DEPT OF PHARMACOLOGY
| Researcher : Bai B |
| List of Research Outputs |
| Bai B. and Wang Y., The use of lorcaserin in the management of obesity: a critical appraisal. , Drug Design, Development and Therapy.. 2010, 5: 1-7. |
| Researcher : Chan CKY |
| List of Research Outputs |
| Chan C.K.Y., Mak J.C.W. and Vanhoutte P.M.G.R., Secretoneurin Induces Endothelium-dependent Relaxation of the Porcine Coronary Artery, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 222. |
| Researcher : Chan KYC |
| List of Research Outputs |
| Chan K.Y.C., Mak J.C.W., Man R.Y.K. and Vanhoutte P.M.G.R., Endothelium-derived NO is Required for Contraction to Hypoxia in Porcine Coronary Arteries, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 176. |
| Chan K.Y.C., Mak J.C.W., Man R.Y.K. and Vanhoutte P.M.G.R., Hypoxic endothelium-dependent contractions of the porcine coronary artery requires activation of both nitric oxide synthase and soluble guanylyl cyclase, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 17. |
| Chan K.Y.C. and Vanhoutte P.M.G.R., Secretoneurin facilitates endothelium-dependent relaxations in porcine coronary arteries, Am J Physiol Heart Circ Physiol. 2011, 300: H1159-H1165. |
| Researcher : Chan MLY |
| List of Research Outputs |
| Leung S.W.S., Chan M.L.Y., Man G.S.K. and Man R.Y.K., Inhibition of cyclooxygenase activity improves endothelium-dependent relaxation in mesenteric arteries ovariectomized rats following chronic inhibition of nitric oxide synthase, 16th World Congress of Pharmacology and Clinical Pharmacology, July 17-23, 2010 Copenhagen, Denmark. 2010. |
| Researcher : Che CM |
| Project Title: | Blue light photoluminescent materials |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Hung Hing Ying Physical Sciences Research Fund |
| Start Date: | 02/1999 |
| Project Title: | Institute of molecular technology for drug discovery and synthesis |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Areas of Excellence Scheme |
| Start Date: | 11/2001 |
| Project Title: | Research and development of luminescent biosensors for drug screening and environmental monitoring |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 11/2002 |
| Project Title: | Functional nanomaterials research |
| Investigator(s): | Che CM, Chan MCW |
| Department: | Chemistry |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Project Title: | Molecular Design and Application Studies of Photoluminescent Platinum(II) Complexes |
| Investigator(s): | Che CM, Lu W, Tong SM, Vellaisamy ALR |
| Department: | Chemistry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2007 |
| Completion Date: | 08/2010 |
| Project Title: | Institute of molecular technology for drug discovery and synthesis - sustained funding |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Areas of Excellence Scheme |
| Start Date: | 10/2007 |
| Project Title: | Functional self-assembled metal coordination polymers and supramolecular systems containing extended π-conjugated organic ligands |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Travel Grants for NSFC/RGC JRS |
| Start Date: | 12/2007 |
| Project Title: | Drug |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 06/2008 |
| Completion Date: | 05/2011 |
| Project Title: | Research & Development of New Materials for Printable Electronics |
| Investigator(s): | Che CM, Vellaisamy ALR, Kwok CC, Kui CF, Ma CW |
| Department: | Chemistry |
| Source(s) of Funding: | Platform Research Projects |
| Start Date: | 07/2008 |
| Project Title: | High-Performance Tandem Mass Spectrometry Facility for Functional Proteomics and Metabolomics |
| Investigator(s): | Che CM, Cheah KSE, Ma CY, Lee HC, Chan D, Tanner JA, Xu A, Sun H, Ip NY, Wong WT, Poon RTP, Wang Y, Ng KM, Chu IK, Siu AFM, Chen SF, Chye ML, Lo CSC |
| Department: | Chemistry |
| Source(s) of Funding: | UGC One-off Special Equipment Grant Scheme |
| Start Date: | 12/2008 |
| Project Title: | Self-assembled metal coordination polymers and supramolecular systems containing π-conjugated organic ligands |
| Investigator(s): | Che CM, Lai SW |
| Department: | Chemistry |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2009 |
| Project Title: | Metal-Catalyzed Atom and Group Transfer Reactions for Selective Functionalization of Carbon-Hydrogen Bonds |
| Investigator(s): | Che CM, Ho CM, Tong SM |
| Department: | Chemistry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | Reactive Metal-Ligand Multiple Bonded Complexes. From Biomimetic Reactions to Highly Efficient Chemical Synthesis |
| Investigator(s): | Che CM, Phillips DL, Chiu P, Huang JS |
| Department: | Chemistry |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 03/2009 |
| Project Title: | Green Chemistry: Application of Nanotechnology in the Development of Highly Efficient and Environmental Friendly Chemical Synthesis |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 04/2009 |
| Project Title: | Green Chemistry: Application of Nanotechnology in the Development of Highly Efficient and Environmental Friendly Chemical Synthesis |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 04/2009 |
| Project Title: | Research & Development of New Materials for Printable Electronics |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme (NAMI) |
| Start Date: | 07/2009 |
| Project Title: | New Materials for Organic/polymer Base Photovoltaic Cells |
| Investigator(s): | Che CM, Kwok CC, Kui CF |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 3) |
| Start Date: | 10/2009 |
| Project Title: | Research & Development of New Materials for Printable Electronics |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme (NAMI) |
| Start Date: | 11/2009 |
| Project Title: | Oxidation Chemistry of Silver Nanoparticles |
| Investigator(s): | Che CM, Lok CN, Ho CM |
| Department: | Chemistry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Phosphorescent Metal Complexes with d8 and d10 Electronic Configurations. Photochemistry, and Self-Assembled Nanostructure |
| Investigator(s): | Che CM, Lu W, Tong SM |
| Department: | Chemistry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | New Materials for Organic/polymer Base Photovoltaic Cells |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 01/2010 |
| Project Title: | Discovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads |
| Investigator(s): | Che CM, Sun RWY, Vanhoutte PMGR, Lin MC, Poon RTP, Wang Y, Siu AFM, Ma DL, Leung CH, Lau CK |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 2) |
| Start Date: | 03/2010 |
| Project Title: | Discovery and Pre-Clinical Evaluation of Promising Metal-Based Anti-Cancer Drug Leads |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 04/2010 |
| Project Title: | New Materials for Organic/polymer Base Photovoltaic Cells |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 06/2010 |
| Project Title: | Transition Metal-Catalysed Oxygenation Reactions. Biomimetic and Photochemical Approaches |
| Investigator(s): | Che CM, Wong ELM, Guo Z, Ng KM |
| Department: | Chemistry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2011 |
| Project Title: | Research and development of phosphorescent organic light emitting diode (OLED) materials and prototype devices for lighting applications |
| Investigator(s): | Che CM, Kwok CC, Kui CF, Low KH, Cheng G, Ma CW |
| Department: | Chemistry |
| Source(s) of Funding: | Guangdong-Hong Kong Technology Cooperation Funding Scheme |
| Start Date: | 03/2011 |
| Project Title: | High-Valent Iron-Imido and Iron-Oxo Complexes: Synthesis, Characterization and Reactivity |
| Investigator(s): | Che CM |
| Department: | Chemistry |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2011 |
| List of Research Outputs |
| Lum C.T., Huo L., Sun R.W.Y., Li M., Kung H.F., Che C.M. and Lin M.C., Gold(III) porphyrin 1a prolongs the survival of melanoma-bearing mice and inhibits angiogenesis, Acta Oncologica. 2011, 2011: 719-726. |
| Researcher : Cho CH |
| Project Title: | Advances in GI Pharmacology - From Acid Secretion to Mucosal Protection Symposium Non-ulcerogenic Dose of Dexamethasone Delays Gastric Ulcer Healing in Rats |
| Investigator(s): | Cho CH |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 11/2004 |
| Project Title: | Adrenaline and its receptor activation on colon cancer growth |
| Investigator(s): | Cho CH |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2006 |
| List of Research Outputs |
| Wong H.P.S., Ho J.W.C., Koo M.W.L., Yu L., Wu K.K., Lam K.Y., Tai K.K., Ko J.K., Shin V.Y., Chu K.M. and Cho C.H., Effects of adrenaline in human colon adenocarcinoma HT-29 cells, Life Sciences. 2011, 88: 1108-1112. |
| Researcher : Chow HM |
| List of Research Outputs |
| Fan P., Chow H.M., Xu A. and Wang Y., Stromal-tumor Interactions Mediated by Lipocalin-2, a Pro-inflammatory Adipokine, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 159. |
| Researcher : Fan P |
| List of Research Outputs |
| Fan P., Chow H.M., Xu A. and Wang Y., Stromal-tumor Interactions Mediated by Lipocalin-2, a Pro-inflammatory Adipokine, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 159. |
| Researcher : Ho YW |
| List of Research Outputs |
| Li R.W.S., Yang C., Sit S.M., Lin Y.T., Ho Y.W. and Leung G.P.H., Physiological and pharmacological roles of vascular nucleoside transporters, Fourth Scientific Meeting of the Asian Society for Vascular Biology, 20 November 2010. 12. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine protects endothelial cells from oxidative stress, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Sceintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 77. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine shows protective effct on endothelial cells in oxidative stress, Experimental Biology, Washington DC USA, April 9-13, 2011. 183. |
| Sit S.M., Ho Y.W., Li R.W.S., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Potential Beneficial Effect of Ergothioneine in Protecting Endothelial Dysfunction, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 583. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective Effect of Ergothioneine on Endothelial Cells against Oxidative Stress, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2011. 2010, 93. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y...W..., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective effect of ergothioneine on ednothelial cell against oxidative stress, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20-21 November 2010. 34. |
| Researcher : Kong BWC |
| List of Research Outputs |
| Kong B.W.C., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Female Apolipoprotein E-deficient Mice are Protected Against the Development of Endothelial Dysfunction with Ageing, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 148. |
| Researcher : Kong WCB |
| List of Research Outputs |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., 17bEstradiol acutely improves endothelial dysfunction associated with ageing, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 28. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Endothelium Dependent Relaxations Are Improved by Acute Treatment of 17bestradiol in Atherosclerotic Mice with Ageing , 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 180. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Female apolipoproteinE-deficient mice are protected against the development of endothelial dysfunction with ageing, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Researcher : Koo MWL |
| Project Title: | A cell-base co-culture system for the evaluation of green tea catechin, epigallocatechin gallate, in insulin resistance |
| Investigator(s): | Koo MWL |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| List of Research Outputs |
| Koo M.W.L., Memory enhancing effect of tea, Sixth International Symposium on Healthy Aging "A New Golden Age". 2010. |
| Wong H.P.S., Ho J.W.C., Koo M.W.L., Yu L., Wu K.K., Lam K.Y., Tai K.K., Ko J.K., Shin V.Y., Chu K.M. and Cho C.H., Effects of adrenaline in human colon adenocarcinoma HT-29 cells, Life Sciences. 2011, 88: 1108-1112. |
| Researcher : Lam JKW |
| Project Title: | Investigation of intracellular trafficking of peptide-based nucleic acids delivery system using live cell confocal imaging |
| Investigator(s): | Lam JKW |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2010 |
| Completion Date: | 12/2010 |
| Project Title: | Investigation of siRNA delivery to macrophages: potential novel therapy for the treatment of tuberculosis |
| Investigator(s): | Lam JKW, Yam WC |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2011 |
| List of Research Outputs |
| Lam J.K.W., Liang W. and Chan H.K., Pulmonary delivery of therapeutic siRNA, Advanced Drug Delivery Reviews. 2011. |
| Lam J.K.W., Armes S.P. and Stolnik S., The involvement of microtubules and actin filaments in the intracellular transport of non-viral gene delivery vector., Journal of Drug Targeting. 2011, 19: 55. |
| Lan Y., Ye Y., Kozlowska J., Lam J.K.W., Drake A.F. and Mason A.J., Structural contributions to the intracellular targeting strategy of antimicrobial peptides, Biochimica et biophysica acta (BBA) - Biomembranes. 2010, 1709: 1934-1943. |
| Wang Y., Lam J.K.W., Zhang B., Tomlins P.E., Li X., Alpar O., Wertheim D.F., Jones A.S. and Coombes A.G.A., Biomechanical Characterization of a Micro/Macroporous Polycaprolactone Tissue Integrating Vascular Graft, Cardiovascular Engineering and Technology. 2010, 1: 202-205. |
