DEPT OF PAEDIATRICS & ADOLESCENT MED
Researcher : CHEN J |
List of Research Outputs |
CHEN J., LEE V., Luo J.C., Chiang A.K.S., Hongeng S., Tan P.L., Tan A.M., Sanpakit K., Li C.F., Lee A.C., Chua H.C. and Okamoto Y., Allogeneic stem cell transplantation for children with acquired severe aplastic anaemia: a retrospective study by the Viva-Asia Blood and Marrow Transplantation Group, British Journal of Haematology. 2013, 162(3). |
Researcher : Chan GCF |
Project Title: | Treatment protocol for childhood medulloblastoma in Hong Kong |
Investigator(s): | Chan GCF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Other Funding Scheme |
Start Date: | 01/2001 |
Project Title: | Review of local experience in the management of childhood myelodysplastic syndrome |
Investigator(s): | Chan GCF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Other Funding Scheme |
Start Date: | 01/2001 |
Project Title: | Survey on the prevalence on use of alternative medical treatment in paediatric patients |
Investigator(s): | Chan GCF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Other Funding Scheme |
Start Date: | 09/2001 |
Project Title: | Direct generation and functional characterization of human dendritic cells derived from bone marrow cells of leukemic origins |
Investigator(s): | Chan GCF, Chiu CSW, Ma ESK, Huang F |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Other Funding Scheme |
Start Date: | 07/2002 |
Project Title: | King's/HKU Fellowship Awards 2009-10 |
Investigator(s): | Chan GCF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | King's/HKU Fellowship Awards |
Start Date: | 09/2009 |
Project Title: | The immunomodulatory effect of artepillin C (Art-C) in experimental autoimmune encephalitis murine models |
Investigator(s): | Chan GCF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 06/2013 |
Project Title: | Recent Advances in Health and Medical Sciences (4th RAHMS) International Conference; IRON OVERLOAD CAN SUPPRESS DENDRITIC CELLS FUNCTION IN VITRO |
Investigator(s): | Chan GCF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 06/2013 |
List of Research Outputs |
Chan G.C.F., Common haematological illness in childhood, CME Lecture for the Association of Licentiate medical Certificate of Hong Kong, Hong Kong. 2012. |
Chan G.C.F., Editorial on "Manpower crisis in Paediatrics", Hong Kong Journal of Paediatrics. 2012, 17(3): 141-142. |
Chan G.C.F., Stem cell therapy: the myth and the reality, Annual Meeting of the Hong Kong College of Paediatrician Foundation, Hong Kong. 2012. |
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Health-Related Quality of Life in Children who Survive after Cancer Therapy, 19th Hong Kong International Cancer Congress, Nov 8-9, 2012, Hong Kong. 2012. |
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Malignancies in Chinese patients with neurofibromatosis type 1, Hong Kong Medical Journal. 2013, 19: 42-49. |
Cheung Y.F., Yu W., Li S.N., Lam W.W.M., Ho Y.C., Wong S.J., Chan G.C.F. and Ha S.Y., Dynamic dyssynchrony and impaired contractile reserve of the left ventricle in beta-thalassaemia major: an exercise echocardiographic study , PLOS One . 2012, 7: e45265. |
Chow C.B., Ip P., Wong R.M.S. and Chan G.C.F., Submission to Panel on Health Services on the regulation of formula products and foods for infants and young children. Letter of recommendations to Hong Kong Legislative Council, LC Paper No. CB(2)213/12-13(03), Legislative Council, Hong Kong, 20 November 2012., 2012. |
Diao H., Yan C.H., Chan G.C.F. and Chan B.P., Interactions between human mesenchymal stem cells and human osteoarthritic chondrocytes in 3D co-cultures, Regenerative Medicine . 2013, 8(3): 257-269. |
