DEPT OF PSYCHIATRY



Researcher : Chan CY

List of Research Outputs

Koh Y.W., Lee A.M., Lee C.P., Leung K.Y., Chan C.Y., Tang C.S.K. and Chung K.F., Identifying relationship among perceived stress, stress symptoms and related risk factors among expectant fathers during transition to fatherhood using the threat appraisal model. , Health Research Symposium. 2010.
Koh Y.W., Lee A.M., Lee C.P., Chung K.F., Chan C.Y. and Tang C.S.K., Identifying relationship between perceived stress, stress symptoms and related factors amonf expectant fathers during transition to fatherhood using the threat appraisal model: Gender role and traditionalism-modernity as moderators., Research Postgraduate Symposium. 2010.


Researcher : Chan KKS

List of Research Outputs

Chan K.K.S., Hui C.L.M., Lam M.L.M., Tang Y.M., Wong G.H.Y., Chan K.W. and Chen E.Y.H., A Three-year Prospective Study of Spontaneous Eye-blink Rate in First-episode Schizophrenia: Relationship with Relapse and Neurecognitive Function, East Asian Archives of Psychiatry. 2010, 20 (4): 174-179.
Chan K.K.S., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Chan K.W., Lam M.M.L. and Chen E.Y.H., Random number generation deficit in early schizophrenia, Perceptual and Motor Skills. 2011, 112 (1): 91-103.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.


Researcher : Chan KSK

List of Research Outputs

Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.
Chan K.W., Chan K.S.K., Lam M.M.L., Chiu C.P.Y., Law C.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Correlate of insight in first episode psychosis : a longitudinal perspective, Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK) (December 11-13). 2010.


Researcher : Chan KW

Project Title:fMRI investigation of self-relevance in schizophrenia patients
Investigator(s):Chan KW, Chen EYH, Chiu CPY, Lam MLM, Hui CLM, Wong GHY
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:12/2009


Project Title:A 10-year outcome study of an early intervention program for psychosis in Hong Kong (EASY) compare with standard care service
Investigator(s):Chan KW, Chen EYH, Lam MLM, Chiu CPY
Department:Psychiatry
Source(s) of Funding:Commissioned Research on Mental Health Policy and Services
Start Date:06/2010


List of Research Outputs

Chan K.K.S., Hui C.L.M., Lam M.L.M., Tang Y.M., Wong G.H.Y., Chan K.W. and Chen E.Y.H., A Three-year Prospective Study of Spontaneous Eye-blink Rate in First-episode Schizophrenia: Relationship with Relapse and Neurecognitive Function, East Asian Archives of Psychiatry. 2010, 20 (4): 174-179.
Chan K.K.S., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Chan K.W., Lam M.M.L. and Chen E.Y.H., Random number generation deficit in early schizophrenia, Perceptual and Motor Skills. 2011, 112 (1): 91-103.
Chan K.W., Chan K.S.K., Lam M.M.L., Chiu C.P.Y., Law C.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Correlate of insight in first episode psychosis : a longitudinal perspective, Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK) (December 11-13). 2010.
Chan K.W., Pharmacological Models of Psychosis-Amphetamine and Ketamine, Medical Bulletin. 2011, 16 (5): 14-16.
Chang W.C., Hui C.L.M., Lam M.M.L., Chan K.W., Wong G.H.Y., Tang Y.M. and Chen E.Y.H., Negative symptoms and neurocognitive deficits in first-episode schizophrenia spectrum disorder. , Schizophrenia Bulletin. 2011, Vol. 37 (suppl. 1): 240.
Lin J., Lam M.M.L., Chiu C., Tse M., Khong P.L., Chan C., So K.F., Chan K.W., Chang W.C. and Chen E.Y.H., The impacts of yoga and exercise on neurocognitive function and symptoms in early psychosis, Schizophrenia Bulletin. 2011, 37: 171.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.
Tang Y.M., Wong G.H.Y., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Chan K.W., Chung D.W.S., Tso S., Chan K.P.M., Yip K.C., Hung S.F. and Chen E.Y.H., Early intervention for psychosis in Hong Kong-the EASY programme, Early Intervention in Psychiatry. 2010, 4 (3): 214-219.
Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.
Wong G.H.Y., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W. and Chen E.Y.H., Understanding delusions of reference in schizophrenia: Psychopathological, cognitive, and neuroimaging explorations, Scientific Symposium of the Hong Kong Schizophrenia Research Society. 2010.


Researcher : Chan RCK

List of Research Outputs

Li H.J., Chan R.C.K., McAlonan G.M. and Gong Q.Y., Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data, Schizophrenia Bulletin. 2010, 36 (5): 1029-1039.


Researcher : Chang WC

Project Title:Validation of negative symptom scale & investigation of reward learning deficits in first-episode schizophrenia
Investigator(s):Chang WC, Chen EYH, Lam MLM, Chan KW, Hui CLM, Wong GHY
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


List of Research Outputs

Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chang W.C., Hui C.L.M., Lam M.M.L., Chan K.W., Wong G.H.Y., Tang Y.M. and Chen E.Y.H., Negative symptoms and neurocognitive deficits in first-episode schizophrenia spectrum disorder. , Schizophrenia Bulletin. 2011, Vol. 37 (suppl. 1): 240.
Chang W.C., Rationale and the Local Development of Early Intervention for Psychosis, The Hong Kong Medical Diary. 2011, 16 (5): 4-6.
Lin J., Lam M.M.L., Chiu C., Tse M., Khong P.L., Chan C., So K.F., Chan K.W., Chang W.C. and Chen E.Y.H., The impacts of yoga and exercise on neurocognitive function and symptoms in early psychosis, Schizophrenia Bulletin. 2011, 37: 171.


Researcher : Chen EYH

Project Title:10th Biennial Winter Workshop on Schizophrenia N400 and P600 Event-Related Potential Responses to Neutral and Affect-laden Semantic Stimulus in Schizophrenic Patients 2) Predictors of Short-term Functional Outcome Following First Episode Psychosis 3) spontaneous Blink Rate in First-episode Schi Predictors of Short-term Functional Outcome Following First Episode Psychosis Spontaneous Blink Rate in First-episode Schizophrenic Patients: a Prospective Follow-up Study and Temporal Evolution of Extra-pyramidal Side-effects to Conventional Anti-psychotic Medications in First-episode Psychosis
Investigator(s):Chen EYH
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:02/2000


Project Title:Community case management for early psychosis: is two year an optimal duration? A randomized controlled study
Investigator(s):Chen EYH, Chiu CPY, Hui CLM, Lam MLM, Chan KW
Department:Psychiatry
Source(s) of Funding:Commissioned Research on Mental Health Policy and Services
Start Date:07/2010


Project Title:The Impacts of Yoga and Exercise on Neuro-cognitive Function and Symptoms in Early Psychosis - A single-blinded randomized controlled clinical trial
Investigator(s):Chen EYH, Chiu CPY, Tse MA, Khong PL, Lee TMC, Chan CLW, So KF
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:03/2011


List of Research Outputs

Chan K.K.S., Hui C.L.M., Lam M.L.M., Tang Y.M., Wong G.H.Y., Chan K.W. and Chen E.Y.H., A Three-year Prospective Study of Spontaneous Eye-blink Rate in First-episode Schizophrenia: Relationship with Relapse and Neurecognitive Function, East Asian Archives of Psychiatry. 2010, 20 (4): 174-179.
Chan K.K.S., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Chan K.W., Lam M.M.L. and Chen E.Y.H., Random number generation deficit in early schizophrenia, Perceptual and Motor Skills. 2011, 112 (1): 91-103.
Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.
Chan K.W., Chan K.S.K., Lam M.M.L., Chiu C.P.Y., Law C.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Correlate of insight in first episode psychosis : a longitudinal perspective, Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK) (December 11-13). 2010.
Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chang W.C., Hui C.L.M., Lam M.M.L., Chan K.W., Wong G.H.Y., Tang Y.M. and Chen E.Y.H., Negative symptoms and neurocognitive deficits in first-episode schizophrenia spectrum disorder. , Schizophrenia Bulletin. 2011, Vol. 37 (suppl. 1): 240.
Chen E.Y.H., Development of early psychosis work in Hong Kong: experiences, data, and reflections, New Zealand Schizophrenia Research Group Annual Meeting. 2010.
Chen E.Y.H., Early Psychosis in Hong Kong, Asian Psychiatry Forum 2011. 2011.
Chen E.Y.H., Early Psychosis: principle and practise in real life, Asian Congress on Schizophrenia Research (Feb 11-12, 2011). 2011.
Chen E.Y.H., Early psychosis work in Hong Kong: developments and outcome, World Mental Health Day 2010 (Oct 10, 2010). 2010.
Chen E.Y.H., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Yao T.J., Hung S.F. and Honer W.G., Maintenance therapy in patients with remitted first-episode psychosis following one year of treatment: a randomised controlled study comparing discontinuation versus quetiapine, British Medical Journal. 2010, 341: C4024.
Chen E.Y.H., The management of psychosis in a comprehensive service setting: experience from Hong Kong's EASY service, 6th National Congress of Schizophrenia. 2010.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Chiu C.P.Y., Lam M.M.L., Chan S.K., Chung D.W., Hung S.F., Tang Y.M., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Naming Psychosis: the Hong Kong experience, Early Intervention in Psychiatry. 2010, 4 (4): 270-274.
Garcia-Barcelo M.M., Miao X.P., Tang S.M., So H.C., Tang W.K., Leon T.Y.Y., So M.T., Yip B.H.K., Chen R.Y.L., Cheung E.F.C., Chen E.Y.H., Li T., Tam P.K.H., Cherny S.S. and Sham P.C., No NRG1 V266L in Chinese patients with schizophrenia, Psychiatric Genetics. 2011, 21 (1): 47-49.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Tso S.S.F., Hung S.F., Chan K.P.M., Chung D.W.S., Yip K.C. and Chen E.Y.H., The Effects Of First Psychiatric Admission On 3-year Outcome In Patients With First Episode Psychosis In Hong Kong , In: 6th International Conference on Early Psychosis, Early Intervention, 7th International Conference on Early Psychosis, Early Intervention. 2010.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Wong G.H.Y., Chung D.W.S., Chan K.P.M., Hung S.F., Tso S.S.F. and Chen E.Y.H., The Initial Presentation on 3-Year Outcome in Patients with First Episode Psychosis in Hong Kong May M.L. Lam1*, Jennifer Y.M. Tang1, Christy L.M. Hui1, Cindy P.Y. Chiu1, Gloria H.Y. Wong1, C.W. Law2, Dicky W.S. Chung3, Kathy P.M. Chan4, Steve Tso5, S.F. Hung4 and Eric Y.H. Chen1, World Psychiatric Association Congress, Beijing, China 2010 Sept 1-5. 2010.
Lam M.L.M., Tang Y.M., Hui C.L.M., Yew C.W.S., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S.S.F., Wong G.H.Y., Yip K.C., Hung S.F. and Chen E.Y.H., Three-year outcome of Early Intervention Programme for Psychosis (EASY) in Hong Kong, Second Joint International Conference of The HK College of Psychiatrists and The Royal College of Psychiatrists (UK), Hong Kong2010 Dec 11-13 Brain, Behavior and Mind 2010 (BBM10)Advancing Psychiatric Care in the East . 2010.
Lam M.M.L., Pearson V., Ng R.M., Chiu C.P.Y., Law C.W. and Chen E.Y.H., What does recovery from psychosis Mean? Perceptions of young first-episode patients, International Journal of Social Psychiatry. 2011, 57 (3): 248-262.
Lin J., Lam M.M.L., Chiu C., Tse M., Khong P.L., Chan C., So K.F., Chan K.W., Chang W.C. and Chen E.Y.H., The impacts of yoga and exercise on neurocognitive function and symptoms in early psychosis, Schizophrenia Bulletin. 2011, 37: 171.
Lin J.X., Lam M.M.L., Chan K.W., Chang W.C., Joe G., Chiu C.P.Y., Khong P.L., Chan C.L.W., So K.F., Tse M. and Chen E.Y.H., The impacts of yoga and exercise on cognition and symptoms in early psychosis, 13th Interventional Congress on Schizophrenia Research. . April 2-6, 2011, Colorado Springs, Colorado, USA. . 2011.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.
Liu H., Kaneko Y., Ouyang X., Li L., Hao Y., Chen E.Y.H., Jiang T., Zhou Y. and Liu Z., Schizophrenic Patients and Their Unaffacted Siblings Share Increased Resting-State Connectivity in the Task-Negative Network but Not its Anticorrelated Task-Positive Network, Schizophrenia Bulletin. 2010.
Tang Y.M., Wong G.H.Y., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Chan K.W., Chung D.W.S., Tso S., Chan K.P.M., Yip K.C., Hung S.F. and Chen E.Y.H., Early intervention for psychosis in Hong Kong-the EASY programme, Early Intervention in Psychiatry. 2010, 4 (3): 214-219.
Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.
Wong G.H.Y., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W. and Chen E.Y.H., Understanding delusions of reference in schizophrenia: Psychopathological, cognitive, and neuroimaging explorations, Scientific Symposium of the Hong Kong Schizophrenia Research Society. 2010.
Xu J., Hui C.L.M., Wong G.H.Y., Tang Y.M., Lam M.M.L., Chiu C.P.Y. and Chen E.Y.H., Current situation and service for young people suffering from early psychosis in Hong Kong. , Journal of Youth Studies. 2011, 9-18.


Researcher : Chen RYL

List of Research Outputs

Garcia-Barcelo M.M., Miao X.P., Tang S.M., So H.C., Tang W.K., Leon T.Y.Y., So M.T., Yip B.H.K., Chen R.Y.L., Cheung E.F.C., Chen E.Y.H., Li T., Tam P.K.H., Cherny S.S. and Sham P.C., No NRG1 V266L in Chinese patients with schizophrenia, Psychiatric Genetics. 2011, 21 (1): 47-49.


Researcher : Cherny SS

Project Title:Variance components models for mapping QTLs
Investigator(s):Cherny SS, Sham PC
Department:Psychiatry
Source(s) of Funding:National Institutes of Health, US Department of Health and Human Services - General Award
Start Date:09/2006


Project Title:Genome-wide association mapping of susceptibility loci for symptomatic epilepsy
Investigator(s):Cherny SS, Sham PC
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2009
Completion Date:12/2010


Project Title:Genotype by risk factor interactions in cognitive decline: The Guangzhou Biobank Cohort Study
Investigator(s):Cherny SS, Jiang CQ, Lam TH, Law ACK, Sham PC
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


Project Title:Exon sequencing of Semaphorin, a novel Hirschsprung's Disease susceptibility locus
Investigator(s):Cherny SS, Tam PKH, Garcia-Barcelo MM, Sham PC
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010


Project Title:60th Annual Meeting of the American Society of Human Genetics A Genome-Wide Association Study of Symptomatic Epilepsy in Han Hong Kong Chinese Detects Multiple Variants
Investigator(s):Cherny SS
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:11/2010
Completion Date:11/2010


Project Title:Meta-analysis of Chinese and European genome-wide association studies of Hirshsprung's disease and confirmation of novel loci
Investigator(s):Cherny SS, Garcia-Barcelo MM, Sham PC, Tam PKH
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2011


