School of Chinese Medicine

SCHOOL OF CHINESE MEDICINE

Researcher : CHAN WCC

List of Research Outputs

CHAN W.C.C., Lo K.C. and Li L., Acupressure for Frail Older Adults under Residential Care – a randomized controlled trial, 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Guangzhou, Chian, 2017.

Researcher : CHEN X

List of Research Outputs

CHEN X., LAM K.H., CHEN Q., Leung G.P.H., Tang S.C.W., Sze C.W.S., Xiao J., Feng F., Wang Y., Zhang Y. and Zhang Z., Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats, Food and Chemical Toxicology. 2017, 110: 49-61.

CHEN X., Leung G.P.H., Zhang Z., Xiao J.B., Lao L., Feng F., Mak J.C.W., Wang Y., Sze C.W.S. and Zhang Y., Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil, Food and Chemical Toxicology. 2017, 107: 248-260.

Chen H., GUAN B., Chen X., Chen X., Li C., Qiu J., Yang D., Liu K., Qi S. and Shen J., Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway, Translational Stroke Research. Springer US, 2017.

Chen X., Zhou B., Yan T., Wu H., Feng J., Chen H., GAO C., Peng T., Yang D. and Shen J., Peroxynitrite enhances self-renewal, proliferation and neuronal differentiation of neural stem/progenitor cells through activating HIF-1α and Wnt/β-catenin signaling pathway, Free Radical Biology and Medicine. 2018, 117: 158-167.

Researcher : CHENG Y

List of Research Outputs

CHENG Y., Li X.C., Tse H.F. and Rong J., Gallic Acid-L-Leucine Conjugate Protects Mice against LPS-Induced Inflammation and Sepsis via Correcting Proinflammatory Lipid Mediator Profiles and Oxidative Stress, Oxidative Medicine and Cellular Longevity. 2018, 2018: 1-14.

CHENG Y. and Rong J., Macrophage Polarization as a Therapeutic Target in Myocardial Infarction, Current Drug Targets. 2017, 18.

CHENG Y. and Rong J., Prostaglandin 15-keto PGF2α skews macrophage M1/M2 polarization against myocardial ischemia reperfusion injury via covalent modification of glycolytic enzyme PKM2, The 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), August 18 - 20, 2017, Guangzhou, China. 2017.

CHENG Y., Feng Y., Xia Z., Li X.C. and Rong J., ω-Alkynyl arachidonic acid promotes anti-inflammatory macrophage M2 polarization against acute myocardial infarction via regulating the cross-talk between PKM2, HIF-1α and iNOS, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2017, 1862: 1595-1605.

LUO D., Guo Y., CHENG Y., Zhao J., Wang Y. and Rong J., Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways, Aging. 2017.

Wei J., CHENG Y., Guo W.H., Wang D.C., Zhang Q., Li D., Rong J. and Gao J.M., Molecular Diversity and Potential Anti-neuroinflammatory Activities of Cyathane Diterpenoids from the Basidiomycete Cyathus africanus, Scientific Reports. 2017, 7.

Researcher : Chan YT

List of Research Outputs

Wang N., Tan H.Y.H., Chan Y.T., GUO W., LI S. and Feng Y., Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde, Oncotarget. 2017, 8.

Researcher : Chen H

Project Title:	The protective role of wfb-120, a novel small molecule from ganoderma lucidum, in renal fibrosis
Investigator(s):	Chen H, Lao L, Feng Y, Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for New Staff
Start Date:	06/2015
Completion Date:	02/2018

Project Title:	The latent TGF-β protects against diabetic kidney disease via GARP-latent TGF-β mediated anti-inflammation: mechanism and therapeutic potential
Investigator(s):	Chen H, Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2017

Project Title:	A novel small molecule from Lingzhi ameliorates cisplatin-induced acute kidney Injury via AMPK/mTOR-MAPK-NFkB crosstalk pathways: a pilot study
Investigator(s):	Chen H, Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	06/2017

Project Title:	WNT1-inducible signaling pathway protein-1 enhances diabetic kidney diseases via TGF-β/Smad and NF-kB crosstalk pathways: mechanism and therapeutic potential
Investigator(s):	Chen H, Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:	07/2017
Completion Date:	11/2017

List of Research Outputs

Au K.Y., Chen H., Lam W.C., Chong C.O., Lau A., Vardhanabhuti V., Mak K.C., Jiang F., Lam W.Y., Wu F.M., Chan H.N., Ng Y.W., Ng B.F.L., Ziea E.T. and Lao L., Sinew acupuncture for knee osteoarthritis: study protocol for a randomized sham-controlled trial, BMC Complementary and Alternative Medicine. 2018, 18.

Chan L.K., Ganotice F.J.A., Wong F.K.Y., Lau W.C.S., Bridges S.M., Chan C.H.Y., Chan N.K., Chan W.L.P., Chen H., Chen J.Y., Chu K.P.J., Ho C.C., Ho J.M.C., Lam T.P., Lam S.F., Li Q., Shen J., Tanner J.A., Tso W.Y.W., Wong A.K.C., Wong G.T.C., Wong J.Y.H., Wong N.S., Worsley A.J., Yu L.K. and Yum T.P., Implementation of an interprofessional team-based learning program involving seven undergraduate health and social care programs from two universities, and students’ evaluation of their readiness for interprofessional learning, BMC Medical Education. 2017, 17.

Chen H. and Shen J., 13th International Symposium on Healthy Aging, Young Investigator Award (Poster Category) Supported by Sun Chieh Yeh Heart Foundation, Research Center of Heart, Brain, Hormone & Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2018.

Chen H., Analgesic Effect of Sinew Acupuncture for Soft Tissue Injuries: A Prospective Observational Study, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Chen H., GUAN B., Chen X., Chen X., Li C., Qiu J., Yang D., Liu K., Qi S. and Shen J., Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway, Translational Stroke Research. Springer US, 2017.

Chen H., GUAN B. and Shen J., Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO-MMP9 pathway, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 第十屆龐鼎元國際中醫藥研討會, 2017, 102.

Chen H. and Shen J., Glycyrrhizin Attenuated Hemorrhagic Transformation and Improved Neurological Outcomes in Ischemic Stroke with Delayed t-PA Treatment, Possibly through Inhibiting the Interaction of Peroxynitrite and HMGB1 Signaling Pathways, 13th International Symposium on Healthy Aging. 2018.

Chen H., NING Z., LAM W.L., ZHAO Y., Lun W.M., Ng B.F.L., Ziea E.T.C. and Lao L., How to design a control in acupuncture randomized controlled trials, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Chen H. and Shen J., One-compound-multi-target: combination of natural compound with delayed tissue plasminogen activator for ischemic stroke treatment, 一个单体多个靶点：天然化合物与组织纤维蛋白溶酶原激活剂（t-PA）联用应用于急性脑卒中的展望, 中藥實驗藥理分會第十三次學術會議, 2017, 148.

Chen H. and Shen J., Peroxynitrite is an important target mediating hemorrhagic transformation induced by delayed tissue plasminogen activator (t-PA) treatment in ischemic stroke: potential application of natural compound baicalin , 中藥實驗藥理分會第十三次會議, 2017, 147.

Chen H. and Shen J., Poster Presentation Award, 中华中医药学会中药实验药理分会, 2017.

Chen H., Chen X., LI W. and Shen J., Targeting RNS/caveolin-1/MMP signaling cascades to protect against cerebral ischemia-reperfusion injuries: potential application for drug discovery, Acta Pharmacologica Sinica. 2018.

Chen X., Zhou B., Yan T., Wu H., Feng J., Chen H., GAO C., Peng T., Yang D. and Shen J., Peroxynitrite enhances self-renewal, proliferation and neuronal differentiation of neural stem/progenitor cells through activating HIF-1α and Wnt/β-catenin signaling pathway, Free Radical Biology and Medicine. 2018, 117: 158-167.

Cheng H.C., Mak H.C. and Chen H., The effectiveness and safety of Chinese Medicine on diabetic gastroparesis: a systematic and meta-analysis, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Lam W.L., Yeung W.F., Wong M.K., Cheung C.W., Chan K.K.L., Ngan H.Y.S., Wong C.K.H., Chen H. and Lao L., Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial, Trials. 2018, 19: 8.

Lee E., Xie Y., Chen H. and Meng W., Systematic Review of Chinese Medicine for Ovarian Endometriosis, International Journal of Pharmacognosy and Chinese Medicine. 2017, 1.

Lee P.Y. and Chen H., A systematic review of bloodletting therapy on patient with adhesive capsulitis, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Liu Z., Huang X.R., Chen H., Fung E., Liu J. and Lan H.Y., Deletion of Angiotensin-Converting Enzyme-2 Promotes Hypertensive Nephropathy by Targeting Smad7 for Ubiquitin DegradationNovelty and Significance, Hypertension. 2017, 70: 822-830.

Mak K.H., Cheng H.C. and Chen H., The effectiveness and safety of Chinese Medicine on diabetic nephropathy: a systematic review and meta-analysis, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Shen J., GUAN B., ZHAO L., DU Q. and Chen H., Network pharmacology study for traditional Chinese Medicine formula: treatment of ischemic stroke and osteoporosis with Kidney and Qi tonifying and blood-activating formula, 补肾益气活血方对脑卒中和骨质疏松症异病同治的药效观察及共同信号通路的网络药理学探索, 中医方证代谢组学研究进展(2017年卷), 2017.

Shen J., Chen H. and FENG J., Peroxynitrite could be a critical therapeutic target for preventing hemorrhagic transformation and poor outcome in ischemia-reperfused rat brains with delayed thrombolysis, 7th Global Experts Meeting on NEUROPHARMACOLOGY. 2017, 3: 66.

Song J., Sun L.Z., Zhen X.Y., Zhao Y., Zheng Y., Lao L., Chen H., Pei X., LU Y.H., Huang F.X. and Zhou L.Q., Discuss on Unity of Exopathy and Endopathy, 論外感與內傷的統一性, Journal of New Chinese Medicine. 新中醫, 2017, 49: 174-177.

Ying J., Zhou M.J., Chen H., Chen L., Zhang L., Ji J., Yu C. and Zhang Z., Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial, Chinese Journal of Integrative Medicine. 2018.

You Y., Lan H., Cheng Y. and Chen H., A Novel Small Molecule from Ganoderma lucidum Attenuates Renal Fibrosis in Obstructive Nephropathy, The 2nd Annual Conference of the Special Committee of Research on Safety of Clinical Usage of Drugs WFCMS (World Federation of Chinese Medicine Societies). 2017.

You Y., WU W., Lan H., Cheng Y. and Chen H., A novel small molecule from Ganoderma Lucidum attenuates renal fibrosis in mouse UUO model, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Researcher : Chen H

List of Research Outputs

Chen H. and Shen J., Poster Presentation Award, 中华中医药学会中药实验药理分会, 2017.

Lee E., Xie Y., Chen H. and Meng W., Systematic Review of Chinese Medicine for Ovarian Endometriosis, International Journal of Pharmacognosy and Chinese Medicine. 2017, 1.

