DEPT OF CLINICAL ONCOLOGY
| Researcher : Au GKH |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| Researcher : CAO T |
| List of Research Outputs |
| CAO T., Xiang D., Liu B., Huang T., Tan B., Zeng C., Wang Z., Ming X., ZHANG L., Jin G., Li F., Wu J., Guan X., Lu D. and Fu L., FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma, Oncotarget. 2017, 8: 65957-65968. |
| MING X., Zhang X., CAO T., ZHANG L., QI J., TANG X., CUI Y., Zhang B., Li Y., Qin Y. and Guan X., RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression, Theranostics. 2018, 8: 185-198. |
| Researcher : CHAI WY |
| List of Research Outputs |
| CHAI W.Y., Cheung A.K.L., Dai W., Ko J.M.Y., Lee N.P.Y., Chan K.T., Law S.Y.K. and Lung M.L., Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma, Cancer Biomarkers. 2018, 21: 583-590. |
| Researcher : CHOI SS.A |
| List of Research Outputs |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Researcher : CUI Y |
| List of Research Outputs |
| MING X., Zhang X., CAO T., ZHANG L., QI J., TANG X., CUI Y., Zhang B., Li Y., Qin Y. and Guan X., RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression, Theranostics. 2018, 8: 185-198. |
| Researcher : Chan KC |
| List of Research Outputs |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Researcher : Chan OSH |
| List of Research Outputs |
| Chan O.S.H., Lee V.H.F., Mok T.S.K., Mo F., Chang T.Y.A. and Yeung M.W.R., The Role of Radiotherapy in Epidermal Growth Factor Receptor Mutation-positive Patients with Oligoprogression: A Matched-cohort Analysis, Clinical Oncology. 2017, 29: 568-575. |
| Chang T.Y.A., Chan O.S.H., Soong S.I., Hung A.W.M., Chan L.L.K. and Yeung M.W.R., Evaluating clinical outcome and toxicity for stereotactic body radiotherapy in oligometastatic lung disease, In: Louisa C Lui, Kam-Hung Wong, Rebecca Yeung and Joav Merrick, In Palliative Care: Oncology Experience from Hong Kong. 2017, 135-154. |
| Researcher : Chan SK |
| List of Research Outputs |
| Lam T.C., Chan S.K. and Choi C.W., Mitotic count and male gender are predictors of radiological recurrence after surgical excision of meningioma, The 14th Meeting of the Asian Society for Neuro-Oncology (ASNO 2017). 2017. |
| Researcher : Chan WLW |
| List of Research Outputs |
| Lau K.S., Lam K.O., Chan W.L.W., Lee V.H.F., Kwong D.L.W. and Leung T.W., S-1 Versus S-1 Plus Cisplatin as First-line Treatment for Metastatic Gastric Cancer, Hong Kong Journal of Radiology. 2017, 318-322. |
| Wong K.P., Chan W.L.W. and Lang H.H.B., Should surgery be performed in patient with marginal resectable anaplastic thyroid cancer? (ePoster presentation), The 3rd World Congress on Thyroid Cancer, Boston, USA, 28-29 July 2017. |
| Researcher : Chang TYA |
| List of Research Outputs |
| Chan O.S.H., Lee V.H.F., Mok T.S.K., Mo F., Chang T.Y.A. and Yeung M.W.R., The Role of Radiotherapy in Epidermal Growth Factor Receptor Mutation-positive Patients with Oligoprogression: A Matched-cohort Analysis, Clinical Oncology. 2017, 29: 568-575. |
| Chang T.Y.A., Tan L.T., Duke S. and Ng W.T., Challenges for Quality Assurance of Target Volume Delineation in Clinical Trials, Frontiers in Oncology. 2017, 7. |
| Chang T.Y.A., Chan O.S.H., Soong S.I., Hung A.W.M., Chan L.L.K. and Yeung M.W.R., Evaluating clinical outcome and toxicity for stereotactic body radiotherapy in oligometastatic lung disease, In: Louisa C Lui, Kam-Hung Wong, Rebecca Yeung and Joav Merrick, In Palliative Care: Oncology Experience from Hong Kong. 2017, 135-154. |
| Yang L., Xu Z.Y., Li J.S., Chen Z.J., Lee V.H.F., Lam K.O., Lam T.C., Chiang C.L., Chang T.Y.A., Huse V., Kwong D.L.W. and Lee W.M.A., The feasibility and short-term efficacy of induction chemotherapy with cisplatin and capecitabine followed by concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma, The 25th Annual Scientific Meeting, Hong Kong College of Radiologists, Hong Kong. 2017. |
| Researcher : Cheng CK |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| Researcher : Cheng HC |
| List of Research Outputs |
| Cheung K.M., Ngan K.C.R., Chow J.C.H., Lee T.Y., Li K.W.S., Cheng H.C., Leung C.W.L., Yiu H.H.Y., Yau S., Au J.S.K. and Wong K.H., Can Neoadjuvant Chemotherapy before Definitive Surgery Improve Outcome in Operable Stage IVA Oral Cavity Cancers?, Hong Kong Journal of Radiology. 2018, 21: 124-131. |
| Researcher : Cheung AKL |
| Project Title: | Investigation of the role of Epstein-Barr Virus in epigenetic regulation in nasopharyngeal carcinoma |
| Investigator(s): | Cheung AKL, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2012 |
| List of Research Outputs |
| CHAI W.Y., Cheung A.K.L., Dai W., Ko J.M.Y., Lee N.P.Y., Chan K.T., Law S.Y.K. and Lung M.L., Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma, Cancer Biomarkers. 2018, 21: 583-590. |
| DENG M., Cheung A.K.L., Dai W. and Lung M.L., Functional and molecular analysis of the loss-of-function somatic mutations in two NF-κB pathway inhibitors: NFKBIA and CYLD in nasopharyngeal carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members Resulting in Cisplatin Resistance in Nasopharyngeal Carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members in Nasopharyngeal Carcinoma., The 76th Annual Meeting of the Japanese Cancer Association, Tokyo, Japan. Sept 28-30, 2017.. 2017. |
| LEONG M.L., Cheung A.K.L., Kwok C.T.T. and Lung M.L., Functional Characterization of a candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Researcher : Chiang CL |
| Project Title: | Treatment outcomes in regractory mCRC patients |
| Investigator(s): | Chiang CL, Lam KO |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Bayer HealthCare Limited |
| Start Date: | 04/2017 |
| Project Title: | ASTRO's 59th Annual Meeting; Albumin-Bilirubin (ALBI) versus Child-Pugh (CP) Score as a predictor of survival after Stereotactic Body Radiotherapy (SBRT) in Hepatocellular Carcinoma (HCC) |
| Investigator(s): | Chiang CL |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2017 |
| Project Title: | Prospective Multi-center Single Arm Phase II Trial of External Radiotherapy plus Endorectal Brachytherapy Boost as Radical Treatment in Rectal Cancer Patients |
| Investigator(s): | Chiang CL, Lam KO, Foo CC, Chiu WHK, Choi CW |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 01/2018 |
| Project Title: | Cost-effectiveness of anti-EGFR antibodies as first-line treatment in RAS wild type (WT) metastatic colorectal cancer (mCRC) in Hong Kong |
| Investigator(s): | Chiang CL, Choi CW, Lam KO, Lee VHF, Wong OL |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Mini Grant |
| Start Date: | 04/2018 |
| List of Research Outputs |
| Chiang C.L., Choi C.W., Mui W.H. and So T.H., 261OCost-effectiveness analysis of additional abiraterone for hormone-sensitive metastatic prostatic cancer treated with androgen deprivation therapy (ADT), Annals of Oncology. 2017, 28: 80. |
| Chiang C.L., Clinical and Research Development on Immuno-oncology in Hong Kong, Immuno-Oncology in Bladder Cancer: What have we learned and next steps, Hong Kong, 22 Sep 2017. 2017. |
| Chiang C.L., Is there still a role of Radiotherapy in Locally Advanced Pancreatic Cancer? Asia-Pacific Gastroenterology Cancer Summit, APGCS2018, Singapore. 2018. |
| Chiang C.L., Lo S.H. and Agarwal A., Prognostic Factors For Survival Prediction in Advanced Cancer patients And Development of a Simple Survival Prediction Tool for Application in A Community Palliative Care Setting, In: Louisa C Lui, Kam-Hung Wong, Rebecca Yeung and Joav Merrick, In Palliative Care: Oncology Experience From Hong Kong. 2017, 91-110. |
| Chiang C.L., So T.H., Chen Z.J., Lee V.H.F. and Lee W.M.A., Pursuit of Excellence in the Management of Nasopharyngeal Carcinoma (NPC), International Journal of Head and Neck Science. 2017, 1(4): 199-211. |
| Chiang C.L., Recent Advance in Management on Pancreatic Cancer, Multi-specialty Medical Mega Conference Eighth Round, Hong Kong, 22 Apr 2018. 2018. |
| Chiang C.L., Recent Advance in Radiotherapy of Rectal Cancer, Multi-specialty Medical Mega Conference Eighth Round, Hong Kong, 22 Apr 2018. 2018. |
| Chiang C.L., Recent Advance in radiotherapy of rectal cancer, 25th Annual Scientific Meeting of Hong Kong College of Radiologists, Hong Kong, 18 Nov 2017. 2017. |
| Chiang C.L., Recent Advance in radiotherapy of rectal cancer, 25th Annual Scientific Meeting of Hong Kong College of Radiologists, Hong Kong, 18 November 2017. 2017. |
| Chiang C.L., SBRT for Locally Advanced CA Pancreas, HKSBRT Study Group First Scientific Meeting, Hong Kong, 30 Jun 2018. 2018. |
| Chiang C.L., Lee F.A.S., Wong Y.W.V., Poon C.M., Choi C.K.K., Wong C.S.F., Sze W.K. and Tung S.Y., Short-course Preoperative Radiotherapy with Delayed Surgery for Locally Advanced Rectal Cancer, Hong Kong Journal of Radiology. 2017, 20(4): 312-317. |
| Chiang C.L., Yeung C.S.Y., Wong M.Y.P., Lee W.Y., Lee V.H.F., Lee F.A.S. and Wong F.C.S., Stereotactic Body Radiotherapy for Pancreatic Cancer, Hong Kong Journal of Radiology. 2017, 20(4): 303-311. |
| Chiang C.L., Lee W.Y., Yeung C.S.Y., Xu Z.Y., Lee F.A.S. and Chen Z.J., 圖像引導近距离放療（IGBT）在直腸癌根治性治療中的應用 — 單中心初步結果, CSTRO (9-Nov-2017), Beijing, China. 2017. |
| Chiang C.L., 直腸癌單純放療. 直腸癌放療專題學術講座, The University of Hong Kong Shenzhen Hospital, 28 July 2017, Shenzhen, China. 2017. |
| Ho C.H.M., Chiang C.L., Lee F.A.S., Choi C.W., Chan J.C.H., Yeung C.S.Y., Huang J.J., Chan M.K.H., Blanck O. and Wong F.C.S., Comparison of platelet-albumin-bilirubin (PALBI), albumin-bilirubin (ALBI), and child-pugh (CP) score for predicting of survival in advanced hcc patients receiving radiotherapy (RT), Oncotarget. 2018, 9. |
| Ho H.M., Chiang C.L., Lee A.S., Chan C.H., Yeung Y.S., Choi K.K., Wong C.S.F. and Tung Y., Albumin-Bilirubin (ALBI) versus Child-Pugh (CP) Score as a predictor of survival after Stereotactic Body Radiotherapy (SBRT) in Hepatocellular Carcinoma (HCC), ASTRO’s 59th Annual meeting, 25 September 2017, San Diego, United States. 2017. |
| Lam K.O., Shek W.H., Yang L., So T.H., Chiang C.L., Lam T.C., Lee V.H.F., Chen Z.J. and Lee W.M.A., BRAF-mutated metastatic colorectal cancer: Is intensive therapy and metastasectomy really necessary, The 13th Pan-Pearl-River Area Congress of Radiation Oncology, Wuhan, China. 2018. |
| Lee S.F., Chiang C.L., Lee F.A.S., Wong Y.W., Poon C.M.M., Wong C.S.F. and Tung S.Y., Outcome of neoadjuvant chemoradiation in MRI staged locally advanced rectal cancer: Retrospective analysis of 123 Chinese patients, Journal of the Formosan Medical Association. 2017. |
| Yang L., Xu Z.Y., Li J.S., Chen Z.J., Lee V.H.F., Lam K.O., Lam T.C., Chiang C.L., Chang T.Y.A., Huse V., Kwong D.L.W. and Lee W.M.A., The feasibility and short-term efficacy of induction chemotherapy with cisplatin and capecitabine followed by concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma, The 25th Annual Scientific Meeting, Hong Kong College of Radiologists, Hong Kong. 2017. |
| Yeung S.Y., Chiang C.L., Lee A.S., Ho H.M. and Tung Y., 8Gy Single Fraction (8Gy/1Fr) Palliative Radiotherapy (RT) For Hepatocellular Carcinoma (HCC): Safety And Efficacy, 8th Asia-Pacific Primary Liver Cancer Expert Meeting, 15 July 2017, Singapore. 2017. |
| Researcher : Choi CW |
| List of Research Outputs |
| Chiang C.L., Choi C.W., Mui W.H. and So T.H., 261OCost-effectiveness analysis of additional abiraterone for hormone-sensitive metastatic prostatic cancer treated with androgen deprivation therapy (ADT), Annals of Oncology. 2017, 28: 80. |
| Choi C.W., Sampling, HKCR Training Course in Clinical Oncology. 2017. |
| Choi C.W., Statistical tests and Significance I, HKCR Training Course in Clinical Oncology. 2017. |
| Choi C.W., Summarizing and Presentation of Data, HKCR Training Course in Clinical Oncology. 2017. |
| Ho C.H.M., Chiang C.L., Lee F.A.S., Choi C.W., Chan J.C.H., Yeung C.S.Y., Huang J.J., Chan M.K.H., Blanck O. and Wong F.C.S., Comparison of platelet-albumin-bilirubin (PALBI), albumin-bilirubin (ALBI), and child-pugh (CP) score for predicting of survival in advanced hcc patients receiving radiotherapy (RT), Oncotarget. 2018, 9. |
| Kwan K.Y.H., Lam T.C., Choi C.W., Koh H.Y. and Cheung K.M.C., Prediction of survival in patients with symptomatic spinal metastases: Comparison between the Tokuhashi score and expert oncologists, Surgical Oncology. 2018, 27: 7-10. |
| Lam P.L., Lam T.C., Choi C.W., Lee W.M.A., Yuen K.K. and Leung T.W., The impact of palliative care training for oncologists and integrative palliative service in a public-funded hospital cluster—a retrospective cohort study, Supportive Care in Cancer. 2017. |
| Lam T.C., Chan S.K. and Choi C.W., Mitotic count and male gender are predictors of radiological recurrence after surgical excision of meningioma, The 14th Meeting of the Asian Society for Neuro-Oncology (ASNO 2017). 2017. |
| Lee W.M.A., Tung S.Y., Ng W.T., Ngan K.C., Lee V.H.F., Choi C.W., Chan L., Lu T.X., Siu L.L., Tan T.W.K., Ng A.W.Y., Yiu H.H.Y., Leung T.W., O'Sullivan B., Tan E.H. and Chappell R.J., 10-Year Outcome on the Efficacy and Late Toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials), International Journal of Radiation Oncology, Biology, Physics. 2017, 99(2): S46-S46. |
| Ng W.T., Tung S.Y., Lee V.H.F., Ngan K.C.R., Choi C.W., Chan L.L.K., Leung T.W., Siu L.L., Lu T.X., Tan T., Tan E.H., Sze C.K.H., Ng A.W.Y., Yiu H.H.Y., O'Sullivan B., Chappell R. and Lee W.M.A., Concurrent-Adjuvant Chemoradiation Therapy for Stage III-IVB Nasopharyngeal Carcinoma—Exploration for Achieving Optimal 10-Year Therapeutic Ratio, International Journal of Radiation Oncology*Biology*Physics. 2018, 101: 1078-1086. |
| Researcher : Choi SSA |
| List of Research Outputs |
| Dai W., Ko J.M.Y., Choi S.S.A., Yu Z., NING L., Zheng H., Gopalan V., Chan K.T., Lee N.P.Y., Chan K.W., Law S.Y.K., Lam A.K.Y. and Lung M.L., Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma, Journal of Pathology. 2017, 242(4): 500-510. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Researcher : Chua DTT |
| Project Title: | 2000 Annual Meeting of the American Society for Therapeutic Radiology and Oncology Patterns of Failure after Induction Chemotherapy and Radiotherapy for Loco-Regionally Advanced Nasopharyngeal Carcinoma: The Queen Mary Hospital Experience |
| Investigator(s): | Chua DTT |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2000 |
| Project Title: | 2001 Annual Scientific Meeting of the American Society for Therapeutic Radiology and Oncology Control of Regional Metastasis after Induction Chemotherapy and Radiotherapy for Nasopharyngeal Carcinoma |