List of Research Outputs

Cherny S.S., Guo Y., Sham P.C., Baum L. and Kwan P., A genome-wide association study of symptomatic epilepsy in Han Chinese detects multiple variants, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2638/F, Washington, D.C., USA, November 5, 2010. 764.
Cherny S.S., Associate Editor (from 1997 to present), Behavior Genetics. 2011.
Cherny S.S., Editorial Board, Genetics Research International. 2011.
Cherny S.S., Member, Editorial Advisory Board, Open Genetics Reviews. Bentham Science, 2010.
Cherny S.S., Member, Editorial Advisory Board, The Open Genomics Journal. Bentham Science, 2010.
Cherny S.S., PLoS One. 2010.
Cherny S.S., Small sample GWAS: some successes, Center for Education and Drug Abuse Research, University of Pittsburgh. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Association of a genetic variant in adrenomedullin gene with its plasma level , Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Gamma-glutamyl transaminase level predicts the development of hypertension., Poster Presentation at the 23rd Scientific Meeting of the International Society of Hypertension, Vancouver. 2010.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Gamma-glutamyl transferase level predicts the development of hypertension in Hong Kong Chinese, Clin Chim Acta. 2011, 412(15-16): 1326-1331.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Gamma-glutamyl transferase level predicts the development of hypertension in Hong Kong Chinese, Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Thomas G.N., Lam T.H. and Lam K.S.L., Mendelian randomisation analysis suggests that plasma interleukin-6 is raised in hypertension but does not cause its development, Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Plasma adrenomedullin level is related to plasma interleukin-6 and a polymorphism in the adrenomedullin gene, Basic & Clinical Pharmacology & Toxicology. Presented at the 10th Congress of the European Association for Clinical Pharmacology and Therapeutics, Budapest. 2011, 109 (Suppl. 1): 102-103.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Role of genetic variants in gene encoding lipocalin-2 in the development of elevated blood pressure, Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Lam K.S.L., Cherny S.S. and Sham P.C., Using glycosylated haemoglobin to define the metabolic syndrome in United States adults, Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Lam K.S.L., Cherny S.S. and Sham P.C., Using glycosylated hemoglobin to define the metabolic syndrome in United States adults. , Oral Presentation at the 23rd Scientific Meeting of the International Society of Hypertension, Vancouver. 2010.
Garcia-Barcelo M.M., Tang C., Tang W.K., So M.T., Sham P.C., Cherny S.S. and Tam P.H., Fine mapping of the NRG1 Hirschsprungs-associated gene, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 1155/F, Washington, D.C., USA, November 5, 2010. 361.
Garcia-Barcelo M.M., Miao X.P., Tang S.M., So H.C., Tang W.K., Leon T.Y.Y., So M.T., Yip B.H.K., Chen R.Y.L., Cheung E.F.C., Chen E.Y.H., Li T., Tam P.K.H., Cherny S.S. and Sham P.C., No NRG1 V266L in Chinese patients with schizophrenia, Psychiatric Genetics. 2011, 21 (1): 47-49.
Ho J.W.C., Choi S.C., Lee Y.F., Hui T.C.K., Cherny S.S., Garcia-Barcelo M.M., Carvajal-Carmona L., Liu R., To S.H., Yau T.K., Chung C.C., Yau C.C., Hui S.M., Lau P.Y., Yuen C.H., Wong Y.W., Ho S., Fung S.S., Thomlinson I.P., Houlston R.S., Cheng K.K. and Sham P.C., Replication study of SNP associations for colorectal cancer in Hong Kong Chinese, British Journal of Cancer. 2010, 104(2): 369-375.
Kwan S.H., Cherny S.S. and Sham P.C., Assessing statistical significance in PLINK segmental sharing test, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2844/W, Washington, D.C., USA, November 3, 2010. 818.
Li M., Sham P.C., Cherny S.S. and Song Y., A knowledge-based weighting framework to boost the power of genome-wide association studies, PLoS One. 2010, 5 (12): e14480.
Li M., Sham P.C. and Cherny S.S., A powerful approach to efficiently combine p-values for gene-based association analysis, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2815/W, Washington, D.C., USA, November 3, 2010. 811.
Ong K.L., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Lam T.H., Cheung B.M.Y. and Lam K.S.L., A genetic variant in the gene encoding adrenomedullin predicts the development of dysglycemia over 6.4 years in Chinese, Clin Chim Acta. 2010, 412: 353-7.
Ong K.L., Cheung B.M.Y., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Association of a genetic variant in adrenomedullin gene with its plasma level., Oral Presentation at the Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction, Hong Kong. 2010.
Ong K.L., Li M., Tso A.W.K., Xu A., Cherny S.S., Sham P.C., Tse H.F., Lam T.H., Cheung B.M.Y. and Lam K.S.L., Association of genetic variants in the adiponectin gene with adiponectin level and hypertension in Hong Kong Chinese. , European Journal of Endocrinology. 2010, 163: 251-257.
Ong K.L., Tso A.W.K., Lam K.S.L., Cherny S.S., Sham P.C. and Cheung B.M.Y., Using glycosylated hemoglobin to define the metabolic syndrome in United States adults, Diabetes Care. 2010, 23: 1856-8.
Sham P.C. and Cherny S.S., Genetic architecture of complex diseases. In E Zeggini and A Morris (eds), Analysis of Complex Disease Association Studies: A Practical Guide. Elsevier, Oxford, 2010, 1-13.
So H.C., Gui H., Cherny S.S. and Sham P.C., Evaluating the Heritability Explained by Known Susceptibility Variants: A Survey of Ten Complex Diseases, Genetic Epidemiology. 2011, 35 (5): 310-317.
So H.C., Kwan S.H., Cherny S.S. and Sham P.C., Risk Prediction Of Complex Diseases From Family History And Known Susceptibility Loci, With Applications For Cancer Screening, the American Journal Of Human Genetics . 2011, 88: 548-565.
Tang S.M., Tang W.K., So M.T., Miao X., Leung M.C., Yip B.H.K., Leon Y.Y., Ngan E.S.W., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wu X.Z., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Fine mapping of the NRG1 Hirschsprung's disease locus, PLoS One. 2011, 6(1): e16181.
Toulopoulou T., Goldberg T.E., Rebollo Mesa I., Picchioni M., Rijsdijk F., Stahl D., Cherny S.S., Sham P.C., Faraone S.V., Tsuang M., Weinberger D.R., Seidman L.J. and Murray R.M., Impaired Intellect and Memory: A Missing Link Between Genetic Risk and Schizophrenia?, Archives of General Psychiatry. 2010, 67 (9): 905-913.
Waye M.M.Y., Baum L., Boyde T.R.C., Chan K.K.K., Cherny S.S., Choy F., Garcia-Barcelo M.M., Gong Z., Kagawa H., Kotaka M., Lee C.Y., Lee S.M.Y., Li H.Y., Meng H., Ng R.K., Ng T.B., Pollard J., Qi R., Shen D.W., Tam S.S.W., Tsang F.S.Y., Wasylyk B., Xue H. and Siu C.O., Journal of Biochemistry and Molecular Biology in the Post Genomic Era. 2010.
Wong E.H.M., Tang S.M., Garcia-Barcelo M.M., Zhang X.J., Liu J.J., Cherny S.S., Sham P.C. and Tam P.K.H., Genomi-wide association study on anorectal malformations in the Chinese population, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2942/T, Washington, D.C., USA, November 5, 2010. 846.
Xiao S., Cherny S.S., Li H.Y., Gao Y., Tso H.W., Lau K.S., Luk K.D.K., Sham P.C. and Kung A.W.C., Association Of Jag1 Gene And Its Variant Sequence With Bone Mineral Density And Osteoporotic Fractures: A Genome-wide Association Study And Follow-up Replication Studies, The HKSEMR Annual Scientific Meeting and Annual General Meeting, 21 November, Hong Kong. 2010.
Yang H.C., Liang L.J., Chiang K.M., Thomas G., Tomlinson B., Cherny S.S., Guo Y., Lam T.H., Chen J.W. and Pan W.H., A genome-wide gene-based associated study identifies SLC4A4, WWOX and COMMD7 as hypertension susceptibility genes in a Han Chinese population, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 736/W, Washington D.C., USA, November 3, 2010. 240.
Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607.
Zhang L., Yang W., Ying D., Cherny S.S., Hildebrandt F., Sham P.C. and Lau Y.L., Homozygosity Mapping on a Single Patient-Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data, Human Mutation. 2011, 32 (3): 345-353.
Zhang X.W., Cherny S.S., Huang Y., Gao X., Xiang Y., Fu Y.X., Meng H.Q., Ma X.H., Wang Y.C., Li T. and Sham P.C., Effect of parental age on children's intelligence in the Southwestern China Prospective twin registry, Behavior Genetics. 2010, 40 (6): 820.
Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234.


Researcher : Cheung C

Project Title:A single cohort prospective MRI study of symptoms and brain structure maturation in autism
Investigator(s):Cheung C, McAlonan GM, Chua SE, Sham PC
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:12/2008


List of Research Outputs

Cheung C., "What do Schizophrenia and Bipolar Disorder have in common: A MRI prospective”, The Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK), Hong Kong. 2010.
Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.
Cheung C., Yu G.K.K., Yam A., Myint V., Chua S.E. and McAlonan G.M., Intra-orbital distance as a record of social brain dysmorphology in autism, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Cheung C., McAlonan G.M., Fung Y.Y., Fung C.M.G., Yu K.K.K., Tai K.S., Sham P.C. and Chua S.E., MRI Study of Minor Physical Anomaly in Childhood Autism Implicates Aberrant Neurodevelopment in Infancy, PLoS One. 2011, 6 (6): e20246.
Cheung C., Volunteers in mental health NGOs: Comparison between Taiwan and Hong Kong, The Mental Health Association of Hong Kong, Hong Kong. 2011.
Cheung C., Li Q., Wu E.X. and McAlonan G.M., Voxel-based morphometry using DARTEL in the mouse reveals differential impact of early and late prenatal inflammation on adult brain, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Leung M.K., Cheung C., Yu K.K.K., Yip B.H.K., Sham P.C., Li Q., Chua S.E. and McAlonan G.M., Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting, Schizophrenia Bulletin. 2011, 37 (1): 199-211.
McAlonan G.M., Li Q., Wu E.X. and Cheung C., A DARTEL based analysis of post-natal brain response to prenatal maternal inflammation in early or late pregnancy in the mouse, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
McAlonan G.M., Li Q. and Cheung C., The Timing and Specificity of Prenatal Immune Risk Factors for Autism Modeled in the Mouse and Relevance to Schizophrenia, Neurosignals. 2011, 18 (2): 129-139.
Wang Q., Deng W., Huang C., Li M., Ma X., Wang Y., Jiang L., Lui S., Huang X., Chua S.E., Cheung C., McAlonan G.M., Sham P.C., Murray R.M., Collier D.A., Gong Q. and Li T., Abnormalities in connectivity of white-matter tracts in patients with familial and non-familial schizophrenia., Psychological Medicine. 2010, 41 (8): 1691-1700.
Wong C., Yu G.K.K., Chua S.E., Cheung C. and McAlonan G.M., Do Autism Spectrum Disorders and Bipolar Disorder share a neuroanatomical phenotype?, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
Yu G.K.K., Pun E., Wong P., Chua S.E., Cheung C. and McAlonan G.M., Do Autism Spectrum Disorders and Obsessive Compulsive Disorders share a neuroanatomical phenotype?, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
Yu G.K.K., Cheung C., Fung Y.Y., Fung G., McAlonan G.M. and Chua S.E., MRI brain scan study of minor physical anomalies in autism, Autism 2010 - Geneva Centre for Autism's International Symposium (November 3-5, 2010). 2010.
Yu K.K.K., Cheung C., Leung M.K., Li Q., Chua S.E. and McAlonan G.M., Are bipolar disorder and schizophrenia neuroanatomically distinct? An anatomical likelihood meta-analysis, Frontiers in Human Neuroscience. 2010, 26 (4): 189.
Yu K.K.K., Cheung C., Chua S.E. and McAlonan G.M., Can Asperger syndrome be distinguished from autism? An anatomic likelihood meta-analysis of MRI studies, Journal of Psychiatry and Neuroscience. 2011, 36 (2).


Researcher : Cheung EFC

List of Research Outputs

Garcia-Barcelo M.M., Miao X.P., Tang S.M., So H.C., Tang W.K., Leon T.Y.Y., So M.T., Yip B.H.K., Chen R.Y.L., Cheung E.F.C., Chen E.Y.H., Li T., Tam P.K.H., Cherny S.S. and Sham P.C., No NRG1 V266L in Chinese patients with schizophrenia, Psychiatric Genetics. 2011, 21 (1): 47-49.


Researcher : Cheung V

List of Research Outputs

Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.


Researcher : Chiu CPY

Project Title:Paternal age effect on the outcome of first episode psychosis
Investigator(s):Chiu CPY, Chen EYH, Lam MLM, Chan KW, Hui CLM
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2009


List of Research Outputs

Chan K.K.S., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Chan K.W., Lam M.M.L. and Chen E.Y.H., Random number generation deficit in early schizophrenia, Perceptual and Motor Skills. 2011, 112 (1): 91-103.
Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.
Chan K.W., Chan K.S.K., Lam M.M.L., Chiu C.P.Y., Law C.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Correlate of insight in first episode psychosis : a longitudinal perspective, Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK) (December 11-13). 2010.
Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chen E.Y.H., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Yao T.J., Hung S.F. and Honer W.G., Maintenance therapy in patients with remitted first-episode psychosis following one year of treatment: a randomised controlled study comparing discontinuation versus quetiapine, British Medical Journal. 2010, 341: C4024.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Chiu C.P.Y., Lam M.M.L., Chan S.K., Chung D.W., Hung S.F., Tang Y.M., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Naming Psychosis: the Hong Kong experience, Early Intervention in Psychiatry. 2010, 4 (4): 270-274.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Tso S.S.F., Hung S.F., Chan K.P.M., Chung D.W.S., Yip K.C. and Chen E.Y.H., The Effects Of First Psychiatric Admission On 3-year Outcome In Patients With First Episode Psychosis In Hong Kong , In: 6th International Conference on Early Psychosis, Early Intervention, 7th International Conference on Early Psychosis, Early Intervention. 2010.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Wong G.H.Y., Chung D.W.S., Chan K.P.M., Hung S.F., Tso S.S.F. and Chen E.Y.H., The Initial Presentation on 3-Year Outcome in Patients with First Episode Psychosis in Hong Kong May M.L. Lam1*, Jennifer Y.M. Tang1, Christy L.M. Hui1, Cindy P.Y. Chiu1, Gloria H.Y. Wong1, C.W. Law2, Dicky W.S. Chung3, Kathy P.M. Chan4, Steve Tso5, S.F. Hung4 and Eric Y.H. Chen1, World Psychiatric Association Congress, Beijing, China 2010 Sept 1-5. 2010.
Lam M.M.L., Pearson V., Ng R.M., Chiu C.P.Y., Law C.W. and Chen E.Y.H., What does recovery from psychosis Mean? Perceptions of young first-episode patients, International Journal of Social Psychiatry. 2011, 57 (3): 248-262.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.
Tang Y.M., Wong G.H.Y., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Chan K.W., Chung D.W.S., Tso S., Chan K.P.M., Yip K.C., Hung S.F. and Chen E.Y.H., Early intervention for psychosis in Hong Kong-the EASY programme, Early Intervention in Psychiatry. 2010, 4 (3): 214-219.
Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.
Wong G.H.Y., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W. and Chen E.Y.H., Understanding delusions of reference in schizophrenia: Psychopathological, cognitive, and neuroimaging explorations, Scientific Symposium of the Hong Kong Schizophrenia Research Society. 2010.


Researcher : Choi SC

List of Research Outputs

Ho J.W.C., Choi S.C., Lee Y.F., Hui T.C.K., Cherny S.S., Garcia-Barcelo M.M., Carvajal-Carmona L., Liu R., To S.H., Yau T.K., Chung C.C., Yau C.C., Hui S.M., Lau P.Y., Yuen C.H., Wong Y.W., Ho S., Fung S.S., Thomlinson I.P., Houlston R.S., Cheng K.K. and Sham P.C., Replication study of SNP associations for colorectal cancer in Hong Kong Chinese, British Journal of Cancer. 2010, 104(2): 369-375.


Researcher : Chua SE

Project Title:A study of the psychological effects of the H1N1 pandemic in Hong
Investigator(s):Chua SE, Lee AM, McAlonan GM
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2010
Completion Date:06/2011


Project Title:MRI brain scan to predict 1 year outcome in newly-diagnosed schizophrenia.
Investigator(s):Chua SE, McAlonan GM, Tai KS
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


Project Title:King's/HKU Fellowship Awards 2010-11
Investigator(s):Chua SE
Department:Psychiatry
Source(s) of Funding:King's/HKU Fellowship Awards
Start Date:09/2010


Project Title:Predicting and preventing schizophrenia in the mouse model.
Investigator(s):Chua SE, Wu EX, McAlonan GM
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2010


List of Research Outputs

Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.
Cheung C., Yu G.K.K., Yam A., Myint V., Chua S.E. and McAlonan G.M., Intra-orbital distance as a record of social brain dysmorphology in autism, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Cheung C., McAlonan G.M., Fung Y.Y., Fung C.M.G., Yu K.K.K., Tai K.S., Sham P.C. and Chua S.E., MRI Study of Minor Physical Anomaly in Childhood Autism Implicates Aberrant Neurodevelopment in Infancy, PLoS One. 2011, 6 (6): e20246.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Chua S.E., Fellowship 2010-2011, HKU / King's College London, UK. 2010.
Chua S.E., Invited Speaker for lecture entitled "Minor physical anomalies on MRI : Relevance to childhood autism and aberrant neurodevelopment in infancy, 7th International Conference on Cognitive Science (ICCS). Section 2, Symposium 3, p124, August 17-20, 2010, Beijing, China. 2010.
Chua S.E. and McAlonan G.M., Is there core diffusion tensor imaging pathology in schizophrenia?, British Journal of Psychiatry. 2010, 195: 83-87.
Chung A.K.K. and Chua S.E., Effects on prolongation of Bazett's corrected QT interval of seven second-generation antipsychotics in the treatment of schizophrenia: a meta-analysis, Journal of Psychopharmacology. 2011, 25 (5): 646-666.
Deng Y., Lam S.S.Y., Meyer U., Feldon J., Li Q., Wei R., Luk L.H.F., Chua S.E., Sham P.C., Wang Y. and McAlonan G.M., Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation, PLoS One . 2011, 6 (2): e16638.
Leung M.K., Cheung C., Yu K.K.K., Yip B.H.K., Sham P.C., Li Q., Chua S.E. and McAlonan G.M., Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting, Schizophrenia Bulletin. 2011, 37 (1): 199-211.
Siu M.W., Cheung T.Y., Chiu M.M., Kwok T.Y., Choi W.L., Lo T.K., Ting W.M., Yu P.H., Cheung C.Y., Wong J.G.W.S. and Chua S.E., The Preparedness of Hong Kong Medical Students towards Advance Directives and End-of-life Issues, East Asia Archives of Psychiatry. 2010, 20 (4): 155-162.
Wang Q., Deng W., Huang C., Li M., Ma X., Wang Y., Jiang L., Lui S., Huang X., Chua S.E., Cheung C., McAlonan G.M., Sham P.C., Murray R.M., Collier D.A., Gong Q. and Li T., Abnormalities in connectivity of white-matter tracts in patients with familial and non-familial schizophrenia., Psychological Medicine. 2010, 41 (8): 1691-1700.
Wong C., Yu G.K.K., Chua S.E., Cheung C. and McAlonan G.M., Do Autism Spectrum Disorders and Bipolar Disorder share a neuroanatomical phenotype?, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
Yu G.K.K., Pun E., Wong P., Chua S.E., Cheung C. and McAlonan G.M., Do Autism Spectrum Disorders and Obsessive Compulsive Disorders share a neuroanatomical phenotype?, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
Yu G.K.K., Cheung C., Fung Y.Y., Fung G., McAlonan G.M. and Chua S.E., MRI brain scan study of minor physical anomalies in autism, Autism 2010 - Geneva Centre for Autism's International Symposium (November 3-5, 2010). 2010.
Yu K.K.K., Cheung C., Leung M.K., Li Q., Chua S.E. and McAlonan G.M., Are bipolar disorder and schizophrenia neuroanatomically distinct? An anatomical likelihood meta-analysis, Frontiers in Human Neuroscience. 2010, 26 (4): 189.
Yu K.K.K., Cheung C., Chua S.E. and McAlonan G.M., Can Asperger syndrome be distinguished from autism? An anatomic likelihood meta-analysis of MRI studies, Journal of Psychiatry and Neuroscience. 2011, 36 (2).