HONG Y., Chan G.C.F. and Sun H., Interaction of bismuth with proximal tubular cell and hepatcyte, 6th Asian Biological Inorganic Chemistry . 2012. |
HONG Y., Chan G.C.F. and Sun H., Interaction of bismuth with proximal tubular cell and hepatcyte, 6th Asian Biological Inorganic Chemistry (AsBIC-VI). 2012. |
Robles J.D., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Norovirus infection in pediatric hematopoietic stem cell transplant recipients: incidence, risk factors and outcome, Biology of Blood and Marrow Transplant. 2012, in press. |
Surapolchai P., Ha S.Y., Chan G.C.F., Lukito J.B., Wan T.S.K., So J.C.C. and Chiang A.K.S., Central Diabetes Insipidus: An Unusual Complication in a Child With Juvenile Myelomonocytic Leukemia and Monosomy 7, Journal of Pediatric Hematology and Oncology. 2013, 35: e84-e87. |
Tong W.Y.T., Shen W., Lam Y.W., Zhao Y., Cheng S.H., Chu P.K., Chan D., Chan G.C.F., Cheung K.M.C. and Yeung K.W.K., Functionally Replicated Bioimprint Scaffold to Support Tenocytic Differentiation of Mesenchymal Stem Cells, Orthopaedic Research Society (ORS) Annual Meeting, San Antonio, Texas, USA. 2013. |
Tong W.Y.T., Shen W., Zhao Y., Cheng S.H., Chu P.K., Chan D., Chan G.C.F., Cheung K.M.C., Yeung K.W.K. and Lam Y.W., Tenogenic Differentiation of Human Mesenchymal Stem Cells on Novel Bio-Imprinted Scaffolds, 15th International Biotechnology Symposium and Exhibition (IBS 2012), Daegu, South Korea. 2012. |
Tsang J.S., Tong D.K.H., Chung B.H.Y., Tang M.H.Y., Lau E.T.K., Chan G.C.F. and Law S.Y.K., Alport's syndrome: case of a giant esophageal tumor [Doi:10.1007/s10388-012-0355-3], Esophagus. Springer, 2013, 10: 114-117. |
Xiong H., Ha S.Y., Chiang A.K.S., Hu Q. and Chan G.C.F., A small cohort review of the long-term prognosis for Chinese older children and adolescents with acute lymphoblastic leukaemia treated on a paediatric protocol, Hong Kong Journal of Paediatrics (new series). 2013, 18: 89-95. |
Yang J., Cheuk K.L.D., Ha S.Y., Chiang A.K.S., Lee T.L., Ho M.H.K. and Chan G.C.F., Infliximab for steroid refractory or dependent gastrointestinal acute graft-versus-host disease in children after allogeneic hematopoietic stem cell transplantation, Pediatr Transplant. 2012, 16(7): 771-8. |
Yu H.K., Yu W., Cheuk K.L.D., Wong S.J., Chan G.C.F. and Cheung Y.F., New 3D speckle tracking echocardiography identifies global impairment of left ventricular mechanics with a high sensitivity in childhood cancer survivors , J Am Soc Echocardiogr. 2013, 26: 846-52. |
Yu W., Li S., Chan G.C.F., Ha S.Y., Wong S.J. and Cheung Y.F., Transmural strain and rotation gradient in survivors of childhood cancers, European Heart Journal Cardiovascular Imaging . 2012, 14: 175-182. |
Researcher : Chan KW |
List of Research Outputs |
Chow P.C., Chan K.W., Lun K.S., Yung T.C., Cheung Y.F. and Chau A.K.T., Outcome of pregnancy in women with congential heart diseases (CHD) of a tertiary centre in Hong Kong, 21st Annual Scientific Scientific Congress, Hong Kong College of Cardiology, 8 June 2013. |
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L. and Lau Y.L., Autosomal Dominant Gain-of-function STAT1 Mutation is a Novel Genetic Etiology of Penicillium Marneffei Infection , Asian Society for Pediatric Research 2013. |
Lee P.P.W., He J.X., Chan K.W., Yang W., Jiang L.P., Liew W.K., Chen T.X., Ho M.H.K., Lee T.L. and Lau Y.L., Unique Pattern of Infections in Chronic Granulomatous Disease – The Asian Experience, Asian Society for Pediatric Research 2013. |