| Investigator(s): | Chua DTT |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2001 |
| Project Title: | The Radiological Society of North America 89th Scientific Assembly and Annual Meeting Prognostic Value of Tumor Volume in Early Stage Nasopharyngeal Carcinoma Treated by Radiotherapy |
| Investigator(s): | Chua DTT |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2003 |
| Project Title: | 46th Annual Meeting of the American Society for Therapeutic Radiology and Oncology Prognostic Impact of Hemoglobin Level on Treatment Outcome in Patients with Nasopharyngeal Carcinoma Treated with Sequential Chemoradiotherapy or Radiotherapy Alone |
| Investigator(s): | Chua DTT |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2004 |
| Researcher : DENG M |
| List of Research Outputs |
| DENG M., Cheung A.K.L., Dai W. and Lung M.L., Functional and molecular analysis of the loss-of-function somatic mutations in two NF-κB pathway inhibitors: NFKBIA and CYLD in nasopharyngeal carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Researcher : Dai W |
| Project Title: | Establishment of Gene Panel for Predicting Platinum-based Chemoresistance in Cancers |
| Investigator(s): | Dai W, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 03/2017 |
| Completion Date: | 08/2018 |
| Project Title: | Elucidation of a Critical Genetic Susceptibility Region Mapping to Chromosome 3p21.3 in Nasopharyngeal Carcinoma |
| Investigator(s): | Dai W, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals |
| Start Date: | 07/2017 |
| Completion Date: | 11/2017 |
| Project Title: | AACR Annual Meeting; Elucidation of genetic susceptibility in nasopharyngeal carcinoma (NPC) by next-generation sequencing |
| Investigator(s): | Dai W |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 04/2018 |
| Completion Date: | 04/2018 |
| List of Research Outputs |
| CHAI W.Y., Cheung A.K.L., Dai W., Ko J.M.Y., Lee N.P.Y., Chan K.T., Law S.Y.K. and Lung M.L., Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma, Cancer Biomarkers. 2018, 21: 583-590. |
| DENG M., Cheung A.K.L., Dai W. and Lung M.L., Functional and molecular analysis of the loss-of-function somatic mutations in two NF-κB pathway inhibitors: NFKBIA and CYLD in nasopharyngeal carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Dai W., Ko J.M.Y., Ng H.Y., Zheng H. and Lung M.L., Elucidation of Genetic Susceptibility in Nasopharyngeal Carcinoma by Next Generation Sequencing., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Dai W., Ko J.M.Y., Choi S.S.A., Yu Z., NING L., Zheng H., Gopalan V., Chan K.T., Lee N.P.Y., Chan K.W., Law S.Y.K., Lam A.K.Y. and Lung M.L., Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma, Journal of Pathology. 2017, 242(4): 500-510. |
| GUO C., Ko J.M.Y., Dai W., Law S.Y.K., Lo A. and Lung M.L., Genomic characterization of mutation hotspots related to chemotherapy responses in esophageal squamous cell carcinoma with archived formalin-fixed paraffin-embedded tissues., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members Resulting in Cisplatin Resistance in Nasopharyngeal Carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members in Nasopharyngeal Carcinoma., The 76th Annual Meeting of the Japanese Cancer Association, Tokyo, Japan. Sept 28-30, 2017.. 2017. |
| Researcher : FANG S |
| List of Research Outputs |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Researcher : GUO C |
| List of Research Outputs |
| GUO C., Ko J.M.Y., Dai W., Law S.Y.K., Lo A. and Lung M.L., Genomic characterization of mutation hotspots related to chemotherapy responses in esophageal squamous cell carcinoma with archived formalin-fixed paraffin-embedded tissues., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Researcher : Guan X |
| Project Title: | 49th Annual Meeting of the American Society of Human Genetics The Association of Chromosome 8p Deletion and Tumor Metastasis in Human Hepatocellular Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/1999 |
| Project Title: | 51st Annual Meeting of the American Society of Human Genetics Loss of Tyrosine Aminotransferase may Contribute to the Development of Hepatocellular Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2001 |
| Project Title: | Evaluation of an Oxygen Therapeutic (IKOR-2084) in the Enhancement of Chemotherapy and Radiotherapy in Rodent Cancer Models |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2009 |
| Project Title: | Evaluation of an Oxygen Therapeutic (IKOR-2084) in the Enhancement of Chemotherapy and Radiotherapy in Rodent Cancer Models |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2009 |
| Project Title: | Outstanding Researcher Award 2011-12 |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Outstanding Researcher Award |
| Start Date: | 01/2013 |
| Project Title: | Cancer |
| Investigator(s): | Guan X, Chan CLW, Tsao GSW |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2013 |
| Project Title: | Exploring the Mechanism for Cancer Associated Fibroblasts Recruitment and the Potential Therapeutic Value in Esophageal Squamous Cell Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | Investigation of effects and molecular mechanisms of FGFR2-positive cancer-associate fibroblasts on tumor microenvironment in esophageal squamous cell carcinoma |
| Investigator(s): | Guan X, Chen Z, Ma SKY |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 04/2015 |
| Project Title: | Establishing an intracellular targeting antibody platform for cancer treatment |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2015 |
| Project Title: | Characterization of the suppressive effects of ANG3 on cancer growth, metastasis and angiogenesis in hepatocellular carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2016 |
| Project Title: | Outstanding Research Student Supervisor Award 2015-16 |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Outstanding Research Student Supervisor Award |
| Start Date: | 11/2016 |
| Project Title: | Characterization of the effect of Maelstrom in cancer stemness in hepatocellular carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2017 |
| Project Title: | Investigating the effect of Rho GTPases regulator ARHGAP15 on gastric cancer metastasis |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 03/2018 |
| List of Research Outputs |
| Bai H., Liao Y., Cai M., Ma N., Zhang Q., Chen J., Zhang J., Wang F., Wang C., Chen W., Jin X., Xu R., Guan X. and Xie D., EIF5A2 contributes to the maintenance of CD133(+) hepatocellular carcinoma cells via the c-Myc/microRNA-29b axis, Stem Cell. 2018, 36: 180-191. |
| CAO T., Xiang D., Liu B., Huang T., Tan B., Zeng C., Wang Z., Ming X., ZHANG L., Jin G., Li F., Wu J., Guan X., Lu D. and Fu L., FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma, Oncotarget. 2017, 8: 65957-65968. |
| CHAN H.L., Zhou L., Ng K.Y., Wong T.L., CHAI S., Lee T.K., Guan X., Ching Y.P., Lo C.M., Man K., Artegiani B., Clevers H., Yan H.H.N., Leung S.Y., Richard S., Huen M.S.Y. and Ma S.K.Y., PRMT6-dependent CRAF/ERK signaling regulates cancer stem cell plasticity in liver cancer., AACR 2017 Annual Meeting. 2017. |
| CHE N., Tong M., Ng K.Y., Huen M.S.Y., Guan X. and Ma S.K.Y., Functional and Mechanistic Characterization of PRMT6-Regulated Autophagy in Hepatocellular Carcinoma, 22nd Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, HKU. 2017. |
| Dai Y., Liu L., Zeng T., Liang J., Song Y., Chen K., Li Y., Chen L., Zhu Y., LI J., Li Y., Xie D., Yuan Y. and Guan X., Overexpression of MUC13, a poor prognostic predictor, promotes cell growth by activating Wnt signaling in hepatocellular carcinoma, American Journal of Pathology. 2018, 188: 378-391. |
| Guan X., Kam N.W., Ming X.Y., Zhang X. and Cao T.T., RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-κB Signaling and MMP1 Expression., In: Ming XY, Zhang X, Cao TT, Zhang LY, Qi JL, Kam NW, Tang XM, Cui YZ, Zhang BZ, Li Y, Qin YR, Guan XY, Theranostics. 2018. |
| JIANG C., LI L., Li J.C., Xie S.H., Cao S.M. and Guan X., Abstract 722: Circulating EBV microRNA BART2-5p helps to diagnose nasopharyngeal carcinoma < screen for high risk individuals precisely, AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 722-722. |
| Kam N.W., Guan X. and Kwong D.L.W., Abstract 3999: Cross talk between tumor cell derived HMGB1 and adaptive B cells in the tumor microenvironment of esophageal squamous cell carcinoma, AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 3999-3999. |
| LAU C.C., Ng K.Y., Wong T.L., Tong M., Lee T.K., Ming X., Law S.Y.K., Lee N.P.Y., Cheung A., Qin Y.R., Chan K.W., Ning W., Guan X. and Ma S.K.Y., FSTL1 promotes metastasis and chemoresistance in esophageal squamous cell carcinoma through NFκB-BMP signaling crosstalk, Cancer Research. 2017, 77(21): 5886-5899. |
| LUK T.C.S., Tong M., Ng K.Y., Yip K.Y.L., Guan X. and Ma S.K.Y., Role of REX1 Down-Regulation in Promoting Cancer Stemness Properties in Hepatocellular Carcinoma, 22nd Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, HKU. 2017. |
| Li B., Xu W., Han L., Chan K.T., Tsao G.S.W., Lee N.P.Y., Law S.Y.K., Xu L.Y., Li E.M., Chan K.W., Qin Y.R., Guan X., He Q.Y. and Cheung A., MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF, Oncogene. 2017, 36(28): 3986-4000. |
| Li L., Zeng T., Zhang B., Li Y., Zhu Y. and Guan X., Overexpression of HN1L promotes cell malignant proliferation in non-small cell lung cancer, Cancer Biol Ther. 2017, 18: 904-915. |
| Luk S.T., Tong M., Ng K.Y., Guan X. and Ma S.K.Y., Identification of ZFP42/REX1 as a regulator of cancer stemness in CD133+ liver cancer stem cells by genome-wide DNA methylation analysis, AACR-Annual Meeting 2018, Chicago, IL, USA. 2018. |
| Luk S.T.C., Tong M., Ng K.Y., Yip K.Y.L., Guan X. and Ma S.K.Y., Abstract 4352: Identification of ZFP42/REX1 as a regulator of cancer stemness in CD133+ liver cancer stem cells by genome-wide DNA methylation analysis , AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 4352-4352. |
| MING X., Zhang X., CAO T., ZHANG L., QI J., TANG X., CUI Y., Zhang B., Li Y., Qin Y. and Guan X., RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression, Theranostics. 2018, 8: 185-198. |
| Ng K.Y., Chan L.H., Chai S., Tong M., Guan X., Lee N.P., Yuan Y.F., Xie D., Lee T.K., Carrier A., Dusetti N.J. and Ma S.K.Y., Abstract 4842: TP53INP1 negatively regulates ERK1/2 via p73-dependent DUSP10 expression to promote metastasis in hepatocellular carcinoma, AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 4842-4842. |
| Ng K.Y., Chan J.L.H., Chai S., Tong M., Guan X., Lee N.P.Y., Yuan Y.F., Xie D., Lee T.K., Dusetti N.J., Carrier A. and Ma S.K.Y., TP53INP1 down-regulation activates a p73-dependent DUSP10/ERK signaling pathway to promote metastasis of hepatocellular carcinoma, Cancer Research. 2017, 77(17): 4602-4612. |
| PENG F., Tang H., Liu P., Shen J., Guan X., Xie X., Gao J., Jia L., Chen J. and Peng C., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis., Scientific Reports . 2017, 7(1):9022. |
| Tong M., Wong T.L., Luk S.T.C., Che N., Wong K.Y., Fung T.M., Guan X., Lee N.P., Yuan Y.F., Lee T.K. and Ma S.K.Y., Abstract 1548: Down-regulation of 4-hydroxyphenylpyruvate dioxygenate (HPD) contributes to the pathogenesis of hepatocellular carcinoma (HCC) through ERK / BCL-2 signalling activation, AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 1548-1548. |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Zhang B., Zhang Z., Li L., Qin Y., Liu H., JIANG C., Zeng T., Li M., Xie D., Li Y., Guan X. and Zhu Y., TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling, Nature Communications. 2018, 9: 1423. |
| Zhang B.Z., Li M.Q., Huang P.Z., Guan X. and Zhu Y.H., Overexpression of ubiquitin specific peptidase 14 predicts unfavorable prognosis in esophageal squamous cell carcinoma, Thoracic Cancer. 2017, 8: 344-349. |
| Zhong Q., Liu Z., Lin Z., Hu Z., Yuan L., Liu Y., Zhou A., Xu L., Hu L., Wang Z., Guan X., Hao J., Lui V., Guo L., Mai H., Chen M., Han F., Xie Y., Grandis J. and Zhang X., The RARS-MAD1L1 fusion gene Induces cancer stem cell-like properties and therapeutic resistance in nasopharyngeal carcinoma, Clinic Cancer Research. 2018, 24: 659-673. |
| Zhou J., Siu H.C., Tong M., Chai S., Loong H.C., Sin S., Clevers H., Lo C.M., Man K., Guan X., Wongg D., Yan H.H., Leung S.Y. and Ma S.K.Y., Establishment of human primary hepatocellular carcinoma-derived organoid cultures for disease modeling and drug screening, International Society for Stem Cell Research- Annual Meeting, Melbourne, Australia. 2018. |
| Zhou L., Siu H.C., LOONG H.C., Tong M., Wong T.L., Chai S., XIAN Z., Guan X., Wong D.K.H., Man K., Lo C.M., Yan H.H.N., Leung S.Y., Clevers H. and Ma S.K.Y., Establishment Of Human Primary Hepatocellular Carcinoma-derived Organoid Cultures For Disease Modeling And Drug Screening, International Society For Stem Cell Research (ISSCR) 2018 Annal Meeting. 2018. |
| Zhou Y., Wang L., Ban X., Zeng T., Zhu Y., Li M., Guan X. and Li Y., DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma, Oncogene. 2018, 37: 1086-1094. |
| Researcher : Guan X. |
| Project Title: | 49th Annual Meeting of the American Society of Human Genetics The Association of Chromosome 8p Deletion and Tumor Metastasis in Human Hepatocellular Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/1999 |
| Project Title: | 51st Annual Meeting of the American Society of Human Genetics Loss of Tyrosine Aminotransferase may Contribute to the Development of Hepatocellular Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2001 |
| Project Title: | Evaluation of an Oxygen Therapeutic (IKOR-2084) in the Enhancement of Chemotherapy and Radiotherapy in Rodent Cancer Models |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2009 |
| Project Title: | Evaluation of an Oxygen Therapeutic (IKOR-2084) in the Enhancement of Chemotherapy and Radiotherapy in Rodent Cancer Models |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2009 |
| Project Title: | Outstanding Researcher Award 2011-12 |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Outstanding Researcher Award |
| Start Date: | 01/2013 |
| Project Title: | Cancer |
| Investigator(s): | Guan X, Chan CLW, Tsao GSW |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2013 |
| Project Title: | Exploring the Mechanism for Cancer Associated Fibroblasts Recruitment and the Potential Therapeutic Value in Esophageal Squamous Cell Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | Investigation of effects and molecular mechanisms of FGFR2-positive cancer-associate fibroblasts on tumor microenvironment in esophageal squamous cell carcinoma |