Lee P.Y. and Chen H., A systematic review of bloodletting therapy on patient with adhesive capsulitis, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Researcher : Chen J

Project Title:	The development of multimedia tearching and learning system in TCM -prescrption subject
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:	07/2011

Project Title:	Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):	Chen J, Guan X, Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	01/2012

Project Title:	Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A (ITS/073/11FP)
Investigator(s):	Chen J, Guan X, Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	01/2012

Project Title:	Ninth AACR-Japanese Cancer Association Joint Conference: Breakthroughs in Basic and Translational Cancer Research; Isoliquiritigenin promotes breast cancer chemosensitivity by limiting cancer stem cells targeting aberrant β-catenin signaling
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	02/2013

Project Title:	Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):	Chen J, Guan X, Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	07/2013

Project Title:	Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):	Chen J, Guan X, Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	07/2013

Project Title:	Development of tea bag YH0618, an herbal dietary supplement against chemotherapy-induced toxicity
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Matching Grant for Joint Research
Start Date:	08/2015

Project Title:	Development of Tea Bag YH0618, an Herbal Dietary Supplement against Chemotherapy-induced Toxicity
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	09/2015

Project Title:	Development of Tea Bag YH0618, an Herbal Dietary Supplement against Chemotherapy-induced Toxicity
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	10/2015

Project Title:	The inhibitory effect of Suberect Spatholobus on the migration of breast cancer via Wnt/β-catenin pathway induced by miRNA
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	National Natural Science Foundation of China (NSFC) - General Program
Start Date:	01/2016

Project Title:	Reduction of chemotherapy-induced toxicity in cancer patients after chemotherapy using a medical food YH0618: a pilot controlled trial
Investigator(s):	Chen J, He Y, Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Translational and Applied Research
Start Date:	03/2017

Project Title:	A safety issue of Traditional Chinese Medicine: Whether it is appropriate to use a famous Chinese medicine Radix Angelicae Sinensis (Danggui) on women with breast cancer
Investigator(s):	Chen J, Tang H, Jia L
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	05/2017

Project Title:	Elucidating critical role of GPR49 in mediating cancer dormancy and activation of breast cancer stem cells by enhancing Wnt signalling
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:	07/2017
Completion Date:	11/2017

Project Title:	22nd International Conference and Expo.; Effect of YH0618 soup on chemotherapy-induced toxicity in cancer patients: study protocol for a randomized controlled trial
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	09/2017

Project Title:	Preclinical study of a novel drug (Spatholobus Suberectus Dunn's extract) by chemosensitizing the paclitaxel on treating triple-negative breast cancer.
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Translational and Applied Research
Start Date:	06/2018

List of Research Outputs

Chen J., Angelica sinenesis promotes activity of human breast cancer stem cells through estrogen receptor α, 2018.

Chen J., Angelica sinenesis promotes activity of human breast cancer stem cells through estrogen receptor α, 2017.

Chen J., UPLC法同時測定黑豆甘草湯中8個指標成分, 2018.

PENG F. and Chen J., Isoliquiritigenin modulates miR- 374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis, Sci report, 2017, 14.

PENG F., Tang H., Liu P., Shen J., Guan X., Xie X., Gao J., Jia L., Chen J. and Peng C., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis., Scientific Reports . 2017, 7(1):9022.

SUN Y. and Chen J., The theory development of traditional Chinese medicine constitution: a review, Journal of Traditional Chinese Medical Sciences. 2018, 5: 16-28.

Tang H., PENG F., Huang X., Xie X., Chen B., Shen J., GAO F., YOU J. and Chen J., Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-β-catenin signaling in breast cancer., Curr Cancer Drug Targets. . 2017, 2017.

zhao J., fu C., GAO F. and Chen J., 中药袋泡茶剂的现代定位与关键问题分析, 中药材, 2017, Volume 40.

zheng X., Chen J., Xie T., Xia Z. and Loo T.Y., Relationship between dietary patterns of Chinese medicine and the risk of breast cancer in Chinese women in Hong Kong: an epidemiological studysurvey, Chinese medicine. 2017.

Researcher : Chen K

List of Research Outputs

PENG F., Tang H., Peng C. and Chen K., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis, explore . 2017.

Researcher : Chen X

List of Research Outputs

Researcher : Cheng C

List of Research Outputs

Cheng C., Chen J., Tan H.Y.H., Wang N., Chen Z. and Feng Y., Scutellaria baicalensis and Cancer Treatment: Recent Progress and Perspectives in Biomedical and Clinical Studies , The American Journal of Chinese Medicine. 2018, 1-30.

Tan H.Y.H., Wang N., LI S., HONG M., GUO W., Man K., Cheng C., Chen Z. and Feng Y., Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs β-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma., Cellular Physiology and Biochemistry. 2018, 47: 1819-1834.

Researcher : Cheung F

List of Research Outputs

Huang J., Cheung F., Tan H.Y.H., HONG M., Wang N., Yang J., Feng Y. and Zheng Q., Identification of the active compounds and significant pathways of yinchenhao decoction based on network pharmacology, Molecular Medicine Reports. 2017.

Huang J., LI L., Cheung F., Wang N., Li Y., Fan Z., Yin F., Yang J., Gao R., He Y. and Feng Y., Network Pharmacology-Based Approach to Investigate the Analgesic Efficacy and Molecular Targets of Xuangui Dropping Pill for Treating Primary Dysmenorrhea, Evidence-Based Complementary and Alternative Medicine. 2017, 2017: 1-12.

LI S., Tan H.Y.H., Wang N., Cheung F., HONG M. and Feng Y., The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases., Oxidative medicine and cellular longivety. 2018, 4.

Researcher : DU Q

List of Research Outputs

Gao C., Du Q., LI W., Deng R., Wang Q., Xu A. and Shen J., Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression, Molecular Neurobiology. 2018.

Shen J., GUAN B., ZHAO L., DU Q. and Chen H., Network pharmacology study for traditional Chinese Medicine formula: treatment of ischemic stroke and osteoporosis with Kidney and Qi tonifying and blood-activating formula, 补肾益气活血方对脑卒中和骨质疏松症异病同治的药效观察及共同信号通路的网络药理学探索, 中医方证代谢组学研究进展(2017年卷), 2017.

Researcher : Deng R

Project Title:	Exploring effects of Astragaloside IV, an active component of Astragalus, as an adjunct therapy with radiation therapy and/or chemotherapy to promote haematopoiesis in cancer treatment
Investigator(s):	Deng R, Shen J, Chan GCF
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	08/2017

List of Research Outputs

Deng R., Zhou B., Guan B., Chan G.C.F. and Shen J., Marine algae extract attenuated osteoporosis in OVX mice, enhanced osteogenesis on human mesenchymal stem cells and promoted OPG expression, In: Vincenzo Fogliano, Journal of Functional Foods. ELSEVIER, 2017, 40: 229-237.

Gao C., Du Q., LI W., Deng R., Wang Q., Xu A. and Shen J., Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression, Molecular Neurobiology. 2018.

Researcher : Du Q

List of Research Outputs

Researcher : FENG J

List of Research Outputs

Chen X., Zhou B., Yan T., Wu H., Feng J., Chen H., GAO C., Peng T., Yang D. and Shen J., Peroxynitrite enhances self-renewal, proliferation and neuronal differentiation of neural stem/progenitor cells through activating HIF-1α and Wnt/β-catenin signaling pathway, Free Radical Biology and Medicine. 2018, 117: 158-167.

Shen J., Chen H. and FENG J., Peroxynitrite could be a critical therapeutic target for preventing hemorrhagic transformation and poor outcome in ischemia-reperfused rat brains with delayed thrombolysis, 7th Global Experts Meeting on NEUROPHARMACOLOGY. 2017, 3: 66.

Researcher : Feng J

List of Research Outputs

Researcher : Feng Y

Project Title:	Identification of the anti-tumour activity of a novel natural product derived-Histone Deacetylase inhibitor ZG01 on human hepatocellular carcinoma
Investigator(s):	Feng Y, Wang N
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	04/2016
Completion Date:	03/2018

Project Title:	Inhibitory effect of geniposide on hepatocellular carcinoma: the role of Hiwi
Investigator(s):	Feng Y, Tsao GSW, Man K, Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	11/2016

Project Title:	Secondary Development of Classical Chinese Medicine Formula Huanglian Jiedu Decoction (HLJDD): HLJDD Reducing Chemotherapy-induced Diarrhoea and Improving Chemotherapy Response
Investigator(s):	Feng Y, Wang N, Cheung F
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Support Programme (Tier 2)
Start Date:	03/2017

Project Title:	HKU Overseas Fellowship Awards 2017-18
Investigator(s):	Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	HKU Overseas Fellowship Awards
Start Date:	06/2017

Project Title:	Metabolomic study to reveal the mechanism underlying the anti-tumor activity of Chinese Medicine formula Zuo-Jin Wan on human hepatocellular carcinoma (HCC)
Investigator(s):	Feng Y, Wang N
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	06/2017

Project Title:	Inhibitory effect of natural compound fangchinoline from Stephania tetrandra S. Moore on human liver cancer stem cells
Investigator(s):	Feng Y, Guan X, Wang N
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:	07/2017
Completion Date:	11/2017

Project Title:	3rd Zebrafish for Personalized/Precision Medicine Conference; Drug discovery from Chinese medicines: the past and prospect
Investigator(s):	Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	09/2017
Completion Date:	09/2017

List of Research Outputs

CHENG Y., Feng Y., Xia Z., Li X.C. and Rong J., ω-Alkynyl arachidonic acid promotes anti-inflammatory macrophage M2 polarization against acute myocardial infarction via regulating the cross-talk between PKM2, HIF-1α and iNOS, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2017, 1862: 1595-1605.

Chen J.Y., Chin W.Y., Chan L.K., Tiwari A.F.Y., Wong J.Y.H., Worsley A.J., Feng Y., Sham M.H., Tsang J.P.Y. and Lau W.C.S., Free Paper Presentation - Poster Audience Award, Asian Medical Education Association. 2017.

Chen J.Y., Chin W.Y., Chan L.K., Tiwari A., Worsley A.J., Feng Y., Sham M.H., Tsang J.P.Y. and Lau W.C.S., Stress and its impact on learning: a snapshot of first year health sciences students in the Li Ka Shing Faculty of Medicine, Ninth Asia Medical Education Association Symposium cum Frontiers in Medical and Health Sciences Education . 2017.

Cheng C., Chen J., Tan H.Y.H., Wang N., Chen Z. and Feng Y., Scutellaria baicalensis and Cancer Treatment: Recent Progress and Perspectives in Biomedical and Clinical Studies , The American Journal of Chinese Medicine. 2018, 1-30.

Feng Y., Hong Kong Chinese Medical Journal, In: 陈抗生, 邓春, 温桂荣, 赵中正, 冯奕斌, 吴俊来, 王如跃, 黄约爱,, Hong Kong Chinese Medical Journal. 香港中医杂志, Hong Kong, 香港中医杂志出版社, 2018.

GUO W., Tan H.Y.H., Wang N., Wang X. and Feng Y., Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation, Cancer management and research. 2018, 10: 715-734.

HONG M., Zhang Y., LI S., Tan H.Y.H., Wang N., Mu S., Hao X. and Feng Y., A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae, Molecules. 2017, 22: 1617.

Huang J., Cheung F., Tan H.Y.H., HONG M., Wang N., Yang J., Feng Y. and Zheng Q., Identification of the active compounds and significant pathways of yinchenhao decoction based on network pharmacology, Molecular Medicine Reports. 2017.

Huang J., LI L., Cheung F., Wang N., Li Y., Fan Z., Yin F., Yang J., Gao R., He Y. and Feng Y., Network Pharmacology-Based Approach to Investigate the Analgesic Efficacy and Molecular Targets of Xuangui Dropping Pill for Treating Primary Dysmenorrhea, Evidence-Based Complementary and Alternative Medicine. 2017, 2017: 1-12.

LI S., Wang N., HONG M., Tan H.Y.H., Pan G. and Feng Y., Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components, Molecules. 2018, 23: 352.

LI S., Tan H.Y.H., Wang N., Cheung F., HONG M. and Feng Y., The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases., Oxidative medicine and cellular longivety. 2018, 4.