Researcher : Chan SHS |
List of Research Outputs |
Chan S.H.S., Wong V.C.N. and Engel A.G., Neuromuscular junction acetylcholinesterase deficiency responsive to albuterol, Pediatric Neurology. 2012, 47(2): 137-140. |
Researcher : Chan SY |
Project Title: | Role of the nucleosome assembly protein TSPY-like 2 in cell cycle control upon DNA damage |
Investigator(s): | Chan SY, Ching YP |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 02/2011 |
Completion Date: | 02/2013 |
Project Title: | Behavioural phenotyping of a mouse model with social dysfunction |
Investigator(s): | Chan SY, Li Q |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Seed Funding Programme for Basic Research |
Start Date: | 05/2012 |
Project Title: | Effect of the nucleosome assembly protein Tspyl2 in building the epigenetic landscape |
Investigator(s): | Chan SY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 06/2013 |
List of Research Outputs |
Don-Salu-Hewage A.S., Chan S.Y., McAndrews K.M., Chetram M.A., Dawson M.R., Bethea D.A. and Hinton C.V., Cysteine (C)-X-C Receptor 4 Undergoes Transportin 1-Dependent Nuclear Localization and Remains Functional at the Nucleus of Metastatic Prostate Cancer Cells, PLOS One. 2013, 8(2): e57194. |
Eda T., Mizuno M., Araki K., Iwakura Y., Namba H., Sotoyama H., Kakita A., Takahashi H., Satoh H., Chan S.Y. and Nawa H., Neurobehavioral deficits of epidermal growth factor-overexpressing transgenicmice: Impact on dopamine metabolism, Neurosciences Letter . Elsevier, 2013, 547: 21-25. |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Kwong K.Y., Fung C.W., Chan S.Y. and Wong V.C.N., Identification of SCN1A and PCDH19 Mutations in Chinese Children with Dravet Syndrome, PLoSOne. 2012, 7(7): e41802. |
Man E., Lafferty K.A., Funke B.H., Lun K.S., Chan S.Y., Chau A.K.T. and Chung B.H.Y., NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy, BMJ Case Reports [doi:10.1136/bcr-2012-007529]. 2013. |
Researcher : Chan SY |
List of Research Outputs |
Don-Salu-Hewage A.S., Chan S.Y., McAndrews K.M., Chetram M.A., Dawson M.R., Bethea D.A. and Hinton C.V., Cysteine (C)-X-C Receptor 4 Undergoes Transportin 1-Dependent Nuclear Localization and Remains Functional at the Nucleus of Metastatic Prostate Cancer Cells, PLOS One. 2013, 8(2): e57194. |
Eda T., Mizuno M., Araki K., Iwakura Y., Namba H., Sotoyama H., Kakita A., Takahashi H., Satoh H., Chan S.Y. and Nawa H., Neurobehavioral deficits of epidermal growth factor-overexpressing transgenicmice: Impact on dopamine metabolism, Neurosciences Letter . Elsevier, 2013, 547: 21-25. |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Kwong K.Y., Fung C.W., Chan S.Y. and Wong V.C.N., Identification of SCN1A and PCDH19 Mutations in Chinese Children with Dravet Syndrome, PLoSOne. 2012, 7(7): e41802. |
Man E., Lafferty K.A., Funke B.H., Lun K.S., Chan S.Y., Chau A.K.T. and Chung B.H.Y., NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy, BMJ Case Reports [doi:10.1136/bcr-2012-007529]. 2013. |
Researcher : Chau AKT |
List of Research Outputs |
Chow P.C., Chan K.W., Lun K.S., Yung T.C., Cheung Y.F. and Chau A.K.T., Outcome of pregnancy in women with congential heart diseases (CHD) of a tertiary centre in Hong Kong, 21st Annual Scientific Scientific Congress, Hong Kong College of Cardiology, 8 June 2013. |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Man E., Lafferty K.A., Funke B.H., Lun K.S., Chan S.Y., Chau A.K.T. and Chung B.H.Y., NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy, BMJ Case Reports [doi:10.1136/bcr-2012-007529]. 2013. |
Researcher : Chau CSK |