Researcher : Chung AKK

List of Research Outputs

Chung A.K.K. and Chua S.E., Effects on prolongation of Bazett's corrected QT interval of seven second-generation antipsychotics in the treatment of schizophrenia: a meta-analysis, Journal of Psychopharmacology. 2011, 25 (5): 646-666.


Researcher : Chung KF

Project Title:Seizure threshold of unilateral electroconvulsive therapy
Investigator(s):Chung KF, Wong SJ
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:07/2001


Project Title:Influence of a psychiatric clerkship on medical students' attitudes toward psychiatry and mental patients
Investigator(s):Chung KF
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:01/2002


Project Title:Response to moderately suprathreshold unilateral (UL) electroconvulsive therapy (ECT): an examination of possible predictors
Investigator(s):Chung KF, Irwin MG
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:06/2002


Project Title:A randomized controlled trial of electroacupuncture for persistent insomnia symptoms associated with major depressive disorder
Investigator(s):Chung KF, Zhang Z, Tso KC
Department:Psychiatry
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:01/2011


List of Research Outputs

Chung K.F., Acupuncture for insomnia, Hong Kong International Acupuncture Conference, Hospital Authority, January 2011 (January 14-16, 2011). 2011.
Chung K.F., Kan K.K.K. and Yeung W.F., Assessing insomnia in adolescents: comparison of Insomnia Severity Index, Athens Insomnia Scale and Sleep Quality Index, Sleep Medicine. 2011, 12 (5): 463-470.
Chung K.F. and Tso K.C., Assessing pain in depression: What do ratings on unidimensional pain scales really mean?, Comprehensive Psychiatry. 2011, 52 (2): 208-217.
Chung K.F., Tso K.C., Yeung W.F. and Li W.H., Quality of life in major depressive disorder: the role of pain and pain catastrophizing cognition., Comprehensive Psychiatry. 2011, [Epub ahead of print].
Chung K.F. and Tso K.C., Relationship between insomnia and pain in major depressive disorder: a sleep diary and actigraphy study, Sleep Medicine. 2010, 11: 752-758.
Chung K.F., Screening for bipolar disorder: what are the pitfalls?, The Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists, December 2010 (December 11-13, 2010). 2010.
Chung K.F., Understanding and treating pain-the body, the brain and the psychology, 1st AMM-AMS-HKAM Tripartite Congress/44th Malaysia-Singapore Congress of Medicine, Novermber, 2010 (November 12-14, 2010). 2010.
Chung K.F., [安眠藥] - 我真的需要嗎?, 健康與醫療/醫學教室, Apple Daily, 2010. 2010.
Chung K.F., 脾氣差程度界定情緒病, 健康與醫療/醫學教室, Apple Daily. 2010.
Dueññas H., Lee A., Brnabic A., Chung K.F., Lai C.H., Badr M.G., Uy-Ponio T., Ruiz J.R., Varrey P., Jian H. and Dossenbach M., Frequency of treatment-emergent sexual dysfunction and treatment effectiveness during SSRI or duloxetine therapy: 8-week data from a 6-month observational study, International Journal of Psychiatry in Clinical Practice. 2011, 15 (2): 80-90.
Koh Y.W., Lee A.M., Lee C.P., Leung K.Y., Chan C.Y., Tang C.S.K. and Chung K.F., Identifying relationship among perceived stress, stress symptoms and related risk factors among expectant fathers during transition to fatherhood using the threat appraisal model. , Health Research Symposium. 2010.
Koh Y.W., Lee A.M., Lee C.P., Chung K.F., Chan C.Y. and Tang C.S.K., Identifying relationship between perceived stress, stress symptoms and related factors amonf expectant fathers during transition to fatherhood using the threat appraisal model: Gender role and traditionalism-modernity as moderators., Research Postgraduate Symposium. 2010.
Liu H., Li H., Xu M., Chung K.F. and Zhang S.P., A systematic review on acupuncture for trigeminal neuralgia, Alternative Therapies in Health and Medicine. 2010, 16 (6): 30-35.
Poon M.K., Chung K.F. and Yeung W.F., Classification of Insomnia Using Traditional Chinese Medicine (TCM) Diagnostic System: A Systematic Review, Hong Kong International Acupuncture Conference: Neurological and Mental Illness. 2011.
Yeung W.F., Chung K.F. and Poon M.K., Acupuncture and Chinese Herbal Medicine for Insomnia: A Systematic Review of Effectiveness and TCM Pattern Differentiation, Hong Kong International Acupuncture Conference: Neurological and Mental Illness. 2011.
Yeung W.F., Chung K.F., Tso K.C., Zhang S.P., Zhang Z. and Ho L.M., Electroacupuncture for residual insomnia associated with major depressive disorder: A randomized controlled trial, Sleep. 2011, 34 (6): 807-815.


Researcher : Deng W

List of Research Outputs

Wang Q., Deng W., Huang C., Li M., Ma X., Wang Y., Jiang L., Lui S., Huang X., Chua S.E., Cheung C., McAlonan G.M., Sham P.C., Murray R.M., Collier D.A., Gong Q. and Li T., Abnormalities in connectivity of white-matter tracts in patients with familial and non-familial schizophrenia., Psychological Medicine. 2010, 41 (8): 1691-1700.


Researcher : Deng Y

List of Research Outputs

Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Deng Y., Lam S.S.Y., Meyer U., Feldon J., Li Q., Wei R., Luk L.H.F., Chua S.E., Sham P.C., Wang Y. and McAlonan G.M., Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation, PLoS One . 2011, 6 (2): e16638.


Researcher : Fung CMG

List of Research Outputs

Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.
Cheung C., McAlonan G.M., Fung Y.Y., Fung C.M.G., Yu K.K.K., Tai K.S., Sham P.C. and Chua S.E., MRI Study of Minor Physical Anomaly in Childhood Autism Implicates Aberrant Neurodevelopment in Infancy, PLoS One. 2011, 6 (6): e20246.


Researcher : Gui H

List of Research Outputs

Li M., Gui H., Kwan S.H. and Sham P.C., GATES: a rapid and powerful gene-based association test using extended Simes procedure., Am J Hum Genet. 2011, 88.
So H.C., Gui H., Cherny S.S. and Sham P.C., Evaluating the Heritability Explained by Known Susceptibility Variants: A Survey of Ten Complex Diseases, Genetic Epidemiology. 2011, 35 (5): 310-317.


Researcher : Guo Y

List of Research Outputs

Cherny S.S., Guo Y., Sham P.C., Baum L. and Kwan P., A genome-wide association study of symptomatic epilepsy in Han Chinese detects multiple variants, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2638/F, Washington, D.C., USA, November 5, 2010. 764.
Yang H.C., Liang L.J., Chiang K.M., Thomas G., Tomlinson B., Cherny S.S., Guo Y., Lam T.H., Chen J.W. and Pan W.H., A genome-wide gene-based associated study identifies SLC4A4, WWOX and COMMD7 as hypertension susceptibility genes in a Han Chinese population, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 736/W, Washington D.C., USA, November 3, 2010. 240.


Researcher : Hui CLM

List of Research Outputs

Chan K.K.S., Hui C.L.M., Lam M.L.M., Tang Y.M., Wong G.H.Y., Chan K.W. and Chen E.Y.H., A Three-year Prospective Study of Spontaneous Eye-blink Rate in First-episode Schizophrenia: Relationship with Relapse and Neurecognitive Function, East Asian Archives of Psychiatry. 2010, 20 (4): 174-179.
Chan K.K.S., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Chan K.W., Lam M.M.L. and Chen E.Y.H., Random number generation deficit in early schizophrenia, Perceptual and Motor Skills. 2011, 112 (1): 91-103.
Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.
Chan K.W., Chan K.S.K., Lam M.M.L., Chiu C.P.Y., Law C.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Correlate of insight in first episode psychosis : a longitudinal perspective, Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK) (December 11-13). 2010.
Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chang W.C., Hui C.L.M., Lam M.M.L., Chan K.W., Wong G.H.Y., Tang Y.M. and Chen E.Y.H., Negative symptoms and neurocognitive deficits in first-episode schizophrenia spectrum disorder. , Schizophrenia Bulletin. 2011, Vol. 37 (suppl. 1): 240.
Chen E.Y.H., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Yao T.J., Hung S.F. and Honer W.G., Maintenance therapy in patients with remitted first-episode psychosis following one year of treatment: a randomised controlled study comparing discontinuation versus quetiapine, British Medical Journal. 2010, 341: C4024.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Chiu C.P.Y., Lam M.M.L., Chan S.K., Chung D.W., Hung S.F., Tang Y.M., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Naming Psychosis: the Hong Kong experience, Early Intervention in Psychiatry. 2010, 4 (4): 270-274.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Tso S.S.F., Hung S.F., Chan K.P.M., Chung D.W.S., Yip K.C. and Chen E.Y.H., The Effects Of First Psychiatric Admission On 3-year Outcome In Patients With First Episode Psychosis In Hong Kong , In: 6th International Conference on Early Psychosis, Early Intervention, 7th International Conference on Early Psychosis, Early Intervention. 2010.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Wong G.H.Y., Chung D.W.S., Chan K.P.M., Hung S.F., Tso S.S.F. and Chen E.Y.H., The Initial Presentation on 3-Year Outcome in Patients with First Episode Psychosis in Hong Kong May M.L. Lam1*, Jennifer Y.M. Tang1, Christy L.M. Hui1, Cindy P.Y. Chiu1, Gloria H.Y. Wong1, C.W. Law2, Dicky W.S. Chung3, Kathy P.M. Chan4, Steve Tso5, S.F. Hung4 and Eric Y.H. Chen1, World Psychiatric Association Congress, Beijing, China 2010 Sept 1-5. 2010.
Lam M.L.M., Tang Y.M., Hui C.L.M., Yew C.W.S., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S.S.F., Wong G.H.Y., Yip K.C., Hung S.F. and Chen E.Y.H., Three-year outcome of Early Intervention Programme for Psychosis (EASY) in Hong Kong, Second Joint International Conference of The HK College of Psychiatrists and The Royal College of Psychiatrists (UK), Hong Kong2010 Dec 11-13 Brain, Behavior and Mind 2010 (BBM10)Advancing Psychiatric Care in the East . 2010.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.
Tang Y.M., Wong G.H.Y., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Chan K.W., Chung D.W.S., Tso S., Chan K.P.M., Yip K.C., Hung S.F. and Chen E.Y.H., Early intervention for psychosis in Hong Kong-the EASY programme, Early Intervention in Psychiatry. 2010, 4 (3): 214-219.
Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.
Wong G.H.Y., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W. and Chen E.Y.H., Understanding delusions of reference in schizophrenia: Psychopathological, cognitive, and neuroimaging explorations, Scientific Symposium of the Hong Kong Schizophrenia Research Society. 2010.
Xu J., Hui C.L.M., Wong G.H.Y., Tang Y.M., Lam M.M.L., Chiu C.P.Y. and Chen E.Y.H., Current situation and service for young people suffering from early psychosis in Hong Kong. , Journal of Youth Studies. 2011, 9-18.


Researcher : Hui TCK

List of Research Outputs

Ho J.W.C., Choi S.C., Lee Y.F., Hui T.C.K., Cherny S.S., Garcia-Barcelo M.M., Carvajal-Carmona L., Liu R., To S.H., Yau T.K., Chung C.C., Yau C.C., Hui S.M., Lau P.Y., Yuen C.H., Wong Y.W., Ho S., Fung S.S., Thomlinson I.P., Houlston R.S., Cheng K.K. and Sham P.C., Replication study of SNP associations for colorectal cancer in Hong Kong Chinese, British Journal of Cancer. 2010, 104(2): 369-375.


Researcher : Khong PL

Project Title:To establish the use of magnetic resonance imaging for assessing the degree of brain damage following hypoxic ischemic insult with or without neuroprotective therapies
Investigator(s):Khong PL, Cheung PT
Department:Diagnostic Radiology
Source(s) of Funding:Other Funding Scheme
Start Date:06/2002


Project Title:PET/CT scanning for lymphoma patients
Investigator(s):Khong PL, Liang RHS
Department:Diagnostic Radiology
Source(s) of Funding:Hong Kong Blood Cancer Foundation - General Award
Start Date:05/2007


Project Title:Imaging iron stores in the brain using susceptibility-weighted MR imaging (SWI) in patients with B-thalassaemia major (TM) and correlation with cognitive function
Investigator(s):Khong PL, Chan GCF, Fung ASM, Ha SY
Department:Diagnostic Radiology
Source(s) of Funding:Children's Thalassaemia Foundation - General Awards
Start Date:07/2007


Project Title:The University of Hong Kong PET/CT scan: a state-of-the-art imaging facility available to all
Investigator(s):Khong PL, Leong Fung LLY, Pang CBY
Department:Diagnostic Radiology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:03/2008


Project Title:ISMRM 16th Scientific Meeting & Exhibition Diffuse tensor imaging: clinical applications to children
Investigator(s):Khong PL
Department:Diagnostic Radiology
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:05/2008


Project Title:18F-FDG PET-CT in prognostication and response assessment of aggressive mature T-cell and NK-cell lymphomas
Investigator(s):Khong PL, Au WY, Kwong YL, Liang RHS, Yao T, Yeung DWC
Department:Diagnostic Radiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:08/2008


Project Title:Radiation Dose and Cancer Risk from CT and PET-CT Scan
Investigator(s):Khong PL, Mak HKF, Zhang J
Department:Diagnostic Radiology
Source(s) of Funding:Small Project Funding
Start Date:09/2008
Completion Date:08/2010


Project Title:Medical cyclotron for the production of radiopharmaceuticals for positron emission tomography imaging in an academic medical center
Investigator(s):Khong PL, Yeung DWC, Liang RHS, Kwong YL, Fan ST, Chu LW, Wu EX
Department:Diagnostic Radiology
Source(s) of Funding:UGC One-off Special Equipment Grant Scheme
Start Date:12/2008


Project Title:Web-based PET-CT imaging educational case-files
Investigator(s):Khong PL, Zhang J, Anthony M, Mak HKF, Ching ASC, Chan T
Department:Diagnostic Radiology
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:05/2009


Project Title:Upgrade of the HKU MRI scanner and imaging coils
Investigator(s):Khong PL, Luk KDK, Poon RTP, Tse HF, Kwong YL, Cheung RTF, Sham PC, Chan GCF, Wu EX, Tan L
Department:Diagnostic Radiology
Source(s) of Funding:University Development Fund - General Award
Start Date:06/2009


Project Title:PET/CT scan - a state-of-the-art imaging facility available to all
Investigator(s):Khong PL
Department:Diagnostic Radiology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:11/2009


Project Title:Dynamic FDG-PET-CT imaging for the evaluation of nasopharyngeal carcinoma (NPC): a pilot study
Investigator(s):Khong PL, Kwong DLW, Huang B
Department:Diagnostic Radiology
Source(s) of Funding:Small Project Funding
Start Date:12/2009
Completion Date:11/2011


Project Title:Quantitative Evaluation of Chemical Exchange Saturation Transfer and Diffusion Tensor Imaging at 3 Tesla MRI for detection of early degeneration in human lumbar intervertebral discs
Investigator(s):Khong PL, Anthony M, Cheung KMC, Kim M
Department:Diagnostic Radiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2010


Project Title:2010 World Molecular Imaging Congress Metabolic phenotypes of lymphomas relate to the rates of treatment response
Investigator(s):Khong PL
Department:Diagnostic Radiology
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:09/2010
Completion Date:09/2010


List of Research Outputs

Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.


Researcher : Koh YW

List of Research Outputs

Koh Y.W., Lee A.M., Lee C.P., Leung K.Y., Chan C.Y., Tang C.S.K. and Chung K.F., Identifying relationship among perceived stress, stress symptoms and related risk factors among expectant fathers during transition to fatherhood using the threat appraisal model. , Health Research Symposium. 2010.
Koh Y.W., Lee A.M., Lee C.P., Chung K.F., Chan C.Y. and Tang C.S.K., Identifying relationship between perceived stress, stress symptoms and related factors amonf expectant fathers during transition to fatherhood using the threat appraisal model: Gender role and traditionalism-modernity as moderators., Research Postgraduate Symposium. 2010.


Researcher : Kwan SH

Project Title:American Society of Human Genetics Annual Meeting 2010 Assessing statistical significance in PLINK segmental sharing test
Investigator(s):Kwan SH
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:11/2010
Completion Date:11/2010


List of Research Outputs

Kwan S.H., Kung A.W.C. and Sham P.C., A Simple Bias Correction In Linear Regression For Quantitative Trait Association Under Two-tail Extreme Selection, Behavior Genetics . 2011.
Kwan S.H., Cherny S.S. and Sham P.C., Assessing statistical significance in PLINK segmental sharing test, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2844/W, Washington, D.C., USA, November 3, 2010. 818.
Li M., Gui H., Kwan S.H. and Sham P.C., GATES: a rapid and powerful gene-based association test using extended Simes procedure., Am J Hum Genet. 2011, 88.
So H.C., Kwan S.H., Cherny S.S. and Sham P.C., Risk Prediction Of Complex Diseases From Family History And Known Susceptibility Loci, With Applications For Cancer Screening, the American Journal Of Human Genetics . 2011, 88: 548-565.