Tan H.Y.H., Wang N., Takahashi M. and Feng Y., NYG, A Novel Pigmented Fraction of Saw Palmetto, Suppresses Tumour Angiogenesis and Progression of Human Hepatocellular Carinoma, 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Tan H.Y.H., Wang N., LI S., HONG M., GUO W., Man K., Cheng C., Chen Z. and Feng Y., Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs β-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma., Cellular Physiology and Biochemistry. 2018, 47: 1819-1834.

Tan H.Y.H., Wang N. and Feng Y., Targeting tumour associated macrophages by traditional Chinese medicines , The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Wang N., Tan H.Y.H., LI S. and Feng Y., Atg9b Deficiency Suppresses Autophagy and Potentiates Endoplasmic Reticulum Stress-Associated Hepatocyte Apoptosis in Hepatocarcinogenesis, Theranostics. 2017, 7: 2325-2338.

Wang N., Tan H.Y.H., Chan Y.T., GUO W., LI S. and Feng Y., Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde, Oncotarget. 2017, 8.

Wang N., Tan H.Y.H., LI S., XU Y., GUO W. and Feng Y., Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant, Oxidative Medicine and Cellular Longevity. 2017, 2017: 1-13.

ZHANG C., Wang N., Tan H.Y.H., GUO W., LI S. and Feng Y., Targeting VEGF/VEGFRs Pathway in the Antiangiogenic Treatment of Human Cancers by Traditional Chinese Medicine, Integrative Cancer Therapies. 2018, 17: 582-601.

Zhang C., XU Y., Tan H.Y.H., LI S., Wang N., Zhang Y. and Feng Y., Neuroprotective effect of He-Ying-Qing-Re formula on retinal ganglion cell in diabetic retinopathy, Journal of Ethnopharmacology. 2018, 214: 179-189.

Researcher : GAO C

List of Research Outputs

Chen X., Zhou B., Yan T., Wu H., Feng J., Chen H., GAO C., Peng T., Yang D. and Shen J., Peroxynitrite enhances self-renewal, proliferation and neuronal differentiation of neural stem/progenitor cells through activating HIF-1α and Wnt/β-catenin signaling pathway, Free Radical Biology and Medicine. 2018, 117: 158-167.

Gao C., Du Q., LI W., Deng R., Wang Q., Xu A. and Shen J., Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression, Molecular Neurobiology. 2018.

Researcher : GAO F

List of Research Outputs

Tang H., PENG F., Huang X., Xie X., Chen B., Shen J., GAO F., YOU J. and Chen J., Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-β-catenin signaling in breast cancer., Curr Cancer Drug Targets. . 2017, 2017.

zhao J., fu C., GAO F. and Chen J., 中药袋泡茶剂的现代定位与关键问题分析, 中药材, 2017, Volume 40.

Researcher : GUAN B

List of Research Outputs

Chen H., GUAN B., Chen X., Chen X., Li C., Qiu J., Yang D., Liu K., Qi S. and Shen J., Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway, Translational Stroke Research. Springer US, 2017.

Chen H., GUAN B. and Shen J., Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO-MMP9 pathway, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 第十屆龐鼎元國際中醫藥研討會, 2017, 102.

Deng R., Zhou B., Guan B., Chan G.C.F. and Shen J., Marine algae extract attenuated osteoporosis in OVX mice, enhanced osteogenesis on human mesenchymal stem cells and promoted OPG expression, In: Vincenzo Fogliano, Journal of Functional Foods. ELSEVIER, 2017, 40: 229-237.

Shen J., GUAN B., ZHAO L., DU Q. and Chen H., Network pharmacology study for traditional Chinese Medicine formula: treatment of ischemic stroke and osteoporosis with Kidney and Qi tonifying and blood-activating formula, 补肾益气活血方对脑卒中和骨质疏松症异病同治的药效观察及共同信号通路的网络药理学探索, 中医方证代谢组学研究进展(2017年卷), 2017.

Researcher : GUO W

List of Research Outputs

GUO W., Tan H.Y.H., Wang N., Wang X. and Feng Y., Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation, Cancer management and research. 2018, 10: 715-734.

Tan H.Y.H., Wang N., LI S., HONG M., GUO W., Man K., Cheng C., Chen Z. and Feng Y., Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs β-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma., Cellular Physiology and Biochemistry. 2018, 47: 1819-1834.

Wang N., Tan H.Y.H., Chan Y.T., GUO W., LI S. and Feng Y., Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde, Oncotarget. 2017, 8.

Wang N., Tan H.Y.H., LI S., XU Y., GUO W. and Feng Y., Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant, Oxidative Medicine and Cellular Longevity. 2017, 2017: 1-13.

ZHANG C., Wang N., Tan H.Y.H., GUO W., LI S. and Feng Y., Targeting VEGF/VEGFRs Pathway in the Antiangiogenic Treatment of Human Cancers by Traditional Chinese Medicine, Integrative Cancer Therapies. 2018, 17: 582-601.

Researcher : Gao C

List of Research Outputs

Researcher : Guan B

List of Research Outputs

Researcher : HONG M

List of Research Outputs

HONG M., Zhang Y., LI S., Tan H.Y.H., Wang N., Mu S., Hao X. and Feng Y., A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae, Molecules. 2017, 22: 1617.

Huang J., Cheung F., Tan H.Y.H., HONG M., Wang N., Yang J., Feng Y. and Zheng Q., Identification of the active compounds and significant pathways of yinchenhao decoction based on network pharmacology, Molecular Medicine Reports. 2017.

LI S., Wang N., HONG M., Tan H.Y.H., Pan G. and Feng Y., Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components, Molecules. 2018, 23: 352.

LI S., Tan H.Y.H., Wang N., Cheung F., HONG M. and Feng Y., The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases., Oxidative medicine and cellular longivety. 2018, 4.

Tan H.Y.H., Wang N., LI S., HONG M., GUO W., Man K., Cheng C., Chen Z. and Feng Y., Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs β-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma., Cellular Physiology and Biochemistry. 2018, 47: 1819-1834.

Researcher : Hao D

List of Research Outputs

Hao D., 常見膝關節運動損傷診治, 香港中醫骨傷學會專題講座, 2018.

Hao D., 常見膝關節運動損傷診治, 香港中醫骨傷科學術年會2017暨34周年會慶——膝關節損傷及相關病變, 2017.

Researcher : Hu KY

Project Title:	The 6th World Congress of Chinese Medicine 2009 The International Spread Characteristics of Traditional Chinese Medicine
Investigator(s):	Hu KY
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	12/2009

Researcher : Huang J

List of Research Outputs

Huang J., LI L., Cheung F., Wang N., Li Y., Fan Z., Yin F., Yang J., Gao R., He Y. and Feng Y., Network Pharmacology-Based Approach to Investigate the Analgesic Efficacy and Molecular Targets of Xuangui Dropping Pill for Treating Primary Dysmenorrhea, Evidence-Based Complementary and Alternative Medicine. 2017, 2017: 1-12.

Researcher : LAM KH

List of Research Outputs

CHEN X., LAM K.H., CHEN Q., Leung G.P.H., Tang S.C.W., Sze C.W.S., Xiao J., Feng F., Wang Y., Zhang Y. and Zhang Z., Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats, Food and Chemical Toxicology. 2017, 110: 49-61.

Researcher : LAM WL

List of Research Outputs

Chen H., NING Z., LAM W.L., ZHAO Y., Lun W.M., Ng B.F.L., Ziea E.T.C. and Lao L., How to design a control in acupuncture randomized controlled trials, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Lam W.L., Yeung W.F., Wong M.K., Cheung C.W., Chan K.K.L., Ngan H.Y.S., Wong C.K.H., Chen H. and Lao L., Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial, Trials. 2018, 19: 8.

Researcher : LI L

List of Research Outputs

CHAN W.C.C., Lo K.C. and Li L., Acupressure for Frail Older Adults under Residential Care – a randomized controlled trial, 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Guangzhou, Chian, 2017.

Huang J., LI L., Cheung F., Wang N., Li Y., Fan Z., Yin F., Yang J., Gao R., He Y. and Feng Y., Network Pharmacology-Based Approach to Investigate the Analgesic Efficacy and Molecular Targets of Xuangui Dropping Pill for Treating Primary Dysmenorrhea, Evidence-Based Complementary and Alternative Medicine. 2017, 2017: 1-12.

Li L., An Analysis of the Tonic Drugs in Shen Nong 's Classic of Materia Medica, 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Guangzhou, Chian, 2017.

Li L., On the Positioning of the Scalp Needle Stimulation Areas, Traditional Chinese Medicine. 2017, 6(4): 183-185.

Li L., Taiji Theory and Health Preservation, Chinese Medical Culture. 2017, Volume 2 (Winter Edition): 38-44.

Li L., Taiji Theory and Health Preserving, 14th China-Shanghai International Symposium on Qigong Science and First Shanghai Taiji Health Symposium. Shanghai, China., 2017.

Liu C.H.I.E.N.P.A.N.G., Chang Y.A.C.H.I.N.G., Lo K.C. and Li L., Clinical Study of Infantile Massage Combined with Acupuncture for Autism, New Chinese Medicine. 2017, 49(8): 122-125.

Tse W.A.I. .H.O. and Li L., The Study of JinZhenFu, 10th Taipei Traditional Chinese Medicine International Forum 2018. Taipei, Taiwan.

Wang J.I.N.G., Li L. and Huang A.N., Ancient Literature on Acupuncture and Moxibustion (Textbook for National Higher Medical University and College), 針灸古代文獻, Shanghai, Shanghai Scientific & Technical Publishers, 2018, 229.

Wong Y.I.U.L.I.N., Lo K.C. and Li L., Clinical Research Progress of Aacupuncture and Moxibustion Therapy in the Treatment of Rheumatoid Arthritis, Global Traditional Chinese Medicine. 2017, 10(7): 793-798.

Researcher : LI S

List of Research Outputs

HONG M., Zhang Y., LI S., Tan H.Y.H., Wang N., Mu S., Hao X. and Feng Y., A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae, Molecules. 2017, 22: 1617.

LI S., Wang N., HONG M., Tan H.Y.H., Pan G. and Feng Y., Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components, Molecules. 2018, 23: 352.

LI S., Tan H.Y.H., Wang N., Cheung F., HONG M. and Feng Y., The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases., Oxidative medicine and cellular longivety. 2018, 4.

Tan H.Y.H., Wang N., LI S., HONG M., GUO W., Man K., Cheng C., Chen Z. and Feng Y., Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs β-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma., Cellular Physiology and Biochemistry. 2018, 47: 1819-1834.

Wang N., Tan H.Y.H., LI S. and Feng Y., Atg9b Deficiency Suppresses Autophagy and Potentiates Endoplasmic Reticulum Stress-Associated Hepatocyte Apoptosis in Hepatocarcinogenesis, Theranostics. 2017, 7: 2325-2338.

Wang N., Tan H.Y.H., Chan Y.T., GUO W., LI S. and Feng Y., Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde, Oncotarget. 2017, 8.

Wang N., Tan H.Y.H., LI S., XU Y., GUO W. and Feng Y., Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant, Oxidative Medicine and Cellular Longevity. 2017, 2017: 1-13.

ZHANG C., Wang N., Tan H.Y.H., GUO W., LI S. and Feng Y., Targeting VEGF/VEGFRs Pathway in the Antiangiogenic Treatment of Human Cancers by Traditional Chinese Medicine, Integrative Cancer Therapies. 2018, 17: 582-601.

