Currents in Medial Vestibular Nucleus Neurons of Rat, Abstracts of Physiology Symposium 2009: 30. Hong Kong, May 29-30. 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Developmental profile of GABAA receptor-mediated miniature postsynaptic currents in rat medial vestibular neurons, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Postnatal development of GABA transmission in medial vestibular nucleus neurons of rat, Proc. 6th Asian Biophysics Association Symposium, p. 162 . 2009.
Lai C.H., Ng K.Y., Yung K.K.L., Shum D.K.Y. and Chan Y.S., Co-expression of GABABR1and GABABR2 receptor subunits in rat vestibular nucleus, Neuroembryology and Aging. 2008, 5: 127-133.
Lai C.H., Ng K.Y., Yung K.K.L., Shum D.K.Y. and Chan Y.S., Coexpression of GABABR1 and GABABR2 Receptor Subunits in the Rat Vestibular Nucleus , Neuroembryology and Aging . 2008, 5: 127-133.
Lai S.K., Lai C.H., Tse Y.C., Yung K.K.L., Shum D.K.Y. and Chan Y.S., Developmental maturation of ionotropic glutamate receptor subunits in rat vestibular nuclear neurons responsive to vertical linear acceleration, European Journal of Neuroscience. 2008, 11: 2157-2172.
Lai S.K., Lai C.H., Zhang F.X., Ma C.W., Shum D.K.Y. and Chan Y.S., Neural plasticity of otolith-related vestibular system, Acta Academiae Medicinae Sinicae. 2008, 30: 741-746.
Lau Y.P., Lai C.H. and Chan Y.S., Developmental change in expression of gravity-related thalamic neurons in rats, Proc. 6th Asian Biophysics Association Symposium, p. 167. 2009.
Lau Y.P., Lai C.H. and Chan Y.S., Postnatal development of thalamic neurons in response to vertical sinusoidal linear acceleration, Abstracts of Physiology Symposium 2009: 33. Hong Kong, May 29-30. 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Carbohydrate and core protein components of perineuronal net play differential roles in functional modifications of vestibular nuclear neurons in the rat, Abstracts of Physiology Symposium 2009: 38. Hong Kong, May 29-30. 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Changes in perineuronal net components correlate with functional modifications of vestibular nuclear neurons in rats, Soc. Neuroscience Abstract (U.S.A.). 2008, 169.6.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Differential involvement of perineuronal net components in functional modifications of vestibular nuclear neurons in the rat, Proc. 6th Asian Biophysics Association Symposium. 2009, 72.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Differential roles of perineuronal net components in functional modifications of rat vestibular nuclear neurons, Abstracts of Fourth International Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 76 . 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Overexpression of Hoxb3 affects inner ear neurogenesis, Proc. 6th Asian Biophysics Association Symposium, p. 72. 2009.
Ng K.P., Lai C.H. and Chan Y.S., Developmental profile of thalamic neurons responsive to rotational and translational head movements, Proc. 6th Asian Biophysics Association Symposium, pp. 162-163. 2009.
Ng K.P., Lau Y.P., Lai C.H. and Chan Y.S., Developmental responsiveness of vestibular related thalamic neurons to angular and linear head movements, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Ng K.P., Lai C.H., Shum D.K.Y. and Chan Y.S., Maturation profile of thalamic neurons responsive to rotational and translational motions, Soc. Neuroscience Abstract (U.S.A.). 2008, 169.13.
Ng K.P., Lai C.H. and Chan Y.S., Postnatal responsiveness of vestibular-related thalamic neurons to angular and linear head movements, Abstracts of Physiology Symposium 2009: 20. Hong Kong, May 29-30. 2009.