List of Research Outputs |
Chau C.S.K. and Lee S.L., Successful use of BiPAP in infants with congenital myotonic dystrophy, Pediatrics International. 2013, 55(2): 243-245. |
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318. |
Researcher : Chen HSR |
List of Research Outputs |
Chen H.S.R., Wong W.H.S. and Cheung Y.F., Vascular mechanics at rest and during exercise after arterial switch operation for complete transposition of the great arteries, Hong Kong College of Cardiology, Twenty-first Annual Scientific Congress, Hong Kong, 7 - 9 June 2013. . 2013. |
Researcher : Cheuk KLD |
List of Research Outputs |
Cheuk K.L.D., Yeung W.F., Chung K.F. and Wong V.C.N., Acupuncture for insomnia, cochrane Database of Systematic Reviews 2012 . 2012, 9: 1-181. |
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Health-Related Quality of Life in Children who Survive after Cancer Therapy, 19th Hong Kong International Cancer Congress, Nov 8-9, 2012, Hong Kong. 2012. |
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Malignancies in Chinese patients with neurofibromatosis type 1, Hong Kong Medical Journal. 2013, 19: 42-49. |
Cheuk K.L.D., Sabin N.D., Hossain M., Wozniak A., Naik M., Rodriguez-Galindo C., Krasin M.J. and Shulkin B.L., PET/CT for staging and follow-up of pediatric nasopharyngeal carcinoma, European Journal of Nuclear Medicine and Molecular Imaging. 2012, 39(7): 1097-1106. |
Cheuk K.L.D., Wong V.C.N., Wraige E., Baxter P. and Cole A., Surgery for scoliosis in Duchenne muscular dystrophy, Cochrane Database of Systematic Reviews. 2013, 2: 1-40. |
Cheuk K.L.D., Transfusion of older blood and risk of death: unanswered questions, Transfusion. 2012, 52(7): 1595-1596. |
Robles J.D., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Norovirus infection in pediatric hematopoietic stem cell transplant recipients: incidence, risk factors and outcome, Biology of Blood and Marrow Transplant. 2012, in press. |
Wong V.C.N., Cheuk K.L.D., Lee S. and Chu L.Y.V., Acupuncture for acute management and rehabilitation of traumatic brain injury, Cochrane Database of Systemic Review. John Wiley & Sons, Ltd., 2013, 3: 1-36. |
Wong V.C.N., Cheuk K.L.D. and Chu L.Y.V., Acupuncture for hypoxic ischemic encephalopathy in neonates, Cochrane Database of Systematic Reviews. 2013, 1: 1-22. |
Yang J., Cheuk K.L.D., Ha S.Y., Chiang A.K.S., Lee T.L., Ho M.H.K. and Chan G.C.F., Infliximab for steroid refractory or dependent gastrointestinal acute graft-versus-host disease in children after allogeneic hematopoietic stem cell transplantation, Pediatr Transplant. 2012, 16(7): 771-8. |
Yu H.K., Yu W., Cheuk K.L.D., Wong S.J., Chan G.C.F. and Cheung Y.F., New 3D speckle tracking echocardiography identifies global impairment of left ventricular mechanics with a high sensitivity in childhood cancer survivors , J Am Soc Echocardiogr. 2013, 26: 846-52. |
Researcher : Cheung PT |
Project Title: | The Endocrine Society 83rd Annual Meeting Mutations of the CYP11B2 Gene in a Patient with Corticosterone Methyl Oxidase Type II Deficiency |
Investigator(s): | Cheung PT |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 06/2001 |
Project Title: | International Perinatal Collegium 2005 Meeting New Approaches in Old Models - Identification of Novel Molecular Alterations in Neonatal Mouse Hypoxic-Ischaemic Brain Damage |
Investigator(s): | Cheung PT |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 07/2005 |
Project Title: | 4th Asian Epigenomics Meeting Methyl mercury induced epigenetic dysregulation of BDNF gene in NG108 cells in vitro – a possible mechanism of environment-epigenome interactions underlying neuropsychiatric and neurodevelopmental disorders. |
