HKU-PASTEUR RESEARCH CENTRE LIMITED
| Researcher : Bruzzone R |
| List of Research Outputs |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Leung H.L., Li P.H., Kien F.S., Dutry I.C.A., Callendret B., Escriou N., Altmeyer R.M., Nal-Rogier B.T.M., Daeron M., Bruzzone R. and Peiris J.S.M., Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcgR Pathway, Journal of Virology. 2011, 85. |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Kien F.S., Li P.H., Dutry I.C.A., Bruzzone R., Peiris J.S.M., Nal-Rogier B.T.M. and Altmeyer R.M., Sars Cov Subunit Vaccine: Antibody-mediated Neutralisation And Enhancement., In: Jaume M, Yip MS, Kam YW, Cheung CY, Kien F, Roberts A, Li PH, Dutry I, Escriou N, Daeron M, Bruzzone R, Subbarao K, Peiris JS, Nal B, Altmeyer R, Hong Kong Med J.. Hong Kong, 2012, 18: Suppl 2:31-6. |
| Kudelko M.A., Brault J.B., Kwok K.T.H., Pardigon N., Peiris J.S.M., Bruzzone R., Despres P., Nal-Rogier B.T.M. and Wang P., Class II ADP-ribosylation Factors Are Required for Efficient Secretion of Dengue Viruses, The Journal of Biological Chemistry. 2012, 287 (1): 767-777. |
| Yip M.S., Cheung C.Y., Li P.H., Bruzzone R., Peiris J.S.M. and Jaume M.D.A., Investigation of Antibody-Dependent Enhancement (ADE) of SARS Coronavirus Infection and Its Role in Pathogenesis of SARS (RFCID grant 09080872), Health Research Symposium 2010: “Improving health and recognising excellence”. Food and Health Bureau, the Government of the Hong Kong Special Administrative Region. 2011. |
| Researcher : Dutry ICA |
| List of Research Outputs |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Leung H.L., Li P.H., Kien F.S., Dutry I.C.A., Callendret B., Escriou N., Altmeyer R.M., Nal-Rogier B.T.M., Daeron M., Bruzzone R. and Peiris J.S.M., Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcgR Pathway, Journal of Virology. 2011, 85. |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Kien F.S., Li P.H., Dutry I.C.A., Bruzzone R., Peiris J.S.M., Nal-Rogier B.T.M. and Altmeyer R.M., Sars Cov Subunit Vaccine: Antibody-mediated Neutralisation And Enhancement., In: Jaume M, Yip MS, Kam YW, Cheung CY, Kien F, Roberts A, Li PH, Dutry I, Escriou N, Daeron M, Bruzzone R, Subbarao K, Peiris JS, Nal B, Altmeyer R, Hong Kong Med J.. Hong Kong, 2012, 18: Suppl 2:31-6. |
| Researcher : Garcia JC |
| List of Research Outputs |
| Chao B., Tong X.K., Tang W., Li D.W., He P.L., Garcia J.C., Gao A.H., Yang L., Li J., Nan F.J., Jacobs M., Altmeyer R.M., Zuo J.P. and Hu Y.H., Discovery and Optimization of 2,4-Diaminoquinazoline Derivatives As a New Class of Potent Dengue Virus Inhibitors. , J Med Chem. . 2012, 12: 3135-43. |
| Desvaux S., Garcia J.C., Nguyen T.D., Reid S., Ngoc A.B., Roger F., Fenwick F., Peiris J.S.M. and Ellis T., Evaluation of serological tests for H5N1 avian influenza on field samples from domestic poultry populations in Vietnam: consequences for surveillance. , Veterinary Microbiology. . ELSEVIER, 2012, 156: 277-84. |
| Garcia J.C., Global Is Not Enough: Universal Biosafety. Can It Be the Next New Culture? , Biosafety . 2012, 1: e101. |
| Garcia J.C., Lai J.C.C., Buchy P., Cavailler P., De Jong M. and Peiris J.S.M., “Pseudotyped Lentiviral Particles: a “Swiss Army Knife” for Influenza Research”, , first Scientific International Meeting of the Young Researchers from the Institut Pasteur International Network “Challenges in Global Health: Opportunities for Institut Pasteur International Network”,. 2011. |
| Lai J.C.C., Garcia J.C., Dyason J.C., Böhm R., Madge P.D., Rose F.J., Nicholls J.M., Peiris J.S.M., Haselhorst T. and von Itzstein M., A secondary sialic acid binding site on influenza virus neuraminidase. Fact or fiction?, Angew Chem Int Ed Engl. . 2012, 51: 2221-4. |
| Nicholls J.M., Lai J.C.C. and Garcia J.C., Investigating the interaction between influenza and sialic acid – making and breaking the link., In: M. von Itzstein , Milestones in Drug Therapy. Influenza Virus Sialidase - A Drug Discovery Target.. Basel, Springer Basel AG, 2011, 31-45. |