Researcher : Lai SK

List of Research Outputs

Chan Y.S., Lai C.H., Lai S.K., Ma C.W. and Ng K.P., Developmental refinement of central vestibular pathway towards spatial recognition. , Acta Physiologica Sinica, 60 Suppl: 12. [Beijing Joint Conference of Physiological Sciences 2008. Beijing. Oct. 19-22, 2008] . 2008.
Han L., Lai S.K., Lai C.H. and Chan Y.S., Electrophysiological study of glutamatergic and GABAergic transmission in the inferior olive of postnatal rats, Proc. 6th Asian Biophysics Association Symposium, p. 168 . 2009.
Han L., Lai S.K., Lai C.H. and Chan Y.S., A comparative study of synaptic transmission of inferior olivary neurons of P7 and P14 rats , Abstracts of Fourth International Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 75 . 2009.
Han L., Lai S.K., Lai C.H. and Chan Y.S., In-vitro study of excitatory and inhibitory transmission in inferior olivary neurons of postnatal rats, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Han L., Lai S.K., Lai C.H. and Chan Y.S., Synaptic transmission in the inferior olivary neurons of postnatal rats, Abstracts of Physiology Symposium 2009: 28. Hong Kong, May 29-30. 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Development profile of GABAA-mediated synaptic transmission in medial vestibular neurons of rat, Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 76 . 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Developmental Changes OF GABAA –Mediated Miniature and Evoked Inhibitory Postsynaptic Currents in Medial Vestibular Nucleus Neurons of Rat, Abstracts of Physiology Symposium 2009: 30. Hong Kong, May 29-30. 2009.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Developmental profile of GABAA receptor-mediated miniature postsynaptic currents in rat medial vestibular neurons, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Hu H., Lai S.K., Lai C.H. and Chan Y.S., Postnatal development of GABA transmission in medial vestibular nucleus neurons of rat, Proc. 6th Asian Biophysics Association Symposium, p. 162 . 2009.
Lai S.K., Tse Y.C., Wong T.P., Yung W.H. and Chan Y.S., Contribution of AMPA and NMDA glutamate receptors to the development of rat vestibular nucleus, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 75. 2009.
Lai S.K., Lai C.H., Tse Y.C., Yung K.K.L., Shum D.K.Y. and Chan Y.S., Developmental maturation of ionotropic glutamate receptor subunits in rat vestibular nuclear neurons responsive to vertical linear acceleration, European Journal of Neuroscience. 2008, 11: 2157-2172.
Lai S.K., Lai C.H., Zhang F.X., Ma C.W., Shum D.K.Y. and Chan Y.S., Neural plasticity of otolith-related vestibular system, Acta Academiae Medicinae Sinicae. 2008, 30: 741-746.


Researcher : Lam MC

List of Research Outputs

Lam M.C., Yeung P.K.K., Lee H.C. and Wong J.T.Y., Cyclic ADP-ribose links metabolism to multiple fission in the dinoflagellate Crypthecodinium cohnii., Cell Calcium. 2009, 45: 346-357.
Lam M.C., Molecular Topology of CD38, NAD2008: Emerging roles of NAD & NAD-metabolities in cell signaling , Hamburg, Germany, Sept 14-17, 2008. 2008.
Liu Q..., Graeff R..., Kriksunov I...A..., Lam M.C., Lee H.C. and Hao Q., Conformational closure of the catalytic site of human CD38 induced by calcium., Biochemistry. 2008, 47: 13966-13973.
Yue J., Lam M.C., Zhao Y. and Lee H.C., Exploring the function and mechanism of CD38/cADPR-mediated calcium signaling in neurosecretory PC12 cells , NAD2008: Emerging roles of NAD & NAD-metabolities in cell signaling, Hamburg, Germany, Sept 14-17, 2008.


Researcher : Lam SSY

List of Research Outputs

Lam S.S.Y., Tipoe G.L., Liong E.C. and Fung M.L., Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body, Histochemistry and Cell Biology. 2008, 130(3): 549-559.
Lam S.S.Y., Tipoe G.L., Liong E.C. and Fung M.L., Functional upregulation of proinflammatory cytokines in the rat carotid body during chronic intermittent hypoxia. Beijing Joint Conference of Physiological Sciences 2008, Beijing, China, (Acta Physiologica Sinica, 60(Suppl.1):. 2008, 357-8.
Lam S.S.Y., Tipoe G.L. and Fung M.L., Upregulation of erythropoietin and its receptor expression in the rat carotid body during chronic and intermittent hypoxia, The 17th International Society for Arterial Chemoreception Meeting, Valladolid, Spain. 2008.