Investigator(s): | Cheung PT |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 08/2009 |
Researcher : Cheung YF |
Project Title: | CSX/NKX2.5 mutations in patients with pulmonary atresia and intact ventricular septum |
Investigator(s): | Cheung YF, Chan SY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 11/2003 |
Project Title: | Development of a multimedia tool for teaching of paediatric cardiology |
Investigator(s): | Cheung YF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants |
Start Date: | 04/2004 |
Project Title: | Mechanics of Ventricular-Ventricular Interaction in Patients After Tetralogy of Fallot Repair: Analysis by Three-dimensional Speckle Tracking Echocardiography |
Investigator(s): | Cheung YF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 01/2011 |
Completion Date: | 12/2012 |
Project Title: | Circulating MicroRNA and Right Ventricular Function in Patients After Repair of Tetralogy of Fallot |
Investigator(s): | Cheung YF, Ng EKO |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 02/2011 |
Completion Date: | 01/2013 |
Project Title: | Neo-Aortic Root Stiffness following Arterial Switch Operation: Relationship with Neo-Aortic Root Dilatation and Regurgitation |
Investigator(s): | Cheung YF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 05/2012 |
Project Title: | American College of Cardiology 62th Annual Scientific Session; New Three-dimensional Speckle Tracking Echocardiography Identifies Global Impairment of Left Ventricular Mechanics With a High Sensitivity in Childhood Cancer Survivors |
Investigator(s): | Cheung YF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 03/2013 |
Project Title: | Arterial-Ventriculo-Atrial Interaction in Patients After Surgical Repair of Coarctation of the Aorta |
Investigator(s): | Cheung YF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 06/2013 |
List of Research Outputs |
Chen H.S.R., Wong W.H.S. and Cheung Y.F., Vascular mechanics at rest and during exercise after arterial switch operation for complete transposition of the great arteries, Hong Kong College of Cardiology, Twenty-first Annual Scientific Congress, Hong Kong, 7 - 9 June 2013. . 2013. |
Chen R.H.S., Wong S.J., Wong W.H.S. and Cheung Y.F., Left ventricular contractile reserve after arterial switch operation for complete transposition of the great arteries: an exercise echocardiographic study , European Heart Journal - Cardiovascular Imaging doi:10.1093/ehjci/jes204. 2012, 14(5): 480-486. |
Cheung Y.F., Adverse Cardiovascular Effects of Chemotherapy in Leukemia Survivors, HKPHOSG Annual Scientific Workshop, Hong Kong, Aug 5, 2012. 2012. |
Cheung Y.F., Arterial Function in the Young: Assessment and Clinical Relevance, The 4th Shanghai Symposium on Pediatric Cardiovascular Disease - Outcome of Congenital Heart Disease, Shanghai, Nov 17 - 19 2012. 2012. |
Cheung Y.F., Cardiovascular Surrogate Markers: Their Role in Paediatric Cardiac Outcome Research , The 4th Shanghai Symposium on Pediatric Cardiovascular Disease - Outcome of Congenital Heart Disease, Shanghai, Nov 17 - 19 2012. 2012. |
Cheung Y.F., Circulating annexin A5 levels after atrial switch for transposition of the great arteries: relationship with ventricular deformation and geometry., PLOS One . 2012, 7: e52125 doi:10.1371/journal.pone.0052125. |
Cheung Y.F., Clopidogrel in Infants with Systemic-to-Pulmonary-Artery Shunts (Contributor), The New England Journal of Medicine. 2013, 368(25): 2377-2384. |