| Trevennec K., Leger L., Lyazrhi F., Baudon E., Cheung C.Y., Roger F. and Garcia J.C., Transmission of pandemic influenza H1N1 (2009) in Vietnamese swine in 2009-2010., Influenza Other Respiratory Viruses. 2011. |
| Trevennec K.A.R.E.N., Chevalier V., Grosbois V., Garcia J.C., Ho Thu H., Berthouly–Salazar C., Peiris J.S.M. and Roger F., Looking for avian influenza in remote areas. A case study in Northern Vietnam., Acta Tropica. 2011, 120: 160-6. |
| Researcher : Jaume MDA |
| List of Research Outputs |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Leung H.L., Li P.H., Kien F.S., Dutry I.C.A., Callendret B., Escriou N., Altmeyer R.M., Nal-Rogier B.T.M., Daeron M., Bruzzone R. and Peiris J.S.M., Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcgR Pathway, Journal of Virology. 2011, 85. |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Kien F.S., Li P.H., Dutry I.C.A., Bruzzone R., Peiris J.S.M., Nal-Rogier B.T.M. and Altmeyer R.M., Sars Cov Subunit Vaccine: Antibody-mediated Neutralisation And Enhancement., In: Jaume M, Yip MS, Kam YW, Cheung CY, Kien F, Roberts A, Li PH, Dutry I, Escriou N, Daeron M, Bruzzone R, Subbarao K, Peiris JS, Nal B, Altmeyer R, Hong Kong Med J.. Hong Kong, 2012, 18: Suppl 2:31-6. |
| Yip M.S., Cheung C.Y., Li P.H., Bruzzone R., Peiris J.S.M. and Jaume M.D.A., Investigation of Antibody-Dependent Enhancement (ADE) of SARS Coronavirus Infection and Its Role in Pathogenesis of SARS (RFCID grant 09080872), Health Research Symposium 2010: “Improving health and recognising excellence”. Food and Health Bureau, the Government of the Hong Kong Special Administrative Region. 2011. |
| Researcher : Kien FS |
| List of Research Outputs |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Leung H.L., Li P.H., Kien F.S., Dutry I.C.A., Callendret B., Escriou N., Altmeyer R.M., Nal-Rogier B.T.M., Daeron M., Bruzzone R. and Peiris J.S.M., Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcgR Pathway, Journal of Virology. 2011, 85. |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Kien F.S., Li P.H., Dutry I.C.A., Bruzzone R., Peiris J.S.M., Nal-Rogier B.T.M. and Altmeyer R.M., Sars Cov Subunit Vaccine: Antibody-mediated Neutralisation And Enhancement., In: Jaume M, Yip MS, Kam YW, Cheung CY, Kien F, Roberts A, Li PH, Dutry I, Escriou N, Daeron M, Bruzzone R, Subbarao K, Peiris JS, Nal B, Altmeyer R, Hong Kong Med J.. Hong Kong, 2012, 18: Suppl 2:31-6. |
| Researcher : Kwok KTH |
| List of Research Outputs |
| Kudelko M.A., Brault J.B., Kwok K.T.H., Pardigon N., Peiris J.S.M., Bruzzone R., Despres P., Nal-Rogier B.T.M. and Wang P., Class II ADP-ribosylation Factors Are Required for Efficient Secretion of Dengue Viruses, The Journal of Biological Chemistry. 2012, 287 (1): 767-777. |
| Researcher : Lai JCC |
| List of Research Outputs |
| Garcia J.C., Lai J.C.C., Buchy P., Cavailler P., De Jong M. and Peiris J.S.M., “Pseudotyped Lentiviral Particles: a “Swiss Army Knife” for Influenza Research”, , first Scientific International Meeting of the Young Researchers from the Institut Pasteur International Network “Challenges in Global Health: Opportunities for Institut Pasteur International Network”,. 2011. |
| Nicholls J.M., Lai J.C.C. and Garcia J.C., Investigating the interaction between influenza and sialic acid – making and breaking the link., In: M. von Itzstein , Milestones in Drug Therapy. Influenza Virus Sialidase - A Drug Discovery Target.. Basel, Springer Basel AG, 2011, 31-45. |
| Researcher : Li PH |
| List of Research Outputs |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Leung H.L., Li P.H., Kien F.S., Dutry I.C.A., Callendret B., Escriou N., Altmeyer R.M., Nal-Rogier B.T.M., Daeron M., Bruzzone R. and Peiris J.S.M., Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcgR Pathway, Journal of Virology. 2011, 85. |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Kien F.S., Li P.H., Dutry I.C.A., Bruzzone R., Peiris J.S.M., Nal-Rogier B.T.M. and Altmeyer R.M., Sars Cov Subunit Vaccine: Antibody-mediated Neutralisation And Enhancement., In: Jaume M, Yip MS, Kam YW, Cheung CY, Kien F, Roberts A, Li PH, Dutry I, Escriou N, Daeron M, Bruzzone R, Subbarao K, Peiris JS, Nal B, Altmeyer R, Hong Kong Med J.. Hong Kong, 2012, 18: Suppl 2:31-6. |
