DENTAL FACULTY - ORAL BIOSCIENCES
| Researcher : Bandara HMHN |
| List of Research Outputs |
| Bandara H.M.H.N., Cheung B.P.K., Watt R.M., Jin L. and Samaranayake L.P., Pseudomonas aeruginosa lipopolysaccharide inhibits Candida albicans hyphae formation and alters gene expression during biofilm development, Molecular Oral Microbiology. 2013, 28: 54-69. |
| Samaranayake Y.H., Bandara H.M.H.N., Cheung B.P.K., Yau J.Y.Y., Yeung S.K.W. and Samaranayake L.P., Enteric gram-negative bacilli suppress Candida biofilms on Foley urinary catheters, APMIS : acta pathologica, microbiologica et immunologica Scandinavica. 2013. |
| Researcher : Chen W |
| List of Research Outputs |
| Choi M.Y., Wang Y., Wong L.L.Y., Lu B., Chen W., Huang J., Tanner J.A. and Watt R.M., The Two PPX-GppA Homologues from Mycobacterium tuberculosis Have Distinct Biochemical Activities, PLoS ONE. 2012, 7(8): e42561. |
| Watt R.M. and Chen W., Faculty Research Output Prize (2012), Faculty of Dentistry. 2012. |
| Researcher : Choi MY |
| List of Research Outputs |
| Choi M.Y., Wang Y., Wong L.L.Y., Lu B., Chen W., Huang J., Tanner J.A. and Watt R.M., The Two PPX-GppA Homologues from Mycobacterium tuberculosis Have Distinct Biochemical Activities, PLoS ONE. 2012, 7(8): e42561. |
| Researcher : Jung HS |
| Project Title: | Development and regeneration; Implications for total and partial reconstruction of the tooth by dental mesenchymal progenitor cells |
| Investigator(s): | Jung HS |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2013 |
| List of Research Outputs |
| Cho Y.C., Cha J.Y., Hwang C.J., Park Y.C., Jung H.S. and Yu H.S., Biologic stability of plasma ion-implanted miniscrews, Korean Journal of Orthodontics. 2013, 43(3): 120-6. |
| Jami J., Gadi J., Lee M.J., Kim E.J., Lee M.J., Jung H.S., Kim H.H. and Lim S.K., Pax6 expressed in osteocytes inhibits canonical Wnt signaling, Molecules and Cells. 2013, 35(4): 305-12. |
| Jung H.S., " Regeneration of tooth: Biotooth", 24th Congress of the International Association of Paediatric Dentistry / Korea. 2013. |
| Jung H.S., "Dental Pulp Regeneration: from bench-top to clinic", The 9th World Endodontic Congress / Japan. 2013. |
| Jung H.S., "Generating Yap and Taz Defiant mice", 11th International Conference on Tooth Morphogenesis and Differentiation / France. 2013. |
| Jung H.S., "Shh and 5E1 In Tooth Morphogenesis", Wuhan University, Faculty of Dentistry, Graduate Seminar / China. 2013. |
| Jung H.S., "Shh and 5E1 in tooth development", 2013 Kyushu Dental Symposium / Japan. 2013. |
| Jung H.S., "Stem cells in Gerbil incisor", The 118th Annual Meeting of the Japanese Association of Anatomists / Japan. 2013. |
| Jung H.S., "Tooth Development and Regeneration", Beijing Capital Medical School, Graduate Seminar / China. 2013. |
| Kim E.J., Cho S.W., Shin J.O., Lee M.J., Kim K.S. and Jung H.S., Ihh and Runx2/Runx3 signaling interact to coordinate early chondrogenesis: a mouse model, PLoS One. 2013, 8(2): e55296. |
| Kim E.J. and Jung H.S., Pleiotropic functions of fibroblast growth factor signaling in embryonic mammary gland development, Journal of Mammary Gland Biology and Neoplasia. 2013, 18(2): 139-42. |
| Lee J.M., Kim E.J. and Jung H.S., A method for electroporation to study gene function in mammary gland development, Journal of Mammary Gland Biology and Neoplasia. 2013, 18(2): 233-7. |
| Lee J.M., Lee D.J., Bae S.C. and Jung H.S., Abnormal liver differentiation and excessive angiogenesis in mice lacking Runx3, Histochemistry and Cell Biology. 2013, 139(5): 751-8. |