Researcher : Lam MLM

Project Title:Subjective and Objective neuropsychological and neuroanatomical abnormalities in people with high risk of developing psychosis
Investigator(s):Lam MLM, Chen EYH, Chiu CPY, Chan KW, Hui CLM
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2009
Completion Date:11/2011


List of Research Outputs

Chan K.K.S., Hui C.L.M., Lam M.L.M., Tang Y.M., Wong G.H.Y., Chan K.W. and Chen E.Y.H., A Three-year Prospective Study of Spontaneous Eye-blink Rate in First-episode Schizophrenia: Relationship with Relapse and Neurecognitive Function, East Asian Archives of Psychiatry. 2010, 20 (4): 174-179.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Tso S.S.F., Hung S.F., Chan K.P.M., Chung D.W.S., Yip K.C. and Chen E.Y.H., The Effects Of First Psychiatric Admission On 3-year Outcome In Patients With First Episode Psychosis In Hong Kong , In: 6th International Conference on Early Psychosis, Early Intervention, 7th International Conference on Early Psychosis, Early Intervention. 2010.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Wong G.H.Y., Chung D.W.S., Chan K.P.M., Hung S.F., Tso S.S.F. and Chen E.Y.H., The Initial Presentation on 3-Year Outcome in Patients with First Episode Psychosis in Hong Kong May M.L. Lam1*, Jennifer Y.M. Tang1, Christy L.M. Hui1, Cindy P.Y. Chiu1, Gloria H.Y. Wong1, C.W. Law2, Dicky W.S. Chung3, Kathy P.M. Chan4, Steve Tso5, S.F. Hung4 and Eric Y.H. Chen1, World Psychiatric Association Congress, Beijing, China 2010 Sept 1-5. 2010.
Lam M.L.M., Tang Y.M., Hui C.L.M., Yew C.W.S., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S.S.F., Wong G.H.Y., Yip K.C., Hung S.F. and Chen E.Y.H., Three-year outcome of Early Intervention Programme for Psychosis (EASY) in Hong Kong, Second Joint International Conference of The HK College of Psychiatrists and The Royal College of Psychiatrists (UK), Hong Kong2010 Dec 11-13 Brain, Behavior and Mind 2010 (BBM10)Advancing Psychiatric Care in the East . 2010.


Researcher : Lam MML

Project Title:Subjective and Objective neuropsychological and neuroanatomical abnormalities in people with high risk of developing psychosis
Investigator(s):Lam MLM, Chen EYH, Chiu CPY, Chan KW, Hui CLM
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2009
Completion Date:11/2011


List of Research Outputs

Chan K.K.S., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Chan K.W., Lam M.M.L. and Chen E.Y.H., Random number generation deficit in early schizophrenia, Perceptual and Motor Skills. 2011, 112 (1): 91-103.
Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.
Chan K.W., Chan K.S.K., Lam M.M.L., Chiu C.P.Y., Law C.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Correlate of insight in first episode psychosis : a longitudinal perspective, Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK) (December 11-13). 2010.
Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chang W.C., Hui C.L.M., Lam M.M.L., Chan K.W., Wong G.H.Y., Tang Y.M. and Chen E.Y.H., Negative symptoms and neurocognitive deficits in first-episode schizophrenia spectrum disorder. , Schizophrenia Bulletin. 2011, Vol. 37 (suppl. 1): 240.
Chen E.Y.H., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Yao T.J., Hung S.F. and Honer W.G., Maintenance therapy in patients with remitted first-episode psychosis following one year of treatment: a randomised controlled study comparing discontinuation versus quetiapine, British Medical Journal. 2010, 341: C4024.
Chiu C.P.Y., Lam M.M.L., Chan S.K., Chung D.W., Hung S.F., Tang Y.M., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Naming Psychosis: the Hong Kong experience, Early Intervention in Psychiatry. 2010, 4 (4): 270-274.
Lam M.M.L., Psychosis High Risk research-Local Scene, Medical Bulletin. 2011, 16: 18-19.
Lam M.M.L., Pearson V., Ng R.M., Chiu C.P.Y., Law C.W. and Chen E.Y.H., What does recovery from psychosis Mean? Perceptions of young first-episode patients, International Journal of Social Psychiatry. 2011, 57 (3): 248-262.
Lin J., Lam M.M.L., Chiu C., Tse M., Khong P.L., Chan C., So K.F., Chan K.W., Chang W.C. and Chen E.Y.H., The impacts of yoga and exercise on neurocognitive function and symptoms in early psychosis, Schizophrenia Bulletin. 2011, 37: 171.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.
Tang Y.M., Wong G.H.Y., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Chan K.W., Chung D.W.S., Tso S., Chan K.P.M., Yip K.C., Hung S.F. and Chen E.Y.H., Early intervention for psychosis in Hong Kong-the EASY programme, Early Intervention in Psychiatry. 2010, 4 (3): 214-219.
Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.
Wong G.H.Y., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W. and Chen E.Y.H., Understanding delusions of reference in schizophrenia: Psychopathological, cognitive, and neuroimaging explorations, Scientific Symposium of the Hong Kong Schizophrenia Research Society. 2010.
Xu J., Hui C.L.M., Wong G.H.Y., Tang Y.M., Lam M.M.L., Chiu C.P.Y. and Chen E.Y.H., Current situation and service for young people suffering from early psychosis in Hong Kong. , Journal of Youth Studies. 2011, 9-18.


Researcher : Lam SSY

Project Title:An investigation into the synergistic effect of prenatal infection and hypoxia on brain and behavioural abnormalities relevant to Schizophrenia and related neurodevelopmental disorders
Investigator(s):Lam SSY, McAlonan GM, Chua SE
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:03/2011


List of Research Outputs

Deng Y., Lam S.S.Y., Meyer U., Feldon J., Li Q., Wei R., Luk L.H.F., Chua S.E., Sham P.C., Wang Y. and McAlonan G.M., Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation, PLoS One . 2011, 6 (2): e16638.


Researcher : Law ACK

Project Title:Discovering the missing links in Alzheimer's Disease: A nouvelle, multidirectional approach
Investigator(s):Law ACK, Chu LW, Chang RCC
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2008
Completion Date:07/2010


Project Title:Linking the blood and the brain: The involvement of endothelial cell dysfunction in dementia pathogenesis.
Investigator(s):Law ACK, Vanhoutte PMGR, Chang RCC
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2010


Project Title:Intraneuronal transport defects and synaptic dysfunction: The common denominators for psychiatric disorders
Investigator(s):Law ACK, McAlonan GM, Chang RCC
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


List of Research Outputs

Cheung K.T., Leung A.Y.M., Chu D.W.S., Yung A.M.T., Wong J.G.W.S. and Law A.C.K., The Effectiveness of the Depression Care Management (DCM) Program on Diabetic and Hypertensive Patients, The 18th Annual Congress of Gerontology. 2010.
Law A.C.K., Alzheimer's disease through the eyes of a psychiatrist, Croucher Foundation Alzheimer's Disease Conference 2011: From Public Health, Basic and Clinical Sciences to Therapeutic Insights, Hong Kong, May 27, 2011.
Law A.C.K., Behavioural disturbance in dementia, TVB News interview, October 8, 2010. 2010.
Law A.C.K., Blood saves the brain: The neurovascular dimension of Alzheimer's disease, NeuroTalk 2011, Dalain, China, May 24, 2011.
Law A.C.K., 淺談老人精神科, Caritas-Happy Grannies joint sharing event. 2010.
Law A.C.K., 淺談香港老人精神健康, Changsha Psychiatric Institute. 2011.
Law A.C.K., 老人精神科簡介, Happy Grannies. 2010.
Law A.C.K., Long live the Brain: The puzzle, the work, and the direction, Frontiers in Biomedical Research HKU, Hong Kong, December 3, 2010.
Law A.C.K., Long live the brain: Can dementia be defeated by looking beyong the current "Alzheimer's disease myth"?, Hong Kong Psychogeriatric Association Mid-Year Scientific Symposium, Hong Kong, June 10, 2011.
Law A.C.K., Saying "NO" to Dementia and Other Mental Disorders, World Psychiatric Association International Congress. 2010.
Law A.C.K., 心理治療...是療心, 不是無聊!, Apple Daily. 2010.
Law A.C.K., 長者抑鬱症易被疏忽, 健康與醫療/醫學教室, Apple Daily. 2010.
Lee F.K., McAlonan G.M. and Law A.C.K., Effects of interleukin-6 on neuronal development in an in vitro maternal immune activation model, Society for Neuroscience, San Diego (November 13-17, 2010). 2010.
Wong G.T.H., Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone on cytoskeleton in dendrites and dendritic spines, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 67 P49.
Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Amyloid beta and corticosterone-mediated synaptic dysfunction, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 66 P46.
Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Chang R.C.C. and Law A.C.K., Neuroprotective role of antidepressants in amyloid and corticosterone-mediated synaptic dysfunction., The Croucher Foundation Conference: Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insights.. 2011, 29.
Wuwongse S., Hung H.L., Chang R.C.C. and Law A.C.K., The involvement of synaptic degeneration in major depressive disorder and antidepressant mechanisms of action., Society for Neuroscience 2010, San Diego, USA. 2010, 162.1/V9.
Wuwongse S., Chang R.C.C. and Law A.C.K., The putative neurodegenerative links between depression and Alzheimer's disease, Progress in Neurobiology. 2010, 91: 362-375.


Researcher : Law CW

List of Research Outputs

Chan K.W., Chan K.S.K., Lam M.M.L., Chiu C.P.Y., Law C.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Correlate of insight in first episode psychosis : a longitudinal perspective, Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK) (December 11-13). 2010.
Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chen E.Y.H., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Yao T.J., Hung S.F. and Honer W.G., Maintenance therapy in patients with remitted first-episode psychosis following one year of treatment: a randomised controlled study comparing discontinuation versus quetiapine, British Medical Journal. 2010, 341: C4024.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Tso S.S.F., Hung S.F., Chan K.P.M., Chung D.W.S., Yip K.C. and Chen E.Y.H., The Effects Of First Psychiatric Admission On 3-year Outcome In Patients With First Episode Psychosis In Hong Kong , In: 6th International Conference on Early Psychosis, Early Intervention, 7th International Conference on Early Psychosis, Early Intervention. 2010.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Wong G.H.Y., Chung D.W.S., Chan K.P.M., Hung S.F., Tso S.S.F. and Chen E.Y.H., The Initial Presentation on 3-Year Outcome in Patients with First Episode Psychosis in Hong Kong May M.L. Lam1*, Jennifer Y.M. Tang1, Christy L.M. Hui1, Cindy P.Y. Chiu1, Gloria H.Y. Wong1, C.W. Law2, Dicky W.S. Chung3, Kathy P.M. Chan4, Steve Tso5, S.F. Hung4 and Eric Y.H. Chen1, World Psychiatric Association Congress, Beijing, China 2010 Sept 1-5. 2010.
Lam M.M.L., Pearson V., Ng R.M., Chiu C.P.Y., Law C.W. and Chen E.Y.H., What does recovery from psychosis Mean? Perceptions of young first-episode patients, International Journal of Social Psychiatry. 2011, 57 (3): 248-262.


Researcher : Lee AM

Project Title:Psychosocial Group Therapy for Menopausal Women: A model for the non-pharmacological management of menopausal distress
Investigator(s):Lee AM
Department:Psychiatry
Source(s) of Funding:Centre on Behavioral Health Seed Funding Scheme - General Award
Start Date:07/2003


Project Title:Prevalence and risk factors for paternal depression and anxiety in the antenatal period
Investigator(s):Lee AM, Chung KF, Fong DYT, Law ACK, Leung KY
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:02/2009


List of Research Outputs

Chan Y.F., Leung Y.P., Fong D.Y.T., Leung C.M. and Lee A.M., Psychometric evaluation of the Hospital Anxiety and Depression Scale in a large community sample of adolescents in Hong Kong, Quality of Life Research 2010. 2010, 19 (6): 865-873.
Ho J.W.C., Hui B., Fong D.Y.T., Macfarlane D.J., Lee A.M., Leung S.S.K., Cerin E., Chan W., Leung I., Lam S., Taylor A.J. and Cheng K.K., Physical Activity Intervention in Cancer Survivors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials , NCRI conference, Liverpool, UK. 2010.
Koh Y.W., Lee A.M., Lee C.P., Leung K.Y., Chan C.Y., Tang C.S.K. and Chung K.F., Identifying relationship among perceived stress, stress symptoms and related risk factors among expectant fathers during transition to fatherhood using the threat appraisal model. , Health Research Symposium. 2010.
Koh Y.W., Lee A.M., Lee C.P., Chung K.F., Chan C.Y. and Tang C.S.K., Identifying relationship between perceived stress, stress symptoms and related factors amonf expectant fathers during transition to fatherhood using the threat appraisal model: Gender role and traditionalism-modernity as moderators., Research Postgraduate Symposium. 2010.
Lee A.M., Antenatal Emotional Disorders, RTHK Putonghua Channel. 2011.
Lee A.M., Excessive Weight Concerns Could Predispose Individuals to Eating Disorders, 都市健康小百科 第2冊, 2011.
Lee A.M., Invited Speaker for workshop entitled "Eating Disorders and Self Esteem Problems among Adolescents", Hospoital Authority-Jardines Health in Mind Youth Mental Health Promotion Programme. 2011.
Lee A.M., Premenstrual Syndrome and Menopause, 都市健康小百科 第2冊, 2011.
Lee A.M., Premenstrual Syndrome and Premenstrual Dysphoric Disorder,, RTHK Channel 1 (Ad Wiser . 2011.
Lee A.M., Premenstrual Syndrome, Sing Pao. 2011.
Lee A.M., Psychological Factors Associated with Anorexia Nervosa, Apple Daily. 2010.
Lee A.M., Chu L.W., Chong C.S., Chan S.Y., Tam S., Lam K.S.L. and Lam T.P., Relationship between symptoms of androgen deficiency and psychological factors and quality of life among Chinese men, Int J Androl. 2010, 33(5): 755-63.
Lee A.M., Reviewer for GRF, 2011.
Lee A.M., 產前焦慮影響嬰兒性情, 健康與醫療/醫學教室, Apple Daily. 2010.
Leung S.S.K., Wong D.F.K., Lam S.K., Lee A.M. and Chiang V.C.L., Efficacy of a brief cognitive behavioral intervention on pregnant women to prevent postnatal depression, 1st World Congress of Obstetric, Gynaecology, and Andrology. London, United Kingdom. 2011.
Leung S.S.K., Lee A.M., Ho J.W.C., Cheng K.K., Macfarlane D.J., Fong D.Y.T., Leung I.P.F., Lam S.H.S., Taylor A.J., Cerin E. and Chan W., Experience of lifestyle changes among colorectal cancer survivors after diagnosis and treatment., 12th Annual Evidence-Based Practice Conference, Phoenix, USA. 2011.
Leung S.S.K., Lee A.M., Ho J.W.C., Cheng K.K., Macfarlane D.J., Fong D.Y.T., Leung I.P.F., Lam S.H.S., Taylor A.J., Cerin E. and Chan W., Need assessment on lifestyle modification intervention for colorectal cancer survivors., 12th Annual Evidence-Based Practice Conference, Phoenix, USA. 2011.
Leung S.S.K., Lee A.M., Chiang V.C.L. and Ngai F.W., Work-related stress among pregnant women with depressive symptoms. , 1st World Congress of Obstetric, Gynaecology, and Andrology. London, United Kingdom.. 2011.


Researcher : Lee PWH

Project Title:A study of risk factors for exposure to AIDS in high risk adolescent Chinese females
Investigator(s):Lee PWH
Department:Psychiatry
Source(s) of Funding:Council for the AIDS Trust Fund - General Award
Start Date:04/1997


Project Title:Psychological adjustment and stresses of nurses working in acute hospital
Investigator(s):Lee PWH
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:06/1997


Project Title:The psychosocial outcomes and well-being of living related donors involved in liver transplantation surgery: a follow-up study of risk factors, resilience, and outcome predictors
Investigator(s):Lee PWH, Fan ST, Fung ASM
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:11/2003


List of Research Outputs

Kwan T.T.C., Tam K.F., Lee P.W.H., Chan K.K.L. and Ngan H.Y.S., The effect of school-based cervical cancer education on perceptions towards human papillomavirus vaccination among Hong Kong Chinese adolescent girls, Patient Education and Counselling. 2011, 84 (1): 118-122.
Lam C.L.K., Fong D.Y.T., Chin W.Y., Lee P.W.H., Lam T.P. and Lo Y.Y.C., Brief Problem-solving treatment in Primary Care (PST-PC) was not more effective than placebo for elderly patients screened-positive of psychological problems, Int J Geriatr Psychiatry. Hong Kong, 2010, 25: 968-980.
Luk K.D.K., Wan T., Wong Y.W., Cheung K.M.C., Chan Y.K., Cheng A.C.S., Kwan M.W.W., Law K.K.P., Lee P.W.H. and Cheing G.L.Y., A multidisciplinary functional resotration program for patients with chronic back pain, Seventh SICOT/SIROT Annual International Conference, Gothenburg, Sweden, August 31- September 3, 2010.
Luk K.D.K., Wan T., Wong Y.W., Cheung K.M.C., Chan Y.K., Cheng A.C.S., Kwan M.W.W., Law K.K.P., Lee P.W.H. and Cheing G.L.Y., A multidisciplinary functional restoration program for chronic back pain patietns in Hong Kong: a prospective study, Journal of Orthpaedic Surgery. 2010, 18(2): 131-138.
Luk K.D.K., Wan T.W.M., Wong Y.W., Cheung K.M.C., Chan Y.K., Cheng A.C.S., Kwan M.W.W., Law K.K.P., Lee P.W.H. and Cheing G.L.Y., A multidisciplinary rehabilitation programme for patients with chronic low back pain: a prospective study, Journal of Orthopaedic Surgery. 2010, 18 (2): 131-138.