Researcher : Lam SYS

List of Research Outputs

Lam S.Y.S., Tipoe G.L. and Fung M.L., Upregulation of erythropoietin and its receptor expression in the rat carotid body during chronic and intermittent hypoxia, In: C. Gonzalez, Advances in Experimental Medicine and Biology. Netherlands, Springer, 2009, 648: 207-214.


Researcher : Lau CF

List of Research Outputs

Fung M.L., Tjong Y.W., Hung M.W., Li M. and Lau C.F., Nitric Oxide Deficit in Sleep Apnea. XIV Biennial Meeting of the Society for Free Radical Research International, Beijing, China, (Progress in Biochemistry and Biophysics, 35(Suppl.) 210. 2008.
Liu Y., Lau C.F., Ng K.M. and Fung M.L., Chronic hypoxia enhances nitric oxide production in rat adrenal gland, 13th Research Postgraduate Symposium, HKU. 2008, P1.23.
Liu Y., Lau C.F., Ng K.M. and Fung M.L., Up-regulation of endogenous nitric oxide production in rat adrenal gland in chronic hypoxia. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, Journal of the Hong Kong College of Cardiology. 2008, 16(2):73: P24.
Shen J., Lee W.S., Li Y., Lau C.F., Ng K.M., Fung M.L. and Liu K.J., Interaction of caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells., Journal of Neurochemistry. 2008, 107: 478-487.


Researcher : Lau JWK

List of Research Outputs

Lau J.W.K., Zhang H.Q., Chan Y.S. and Yung K.K.L., Differential expression of GABA receptor subunits messenger ribonucleic acids and immunoreactivity in the rat neostriatum during postnatal development, Neuroembryology and Aging. 2008, 5: 100-115.


Researcher : Lau YP

List of Research Outputs

Lau Y.P., Lai C.H. and Chan Y.S., Developmental change in expression of gravity-related thalamic neurons in rats, Proc. 6th Asian Biophysics Association Symposium, p. 167. 2009.
Lau Y.P., Lai C.H. and Chan Y.S., Postnatal development of thalamic neurons in response to vertical sinusoidal linear acceleration, Abstracts of Physiology Symposium 2009: 33. Hong Kong, May 29-30. 2009.
Ng K.P., Lau Y.P., Lai C.H. and Chan Y.S., Developmental responsiveness of vestibular related thalamic neurons to angular and linear head movements, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.