| Researcher : Lam MPS |
| List of Research Outputs |
| Lam M.P.S., Pharmacist's approach to complementary and alternative medicine in cancer treatment - how to make informed decision, Hong Kong Pharmacy Conference 2011. 2011. |
| Researcher : Lan Y |
| List of Research Outputs |
| Lan Y., Ye Y., Kozlowska J., Lam J.K.W., Drake A.F. and Mason A.J., Structural contributions to the intracellular targeting strategy of antimicrobial peptides, Biochimica et biophysica acta (BBA) - Biomembranes. 2010, 1709: 1934-1943. |
| Researcher : Lau YT |
| List of Research Outputs |
| Lau Y.T., Leung S.W.S. and Man R.Y.K., Modulation of vascular reactivity by kaempferol in porcine coronary arteries, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Researcher : Law KM |
| List of Research Outputs |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Law K.M., Zhou M. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/ Reperfusion Injury, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 188. |
| Researcher : Law KM |
| List of Research Outputs |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Law K.M., Zhou M. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/ Reperfusion Injury, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 188. |
| Researcher : Lee MYK |
| List of Research Outputs |
| Lee M.Y.K., Li A.H., Xiao Y., Zhou Z...G., Xu A. and Vanhoutte P.M.G.R., Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells, British Journal of Pharmacology. 2011, (2011) 162: 1564-1576. |
| Lee M.Y.K. and Vanhoutte P.M.G.R., Inflammation and endothelial dysfunction with aging, Endothelial Dysfunction and Inflammation. 2010, 189-200. |
| Liu J., Zu Y., Lam K.S.L., Lee M.Y.K., Vanhoutte P.M.G.R., Xu A. and Wang Y., SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aorteic Endothelial Cells, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 184. |
| Vanhoutte P.M.G.R., Lee M.Y.K., Wang Y. and Tse H.F., Genomic Changes Caused by Chronic Exposure to High Cholesterol or Fish Oil in Native and Regenerated Porcine Coronary Endothelial Cells, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 633-634. |
| Researcher : Leung GPH |
| Project Title: | Cloning and characterization of novel equilibrative nucleoside transporter type 4 (ENT4) |
| Investigator(s): | Leung GPH |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2005 |
| Project Title: | Characterization and physiological role of 5HT transport systems in vascular cells |
| Investigator(s): | Leung GPH, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2009 |
| Completion Date: | 09/2010 |
| Project Title: | Effects of inflammation on concentrative nucleoside transporter-2 in human brain microvascular endothelial cells |
| Investigator(s): | Leung GPH |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2009 |
| Completion Date: | 04/2011 |
| Project Title: | Abacavir, an antiviral nucleoside analogue, increases the risk of cardiovascular events by causing endothelial dysfunction |
| Investigator(s): | Leung GPH, Vanhoutte PMGR, Xia Z |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2009 |
| Project Title: | Protective effect of ergothioneine on endothelial cell function against oxidative stress |
| Investigator(s): | Leung GPH, Xia Z |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2010 |
| Project Title: | Re-uptake system of epoxyeicosatrienoic acids in vascular cells |
| Investigator(s): | Leung GPH |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2011 |
| List of Research Outputs |
| Au A.L.S., Poon C.C.W., Zhang Q., Leung G.P.H., Kong S.K., Ho H.P. and Kwan Y.W., Restoration of Blunted Insulin Release and [Ca2+], Changed by Simvastatin of Isolated Pancreatic Islets of Langerhans of Obese/Diabetic (db/db+) Mice, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December, 2010. 18:2: 67. |
| Chan E., Liu X.X., Guo D.J., Kwan Y.W., Leung G.P.H., Lee S.M. and Chan S.W., Extract of Scutellaria baicalensis Georgi Root Exerts Protection Against Myocardial Ischemia-Reperfusion Injury in Rats, American Journal of Chinese Medicine. 2011, 39: 693-704. |
| Deng Y.H., Alex D., Huang H.Q., Wang N., Yu N., Wang Y.T., Leung G.P.H. and Lee S.M., Inhibition of TNF-α-mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4'-trimethoxystilbene, Phytotherapy Research . 2011, 25: 451-457. |
| Eguti D.M.N., Thieme K., Leung G.P.H., Mello-Aires M. and Oliveira-Souza M., Regulation of Na+/H+ exchanger isoform 1 (NHE1) by calmodulin-binding sites: role of angiotensin II, Cellular Physiology and Biochemistry . 2010, 26: 541-552. |
| Leung G.P.H., Physiological and Pharmacological roles of vascular nucleoside transporters, 4th scientific meeting of the Asian Society for Vascular Biology, Hong Kong . 2010. |
| Li R.W.S., Kwan Y.W. and Leung G.P.H., Does abacavir treatment increase the cardiovascular risks?, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November 2010. 38. |
| Li R.W.S., Yang C., Sit S.M., Lin Y.T., Ho Y.W. and Leung G.P.H., Physiological and pharmacological roles of vascular nucleoside transporters, Fourth Scientific Meeting of the Asian Society for Vascular Biology, 20 November 2010. 12. |
| Li R.W.S., Kwan Y.W. and Leung G.P.H., Possible mechanisms underlying abacavir-related cardiovascular complications, Cardiovascular Research, Journal of the European Society of Cardiology, Final Programme and Abstract Book of: Frontiers in Cardiovascular Biology Berlin Germany, 16-19 July, 2010. 87 Supplement 1: S56. |
| Li W.S.R., Kwan Y.W. and Leung G.P.H., Effects of Abacavir Treatment on Vascular System, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 182. |
| Lin A.H.Y., Leung G.P.H., Leung S.W.S. and Man R.Y.K., The Ligand Binding Properties of Human Membrane Estrogen Receptors, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 415. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S. and Man R.Y.K., ER46 is the predominant membrane estrogen receptor at physiological estrogen level in human, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 17. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Genistein enhances relaxation of the spontaneously hypertensive rat aorta by transactivation of epidermal growth factor receptor following binding to membrane estrogen receptors-a and activation of a G protein-coupled, endothelial nitric oxide synthase-dependent pathway, Pharmacological Research. 2010, 63: 181-189. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S. and Man R.Y.K., The ligand binding properties of human membrane estrogen receptors, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Poon C.C.W., Seto S.W., Au A.L.S., Zhang Q., Li R.W.S., Lee W.Y.W., Chan S.W., Leung G.P.H., Kong S.K., Yeung J.H.K., Ngai S.M., Ho A.H.P., Lee S.M.Y. and Kwan Y.W., Mitochondrial monoamine oxidase A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery, British Journal of Pharmacology. 2010, 161: 1086-1098. |
| Poon C.C.W., Au A.L.S., Zhang Q., Kong S.K., Ho H.P., Leung G.P.H. and Kwan Y.W., N-Acetyl.-L-Cysteine Reduces High Glucose-Induced Mitochondrial ROS Generation and Cortical F-Actin Cytoskeleton Levels in Pancreatic Islets b-Cells of Obese/Diabetic Mice, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 77. |
| Seto S.W., Lam T.Y., Or P.M., Lee W.Y., Au A.L.S., Poon C.C.W., Li R.W.S., Chan S.W., Yeung J.H.K., Leung G.P.H., Lee S.M., Ngai S.M. and Kwan Y.W., Folic acid consumption reduces resistin level and restores blunted acetylcholine-induced aortic relaxation in obese/diabetic mice, Journal of Nutritional Biochemistry . 2010, 21: 872-880. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine protects endothelial cells from oxidative stress, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Sceintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 77. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine shows protective effct on endothelial cells in oxidative stress, Experimental Biology, Washington DC USA, April 9-13, 2011. 183. |
| Sit S.M., Ho Y.W., Li R.W.S., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Potential Beneficial Effect of Ergothioneine in Protecting Endothelial Dysfunction, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 583. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective Effect of Ergothioneine on Endothelial Cells against Oxidative Stress, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2011. 2010, 93. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y...W..., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective effect of ergothioneine on ednothelial cell against oxidative stress, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20-21 November 2010. 34. |
| Tang J.Y., Li S., Li Z.H., Zhang Z.J., Hu G., Cheang L.C., Alex D., Hoi M.P., Kwan Y.W., Chan S.W., Leung G.P.H. and Lee S.M., Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC, PLoS One. 2010, 5: e11822. |
| Wu J.H., Li Q., Wu M.Y., Quo D.J., Chen H.L., Chen S.L., Seto S.W., Au A.L., Poon C.L., Leung G.P.H., Lee S.M., Kwan Y.W. and Chan S.W., Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways, Journal of Nutritional Biochemistry . 2010, 21: 613-620. |
| Yang C., Kwan Y.W., Au A.L.S., Poon C.C.W., Zhang Q., Chan S.W., Lee S.M. and Leung G.P.H., 14,15-Epoxyeicosatrienoic acid induces vasorelaxation through the prostaglandin EP(2) receptors in rat mesenteric artery, Prostaglandins and Other Lipid Mediator . 2010, 93: 44-51. |
| Yang C., Kwan Y.W., Chan S.W., Lee S.M. and Leung G.P.H., Potentiation of EDHF-mediated relaxation by chloride channel blockers, Acta Pharmacologica Sinica . 2010, 31: 1303-1311. |
| Zhang Q., Au A.L.S., Poon C.C.W., Leung G.P.H., Kong S.K., Ho H.P. and Kwan Y.W., Monoamine oxidase-A-mediated generation of reactive oxygen species by 5-hydroxytryptamine in HUVECs, Journal of the Hong Kong College of Cardiology . 2010, 18(2): 80. |
| Zhang Q., Wong M.F., Kwok F.Y., Au A.L.S., Poon C.C.W., Leung G.P.H., Kong S.K., Ho H.P., Cho C.H. and Kwan Y.W., Role of AMPK and HMG Coa reductase in simvastatin-mediated insulin release from porcine isolated pancreatic islets of langerhans, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 80. |
| Researcher : Leung SWS |
| Project Title: | Regulation of endothelial-derived hyperpolarizing factor-mediated responses in physiological and pathological conditions |
| Investigator(s): | Leung SWS, Leung GPH, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2007 |
| Completion Date: | 09/2010 |
| Project Title: | Acceleration of the senescence of the endothelium by high blood pressure |
| Investigator(s): | Leung SWS, Lee MYK, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2008 |
| Project Title: | Effect of genistein on the activity of platelets of ovariectomized rats |
| Investigator(s): | Leung SWS, Man RYK |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2009 |
| Completion Date: | 04/2011 |
| Project Title: | Nitric oxide signaling pathway involved in the inhibition of the release of endothelium-derived contracting factor in hypertension |
| Investigator(s): | Leung SWS |
| Department: | Pharmacology |
| Source(s) of Funding: | Travel Grants for NSFC/RGC JRS |
| Start Date: | 12/2009 |
| Project Title: | The influence of gender on endothelial senescence and dysfunction in Apolipoprotein E-deficient mice: role of sirtuin and telomerase |
| Investigator(s): | Leung SWS, Man RYK |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2009 |
| Completion Date: | 05/2011 |
| Project Title: | 16th World Congress on Basic and Clinical Pharmacology (WorldPharma 2010) Inhibition of cyclooxygenase activity improves endothelium-dependent relaxation in mesenteric arteries of ovariectomized rats following chronic inhibition of nitric oxide synthase |
| Investigator(s): | Leung SWS |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 07/2010 |
| Completion Date: | 07/2010 |
| Project Title: | Assessment of vascular reactivity in protease inhibitor treatment using a rat model |
| Investigator(s): | Leung SWS, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| List of Research Outputs |
| Kong B.W.C., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Female Apolipoprotein E-deficient Mice are Protected Against the Development of Endothelial Dysfunction with Ageing, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 148. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., 17bEstradiol acutely improves endothelial dysfunction associated with ageing, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 28. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Endothelium Dependent Relaxations Are Improved by Acute Treatment of 17bestradiol in Atherosclerotic Mice with Ageing , 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 180. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Female apolipoproteinE-deficient mice are protected against the development of endothelial dysfunction with ageing, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Lau Y.T., Leung S.W.S. and Man R.Y.K., Modulation of vascular reactivity by kaempferol in porcine coronary arteries, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Leung S.W.S., Chan M.L.Y., Man G.S.K. and Man R.Y.K., Inhibition of cyclooxygenase activity improves endothelium-dependent relaxation in mesenteric arteries ovariectomized rats following chronic inhibition of nitric oxide synthase, 16th World Congress of Pharmacology and Clinical Pharmacology, July 17-23, 2010 Copenhagen, Denmark. 2010. |
