DEPT OF ANATOMY
| Researcher : Cai Z |
| List of Research Outputs |
| Cai Z., Wang Q., Zhou Y., Zheng L., Chiu J. and He Q.Y., Epidermal growth factor-induced epithelial-mesenchymal transiotion in human esophageal carcinoma cells --a model for the study of metastasis, Cancer Letters. 2010, 296(1): 88-95. |
| Researcher : Chan CWY |
| Project Title: | Interferon-producing killer dendritic cells in infection |
| Investigator(s): | Chan CWY |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 07/2010 |
| Completion Date: | 07/2011 |
| Researcher : Chan KY |
| List of Research Outputs |
| Luo Z., Lai M., Cheung M., Han S., Zhang T., Luo Z., Ting J.W.M., Wong P.W.L., Chan K.Y., So K.F. and Tipoe G.L., Developing local association network based IoT solutions for body parts tagging and tracking, 42 International Journal of Systems and Service-Oriented Engineering. 2010, 1(4): 42-64. |
| Researcher : Chan ML |
| List of Research Outputs |
| Chan M.L., Xu H. and Ching Y.P., Characterization of PAK4 and RhoV in hepatocellular carcinoma (HCC)., In: European Molecular Biology Organization, The EMBO Meeting 2010 Barcelona Spain . 2010. |
| Mak W.Y.G., Chan M.L., Leong V.Y.L., Lee M.F., Yau T.O., Ng I.O.L. and Ching Y.P., Overexpression of a novel activator of PAK4, the CDK5 kinase-associated protein CDK5RAP3, promotes hepatocellular carcinoma metastasis, Cancer Research. 2011, 71: 2949-58. |
| Researcher : Chan TF |
| List of Research Outputs |
| Chan T.F., Chiu K., Lok C.K.M., Lok C.K.M., Ho Y.S., So K.F. and Chang R.C.C., Loss of neurons in the inner retinal neuron of transgenic mice bearing human mutated amyloid precursor protein., Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P25. |
| Chiu K., Chan T.F., Wu A., Leung I.Y.P., So K.F. and Chang R.C.C., Neurodegeneration of the retina in mouse models of Alzheimer’s disease: What can we learn from the retina?, Age. Springer, 2011. |
| Chiu K., Chan T.F., So K.F. and Chang R.C.C., Retinal neurodegeneration in AD transgenic mice, 从AD动物模型研究 视网膜神经细胞退化 , Joint seminar College of life sciences ShenZhen University/ HKU. 2011. |
| Researcher : Chan YK |
| List of Research Outputs |
| Chan Y.K., Hermman Wacker Award, 2010. |
| Researcher : Chang R.C.C. |
| Project Title: | Elucidating the roles of ER stress responses in β-amyloid peptide production and tau phosphorylation as a common pathological pathway |
| Investigator(s): | Chang RCC, So KF |
| Department: | Anatomy |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2008 |
| Completion Date: | 12/2010 |
| Project Title: | Significance of molecular signaling for protein translation control in neurodegeneration of amyotrophic lateral sclerosis |
| Investigator(s): | Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | Liu Po Shan/Dr Vincent Liu Endowment Fund for Motor Neuron diseases - General Award |
| Start Date: | 03/2008 |
| Project Title: | Investigating the efficacy of minocycline as neuroprotective agent against cytokine storm-mediated neurotoxicity |
| Investigator(s): | Chang RCC, Ho YS |
| Department: | Anatomy |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 10/2009 |
| Project Title: | Alzheimer's Disease Conference: From Public Health to Therapeutic Insights |
| Investigator(s): | Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | France/Hong Kong Joint Research Scheme - Conference/Workshop Grants |
| Start Date: | 01/2010 |
| Completion Date: | 12/2010 |
| Project Title: | Elucidating the pathophysiological significance of endoplasmic reticulum aggregation in neurons stressed by ?amyloid peptide and in Alzheimers disease' |
| Investigator(s): | Chang RCC, Wu W |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Establishing a Logistic Screening Platform for Stilbene and its Derivatives from Functional Food as Potential Neuroprotective Drug Leads in Parkinson's Disease |
| Investigator(s): | Chang RCC, Wang M |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 01/2010 |
| Completion Date: | 12/2010 |
| Project Title: | Elucidating the biological mechanisms of transforming autophagy into apoptosis in hippocampal neurons exposed to low molecular weight beta-amyloid peptide |
| Investigator(s): | Chang RCC, Ho YS |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2010 |
| Completion Date: | 03/2011 |
| Project Title: | 10th International Conference of Alzheimer's Disease and Parkinson's Disease (AD/PD 2011) Signaling Mechanism from Endoplasmic Reticulum Collapse to Induction of Autophagy in Neurons Stressed with Low Molecular Weight Beta‐amyloid Peptides |
| Investigator(s): | Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 03/2011 |
| Completion Date: | 03/2011 |
| Project Title: | Elucidating pathophysiological mechanisms of synaptic and axonal degeneration in depression and Alzheimer's disease |
| Investigator(s): | Chang RCC, Ho YS, Law ACK |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Cheung Y...T..., Zhang Q., Hung H.L., Lai S...W..., Yu M...S..., So K...F... and Chang R...C...C..., Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight b-amyloid peptide, Journal of Cellular and Molecular Medicine. 2011, 15(2): 244-257. |
| Researcher : Chang RCC |
| Project Title: | Elucidating the roles of ER stress responses in β-amyloid peptide production and tau phosphorylation as a common pathological pathway |
| Investigator(s): | Chang RCC, So KF |
| Department: | Anatomy |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2008 |
| Completion Date: | 12/2010 |
| Project Title: | Significance of molecular signaling for protein translation control in neurodegeneration of amyotrophic lateral sclerosis |
| Investigator(s): | Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | Liu Po Shan/Dr Vincent Liu Endowment Fund for Motor Neuron diseases - General Award |
| Start Date: | 03/2008 |
| Project Title: | Investigating the efficacy of minocycline as neuroprotective agent against cytokine storm-mediated neurotoxicity |
| Investigator(s): | Chang RCC, Ho YS |
| Department: | Anatomy |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 10/2009 |
| Project Title: | Alzheimer's Disease Conference: From Public Health to Therapeutic Insights |
| Investigator(s): | Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | France/Hong Kong Joint Research Scheme - Conference/Workshop Grants |
| Start Date: | 01/2010 |
| Completion Date: | 12/2010 |
| Project Title: | Elucidating the pathophysiological significance of endoplasmic reticulum aggregation in neurons stressed by ?amyloid peptide and in Alzheimers disease' |
| Investigator(s): | Chang RCC, Wu W |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Establishing a Logistic Screening Platform for Stilbene and its Derivatives from Functional Food as Potential Neuroprotective Drug Leads in Parkinson's Disease |
| Investigator(s): | Chang RCC, Wang M |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 01/2010 |
| Completion Date: | 12/2010 |
| Project Title: | Elucidating the biological mechanisms of transforming autophagy into apoptosis in hippocampal neurons exposed to low molecular weight beta-amyloid peptide |
| Investigator(s): | Chang RCC, Ho YS |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2010 |
| Completion Date: | 03/2011 |
| Project Title: | 10th International Conference of Alzheimer's Disease and Parkinson's Disease (AD/PD 2011) Signaling Mechanism from Endoplasmic Reticulum Collapse to Induction of Autophagy in Neurons Stressed with Low Molecular Weight Beta‐amyloid Peptides |
| Investigator(s): | Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 03/2011 |
| Completion Date: | 03/2011 |
| Project Title: | Elucidating pathophysiological mechanisms of synaptic and axonal degeneration in depression and Alzheimer's disease |
| Investigator(s): | Chang RCC, Ho YS, Law ACK |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Chan T.F., Chiu K., Lok C.K.M., Lok C.K.M., Ho Y.S., So K.F. and Chang R.C.C., Loss of neurons in the inner retinal neuron of transgenic mice bearing human mutated amyloid precursor protein., Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P25. |
| Chang R.C.C., Chairman, Organizing Committee, Croucher Foundation Conference, Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insights, 2011. 2011. |
| Chang R.C.C., Chief Editor, Neurodegeneration. InTech Open Access Publisher, 2011. |
| Chang R.C.C., Collapse of the endoplasmic reticulum facilitates autophagy in Alzheimer's disease, Xiangshan Science Conference on Brain and Cognitive Sciences, Ministry of Science and Technology of China (MOST), Hong Kong. 2011. |
| Chang R.C.C., Direct and Indirect Neurotoxicity: How do we apply the concept into environmental toxin, infectious diseases, and neurodegenerative disease research?, The 1st Shenzhen Preventive Medicine and Toxicology Meeting, Shenzhen Centre for Disease Control and Prevention, Shenzhen, CHINA. 2011. |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime MTOR suppression in low molecular weight Ab induced autophagy, Alzheimer's & Dementia. 2010, 6(4) Supplement: S243. |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime mTOR suppression in low molecular weight Abeta induced autophagy, Alzheimer's and Dementia (Suppl. 1). 2010, S243. |
| Chang R.C.C., Editorial Board Member, American Journal of Alzheimer's Disease and Other Dementia. 2011. |
| Chang R.C.C., Editorial Board Member, Chinese Medicine. 2011. |
| Chang R.C.C., Editorial Board Member, The Open Enzyme Inhibition Journal. 2011. |
| Chang R.C.C., Editorial Board Member, World Journal of Neuroscience. 2011. |
| Chang R.C.C., Editorial Board Memeber, Automated Experimentation. 2011. |
| Chang R.C.C., Editorial Board Memeber, International Journal of Clinical and Experimental Medicine. 2011. |
| Chang R.C.C., Editorial Board member, American Journal of Alzheimer's Disease and Other Dementias. 2010. |
| Chang R.C.C., Editorial Board member, Anatomy and Physiology: Current Research. 2011. |
| Chang R.C.C., Editorial Board member, Journal of Brain and Behavioral Sciences. 2011. |
| Chang R.C.C., Endoplasmic Reticulum as a key intracellular organelle to determine the fate of neurons in Alzheimer's disease, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, CHINA. 2010. |
| Chang R.C.C., From Alzheimer's Disease Research to Understand other Neurodegeneration leading to Dementia: The Commone Modes of Neurodegeneration, AIDS Institute, LKS Faculty of MEdicine, HKU. 2011. |
| Chang R.C.C., From Direct and Indirect Neurotoxicity to Search for Neuroprotective Agents Against Neurodegeneration in Glaucoma, School of Optometry, The Hong Kong Polytechnic University, Hong Kong. 2010. |
| Chang R.C.C., Handling Associate Editor, Journal of Alzheimer's Disease. 2011. |
| Chang R.C.C., Investigating the maturation processes of forming autophagic vacuoles in neurons stressed by beta‐amyloid peptide, Scientific meeting for Cell Biology, Cancer Research Centre, LKS Faculty of Medicine, HKU, Hong Kong. 2010. |
| Chang R.C.C., Mechanisms of Cell Death in Alzheimer's Disease, The Eighth Asia Pacific Multidisciplinary Meeting for Nervous System Diseases, Hong Kong. 2011. |
| Chang R.C.C., Zhang Q., Hung H.L., Wuwongse S. and Ho Y.S., Mechanisms of cell death in Alzheimer's disease, The Eighth Asia Pacific Multidisciplinary Meeting for Nervous System Diseases, Jan. 7-8, 2011 Hong Kong. 2011, 23. |
| Chang R.C.C., Zhang Q., Hung H.L. and Ho Y.S., Molecular mechanisms of initiating autophagy by oligomeric beta-amyloid peptide., The Croucher Foundation Conference, Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insightes. 2011, 19. |
| Chang R.C.C., Molecular mechanisms of initiating autophagy by oligomerix beta-amyloid peptide, Croucher Foundation Conference: Alzheimer's Disease Conference 2011: From Public Health, Basic and Clinical Sciences to Therapeutic Insights, Hong Kong. 2011. |
| Chang R.C.C., Our experience of Anti-aging Chinese Medicine Research to prevent aging-associated neurodegeneration, The 2nd International Society of Chinese Medicine”, The University of Macau, MACAU. 2010. |
| Chang R.C.C., Ho Y.S., Chiu K. and So K.F., Our experience of anti-Chinese medicine research to prevent aging-associated neurodegeneration. , The 2nd Macao Forum on Chinese Medical Sciences, Nov. 8-11, 2010 Macau. 2010. |
| Chang R.C.C., Zhang Q., Hung H.L. and Cheung Y.T., Perturbation of endoplasmic reticulum and mitochondria rather than reduced activity of mTOR trigger autophagy in neurons exposed to low molecular weight beta-amyloid peptide, Society for Neuroscience 2010, San Diego, USA. 2010, 247.14/H60. |
| Chang R.C.C., Risk factors for getting Alzheimer’s disease: from understanding the biological mechanisms to preventive opportunity, Biomedicine Strategic Research Theme Forum, LKS Faculty of Medicine, The University of Hong Kong. 2011. |
| Chang R.C.C., Scientific Advisory Committee, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, Spain. 2011. |
| Chang R.C.C., Scientific Advisory Committee, The 11th International Conference on Alzheimer's & Parkinson's Diseases, Florence, Italy (from 2011 to 2013). 2011. |
| Chang R.C.C., Session Chairman, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, Spain. 2011. |
| Chang R.C.C., Session Chairman, The 10th International Symposium on Alzheimer's & Parkinson's diseases. 2011. |
| Chang R.C.C., Session Chairman, The 6th International Symposium on Healthy Aging. 2011. |
| Chang R.C.C., Signaling Mechanism from Endoplasmic Reticulum Collapse to Induction of Autophagy in Neurons Stressed with Low Molecular Weight Beta-amyloid Peptides, The 10th International Conference on Alzheimer’s & Parkinson’s Diseases, Barcelona, SPAIN. 2011. |
| Chang R.C.C., Zhang Q., Hung H.L., Ho Y.S. and Wuwongse S., Signaling mechanism from endoplasmic reticulum collapse to induction of autophagy in neurons stressed with low molecular weight beta-amyloid peptides, The 10th International Conference on Alzheimer's & Parkinson's Disease, Barcelona, March 9-13, 2011. Abstract 350. |
| Chang R.C.C., Hung H.L., Wuwongse S., Zhang Q. and Ho Y.S., Stress responses of mitochondria to beta-amyloid peptide in Alzheimer's disease: do we understand the biological mechanisms now?, Croucher Advanced Study Institutes in Stress Responses of Mitochondria in Diabetes and Aging.. 2011. |
| Chang R.C.C., Stress responses of mitochondria to beta-amyloid peptide in Alzheimer’s disease: do we understand the biological mechanisms now?, Croucher Advanced Study Institutes on Mitochondrial Stress in Diabetes and Aging”, Hong Kong. 2011. |
| Chang R.C.C., The Open Enzyme Inhibition Journal. 2010, 1. |
| Chang R.C.C., What are the rationales of our decision-making in differentiating SH-SY5Y neuroblastoma cells in neurotoxicity research?, "Pitfalls of Cell-based Screening Assays - Is It the Cell, the Assay or the Question Asked?" Satellite Symposium for The Society for Neuroscience 2010, San Diego, USA. 2010. |
| Chang R.C.C. and Ho Y.S., What are the rationales of our decision-making in differentiating SH-SY5Y neuroblastoma cells in neurotoxicity research?, Satellite Meeting for Society for Neuroscience 2010, San Diego, USA. 2010. |
| Chiu K., So K.F. and Chang R.C.C., Immune modulation in glaucoma – can manipulation of microglia activation help?, Glaucoma / Book 2. University Campus STeP Ri, InTech, 2011. |
| Chiu K., Liang Y., Chang R.C.C. and So K.F., Lycium barbarum L.: a neuroprotective drug for glaucoma, 枸杞子–青光眼的神经保护剂, Ophthalmol CHN. 眼科, BeiJing CHN, 2011, 20(1): 21-27. |
| Chiu K., Leung I.Y.P., Lui J.C.H., Lok C.K.M., Ho Y.S., Baum L., So K.F. and Chang R.C.C., Morphometric analysis of inner retinal layer in a mouse model of Alzheimer’s disease. , Society for Neuroscience . 2010, 457.17/L9. |
| Chiu K., Chan T.F., Wu A., Leung I.Y.P., So K.F. and Chang R.C.C., Neurodegeneration of the retina in mouse models of Alzheimer’s disease: What can we learn from the retina?, Age. Springer, 2011. |
| Chiu K., Yeung S.C., Lok C.K.M., Zhou Y., Chang R.C.C. and So K.F., Neuroimmune responses of polysacharides from lycium barbarum (wolfberry) in retina after experimental glaucoma, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010 Hong Kong. 2010, 102 No.121. |
| Chiu K., Chan T.F., So K.F. and Chang R.C.C., Retinal neurodegeneration in AD transgenic mice, 从AD动物模型研究 视网膜神经细胞退化 , Joint seminar College of life sciences ShenZhen University/ HKU. 2011. |
| Chiu K., Lok C.K.M., Chang R.C.C. and So K.F., Wolfberry polysaccharide stimulates anti-stress capacity in retina against glaucoma. , Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 48 OP7. |
| Ho Y.S., So K.F. and Chang R.C.C., Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia, Chinese Medicine. 2011, 6: 1-6. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17. |
| Ho Y.S., Chao J., So K.F. and Chang R.C.C., The holistic approach of anti-aging lycium barbarum (wolfberry) in the protection against pathological factors related to Alzheimer's disease, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010, Hong Kong. 2010, 102 No. 120. |
| Hung C.H.L., Cheung Y.T., Wuwongse S., Zhang Q. and Chang R.C.C., Relationship between low molecular weight beta-amyloid peptide-induced fission/fusion imbalance and mitochondrial functions, Society for Neuroscience 2010, San Diego, USA. 2010, 247.15/H61. |
| Hung H.L., Cheung Y.T., Wuwongse S., Zhang Q., Ho Y.S. and Chang R.C.C., Mitochondria in Alzheimer's Disease: Relationship between morphology and functions, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P27. |
| Lau C.F., Ho Y.S., Poon C.H., Wuwongse S. and Chang R.C.C., Synaptic neuroprotective effect of testosterone in beta-amyloid-treated rat hippocampal neurons, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 57 P12. |
| Lau W.M., Lee C.D., Yau S.Y., Chang R.C.C. and So K.F., Facilitation of male sexual behavior by lycium barbarum (wolfberry) polysaccharide, The Consortium for Globalizaiton of Chinese Medicine. Aug. 23-25, 2010 Hong Kong. 2010, 106 No. 126. |
| Lau W.M., Ren C., Yang J., Yan S.W.L., Chang R.C.C., Pu M. and So K.F., Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal Mongolian gerbil (Meriones unguiculatus), Cell Transplantation. 2011, 20: 871-881. |
| Li S.Y., Yang D., Yeung C.M., Yu W.Y., Chang R.C.C., So K.F., Wong D.S.H. and Lo A.C.Y., Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury, PLoS One. 2011, 6(1): e16380. |
| Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54. |
| So K.F. and Chang R.C.C., Ginseng, Wolfberry, Bilberry in “Section 8: Non-pharmaceutical Medications and Approaches”, In: R.N. Weinreb & J. Liebmann , Medical Treatment of Glaucoma: World Glaucoma Association Consensus Series 7. Kugler Publication, 2010, 321-328. |
| So K.F. and Chang R.C.C., Molecular basis of neuroprotection in neurodegenerative diseases using Gouqizi (Wolfberry), The 4th Pan Pacific Symposium on Stem Cells and Cancer Researches, April 15-18, 2011 Taiwan.. 2011. |
| So K.F. and Chang R.C.C., Molecular mechanism of neuroprotection in neurodegenerative diseases using Gouqizi (Wolfberry), The 5th Beijing International Forum on Rehabilitation, Oct. 29 - Nov. 1, 2010, Beijing, China. 2010, 33-34. |
| So K.F. and Chang R.C.C., Neuroprotection in glaucoma using Gouqizi (Wolfberry), 首都醫科大學眼科學院２０１０年學朮年会. 2010, 15. |
| Suen K.C., Chan W.K. and Chang R.C.C., Development of a school-based neuroscience curriculum in a high school in Hong Kong, Society for Neuroscience 2010, San Diego, USA. 2010, 23.5/NNN44. |