Cheung Y.F., Yu W., Li S.N., Lam W.W.M., Ho Y.C., Wong S.J., Chan G.C.F. and Ha S.Y., Dynamic dyssynchrony and impaired contractile reserve of the left ventricle in beta-thalassaemia major: an exercise echocardiographic study , PLOS One . 2012, 7: e45265. |
Cheung Y.F., Echocardiographic assessment of right ventricular function in congenital heart disease: a practical approach, Hong Kong College of Cardiology, 21st Annual Scientific Congress, 7 - 9 June, 2013. 2013. |
Cheung Y.F., Measuring deformation - how much easier or difficult can it get, 6th World Congress Paediatric Cardiology and Cardiac Surgery, Cape Town, South Africa, 17 - 22 February 2013. 2013. |
Cheung Y.F., New echo techniques and functional studies (tissue Doppler/strain/torsion) in congenital heart disease , 19th ASEAN Federation of Cardiology Congress 2012, Singapore, 13-15 July 2012. 2012. |
Cheung Y.F., New echo technqiues and functional studies (tissue doppler / strain / torsion) in congenital heart disease, 19th ASEAN Federation of Cardiology Congress 2012, Singapore 2012. 2012. |
Cheung Y.F., Novel cardiac and vascular imaging in the young , Joint Scientific Meeting, Li Ka Shing Faculty of Medicine, The University of Hong Kong, April 15 2013. . 2013. |
Cheung Y.F., Novel three-dimensional wall motion tracking: potential applications in paediatric cardiac failure , the 9th Korea-Japan-China Pediatric Heart Forum, March 22 to 23, 2013in Gyeongju, Korea. 2013. |
Cheung Y.F., Prevention of adult cardiovascular disease: starting in the Young?, 2013 National Pediatric Cardiology Congress of China, Chengdu, June 18 - 22, 2013. 2013. |
Cheung Y.F., Pulmonary valve replacement after TOF repair. When are the right times? , 6th World Congress Paediatric Cardiology and Cardiac Surgery. Cape Town, South Africa. 17- 22 February 2013. 2013. |
Cheung Y.F., Research Ethics for Biomedical Sciences – Clinical Research Ethics: The Rights of the Human Research Subjects, Li Ka Shing Faculty of Medicine, The Unviersity of Hong Kong, Hong Kong, 18 Dec 2012. , 2012. |
Cheung Y.F., The role of 3D wall motion tracking in heart failure , Nature Review in Cardiology . 2012, 9: 644-657. |
Cheung Y.F., Three-Dimensional and Multi-Layer Speckle Tracking Echocardiography: A Novel Approach to Assess Ventricular Function in the Young, 10th Asia Federation of Societies for Ultrasound in Medicine & Biology (AFSUMB) Workshop, Hong Kong, Aug, 2012. 2012. |
Cheung Y.F., Vasculopathy and cardiomyopathy in thalassaemia major - a new perspective, Thalassaemia Seminar 2013, May 9, 2013. 2013. |
Chow P.C., Chan K.W., Lun K.S., Yung T.C., Cheung Y.F. and Chau A.K.T., Outcome of pregnancy in women with congential heart diseases (CHD) of a tertiary centre in Hong Kong, 21st Annual Scientific Scientific Congress, Hong Kong College of Cardiology, 8 June 2013. |
Koh C., Hong W.J., Yung T.C., Lun K.S., Wong S.J. and Cheung Y.F., Left ventricular torsional mechanics and diastolic function in congenital heart block with right ventricular pacing , International Journal of Cardiology. 2012, 160: 31-35. |
Lee S.L., Cheung Y.F., Wong W.H.S., Leung T.H., Lam T.H. and Lau Y.L., Chronic health problems and health-related quality of life in Chinese children and adolescents: a population-based study in Hong Kong., British Medical Journal Open . 2013, 3: e001183.doi:10.1136/bmjopen-2012-001183. |
Yu H.K., Yu W., Cheuk K.L.D., Wong S.J., Chan G.C.F. and Cheung Y.F., New 3D speckle tracking echocardiography identifies global impairment of left ventricular mechanics with a high sensitivity in childhood cancer survivors , J Am Soc Echocardiogr. 2013, 26: 846-52. |