Researcher : Lee TMC

Project Title:Selective attention biases of people with major depressive disorder, and its relationship with brain damages.
Investigator(s):Lee TMC, Leung KK
Department:Psychology
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:A post-discharge service for brain injury patients in Central and Western District
Investigator(s):Lee TMC, Chan SSC, Hung KN, Li LSW, Leung KK
Department:Psychology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:12/2006


Project Title:Cognitive Dysfunction after Anesthesia (CoDA) Study
Investigator(s):Lee TMC
Department:Psychology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2007


Project Title:Research Output Prize (Faculty of Social Sciences)
Investigator(s):Lee TMC
Department:Psychology
Source(s) of Funding:Research Output Prize (in Faculty)
Start Date:11/2007


Project Title:Effects of moods on risk-taking behavior: cognitive and neural mechanisms
Investigator(s):Lee TMC
Department:Psychology
Source(s) of Funding:Travel Grants for NSFC/RGC JRS
Start Date:12/2007


Project Title:Effects of mood on risk-taking behavior: cognitive and neural mechanisms
Investigator(s):Lee TMC
Department:Psychology
Source(s) of Funding:Matching Fund for NSFC Academic Collaboration Award
Start Date:01/2009
Completion Date:12/2010


Project Title:Effects of olfactory training on inhibition presented by people suffering from strokes
Investigator(s):Lee TMC
Department:Psychology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010
Completion Date:01/2011


Project Title:The Brain Mechanisms to Use Electronic "Bat Ears" to Replace Vision: From Human to Animal Users
Investigator(s):Lee TMC
Department:Psychology
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2010


Project Title:Memory and attention training to reduce the risk of developing dementia
Investigator(s):Lee TMC, Chu LW, Hou WK
Department:Psychology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2010


Project Title:Modality-specific neural effects of meditation
Investigator(s):Lee TMC
Department:Psychology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2011


List of Research Outputs

Xi C., Zhu Y., Niu C., Lee T.M.C., Tian Y. and Wang K., Contributions of subregions of the prefrontal cortex to the theory of mind and decision making. , Behavioural Brain Research. 2011, 22: 587-593.


Researcher : Lee YF

List of Research Outputs

Ho J.W.C., Choi S.C., Lee Y.F., Hui T.C.K., Cherny S.S., Garcia-Barcelo M.M., Carvajal-Carmona L., Liu R., To S.H., Yau T.K., Chung C.C., Yau C.C., Hui S.M., Lau P.Y., Yuen C.H., Wong Y.W., Ho S., Fung S.S., Thomlinson I.P., Houlston R.S., Cheng K.K. and Sham P.C., Replication study of SNP associations for colorectal cancer in Hong Kong Chinese, British Journal of Cancer. 2010, 104(2): 369-375.
Hysi P.G., Young T.L., Mackey D.A., Andrew T., Fernandez-Medarde A., Solouki A.M., Hewitt A.W., Macgregor S., Vingerling J.R., Li Y.J., Ikram M.K., Lee Y.F., Sham P.C., Manyes L., Porteros A., Lopes M.C., Carbonaro F., Fahy S.J., Martin N.G. and van Duijn C.M., A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25, Nature Genetics. 2010, 42 (10): 902-905.


Researcher : Lee YF

List of Research Outputs

Ho J.W.C., Choi S.C., Lee Y.F., Hui T.C.K., Cherny S.S., Garcia-Barcelo M.M., Carvajal-Carmona L., Liu R., To S.H., Yau T.K., Chung C.C., Yau C.C., Hui S.M., Lau P.Y., Yuen C.H., Wong Y.W., Ho S., Fung S.S., Thomlinson I.P., Houlston R.S., Cheng K.K. and Sham P.C., Replication study of SNP associations for colorectal cancer in Hong Kong Chinese, British Journal of Cancer. 2010, 104(2): 369-375.
Hysi P.G., Young T.L., Mackey D.A., Andrew T., Fernandez-Medarde A., Solouki A.M., Hewitt A.W., Macgregor S., Vingerling J.R., Li Y.J., Ikram M.K., Lee Y.F., Sham P.C., Manyes L., Porteros A., Lopes M.C., Carbonaro F., Fahy S.J., Martin N.G. and van Duijn C.M., A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25, Nature Genetics. 2010, 42 (10): 902-905.


Researcher : Leung MK

List of Research Outputs

Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.
Leung M.K., Cheung C., Yu K.K.K., Yip B.H.K., Sham P.C., Li Q., Chua S.E. and McAlonan G.M., Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting, Schizophrenia Bulletin. 2011, 37 (1): 199-211.
Yu K.K.K., Cheung C., Leung M.K., Li Q., Chua S.E. and McAlonan G.M., Are bipolar disorder and schizophrenia neuroanatomically distinct? An anatomical likelihood meta-analysis, Frontiers in Human Neuroscience. 2010, 26 (4): 189.


Researcher : Li M

Project Title:2010 American Society of Human Genetics Annual Meeting A powerful approach to efficiently combine p-values for gene-based association analysis
Investigator(s):Li M
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:11/2010
Completion Date:11/2010


Project Title:Development of a bioinformatics tool to optimize the experimental design of targeted next-generation sequencing studies
Investigator(s):Li M, Sham PC
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:01/2011


List of Research Outputs

Li M., Sham P.C., Cherny S.S. and Song Y., A knowledge-based weighting framework to boost the power of genome-wide association studies, PLoS One. 2010, 5 (12): e14480.
Li M., Sham P.C. and Cherny S.S., A powerful approach to efficiently combine p-values for gene-based association analysis, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2815/W, Washington, D.C., USA, November 3, 2010. 811.
Li M., Gui H., Kwan S.H. and Sham P.C., GATES: a rapid and powerful gene-based association test using extended Simes procedure., Am J Hum Genet. 2011, 88.
So H.C., Li M. and Sham P.C., Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study, Genet Epidemiol.. 2011.


Researcher : Li Q

List of Research Outputs

Chen M.O.X.I.A.N., Li Q., Rudd J.O.H.N. and Ao L. .J.U.A.N., The early the worse: effects of prenatal stress (PS) at different times of pregnancy on sensorimotor gating function. , ISPRM. 2011.
Chen M.O.X.I.A.N., Li Q., Rudd J.O.H.N., McAlonan G.M. and Ao L.I. .J.U.A.N., The time of prenatal stress exposure differentially alter behaviors in male and female offspring. , WFSBP. 2011, P-03-008.
Chen M.O.X.I.A.N., Li Q., Lu G.A.N.G., Jiu T.I.A.N., Ao L.I. .J.U.A.N., McAlonan G.M. and Rudd J.O.H.N., Time of prenatal stress challenge determines gender differences in expression of interleukin 18 in the ventral hippocampus of rats. , WFSBP. 2011, P-24-013.
Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.
Cheung C., Li Q., Wu E.X. and McAlonan G.M., Voxel-based morphometry using DARTEL in the mouse reveals differential impact of early and late prenatal inflammation on adult brain, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Deng Y., Lam S.S.Y., Meyer U., Feldon J., Li Q., Wei R., Luk L.H.F., Chua S.E., Sham P.C., Wang Y. and McAlonan G.M., Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation, PLoS One . 2011, 6 (2): e16638.
Ding A.Y., Zhou I.Y., Li Q., McAlonan G.M. and Wu E.X., DTI detection of fear conditioning induced microstructural plasticity, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Leung M.K., Cheung C., Yu K.K.K., Yip B.H.K., Sham P.C., Li Q., Chua S.E. and McAlonan G.M., Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting, Schizophrenia Bulletin. 2011, 37 (1): 199-211.
Li Q., Continuing Professional Development Grants. 2010 July, awarded. For attending Autism Diagnostic Observation Schedule (ADOS) course at the University of Cambridge Autism Research Centre., Human Resources of HKU. 2010.
Li Q., Lu G.A.N.G., Kwong W.H., CHOI H. .L.I.N.G., Zeng X. .F.E.N.G., Li Z.H.E.N., Yew D.A.V.I.D. .T. and POON W.S., Programmed neuronal cell death (PCD) induced by Immunodeficiency virus (HIV)-1 Tat and Methamphetamine (METH). , Microscopy Res. And Tech. . 2011.
McAlonan G.M., Li Q., Wu E.X. and Cheung C., A DARTEL based analysis of post-natal brain response to prenatal maternal inflammation in early or late pregnancy in the mouse, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
McAlonan G.M., Li Q. and Cheung C., The Timing and Specificity of Prenatal Immune Risk Factors for Autism Modeled in the Mouse and Relevance to Schizophrenia, Neurosignals. 2011, 18 (2): 129-139.
Wong J.A.C.K., Ng T... .B.U.N., Wang H.E.X.I.A.N.G., Sze C.W., Zhang K. .Y.A.N.B.A.O., Li Q. and Lu X. .X.U., Cordymin, an antifungal peptide from the medicinal fungus Cordyceps militaris., Phytomedicine. 2011, 18: 387-392.
Wong K.K., Li Q., McAlonan G.M. and Chan S.Y., The role of TSPYL2 in learning and memory, 15th Research Postgraduate Symposium 2010 (December 1-2, 2010). 2010.
Yu H.L., Li Q., Wang D.F., Shi L.I.N., Lu G.A.N.G., Pan F.A.N.G. and Yew D.A.V.I.D., Mapping the central effects of chronic ketamine administration in adolescent primate using functional MRI: relevance to modeling schizophrenia, Neurotoxicology. 2010, (underreviewed).
Yu K.K.K., Cheung C., Leung M.K., Li Q., Chua S.E. and McAlonan G.M., Are bipolar disorder and schizophrenia neuroanatomically distinct? An anatomical likelihood meta-analysis, Frontiers in Human Neuroscience. 2010, 26 (4): 189.
Zhou I.Y., Ding A.Y., Li Q., Fan S., Chan K.C., Cao P., Chow A.M., McAlonan G.M. and Wu E.X., Early Metabolic Changes in Hippocampus and Cingulate Cortex after Fear Conditioning, ISMRM Montreal 2011 (May 7-13, 2011). 2011.


Researcher : Lin J

List of Research Outputs

Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.


Researcher : Liu CM

List of Research Outputs

Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.


Researcher : Longenecker JM

List of Research Outputs

Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.


Researcher : Mak KY

Project Title:Program enhancement for the mental-ill patients at the S.K. Yee Mental Health Resource and Rehabilitation Centre
Investigator(s):Mak KY, Wong MMC, Mak-Lieh F, Yau EFY
Department:Psychiatry
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2000




Researcher : McAlonan GM

Project Title:King's/HKU Fellowship Awards 2008-09
Investigator(s):McAlonan GM
Department:Psychiatry
Source(s) of Funding:King's/HKU Fellowship Awards
Start Date:09/2008


Project Title:Preventing schizophrenia-like phenotype in the mouse model
Investigator(s):McAlonan GM, Chua SE, Lam SSY, Wang Y, Li Q
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010


Project Title:MRI aided diagnosis of autism
Investigator(s):McAlonan GM, Murphy DG, Cheung C, Chua SE
Department:Psychiatry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2011


Project Title:International Meeting for Autism Research 2011 A DARTEL Based Analysis of Post-Natal Brain Response to Prenatal Maternal Inflammation In Early or Late Pregnancy In the Mouse
Investigator(s):McAlonan GM
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:05/2011
Completion Date:05/2011


List of Research Outputs

Chan R.C., McAlonan G.M., Yang B., Lin L., Shum D. and Manschreck T.C., Prevalence of neurological soft signs and their neuropsychological correlates in typically developing Chinese children and Chinese children with ADHD., Development Neuropsychology. 2010, 35 (6): 698-711.
Chan R.C.K., Hu Z.Y., Cui J.F., Wang Y. and McAlonan G.M., Social attribution in children with high functioning autism and Asperger syndrome: An exploratory study in the Chinese setting, Research in Autism Spectrum Disorders. 2011, 5 (4): 1538-1548.
Chen M.O.X.I.A.N., Li Q., Rudd J.O.H.N., McAlonan G.M. and Ao L.I. .J.U.A.N., The time of prenatal stress exposure differentially alter behaviors in male and female offspring. , WFSBP. 2011, P-03-008.
Chen M.O.X.I.A.N., Li Q., Lu G.A.N.G., Jiu T.I.A.N., Ao L.I. .J.U.A.N., McAlonan G.M. and Rudd J.O.H.N., Time of prenatal stress challenge determines gender differences in expression of interleukin 18 in the ventral hippocampus of rats. , WFSBP. 2011, P-24-013.
Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.
Cheung C., Yu G.K.K., Yam A., Myint V., Chua S.E. and McAlonan G.M., Intra-orbital distance as a record of social brain dysmorphology in autism, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Cheung C., McAlonan G.M., Fung Y.Y., Fung C.M.G., Yu K.K.K., Tai K.S., Sham P.C. and Chua S.E., MRI Study of Minor Physical Anomaly in Childhood Autism Implicates Aberrant Neurodevelopment in Infancy, PLoS One. 2011, 6 (6): e20246.
Cheung C., Li Q., Wu E.X. and McAlonan G.M., Voxel-based morphometry using DARTEL in the mouse reveals differential impact of early and late prenatal inflammation on adult brain, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Chua S.E. and McAlonan G.M., Is there core diffusion tensor imaging pathology in schizophrenia?, British Journal of Psychiatry. 2010, 195: 83-87.
Deng Y., Lam S.S.Y., Meyer U., Feldon J., Li Q., Wei R., Luk L.H.F., Chua S.E., Sham P.C., Wang Y. and McAlonan G.M., Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation, PLoS One . 2011, 6 (2): e16638.
Ding A.Y., Zhou I.Y., Li Q., McAlonan G.M. and Wu E.X., DTI detection of fear conditioning induced microstructural plasticity, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Lee F.K., McAlonan G.M. and Law A.C.K., Effects of interleukin-6 on neuronal development in an in vitro maternal immune activation model, Society for Neuroscience, San Diego (November 13-17, 2010). 2010.
Leung M.K., Cheung C., Yu K.K.K., Yip B.H.K., Sham P.C., Li Q., Chua S.E. and McAlonan G.M., Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting, Schizophrenia Bulletin. 2011, 37 (1): 199-211.
Li H.J., Chan R.C.K., McAlonan G.M. and Gong Q.Y., Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data, Schizophrenia Bulletin. 2010, 36 (5): 1029-1039.
McAlonan G.M., Li Q., Wu E.X. and Cheung C., A DARTEL based analysis of post-natal brain response to prenatal maternal inflammation in early or late pregnancy in the mouse, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
McAlonan G.M., Chairing session: "Brain Imaging and Neuropsychology of Typical and Atypical Development", 7th International Conference on Cognitive Science (ICCS). Section 3, August 17-20, 2010, Beijing, China. 2010.
McAlonan G.M., Invited Speaker for lecture entitled "MRI as a translational tool in autism research", 7th International Conference on Cognitive Science (ICCS). Section 2, Symposium 3. p126, August 17-20, 2010, Beijing, China. 2010.
McAlonan G.M., Li Q. and Cheung C., The Timing and Specificity of Prenatal Immune Risk Factors for Autism Modeled in the Mouse and Relevance to Schizophrenia, Neurosignals. 2011, 18 (2): 129-139.
McAlonan G.M., 你對自閉人士知多少?, 健康與醫療/醫療教室, Apple Daily, 2010. 2010.
Meyer U., Weiner I. and McAlonan G.M., The neuropathological contribution of prenatal inflammation to schizophrenia, Expert Review of Neurotherapeutics. 2011, 11 (1): 29.
Wang Q., Deng W., Huang C., Li M., Ma X., Wang Y., Jiang L., Lui S., Huang X., Chua S.E., Cheung C., McAlonan G.M., Sham P.C., Murray R.M., Collier D.A., Gong Q. and Li T., Abnormalities in connectivity of white-matter tracts in patients with familial and non-familial schizophrenia., Psychological Medicine. 2010, 41 (8): 1691-1700.
Wong C., Yu G.K.K., Chua S.E., Cheung C. and McAlonan G.M., Do Autism Spectrum Disorders and Bipolar Disorder share a neuroanatomical phenotype?, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
Wong K.K., Li Q., Wong H.T., Tsang K.H., Lai S.K., McAlonan G.M., Chan Y.S. and Chan S.Y., TSPYL2 regulates CREB-Dependent Gene Expression, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2079.
Wong K.K., Li Q., McAlonan G.M. and Chan S.Y., The role of TSPYL2 in learning and memory, 15th Research Postgraduate Symposium 2010 (December 1-2, 2010). 2010.
Yu G.K.K., Pun E., Wong P., Chua S.E., Cheung C. and McAlonan G.M., Do Autism Spectrum Disorders and Obsessive Compulsive Disorders share a neuroanatomical phenotype?, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
Yu G.K.K., Cheung C., Fung Y.Y., Fung G., McAlonan G.M. and Chua S.E., MRI brain scan study of minor physical anomalies in autism, Autism 2010 - Geneva Centre for Autism's International Symposium (November 3-5, 2010). 2010.
Yu K.K.K., Cheung C., Leung M.K., Li Q., Chua S.E. and McAlonan G.M., Are bipolar disorder and schizophrenia neuroanatomically distinct? An anatomical likelihood meta-analysis, Frontiers in Human Neuroscience. 2010, 26 (4): 189.
Yu K.K.K., Cheung C., Chua S.E. and McAlonan G.M., Can Asperger syndrome be distinguished from autism? An anatomic likelihood meta-analysis of MRI studies, Journal of Psychiatry and Neuroscience. 2011, 36 (2).
Zhang Z., Tan Q.R., Tong Y., Wang X.Y., Wang H.H., Ho L.M., Wong H.K., Feng Y., Wang D., Ng R., McAlonan G.M., Wang C.Y. and Wong V.T., An Epidemiological Study of Concomitant Use of Chinese Medicine and Antipsychotics in Schizophrenic Patients: Implication for Herb-Drug Interaction, PLos One. 2011, 6 (2): e17239.
Zhou I.Y., Ding A.Y., Li Q., Fan S., Chan K.C., Cao P., Chow A.M., McAlonan G.M. and Wu E.X., Early Metabolic Changes in Hippocampus and Cingulate Cortex after Fear Conditioning, ISMRM Montreal 2011 (May 7-13, 2011). 2011.