| Suen K.C., Wong Y.H., Yuen C.T., Lam N.H., Ho H.Y., Lau Y.T., Cheng C.K., Lam H.C., Tam D.H.F., Lau S.P. and Chang R.C.C., Elicitation of a pungent sensation does not implicate memory modulation in adolescents aged 14-16, Society for Neuroscience 2010, San Diego, USA. 2010, 701.12/KKK33. |
| Wong G.T.H., Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone on cytoskeleton in dendrites and dendritic spines, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 67 P49. |
| Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Amyloid beta and corticosterone-mediated synaptic dysfunction, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 66 P46. |
| Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Chang R.C.C. and Law A.C.K., Neuroprotective role of antidepressants in amyloid and corticosterone-mediated synaptic dysfunction., The Croucher Foundation Conference: Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insights.. 2011, 29. |
| Wuwongse S., Hung H.L., Chang R.C.C. and Law A.C.K., The involvement of synaptic degeneration in major depressive disorder and antidepressant mechanisms of action., Society for Neuroscience 2010, San Diego, USA. 2010, 162.1/V9. |
| Wuwongse S., Chang R.C.C. and Law A.C.K., The putative neurodegenerative links between depression and Alzheimer's disease, Progress in Neurobiology. 2010, 91: 362-375. |
| Yang D., Yeung C.M., Li S.Y., Chang R.C.C., So K.F., Wong D.S.H. and Lo A.C.Y., Lycium barbarum polysaccharides protect brain from cerebral edema and blood-brain barrier disruption after ischemia/reperfusion injury, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 56 P6. |
| Zhang E., Yau S.Y., Lau W.M., Lee T.M.C., Chang R.C.C. and So K.F., Promotion of neurogenesis and preservation of dendrites by wolfberry in experimental depression, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 208. |
| Zhang Q., Hung H.L., Ho Y.S., Wuwongse S. and Chang R.C.C., Aggregation of the endoplasmic reticulum triggered by oligomeric Ab could facilitate formation of autophagosomes, Sixth International Symposium on Healthy Aging, March 5-6, 2011 Hong Kong. 2011, 47. |
| Zhang Q., Cheung Y.T., Ho Y.S. and Chang R.C.C., Low molecular weight Abeta induces autophagosome accumulation via endoplasmic reticulum aggregation, Society for Neuroscience 2010, San Diego, USA. 2010, 247.2/H48. |
| Researcher : Chao J |
| List of Research Outputs |
| Zheng Z., Ma J., Cheng K.W., Chao J., Zhu Q., Zhao M., Lin Z.X. and Wang M., Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas xomosus (L.) Merr.] fruit, Phytochemistry. 2010, 71: 2046-2051. |
| Researcher : Chau RMW |
| Project Title: | HUGO's Seventh International Human Genome Meeting, HGM2002 The Possible Mechanism of Action for Quinacrine Interacting the Scrapie Protein in Prion Disease |
| Investigator(s): | Chau RMW |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 04/2002 |
| Researcher : Chen AYS |
| Project Title: | Study of the role of polyol pathway activation the impaired nerve regeneration in diabetes |
| Investigator(s): | Chen AYS, Chung SK |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2008 |
| Researcher : Cheng L |
| List of Research Outputs |
| Cheng L., Yeung P.K.K., Kai A.K.L., Chung S.S.M. and Chung S.K., Role of Epac in the pathogenesis of ischemic stroke, 15th Research Postgraduate Symposium, Dec. 1-2, 2010, The University of Hong Kong, Hong Kong. 2010, 82. |
| Researcher : Cheung A |
| Project Title: | Targeting NFKB pathway suppresses human esophageal cancer progression |
| Investigator(s): | Cheung A |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Completion Date: | 12/2010 |
| Project Title: | Synergistic effect and molecular mechanisms of green tea (EGCG) and vitamin C in the prevention of esophageal cancer |
| Investigator(s): | Cheung A, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2010 |
| Project Title: | Role of Id1-induced IGF2 in autocrine/endocrine promotion of esophageal cancer tumorigenesis and metastasis implications for targeted therapy |
| Investigator(s): | Cheung A, Chan KW, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | Impact of replication fork stalling on centromeric instability |
| Investigator(s): | Cheung A, Deng W, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| Project Title: | 2nd International on Cancer Immunotherapy & Immunomonitoring Conference IGF1R-targeting as potential immunotherapy for esophageal cancer |
| Investigator(s): | Cheung A |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Cheung A., Applied Immunohistochemistry & Molecular Morphology, Editorial Board, Lippincott Williams & Wilkins, 2011. |
| Cheung A., Li B., Chan K.W. and Tsao G.S.W., IGF1R-targeting as potential immunotherapy for esophageal cancer, 2nd International Cancer Immunotherapy and Immujomonitoring Conference, May 2-5, Budapest, Hungary. 2011, 70. |
| Cheung A., Role of Id1 in esophageal cancer, Advanced Study Institute, Croucher Foundation, on “Molecular Genetics and Clinical Advances in the Study of Esophageal and Gastric Cancers”, January 23-27, 2011. 2011. |
| Cheung A., The Open Pathology Journal, Editorial Board, Bentham Open, 2011. |
| Cheung P.P.Y., Deng W., Man C.W.Y., Tse W.W., Srivastava G., Law S.Y.K., Tsao G.S.W. and Cheung A., Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: Implications for carcinogenesis, Cancer Letters. 2010, 293(1): 41-51. |
| Cheung P.Y., Yip Y.L., Tsao G.S.W., Ching Y.P. and Cheung A., Id-1 induces cell invasiveness in immortalized epithelial cells by regulating cadherin switching and Rho GTPases, Journal of Cellular Biochemistry. 2011, 112: 157-168. |
| Li J., Li B., Tsao G.S.W. and Cheung A., Role of AMPK-mTOR signaling in anticancer effects of silibinin on esophageal squamous cell carcinoma, Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, April 2-6, 2011 U.S.A.. 2011. |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Researcher : Cheung A. |
| Project Title: | Targeting NFKB pathway suppresses human esophageal cancer progression |
| Investigator(s): | Cheung A |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Completion Date: | 12/2010 |
| Project Title: | Synergistic effect and molecular mechanisms of green tea (EGCG) and vitamin C in the prevention of esophageal cancer |
| Investigator(s): | Cheung A, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2010 |
| Project Title: | Role of Id1-induced IGF2 in autocrine/endocrine promotion of esophageal cancer tumorigenesis and metastasis implications for targeted therapy |
| Investigator(s): | Cheung A, Chan KW, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | Impact of replication fork stalling on centromeric instability |
| Investigator(s): | Cheung A, Deng W, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| Project Title: | 2nd International on Cancer Immunotherapy & Immunomonitoring Conference IGF1R-targeting as potential immunotherapy for esophageal cancer |
| Investigator(s): | Cheung A |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Deng W..., Tsao G...S...W..., Mak W...Y...G..., Tsang C...M..., Ching Y...P..., Guan X..., Huen M...S...Y... and Cheung A..., Impact of G2 checkpoint defect on centromeric instability, Oncogene. 2011, 30: 1281-1289. |
| Researcher : Cheung ALM |
| Project Title: | Targeting NFKB pathway suppresses human esophageal cancer progression |
| Investigator(s): | Cheung A |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Completion Date: | 12/2010 |
| Project Title: | Synergistic effect and molecular mechanisms of green tea (EGCG) and vitamin C in the prevention of esophageal cancer |
| Investigator(s): | Cheung A, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2010 |
| Project Title: | Role of Id1-induced IGF2 in autocrine/endocrine promotion of esophageal cancer tumorigenesis and metastasis implications for targeted therapy |
| Investigator(s): | Cheung A, Chan KW, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | Impact of replication fork stalling on centromeric instability |
| Investigator(s): | Cheung A, Deng W, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| Project Title: | 2nd International on Cancer Immunotherapy & Immunomonitoring Conference IGF1R-targeting as potential immunotherapy for esophageal cancer |
| Investigator(s): | Cheung A |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Researcher : Cheung MPL |
| List of Research Outputs |
| Zhao W., Fung Y.S., Waisum O. and Cheung M.P.L., L-Cysteine-capped CdTe Quantum Dots as a Fluorescence Probe for Determination of Cardiolipin , Analytical Sciences. 2010, 26: 879-884. |
| Researcher : Cheung PPY |
| List of Research Outputs |
| Cheung P.P.Y., Deng W., Man C.W.Y., Tse W.W., Srivastava G., Law S.Y.K., Tsao G.S.W. and Cheung A., Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: Implications for carcinogenesis, Cancer Letters. 2010, 293(1): 41-51. |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Researcher : Cheung PY |
| List of Research Outputs |
| Cheung P.Y., Yip Y.L., Tsao G.S.W., Ching Y.P. and Cheung A., Id-1 induces cell invasiveness in immortalized epithelial cells by regulating cadherin switching and Rho GTPases, Journal of Cellular Biochemistry. 2011, 112: 157-168. |
| Researcher : Cheung Y.T. |
| List of Research Outputs |
| Cheung Y...T..., Zhang Q., Hung H.L., Lai S...W..., Yu M...S..., So K...F... and Chang R...C...C..., Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight b-amyloid peptide, Journal of Cellular and Molecular Medicine. 2011, 15(2): 244-257. |
| Researcher : Cheung YH |
| List of Research Outputs |
| Cheung Y.H., Lo A.C.Y., Wong D.S.H. and Lai W.W.K., Lectin from Agaricus bisporus suppressed Akt phosphorylation and arrested cell cycle progression for retinal pigment epithelial cells, ARVO 2011 Annual Meeting. 2011. |
| Researcher : Cheung YT |
| List of Research Outputs |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime MTOR suppression in low molecular weight Ab induced autophagy, Alzheimer's & Dementia. 2010, 6(4) Supplement: S243. |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime mTOR suppression in low molecular weight Abeta induced autophagy, Alzheimer's and Dementia (Suppl. 1). 2010, S243. |
| Chang R.C.C., Zhang Q., Hung H.L. and Cheung Y.T., Perturbation of endoplasmic reticulum and mitochondria rather than reduced activity of mTOR trigger autophagy in neurons exposed to low molecular weight beta-amyloid peptide, Society for Neuroscience 2010, San Diego, USA. 2010, 247.14/H60. |
| Hung C.H.L., Cheung Y.T., Wuwongse S., Zhang Q. and Chang R.C.C., Relationship between low molecular weight beta-amyloid peptide-induced fission/fusion imbalance and mitochondrial functions, Society for Neuroscience 2010, San Diego, USA. 2010, 247.15/H61. |
| Hung H.L., Cheung Y.T., Wuwongse S., Zhang Q., Ho Y.S. and Chang R.C.C., Mitochondria in Alzheimer's Disease: Relationship between morphology and functions, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P27. |
| Zhang Q., Cheung Y.T., Ho Y.S. and Chang R.C.C., Low molecular weight Abeta induces autophagosome accumulation via endoplasmic reticulum aggregation, Society for Neuroscience 2010, San Diego, USA. 2010, 247.2/H48. |
| Researcher : Ching Y.P. |
| Project Title: | Roles of p21-activated protein kinase (Pak) 1 in the pathogenesis of liver cancer |
| Investigator(s): | Ching YP, Ng IOL, Jin D, Yau TO |
| Department: | Pathology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2006 |
| Project Title: | The roles of CDK5 activator binding protein, LZAP, in the pathogenesis of neurodegenerative disease |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | Travel Grants for NSFC/RGC JRS |
| Start Date: | 12/2007 |
| Project Title: | Functional characterization of a putative tumour suppressor, AMP-activated protein kinase, in liver cancer |
| Investigator(s): | Ching YP, Jin D, Ng IOL |
| Department: | Pathology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2008 |
| Project Title: | The roles of CDK5 activator binding protein, LZAP, in the pathogenesis of neurodegenerative disease |
| Investigator(s): | Ching YP, Jin D |
| Department: | Anatomy |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2009 |
| Project Title: | Characterisation of the role of p21-activated protein kinase 4 in liver cancer |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2009 |
| Completion Date: | 03/2011 |
| Project Title: | Hepatitis B virus promotes hepatocarcinogenesis by activation of Pak1 |
| Investigator(s): | Ching YP, Jin D |
| Department: | Anatomy |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 01/2010 |
| Project Title: | Functional characterisation of a novel centrosomal protein, TAX1BP2, in liver cancer development |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Characterisation of the roles of LKB1 in liver cancer formation |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2010 |
| Project Title: | BIT's 1st World Congress of Virus and Infections 2010 The role of HBx oncoprotein in HCC metastasis |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 07/2010 |
| Completion Date: | 08/2010 |
| Project Title: | A study of the roles of an atypical small Rho GTPase, RhoV, in liver cancer |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Deng W..., Tsao G...S...W..., Mak W...Y...G..., Tsang C...M..., Ching Y...P..., Guan X..., Huen M...S...Y... and Cheung A..., Impact of G2 checkpoint defect on centromeric instability, Oncogene. 2011, 30: 1281-1289. |
| Researcher : Ching YP |
| Project Title: | Roles of p21-activated protein kinase (Pak) 1 in the pathogenesis of liver cancer |
| Investigator(s): | Ching YP, Ng IOL, Jin D, Yau TO |
| Department: | Pathology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2006 |
| Project Title: | The roles of CDK5 activator binding protein, LZAP, in the pathogenesis of neurodegenerative disease |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | Travel Grants for NSFC/RGC JRS |
| Start Date: | 12/2007 |
| Project Title: | Functional characterization of a putative tumour suppressor, AMP-activated protein kinase, in liver cancer |
| Investigator(s): | Ching YP, Jin D, Ng IOL |
| Department: | Pathology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2008 |
| Project Title: | The roles of CDK5 activator binding protein, LZAP, in the pathogenesis of neurodegenerative disease |
| Investigator(s): | Ching YP, Jin D |
| Department: | Anatomy |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2009 |
| Project Title: | Characterisation of the role of p21-activated protein kinase 4 in liver cancer |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2009 |
| Completion Date: | 03/2011 |
| Project Title: | Hepatitis B virus promotes hepatocarcinogenesis by activation of Pak1 |
| Investigator(s): | Ching YP, Jin D |
| Department: | Anatomy |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 01/2010 |
| Project Title: | Functional characterisation of a novel centrosomal protein, TAX1BP2, in liver cancer development |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Characterisation of the roles of LKB1 in liver cancer formation |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2010 |
| Project Title: | BIT's 1st World Congress of Virus and Infections 2010 The role of HBx oncoprotein in HCC metastasis |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 07/2010 |
| Completion Date: | 08/2010 |
| Project Title: | A study of the roles of an atypical small Rho GTPase, RhoV, in liver cancer |
| Investigator(s): | Ching YP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Chan M.L., Xu H. and Ching Y.P., Characterization of PAK4 and RhoV in hepatocellular carcinoma (HCC)., In: European Molecular Biology Organization, The EMBO Meeting 2010 Barcelona Spain . 2010. |
| Cheung P.Y., Yip Y.L., Tsao G.S.W., Ching Y.P. and Cheung A., Id-1 induces cell invasiveness in immortalized epithelial cells by regulating cadherin switching and Rho GTPases, Journal of Cellular Biochemistry. 2011, 112: 157-168. |
| Ching Y.P., Academic Editor , In: PLoS ONE and the Community Journals, PLOS One. 2010. |
| Ching Y.P., Academic Editor, World Journal of Clinical Oncology . 2010. |
| Ching Y.P., Role of Cdk5 signaling in neurodegenerative disease, In: Alzheimer’s Disease Research Network, SRT Healthy Aging, & Research Centre of Heart, Brain, Hormone and Healthy Aging, The University of Hong Kong , Croucher Foundation Conference: Alzheimer’s Disease Conference 2011: From Public Health, Basic and Clinical Sciences to Therapeutic Insights. 2011. |
| Ching Y.P., The role of HBx oncoprotein in HCC metastasis, BIT's 1st World Congress of Virus and Infections 2010. 2010. |
| Huen M.S.Y., Sy S.M.H., Leung K.M., Ching Y.P., Tipoe G.L., Man C., Dong S. and Chen J., SON is a spliceosome-associated factor required for mitotic progression, CELL CYCLE. 2010, 9(13): 2679-2685. |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Effect of corticosterone and paroxetine on masculine mating behavior: Possible involvement of neurogenesis, The Journal of Sexual Medicine. 2011, 8: 1390-1403. |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Possible involvement of neurogenesis in male rat mating behavior, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 141. |
| Luk S.U. and Ching Y.P., Hepatitis B virus promotes hepatocarcinogenesis by activation of Pak1, In: Hong Kong Government , Health Research Symposium 2010: Improving health and recognising excellence . 2010. |
| Mak W.Y.G., Chan M.L., Leong V.Y.L., Lee M.F., Yau T.O., Ng I.O.L. and Ching Y.P., Overexpression of a novel activator of PAK4, the CDK5 kinase-associated protein CDK5RAP3, promotes hepatocellular carcinoma metastasis, Cancer Research. 2011, 71: 2949-58. |
| Tao K.P., Fong S.W., Lu Z., Ching Y.P., Chan K.W. and Chan S.Y., TSPYL2 is important for G1 checkpoint maintenance upon DNA damage, PLoS One. 2011, 6(6): e21602. |
| Wang N., Feng Y., Lau E.P.W., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W.W. and Tsao G.S.W., F-actin reorganization and inactivation of Rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration, Integrative Cancer Therapies. USA, SAGE, 2010. |
| Researcher : Chiu J |
| List of Research Outputs |
| Cai Z., Wang Q., Zhou Y., Zheng L., Chiu J. and He Q.Y., Epidermal growth factor-induced epithelial-mesenchymal transiotion in human esophageal carcinoma cells --a model for the study of metastasis, Cancer Letters. 2010, 296(1): 88-95. |
| Lau A.T., Xu Y.M. and Chiu J., Proteomic analysis of human pluripotent cells, In: Borowski, M., Luong, M.X., Shi, M.J., Smith, K.P., Stein, G. S., Vazquez, P., Human Stem Cell Technology and Biology: A Research Guide and Laboratory Manual. Wiley-Blackwell Publishers, 2011, Chapter 21. |
| Li G., Lee L.S., Li M., Tsao G.S.W. and Chiu J., Molecular changes during arsenic-induced cell transformation, Journal of Cellular Physiology. 2011, in press. |
| Researcher : Chiu K |
| Project Title: | Significance of amyloid precursor protein processing and amyloid beta deposition in the retinal neurodegeneration: do ER-stress signaling or mitochondrial stress signaling involved? |
| Investigator(s): | Chiu K, So KF, Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2009 |
| List of Research Outputs |