Zhang C., XU Y., Tan H.Y.H., LI S., Wang N., Zhang Y. and Feng Y., Neuroprotective effect of He-Ying-Qing-Re formula on retinal ganglion cell in diabetic retinopathy, Journal of Ethnopharmacology. 2018, 214: 179-189.

Researcher : LI W

List of Research Outputs

Chen H., Chen X., LI W. and Shen J., Targeting RNS/caveolin-1/MMP signaling cascades to protect against cerebral ischemia-reperfusion injuries: potential application for drug discovery, Acta Pharmacologica Sinica. 2018.

Gao C., Du Q., LI W., Deng R., Wang Q., Xu A. and Shen J., Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression, Molecular Neurobiology. 2018.

Researcher : LUO D

List of Research Outputs

LUO D., Guo Y., CHENG Y., Zhao J., Wang Y. and Rong J., Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways, Aging. 2017.

Researcher : Lam WL

List of Research Outputs

Researcher : Lao L

Project Title:	2014 International Research Congress on Integrative Medicine and Health; Acupuncture and Complementary Medicine in Pain Management/Acupuncture and Mindfulness-Based Stress Reduction among Female Child Abuse Survivors: A Randomized Waitlist-Controlled Pilot Study
Investigator(s):	Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	05/2014

Project Title:	Distal acupoint stimulation sensitizes peripheral mast cells to osteoarthritis synovium via adenosine signaling
Investigator(s):	Lao L, Chen H, Yeung YF
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	06/2015
Completion Date:	09/2017

Project Title:	Combined Electroacupuncture and Auricular Acupuncture for Postoperative Pain after Abdominal Surgery for Gynecological Diseases: A Randomized Sham-controlled Trial
Investigator(s):	Lao L, Ngan HYS, Chen H, Cheung CW, Yeung WF, Chan KKL, Wong CKH, Jiang F
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	07/2016

Project Title:	A randomized, wait-list controlled trial of self-administered acupressure for symptom management among Chinese family caregivers with caregiver stress
Investigator(s):	Lao L, Lum TYS, Wang XMA, Cheung ST, Zhang Z, Tiwari AFY
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	07/2016

Project Title:	2018 International Congress on Integrative Medicine and Health; A double-blind, randomized, two-dose trial of Chinese medicine, Tumor-Shrinking Decoction (TSD), in patients with symptomatic uterine fibroids
Investigator(s):	Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	05/2018
Completion Date:	05/2018

Project Title:	Development of a Novel Auriculotherapy Device for Pain Management
Investigator(s):	Lao L, Cheung CW, Chen H, Yang C
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Translational and Applied Research
Start Date:	06/2018

List of Research Outputs

Au K.Y., Chen H., Lam W.C., Chong C.O., Lau A., Vardhanabhuti V., Mak K.C., Jiang F., Lam W.Y., Wu F.M., Chan H.N., Ng Y.W., Ng B.F.L., Ziea E.T. and Lao L., Sinew acupuncture for knee osteoarthritis: study protocol for a randomized sham-controlled trial, BMC Complementary and Alternative Medicine. 2018, 18.

CHEN X., Leung G.P.H., Zhang Z., Xiao J.B., Lao L., Feng F., Mak J.C.W., Wang Y., Sze C.W.S. and Zhang Y., Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil, Food and Chemical Toxicology. 2017, 107: 248-260.

Chen H., NING Z., LAM W.L., ZHAO Y., Lun W.M., Ng B.F.L., Ziea E.T.C. and Lao L., How to design a control in acupuncture randomized controlled trials, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Lam W.L., Yeung W.F., Wong M.K., Cheung C.W., Chan K.K.L., Ngan H.Y.S., Wong C.K.H., Chen H. and Lao L., Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial, Trials. 2018, 19: 8.

Mu J.L., Furlan A.D., Lam W.Y., Hsu M.Y., NING Z. and Lao L., Acupuncture for chronic non-specific low back pain: a systematic review and meta-analysis., In: Jinglan MU, The 16th Meeting of Consortium for Globalization of Chinese Medicine. Guang Zhou, The 16th CGCM conference, 2017, 25.

Rong J. and Lao L., Unexpected antidepressant and analgesic activities of Chinese medicine puerarin and its molecular targets, 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). 2017.

Song J., Sun L.Z., Zhen X.Y., Zhao Y., Zheng Y., Lao L., Chen H., Pei X., LU Y.H., Huang F.X. and Zhou L.Q., Discuss on Unity of Exopathy and Endopathy, 論外感與內傷的統一性, Journal of New Chinese Medicine. 新中醫, 2017, 49: 174-177.

Yang C., Du .., Sun .., Long .., Li .., Shen .., Wu .., Lao L. and Liang .., Acupuncture for stable angina pectoris: a systematic review protocol, BMJ Open. the BMJ Publishing Group Ltd., 2018, 8: e019798.

Yeung W.F., Ho F.Y., Chung K.F., Zhang Z., Yu B.Y., Suen L.K., Chan L.Y., Chen H.Y., Ho L.M. and Lao L., Self-administered acupressure for insomnia disorder: a pilot randomized controlled trial, Journal of Sleep Research. 2018, 27: 220-231.

Zhao J., Rong J. and Lao L., Unexpected Antidepressant and Analgesic Activities of Chinese Medicine Puerarin and its Molecular Targets, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Zhao J., Lao L. and Rong J., Unexpected antidepressant and analgesic activities of Chinese medicine puerarin and its molecular targets, The 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), August 18 - 20, 2017, Guangzhou, China. 2017.

Researcher : Li L

Project Title:	Efficacy Observation on Tian Jiu Therapy for Asthma
Investigator(s):	Li L, Lao L, Cherny SS
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	04/2015

Project Title:	Effects of Massage methodology on the constipaion problem among the pre-school aged children with behavioral problem in subvented services in Yan Chai Hospital Social Services Department
Investigator(s):	Li L, Lo KC, Chau PH
Department:	School of Chinese Medicine
Source(s) of Funding:	Yan Chai Hospital Board
Start Date:	09/2017

List of Research Outputs

Li L., An Analysis of the Tonic Drugs in Shen Nong 's Classic of Materia Medica, 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Guangzhou, Chian, 2017.

Li L., On the Positioning of the Scalp Needle Stimulation Areas, Traditional Chinese Medicine. 2017, 6(4): 183-185.

Li L., Taiji Theory and Health Preservation, Chinese Medical Culture. 2017, Volume 2 (Winter Edition): 38-44.

Li L., Taiji Theory and Health Preserving, 14th China-Shanghai International Symposium on Qigong Science and First Shanghai Taiji Health Symposium. Shanghai, China., 2017.

Liu C.H.I.E.N.P.A.N.G., Chang Y.A.C.H.I.N.G., Lo K.C. and Li L., Clinical Study of Infantile Massage Combined with Acupuncture for Autism, New Chinese Medicine. 2017, 49(8): 122-125.

Tse W.A.I. .H.O. and Li L., The Study of JinZhenFu, 10th Taipei Traditional Chinese Medicine International Forum 2018. Taipei, Taiwan.

Researcher : Liu C

Project Title:	6th Annual Rocky Mountain Bioinformatics Conference CADEG, a Set of Software Tools for High Resolution Identification of Potential Chromosomal Abnormalities
Investigator(s):	Liu C
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	12/2008

Researcher : Liu P

List of Research Outputs

PENG F., Tang H., Liu P., Shen J., Guan X., Xie X., Gao J., Jia L., Chen J. and Peng C., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis., Scientific Reports . 2017, 7(1):9022.

Researcher : Lo KC

List of Research Outputs

CHAN W.C.C., Lo K.C. and Li L., Acupressure for Frail Older Adults under Residential Care – a randomized controlled trial, 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Guangzhou, Chian, 2017.

Liu C.H.I.E.N.P.A.N.G., Chang Y.A.C.H.I.N.G., Lo K.C. and Li L., Clinical Study of Infantile Massage Combined with Acupuncture for Autism, New Chinese Medicine. 2017, 49(8): 122-125.

Wong Y.I.U.L.I.N., Lo K.C. and Li L., Clinical Research Progress of Aacupuncture and Moxibustion Therapy in the Treatment of Rheumatoid Arthritis, Global Traditional Chinese Medicine. 2017, 10(7): 793-798.

Researcher : Loo TY

List of Research Outputs

zheng X., Chen J., Xie T., Xia Z. and Loo T.Y., Relationship between dietary patterns of Chinese medicine and the risk of breast cancer in Chinese women in Hong Kong: an epidemiological studysurvey, Chinese medicine. 2017.

Researcher : Meng W

Project Title:	A double-blinded, randomized, two-dose trial of Tumor-shrinking Decoction (TSD), a Chinese medicine preparation in patients with symptomatic uterine fibroids
Investigator(s):	Meng W, Rong J, Su J, Chen J, Lam PY, Zhang Z, Ng EHY, Zhang Y, Yeung WF, Lee EYP
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	05/2014
Completion Date:	07/2017

List of Research Outputs

Lee E., Xie Y., Chen H. and Meng W., Systematic Review of Chinese Medicine for Ovarian Endometriosis, International Journal of Pharmacognosy and Chinese Medicine. 2017, 1.

Researcher : Mu JL

Project Title:	5th Annual European Conference on Clinical and Translational Sciences (EUSTM-2017); Acupuncture for chronic non-specific low back pain: a systematic review and meta-analysis.
Investigator(s):	Mu JL
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	10/2017
Completion Date:	10/2017

List of Research Outputs

Mu J.L., Furlan A.D., Lam W.Y., Hsu M.Y., NING Z. and Lao L., Acupuncture for chronic non-specific low back pain: a systematic review and meta-analysis., In: Jinglan MU, The 16th Meeting of Consortium for Globalization of Chinese Medicine. Guang Zhou, The 16th CGCM conference, 2017, 25.

Researcher : NING Z

List of Research Outputs

Chen H., NING Z., LAM W.L., ZHAO Y., Lun W.M., Ng B.F.L., Ziea E.T.C. and Lao L., How to design a control in acupuncture randomized controlled trials, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Mu J.L., Furlan A.D., Lam W.Y., Hsu M.Y., NING Z. and Lao L., Acupuncture for chronic non-specific low back pain: a systematic review and meta-analysis., In: Jinglan MU, The 16th Meeting of Consortium for Globalization of Chinese Medicine. Guang Zhou, The 16th CGCM conference, 2017, 25.

Researcher : PENG F

List of Research Outputs

PENG F. and Chen J., Isoliquiritigenin modulates miR- 374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis, Sci report, 2017, 14.

PENG F., Tang H., Liu P., Shen J., Guan X., Xie X., Gao J., Jia L., Chen J. and Peng C., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis., Scientific Reports . 2017, 7(1):9022.

PENG F., Tang H., Peng C. and Chen K., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis, explore . 2017.

Tang H., PENG F., Huang X., Xie X., Chen B., Shen J., GAO F., YOU J. and Chen J., Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-β-catenin signaling in breast cancer., Curr Cancer Drug Targets. . 2017, 2017.