| Investigator(s): | Guan X, Chen Z, Ma SKY |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 04/2015 |
| Project Title: | Establishing an intracellular targeting antibody platform for cancer treatment |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2015 |
| Project Title: | Characterization of the suppressive effects of ANG3 on cancer growth, metastasis and angiogenesis in hepatocellular carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2016 |
| Project Title: | Outstanding Research Student Supervisor Award 2015-16 |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Outstanding Research Student Supervisor Award |
| Start Date: | 11/2016 |
| Project Title: | Characterization of the effect of Maelstrom in cancer stemness in hepatocellular carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2017 |
| Project Title: | Investigating the effect of Rho GTPases regulator ARHGAP15 on gastric cancer metastasis |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 03/2018 |
| List of Research Outputs |
| Researcher : Guan XY |
| Project Title: | 49th Annual Meeting of the American Society of Human Genetics The Association of Chromosome 8p Deletion and Tumor Metastasis in Human Hepatocellular Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/1999 |
| Project Title: | 51st Annual Meeting of the American Society of Human Genetics Loss of Tyrosine Aminotransferase may Contribute to the Development of Hepatocellular Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2001 |
| Project Title: | Evaluation of an Oxygen Therapeutic (IKOR-2084) in the Enhancement of Chemotherapy and Radiotherapy in Rodent Cancer Models |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2009 |
| Project Title: | Evaluation of an Oxygen Therapeutic (IKOR-2084) in the Enhancement of Chemotherapy and Radiotherapy in Rodent Cancer Models |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2009 |
| Project Title: | Outstanding Researcher Award 2011-12 |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Outstanding Researcher Award |
| Start Date: | 01/2013 |
| Project Title: | Cancer |
| Investigator(s): | Guan X, Chan CLW, Tsao GSW |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2013 |
| Project Title: | Exploring the Mechanism for Cancer Associated Fibroblasts Recruitment and the Potential Therapeutic Value in Esophageal Squamous Cell Carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | Investigation of effects and molecular mechanisms of FGFR2-positive cancer-associate fibroblasts on tumor microenvironment in esophageal squamous cell carcinoma |
| Investigator(s): | Guan X, Chen Z, Ma SKY |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 04/2015 |
| Project Title: | Establishing an intracellular targeting antibody platform for cancer treatment |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2015 |
| Project Title: | Characterization of the suppressive effects of ANG3 on cancer growth, metastasis and angiogenesis in hepatocellular carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2016 |
| Project Title: | Outstanding Research Student Supervisor Award 2015-16 |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Outstanding Research Student Supervisor Award |
| Start Date: | 11/2016 |
| Project Title: | Characterization of the effect of Maelstrom in cancer stemness in hepatocellular carcinoma |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2017 |
| Project Title: | Investigating the effect of Rho GTPases regulator ARHGAP15 on gastric cancer metastasis |
| Investigator(s): | Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 03/2018 |
| List of Research Outputs |
| Researcher : Ho PYP |
| List of Research Outputs |
| Chan M.F.T., Lam Q.Y.N., Lee V.H.F., Ho P.Y.P., Sze C.K.H., Siu W.K.S., Kwong W.K.P. and Leung T.W., Using the Roach Formula to Stratify Patients with Localised Prostate Cancer Treated with Intensity-modulated Radiotherapy, Hong Kong Journal of Radiology. 2017, 103-109. |
| Researcher : JIANG C |
| List of Research Outputs |
| JIANG C., LI L., Li J.C., Xie S.H., Cao S.M. and Guan X., Abstract 722: Circulating EBV microRNA BART2-5p helps to diagnose nasopharyngeal carcinoma < screen for high risk individuals precisely, AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 722-722. |
| Zhang B., Zhang Z., Li L., Qin Y., Liu H., JIANG C., Zeng T., Li M., Xie D., Li Y., Guan X. and Zhu Y., TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling, Nature Communications. 2018, 9: 1423. |
| Researcher : JIANG L |
| List of Research Outputs |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Researcher : Kam NW |
| List of Research Outputs |
| Guan X., Kam N.W., Ming X.Y., Zhang X. and Cao T.T., RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-κB Signaling and MMP1 Expression., In: Ming XY, Zhang X, Cao TT, Zhang LY, Qi JL, Kam NW, Tang XM, Cui YZ, Zhang BZ, Li Y, Qin YR, Guan XY, Theranostics. 2018. |
| Kam N.W., Guan X. and Kwong D.L.W., Abstract 3999: Cross talk between tumor cell derived HMGB1 and adaptive B cells in the tumor microenvironment of esophageal squamous cell carcinoma, AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 3999-3999. |
| Kam N.W. and WANG Y., An inflammation-related nomogram for predicting the survival of patients with non-small cell lung cancer after pulmonary lobectomy., In: Wang Y, Qu X, Kam NW, Wang K, Shen H, Liu Q, Du J., BMC Cancer. 2018. |
| Kam N.W., Radiation Protection Course, 2018. |
| Kam N.W., University of Hong Kong/China Medical Board Grant 2016/2017, University of Hong Kong/China Medical Board Grant 2016/2017. 2018. |
| Researcher : Ko JMY |
| Project Title: | The clinical relevance of telomere attrition and NPC genetic susceptibility |
| Investigator(s): | Ko JMY, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2015 |
| Project Title: | Validation and functional characterization of candidate genetic susceptibility loci and the inherited risk for familial esophageal squamous cell carcinoma (ESCC) |
| Investigator(s): | Ko JMY, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 10/2015 |
| Completion Date: | 10/2017 |
| Project Title: | Genomic and functional study of rare deleterious germline mutations in RAD50 associated with familial risk for esophageal carcinoma |
| Investigator(s): | Ko JMY, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | 3rd ACTC Advances in Circulating Tumour Cells : Liquid Biopsy in Clinical Practice; SERIAL MONITORING PD-L1 EXPRESSION IN CTCS OF ESOPHAGEAL CARCINOMA PATIENTS |
| Investigator(s): | Ko JMY |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2017 |
| Completion Date: | 10/2017 |
| Project Title: | Genomic and functional study of rare deleterious germline mutations in candidate genes associated with familial risk for esophageal carcinoma |
| Investigator(s): | Ko JMY, Huen MSY, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2018 |
| List of Research Outputs |
| CHAI W.Y., Cheung A.K.L., Dai W., Ko J.M.Y., Lee N.P.Y., Chan K.T., Law S.Y.K. and Lung M.L., Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma, Cancer Biomarkers. 2018, 21: 583-590. |
| Dai W., Ko J.M.Y., Ng H.Y., Zheng H. and Lung M.L., Elucidation of Genetic Susceptibility in Nasopharyngeal Carcinoma by Next Generation Sequencing., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Dai W., Ko J.M.Y., Choi S.S.A., Yu Z., NING L., Zheng H., Gopalan V., Chan K.T., Lee N.P.Y., Chan K.W., Law S.Y.K., Lam A.K.Y. and Lung M.L., Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma, Journal of Pathology. 2017, 242(4): 500-510. |
| GUO C., Ko J.M.Y., Dai W., Law S.Y.K., Lo A. and Lung M.L., Genomic characterization of mutation hotspots related to chemotherapy responses in esophageal squamous cell carcinoma with archived formalin-fixed paraffin-embedded tissues., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Vardhanabhuti V., Khong P.L., Ngan K.C.R., Ng W.T., Kwong D.L.W., Lee V.H.F., Lam K.O. and Lung M.L., Clinical usefulness of cmbined CTC enumeration, EBV DNA, and PET imaging for metastatic nasopharyngeal carcinoma., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Ko J.M.Y., Ng H.Y., Lam K.O. and Lung M.L., PD-L1 expression in CCs of esophageal carcinoma patients., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| LAM S.Y., NING L., Lung M.L. and Ko J.M.Y., Functional characterization of RAD50 germline deleterious variants identified from deep targetd sequencing study of familial esophageal squamous cell carcinoma., HKU Research Postgraduate Symposium. December 6, 2017.. 2017. |
| LAM S.Y., NING L., Ng H.Y., Lung M.L. and Ko J.M.Y., Functional characterization of Rad50 germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| LEI C., Yu Z., NING L., Ko J.M.Y., Wang L.D. and Lung M.L., Functional characterization of FANCD2 in esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| NING L., Ko J.M.Y., LEI C., Wang L.D. and Lung M.L., Investigating the germline deleterious rare variants for genetic susceptibility of esophagus squamous cell carcinoma by target sequencing., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| NING L., Ko J.M.Y. and Lung M.L., Targeted gene sequencing studies of CDKN2B-AS1 in nasopharyngeal carcinoma genetic susceptibility., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Researcher : Kwok CTT |
| List of Research Outputs |
| LEONG M.L., Cheung A.K.L., Kwok C.T.T. and Lung M.L., Functional Characterization of a candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Researcher : Kwong DLW |
| Project Title: | Knowledge and Technology Transfer through Advanced Training in Clinical Immunotherapy for Nasopharyngeal Carcinoma and other Virus Associated Malignancies |
| Investigator(s): | Kwong DLW, Nicholls JM |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Zeshan (HK) Foundation |
| Start Date: | 01/2016 |
| Project Title: | Cross-talk between tumor-cell derived HMGB-1 and adaptive B cells in the tumor microenvironment of Esophageal squamous cell carcinoma |
| Investigator(s): | Kwong DLW, Guan X |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals |
| Start Date: | 07/2017 |
| Completion Date: | 11/2017 |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| Chan W.L., Yuen K.K., Siu S.W.K., Lam K.O. and Kwong D.L.W., Third-line systemic treatment versus best supportive care for advanced/metastatic gastric cancer: A systematic review and meta-analysis, Critical Reviews in Oncology/Hematology. 2017, 116: 68-81. |
| Chen F., Co M., Jin H., Zhang A., Chen W., Liu F., Li Y., Lee V.H.F., Lam T.C., Chen Z., Huse V., Lam K.O., Lee W.M.A. and Kwong D.L.W., Implementation of neoadjuvant chemotherapy for breast cancer in HKUSZH: A real-world setting with Multiple Disciplinary Team, Global Breast Cancer Conference, Incheon, Korea. 2018. |
| Du R., Khong P.L., Yuan H., Kwong D.L.W., Lee V.H.F. and Vardhanabhuti V., Shape-based and quantitative MRI radiomic features in the assessment of non-metastatic nasopharyngeal carcinoma, European Conference of Radiology 2018. |
| Kam N.W., Guan X. and Kwong D.L.W., Abstract 3999: Cross talk between tumor cell derived HMGB1 and adaptive B cells in the tumor microenvironment of esophageal squamous cell carcinoma, AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 3999-3999. |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Vardhanabhuti V., Khong P.L., Ngan K.C.R., Ng W.T., Kwong D.L.W., Lee V.H.F., Lam K.O. and Lung M.L., Clinical usefulness of cmbined CTC enumeration, EBV DNA, and PET imaging for metastatic nasopharyngeal carcinoma., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Kwong D.L.W. and Tsang R.K.Y., Chapter 8. Nasopharyngeal Carcinoma, In: John Watkinson and Ray Clarke, Scott-Brown’s Otorhinolaryngology and Head and Neck Surgery Eight Edition. 2018. |
| Kwong D.L.W., Local and systemic treatment for recurrent head and neck cancer, Head & Neck Course 2018: Management of Recurrent Head and Neck Tumors, 7 June 2018. 2018. |
| Kwong D.L.W., Radiation Oncology & Total Body Irradiation (TBI) in paediatric oncology patients, Post-Registration Certificate Course in Paediatric Oncology Nursing 2017/2018, 10 January 2018. 2018. |
| Kwong D.L.W., Radiotherapy and Chemotherapy for Head and Neck Cancers, The 24th Certificate Course in ENT Diseases for Nurses, 22 February 2018. 2018. |
| Kwong D.L.W. and Lam K.O., Radiotherapy for Esophageal Adenocarcinoma, 2018, 7-17. |
| Lam K.O. and Kwong D.L.W., Chemotherapy for Esophageal Adenocarcinoma, 2018, 19-34. |
| Lam K.O., Law B., Chan W., Wong Y.H.I., Chiu W.H.K., So T.H., Chan S., Lee V.H.F., Chu K.M., Kwong D.L.W. and Law S.Y.K., P-066Feasibility study of intraperitoneal docetaxel combined with intravenous cisplatin and oral S-1 for gastric cancer patients with peritoneal carcinomatosis, Annals of Oncology. 2018, 29. |
| Lam K.O. and Kwong D.L.W., Target Therapy for Esophageal Adenocarcinoma, 2018, 51-65. |
| Lau K.S., Lam K.O., Chan W.L.W., Lee V.H.F., Kwong D.L.W. and Leung T.W., S-1 Versus S-1 Plus Cisplatin as First-line Treatment for Metastatic Gastric Cancer, Hong Kong Journal of Radiology. 2017, 318-322. |
| Lee V.H.F., Chan S.Y., Tong C.C., Lam K.O., Kwong D.L.W., Leung T.W. and Lee W.M.A., New hope for advanced nasopharyngeal cancer—an Epstein-Barr virus-driven endemic malignancy?, Translational Cancer Research. 2018, 7: S53-S57. |
| Lee W.M.A., Ng W.T., Pan J.J., Poh S.S., Ahn Y.C., AlHussain H., Corry J., Grau C., Grégoire V., Harrington K.J., Hu C.S., Kwong D.L.W., Langendijk J.A., Le Q.T., Lee N.Y., Lin J.C., Lu T.X., Mendenhall W.M., O'Sullivan B., Ozyar E., Peters L.J., Rosenthal D.I., Soong Y.L., Tao Y.G., Yom S.S. and Wee J.T., International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma, Radiotherapy and Oncology. 2017. |
| Li W.H.C., Lam T.H., Wong C.N., Fong D.Y.T., Kwong D.L.W., Tung S.Y., Ng C.S.M. and Sarna L., Helping Cancer Patients Quit Smoking Using Brief Risk Communication and Motivational Counseling: A Randomized Controlled Trial (poster and abstract), 7th Hong Kong International Nursing Forum, December 18-19, 2017, Hong Kong. 2017. |
| MAI Z., Lin J., Chiang S.C., Ngan K.C.R., Kwong D.L.W., Ng W.T., Ng A.W.Y., Yuen K.T., Ip D.K.M., Chan Y.H., Lee W.M.A., Ho D.S.Y., Lung M.L. and Lam T.H., Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study, Scientific Reports. 2018, 8: 7052. |
| Ng W.T., Ngan K.C., Kwong D.L.W., Tung S.Y., Yuen K.T., Kam M.K.M., Sze C.K.H., Yiu H.H.Y., Chan L.L.K., Lung M.L. and Lee W.M.A., Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma, International Journal of Radiation Oncology*Biology*Physics. 2018, 100: 630-638. |