| Chan T.F., Chiu K., Lok C.K.M., Lok C.K.M., Ho Y.S., So K.F. and Chang R.C.C., Loss of neurons in the inner retinal neuron of transgenic mice bearing human mutated amyloid precursor protein., Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P25. |
| Chang R.C.C., Ho Y.S., Chiu K. and So K.F., Our experience of anti-Chinese medicine research to prevent aging-associated neurodegeneration. , The 2nd Macao Forum on Chinese Medical Sciences, Nov. 8-11, 2010 Macau. 2010. |
| Chiu K., So K.F. and Chang R.C.C., Immune modulation in glaucoma – can manipulation of microglia activation help?, Glaucoma / Book 2. University Campus STeP Ri, InTech, 2011. |
| Chiu K., Liang Y., Chang R.C.C. and So K.F., Lycium barbarum L.: a neuroprotective drug for glaucoma, 枸杞子–青光眼的神经保护剂, Ophthalmol CHN. 眼科, BeiJing CHN, 2011, 20(1): 21-27. |
| Chiu K., Leung I.Y.P., Lui J.C.H., Lok C.K.M., Ho Y.S., Baum L., So K.F. and Chang R.C.C., Morphometric analysis of inner retinal layer in a mouse model of Alzheimer’s disease. , Society for Neuroscience . 2010, 457.17/L9. |
| Chiu K., Chan T.F., Wu A., Leung I.Y.P., So K.F. and Chang R.C.C., Neurodegeneration of the retina in mouse models of Alzheimer’s disease: What can we learn from the retina?, Age. Springer, 2011. |
| Chiu K., Yeung S.C., Lok C.K.M., Zhou Y., Chang R.C.C. and So K.F., Neuroimmune responses of polysacharides from lycium barbarum (wolfberry) in retina after experimental glaucoma, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010 Hong Kong. 2010, 102 No.121. |
| Chiu K., Chan T.F., So K.F. and Chang R.C.C., Retinal neurodegeneration in AD transgenic mice, 从AD动物模型研究 视网膜神经细胞退化 , Joint seminar College of life sciences ShenZhen University/ HKU. 2011. |
| Chiu K., Lok C.K.M., Chang R.C.C. and So K.F., Wolfberry polysaccharide stimulates anti-stress capacity in retina against glaucoma. , Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 48 OP7. |
| Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54. |
| Researcher : Chiu YT |
| List of Research Outputs |
| Chiu Y.T., Studying the role of androgen receptor signaling in the development, progression and therapeutic approach of prostate cancer. 2010, 175 pages. |
| Chua C.W., Chiu Y.T., Yuen H.F., Chan K.W., Wang X., Ling M.T. and Wong Y.C., Differential expression of MSX2 in nodular hyperplasia, high-grade prostatic intraepithelial neoplasia and prostate adenocarcinoma, APMIS. 2010, 118(12): 918-26. |
| Luk S.U., Lee K.W., Liu J.I., Lee D.T.W., Chiu Y.T., Ma S.K.Y., Ng I.O.L., Wong Y.C., Chan F.L. and Ling M.T., Chemopreventive effect of PSP through targeting of prostate cancer stem cell-like population, PLoS One. 2011, 6: e19804. |
| Researcher : Chu TH |
| Project Title: | Effects of trophic factor on Schwann cell migration for spinal root avulsion injury repair |
| Investigator(s): | Chu TH, Wu W |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2009 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Yuan Q.J., Hu B., Chu T.H., Su H., Zhang W., So K.F., Lin Z. and Wu W., Co-expression of GAP-43 and nNOS in avulsed motoneurons and their potential role for motoneuron regeneration, Nitric Oxide. 2010, 23: 258-263. |
| Researcher : Chua CW |
| List of Research Outputs |
| Chua C.W., Chiu Y.T., Yuen H.F., Chan K.W., Wang X., Ling M.T. and Wong Y.C., Differential expression of MSX2 in nodular hyperplasia, high-grade prostatic intraepithelial neoplasia and prostate adenocarcinoma, APMIS. 2010, 118(12): 918-26. |
| Researcher : Chung SK |
| Project Title: | Role of Epac1, cAMP-regulated guanine nucleotide exchange factor 1, in blood brain barrier maintenance, infarct and neurological deficits during ischemia/reperfusion injury |
| Investigator(s): | Chung SK |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | Start Domain-Containing Protein 13, STARD13, RhoA GTPase-activating protein in painful neuropathy: common and debilitating complication of diabetes. |
| Investigator(s): | Chung SK |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2010 |
| Completion Date: | 03/2011 |
| Project Title: | Role of transcription factor NFAT5 target gene aldose reductase in inflammation, edema and oxidative stress after spinal cord injury |
| Investigator(s): | Chung SK |
| Department: | Anatomy |
| Source(s) of Funding: | Travel Grants for NSFC/RGC JRS |
| Start Date: | 12/2010 |
| Project Title: | Role of STARD13, Rho GTPase activating protein, in blood-brain barrier maintenance, infarct and dementia associated with brain injury |
| Investigator(s): | Chung SK |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2011 |
| List of Research Outputs |
| Chen C., Zhang X., Wong L.C., Chung S.K., Xu A. and Lam K.S.L., Adipose Tissue-specific Suppression Of C-jun Terminal Kinase Attenuates Obesity-related Metabolic Disorders In A Genetic Mouse Model Of Obesity And Type 2 Diabetes, ADA 2011. |
| Cheng L., Yeung P.K.K., Kai A.K.L., Chung S.S.M. and Chung S.K., Role of Epac in the pathogenesis of ischemic stroke, 15th Research Postgraduate Symposium, Dec. 1-2, 2010, The University of Hong Kong, Hong Kong. 2010, 82. |
| Dai Z., Chung S.K., Miao D., Lau K.S., Chan A.W.H. and Kung A.W.C., Sodium/myo-inositol cotransporter 1 and myo-inositol are essential for osteogenesis and bone formation, Journal of Bone and Mineral Research. 2011, 26(3): 582-590. |
| Durairajan S.S.K., Liu L.F., Lu J.H., Koo I., Maruyama K., Chung S.K., Huang J. and Li M., Stimulation of non-amyloidogenic processing of amyloid-b protein precursor by cryptotanshinone involves activation and translocation of ADAM10 and PKC-a, Journal of Alzheimer's Disease. 2011, 25: 245-262. |
| Liu J., Chung S.S.M. and Chung S.K., Role of Epac1 in pathogenesis of diabetic retinopathy, 15th Research Postgraduate Symposium, Dec. 1-2, 2010, The University of Hong Kong, Hong Kong. 2010, 87. |
| Lo A.C.Y., Fu Z., Li S.Y., Wong D.S.H. and Chung S.K., Aldose reductase deficiency reduces retinal injury in the mouse oxygen-induced retinopathy model, ARVO 2011 Annual Meeting. 2011. |
| Wong A.S.L., Lee R.H.K., Cheung A.Y., Yeung P.K.K., Chung S.K., Cheung Z.H. and Ip N.Y., Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease, Nature cell Biology. 2011, 13(5): 568-579. |
| Yeung P.K.K., Lai K.W., Son H.J., Zhang X., Hwang O., Chung S.S.M. and Chung S.K., Aldose reductase-deficiency leads to more significant loss of dopaminergeric neurons with incresed levels of dopamine, tetrahydrobiopterin and free radical accumulation under experimental Parkinson's Disease condition, Society for Neuroscience 2010. |
| Yu J.L., Chung S.K. and Chan G.C.F., Epac regulates human mesenchymal stem cells homing., 15th Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, Dec 1 & 2, 2010 . 2010. |
| Zhang X., Lam K.S.L., Ye H., Chung S.K., Zhou M., Wang Y. and Xu A., Adipose tissue-specific inhibition of hypoxia-inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice, J Biol Chem. 2010, 285: 32869-77. |
| Zhang X., Chung S.S.M. and Chung S.K., Hypertensive mice with over-expression of endothelin-1 show hyperactivity, impaired sensorimotor gating, mild congnitive deficit and cerebral vascular oxidative stress, FENS Abstracts. 2010, 5: 204.9. |
| Zhang X., Xu A., Chung S.K., Cresser J.H., Sweeney G., Wong L.C., Lin A. and Lam K.S.L., Selective inactivation of c-Jun NH2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in mice, Diabetes . 2011, 60: 486-95. |
| Researcher : Deng W |
| List of Research Outputs |
| Chen M.H., Huang J., Deng H.K., Dong S., Deng W., Tsang S.L., Huen M.S.Y., Chen L., Zan T., Zhu G. and Guan X., Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability. , BMC Cancer . 2011, 11: 199. |
| Cheung P.P.Y., Deng W., Man C.W.Y., Tse W.W., Srivastava G., Law S.Y.K., Tsao G.S.W. and Cheung A., Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: Implications for carcinogenesis, Cancer Letters. 2010, 293(1): 41-51. |
| Li Y., Nie C.J., Hu L., Qin Y., Liu H.B., Zeng T.T., Chen L., Fu L., Deng W., Chen S.P., Jia W.H., Zhang C., Xie D. and Guan X.Y., Characterization of a novel mechanism of genomic instability involving SEI1/SET/NM23H1 pathway in esophageal cancers. , Cancer Research. 2010, 70: 5695-5705. |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Researcher : Deng W. |
| List of Research Outputs |
| Deng W..., Tsao G...S...W..., Mak W...Y...G..., Tsang C...M..., Ching Y...P..., Guan X..., Huen M...S...Y... and Cheung A..., Impact of G2 checkpoint defect on centromeric instability, Oncogene. 2011, 30: 1281-1289. |
| Researcher : Dong S |
| List of Research Outputs |
| Sy M.H., Jiang J., Dong S., Lok T.M., Wu J., Cai H., Yeung E.S., Huang J., Chen J., Deng Y. and Huen M.S.Y., Critical roles of Ring Finger Protein RNF8 in replication stress responses, Journal of Biological Chemistry. 2011, 286: 22355-22361. |
| Researcher : Du Y |
| List of Research Outputs |
| Du Y., Xiao Q. and Yip H.K.F., Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the Smad/Id cascade, Investigative Ophthalmology and Visual Science. Association for Research in Vision and Ophthalmology, 2010, 51: 3764-3773. |
| Du Y. and Yip H.K.F., The expression of roles of inhibitor of DNA binding helix-loop-helix proteins in the developing and adult mouse retina. , Neuroscience. Elsevier, 2011, 175: 367-379. |
| Researcher : Du Y |
| List of Research Outputs |
| Du Y., Xiao Q. and Yip H.K.F., Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the Smad/Id cascade, Investigative Ophthalmology and Visual Science. Association for Research in Vision and Ophthalmology, 2010, 51: 3764-3773. |
| Du Y. and Yip H.K.F., The expression of roles of inhibitor of DNA binding helix-loop-helix proteins in the developing and adult mouse retina. , Neuroscience. Elsevier, 2011, 175: 367-379. |
| Researcher : Ellis-Behnke RG |
| Project Title: | The ADME of Self-assembling Nanomaterials |
| Investigator(s): | Ellis-Behnke RG |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2008 |
| Project Title: | Incorporation Dynamics of Additives and Self-assembly peptides (SAPs) at Nanoscale for Central Nervous System (CNS) Regeneration |
| Investigator(s): | Ellis-Behnke RG |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2009 |
| Project Title: | Self-assembling Peptides (SAPs) at Nanoscale for Blood Preservation |
| Investigator(s): | Ellis-Behnke RG |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 06/2009 |
| List of Research Outputs |
| Woo P.C.Y., Lau S.K.P., Lee P., Miao J., Fung A.M.Y., Choi K.Y., Ellis-Behnke R.G. and Yuen K.Y., Resequencing microarray for detection of human adenoviruses in patients with community-acquired gastroenteritis: a proof of concept study, Journal of Medical Microbiology. 2010, 59: 1387-1390. |
| Researcher : Fu Q |
| List of Research Outputs |
| Liao X.X., Chen D., Shi J., Sun Y.Q., Sun S.J., So K.F. and Fu Q., The expression patterns of Nogo-A, myelin associated glycoprotein and oligodendrocyte myelin glycoprotein in the retina after ocular hypertension, Neurochemistry Research. 2011, 36: 1955-1961. |
| Researcher : Fu Z |
| List of Research Outputs |
| Lo A.C.Y., Fu Z., Li S.Y., Wong D.S.H. and Chung S.K., Aldose reductase deficiency reduces retinal injury in the mouse oxygen-induced retinopathy model, ARVO 2011 Annual Meeting. 2011. |
| Researcher : Hau PM |
| List of Research Outputs |
| Hau P.M., Tsang C.M., Yip Y.L., Huen M.S.Y. and Tsao G.S.W., Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells, PLoS ONE. PLoS ONE, 2011. |
| Hau P.M., Regulation and function of LMP1 in epithelial cells. 2010, 172 pages. |
| Researcher : Hau PM |
| List of Research Outputs |
| Hau P.M., Tsang C.M., Yip Y.L., Huen M.S.Y. and Tsao G.S.W., Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells, PLoS ONE. PLoS ONE, 2011. |
| Hau P.M., Regulation and function of LMP1 in epithelial cells. 2010, 172 pages. |
| Researcher : Ho CT |
| List of Research Outputs |
| Ho C.T., A study of the effects of (-)-epigallocatechin-3-gallate (EGCG) on a clinically relevant rat model of non-alcoholic fatty liver disease (NAFLD). 2010, 154 pages. |
| Researcher : Ho YS |
| Project Title: | Investigating the potential of anti-inflammatory cytokine Interleukin-10 to attenuate synaptic degeneration in systemic inflammation-induced depression |
| Investigator(s): | Ho YS, Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2011 |
| Project Title: | The 10th International Conference on Alzheimer's and Parkinson's Diseases (AD/PD 2011) Endoplasmic reticulum stress induces tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease |
| Investigator(s): | Ho YS |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 03/2011 |
| Completion Date: | 03/2011 |
| List of Research Outputs |
| Chan T.F., Chiu K., Lok C.K.M., Lok C.K.M., Ho Y.S., So K.F. and Chang R.C.C., Loss of neurons in the inner retinal neuron of transgenic mice bearing human mutated amyloid precursor protein., Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P25. |
| Chang R.C.C., Zhang Q., Hung H.L., Wuwongse S. and Ho Y.S., Mechanisms of cell death in Alzheimer's disease, The Eighth Asia Pacific Multidisciplinary Meeting for Nervous System Diseases, Jan. 7-8, 2011 Hong Kong. 2011, 23. |
| Chang R.C.C., Zhang Q., Hung H.L. and Ho Y.S., Molecular mechanisms of initiating autophagy by oligomeric beta-amyloid peptide., The Croucher Foundation Conference, Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insightes. 2011, 19. |
| Chang R.C.C., Ho Y.S., Chiu K. and So K.F., Our experience of anti-Chinese medicine research to prevent aging-associated neurodegeneration. , The 2nd Macao Forum on Chinese Medical Sciences, Nov. 8-11, 2010 Macau. 2010. |
| Chang R.C.C., Zhang Q., Hung H.L., Ho Y.S. and Wuwongse S., Signaling mechanism from endoplasmic reticulum collapse to induction of autophagy in neurons stressed with low molecular weight beta-amyloid peptides, The 10th International Conference on Alzheimer's & Parkinson's Disease, Barcelona, March 9-13, 2011. Abstract 350. |
| Chang R.C.C., Hung H.L., Wuwongse S., Zhang Q. and Ho Y.S., Stress responses of mitochondria to beta-amyloid peptide in Alzheimer's disease: do we understand the biological mechanisms now?, Croucher Advanced Study Institutes in Stress Responses of Mitochondria in Diabetes and Aging.. 2011. |
| Chang R.C.C. and Ho Y.S., What are the rationales of our decision-making in differentiating SH-SY5Y neuroblastoma cells in neurotoxicity research?, Satellite Meeting for Society for Neuroscience 2010, San Diego, USA. 2010. |
| Chiu K., Leung I.Y.P., Lui J.C.H., Lok C.K.M., Ho Y.S., Baum L., So K.F. and Chang R.C.C., Morphometric analysis of inner retinal layer in a mouse model of Alzheimer’s disease. , Society for Neuroscience . 2010, 457.17/L9. |
| Ho Y.S., So K.F. and Chang R.C.C., Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia, Chinese Medicine. 2011, 6: 1-6. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17. |
| Ho Y.S., Chao J., So K.F. and Chang R.C.C., The holistic approach of anti-aging lycium barbarum (wolfberry) in the protection against pathological factors related to Alzheimer's disease, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010, Hong Kong. 2010, 102 No. 120. |
| Hung H.L., Cheung Y.T., Wuwongse S., Zhang Q., Ho Y.S. and Chang R.C.C., Mitochondria in Alzheimer's Disease: Relationship between morphology and functions, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P27. |
| Lau C.F., Ho Y.S., Poon C.H., Wuwongse S. and Chang R.C.C., Synaptic neuroprotective effect of testosterone in beta-amyloid-treated rat hippocampal neurons, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 57 P12. |
| Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54. |
| Wong G.T.H., Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone on cytoskeleton in dendrites and dendritic spines, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 67 P49. |
| Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Amyloid beta and corticosterone-mediated synaptic dysfunction, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 66 P46. |
| Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Chang R.C.C. and Law A.C.K., Neuroprotective role of antidepressants in amyloid and corticosterone-mediated synaptic dysfunction., The Croucher Foundation Conference: Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insights.. 2011, 29. |
| Zhang Q., Hung H.L., Ho Y.S., Wuwongse S. and Chang R.C.C., Aggregation of the endoplasmic reticulum triggered by oligomeric Ab could facilitate formation of autophagosomes, Sixth International Symposium on Healthy Aging, March 5-6, 2011 Hong Kong. 2011, 47. |
| Zhang Q., Cheung Y.T., Ho Y.S. and Chang R.C.C., Low molecular weight Abeta induces autophagosome accumulation via endoplasmic reticulum aggregation, Society for Neuroscience 2010, San Diego, USA. 2010, 247.2/H48. |
| Researcher : Hu B |
| List of Research Outputs |
| Yuan Q.J., Hu B., Chu T.H., Su H., Zhang W., So K.F., Lin Z. and Wu W., Co-expression of GAP-43 and nNOS in avulsed motoneurons and their potential role for motoneuron regeneration, Nitric Oxide. 2010, 23: 258-263. |
| Researcher : Huen M.S.Y. |
| Project Title: | Functional characterisation of EXPAND1 and its role in the maintenance of genome stability and tumor suppression. |
| Investigator(s): | Huen MSY |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 09/2009 |
| Completion Date: | 08/2010 |
| Project Title: | Monitoring DNA damage Using a Novel Fluorescence-based Biosensor: A platform for Drug Discovery and Genotoxic Evaluations |
| Investigator(s): | Huen MSY, Sy MH |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 09/2010 |
| Completion Date: | 08/2011 |
| Project Title: | Keystone Symposia on Molecular and Cellular Biology Meeting on Genomic Instability and DNA Repair Limiting histone ubiquitylation selectively promotes homologous recombination DNA repair |
| Investigator(s): | Huen MSY |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 01/2011 |
| Completion Date: | 02/2011 |
| Project Title: | Characterization of USP34, a novel ubiquitin specific peptidase involved in the DNA Damage Response |
| Investigator(s): | Huen MSY |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Deng W..., Tsao G...S...W..., Mak W...Y...G..., Tsang C...M..., Ching Y...P..., Guan X..., Huen M...S...Y... and Cheung A..., Impact of G2 checkpoint defect on centromeric instability, Oncogene. 2011, 30: 1281-1289. |
| Researcher : Huen MSY |
| Project Title: | Functional characterisation of EXPAND1 and its role in the maintenance of genome stability and tumor suppression. |
| Investigator(s): | Huen MSY |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 09/2009 |
| Completion Date: | 08/2010 |
| Project Title: | Monitoring DNA damage Using a Novel Fluorescence-based Biosensor: A platform for Drug Discovery and Genotoxic Evaluations |
| Investigator(s): | Huen MSY, Sy MH |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 09/2010 |
| Completion Date: | 08/2011 |
| Project Title: | Keystone Symposia on Molecular and Cellular Biology Meeting on Genomic Instability and DNA Repair Limiting histone ubiquitylation selectively promotes homologous recombination DNA repair |
| Investigator(s): | Huen MSY |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 01/2011 |
| Completion Date: | 02/2011 |
| Project Title: | Characterization of USP34, a novel ubiquitin specific peptidase involved in the DNA Damage Response |