| Lee M.J., Yoon K.S., Cho K.W., Kim K.S. and Jung H.S., Expression of miR-206 during the initiation of mammary gland development, Cell Tissue Research. 2013. |
| Lee M.J., Shin J.O. and Jung H.S., Thy-1 knockdown retards wound repair in mouse skin, Journal of Dermatological Science. 2013, 69(2): 95-104. |
| Song J.S., Hwang D.H., Kim S.O., Jeon M., Choi B.J., Jung H.S., Moon S.J., Park W. and Choi H.J., Comparative gene expression analysis of the human periodontal ligament in deciduous and permanent teeth, PLoS One. 2013, 8(4): e61231. |
| Researcher : Mo S |
| List of Research Outputs |
| Leung W.K., You M., Mo S. and Watt R.M., Best Paper Award in Microbiology / Immunology / Periodontal Research, 26th IADR-SEA Annual Scientific Meeting. 2012. |
| Leung W.K., You M., Mo S. and Watt R.M., Oral Treponeme Phylotypes Associated with Health and Disease, 26th IADR-SEA Annual Scientific Meeting, Hong Kong. 2012. |
| Mo S., You M., Su Y.C.F., Lacap-Bugler D.C., Huo Y., Smith G.J.D., Leung W.K. and Watt R.M., Multilocus sequence analysis of Treponema denticola strains of diverse origin, BMC Microbiology. 2013, 13:24: (doi:10.1186/1471-2180-13-24). |
| Mo S., You M., Gao W., Huo Y., Leung W.K. and Watt R.M., Phylogenetic Relationships Between Treponema putidum and Treponema denticola Isolates, International Association for Dental Research Pan European Regional Meeting (IADR/PER), Helsinki, Finland. 2012. |
| You M., Mo S., Leung W.K. and Watt R.M., Comparative analysis of oral treponemes associated with periodontal health and disease, BMC Infectious Diseases. 2013, 13:174. |
| Researcher : Samaranayake YH |
| Project Title: | 84th General Session and Exhibition of the International Association for Dental Research (IADR) Synergistic Effect of Lysozyme and Amphotericin B on Candida Biofilms |
| Investigator(s): | Samaranayake YH |
| Department: | Dental Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2006 |
| List of Research Outputs |
| Samaranayake Y.H., Cheung B.P.K., Yau J.Y.Y., Yeung S.K.W. and Samaranayake L.P., Characteristics of Candida biofilms on Catheter Surfaces, IADR General Session, Iguacu, Falls, Brazil, 18-23 June. 2012, 1549. |
| Samaranayake Y.H., Bandara H.M.H.N., Cheung B.P.K., Yau J.Y.Y., Yeung S.K.W. and Samaranayake L.P., Enteric gram-negative bacilli suppress Candida biofilms on Foley urinary catheters, APMIS : acta pathologica, microbiologica et immunologica Scandinavica. 2013. |
| Samaranayake Y.H., Cheung B.P.K., Wang Y., Yau J.Y.Y., Yeung S.K.W. and Samaranayake L.P., Fluconazole resistance in Candida glabrata is associated with increased bud formation and metallothionein production., Journal of Medical Microbiology. 2013, 62(Pt 2): 303-318. |
| Samaranayake Y.H., Cheung B.P.K., Yau J.Y.Y., Yeung S.K.W. and Samaranayake L.P., Human Serum Promotes Candida albicans Biofilm growth and Virulence Gene Expression on Silicone Biomaterial, PLoS One. 2013, 8(5):e62902. |
| Researcher : Seneviratne CJ |
| Project Title: | Multiplex PCR array for detection and quantification of caries associated bacteria |
| Investigator(s): | Seneviratne CJ, Lo ECM, Samaranayake LP, Gao X |
| Department: | Dental Faculty |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 11/2010 |
| Completion Date: | 10/2012 |
| Project Title: | Structure-Activity Relationship of Novel Antifungal Small molecule against Candida |