| Tsang J.S., Tong K.H.D., Lam K.O., Law T.T., Wong Y.H.I., Chan K.K.D., Chan S.Y., Kwong D.L.W. and Law S.Y.K., Appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, Diseases of the Esophagus. 2017, 30(9): 1-8. |
| Wu V.W.C., Ying M.T.C. and Kwong D.L.W., A study on the post-radiotherapy changes of temporomandibular joint in nasopharyngeal carcinoma patients, The British Journal of Radiology. 2017, 90: 20170375. |
| YUAN H., Ai Q.Y., Kwong D.L.W., Fong D.Y.T., King A.D., Vardhanabhuti V., Lee V.H.F. and Khong P.L., Cervical nodal volume for prognostication and risk stratification of patients with nasopharyngeal carcinoma, and implications on the TNM-staging system, Scientific Reports. 2017, 7 (1): 10387. |
| Yang L., Xu Z.Y., Li J.S., Chen Z.J., Lee V.H.F., Lam K.O., Lam T.C., Chiang C.L., Chang T.Y.A., Huse V., Kwong D.L.W. and Lee W.M.A., The feasibility and short-term efficacy of induction chemotherapy with cisplatin and capecitabine followed by concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma, The 25th Annual Scientific Meeting, Hong Kong College of Radiologists, Hong Kong. 2017. |
| Yue P.Y., Ha W.Y., Lau C.C., Cheung F.M.F., Lee W.M.A., Ng W.T., Ngan K.C.R., Yau C.C., Kwong D.L.W., Lung H.L., Mak N.K., Lung M.L. and Wong R.N.S., MicroRNA profiling study reveals miR-150 in association with metastasis in nasopharyngeal carcinoma, Scientific Reports. 2017, 7. |
| Researcher : Kwong WKP |
| List of Research Outputs |
| Chan M.F.T., Lam Q.Y.N., Lee V.H.F., Ho P.Y.P., Sze C.K.H., Siu W.K.S., Kwong W.K.P. and Leung T.W., Using the Roach Formula to Stratify Patients with Localised Prostate Cancer Treated with Intensity-modulated Radiotherapy, Hong Kong Journal of Radiology. 2017, 103-109. |
| Researcher : LAM SY |
| List of Research Outputs |
| LAM S.Y., NING L., Lung M.L. and Ko J.M.Y., Functional characterization of RAD50 germline deleterious variants identified from deep targetd sequencing study of familial esophageal squamous cell carcinoma., HKU Research Postgraduate Symposium. December 6, 2017.. 2017. |
| LAM S.Y., NING L., Ng H.Y., Lung M.L. and Ko J.M.Y., Functional characterization of Rad50 germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Researcher : LEI C |
| List of Research Outputs |
| LEI C., Yu Z., NING L., Ko J.M.Y., Wang L.D. and Lung M.L., Functional characterization of FANCD2 in esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| NING L., Ko J.M.Y., LEI C., Wang L.D. and Lung M.L., Investigating the germline deleterious rare variants for genetic susceptibility of esophagus squamous cell carcinoma by target sequencing., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Researcher : LEONG ML |
| List of Research Outputs |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members Resulting in Cisplatin Resistance in Nasopharyngeal Carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members in Nasopharyngeal Carcinoma., The 76th Annual Meeting of the Japanese Cancer Association, Tokyo, Japan. Sept 28-30, 2017.. 2017. |
| LEONG M.L., Cheung A.K.L., Kwok C.T.T. and Lung M.L., Functional Characterization of a candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Researcher : LI J |
| List of Research Outputs |
| Dai Y., Liu L., Zeng T., Liang J., Song Y., Chen K., Li Y., Chen L., Zhu Y., LI J., Li Y., Xie D., Yuan Y. and Guan X., Overexpression of MUC13, a poor prognostic predictor, promotes cell growth by activating Wnt signaling in hepatocellular carcinoma, American Journal of Pathology. 2018, 188: 378-391. |
| Researcher : LI Y |
| List of Research Outputs |
| Dai Y., Liu L., Zeng T., Liang J., Song Y., Chen K., Li Y., Chen L., Zhu Y., LI J., Li Y., Xie D., Yuan Y. and Guan X., Overexpression of MUC13, a poor prognostic predictor, promotes cell growth by activating Wnt signaling in hepatocellular carcinoma, American Journal of Pathology. 2018, 188: 378-391. |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Researcher : LIU M |
| List of Research Outputs |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Researcher : Lam KO |
| Project Title: | Genomic profiling of circulating tumor cells in patients undergoing liver resection for metastatic colorectal cancer |
| Investigator(s): | Lam KO, Lung ML, Ko JMY, Chan ACY, Lee VHF, Choi CW |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2017 |
| Completion Date: | 04/2018 |
| Project Title: | Optimizing the selection of patients with metastatic colorectal cancer for liver resection – An immuno-clinical scoring system incorporating circulating tumor cell enumeration and clinical factors. |
| Investigator(s): | Lam KO, Lung ML, Ko JMY, Chan ACY, Lee VHF |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2017 |
| List of Research Outputs |
| AN H., Chiu W.H.K., Lam K.O. and Vardhanabhuti V., Clinical Outcomes and Progression Pattern of Patients with Complete Metabolic Response by 18F-FDG PET-CT in Patients with Metastatic Colorectal Carcinoma, RSNA. 2017. |
| An H., Chiu W.K., Lam K.O. and Vardhanabhuti V., Clinical Outcomes and Progression Pattern of Patients with Complete Metabolic Response by 18F-FDG PET-CT in Patients with Metastatic Colorectal Carcinoma, The 103rd Scientific Assembly and Annual Meeting, RSNA 201. 2017. |
| Chan W.L., Yuen K.K., Siu S.W.K., Lam K.O. and Kwong D.L.W., Third-line systemic treatment versus best supportive care for advanced/metastatic gastric cancer: A systematic review and meta-analysis, Critical Reviews in Oncology/Hematology. 2017, 116: 68-81. |
| Chen F., Co M., Jin H., Zhang A., Chen W., Liu F., Li Y., Lee V.H.F., Lam T.C., Chen Z., Huse V., Lam K.O., Lee W.M.A. and Kwong D.L.W., Implementation of neoadjuvant chemotherapy for breast cancer in HKUSZH: A real-world setting with Multiple Disciplinary Team, Global Breast Cancer Conference, Incheon, Korea. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Vardhanabhuti V., Khong P.L., Ngan K.C.R., Ng W.T., Kwong D.L.W., Lee V.H.F., Lam K.O. and Lung M.L., Clinical usefulness of cmbined CTC enumeration, EBV DNA, and PET imaging for metastatic nasopharyngeal carcinoma., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Ko J.M.Y., Ng H.Y., Lam K.O. and Lung M.L., PD-L1 expression in CCs of esophageal carcinoma patients., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| Kwong D.L.W. and Lam K.O., Radiotherapy for Esophageal Adenocarcinoma, 2018, 7-17. |
| Lai V., Lee V.H.F., Lam K.O., Huang B., Chan Q. and Khong P.L., Intravoxel incoherent motion MR imaging in nasopharyngeal carcinoma: Comparison and correlation with dynamic contrast enhanced MR imaging, Oncotarget. 2017, 8(40): 68472-68482. |
| Lam K.O., Anti-Angiogenesis in mCRC: Aligning Global Perspective and Local Experience, The 25th Annual Scientific Meeting of Hong Kong College of Radiologists, Hong Kong. 2017. |
| Lam K.O., Shek W.H., Yang L., So T.H., Chiang C.L., Lam T.C., Lee V.H.F., Chen Z.J. and Lee W.M.A., BRAF-mutated metastatic colorectal cancer: Is intensive therapy and metastasectomy really necessary, The 13th Pan-Pearl-River Area Congress of Radiation Oncology, Wuhan, China. 2018. |
| Lam K.O., Biomarkers and Radiology, Metastatic Colorectal Cancer Medical Advisory Board: An Evolving Treatment Landscape, Singapore. 2017. |
| Lam K.O. and Kwong D.L.W., Chemotherapy for Esophageal Adenocarcinoma, 2018, 19-34. |
| Lam K.O., Editorial Board Member, In: Wiley, Asia-Pacific Journal of Clinical Oncology - Hong Kong Supplement. Wiley, 2018. |
| Lam K.O., Gastric Cancer Treatment Update, Hong Kong Pharmaceutical Care Foundation Gastric Cancer Talk, Hong Kong. 2017. |
| Lam K.O., Gastric Cancer in Hong Kong, Asia-Pacific Gastric Cancer Advisory Board Meeting, Kobe, Japan. 2017. |
| Lam K.O., Hindsight, Foresight and Insight, Best of ASCO 2017 Meeting, Bangkok, Thailand. 2017. |
| Lam K.O., Optimal Sequencing in Third Line mCRC to Extend Survival, Best of ASCO 2017 Meeting, Bangkok, Thailand. 2017. |
| Lam K.O., Law B., Chan W., Wong Y.H.I., Chiu W.H.K., So T.H., Chan S., Lee V.H.F., Chu K.M., Kwong D.L.W. and Law S.Y.K., P-066Feasibility study of intraperitoneal docetaxel combined with intravenous cisplatin and oral S-1 for gastric cancer patients with peritoneal carcinomatosis, Annals of Oncology. 2018, 29. |
| Lam K.O., Real Life experiences of regorafenib in refractory mCRC - Hong Kong Experience and Case Sharing, Scientific Symposium by Macao Oncology Association, Macau. 2017. |
| Lam K.O., Strategy for Gastric Cancer with Peritoneal Metastasis, Asian KOLs Meeting, Kobe, Japan. 2017. |
| Lam K.O. and Kwong D.L.W., Target Therapy for Esophageal Adenocarcinoma, 2018, 51-65. |
| Lam K.O., Lee K.C., Chiu W.Y.J., Lee V.H.F., Leung R.C.Y., Choy T.S. and Yau T.C.C., The Real World Use of Regorafenib for Metastatic Colorectal Cancer: Multicenter Analysis of Treatment Pattern and Outcomes in Hong Kong, Postgraduate Medical Journal. 2017, 395-400. |
| Lam K.O., 抗EGFR治疗在转移性结直肠癌中的应用: 合适的患者，合适的时机, 精准诊疗导向的肿瘤研究学术研讨会, 杭州, 中國. 2017. |
| Lau K.S., Lam K.O., Chan W.L.W., Lee V.H.F., Kwong D.L.W. and Leung T.W., S-1 Versus S-1 Plus Cisplatin as First-line Treatment for Metastatic Gastric Cancer, Hong Kong Journal of Radiology. 2017, 318-322. |
| Lee V.H.F., Chan S.Y., Tong C.C., Lam K.O., Kwong D.L.W., Leung T.W. and Lee W.M.A., New hope for advanced nasopharyngeal cancer—an Epstein-Barr virus-driven endemic malignancy?, Translational Cancer Research. 2018, 7: S53-S57. |
| So T.H., Lee V.H.F. and Lam K.O., Aflibercept-induced Nephrotic Syndrome, 阿普西柏誘發的腎病綜合症, Hong Kong Journal of Radiology. 2017. |
| Tsang J.S., Tong K.H.D., Lam K.O., Law T.T., Wong Y.H.I., Chan K.K.D., Chan S.Y., Kwong D.L.W. and Law S.Y.K., Appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, Diseases of the Esophagus. 2017, 30(9): 1-8. |
| Yang L., Xu Z.Y., Li J.S., Chen Z.J., Lee V.H.F., Lam K.O., Lam T.C., Chiang C.L., Chang T.Y.A., Huse V., Kwong D.L.W. and Lee W.M.A., The feasibility and short-term efficacy of induction chemotherapy with cisplatin and capecitabine followed by concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma, The 25th Annual Scientific Meeting, Hong Kong College of Radiologists, Hong Kong. 2017. |
| Zeng Z.C., Seong J., Yoon S.M., Cheng J.C.H., Lam K.O., Lee A.S., Law L.Y.A., Zhang J.Y. and Hu Y., Consensus on Stereotactic Body Radiation Therapy for Small-Sized Hepatocellular Carcinoma at the 7th Asia-Pacific Primary Liver Cancer Expert Meeting, Liver Cancer. 2017, 6: 264-274. |
| Researcher : Lam TC |
| Project Title: | A prospective cohort study on demoralization, quality of life and suicidal risk in advanced cancer patients |
| Investigator(s): | Lam TC, Lam WWT, Lee WMA, Kwong DLW, Lee VHF, Lam KO, So TH, Choi CW |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 02/2017 |
| Project Title: | Improving Access of MRI in Palliative Cancer Patients to Prevent Spinal Complications |
| Investigator(s): | Lam TC, Kwan KYH |
| Department: | Clinical Oncology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 04/2018 |
| List of Research Outputs |
| Chen F., Co M., Jin H., Zhang A., Chen W., Liu F., Li Y., Lee V.H.F., Lam T.C., Chen Z., Huse V., Lam K.O., Lee W.M.A. and Kwong D.L.W., Implementation of neoadjuvant chemotherapy for breast cancer in HKUSZH: A real-world setting with Multiple Disciplinary Team, Global Breast Cancer Conference, Incheon, Korea. 2018. |
| Kwan K.Y.H., Lam T.C., Choi C.W., Koh H.Y. and Cheung K.M.C., Prediction of survival in patients with symptomatic spinal metastases: Comparison between the Tokuhashi score and expert oncologists, Surgical Oncology. 2018, 27: 7-10. |
| Lam K.O., Shek W.H., Yang L., So T.H., Chiang C.L., Lam T.C., Lee V.H.F., Chen Z.J. and Lee W.M.A., BRAF-mutated metastatic colorectal cancer: Is intensive therapy and metastasectomy really necessary, The 13th Pan-Pearl-River Area Congress of Radiation Oncology, Wuhan, China. 2018. |
| Lam P.L., Lam T.C., Choi C.W., Lee W.M.A., Yuen K.K. and Leung T.W., The impact of palliative care training for oncologists and integrative palliative service in a public-funded hospital cluster—a retrospective cohort study, Supportive Care in Cancer. 2017. |
| Lam T.C., Sahgal A., Lo S. and Chang E., An update on radiation therapy for brain metastases, Chinese Clinical Oncology. 2017, 6: 35-35. |
| Lam T.C., Chan S.K. and Choi C.W., Mitotic count and male gender are predictors of radiological recurrence after surgical excision of meningioma, The 14th Meeting of the Asian Society for Neuro-Oncology (ASNO 2017). 2017. |
| Lam T.C., The Status of SBRT in Hong Kong, 25th Annual Scientific Meeting of Hong Kong College of Radiologists. 2017. |
| Lau H.P., Chow A.Y.M., Wong F.K.D., Chan J.S.M., Chan C.H.Y., Ho R.T.H., So T.H., Lam T.C., Lee V.H.F. and Lee W.M.A., Study Protocol of a Randomized Controlled Trial Comparing Integrative Body-Mind-Spirit Intervention and Cognitive Behavioural Therapy in Fostering Quality of Life of Patients with Lung Cancer and their Family Caregivers., Journal of Evidence-informed Social Work. 2018, 15(3): 258-276. |
| Mui W.H., Lam T.C., Wong F.C.S. and Sze W.K., Survival analysis of malignant epidural spinal cord compression after palliative radiotherapy using Tokuhashi scoring system and the impact of systemic therapy, Annals of Palliative Medicine. 2017, 6: S132-S139. |
| Shi D., Hertan L.M., Lam T.C., Skamene S., Chi J., Groff M. and Balboni T.A., Assessing the Utility of the Spinal Instability in Neoplasia Score to Predict Fracture after Conventional Radiation Therapy for Spinal Metastases, ASTRO 2017 Annual Meeting - American Society for Radiation Oncology. 2017. |
| Shi D., Chen Y.H., Lam T.C., Leonard D., Balboni T.A., Schoenfeld A., Skamene S., Cagney D., Chi J., Cho C., Harris M., Ferrone M.L. and Hertan L.M., Assessing the utility of a prognostication model to predict 1-year mortality in patients undergoing radiation therapy for spinal metastases, The Spine Journal. 2018, 18: 935-940. |
| Yang L., Xu Z.Y., Li J.S., Chen Z.J., Lee V.H.F., Lam K.O., Lam T.C., Chiang C.L., Chang T.Y.A., Huse V., Kwong D.L.W. and Lee W.M.A., The feasibility and short-term efficacy of induction chemotherapy with cisplatin and capecitabine followed by concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma, The 25th Annual Scientific Meeting, Hong Kong College of Radiologists, Hong Kong. 2017. |
| Researcher : Lau KS |
| List of Research Outputs |
| Lau K.S., Lam K.O., Chan W.L.W., Lee V.H.F., Kwong D.L.W. and Leung T.W., S-1 Versus S-1 Plus Cisplatin as First-line Treatment for Metastatic Gastric Cancer, Hong Kong Journal of Radiology. 2017, 318-322. |
