Research and Scholarship 2005

DEPARTMENT OF ANAESTHESIOLOGY



Researcher : Chan RSN

List of Research Outputs

Lam K.C., Chan R.S.N. and Irwin M.G., Intrathecal morphine for post caesarean section analgesia: a comparison of 3 doses, Asean Journal of Anaesthesiology. Malaysia, 2004, 5: 10-17.
Wong A.Y.C., Chan R.S.N. and Irwin M.G., Anaethetic management of caesarean delivery in a patient with hypoplastic anaemia and severe preeclampsia, Canadian Journal of Anesthesiology. Canada, 2004, 51: 923-927.


Researcher : Chow BFM

List of Research Outputs

Yuen V.M.Y., Chow B.F.M. and Irwin M.G., Severe hypotension and hepatic dysfunction in a patient undergoing scoliosis surgery in the prone position, Anaesthesia Intensive Care. Australia, 2005, 33 (3): 393-399.


Researcher : Greenland KB

List of Research Outputs

Greenland K.B. and Irwin M.G., The Williams Airway Intubator, the Ovassapian Airway and the Berman Airway as upper airway conduits for Fibreoptic bronchoscopy in patients with difficult airways, Current opinion in Anesthesiology. 2004, 17: 505-510.


Researcher : Guo X

List of Research Outputs

Guo X., Irwin M.G., Chan D., Tipoe G.L. and Cheung K.M.C., Differential fuctions of cyclooxygenase 1 and 2 in bone repair, European Cells and Materials. 2005, 10 Suppl. 3: 56.
Guo X. and Cheung K.M.C., The effects of cyclooxygenase - 2 selective non-steroidal anti-inflammatory drugs (NSAIDS) in fracture repair, Best Basic Science Paper Award for Associate Member at the 24th Annual Congress of the Hong Kong Orthopaedic Association, November 13-14, 2004. 2004.
Guo X., Irwin M.G., Cheung K.M.C. and Chan D., The effects of cyclooxygenase -2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair , 9th Rearch Postgraduate Symposium, HKU 4 December 2004 . 2004.
Guo X., Cheung K.M.C., Chan D. and Irwin M.G., The effects of cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair, 24th Annual Congress of the Hong Kong Orthopaedic Association, Hong Kong, November 13-14, 2004.


Researcher : Guo X

List of Research Outputs

Guo X., Irwin M.G., Chan D., Tipoe G.L. and Cheung K.M.C., Differential fuctions of cyclooxygenase 1 and 2 in bone repair, European Cells and Materials. 2005, 10 Suppl. 3: 56.
Guo X. and Cheung K.M.C., The effects of cyclooxygenase - 2 selective non-steroidal anti-inflammatory drugs (NSAIDS) in fracture repair, Best Basic Science Paper Award for Associate Member at the 24th Annual Congress of the Hong Kong Orthopaedic Association, November 13-14, 2004. 2004.
Guo X., Irwin M.G., Cheung K.M.C. and Chan D., The effects of cyclooxygenase -2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair , 9th Rearch Postgraduate Symposium, HKU 4 December 2004 . 2004.
Guo X., Cheung K.M.C., Chan D. and Irwin M.G., The effects of cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair, 24th Annual Congress of the Hong Kong Orthopaedic Association, Hong Kong, November 13-14, 2004.


Researcher : Irwin MG

Project Title:The analgesic efficacy and preemptive action of Parecoxibin gynaecological laparoscopic surgery
Investigator(s):Irwin MG, Li CF, Lee LHY
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:11/2003
Completion Date:10/2004
Abstract:
To evaluate the efficacy of parecoxib in a commonly performed short stay surgical procedure.


Project Title:The role of cyclooxygenase(s) in fracture repair
Investigator(s):Irwin MG
Department:Anaesthesiology
Source(s) of Funding:Incentive Award for RGC CERG Fundable But Not Funded Projects
Start Date:07/2004
Abstract:
Refer to hard copy


