DEPT OF ANAESTHESIOLOGY



Researcher : Chan BKB

List of Research Outputs

Chan B.K.B., Tam L.K., Chung Y.F., Wat C.Y., Tsui S.L. and Cheung C.W., Opioids in chronic non-cancer pain, Expert Opinion on Pharmacotherapy. 2011, 12(5): 705-720.


Researcher : Chan WM

List of Research Outputs

Hung I.F.N., To K.K.W., Lee C...K..., Lee K...L..., Chan K..., Yan W...W..., Liu R..., Watt C...L..., Chan W.M., Lai K...Y..., Koo C...K..., Buckley T..., Chow F...L..., Wong K...K..., Chan H...S..., Ching C...K..., Tang B...S...F..., Lau C.Y., Li W.S., Liu S...H..., Chan K.H., Lin C...K... and Yuen K.Y., Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection , Clinical Infectious Diseases. 2011, 52(4): 447-456.
Ngai C.W., LAM M.F., Lo S.H., Cheung C.W. and Chan W.M., The use of Doppler ultrasound renal Resistive Index (RI) and Neutrophil Gelatinase-Associated Lipocalin (NGAL) in prediction of Acute Kindey Inury (AKI) in ptients with septic shock., Intermational Symposium on Intensive Care and Emergency Medicine. 22-25 Mar 2011.


Researcher : Cheung CW

Project Title:The analgesic and diuretic effects of dexmedetomidine in dental surgery under general anaesthesia
Investigator(s):Cheung CW, Ng JKF
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:08/2008
Completion Date:07/2010


Project Title:Multimodal analgesic using morphine and COX-2 with or without dexmedetomidine for laparoscopic colorectal surgery
Investigator(s):Cheung CW, Ng JKF
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:08/2009


Project Title:13th World Congress on Pain Analgesic Effect of Intranasal Dexmedetomidine in Third Molar Surgery under Local Anaesthesia
Investigator(s):Cheung CW
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:08/2010
Completion Date:09/2010


Project Title:Adjuvant Tramadol/Acetaminophen Combination for Down Stepping Patient-Controlled Morphine Consumption and Related Side Effects after Lower Abdominal Surgery
Investigator(s):Cheung CW
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:10/2010


List of Research Outputs

Chan A...K...M..., Cheung C.W. and Chong Y...K..., Alpha-2 agonists in acute pain management, Expert Opinion on Pharmacotherapy. 2010, 11(17): 2849-2868.
Chan B.K.B., Tam L.K., Chung Y.F., Wat C.Y., Tsui S.L. and Cheung C.W., Opioids in chronic non-cancer pain, Expert Opinion on Pharmacotherapy. 2011, 12(5): 705-720.
Cheung C.W., Choi W.W.S., Leung M.Y.Y., Lui F., Ng J.K.F., Ho A.M.H. and Irwin M.G., A double blind randomized crossover study to evaluate the timing of pregabalin for third molar surgery under local anesthesia, Jounral of Oral and Maxillofacial Surgery.. 2011, 70(1): 25-30.
Cheung C.W., Ng J.K.F., Liu J., Yuen V.M.Y., Ho M.H.A. and Irwin M.G., Analgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia, British Journal of Anaestheisa.. 2011, 107(3): 430-437.
Cheung C.W., Chairman, , Abbott International Anaesthesia Summit, Sheraton HK HOtel & Towers, 13 May. 2011.
Cheung C.W., Chairman, First Plenary Session., Annual Scientifc Anaesthesiology, 20-21 November, Hong Kong.. 2010.
Cheung C.W., Chairman, Free paper presentation , Annual Scientific in Anaesthesiology, 20-21 November, Hong Kong.. 2010.
Cheung C.W., Chairman, Plenary Session 3,, Combined Scientific Meeting (Australia & New Zealand College of Anaesthetists and Hong Kong College of Anaesthesiologist) 16 May.. 2011.
Cheung C.W., Chairman, Practical aspects of arrhythmia Management (Topic: Advances in heat Failure Management), CardioRhythm, 27 February, Hong Kong.. 2011.
Cheung C.W., Liman S. and Ng J.K.F., Effect of ketamine on chronic post-ischemia pain (CPIP) model in Sprague-Dawley rats., Combined Scientific Meeting (Australia & New Zealand College of Anaesthetists and Hong Kong College of Anaesthesiologists) 14-17 May 2011.
Cheung C.W., Ng J.K.F., Choi W.W.S., Chiu W.K., Ying C.L.A. and Irwin M.G., Evaluation of the analgesic efficacy of local dexmedetomidine application, Clinical Journal of Pain. 2011, 27(5): 377-382.
Cheung C.W., Peer Reviewer, Case Reports in Medicine. 2011.
Cheung C.W., Peer Reviewer, Pain Research and Treatment. 2011.
Cheung C.W., Peer Reviewer, The Tohoku Journal of Experimental Medicine. 2011.
Cheung C.W., Speaker, Acute Pain Management inWound Dr3ssing/Minor Surgery, Multi-specialty Medical Mega Conference (M3C), Langham Place Hotel, Hong Kong. 16 April.. 2011.
Cheung C.W., Speaker, Sedation in Dental Surgery, Certificate Course on Dental Nursing in Oral Surgery, The Federation of Medical Societies of Hong Kong, 18 March.. 2011.
Cheung C.W., Speaker, Updated on Acute Pain Management, The 3rd Scientific Symposium of Hospital Medicine, Annual Scientific Meeting of Macau Physician Association of Public Hospital. L'arc Hotel, Macau. 17 April.. 2011.
Cheung C.W., Speaker, Use of alpha-2 agonist in acute postoperativ pain management, Shanghai Satellite Meeting - East meets West, 19-20 May, Kerry Hotel, Pudng, Shanghai.. 2011.
Ho A...M...H..., Dion P...W..., Yeung Y...H...H..., Ng C...S...H..., Karmakar M...K..., Crtichley L...A...H..., Rainer T...R..., Cheung C.W. and Tay B...A..., Resuscitation, Fresh-frozen plasma transfusion strategy in trauma with massive and ongoing bleeding. Common (sense) and sensibility. 2010, 81(9): 1079-81.
Ho A.M.H., Dion P.W., Ng C.S.H., Cheung C.W., Yeung J.H.H. and Critchley L.A.H., 1:1. Letter to Editor, Resuscitation. 2011, May 82 (5): 627-628.
Ho A.M.H., Ricci C.J., Ng C.S.H., Critchley L.A.H., Ho A.K., Karmakar M.K., Ng S.K. and Cheung C.W., The Medial-transverse approach for internal jugular vein cannulation - an example of lateral thinking, The Journal of Emergency Medicine. In press.. 2011.
Huang S.M., Cheung C.W., Chang C.S., Tang C.H., Liu J.F., Lin Y.H., Chen J.H., Ko S.H., Wong K. and Lu D.Y., Phloroglucional derivative MCPP induces cell apoptosis in human colon cancer, Journal of Cellular Biochemistry. 2011, 112(2): 643-652.
Lu D...Y..., Leung Y...M..., Cheung C.W., Chen Y...R... and Wong K., Glial cell line-derived neurotrophic factor induces cell migration and matrix metalloproteinase-13 expression in glioma cells, Biochemical Pharmacology. 2010, 80(8): 1201-1209.
Ng J.K.F., Cheung C.W. and Lee Y., Low dose desmopressin improves hypothermia induced impairmnt of primary haemostasis in healthy volunteers, Anaesthesia. 2011, 66(11): 999-1005.
Ngai C.W., LAM M.F., Lo S.H., Cheung C.W. and Chan W.M., The use of Doppler ultrasound renal Resistive Index (RI) and Neutrophil Gelatinase-Associated Lipocalin (NGAL) in prediction of Acute Kindey Inury (AKI) in ptients with septic shock., Intermational Symposium on Intensive Care and Emergency Medicine. 22-25 Mar 2011.
Tsui S.L. and Cheung C.W., Cancer Pain, In: SL Tsui, PP Chen, JKF Ng, Pain Medicine: A Multidisciplinary Approach. 2010.
Wong K., Cheung C.W., So E., Leung Y.M. and Cheng T.H., Propofol attenuates apoptosis induced by angiotensin II via the PI3-kinase/Akt pathway in neonatal rat cardiomyocytes, Euroanaesthesia, 2011, Amsterdam, the Netherlands 11-14 June 2011.
Wong K.L., Leung Y.M., Lu D.Y., Cheung C.W. and Cheng T.H., The antioxidative effect of propofol on angiotensin II-induced apoptosis in neonatal rat cardiomyocytes, The International Academy of Cardiology, 15th World Congress on Heart Disease, Annual Scientific Sessions 2010, Vancouver, Canada. 2010.
Yang L...Q..., Tao K...M..., Cheung C.W., Liu Y...T..., Tao Y..., Wu F...X... and Yu W...F..., The effect of isoflurane or propofol anaesthesia on liver injury after partial hepatectomy in cirrhotic patients, Anaesthesia. 2010, 65(11): 1094-1100.
Yang L.Q., Tao K.M., Liu Y.T., Cheung C.W., Wong G.T.C., Lv H., Song J.G., Wu F.X. and Yu W.F., Remifentanil preconditioning reduces hepatic-ischemia reperfusion injury in rats via inducible nitric oxide synthase expression, Anesthesiology. 2011, May 114(5): 1036-1047.