| Researcher : Law LYA |
| List of Research Outputs |
| Zeng Z.C., Seong J., Yoon S.M., Cheng J.C.H., Lam K.O., Lee A.S., Law L.Y.A., Zhang J.Y. and Hu Y., Consensus on Stereotactic Body Radiation Therapy for Small-Sized Hepatocellular Carcinoma at the 7th Asia-Pacific Primary Liver Cancer Expert Meeting, Liver Cancer. 2017, 6: 264-274. |
| Researcher : Lee AWM |
| Project Title: | Prognostic and predictive biomarkers in loco-regionally advanced nasopharyngeal carcinoma treated with radiotherapy alone or in conjunction with chemotherapy: pooled analysis of data from the NPC-9901 and NPC-9902 trials |
| Investigator(s): | Lee WMA, Lam KO, Lee VHF, So TH, Kwong DLW, Guan X, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 04/2016 |
| Completion Date: | 04/2018 |
| Project Title: | Astro's 59th Annual Meeting; 10-Year Outcome on the Efficacy and Late toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials) |
| Investigator(s): | Lee WMA |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2017 |
| List of Research Outputs |
| Researcher : Lee VHF |
| Project Title: | Granulocyte-colony stimulating factor (G-CSF) support to prevent neutropenia and its complications for patients receiving palliative chemotherapy for their stage IV metastatic cancer |
| Investigator(s): | Lee VHF, Kwong DLW, Lam KO |
| Department: | Clinical Oncology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 01/2014 |
| Project Title: | Development of Cancer Registry of Human Papilloma Virus (HPV)-associated Oral and Oropharyngeal Cancers in Hong Kong and its Correlation with Survival Outcomes |
| Investigator(s): | Lee VHF, Kwong DLW, Lam KO, Sze CKH |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| Project Title: | ASTRO 56th Annual Meeting; Comparison of Post-treatment Plasma EBV DNA with Nasopharyngeal Biopsy in Patients After Radical (Chemo)Radiotherapy for Non-metastatic Nasopharyngeal Cancer |
| Investigator(s): | Lee VHF |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2014 |
| Project Title: | Magnetic resonance imaging (MRI) for monitoring treatment response in patients with inoperable hepatocellular carcinoma treated with transarterial chemoembolization (TACE) and/or radiotherapy |
| Investigator(s): | Lee VHF, Kwong DLW, Wong CS |
| Department: | Clinical Oncology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 01/2015 |
| Project Title: | FDG and 11C-acetate PET-CT scan to assess tumour response after stereotactic body radiation therapy as bridging therapy for patients with hepatocellular carcinoma awaiting liver transplantation |
| Investigator(s): | Lee VHF, Wong CLT, Vardhanabhuti V, Lam KO, Leung TW, Khong PL, Chan SC, Lo CM |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2016 |
| Project Title: | Role of individual dietary counselling on weight loss and change in quality of life in patients with nasopharyngeal carcinoma treated with intensity-modulated radiation therapy |
| Investigator(s): | Lee VHF, Kwong DLW, Lam KO, Sze CKH |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2016 |
| Project Title: | Efficient Algorithms and Hardware Accelerators for Tensor Decomposition and Their Applications to Multidimensional Data Analysis |
| Investigator(s): | Lee VHF |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2016 |
| Project Title: | Territory-wide evaluation of treatment outcomes of non-metastatic nasopharyngeal carcinoma treated with radical intensity-modulated radiation therapy in Hong Kong |
| Investigator(s): | Lee VHF, Choi CW, Lee WMA |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2018 |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| Chan M.F.T., Lam Q.Y.N., Lee V.H.F., Ho P.Y.P., Sze C.K.H., Siu W.K.S., Kwong W.K.P. and Leung T.W., Using the Roach Formula to Stratify Patients with Localised Prostate Cancer Treated with Intensity-modulated Radiotherapy, Hong Kong Journal of Radiology. 2017, 103-109. |
| Chan O.S.H., Lee V.H.F., Mok T.S.K., Mo F., Chang T.Y.A. and Yeung M.W.R., The Role of Radiotherapy in Epidermal Growth Factor Receptor Mutation-positive Patients with Oligoprogression: A Matched-cohort Analysis, Clinical Oncology. 2017, 29: 568-575. |
| Chen F., Co M., Jin H., Zhang A., Chen W., Liu F., Li Y., Lee V.H.F., Lam T.C., Chen Z., Huse V., Lam K.O., Lee W.M.A. and Kwong D.L.W., Implementation of neoadjuvant chemotherapy for breast cancer in HKUSZH: A real-world setting with Multiple Disciplinary Team, Global Breast Cancer Conference, Incheon, Korea. 2018. |
| Chen L.L., Zou B., Lee V.H.F. and Yan H., Analysis of the Relative Movements Between EGFR and Drug Inhibitors Based on Molecular Dynamics Simulation, Current Bioinformatics. 2018, 13: 299-309. |
| Cheung T.T., Kwok P.C., Chan S., Cheung C.C., Lee A.S., Lee V.H.F., Cheng H.C., Chia N.H., Chong C.C.N., Lai T.W., Law A.L.Y., Luk M.Y., Tong C.C. and Yau T.C.C., Hong Kong Consensus Statements for the Management of Unresectable Hepatocellular Carcinoma, Liver Cancer. 2018, 7: 40-54. |
| Chiang C.L., So T.H., Chen Z.J., Lee V.H.F. and Lee W.M.A., Pursuit of Excellence in the Management of Nasopharyngeal Carcinoma (NPC), International Journal of Head and Neck Science. 2017, 1(4): 199-211. |
| Chiang C.L., Yeung C.S.Y., Wong M.Y.P., Lee W.Y., Lee V.H.F., Lee F.A.S. and Wong F.C.S., Stereotactic Body Radiotherapy for Pancreatic Cancer, Hong Kong Journal of Radiology. 2017, 20(4): 303-311. |
| Du R., Mohammed Shah Alam ., Lee V.H.F. and Vardhanabhuti V., Association between multi-phasic MRI radiomic features and treatment response after stereotactic body radiation therapy, European Conference of Radiology 2018. |
| Du R., Khong P.L., Yuan H., Kwong D.L.W., Lee V.H.F. and Vardhanabhuti V., Shape-based and quantitative MRI radiomic features in the assessment of non-metastatic nasopharyngeal carcinoma, European Conference of Radiology 2018. |
| GAO X., XU H., Ho J.C.M., Xu F., Lee V.H.F., Tin P.C., Xiao Z., WANG S., Yam J.W.P. and Wong M.P., EGFR-mutant lung adenocarcinomas mutation profiles reveal ARID1A might be a novel tyrosine kinase resistance pathway, 111th Annual Meeting of the American Association for Cancer Research. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Vardhanabhuti V., Khong P.L., Ngan K.C.R., Ng W.T., Kwong D.L.W., Lee V.H.F., Lam K.O. and Lung M.L., Clinical usefulness of cmbined CTC enumeration, EBV DNA, and PET imaging for metastatic nasopharyngeal carcinoma., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Lai V., Lee V.H.F., Lam K.O., Huang B., Chan Q. and Khong P.L., Intravoxel incoherent motion MR imaging in nasopharyngeal carcinoma: Comparison and correlation with dynamic contrast enhanced MR imaging, Oncotarget. 2017, 8(40): 68472-68482. |
| Lam K.O., Shek W.H., Yang L., So T.H., Chiang C.L., Lam T.C., Lee V.H.F., Chen Z.J. and Lee W.M.A., BRAF-mutated metastatic colorectal cancer: Is intensive therapy and metastasectomy really necessary, The 13th Pan-Pearl-River Area Congress of Radiation Oncology, Wuhan, China. 2018. |
| Lam K.O., Law B., Chan W., Wong Y.H.I., Chiu W.H.K., So T.H., Chan S., Lee V.H.F., Chu K.M., Kwong D.L.W. and Law S.Y.K., P-066Feasibility study of intraperitoneal docetaxel combined with intravenous cisplatin and oral S-1 for gastric cancer patients with peritoneal carcinomatosis, Annals of Oncology. 2018, 29. |
| Lam K.O., Lee K.C., Chiu W.Y.J., Lee V.H.F., Leung R.C.Y., Choy T.S. and Yau T.C.C., The Real World Use of Regorafenib for Metastatic Colorectal Cancer: Multicenter Analysis of Treatment Pattern and Outcomes in Hong Kong, Postgraduate Medical Journal. 2017, 395-400. |
| Lau H.P., Chow A.Y.M., Wong F.K.D., Chan J.S.M., Chan C.H.Y., Ho R.T.H., So T.H., Lam T.C., Lee V.H.F. and Lee W.M.A., Study Protocol of a Randomized Controlled Trial Comparing Integrative Body-Mind-Spirit Intervention and Cognitive Behavioural Therapy in Fostering Quality of Life of Patients with Lung Cancer and their Family Caregivers., Journal of Evidence-informed Social Work. 2018, 15(3): 258-276. |
| Lau K.S., Lam K.O., Chan W.L.W., Lee V.H.F., Kwong D.L.W. and Leung T.W., S-1 Versus S-1 Plus Cisplatin as First-line Treatment for Metastatic Gastric Cancer, Hong Kong Journal of Radiology. 2017, 318-322. |
| Lee V.H.F., Chan S.Y., Tong C.C., Lam K.O., Kwong D.L.W., Leung T.W. and Lee W.M.A., New hope for advanced nasopharyngeal cancer—an Epstein-Barr virus-driven endemic malignancy?, Translational Cancer Research. 2018, 7: S53-S57. |
| Lee W.M.A., Tung S.Y., Ng W.T., Ngan K.C., Lee V.H.F., Choi C.W., Chan L., Lu T.X., Siu L.L., Tan T.W.K., Ng A.W.Y., Yiu H.H.Y., Leung T.W., O'Sullivan B., Tan E.H. and Chappell R.J., 10-Year Outcome on the Efficacy and Late Toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials), International Journal of Radiation Oncology, Biology, Physics. 2017, 99(2): S46-S46. |
| Ng W.T., Tung S.Y., Lee V.H.F., Ngan K.C.R., Choi C.W., Chan L.L.K., Leung T.W., Siu L.L., Lu T.X., Tan T., Tan E.H., Sze C.K.H., Ng A.W.Y., Yiu H.H.Y., O'Sullivan B., Chappell R. and Lee W.M.A., Concurrent-Adjuvant Chemoradiation Therapy for Stage III-IVB Nasopharyngeal Carcinoma—Exploration for Achieving Optimal 10-Year Therapeutic Ratio, International Journal of Radiation Oncology*Biology*Physics. 2018, 101: 1078-1086. |
| Ng W.T., Wong E.C.Y., Lee V.H.F., Chan Y.W. and Lee W.M.A., Head and neck cancer in Hong Kong, Japanese Journal of Clinical Oncology. 2018, 48(1): 13-21. |
| So T.H., Lee V.H.F. and Lam K.O., Aflibercept-induced Nephrotic Syndrome, 阿普西柏誘發的腎病綜合症, Hong Kong Journal of Radiology. 2017. |
| Wong C.L.T., Lee V.H.F., Law A.L.Y., Cui T.Y.S., Shing B.S.Y., Chok K.S.H., Cheung T.T., Chan A.C.Y., Dai W.C., Ng K.K.C., Leung T.W. and Lo C.M., Stereotactic body radiation therapy for hepatocellular carcinoma patients on waiting list for liver transplantation: an interim analysis. , 21st Asian Congress of Surgery. 2017. |
| Wong C.L.T., Lee V.H.F., Law A.H.Y., Cui T.Y.S., Shing B.S.Y., Chok K.S.H., Cheung T.T., Chan A.C.Y., Dai W.C. and Ng K.K.C., Stereotactic body radiation therapy for hepatocellular carcinoma patients on waiting list for liver transplantation: an interim analysis. Stereotactic body radiation therapy for hepatocellular carcinoma patients on waiting list for liver transplantation: an interim analysis. , 21st Asian Congress of Surgery. 2017. |
| Wu Y.L., Tu H., Feng J., Shi M., Zhao J., Wang Y., Chang J., Wang J., Cheng Y., Zhu J., Tan E.H., Li K., Zhang Y., Lee V.H.F., Yang C.T., Su W.C., Lam C.L.D., Srinivasa B.J., Rajappa S., Ho C.L., Lam K.C., Hu Y., Bondarde S.A., Liu X.Q., Fan J., Kuo D., Wang Y., Pang K. and Zhou C., A Phase IIIb open-label, single-arm study of afatinib in EGFR TKI-naïve patients with EGFRm+ NSCLC: An interim analysis., World Lung Cancer Conference, Yokohama, Japan, 2017. |
| YUAN H., Ai Q.Y., Kwong D.L.W., Fong D.Y.T., King A.D., Vardhanabhuti V., Lee V.H.F. and Khong P.L., Cervical nodal volume for prognostication and risk stratification of patients with nasopharyngeal carcinoma, and implications on the TNM-staging system, Scientific Reports. 2017, 7 (1): 10387. |
| Yang L., Xu Z.Y., Li J.S., Chen Z.J., Lee V.H.F., Lam K.O., Lam T.C., Chiang C.L., Chang T.Y.A., Huse V., Kwong D.L.W. and Lee W.M.A., The feasibility and short-term efficacy of induction chemotherapy with cisplatin and capecitabine followed by concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma, The 25th Annual Scientific Meeting, Hong Kong College of Radiologists, Hong Kong. 2017. |
| Zou B., Lee V.H.F., Chen L.J., Ma L.C., Wang D.D. and Yan H., Deciphering mechanisms of acquired T790M mutation after EGFR inhibitors for NSCLC by computational simulations, Scientific Reports. 2017, 7. |
| Zou B., Lee V.H.F. and Yan H., Prediction of sensitivity to gefitinib/erlotinib for EGFR mutations in NSCLC based on structural interaction fingerprints and multilinear principal component analysis, BMC Bioinformatics. 2018, 19. |
| Researcher : Lee WMA |
| Project Title: | Prognostic and predictive biomarkers in loco-regionally advanced nasopharyngeal carcinoma treated with radiotherapy alone or in conjunction with chemotherapy: pooled analysis of data from the NPC-9901 and NPC-9902 trials |
| Investigator(s): | Lee WMA, Lam KO, Lee VHF, So TH, Kwong DLW, Guan X, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 04/2016 |
| Completion Date: | 04/2018 |
| Project Title: | Astro's 59th Annual Meeting; 10-Year Outcome on the Efficacy and Late toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials) |
| Investigator(s): | Lee WMA |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2017 |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| Chen F., Co M., Jin H., Zhang A., Chen W., Liu F., Li Y., Lee V.H.F., Lam T.C., Chen Z., Huse V., Lam K.O., Lee W.M.A. and Kwong D.L.W., Implementation of neoadjuvant chemotherapy for breast cancer in HKUSZH: A real-world setting with Multiple Disciplinary Team, Global Breast Cancer Conference, Incheon, Korea. 2018. |
| Chiang C.L., So T.H., Chen Z.J., Lee V.H.F. and Lee W.M.A., Pursuit of Excellence in the Management of Nasopharyngeal Carcinoma (NPC), International Journal of Head and Neck Science. 2017, 1(4): 199-211. |
| Fernández-Alvarez V., López F., Suárez C., Strojan P., Eisbruch A., Silver C.E., Mendenhall W.M., Langendijk J.A., Rinaldo A., Lee W.M.A., Beitler J.J., Smee R., Alvarez J. and Ferlito A., Strahleninduzierte Läsionen der Karotisarterie, Strahlentherapie und Onkologie. 2018. |
| Grégoire V., Evans M., Le Q.T., Bourhis J., Budach V., Chen A., Eisbruch A., Feng M., Giralt J., Gupta T., Hamoir M., Helito J.K., Hu C., Hunter K., Johansen J., Kaanders J., Laskar S.G., Lee W.M.A., Maingon P., Mäkitie A., Micciche' F., Nicolai P., O'Sullivan B., Poitevin A., Porceddu S., Składowski K., Tribius S., Waldron J., Wee J., Yao M., Yom M., Zimmermann F. and Crau C., Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines, Radiotherapy and Oncology. 2017. |
| Kessel K.A., Lee W.M.A., Bentzen S.M., Vikram B., Nüsslin F. and Combs S.E., Editorial: Data Based Radiation Oncology—Design of Clinical Trials, Frontiers in Oncology. 2018, 8. |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Lam K.O., Shek W.H., Yang L., So T.H., Chiang C.L., Lam T.C., Lee V.H.F., Chen Z.J. and Lee W.M.A., BRAF-mutated metastatic colorectal cancer: Is intensive therapy and metastasectomy really necessary, The 13th Pan-Pearl-River Area Congress of Radiation Oncology, Wuhan, China. 2018. |