Researcher : Lee HC

List of Research Outputs

Bezin S., Charpentier G., Lee H.C., Baux G., Fossier P. and Cancela J...-.M., Regulation of nuclear Ca2+ signalling by translocation of the Ca2+ messenger synthesizing enzyme ADP-ribosyl cyclase during neuronal depolarization., Journal of Biological Chemistry . 2008, 283: 27859- 27870.
Davis L...C..., Morgan A...J..., Ruas M..., Wong J...L..., Graeff R...M..., Poustka A...J..., Lee H.C., Wessel G...M..., Parrington J... and Galione A..., Ca2+ signalling via second messenger release from intra-organelle synthesis sites., Current Biology. 2008, 18: 1612-1618.
Guse A...H... and Lee H.C., NAADP: A universal Ca2+ trigger, Science Signaling (http://stke.sciencemag.org/cgi/reprint/sigtrans;1/44/re10.pdf). 2008, 1: re10.
Jiang H..., Congleton J..., Liu Q..., Merchant P...U..., Malavasi F..., Lee H.C., Hao Q., Yen A... and Lin H..., Mechanism-based small molecule probes for labeling CD38 on live cells., Journal of American Chemical Society. 2009, 131: 1658-1659.
Kotaka M., Zhang H., Graeff R., Liu Q., Kriksunov I.A., Oppenheimer N., Lee H.C. and Hao Q., Structural Basis for Enzymatic Mechanisms of ADP-ribosyl Cyclase , Physiology Symposium 2009.
Lam M.C., Yeung P.K.K., Lee H.C. and Wong J.T.Y., Cyclic ADP-ribose links metabolism to multiple fission in the dinoflagellate Crypthecodinium cohnii., Cell Calcium. 2009, 45: 346-357.
Liu Q., Kriksunov I...A..., Jiang H., Graeff R., Lin H., Lee H.C. and Hao Q., Covalent and non-covalent intermediates of the calcium signaling enzyme CD38., Chemistry and Biology. 2008, 15: 1068-1078.
Liu Q., Kriksunov I...A..., Wang Z..., Graeff R..., Lee H.C. and Hao Q., Hierarchical and helical self-assembly of ADP-ribosyl cyclase into large-scale protein microtubes., Journal of Physical Chemistry B. 2008, 112: 14682-14686.
Liu Q..., Graeff R..., Kriksunov I...A..., Lam M.C., Lee H.C. and Hao Q., Conformational closure of the catalytic site of human CD38 induced by calcium., Biochemistry. 2008, 47: 13966-13973.
Yue J., Lam M.C., Zhao Y. and Lee H.C., Exploring the function and mechanism of CD38/cADPR-mediated calcium signaling in neurosecretory PC12 cells , NAD2008: Emerging roles of NAD & NAD-metabolities in cell signaling, Hamburg, Germany, Sept 14-17, 2008.


Researcher : Leung WK

List of Research Outputs

Ng K.T., Li J.P., Ng K.M., Tipoe G.L., Leung W.K. and Fung M.L., Hypoxia Inducible Factor-1-alpha in Healthy and Diseased Periodontium. 22nd International Association for Dental Research (SEA Division), 19th South East Asia Association for Dental Education, Manile. 2008.


Researcher : Li M

List of Research Outputs

Fung M.L., Tjong Y.W., Hung M.W., Li M. and Lau C.F., Nitric Oxide Deficit in Sleep Apnea. XIV Biennial Meeting of the Society for Free Radical Research International, Beijing, China, (Progress in Biochemistry and Biophysics, 35(Suppl.) 210. 2008.


Researcher : Liu Y

List of Research Outputs

Liu Y., Lau C.F., Ng K.M. and Fung M.L., Chronic hypoxia enhances nitric oxide production in rat adrenal gland, 13th Research Postgraduate Symposium, HKU. 2008, P1.23.
Liu Y., Lau C.F., Ng K.M. and Fung M.L., Up-regulation of endogenous nitric oxide production in rat adrenal gland in chronic hypoxia. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, Journal of the Hong Kong College of Cardiology. 2008, 16(2):73: P24.


Researcher : Ma CW

List of Research Outputs

Cham W.C., Ma C.W., Zhang Y., Xie H., Yung W.H., Chan Y.S. and Shum D.K.Y., Heparanase modulates synaptic plasticity at the hippocampus, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 77. 2009.
Cham W.C., Ma C.W., Zhang Y., Chan Y.S. and Shum D.K.Y., Role of heparanase in synaptic plasticity at the hippocampus and the vestibular nucleus, Proc. 6th Asian Biophysics Association Symposium. 2009, 167-168.
Chan Y.S., Lai C.H., Lai S.K., Ma C.W. and Ng K.P., Developmental refinement of central vestibular pathway towards spatial recognition. , Acta Physiologica Sinica, 60 Suppl: 12. [Beijing Joint Conference of Physiological Sciences 2008. Beijing. Oct. 19-22, 2008] . 2008.
Lai S.K., Lai C.H., Zhang F.X., Ma C.W., Shum D.K.Y. and Chan Y.S., Neural plasticity of otolith-related vestibular system, Acta Academiae Medicinae Sinicae. 2008, 30: 741-746.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Carbohydrate and core protein components of perineuronal net play differential roles in functional modifications of vestibular nuclear neurons in the rat, Abstracts of Physiology Symposium 2009: 38. Hong Kong, May 29-30. 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Changes in perineuronal net components correlate with functional modifications of vestibular nuclear neurons in rats, Soc. Neuroscience Abstract (U.S.A.). 2008, 169.6.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Differential involvement of perineuronal net components in functional modifications of vestibular nuclear neurons in the rat, Proc. 6th Asian Biophysics Association Symposium. 2009, 72.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Differential roles of perineuronal net components in functional modifications of rat vestibular nuclear neurons, Abstracts of Fourth International Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 76 . 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Overexpression of Hoxb3 affects inner ear neurogenesis, Proc. 6th Asian Biophysics Association Symposium, p. 72. 2009.