Researcher : Chiang JCS

List of Research Outputs

Chiang J.C.S., Irwin M.G., Hussain A., Tang Y.K. and Hiong Y.T., Anaesthesia for emergency caesarean section in a patient with large anterior mediastinal tumour presenting as intrathoracic airway compression and superior vena cava obstruction, Case Reports in Medicine. 2010, 2010: 708481.


Researcher : Chou CW

List of Research Outputs

Chou C.W., Wong G.T.C., Lim G., McCabe M.F., Wang S., Irwin M.G. and Mao J., Peripheral nerve injury alters the expression of NF-κB in the rat's hippocampus , Brain Research. 2011, 1378: 66-71.


Researcher : Chung YF

List of Research Outputs

Chan B.K.B., Tam L.K., Chung Y.F., Wat C.Y., Tsui S.L. and Cheung C.W., Opioids in chronic non-cancer pain, Expert Opinion on Pharmacotherapy. 2011, 12(5): 705-720.


Researcher : Gao X

List of Research Outputs

Gao X., Xu Y., Lei S., Liu Y. and Xia Z., Synergy Of N-Acetylcysteine And Allopurinol Improves Systemic Oxygen Delivery In Rats With Streptozotocin-Induced Diabetes, The FASEB Journal. 2011, 25: 805.2.
Xu Y., Gao X., Xu B., Liu H., Irwin M.G. and Xia Z., Allopurinol Attenuates Left Ventricular Dysfunction In The Early Stage of Streptozotocin-Induced Diabetes In Rats, The FASEB Journal. 2011, 25: Ib374.


Researcher : Greenland KB

List of Research Outputs

Greenland K.B., Edwards M.J., Hutton N.J., Challis V.J., Irwin M.G. and Sleigh J.W., Changes in airway configuration with different head and neck positions using magnetic resonance imaging of normal airways: a new concept with possible clinical applications, Br J Anaesth. 2010, 105(5): 683-690.


Researcher : Hiong YT

List of Research Outputs

Chiang J.C.S., Irwin M.G., Hussain A., Tang Y.K. and Hiong Y.T., Anaesthesia for emergency caesarean section in a patient with large anterior mediastinal tumour presenting as intrathoracic airway compression and superior vena cava obstruction, Case Reports in Medicine. 2010, 2010: 708481.


Researcher : Huang Z

List of Research Outputs

Xia Z., Huang Z., Liu J., Wong G.T.C. and Irwin M.G., Fructose-1,6-Bisphosphate Reduces Myocardial Injury in Patients Undergoing Heart Valve Surgery, Anesthesiology. 2010, 113: A1541.


Researcher : Hui TWC

List of Research Outputs

Yuen V.M.Y., Hui T.W.C., Irwin M.G., Yao T.J., Wong G.L.S. and Yuen M.K., Optimal timing for the administration of intranasal dexmedetomidine for premedication in children, Anaesthesia. 2010.


Researcher : Hussain A

List of Research Outputs

Chiang J.C.S., Irwin M.G., Hussain A., Tang Y.K. and Hiong Y.T., Anaesthesia for emergency caesarean section in a patient with large anterior mediastinal tumour presenting as intrathoracic airway compression and superior vena cava obstruction, Case Reports in Medicine. 2010, 2010: 708481.


Researcher : Irwin MG

Project Title:A comparative study of hydroxyethyl starch (130/0.4) and gelatin on the immune response in paediatric scoliosis surgery
Investigator(s):Irwin MG, Wylie SJ
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:01/2009


Project Title:NADPH Oxidase Over Expression in the Myocardium of Diabetic Rats Compromises Opioid Agonist Induced Cardioprotection
Investigator(s):Irwin MG, Vanhoutte PMGR, Xia Z
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2009


Project Title:A Comparison of Two doses of Intranasal Dexmedetomidine for Premedication in Children – a double-blind randomized controlled trial
Investigator(s):Irwin MG, Yuen VMY, Wong GLS, Yao T, Hui TWC
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:12/2009
Completion Date:11/2010


Project Title:Radiofrequency therapy for chronic and cancer pain patient
Investigator(s):Irwin MG, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Role of STAT-3 in non-invasive remote ischemic preconditioning mediated cardioprotection in Type 1 diabetic rodents
Investigator(s):Irwin MG, Vanhoutte PMGR, Wong GTC, Xia Z
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2011


Project Title:14th EuroSIVA Annual Scientific Meeting Remifentanil preconditioning activates STAT3 and attenuates postischaemic myocardial infarction and left ventricular dysfunction in rats
Investigator(s):Irwin MG
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:06/2011
Completion Date:06/2011