| Leung S.W.S., Man G.S.K. and Man R.Y.K., Long-term administration of rutin, a dietary flavonoid, increases the hypotensive actions of acetylcholine in spontaneously hypertensive rats., Acta Physiologica, Official Journal of the Federation of European Physiological Societies, Abstracts for the 12th Symposium on Vascular Neuroeffector Mechanisms. July 24-26, 2010. Odense, Denmark. . 2010, 199: 33. |
| Lin A.H.Y., Leung G.P.H., Leung S.W.S. and Man R.Y.K., The Ligand Binding Properties of Human Membrane Estrogen Receptors, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 415. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S. and Man R.Y.K., ER46 is the predominant membrane estrogen receptor at physiological estrogen level in human, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 17. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Genistein enhances relaxation of the spontaneously hypertensive rat aorta by transactivation of epidermal growth factor receptor following binding to membrane estrogen receptors-a and activation of a G protein-coupled, endothelial nitric oxide synthase-dependent pathway, Pharmacological Research. 2010, 63: 181-189. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S. and Man R.Y.K., The ligand binding properties of human membrane estrogen receptors, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Man R.Y.K., Man G.S.K. and Leung S.W.S., Long-term administration of rutin, a dietary flavonoid, increases the hypotensive actions of acetylcholine in spontaneously hypertensive rats, 12th Symposium of Vascular Neuroeffector Mechanisms, Odense, Denmark. 2010. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Beneficial Vascular Effect of a Non-selective PPAR Activator in Aorta of Spontaneously Hypertensive Rats, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 186. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Involvement of AMPK in the beneficial vascular effect of a non-selective PPAR activator in aorta of spontaneousley hypertensive rats, Experimental Biology, Washington, DC, USA, April 9-13, 2011. 259. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Vascular effect of a non-selective PPAR activator in aorta of spontaneously hypertensive rats, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November, 2010. 32. |
| Yeung Y.T., Leung S.W.S. and Man R.Y.K., Study of vascular effects of protease inhibitors and non-nucleside reverse transcriptase inhibitors on mesenteric arteries, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November 2010. 38. |
| Yeung Y.T., Lee S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Vascular Effects of Protease Inhibitors and Non-nucleoside Reverse Transcriptase Inhibitors, the Major Components of Highly Active Antiretroviral Therapy [HAART], 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 97. |
| Yeung Y.T., Lee S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Vascular effects of protease inhibitors and non-nucleoside reverse transcriptase inhibitors, the major components of highly active antiretroviral therapy [HAART], 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Zhang Y., Leung S.W.S. and Man R.Y.K., Gender-Specific Relaxation of Flavonoids in Rat Mesenteric Arteries, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 81. |
| Zhang Y., Leung S.W.S. and Man R.Y.K., Gender-specific relaxation effects of luteoin in rat mesenteric arteries, Experimental Biology, Washington, DC USA, April 9-13, 2011. 184. |
| Zhao Y., Leung S.W.S. and Vanhoutte P.M.G.R., Endothelial Nos-Independent Release of Nitric-Oxide in the Aorta of the Spontaneously Hypertensive Rat, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 72. |
| Zhao Y., Leung S.W.S. and Vanhoutte P.M.G.R., Previous exposure to nitric oxide inhibits subsequent contractions evoked by prostaglandin E2, prostaglandin D2 and prostaglandin F2a, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November, 2010. 33. |
| Zheng X., Ying L., Liu J., Dou D., He Q., Leung S.W.S., Man R.Y.K., Vanhoutte P.M.G.R. and Gao Y., Role of sulfhydryl-dependent dimerization of soluble guanylyl cyclase in relaxation of porcine coronary artery to nitric oxide, Cardiovasc Research . 2011, 90: 565-572. |
| Researcher : Li AH |
| List of Research Outputs |
| Lee M.Y.K., Li A.H., Xiao Y., Zhou Z...G., Xu A. and Vanhoutte P.M.G.R., Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells, British Journal of Pharmacology. 2011, (2011) 162: 1564-1576. |
| Researcher : Li RWS |
| List of Research Outputs |
| Li R.W.S., Kwan Y.W. and Leung G.P.H., Does abacavir treatment increase the cardiovascular risks?, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November 2010. 38. |
| Li R.W.S., Yang C., Sit S.M., Lin Y.T., Ho Y.W. and Leung G.P.H., Physiological and pharmacological roles of vascular nucleoside transporters, Fourth Scientific Meeting of the Asian Society for Vascular Biology, 20 November 2010. 12. |
| Li R.W.S., Kwan Y.W. and Leung G.P.H., Possible mechanisms underlying abacavir-related cardiovascular complications, Cardiovascular Research, Journal of the European Society of Cardiology, Final Programme and Abstract Book of: Frontiers in Cardiovascular Biology Berlin Germany, 16-19 July, 2010. 87 Supplement 1: S56. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine protects endothelial cells from oxidative stress, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Sceintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 77. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine shows protective effct on endothelial cells in oxidative stress, Experimental Biology, Washington DC USA, April 9-13, 2011. 183. |
| Sit S.M., Ho Y.W., Li R.W.S., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Potential Beneficial Effect of Ergothioneine in Protecting Endothelial Dysfunction, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 583. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective Effect of Ergothioneine on Endothelial Cells against Oxidative Stress, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2011. 2010, 93. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y...W..., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective effect of ergothioneine on ednothelial cell against oxidative stress, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20-21 November 2010. 34. |
| Researcher : Li WSR |
| List of Research Outputs |
| Li W.S.R., Kwan Y.W. and Leung G.P.H., Effects of Abacavir Treatment on Vascular System, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 182. |
| Researcher : Li Z |
| List of Research Outputs |
| Li Z., Wang Y... and Vanhoutte P...M...G..., Epigallocatechin gallate elicits contractions of the isolated aorta of the aged spontaneously hypertensive rat, Basic & Clinical Pharmacology & Toxicology. 2011, 2011: 1742-7843. |
| Li Z. and Vanhoutte P.M.G.R., Up-Regulation of heme oxygenase-1 Improves endothelial functions by impairing endothelium-dependent contractions and enhancing endothelium-dependent hyperpolarizations , Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science & Mediicine, 18 December2010. 66, 18:2. |
| Li Z. and Vanhoutte P.M.G.R., Up-regulation of Heme Oxygenase-1 Impairs Endothelium-dependent Contractions, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 87. |
| Li Z. and Vanhoutte P.M.G.R., Up-regulation of heme oxygenase-1 improves endothelial function in arteries of the spontaneously hypertensive rat, Fourth Scientific Meeting of the Asian Society Vascular Biology, Hong Kong, 20 November 2010. 29. |
| Researcher : Liang C |
| List of Research Outputs |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Loss of function in toll-like receptor 4 receptors nitric oxide-mediated relaxations in Leprdb/dbmice, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 63. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Loss-of-function in Toll-like receptor 4 (TLR4) alleviates metabolic syndrome and endothelial dysfunction in genetically obese mice., Acta Physiologica, Official Journal of the Federation of European Physiological Societies, Abstracts for the 12th Symposium on Vascular Neuroeffector Mechanisms. July 24-26, 2010. Odense, Denmark. . 2010, 199: 15. |
| Liang C., Man R.Y.K., Xu A. and Vanhoutte P.M.G.R., Toll-Like Receptor 4 Mutation Alleviates Endothelial Dysfunction in Genetically Obese Mice, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 183. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Toll-like Receptor 4 Mediates the Vasoconstrictor Response Initiated by Adipose Tissue in Mice Arteries, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 413. |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Researcher : Liang C |
| List of Research Outputs |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Loss of function in toll-like receptor 4 receptors nitric oxide-mediated relaxations in Leprdb/dbmice, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 63. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Loss-of-function in Toll-like receptor 4 (TLR4) alleviates metabolic syndrome and endothelial dysfunction in genetically obese mice., Acta Physiologica, Official Journal of the Federation of European Physiological Societies, Abstracts for the 12th Symposium on Vascular Neuroeffector Mechanisms. July 24-26, 2010. Odense, Denmark. . 2010, 199: 15. |
| Liang C., Man R.Y.K., Xu A. and Vanhoutte P.M.G.R., Toll-Like Receptor 4 Mutation Alleviates Endothelial Dysfunction in Genetically Obese Mice, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 183. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Toll-like Receptor 4 Mediates the Vasoconstrictor Response Initiated by Adipose Tissue in Mice Arteries, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 413. |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Researcher : Liang W |
| List of Research Outputs |
| Lam J.K.W., Liang W. and Chan H.K., Pulmonary delivery of therapeutic siRNA, Advanced Drug Delivery Reviews. 2011. |
| Researcher : Liang Y |
| List of Research Outputs |
| Wang Y., Liang Y. and Vanhoutte P.M.G.R., SIRT1 and AMPK in regulating mammalian senescence: A critical review and a working model. , FEBS Letters. 2010. |
| Researcher : Lin AHY |
| List of Research Outputs |
| Lin A.H.Y., Leung G.P.H., Leung S.W.S. and Man R.Y.K., The Ligand Binding Properties of Human Membrane Estrogen Receptors, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 415. |
| Researcher : Lin HYA |
| List of Research Outputs |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S. and Man R.Y.K., ER46 is the predominant membrane estrogen receptor at physiological estrogen level in human, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 17. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Genistein enhances relaxation of the spontaneously hypertensive rat aorta by transactivation of epidermal growth factor receptor following binding to membrane estrogen receptors-a and activation of a G protein-coupled, endothelial nitric oxide synthase-dependent pathway, Pharmacological Research. 2010, 63: 181-189. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S. and Man R.Y.K., The ligand binding properties of human membrane estrogen receptors, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Researcher : Lin YT |
| List of Research Outputs |
| Li R.W.S., Yang C., Sit S.M., Lin Y.T., Ho Y.W. and Leung G.P.H., Physiological and pharmacological roles of vascular nucleoside transporters, Fourth Scientific Meeting of the Asian Society for Vascular Biology, 20 November 2010. 12. |
| Researcher : Liu J |
| List of Research Outputs |
| Liu J., Xu A. and Wang Y., Adiponectin deficiency accelerates breast cancer development and promotes cholesterol accumulation in mammary tumors of MMTV-Polyomavirus Middle T Antigen mice, 33nd Annual CTRC-AACR San Antonio Breast Cancer Symposium. San Antonio, Texas, USA, 2010. |
| Liu J., Xu A., Lam K.S.L. and Wang Y., Deficiency of Adiponectin, a Hormone Selectively Secreted from Fat Cells, Accelerated Breast Cancer Development and Promoted Cholesterol Accumulation in Mammary Tumors of MMTV-Polyomavirus Meiddle T Antigen Mice, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 230. |
| Liu J., Zu Y., Lam K.S.L., Lee M.Y.K., Vanhoutte P.M.G.R., Xu A. and Wang Y., SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aorteic Endothelial Cells, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 184. |
| Researcher : Liu TC |
| List of Research Outputs |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Researcher : Mak JCW |
| Project Title: | Role of transforming growth factor-beta1 variants in susceptibility to tuberculosis in Hong Kong Chinese population |
| Investigator(s): | Mak JCW, Chan MMW |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2005 |
| Project Title: | Effects of intermittent hypoxia and/or cigarette smoking on endothelial injury in vivo - relevant to obstructive sleep apnea |
| Investigator(s): | Mak JCW, Ip MSM |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2008 |
| Completion Date: | 03/2011 |