Researcher : Ng ML

Project Title:Chaos in psychotherapy
Investigator(s):Ng ML
Department:Psychiatry
Source(s) of Funding:Department of Psychiatry - General Award
Start Date:09/1998
Completion Date:08/2010


Project Title:Violence on male genitalia - a ten year review of cases in Hong Kong
Investigator(s):Ng ML
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:05/2002




Researcher : Poon MK

List of Research Outputs

Poon M.K., Chung K.F. and Yeung W.F., Classification of Insomnia Using Traditional Chinese Medicine (TCM) Diagnostic System: A Systematic Review, Hong Kong International Acupuncture Conference: Neurological and Mental Illness. 2011.
Yeung W.F., Chung K.F. and Poon M.K., Acupuncture and Chinese Herbal Medicine for Insomnia: A Systematic Review of Effectiveness and TCM Pattern Differentiation, Hong Kong International Acupuncture Conference: Neurological and Mental Illness. 2011.


Researcher : Sham PC

Project Title:Replication study of susceptibility genes for colorectal cancer
Investigator(s):Sham PC, Ho JWC, Cheng KK
Department:Medical Faculty
Source(s) of Funding:Small Project Funding
Start Date:10/2007


Project Title:Genome-wide association study of schizophrenia
Investigator(s):Sham PC, Chen EYH, Chen RYL, Cherny SS, Tam PKH
Department:Medical Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2008


Project Title:Genomics
Investigator(s):Sham PC
Department:Medical Faculty
Source(s) of Funding:Seed Funding for Strategic Research Theme
Start Date:06/2008
Completion Date:05/2011


Project Title:Visiting Research Professors Scheme 2009-10
Investigator(s):Sham PC
Department:Medical Faculty
Source(s) of Funding:Visiting Research Professors Scheme
Start Date:09/2009


Project Title:To determine the functional variants of candidate genes identified by Genome-wide Association Study of Osteoporosis
Investigator(s):Sham PC, Gao RY, Xiao S, Kung AWC
Department:Medical Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2010


Project Title:Genetic studies of endophenotypes for psychosis
Investigator(s):Sham PC
Department:Medical Faculty
Source(s) of Funding:Small Project Funding
Start Date:10/2010


Project Title:60th Annual Meeting of the American Society of Human Genetics (ASHG) Using functional information to re-prioritize GWAS hits (Invited talk)
Investigator(s):Sham PC
Department:Medical Faculty
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:11/2010
Completion Date:11/2010


List of Research Outputs

Burchard J., Zhang C., Liu A.M.L., Poon R.T.P., Lee N.P.Y., Wong K.F., Sham P.C., Lam B.Y., Ferguson M.D., Tokiwa G., Smith R., Leeson B., Beard R., Lamb J.R., Lim L., Mao M., Dai H. and Luk J.M.C., MicroRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma, Molecular Systems Biology. 2010, 6: 402.
Campbell D.D., Sham P.C., Knight J., Wickham H. and Landau S., Software for Generating Liability Distributions for Pedigrees Conditional on Their Observed Disease States and Covariates, Genetic Epidemiology. 2010, 34 (2): 159-170.
Carroll L.S., Williams N.M., Moskvina V., Russell E., Norton N., Williams H.J., Peirce T., Georgieva L., Dwyer S., Grozeva D., Greene E., Farmer A., McGuffin P., Morris D.W., Corvin A., Gill M., Rujescu D., Sham P.C., Holmans P., Jones I., Kirov G., Craddock N., O'Donovan M.C. and Owen M.J., Evidence for rare and common genetic risk variants for schizophrenia at protein kinase C, alpha, Molecular Psychiatry. 2010, 15 (11): 1011-1111.
Chan R.C.K., Gottesman I.I., Ge X.J. and Sham P.C., Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: a potential databank from China, Frontiers in Human Neuroscience. 2010, 4.
Chan Y.K., Xu M., Ching J.C.Y., Chan V.S.F., Ip Y.C., Yam L., Chu C.M., Lai S.T., So K.M., Wong T.Y., Chung P.H., Tam P., Yip S.P., Sham P.C., Lin C., Leung G.M., Peiris J.S.M. and Khoo U.S., Association of a single nucleotide polymorphism in the CD209 (DC-SIGN) promoter with SARS severity, Hong Kong Med J. 2010, 16(5 Suppl 4): 37-42.
Chan Y.K., Xu M.S., Ching C.Y.J., So T.M., Lai S.T., Chu C.M., Yam L.Y., Wong A.T., Chung P.H., Chan V.S.F., Lin C.L., Sham P.C., Leung G.M., Peiris J.S.M. and Khoo U.S., CD209 (DC-SIGN) -336A>G promoter polymorphism and severe acute respiratory syndrome in Hong Kong Chinese, Hum Immunol. 2010, 71(7): 702-7.
Cherny S.S., Guo Y., Sham P.C., Baum L. and Kwan P., A genome-wide association study of symptomatic epilepsy in Han Chinese detects multiple variants, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2638/F, Washington, D.C., USA, November 5, 2010. 764.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Association of a genetic variant in adrenomedullin gene with its plasma level , Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Gamma-glutamyl transaminase level predicts the development of hypertension., Poster Presentation at the 23rd Scientific Meeting of the International Society of Hypertension, Vancouver. 2010.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Gamma-glutamyl transferase level predicts the development of hypertension in Hong Kong Chinese, Clin Chim Acta. 2011, 412(15-16): 1326-1331.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Gamma-glutamyl transferase level predicts the development of hypertension in Hong Kong Chinese, Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Thomas G.N., Lam T.H. and Lam K.S.L., Mendelian randomisation analysis suggests that plasma interleukin-6 is raised in hypertension but does not cause its development, Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Plasma adrenomedullin level is related to plasma interleukin-6 and a polymorphism in the adrenomedullin gene, Basic & Clinical Pharmacology & Toxicology. Presented at the 10th Congress of the European Association for Clinical Pharmacology and Therapeutics, Budapest. 2011, 109 (Suppl. 1): 102-103.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Role of genetic variants in gene encoding lipocalin-2 in the development of elevated blood pressure, Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Lam K.S.L., Cherny S.S. and Sham P.C., Using glycosylated haemoglobin to define the metabolic syndrome in United States adults, Presented at the 16th Medical Research Conference of the Department of Medicine, The University of Hong Kong, Hong Kong. 2011.
Cheung B.M.Y., Ong K.L., Tso A.W.K., Lam K.S.L., Cherny S.S. and Sham P.C., Using glycosylated hemoglobin to define the metabolic syndrome in United States adults. , Oral Presentation at the 23rd Scientific Meeting of the International Society of Hypertension, Vancouver. 2010.
Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.
Cheung C., McAlonan G.M., Fung Y.Y., Fung C.M.G., Yu K.K.K., Tai K.S., Sham P.C. and Chua S.E., MRI Study of Minor Physical Anomaly in Childhood Autism Implicates Aberrant Neurodevelopment in Infancy, PLoS One. 2011, 6 (6): e20246.
Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.
Deng Y., Lam S.S.Y., Meyer U., Feldon J., Li Q., Wei R., Luk L.H.F., Chua S.E., Sham P.C., Wang Y. and McAlonan G.M., Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation, PLoS One . 2011, 6 (2): e16638.
Fan Y., Cheung K.M.C., Chan D., Cheung W.Y., Cheah K.S.E., Sham P.C., Luk K.D.K. and Song Y., Gemome-Wide Association Study of Adolescent Idiopathic Scoliosis in Southern Chinese, 15th Research Postgraduate Symposium, HKU, Dec 1 & 2, 2010. HK.
Fan Y., Cheung K.M.C., Chan D., Cheung W.Y., Cheah K.S.E., Sham P.C., Luk K.D.K. and Song Y., Genome-wide association study of adolescent idiopathic scoliosis in Southern China, 12th International Phillip Zorab Symposium, London, UK, March 16-18, 2011.
Fan Y., Cheung K.M.C., Chan D., Cheung W.Y., Cheah K.S.E., Sham P.C., Luk K.D.K. and Song Y., Genome-wide association study of adolescent idiopathic scoliosis in southern China, 12th International Phillip Zorab Symposium, 2011 . 2011.
Garcia-Barcelo M.M., Tang C., Tang W.K., So M.T., Sham P.C., Cherny S.S. and Tam P.H., Fine mapping of the NRG1 Hirschsprungs-associated gene, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 1155/F, Washington, D.C., USA, November 5, 2010. 361.
Garcia-Barcelo M.M., Miao X.P., Tang S.M., So H.C., Tang W.K., Leon T.Y.Y., So M.T., Yip B.H.K., Chen R.Y.L., Cheung E.F.C., Chen E.Y.H., Li T., Tam P.K.H., Cherny S.S. and Sham P.C., No NRG1 V266L in Chinese patients with schizophrenia, Psychiatric Genetics. 2011, 21 (1): 47-49.
Ho J.W.C., Choi S.C., Lee Y.F., Hui T.C.K., Cherny S.S., Garcia-Barcelo M.M., Carvajal-Carmona L., Liu R., To S.H., Yau T.K., Chung C.C., Yau C.C., Hui S.M., Lau P.Y., Yuen C.H., Wong Y.W., Ho S., Fung S.S., Thomlinson I.P., Houlston R.S., Cheng K.K. and Sham P.C., Replication study of SNP associations for colorectal cancer in Hong Kong Chinese, British Journal of Cancer. 2010, 104(2): 369-375.
Hysi P.G., Young T.L., Mackey D.A., Andrew T., Fernandez-Medarde A., Solouki A.M., Hewitt A.W., Macgregor S., Vingerling J.R., Li Y.J., Ikram M.K., Lee Y.F., Sham P.C., Manyes L., Porteros A., Lopes M.C., Carbonaro F., Fahy S.J., Martin N.G. and van Duijn C.M., A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25, Nature Genetics. 2010, 42 (10): 902-905.
Khoo U.S., Ching J.C.Y., Chan Y.K., Xu M., So K.M., Lai S.T., Chu C.M., Yam L., Wong T.Y., Chung P.H., Chan V.S.F., Tam P.K.H., Yip S.P., Lin C.L., Sham P.C., Leung G.M. and Peiris J.S.M., The CD209 (DC-SIGN) -336A>G and MxA -123C>A promoter polymorphisms in Severe Acute Respiratory Syndrome Coronavirus infection in Hong Kong Chinese, Health Research Symposium 2010: “Improving health and recognising excellence, Hong Kong. 2010.
Kwan S.H., Cherny S.S. and Sham P.C., Assessing statistical significance in PLINK segmental sharing test, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2844/W, Washington, D.C., USA, November 3, 2010. 818.
Leung M.K., Cheung C., Yu K.K.K., Yip B.H.K., Sham P.C., Li Q., Chua S.E. and McAlonan G.M., Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting, Schizophrenia Bulletin. 2011, 37 (1): 199-211.
Li H.Y., Cheung C.L., Xiao S., Lau K.S., Gao Y., Bow C.H.Y., Huang Q.Y., Sham P.C. and Kung A.W.C., Identification Of Qtl Genes For Bmd Variation Using Both Linkage And Gene-based Association Approaches., Human Genetics. 2011.
Li M., Jiang L., Kao P.Y.P., Sham P.C. and Song Y., A knowledge-based weighting approach to boost power of genome-wide association studies., PlosOne. 2010, 5(12): e14480.
Li M., Sham P.C., Cherny S.S. and Song Y., A knowledge-based weighting framework to boost the power of genome-wide association studies, PLoS One. 2010, 5 (12): e14480.
Li M., Sham P.C. and Cherny S.S., A powerful approach to efficiently combine p-values for gene-based association analysis, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2815/W, Washington, D.C., USA, November 3, 2010. 811.
Li M., Gui H., Kwan S.H. and Sham P.C., GATES: a rapid and powerful gene-based association test using extended Simes procedure., Am J Hum Genet. 2011, 88.
Li M.J., Sham P.C. and Wang J., FastPval: a fast and memory efficient program to calculate very low P-values from empirical distribution, Bioinformatics. 2010, 26 (22): 2897-2899.
Ong K.L., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Lam T.H., Cheung B.M.Y. and Lam K.S.L., A genetic variant in the gene encoding adrenomedullin predicts the development of dysglycemia over 6.4 years in Chinese, Clin Chim Acta. 2010, 412: 353-7.
Ong K.L., Cheung B.M.Y., Tso A.W.K., Leung Y.H., Cherny S.S., Sham P.C., Lam T.H. and Lam K.S.L., Association of a genetic variant in adrenomedullin gene with its plasma level., Oral Presentation at the Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction, Hong Kong. 2010.
Ong K.L., Li M., Tso A.W.K., Xu A., Cherny S.S., Sham P.C., Tse H.F., Lam T.H., Cheung B.M.Y. and Lam K.S.L., Association of genetic variants in the adiponectin gene with adiponectin level and hypertension in Hong Kong Chinese. , European Journal of Endocrinology. 2010, 163: 251-257.
Sham P.C., Enabling Technologies, PUMC-HKU Joint Symposium, Shenzhen, May 6, 2011.
Sham P.C., From GWAS to Risk Prediction, Asia-Pacific Conference of Human Genetics, Hong Kong. December 1, 2010.
Sham P.C., From GWAS to Risk Prediction, HK-UK Joint International Psychiatry Conference, Hong Kong, December 12, 2010.
Sham P.C., From Risk Predication to Rare Variant Analysis of Complex Diseases , Nature Genetics - Anhui Medical College GWAS Workshop, Hefei, May 22, 2011.
Sham P.C., GWAS: Pathways / Networks / Multilocus Analyses, The 2011 International Workshop on Statistical Methodology for Human Genomic Studies, March 9, 2011.
Sham P.C. and Cherny S.S., Genetic architecture of complex diseases. In E Zeggini and A Morris (eds), Analysis of Complex Disease Association Studies: A Practical Guide. Elsevier, Oxford, 2010, 1-13.
Sham P.C., Identification of Disease Genes - Technology and Strategies, Colloquium on Genome Research, Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, October 14, 2010.
Sham P.C., Introduction to Genetic and Statistics, The 2011 International Workshop on Statistical Methodology for Human Genomic Studies, March 7, 2011.
Sham P.C., Power Considerations, Cold Spring Harbor Laboratory Workshop on Genetics of Complex Diseases. July 9, 2010.
Sham P.C., Prospects for Genetic Research on Bipolar Affective Disorders, Hong Kong and Macau Bipolar Forum, Guangdong, Guangzhou, February, 2011.
Sham P.C., Prospects for Genetic Risk Prediction for Complex Diseases, HKU-NHRI Joint Symposium, Taiwan, March 29, 2011.
Sham P.C., Statistical Issues in Endophenotype Research, Endophenotype Strategy for Psychotic Disorders and Summit Meeting of State Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, October 11, 2010.
Sham P.C., Using functional annotation to reprioritize GWAS hits, American Society of Human Genetics Annual Meeting, Wasington. November 6, 2010.
So H.C. and Sham P.C., A Unifying Framework for Evaluating the Predictive Power of Genetic Variants Based on the Level of Heritability Explained, PLoS Genetics. 2010, 6 (12): e1001230.
So H.C. and Sham P.C., Effect Size Measures in Genetic Association Studies and Age-Conditional Risk Prediction, Human Heredity. 2010, 70 (3): 205-218.
So H.C., Yip B.H.K. and Sham P.C., Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies, PLoS One. 2010, 5 (11): e13898.
So H.C., Gui H., Cherny S.S. and Sham P.C., Evaluating the Heritability Explained by Known Susceptibility Variants: A Survey of Ten Complex Diseases, Genetic Epidemiology. 2011, 35 (5): 310-317.
So H.C. and Sham P.C., Multiple Testing and Power Calculations in Genetic Association Studies, Cold Spring Harb Protoc. 2011, pdb top95.
So H.C. and Sham P.C., Robust Association Tests Under Different Genetic Models, Allowing for Binary or Quantitative Traits and Covariates, Behavior Genetics. 2011.
So H.C., Li M. and Sham P.C., Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study, Genet Epidemiol.. 2011.
Tang S.M., Tang W.K., So M.T., Miao X., Leung M.C., Yip B.H.K., Leon Y.Y., Ngan E.S.W., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wu X.Z., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Fine mapping of the NRG1 Hirschsprung's disease locus, PLoS One. 2011, 6(1): e16181.
Toulopoulou T., Goldberg T.E., Rebollo Mesa I., Picchioni M., Rijsdijk F., Stahl D., Cherny S.S., Sham P.C., Faraone S.V., Tsuang M., Weinberger D.R., Seidman L.J. and Murray R.M., Impaired Intellect and Memory: A Missing Link Between Genetic Risk and Schizophrenia?, Archives of General Psychiatry. 2010, 67 (9): 905-913.
Wang Q., Deng W., Huang C., Li M., Ma X., Wang Y., Jiang L., Lui S., Huang X., Chua S.E., Cheung C., McAlonan G.M., Sham P.C., Murray R.M., Collier D.A., Gong Q. and Li T., Abnormalities in connectivity of white-matter tracts in patients with familial and non-familial schizophrenia., Psychological Medicine. 2010, 41 (8): 1691-1700.
Wong E.H.M., Tang S.M., Garcia-Barcelo M.M., Zhang X.J., Liu J.J., Cherny S.S., Sham P.C. and Tam P.K.H., Genomi-wide association study on anorectal malformations in the Chinese population, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2942/T, Washington, D.C., USA, November 5, 2010. 846.
Xiao S., Cherny S.S., Li H.Y., Gao Y., Tso H.W., Lau K.S., Luk K.D.K., Sham P.C. and Kung A.W.C., Association Of Jag1 Gene And Its Variant Sequence With Bone Mineral Density And Osteoporotic Fractures: A Genome-wide Association Study And Follow-up Replication Studies, The HKSEMR Annual Scientific Meeting and Annual General Meeting, 21 November, Hong Kong. 2010.
Xiao S., Gao Y., Cheung C.L., Bow C.H.Y., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Association of Cdx1 Binding Site of Periostin Gene with Bone Mineral Density and Vertebral Fracture Risk, The 3rd Joint Meeting of the European Calcified Tissue Society and the International Bone and Mineral Society, 7-11 MAY, Athens, Greece. Athens, Greece, 2011, 7-11 MAY.
Xu M.Q., Sham P.C., Ye Z., Lindpaintner K. and He L., A1166C genetic variation of the angiotensin II type I receptor gene and susceptibility to coronary heart disease: Collaborative of 53 studies with 20,435 cases and 23,674 controls, Atherosclerosis. 2010, 213 (1): 191-199.
Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607.
Yip S.P., Leung K.H., Fung W.Y., Ng P.W., Sham P.C. and Yap M.K.H., A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population, Molecular Vision. 2011, 17 (91-92): 810-821.
Zhang L., Yang W., Ying D., Cherny S.S., Hildebrandt F., Sham P.C. and Lau Y.L., Homozygosity Mapping on a Single Patient-Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data, Human Mutation. 2011, 32 (3): 345-353.
Zhang X.W., Cherny S.S., Huang Y., Gao X., Xiang Y., Fu Y.X., Meng H.Q., Ma X.H., Wang Y.C., Li T. and Sham P.C., Effect of parental age on children's intelligence in the Southwestern China Prospective twin registry, Behavior Genetics. 2010, 40 (6): 820.
Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234.