| Investigator(s): | Huen MSY |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Chen M.H., Huang J., Deng H.K., Dong S., Deng W., Tsang S.L., Huen M.S.Y., Chen L., Zan T., Zhu G. and Guan X., Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability. , BMC Cancer . 2011, 11: 199. |
| Hau P.M., Tsang C.M., Yip Y.L., Huen M.S.Y. and Tsao G.S.W., Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells, PLoS ONE. PLoS ONE, 2011. |
| Huen M.S.Y., Sy S.M.H., Leung K.M., Ching Y.P., Tipoe G.L., Man C., Dong S. and Chen J., SON is a spliceosome-associated factor required for mitotic progression, CELL CYCLE. 2010, 9(13): 2679-2685. |
| Huen M.S.Y., Understanding the Mammalian DNA Damage Response, 17th Hong Kong International Cancer Congress.. 2010, N/A. |
| Sy M.H., Jiang J., Dong S., Lok T.M., Wu J., Cai H., Yeung E.S., Huang J., Chen J., Deng Y. and Huen M.S.Y., Critical roles of Ring Finger Protein RNF8 in replication stress responses, Journal of Biological Chemistry. 2011, 286: 22355-22361. |
| Sy M.H., Chen J. and Huen M.S.Y., The 53BP1-EXPAND1 connection in chromatin structure regulation., Nucleus. 2010, 1(6): 472-474. |
| Researcher : Hugon J |
| Project Title: | Society for Neuroscience 30th Annual Meeting Tau Phosphorylation during neuronal Apoptosis Induced by NMDA Receptor Blockade: an in Vivo Study |
| Investigator(s): | Hugon J |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 11/2000 |
| Researcher : Hung CHL |
| List of Research Outputs |
| Hung C.H.L., Cheung Y.T., Wuwongse S., Zhang Q. and Chang R.C.C., Relationship between low molecular weight beta-amyloid peptide-induced fission/fusion imbalance and mitochondrial functions, Society for Neuroscience 2010, San Diego, USA. 2010, 247.15/H61. |
| Researcher : Hung HL |
| List of Research Outputs |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime MTOR suppression in low molecular weight Ab induced autophagy, Alzheimer's & Dementia. 2010, 6(4) Supplement: S243. |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime mTOR suppression in low molecular weight Abeta induced autophagy, Alzheimer's and Dementia (Suppl. 1). 2010, S243. |
| Chang R.C.C., Zhang Q., Hung H.L., Wuwongse S. and Ho Y.S., Mechanisms of cell death in Alzheimer's disease, The Eighth Asia Pacific Multidisciplinary Meeting for Nervous System Diseases, Jan. 7-8, 2011 Hong Kong. 2011, 23. |
| Chang R.C.C., Zhang Q., Hung H.L. and Ho Y.S., Molecular mechanisms of initiating autophagy by oligomeric beta-amyloid peptide., The Croucher Foundation Conference, Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insightes. 2011, 19. |
| Chang R.C.C., Zhang Q., Hung H.L. and Cheung Y.T., Perturbation of endoplasmic reticulum and mitochondria rather than reduced activity of mTOR trigger autophagy in neurons exposed to low molecular weight beta-amyloid peptide, Society for Neuroscience 2010, San Diego, USA. 2010, 247.14/H60. |
| Chang R.C.C., Zhang Q., Hung H.L., Ho Y.S. and Wuwongse S., Signaling mechanism from endoplasmic reticulum collapse to induction of autophagy in neurons stressed with low molecular weight beta-amyloid peptides, The 10th International Conference on Alzheimer's & Parkinson's Disease, Barcelona, March 9-13, 2011. Abstract 350. |
| Chang R.C.C., Hung H.L., Wuwongse S., Zhang Q. and Ho Y.S., Stress responses of mitochondria to beta-amyloid peptide in Alzheimer's disease: do we understand the biological mechanisms now?, Croucher Advanced Study Institutes in Stress Responses of Mitochondria in Diabetes and Aging.. 2011. |
| Cheung Y...T..., Zhang Q., Hung H.L., Lai S...W..., Yu M...S..., So K...F... and Chang R...C...C..., Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight b-amyloid peptide, Journal of Cellular and Molecular Medicine. 2011, 15(2): 244-257. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17. |
| Hung H.L., Cheung Y.T., Wuwongse S., Zhang Q., Ho Y.S. and Chang R.C.C., Mitochondria in Alzheimer's Disease: Relationship between morphology and functions, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P27. |
| Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54. |
| Wong G.T.H., Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone on cytoskeleton in dendrites and dendritic spines, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 67 P49. |
| Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Amyloid beta and corticosterone-mediated synaptic dysfunction, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 66 P46. |
| Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Chang R.C.C. and Law A.C.K., Neuroprotective role of antidepressants in amyloid and corticosterone-mediated synaptic dysfunction., The Croucher Foundation Conference: Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insights.. 2011, 29. |
| Wuwongse S., Hung H.L., Chang R.C.C. and Law A.C.K., The involvement of synaptic degeneration in major depressive disorder and antidepressant mechanisms of action., Society for Neuroscience 2010, San Diego, USA. 2010, 162.1/V9. |
| Zhang Q., Hung H.L., Ho Y.S., Wuwongse S. and Chang R.C.C., Aggregation of the endoplasmic reticulum triggered by oligomeric Ab could facilitate formation of autophagosomes, Sixth International Symposium on Healthy Aging, March 5-6, 2011 Hong Kong. 2011, 47. |
| Researcher : Jin Y |
| Project Title: | Cytogenetic and molecular genetic characterization of esophageal carcinomas |
| Investigator(s): | Jin Y, Kwong YL, Tsao GSW |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 10/2002 |
| List of Research Outputs |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Researcher : Kai AKL |
| List of Research Outputs |
| Cheng L., Yeung P.K.K., Kai A.K.L., Chung S.S.M. and Chung S.K., Role of Epac in the pathogenesis of ischemic stroke, 15th Research Postgraduate Symposium, Dec. 1-2, 2010, The University of Hong Kong, Hong Kong. 2010, 82. |
| Researcher : Kong HML |
| List of Research Outputs |
| Kong H.M.L., Adrenomedullin: distribution in the male accessory sex glands of the rat and the effects of adrenomedullin in the seminal fluid on the female reproductive tract. 2011, 126 pages. |
| Researcher : Kong LHM |
| List of Research Outputs |
| Kong L.H.M., O W.S. and Tang F., Anti-oxidative and anti-inflammatory activities of adrenomedullin (ADM) in the rat uterus, Abstracts of the Society for the Study of Reproduction, 43rd Annual Meeting, 2010. 78 346. |
| Researcher : Lai KW |
| List of Research Outputs |
| Yeung P.K.K., Lai K.W., Son H.J., Zhang X., Hwang O., Chung S.S.M. and Chung S.K., Aldose reductase-deficiency leads to more significant loss of dopaminergeric neurons with incresed levels of dopamine, tetrahydrobiopterin and free radical accumulation under experimental Parkinson's Disease condition, Society for Neuroscience 2010. |
| Researcher : Lai S.W. |
| List of Research Outputs |
| Cheung Y...T..., Zhang Q., Hung H.L., Lai S...W..., Yu M...S..., So K...F... and Chang R...C...C..., Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight b-amyloid peptide, Journal of Cellular and Molecular Medicine. 2011, 15(2): 244-257. |
| Researcher : Lai SW |
| List of Research Outputs |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime MTOR suppression in low molecular weight Ab induced autophagy, Alzheimer's & Dementia. 2010, 6(4) Supplement: S243. |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime mTOR suppression in low molecular weight Abeta induced autophagy, Alzheimer's and Dementia (Suppl. 1). 2010, S243. |
| Researcher : Lam PY |
| List of Research Outputs |
| Lee V.H.Y., Lee T.O., Chu J.Y.S., Lam P.Y., Siu K.Y., Vaudry H. and Chow B.K.C., An indispensable role of secretin in mediating the osmoregulatory functions of angiotensin II. , FASEB J. 2010, 24(12): 5024-5032. |
| Researcher : Lau CF |
| List of Research Outputs |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17. |
| Lau C.F., Ho Y.S., Poon C.H., Wuwongse S. and Chang R.C.C., Synaptic neuroprotective effect of testosterone in beta-amyloid-treated rat hippocampal neurons, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 57 P12. |
| Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54. |
| Researcher : Lau WM |
| Project Title: | Potential beneficial effect of Lycium barbarum polysaccharide on sociosexual behaviour of rats |
| Investigator(s): | Lau WM, So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2010 |
| Completion Date: | 06/2011 |
| List of Research Outputs |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Effect of corticosterone and paroxetine on masculine mating behavior: Possible involvement of neurogenesis, The Journal of Sexual Medicine. 2011, 8: 1390-1403. |
| Lau W.M., Lee C.D., Yau S.Y., Chang R.C.C. and So K.F., Facilitation of male sexual behavior by lycium barbarum (wolfberry) polysaccharide, The Consortium for Globalizaiton of Chinese Medicine. Aug. 23-25, 2010 Hong Kong. 2010, 106 No. 126. |
| Lau W.M., Ren C., Yang J., Yan S.W.L., Chang R.C.C., Pu M. and So K.F., Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal Mongolian gerbil (Meriones unguiculatus), Cell Transplantation. 2011, 20: 871-881. |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Possible involvement of neurogenesis in male rat mating behavior, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 141. |
| Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating β-catenin expression, Neurochemistry International . 2011, 59(2): 114-121. |
| Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 promote astroglial differentiation of neural stem/progenitor cells through modulating Notch1/NICD and Hes1 expressions, Biochemical and Biophysical Research Communications. 2011, 407: 517-524. |
| Luan L., Ren C., Lau W.M., Yang J., Pickard G.E., So K.F. and Pu M., Y-like retinal ganglion cells innervate the dorsal raphe nucleus in the Mongolian gerbils (Meriones unguiculatus), PLoS ONE. 2011, 6(4): e18938. |
| Ren C., Lau W.M., Luan L., Yang J., So K.F. and Pu M., Mongolian gerbil as a seasonal affective disorder animal model, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 140. |
| Tang S.W., So K.F., Helmeste D.M., Lau W.M., Yau S.Y. and Lee T.M.C., Is adult neurogenesis relevant in human depression?, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 142. |
| Zhang E., Yau S.Y., Lau W.M., Lee T.M.C., Chang R.C.C. and So K.F., Promotion of neurogenesis and preservation of dendrites by wolfberry in experimental depression, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 208. |
| Researcher : Lee CD |
| List of Research Outputs |
| Lee C.D., Mild stress –induced hippocampal cell proliferation and dendritic complexity is associated with improved spatial learning in rats, Journal of Indian Academy of Neurosciences. 2010, 17: 21. |
| Researcher : Lee CW |
| List of Research Outputs |
| Lee C.W., The characterization of the LKB1-AMPK pathway in hepatocellular carcinoma . 2010, 215 pages. |
| Researcher : Lee DTW |
| List of Research Outputs |
| Luk S.U., Lee K.W., Liu J.I., Lee D.T.W., Chiu Y.T., Ma S.K.Y., Ng I.O.L., Wong Y.C., Chan F.L. and Ling M.T., Chemopreventive effect of PSP through targeting of prostate cancer stem cell-like population, PLoS One. 2011, 6: e19804. |
| Researcher : Lee LS |
| List of Research Outputs |
| Li G., Lee L.S., Li M., Tsao G.S.W. and Chiu J., Molecular changes during arsenic-induced cell transformation, Journal of Cellular Physiology. 2011, in press. |
| Researcher : Leong VYL |
| List of Research Outputs |
| Mak W.Y.G., Chan M.L., Leong V.Y.L., Lee M.F., Yau T.O., Ng I.O.L. and Ching Y.P., Overexpression of a novel activator of PAK4, the CDK5 kinase-associated protein CDK5RAP3, promotes hepatocellular carcinoma metastasis, Cancer Research. 2011, 71: 2949-58. |
| Researcher : Leung KM |
| List of Research Outputs |
| Huen M.S.Y., Sy S.M.H., Leung K.M., Ching Y.P., Tipoe G.L., Man C., Dong S. and Chen J., SON is a spliceosome-associated factor required for mitotic progression, CELL CYCLE. 2010, 9(13): 2679-2685. |
| Researcher : Leung TM |
| List of Research Outputs |
| Leung T.M., Fung M.L., Liong E.C., Lau T.Y.H., Nanji A.A. and Tipoe G.L., Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice, Histology and Histopathology. 2011, 26: 201-211. |
| Researcher : Li B |
| Project Title: | PI3K/AKT pathway as a therapeutic target in human esophageal cancer |
| Investigator(s): | Li B, Cheung A, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2010 |
| List of Research Outputs |
| Cheung A., Li B., Chan K.W. and Tsao G.S.W., IGF1R-targeting as potential immunotherapy for esophageal cancer, 2nd International Cancer Immunotherapy and Immujomonitoring Conference, May 2-5, Budapest, Hungary. 2011, 70. |
| Li J., Li B., Tsao G.S.W. and Cheung A., Role of AMPK-mTOR signaling in anticancer effects of silibinin on esophageal squamous cell carcinoma, Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, April 2-6, 2011 U.S.A.. 2011. |
| Researcher : Li J |
| List of Research Outputs |
| Chan K.C., Li J., Lui Kau K.W.F., Zhou I.Y., Cheung M.M.H., Lau C., Yang J., So K.F. and Wu E.X., In vivo retinotopic mapping of superior colliculus using manganese-enhanced magnetic resonance imaging, NeuroImage. 2011, 54: 389-395. |
| Li J., Li B., Tsao G.S.W. and Cheung A., Role of AMPK-mTOR signaling in anticancer effects of silibinin on esophageal squamous cell carcinoma, Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, April 2-6, 2011 U.S.A.. 2011. |
| Researcher : Li J |
| List of Research Outputs |
| Chan K.C., Li J., Lui Kau K.W.F., Zhou I.Y., Cheung M.M.H., Lau C., Yang J., So K.F. and Wu E.X., In vivo retinotopic mapping of superior colliculus using manganese-enhanced magnetic resonance imaging, NeuroImage. 2011, 54: 389-395. |
| Li J., Li B., Tsao G.S.W. and Cheung A., Role of AMPK-mTOR signaling in anticancer effects of silibinin on esophageal squamous cell carcinoma, Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, April 2-6, 2011 U.S.A.. 2011. |
| Researcher : Liang Y |
| List of Research Outputs |
| Chiu K., Liang Y., Chang R.C.C. and So K.F., Lycium barbarum L.: a neuroprotective drug for glaucoma, 枸杞子–青光眼的神经保护剂, Ophthalmol CHN. 眼科, BeiJing CHN, 2011, 20(1): 21-27. |
| Researcher : Liao S |
| List of Research Outputs |
| Liao S., Ho J.C.M., Tang F. and O W.S., Adrenomedullin increases ciliary beat frequency and decreases muscular contraction in the rat oviduct, Reproduction. 2011, 141: 367-372. |
| Researcher : Lin B |
| Project Title: | Remodeling of retinal cone bipolar cells in mouse models of rd |
| Investigator(s): | Lin B |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2010 |
| Project Title: | Restoring visual function after photoreceptor degeneration: ectopic expression of photosensitive proteins in retinal neurons. |
| Investigator(s): | Lin B |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | ARVO Annual Meeting 2011 Remodeling of cone bipolar cells in the mouse model of retinitis pigmentosa |
| Investigator(s): | Lin B |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| Project Title: | Mechanisms of the Secondary Degeneration of Retinal Cone Photoreceptors in Retinitis Pigmentosa (RP) |
| Investigator(s): | Lin B |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2011 |
| List of Research Outputs |
| Lin B. and Masland R.H., Restoring visual function after photoreceptor degeneration: ectopic expression of photosensitive proteins in retinal neurons. , In: Chambers JJ and Kramer RH, Photosensitive Molecular for controlling Biological Function. In press. . New Jersey, USA, Humana Press, 2010. |
| Researcher : Ling MT |
| Project Title: | The regulation and role of Id-1 in prostate cancer progression |
| Investigator(s): | Ling MT, Wong YC, Wang X |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2005 |
| Project Title: | The role of EMI1 in prostate carcinogenesis |
| Investigator(s): | Ling MT, Wang X |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2007 |
| Project Title: | The role of Daxx in chromosome instability and prostate carcinogenesis |
| Investigator(s): | Ling MT, Wong YC |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2008 |
| Project Title: | Effect of Tocotrienol in the inhibition of hormone refractory prostate cancer |
| Investigator(s): | Ling MT, Wong YC |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 08/2008 |
| List of Research Outputs |
| Chua C.W., Chiu Y.T., Yuen H.F., Chan K.W., Wang X., Ling M.T. and Wong Y.C., Differential expression of MSX2 in nodular hyperplasia, high-grade prostatic intraepithelial neoplasia and prostate adenocarcinoma, APMIS. 2010, 118(12): 918-26. |
| Researcher : Liong EC |
| List of Research Outputs |
| Leung T.M., Fung M.L., Liong E.C., Lau T.Y.H., Nanji A.A. and Tipoe G.L., Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice, Histology and Histopathology. 2011, 26: 201-211. |
| Researcher : Liu J |
| List of Research Outputs |
| Liu J., Chung S.S.M. and Chung S.K., Role of Epac1 in pathogenesis of diabetic retinopathy, 15th Research Postgraduate Symposium, Dec. 1-2, 2010, The University of Hong Kong, Hong Kong. 2010, 87. |
| Researcher : Liu M |
| List of Research Outputs |
| Liu M., The expression of Id2 and its potential roles in the regulation of neural stem/progenitor cells in the subventricular zone of the adult mouse. 2010, 104 pages. |
| Yip H.K.F. and Liu M., Id2 expression profile and potential role in the regulation of neural stem cells in the subventriclar zone of adult mouse brain, Adult Neurogenesis. 2011, 89 Poster No. 325. |
| Yip H.K.F. and Liu M., The expression of Id2 and its potential roles in the regulation of neural stem/progenitor cells in the subventricular zone of adult mouse brain, Keystone Symposia on Molecular and Cellular Biology, Adult Neurogenesis, Taos, New Mexico, USA. 2011. |
| Researcher : Lok CKM |
| List of Research Outputs |
| Chan T.F., Chiu K., Lok C.K.M., Lok C.K.M., Ho Y.S., So K.F. and Chang R.C.C., Loss of neurons in the inner retinal neuron of transgenic mice bearing human mutated amyloid precursor protein., Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P25. |
| Chiu K., Leung I.Y.P., Lui J.C.H., Lok C.K.M., Ho Y.S., Baum L., So K.F. and Chang R.C.C., Morphometric analysis of inner retinal layer in a mouse model of Alzheimer’s disease. , Society for Neuroscience . 2010, 457.17/L9. |
| Chiu K., Yeung S.C., Lok C.K.M., Zhou Y., Chang R.C.C. and So K.F., Neuroimmune responses of polysacharides from lycium barbarum (wolfberry) in retina after experimental glaucoma, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010 Hong Kong. 2010, 102 No.121. |
| Chiu K., Lok C.K.M., Chang R.C.C. and So K.F., Wolfberry polysaccharide stimulates anti-stress capacity in retina against glaucoma. , Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 48 OP7. |
| Researcher : Lok TM |
| List of Research Outputs |
| Sy M.H., Jiang J., Dong S., Lok T.M., Wu J., Cai H., Yeung E.S., Huang J., Chen J., Deng Y. and Huen M.S.Y., Critical roles of Ring Finger Protein RNF8 in replication stress responses, Journal of Biological Chemistry. 2011, 286: 22355-22361. |
| Researcher : Lui Kau KWF |
| List of Research Outputs |
| Chan K.C., Li J., Lui Kau K.W.F., Zhou I.Y., Cheung M.M.H., Lau C., Yang J., So K.F. and Wu E.X., In vivo retinotopic mapping of superior colliculus using manganese-enhanced magnetic resonance imaging, NeuroImage. 2011, 54: 389-395. |
| Researcher : Luk SU |
| List of Research Outputs |
| Luk S.U., Lee K.W., Liu J.I., Lee D.T.W., Chiu Y.T., Ma S.K.Y., Ng I.O.L., Wong Y.C., Chan F.L. and Ling M.T., Chemopreventive effect of PSP through targeting of prostate cancer stem cell-like population, PLoS One. 2011, 6: e19804. |