List of Research Outputs

Cheung C.W., Choi W.W.S., Leung M.Y.Y., Lui F., Ng J.K.F., Ho A.M.H. and Irwin M.G., A double blind randomized crossover study to evaluate the timing of pregabalin for third molar surgery under local anesthesia, Jounral of Oral and Maxillofacial Surgery.. 2011, 70(1): 25-30.
Cheung C.W., Ng J.K.F., Liu J., Yuen V.M.Y., Ho M.H.A. and Irwin M.G., Analgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia, British Journal of Anaestheisa.. 2011, 107(3): 430-437.
Cheung C.W., Ng J.K.F., Choi W.W.S., Chiu W.K., Ying C.L.A. and Irwin M.G., Evaluation of the analgesic efficacy of local dexmedetomidine application, Clinical Journal of Pain. 2011, 27(5): 377-382.
Chiang J.C.S., Irwin M.G., Hussain A., Tang Y.K. and Hiong Y.T., Anaesthesia for emergency caesarean section in a patient with large anterior mediastinal tumour presenting as intrathoracic airway compression and superior vena cava obstruction, Case Reports in Medicine. 2010, 2010: 708481.
Chou C.W., Wong G.T.C., Lim G., McCabe M.F., Wang S., Irwin M.G. and Mao J., Peripheral nerve injury alters the expression of NF-κB in the rat's hippocampus , Brain Research. 2011, 1378: 66-71.
Fan Q., Yang X.C., Liu Y., Wang L.F., Liu S.H., Ge Y.G., Chen M.L., Wang W., Zhang L.K., Irwin M.G. and Xia Z., Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans, Clinical Science (Lond). 2010, 120(6): 251-261.
Greenland K.B., Edwards M.J., Hutton N.J., Challis V.J., Irwin M.G. and Sleigh J.W., Changes in airway configuration with different head and neck positions using magnetic resonance imaging of normal airways: a new concept with possible clinical applications, Br J Anaesth. 2010, 105(5): 683-690.
Irwin M.G., 1st Asia Pacific Research Ethics Conference , NHG Research and Development Office and the Domain Specific Review Board, Singapore. 2010.
Irwin M.G., Advisory Board member, Medical Grapevine . 2010.
Irwin M.G., Board Member, International Society of Anesthetic Pharmacology. 2010.
Irwin M.G., Board member, Children's Surgical Centre, Cambodia. 2010.
Irwin M.G., Board of Directors meeting, International Society for Anaesthetic Pharmacology, San Diego, California. 2010.
Irwin M.G., Clinical Ivestigator incentives for participation in industry-sponsored clinical trials, Clinical Trial Magnifer Conference, Kota Kinabalu, Malaysia. 2010.
Irwin M.G., Committee member, Health Services Research Committee. 2010.
Irwin M.G., Editor Board member, Anaesthesia and Intensive Care Medicine. 2010.
Irwin M.G., Editorial Board Member, Acta Anaesthesia Taiwanica. 2010.
Irwin M.G., Editorial Board Member, Anaesthesia. 2010.
Irwin M.G., Editorial Board Member, Case Reports in Medicine. 2010.
Irwin M.G., Editorial Board Member, Expert Opinion on Pharmacotherapy. 2010.
Irwin M.G., Editorial Board Member, Pain Research and Treatment. 2010.
Irwin M.G., Editorial Board member, World Journal of Gastrointestial Surgery. 2010.
Irwin M.G., Forum on Advanced in Clinical Anaesthesia, The Second Affiliated Hospital, Anhui, China. 2010.
Irwin M.G., Harmony Amidst Diversity, 17th ASEAN Congress of Anesthesiologists, Manila, Philippine. 2011.
Irwin M.G., Intravenous anaesthesia and perioperative cardioprotection, South American Society for Intravenous Anaesthesia. 2011.
Irwin M.G., Journal of Pharmaceutical & Biomedical Analysis, 2011.
Irwin M.G., Member, HK Hospital Authority Expert Panel in Anaesthesiology. 2010.
Irwin M.G. and Wong G.T.C., Neurobiology and Mechanisms of Pain, In: Siu Lun TSUI, Phoon Ping CHEN and Kwok Fu Jacobus NG, Pain Medicine A Multidisplinary Approach. Hong Kong, 2010, 1 - 8.
Irwin M.G., Organ Protection, European Society for Intravenous Anaesthesia, Crans Montana, Switzerland. 2011.
Irwin M.G., Panel member, Faculty 1000 Medicine (Cardiovascular drugs in anaesthesia). 2011.
Irwin M.G., Peer Reviewer, Anaesthesia and Intensive Care. 2011.
Irwin M.G., Peer Reviewer, Anesthesia and Analgesia. 2011.
Irwin M.G., Peer Reviewer, Asean Journal of Anaesthesiology. 2011.
Irwin M.G., Peer Reviewer, Asian Journal of Maxillofacial Surgery. 2011.
Irwin M.G., Peer Reviewer, British Journal of Anaethesia. 2011.
Irwin M.G., Peer Reviewer, Canadian Journal of Anaesthesia. 2011.
Irwin M.G., Peer Reviewer, Canadian Journal of Physiology & Pharmacology. 2011.
Irwin M.G., Peer Reviewer, Exper Opinion on Pharmacotherapy . 2011.
Irwin M.G., Peer Reviewer, Hong Kong Medical Journal. 2011.
Irwin M.G., Peer Reviewer, Jounral of Clinical Anaesthesia. 2011.
Irwin M.G., Peer Reviewer, Journal of Paediatrics. 2011.
Irwin M.G., Peer Reviewer, Medical Science Monitor. 2011.
Irwin M.G., Peer Reviewer, Obstetrics and Gynaecology. 2011.
Irwin M.G., Peer Reviewer, Surgical Practice. 2011.
Irwin M.G., Peer reviewer, Anaesthesia. 2011.
Irwin M.G., Peer reviewer, Anesthesiology. 2011.
Irwin M.G., Referee Register, Hong Kong Research Grants. 2011.
Irwin M.G., Referee, Health Services Reearch Committee/Health Care & Promotion Fund Committee. 2011.
Irwin M.G., Reviewer, Archives of Medical Research. 2010.
Irwin M.G., Reviewer, Clinical Biochemistry. 2010.
Irwin M.G., Senior Editor, Hong Kong Medical Journal. 2010.
Irwin M.G., The future of intravenous anesthetic, Chinese Medical Association, Beijing.. 2010.
Irwin M.G., The magic of opioids, Health Care Intrnational, Glasgow, UK. 2011.
Irwin M.G., the 3rd Wold Congress of Total Intravenous Anaesthesia and Target Controlled Infusion, The World Society of Intravenous naesthesia, Singapore. 2011.
Jiang L., Wong G.T.C., Lu Y., Xia Z. and Irwin M.G., Remote pharmacological post-conditioning by intrathecal morphine: cardiac protection from spinal opioid receptor activation, Acta Anaesthesiologica Scandinavica . 2010, 54(9): 1097-1104.
Lei S., Liu Y., Liu H., Xia Z.Y., Irwin M.G. and Xia Z., N-acetylcysteine inhibits NADPH oxidase activation and attenuates lipid peroxidation in the heart, lung, liver and kidney in streptozotocin-induced diabetic rats, The FASEB Journal. 2011, 25: 805.1.
Liang S. and Irwin M.G., Review of anesthesia for middle ear surgery, Anesthesiology Clinics. 2010, 28(3): 519-528.
Mao X., Ng J.K.F., Irwin M.G., Vanhoutte P.M.G.R. and Xia Z., N-Acetylcysteine Enhances Cardiac HO-1 Protein Expression and Antioxidant Capacity in Diabetic Rats, Anesthesiology. 2010, 112: in press.
Mei B., Wong G.T.C., Xia Z. and Irwin M.G., The cardioprotective effect of remifentanil is reduced following high dose exposure, TIVA-TCI 2011 3rd World Congress of Total Intravenous Anaesthesia and target Controlled infusion, Singapore. 2011.
Qiao S., Liu Y., Wang T., Mao X., Wong G.T.C., Xia Z. and Irwin M.G., Remifentanil preconditioning confers cardioprotection via the JAK/STAT but not PI3K/Akt pathway in rats, The FASEB Journal. 2011, 25: 1085.6.
Tan G. and Irwin M.G., Recent advances in using propofol by non-anesthesiologists, F1000 Med Rep. 2010, 2: 79.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., Effects of N-acetylcysteine and allopurinol on myocardial adiponectin content and adiponectin receptor expression in rats with streptozotocininduced diabetes, The FASEB Journal. 2011, 25: 805.4.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats, Anesth Analg. 2011, 112: S-01-S-418.
Wang Y., Wong G.T.C., Man K. and Irwin M.G., The Effect of Intravenous and Intrathecal Morphine Preconditioning on Hepatic Ischemia-reperfusion Injury in Normal and Cirrhotic Livers, 15th Research Postgraduate Symposium, Faculty of Medicine, University of Hong Kong. 2010.
Wong G.T.C., Huang Z., Ji S. and Irwin M.G., Remifentanil reduces the release of biochemical markers of myocardial damage after coronary artery bypass surgery: a randomized trial, J Cardiothorac Vasc Anesth. 2010, 24(5): 790-796.
Xia Z., Irwin M.G., Wong G.T.C., Ng J.K.F., Wang T. and Lei S., "The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats". International Anesthesia Research Society (IARS) 2011 annual meeting. Best of Category Abstract Award, International Anesthesia Research Society (IARS). 2011, 112: S-01-S-418.
Xia Z., Qiao S., Liu Y., Wang T., Mao X.W., Liu H., Wong G.T.C. and Irwin M.G., Antioxidant N-Acetylcysteine Restores Remifentanil Preconditioning Cardioprotection In Rats With Streptozotocin-Induced Diabetes, Anesth Analg. 2011, 112: S-01-S-418.
Xia Z., Huang Z., Liu J., Wong G.T.C. and Irwin M.G., Fructose-1,6-Bisphosphate Reduces Myocardial Injury in Patients Undergoing Heart Valve Surgery, Anesthesiology. 2010, 113: A1541.
Xu J., Xia Z.Y., Irwin M.G., Wong G.T.C. and Xia Z., Propofol Enhances HO-1 Expression and Ameliorates Hyperglycemia Induced Cardiomyocyte Hypertrophy, Anesthesiology. 2010, 113: A1409.
Xu Y., Gao X., Xu B., Liu H., Irwin M.G. and Xia Z., Allopurinol Attenuates Left Ventricular Dysfunction In The Early Stage of Streptozotocin-Induced Diabetes In Rats, The FASEB Journal. 2011, 25: Ib374.
Yang L.Q., Song J.C., Irwin M.G., Song J.G., Sun Y.M. and Yu W.F., A clinical prospective comparison of anesthetics sensitivity and hemodynamic effect among patients with or without obstructive jaundice, Acta Anaesthesiol Scand. 2010, 54(7): 871-877.
Yuen V.M.Y., Hui T.W.C., Irwin M.G., Yao T.J., Wong G.L.S. and Yuen M.K., Optimal timing for the administration of intranasal dexmedetomidine for premedication in children, Anaesthesia. 2010.