Researcher : So HC

List of Research Outputs

Garcia-Barcelo M.M., Miao X.P., Tang S.M., So H.C., Tang W.K., Leon T.Y.Y., So M.T., Yip B.H.K., Chen R.Y.L., Cheung E.F.C., Chen E.Y.H., Li T., Tam P.K.H., Cherny S.S. and Sham P.C., No NRG1 V266L in Chinese patients with schizophrenia, Psychiatric Genetics. 2011, 21 (1): 47-49.
So H.C. and Sham P.C., A Unifying Framework for Evaluating the Predictive Power of Genetic Variants Based on the Level of Heritability Explained, PLoS Genetics. 2010, 6 (12): e1001230.
So H.C. and Sham P.C., Effect Size Measures in Genetic Association Studies and Age-Conditional Risk Prediction, Human Heredity. 2010, 70 (3): 205-218.
So H.C., Yip B.H.K. and Sham P.C., Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies, PLoS One. 2010, 5 (11): e13898.
So H.C., Gui H., Cherny S.S. and Sham P.C., Evaluating the Heritability Explained by Known Susceptibility Variants: A Survey of Ten Complex Diseases, Genetic Epidemiology. 2011, 35 (5): 310-317.
So H.C. and Sham P.C., Multiple Testing and Power Calculations in Genetic Association Studies, Cold Spring Harb Protoc. 2011, pdb top95.
So H.C., Kwan S.H., Cherny S.S. and Sham P.C., Risk Prediction Of Complex Diseases From Family History And Known Susceptibility Loci, With Applications For Cancer Screening, the American Journal Of Human Genetics . 2011, 88: 548-565.
So H.C. and Sham P.C., Robust Association Tests Under Different Genetic Models, Allowing for Binary or Quantitative Traits and Covariates, Behavior Genetics. 2011.
So H.C., Li M. and Sham P.C., Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study, Genet Epidemiol.. 2011.


Researcher : Song Y

List of Research Outputs

Chu L.W., Tam S., Wong L.C., Yik P.Y., Song Y., Cheung B.M.Y., Morley J.E. and Lam K.S.L., Bioavailable Testosterone Predicts a Lower Risk of Alzheimer's Disease in Older Men, J Alzheimers Dis. 2010, 21(4): 1335-1345.
Li M., Sham P.C., Cherny S.S. and Song Y., A knowledge-based weighting framework to boost the power of genome-wide association studies, PLoS One. 2010, 5 (12): e14480.


Researcher : Song Y

List of Research Outputs

Chu L.W., Tam S., Wong L.C., Yik P.Y., Song Y., Cheung B.M.Y., Morley J.E. and Lam K.S.L., Bioavailable Testosterone Predicts a Lower Risk of Alzheimer's Disease in Older Men, J Alzheimers Dis. 2010, 21(4): 1335-1345.
Li M., Sham P.C., Cherny S.S. and Song Y., A knowledge-based weighting framework to boost the power of genome-wide association studies, PLoS One. 2010, 5 (12): e14480.


Researcher : Tai KS

List of Research Outputs

Cheung V., Chiu C.P.Y., Law C.W., Cheung C., Hui C.L.M., Chan K.K.S., Sham P.C., Deng Y., Tai K.S., Khong P.L., McAlonan G.M., Chua S.E. and Chen E.Y.H., Positive symptoms and white matter microstructure in never-medicated first episode schizophrenia., Psychological Medicine. 2010, 1: 1-11.


Researcher : Tang SM

List of Research Outputs

Garcia-Barcelo M.M., Miao X.P., Tang S.M., So H.C., Tang W.K., Leon T.Y.Y., So M.T., Yip B.H.K., Chen R.Y.L., Cheung E.F.C., Chen E.Y.H., Li T., Tam P.K.H., Cherny S.S. and Sham P.C., No NRG1 V266L in Chinese patients with schizophrenia, Psychiatric Genetics. 2011, 21 (1): 47-49.
Wong E.H.M., Tang S.M., Garcia-Barcelo M.M., Zhang X.J., Liu J.J., Cherny S.S., Sham P.C. and Tam P.K.H., Genomi-wide association study on anorectal malformations in the Chinese population, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2942/T, Washington, D.C., USA, November 5, 2010. 846.


Researcher : Tang YM

List of Research Outputs

Chan K.K.S., Hui C.L.M., Lam M.L.M., Tang Y.M., Wong G.H.Y., Chan K.W. and Chen E.Y.H., A Three-year Prospective Study of Spontaneous Eye-blink Rate in First-episode Schizophrenia: Relationship with Relapse and Neurecognitive Function, East Asian Archives of Psychiatry. 2010, 20 (4): 174-179.
Chan K.K.S., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Chan K.W., Lam M.M.L. and Chen E.Y.H., Random number generation deficit in early schizophrenia, Perceptual and Motor Skills. 2011, 112 (1): 91-103.
Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.
Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chang W.C., Hui C.L.M., Lam M.M.L., Chan K.W., Wong G.H.Y., Tang Y.M. and Chen E.Y.H., Negative symptoms and neurocognitive deficits in first-episode schizophrenia spectrum disorder. , Schizophrenia Bulletin. 2011, Vol. 37 (suppl. 1): 240.
Chiu C.P.Y., Lam M.M.L., Chan S.K., Chung D.W., Hung S.F., Tang Y.M., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Naming Psychosis: the Hong Kong experience, Early Intervention in Psychiatry. 2010, 4 (4): 270-274.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Tso S.S.F., Hung S.F., Chan K.P.M., Chung D.W.S., Yip K.C. and Chen E.Y.H., The Effects Of First Psychiatric Admission On 3-year Outcome In Patients With First Episode Psychosis In Hong Kong , In: 6th International Conference on Early Psychosis, Early Intervention, 7th International Conference on Early Psychosis, Early Intervention. 2010.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Wong G.H.Y., Chung D.W.S., Chan K.P.M., Hung S.F., Tso S.S.F. and Chen E.Y.H., The Initial Presentation on 3-Year Outcome in Patients with First Episode Psychosis in Hong Kong May M.L. Lam1*, Jennifer Y.M. Tang1, Christy L.M. Hui1, Cindy P.Y. Chiu1, Gloria H.Y. Wong1, C.W. Law2, Dicky W.S. Chung3, Kathy P.M. Chan4, Steve Tso5, S.F. Hung4 and Eric Y.H. Chen1, World Psychiatric Association Congress, Beijing, China 2010 Sept 1-5. 2010.
Lam M.L.M., Tang Y.M., Hui C.L.M., Yew C.W.S., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S.S.F., Wong G.H.Y., Yip K.C., Hung S.F. and Chen E.Y.H., Three-year outcome of Early Intervention Programme for Psychosis (EASY) in Hong Kong, Second Joint International Conference of The HK College of Psychiatrists and The Royal College of Psychiatrists (UK), Hong Kong2010 Dec 11-13 Brain, Behavior and Mind 2010 (BBM10)Advancing Psychiatric Care in the East . 2010.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.
Tang Y.M., Wong G.H.Y., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Chan K.W., Chung D.W.S., Tso S., Chan K.P.M., Yip K.C., Hung S.F. and Chen E.Y.H., Early intervention for psychosis in Hong Kong-the EASY programme, Early Intervention in Psychiatry. 2010, 4 (3): 214-219.
Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.
Wong G.H.Y., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W. and Chen E.Y.H., Understanding delusions of reference in schizophrenia: Psychopathological, cognitive, and neuroimaging explorations, Scientific Symposium of the Hong Kong Schizophrenia Research Society. 2010.
Xu J., Hui C.L.M., Wong G.H.Y., Tang Y.M., Lam M.M.L., Chiu C.P.Y. and Chen E.Y.H., Current situation and service for young people suffering from early psychosis in Hong Kong. , Journal of Youth Studies. 2011, 9-18.


Researcher : Tang YM

List of Research Outputs

Chan K.K.S., Hui C.L.M., Lam M.L.M., Tang Y.M., Wong G.H.Y., Chan K.W. and Chen E.Y.H., A Three-year Prospective Study of Spontaneous Eye-blink Rate in First-episode Schizophrenia: Relationship with Relapse and Neurecognitive Function, East Asian Archives of Psychiatry. 2010, 20 (4): 174-179.
Chan K.K.S., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Chan K.W., Lam M.M.L. and Chen E.Y.H., Random number generation deficit in early schizophrenia, Perceptual and Motor Skills. 2011, 112 (1): 91-103.
Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.
Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chang W.C., Hui C.L.M., Lam M.M.L., Chan K.W., Wong G.H.Y., Tang Y.M. and Chen E.Y.H., Negative symptoms and neurocognitive deficits in first-episode schizophrenia spectrum disorder. , Schizophrenia Bulletin. 2011, Vol. 37 (suppl. 1): 240.
Chiu C.P.Y., Lam M.M.L., Chan S.K., Chung D.W., Hung S.F., Tang Y.M., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Naming Psychosis: the Hong Kong experience, Early Intervention in Psychiatry. 2010, 4 (4): 270-274.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Tso S.S.F., Hung S.F., Chan K.P.M., Chung D.W.S., Yip K.C. and Chen E.Y.H., The Effects Of First Psychiatric Admission On 3-year Outcome In Patients With First Episode Psychosis In Hong Kong , In: 6th International Conference on Early Psychosis, Early Intervention, 7th International Conference on Early Psychosis, Early Intervention. 2010.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Wong G.H.Y., Chung D.W.S., Chan K.P.M., Hung S.F., Tso S.S.F. and Chen E.Y.H., The Initial Presentation on 3-Year Outcome in Patients with First Episode Psychosis in Hong Kong May M.L. Lam1*, Jennifer Y.M. Tang1, Christy L.M. Hui1, Cindy P.Y. Chiu1, Gloria H.Y. Wong1, C.W. Law2, Dicky W.S. Chung3, Kathy P.M. Chan4, Steve Tso5, S.F. Hung4 and Eric Y.H. Chen1, World Psychiatric Association Congress, Beijing, China 2010 Sept 1-5. 2010.
Lam M.L.M., Tang Y.M., Hui C.L.M., Yew C.W.S., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S.S.F., Wong G.H.Y., Yip K.C., Hung S.F. and Chen E.Y.H., Three-year outcome of Early Intervention Programme for Psychosis (EASY) in Hong Kong, Second Joint International Conference of The HK College of Psychiatrists and The Royal College of Psychiatrists (UK), Hong Kong2010 Dec 11-13 Brain, Behavior and Mind 2010 (BBM10)Advancing Psychiatric Care in the East . 2010.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.
Tang Y.M., Wong G.H.Y., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Chan K.W., Chung D.W.S., Tso S., Chan K.P.M., Yip K.C., Hung S.F. and Chen E.Y.H., Early intervention for psychosis in Hong Kong-the EASY programme, Early Intervention in Psychiatry. 2010, 4 (3): 214-219.
Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.
Wong G.H.Y., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W. and Chen E.Y.H., Understanding delusions of reference in schizophrenia: Psychopathological, cognitive, and neuroimaging explorations, Scientific Symposium of the Hong Kong Schizophrenia Research Society. 2010.
Xu J., Hui C.L.M., Wong G.H.Y., Tang Y.M., Lam M.M.L., Chiu C.P.Y. and Chen E.Y.H., Current situation and service for young people suffering from early psychosis in Hong Kong. , Journal of Youth Studies. 2011, 9-18.


Researcher : Tso KC

List of Research Outputs

Chung K.F. and Tso K.C., Assessing pain in depression: What do ratings on unidimensional pain scales really mean?, Comprehensive Psychiatry. 2011, 52 (2): 208-217.
Chung K.F., Tso K.C., Yeung W.F. and Li W.H., Quality of life in major depressive disorder: the role of pain and pain catastrophizing cognition., Comprehensive Psychiatry. 2011, [Epub ahead of print].
Chung K.F. and Tso K.C., Relationship between insomnia and pain in major depressive disorder: a sleep diary and actigraphy study, Sleep Medicine. 2010, 11: 752-758.
Yeung W.F., Chung K.F., Tso K.C., Zhang S.P., Zhang Z. and Ho L.M., Electroacupuncture for residual insomnia associated with major depressive disorder: A randomized controlled trial, Sleep. 2011, 34 (6): 807-815.


Researcher : Wei R

List of Research Outputs

Deng Y., Lam S.S.Y., Meyer U., Feldon J., Li Q., Wei R., Luk L.H.F., Chua S.E., Sham P.C., Wang Y. and McAlonan G.M., Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation, PLoS One . 2011, 6 (2): e16638.


Researcher : Wong EHM

List of Research Outputs

Wong E.H.M., Tang S.M., Garcia-Barcelo M.M., Zhang X.J., Liu J.J., Cherny S.S., Sham P.C. and Tam P.K.H., Genomi-wide association study on anorectal malformations in the Chinese population, Poster presented at the 60th Annual Meeting of the American Society of Human Genetics, Abstract 2942/T, Washington, D.C., USA, November 5, 2010. 846.


Researcher : Wong GHY

List of Research Outputs

Chan K.K.S., Hui C.L.M., Lam M.L.M., Tang Y.M., Wong G.H.Y., Chan K.W. and Chen E.Y.H., A Three-year Prospective Study of Spontaneous Eye-blink Rate in First-episode Schizophrenia: Relationship with Relapse and Neurecognitive Function, East Asian Archives of Psychiatry. 2010, 20 (4): 174-179.
Chan K.S.K., Chin Q.P., Tang Y.M., Longenecker J.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y. and Chen E.Y.H., Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals, Early Intervention in Psychiatry. 2011.
Chan K.W., Chan K.S.K., Lam M.M.L., Chiu C.P.Y., Law C.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Correlate of insight in first episode psychosis : a longitudinal perspective, Second Joint International Conference of the Hong Kong College of Psychiatrists and the Royal College of Psychiatrists (UK) (December 11-13). 2010.
Chang W.C., Tang Y.M., Hui C.L.M., Chiu C.P.Y., Lam M.M.L., Wong G.H.Y., Chung D.W.S., Law C.W., Tso S., Chan K.P.M., Hung S.F. and Chen E.Y.H., Gender differences in patients presenting with first-episode psychosis in Hong Kong: a three-year follow-up study., Australian and New Zealand Journal of Psychiatry. 2011, 45 issue 3: 199-205.
Chang W.C., Hui C.L.M., Lam M.M.L., Chan K.W., Wong G.H.Y., Tang Y.M. and Chen E.Y.H., Negative symptoms and neurocognitive deficits in first-episode schizophrenia spectrum disorder. , Schizophrenia Bulletin. 2011, Vol. 37 (suppl. 1): 240.
Chiu C.P.Y., Lam M.M.L., Chan S.K., Chung D.W., Hung S.F., Tang Y.M., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Naming Psychosis: the Hong Kong experience, Early Intervention in Psychiatry. 2010, 4 (4): 270-274.
Lam M.L.M., Chiu C.P.Y., Hui C.L.M., Law C.W., Tang Y.M., Wong G.H.Y., Chung D.W.S., Chan K.P.M., Hung S.F., Tso S.S.F. and Chen E.Y.H., The Initial Presentation on 3-Year Outcome in Patients with First Episode Psychosis in Hong Kong May M.L. Lam1*, Jennifer Y.M. Tang1, Christy L.M. Hui1, Cindy P.Y. Chiu1, Gloria H.Y. Wong1, C.W. Law2, Dicky W.S. Chung3, Kathy P.M. Chan4, Steve Tso5, S.F. Hung4 and Eric Y.H. Chen1, World Psychiatric Association Congress, Beijing, China 2010 Sept 1-5. 2010.
Lam M.L.M., Tang Y.M., Hui C.L.M., Yew C.W.S., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S.S.F., Wong G.H.Y., Yip K.C., Hung S.F. and Chen E.Y.H., Three-year outcome of Early Intervention Programme for Psychosis (EASY) in Hong Kong, Second Joint International Conference of The HK College of Psychiatrists and The Royal College of Psychiatrists (UK), Hong Kong2010 Dec 11-13 Brain, Behavior and Mind 2010 (BBM10)Advancing Psychiatric Care in the East . 2010.
Liu C.M., Chan R.C.K., Chan K.K.S., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W., Wong G.H.Y., Hui C.L.M. and Chen E.Y.H., Executive function in first-episode schizophrenia: A three-year longitudinal study of an ecologically valid test, Schizophrenia Research. 2011, 126 (1-3): 87-92.
Tang Y.M., Wong G.H.Y., Hui C.L.M., Lam M.M.L., Chiu C.P.Y., Chan K.W., Chung D.W.S., Tso S., Chan K.P.M., Yip K.C., Hung S.F. and Chen E.Y.H., Early intervention for psychosis in Hong Kong-the EASY programme, Early Intervention in Psychiatry. 2010, 4 (3): 214-219.
Wong G.H.Y., Tao H.J., Lin J., He Z., Liu H.H., Chiu C.P.Y., Chan K.W., Lam M.M.L., Hui C.L.M., Tang Y.M., Wang Y.H., Xue Z.M., Liu Z.N. and Chen E.Y.H., Default mode network anomalies in first-episode schizophrenia: Relevance to understanding delusions of reference, Second Joint International Conference of The Hong Kong College of Psychiatrists and The Royal College of Psychiatrists (UK). 2010.
Wong G.H.Y., Early symptomatology of schizophrenia, The Hong Kong Medical Diary. 2011, 16: 14-15.
Wong G.H.Y., Hui C.L.M., Tang Y.M., Chiu C.P.Y., Lam M.M.L., Chan K.W. and Chen E.Y.H., Understanding delusions of reference in schizophrenia: Psychopathological, cognitive, and neuroimaging explorations, Scientific Symposium of the Hong Kong Schizophrenia Research Society. 2010.
Xu J., Hui C.L.M., Wong G.H.Y., Tang Y.M., Lam M.M.L., Chiu C.P.Y. and Chen E.Y.H., Current situation and service for young people suffering from early psychosis in Hong Kong. , Journal of Youth Studies. 2011, 9-18.