| Luk S.U. and Ching Y.P., Hepatitis B virus promotes hepatocarcinogenesis by activation of Pak1, In: Hong Kong Government , Health Research Symposium 2010: Improving health and recognising excellence . 2010. |
| Researcher : Luk SU |
| List of Research Outputs |
| Luk S.U., Lee K.W., Liu J.I., Lee D.T.W., Chiu Y.T., Ma S.K.Y., Ng I.O.L., Wong Y.C., Chan F.L. and Ling M.T., Chemopreventive effect of PSP through targeting of prostate cancer stem cell-like population, PLoS One. 2011, 6: e19804. |
| Luk S.U. and Ching Y.P., Hepatitis B virus promotes hepatocarcinogenesis by activation of Pak1, In: Hong Kong Government , Health Research Symposium 2010: Improving health and recognising excellence . 2010. |
| Researcher : Mak W.Y.G. |
| List of Research Outputs |
| Deng W..., Tsao G...S...W..., Mak W...Y...G..., Tsang C...M..., Ching Y...P..., Guan X..., Huen M...S...Y... and Cheung A..., Impact of G2 checkpoint defect on centromeric instability, Oncogene. 2011, 30: 1281-1289. |
| Researcher : Mak WYG |
| List of Research Outputs |
| Mak W.Y.G., Functional characterization of CDK5RAP3 in hepatocellular carcinoma and neuronal differentiation. 2010, 222 pages. |
| Mak W.Y.G., Chan M.L., Leong V.Y.L., Lee M.F., Yau T.O., Ng I.O.L. and Ching Y.P., Overexpression of a novel activator of PAK4, the CDK5 kinase-associated protein CDK5RAP3, promotes hepatocellular carcinoma metastasis, Cancer Research. 2011, 71: 2949-58. |
| Researcher : Man CWY |
| Project Title: | The polycomb group protein, Bmi-1, induces supernumerary centrosomes and chromosome instability through Id1 in immortalized nasopharyngeal epithelial cells |
| Investigator(s): | Man CWY, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2007 |
| List of Research Outputs |
| Cheung P.P.Y., Deng W., Man C.W.Y., Tse W.W., Srivastava G., Law S.Y.K., Tsao G.S.W. and Cheung A., Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: Implications for carcinogenesis, Cancer Letters. 2010, 293(1): 41-51. |
| Researcher : Mok K.H. |
| List of Research Outputs |
| Mok K...H..., Chung C.S.T. and Kwok T.W.K., A simple clinical test for perception of progressive addition lens peripheral image blue. A pilot study, Journal of Optometry. 2011, 4(1): 30-34. |
| Researcher : Mok KH |
| List of Research Outputs |
| Mok K.H. and Chung C.S.T., Seven-year retrospective analysis of the myopic control effect of orthokeratology in children: a pilot study, Clinical Optometry. 2011, 3: 1-4. |
| Researcher : Nal-Rogier BTM |
| List of Research Outputs |
| Teoh K.T., Siu Y.L., Chan W.L., Schlüter M.A., Liu C.J., Peiris J.S.M., Bruzzone R., Margolis B. and Nal-Rogier B.T.M., The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis., In: Asma Nusrat, Molecular Biology of the Cell. 2010, 21: 3838-3852. |
| Researcher : Nian S |
| List of Research Outputs |
| Lo A.C.Y., Wong C.H., Nian S., Cheung P.T., Chan B.P. and Wong D.S.H., A cell-based drug delivery system using collagen-alginate composite matrix: in vitro and in vivo studies, 2011 Congress of the Asia-Pacific Academy of Ophthalmology. 2011. |
| Researcher : Niu C |
| List of Research Outputs |
| Niu C., The neuroprotective signaling mechanisms of telomerase via the induction by brain-derived neurotrophic factor (BDNF) in nervous system injury. 2010, 227 pages. |
| Niu C. and Yip H.K.F., The neuroprotective signaling mechanisms of telomerase via the induction by brain-derived neurotrophic factor in rat spinal cord motor neurons, Society of Neuroscience Annual Meeting, November 2010. Program No. 470.13: Poster No. FF6. |
| Niu C. and Yip H.K.F., The neuroprotective signaling mechanisms of telomerase via the induction by brain-derived neurotrophic factor in rat spinal cord motor neurons, USA Society of Neuroscience Annual Meeting. 2010. |
| Researcher : O WS |
| Project Title: | Adrenomedullin in the female reproductive system: gene expression in the ovary and the uterus, possible roles in reproduction and interactions with endothelin-1 and gonadotrophins. |
| Investigator(s): | O WS, Tang F |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2007 |
| Completion Date: | 02/2011 |
| Project Title: | The functional significance of a novel uterine growth factor in embryo development |
| Investigator(s): | O WS, Chow PH |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2008 |
| Completion Date: | 08/2010 |
| Project Title: | The role of adrenomedullin in human oviduct |
| Investigator(s): | O WS, Tang F |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2009 |
| Completion Date: | 11/2011 |
| Project Title: | 43rd Society for the Study of Reproduction Annual meeting Adrenomedullin in the Rat Ovary: Its production, interaction with endothelin 1 and actions on progesterone secretion during gestation |
| Investigator(s): | O WS |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 07/2010 |
| Completion Date: | 08/2010 |
| Project Title: | A CASE-CONTROL IN-VITRO STUDY ON THE POSSIBLE ROLE OF ADRENOMEDULLIN AND ENDOTHELIN IN PATHOGENESIS OF TUBAL ECTOPIC PREGNANCY |
| Investigator(s): | O WS, Tang F |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2010 |
| List of Research Outputs |
| Kong L.H.M., O W.S. and Tang F., Anti-oxidative and anti-inflammatory activities of adrenomedullin (ADM) in the rat uterus, Abstracts of the Society for the Study of Reproduction, 43rd Annual Meeting, 2010. 78 346. |
| Li L., Tang F. and O W.S., Coexpression of adrenomedullin and its receptor component proteins in the reproductive system of the rat during gestation, Reproductive Biology and Endocrinology. 2010, 8: 130-142. |
| Liao S., Ho J.C.M., Tang F. and O W.S., Adrenomedullin increases ciliary beat frequency and decreases muscular contraction in the rat oviduct, Reproduction. 2011, 141: 367-372. |
| O W.S., Adrenomedullin in reproduction, The 6th International Huaxia Congress Abstract Book. 2010, 37 S-46. |
| O W.S., Li L. and Tang F., Adrenomedullin in the rat ovary: Its production, interaction with endothelin 1, and actions on progesterone secretion during gestation, Abstracts of the Society for the Study of Reproduction, 43rd Annual Meeting, 2010. 137 606. |
| O W.S., What are the roles of adrenomedullin in female reproduction?, The Annual Scientific Meeting 2010, Hong Kong Society of Endocrinology, Metabolism and Reproduction. 2010, 1. |
| Zhao W., Fung Y.S. and O W.S., Assessment Of The Mitochondria Number Based On Cardiolipin By Capillary Electrophoresis-LIF Detection, Abstract of the 10th Asian-Pacific International Symposium on Microscale Separations and Analysis (APCE 2010), Hong Kong, China, Dec. 10-13, 2010. PA17, Page 89. |
| Zhao W., Sun H., Fung Y.S. and O W.S., Piezoelectric quartz crystal biosensor for assessing mitochondria extracted from cell based on its cardiolipin content, Abstract of Recent Advance in Bioanalysis Symposium, 2010 Int. Chem. Soc. Pacif. Basin Soc. (Pacifichem 2010), Honolulu, Hawaii, USA, Dec. 15-20, 2010. ANYL Paper 773. |
| Researcher : Poon CH |
| List of Research Outputs |
| Lau C.F., Ho Y.S., Poon C.H., Wuwongse S. and Chang R.C.C., Synaptic neuroprotective effect of testosterone in beta-amyloid-treated rat hippocampal neurons, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 57 P12. |
| Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54. |
| Researcher : Poon CH |
| List of Research Outputs |
| Lau C.F., Ho Y.S., Poon C.H., Wuwongse S. and Chang R.C.C., Synaptic neuroprotective effect of testosterone in beta-amyloid-treated rat hippocampal neurons, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 57 P12. |
| Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54. |
| Researcher : Pu M |
| List of Research Outputs |
| Lau W.M., Ren C., Yang J., Yan S.W.L., Chang R.C.C., Pu M. and So K.F., Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal Mongolian gerbil (Meriones unguiculatus), Cell Transplantation. 2011, 20: 871-881. |
| Ren C., Lau W.M., Luan L., Yang J., So K.F. and Pu M., Mongolian gerbil as a seasonal affective disorder animal model, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 140. |
| Researcher : So K.F. |
| Project Title: | Nanobiomedical manufacturing: the workforce of tomorrow |
| Investigator(s): | So KF, Ellis-Behnke RG, Tay DKC, Liang Y |
| Department: | Anatomy |
| Source(s) of Funding: | Innovation and Technology Support Programme |
| Start Date: | 09/2006 |
| Project Title: | Investigate retinal neuromechanisms of seasonal affective disorder |
| Investigator(s): | So KF, Yang J, Xiao CX, Nan Y |
| Department: | Anatomy |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2009 |
| Completion Date: | 12/2010 |
| Project Title: | RAGE (receptor for advanced glycation end products), Abeta (beta-amyloid peptide) and ET-1 (endothelin-1) probing their effects in glaucoma with transgenic mice over-expressing ET-1 in endothelial or glial cells |
| Investigator(s): | So KF, Chung SK, Lo ACY |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | Steroid therapy: effect of corticosteroid and antidepressant on sexual behavior |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Project Title: | Neuroprotective effect of physical exercise on stressed animal model |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2010 |
| Project Title: | Role of JNK3/APP signaling pathway in modulating the apoptosis of optic axotomized retinal ganglion cells |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Use of induced pluripotent stem cells to study pathology of dominant optic atrophy: From Opa1 mutation, mitochondrial damage, to optic nerve atrophy |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Travel Grants for NSFC/RGC JRS |
| Start Date: | 12/2010 |
| Project Title: | Assessment of neurogenesis in an animal model of seasonal affective disorder. |
| Investigator(s): | So KF, Lau WM |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2011 |
| Project Title: | World Glaucoma Congress 2011 Neuroprotective Effect of an Anti-Aging Chinese Medicine, Wolfberry, on Glaucoma |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 06/2011 |
| Completion Date: | 07/2011 |
| List of Research Outputs |
| Cheung Y...T..., Zhang Q., Hung H.L., Lai S...W..., Yu M...S..., So K...F... and Chang R...C...C..., Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight b-amyloid peptide, Journal of Cellular and Molecular Medicine. 2011, 15(2): 244-257. |
| Kwok V...P...Y..., Niu Z., Kay P., Zhou K., Mo L., Jin Z., So K...F... and Tan L..., Learning new color names produces rapid increase in gray matter in the intact adult human cortex, Proc Natl Acad Sci USA.. 2011, 108: 6686–6688. |
| Researcher : So KF |
| Project Title: | Nanobiomedical manufacturing: the workforce of tomorrow |
| Investigator(s): | So KF, Ellis-Behnke RG, Tay DKC, Liang Y |
| Department: | Anatomy |
| Source(s) of Funding: | Innovation and Technology Support Programme |
| Start Date: | 09/2006 |
| Project Title: | Investigate retinal neuromechanisms of seasonal affective disorder |
| Investigator(s): | So KF, Yang J, Xiao CX, Nan Y |
| Department: | Anatomy |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2009 |
| Completion Date: | 12/2010 |
| Project Title: | RAGE (receptor for advanced glycation end products), Abeta (beta-amyloid peptide) and ET-1 (endothelin-1) probing their effects in glaucoma with transgenic mice over-expressing ET-1 in endothelial or glial cells |
| Investigator(s): | So KF, Chung SK, Lo ACY |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | Steroid therapy: effect of corticosteroid and antidepressant on sexual behavior |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Project Title: | Neuroprotective effect of physical exercise on stressed animal model |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2010 |
| Project Title: | Role of JNK3/APP signaling pathway in modulating the apoptosis of optic axotomized retinal ganglion cells |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Use of induced pluripotent stem cells to study pathology of dominant optic atrophy: From Opa1 mutation, mitochondrial damage, to optic nerve atrophy |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Travel Grants for NSFC/RGC JRS |
| Start Date: | 12/2010 |
| Project Title: | Assessment of neurogenesis in an animal model of seasonal affective disorder. |
| Investigator(s): | So KF, Lau WM |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2011 |
| Project Title: | World Glaucoma Congress 2011 Neuroprotective Effect of an Anti-Aging Chinese Medicine, Wolfberry, on Glaucoma |
| Investigator(s): | So KF |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 06/2011 |
| Completion Date: | 07/2011 |
| List of Research Outputs |
| Chan B.P., Chan C.M. and So K.F., Collagen-Based Microspheres and Methods for Preparation and Use., Us Patent No. 7,931,918 (issued on 26 April 2011). 2011. |
| Chan B.P., Chan M.C. and So K.F., Collagen-based microspheres and methods of preparation and uses thereof. 2011, United States Patent No. US 7,931,918 B2. |
| Chan K.C., Cheung M.M.H., Xing K., Zhou I.Y., Chow A.M.K., Lau C., So K.F. and Wu E.X., In vivo MRI study of the visual system in normal, developing and injured rodent brains, 32nd Annual International Conference of the IEEE EMBS Buenos Aires, Argentina, Auguest 31 - September 4, 2010. 2010, 5689-5692. |
| Chan K.C., Li J., Lui Kau K.W.F., Zhou I.Y., Cheung M.M.H., Lau C., Yang J., So K.F. and Wu E.X., In vivo retinotopic mapping of superior colliculus using manganese-enhanced magnetic resonance imaging, NeuroImage. 2011, 54: 389-395. |
| Chan T.F., Chiu K., Lok C.K.M., Lok C.K.M., Ho Y.S., So K.F. and Chang R.C.C., Loss of neurons in the inner retinal neuron of transgenic mice bearing human mutated amyloid precursor protein., Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P25. |
| Chang R.C.C., Ho Y.S., Chiu K. and So K.F., Our experience of anti-Chinese medicine research to prevent aging-associated neurodegeneration. , The 2nd Macao Forum on Chinese Medical Sciences, Nov. 8-11, 2010 Macau. 2010. |
| Chiu K., So K.F. and Chang R.C.C., Immune modulation in glaucoma – can manipulation of microglia activation help?, Glaucoma / Book 2. University Campus STeP Ri, InTech, 2011. |
| Chiu K., Liang Y., Chang R.C.C. and So K.F., Lycium barbarum L.: a neuroprotective drug for glaucoma, 枸杞子–青光眼的神经保护剂, Ophthalmol CHN. 眼科, BeiJing CHN, 2011, 20(1): 21-27. |
| Chiu K., Leung I.Y.P., Lui J.C.H., Lok C.K.M., Ho Y.S., Baum L., So K.F. and Chang R.C.C., Morphometric analysis of inner retinal layer in a mouse model of Alzheimer’s disease. , Society for Neuroscience . 2010, 457.17/L9. |
| Chiu K., Chan T.F., Wu A., Leung I.Y.P., So K.F. and Chang R.C.C., Neurodegeneration of the retina in mouse models of Alzheimer’s disease: What can we learn from the retina?, Age. Springer, 2011. |
| Chiu K., Yeung S.C., Lok C.K.M., Zhou Y., Chang R.C.C. and So K.F., Neuroimmune responses of polysacharides from lycium barbarum (wolfberry) in retina after experimental glaucoma, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010 Hong Kong. 2010, 102 No.121. |
| Chiu K., Chan T.F., So K.F. and Chang R.C.C., Retinal neurodegeneration in AD transgenic mice, 从AD动物模型研究 视网膜神经细胞退化 , Joint seminar College of life sciences ShenZhen University/ HKU. 2011. |
| Chiu K., Lok C.K.M., Chang R.C.C. and So K.F., Wolfberry polysaccharide stimulates anti-stress capacity in retina against glaucoma. , Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 48 OP7. |
| Ho Y.S., So K.F. and Chang R.C.C., Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia, Chinese Medicine. 2011, 6: 1-6. |
| Ho Y.S., Chao J., So K.F. and Chang R.C.C., The holistic approach of anti-aging lycium barbarum (wolfberry) in the protection against pathological factors related to Alzheimer's disease, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010, Hong Kong. 2010, 102 No. 120. |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Effect of corticosterone and paroxetine on masculine mating behavior: Possible involvement of neurogenesis, The Journal of Sexual Medicine. 2011, 8: 1390-1403. |
| Lau W.M., Lee C.D., Yau S.Y., Chang R.C.C. and So K.F., Facilitation of male sexual behavior by lycium barbarum (wolfberry) polysaccharide, The Consortium for Globalizaiton of Chinese Medicine. Aug. 23-25, 2010 Hong Kong. 2010, 106 No. 126. |
| Lau W.M., Ren C., Yang J., Yan S.W.L., Chang R.C.C., Pu M. and So K.F., Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal Mongolian gerbil (Meriones unguiculatus), Cell Transplantation. 2011, 20: 871-881. |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Possible involvement of neurogenesis in male rat mating behavior, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 141. |
| Leung C.K.S., Weinreb R.N., Li Z.W., Liu S., Lindsey J.D., Choi N., Liu L., Cheung C.Y.L., Ye C., Qiu K., Chen L.J., Yung W.H., Growston J.G., Pu M., So K.F., Pang C.P. and Lam D.S.C., Long-term in vivo imaging and measurement of dendritic shrinkage of retinal ganglion cells, Investigative Ophthalmology & Visual Science. 2011, 52(3): 1539-1547. |
| Li S.Y., Yang D., Yeung C.M., Yu W.Y., Chang R.C.C., So K.F., Wong D.S.H. and Lo A.C.Y., Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury, PLoS One. 2011, 6(1): e16380. |
| Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating β-catenin expression, Neurochemistry International . 2011, 59(2): 114-121. |
| Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 promote astroglial differentiation of neural stem/progenitor cells through modulating Notch1/NICD and Hes1 expressions, Biochemical and Biophysical Research Communications. 2011, 407: 517-524. |
| Liao X.X., Chen D., Shi J., Sun Y.Q., Sun S.J., So K.F. and Fu Q., The expression patterns of Nogo-A, myelin associated glycoprotein and oligodendrocyte myelin glycoprotein in the retina after ocular hypertension, Neurochemistry Research. 2011, 36: 1955-1961. |
| Lin J., Lam M.M.L., Chiu C., Tse M., Khong P.L., Chan C., So K.F., Chan K.W., Chang W.C. and Chen E.Y.H., The impacts of yoga and exercise on neurocognitive function and symptoms in early psychosis, Schizophrenia Bulletin. 2011, 37: 171. |
| Luan L., Ren C., Lau W.M., Yang J., Pickard G.E., So K.F. and Pu M., Y-like retinal ganglion cells innervate the dorsal raphe nucleus in the Mongolian gerbils (Meriones unguiculatus), PLoS ONE. 2011, 6(4): e18938. |
| Luo Z., Lai M., Cheung M., Han S., Zhang T., Luo Z., Ting J.W.M., Wong P.W.L., Chan K.Y., So K.F. and Tipoe G.L., Developing local association network based IoT solutions for body parts tagging and tracking, 42 International Journal of Systems and Service-Oriented Engineering. 2010, 1(4): 42-64. |
| Qiu G., Wan R., Hu J., Mattson M.P., Spangler E., Liu S., Yau S.Y., Lee T.M.C., Gleichmann M., Ingram D.K., So K.F. and Zou S., Adiponectin protects rat hippocampal neurons against excitotoxicity, Age. 2011, 33: 155-165. |
| Ren C., Lau W.M., Luan L., Yang J., So K.F. and Pu M., Mongolian gerbil as a seasonal affective disorder animal model, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 140. |
| So K.F., Adult neurogenesis and depression, 2010 International Symposium on Brain Function and Health, Nov. 29 - Dec. 1, 2010, Jinan, China. 2010, 17-18. |