| Lam P.L., Lam T.C., Choi C.W., Lee W.M.A., Yuen K.K. and Leung T.W., The impact of palliative care training for oncologists and integrative palliative service in a public-funded hospital cluster—a retrospective cohort study, Supportive Care in Cancer. 2017. |
| Lau H.P., Chow A.Y.M., Wong F.K.D., Chan J.S.M., Chan C.H.Y., Ho R.T.H., So T.H., Lam T.C., Lee V.H.F. and Lee W.M.A., Study Protocol of a Randomized Controlled Trial Comparing Integrative Body-Mind-Spirit Intervention and Cognitive Behavioural Therapy in Fostering Quality of Life of Patients with Lung Cancer and their Family Caregivers., Journal of Evidence-informed Social Work. 2018, 15(3): 258-276. |
| Lee V.H.F., Chan S.Y., Tong C.C., Lam K.O., Kwong D.L.W., Leung T.W. and Lee W.M.A., New hope for advanced nasopharyngeal cancer—an Epstein-Barr virus-driven endemic malignancy?, Translational Cancer Research. 2018, 7: S53-S57. |
| Lee W.M.A., 10-Year Outcome on the Efficacy and Late Toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials), ASTRO 2017 Annual Meeting. 2017. |
| Lee W.M.A., Tung S.Y., Ng W.T., Ngan K.C., Lee V.H.F., Choi C.W., Chan L., Lu T.X., Siu L.L., Tan T.W.K., Ng A.W.Y., Yiu H.H.Y., Leung T.W., O'Sullivan B., Tan E.H. and Chappell R.J., 10-Year Outcome on the Efficacy and Late Toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials), International Journal of Radiation Oncology, Biology, Physics. 2017, 99(2): S46-S46. |
| Lee W.M.A., Advances in Radiotherapy and Fundamental Standardization of Planning for Nasopharyngeal Cancer, The First International Particle Therapy and Clinical Research Summit (IPTCRS), 27-28 March 2018, Wuxi, China. 2018. |
| Lee W.M.A., Ng W.T., Pan J.J., Poh S.S., Ahn Y.C., AlHussain H., Corry J., Grau C., Grégoire V., Harrington K.J., Hu C.S., Kwong D.L.W., Langendijk J.A., Le Q.T., Lee N.Y., Lin J.C., Lu T.X., Mendenhall W.M., O'Sullivan B., Ozyar E., Peters L.J., Rosenthal D.I., Soong Y.L., Tao Y.G., Yom S.S. and Wee J.T., International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma, Radiotherapy and Oncology. 2017. |
| Lee W.M.A., Landscape of Nasopharyngeal Carcinoma Current Management of Loco-Regional Disease, Head and Neck Steering Committee (HNSC) Nasopharyngeal Cancer (NPC) Clinical Trials Planning Meeting (CTPM), 27-28 January 2018, Phoenix, USA. 2018. |
| Lee W.M.A., 鼻咽癌临床靶区(CTV)勾划国际指南要点解读, 第十三届泛珠江区域放射肿瘤学学术大会, 2018年4 月12-15日, 中國湖北武漢, 2018. |
| MAI Z., Lin J., Chiang S.C., Ngan K.C.R., Kwong D.L.W., Ng W.T., Ng A.W.Y., Yuen K.T., Ip D.K.M., Chan Y.H., Lee W.M.A., Ho D.S.Y., Lung M.L. and Lam T.H., Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study, Scientific Reports. 2018, 8: 7052. |
| Ng W.T., Tung S.Y., Lee V.H.F., Ngan K.C.R., Choi C.W., Chan L.L.K., Leung T.W., Siu L.L., Lu T.X., Tan T., Tan E.H., Sze C.K.H., Ng A.W.Y., Yiu H.H.Y., O'Sullivan B., Chappell R. and Lee W.M.A., Concurrent-Adjuvant Chemoradiation Therapy for Stage III-IVB Nasopharyngeal Carcinoma—Exploration for Achieving Optimal 10-Year Therapeutic Ratio, International Journal of Radiation Oncology*Biology*Physics. 2018, 101: 1078-1086. |
| Ng W.T., Wong E.C.Y., Lee V.H.F., Chan Y.W. and Lee W.M.A., Head and neck cancer in Hong Kong, Japanese Journal of Clinical Oncology. 2018, 48(1): 13-21. |
| Ng W.T., Ngan K.C., Kwong D.L.W., Tung S.Y., Yuen K.T., Kam M.K.M., Sze C.K.H., Yiu H.H.Y., Chan L.L.K., Lung M.L. and Lee W.M.A., Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma, International Journal of Radiation Oncology*Biology*Physics. 2018, 100: 630-638. |
| Yang L., Xu Z.Y., Li J.S., Chen Z.J., Lee V.H.F., Lam K.O., Lam T.C., Chiang C.L., Chang T.Y.A., Huse V., Kwong D.L.W. and Lee W.M.A., The feasibility and short-term efficacy of induction chemotherapy with cisplatin and capecitabine followed by concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma, The 25th Annual Scientific Meeting, Hong Kong College of Radiologists, Hong Kong. 2017. |
| Yue P.Y., Ha W.Y., Lau C.C., Cheung F.M.F., Lee W.M.A., Ng W.T., Ngan K.C.R., Yau C.C., Kwong D.L.W., Lung H.L., Mak N.K., Lung M.L. and Wong R.N.S., MicroRNA profiling study reveals miR-150 in association with metastasis in nasopharyngeal carcinoma, Scientific Reports. 2017, 7. |
| Researcher : Lee WY |
| List of Research Outputs |
| Chiang C.L., Yeung C.S.Y., Wong M.Y.P., Lee W.Y., Lee V.H.F., Lee F.A.S. and Wong F.C.S., Stereotactic Body Radiotherapy for Pancreatic Cancer, Hong Kong Journal of Radiology. 2017, 20(4): 303-311. |
| Chiang C.L., Lee W.Y., Yeung C.S.Y., Xu Z.Y., Lee F.A.S. and Chen Z.J., 圖像引導近距离放療（IGBT）在直腸癌根治性治療中的應用 — 單中心初步結果, CSTRO (9-Nov-2017), Beijing, China. 2017. |
| Researcher : Leong ML |
| List of Research Outputs |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members Resulting in Cisplatin Resistance in Nasopharyngeal Carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members in Nasopharyngeal Carcinoma., The 76th Annual Meeting of the Japanese Cancer Association, Tokyo, Japan. Sept 28-30, 2017.. 2017. |
| LEONG M.L., Cheung A.K.L., Kwok C.T.T. and Lung M.L., Functional Characterization of a candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Researcher : Leung TW |
| List of Research Outputs |
| Chan M.F.T., Lam Q.Y.N., Lee V.H.F., Ho P.Y.P., Sze C.K.H., Siu W.K.S., Kwong W.K.P. and Leung T.W., Using the Roach Formula to Stratify Patients with Localised Prostate Cancer Treated with Intensity-modulated Radiotherapy, Hong Kong Journal of Radiology. 2017, 103-109. |
| Lam P.L., Lam T.C., Choi C.W., Lee W.M.A., Yuen K.K. and Leung T.W., The impact of palliative care training for oncologists and integrative palliative service in a public-funded hospital cluster—a retrospective cohort study, Supportive Care in Cancer. 2017. |
| Lau K.S., Lam K.O., Chan W.L.W., Lee V.H.F., Kwong D.L.W. and Leung T.W., S-1 Versus S-1 Plus Cisplatin as First-line Treatment for Metastatic Gastric Cancer, Hong Kong Journal of Radiology. 2017, 318-322. |
| Lee V.H.F., Chan S.Y., Tong C.C., Lam K.O., Kwong D.L.W., Leung T.W. and Lee W.M.A., New hope for advanced nasopharyngeal cancer—an Epstein-Barr virus-driven endemic malignancy?, Translational Cancer Research. 2018, 7: S53-S57. |
| Lee W.M.A., Tung S.Y., Ng W.T., Ngan K.C., Lee V.H.F., Choi C.W., Chan L., Lu T.X., Siu L.L., Tan T.W.K., Ng A.W.Y., Yiu H.H.Y., Leung T.W., O'Sullivan B., Tan E.H. and Chappell R.J., 10-Year Outcome on the Efficacy and Late Toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials), International Journal of Radiation Oncology, Biology, Physics. 2017, 99(2): S46-S46. |
| Ng W.T., Tung S.Y., Lee V.H.F., Ngan K.C.R., Choi C.W., Chan L.L.K., Leung T.W., Siu L.L., Lu T.X., Tan T., Tan E.H., Sze C.K.H., Ng A.W.Y., Yiu H.H.Y., O'Sullivan B., Chappell R. and Lee W.M.A., Concurrent-Adjuvant Chemoradiation Therapy for Stage III-IVB Nasopharyngeal Carcinoma—Exploration for Achieving Optimal 10-Year Therapeutic Ratio, International Journal of Radiation Oncology*Biology*Physics. 2018, 101: 1078-1086. |
| Wong C.L.T., Lee V.H.F., Law A.L.Y., Cui T.Y.S., Shing B.S.Y., Chok K.S.H., Cheung T.T., Chan A.C.Y., Dai W.C., Ng K.K.C., Leung T.W. and Lo C.M., Stereotactic body radiation therapy for hepatocellular carcinoma patients on waiting list for liver transplantation: an interim analysis. , 21st Asian Congress of Surgery. 2017. |
| Researcher : Li Y |
| List of Research Outputs |
| Dai Y., Liu L., Zeng T., Liang J., Song Y., Chen K., Li Y., Chen L., Zhu Y., LI J., Li Y., Xie D., Yuan Y. and Guan X., Overexpression of MUC13, a poor prognostic predictor, promotes cell growth by activating Wnt signaling in hepatocellular carcinoma, American Journal of Pathology. 2018, 188: 378-391. |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Researcher : Liu B |
| List of Research Outputs |
| CAO T., Xiang D., Liu B., Huang T., Tan B., Zeng C., Wang Z., Ming X., ZHANG L., Jin G., Li F., Wu J., Guan X., Lu D. and Fu L., FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma, Oncotarget. 2017, 8: 65957-65968. |
| Researcher : Luk MY |
| List of Research Outputs |
| Yeo W., Luk M.Y., Soong S.I., Yuen T.Y.S., Ng T.Y., Mo F.K.F., Chan K., Wong S.Y., Tsang W.H.J., Leung C., Suen J.J.S. and Ngan K.C.R., Efficacy and tolerability of trastuzumab emtansine in advanced human epidermal growth factor receptor 2–positive breast cancer, Hong Kong Medical Journal. 2018, 24(1): 55-62. |
| Researcher : Lung HL |
| Project Title: | The serum amyloid A1 (SAA1) Polymorphisms as Risk Factors in Esophageal Squamous Cell Carcinoma |
| Investigator(s): | Lung HL, Lung ML, Law SYK |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 11/2013 |
| Project Title: | The effects of the IKKbeta-specific inhibitor PS1145 on tumor formation and metastasis in nasopharyngeal carcinoma |
| Investigator(s): | Lung HL, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2015 |
| List of Research Outputs |
| YANG X., Cheung M.P.L., Wong C.M., Ng I.O.L., Lung H.L. and Cheung M.C.H., Elucidating the role of DLC1, a RhoGTPase-activating protein, in metastatic melanoma, 22nd Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, HKU. 2017. |
| Researcher : Lung ML |
| Project Title: | Candidate tumor suppressor gene, DUSP6, involvement in esophageal and nasopharyngeal carcinomas |
| Investigator(s): | Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2009 |
| Project Title: | Centre for Nasopharyngeal Carcinoma Research |
| Investigator(s): | Lung ML, Chen H, Chiang AKS, Chua DTT, Khong PL, Kwong DLW, Guan X, Tsao GSW, Wu EX |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Areas of Excellence Scheme |
| Start Date: | 01/2010 |
| Project Title: | Advances in Nasopharyngeal Carcinoma Studies |
| Investigator(s): | Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Croucher Advanced Study Institute |
| Start Date: | 11/2014 |
| Project Title: | Secretory NID2, a basement membrane protein facilitating cell adhesion, migration, and metastasis in human cancers |
| Investigator(s): | Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Completion Date: | 12/2017 |
| Project Title: | Functional and Mechanistic Investigation of Frequent p53 Gain-of-Function Mutations in Esophageal Squamous Cell Carcinoma |
| Investigator(s): | Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2015 |
| Project Title: | Functional and mechanistic characterizations of a Candidate Tumor Suppressor Gene, Mirror Image Polydactyly 1, in Nasopharyngeal Carcinoma |
| Investigator(s): | Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2015 |
| Project Title: | Regulation and Clinical Implication of PD-L1 Expression in Esophageal Tumor Cells subjected to Chemotherapy |
| Investigator(s): | Lung ML, Ko JMY, Yu Z |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Matching Grant for Joint Research |
| Start Date: | 11/2015 |
| Project Title: | Targeted Genomics and Functional Studies of Novel Cancer Predisposing Genes for Esophageal Squamous Cell Carcinoma |
| Investigator(s): | Lung ML, Chan KW, Law SYK, Song Y |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2016 |
| Project Title: | Functional studies of Pol K and Pol Q mutations detected at high frequency in high-risk esophageal carcinoma patients |
| Investigator(s): | Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2017 |
| Completion Date: | 03/2018 |
| Project Title: | Establishing platform technology for use of circulating tumor cells for cancer diagnostics and drug testing |
| Investigator(s): | Lung ML, Ko JMY, Dai W |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Platform Technology Funding |
| Start Date: | 06/2017 |
| Project Title: | 3rd ACTC Advances in Circulating Tumor Cells: Liquid biopsy in clinical practice; Clinical usefulness of combined CTC enumeration, EBV DNA, and PET imaging analyses from metastatic NPC |
| Investigator(s): | Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2017 |
| Completion Date: | 10/2017 |
| Project Title: | Translational Studies for Elucidating the Tumor Heterogeneity and Molecular Evolution in Metastatic Gastrointestinal Tract Cancers for Personalized Medicine |
| Investigator(s): | Lung ML, Chan KW, Kwong DLW, Lam KO, Law SYK, Sham PC, Lo WIA |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Theme-based Research Scheme |
| Start Date: | 11/2017 |
| Project Title: | Non-invasive Real-time Monitoring and Next-generation Sequencing of Circulating Tumor Cells for Improved Personalized Treatment of Metastatic Colorectal Cancer Patients |
| Investigator(s): | Lung ML, Lam KO, Ko JMY, Dai W |
| Department: | Clinical Oncology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 03/2018 |
| Project Title: | Clinical application of enumeration and genomic characterization for non-invasive detection and real-time monitoring of circulating tumor cells for esophageal carcinoma |
| Investigator(s): | Lung ML, Law SYK, Kwong DLW, Lam KO, Chan KW, Chiu WHK, Ko JMY, Dai W |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 06/2018 |
| List of Research Outputs |
| CHAI W.Y., Cheung A.K.L., Dai W., Ko J.M.Y., Lee N.P.Y., Chan K.T., Law S.Y.K. and Lung M.L., Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma, Cancer Biomarkers. 2018, 21: 583-590. |
| Chiang S.C., Mai Z., Lin J., Lung M.L. and Lam T.H., Smoking And Risk Of Nasopharyngeal Carcinoma: Preliminary Results From A Hospital-based Case-control Study In Hong Kong, China., IEA World Congress Of Epidemiology 2017. Saitama, Japan. 19-22 Aug, 2017. (poster Presentation).. 2017. |
| DENG M., Cheung A.K.L., Dai W. and Lung M.L., Functional and molecular analysis of the loss-of-function somatic mutations in two NF-κB pathway inhibitors: NFKBIA and CYLD in nasopharyngeal carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Dai W., Ko J.M.Y., Ng H.Y., Zheng H. and Lung M.L., Elucidation of Genetic Susceptibility in Nasopharyngeal Carcinoma by Next Generation Sequencing., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Dai W., Ko J.M.Y., Choi S.S.A., Yu Z., NING L., Zheng H., Gopalan V., Chan K.T., Lee N.P.Y., Chan K.W., Law S.Y.K., Lam A.K.Y. and Lung M.L., Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma, Journal of Pathology. 2017, 242(4): 500-510. |
| GUO C., Ko J.M.Y., Dai W., Law S.Y.K., Lo A. and Lung M.L., Genomic characterization of mutation hotspots related to chemotherapy responses in esophageal squamous cell carcinoma with archived formalin-fixed paraffin-embedded tissues., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Vardhanabhuti V., Khong P.L., Ngan K.C.R., Ng W.T., Kwong D.L.W., Lee V.H.F., Lam K.O. and Lung M.L., Clinical usefulness of cmbined CTC enumeration, EBV DNA, and PET imaging for metastatic nasopharyngeal carcinoma., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Ko J.M.Y., Ng H.Y., Lam K.O. and Lung M.L., PD-L1 expression in CCs of esophageal carcinoma patients., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| LAM S.Y., NING L., Lung M.L. and Ko J.M.Y., Functional characterization of RAD50 germline deleterious variants identified from deep targetd sequencing study of familial esophageal squamous cell carcinoma., HKU Research Postgraduate Symposium. December 6, 2017.. 2017. |