Researcher : Wong GTH

List of Research Outputs

Wong G.T.H., Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone on cytoskeleton in dendrites and dendritic spines, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 67 P49.


Researcher : Wong HY

List of Research Outputs

Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.


Researcher : Wong JGWS

Project Title:What makes a good clinical teacher in the new medical curriculum? A focus group study on student perception
Investigator(s):Wong JGWS, Lam TP, Mak-Lieh F
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:01/2002


Project Title:A follow-up study on the severity of psychological sequelae in SARS patients
Investigator(s):Wong JGWS, Sham PC, Wong PC, McAlonan GM, Chu CM, Lee AM, Lee PWH, Tsang KWT, Chua SE
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:11/2004


List of Research Outputs

Cheung K.T., Leung A.Y.M., Chu D.W.S., Yung A.M.T., Wong J.G.W.S. and Law A.C.K., The Effectiveness of the Depression Care Management (DCM) Program on Diabetic and Hypertensive Patients, The 18th Annual Congress of Gerontology. 2010.
Siu M.W., Cheung T.Y., Chiu M.M., Kwok T.Y., Choi W.L., Lo T.K., Ting W.M., Yu P.H., Cheung C.Y., Wong J.G.W.S. and Chua S.E., The Preparedness of Hong Kong Medical Students towards Advance Directives and End-of-life Issues, East Asia Archives of Psychiatry. 2010, 20 (4): 155-162.


Researcher : Wong MMC

Project Title:Enrichment of collections in the library of the S.K. Yee Mental Health Resources and Rehabilitation Centre
Investigator(s):Wong MMC, Mak KY, Mak-Lieh F, Yau EFY
Department:Psychiatry
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2001




Researcher : Wuwongse S

List of Research Outputs

Chang R.C.C., Zhang Q., Hung H.L., Wuwongse S. and Ho Y.S., Mechanisms of cell death in Alzheimer's disease, The Eighth Asia Pacific Multidisciplinary Meeting for Nervous System Diseases, Jan. 7-8, 2011 Hong Kong. 2011, 23.
Chang R.C.C., Zhang Q., Hung H.L., Ho Y.S. and Wuwongse S., Signaling mechanism from endoplasmic reticulum collapse to induction of autophagy in neurons stressed with low molecular weight beta-amyloid peptides, The 10th International Conference on Alzheimer's & Parkinson's Disease, Barcelona, March 9-13, 2011. Abstract 350.
Chang R.C.C., Hung H.L., Wuwongse S., Zhang Q. and Ho Y.S., Stress responses of mitochondria to beta-amyloid peptide in Alzheimer's disease: do we understand the biological mechanisms now?, Croucher Advanced Study Institutes in Stress Responses of Mitochondria in Diabetes and Aging.. 2011.
Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3.
Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453.
Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17.
Hung C.H.L., Cheung Y.T., Wuwongse S., Zhang Q. and Chang R.C.C., Relationship between low molecular weight beta-amyloid peptide-induced fission/fusion imbalance and mitochondrial functions, Society for Neuroscience 2010, San Diego, USA. 2010, 247.15/H61.
Hung H.L., Cheung Y.T., Wuwongse S., Zhang Q., Ho Y.S. and Chang R.C.C., Mitochondria in Alzheimer's Disease: Relationship between morphology and functions, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P27.
Lau C.F., Ho Y.S., Poon C.H., Wuwongse S. and Chang R.C.C., Synaptic neuroprotective effect of testosterone in beta-amyloid-treated rat hippocampal neurons, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 57 P12.
Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54.
Wong G.T.H., Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone on cytoskeleton in dendrites and dendritic spines, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 67 P49.
Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Amyloid beta and corticosterone-mediated synaptic dysfunction, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 66 P46.
Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Chang R.C.C. and Law A.C.K., Neuroprotective role of antidepressants in amyloid and corticosterone-mediated synaptic dysfunction., The Croucher Foundation Conference: Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insights.. 2011, 29.
Wuwongse S., Hung H.L., Chang R.C.C. and Law A.C.K., The involvement of synaptic degeneration in major depressive disorder and antidepressant mechanisms of action., Society for Neuroscience 2010, San Diego, USA. 2010, 162.1/V9.
Wuwongse S., Chang R.C.C. and Law A.C.K., The putative neurodegenerative links between depression and Alzheimer's disease, Progress in Neurobiology. 2010, 91: 362-375.
Zhang Q., Hung H.L., Ho Y.S., Wuwongse S. and Chang R.C.C., Aggregation of the endoplasmic reticulum triggered by oligomeric Ab could facilitate formation of autophagosomes, Sixth International Symposium on Healthy Aging, March 5-6, 2011 Hong Kong. 2011, 47.


Researcher : Wuwongse S

List of Research Outputs

Chang R.C.C., Zhang Q., Hung H.L., Wuwongse S. and Ho Y.S., Mechanisms of cell death in Alzheimer's disease, The Eighth Asia Pacific Multidisciplinary Meeting for Nervous System Diseases, Jan. 7-8, 2011 Hong Kong. 2011, 23.
Chang R.C.C., Zhang Q., Hung H.L., Ho Y.S. and Wuwongse S., Signaling mechanism from endoplasmic reticulum collapse to induction of autophagy in neurons stressed with low molecular weight beta-amyloid peptides, The 10th International Conference on Alzheimer's & Parkinson's Disease, Barcelona, March 9-13, 2011. Abstract 350.
Chang R.C.C., Hung H.L., Wuwongse S., Zhang Q. and Ho Y.S., Stress responses of mitochondria to beta-amyloid peptide in Alzheimer's disease: do we understand the biological mechanisms now?, Croucher Advanced Study Institutes in Stress Responses of Mitochondria in Diabetes and Aging.. 2011.
Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress and phosphorylation of Tau protein: How can they reinforce the progression of Alzheimer's disease?, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 55 P3.
Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., Endoplasmic reticulum stress induces Tau pathology and forms vicious cycle in pathogenesis of Alzheimer's disease, The 10th International Conference on Alzheimer's & Parkinson's Diseases, Barcelona, March 9-13, 2011. Abstract 453.
Ho Y.S., Yang X., Lau C.F., Hung H.L., Wuwongse S., Zhang Q. and Chang R.C.C., The casual relationship of endoplasmic reticulum stress and phosphorylation of Tau protein may reinforce progression of neurodegeneration leading to cognitive impairment and Alzheimer's Disease, The 5th Annual Scientific Meeting of Hong Kong Society of Biological Psychiatry, March 19-20, 2011, Hong Kong. 2011, 17.
Hung C.H.L., Cheung Y.T., Wuwongse S., Zhang Q. and Chang R.C.C., Relationship between low molecular weight beta-amyloid peptide-induced fission/fusion imbalance and mitochondrial functions, Society for Neuroscience 2010, San Diego, USA. 2010, 247.15/H61.
Hung H.L., Cheung Y.T., Wuwongse S., Zhang Q., Ho Y.S. and Chang R.C.C., Mitochondria in Alzheimer's Disease: Relationship between morphology and functions, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 61 P27.
Lau C.F., Ho Y.S., Poon C.H., Wuwongse S. and Chang R.C.C., Synaptic neuroprotective effect of testosterone in beta-amyloid-treated rat hippocampal neurons, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 57 P12.
Poon C.H., Ho Y.S., Lau C.F., Wuwongse S., Chiu K., Zhang Q., Hung H.L. and Chang R.C.C., Peripheral cytokine storm disorganizes MAP2 and synaptophysin, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong. 2011, 68 P54.
Wong G.T.H., Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone on cytoskeleton in dendrites and dendritic spines, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 67 P49.
Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Law A.C.K. and Chang R.C.C., Amyloid beta and corticosterone-mediated synaptic dysfunction, Sixth International Symposium on Healthy Aging, March 5-6, 2011, Hong Kong.. 2011, 66 P46.
Wuwongse S., Hung H.L., Zhang Q., Ho Y.S., Chang R.C.C. and Law A.C.K., Neuroprotective role of antidepressants in amyloid and corticosterone-mediated synaptic dysfunction., The Croucher Foundation Conference: Alzheimer's Disease Conference: From Public Health, Basic and Clinical Science to Therapeutic Insights.. 2011, 29.
Wuwongse S., Hung H.L., Chang R.C.C. and Law A.C.K., The involvement of synaptic degeneration in major depressive disorder and antidepressant mechanisms of action., Society for Neuroscience 2010, San Diego, USA. 2010, 162.1/V9.
Wuwongse S., Chang R.C.C. and Law A.C.K., The putative neurodegenerative links between depression and Alzheimer's disease, Progress in Neurobiology. 2010, 91: 362-375.
Zhang Q., Hung H.L., Ho Y.S., Wuwongse S. and Chang R.C.C., Aggregation of the endoplasmic reticulum triggered by oligomeric Ab could facilitate formation of autophagosomes, Sixth International Symposium on Healthy Aging, March 5-6, 2011 Hong Kong. 2011, 47.


Researcher : Xu J

List of Research Outputs

Xu J., Hui C.L.M., Wong G.H.Y., Tang Y.M., Lam M.M.L., Chiu C.P.Y. and Chen E.Y.H., Current situation and service for young people suffering from early psychosis in Hong Kong. , Journal of Youth Studies. 2011, 9-18.


Researcher : Yeung WF

List of Research Outputs

Chung K.F., Kan K.K.K. and Yeung W.F., Assessing insomnia in adolescents: comparison of Insomnia Severity Index, Athens Insomnia Scale and Sleep Quality Index, Sleep Medicine. 2011, 12 (5): 463-470.
Chung K.F., Tso K.C., Yeung W.F. and Li W.H., Quality of life in major depressive disorder: the role of pain and pain catastrophizing cognition., Comprehensive Psychiatry. 2011, [Epub ahead of print].
Poon M.K., Chung K.F. and Yeung W.F., Classification of Insomnia Using Traditional Chinese Medicine (TCM) Diagnostic System: A Systematic Review, Hong Kong International Acupuncture Conference: Neurological and Mental Illness. 2011.
Yeung W.F., Chung K.F. and Poon M.K., Acupuncture and Chinese Herbal Medicine for Insomnia: A Systematic Review of Effectiveness and TCM Pattern Differentiation, Hong Kong International Acupuncture Conference: Neurological and Mental Illness. 2011.
Yeung W.F., Chung K.F., Tso K.C., Zhang S.P., Zhang Z. and Ho L.M., Electroacupuncture for residual insomnia associated with major depressive disorder: A randomized controlled trial, Sleep. 2011, 34 (6): 807-815.


Researcher : Yew CWS

List of Research Outputs

Lam M.L.M., Tang Y.M., Hui C.L.M., Yew C.W.S., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S.S.F., Wong G.H.Y., Yip K.C., Hung S.F. and Chen E.Y.H., Three-year outcome of Early Intervention Programme for Psychosis (EASY) in Hong Kong, Second Joint International Conference of The HK College of Psychiatrists and The Royal College of Psychiatrists (UK), Hong Kong2010 Dec 11-13 Brain, Behavior and Mind 2010 (BBM10)Advancing Psychiatric Care in the East . 2010.


Researcher : Ying D

List of Research Outputs

Zhang L., Yang W. and Ying D., Homozygosity mapping on a single patient - identification of homozygous regions of recent common ancestry by using population data., Human Mutation. 2011, 32(3): 345-353.


Researcher : Yip BHK

Project Title:Sequencing of the neuregulin-1 (NRG1) gene in schizophrenia patients
Investigator(s):Yip BHK, Sham PC, Cherny SS, Garcia-Barcelo MM, Tam PKH
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:08/2009
Completion Date:01/2011


List of Research Outputs

Garcia-Barcelo M.M., Miao X.P., Tang S.M., So H.C., Tang W.K., Leon T.Y.Y., So M.T., Yip B.H.K., Chen R.Y.L., Cheung E.F.C., Chen E.Y.H., Li T., Tam P.K.H., Cherny S.S. and Sham P.C., No NRG1 V266L in Chinese patients with schizophrenia, Psychiatric Genetics. 2011, 21 (1): 47-49.
Leung M.K., Cheung C., Yu K.K.K., Yip B.H.K., Sham P.C., Li Q., Chua S.E. and McAlonan G.M., Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting, Schizophrenia Bulletin. 2011, 37 (1): 199-211.
So H.C., Yip B.H.K. and Sham P.C., Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies, PLoS One. 2010, 5 (11): e13898.


Researcher : Yu GKK

List of Research Outputs

Chan I.W.P., Chu L.W., Lee P.W.H., Li S.W. and Yu G.K.K., Effects of cognitive function and depressive mood on the quality of life in Chinese Alzheimer’s disease patients in Hong Kong., Geriatr Gerontol Int.. 2011, 11(1): 69-76.
Cheung C., Yu G.K.K., Yam A., Myint V., Chua S.E. and McAlonan G.M., Intra-orbital distance as a record of social brain dysmorphology in autism, ISMRM Montreal 2011 (May 7-13, 2011). 2011.
Wong C., Yu G.K.K., Chua S.E., Cheung C. and McAlonan G.M., Do Autism Spectrum Disorders and Bipolar Disorder share a neuroanatomical phenotype?, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
Yu G.K.K., Pun E., Wong P., Chua S.E., Cheung C. and McAlonan G.M., Do Autism Spectrum Disorders and Obsessive Compulsive Disorders share a neuroanatomical phenotype?, IMFAR San Diego 2011 (May 12-14, 2011). 2011.
Yu G.K.K., Cheung C., Fung Y.Y., Fung G., McAlonan G.M. and Chua S.E., MRI brain scan study of minor physical anomalies in autism, Autism 2010 - Geneva Centre for Autism's International Symposium (November 3-5, 2010). 2010.


Researcher : Yu KKK

List of Research Outputs

Cheung C., Yu K.K.K., Fung C.M.G., Leung M.K., Wong H.Y., Li Q., Sham P.C., Chua S.E. and McAlonan G.M., Autistic Disorders and Schizophrenia: Related or Remote? An Anatomical Likelihood Estimation, PLoS One. 2010, 5 (8): e12233.
Cheung C., McAlonan G.M., Fung Y.Y., Fung C.M.G., Yu K.K.K., Tai K.S., Sham P.C. and Chua S.E., MRI Study of Minor Physical Anomaly in Childhood Autism Implicates Aberrant Neurodevelopment in Infancy, PLoS One. 2011, 6 (6): e20246.
Leung M.K., Cheung C., Yu K.K.K., Yip B.H.K., Sham P.C., Li Q., Chua S.E. and McAlonan G.M., Gray Matter in First-Episode Schizophrenia Before and After Antipsychotic Drug Treatment. Anatomical Likelihood Estimation Meta-analyses With Sample Size Weighting, Schizophrenia Bulletin. 2011, 37 (1): 199-211.
Yu K.K.K., Cheung C., Leung M.K., Li Q., Chua S.E. and McAlonan G.M., Are bipolar disorder and schizophrenia neuroanatomically distinct? An anatomical likelihood meta-analysis, Frontiers in Human Neuroscience. 2010, 26 (4): 189.
Yu K.K.K., Cheung C., Chua S.E. and McAlonan G.M., Can Asperger syndrome be distinguished from autism? An anatomic likelihood meta-analysis of MRI studies, Journal of Psychiatry and Neuroscience. 2011, 36 (2).


Researcher : Zhang SP

List of Research Outputs

Yeung W.F., Chung K.F., Tso K.C., Zhang S.P., Zhang Z. and Ho L.M., Electroacupuncture for residual insomnia associated with major depressive disorder: A randomized controlled trial, Sleep. 2011, 34 (6): 807-815.


-- End of Listing --