Yu W., Li S., Chan G.C.F., Ha S.Y., Wong S.J. and Cheung Y.F., Transmural strain and rotation gradient in survivors of childhood cancers, European Heart Journal Cardiovascular Imaging . 2012, 14: 175-182. |
Researcher : Chiang AKS |
Project Title: | Genetic studies of tubercubosis |
Investigator(s): | Chiang AKS |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Other Funding Scheme |
Start Date: | 03/2002 |
Project Title: | Prospective study of virologic and immunologic parameters of primary Epstein-Barr virus infection in Chinese children |
Investigator(s): | Chiang AKS, Chan KH |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 10/2003 |
Project Title: | Prospective study of Epstein-Barr virus (EBV) strains in primary EBV infection |
Investigator(s): | Chiang AKS |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 11/2004 |
Project Title: | Longitudinal study of Epstein-Barr virus specific antibody responses in childhood infectious mononucleosis |
Investigator(s): | Chiang AKS |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 12/2005 |
Project Title: | Investigation of bortezomib in activation of Epstein-Barr virus (EBV) in EBV-associated malignancies |
Investigator(s): | Chiang AKS |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 02/2011 |
Completion Date: | 01/2013 |
Project Title: | Longitudinal study of Epstein-Barr virus-specific T cell immunity in post-transplant lymphoproliferative disorder |
Investigator(s): | Chiang AKS |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 06/2012 |
Project Title: | Investigating the function and maturation of Epstein-Barr virus (EBV)-specific T cell responses in patients with EBV-associated haemophagocytic lymphohistiocytosis |
Investigator(s): | Chiang AKS |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 05/2013 |
List of Research Outputs |
Attarbaschi A., Beishuizen A., Mann G., Mori T., Uyttebroeck A., Niggli F., Csoka M., Krenova Z., Mellgren K., Kabickova E., Reiter A., Williams D., Burkhardt B. and Chiang A.K.S., Children and adolescents with follicular lymphoma have an excellent prognosis with either limited chemotherapy or with a "watch and wait" strategy after complete resection, Annals of Hematology. 2013. |
CHEN J., LEE V., Luo J.C., Chiang A.K.S., Hongeng S., Tan P.L., Tan A.M., Sanpakit K., Li C.F., Lee A.C., Chua H.C. and Okamoto Y., Allogeneic stem cell transplantation for children with acquired severe aplastic anaemia: a retrospective study by the Viva-Asia Blood and Marrow Transplantation Group, British Journal of Haematology. 2013, 162(3). |
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Health-Related Quality of Life in Children who Survive after Cancer Therapy, 19th Hong Kong International Cancer Congress, Nov 8-9, 2012, Hong Kong. 2012. |
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Malignancies in Chinese patients with neurofibromatosis type 1, Hong Kong Medical Journal. 2013, 19: 42-49. |
Chiang A.K.S., Clinical spectrum and biology of Epstein-Barr virus related lymphoproliferative diseases (EB 病毒相關淋巴細胞増殖性疾病的臨床及生物學特性), 2013 National Pediatric Hematology and Cancer Academic Meeting (2013年全國小兒血液與腫瘤學術會議). 2013. |
Chiang A.K.S., Epstein-Barr virus related lymphoproliferative diseases: clinical and biological research, HKU-Shenzhen Hospital. 2013. |
Chiang A.K.S., Investigating Epstein-Barr virus genomic variation in nasopharyngeal carcinoma by next generation sequencing., Cancer 2013 - The Ninth Asia Pacific Multidisciplinary Meeting for Cancer Research, The Chinese University of Hong Kong. 2013. |