Researcher : Rong J

Project Title:	The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy
Investigator(s):	Rong J
Department:	LKS Medical Faculty
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	10/2006

Project Title:	Novel caffeic acid derivatives promote the phenotypic and functional switch of macrophages toward resolution of inflammation and cardiac regeneration after myocardial infarction
Investigator(s):	Rong J, Li XC
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	11/2015

Project Title:	ω-Alkynyl arachidonic acid induces anti-inflammatory M2 polarization of macrophages in acute myocardial infarction via regulating the cross-talk between PKM2, iNOS and HIF-1α
Investigator(s):	Rong J, Feng Y, Xia Z, Li XC
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2017

Project Title:	Chinese medicine celastrol ameliorates inflammation and metabolic dysfunction in adipose tissues via covalent modification of ER chaperone GRP78/BiP
Investigator(s):	Rong J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	03/2017
Completion Date:	03/2018

Project Title:	Plant-derived celastrol ameliorates metabolic dysfunctions, oxidative stress and inflammation in diet-induced obesity via disrupting the cross-talk between PKM2, HIF-1α and IL-1β
Investigator(s):	Rong J, Xia Z, Li XC, Wang Y
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2018

Project Title:	Chinese medicine celastrol inhibits atherosclerotic foam cell formation via reducing lipid accumulation and ameliorating ER stress in diet-induced obese mice
Investigator(s):	Rong J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	04/2018

List of Research Outputs

CHENG Y., Li X.C., Tse H.F. and Rong J., Gallic Acid-L-Leucine Conjugate Protects Mice against LPS-Induced Inflammation and Sepsis via Correcting Proinflammatory Lipid Mediator Profiles and Oxidative Stress, Oxidative Medicine and Cellular Longevity. 2018, 2018: 1-14.

CHENG Y. and Rong J., Macrophage Polarization as a Therapeutic Target in Myocardial Infarction, Current Drug Targets. 2017, 18.

CHENG Y. and Rong J., Prostaglandin 15-keto PGF2α skews macrophage M1/M2 polarization against myocardial ischemia reperfusion injury via covalent modification of glycolytic enzyme PKM2, The 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), August 18 - 20, 2017, Guangzhou, China. 2017.

CHENG Y., Feng Y., Xia Z., Li X.C. and Rong J., ω-Alkynyl arachidonic acid promotes anti-inflammatory macrophage M2 polarization against acute myocardial infarction via regulating the cross-talk between PKM2, HIF-1α and iNOS, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2017, 1862: 1595-1605.

LUO D., Guo Y., CHENG Y., Zhao J., Wang Y. and Rong J., Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways, Aging. 2017.

Rong J., A new anti-obesity mechanism by targeting macrophages, School of Pharmacy, Southwest University, 2018.05.26, Chongqing, China.. 2018.

Rong J., Chinese medicine celastrol ameliorates metabolic dysfunction, oxidative stress and inflammation in diet-induced obesity, 2018 (3rd) Natural Product Medicine Symposium & Hong Kong-Macao-Taiwan Forum, 2018.04.12-13, Shanghai, China.. 2018.

Rong J., Chinese medicine celastrol forms covalent conjugate with ER chaperone protein GRP78 against diet-induced obesity, 302 Military Hospital of China, 2018.05. 27, Beijing, China.. 2018.

Rong J., Discovery of the endogenous arachidonic acid metabolites against myocardial ischemia reperfusion injury, The 13th Meeting on Experimental Chinese Medicine Pharmacology, The Chinese Medicine Association, Sep 21 - 23, 2017, Ningbo, Zhejiang, China. 2017.

Rong J., Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways, The 3rd ISANH Middle East World Congress & Amman Antioxidants 2018 2018.05.02-03, Amman, Jordan.. 2018.

Rong J., Novel compounds helps resolution of inflammation and tissue repair via targeting macrophage polarization, June 29, 2018, Guangdong Pharmaceutical University, Guangzhou, China. 2018.

Rong J., Targeting macrophages as a new anti-obesity mechanism, The 1st Annual meeting for Hong Kong Association of Herbal Medicines, 2018.05.19, Hong Kong, China.. 2018.

Rong J. and Lao L., Unexpected antidepressant and analgesic activities of Chinese medicine puerarin and its molecular targets, 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). 2017.

Wang L.Z., Feng L., Li R.T., Yang S.X., He Y.Q., Wang Q.A., Zhang Q., Zhang Z.T., Rong J., Zhou L.G., Qing J.C., Jia A.C., Gao K., Gao J.M., Huang J. and Zhang W.H., Associate Editor, 副主编, In: Gao Jingmin, Phytochemistry. 植物化学, Science Press, 2017, III: 355.

Wang X., Wang G.C., Rong J., Wang S., Ng T.B., Zhang Y., Lee C.K.F., Zheng L., Wong H.K. and Sze C.W.S., Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome, Frontiers in Pharmacology. 2018, 9.

Wei J., CHENG Y., Guo W.H., Wang D.C., Zhang Q., Li D., Rong J. and Gao J.M., Molecular Diversity and Potential Anti-neuroinflammatory Activities of Cyathane Diterpenoids from the Basidiomycete Cyathus africanus, Scientific Reports. 2017, 7.

Zhao J., Rong J. and Lao L., Unexpected Antidepressant and Analgesic Activities of Chinese Medicine Puerarin and its Molecular Targets, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Zhao J., Lao L. and Rong J., Unexpected antidepressant and analgesic activities of Chinese medicine puerarin and its molecular targets, The 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), August 18 - 20, 2017, Guangzhou, China. 2017.

Researcher : SUN Y

List of Research Outputs

SUN Y. and Chen J., The theory development of traditional Chinese medicine constitution: a review, Journal of Traditional Chinese Medical Sciences. 2018, 5: 16-28.

Researcher : Shen J

Project Title:	Biochemical Society Meeting 679 University of Essex UK - Stress, Signalling and Control Reactive Oxygen Species Mediate Intracellular Cholesterol Accumulation via Modulating Caveolin-1 Pathway in Chinese Hamster Ovary Cells
Investigator(s):	Shen J
Department:	Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	07/2003

Project Title:	Elucidating peroxynitrite as a cellular signaling molecule for regulating neurogenesis under hypoxic and ischemic conditions
Investigator(s):	Shen J, Yang D, Chen X
Department:	School of Chinese Medicine
Source(s) of Funding:	National Natural Science Foundation of China (NSFC) - General Program
Start Date:	01/2013

Project Title:	Elucidating effects of APPL2 on regulating proliferation and cell fate decision of neural stem/progenitor cells through activating Notch signaling pathway
Investigator(s):	Shen J, So KF, Chung SK
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2014
Completion Date:	01/2018

Project Title:	Exploring Caveolin-1 as a Novel Molecular Target for Hampering T lymphocytes Infiltration through Blood Brain Barrier and Attenuating Disease Progress in Experimental Autoimmune Encephalomyelitis
Investigator(s):	Shen J, Chan GCF, Wu W
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	10/2014
Completion Date:	10/2017

Project Title:	Exploring HMGB1 signaling as molecular target in peroxynitrite-mediated blood brain barrier disruption and hemorrhage transformation in ischemia-reperfused brain with delayed thrombolytic therapy
Investigator(s):	Shen J, Yang D, Chung SK
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	10/2015

Project Title:	Elucidating Impacts of Reactive Nitrogen Species-mediated Excessive Mitophagy on Cerebral Ischemic-Reperfusion Injury and Exploring the Neuroprotective Mechanisms of Naringin for Inhibition of Excessive Mitophagy
Investigator(s):	Shen J, Chen X
Department:	School of Chinese Medicine
Source(s) of Funding:	National Natural Science Foundation of China (NSFC) - General Program
Start Date:	01/2016

Project Title:	Exploring Effects of Glycyrrhizin, an Active Compound from Glycyrrhizae Radix, on Attenuating Delayed Tissue-plasminogen Activator (t-PA) Treatment-induced Hemorrhagic Transformation in Ischemic Stroke
Investigator(s):	Shen J, Chen X, Fung ML, Chen H
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	05/2016

Project Title:	Evaluating the neuroprotective effect and safety of An-Gong-Niu-Huang Wan and its ingredients in ischemic stroke
Investigator(s):	Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Matching Grant for Joint Research
Start Date:	06/2016

Project Title:	Exploring Molecular Targets for Drug Discovery to Preventing Hyperglycemia-mediated Hemorrhagic transformation in Ischemic Stroke: Sodium Danshensu (SDSS) as an Example
Investigator(s):	Shen J, Siu DCW, Chung SK
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	09/2017

List of Research Outputs

Cai C., Wu Q., Luo Y., Ma H., Shen J., Zhang Y., Yang L., Chen Y. and Wen Z., In silico prediction of ROCK II inhibitors by different classification approaches. , Molecular Diversity. Aug 7, 2017, DOI: 10.1007/s11030-017-9772-5.. 2017.

Chan L.K., Ganotice F.J.A., Wong F.K.Y., Lau W.C.S., Bridges S.M., Chan C.H.Y., Chan N.K., Chan W.L.P., Chen H., Chen J.Y., Chu K.P.J., Ho C.C., Ho J.M.C., Lam T.P., Lam S.F., Li Q., Shen J., Tanner J.A., Tso W.Y.W., Wong A.K.C., Wong G.T.C., Wong J.Y.H., Wong N.S., Worsley A.J., Yu L.K. and Yum T.P., Implementation of an interprofessional team-based learning program involving seven undergraduate health and social care programs from two universities, and students’ evaluation of their readiness for interprofessional learning, BMC Medical Education. 2017, 17.

Chen H. and Shen J., 13th International Symposium on Healthy Aging, Young Investigator Award (Poster Category) Supported by Sun Chieh Yeh Heart Foundation, Research Center of Heart, Brain, Hormone & Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2018.

Chen H., GUAN B., Chen X., Chen X., Li C., Qiu J., Yang D., Liu K., Qi S. and Shen J., Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway, Translational Stroke Research. Springer US, 2017.

Chen H., GUAN B. and Shen J., Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO-MMP9 pathway, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 第十屆龐鼎元國際中醫藥研討會, 2017, 102.

Chen H. and Shen J., Glycyrrhizin Attenuated Hemorrhagic Transformation and Improved Neurological Outcomes in Ischemic Stroke with Delayed t-PA Treatment, Possibly through Inhibiting the Interaction of Peroxynitrite and HMGB1 Signaling Pathways, 13th International Symposium on Healthy Aging. 2018.

Chen H. and Shen J., One-compound-multi-target: combination of natural compound with delayed tissue plasminogen activator for ischemic stroke treatment, 一个单体多个靶点：天然化合物与组织纤维蛋白溶酶原激活剂（t-PA）联用应用于急性脑卒中的展望, 中藥實驗藥理分會第十三次學術會議, 2017, 148.

Chen H. and Shen J., Peroxynitrite is an important target mediating hemorrhagic transformation induced by delayed tissue plasminogen activator (t-PA) treatment in ischemic stroke: potential application of natural compound baicalin , 中藥實驗藥理分會第十三次會議, 2017, 147.

Chen H. and Shen J., Poster Presentation Award, 中华中医药学会中药实验药理分会, 2017.

Chen H., Chen X., LI W. and Shen J., Targeting RNS/caveolin-1/MMP signaling cascades to protect against cerebral ischemia-reperfusion injuries: potential application for drug discovery, Acta Pharmacologica Sinica. 2018.

Chen X., Zhou B., Yan T., Wu H., Feng J., Chen H., GAO C., Peng T., Yang D. and Shen J., Peroxynitrite enhances self-renewal, proliferation and neuronal differentiation of neural stem/progenitor cells through activating HIF-1α and Wnt/β-catenin signaling pathway, Free Radical Biology and Medicine. 2018, 117: 158-167.

Deng R., Zhou B., Guan B., Chan G.C.F. and Shen J., Marine algae extract attenuated osteoporosis in OVX mice, enhanced osteogenesis on human mesenchymal stem cells and promoted OPG expression, In: Vincenzo Fogliano, Journal of Functional Foods. ELSEVIER, 2017, 40: 229-237.