Researcher : Ma CW

List of Research Outputs

Cham W.C., Ma C.W., Zhang Y., Xie H., Yung W.H., Chan Y.S. and Shum D.K.Y., Heparanase modulates synaptic plasticity at the hippocampus, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 77. 2009.
Cham W.C., Ma C.W., Zhang Y., Chan Y.S. and Shum D.K.Y., Role of heparanase in synaptic plasticity at the hippocampus and the vestibular nucleus, Proc. 6th Asian Biophysics Association Symposium. 2009, 167-168.
Chan Y.S., Lai C.H., Lai S.K., Ma C.W. and Ng K.P., Developmental refinement of central vestibular pathway towards spatial recognition. , Acta Physiologica Sinica, 60 Suppl: 12. [Beijing Joint Conference of Physiological Sciences 2008. Beijing. Oct. 19-22, 2008] . 2008.
Lai S.K., Lai C.H., Zhang F.X., Ma C.W., Shum D.K.Y. and Chan Y.S., Neural plasticity of otolith-related vestibular system, Acta Academiae Medicinae Sinicae. 2008, 30: 741-746.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Carbohydrate and core protein components of perineuronal net play differential roles in functional modifications of vestibular nuclear neurons in the rat, Abstracts of Physiology Symposium 2009: 38. Hong Kong, May 29-30. 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Changes in perineuronal net components correlate with functional modifications of vestibular nuclear neurons in rats, Soc. Neuroscience Abstract (U.S.A.). 2008, 169.6.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Differential involvement of perineuronal net components in functional modifications of vestibular nuclear neurons in the rat, Proc. 6th Asian Biophysics Association Symposium. 2009, 72.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Differential roles of perineuronal net components in functional modifications of rat vestibular nuclear neurons, Abstracts of Fourth International Symposium on Healthy Aging: Emerging Therapy for an Aging Population: 76 . 2009.
Ma C.W., Lai C.H., Shum D.K.Y. and Chan Y.S., Overexpression of Hoxb3 affects inner ear neurogenesis, Proc. 6th Asian Biophysics Association Symposium, p. 72. 2009.


Researcher : Ng KM

List of Research Outputs

Au K.W., Liao S., Lee Y.K., Lai K.W.H., Ng K.M., Chan Y.C., Yip P.M.C., Ho J.C.Y., Wu E.X., Li R.A., Siu D.C.W. and Tse H.F., Effects of iron oxide nanoparticles on cardiac differentiation of embryonic stem cells, Biochem Biophys Res Commun. 2009, 379: 898-903.
Liu Y., Lau C.F., Ng K.M. and Fung M.L., Chronic hypoxia enhances nitric oxide production in rat adrenal gland, 13th Research Postgraduate Symposium, HKU. 2008, P1.23.
Liu Y., Lau C.F., Ng K.M. and Fung M.L., Up-regulation of endogenous nitric oxide production in rat adrenal gland in chronic hypoxia. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, Journal of the Hong Kong College of Cardiology. 2008, 16(2):73: P24.
Ng K.M., Lee Y.K., Fung M.L., Li R.A., Siu D.C.W., Siu D.C.W. and Tse H.F., Low oxygen tension promotes cardiac differentiation of human embryonic stem cells, The Forth International Symposium on Healthy Aging, HKU, Hong Kong. 2009.
Ng K.T., Li J.P., Ng K.M., Tipoe G.L., Leung W.K. and Fung M.L., Hypoxia Inducible Factor-1-alpha in Healthy and Diseased Periodontium. 22nd International Association for Dental Research (SEA Division), 19th South East Asia Association for Dental Education, Manile. 2008.
Shen J., Lee W.S., Li Y., Lau C.F., Ng K.M., Fung M.L. and Liu K.J., Interaction of caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells., Journal of Neurochemistry. 2008, 107: 478-487.