Researcher : Jiang L

List of Research Outputs

Jiang L., Wong G.T.C., Lu Y., Xia Z. and Irwin M.G., Remote pharmacological post-conditioning by intrathecal morphine: cardiac protection from spinal opioid receptor activation, Acta Anaesthesiologica Scandinavica . 2010, 54(9): 1097-1104.


Researcher : Lee Y

List of Research Outputs

Ng J.K.F., Cheung C.W. and Lee Y., Low dose desmopressin improves hypothermia induced impairmnt of primary haemostasis in healthy volunteers, Anaesthesia. 2011, 66(11): 999-1005.


Researcher : Lei S

List of Research Outputs

Gao X., Xu Y., Lei S., Liu Y. and Xia Z., Synergy Of N-Acetylcysteine And Allopurinol Improves Systemic Oxygen Delivery In Rats With Streptozotocin-Induced Diabetes, The FASEB Journal. 2011, 25: 805.2.
Lei S., Liu Y., Liu H., Xia Z.Y., Irwin M.G. and Xia Z., N-acetylcysteine inhibits NADPH oxidase activation and attenuates lipid peroxidation in the heart, lung, liver and kidney in streptozotocin-induced diabetic rats, The FASEB Journal. 2011, 25: 805.1.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., Effects of N-acetylcysteine and allopurinol on myocardial adiponectin content and adiponectin receptor expression in rats with streptozotocininduced diabetes, The FASEB Journal. 2011, 25: 805.4.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats, Anesth Analg. 2011, 112: S-01-S-418.
Xia Z., Irwin M.G., Wong G.T.C., Ng J.K.F., Wang T. and Lei S., "The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats". International Anesthesia Research Society (IARS) 2011 annual meeting. Best of Category Abstract Award, International Anesthesia Research Society (IARS). 2011, 112: S-01-S-418.


Researcher : Liman S

List of Research Outputs

Cheung C.W., Liman S. and Ng J.K.F., Effect of ketamine on chronic post-ischemia pain (CPIP) model in Sprague-Dawley rats., Combined Scientific Meeting (Australia & New Zealand College of Anaesthetists and Hong Kong College of Anaesthesiologists) 14-17 May 2011.


Researcher : Liu H

List of Research Outputs

Lei S., Liu Y., Liu H., Xia Z.Y., Irwin M.G. and Xia Z., N-acetylcysteine inhibits NADPH oxidase activation and attenuates lipid peroxidation in the heart, lung, liver and kidney in streptozotocin-induced diabetic rats, The FASEB Journal. 2011, 25: 805.1.
Xia Z., Qiao S., Liu Y., Wang T., Mao X.W., Liu H., Wong G.T.C. and Irwin M.G., Antioxidant N-Acetylcysteine Restores Remifentanil Preconditioning Cardioprotection In Rats With Streptozotocin-Induced Diabetes, Anesth Analg. 2011, 112: S-01-S-418.
Xu Y., Gao X., Xu B., Liu H., Irwin M.G. and Xia Z., Allopurinol Attenuates Left Ventricular Dysfunction In The Early Stage of Streptozotocin-Induced Diabetes In Rats, The FASEB Journal. 2011, 25: Ib374.


Researcher : Liu J

List of Research Outputs

Cheung C.W., Ng J.K.F., Liu J., Yuen V.M.Y., Ho M.H.A. and Irwin M.G., Analgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia, British Journal of Anaestheisa.. 2011, 107(3): 430-437.


Researcher : Lu Y

List of Research Outputs

Jiang L., Wong G.T.C., Lu Y., Xia Z. and Irwin M.G., Remote pharmacological post-conditioning by intrathecal morphine: cardiac protection from spinal opioid receptor activation, Acta Anaesthesiologica Scandinavica . 2010, 54(9): 1097-1104.


Researcher : Lui F

List of Research Outputs

Cheung C.W., Choi W.W.S., Leung M.Y.Y., Lui F., Ng J.K.F., Ho A.M.H. and Irwin M.G., A double blind randomized crossover study to evaluate the timing of pregabalin for third molar surgery under local anesthesia, Jounral of Oral and Maxillofacial Surgery.. 2011, 70(1): 25-30.
Lui F. and Ng J.K.F., Adjuvant analgesics in acute pain, Expert Opinion on Pharmacotherapy. 2011, 12(3): 363-85.


Researcher : Mao X

List of Research Outputs

Mao X., Ng J.K.F., Irwin M.G., Vanhoutte P.M.G.R. and Xia Z., N-Acetylcysteine Enhances Cardiac HO-1 Protein Expression and Antioxidant Capacity in Diabetic Rats, Anesthesiology. 2010, 112: in press.