Gao C., Du Q., LI W., Deng R., Wang Q., Xu A. and Shen J., Baicalin Modulates APPL2/Glucocorticoid Receptor Signaling Cascade, Promotes Neurogenesis, and Attenuates Emotional and Olfactory Dysfunctions in Chronic Corticosterone-Induced Depression, Molecular Neurobiology. 2018.

PENG F., Tang H., Liu P., Shen J., Guan X., Xie X., Gao J., Jia L., Chen J. and Peng C., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis., Scientific Reports . 2017, 7(1):9022.

Shen J., Development of Innovative Learning Methods for Inter-professional Team-Based Learning Programme Involving Undergraduate Students in Western Medicine and Chinese Medicine Curriculum., Promoting Excellence in Education and Research, International Academy of Educational Services Conference. July 27-July 31, 2017. London, England. 2017.

Shen J., GUAN B., ZHAO L., DU Q. and Chen H., Network pharmacology study for traditional Chinese Medicine formula: treatment of ischemic stroke and osteoporosis with Kidney and Qi tonifying and blood-activating formula, 补肾益气活血方对脑卒中和骨质疏松症异病同治的药效观察及共同信号通路的网络药理学探索, 中医方证代谢组学研究进展(2017年卷), 2017.

Shen J., Neural Stem Cells and its Application for Brain Repair: Opportunity for Drug Dsicovery from Traditional CHinese Medicine, Sino-American Technology & Engineering Conference, National Council Chinese Institute of Engineers/USA, Jinan, Shangdong, China, May 13, 20, 2018 . 2018.

Shen J., Chen H. and FENG J., Peroxynitrite could be a critical therapeutic target for preventing hemorrhagic transformation and poor outcome in ischemia-reperfused rat brains with delayed thrombolysis, 7th Global Experts Meeting on NEUROPHARMACOLOGY. 2017, 3: 66.

Shen J., TCM Pathogenesis, Traditional Chinese Medicine. People's Health Publishing Inc., 2017, Chapter 4.

Shen J., Target Neural Stem Cells: Challenge and Opportunity of Traditional Chinese medicine, 神經幹細胞靶向腦修復策略及其在中醫藥的應用, In: Holistic Integrative Pharmacology: 2018 Harbin Summit of Chinmedomics and Drug Metabolism, June 22-24, 2018, 2018.

Tang H., PENG F., Huang X., Xie X., Chen B., Shen J., GAO F., YOU J. and Chen J., Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-β-catenin signaling in breast cancer., Curr Cancer Drug Targets. . 2017, 2017.

Researcher : Sze CW

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS, Zhang Y, Tong Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Support Programme (Tier 2)
Start Date:	12/2009

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	02/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	02/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	07/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	09/2010

Project Title:	The mechanism of Chinese Yam protein (DOI) in modulating NF-κB expression and down-stream inflammation and oxidative stress responses in ovarian aging
Investigator(s):	Sze CWS, Lee CKF, Lao L, Zhang Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	04/2016
Completion Date:	09/2017

Project Title:	Study of target-based Chinese herbal medicine in suppression of aberrant cryptic foci: implication of colon cancer prevention
Investigator(s):	Sze CWS, Lao L, Zhang Y, Xu K
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	08/2017

Project Title:	Research and Development of the Chinese Medicine Formula ZB and Its Bioactive Compounds as Adjuvant Therapy for Colon Cancer and for Alleviation of Chemotherapy-Induced Osteoporosis using Network and Systems Pharmacological Approaches
Investigator(s):	Sze CWS, Lao L, Zhang Y, Leung GPH, Lam JKW
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Support Programme (Tier 3)
Start Date:	10/2017

List of Research Outputs

Researcher : Sze CWS

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS, Zhang Y, Tong Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Support Programme (Tier 2)
Start Date:	12/2009

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	02/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	02/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	07/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	09/2010

Project Title:	The mechanism of Chinese Yam protein (DOI) in modulating NF-κB expression and down-stream inflammation and oxidative stress responses in ovarian aging
Investigator(s):	Sze CWS, Lee CKF, Lao L, Zhang Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	04/2016
Completion Date:	09/2017

Project Title:	Study of target-based Chinese herbal medicine in suppression of aberrant cryptic foci: implication of colon cancer prevention
Investigator(s):	Sze CWS, Lao L, Zhang Y, Xu K
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	08/2017

Project Title:	Research and Development of the Chinese Medicine Formula ZB and Its Bioactive Compounds as Adjuvant Therapy for Colon Cancer and for Alleviation of Chemotherapy-Induced Osteoporosis using Network and Systems Pharmacological Approaches
Investigator(s):	Sze CWS, Lao L, Zhang Y, Leung GPH, Lam JKW
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Support Programme (Tier 3)
Start Date:	10/2017

List of Research Outputs

CHEN X., LAM K.H., CHEN Q., Leung G.P.H., Tang S.C.W., Sze C.W.S., Xiao J., Feng F., Wang Y., Zhang Y. and Zhang Z., Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats, Food and Chemical Toxicology. 2017, 110: 49-61.

CHEN X., Leung G.P.H., Zhang Z., Xiao J.B., Lao L., Feng F., Mak J.C.W., Wang Y., Sze C.W.S. and Zhang Y., Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil, Food and Chemical Toxicology. 2017, 107: 248-260.

WANG X., WANG S., WANG G.C., NG T.B., Zhang Y. and Sze C.W.S., Identification of the target-based Chinese medicine steroidogenic components derived from Gardenia jasminoides Ellis potentially for menopause syndrome based on network and systemic pharmacological studies. , 16th Meeting of the Consortium for Globalization of Chinese medicine. China . Guangdong Provincial Hospital of Chinese, 2017.

Wang X., Wang G.C., Rong J., Wang S., Ng T.B., Zhang Y., Lee C.K.F., Zheng L., Wong H.K. and Sze C.W.S., Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome, Frontiers in Pharmacology. 2018, 9.

Researcher : Tan HY

List of Research Outputs

Researcher : Tan HYH

List of Research Outputs

Cheng C., Chen J., Tan H.Y.H., Wang N., Chen Z. and Feng Y., Scutellaria baicalensis and Cancer Treatment: Recent Progress and Perspectives in Biomedical and Clinical Studies , The American Journal of Chinese Medicine. 2018, 1-30.

GUO W., Tan H.Y.H., Wang N., Wang X. and Feng Y., Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation, Cancer management and research. 2018, 10: 715-734.

HONG M., Zhang Y., LI S., Tan H.Y.H., Wang N., Mu S., Hao X. and Feng Y., A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae, Molecules. 2017, 22: 1617.

Huang J., Cheung F., Tan H.Y.H., HONG M., Wang N., Yang J., Feng Y. and Zheng Q., Identification of the active compounds and significant pathways of yinchenhao decoction based on network pharmacology, Molecular Medicine Reports. 2017.

LI S., Wang N., HONG M., Tan H.Y.H., Pan G. and Feng Y., Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components, Molecules. 2018, 23: 352.

LI S., Tan H.Y.H., Wang N., Cheung F., HONG M. and Feng Y., The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases., Oxidative medicine and cellular longivety. 2018, 4.

Tan H.Y.H., Wang N., Takahashi M. and Feng Y., NYG, A Novel Pigmented Fraction of Saw Palmetto, Suppresses Tumour Angiogenesis and Progression of Human Hepatocellular Carinoma, 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Tan H.Y.H., Wang N., LI S., HONG M., GUO W., Man K., Cheng C., Chen Z. and Feng Y., Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs β-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma., Cellular Physiology and Biochemistry. 2018, 47: 1819-1834.

Tan H.Y.H., Wang N. and Feng Y., Targeting tumour associated macrophages by traditional Chinese medicines , The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Wang N., Tan H.Y.H., LI S. and Feng Y., Atg9b Deficiency Suppresses Autophagy and Potentiates Endoplasmic Reticulum Stress-Associated Hepatocyte Apoptosis in Hepatocarcinogenesis, Theranostics. 2017, 7: 2325-2338.

Wang N., Tan H.Y.H., Chan Y.T., GUO W., LI S. and Feng Y., Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde, Oncotarget. 2017, 8.

Wang N., Tan H.Y.H., LI S., XU Y., GUO W. and Feng Y., Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant, Oxidative Medicine and Cellular Longevity. 2017, 2017: 1-13.

ZHANG C., Wang N., Tan H.Y.H., GUO W., LI S. and Feng Y., Targeting VEGF/VEGFRs Pathway in the Antiangiogenic Treatment of Human Cancers by Traditional Chinese Medicine, Integrative Cancer Therapies. 2018, 17: 582-601.

Zhang C., XU Y., Tan H.Y.H., LI S., Wang N., Zhang Y. and Feng Y., Neuroprotective effect of He-Ying-Qing-Re formula on retinal ganglion cell in diabetic retinopathy, Journal of Ethnopharmacology. 2018, 214: 179-189.

Researcher : Tang H

List of Research Outputs

PENG F., Tang H., Liu P., Shen J., Guan X., Xie X., Gao J., Jia L., Chen J. and Peng C., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis., Scientific Reports . 2017, 7(1):9022.

PENG F., Tang H., Peng C. and Chen K., Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis, explore . 2017.

Tang H., PENG F., Huang X., Xie X., Chen B., Shen J., GAO F., YOU J. and Chen J., Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-β-catenin signaling in breast cancer., Curr Cancer Drug Targets. . 2017, 2017.

Researcher : Tong Y

Project Title:	A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials
Investigator(s):	Tong Y, Shen J, Zhong L, Diu CK
Department:	School of Chinese Medicine
Source(s) of Funding:	Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:	09/2009

Researcher : WANG S

List of Research Outputs

WANG X., WANG S., WANG G.C., NG T.B., Zhang Y. and Sze C.W.S., Identification of the target-based Chinese medicine steroidogenic components derived from Gardenia jasminoides Ellis potentially for menopause syndrome based on network and systemic pharmacological studies. , 16th Meeting of the Consortium for Globalization of Chinese medicine. China . Guangdong Provincial Hospital of Chinese, 2017.

Wang X., Wang G.C., Rong J., Wang S., Ng T.B., Zhang Y., Lee C.K.F., Zheng L., Wong H.K. and Sze C.W.S., Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome, Frontiers in Pharmacology. 2018, 9.

Researcher : WANG X

List of Research Outputs

WANG X., WANG S., WANG G.C., NG T.B., Zhang Y. and Sze C.W.S., Identification of the target-based Chinese medicine steroidogenic components derived from Gardenia jasminoides Ellis potentially for menopause syndrome based on network and systemic pharmacological studies. , 16th Meeting of the Consortium for Globalization of Chinese medicine. China . Guangdong Provincial Hospital of Chinese, 2017.

Wang X., Wang G.C., Rong J., Wang S., Ng T.B., Zhang Y., Lee C.K.F., Zheng L., Wong H.K. and Sze C.W.S., Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome, Frontiers in Pharmacology. 2018, 9.