Researcher : Ng KP

List of Research Outputs

Chan Y.S., Lai C.H., Lai S.K., Ma C.W. and Ng K.P., Developmental refinement of central vestibular pathway towards spatial recognition. , Acta Physiologica Sinica, 60 Suppl: 12. [Beijing Joint Conference of Physiological Sciences 2008. Beijing. Oct. 19-22, 2008] . 2008.
Ng K.P., Lai C.H. and Chan Y.S., Developmental profile of thalamic neurons responsive to rotational and translational head movements, Proc. 6th Asian Biophysics Association Symposium, pp. 162-163. 2009.
Ng K.P., Lau Y.P., Lai C.H. and Chan Y.S., Developmental responsiveness of vestibular related thalamic neurons to angular and linear head movements, 13th Research Postgraduate Symposium, 10 Dec. 2008. The University of Hong Kong, Li Ka Shing Faculty of Medicine, 2008 . 2008.
Ng K.P., Lai C.H., Shum D.K.Y. and Chan Y.S., Maturation profile of thalamic neurons responsive to rotational and translational motions, Soc. Neuroscience Abstract (U.S.A.). 2008, 169.13.
Ng K.P., Lai C.H. and Chan Y.S., Postnatal responsiveness of vestibular-related thalamic neurons to angular and linear head movements, Abstracts of Physiology Symposium 2009: 20. Hong Kong, May 29-30. 2009.


Researcher : Pang B

List of Research Outputs

Pang B., Yao K.M. and Shiu S.Y.W., Potential signaling mechanisms of the secreted PDZ domain-containing protein 2 (sPDZD2) in tumor suppression, Annals of Oncology, Vol 20, Suppl. 3. 2009, 20: p29.
Tam C.W., Chan K.W., Liu V.W.S., Pang B., Yao K.M. and Shiu S.Y.W., Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance, Journal of Pineal Research. 2008, 45: 403-412.


Researcher : Shiu SYW

List of Research Outputs

Pang B., Yao K.M. and Shiu S.Y.W., Potential signaling mechanisms of the secreted PDZ domain-containing protein 2 (sPDZD2) in tumor suppression, Annals of Oncology, Vol 20, Suppl. 3. 2009, 20: p29.
Shiu S.Y.W., Melatonin signaling in prostate cancer antiproliferation, FASEB Summer Research Conferences- Melatonin Receptors: Actions and Therapeutics, Snowmass, Colorado, USA. 2008.
Tam C.W., Chan K.W., Liu V.W.S., Pang B., Yao K.M. and Shiu S.Y.W., Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance, Journal of Pineal Research. 2008, 45: 403-412.
Tam C.W., Yao K.M. and Shiu S.Y.W., Putative cellular receptor for secreted PDZ domain-containing protein 2 (sPDZD2) in cancer cells, Physiology Symposium 2009: Physiology from protein structure to function, Department of Physiology, The University of Hong Kong, May 29-30. Hong Kong, 2009, p17.
Tam C.W., Liu V.W.S., Leung W.Y., Yao K.M. and Shiu S.Y.W., The autocrine human secreted PDZ domain-containing protein 2 (sPDZD2) induces senescence or quiescence of prostate, breast and liver cancer cells via transcriptional activation of p53, Cancer Letters. 2008, 271: 64-80.