| So K.F. and Chang R.C.C., Ginseng, Wolfberry, Bilberry in “Section 8: Non-pharmaceutical Medications and Approaches”, In: R.N. Weinreb & J. Liebmann , Medical Treatment of Glaucoma: World Glaucoma Association Consensus Series 7. Kugler Publication, 2010, 321-328. |
| So K.F. and Chang R.C.C., Molecular basis of neuroprotection in neurodegenerative diseases using Gouqizi (Wolfberry), The 4th Pan Pacific Symposium on Stem Cells and Cancer Researches, April 15-18, 2011 Taiwan.. 2011. |
| So K.F. and Chang R.C.C., Molecular mechanism of neuroprotection in neurodegenerative diseases using Gouqizi (Wolfberry), The 5th Beijing International Forum on Rehabilitation, Oct. 29 - Nov. 1, 2010, Beijing, China. 2010, 33-34. |
| So K.F., Neuroprotection in glaucoma using Gouqizi (Wolfberry), The International Symposium on Ocular Pharmacology and Therapeutics, December 9-11, 2010, Macau, China. 2010, 48. |
| So K.F. and Chang R.C.C., Neuroprotection in glaucoma using Gouqizi (Wolfberry), 首都醫科大學眼科學院２０１０年學朮年会. 2010, 15. |
| So K.F., Promotion of neurogenesis and preservation of dendrites by anti-aging Lycium Barbarum (Wolfberry) in experimental depression, Xiangshan Science Conferences, The 392nd Session: Brain and Cognitive Sciences, April 8-9, 2011, Hong Kong. 2011, 21-22. |
| Tang S.W., So K.F., Helmeste D.M., Lau W.M., Yau S.Y. and Lee T.M.C., Is adult neurogenesis relevant in human depression?, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 142. |
| Yang D., Yeung C.M., Li S.Y., Chang R.C.C., So K.F., Wong D.S.H. and Lo A.C.Y., Lycium barbarum polysaccharides protect brain from cerebral edema and blood-brain barrier disruption after ischemia/reperfusion injury, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 56 P6. |
| Yip K.K., Lo S.C.L., Leung M.C.P., So K.F., Tang C.Y. and Poon D.M.Y., The effect of low-energy laser irradiation on apoptotic factors following experimentally induced transient cerebral ischemia, Neuroscience. 2011, 190: 301-306. |
| Yu W.Y., Grierson I., Sheridan C.M., Lo A.C.Y., So K.F. and Wong D.S.H., Bovine corneal endothelial precursors isolated by sphere-forming assay, UK National; Stem Cell Network Scientific Conference 2011. |
| Yuan Q.J., Hu B., Chu T.H., Su H., Zhang W., So K.F., Lin Z. and Wu W., Co-expression of GAP-43 and nNOS in avulsed motoneurons and their potential role for motoneuron regeneration, Nitric Oxide. 2010, 23: 258-263. |
| Zhang E., Yau S.Y., Lau W.M., Lee T.M.C., Chang R.C.C. and So K.F., Promotion of neurogenesis and preservation of dendrites by wolfberry in experimental depression, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 208. |
| Researcher : Su H |
| Project Title: | Survival, axonal extension and target innervation of murine iPS-induced motoneurons after transplantation into avulsion-injured spinal cords with ventral root reimplantation |
| Investigator(s): | Su H, Wu W |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2009 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Sang Y., Su H., Yang X., Liu L.G., Wu W. and Cheung R.T.F., Neural stem cell transplantation in a rat model of intracerebral haemorrhage plus haematoma aspiration, Sixteenth Medical Research Conference. 2011, 17 (Suppl 1): 51. |
| Yuan Q.J., Hu B., Chu T.H., Su H., Zhang W., So K.F., Lin Z. and Wu W., Co-expression of GAP-43 and nNOS in avulsed motoneurons and their potential role for motoneuron regeneration, Nitric Oxide. 2010, 23: 258-263. |
| Researcher : Sy MH |
| Project Title: | Understanding the regulatory mechanisms that govern the PALB2-dependent DNA repair pathway |
| Investigator(s): | Sy MH, Huen MSY |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2010 |
| List of Research Outputs |
| Dray E., Etchin J., wiese C., Saro D., William G.J., Hammel M., Yu X., Galkin V.E., Liu D., Tsai M.S., Sy M.H., Schild D., egelman E., chen J. and Sung P., Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2., Nat Struct Mol Biol. 2010, 17: 1255-9. |
| Sy M.H., Jiang J., Dong S., Lok T.M., Wu J., Cai H., Yeung E.S., Huang J., Chen J., Deng Y. and Huen M.S.Y., Critical roles of Ring Finger Protein RNF8 in replication stress responses, Journal of Biological Chemistry. 2011, 286: 22355-22361. |
| Sy M.H., Chen J. and Huen M.S.Y., The 53BP1-EXPAND1 connection in chromatin structure regulation., Nucleus. 2010, 1(6): 472-474. |
| Researcher : Sy SMH |
| Project Title: | Understanding the regulatory mechanisms that govern the PALB2-dependent DNA repair pathway |
| Investigator(s): | Sy MH, Huen MSY |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2010 |
| List of Research Outputs |
| Huen M.S.Y., Sy S.M.H., Leung K.M., Ching Y.P., Tipoe G.L., Man C., Dong S. and Chen J., SON is a spliceosome-associated factor required for mitotic progression, CELL CYCLE. 2010, 9(13): 2679-2685. |
| Researcher : Tang CM |
| List of Research Outputs |
| Hong B., Lui V.W.Y., Hui E.P., Ng M.H.L., Cheng S.H., Sung F.L., Tang C.M., Tsao G.S.W. and Chan A.T.C., Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation, Invest New Drugs. 2011, 29: 401-410. |
| Researcher : Tang SW |
| List of Research Outputs |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Effect of corticosterone and paroxetine on masculine mating behavior: Possible involvement of neurogenesis, The Journal of Sexual Medicine. 2011, 8: 1390-1403. |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Possible involvement of neurogenesis in male rat mating behavior, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 141. |
| Tang S.W., So K.F., Helmeste D.M., Lau W.M., Yau S.Y. and Lee T.M.C., Is adult neurogenesis relevant in human depression?, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 142. |
| Researcher : Tang WH |
| List of Research Outputs |
| Tang W.H., Role of polyol pathway in ischemic and hyperglycemic cardiomyopathy. 2010, 180 pages. |
| Researcher : Ting JWM |
| List of Research Outputs |
| Luo Z., Lai M., Cheung M., Han S., Zhang T., Luo Z., Ting J.W.M., Wong P.W.L., Chan K.Y., So K.F. and Tipoe G.L., Developing local association network based IoT solutions for body parts tagging and tracking, 42 International Journal of Systems and Service-Oriented Engineering. 2010, 1(4): 42-64. |
| Researcher : Tipoe GL |
| Project Title: | Voluntary Oral Feeding of Rats Not Requiring a Very High Fat Diet is a Clinically Relevant Animal Model of Non-Alcoholic Fatty Liver Disease (NAFLD) |
| Investigator(s): | Tipoe GL |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Completion Date: | 12/2010 |
| Project Title: | Green Tea Polyphenols Attenuates the severity of oxidative stress and inflammation in Non-Alcoholic Liver Disease (NAFLD) in Rats |
| Investigator(s): | Tipoe GL |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2010 |
| Project Title: | Thromboxane inhibitors reverse the inflammatory and fibrotic changes in rat liver despite continued ethanol administration. |
| Investigator(s): | Tipoe GL |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| List of Research Outputs |
| Huen M.S.Y., Sy S.M.H., Leung K.M., Ching Y.P., Tipoe G.L., Man C., Dong S. and Chen J., SON is a spliceosome-associated factor required for mitotic progression, CELL CYCLE. 2010, 9(13): 2679-2685. |
| Leung T.M., Fung M.L., Liong E.C., Lau T.Y.H., Nanji A.A. and Tipoe G.L., Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice, Histology and Histopathology. 2011, 26: 201-211. |
| Luo Z., Lai M., Cheung M., Han S., Zhang T., Luo Z., Ting J.W.M., Wong P.W.L., Chan K.Y., So K.F. and Tipoe G.L., Developing local association network based IoT solutions for body parts tagging and tracking, 42 International Journal of Systems and Service-Oriented Engineering. 2010, 1(4): 42-64. |
| Ng K.T., Li J., Ng K.M., Tipoe G.L., Leung W.K. and Fung M.L., Expression of hypoxia-inducible factor-1a in human periodontal tissue, Journal of Periodontology. 2011, 82: 136-141. |
| Wong W.I.N.G. .T.A.K., Tian X.I.A.O. .Y.U., Chen Y.A.N.G.C.H.A.O., Leung F.U.N.G. .P.I.N.G., Liu L.I.M.E.I., Lee H.U.N.G. .K.A.Y., Ng C.H.I. .F.A.I., Xu A., Yao X.I.A.O.Q.I.A.N.G., Vanhoutte P.M.G.R., Tipoe G.L. and Huang Y.U., Bone Morphogenic Protein-4 Impairs Endothelial Function Through Oxidative Stress-Dependent Cyclooxygenase-2 Upregulation Implications on Hypertension, Circulation Research. 2010, 107: 984-991. |
| Wong W.T., Tian X.Y., Chen Y., Leung F.P., Liu L., Lee H.K., Ng C.F., Xu A., Yao X., Vanhoutte P.M.G.R., Tipoe G.L. and Huang Y., Bone morphogenic protein-4 impairs endothelial function through oxidative stress dependent cyclooxygenase-2 upregulation: Iplications on hypertension, Circulation Research. 2010, 107: 984-991. |
| Researcher : Tsang C.M. |
| Project Title: | Investigating the role of Epstein-Barr virus (EBV) in the development of nasopharyngeal carcinoma (NPC): regulation of survivin by EBV encoded latent membrane protein (LMP)1 under starvation stress |
| Investigator(s): | Tsang CM, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2009 |
| Completion Date: | 03/2011 |
| Project Title: | 14th Biennial Conference of the international association for research on Epstein-Barr virus and associated diseases EBV infection suppressed starvation-induced apoptosis in nasopharyngeal epithelial cells |
| Investigator(s): | Tsang CM |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 09/2010 |
| Completion Date: | 09/2010 |
| List of Research Outputs |
| Deng W..., Tsao G...S...W..., Mak W...Y...G..., Tsang C...M..., Ching Y...P..., Guan X..., Huen M...S...Y... and Cheung A..., Impact of G2 checkpoint defect on centromeric instability, Oncogene. 2011, 30: 1281-1289. |
| Researcher : Tsang CM |
| Project Title: | Investigating the role of Epstein-Barr virus (EBV) in the development of nasopharyngeal carcinoma (NPC): regulation of survivin by EBV encoded latent membrane protein (LMP)1 under starvation stress |
| Investigator(s): | Tsang CM, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2009 |
| Completion Date: | 03/2011 |
| Project Title: | 14th Biennial Conference of the international association for research on Epstein-Barr virus and associated diseases EBV infection suppressed starvation-induced apoptosis in nasopharyngeal epithelial cells |
| Investigator(s): | Tsang CM |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 09/2010 |
| Completion Date: | 09/2010 |
| List of Research Outputs |
| Hau P.M., Tsang C.M., Yip Y.L., Huen M.S.Y. and Tsao G.S.W., Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells, PLoS ONE. PLoS ONE, 2011. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and mediates enhanced apoptosis through activation of caspase-dependent pathway., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and medicates enhanced apoptosis through activation of caspase-dependent pathway., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010 (oral presentation). 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid mediates enhanced apoptosis in nasopharyngeal carcinoma through induction of Epstein-Barr virus lytic cycle and activation of caspase-3., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Lui V.W.Y., Yau D.M.S., Cheung C.S.F., Wong S.C.C., Chan A.K.C., Zhou O., Wong E.Y.L., Lau C.P.Y., Lam E.K.Y., Hui E.P., Hong B., Hui C.W.C., Chan A.S.K., Ng P.K.S., Ng Y.K., Lo K.W., Tsang C.M., Tsui S.K.W., Tsao G.S.W. and Chan A.T.C., FGF8b oncogene mediates proliferation and invasion of Epstin-Barr virus-associated nasopharyngeal carcinoma cells: implication for viral-mediated FGF8B upregulation, Oncogene. 2011, 30: 1518-1530. |
| Lui V.W.Y., Wong E.Y.L., Ho K., Ng P.K.S., Lau C.P.Y., Tsui S.K.W., Tsang C.M., Tsao G.S.W., Cheng S.H., Ng M.H.L., Ng Y.K., Lam E.K.Y., Hong B., Lo K.W., Mok T.S.K., Chan A.T.C. and Mills G.B., Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death, Oncogene. 2011, 30: 1127-1134. |
| Ng Y.K., Wong E.Y.L., Lau C.P.Y., Chan J.P.L., Wong S.C.C., Chan A.S.K., Kwan M.P.C., Tsao G.S.W., Tsang C.M., Lai P.B.S., Chan A.T.C. and Lui V.W.Y., K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma cells, Invest New Drugs. 2010, in press. |
| Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, J Cell Biochem. 2010. |
| Wang N., Feng Y., Lau E.P.W., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W.W. and Tsao G.S.W., F-actin reorganization and inactivation of Rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration, Integrative Cancer Therapies. USA, SAGE, 2010. |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Researcher : Tsang CM |
| List of Research Outputs |
| Hau P.M., Tsang C.M., Yip Y.L., Huen M.S.Y. and Tsao G.S.W., Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells, PLoS ONE. PLoS ONE, 2011. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and mediates enhanced apoptosis through activation of caspase-dependent pathway., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and medicates enhanced apoptosis through activation of caspase-dependent pathway., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010 (oral presentation). 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid mediates enhanced apoptosis in nasopharyngeal carcinoma through induction of Epstein-Barr virus lytic cycle and activation of caspase-3., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Lui V.W.Y., Yau D.M.S., Cheung C.S.F., Wong S.C.C., Chan A.K.C., Zhou O., Wong E.Y.L., Lau C.P.Y., Lam E.K.Y., Hui E.P., Hong B., Hui C.W.C., Chan A.S.K., Ng P.K.S., Ng Y.K., Lo K.W., Tsang C.M., Tsui S.K.W., Tsao G.S.W. and Chan A.T.C., FGF8b oncogene mediates proliferation and invasion of Epstin-Barr virus-associated nasopharyngeal carcinoma cells: implication for viral-mediated FGF8B upregulation, Oncogene. 2011, 30: 1518-1530. |
| Lui V.W.Y., Wong E.Y.L., Ho K., Ng P.K.S., Lau C.P.Y., Tsui S.K.W., Tsang C.M., Tsao G.S.W., Cheng S.H., Ng M.H.L., Ng Y.K., Lam E.K.Y., Hong B., Lo K.W., Mok T.S.K., Chan A.T.C. and Mills G.B., Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death, Oncogene. 2011, 30: 1127-1134. |
| Ng Y.K., Wong E.Y.L., Lau C.P.Y., Chan J.P.L., Wong S.C.C., Chan A.S.K., Kwan M.P.C., Tsao G.S.W., Tsang C.M., Lai P.B.S., Chan A.T.C. and Lui V.W.Y., K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma cells, Invest New Drugs. 2010, in press. |
| Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, J Cell Biochem. 2010. |
| Wang N., Feng Y., Lau E.P.W., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W.W. and Tsao G.S.W., F-actin reorganization and inactivation of Rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration, Integrative Cancer Therapies. USA, SAGE, 2010. |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Researcher : Tsao G.S.W. |
| Project Title: | Mechansims involved in the induction of chromosome instability by the Epstein Barr virus encoded LMP1 protein. |
| Investigator(s): | Tsao GSW, Cheung A, Chow BKC, Lo KW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2007 |
| Completion Date: | 03/2011 |
| Project Title: | Cancer |
| Investigator(s): | Tsao GSW, Poon RTP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2008 |
| Completion Date: | 10/2011 |
| Project Title: | Cancer |
| Investigator(s): | Tsao GSW, Poon RTP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2008 |
| Project Title: | The role of TGF-beta in EBV infection and pathogenesis of nasopharyngeal carcinoma |
| Investigator(s): | Tsao GSW, Lan HY |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Project Title: | The role of STAT activation in regulating persistence of EBV infection in premalignant nasopharyngeal epithelial cell model |
| Investigator(s): | Tsao GSW, Chen H, Lo KW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | The impact of Bmi-1 expression on mitosis and cancer |
| Investigator(s): | Tsao GSW, Zeng M |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2009 |
| Project Title: | Regulation of Epstein-Barr virus infection in nasopharyngeal epithelial cells |
| Investigator(s): | Tsao GSW, Chen H |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2010 |
| Project Title: | NF-kB activation in the immortalization of nasopharyngeal epithelial cells |
| Investigator(s): | Tsao GSW, Lo KW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2010 |
| Project Title: | The role of EGFR in immortalization and malignant transformation of nasopharyngeal epithelial cells |
| Investigator(s): | Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2011 |
| Project Title: | American Association for Cancer Research 102nd Annual Meeting 2011 EBV infection of immortalized nasopharyngeal epithelial cells confers sensitivity to IL6-induced activation of STAT3 |
| Investigator(s): | Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 04/2011 |
| Completion Date: | 04/2011 |
| List of Research Outputs |
| Deng W..., Tsao G...S...W..., Mak W...Y...G..., Tsang C...M..., Ching Y...P..., Guan X..., Huen M...S...Y... and Cheung A..., Impact of G2 checkpoint defect on centromeric instability, Oncogene. 2011, 30: 1281-1289. |
| Researcher : Tsao GSW |
| Project Title: | Mechansims involved in the induction of chromosome instability by the Epstein Barr virus encoded LMP1 protein. |
| Investigator(s): | Tsao GSW, Cheung A, Chow BKC, Lo KW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2007 |
| Completion Date: | 03/2011 |
| Project Title: | Cancer |
| Investigator(s): | Tsao GSW, Poon RTP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2008 |
| Completion Date: | 10/2011 |
| Project Title: | Cancer |
| Investigator(s): | Tsao GSW, Poon RTP |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2008 |
| Project Title: | The role of TGF-beta in EBV infection and pathogenesis of nasopharyngeal carcinoma |
| Investigator(s): | Tsao GSW, Lan HY |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Project Title: | The role of STAT activation in regulating persistence of EBV infection in premalignant nasopharyngeal epithelial cell model |
| Investigator(s): | Tsao GSW, Chen H, Lo KW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Project Title: | The impact of Bmi-1 expression on mitosis and cancer |
| Investigator(s): | Tsao GSW, Zeng M |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2009 |
| Project Title: | Regulation of Epstein-Barr virus infection in nasopharyngeal epithelial cells |
| Investigator(s): | Tsao GSW, Chen H |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2010 |
| Project Title: | NF-kB activation in the immortalization of nasopharyngeal epithelial cells |
| Investigator(s): | Tsao GSW, Lo KW |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2010 |
| Project Title: | The role of EGFR in immortalization and malignant transformation of nasopharyngeal epithelial cells |
| Investigator(s): | Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2011 |
| Project Title: | American Association for Cancer Research 102nd Annual Meeting 2011 EBV infection of immortalized nasopharyngeal epithelial cells confers sensitivity to IL6-induced activation of STAT3 |
| Investigator(s): | Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 04/2011 |
| Completion Date: | 04/2011 |
| List of Research Outputs |
| Chan K.C., Ko J.M.Y., Lung H.L., Sedlacek R., Zhang Z.F., Luo D.Z., Feng Z.B., Chen S., Chen H., Chan K.W., Tsao G.S.W., Chua D.T.T., Zabarovsky E.R., Stanbridge E.J. and Lung M.L., Catalytic activity of matrix metalloproteinase-19 is essential for tumor suppressor and anti-angiogenic activities in nasopharyngeal carcinoma, International Journal of Cancer. 2010. |