Researcher : Mei B

List of Research Outputs

Mei B., Wong G.T.C., Xia Z. and Irwin M.G., The cardioprotective effect of remifentanil is reduced following high dose exposure, TIVA-TCI 2011 3rd World Congress of Total Intravenous Anaesthesia and target Controlled infusion, Singapore. 2011.
Zhang Y., Lu Y., Mei B., Zhou Y.M., Chen Z.W. and Wong T.M., Intracerebroventricular administration of morphone confers remote cardioprotecion - role of opioid receptors and calmodulin, European J Pharmacology. 2011, 656(1-3): 74-80.


Researcher : Ng JKF

Project Title:Effect of non-steroidal anti-inflammatory agents on platelet function and blood loss in patients undergoing major joint replacement surgery
Investigator(s):Ng JKF, Chiu PKY, Tang WM
Department:Anaesthesiology
Source(s) of Funding:Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme
Start Date:10/2007


Project Title:Effect of desmopressin on platelet dysfunction associated with mild hypothermia in healthy volunteers
Investigator(s):Ng JKF, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:12/2009
Completion Date:11/2011


Project Title:Vascular effects of dexmedetomidine
Investigator(s):Ng JKF, Leung GPH, Vanhoutte PMGR
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


List of Research Outputs

Cheung C.W., Choi W.W.S., Leung M.Y.Y., Lui F., Ng J.K.F., Ho A.M.H. and Irwin M.G., A double blind randomized crossover study to evaluate the timing of pregabalin for third molar surgery under local anesthesia, Jounral of Oral and Maxillofacial Surgery.. 2011, 70(1): 25-30.
Cheung C.W., Ng J.K.F., Liu J., Yuen V.M.Y., Ho M.H.A. and Irwin M.G., Analgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia, British Journal of Anaestheisa.. 2011, 107(3): 430-437.
Cheung C.W., Liman S. and Ng J.K.F., Effect of ketamine on chronic post-ischemia pain (CPIP) model in Sprague-Dawley rats., Combined Scientific Meeting (Australia & New Zealand College of Anaesthetists and Hong Kong College of Anaesthesiologists) 14-17 May 2011.
Cheung C.W., Ng J.K.F., Choi W.W.S., Chiu W.K., Ying C.L.A. and Irwin M.G., Evaluation of the analgesic efficacy of local dexmedetomidine application, Clinical Journal of Pain. 2011, 27(5): 377-382.
Ho P.T., Li C.F., Ng Y.K., Tsui S.L. and Ng J.K.F., Prevalence of and factors associated with psychiatric morbidity in chronic pain patients, Journal of Psychosomatic Research. 2011, 70(6): 541-7.
Lui F. and Ng J.K.F., Adjuvant analgesics in acute pain, Expert Opinion on Pharmacotherapy. 2011, 12(3): 363-85.
Mao X., Ng J.K.F., Irwin M.G., Vanhoutte P.M.G.R. and Xia Z., N-Acetylcysteine Enhances Cardiac HO-1 Protein Expression and Antioxidant Capacity in Diabetic Rats, Anesthesiology. 2010, 112: in press.
Ng F.Y., Ng J.K.F., Chiu P.K.Y., Yan C.H., Chan C.W. and Yeung S.S., Postoperative Pain Control After Total Knee Arthroplasty: A Comparison Of Continuous Femoral Nerve Block And Periarticular Soft Tissue Injection, Hong Kong Orthopaedic Association Annual Congress. 2010, 15.
Ng J.K.F., ISRN Anesthesiology, 2011.
Ng J.K.F., Cheung C.W. and Lee Y., Low dose desmopressin improves hypothermia induced impairmnt of primary haemostasis in healthy volunteers, Anaesthesia. 2011, 66(11): 999-1005.
Ng J.K.F., Neuropathic Pain, In: Tsui SL, Chen PP, Ng KFJ, Pain Medicine: A Multidisciplinary Approach. HKU Press, 2010.
Ng J.K.F., In: Tsui SL, Chen PP, Ng KFJ, Pain Medicine: A Multidisciplinary Approach. 2010.
Ng J.K.F., Platelet And Global Haemostatic Effects Of Common Traditional Chinese Herbal Medicines: Implications For Anaesthesia, Australian And New Zealand College Of Anaesthetists & Hong Kong College Of Anaesthesiologists. 2011.
Ng J.K.F., Sticky Content: Update On Antiplatelet And Anticoagulant Drugs, Australian And New Zealand College Of Anaesthetists & Hong Kong College Of Anaesthesiologists. 2011.
Ng J.K.F., The Use Of Dexmedetomidine And Remifentanil In Difficult Airway Management, International Difficult Airway Conference. 2010.
Ng J.K.F., are your patient's platelets working properly?, Hong Kong Sanatorium & Hospital. 2010.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., Effects of N-acetylcysteine and allopurinol on myocardial adiponectin content and adiponectin receptor expression in rats with streptozotocininduced diabetes, The FASEB Journal. 2011, 25: 805.4.
Wong S.W.E., Man R.Y.K., Vanhoutte P.M.G.R. and Ng J.K.F., L-arginine and Arginase Products Increase Contractions to Dexmedetomidine in the Rat Aorta with Endothelium, 15th Research Postgraduate Symposium, Hong Kong, December 1-2, 2010. 187.
Xia Z., Irwin M.G., Wong G.T.C., Ng J.K.F., Wang T. and Lei S., "The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats". International Anesthesia Research Society (IARS) 2011 annual meeting. Best of Category Abstract Award, International Anesthesia Research Society (IARS). 2011, 112: S-01-S-418.


Researcher : Qiao S

List of Research Outputs

Qiao S., Liu Y., Wang T., Mao X., Wong G.T.C., Xia Z. and Irwin M.G., Remifentanil preconditioning confers cardioprotection via the JAK/STAT but not PI3K/Akt pathway in rats, The FASEB Journal. 2011, 25: 1085.6.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., Effects of N-acetylcysteine and allopurinol on myocardial adiponectin content and adiponectin receptor expression in rats with streptozotocininduced diabetes, The FASEB Journal. 2011, 25: 805.4.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats, Anesth Analg. 2011, 112: S-01-S-418.
Xia Z., Qiao S., Liu Y., Wang T., Mao X.W., Liu H., Wong G.T.C. and Irwin M.G., Antioxidant N-Acetylcysteine Restores Remifentanil Preconditioning Cardioprotection In Rats With Streptozotocin-Induced Diabetes, Anesth Analg. 2011, 112: S-01-S-418.


Researcher : Rodrigo MRC

Project Title:4th South Asian Confederation of Anaesthesiologists Congress Anaesthesia for Orthognathic Surgery
Investigator(s):Rodrigo MRC
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:09/1999


Project Title:The Association of Dental Anaesthetists 25th Anniversary Summer Scientific Meeting Patient Controlled Sedation with Propolfol
Investigator(s):Rodrigo MRC
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:06/2002




Researcher : Sun NCH

List of Research Outputs

Siu D.C.W., Sun N.C.H., Lau T.W., Yiu K.H., Leung F.K.L. and Tse H.F., Siu CW, Sun NC, Lau TW, Yiu KH, Leung F, Tse HF: Preoperative cardiac risk assessment in geriatric patients with hip fractures: an orthopedic surgeons' perspective. , Osteoporos Int. 2010 Dec;21(Suppl 4):S529-34. Epub 2010 Nov 6. 2010.
Wong G.T.C. and Sun N.C.H., Providing perioperative care for patients with hip fractures, Osteoporosis International. 2010, 21(Suppl 4): 547-553.