| Project Title: | Pre- and post-operation sputum and serum tumor markers in non-small cell lung cancer patients |
| Investigator(s): | Mak JCW, Lam B |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2009 |
| Completion Date: | 03/2011 |
| Project Title: | Involvement of serotoninergic system in cigarette smoke-induced inflammatory responses in human airway epithelial cells |
| Investigator(s): | Mak JCW |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2010 |
| Completion Date: | 04/2011 |
| Project Title: | Effects of cigarette smoke on regulation of the expression of adiponectin and its receptors in airway cells |
| Investigator(s): | Mak JCW, Ip MSM |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2010 |
| Project Title: | Signaling pathways on intermittent hypoxia-induced oxidative stress in human EAhy 926 endothelial cell line |
| Investigator(s): | Mak JCW |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Chan C.K.Y., Mak J.C.W. and Vanhoutte P.M.G.R., Secretoneurin Induces Endothelium-dependent Relaxation of the Porcine Coronary Artery, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 222. |
| Chan K.Y.C., Mak J.C.W., Man R.Y.K. and Vanhoutte P.M.G.R., Endothelium-derived NO is Required for Contraction to Hypoxia in Porcine Coronary Arteries, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 176. |
| Chan K.Y.C., Mak J.C.W., Man R.Y.K. and Vanhoutte P.M.G.R., Hypoxic endothelium-dependent contractions of the porcine coronary artery requires activation of both nitric oxide synthase and soluble guanylyl cyclase, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 17. |
| Researcher : Man GSK |
| List of Research Outputs |
| Leung S.W.S., Chan M.L.Y., Man G.S.K. and Man R.Y.K., Inhibition of cyclooxygenase activity improves endothelium-dependent relaxation in mesenteric arteries ovariectomized rats following chronic inhibition of nitric oxide synthase, 16th World Congress of Pharmacology and Clinical Pharmacology, July 17-23, 2010 Copenhagen, Denmark. 2010. |
| Leung S.W.S., Man G.S.K. and Man R.Y.K., Long-term administration of rutin, a dietary flavonoid, increases the hypotensive actions of acetylcholine in spontaneously hypertensive rats., Acta Physiologica, Official Journal of the Federation of European Physiological Societies, Abstracts for the 12th Symposium on Vascular Neuroeffector Mechanisms. July 24-26, 2010. Odense, Denmark. . 2010, 199: 33. |
| Man R.Y.K., Man G.S.K. and Leung S.W.S., Long-term administration of rutin, a dietary flavonoid, increases the hypotensive actions of acetylcholine in spontaneously hypertensive rats, 12th Symposium of Vascular Neuroeffector Mechanisms, Odense, Denmark. 2010. |
| Researcher : Man RYK |
| Project Title: | Mechanism for the modulation of vascular function by flavonoids |
| Investigator(s): | Man RYK, Leung GPH, Leung SWS |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2007 |
| Completion Date: | 08/2010 |
| Project Title: | Outstanding Research Student Supervisor Award 2007-2008 |
| Investigator(s): | Man RYK |
| Department: | Pharmacology |
| Source(s) of Funding: | Outstanding Research Student Supervisor Award |
| Start Date: | 10/2008 |
| Project Title: | Beneficial vascular effect of estrogen is medicated by the activation of GPR30 in endothelial and vascular smooth muscle cells |
| Investigator(s): | Man RYK, Leung SWS, Leung GPH |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2009 |
| Completion Date: | 05/2011 |
| Project Title: | 12th Symposium of Vascular Neuroeffector Mechanisms Long-term administration of rutin, a dietary flavonoid, increases the hypotensive actions of acetylcholine in spontaneously hypertensive rats |
| Investigator(s): | Man RYK |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 07/2010 |
| Completion Date: | 07/2010 |
| Project Title: | Protective effects of vitamin D on endothelial dysfunction in hypertension |
| Investigator(s): | Man RYK, Leung SWS, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | Effects of different isoflavones on the activity of phosphodiesterase (PDE) in porcine coronary artery |
| Investigator(s): | Man RYK, Leung SWS |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2010 |
| List of Research Outputs |
| Chan K.Y.C., Mak J.C.W., Man R.Y.K. and Vanhoutte P.M.G.R., Endothelium-derived NO is Required for Contraction to Hypoxia in Porcine Coronary Arteries, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 176. |
| Chan K.Y.C., Mak J.C.W., Man R.Y.K. and Vanhoutte P.M.G.R., Hypoxic endothelium-dependent contractions of the porcine coronary artery requires activation of both nitric oxide synthase and soluble guanylyl cyclase, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 17. |
| Kong B.W.C., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Female Apolipoprotein E-deficient Mice are Protected Against the Development of Endothelial Dysfunction with Ageing, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 148. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., 17bEstradiol acutely improves endothelial dysfunction associated with ageing, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 28. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Endothelium Dependent Relaxations Are Improved by Acute Treatment of 17bestradiol in Atherosclerotic Mice with Ageing , 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 180. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Female apolipoproteinE-deficient mice are protected against the development of endothelial dysfunction with ageing, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Lau Y.T., Leung S.W.S. and Man R.Y.K., Modulation of vascular reactivity by kaempferol in porcine coronary arteries, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Leung S.W.S., Chan M.L.Y., Man G.S.K. and Man R.Y.K., Inhibition of cyclooxygenase activity improves endothelium-dependent relaxation in mesenteric arteries ovariectomized rats following chronic inhibition of nitric oxide synthase, 16th World Congress of Pharmacology and Clinical Pharmacology, July 17-23, 2010 Copenhagen, Denmark. 2010. |
| Leung S.W.S., Man G.S.K. and Man R.Y.K., Long-term administration of rutin, a dietary flavonoid, increases the hypotensive actions of acetylcholine in spontaneously hypertensive rats., Acta Physiologica, Official Journal of the Federation of European Physiological Societies, Abstracts for the 12th Symposium on Vascular Neuroeffector Mechanisms. July 24-26, 2010. Odense, Denmark. . 2010, 199: 33. |
| Liang C., Man R.Y.K., Xu A. and Vanhoutte P.M.G.R., Toll-Like Receptor 4 Mutation Alleviates Endothelial Dysfunction in Genetically Obese Mice, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 183. |
| Lin A.H.Y., Leung G.P.H., Leung S.W.S. and Man R.Y.K., The Ligand Binding Properties of Human Membrane Estrogen Receptors, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 415. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S. and Man R.Y.K., ER46 is the predominant membrane estrogen receptor at physiological estrogen level in human, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 17. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Genistein enhances relaxation of the spontaneously hypertensive rat aorta by transactivation of epidermal growth factor receptor following binding to membrane estrogen receptors-a and activation of a G protein-coupled, endothelial nitric oxide synthase-dependent pathway, Pharmacological Research. 2010, 63: 181-189. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S. and Man R.Y.K., The ligand binding properties of human membrane estrogen receptors, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Man R.Y.K., Man G.S.K. and Leung S.W.S., Long-term administration of rutin, a dietary flavonoid, increases the hypotensive actions of acetylcholine in spontaneously hypertensive rats, 12th Symposium of Vascular Neuroeffector Mechanisms, Odense, Denmark. 2010. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Beneficial Vascular Effect of a Non-selective PPAR Activator in Aorta of Spontaneously Hypertensive Rats, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 186. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Involvement of AMPK in the beneficial vascular effect of a non-selective PPAR activator in aorta of spontaneousley hypertensive rats, Experimental Biology, Washington, DC, USA, April 9-13, 2011. 259. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Vascular effect of a non-selective PPAR activator in aorta of spontaneously hypertensive rats, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November, 2010. 32. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine protects endothelial cells from oxidative stress, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Sceintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 77. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine shows protective effct on endothelial cells in oxidative stress, Experimental Biology, Washington DC USA, April 9-13, 2011. 183. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective Effect of Ergothioneine on Endothelial Cells against Oxidative Stress, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2011. 2010, 93. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y...W..., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective effect of ergothioneine on ednothelial cell against oxidative stress, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20-21 November 2010. 34. |
| Wong E.S.W., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., Both D- and L-arginine Increase Contractions to Dexmedetomidine in the Presence of L-name in the Rat Aorta with Endothelium, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 658. |
| Wong S.K., Man R.Y.K. and Vanhoutte P.M.G.R., Chronic Treatment of Vitamin D Derivatives Reduce Endothelium-dependent Contractions in the Aorta of the Spontaneously Hypertensive Rat, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 659. |
| Wong S.K., Delansorne R., Man R.Y.K., Svenningsen P. and Vanhoutte P.M.G.R., Chronic treatment with vitamin D lowers arterial blood pressure and reduces endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat, Am J Physiol Heart Circ Physiol. 2010, 299: H1226-H1234. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., Dexmedetomidine induces both relaxations and contractions, via different a2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat, Journal of Pharmacology and Experimental Therapeutics. 2010, 335. No. 3: 659-664. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., L-Arginine and Arginase Products Increase Endothelium-Dependent Contractions of The Rat Aorta to Dexmedetomidine in The Presence of L-Name, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 20. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., L-arginine and Arginase Products Increase Contractions to Dexmedetomidine in the Rat Aorta with Endothelium, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 187. |
| Yeung Y.T., Leung S.W.S. and Man R.Y.K., Study of vascular effects of protease inhibitors and non-nucleside reverse transcriptase inhibitors on mesenteric arteries, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November 2010. 38. |
| Zhang Y., Leung S.W.S. and Man R.Y.K., Gender-Specific Relaxation of Flavonoids in Rat Mesenteric Arteries, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 81. |
| Zhang Y., Leung S.W.S. and Man R.Y.K., Gender-specific relaxation effects of luteoin in rat mesenteric arteries, Experimental Biology, Washington, DC USA, April 9-13, 2011. 184. |
| Zheng X., Ying L., Liu J., Dou D., He Q., Leung S.W.S., Man R.Y.K., Vanhoutte P.M.G.R. and Gao Y., Role of sulfhydryl-dependent dimerization of soluble guanylyl cyclase in relaxation of porcine coronary artery to nitric oxide, Cardiovasc Research . 2011, 90: 565-572. |
| Researcher : Ng JKF |
| Project Title: | Effect of non-steroidal anti-inflammatory agents on platelet function and blood loss in patients undergoing major joint replacement surgery |
| Investigator(s): | Ng JKF, Chiu PKY, Tang WM |
| Department: | Anaesthesiology |
| Source(s) of Funding: | Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme |
| Start Date: | 10/2007 |
| Project Title: | Effect of desmopressin on platelet dysfunction associated with mild hypothermia in healthy volunteers |
| Investigator(s): | Ng JKF, Cheung CW |
| Department: | Anaesthesiology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2009 |
| Completion Date: | 11/2011 |
| Project Title: | Vascular effects of dexmedetomidine |
| Investigator(s): | Ng JKF, Leung GPH, Vanhoutte PMGR |
| Department: | Anaesthesiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| List of Research Outputs |
| Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats, Anesth Analg. 2011, 112: S-01-S-418. |
| Wong E.S.W., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., Both D- and L-arginine Increase Contractions to Dexmedetomidine in the Presence of L-name in the Rat Aorta with Endothelium, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 658. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., Dexmedetomidine induces both relaxations and contractions, via different a2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat, Journal of Pharmacology and Experimental Therapeutics. 2010, 335. No. 3: 659-664. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., L-Arginine and Arginase Products Increase Endothelium-Dependent Contractions of The Rat Aorta to Dexmedetomidine in The Presence of L-Name, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 20. |