Researcher : WU W

List of Research Outputs

You Y., WU W., Lan H., Cheng Y. and Chen H., A novel small molecule from Ganoderma Lucidum attenuates renal fibrosis in mouse UUO model, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Researcher : Wang MN

Project Title:	The role of myeloid-derived suppressor cells in acute alcoholic liver disease
Investigator(s):	Wang N, Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for New Staff
Start Date:	06/2016
Completion Date:	12/2017

Project Title:	Hepatic SBP2 expression alleviates acute and chronic liver injury caused by alcohol beverage via suppressing inflammasome activation in hepatocytes
Investigator(s):	Wang N, Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	06/2017

Project Title:	The suppressive effect of carnosic acid on human hepatocellular carcinoma: Involvement of Fli1
Investigator(s):	Wang N, Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:	07/2017
Completion Date:	11/2017

Project Title:	Investigation on the effect of berberine on improvement of diabetic retinopathy in insulin-treated diabetic mellitus
Investigator(s):	Wang N, Feng Y, Chen H
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	04/2018

Project Title:	25th Biennial Congress of the European Association for Cancer Research; The role of autophagy-related protein 9B in liver carcinogenesis
Investigator(s):	Wang N
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	06/2018
Completion Date:	07/2018

List of Research Outputs

Researcher : Wang N

Project Title:	The role of myeloid-derived suppressor cells in acute alcoholic liver disease
Investigator(s):	Wang N, Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for New Staff
Start Date:	06/2016
Completion Date:	12/2017

Project Title:	Hepatic SBP2 expression alleviates acute and chronic liver injury caused by alcohol beverage via suppressing inflammasome activation in hepatocytes
Investigator(s):	Wang N, Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	06/2017

Project Title:	The suppressive effect of carnosic acid on human hepatocellular carcinoma: Involvement of Fli1
Investigator(s):	Wang N, Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:	07/2017
Completion Date:	11/2017

Project Title:	Investigation on the effect of berberine on improvement of diabetic retinopathy in insulin-treated diabetic mellitus
Investigator(s):	Wang N, Feng Y, Chen H
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	04/2018

Project Title:	25th Biennial Congress of the European Association for Cancer Research; The role of autophagy-related protein 9B in liver carcinogenesis
Investigator(s):	Wang N
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	06/2018
Completion Date:	07/2018

List of Research Outputs

Cheng C., Chen J., Tan H.Y.H., Wang N., Chen Z. and Feng Y., Scutellaria baicalensis and Cancer Treatment: Recent Progress and Perspectives in Biomedical and Clinical Studies , The American Journal of Chinese Medicine. 2018, 1-30.

GUO W., Tan H.Y.H., Wang N., Wang X. and Feng Y., Deciphering hepatocellular carcinoma through metabolomics: from biomarker discovery to therapy evaluation, Cancer management and research. 2018, 10: 715-734.

HONG M., Zhang Y., LI S., Tan H.Y.H., Wang N., Mu S., Hao X. and Feng Y., A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae, Molecules. 2017, 22: 1617.

Huang J., Cheung F., Tan H.Y.H., HONG M., Wang N., Yang J., Feng Y. and Zheng Q., Identification of the active compounds and significant pathways of yinchenhao decoction based on network pharmacology, Molecular Medicine Reports. 2017.

Huang J., LI L., Cheung F., Wang N., Li Y., Fan Z., Yin F., Yang J., Gao R., He Y. and Feng Y., Network Pharmacology-Based Approach to Investigate the Analgesic Efficacy and Molecular Targets of Xuangui Dropping Pill for Treating Primary Dysmenorrhea, Evidence-Based Complementary and Alternative Medicine. 2017, 2017: 1-12.

LI S., Wang N., HONG M., Tan H.Y.H., Pan G. and Feng Y., Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components, Molecules. 2018, 23: 352.

LI S., Tan H.Y.H., Wang N., Cheung F., HONG M. and Feng Y., The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases., Oxidative medicine and cellular longivety. 2018, 4.

Tan H.Y.H., Wang N., Takahashi M. and Feng Y., NYG, A Novel Pigmented Fraction of Saw Palmetto, Suppresses Tumour Angiogenesis and Progression of Human Hepatocellular Carinoma, 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Tan H.Y.H., Wang N., LI S., HONG M., GUO W., Man K., Cheng C., Chen Z. and Feng Y., Repression of WT1-Mediated LEF1 Transcription by Mangiferin Governs β-Catenin-Independent Wnt Signalling Inactivation in Hepatocellular Carcinoma., Cellular Physiology and Biochemistry. 2018, 47: 1819-1834.

Tan H.Y.H., Wang N. and Feng Y., Targeting tumour associated macrophages by traditional Chinese medicines , The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Wang N., Tan H.Y.H., LI S. and Feng Y., Atg9b Deficiency Suppresses Autophagy and Potentiates Endoplasmic Reticulum Stress-Associated Hepatocyte Apoptosis in Hepatocarcinogenesis, Theranostics. 2017, 7: 2325-2338.

Wang N., Tan H.Y.H., Chan Y.T., GUO W., LI S. and Feng Y., Identification of WT1 as determinant of heptatocellular carcinoma and its inhibition by Chinese herbal medicine Salvia chinensis Benth and its active ingredient protocatechualdehyde, Oncotarget. 2017, 8.

Wang N., Tan H.Y.H., LI S., XU Y., GUO W. and Feng Y., Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant, Oxidative Medicine and Cellular Longevity. 2017, 2017: 1-13.

ZHANG C., Wang N., Tan H.Y.H., GUO W., LI S. and Feng Y., Targeting VEGF/VEGFRs Pathway in the Antiangiogenic Treatment of Human Cancers by Traditional Chinese Medicine, Integrative Cancer Therapies. 2018, 17: 582-601.

Zhang C., XU Y., Tan H.Y.H., LI S., Wang N., Zhang Y. and Feng Y., Neuroprotective effect of He-Ying-Qing-Re formula on retinal ganglion cell in diabetic retinopathy, Journal of Ethnopharmacology. 2018, 214: 179-189.

Researcher : Wang S

List of Research Outputs

Researcher : Wong HK

List of Research Outputs

Wang X., Wang G.C., Rong J., Wang S., Ng T.B., Zhang Y., Lee C.K.F., Zheng L., Wong H.K. and Sze C.W.S., Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome, Frontiers in Pharmacology. 2018, 9.

Researcher : Wong MK

List of Research Outputs

Lam W.L., Yeung W.F., Wong M.K., Cheung C.W., Chan K.K.L., Ngan H.Y.S., Wong C.K.H., Chen H. and Lao L., Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial, Trials. 2018, 19: 8.

Researcher : Wu H

List of Research Outputs

Chen X., Zhou B., Yan T., Wu H., Feng J., Chen H., GAO C., Peng T., Yang D. and Shen J., Peroxynitrite enhances self-renewal, proliferation and neuronal differentiation of neural stem/progenitor cells through activating HIF-1α and Wnt/β-catenin signaling pathway, Free Radical Biology and Medicine. 2018, 117: 158-167.

Researcher : Wu J

Project Title:	Anti-cystic hyperplasia of breast herbal medicine research
Investigator(s):	Wu J, Chow LWC
Department:	School of Chinese Medicine
Source(s) of Funding:	Other Funding Scheme
Start Date:	05/2001

Project Title:	Anti-prostatomegaly herbal medicine research
Investigator(s):	Wu J, Leung SYL
Department:	School of Chinese Medicine
Source(s) of Funding:	Other Funding Scheme
Start Date:	06/2001

Researcher : Wu J

Project Title:	Activation on Left Dorsolateral Prefrontal Cortex（LDPC）with Different Acupoint-Combinations for Depression：An fNIRS Study
Investigator(s):	Wu J, Lao L, Chan WC, Zhu FF, Zhang Z, Yeung WF, Chen H
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research for New Staff
Start Date:	06/2015

List of Research Outputs

CUI B., YANG J. and Wu J., Effect of acupuncture combined nerve block on patients undergoing surgery: a meta-analysis, 針刺聯合頸部阻滯對麻醉效果影響的Meta分析, Journal of Clinical Anesthesiology. 臨床麻醉學雜志, 2018, 34: 159-162.

Wu J., A synergistic Effects Study on Stimulation at Channel-cutaneous Region of Hand and Foot for Patients with Hypertension in Grade Ⅱ and Ⅲ, 16th Consortium for Globalization of Chinese Medicine (CGCM). 2017.

Wu J., Acupuncture Effecting on the Emotional Processing Function in the Cerebral Area of the Depressive Patients: A pilot Study with fNIRS., International Scientific Acupuncture and Meridian Symposium. 2017.

Wu J., Systematic Review on Effectiveness of Acupuncture for Anxiety Disorder, International Scientific Acupuncture and Meridian Symposium. 2017.

Wu J., The effect of antihypertension of stimulating on channel-skin regions of hands and feet for Hypertension, 16th Consortium for Globalization of Chinese Medicine (CGCM). 2017.

Researcher : XU Y

List of Research Outputs

Wang N., Tan H.Y.H., LI S., XU Y., GUO W. and Feng Y., Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant, Oxidative Medicine and Cellular Longevity. 2017, 2017: 1-13.

Zhang C., XU Y., Tan H.Y.H., LI S., Wang N., Zhang Y. and Feng Y., Neuroprotective effect of He-Ying-Qing-Re formula on retinal ganglion cell in diabetic retinopathy, Journal of Ethnopharmacology. 2018, 214: 179-189.

Researcher : YOU J

List of Research Outputs

Tang H., PENG F., Huang X., Xie X., Chen B., Shen J., GAO F., YOU J. and Chen J., Neoisoliquiritigenin inhibits tumor progression by targeting GRP78-β-catenin signaling in breast cancer., Curr Cancer Drug Targets. . 2017, 2017.

Researcher : Yang C

List of Research Outputs

Du .., Ren .., Ge .., Yang C. and Liang .., Literature-based Study on Association Between Physical Characteristics of Luo-Connecting Acupoint and Its Diagnostic Use, 基于文献回顾探讨络穴物理特性与诊断的关联作用, Liaoning Journal of Traditional Chinese Medicine. 辽宁中医杂志, 2018, 45: 473-478.

Luo .., Zhou .., Yang C., Zheng .. and Liang .., Confounding factors in research for characteristics of acupoint electrical impedance, 经穴电阻抗特性研究中相关干扰因素分析探讨, Zhongguo zhen jiu = Chinese acupuncture & moxibustion. 中国针灸, Beijing, 2018, 38: 83-6.

Sun .., Zhang .., Wang .., Yang C., Chang .., Geng .., Yang .., Zhuang .., Wang .., Xie .., Huang .., Zhao .., Zhou .., Cheng .., Cai .., Wu .. and Yu .., Regulating the Balance of Th17/Treg via Electroacupuncture and Moxibustion: An Ulcerative Colitis Mice Model Based Study, In: Ciara Hughes, Evidence-Based Complementary and Alternative Medicine. Hindawi, 2017, 2017: 1-13.

Yang C., Du .., Sun .., Long .., Li .., Shen .., Wu .., Lao L. and Liang .., Acupuncture for stable angina pectoris: a systematic review protocol, BMJ Open. the BMJ Publishing Group Ltd., 2018, 8: e019798.

Researcher : Yeung WF

Project Title:	A Systemic Review on the Effectiveness of Chinese Herbal Medicine for Depression
Investigator(s):	Yeung WF, Chung KF
Department:	Psychiatry
Source(s) of Funding:	Hospital Authority - General Award
Start Date:	02/2013

List of Research Outputs

Lam W.L., Yeung W.F., Wong M.K., Cheung C.W., Chan K.K.L., Ngan H.Y.S., Wong C.K.H., Chen H. and Lao L., Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial, Trials. 2018, 19: 8.

Researcher : Yiu YM

List of Research Outputs

Yiu Y.M., Research on the Prevention and Treatment of Sub-health by Acupuncture and Moxibustion, Chinese Medicine 2018.

Researcher : You Y

List of Research Outputs

You Y., Lan H., Cheng Y. and Chen H., A Novel Small Molecule from Ganoderma lucidum Attenuates Renal Fibrosis in Obstructive Nephropathy, The 2nd Annual Conference of the Special Committee of Research on Safety of Clinical Usage of Drugs WFCMS (World Federation of Chinese Medicine Societies). 2017.