| Investigator(s): | Seneviratne CJ, Kao RYT, Wang Y, Samaranayake LP |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2011 |
| Completion Date: | 04/2013 |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Seneviratne CJ |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 12/2011 |
| Project Title: | IADR General Session & Exhibition; Metagenomic analysis of Giant Panda (Ailuropoda melanoleuca) dental plaque microbiome |
| Investigator(s): | Seneviratne CJ |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 03/2013 |
| List of Research Outputs |
| Chen Y., Wong R.W.K., Seneviratne C.J., Hagg E.U.O., McGrath C.P.J., Samaranayake L.P., Burns E. and Goh S.H., Comparison of antimicrobial effect between triclosan toothpaste and nano-silver toothpaste, International Dental Journal. 2012, 62 (Suppl. 1): 18. |
| Chen Y., Wong R.W.K., Seneviratne C.J., Hagg E.U.O. and McGrath C.P.J., Effects of a Chinese Medicine and Essential Oils Mouthrinses on Patients with Fixed Orthodontic Appliances, The 88th Congress of the European Orthodontic Society in Santiago de Compostela, Spain, 18 - 23 June, 2012. |
| Gao X., Seneviratne C.J., Lo E.C.M., Chu C.H. and Samaranayake L.P., Novel and conventional assays in determining abundance of Streptococcus mutans in saliva, International Journal of Paediatric Dentistry. 2012, 22(5): 363-8. |
| Gao X., Seneviratne C.J., Lo E.C.M., Chu C.H. and Samaranayake L.P., Novel S. Mutans detection system in predicting early childhood caries, Journal of Dental Research. 2013, 92 (Spec Iss A): 2604. |
| Herath M.T.D.K.H., Wang Y., Seneviratne C.J., Darveau R.P., Wang C.Y. and Jin L., Porphyromonas gingivalis LPS regulates MnSOD in HGFs through TLR4-NF-kB pathway, Journal of Dental Research. 2012, 91 (Spec Iss C): 169737 (SEA Division). |
| Herath Mudiyanselage T.D.K.H., Darveau R.P., Seneviratne C.J., Wang C.Y., Wang Y. and Jin L., Tetra- and Penta-Acylated Lipid A Structures of Porphyromonas gingivalis LPS Differentially Activate TLR4-Mediated NF-kB Signal Transduction Cascade and Immuno-Inflammatory Response in Human Gingival Fibroblasts, PLoS One. 2013, 8: e58496. |
| LI H., Seneviratne C.J., Wang C.Y. and Jin L., 2011 International Association for Dental Research (IADR) - South East Asia Division /Unilever Hatton Divisional Award (Senior category), SHong Kong (Primary Supervisor for Ms. H.J. Li, a PhD student) , IADR - Southeast Asian Division. 2012. |
| Li H., Seneviratne C.J., Lau A.S.Y., Wang C.Y. and Jin L., Commensals and periodontopathogens modulate immuno-inflammatory trajectories in HOKs and THP-1, Journal of Dental Research. 2012, 91 (Spec Iss C): 169577 (SEA Division). |
| Li H., Seneviratne C.J., Lau A.S.Y., Wang C.Y. and Jin L., Commensals and periodontopathogens modulate immuno-inflammatory trajectories in HOKs and THP-1, Journal of Dental Research. 2013, 92 (Spec Iss A): 2285. |
| Seneviratne C.J., Gao X., Jin L., Samaranayake L.P., Bridges S.M. and Lo E.C.M., Enhancing secondary school students' science concepts using dental examples, Journal of Dental Research. 2012, 91 (Spec Iss C): 169674 (SEA Division). |
| Seneviratne C.J., Lok S., Tong A., Kot S., Chan T.F., Martelli P., Samaranayake L.P. and Jin L., Metagenomic analysis of Giant Panda (Alluropoda melanoleuca) dental plaque microbiome, Journal of Dental Research. 2013, 92 (Spec Iss A): 62. |
| Seneviratne C.J., Understanding Microbial Biofilms: Stiill Scratching the Surface, Faculty of Dentistry, UBC, Vancouver, Canada. 2012. |