| Researcher : Qu C |
| List of Research Outputs |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Beneficial Vascular Effect of a Non-selective PPAR Activator in Aorta of Spontaneously Hypertensive Rats, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 186. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Involvement of AMPK in the beneficial vascular effect of a non-selective PPAR activator in aorta of spontaneousley hypertensive rats, Experimental Biology, Washington, DC, USA, April 9-13, 2011. 259. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Vascular effect of a non-selective PPAR activator in aorta of spontaneously hypertensive rats, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November, 2010. 32. |
| Researcher : Sit SM |
| List of Research Outputs |
| Li R.W.S., Yang C., Sit S.M., Lin Y.T., Ho Y.W. and Leung G.P.H., Physiological and pharmacological roles of vascular nucleoside transporters, Fourth Scientific Meeting of the Asian Society for Vascular Biology, 20 November 2010. 12. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine protects endothelial cells from oxidative stress, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Sceintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 77. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine shows protective effct on endothelial cells in oxidative stress, Experimental Biology, Washington DC USA, April 9-13, 2011. 183. |
| Sit S.M., Ho Y.W., Li R.W.S., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Potential Beneficial Effect of Ergothioneine in Protecting Endothelial Dysfunction, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 583. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective Effect of Ergothioneine on Endothelial Cells against Oxidative Stress, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2011. 2010, 93. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y...W..., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective effect of ergothioneine on ednothelial cell against oxidative stress, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20-21 November 2010. 34. |
| Researcher : Sit SM |
| List of Research Outputs |
| Li R.W.S., Yang C., Sit S.M., Lin Y.T., Ho Y.W. and Leung G.P.H., Physiological and pharmacological roles of vascular nucleoside transporters, Fourth Scientific Meeting of the Asian Society for Vascular Biology, 20 November 2010. 12. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine protects endothelial cells from oxidative stress, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Sceintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 77. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine shows protective effct on endothelial cells in oxidative stress, Experimental Biology, Washington DC USA, April 9-13, 2011. 183. |
| Sit S.M., Ho Y.W., Li R.W.S., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Potential Beneficial Effect of Ergothioneine in Protecting Endothelial Dysfunction, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 583. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective Effect of Ergothioneine on Endothelial Cells against Oxidative Stress, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2011. 2010, 93. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y...W..., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective effect of ergothioneine on ednothelial cell against oxidative stress, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20-21 November 2010. 34. |
| Researcher : Tang EHC |
| Project Title: | The role of EP4 in inflammation of adipose tissue |
| Investigator(s): | Tang EHC, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 08/2010 |
| List of Research Outputs |
| Rocha V.Z., Sheikine Y., Christen T., Folco E., Sukhova G., Tang E.H.C., Luster A. and Libby P., CXCR3 controls T cell accumulation in fat accumulation, American Heart Association USA 17 November 2010. |
| Tang E.H.C., Anti-inflammatory role of prostaglandin E receptor (EP4) in atherosclerosis, aneurysms and obesity., Department of Anatomy Seminar, HKU 12 March 2011. 2011. |
| Tang E.H.C., Shvartz E., Shimizu K., Rocha V.Z., Zheng C., Fukuda D., Shi G.P., Sukhova G. and Libby P., Deficiency of EP4 Reeptor on Bone Marrow-Derived Cells Boosted Inflammation and Abdominal Aortic Aneurysm Formation induced by Angiotensin II in Hyperlipidemic Mice, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December, 2010. 18:2: 63. |
| Tang E.H.C., Deficiency of EP4 receptor on bone marrow-derived cells boosted inflammation and abdominal aortic aneurysm formation, 14th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine 18 December 2010, Hong Kong Convention and Exhibition Center.. 2010. |
| Tang E.H.C., Shvartz E., Shimizu K., Rocha V.Z., Zheng C., Fukuda D., Shi G.P., Sukhova G. and Libby P., Deletion of EP4 on bone marrow-derived cells enhances inflammation and angiotensin II-induced abdominal aortic aneurysm formation, Arterioscler Thromb Vasc Biol. 2010, 31: 261-9. |
| Tang E.H.C., Shimizu K., Christen T., Rocha V.Z., Shvartz E., Tesmenitsky Y., Sukhova G., Shi G.P. and Libby P., Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions, Cardiovasc Res. 2010, 89: 234-43. |
| Tang E.H.C., Prostaglandin EP4 receptor: A promising therapeutic target for cardiovascular and other inflammatory diseases., Sixth International Symposium on Healthy Aging: A New Golden Age 5-6 March 2011. 2011. |
| Researcher : Tang HC |
| Project Title: | The role of EP4 in inflammation of adipose tissue |
| Investigator(s): | Tang EHC, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 08/2010 |
| List of Research Outputs |
| Researcher : Tom WM |
| Project Title: | VII World Conference on Clinical Pharmacology and Therapeutics 4th Congress of the European Association for Clinical Pharmacology and Therapeutics Antidotal Mechanisms of Hydroxyacetone and Dihydroxyacetone in the Treatment of Acute Acetonitrile Poisoning |
| Investigator(s): | Tom WM |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 07/2000 |
| Researcher : Vanhoutte P.M.G. |
| Project Title: | Annual Summer School in Danish Cardiovascular Research Academy Veins in health and disease |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 06/2007 |
| Project Title: | Causes of Dysfunction in Regenerated Endothelium |
| Investigator(s): | Vanhoutte PMGR, Tse HF |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2008 |
| Completion Date: | 08/2010 |
| Project Title: | Visiting Research Professors Scheme 2009-10 |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | Visiting Research Professors Scheme |
| Start Date: | 09/2009 |
| Project Title: | A Study of the Relative Significance of Nitric Oxide Synthase vs NADPH oxidase in Endothelial Senescence |
| Investigator(s): | Vanhoutte PMGR, Wang Y |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2009 |
| Project Title: | Molecular Pharmacology of G Protein-coupled Receptors 2010 Meeting G-protein dysfunction in regenerated endothelium |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 12/2010 |
| Completion Date: | 12/2010 |
| List of Research Outputs |
| Li Z., Wang Y... and Vanhoutte P...M...G..., Epigallocatechin gallate elicits contractions of the isolated aorta of the aged spontaneously hypertensive rat, Basic & Clinical Pharmacology & Toxicology. 2011, 2011: 1742-7843. |
| Researcher : Vanhoutte PMGR |
| Project Title: | Annual Summer School in Danish Cardiovascular Research Academy Veins in health and disease |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 06/2007 |
| Project Title: | Causes of Dysfunction in Regenerated Endothelium |
| Investigator(s): | Vanhoutte PMGR, Tse HF |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2008 |
| Completion Date: | 08/2010 |
| Project Title: | Visiting Research Professors Scheme 2009-10 |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | Visiting Research Professors Scheme |
| Start Date: | 09/2009 |
| Project Title: | A Study of the Relative Significance of Nitric Oxide Synthase vs NADPH oxidase in Endothelial Senescence |
| Investigator(s): | Vanhoutte PMGR, Wang Y |
| Department: | Pharmacology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2009 |
| Project Title: | Molecular Pharmacology of G Protein-coupled Receptors 2010 Meeting G-protein dysfunction in regenerated endothelium |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 12/2010 |
| Completion Date: | 12/2010 |
| List of Research Outputs |
| Chan C.K.Y., Mak J.C.W. and Vanhoutte P.M.G.R., Secretoneurin Induces Endothelium-dependent Relaxation of the Porcine Coronary Artery, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 222. |
| Chan K.Y.C., Mak J.C.W., Man R.Y.K. and Vanhoutte P.M.G.R., Endothelium-derived NO is Required for Contraction to Hypoxia in Porcine Coronary Arteries, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 176. |
| Chan K.Y.C., Mak J.C.W., Man R.Y.K. and Vanhoutte P.M.G.R., Hypoxic endothelium-dependent contractions of the porcine coronary artery requires activation of both nitric oxide synthase and soluble guanylyl cyclase, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 17. |
| Chan K.Y.C. and Vanhoutte P.M.G.R., Secretoneurin facilitates endothelium-dependent relaxations in porcine coronary arteries, Am J Physiol Heart Circ Physiol. 2011, 300: H1159-H1165. |
| Chang J., Li Y., Huang Y., Lam K.S.L., Hoo R.L.C., Wong W.T., Cheng K.Y., Wang Y., Vanhoutte P.M.G.R. and Xu A., Adiponectin prevents diabetic premature senescence of endothelial progenitor cells and promotes endothelial repair by suppressing the p38 MAP kinase/p16INK4A signaling pathway, Diabetes. 2010, 59: 2949-59. |
| Cohen R.A., Feletou M., Vanhoutte P.M.G.R. and Verbeuren T.J., TP Receptors and Oxidative Stress: Hand in Hand from Endothelial Dysfunction to Atherosclerosis, Advances in Pharmacology. 2010, 60: 85-106. |
| Hansen P.B., Hristovska A., Wolff H., Vanhoutte P.M.G.R., Jensen B.L. and Bie P., Uridine adenosine tetraphosphate affects contractility of mouse aorta and decreases blood pressure in conscious rats and mice, Acta Physiologica. 2010, 200: 171-179. |
| Kong B.W.C., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Female Apolipoprotein E-deficient Mice are Protected Against the Development of Endothelial Dysfunction with Ageing, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 148. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., 17bEstradiol acutely improves endothelial dysfunction associated with ageing, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 28. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Endothelium Dependent Relaxations Are Improved by Acute Treatment of 17bestradiol in Atherosclerotic Mice with Ageing , 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 180. |
| Kong W.C.B., Man R.Y.K., Vanhoutte P.M.G.R. and Leung S.W.S., Female apolipoproteinE-deficient mice are protected against the development of endothelial dysfunction with ageing, 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Lee M.Y.K., Li A.H., Xiao Y., Zhou Z...G., Xu A. and Vanhoutte P.M.G.R., Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells, British Journal of Pharmacology. 2011, (2011) 162: 1564-1576. |
| Lee M.Y.K. and Vanhoutte P.M.G.R., Inflammation and endothelial dysfunction with aging, Endothelial Dysfunction and Inflammation. 2010, 189-200. |
| Li F.Y.L., Cheng K.Y., Lam K.S.L., Vanhoutte P.M.G.R. and Xu A., Cross-talk Between Adipose Tissue And Vasculature: Role Of Adiponectin, Acta Physiologica. 2010. |
| Li Z. and Vanhoutte P.M.G.R., Up-Regulation of heme oxygenase-1 Improves endothelial functions by impairing endothelium-dependent contractions and enhancing endothelium-dependent hyperpolarizations , Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science & Mediicine, 18 December2010. 66, 18:2. |
| Li Z. and Vanhoutte P.M.G.R., Up-regulation of Heme Oxygenase-1 Impairs Endothelium-dependent Contractions, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 87. |
| Li Z. and Vanhoutte P.M.G.R., Up-regulation of heme oxygenase-1 improves endothelial function in arteries of the spontaneously hypertensive rat, Fourth Scientific Meeting of the Asian Society Vascular Biology, Hong Kong, 20 November 2010. 29. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Loss of function in toll-like receptor 4 receptors nitric oxide-mediated relaxations in Leprdb/dbmice, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 63. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Loss-of-function in Toll-like receptor 4 (TLR4) alleviates metabolic syndrome and endothelial dysfunction in genetically obese mice., Acta Physiologica, Official Journal of the Federation of European Physiological Societies, Abstracts for the 12th Symposium on Vascular Neuroeffector Mechanisms. July 24-26, 2010. Odense, Denmark. . 2010, 199: 15. |
| Liang C., Man R.Y.K., Xu A. and Vanhoutte P.M.G.R., Toll-Like Receptor 4 Mutation Alleviates Endothelial Dysfunction in Genetically Obese Mice, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 183. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Toll-like Receptor 4 Mediates the Vasoconstrictor Response Initiated by Adipose Tissue in Mice Arteries, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 413. |