| Chan S.H.K., Ko J.M.Y., Chan K.W., Chan Y.P., Tao Q., Hyytiainen M., Keski-Oja J., Law S.Y.K., Srivastava G., Tang J., Tsao G.S.W., Chen H., Stanbridge E.J. and Lung M.L., The ECM portein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome, International Journal of Cancer. 2011, 129: 565-573. |
| Cheung A., Li B., Chan K.W. and Tsao G.S.W., IGF1R-targeting as potential immunotherapy for esophageal cancer, 2nd International Cancer Immunotherapy and Immujomonitoring Conference, May 2-5, Budapest, Hungary. 2011, 70. |
| Cheung A.K.L., Ko J.M.Y., Lung H.L., Chan K.W., Stanbridge E.J., Zabarovsky E.R., Kwong D.L.W., Chua D.T.T., Tsao G.S.W. and Lung M.L., CRIP2 is a candidate tumor suppressor in nasopharyngeal carcinoma associated with in vivo tumor suppression and angiogenesis inhibition., The 17th Hong Kong International Cancer Congress. Hong Kong SAR, China, 2010. |
| Cheung A.K.L., Ko J.M.Y., Lung H.L., Chan K.W., Stanbridge E.J., Zabarovsky E., Tokino T., Kashima L., Suzuki T., Kwong D.L.W., Chua D.T.T., Tsao G.S.W. and Lung M.L., Cysteine-rich intestinal protein 2 (CRIP2) acts as a repressor of NF-kB-mediated proangiogenic cytokine transcription to suppress tumorigenesis and angiogenesis, PNAS. 2011, 108(20): 8390-8395. |
| Cheung A.K.L., Ko J.M.Y., Lung H.L., Stanbridge E.J., Zabarovsky E.R., Kwong D.L.W., Chua D., Tsao G.S.W. and Lung M.L., Functional investigation of tumor and angiogenesis suppressive candidate tumor suppressor, Cysteine-rich intestinal protein 2 in nasopharyngeal carcinoma, The 14th Biennial Symposium of the International Association for Research on Epstein-Barr Virus and Associated Diseases. Birmingham, UK, 2010. |
| Cheung P.P.Y., Deng W., Man C.W.Y., Tse W.W., Srivastava G., Law S.Y.K., Tsao G.S.W. and Cheung A., Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: Implications for carcinogenesis, Cancer Letters. 2010, 293(1): 41-51. |
| Cheung P.Y., Yip Y.L., Tsao G.S.W., Ching Y.P. and Cheung A., Id-1 induces cell invasiveness in immortalized epithelial cells by regulating cadherin switching and Rho GTPases, Journal of Cellular Biochemistry. 2011, 112: 157-168. |
| Feng Y., Wang N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on anti-cancer and anti-liver fibrosis between bear bile and botanic Chinese medicines, 2010 international conference on integrate medicine against cancer cum 6th Pong Ding Yuen international symposium on traditional Chinese Medicine. 2010. |
| Feng Y., Wang N., Zhu M., Zhang Z.J., Tong Y. and Tsao G.S.W., Interdisciplinary approaches in study of Chinese medicines: case of coptis, 15th World Congress on Advances in Oncology and 13th International Symposium on Molecular Medicine. 2010. |
| Feng Y., Wang N., Zhu M., Tsao G.S.W., Feng Y.G. and Li H.Y., Recent progress on anticancer candidates in herbal medicinal products. Recent patent in Food, Nutrition & Agriculture. , Recent patent in Food, Nutrition & Agriculture. 2011. |
| Hau P.M., Tsang C.M., Yip Y.L., Huen M.S.Y. and Tsao G.S.W., Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells, PLoS ONE. PLoS ONE, 2011. |
| Hong B., Lui V.W.Y., Hui E.P., Ng M.H.L., Cheng S.H., Sung F.L., Tang C.M., Tsao G.S.W. and Chan A.T.C., Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation, Invest New Drugs. 2011, 29: 401-410. |
| Hui F.F., Chan W.Y., Fung K.H.Y., Yu C.L., Tsao G.S.W., Chan M.C.W. and Nicholls J.M., The regional distribution of different types of influenza receptors in cultured human alveolar epithelial cells and correlation with in vitro infection, Influenza and other respiratory viruses. 2011, 5(S1): 436-437. |
| Hui F.F., Chan W.Y., Fung K.H.Y., Yu C.L., Tsao G.S.W., Chan M.C.W. and Nicholls J.M., The regional distribution of different types of influenza receptors in cultured human alveolar epithelial cells and correlation with in vitro infection, Influenza and other respiratory viruses. 2011, 5(S1): 436-437. |
| Hui F.F., Chan W.Y., Fung K.H.Y., Yu C.L., Tsao G.S.W., Chan M.C.W. and Nicholls J.M., The regional distribution of different types of influenza receptors in cultured human alveolar epithelial cells and correlation with in vitro infection, Options for the Control of Influenza VII. 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and mediates enhanced apoptosis through activation of caspase-dependent pathway., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and medicates enhanced apoptosis through activation of caspase-dependent pathway., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010 (oral presentation). 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid mediates enhanced apoptosis in nasopharyngeal carcinoma through induction of Epstein-Barr virus lytic cycle and activation of caspase-3., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Lam C.L.D., Fu K.H., Lui M.M.S., Yung P.M., Cheung A.H.K., Lam W.K., Wistuba I.I., Tsao G.S.W., Ip M.S.M. and Minna J.D., Expression of nicotinic acetylcholine receptor in human bronchial epithelium in relation to airflow obstruction, American Thoracic Society Annual Meeting 2011. |
| Li G., Lee L.S., Li M., Tsao G.S.W. and Chiu J., Molecular changes during arsenic-induced cell transformation, Journal of Cellular Physiology. 2011, in press. |
| Li J., Li B., Tsao G.S.W. and Cheung A., Role of AMPK-mTOR signaling in anticancer effects of silibinin on esophageal squamous cell carcinoma, Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research, April 2-6, 2011 U.S.A.. 2011. |
| Lo H.Y.P., Lung H.L., Cheung A.K.L., Apte S.S., Chan K.W., Kwong F.M., Ko J.M.Y., Cheng Y., Law S.Y.K., Srivastava G., Zabarovsky E.R., Tsao G.S.W., Tang J.C., Stanbridge E.J. and Lung M.L., Extracellular protease ADAMTS9 suppresses esophageal and nasopharyngeal carcinoma tumor formation by inhibiting angiogenesis, Cancer Res. 2010, 70(13): 5567-76. |
| Lui V.W.Y., Yau D.M.S., Cheung C.S.F., Wong S.C.C., Chan A.K.C., Zhou O., Wong E.Y.L., Lau C.P.Y., Lam E.K.Y., Hui E.P., Hong B., Hui C.W.C., Chan A.S.K., Ng P.K.S., Ng Y.K., Lo K.W., Tsang C.M., Tsui S.K.W., Tsao G.S.W. and Chan A.T.C., FGF8b oncogene mediates proliferation and invasion of Epstin-Barr virus-associated nasopharyngeal carcinoma cells: implication for viral-mediated FGF8B upregulation, Oncogene. 2011, 30: 1518-1530. |
| Lui V.W.Y., Wong E.Y.L., Ho K., Ng P.K.S., Lau C.P.Y., Tsui S.K.W., Tsang C.M., Tsao G.S.W., Cheng S.H., Ng M.H.L., Ng Y.K., Lam E.K.Y., Hong B., Lo K.W., Mok T.S.K., Chan A.T.C. and Mills G.B., Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death, Oncogene. 2011, 30: 1127-1134. |
| Lung H.L., Cheung A.K.L., Cheng Y., Kwong F.M., Lo P.H.Y., Law E.W., Chua D.T.T., Zabarovsky E.R., Wang N., Tsao G.S.W., Stanbridge E.J. and Lung M.L., Functional characterization of THY1 as a tumor suppressor gene with antiinvasive activity in nasopharyngeal carcinoma, International journal of cancer. . 2010, 127(2): 304-12. |
| Ng Y.K., Wong E.Y.L., Lau C.P.Y., Chan J.P.L., Wong S.C.C., Chan A.S.K., Kwan M.P.C., Tsao G.S.W., Tsang C.M., Lai P.B.S., Chan A.T.C. and Lui V.W.Y., K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma cells, Invest New Drugs. 2010, in press. |
| Siu K.Y., Chan H.Y., Kong S.H., Wong E.S.Y., Wong G.W., Ngan H.Y.S., Tam K.F., Tsao G.S.W. and Cheung A.N.Y., p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients., Proceedings of the National Academy of Sciences of the United States of America . 2010, 107: 18622-18627. |
| Siu K.Y., Chan H.Y., Kong S.H., Wong S.Y., Wong G.W., Ngan H.Y.S., Tam K.F., Zhang H., Li Z., Chan Q.K.Y., Tsao G.S.W., Strömblad S. and Cheung A.N.Y., p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients, PNAS. 2010, 107(43): 18622-18627. |
| Tsao G.S.W., Application of live cell imaging in mitosis, Hong Kong Society of Cytogenetics. 2010. |
| Tsao G.S.W., Current Cancer Drug Targets. 2010. |
| Tsao G.S.W., EBV infection in nasopharyngeal epithelial cells, Shantou University, Medical School. 2010. |
| Tsao G.S.W., EBV infection in premalignant nasopharyngeal epithelial cell models, Seminar in Cancer Biology. 2011. |
| Tsao G.S.W., Inflammation, microenvironment and cancer, Public Lecture Series, organized by the Faculty of Medicine, University of Hong Kong. 2010. |
| Tsao G.S.W., Journal of Molecular Imaging & Dynamics , 2010. |
| Tsao G.S.W., • Cyclin D1 facilitates stable and latent infection of EBV in nasopharyngeal epithelial cell. The 5th International Symposium on Nasopharyngeal Carcinoma. Penang, Malaysia. June 22-24, 2011., 2011. |
| Tsao G.S.W., • Regulation of EBV infection in nasopharyngeal epithelial cells. McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, USA. April 8th, 2011. |
| Tsao G.S.W., • Tumour microenvironment, a target for Traditional Chinese Medicine? Plenary Speaker; 2010 International Conference on Integrative Medicine against Cancer cum The 6th Pong Ding Yuen International symposium on Traditional Chinese Medicine (2010 中西醫結合防治腫瘤國際會議暨第六屆龐鼎元國際中醫藥研討會). Hong Kong. November 26-27, , 2010. |
| Wang N., Zhu M., Feng Y., Tong Y. and Tsao G.S.W., 3alpha,7beta-Dihydroxy-5beta-cholan -24-oic Acid N-(2-Sulfoethyl)amide alters the microRNAs expression and promotes cell migration of human hepatocellular carcinoma cells, International Journal of Cancer (Excellence in Oncology, 18-20 November 2010, Athens, Hilton, Greece). 2010. |
| Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, J Cell Biochem. 2010. |
| Wang N., Feng Y., Lau E.P.W., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W.W. and Tsao G.S.W., F-actin reorganization and inactivation of Rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration, Integrative Cancer Therapies. USA, SAGE, 2010. |
| Wang N., Zhu M., Feng Y., Tong Y. and Tsao G.S.W., Tumor necrosis factor-α up-regulates the microRNA-21 expression and promotes cell migration in human hepatocellular carcinoma cells MHCC97-L, International Journal of Cancer (Excellence in Oncology, 18-20 November 2010, Athens, Hilton, Greece),. 2010. |
| Wong T.S., Chan W.S., Li C.H., Liu R.W., Tang W.W., Tsao G.S.W., Tsang R.K.Y., Ho W.K., Wei W.I. and Chan J.Y.K., Curcumin alters the migratory phenotype of nasopharyngeal carcinoma cells through up-egulation of E-cadherin, Anticancer Research. 2010, 30(7): 2851-2856. |
| Wong V.C., Chen H., Ko J.M.Y., Chan K.W., Chan Y.P., Law S.Y.K., Chua D.T.T., Kwong D.L.W., Lung H.L., Srivastava G., Tang J.C., Tsao G.S.W., Zabarovsky E.R., Stanbridge E.J. and Lung M.L., Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype, International journal of cancer. . 2011. |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Zhu M., Wang N., Tsao G.S.W., Yuen R.M.F., Feng Y.G., Wan T.S.K., Man K. and Feng Y., Up-regulation of microRNAs, miR21 and miR23a, in human liver cancer cells treated with Coptidis Rhizome aqueous extract, Experimental and Therapeutic Medicine. 2011. |
| Researcher : Tse WW |
| List of Research Outputs |
| Cheung P.P.Y., Deng W., Man C.W.Y., Tse W.W., Srivastava G., Law S.Y.K., Tsao G.S.W. and Cheung A., Genetic alterations in a telomerase-immortalized human esophageal epithelial cell line: Implications for carcinogenesis, Cancer Letters. 2010, 293(1): 41-51. |
| Researcher : Wang X |
| Project Title: | The role fo MAD2 in overcoming cisplatin resistance in testicular germ cell tumors |
| Investigator(s): | Wang X, Jin D |
| Department: | Anatomy |
| Source(s) of Funding: | Lance Armstrong Foundation - General Award |
| Start Date: | 10/2003 |
| Project Title: | Significance of MAD2 expression to chromosomal instability in prostate cancer |
| Investigator(s): | Wang X, Jin D Y |
| Department: | Anatomy |
| Source(s) of Funding: | Association for International Cancer Research - General Award |
| Start Date: | 04/2004 |
| Project Title: | Molecular mechanisms involved in the suppressive effects of garlic derivatives on cell growth and motility in prostate cancer cells |
| Investigator(s): | Wang X, Jin D Y |
| Department: | Anatomy |
| Source(s) of Funding: | American Institute for Cancer Research (AICR) - General Award |
| Start Date: | 08/2005 |
| List of Research Outputs |
| Chua C.W., Chiu Y.T., Yuen H.F., Chan K.W., Wang X., Ling M.T. and Wong Y.C., Differential expression of MSX2 in nodular hyperplasia, high-grade prostatic intraepithelial neoplasia and prostate adenocarcinoma, APMIS. 2010, 118(12): 918-26. |
| Researcher : Wang X |
| Project Title: | Angio-(1-7) and ACE2 during normal and hypertensive pregnancy |
| Investigator(s): | Wang X, Ellis-Behnke RG |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2008 |
| Researcher : Wong PWL |
| List of Research Outputs |
| Luo Z., Lai M., Cheung M., Han S., Zhang T., Luo Z., Ting J.W.M., Wong P.W.L., Chan K.Y., So K.F. and Tipoe G.L., Developing local association network based IoT solutions for body parts tagging and tracking, 42 International Journal of Systems and Service-Oriented Engineering. 2010, 1(4): 42-64. |
| Researcher : Wong YC |
| Project Title: | Induction of breast carcinogenesis by a combination of androgens and oestrogens |
| Investigator(s): | Wong YC, Xie B |
| Department: | Anatomy |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/1997 |
| Project Title: | The Beijing, Hong Kong and UK Collaborative Study on the Molecular Genetic Basis of Differential Susceptibility of Prostate Cancer Between Chinese and Caucasian |
| Investigator(s): | Wong YC, Wang X, Ho KMT |
| Department: | Anatomy |
| Source(s) of Funding: | The University of Hong Kong Foundation Seed Grant |
| Start Date: | 07/2003 |
| List of Research Outputs |
| Chua C.W., Chiu Y.T., Yuen H.F., Chan K.W., Wang X., Ling M.T. and Wong Y.C., Differential expression of MSX2 in nodular hyperplasia, high-grade prostatic intraepithelial neoplasia and prostate adenocarcinoma, APMIS. 2010, 118(12): 918-26. |
| Luk S.U., Lee K.W., Liu J.I., Lee D.T.W., Chiu Y.T., Ma S.K.Y., Ng I.O.L., Wong Y.C., Chan F.L. and Ling M.T., Chemopreventive effect of PSP through targeting of prostate cancer stem cell-like population, PLoS One. 2011, 6: e19804. |
| Researcher : Wong YN |
| List of Research Outputs |
| Wong Y.N., The potential applications of AMPK acgivator resveratrol and PAK1 inhibitor IPA-3 in cancer therapy. 2010, 111 pages. |
| Researcher : Wu EX |
| Project Title: | Magnetic resonance imaging for biomedical research |
| Investigator(s): | Wu EX |
| Department: | Engineering Faculty |
| Source(s) of Funding: | Seed Funding for New Staff |
| Start Date: | 02/2004 |
| Project Title: | Magnetic Resonance Measurement of Heart and Liver Iron |
| Investigator(s): | Wu EX |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | The National Institute of Diabetes and Digestive and Kidney Diseases |
| Start Date: | 11/2006 |
| Project Title: | Thalassaemia Major: A new MRI method for monitoring heart and liver iron deposition |
| Investigator(s): | Wu EX, Au WY, Ha SY |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 09/2007 |
| Project Title: | Thalassaemia major: a new MRI method for detection and monitoring of heart and liver iron deposition |
| Investigator(s): | Wu EX, Ha SY, Khong PL, Tse HF |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2007 |
| Completion Date: | 02/2011 |
| Project Title: | MR Study of High-order Water Molecule Diffusion in Biological Systems |
| Investigator(s): | Wu EX |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2007 |
| Completion Date: | 11/2010 |
| Project Title: | Manganese-enhanced MRI for In Vivo Detection of Neurodegeneration in Neonatal Hypoxic-ischemic Brain Injury |
| Investigator(s): | Wu EX, Khong PL |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2008 |
| Completion Date: | 02/2011 |
| Project Title: | Neuroimaging of Spontaneous Brain Activities in Anaesthetized Rodents |
| Investigator(s): | Wu EX |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2008 |
| Completion Date: | 10/2010 |
| Project Title: | Diffusion Kurtosis Imaging For Improved Neural Tissue Characterization By Magnetic Resonance |
| Investigator(s): | Wu EX, Khong PL, Wu W |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2009 |
| Project Title: | In Vivo MRI of Endogenous Stem/Progenitor Cell Migration in Developing Brains |
| Investigator(s): | Wu EX |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2009 |
| Completion Date: | 10/2011 |
| Project Title: | MRI Investigation of Left Ventricular Structure and Function |
| Investigator(s): | Wu EX, Chow KW, Tse HF |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2010 |
| Project Title: | Outstanding Researcher Award 2009-10 |
| Investigator(s): | Wu EX |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | Outstanding Researcher Award |
| Start Date: | 12/2010 |
| Project Title: | RETINOTOPIC MAPPING OF SUPERIOR COLLICULUS USING MEMRI |
| Investigator(s): | Wu EX |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2011 |
| Project Title: | 19th Annual Meeting of International Society of Magnetic Resonance in Medicine (ISMRM) Molecular MRI of Liver Fibrosis by Fibrin-Fibronectin Targeted Contrast Agent in an Experimental Mouse Model |
| Investigator(s): | Wu EX |
| Department: | Electrical & Electronic Engg |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Cheung S.C., Fan S., Gao D.S., Chow A.M.K., Yang J., Man K. and Wu E.X., In vivo lipid profiling using proton magnetic resonance spectroscopy in an experimental liver fibrosis model, Academic Radiology. 2011, 18(3): 377-383. |
| Researcher : Wu W |
| Project Title: | Effects of chondroitinase ABC and lithium chloride on neuronal survival and regeneration after spinal cord injury |
| Investigator(s): | Wu W, Yick LW, So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Matching Fund for National Key Basic Research Development Scheme (973 Projects) |
| Start Date: | 11/2003 |
| Project Title: | Remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis by transplantation of oligodendrocyte precursor cells |
| Investigator(s): | Wu W |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2008 |
| Completion Date: | 11/2010 |
| Project Title: | Research Output Prize |
| Investigator(s): | Wu W, Su H, Wong WM, So KF, Wu EX |
| Department: | Anatomy |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 10/2008 |
| Project Title: | Implantation of trophic factor-treated sensory nerve graft for motoneuron regeneration after spinal root avulsion injuries |
| Investigator(s): | Wu W |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2009 |
| Completion Date: | 06/2011 |
| Project Title: | Effects and mechanisms of fingolimod on oligodendrocyte maturation and remyelination in animals with experimental autoimmune encephalomyelitis |
| Investigator(s): | Wu W |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2010 |
| Project Title: | Bridge the gap in nerve tissue injury to promote axonal regeneration with self-assembling peptide nanofibre scaffold (SAPNS) |
| Investigator(s): | Wu W |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Leung C., Chan S.C.L., Tsang S.L., Wu W. and Sham M.H., Differential regulation of retinoic acid signaling in adult spinal cord neural progenitors., 9th Annual International Society of Stem Cell Research Meeting, Toronto, Canada, June 15-18, 2011. |
| Leung G.K.K., Wang Y. and Wu W., An animal study comparing electrocoagulation, fibrin glue, and nanopeptide scaffold in neurosurgical haemostasis. , The 19th Annual Scientific Meeting. The Hong Kong Neurosurgical Society, Hong Kong, December 2010. |