| Yip M.S., Cheung C.Y., Li P.H., Bruzzone R., Peiris J.S.M. and Jaume M.D.A., Investigation of Antibody-Dependent Enhancement (ADE) of SARS Coronavirus Infection and Its Role in Pathogenesis of SARS (RFCID grant 09080872), Health Research Symposium 2010: “Improving health and recognising excellence”. Food and Health Bureau, the Government of the Hong Kong Special Administrative Region. 2011. |
| Researcher : Nal-Rogier BTM |
| List of Research Outputs |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Kien F.S., Li P.H., Dutry I.C.A., Bruzzone R., Peiris J.S.M., Nal-Rogier B.T.M. and Altmeyer R.M., Sars Cov Subunit Vaccine: Antibody-mediated Neutralisation And Enhancement., In: Jaume M, Yip MS, Kam YW, Cheung CY, Kien F, Roberts A, Li PH, Dutry I, Escriou N, Daeron M, Bruzzone R, Subbarao K, Peiris JS, Nal B, Altmeyer R, Hong Kong Med J.. Hong Kong, 2012, 18: Suppl 2:31-6. |
| Researcher : Peiris JSM |
| Project Title: | IV International Symposium on Respiratory Viral Infections The Influenza Disease Burden in Hong Kong: the Rates of Hospitalisation in Children |
| Investigator(s): | Peiris JSM |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2001 |
| Project Title: | Influenza pandemic preparedness in Asia (Research collaboration with national Institute of Allergy and Infectious Diseases (NIAID), St. Jude Children's Research Hospital, Inc. (SJCRH) and The University of Hong Kong) |
| Investigator(s): | Peiris JSM, Guan Y |
| Department: | Microbiology |
| Source(s) of Funding: | National Institutes of Health, US Department of Health and Human Services - General Award |
| Start Date: | 04/2003 |
| Project Title: | Virus-cell interaction and the pathogenesis of SARS |
| Investigator(s): | Peiris JSM |
| Department: | Microbiology |
| Source(s) of Funding: | VCO SARS Research Fund |
| Start Date: | 07/2003 |
| Project Title: | Viral determinants underlying the increased secretion of pro-inflammatory cytokines in H5N1 infected human macrophages: a mechanism for the unusual severity of human H5N1 disease? |
| Investigator(s): | Peiris JSM, Guan Y, Lau ASY, Poon LLM |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2003 |
| Project Title: | The macrophage in the pathogenesis of Severe Acute Respiratory Syndrome Coronavirus infection |
| Investigator(s): | Peiris JSM |
| Department: | Microbiology |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 12/2005 |
| Project Title: | Mass Tag PCR: A novel, multiplex and potentially sensitive approach for the rapid detection of respiratory pathogens |
| Investigator(s): | Peiris JSM, Chiu SSS, Cheung CY |
| Department: | Microbiology |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 06/2006 |
| Project Title: | The pathogenesis of avian influenza A H5N1 in humans: macrophage and epithelial cell-virus interactions in vitro and ex-vivo |
| Investigator(s): | Peiris JSM |
| Department: | Microbiology |
| Source(s) of Funding: | The Wellcome Trust - General Award |
| Start Date: | 01/2007 |
| Project Title: | Communicable Diseases Surveillance and Response (CSR) - Standardization and shipment of PCR diagnostic kit for Avian Influenza detection to Member countries (viz: Bangladesh, Indonesia, Myanmar, Sri Lanka and Thailand) |
| Investigator(s): | Peiris JSM |
| Department: | Microbiology |
| Source(s) of Funding: | Collaborating Project Fund |
| Start Date: | 06/2007 |
| Project Title: | Control of Pandemic and Inter-pandemic Influenza |
| Investigator(s): | Peiris JSM, Guan Y, Yuen KY, Chen H, Leung GM, Lau YL |
| Department: | Microbiology |
| Source(s) of Funding: | Areas of Excellence Scheme |
| Start Date: | 01/2008 |
| Project Title: | The role of Toll-like receptor 10 (TLR10) as an innate immune sensor for respiratory viral infections |
| Investigator(s): | Peiris JSM, Lee MY, Nicholls JM |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2011 |