Researcher : Tam LK

List of Research Outputs

Chan B.K.B., Tam L.K., Chung Y.F., Wat C.Y., Tsui S.L. and Cheung C.W., Opioids in chronic non-cancer pain, Expert Opinion on Pharmacotherapy. 2011, 12(5): 705-720.


Researcher : Tan G

List of Research Outputs

Tan G. and Irwin M.G., Recent advances in using propofol by non-anesthesiologists, F1000 Med Rep. 2010, 2: 79.


Researcher : Tang YK

List of Research Outputs

Chiang J.C.S., Irwin M.G., Hussain A., Tang Y.K. and Hiong Y.T., Anaesthesia for emergency caesarean section in a patient with large anterior mediastinal tumour presenting as intrathoracic airway compression and superior vena cava obstruction, Case Reports in Medicine. 2010, 2010: 708481.


Researcher : Tsui SL

List of Research Outputs

Chan B.K.B., Tam L.K., Chung Y.F., Wat C.Y., Tsui S.L. and Cheung C.W., Opioids in chronic non-cancer pain, Expert Opinion on Pharmacotherapy. 2011, 12(5): 705-720.
Ho P.T., Li C.F., Ng Y.K., Tsui S.L. and Ng J.K.F., Prevalence of and factors associated with psychiatric morbidity in chronic pain patients, Journal of Psychosomatic Research. 2011, 70(6): 541-7.
Tsui S.L. and Cheung C.W., Cancer Pain, In: SL Tsui, PP Chen, JKF Ng, Pain Medicine: A Multidisciplinary Approach. 2010.


Researcher : Wang T

List of Research Outputs

Qiao S., Liu Y., Wang T., Mao X., Wong G.T.C., Xia Z. and Irwin M.G., Remifentanil preconditioning confers cardioprotection via the JAK/STAT but not PI3K/Akt pathway in rats, The FASEB Journal. 2011, 25: 1085.6.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., Effects of N-acetylcysteine and allopurinol on myocardial adiponectin content and adiponectin receptor expression in rats with streptozotocininduced diabetes, The FASEB Journal. 2011, 25: 805.4.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats, Anesth Analg. 2011, 112: S-01-S-418.
Xia Z., Irwin M.G., Wong G.T.C., Ng J.K.F., Wang T. and Lei S., "The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats". International Anesthesia Research Society (IARS) 2011 annual meeting. Best of Category Abstract Award, International Anesthesia Research Society (IARS). 2011, 112: S-01-S-418.
Xia Z., Qiao S., Liu Y., Wang T., Mao X.W., Liu H., Wong G.T.C. and Irwin M.G., Antioxidant N-Acetylcysteine Restores Remifentanil Preconditioning Cardioprotection In Rats With Streptozotocin-Induced Diabetes, Anesth Analg. 2011, 112: S-01-S-418.


Researcher : Wang Y

List of Research Outputs

Wang Y., Wong G.T.C., Man K. and Irwin M.G., The Effect of Intravenous and Intrathecal Morphine Preconditioning on Hepatic Ischemia-reperfusion Injury in Normal and Cirrhotic Livers, 15th Research Postgraduate Symposium, Faculty of Medicine, University of Hong Kong. 2010.


Researcher : Wat CY

List of Research Outputs

Chan B.K.B., Tam L.K., Chung Y.F., Wat C.Y., Tsui S.L. and Cheung C.W., Opioids in chronic non-cancer pain, Expert Opinion on Pharmacotherapy. 2011, 12(5): 705-720.


Researcher : Wong GLS

List of Research Outputs

Yuen V.M.Y., Hui T.W.C., Irwin M.G., Yao T.J., Wong G.L.S. and Yuen M.K., Optimal timing for the administration of intranasal dexmedetomidine for premedication in children, Anaesthesia. 2010.


Researcher : Wong GTC

Project Title:The cardiac preconditioning effect of surgery patients
Investigator(s):Wong GTC, Irwin MG, Hiong YT, Das SR
Department:Anaesthesiology
Source(s) of Funding:Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme
Start Date:10/2007


Project Title:Remifentanil Postconditioning Attenuates Cardiac Ischemia-Reperfusion Injury via opioid receptors activation
Investigator(s):Wong GTC, Irwin MG, Xia Z, Jiang L, Li R
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:08/2008
Completion Date:07/2010


Project Title:The effect of short term high dose opioid exposure on the oxidative stress in myocardial tissue
Investigator(s):Wong GTC, Xia Z, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:10/2010


Project Title:Euroanaesthesia 2011 Congress Spinal mu opioid receptor activation is required in remote ischaemic preconditioning of the heart
Investigator(s):Wong GTC
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:06/2011
Completion Date:06/2011