| Leung G.K.K., Guo J. and Wu W., Self-assembling peptide nanofibre scaffold (SAPNS) as a potential neuro-regenerative biomaterial in surgically induced brain injury. (Abstract) , Surgical Practice. 2010, 14: S37. |
| Sang Y., Su H., Yang X., Liu L.G., Wu W. and Cheung R.T.F., Neural stem cell transplantation in a rat model of intracerebral haemorrhage plus haematoma aspiration, Sixteenth Medical Research Conference. 2011, 17 (Suppl 1): 51. |
| Un K.C., Li L.F., Wu W. and Leung G.K.K., Glial reaction of the brain after bipolar coagulation : a pilot study, Surgical Practice (Published abstract). 2010, 14: S49. |
| Yuan Q.J., Hu B., Chu T.H., Su H., Zhang W., So K.F., Lin Z. and Wu W., Co-expression of GAP-43 and nNOS in avulsed motoneurons and their potential role for motoneuron regeneration, Nitric Oxide. 2010, 23: 258-263. |
| Researcher : Xiao Q |
| List of Research Outputs |
| Du Y., Xiao Q. and Yip H.K.F., Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the Smad/Id cascade, Investigative Ophthalmology and Visual Science. Association for Research in Vision and Ophthalmology, 2010, 51: 3764-3773. |
| Researcher : Xu H |
| List of Research Outputs |
| Chan M.L., Xu H. and Ching Y.P., Characterization of PAK4 and RhoV in hepatocellular carcinoma (HCC)., In: European Molecular Biology Organization, The EMBO Meeting 2010 Barcelona Spain . 2010. |
| Researcher : Yan SWL |
| List of Research Outputs |
| Lau W.M., Ren C., Yang J., Yan S.W.L., Chang R.C.C., Pu M. and So K.F., Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal Mongolian gerbil (Meriones unguiculatus), Cell Transplantation. 2011, 20: 871-881. |
| Researcher : Yang D |
| List of Research Outputs |
| Li S.Y., Yang D., Yeung C.M., Yu W.Y., Chang R.C.C., So K.F., Wong D.S.H. and Lo A.C.Y., Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury, PLoS One. 2011, 6(1): e16380. |
| Researcher : Yang J |
| Project Title: | Investigation of physiology and possible neuroprotective effect of the retinal microglia under normal and glaucoma conditions |
| Investigator(s): | Yang J, So KF, Chang RCC |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2008 |
| List of Research Outputs |
| Lau W.M., Ren C., Yang J., Yan S.W.L., Chang R.C.C., Pu M. and So K.F., Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal Mongolian gerbil (Meriones unguiculatus), Cell Transplantation. 2011, 20: 871-881. |
| Luan L., Ren C., Lau W.M., Yang J., Pickard G.E., So K.F. and Pu M., Y-like retinal ganglion cells innervate the dorsal raphe nucleus in the Mongolian gerbils (Meriones unguiculatus), PLoS ONE. 2011, 6(4): e18938. |
| Ren C., Lau W.M., Luan L., Yang J., So K.F. and Pu M., Mongolian gerbil as a seasonal affective disorder animal model, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 140. |
| Researcher : Yang X |
| List of Research Outputs |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17. |
| Sang Y., Su H., Yang X., Liu L.G., Wu W. and Cheung R.T.F., Neural stem cell transplantation in a rat model of intracerebral haemorrhage plus haematoma aspiration, Sixteenth Medical Research Conference. 2011, 17 (Suppl 1): 51. |
| Researcher : Yang X |
| List of Research Outputs |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17. |
| Sang Y., Su H., Yang X., Liu L.G., Wu W. and Cheung R.T.F., Neural stem cell transplantation in a rat model of intracerebral haemorrhage plus haematoma aspiration, Sixteenth Medical Research Conference. 2011, 17 (Suppl 1): 51. |
| Researcher : Yau SY |
| Project Title: | Significance of mTOR signalling pathway in mediating the beneficial effects of physical exercise on hippocampal plasticity in stressed rats |
| Investigator(s): | Yau SY, So KF |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2011 |
| List of Research Outputs |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Effect of corticosterone and paroxetine on masculine mating behavior: Possible involvement of neurogenesis, The Journal of Sexual Medicine. 2011, 8: 1390-1403. |
| Lau W.M., Lee C.D., Yau S.Y., Chang R.C.C. and So K.F., Facilitation of male sexual behavior by lycium barbarum (wolfberry) polysaccharide, The Consortium for Globalizaiton of Chinese Medicine. Aug. 23-25, 2010 Hong Kong. 2010, 106 No. 126. |
| Lau W.M., Yau S.Y., Lee T.M.C., Ching Y.P., Tang S.W. and So K.F., Possible involvement of neurogenesis in male rat mating behavior, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 141. |
| Qiu G., Wan R., Hu J., Mattson M.P., Spangler E., Liu S., Yau S.Y., Lee T.M.C., Gleichmann M., Ingram D.K., So K.F. and Zou S., Adiponectin protects rat hippocampal neurons against excitotoxicity, Age. 2011, 33: 155-165. |
| Tang S.W., So K.F., Helmeste D.M., Lau W.M., Yau S.Y. and Lee T.M.C., Is adult neurogenesis relevant in human depression?, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 142. |
| Yau S.Y., FAONS-APRC Travel Award, Federation of Asian and Oceanian Neuroscience Societies and International Brain Research Organization. 2010. |
| Yau S.Y., FAONS-IBRO Travel Award, Federation of Asian and Oceanian Neuroscience Societies and International Brain Research Society. 2010. |
| Zhang E., Yau S.Y., Lau W.M., Lee T.M.C., Chang R.C.C. and So K.F., Promotion of neurogenesis and preservation of dendrites by wolfberry in experimental depression, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 208. |
| Researcher : Yeung PKK |
| Project Title: | The Effectiveness of Vasopressin V1 receptor antagonist , SR49059, and V2 Receptor Anatongist, OPC-31260, on Cerebral Edema Formation in Endothelin-1-Overexpressed Mice |
| Investigator(s): | Yeung PKK, Chung SK |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2008 |
| List of Research Outputs |
| Cheng L., Yeung P.K.K., Kai A.K.L., Chung S.S.M. and Chung S.K., Role of Epac in the pathogenesis of ischemic stroke, 15th Research Postgraduate Symposium, Dec. 1-2, 2010, The University of Hong Kong, Hong Kong. 2010, 82. |
| Wong A.S.L., Lee R.H.K., Cheung A.Y., Yeung P.K.K., Chung S.K., Cheung Z.H. and Ip N.Y., Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease, Nature cell Biology. 2011, 13(5): 568-579. |
| Yeung P.K.K., Lai K.W., Son H.J., Zhang X., Hwang O., Chung S.S.M. and Chung S.K., Aldose reductase-deficiency leads to more significant loss of dopaminergeric neurons with incresed levels of dopamine, tetrahydrobiopterin and free radical accumulation under experimental Parkinson's Disease condition, Society for Neuroscience 2010. |
| Researcher : Yeung SC |
| List of Research Outputs |
| Chiu K., Yeung S.C., Lok C.K.M., Zhou Y., Chang R.C.C. and So K.F., Neuroimmune responses of polysacharides from lycium barbarum (wolfberry) in retina after experimental glaucoma, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010 Hong Kong. 2010, 102 No.121. |
| Researcher : Yip HKF |
| Project Title: | In vivo gene transfer of the catalytic subunit of telomerase protects retinal ganglion cells against axotomy-induced cell death |
| Investigator(s): | Yip HKF, Tsao GSW, Chung SK |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2005 |
| Project Title: | Interactions between inhibitors of DNA binding (Id) and bone morphogenetic proteins (BMPs) in retinal cell specification |
| Investigator(s): | Yip HKF, Sham MH, Wong YC |
| Department: | Anatomy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2008 |
| Completion Date: | 02/2011 |
| Project Title: | Telomerase immortalization of retinal ganglion cells derived from the embryonic mouse retinal progenitor cells |
| Investigator(s): | Yip HKF, Tsao GSW |
| Department: | Anatomy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Project Title: | Telomerase acts downstream of brain-derived neurotrophic factor signaling in neural progenitor cells isolated from the aged mouse brain |
| Investigator(s): | Yip HKF, Tsao GSW, Zhou Z |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2010 |
| Completion Date: | 09/2011 |
| Project Title: | Combined treatment of lithium and noggin inhibits astroglios after spinal cord injury by deactivation of GSK-3β/STAT3 are BMP/Smad pathways in the endogenous adult neural stem cells |
| Investigator(s): | Yip HKF, Shum DKY |
| Department: | Anatomy |
| Source(s) of Funding: | Spinal Cord Injury Research Grant |
| Start Date: | 05/2010 |
| Project Title: | The 40th Annual Meeting of Society for Neuroscience (Neuroscience 2010) The Neuroprotective signaling mechanisms of telomerase via the induction by brain-derived neurotrophic factor in rat spinal cord motor neurons |
| Investigator(s): | Yip HKF |
| Department: | Anatomy |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 11/2010 |
| Completion Date: | 11/2010 |
| Project Title: | Directed differentiation of human embryonic stem cell-derived retinal progenitors into retinal ganglion cells by BMP4 in vitro. |
| Investigator(s): | Yip HKF |
| Department: | Anatomy |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2011 |
| List of Research Outputs |
| Du Y., Xiao Q. and Yip H.K.F., Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the Smad/Id cascade, Investigative Ophthalmology and Visual Science. Association for Research in Vision and Ophthalmology, 2010, 51: 3764-3773. |
| Du Y. and Yip H.K.F., The expression of roles of inhibitor of DNA binding helix-loop-helix proteins in the developing and adult mouse retina. , Neuroscience. Elsevier, 2011, 175: 367-379. |
| Niu C. and Yip H.K.F., The neuroprotective signaling mechanisms of telomerase via the induction by brain-derived neurotrophic factor in rat spinal cord motor neurons, Society of Neuroscience Annual Meeting, November 2010. Program No. 470.13: Poster No. FF6. |
| Niu C. and Yip H.K.F., The neuroprotective signaling mechanisms of telomerase via the induction by brain-derived neurotrophic factor in rat spinal cord motor neurons, USA Society of Neuroscience Annual Meeting. 2010. |
| Yip H.K.F., Continuing Professional Development Grant, The University of Hong Kong. 2011. |
| Yip H.K.F. and Liu M., Id2 expression profile and potential role in the regulation of neural stem cells in the subventriclar zone of adult mouse brain, Adult Neurogenesis. 2011, 89 Poster No. 325. |
| Yip H.K.F. and Liu M., The expression of Id2 and its potential roles in the regulation of neural stem/progenitor cells in the subventricular zone of adult mouse brain, Keystone Symposia on Molecular and Cellular Biology, Adult Neurogenesis, Taos, New Mexico, USA. 2011. |
| Yip H.K.F., University of Hong Kong/China Medical Board Grants 2010/2011, The University of Hong Kong/China Medical Board. 2011. |
| Researcher : Yip YL |
| List of Research Outputs |
| Cheung P.Y., Yip Y.L., Tsao G.S.W., Ching Y.P. and Cheung A., Id-1 induces cell invasiveness in immortalized epithelial cells by regulating cadherin switching and Rho GTPases, Journal of Cellular Biochemistry. 2011, 112: 157-168. |
| Hau P.M., Tsang C.M., Yip Y.L., Huen M.S.Y. and Tsao G.S.W., Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells, PLoS ONE. PLoS ONE, 2011. |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Researcher : Yip YL |
| List of Research Outputs |
| Cheung P.Y., Yip Y.L., Tsao G.S.W., Ching Y.P. and Cheung A., Id-1 induces cell invasiveness in immortalized epithelial cells by regulating cadherin switching and Rho GTPases, Journal of Cellular Biochemistry. 2011, 112: 157-168. |
| Hau P.M., Tsang C.M., Yip Y.L., Huen M.S.Y. and Tsao G.S.W., Id1 Interacts and Stabilizes the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) in Nasopharyngeal Epithelial Cells, PLoS ONE. PLoS ONE, 2011. |
| Yip Y.L., Tsang C.M., Deng W., Cheung P.P.Y., Jin Y., Cheung A., Lung M.L. and Tsao G.S.W., Expression of Epstein-Barr Virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells. , Journal of Medical Virology. 2010, 10: 1711-23. |
| Researcher : Yu M.S. |
| List of Research Outputs |
| Cheung Y...T..., Zhang Q., Hung H.L., Lai S...W..., Yu M...S..., So K...F... and Chang R...C...C..., Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight b-amyloid peptide, Journal of Cellular and Molecular Medicine. 2011, 15(2): 244-257. |
| Researcher : Yu MS |
| List of Research Outputs |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime MTOR suppression in low molecular weight Ab induced autophagy, Alzheimer's & Dementia. 2010, 6(4) Supplement: S243. |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime mTOR suppression in low molecular weight Abeta induced autophagy, Alzheimer's and Dementia (Suppl. 1). 2010, S243. |
| Researcher : Yu WY |
| List of Research Outputs |
| Li S.Y., Yang D., Yeung C.M., Yu W.Y., Chang R.C.C., So K.F., Wong D.S.H. and Lo A.C.Y., Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury, PLoS One. 2011, 6(1): e16380. |
| Yu W.Y., Grierson I., Sheridan C.M., Lo A.C.Y., So K.F. and Wong D.S.H., Bovine corneal endothelial precursors isolated by sphere-forming assay, UK National; Stem Cell Network Scientific Conference 2011. |
| Researcher : Zhang E |
| List of Research Outputs |
| Zhang E., Yau S.Y., Lau W.M., Lee T.M.C., Chang R.C.C. and So K.F., Promotion of neurogenesis and preservation of dendrites by wolfberry in experimental depression, The 7th International Conference on Cognitive Sciences, August 17-20, 2010, Beijing, China.. 2010, 208. |
| Researcher : Zhang Q |
| List of Research Outputs |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime MTOR suppression in low molecular weight Ab induced autophagy, Alzheimer's & Dementia. 2010, 6(4) Supplement: S243. |
| Chang R.C.C., Cheung Y.T., Zhang Q., Hung H.L., Lai S.W. and Yu M.S., Disruptions of endoplasmic reticulum and mitochondria prime mTOR suppression in low molecular weight Abeta induced autophagy, Alzheimer's and Dementia (Suppl. 1). 2010, S243. |
| Chang R.C.C., Zhang Q., Hung H.L., Wuwongse S. and Ho Y.S., Mechanisms of cell death in Alzheimer's disease, The Eighth Asia Pacific Multidisciplinary Meeting for Nervous System Diseases, Jan. 7-8, 2011 Hong Kong. 2011, 23. |
| Chang R.C.C., Zhang Q., Hung H.L. and Ho Y.S., Molecular mechanisms of initiating autophagy by oligomeric beta-amyloid peptide., The Croucher Foundation Conference, Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insightes. 2011, 19. |
| Chang R.C.C., Zhang Q., Hung H.L. and Cheung Y.T., Perturbation of endoplasmic reticulum and mitochondria rather than reduced activity of mTOR trigger autophagy in neurons exposed to low molecular weight beta-amyloid peptide, Society for Neuroscience 2010, San Diego, USA. 2010, 247.14/H60. |
| Chang R.C.C., Zhang Q., Hung H.L., Ho Y.S. and Wuwongse S., Signaling mechanism from endoplasmic reticulum collapse to induction of autophagy in neurons stressed with low molecular weight beta-amyloid peptides, The 10th International Conference on Alzheimer's & Parkinson's Disease, Barcelona, March 9-13, 2011. Abstract 350. |
| Chang R.C.C., Hung H.L., Wuwongse S., Zhang Q. and Ho Y.S., Stress responses of mitochondria to beta-amyloid peptide in Alzheimer's disease: do we understand the biological mechanisms now?, Croucher Advanced Study Institutes in Stress Responses of Mitochondria in Diabetes and Aging.. 2011. |
| Cheung Y...T..., Zhang Q., Hung H.L., Lai S...W..., Yu M...S..., So K...F... and Chang R...C...C..., Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight b-amyloid peptide, Journal of Cellular and Molecular Medicine. 2011, 15(2): 244-257. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453. |
| Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17. |
| Hung C.H.L., Cheung Y.T., Wuwongse S., Zhang Q. and Chang R.C.C., Relationship between low molecular weight beta-amyloid peptide-induced fission/fusion imbalance and mitochondrial functions, Society for Neuroscience 2010, San Diego, USA. 2010, 247.15/H61. |
| Hung H.L., Cheung Y.T., Wuwongse S., Zhang Q., Ho Y.S. and Chang R.C.C., Mitochondria in Alzheimer's Disease: Relationship between morphology and functions, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P27. |
| Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54. |
| Wong G.T.H., Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone on cytoskeleton in dendrites and dendritic spines, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 67 P49. |
| Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Amyloid beta and corticosterone-mediated synaptic dysfunction, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 66 P46. |
| Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Chang R.C.C. and Law A.C.K., Neuroprotective role of antidepressants in amyloid and corticosterone-mediated synaptic dysfunction., The Croucher Foundation Conference: Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insights.. 2011, 29. |
| Zhang Q., Hung H.L., Ho Y.S., Wuwongse S. and Chang R.C.C., Aggregation of the endoplasmic reticulum triggered by oligomeric Ab could facilitate formation of autophagosomes, Sixth International Symposium on Healthy Aging, March 5-6, 2011 Hong Kong. 2011, 47. |
| Zhang Q., Cheung Y.T., Ho Y.S. and Chang R.C.C., Low molecular weight Abeta induces autophagosome accumulation via endoplasmic reticulum aggregation, Society for Neuroscience 2010, San Diego, USA. 2010, 247.2/H48. |
| Researcher : Zhang W |
| List of Research Outputs |
| Yuan Q.J., Hu B., Chu T.H., Su H., Zhang W., So K.F., Lin Z. and Wu W., Co-expression of GAP-43 and nNOS in avulsed motoneurons and their potential role for motoneuron regeneration, Nitric Oxide. 2010, 23: 258-263. |
| Researcher : Zhang X |
| List of Research Outputs |
| Yeung P.K.K., Lai K.W., Son H.J., Zhang X., Hwang O., Chung S.S.M. and Chung S.K., Aldose reductase-deficiency leads to more significant loss of dopaminergeric neurons with incresed levels of dopamine, tetrahydrobiopterin and free radical accumulation under experimental Parkinson's Disease condition, Society for Neuroscience 2010. |
| Zhang X., Effects of endothelial specific over-expression of endothelin-1 on congnitive function. 2011, 231 pages. |
| Zhang X., Chung S.S.M. and Chung S.K., Hypertensive mice with over-expression of endothelin-1 show hyperactivity, impaired sensorimotor gating, mild congnitive deficit and cerebral vascular oxidative stress, FENS Abstracts. 2010, 5: 204.9. |
| Researcher : Zhang X |
| List of Research Outputs |
| Yeung P.K.K., Lai K.W., Son H.J., Zhang X., Hwang O., Chung S.S.M. and Chung S.K., Aldose reductase-deficiency leads to more significant loss of dopaminergeric neurons with incresed levels of dopamine, tetrahydrobiopterin and free radical accumulation under experimental Parkinson's Disease condition, Society for Neuroscience 2010. |
| Zhang X., Effects of endothelial specific over-expression of endothelin-1 on congnitive function. 2011, 231 pages. |
| Zhang X., Chung S.S.M. and Chung S.K., Hypertensive mice with over-expression of endothelin-1 show hyperactivity, impaired sensorimotor gating, mild congnitive deficit and cerebral vascular oxidative stress, FENS Abstracts. 2010, 5: 204.9. |
| Researcher : Zhou Y |
| List of Research Outputs |
| Cai Z., Wang Q., Zhou Y., Zheng L., Chiu J. and He Q.Y., Epidermal growth factor-induced epithelial-mesenchymal transiotion in human esophageal carcinoma cells --a model for the study of metastasis, Cancer Letters. 2010, 296(1): 88-95. |
| Chiu K., Yeung S.C., Lok C.K.M., Zhou Y., Chang R.C.C. and So K.F., Neuroimmune responses of polysacharides from lycium barbarum (wolfberry) in retina after experimental glaucoma, The Consortium for Globalization of Chinese Medicine, August 23-25, 2010 Hong Kong. 2010, 102 No.121. |