List of Research Outputs

Greenland K.B. and Irwin M.G., The Williams Airway Intubator, the Ovassapian Airway and the Berman Airway as upper airway conduits for Fibreoptic bronchoscopy in patients with difficult airways, Current opinion in Anesthesiology. 2004, 17: 505-510.
Guo X., Irwin M.G., Chan D., Tipoe G.L. and Cheung K.M.C., Differential fuctions of cyclooxygenase 1 and 2 in bone repair, European Cells and Materials. 2005, 10 Suppl. 3: 56.
Guo X., Irwin M.G., Cheung K.M.C. and Chan D., The effects of cyclooxygenase -2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair , 9th Rearch Postgraduate Symposium, HKU 4 December 2004 . 2004.
Guo X., Cheung K.M.C., Chan D. and Irwin M.G., The effects of cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in fracture repair, 24th Annual Congress of the Hong Kong Orthopaedic Association, Hong Kong, November 13-14, 2004.
Irwin M.G., Advances in the pharmacological management of acute pain, Korean Society of Anesthesiologists ASM. Korea, 2004.
Irwin M.G., Editorial Board, CPD Anaesthesia (UK). 2005.
Irwin M.G., Editorial Board, Hong Kong Medical Journal. HK, 2005.
Irwin M.G., Invited reviewer, Anaesthesia & Intensive Care. Australia, 2005.
Irwin M.G., Invited reviewer, Anaesthesiology. US, 2005.
Irwin M.G., Invited reviewer, Asean Journal of Anaesthesiology. Malaysia, 2005.
Irwin M.G., Invited reviewer, Asian Journal of Maxillofacial Surgery. 2005.
Irwin M.G., Invited reviewer, British Journal of Anaesthesia. UK, 2005.
Irwin M.G., Invited reviewer, Canadian Journal of Physiology & Pharmacology. Canada, 2005.
Irwin M.G., Invited reviewer, Hong Kong Medical Journal. HK, 2005.
Irwin M.G., Invited reviewer, Journal of Clinical Anaesthesia. 2005.
Irwin M.G., Invited reviewer, Journal of Paediatrics, Obstetrics and Gynaecology. 2005.
Irwin M.G., Invited reviewer, Medical Science Monitor. 2005.
Irwin M.G., Invited reviewer, Surgical Practice. 2005.
Irwin M.G., Ketamine, 1st Peking Union International Conference on Anesthesia & Analgesia. Beijing, China, 2005.
Irwin M.G., Oxygen delivery, The science and practice of perfusion course. Grantham Hospital/HKU. HK, 2004.
Irwin M.G., Perioperative care of paediatric patients in Cambodia, 19th Congress of Asian Association of Paediatric Surgeons. HK, 2004.
Irwin M.G., Preoperative assessment and patient preparation, Annual Scientific Meeting in Anaesthesiology. HK, 2004.
Irwin M.G., Remifentanil, Anhui Medical University Symposium on Anaesthesiology. Hefei, China, 2005.
Irwin M.G., Safe sedation by non-anaesthesiologists, Asia Pacific Dental Congress. KL, Malaysia, 2005.
Irwin M.G., Spine J, Preemptive analgesia. 2005, 5 (2): 229.
Irwin M.G., The role of IT in medical education, Asia Pacific Dental Congress. Malaysia, 2005.
Lam K.C., Chan R.S.N. and Irwin M.G., Intrathecal morphine for post caesarean section analgesia: a comparison of 3 doses, Asean Journal of Anaesthesiology. Malaysia, 2004, 5: 10-17.
Lee L.H.Y., Irwin M.G. and Lui S.K., Intraoperative remifentanil infusion dose not increase postoperative opioid consumption compared with 70% nitrous oxide, Anesthesiology. USA, 2005, 102: 398-402.
Lee L.H.Y., Irwin M.G., Lim J. and Wong C.K., The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section, Anaesthesia. UK, 2004, 59: 876-880.
Sun N.C.H., Wong A.Y.C. and Irwin M.G., A comparison of pain on intravenous injection between two preparations of propofol, Anesthesia and Analgesia. USA, 2005, 101 (3): 675-678.
Wong A.Y.C., Chan R.S.N. and Irwin M.G., Anaethetic management of caesarean delivery in a patient with hypoplastic anaemia and severe preeclampsia, Canadian Journal of Anesthesiology. Canada, 2004, 51: 923-927.
Wong A.Y.C. and Irwin M.G., Large venous air embolism in the sitting position despite monitoring with transoesophageal echocardiography, Anaesthesia. UK, 2005, 60 (8): 811-813.
Yuen T.S.T. and Irwin M.G., The "fifth vital sign", Hong Kong Medical Journal. HK, 2005, 11 (3): 145-146.
Yuen V.M.Y., Chow B.F.M. and Irwin M.G., Severe hypotension and hepatic dysfunction in a patient undergoing scoliosis surgery in the prone position, Anaesthesia Intensive Care. Australia, 2005, 33 (3): 393-399.
Zhang Y., Irwin M.G. and Wong T.M., Remifentanil Preconditioning Protects against Ischemic Injury in the Intact Rat Heart, Anesthesiology. USA, 2004, 101: 918-923.
Zhang Y., Chen Z.W., Irwin M.G. and Wong T.M., Remifentanil mimics cardioprotective effect of ischemic preconditioning via protein kinase C activation in open chest of rats, Acta Pharmacol Sin. 2005, 26(5): 546-50.
Zhang Y., Zhang Y., Irwin M.G. and Wong T.M., Remifentanil mimics the cardioprotective effect of ischemic preconditioning via protein kinase C activation in open chest rats, Acta Pharmacologica Sinica. 2005, 26: 546-550.
Zhang Y., Irwin M.G., Wong T.M., Chen M. and Cao C., Remifentanil preconditioning confers cardioprotection via cardiac kappa- and delta-opioid receptors. Anesthesiology. 2005, 102(2): 371-8.
Zhang Y., Irwin M.G., Wong T.M., Chen M. and Cao C., Remifentanil preconditioning confers cardioprotection via cardiac kappa- and delta-opioid receptors, Anesthesiology. USA, 2005, 102: 371-378.