| Researcher : Tsang WK |
| Project Title: | Generation of focused libraries by combinatorial biocatalysis with anti-Candidal activity: synthesis and in vitro study |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Mini Grants |
| Start Date: | 01/2009 |
| Project Title: | From vital to lethal: functional analysis of apoptosis-inducing factor in the human fungal pathogen Candida albicans |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Mini Grants |
| Start Date: | 12/2011 |
| Project Title: | Investigation of the functional significance of phytase activity in Candida albicans: gene disruption, pH regulation, and virulence study |
| Investigator(s): | Tsang WK, Samaranayake LP |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 03/2012 |
| Project Title: | Perturbation of pH homeostasis: a comparative study on the inhibitory effect of purpurin on membrane-bound ATPases in Candida albicans |
| Investigator(s): | Tsang WK, Samaranayake LP |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Project Title: | Construction of "arming yeast" for cell surface display of phytase |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2013 |
| List of Research Outputs |
| Tsang W.K., Bandara H.M.H.N. and Fong W.P., Purpurin suppresses Candida albicans biofilm formation and hyphal development, PLoS ONE. The United States of America, 2012, 7: e50866. |
| Tsang W.K., Bandara H.M.H.N., Samaranayake L.P., Tsang P.C.S. and Fong W.P., Purpurin-induced changes in the proteome of Candida albicans, 26th International Association for Dental Research South-East Asia Division. 2012. |
| Tsang W.K., Bandara H.M.H.N., Samaranayake L.P., Tsang P.C.S. and Fong W.P., Purpurin-induced changes in the proteome of Candida albicans, Journal of Dental Research. 2012, 91 (Special Issue C): 168913. |
| Tsang W.K., Bandara H.M.H.N. and Fong W.P., Research Output Prize 2013, Faculty of Dentistry, The University of Hong Kong. 2013. |
| Researcher : Watt RM |
| Project Title: | Genes get 'recT' : new and improved methods for bacterial DNA engineering |
| Investigator(s): | Watt RM, Huang J, Tanner JA |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | New approaches for the analysis of microbial biofilms associated with periodontal disease |
| Investigator(s): | Watt RM, Leung WK |
| Department: | Dental Faculty |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| Project Title: | Treponema denticola and periodontal disease: novel analytical approaches to probe host-pathogen relationships |
| Investigator(s): | Watt RM, Leung WK, Tanner JA |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2012 |
| Project Title: | Stress response in the oral pathogen Fusobacterium nucleatum: the interplay between polyphosphate metabolism and the stringent response |
| Investigator(s): | Watt RM, Seneviratne CJ, Choi MY |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2012 |
| Project Title: | Raising the alarmone in Staphylococcus aureus: establishing the molecular basis of the stringent response |
| Investigator(s): | Watt RM, Seneviratne CJ, Tanner JA |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Watt RM |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 01/2013 |
| Project Title: | Molecular analysis of Synergistetes communities associated with chronic and aggressive forms of periodontitis |
| Investigator(s): | Watt RM, Leung WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2013 |
| List of Research Outputs |