| Lin H.Y.A., Leung G.P.H., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Genistein enhances relaxation of the spontaneously hypertensive rat aorta by transactivation of epidermal growth factor receptor following binding to membrane estrogen receptors-a and activation of a G protein-coupled, endothelial nitric oxide synthase-dependent pathway, Pharmacological Research. 2010, 63: 181-189. |
| Liu J., Zu Y., Lam K.S.L., Lee M.Y.K., Vanhoutte P.M.G.R., Xu A. and Wang Y., SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aorteic Endothelial Cells, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 184. |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Mao X., Ng J.K.F., Irwin M.G., Vanhoutte P.M.G.R. and Xia Z., N-Acetylcysteine Enhances Cardiac HO-1 Protein Expression and Antioxidant Capacity in Diabetic Rats, Anesthesiology. 2010, 112: in press. |
| Ngan E.S.W., Garcia-Barcelo M.M., Lang B.H.H., Vanhoutte P.M.G.R., Tam P.K.H. and Xu J., A risk assessment kit for goiter and thyroid cancer, Collaboration Agreement with Guangzhou Surexam Bio-Tech Co. Ltd. 2010. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Beneficial Vascular Effect of a Non-selective PPAR Activator in Aorta of Spontaneously Hypertensive Rats, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 186. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Involvement of AMPK in the beneficial vascular effect of a non-selective PPAR activator in aorta of spontaneousley hypertensive rats, Experimental Biology, Washington, DC, USA, April 9-13, 2011. 259. |
| Qu C., Leung S.W.S., Vanhoutte P.M.G.R. and Man R.Y.K., Vascular effect of a non-selective PPAR activator in aorta of spontaneously hypertensive rats, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November, 2010. 32. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine protects endothelial cells from oxidative stress, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Sceintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 77. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Vanhoutte P.M.G.R. and Leung G.P.H., Ergothioneine shows protective effct on endothelial cells in oxidative stress, Experimental Biology, Washington DC USA, April 9-13, 2011. 183. |
| Sit S.M., Ho Y.W., Li R.W.S., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Potential Beneficial Effect of Ergothioneine in Protecting Endothelial Dysfunction, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 583. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y.W., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective Effect of Ergothioneine on Endothelial Cells against Oxidative Stress, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2011. 2010, 93. |
| Sit S.M., Ho Y.W., Li R.W.S., Man R.Y.K., Kwan Y...W..., Hausman M., Vanhoutte P.M.G.R. and Leung G.P.H., Protective effect of ergothioneine on ednothelial cell against oxidative stress, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20-21 November 2010. 34. |
| Sudano I.S.A.B.E.L.L.A., Flammer A.N.D.R.E.A.S. .J., Periat D.A.N.I.E.L., Enseleit F.R.A.N.K., Hermann M.A.T.T.H.I.A.S., Wolfrum M.A.T.H.I.A.S., Hirt A.S.T.R.I.D., Kaiser P.R.I.S.K.A., Hurlimann D.A.V.I.D., Neidhart M.I.C.H.E.L., Gay S.T.E.F.F.E.N., Holzmeister J.O.H.A.N.N.E.S., Nussberger J.U.E.R.G., Mocharla P.A.V.A.N.I., Landmesser U.L.F., Haile S.A.R.A.H. .R., Corti R.O.B.E.R.T.O., Vanhoutte P.M.G.R., Luscher T.H.O.M.A.S. .F., Noll G.E.O.R.G. and Ruschitzka F.R.A.N.K., Acetaminophen Increases Blood Pressure in Patients With Coronary Artery Disease, Circulation. 2010, 122: 1789-1796. |
| Vanhoutte P.M.G.R., Endothelium-Dependent Contractions in Hypertension: When Prostacyclin Becomes Ugly, Hypertension. 2011, 57: 526-531. |
| Vanhoutte P.M.G.R., Lee M.Y.K., Wang Y. and Tse H.F., Genomic Changes Caused by Chronic Exposure to High Cholesterol or Fish Oil in Native and Regenerated Porcine Coronary Endothelial Cells, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 633-634. |
| Vanhoutte P.M.G.R., Regeneration of the Endothelium in Vascular Injury, Cardiovasc Drugs Ther. 2010, 24: 299-303. |
| Vanhoutte P.M.G.R., The 50-Years IUPHAR Anniversary Lecture: Regenerate to be Old, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 2. |
| Wang Y., Xu C., Vanhoutte P.M.G.R., Lam K.S.L. and Xu A., Modulation of SIRT1 activity in adipose tissue alters systemic energy homeostasis and insulin sensitivity, American Diabetes Association 71th Scientific Sessions. 2011. |
| Wang Y., Liang Y. and Vanhoutte P.M.G.R., SIRT1 and AMPK in regulating mammalian senescence: A critical review and a working model. , FEBS Letters. 2010. |
| Wong E.S.W., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., Both D- and L-arginine Increase Contractions to Dexmedetomidine in the Presence of L-name in the Rat Aorta with Endothelium, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 658. |
| Wong S.K. and Vanhoutte P.M.G.R., COX-mediated endothelium-dependent contractions: from the past to recent discoveries, Acta Pharmacologica Sinica. 2010, 31: 1095-1102. |
| Wong S.K., Man R.Y.K. and Vanhoutte P.M.G.R., Chronic Treatment of Vitamin D Derivatives Reduce Endothelium-dependent Contractions in the Aorta of the Spontaneously Hypertensive Rat, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 659. |
| Wong S.K., Delansorne R., Svenningsen P. and Vanhoutte P.M.G.R., Chronic Treatment with Vitamin D Lowers Arterial Blood Pressure And Reduces Endothelium-Dependent Contractions in The Aorta of The Spontaneously Hypertensive Rat, Fourth Scientific Meeting of The Asian Society for Vascular Biology, Hiong Kong, 20 November 2010. 22. |
| Wong S.K., Delansorne R., Man R.Y.K., Svenningsen P. and Vanhoutte P.M.G.R., Chronic treatment with vitamin D lowers arterial blood pressure and reduces endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat, Am J Physiol Heart Circ Physiol. 2010, 299: H1226-H1234. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., Dexmedetomidine induces both relaxations and contractions, via different a2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat, Journal of Pharmacology and Experimental Therapeutics. 2010, 335. No. 3: 659-664. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., L-Arginine and Arginase Products Increase Endothelium-Dependent Contractions of The Rat Aorta to Dexmedetomidine in The Presence of L-Name, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 20. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., L-arginine and Arginase Products Increase Contractions to Dexmedetomidine in the Rat Aorta with Endothelium, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 187. |
| Wong W.I.N.G. .T.A.K., Tian X.I.A.O. .Y.U., Chen Y.A.N.G.C.H.A.O., Leung F.U.N.G. .P.I.N.G., Liu L.I.M.E.I., Lee H.U.N.G. .K.A.Y., Ng C.H.I. .F.A.I., Xu A., Yao X.I.A.O.Q.I.A.N.G., Vanhoutte P.M.G.R., Tipoe G.L. and Huang Y.U., Bone Morphogenic Protein-4 Impairs Endothelial Function Through Oxidative Stress-Dependent Cyclooxygenase-2 Upregulation Implications on Hypertension, Circulation Research. 2010, 107: 984-991. |
| Wong W.T., Tian X.Y., Chen Y., Leung F.P., Liu L., Lee H.K., Ng C.F., Xu A., Yao X., Vanhoutte P.M.G.R., Tipoe G.L. and Huang Y., Bone morphogenic protein-4 impairs endothelial function through oxidative stress dependent cyclooxygenase-2 upregulation: Iplications on hypertension, Circulation Research. 2010, 107: 984-991. |
| Wu H., Wu W., Lau C.P., Vanhoutte P.M.G.R. and Li G.R., Use-dependent block of hKv1.5 channels and the molecular determinant by the natural flavone acacetin, 16th Medical Research Conference, Department of Medicine, HKU. 2011, 17(1): 60. |
| Xia Z. and Vanhoutte P.M.G.R., Nitric oxide and protection against cardiac ischemia, Current Pharmaceutical Design. 2011, 17(18): 1774-1782. |
| Xu A., Wang Y., Lam K.S.L. and Vanhoutte P.M.G.R., Vascular actions of adipokines molecular mechanisms and therapeutic implications, Adv Pharmacol. 2010, 60: 229-55. |
| Xu A., Wang Y., Lam K.S.L. and Vanhoutte P.M.G.R., Vascular actions of adipokines: Molecular mechanisms and therapeutic implications., Advances in Pharmacology. 2010, 60: 229-255. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Law K.M., Zhou M. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/ Reperfusion Injury, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 188. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Tse H.F. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/Reperfusion Injury, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 66. |
| Yeung Y.T., Lee S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Vascular Effects of Protease Inhibitors and Non-nucleoside Reverse Transcriptase Inhibitors, the Major Components of Highly Active Antiretroviral Therapy [HAART], 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 97. |
| Yeung Y.T., Lee S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Vascular effects of protease inhibitors and non-nucleoside reverse transcriptase inhibitors, the major components of highly active antiretroviral therapy [HAART], 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Zhao Y., Leung S.W.S. and Vanhoutte P.M.G.R., Endothelial Nos-Independent Release of Nitric-Oxide in the Aorta of the Spontaneously Hypertensive Rat, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 72. |
| Zhao Y., Leung S.W.S. and Vanhoutte P.M.G.R., Previous exposure to nitric oxide inhibits subsequent contractions evoked by prostaglandin E2, prostaglandin D2 and prostaglandin F2a, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November, 2010. 33. |
| Zheng X., Ying L., Liu J., Dou D., He Q., Leung S.W.S., Man R.Y.K., Vanhoutte P.M.G.R. and Gao Y., Role of sulfhydryl-dependent dimerization of soluble guanylyl cyclase in relaxation of porcine coronary artery to nitric oxide, Cardiovasc Research . 2011, 90: 565-572. |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptor contributes to acetylcholine-induced endothelium-dependent relaxations in rat aorta, Experimental Biology, Washington, DC USA, April 9-13, 2011. 184. |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptors contributes to acetylcholine-induced endothelium-dependent relaxations in the aorta of the spontaneous hypertensive rat, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scieintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 72. |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptors contributes to endothelium-dependent relaxations to acetylcholine in the aorta of the spontaneously hypertensive rat, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November 2010. 36. |
| Zou Q. and Vanhoutte P.M.G.R., Vitamin D3 Does not Augment Edhf-mediated Relaxations to Bradykinin, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 692. |
| Researcher : Wang Y |
| Project Title: | Molecular mechanisms underlying the hepato-protective functions of the fat cell-derived hormone adiponectin: potential roles of uncoupling protein 2 |
| Investigator(s): | Wang Y, Xu A |
| Department: | Biochemistry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | Elucidation of the molecular mechanisms underlying endothelial aging using integrated proteomic profiling approaches |
| Investigator(s): | Wang Y, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2009 |
| Completion Date: | 09/2010 |
| Project Title: | Discovery of novel inhibitors targeting lipocalin-2 for the treatment of obesity-related diabetes and cardiovascular diseases |
| Investigator(s): | Wang Y, Vanhoutte PMGR, Xu A |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 06/2010 |
| Completion Date: | 05/2011 |
| Project Title: | Lipocalin-2 and myocardial remodeling in response to ischemia-reperfusion injury |
| Investigator(s): | Wang Y, Vanhoutte PMGR, Xu A |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2010 |
| Completion Date: | 06/2011 |
| Project Title: | Protective effect of lipocalin-2 deficiency on aging- and dietary obesity-induced endothelial dysfunction |
| Investigator(s): | Wang Y, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | Outstanding Young Researcher Award 2009-10 |
| Investigator(s): | Wang Y |
| Department: | Pharmacology |
| Source(s) of Funding: | Outstanding Young Researcher Award |
| Start Date: | 12/2010 |
| Project Title: | 10th International Symposium on Resistance Arteries SIRT1 and AMPK: the Seesaw Effect in Regulating Endothelial Senescence |
| Investigator(s): | Wang Y |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| Project Title: | YY1 as a negative regulator of WNT1 gene expression: a role in mammary carcinogenesis |
| Investigator(s): | Wang Y, Xu A |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2011 |
| List of Research Outputs |
| Bai B. and Wang Y., The use of lorcaserin in the management of obesity: a critical appraisal. , Drug Design, Development and Therapy.. 2010, 5: 1-7. |
| Deng Y., Lam S.S.Y., Meyer U., Feldon J., Li Q., Wei R., Luk L.H.F., Chua S.E., Sham P.C., Wang Y. and McAlonan G.M., Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation, PLoS One . 2011, 6 (2): e16638. |
| Fan P., Chow H.M., Xu A. and Wang Y., Stromal-tumor Interactions Mediated by Lipocalin-2, a Pro-inflammatory Adipokine, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 159. |