Researcher : Lee LHY

List of Research Outputs

Lee L.H.Y., Irwin M.G. and Lui S.K., Intraoperative remifentanil infusion dose not increase postoperative opioid consumption compared with 70% nitrous oxide, Anesthesiology. USA, 2005, 102: 398-402.
Lee L.H.Y., Irwin M.G., Lim J. and Wong C.K., The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section, Anaesthesia. UK, 2004, 59: 876-880.


Researcher : Li CF

List of Research Outputs

Tsui S.L., Yong B.H., Ng J.K.F., Yuen T.S.T., Li C.F. and Chui K.Y., Delayed epidural catheter removal: the impact of postoperative coagulopathy, Anesthesia and Intensive Care. Australia, 2004, 32: 630-636.


Researcher : Ng JKF

Project Title:Comparison of the effect on cognitive function of four different regimens in patient-controlled intravenous infusion (PCA) for post operative analgesia in lower abdominal operations
Investigator(s):Ng JKF, Yang JCS
Department:Anaesthesiology
Source(s) of Funding:Low Budget High Impact Programme
Start Date:07/1998
Completion Date:10/2004
Abstract:
To compare the effect on cognitive function of tramadol vs fentanyl, the best 'conventional' opioid so far concerning cognitive impairment. The current study is one of our steps in substantiating further the advantages of tramadol. Our ultimate aim is to do a formal cost-effectiveness analysis of using different opioids which will conclude our search for the 'ideal' analgesic for post-operative PCA.


Project Title:Thrombelastographic profile in elderlies
Investigator(s):Ng JKF
Department:Anaesthesiology
Source(s) of Funding:Other Funding Scheme
Start Date:06/1999
Abstract:
To compare thrombelastrographic profile of healthy elderlies to healthy young adults.


Project Title:Effect of non-steroidal anti-inflammatory agents on platelet function and blood loss in patients undergoing knee replacement surgery
Investigator(s):Ng JKF, Lam CCK, Tang WM
Department:Anaesthesiology
Source(s) of Funding:Low Budget High Impact Programme
Start Date:11/2001
Abstract:
To evaluate a new platelet function analyser (PFA)-100TM) as a preoperative platelet function monitor.


Project Title:A prospective, randomised, double blind, placebo-controlled study on the effects of Ling-Zhi (Ganoderma Lucidum) on platelet and global haemostatic function in healthy volunteers
Investigator(s):Ng JKF, Man RYK, Kwok J.Y.
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:11/2002
Abstract:
To investigate the effect of LZ on global haemostatic and platelet function.


Project Title:The role of pertussis toxin sensitive pathways in EDHF mediated relaxation and milrinone induced vasodilatation in porcine coronary arteries
Investigator(s):Ng JKF, Vanhoutte PMGR, Man RYK
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:11/2004
Abstract:
To evaluate the contribution of the pertussis toxin sensitve G-protein (Gi-protein) signalling pathway in EDHF mediated vascular relaxation; to investigate the contribution of EDHF pathway to milronone induced vasodilatation and the effect of pertussis toxin.


List of Research Outputs

Ng J.K.F., Changes in thrombelastograph variables associated with aging, Anesthesia and Analgesia. USA, 2004, 99: 449-454.
Ng J.K.F., Coagulation Monitoring in the Operating Theatre, Combined Scientific Meeting in anaesthesiology 2004, Hong Kong College of Anaesthesiologists. HK, 2004, Nov: 12-14.
Ng J.K.F., In: Management of acute pain, Doctor's Magazine 2004. 2004.
Ng J.K.F., Vanhoutte P.M.G.R. and Man R.Y.K., The role of pertussis toxin sensitive pathways in EDHF mediated relaxation in porcine coronary arteries, Mechanisms of vasodilatation & EDHF 2005. Belgium, Antwerp, S20, p17.
Tsui S.L., Yong B.H., Ng J.K.F., Yuen T.S.T., Li C.F. and Chui K.Y., Delayed epidural catheter removal: the impact of postoperative coagulopathy, Anesthesia and Intensive Care. Australia, 2004, 32: 630-636.