List of Research Outputs

Chou C.W., Wong G.T.C., Lim G., McCabe M.F., Wang S., Irwin M.G. and Mao J., Peripheral nerve injury alters the expression of NF-κB in the rat's hippocampus , Brain Research. 2011, 1378: 66-71.
Irwin M.G. and Wong G.T.C., Neurobiology and Mechanisms of Pain, In: Siu Lun TSUI, Phoon Ping CHEN and Kwok Fu Jacobus NG, Pain Medicine A Multidisplinary Approach. Hong Kong, 2010, 1 - 8.
Jiang L., Wong G.T.C., Lu Y., Xia Z. and Irwin M.G., Remote pharmacological post-conditioning by intrathecal morphine: cardiac protection from spinal opioid receptor activation, Acta Anaesthesiologica Scandinavica . 2010, 54(9): 1097-1104.
Lau T.W., Leung F.K.L., Siu D.C.W., Wong G.T.C. and Luk K.D.K., Geriatric hip fracture clinical pathway: the Hong Kong experience. , Osteoporosis International. 2010 Dec;21(Suppl 4):S573-7. Epub 2010 Nov 6. 2010.
Lau T.W., Leung F.K.L., Siu D.C.W., Wong G.T.C. and Luk K.D.K., Geriatric hip fracture clinical pathway: the Hong Kong experience, Osteoporosis International. 2010, 21(S4): S627-S636.
Mei B., Wong G.T.C., Xia Z. and Irwin M.G., The cardioprotective effect of remifentanil is reduced following high dose exposure, TIVA-TCI 2011 3rd World Congress of Total Intravenous Anaesthesia and target Controlled infusion, Singapore. 2011.
Qiao S., Liu Y., Wang T., Mao X., Wong G.T.C., Xia Z. and Irwin M.G., Remifentanil preconditioning confers cardioprotection via the JAK/STAT but not PI3K/Akt pathway in rats, The FASEB Journal. 2011, 25: 1085.6.
Wang Y., Wong G.T.C., Man K. and Irwin M.G., The Effect of Intravenous and Intrathecal Morphine Preconditioning on Hepatic Ischemia-reperfusion Injury in Normal and Cirrhotic Livers, 15th Research Postgraduate Symposium, Faculty of Medicine, University of Hong Kong. 2010.
Wong G.T.C., Continuous Haemoglobin Monitoring, Second Affiliated Hospital of Anhui Medical University 2010 Forum of Clinical Anaesthesia. 2010.
Wong G.T.C., Intraoperative use of Dexmedetomidine: A practical perspective, Dinner meeting, Hospira Australia.. 2011.
Wong G.T.C., Intrathecal Opioids: Providing more than analgesia, TIVA-TCI 2011 3rd World Congress of Total Intravenous Anaesthesia and target Controlled infusion, Singapore. 2011.
Wong G.T.C., Peer Reviewer of Manuscript, Regulatory Peptides. 2010.
Wong G.T.C., Peer reveiwer, Pharmaceuticals, manuscript 6802, 2011.
Wong G.T.C., Peer reviewer of manuscript, Archives of Medical Research (ARCMED-D-10-00601), 2010.
Wong G.T.C., Peer reviewer, Acta Anaesthesiologica Scandinavica, manuscript AAS-11-0047, 2011.
Wong G.T.C., Peer reviewer, Chinese Medicine, manuscript 4732368125170843, 2011.
Wong G.T.C., Peer reviewer, Health Policy Manuscript 3769, 2010.
Wong G.T.C., Peer reviewer, Hong Kong Medical Journal, Manuscript 3448, 2011.
Wong G.T.C., Peer reviewer, Journal of Anesthesia and Clinical Research Manuscript ACRGROUP-10-95 , 2010.
Wong G.T.C. and Sun N.C.H., Providing perioperative care for patients with hip fractures, Osteoporosis International. 2010, 21(Suppl 4): 547-553.
Wong G.T.C., Huang Z., Ji S. and Irwin M.G., Remifentanil reduces the release of biochemical markers of myocardial damage after coronary artery bypass surgery: a randomized trial, J Cardiothorac Vasc Anesth. 2010, 24(5): 790-796.
Wong G.T.C., Seeing Red: Real Time Haemoglobin Monitoring, Combined Scientific Meeting of the Australian and New Zealand College of Anaesthetists and the Hong Kong College of Anaesthesiologist. 2011.
Xia Z., Irwin M.G., Wong G.T.C., Ng J.K.F., Wang T. and Lei S., "The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats". International Anesthesia Research Society (IARS) 2011 annual meeting. Best of Category Abstract Award, International Anesthesia Research Society (IARS). 2011, 112: S-01-S-418.
Xia Z., Qiao S., Liu Y., Wang T., Mao X.W., Liu H., Wong G.T.C. and Irwin M.G., Antioxidant N-Acetylcysteine Restores Remifentanil Preconditioning Cardioprotection In Rats With Streptozotocin-Induced Diabetes, Anesth Analg. 2011, 112: S-01-S-418.
Xia Z., Huang Z., Liu J., Wong G.T.C. and Irwin M.G., Fructose-1,6-Bisphosphate Reduces Myocardial Injury in Patients Undergoing Heart Valve Surgery, Anesthesiology. 2010, 113: A1541.
Xu J., Xia Z.Y., Irwin M.G., Wong G.T.C. and Xia Z., Propofol Enhances HO-1 Expression and Ameliorates Hyperglycemia Induced Cardiomyocyte Hypertrophy, Anesthesiology. 2010, 113: A1409.
Yang L.Q., Tao K.M., Liu Y.T., Cheung C.W., Wong G.T.C., Lv H., Song J.G., Wu F.X. and Yu W.F., Remifentanil preconditioning reduces hepatic-ischemia reperfusion injury in rats via inducible nitric oxide synthase expression, Anesthesiology. 2011, May 114(5): 1036-1047.


Researcher : Wong K

List of Research Outputs

Huang S.M., Cheung C.W., Chang C.S., Tang C.H., Liu J.F., Lin Y.H., Chen J.H., Ko S.H., Wong K. and Lu D.Y., Phloroglucional derivative MCPP induces cell apoptosis in human colon cancer, Journal of Cellular Biochemistry. 2011, 112(2): 643-652.
Lu D...Y..., Leung Y...M..., Cheung C.W., Chen Y...R... and Wong K., Glial cell line-derived neurotrophic factor induces cell migration and matrix metalloproteinase-13 expression in glioma cells, Biochemical Pharmacology. 2010, 80(8): 1201-1209.
Wong K., Cheung C.W., So E., Leung Y.M. and Cheng T.H., Propofol attenuates apoptosis induced by angiotensin II via the PI3-kinase/Akt pathway in neonatal rat cardiomyocytes, Euroanaesthesia, 2011, Amsterdam, the Netherlands 11-14 June 2011.


Researcher : Wong SJ

List of Research Outputs

Poon J.T.C., Cheng S.W.K., Wong S.J. and Ting A.C.W., Prevalence of abdominal aortic aneurysm in Chinese patients with severe coronary artery disease, ANZ Journal of Surgery. 2010, 80(9): 630-633.


Researcher : Xia Z

Project Title:Nitrate tolerance compromises propofol protection of the endothelium against inflammation: The role of PKC-beta2 and NADPH oxidase interaction
Investigator(s):Xia Z
Department:Anaesthesiology
Source(s) of Funding:SCA Research Starter and MidCareer Grants
Start Date:07/2008


Project Title:L-Arginine Exacerbates TNF-Alpha Toxicity in Endothelial cells and Cardiomyocytes: Role of PKC-β2 activation
Investigator(s):Xia Z, Irwin MG, Vanhoutte PMGR
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2009
Completion Date:10/2010


Project Title:Synergy between N-acetylcysteine, allopurinol and/or PKC-beta inhibition attenuates diabetic cardiomyopathy in the rat
Investigator(s):Xia Z, Irwin MG, Rong J, Vanhoutte PMGR, Wang Y
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


Project Title:PKC-beta2 Over Expression in the Myocardium of Diabetic Rats Compromises Opioid Agonist-Induced Cardioprotection
Investigator(s):Xia Z, Irwin MG, Wong GTC
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010
Completion Date:02/2011


Project Title:The role of iNOS in ischemic postconditioning cardioprotection in normal and diabetic rodents
Investigator(s):Xia Z, Irwin MG, Vanhoutte PMGR, Wang Y, Wong GTC
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2010


Project Title:American Society of Anesthesiologists Annual Meeting 2010 Fructose-1,6-Bisphosphate Reduces Myocardial Injury In Patients Undergoing Heart Valve Surgery
Investigator(s):Xia Z
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Grants for Teaching Staff
Start Date:10/2010
Completion Date:10/2010


Project Title:Effects and Mechanism of Adiponectin on Diabetic Heart Sensitivity to Ischemic Postconditioning
Investigator(s):Xia Z, Xu A, Irwin MG, Vanhoutte PMGR, Ng JKF, Wang Y
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2011