Researcher : Tam CW

List of Research Outputs

Tam C.W., Chan K.W., Liu V.W.S., Pang B., Yao K.M. and Shiu S.Y.W., Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance, Journal of Pineal Research. 2008, 45: 403-412.
Tam C.W., Yao K.M. and Shiu S.Y.W., Putative cellular receptor for secreted PDZ domain-containing protein 2 (sPDZD2) in cancer cells, Physiology Symposium 2009: Physiology from protein structure to function, Department of Physiology, The University of Hong Kong, May 29-30. Hong Kong, 2009, p17.
Tam C.W., Liu V.W.S., Leung W.Y., Yao K.M. and Shiu S.Y.W., The autocrine human secreted PDZ domain-containing protein 2 (sPDZD2) induces senescence or quiescence of prostate, breast and liver cancer cells via transcriptional activation of p53, Cancer Letters. 2008, 271: 64-80.


Researcher : Tam CW

List of Research Outputs

Tam C.W., Chan K.W., Liu V.W.S., Pang B., Yao K.M. and Shiu S.Y.W., Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance, Journal of Pineal Research. 2008, 45: 403-412.
Tam C.W., Yao K.M. and Shiu S.Y.W., Putative cellular receptor for secreted PDZ domain-containing protein 2 (sPDZD2) in cancer cells, Physiology Symposium 2009: Physiology from protein structure to function, Department of Physiology, The University of Hong Kong, May 29-30. Hong Kong, 2009, p17.
Tam C.W., Liu V.W.S., Leung W.Y., Yao K.M. and Shiu S.Y.W., The autocrine human secreted PDZ domain-containing protein 2 (sPDZD2) induces senescence or quiescence of prostate, breast and liver cancer cells via transcriptional activation of p53, Cancer Letters. 2008, 271: 64-80.


Researcher : Tam KW

List of Research Outputs

Tam K.W., Li R.A., Chan Y.S. and Shum D.K.Y., Chondroitinase ABC isoforms cooperate to enhance axonal growth, Proc. 6th Asian Biophysics Association Symposium. 2009, 163-164.
Tam K.W., Li R.A., Chan Y.S. and Shum D.K.Y., Use of chondroitin sulphate exolyase and endolyase to decrease axon-restrictive chondroitin sulphates in neural environments, Soc. Neuroscience Abstract (U.S.A.), 651.2/AA19. 2008.


Researcher : Tang F

List of Research Outputs

Chiu C.N., Chung M.K., Lam K.W., Lee C.L., Lee C.K.F., Yeung W.S.B., Tang F. and Ho P.C., The effect of adrenomedullin on the motility of human spermatozoa., P-07. The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 30 Nov, Hong Kong.. 2008.


Researcher : Tjong YW

List of Research Outputs

Fung M.L., Tjong Y.W., Hung M.W., Li M. and Lau C.F., Nitric Oxide Deficit in Sleep Apnea. XIV Biennial Meeting of the Society for Free Radical Research International, Beijing, China, (Progress in Biochemistry and Biophysics, 35(Suppl.) 210. 2008.


Researcher : Tse YC

List of Research Outputs

Lai S.K., Tse Y.C., Wong T.P., Yung W.H. and Chan Y.S., Contribution of AMPA and NMDA glutamate receptors to the development of rat vestibular nucleus, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 75. 2009.
Lai S.K., Lai C.H., Tse Y.C., Yung K.K.L., Shum D.K.Y. and Chan Y.S., Developmental maturation of ionotropic glutamate receptor subunits in rat vestibular nuclear neurons responsive to vertical linear acceleration, European Journal of Neuroscience. 2008, 11: 2157-2172.


Researcher : Wong TM

List of Research Outputs

Li R., Wong G.T.C., Wong T.M., Zhang Y., Xia Z. and Irwin M.G., Intrathecal morphine preconditioning induces cardioprotection via activation of μ, δ and κ- opioid receptors in rats, Anesthesia and Analgesia. 2008, 108(1): 23-29.
Zhou Y., Wong T.M. and Li G.R., Cardiac toxicity of chloroform: implication of multople ion channel inhibition., CardioRhythm 2009. Hong Kong.. 2009, i49.
Zhou Y., Wong T.M. and Li G.R., Ionic mechanisms of chloroform cardiac toxicity, 13th Research postgraduate symposium, HKU. 2008, 68.
Zhou Y., Wong T.M. and Li G.R., Multiple Ion Channel Block of Chloroform is Involved in its Arrhythmogenic Effect, J HK Coll Cardiol. 2008, 16(2): 68.