| Bandara H.M.H.N., Cheung B.P.K., Watt R.M., Jin L. and Samaranayake L.P., Pseudomonas aeruginosa lipopolysaccharide inhibits Candida albicans hyphae formation and alters gene expression during biofilm development, Molecular Oral Microbiology. 2013, 28: 54-69. |
| Choi M.Y., Wang Y., Wong L.L.Y., Lu B., Chen W., Huang J., Tanner J.A. and Watt R.M., The Two PPX-GppA Homologues from Mycobacterium tuberculosis Have Distinct Biochemical Activities, PLoS ONE. 2012, 7(8): e42561. |
| GAO W., YOU M., Lang N.P., Leung W.K. and Watt R.M., Diversity of Treponema and Synergistetes phylotypes in equine subgingival plaque, J Dent Res 91 (Spec Iss C):169796 (SEA Division). 2012. |
| Leung W.K., You M., Mo S. and Watt R.M., Best Paper Award in Microbiology / Immunology / Periodontal Research, 26th IADR-SEA Annual Scientific Meeting. 2012. |
| Leung W.K., You M., Mo S. and Watt R.M., Oral Treponeme Phylotypes Associated with Health and Disease, 26th IADR-SEA Annual Scientific Meeting, Hong Kong. 2012. |
| Mo S., You M., Su Y.C.F., Lacap-Bugler D.C., Huo Y., Smith G.J.D., Leung W.K. and Watt R.M., Multilocus sequence analysis of Treponema denticola strains of diverse origin, BMC Microbiology. 2013, 13:24: (doi:10.1186/1471-2180-13-24). |
| Mo S., You M., Gao W., Huo Y., Leung W.K. and Watt R.M., Phylogenetic Relationships Between Treponema putidum and Treponema denticola Isolates, International Association for Dental Research Pan European Regional Meeting (IADR/PER), Helsinki, Finland. 2012. |
| Watt R.M., Editorial Board Member, Oral Biology and Dentistry. Herbert Publications, 2013. |
| Watt R.M. and Chen W., Faculty Research Output Prize (2012), Faculty of Dentistry. 2012. |
| Watt R.M., Oral Spirochete Bacteria and the Etiology of Periodontal Disease: an Evolving Story, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand. 2013. |
| Watt R.M., Oral Spirochetes: Diversity and disease, Institute of Dentistry, University of Helsinki, Finland. 2012. |
| Watt R.M., The Etiology of Periodontal Disease: Are Chinese Treponemes More Dangerous Than American Ones?, Postgraduate School of Oral Health Sciences (PeGaSOS) Institute of Dentistry, University of Turku, Finland. 2012. |
| Watt R.M., The Twists and Turns of Periodontal Microbiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. 2013. |
| Watt R.M., YOU M. and Leung W.K., Treponeme major surface protein (msp) genotypes associated with periodontitis, J Dent Res 92(Spec Iss A):60, 2013. Abstract# 2265. |
| You M., Mo S., Leung W.K. and Watt R.M., Comparative analysis of oral treponemes associated with periodontal health and disease, BMC Infectious Diseases. 2013, 13:174. |
| You M., Mo S., Watt R.M. and Leung W.K., Prevalence and diversity of Synergistetes taxa in periodontal health and disease, Journal of Periodontal Research. John Wiley & Sons, 2012, 48 (2): 159-168. |
| ZHENG S., YU B., ZHANG K., Chen M., HUA Y., YUAN S., Watt R.M., Zheng B., Yuen K.Y. and Huang J., Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines, BMC Immunology. 2012, 13:54. |
| ZHUANG L., Watt R.M., Wang R., LANG-HUA B.H., Steiner S., Ramseier C.A. and Lang N.P., Microbiological characteristics of Sri Lankan tea-laborers without oral hygiene performance, J Dent Res 91 (Spec Iss C):168829 (SEA Division). 2012. |
| ZHUANG L., Watt R.M., Wang R., LANG-HUA B.H., Ramseier C.A. and Lang N.P., Subgingival Microbiota Related to Pocket Probing Depth in Sri-Lankan Tea-Laborers, J Dent Res 92(Spec Iss A):60, 2013. |