| Gao X., Li K., Hui X., Kong X., Sweeney G., Wang Y., Xu A., Teng M., Liu P. and Wu D., Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase, Biochem J. 2011, 435(3): 723-32. |
| Ge X., Chen C., Hui X., Wang Y., Lam K.S.L. and Xu A., Fibroblast Growth Factor-21 Promotes Glucose Uptake through Activation of the serum response factor (SRF)/ Ets-like protein-1 (Elk-1) signaling cascade in Adipocytes, ADA 2011. |
| Herath M.T.D.K.H., Wang Y., Seneviratne C.J., Darveau R., Wong C.Y. and Jin L.J., IADR/Lion Dental Research Award for Junior Investigator (co-author) for P. gingivalis LPS heterogeneity modulates Immuno-inflammatory response in gingival fibroblasts, International Association for Dental Research (IADR), 88th General Session and Exhibition, Barcelona, Spain, July, 2010. 2010. |
| Herath Mudiyanselage T.D.K.H., Wang Y., Seneviratne C.J., Darveau R.P., Wang C.Y. and Jin L.J., Systems biology unravels novel biomarkers in heterogeneous PgLPS-HGF interaction, Journal of Dental Research. 2011, 90 (Spec Iss A): 2983. |
| Jang Y., Lee J., Wang Y. and Sweeney G., Emerging Clinical and Experimental Evidence for the Role ofLipocalin-2 in Metabolic Syndrome., Clin Exp Pharmacol Physiol. 2011. |
| Liu J., Xu A. and Wang Y., Adiponectin deficiency accelerates breast cancer development and promotes cholesterol accumulation in mammary tumors of MMTV-Polyomavirus Middle T Antigen mice, 33nd Annual CTRC-AACR San Antonio Breast Cancer Symposium. San Antonio, Texas, USA, 2010. |
| Liu J., Xu A., Lam K.S.L. and Wang Y., Deficiency of Adiponectin, a Hormone Selectively Secreted from Fat Cells, Accelerated Breast Cancer Development and Promoted Cholesterol Accumulation in Mammary Tumors of MMTV-Polyomavirus Meiddle T Antigen Mice, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 230. |
| Liu J., Zu Y., Lam K.S.L., Lee M.Y.K., Vanhoutte P.M.G.R., Xu A. and Wang Y., SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aorteic Endothelial Cells, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 184. |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Liu X., Huang X., Lin W., Wang D., Diao Y., Li H., Hui X., Wang Y., Xu A., Wu D. and Ke D., New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein, Bioorg Med Chem Lett. 2011, 21(10): 2949-52. |
| Samaranayake Y.H., Cheung B.P.K., Yeung S.K.W., Yau J.Y.Y., Wang Y. and Samaranayake L.P., Fluconazole exposure induces differential regulation of the Candida glabrata proteome, Journal of Dental Research. 2011, 90 (Spec Iss A): 3489. |
| Seneviratne C.J., Wong S.S.W., Wang Y., Jin L.J. and Samaranayake L.P., Phosphoproteomics of candida biofilms, Journal of Dental Research. 2011, 90 (Spec Iss A): 1724. |
| Vanhoutte P.M.G.R., Lee M.Y.K., Wang Y. and Tse H.F., Genomic Changes Caused by Chronic Exposure to High Cholesterol or Fish Oil in Native and Regenerated Porcine Coronary Endothelial Cells, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 633-634. |
| Wang Y., Causative role of lipocalin-2, an inflammatory adipokine, in obesity-related cardiometabolic syndrome., 14th Asia-Oceania Congress of Endocrinology. 2010. |
| Wang Y., Hepatoprotective functions of adiponectin: Indispensible role of uncoupling protein-2., 8th International Diabetes Federation Western Pacific Region Congress. 2010. |
| Wang Y., Journal of Integrated Omics. 2010. |
| Wang Y., Mitochondria dysfunction in metabolic syndrome and cardiovascular disease: role of adipokines, The Croucher Foundation-Advanced Study Institute on Mitochondrial Stress in Diabetes and Aging. 2011. |
| Wang Y., Xu C., Vanhoutte P.M.G.R., Lam K.S.L. and Xu A., Modulation of SIRT1 activity in adipose tissue alters systemic energy homeostasis and insulin sensitivity, American Diabetes Association 71th Scientific Sessions. 2011. |
| Wang Y., Outstanding young researcher award 2010-2011, The University of Hong Kong. 2010. |
| Wang Y., Liang Y. and Vanhoutte P.M.G.R., SIRT1 and AMPK in regulating mammalian senescence: A critical review and a working model. , FEBS Letters. 2010. |
| Wang Y., SIRT1 and AMPK: the seesaw effect in regulating endothelial senescence, 10th International Symposium on Resistance Arteries. 2011. |
| Wang Y., Small lipid-binding proteins in regulating endothelial and vascular functions: focusing on adipocyte fatty acid binding protein and lipocalin-2, Br J Pharmacol. 2011. |
| Wen L., Yang Y., Wang Y., Xu A., Wu D. and Chen Y., Appl1 Is Essential For The Survival Of Xenopus Pancreas, Duodenum, And Stomach Progenitor Cells., Dev Dyn. . 2010, 239: 2198-207. |
| Williams G., Callon K., Watson M., Costa J., Ding Y., Wang Y., Naot D., Reid I. and Cornish J., Skeletal phenotype of the leptin receptor-deficient db/db mouse. , Journal of Bone and Mineral Research. 2011, 26: 1-12. |
| Xu A., Wang Y., Lam K.S.L. and Vanhoutte P.M.G.R., Vascular actions of adipokines molecular mechanisms and therapeutic implications, Adv Pharmacol. 2010, 60: 229-55. |
| Xu A., Wang Y., Lam K.S.L. and Vanhoutte P.M.G.R., Vascular actions of adipokines: Molecular mechanisms and therapeutic implications., Advances in Pharmacology. 2010, 60: 229-255. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Law K.M., Zhou M. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/ Reperfusion Injury, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 188. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Tse H.F. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/Reperfusion Injury, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 66. |
| Ye D., Li F.Y.L., Lam K.S.L., Wang Y. and Xu A., Genetic Inactivation of Toll-Like Receptor 4 Alleviates Diet-induced Nonalcoholic Steatohepatitis by Inhibiting Reactive Oxygen Species-evoked Activation of X-box Binding Protein-1 in ApoE-deficient Mice, ADA 2011. |
| Yu H., Xia F., Lam K.S.L., Wang Y., Bao Y., Zhang J., Gu Y., Zhou P., Lu J., Jai W. and Xu A., Circadian Rhythm of Circulating Fibroblast Growth Factor 21 (FGF21) is Related to Diurnal Changes in Free Fatty Acids in Humans., Clinical Chemistry. 2011. |
| Zhang X., Lam K.S.L., Ye H., Chung S.K., Zhou M., Wang Y. and Xu A., Adipose tissue-specific inhibition of hypoxia-inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice, J Biol Chem. 2010, 285: 32869-77. |
| Zhou M., Xu A., Lam K.S.L., Tam P.K.H., Che C.M., Chan L., Lee I.K., Wu D.H. and Wang Y., Rosiglitazone promotes fatty acyl CoA accumulation and excessive glycogen storage in livers of mice without adiponectin, Journal of Hepatology. 2010, 53(6): 1108-1116. |
| Researcher : Wang Y. |
| Project Title: | Molecular mechanisms underlying the hepato-protective functions of the fat cell-derived hormone adiponectin: potential roles of uncoupling protein 2 |
| Investigator(s): | Wang Y, Xu A |
| Department: | Biochemistry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | Elucidation of the molecular mechanisms underlying endothelial aging using integrated proteomic profiling approaches |
| Investigator(s): | Wang Y, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2009 |
| Completion Date: | 09/2010 |
| Project Title: | Discovery of novel inhibitors targeting lipocalin-2 for the treatment of obesity-related diabetes and cardiovascular diseases |
| Investigator(s): | Wang Y, Vanhoutte PMGR, Xu A |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 06/2010 |
| Completion Date: | 05/2011 |
| Project Title: | Lipocalin-2 and myocardial remodeling in response to ischemia-reperfusion injury |
| Investigator(s): | Wang Y, Vanhoutte PMGR, Xu A |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2010 |
| Completion Date: | 06/2011 |
| Project Title: | Protective effect of lipocalin-2 deficiency on aging- and dietary obesity-induced endothelial dysfunction |
| Investigator(s): | Wang Y, Vanhoutte PMGR |
| Department: | Pharmacology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | Outstanding Young Researcher Award 2009-10 |
| Investigator(s): | Wang Y |
| Department: | Pharmacology |
| Source(s) of Funding: | Outstanding Young Researcher Award |
| Start Date: | 12/2010 |
| Project Title: | 10th International Symposium on Resistance Arteries SIRT1 and AMPK: the Seesaw Effect in Regulating Endothelial Senescence |
| Investigator(s): | Wang Y |
| Department: | Pharmacology |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| Project Title: | YY1 as a negative regulator of WNT1 gene expression: a role in mammary carcinogenesis |
| Investigator(s): | Wang Y, Xu A |
| Department: | Pharmacology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2011 |
| List of Research Outputs |
| Li Z., Wang Y... and Vanhoutte P...M...G..., Epigallocatechin gallate elicits contractions of the isolated aorta of the aged spontaneously hypertensive rat, Basic & Clinical Pharmacology & Toxicology. 2011, 2011: 1742-7843. |
| Researcher : Wong ESW |
| List of Research Outputs |
| Wong E.S.W., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., Both D- and L-arginine Increase Contractions to Dexmedetomidine in the Presence of L-name in the Rat Aorta with Endothelium, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 658. |
| Researcher : Wong SK |
| List of Research Outputs |
| Wong S.K. and Vanhoutte P.M.G.R., COX-mediated endothelium-dependent contractions: from the past to recent discoveries, Acta Pharmacologica Sinica. 2010, 31: 1095-1102. |
| Wong S.K., Man R.Y.K. and Vanhoutte P.M.G.R., Chronic Treatment of Vitamin D Derivatives Reduce Endothelium-dependent Contractions in the Aorta of the Spontaneously Hypertensive Rat, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 659. |
| Wong S.K., Delansorne R., Svenningsen P. and Vanhoutte P.M.G.R., Chronic Treatment with Vitamin D Lowers Arterial Blood Pressure And Reduces Endothelium-Dependent Contractions in The Aorta of The Spontaneously Hypertensive Rat, Fourth Scientific Meeting of The Asian Society for Vascular Biology, Hiong Kong, 20 November 2010. 22. |
| Wong S.K., Delansorne R., Man R.Y.K., Svenningsen P. and Vanhoutte P.M.G.R., Chronic treatment with vitamin D lowers arterial blood pressure and reduces endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat, Am J Physiol Heart Circ Physiol. 2010, 299: H1226-H1234. |
| Researcher : Wong SWE |
| List of Research Outputs |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., Dexmedetomidine induces both relaxations and contractions, via different a2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat, Journal of Pharmacology and Experimental Therapeutics. 2010, 335. No. 3: 659-664. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., L-Arginine and Arginase Products Increase Endothelium-Dependent Contractions of The Rat Aorta to Dexmedetomidine in The Presence of L-Name, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong, 20 November 2010. 20. |
| Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., L-arginine and Arginase Products Increase Contractions to Dexmedetomidine in the Rat Aorta with Endothelium, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 187. |
| Researcher : Xu A |
| Project Title: | Molecular mechanism underlaying the pathogenesis of type 2 diabetes |
| Investigator(s): | Xu A |
| Department: | Medicine |
| Source(s) of Funding: | Matching Fund for National Key Basic Research Development Scheme (973 Projects) |
| Start Date: | 05/2007 |
| Project Title: | APPL1 as a novel modulator of endothelial nitric oxide production and endothelium-dependent vasodilation |
| Investigator(s): | Xu A, Chung SK, Wang Y |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2008 |
| Completion Date: | 12/2010 |
| Project Title: | Vascular dysfunction in obesity and diabetes: from risk prediction to therapeutic intervention |
| Investigator(s): | Xu A, Lam KSL, Vanhoutte PMGR, Tse HF, Wong KB, Wang Y |
| Department: | Medicine |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2008 |
| Project Title: | Adipocyte fatty acid binding protein as a novel diagnostic marker and therapeutic target to combat vascular complications of diabetes: mechanisms and clinical implications |
| Investigator(s): | Xu A, Vanhoutte PMGR, Lam KSL |
| Department: | Medicine |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2009 |
| Project Title: | Protective roles of AMP-activated protein kinase against vascular disease in diabetes: Molecular mechanisms and therapeutic intervention |
| Investigator(s): | Xu A, Vanhoutte PMGR |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | Characterization of Novel Adaptor Proteins Involved in Regulating Insulin Sensitivity and Glucose Homeostasis: from Molecular Mechanism to Physiological Implication |
| Investigator(s): | Xu A |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Characterization of the receptor and postreceptor signaling events underlying the metabolic actions of FGF21, a potential therapeutic agent for treating obesity-related medical complications |
| Investigator(s): | Xu A, Hoo RLC, Wang Y |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2010 |
| Completion Date: | 05/2011 |
| Project Title: | Pharmacological inhibition of adipocyte fatty acid binding protein as a new strategy for treating obesity-related cardio-metabolic disorders |
| Investigator(s): | Xu A, Vanhoutte PMGR, Lam KSL |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 06/2010 |