List of Research Outputs

Fan Q., Yang X.C., Liu Y., Wang L.F., Liu S.H., Ge Y.G., Chen M.L., Wang W., Zhang L.K., Irwin M.G. and Xia Z., Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans, Clinical Science (Lond). 2010, 120(6): 251-261.
Gao X., Xu Y., Lei S., Liu Y. and Xia Z., Synergy Of N-Acetylcysteine And Allopurinol Improves Systemic Oxygen Delivery In Rats With Streptozotocin-Induced Diabetes, The FASEB Journal. 2011, 25: 805.2.
Guo Y., Wu X.Q., Zhang C., Liao Z.X., Wu Y., Xia Z. and Wang H., Effect of indole-3-carbinol on ethanol-induced liver injury and acetaldehyde-stimulated hepatic stellate cells activation using precision-cut rat liver slices, Clinical and Experimental Pharmacology and Physiology. 2010, 37(12): 1107-13.
Jiang L., Wong G.T.C., Lu Y., Xia Z. and Irwin M.G., Remote pharmacological post-conditioning by intrathecal morphine: cardiac protection from spinal opioid receptor activation, Acta Anaesthesiologica Scandinavica . 2010, 54(9): 1097-1104.
Lei S., Liu Y., Liu H., Xia Z.Y., Irwin M.G. and Xia Z., N-acetylcysteine inhibits NADPH oxidase activation and attenuates lipid peroxidation in the heart, lung, liver and kidney in streptozotocin-induced diabetic rats, The FASEB Journal. 2011, 25: 805.1.
Liu K.X., Li C., Li Y.S., Yuan B.L., Xu M., Xia Z. and Huang W.Q., Proteomic analysis of intestinal ischemia/reperfusion injury and ischemic preconditioning in rats reveals the protective role of aldose reductase, Proteomics. 2010, 10(24): 4463-75.
Mao X., Ng J.K.F., Irwin M.G., Vanhoutte P.M.G.R. and Xia Z., N-Acetylcysteine Enhances Cardiac HO-1 Protein Expression and Antioxidant Capacity in Diabetic Rats, Anesthesiology. 2010, 112: in press.
Mei B., Wong G.T.C., Xia Z. and Irwin M.G., The cardioprotective effect of remifentanil is reduced following high dose exposure, TIVA-TCI 2011 3rd World Congress of Total Intravenous Anaesthesia and target Controlled infusion, Singapore. 2011.
Qiao S., Liu Y., Wang T., Mao X., Wong G.T.C., Xia Z. and Irwin M.G., Remifentanil preconditioning confers cardioprotection via the JAK/STAT but not PI3K/Akt pathway in rats, The FASEB Journal. 2011, 25: 1085.6.
Wang M., Peng J., Wang R., Zhao L. and Xia Z., TRPV1 Agonist Capsaicin Attenuates Lung Ischemia-Reperfusion Injury in Rabbits, Journal of Surgical Research . 2010.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., Effects of N-acetylcysteine and allopurinol on myocardial adiponectin content and adiponectin receptor expression in rats with streptozotocininduced diabetes, The FASEB Journal. 2011, 25: 805.4.
Wang T., Qiao S., Lei S., Liu Y., Ng J.K.F., Irwin M.G. and Xia Z., The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats, Anesth Analg. 2011, 112: S-01-S-418.
Xia Z., Irwin M.G., Wong G.T.C., Ng J.K.F., Wang T. and Lei S., "The Synergy of Antioxidants N-Acetylcysterine And Allopurinol Enhances Cardiac Adiponectin Activation And Reduces Postischemic Myocardial Reperfusion Injury In Streptozotocin -Induced Diabetic Rats". International Anesthesia Research Society (IARS) 2011 annual meeting. Best of Category Abstract Award, International Anesthesia Research Society (IARS). 2011, 112: S-01-S-418.
Xia Z., Qiao S., Liu Y., Wang T., Mao X.W., Liu H., Wong G.T.C. and Irwin M.G., Antioxidant N-Acetylcysteine Restores Remifentanil Preconditioning Cardioprotection In Rats With Streptozotocin-Induced Diabetes, Anesth Analg. 2011, 112: S-01-S-418.
Xia Z., Effects and mechanism of StAR on adrenal gland dysfunction , Wuhan University PhD thesis (external examiner). 2011.
Xia Z., External Grant reviewer, National Natural Science Foundation of China (NSFC) (reviewed 15 grants for NSFC). 2011.
Xia Z., Huang Z., Liu J., Wong G.T.C. and Irwin M.G., Fructose-1,6-Bisphosphate Reduces Myocardial Injury in Patients Undergoing Heart Valve Surgery, Anesthesiology. 2010, 113: A1541.
Xia Z., Journal of Diabetes & Metabolism. 2011.
Xia Z. and Vanhoutte P.M.G.R., Nitric oxide and protection against cardiac ischemia, Current Pharmaceutical Design. 2011, 17(18): 1774-1782.
Xia Z., Peer Reviewer, Injury. 2011.
Xia Z., Peer reviewer, Anesthesiology. 2011.
Xia Z., Peer reviewer, Biochemical Pharmacology. 2011.
Xia Z., Peer reviewer, Canadian Journal of Anesthesia. 2011.
Xia Z., Peer reviewer, PLoS ONE. 2011.
Xia Z., Quercetin protective effects on kidney function in Type 2 diabetes, Wuhan University PhD thesis (external examiner). 2011.
Xia Z., Study on mechanisms of the role of oxidative stress and PKC-β2 activation in early cardiomyopathy of diabetic rats , Wuhan University PhD Thesis. 2011.
Xia Z.Y., Zhang L., Wu Y., Xu J. and Xia Z., Ginsenoside Rb1 Preconditioning Attenuates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats, Anesthesiology. 2010, 113: A917.
Xu B., Gao X., Xu J., Lei S., Xia Z.Y., Xu Y. and Xia Z., Ischemic postconditioning attenuates lung reperfusion injury and reduces systemic proinflammatory cytokine release via heme oxygenase 1, Journal of Surgical Research. 2011, 166(2): e157-64.
Xu J., Xia Z.Y., Irwin M.G., Wong G.T.C. and Xia Z., Propofol Enhances HO-1 Expression and Ameliorates Hyperglycemia Induced Cardiomyocyte Hypertrophy, Anesthesiology. 2010, 113: A1409.
Xu Y., Gao X., Xu B., Liu H., Irwin M.G. and Xia Z., Allopurinol Attenuates Left Ventricular Dysfunction In The Early Stage of Streptozotocin-Induced Diabetes In Rats, The FASEB Journal. 2011, 25: Ib374.
Zhu X.H., Yuan H.J., Wu Y.N., Kang Y., Jiao J.J., Gao W.Z., Liu Y.X., Lou J.S. and Xia Z., Non-invasive limb ischemic pre-conditioning reduces oxidative stress and attenuates myocardium ischemia-reperfusion injury in diabetic rats, Free Radical Research. 2011, 45(2): 201-10.


Researcher : Yong BH

List of Research Outputs

Chan S.C., Lo C.M., Ng K.K.C., Ng I.O.L., Yong B.H. and Fan S.T., Portal inflow and pressure changes in right liver living donor liver transplantation including the middle hepatic vein, Liver Transplantation. 2011, 17(2): 115-121.


Researcher : Yuen MK

List of Research Outputs

Yuen V.M.Y., Hui T.W.C., Irwin M.G., Yao T.J., Wong G.L.S. and Yuen M.K., Optimal timing for the administration of intranasal dexmedetomidine for premedication in children, Anaesthesia. 2010.


Researcher : Yuen VMY

List of Research Outputs

Cheung C.W., Ng J.K.F., Liu J., Yuen V.M.Y., Ho M.H.A. and Irwin M.G., Analgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia, British Journal of Anaestheisa.. 2011, 107(3): 430-437.
Yuen V.M.Y., Hui T.W.C., Irwin M.G., Yao T.J., Wong G.L.S. and Yuen M.K., Optimal timing for the administration of intranasal dexmedetomidine for premedication in children, Anaesthesia. 2010.


Researcher : Zhang Y

List of Research Outputs

Zhang Y., Lu Y., Mei B., Zhou Y.M., Chen Z.W. and Wong T.M., Intracerebroventricular administration of morphone confers remote cardioprotecion - role of opioid receptors and calmodulin, European J Pharmacology. 2011, 656(1-3): 74-80.


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