| LAM S.Y., NING L., Ng H.Y., Lung M.L. and Ko J.M.Y., Functional characterization of Rad50 germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| LEI C., Yu Z., NING L., Ko J.M.Y., Wang L.D. and Lung M.L., Functional characterization of FANCD2 in esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members Resulting in Cisplatin Resistance in Nasopharyngeal Carcinoma., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| LEONG M.L., Cheung A.K.L., Dai W., Tsao G.S.W. and Lung M.L., EBV-associated Histone Modifications in the Regulation of DNA Damage Repair Members in Nasopharyngeal Carcinoma., The 76th Annual Meeting of the Japanese Cancer Association, Tokyo, Japan. Sept 28-30, 2017.. 2017. |
| LEONG M.L., Cheung A.K.L., Kwok C.T.T. and Lung M.L., Functional Characterization of a candidate tumor suppressor gene, Mirror image polydactyly 1, in nasopharyngeal carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Lung M.L., (Co-I), GRF Research Grant, “Genomic and functional study of rare deleterious germline mutations in candidate genes associated with familial risk for esophageal carcinoma” HK$971,720, Research Grants Council. 2018. |
| Lung M.L., Advances in Circulating Tumor Cells: Liquid biopsy in clinical practice. Clinical usefulness of combined CTC enumeration, EBV DNA, and PET imaging for metastatic nasopharyngeal carcinoma., Rhodes, Greece, October 4-7, 2017.. 2017. |
| Lung M.L., Days in Molecular Medicine. Emerging Asian Epidemic of Cancer and Heart Disease. New insights into nasopharyngeal carcinoma, Organized by the Karolinska Institute, Sweden. Hong Kong. March 1-2, 2018. Invited speaker. 2018. |
| Lung M.L., Frontiers in Infection-associated Cancer. Using next-generation sequencing approaches for new insights into nasopharyngeal carcinoma, Bangkok, Thailand. June 16-20, 2018. Plenary speaker. 2018. |
| Lung M.L., Functional and genomic studies of esophageal squamous cell carcinoma, Institute of Life and Health Engineering, Jinan University, Guangzhou, China, Nov 7, 2017. 2017. |
| Lung M.L., New insights in NPC detection utilizing CTC enumeration and NGS analysis, Gordon Research Conference on Nasopharyngeal Carcinoma, Hong Kong. June 24-29, 2018. 2018. |
| Lung M.L., Research grant, “Clinical application of enumeration and genomic characterization for non-invasive detection and real-time monitoring of circulating tumor cells for esophageal carcinoma” HK$1,199,732, Health Medical Research Fund. 2018. |
| Lung M.L., Whole-exome sequencing analysis of NPC, NPC AoE Public Research Symposium, June 22, 2018. Hong Kong. 2018. |
| Lung M.L., “Non-invasive real-time monitoring and next-generation sequencing of circulating tumor cells for improved personalized treatment of metastatic colorectal cancer patients” HK$956,000, SK Yee Medical Foundation. 2018. |
| Lung M.L., “Translational Studies for Elucidation the Tumor Heterogeneity and Molecular Evolution in Metastatic Gastrointestinal Tract Cancers for Personalized Medicine” HK$33,333,000, Theme-based Research Scheme. 2017. |
| MAI Z., Lin J., Chiang S.C., Ngan K.C.R., Kwong D.L.W., Ng W.T., Ng A.W.Y., Yuen K.T., Ip D.K.M., Chan Y.H., Lee W.M.A., Ho D.S.Y., Lung M.L. and Lam T.H., Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study, Scientific Reports. 2018, 8: 7052. |
| Mai Z., Lin J., Chan W., Ip D.K.M., Lung M.L. and Lam T.H., Intake of fish oil/cod-liver oil/omega-3 and vitamin D supplements associated with lower risk of nasopharyngeal carcinoma: preliminary results from a case-control study in Hong Kong, China., IEA World Congress of Epidemiology 2017. Saitama, Japan. 19-22 Aug, 2017. (Poster presentation). 2017. |
| NING L., Ko J.M.Y., LEI C., Wang L.D. and Lung M.L., Investigating the germline deleterious rare variants for genetic susceptibility of esophagus squamous cell carcinoma by target sequencing., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| NING L., Ko J.M.Y. and Lung M.L., Targeted gene sequencing studies of CDKN2B-AS1 in nasopharyngeal carcinoma genetic susceptibility., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ng H.Y. and Lung M.L., Chemotherapy induces PD-L1 in esophageal squamous cell carcinoma, 25th Biennial Congress of the European Association for Cancer Research. 2018. |
| Ng W.T., Ngan K.C., Kwong D.L.W., Tung S.Y., Yuen K.T., Kam M.K.M., Sze C.K.H., Yiu H.H.Y., Chan L.L.K., Lung M.L. and Lee W.M.A., Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma, International Journal of Radiation Oncology*Biology*Physics. 2018, 100: 630-638. |
| Yip Y.L., Lin W., Deng W., Jia L.J., Lo K.W., Busson P., Vérillaud B., Liu X., Tsang C.M., Lung M.L. and Tsao G.S.W., Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein–Barr virus reactivation, Laboratory Investigation. 2018, 98: 1093-1104. |
| Yip Y.L., Lin W., Deng W., Jia L.J., Lo K.W., Busson P., Verillaud B., Liu X., Tsang C.M., Lung M.L. and Tsao G.S.W., Establishment of a nasopharyngeal carcinoma cell line capable to undergo EBV lytic reactivation, Gordon Research Conference: Nasopharyngeal Carcinoma 2018. |
| Yu Z. and Lung M.L., Functional characterization of potential gain-of-function p53 mutants in esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Yue P.Y., Ha W.Y., Lau C.C., Cheung F.M.F., Lee W.M.A., Ng W.T., Ngan K.C.R., Yau C.C., Kwong D.L.W., Lung H.L., Mak N.K., Lung M.L. and Wong R.N.S., MicroRNA profiling study reveals miR-150 in association with metastasis in nasopharyngeal carcinoma, Scientific Reports. 2017, 7. |
| Researcher : MING X |
| List of Research Outputs |
| CAO T., Xiang D., Liu B., Huang T., Tan B., Zeng C., Wang Z., Ming X., ZHANG L., Jin G., Li F., Wu J., Guan X., Lu D. and Fu L., FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma, Oncotarget. 2017, 8: 65957-65968. |
| LAU C.C., Ng K.Y., Wong T.L., Tong M., Lee T.K., Ming X., Law S.Y.K., Lee N.P.Y., Cheung A., Qin Y.R., Chan K.W., Ning W., Guan X. and Ma S.K.Y., FSTL1 promotes metastasis and chemoresistance in esophageal squamous cell carcinoma through NFκB-BMP signaling crosstalk, Cancer Research. 2017, 77(21): 5886-5899. |
| MING X., Zhang X., CAO T., ZHANG L., QI J., TANG X., CUI Y., Zhang B., Li Y., Qin Y. and Guan X., RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression, Theranostics. 2018, 8: 185-198. |
| Researcher : Ming X |
| List of Research Outputs |
| CAO T., Xiang D., Liu B., Huang T., Tan B., Zeng C., Wang Z., Ming X., ZHANG L., Jin G., Li F., Wu J., Guan X., Lu D. and Fu L., FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma, Oncotarget. 2017, 8: 65957-65968. |
| LAU C.C., Ng K.Y., Wong T.L., Tong M., Lee T.K., Ming X., Law S.Y.K., Lee N.P.Y., Cheung A., Qin Y.R., Chan K.W., Ning W., Guan X. and Ma S.K.Y., FSTL1 promotes metastasis and chemoresistance in esophageal squamous cell carcinoma through NFκB-BMP signaling crosstalk, Cancer Research. 2017, 77(21): 5886-5899. |
| MING X., Zhang X., CAO T., ZHANG L., QI J., TANG X., CUI Y., Zhang B., Li Y., Qin Y. and Guan X., RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression, Theranostics. 2018, 8: 185-198. |
| Researcher : NING L |
| List of Research Outputs |
| Dai W., Ko J.M.Y., Choi S.S.A., Yu Z., NING L., Zheng H., Gopalan V., Chan K.T., Lee N.P.Y., Chan K.W., Law S.Y.K., Lam A.K.Y. and Lung M.L., Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma, Journal of Pathology. 2017, 242(4): 500-510. |
| LAM S.Y., NING L., Lung M.L. and Ko J.M.Y., Functional characterization of RAD50 germline deleterious variants identified from deep targetd sequencing study of familial esophageal squamous cell carcinoma., HKU Research Postgraduate Symposium. December 6, 2017.. 2017. |
| LAM S.Y., NING L., Ng H.Y., Lung M.L. and Ko J.M.Y., Functional characterization of Rad50 germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| LEI C., Yu Z., NING L., Ko J.M.Y., Wang L.D. and Lung M.L., Functional characterization of FANCD2 in esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| NING L., Ko J.M.Y., LEI C., Wang L.D. and Lung M.L., Investigating the germline deleterious rare variants for genetic susceptibility of esophagus squamous cell carcinoma by target sequencing., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| NING L., Ko J.M.Y. and Lung M.L., Targeted gene sequencing studies of CDKN2B-AS1 in nasopharyngeal carcinoma genetic susceptibility., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Researcher : Ng HY |
| Project Title: | 25th Biennial Congress of the European Association for Cancer Reserach; Chemotherapy induces PD-L1 in esophageal squamous cell carcinoma |
| Investigator(s): | Ng HY |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2018 |
| Completion Date: | 07/2018 |
| List of Research Outputs |
| Dai W., Ko J.M.Y., Ng H.Y., Zheng H. and Lung M.L., Elucidation of Genetic Susceptibility in Nasopharyngeal Carcinoma by Next Generation Sequencing., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Ko J.M.Y., Ng H.Y., Lam K.O. and Lung M.L., PD-L1 expression in CCs of esophageal carcinoma patients., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| LAM S.Y., NING L., Ng H.Y., Lung M.L. and Ko J.M.Y., Functional characterization of Rad50 germline deleterious variants identified from deep targeted sequencing study of familial esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Ng H.Y. and Lung M.L., Chemotherapy induces PD-L1 in esophageal squamous cell carcinoma, 25th Biennial Congress of the European Association for Cancer Research. 2018. |
| Researcher : Ng KY |
| List of Research Outputs |
| Luk S.T.C., Tong M., Ng K.Y., Yip K.Y.L., Guan X. and Ma S.K.Y., Abstract 4352: Identification of ZFP42/REX1 as a regulator of cancer stemness in CD133+ liver cancer stem cells by genome-wide DNA methylation analysis , AACR Annul Meeting 2017; April 1-5, 2017, Washington DC, USA. 2017, 77: 4352-4352. |
| Researcher : Ng WT |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| Chang T.Y.A., Tan L.T., Duke S. and Ng W.T., Challenges for Quality Assurance of Target Volume Delineation in Clinical Trials, Frontiers in Oncology. 2017, 7. |
| Lee W.M.A., Tung S.Y., Ng W.T., Ngan K.C., Lee V.H.F., Choi C.W., Chan L., Lu T.X., Siu L.L., Tan T.W.K., Ng A.W.Y., Yiu H.H.Y., Leung T.W., O'Sullivan B., Tan E.H. and Chappell R.J., 10-Year Outcome on the Efficacy and Late Toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials), International Journal of Radiation Oncology, Biology, Physics. 2017, 99(2): S46-S46. |
| Lee W.M.A., Ng W.T., Pan J.J., Poh S.S., Ahn Y.C., AlHussain H., Corry J., Grau C., Grégoire V., Harrington K.J., Hu C.S., Kwong D.L.W., Langendijk J.A., Le Q.T., Lee N.Y., Lin J.C., Lu T.X., Mendenhall W.M., O'Sullivan B., Ozyar E., Peters L.J., Rosenthal D.I., Soong Y.L., Tao Y.G., Yom S.S. and Wee J.T., International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma, Radiotherapy and Oncology. 2017. |
| MAI Z., Lin J., Chiang S.C., Ngan K.C.R., Kwong D.L.W., Ng W.T., Ng A.W.Y., Yuen K.T., Ip D.K.M., Chan Y.H., Lee W.M.A., Ho D.S.Y., Lung M.L. and Lam T.H., Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study, Scientific Reports. 2018, 8: 7052. |
| Ng W.T., Tung S.Y., Lee V.H.F., Ngan K.C.R., Choi C.W., Chan L.L.K., Leung T.W., Siu L.L., Lu T.X., Tan T., Tan E.H., Sze C.K.H., Ng A.W.Y., Yiu H.H.Y., O'Sullivan B., Chappell R. and Lee W.M.A., Concurrent-Adjuvant Chemoradiation Therapy for Stage III-IVB Nasopharyngeal Carcinoma—Exploration for Achieving Optimal 10-Year Therapeutic Ratio, International Journal of Radiation Oncology*Biology*Physics. 2018, 101: 1078-1086. |
| Ng W.T., Wong E.C.Y., Lee V.H.F., Chan Y.W. and Lee W.M.A., Head and neck cancer in Hong Kong, Japanese Journal of Clinical Oncology. 2018, 48(1): 13-21. |
| Ng W.T., Ngan K.C., Kwong D.L.W., Tung S.Y., Yuen K.T., Kam M.K.M., Sze C.K.H., Yiu H.H.Y., Chan L.L.K., Lung M.L. and Lee W.M.A., Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma, International Journal of Radiation Oncology*Biology*Physics. 2018, 100: 630-638. |
| Researcher : Ngan KC |
| List of Research Outputs |
| Lee W.M.A., Tung S.Y., Ng W.T., Ngan K.C., Lee V.H.F., Choi C.W., Chan L., Lu T.X., Siu L.L., Tan T.W.K., Ng A.W.Y., Yiu H.H.Y., Leung T.W., O'Sullivan B., Tan E.H. and Chappell R.J., 10-Year Outcome on the Efficacy and Late Toxicities Attributed to the Addition of Concurrent-Adjuvant Chemotherapy for Stage III-IVB Nasopharyngeal Carcinoma (Combined Analyses of the NPC-9901 and NPC-9902 Trials), International Journal of Radiation Oncology, Biology, Physics. 2017, 99(2): S46-S46. |
| Ng W.T., Ngan K.C., Kwong D.L.W., Tung S.Y., Yuen K.T., Kam M.K.M., Sze C.K.H., Yiu H.H.Y., Chan L.L.K., Lung M.L. and Lee W.M.A., Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma, International Journal of Radiation Oncology*Biology*Physics. 2018, 100: 630-638. |
| Researcher : Ngan KCR |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| Cheung K.M., Ngan K.C.R., Chow J.C.H., Lee T.Y., Li K.W.S., Cheng H.C., Leung C.W.L., Yiu H.H.Y., Yau S., Au J.S.K. and Wong K.H., Can Neoadjuvant Chemotherapy before Definitive Surgery Improve Outcome in Operable Stage IVA Oral Cavity Cancers?, Hong Kong Journal of Radiology. 2018, 21: 124-131. |
| Chinag R., Lam T.H., Wong K.H., Chan C.C., Chao D.V., Cheung A.N., Fan C.Y., Ho J., Hui E.P., Law C.K., Law W.L., Loong H.H., Ngan K.C.R., Tsang T.H., Wong M.C., Yeung R.M. and Ying A.C., Recommendations on prevention and screening for breast cancer in Hong Kong, Hong Kong Medical Journal. 2018, 24(3): 298-306. |
| Chow J.C.H., Au K.H., Mange O.W.K., Cheung K.M. and Ngan K.C.R., Risk, pattern and survival impact of second primary tumors in patients with nasopharyngeal carcinoma following definitive intensity-modulated radiotherapy, Asia-Pacific Journal of Clinical Oncology. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Vardhanabhuti V., Khong P.L., Ngan K.C.R., Ng W.T., Kwong D.L.W., Lee V.H.F., Lam K.O. and Lung M.L., Clinical usefulness of cmbined CTC enumeration, EBV DNA, and PET imaging for metastatic nasopharyngeal carcinoma., 3rd ACTC Advances in Circulating tumor cells: Liquid biopsy in clinical practice. Rhodes, Greece. Oct 4-7, 2017.. 2017. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| MAI Z., Lin J., Chiang S.C., Ngan K.C.R., Kwong D.L.W., Ng W.T., Ng A.W.Y., Yuen K.T., Ip D.K.M., Chan Y.H., Lee W.M.A., Ho D.S.Y., Lung M.L. and Lam T.H., Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study, Scientific Reports. 2018, 8: 7052. |