| Completion Date: | 06/2011 |
| Project Title: | APPL2 as a Negative Regulator of Insulin Sensitivity and Glucose Uptake in Skeletal Muscle: A Novel Pathway Leading to Insulin Resistance? |
| Investigator(s): | Xu A |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2011 |
| Project Title: | Genetic and pathogenic pathways leading to type 2 diabetes Mellitus |
| Investigator(s): | Xu A |
| Department: | Medicine |
| Source(s) of Funding: | Matching Fund for National Key Basic Research Development Scheme (973 Projects) |
| Start Date: | 05/2011 |
| Project Title: | Protective effects of the liver-derived hormone adropin against obesity-related insulin resistance and metabolic disorders |
| Investigator(s): | Xu A, Wang Y |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2011 |
| Project Title: | 71th Scientific Sessions of the American Diabetes Association Genetic Inactivation of Toll-Like Receptor 4 Alleviates Diet-Induced Nonalcoholic Steatohepatitis by Inhibiting Reactive Oxygen Species-Evoked Activation of X-box Binding Protein-1 in ApoE-Deficient Mice |
| Investigator(s): | Xu A |
| Department: | Medicine |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 06/2011 |
| Project Title: | A Multi-disciplinary Approach to Investigate Vascular Dysfunction in Obesity and Diabetes: From Molecular Mechanism to Therapeutic Intervention |
| Investigator(s): | Xu A, Vanhoutte PMGR, Wang Y, Lam KSL |
| Department: | Medicine |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2011 |
| List of Research Outputs |
| Fan P., Chow H.M., Xu A. and Wang Y., Stromal-tumor Interactions Mediated by Lipocalin-2, a Pro-inflammatory Adipokine, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 159. |
| Lee M.Y.K., Li A.H., Xiao Y., Zhou Z...G., Xu A. and Vanhoutte P.M.G.R., Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells, British Journal of Pharmacology. 2011, (2011) 162: 1564-1576. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Loss of function in toll-like receptor 4 receptors nitric oxide-mediated relaxations in Leprdb/dbmice, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 63. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Loss-of-function in Toll-like receptor 4 (TLR4) alleviates metabolic syndrome and endothelial dysfunction in genetically obese mice., Acta Physiologica, Official Journal of the Federation of European Physiological Societies, Abstracts for the 12th Symposium on Vascular Neuroeffector Mechanisms. July 24-26, 2010. Odense, Denmark. . 2010, 199: 15. |
| Liang C., Man R.Y.K., Xu A. and Vanhoutte P.M.G.R., Toll-Like Receptor 4 Mutation Alleviates Endothelial Dysfunction in Genetically Obese Mice, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 183. |
| Liang C., Xu A. and Vanhoutte P.M.G.R., Toll-like Receptor 4 Mediates the Vasoconstrictor Response Initiated by Adipose Tissue in Mice Arteries, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 413. |
| Liu J., Xu A. and Wang Y., Adiponectin deficiency accelerates breast cancer development and promotes cholesterol accumulation in mammary tumors of MMTV-Polyomavirus Middle T Antigen mice, 33nd Annual CTRC-AACR San Antonio Breast Cancer Symposium. San Antonio, Texas, USA, 2010. |
| Liu J., Xu A., Lam K.S.L. and Wang Y., Deficiency of Adiponectin, a Hormone Selectively Secreted from Fat Cells, Accelerated Breast Cancer Development and Promoted Cholesterol Accumulation in Mammary Tumors of MMTV-Polyomavirus Meiddle T Antigen Mice, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 230. |
| Liu J., Zu Y., Lam K.S.L., Lee M.Y.K., Vanhoutte P.M.G.R., Xu A. and Wang Y., SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aorteic Endothelial Cells, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 184. |
| Liu T.C., Xu A., Mak T.W., Liang C., Law K.M., Man R.Y.K., Vanhoutte P.M.G.R. and Wang Y., Lipocalin-2, an Inflammatory Adipokine, Uncouples Endothelial Nitric-oxide Synthase and Enhances Endothelial Dysfunction Caused by Dietary Obesity, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 suppl.1: 159-160. |
| Wang Y., Xu C., Vanhoutte P.M.G.R., Lam K.S.L. and Xu A., Modulation of SIRT1 activity in adipose tissue alters systemic energy homeostasis and insulin sensitivity, American Diabetes Association 71th Scientific Sessions. 2011. |
| Wong S.L., Lau C.W., Wong W.T., Xu A., Au C.L., Yao X. and Huang Y., Co-activation of PKCdelta/ERK1/2 and p38 MAPK mediates angiotensin II-induced cyclooxygenase-2 up-regulation in endothelial cells and the clinical implications, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 149. |
| Wong W.I.N.G. .T.A.K., Tian X.I.A.O. .Y.U., Chen Y.A.N.G.C.H.A.O., Leung F.U.N.G. .P.I.N.G., Liu L.I.M.E.I., Lee H.U.N.G. .K.A.Y., Ng C.H.I. .F.A.I., Xu A., Yao X.I.A.O.Q.I.A.N.G., Vanhoutte P.M.G.R., Tipoe G.L. and Huang Y.U., Bone Morphogenic Protein-4 Impairs Endothelial Function Through Oxidative Stress-Dependent Cyclooxygenase-2 Upregulation Implications on Hypertension, Circulation Research. 2010, 107: 984-991. |
| Wong W.T., Tian X.Y., Chen Y., Leung F.P., Liu L., Lee H.K., Ng C.F., Xu A., Yao X., Vanhoutte P.M.G.R., Tipoe G.L. and Huang Y., Bone morphogenic protein-4 impairs endothelial function through oxidative stress dependent cyclooxygenase-2 upregulation: Iplications on hypertension, Circulation Research. 2010, 107: 984-991. |
| Xu A., Wang Y., Lam K.S.L. and Vanhoutte P.M.G.R., Vascular actions of adipokines: Molecular mechanisms and therapeutic implications., Advances in Pharmacology. 2010, 60: 229-255. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Law K.M., Zhou M. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/ Reperfusion Injury, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 188. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Tse H.F. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/Reperfusion Injury, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 66. |
| Zhou M., Xu A., Lam K.S.L., Tam P.K.H., Che C.M., Chan L., Lee I.K., Wu D.H. and Wang Y., Rosiglitazone promotes fatty acyl CoA accumulation and excessive glycogen storage in livers of mice without adiponectin, Journal of Hepatology. 2010, 53(6): 1108-1116. |
| Researcher : Xu C |
| List of Research Outputs |
| Wang Y., Xu C., Vanhoutte P.M.G.R., Lam K.S.L. and Xu A., Modulation of SIRT1 activity in adipose tissue alters systemic energy homeostasis and insulin sensitivity, American Diabetes Association 71th Scientific Sessions. 2011. |
| Researcher : Yang B |
| List of Research Outputs |
| Yang B., Xu A., Vanhoutte P.M.G.R., Law K.M., Zhou M. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/ Reperfusion Injury, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 188. |
| Yang B., Xu A., Vanhoutte P.M.G.R., Tse H.F. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/Reperfusion Injury, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 66. |
| Researcher : Yang C |
| List of Research Outputs |
| Li R.W.S., Yang C., Sit S.M., Lin Y.T., Ho Y.W. and Leung G.P.H., Physiological and pharmacological roles of vascular nucleoside transporters, Fourth Scientific Meeting of the Asian Society for Vascular Biology, 20 November 2010. 12. |
| Yang C., Kwan Y.W., Au A.L.S., Poon C.C.W., Zhang Q., Chan S.W., Lee S.M. and Leung G.P.H., 14,15-Epoxyeicosatrienoic acid induces vasorelaxation through the prostaglandin EP(2) receptors in rat mesenteric artery, Prostaglandins and Other Lipid Mediator . 2010, 93: 44-51. |
| Yang C., Kwan Y.W., Chan S.W., Lee S.M. and Leung G.P.H., Potentiation of EDHF-mediated relaxation by chloride channel blockers, Acta Pharmacologica Sinica . 2010, 31: 1303-1311. |
| Researcher : Yeung YT |
| List of Research Outputs |
| Yeung Y.T., Leung S.W.S. and Man R.Y.K., Study of vascular effects of protease inhibitors and non-nucleside reverse transcriptase inhibitors on mesenteric arteries, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November 2010. 38. |
| Yeung Y.T., Lee S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Vascular Effects of Protease Inhibitors and Non-nucleoside Reverse Transcriptase Inhibitors, the Major Components of Highly Active Antiretroviral Therapy [HAART], 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 97. |
| Yeung Y.T., Lee S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Vascular effects of protease inhibitors and non-nucleoside reverse transcriptase inhibitors, the major components of highly active antiretroviral therapy [HAART], 16th World Congress of Pharmacology and Clinical Pharmacology, Copenhagen, Denmark. 2010. |
| Researcher : Zhang Y |
| List of Research Outputs |
| Zhang Y., Leung S.W.S. and Man R.Y.K., Gender-Specific Relaxation of Flavonoids in Rat Mesenteric Arteries, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 81. |
| Zhang Y., Leung S.W.S. and Man R.Y.K., Gender-specific relaxation effects of luteoin in rat mesenteric arteries, Experimental Biology, Washington, DC USA, April 9-13, 2011. 184. |
| Researcher : Zhao Y |
| List of Research Outputs |
| Zhao Y., Leung S.W.S. and Vanhoutte P.M.G.R., Endothelial Nos-Independent Release of Nitric-Oxide in the Aorta of the Spontaneously Hypertensive Rat, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scientific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 72. |
| Zhao Y., Leung S.W.S. and Vanhoutte P.M.G.R., Previous exposure to nitric oxide inhibits subsequent contractions evoked by prostaglandin E2, prostaglandin D2 and prostaglandin F2a, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November, 2010. 33. |
| Researcher : Zhou M |
| List of Research Outputs |
| Yang B., Xu A., Vanhoutte P.M.G.R., Law K.M., Zhou M. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/ Reperfusion Injury, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 188. |
| Zhang X., Lam K.S.L., Ye H., Chung S.K., Zhou M., Wang Y. and Xu A., Adipose tissue-specific inhibition of hypoxia-inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice, J Biol Chem. 2010, 285: 32869-77. |
| Zhou M., Xu A., Lam K.S.L., Tam P.K.H., Che C.M., Chan L., Lee I.K., Wu D.H. and Wang Y., Rosiglitazone promotes fatty acyl CoA accumulation and excessive glycogen storage in livers of mice without adiponectin, Journal of Hepatology. 2010, 53(6): 1108-1116. |
| Researcher : Zhou M |
| List of Research Outputs |
| Yang B., Xu A., Vanhoutte P.M.G.R., Law K.M., Zhou M. and Wang Y., Lipocalin-2 Deficiency Protects Hearts Against Ischemia/ Reperfusion Injury, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 188. |
| Zhang X., Lam K.S.L., Ye H., Chung S.K., Zhou M., Wang Y. and Xu A., Adipose tissue-specific inhibition of hypoxia-inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice, J Biol Chem. 2010, 285: 32869-77. |
| Zhou M., Xu A., Lam K.S.L., Tam P.K.H., Che C.M., Chan L., Lee I.K., Wu D.H. and Wang Y., Rosiglitazone promotes fatty acyl CoA accumulation and excessive glycogen storage in livers of mice without adiponectin, Journal of Hepatology. 2010, 53(6): 1108-1116. |
| Researcher : Zou Q |
| List of Research Outputs |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptor contributes to acetylcholine-induced endothelium-dependent relaxations in rat aorta, Experimental Biology, Washington, DC USA, April 9-13, 2011. 184. |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptors contributes to acetylcholine-induced endothelium-dependent relaxations in the aorta of the spontaneous hypertensive rat, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scieintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 72. |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptors contributes to endothelium-dependent relaxations to acetylcholine in the aorta of the spontaneously hypertensive rat, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November 2010. 36. |
| Zou Q. and Vanhoutte P.M.G.R., Vitamin D3 Does not Augment Edhf-mediated Relaxations to Bradykinin, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 692. |
| Researcher : Zou Q |
| List of Research Outputs |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptor contributes to acetylcholine-induced endothelium-dependent relaxations in rat aorta, Experimental Biology, Washington, DC USA, April 9-13, 2011. 184. |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptors contributes to acetylcholine-induced endothelium-dependent relaxations in the aorta of the spontaneous hypertensive rat, Journal of the Hong Kong College of Cardiology, Fourteenth Annual Scieintific Meeting, Institute of Cardiovascular Science and Medicine, 18 December 2010. 18:2: 72. |
| Zou Q. and Vanhoutte P.M.G.R., Activation of nicotinic receptors contributes to endothelium-dependent relaxations to acetylcholine in the aorta of the spontaneously hypertensive rat, Fourth Scientific Meeting of the Asian Society for Vascular Biology, Hong Kong 20-21 November 2010. 36. |
| Zou Q. and Vanhoutte P.M.G.R., Vitamin D3 Does not Augment Edhf-mediated Relaxations to Bradykinin, WorldPharma2010, 16th World Congress on Basic and Clinical Pharmacology, July 17-23, 2010, Copenhagen, Denmark.. 2010, 107 Suppl.1: 692. |
| Researcher : Zu Y |
| List of Research Outputs |
| Liu J., Zu Y., Lam K.S.L., Lee M.Y.K., Vanhoutte P.M.G.R., Xu A. and Wang Y., SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aorteic Endothelial Cells, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 184. |