| List of Research Outputs |
| Desvaux S., Garcia J.C., Nguyen T.D., Reid S., Ngoc A.B., Roger F., Fenwick F., Peiris J.S.M. and Ellis T., Evaluation of serological tests for H5N1 avian influenza on field samples from domestic poultry populations in Vietnam: consequences for surveillance. , Veterinary Microbiology. . ELSEVIER, 2012, 156: 277-84. |
| Garcia J.C., Lai J.C.C., Buchy P., Cavailler P., De Jong M. and Peiris J.S.M., “Pseudotyped Lentiviral Particles: a “Swiss Army Knife” for Influenza Research”, , first Scientific International Meeting of the Young Researchers from the Institut Pasteur International Network “Challenges in Global Health: Opportunities for Institut Pasteur International Network”,. 2011. |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Leung H.L., Li P.H., Kien F.S., Dutry I.C.A., Callendret B., Escriou N., Altmeyer R.M., Nal-Rogier B.T.M., Daeron M., Bruzzone R. and Peiris J.S.M., Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcgR Pathway, Journal of Virology. 2011, 85. |
| Lai J.C.C., Garcia J.C., Dyason J.C., Böhm R., Madge P.D., Rose F.J., Nicholls J.M., Peiris J.S.M., Haselhorst T. and von Itzstein M., A secondary sialic acid binding site on influenza virus neuraminidase. Fact or fiction?, Angew Chem Int Ed Engl. . 2012, 51: 2221-4. |
| Yip M.S., Cheung C.Y., Li P.H., Bruzzone R., Peiris J.S.M. and Jaume M.D.A., Investigation of Antibody-Dependent Enhancement (ADE) of SARS Coronavirus Infection and Its Role in Pathogenesis of SARS (RFCID grant 09080872), Health Research Symposium 2010: “Improving health and recognising excellence”. Food and Health Bureau, the Government of the Hong Kong Special Administrative Region. 2011. |
| Researcher : Wang P |
| List of Research Outputs |
| Kudelko M.A., Brault J.B., Kwok K.T.H., Pardigon N., Peiris J.S.M., Bruzzone R., Despres P., Nal-Rogier B.T.M. and Wang P., Class II ADP-ribosylation Factors Are Required for Efficient Secretion of Dengue Viruses, The Journal of Biological Chemistry. 2012, 287 (1): 767-777. |
| Researcher : Yen H |
| Project Title: | The role of balanced hemagglutinin-neuraminidase activity on the genesis of transmissible NA inhibitor-resistant variants in seasonal and novel pandemic influenza A H1N1 viruses |
| Investigator(s): | Yen H, Peiris JSM |
| Department: | Microbiology |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 01/2010 |
| Project Title: | Role of influenza hemagglutinin glycoprotein in activation of dendritic cells and induction of effective immune response through C-type lectin receptors |
| Investigator(s): | Yen H, Peiris JSM, Tu W |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2011 |
| Project Title: | Evaluating effect of pandemic H1N1 matrix protein 1 on viral replication in vitro |
| Investigator(s): | Yen H, Peiris JSM |
| Department: | School of Public Health |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2012 |
| List of Research Outputs |
| Yen H., Antiviral Research. 2012. |
| Researcher : Yip MS |
| Project Title: | Role of type II collagen cleavage and immune responses in intervertebral disc degeneration in vivo |
| Investigator(s): | Yip MS, Chan D |
| Department: | Biochemistry |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2012 |
| List of Research Outputs |
| Jaume M.D.A., Yip M.S., Cheung C.Y., Leung H.L., Li P.H., Kien F.S., Dutry I.C.A., Callendret B., Escriou N., Altmeyer R.M., Nal-Rogier B.T.M., Daeron M., Bruzzone R. and Peiris J.S.M., Anti-Severe Acute Respiratory Syndrome Coronavirus Spike Antibodies Trigger Infection of Human Immune Cells via a pH- and Cysteine Protease-Independent FcgR Pathway, Journal of Virology. 2011, 85. |
| Yip M.S., Cheung C.Y., Li P.H., Bruzzone R., Peiris J.S.M. and Jaume M.D.A., Investigation of Antibody-Dependent Enhancement (ADE) of SARS Coronavirus Infection and Its Role in Pathogenesis of SARS (RFCID grant 09080872), Health Research Symposium 2010: “Improving health and recognising excellence”. Food and Health Bureau, the Government of the Hong Kong Special Administrative Region. 2011. |