Researcher : Rodrigo MRC

Project Title:A study to evaluate the usefulness of BIS in conscious sedation with midazolam
Investigator(s):Rodrigo MRC
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:11/2002
Completion Date:10/2004
Abstract:
To find out (a) whether conscious sedation with midazolam could be carried out using BIS values as indicators of the degree of sedation; (b) whether the degree of amnesia during surgery under midazolam sedation could be predicted with the BIS values recorded during surgery and (c) whether BIS values could be used for fitness of discharge of patients after midazolam sedation.


List of Research Outputs

Rodrigo M.R.C., Case Report: Malignant Hyperthermia in a Dental Student undergoing Dental surgery, Annual Summer Meeting of the Association of Dental Anaesthetists of UK, Oxford. UK, 2004.


Researcher : Sun NCH

List of Research Outputs

Sun N.C.H., Wong A.Y.C. and Irwin M.G., A comparison of pain on intravenous injection between two preparations of propofol, Anesthesia and Analgesia. USA, 2005, 101 (3): 675-678.


Researcher : Tsui SL

List of Research Outputs

Tsui S.L., Yong B.H., Ng J.K.F., Yuen T.S.T., Li C.F. and Chui K.Y., Delayed epidural catheter removal: the impact of postoperative coagulopathy, Anesthesia and Intensive Care. Australia, 2004, 32: 630-636.


Researcher : Wong AYC

List of Research Outputs

Sun N.C.H., Wong A.Y.C. and Irwin M.G., A comparison of pain on intravenous injection between two preparations of propofol, Anesthesia and Analgesia. USA, 2005, 101 (3): 675-678.
Wong A.Y.C., Chan R.S.N. and Irwin M.G., Anaethetic management of caesarean delivery in a patient with hypoplastic anaemia and severe preeclampsia, Canadian Journal of Anesthesiology. Canada, 2004, 51: 923-927.
Wong A.Y.C. and Irwin M.G., Large venous air embolism in the sitting position despite monitoring with transoesophageal echocardiography, Anaesthesia. UK, 2005, 60 (8): 811-813.


Researcher : Yong BH

List of Research Outputs

Liu C.L., Fan S.T., Lo C.M., Wei W.I., Chan S.C., Yong B.H., Lai C.L. and Wong J., Operative outcomes of adult-to-adult right lobe live donor liver transplantation: a comparative study with cadaveric whole-graft liver transplantation in a single center (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004.
Liu C.L., Fan S.T., Lo C.M., Chan S.C., Yong B.H. and Wong J., Safety of donor right hepatectomy without abdominal drainage: a prospective evaluation in 100 consecutive liver donors, Liver Transplantation. 2005, 11(3): 314-319.
Lo C.M., Fan S.T., Liu C.L., Yong B.H., Wong Y., Lau G., Lai C.L., Ng I.O.L. and Wong J., Lessons learned from one hundred right lobe living donor liver transplants, Annals of Surgery. 2004, 240(1): 151-158.
Tsui S.L., Yong B.H., Ng J.K.F., Yuen T.S.T., Li C.F. and Chui K.Y., Delayed epidural catheter removal: the impact of postoperative coagulopathy, Anesthesia and Intensive Care. Australia, 2004, 32: 630-636.


Researcher : Yuen TST

List of Research Outputs

Tsui S.L., Yong B.H., Ng J.K.F., Yuen T.S.T., Li C.F. and Chui K.Y., Delayed epidural catheter removal: the impact of postoperative coagulopathy, Anesthesia and Intensive Care. Australia, 2004, 32: 630-636.
Yuen T.S.T. and Irwin M.G., The "fifth vital sign", Hong Kong Medical Journal. HK, 2005, 11 (3): 145-146.


Researcher : Yuen VMY

List of Research Outputs

Yuen V.M.Y., Chow B.F.M. and Irwin M.G., Severe hypotension and hepatic dysfunction in a patient undergoing scoliosis surgery in the prone position, Anaesthesia Intensive Care. Australia, 2005, 33 (3): 393-399.


Researcher : Zhang Y

List of Research Outputs

Zhang Y., Irwin M.G. and Wong T.M., Remifentanil Preconditioning Protects against Ischemic Injury in the Intact Rat Heart, Anesthesiology. USA, 2004, 101: 918-923.
Zhang Y., Zhang Y., Irwin M.G. and Wong T.M., Remifentanil mimics the cardioprotective effect of ischemic preconditioning via protein kinase C activation in open chest rats, Acta Pharmacologica Sinica. 2005, 26: 546-550.
Zhang Y., Irwin M.G., Wong T.M., Chen M. and Cao C., Remifentanil preconditioning confers cardioprotection via cardiac kappa- and delta-opioid receptors, Anesthesiology. USA, 2005, 102: 371-378.


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