| Ng W.T., Tung S.Y., Lee V.H.F., Ngan K.C.R., Choi C.W., Chan L.L.K., Leung T.W., Siu L.L., Lu T.X., Tan T., Tan E.H., Sze C.K.H., Ng A.W.Y., Yiu H.H.Y., O'Sullivan B., Chappell R. and Lee W.M.A., Concurrent-Adjuvant Chemoradiation Therapy for Stage III-IVB Nasopharyngeal Carcinoma—Exploration for Achieving Optimal 10-Year Therapeutic Ratio, International Journal of Radiation Oncology*Biology*Physics. 2018, 101: 1078-1086. |
| Yeo W., Luk M.Y., Soong S.I., Yuen T.Y.S., Ng T.Y., Mo F.K.F., Chan K., Wong S.Y., Tsang W.H.J., Leung C., Suen J.J.S. and Ngan K.C.R., Efficacy and tolerability of trastuzumab emtansine in advanced human epidermal growth factor receptor 2–positive breast cancer, Hong Kong Medical Journal. 2018, 24(1): 55-62. |
| Yue P.Y., Ha W.Y., Lau C.C., Cheung F.M.F., Lee W.M.A., Ng W.T., Ngan K.C.R., Yau C.C., Kwong D.L.W., Lung H.L., Mak N.K., Lung M.L. and Wong R.N.S., MicroRNA profiling study reveals miR-150 in association with metastasis in nasopharyngeal carcinoma, Scientific Reports. 2017, 7. |
| Researcher : QI J |
| List of Research Outputs |
| MING X., Zhang X., CAO T., ZHANG L., QI J., TANG X., CUI Y., Zhang B., Li Y., Qin Y. and Guan X., RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression, Theranostics. 2018, 8: 185-198. |
| Researcher : Siu WKS |
| List of Research Outputs |
| Chan M.F.T., Lam Q.Y.N., Lee V.H.F., Ho P.Y.P., Sze C.K.H., Siu W.K.S., Kwong W.K.P. and Leung T.W., Using the Roach Formula to Stratify Patients with Localised Prostate Cancer Treated with Intensity-modulated Radiotherapy, Hong Kong Journal of Radiology. 2017, 103-109. |
| Researcher : So TH |
| List of Research Outputs |
| Chiang C.L., Choi C.W., Mui W.H. and So T.H., 261OCost-effectiveness analysis of additional abiraterone for hormone-sensitive metastatic prostatic cancer treated with androgen deprivation therapy (ADT), Annals of Oncology. 2017, 28: 80. |
| Chiang C.L., So T.H., Chen Z.J., Lee V.H.F. and Lee W.M.A., Pursuit of Excellence in the Management of Nasopharyngeal Carcinoma (NPC), International Journal of Head and Neck Science. 2017, 1(4): 199-211. |
| Lam K.O., Shek W.H., Yang L., So T.H., Chiang C.L., Lam T.C., Lee V.H.F., Chen Z.J. and Lee W.M.A., BRAF-mutated metastatic colorectal cancer: Is intensive therapy and metastasectomy really necessary, The 13th Pan-Pearl-River Area Congress of Radiation Oncology, Wuhan, China. 2018. |
| Lam K.O., Law B., Chan W., Wong Y.H.I., Chiu W.H.K., So T.H., Chan S., Lee V.H.F., Chu K.M., Kwong D.L.W. and Law S.Y.K., P-066Feasibility study of intraperitoneal docetaxel combined with intravenous cisplatin and oral S-1 for gastric cancer patients with peritoneal carcinomatosis, Annals of Oncology. 2018, 29. |
| Lau H.P., Chow A.Y.M., Wong F.K.D., Chan J.S.M., Chan C.H.Y., Ho R.T.H., So T.H., Lam T.C., Lee V.H.F. and Lee W.M.A., Study Protocol of a Randomized Controlled Trial Comparing Integrative Body-Mind-Spirit Intervention and Cognitive Behavioural Therapy in Fostering Quality of Life of Patients with Lung Cancer and their Family Caregivers., Journal of Evidence-informed Social Work. 2018, 15(3): 258-276. |
| So T.H., Lee V.H.F. and Lam K.O., Aflibercept-induced Nephrotic Syndrome, 阿普西柏誘發的腎病綜合症, Hong Kong Journal of Radiology. 2017. |
| Researcher : Soong SI |
| List of Research Outputs |
| Chang T.Y.A., Chan O.S.H., Soong S.I., Hung A.W.M., Chan L.L.K. and Yeung M.W.R., Evaluating clinical outcome and toxicity for stereotactic body radiotherapy in oligometastatic lung disease, In: Louisa C Lui, Kam-Hung Wong, Rebecca Yeung and Joav Merrick, In Palliative Care: Oncology Experience from Hong Kong. 2017, 135-154. |
| Yeo W., Luk M.Y., Soong S.I., Yuen T.Y.S., Ng T.Y., Mo F.K.F., Chan K., Wong S.Y., Tsang W.H.J., Leung C., Suen J.J.S. and Ngan K.C.R., Efficacy and tolerability of trastuzumab emtansine in advanced human epidermal growth factor receptor 2–positive breast cancer, Hong Kong Medical Journal. 2018, 24(1): 55-62. |
| Researcher : Sze CKH |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| Chan M.F.T., Lam Q.Y.N., Lee V.H.F., Ho P.Y.P., Sze C.K.H., Siu W.K.S., Kwong W.K.P. and Leung T.W., Using the Roach Formula to Stratify Patients with Localised Prostate Cancer Treated with Intensity-modulated Radiotherapy, Hong Kong Journal of Radiology. 2017, 103-109. |
| Ng W.T., Tung S.Y., Lee V.H.F., Ngan K.C.R., Choi C.W., Chan L.L.K., Leung T.W., Siu L.L., Lu T.X., Tan T., Tan E.H., Sze C.K.H., Ng A.W.Y., Yiu H.H.Y., O'Sullivan B., Chappell R. and Lee W.M.A., Concurrent-Adjuvant Chemoradiation Therapy for Stage III-IVB Nasopharyngeal Carcinoma—Exploration for Achieving Optimal 10-Year Therapeutic Ratio, International Journal of Radiation Oncology*Biology*Physics. 2018, 101: 1078-1086. |
| Ng W.T., Ngan K.C., Kwong D.L.W., Tung S.Y., Yuen K.T., Kam M.K.M., Sze C.K.H., Yiu H.H.Y., Chan L.L.K., Lung M.L. and Lee W.M.A., Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma, International Journal of Radiation Oncology*Biology*Physics. 2018, 100: 630-638. |
| Researcher : Tong CC |
| List of Research Outputs |
| Lee V.H.F., Chan S.Y., Tong C.C., Lam K.O., Kwong D.L.W., Leung T.W. and Lee W.M.A., New hope for advanced nasopharyngeal cancer—an Epstein-Barr virus-driven endemic malignancy?, Translational Cancer Research. 2018, 7: S53-S57. |
| Researcher : Tsang HK |
| List of Research Outputs |
| Ko J.M.Y., Tsang H.K., Dai W., CHOI S.S...A., LEONG M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Blood telomere length associates with NPC risk and survival., Gordon Research Conference on Nasopharyngeal Carcinoma. Hong Kong, June 24-29, 2018.. 2018. |
| Ko J.M.Y., Tsang H.K., Dai W., Choi S.S.A., Leong M.L., Ngan K.C.R., Kwong D.L.W., Cheng A., Lee W.M.A., Ng W.T., Tung S., Lee V.H.F., Lam K.O., Chan K.C. and Lung M.L., Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese, International Journal of Cancer. 2018. |
| Researcher : Tsang JWH |
| Project Title: | Breast Cancer Awareness, Spectrum of Breast Cancer with Particular Reference to Triple Negative Breast Cancer in the Hong Kong Chinese Population |
| Investigator(s): | Tsang WHJ, Chua DTT, Kwong A, Khoo US, Lam WWT |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 10/2008 |
| Project Title: | General Awareness and Attitudes towards Cancer Clinical Trials among Cancer Patients in Hong Kong. |
| Investigator(s): | Tsang WHJ, Yung ST, Lam WWT |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2011 |
| Project Title: | Study of the OncotypeDx 21-gene assay and its impact on the treatment decision making process among Hong Kong Chinese breast cancer patients |
| Investigator(s): | Tsang WHJ, Khoo US |
| Department: | Clinical Oncology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 08/2012 |
| List of Research Outputs |
| Researcher : Tsang WHJ |
| Project Title: | Breast Cancer Awareness, Spectrum of Breast Cancer with Particular Reference to Triple Negative Breast Cancer in the Hong Kong Chinese Population |
| Investigator(s): | Tsang WHJ, Chua DTT, Kwong A, Khoo US, Lam WWT |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 10/2008 |
| Project Title: | General Awareness and Attitudes towards Cancer Clinical Trials among Cancer Patients in Hong Kong. |
| Investigator(s): | Tsang WHJ, Yung ST, Lam WWT |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2011 |
| Project Title: | Study of the OncotypeDx 21-gene assay and its impact on the treatment decision making process among Hong Kong Chinese breast cancer patients |
| Investigator(s): | Tsang WHJ, Khoo US |
| Department: | Clinical Oncology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 08/2012 |
| List of Research Outputs |
| Lam W.W.T., Kwong A., Suen T.K.D., Tsang W.H.J., Soong I., Yau T.K., Yeo W., Suen J., Ho W.M., Wong K.Y., Sze W.K., Ng A.W.Y. and Fielding R., Factors predicting patient satisfaction in women with advanced breast cancer: a prospective study, BMC Cancer. 2018, 18(1): 162. |
| Researcher : WANG Y |
| List of Research Outputs |
| Kam N.W. and WANG Y., An inflammation-related nomogram for predicting the survival of patients with non-small cell lung cancer after pulmonary lobectomy., In: Wang Y, Qu X, Kam NW, Wang K, Shen H, Liu Q, Du J., BMC Cancer. 2018. |
| Researcher : Wong CSF |
| List of Research Outputs |
| Chiang C.L., Lee F.A.S., Wong Y.W.V., Poon C.M., Choi C.K.K., Wong C.S.F., Sze W.K. and Tung S.Y., Short-course Preoperative Radiotherapy with Delayed Surgery for Locally Advanced Rectal Cancer, Hong Kong Journal of Radiology. 2017, 20(4): 312-317. |
| Ho H.M., Chiang C.L., Lee A.S., Chan C.H., Yeung Y.S., Choi K.K., Wong C.S.F. and Tung Y., Albumin-Bilirubin (ALBI) versus Child-Pugh (CP) Score as a predictor of survival after Stereotactic Body Radiotherapy (SBRT) in Hepatocellular Carcinoma (HCC), ASTRO’s 59th Annual meeting, 25 September 2017, San Diego, United States. 2017. |
| Lee S.F., Chiang C.L., Lee F.A.S., Wong Y.W., Poon C.M.M., Wong C.S.F. and Tung S.Y., Outcome of neoadjuvant chemoradiation in MRI staged locally advanced rectal cancer: Retrospective analysis of 123 Chinese patients, Journal of the Formosan Medical Association. 2017. |
| Researcher : Wong YWV |
| List of Research Outputs |
| Chiang C.L., Lee F.A.S., Wong Y.W.V., Poon C.M., Choi C.K.K., Wong C.S.F., Sze W.K. and Tung S.Y., Short-course Preoperative Radiotherapy with Delayed Surgery for Locally Advanced Rectal Cancer, Hong Kong Journal of Radiology. 2017, 20(4): 312-317. |
| Researcher : XIAN Z |
| List of Research Outputs |
| Zhou L., Siu H.C., LOONG H.C., Tong M., Wong T.L., Chai S., XIAN Z., Guan X., Wong D.K.H., Man K., Lo C.M., Yan H.H.N., Leung S.Y., Clevers H. and Ma S.K.Y., Establishment Of Human Primary Hepatocellular Carcinoma-derived Organoid Cultures For Disease Modeling And Drug Screening, International Society For Stem Cell Research (ISSCR) 2018 Annal Meeting. 2018. |
| Researcher : YAN Q |
| List of Research Outputs |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Researcher : YU D |
| List of Research Outputs |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Researcher : Yeung MWR |
| List of Research Outputs |
| Chan O.S.H., Lee V.H.F., Mok T.S.K., Mo F., Chang T.Y.A. and Yeung M.W.R., The Role of Radiotherapy in Epidermal Growth Factor Receptor Mutation-positive Patients with Oligoprogression: A Matched-cohort Analysis, Clinical Oncology. 2017, 29: 568-575. |
| Chang T.Y.A., Chan O.S.H., Soong S.I., Hung A.W.M., Chan L.L.K. and Yeung M.W.R., Evaluating clinical outcome and toxicity for stereotactic body radiotherapy in oligometastatic lung disease, In: Louisa C Lui, Kam-Hung Wong, Rebecca Yeung and Joav Merrick, In Palliative Care: Oncology Experience from Hong Kong. 2017, 135-154. |
| Researcher : Yu Z |
| Project Title: | Functional and mechanistic analysis of PHF11 in esophageal squamous cell carcinoma epigenetics |
| Investigator(s): | Yu Z, Lung ML |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2015 |
| Project Title: | AACR Annual Meeting 2018; Functional characterization of potential gain-of-function p53 mutants in esophageal squamous cell carcinoma |
| Investigator(s): | Yu Z |
| Department: | Clinical Oncology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 04/2018 |
| Completion Date: | 04/2018 |
| List of Research Outputs |
| Dai W., Ko J.M.Y., Choi S.S.A., Yu Z., NING L., Zheng H., Gopalan V., Chan K.T., Lee N.P.Y., Chan K.W., Law S.Y.K., Lam A.K.Y. and Lung M.L., Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma, Journal of Pathology. 2017, 242(4): 500-510. |
| LEI C., Yu Z., NING L., Ko J.M.Y., Wang L.D. and Lung M.L., Functional characterization of FANCD2 in esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Yu Z. and Lung M.L., Functional characterization of potential gain-of-function p53 mutants in esophageal squamous cell carcinoma., 109th American Association for Cancer Research. Chicago, Illinois, USA, April 14-18, 2018.. 2018. |
| Researcher : Yuen KK |
| List of Research Outputs |
| Lam P.L., Lam T.C., Choi C.W., Lee W.M.A., Yuen K.K. and Leung T.W., The impact of palliative care training for oncologists and integrative palliative service in a public-funded hospital cluster—a retrospective cohort study, Supportive Care in Cancer. 2017. |
| Researcher : Yuen KT |
| List of Research Outputs |
| Au G.K.H., Ngan K.C.R., Ng A.W.Y., Poon D.M.C., Ng W.T., Yuen K.T., Lee V.H.F., Tung S.Y., Chan A.T.C., Sze C.K.H., Cheng C.K., Lee W.M.A., Kwong D.L.W. and Tam A.H.P., Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study), Oral Oncology. 2018, 77: 16-21. |
| MAI Z., Lin J., Chiang S.C., Ngan K.C.R., Kwong D.L.W., Ng W.T., Ng A.W.Y., Yuen K.T., Ip D.K.M., Chan Y.H., Lee W.M.A., Ho D.S.Y., Lung M.L. and Lam T.H., Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study, Scientific Reports. 2018, 8: 7052. |
| Ng W.T., Ngan K.C., Kwong D.L.W., Tung S.Y., Yuen K.T., Kam M.K.M., Sze C.K.H., Yiu H.H.Y., Chan L.L.K., Lung M.L. and Lee W.M.A., Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma, International Journal of Radiation Oncology*Biology*Physics. 2018, 100: 630-638. |
| Researcher : ZHANG L |
| List of Research Outputs |
| CAO T., Xiang D., Liu B., Huang T., Tan B., Zeng C., Wang Z., Ming X., ZHANG L., Jin G., Li F., Wu J., Guan X., Lu D. and Fu L., FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma, Oncotarget. 2017, 8: 65957-65968. |
| MING X., Zhang X., CAO T., ZHANG L., QI J., TANG X., CUI Y., Zhang B., Li Y., Qin Y. and Guan X., RHCG suppresses tumorigenicity and metastasis in esophageal squamous cell carcinoma via inhibiting NF-κB signaling and MMP1 expression, Theranostics. 2018, 8: 185-198. |
| Researcher : ZHANG Y |
| List of Research Outputs |
| YAN Q., JIANG L., LIU M., YU D., ZHANG Y., LI Y., FANG S., Li Y., Zhu Y., Yuan Y. and Guan X., ANGPTL1 interacts with integrin α1β1 to suppress HCC angiogenesis and metastasis by inhibiting JAK2/STAT3 signaling, Cancer Research. 2017, 77: 5831-5845. |
| Researcher : Zheng H |
| List of Research Outputs |
| Dai W., Ko J.M.Y., Choi S.S.A., Yu Z., NING L., Zheng H., Gopalan V., Chan K.T., Lee N.P.Y., Chan K.W., Law S.Y.K., Lam A.K.Y. and Lung M.L., Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma, Journal of Pathology. 2017, 242(4): 500-510. |