Researcher : Xie H

List of Research Outputs

Cham W.C., Ma C.W., Zhang Y., Xie H., Yung W.H., Chan Y.S. and Shum D.K.Y., Heparanase modulates synaptic plasticity at the hippocampus, Abstracts of 4th Int’l Symp. on Healthy Aging: Emerging Therapy for an Aging Population: 77. 2009.


Researcher : Yeung HM

List of Research Outputs

Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia aggravates oxidative stress and deteriorates calcium homeostasis in rat hearts, 13th Research Postgraduate Symposium, HKU. 2008, P1.19.
Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia elevates oxidative stress and impairs calcium homeostasis in rat cardiomyocytes. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, OC10, Journal of the Hong Kong College of Cardiology. 2008, 16(2): 61.
Yeung H.M., Hung M.W. and Fung M.L., Melatonin ameliorates calcium homeostasis in myocardial and ischemia-reperfusion injury in chronically hypoxic rats, Journal of Pineal Research. 2008, 45: 373-382.


Researcher : Yeung HM

List of Research Outputs

Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia aggravates oxidative stress and deteriorates calcium homeostasis in rat hearts, 13th Research Postgraduate Symposium, HKU. 2008, P1.19.
Yeung H.M., Hung M.W., Kravtsov G.M. and Fung M.L., Chronic intermittent hypoxia elevates oxidative stress and impairs calcium homeostasis in rat cardiomyocytes. The 12th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine, OC10, Journal of the Hong Kong College of Cardiology. 2008, 16(2): 61.
Yeung H.M., Hung M.W. and Fung M.L., Melatonin ameliorates calcium homeostasis in myocardial and ischemia-reperfusion injury in chronically hypoxic rats, Journal of Pineal Research. 2008, 45: 373-382.


Researcher : Yue J

List of Research Outputs

Yue J., Lam M.C., Zhao Y. and Lee H.C., Exploring the function and mechanism of CD38/cADPR-mediated calcium signaling in neurosecretory PC12 cells , NAD2008: Emerging roles of NAD & NAD-metabolities in cell signaling, Hamburg, Germany, Sept 14-17, 2008.


Researcher : Zhang H

List of Research Outputs

Kotaka M., Zhang H., Graeff R., Liu Q., Kriksunov I.A., Oppenheimer N., Lee H.C. and Hao Q., Structural Basis for Enzymatic Mechanisms of ADP-ribosyl Cyclase , Physiology Symposium 2009.


Researcher : Zhao Y

List of Research Outputs

Yue J., Lam M.C., Zhao Y. and Lee H.C., Exploring the function and mechanism of CD38/cADPR-mediated calcium signaling in neurosecretory PC12 cells , NAD2008: Emerging roles of NAD & NAD-metabolities in cell signaling, Hamburg, Germany, Sept 14-17, 2008.


Researcher : Zhou Y

List of Research Outputs

He M., Zhou Y., Lau C.P., Tse H.F. and Li G.R., Involvement of Ion Channels in Proliferation of Human Cardiac Fibroblasts , J HK Coll Cardiol. 2008, 16(2): 69.
Zhou Y., Wong T.M. and Li G.R., Cardiac toxicity of chloroform: implication of multople ion channel inhibition., CardioRhythm 2009. Hong Kong.. 2009, i49.
Zhou Y., Wong T.M. and Li G.R., Ionic mechanisms of chloroform cardiac toxicity, 13th Research postgraduate symposium, HKU. 2008, 68.
Zhou Y., Wong T.M. and Li G.R., Multiple Ion Channel Block of Chloroform is Involved in its Arrhythmogenic Effect, J HK Coll Cardiol. 2008, 16(2): 68.


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