You Y., WU W., Lan H., Cheng Y. and Chen H., A novel small molecule from Ganoderma Lucidum attenuates renal fibrosis in mouse UUO model, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Researcher : Yum TP

List of Research Outputs

Chan L.K., Ganotice F.J.A., Wong F.K.Y., Lau W.C.S., Bridges S.M., Chan C.H.Y., Chan N.K., Chan W.L.P., Chen H., Chen J.Y., Chu K.P.J., Ho C.C., Ho J.M.C., Lam T.P., Lam S.F., Li Q., Shen J., Tanner J.A., Tso W.Y.W., Wong A.K.C., Wong G.T.C., Wong J.Y.H., Wong N.S., Worsley A.J., Yu L.K. and Yum T.P., Implementation of an interprofessional team-based learning program involving seven undergraduate health and social care programs from two universities, and students’ evaluation of their readiness for interprofessional learning, BMC Medical Education. 2017, 17.

Researcher : ZHANG C

List of Research Outputs

ZHANG C., Wang N., Tan H.Y.H., GUO W., LI S. and Feng Y., Targeting VEGF/VEGFRs Pathway in the Antiangiogenic Treatment of Human Cancers by Traditional Chinese Medicine, Integrative Cancer Therapies. 2018, 17: 582-601.

Zhang C., XU Y., Tan H.Y.H., LI S., Wang N., Zhang Y. and Feng Y., Neuroprotective effect of He-Ying-Qing-Re formula on retinal ganglion cell in diabetic retinopathy, Journal of Ethnopharmacology. 2018, 214: 179-189.

Researcher : ZHAO L

List of Research Outputs

Shen J., GUAN B., ZHAO L., DU Q. and Chen H., Network pharmacology study for traditional Chinese Medicine formula: treatment of ischemic stroke and osteoporosis with Kidney and Qi tonifying and blood-activating formula, 补肾益气活血方对脑卒中和骨质疏松症异病同治的药效观察及共同信号通路的网络药理学探索, 中医方证代谢组学研究进展(2017年卷), 2017.

Researcher : ZHAO Y

List of Research Outputs

Chen H., NING Z., LAM W.L., ZHAO Y., Lun W.M., Ng B.F.L., Ziea E.T.C. and Lao L., How to design a control in acupuncture randomized controlled trials, The 16th Meeting of Consortium for Globalization of Chinese Medicine 2017.

Researcher : Zhang C

List of Research Outputs

Researcher : Zhang Y

Project Title:	Development of a nanoparticle based diagnostic platform for screening active ingredients from Traditional Chinese Medicine extracts
Investigator(s):	Zhang Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	06/2015
Completion Date:	06/2018

Project Title:	Discovery of characteristic chemical markers rapidly to detect sulfur-fumigated herbs
Investigator(s):	Zhang Y, Sze CWS, Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Translational and Applied Research
Start Date:	04/2016

Project Title:	Mechanistic study on the role of Dendrobium officinale polysaccharides on modulating aquaporin 5 and mucin5AC expressions in ameliorating chronic obstructive pulmonary disease
Investigator(s):	Zhang Y, Sze CWS, Lao L, Lee CKF
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	06/2016
Completion Date:	06/2018

Project Title:	BIT’s 5th Annual World Congress of Food and Nutrition-2016; Polysaccharides of Dendrobium officinale Induce Aquaporin 5 Translocation by Activating M3 Muscarinic Receptors
Investigator(s):	Zhang Y
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	11/2016

Project Title:	The pharmacology mechanisms and safety study on the dendrobine granula jointed cisplatin to enhance the non-small cell lung cancer therapeutic efficacy
Investigator(s):	Zhang Y, Lao L, Sze CWS
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	04/2017

Project Title:	The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):	Zhang Y, Tang SCW, Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	Matching Grant for Joint Research
Start Date:	03/2018

Project Title:	The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):	Zhang Y, Tang SCW, Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	04/2018

Project Title:	The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):	Zhang Y, Tang SCW, Lao L
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	06/2018

List of Research Outputs

CHEN X., LAM K.H., CHEN Q., Leung G.P.H., Tang S.C.W., Sze C.W.S., Xiao J., Feng F., Wang Y., Zhang Y. and Zhang Z., Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats, Food and Chemical Toxicology. 2017, 110: 49-61.

CHEN X., Leung G.P.H., Zhang Z., Xiao J.B., Lao L., Feng F., Mak J.C.W., Wang Y., Sze C.W.S. and Zhang Y., Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil, Food and Chemical Toxicology. 2017, 107: 248-260.

HONG M., Zhang Y., LI S., Tan H.Y.H., Wang N., Mu S., Hao X. and Feng Y., A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae, Molecules. 2017, 22: 1617.

WANG X., WANG S., WANG G.C., NG T.B., Zhang Y. and Sze C.W.S., Identification of the target-based Chinese medicine steroidogenic components derived from Gardenia jasminoides Ellis potentially for menopause syndrome based on network and systemic pharmacological studies. , 16th Meeting of the Consortium for Globalization of Chinese medicine. China . Guangdong Provincial Hospital of Chinese, 2017.

Wang X., Wang G.C., Rong J., Wang S., Ng T.B., Zhang Y., Lee C.K.F., Zheng L., Wong H.K. and Sze C.W.S., Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome, Frontiers in Pharmacology. 2018, 9.

Researcher : Zhang Y

List of Research Outputs

HONG M., Zhang Y., LI S., Tan H.Y.H., Wang N., Mu S., Hao X. and Feng Y., A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae, Molecules. 2017, 22: 1617.

Researcher : Zhang Z

Project Title:	The Establishment of Neurobehavioral Experiments into the Acupuncture Course (BCHM3003, 針灸學) of Undergraduate Chinese Medicine Programs
Investigator(s):	Zhang Z, Tong Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:	07/2007

Project Title:	The development of a clinical-case search system to introduce case-study learning mode into Chinese medical curricula
Investigator(s):	Zhang Z, Wong HK
Department:	School of Chinese Medicine
Source(s) of Funding:	Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:	09/2008

Project Title:	The herbal medicine Peony-Glycyrrhiza Decoction (PGD) as an adjunctive therapy to treat antipsychotic-induced hyperprolactinemia in female patients with schizophrenia: a double-blind, randomized, placebo-controlled study
Investigator(s):	Zhang Z, Chen EYH
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Health Services Research Fund - Full Grants
Start Date:	02/2012

Project Title:	An assessor-blinded, randomised controlled trial of acupuncture to prevent chemobrain in breast cancer patients
Investigator(s):	Zhang Z, Kwong A, Chan KW, Ho LM, Lee VHF, Lao L, Yeung WF, Sze CKH
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	08/2015

Project Title:	Herbal compounds protect against antipsychotic-induced weight gain and metabolic syndrome in rats
Investigator(s):	Zhang Z
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	04/2016
Completion Date:	03/2018

Project Title:	Resveratrol and ginsenoside Rg1 combination protects against chemotherapy-induced cognitive impairment: synergistic mechanisms of cytokine-modulating and anti-neurotoxic actions
Investigator(s):	Zhang Z, Lai SWC
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	09/2017

Project Title:	A double-blind, randomised,placebo-controlled trial of berberine as an adjuvant to treat antipsychotic-induced metabolic syndrome in patients with schizophrenia spectrum disorders
Investigator(s):	Zhang Z, Chen EYH, Lee HME, Wong HK
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	10/2017

Project Title:	A novel formula of natural compounds to protect against chemotherapy-induced cognitive impairment: a preclinical evaluation
Investigator(s):	Zhang Z
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Translational and Applied Research
Start Date:	03/2018

Project Title:	Structural brain connectomic and blood and urine metabolomic differentiation of reactive and endogenous subtypes of major depressive disorder
Investigator(s):	Zhang Z
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Fund for Basic Research
Start Date:	05/2018

List of Research Outputs

CHEN X., LAM K.H., CHEN Q., Leung G.P.H., Tang S.C.W., Sze C.W.S., Xiao J., Feng F., Wang Y., Zhang Y. and Zhang Z., Ficus virens proanthocyanidins induced apoptosis in breast cancer cells concomitantly ameliorated 5-fluorouracil induced intestinal mucositis in rats, Food and Chemical Toxicology. 2017, 110: 49-61.

CHEN X., Leung G.P.H., Zhang Z., Xiao J.B., Lao L., Feng F., Mak J.C.W., Wang Y., Sze C.W.S. and Zhang Y., Proanthocyanidins from Uncaria rhynchophylla induced apoptosis in MDA-MB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil, Food and Chemical Toxicology. 2017, 107: 248-260.

Chung K.F., Yeung W.F., Yu B.Y., Leung F.C., Zhang S.P., Zhang Z., Ng R.M. and Yiu G.C., Acupuncture with or without combined auricular acupuncture for insomnia: a randomised, waitlist-controlled trial., Acupunct Med. 2017, 2017 Dec 11. pii: acupmed-2017-011371. doi: 10.1136/acupmed-.

Ng S.M., LENG L., Ho R.T.H., Zhang Z. and WANG Q., A Brief Body-Mind-Spirit Group Therapy for Chinese Medicine Stagnation Syndrome: A Randomized Controlled Trial, Evidence-Based Complementary and Alternative Medicine. Hindawi, 2018, 2018: 1-12.

Wong W., Lam C.L.K., Bian X.Z., Zhang Z., Ng S.T. and Tung S., Morbidity pattern of traditional Chinese medicine primary care in the Hong Kong population, Scientific Reports. 2017, 7: 7513.

Yeung W.F., Ho F.Y., Chung K.F., Zhang Z., Yu B.Y., Suen L.K., Chan L.Y., Chen H.Y., Ho L.M. and Lao L., Self-administered acupressure for insomnia disorder: a pilot randomized controlled trial, Journal of Sleep Research. 2018, 27: 220-231.

Ying J., Zhou M.J., Chen H., Chen L., Zhang L., Ji J., Yu C. and Zhang Z., Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial, Chinese Journal of Integrative Medicine. 2018.

Researcher : Zhao J

Project Title:	Transcriptomic profiling of the gene networks reveals the roles of BDNF and RragA in the anti-depressive and analgesic activities of Chinese medicine Puerarin
Investigator(s):	Zhao J, Rong J, Lao L, Meng W
Department:	School of Chinese Medicine
Source(s) of Funding:	Health and Medical Research Fund - Mini Grant
Start Date:	04/2018

List of Research Outputs

LUO D., Guo Y., CHENG Y., Zhao J., Wang Y. and Rong J., Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways, Aging. 2017.

Zhao J., Rong J. and Lao L., Unexpected Antidepressant and Analgesic Activities of Chinese Medicine Puerarin and its Molecular Targets, The 10th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2017.

Zhao J., Lao L. and Rong J., Unexpected antidepressant and analgesic activities of Chinese medicine puerarin and its molecular targets, The 16th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), August 18 - 20, 2017, Guangzhou, China. 2017.

Researcher : Zhou B

List of Research Outputs

Chen X., Zhou B., Yan T., Wu H., Feng J., Chen H., GAO C., Peng T., Yang D. and Shen J., Peroxynitrite enhances self-renewal, proliferation and neuronal differentiation of neural stem/progenitor cells through activating HIF-1α and Wnt/β-catenin signaling pathway, Free Radical Biology and Medicine. 2018, 117: 158-167.

Deng R., Zhou B., Guan B., Chan G.C.F. and Shen J., Marine algae extract attenuated osteoporosis in OVX mice, enhanced osteogenesis on human mesenchymal stem cells and promoted OPG expression, In: Vincenzo Fogliano, Journal of Functional Foods. ELSEVIER, 2017, 40: 229-237.

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