Chiang A.K.S., Molecular Mechanisms of Innate Immunity 2013, Hong Kong, 14 Jun, 2013. |
Choi C.K., Ho D.N.Y., Hui K.F., Kao R.Y.T. and Chiang A.K.S., High-thoughput Screening of Small Organic Molecules for Activation of Lytic Cycle of Epstein-Barr Virus (EBV) in EBV-positive Epithelial Malignancies, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 68. |
Ho D.N.Y., Hui K.F., Kao R.Y.T. and Chiang A.K.S., High-thoughput Screening of Small Organic Molecules for Activation of Lytic Cycle of Epstein-Barr Virus (EBV) in EBV-positive Epithelial Maglignancies, 17th Research Postgraduate Symposium, Dec 12 & 13, 2012. 2012. |
Hui K.F., Lam B.H.W., Ho D.N.Y. and Chiang A.K.S., Bortezomib and SAHA Synergistically Induce ROS-driven Casepase-dependent Apoptosis of Nasopharyngeal Carcinoma and Block Replication of Epstein-Barr Virus, 19th Hong Kong International Cancer Congress, Nov 8-9, 2012 Hong Kong . 2012. |
Hui K.F., Lam B.H.W., Ho D.N.Y., Tsao G.S.W. and Chiang A.K.S., Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus, Mol Cancer Ther. 2013, 12: 747-58. |
Hui K.F., Lam B.H., Ho D.N., Tsao G.S.W. and Chiang A.K.S., Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus, Molecular Cancer Therapeutics. 2013, 12(5). |
Hui K.F., Lam B.H.W., Ho D.N.Y. and Chiang A.K.S., Bortezomib combines with suberoylanilide hydroxamic acid (SAHA) to synergistically induce caspase-dependent apoptosis and blocks SAHA's activation of EBV lytic cycle in nasopharyngeal carcinoma, International Congress on Oncogenic Herpesviruses and Associated Diseases, Philadelphia, USA, Aug 1-4, 2012. |
Kwok H., Tong A.H.Y., Lin C., Lok S., Farrell P.J., Kwong D.L.W. and Chiang A.K.S., Genomic Sequencing and Comparative Analysis of Epstein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma Biopsy, 17th Research Postgradute Symposium, Dec 12 & 13, 2012. 2012. |
Kwok H., Tong A.H.Y., Lin C., Lok S., Ferrell P.J., Kwong D.L.W. and Chiang A.K.S., Genomic Sequencing and Comparative Analysis of Epstein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma Biopsy, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 167. |
Kwok H., Tong A.H.Y., Lin C., Lok S., Farrell P.J., Kwong D.L.W. and Chiang A.K.S., Genomic Sequencing and Comparative Analysis of Esptein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma Biopsy, 19th Hong Kong International Cancer Congress - 8-9 Nov 2012, Hong Kong. 2012. |
Leon Y.Y., Hui K.F. and Chiang A.K.S., The Combinatorial Effects of Histone Methyltrasferase Inhibitors with Histone Deacetylase Inhibitors on Epstein-Barr Virus Lytic Cycle Induction in Lymphoid Cells, 17th Research Pstograduate Symposium, Dec 12-13, 2012. 2012. |
Leung Y.Y., Hui K.F. and Chiang A.K.S., The Combinatorial Effects of Histone Methyltrasferase Inhibitors with Histone Deacetylase Inhibitors on Epstein-Barr Virus Lytic Cycle Induction in Lymphoid Cells, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 74. |
Lo C.L.R., Chan S.C., Chan K.L., Chiang A.K.S., Lo C.M. and Ng I.O.L., Post-transplant lymphoproliferative disorders in liver transplant recipients: a clinicopathological study, Journal of Clinical Pathology. 2013, Epub on 2013-02-19: 392-8. |
Mann G., Rosolen A., Horibe K., Uyttebroeck A., Beishuizen A., Niggli F., Csoka M., Krenova Z., Melgren K., Kabickova E., Chiang A.K.S., Reiter A., Williams D., Burkhardt B. and Attarbaschi A., Clinical characteristics and outcome of pediatric and adolescent patients with follicular lymphoma - The EICNHL and i-BFM study groups experience, British Journal of Haematology - Fourth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin's Lymphoma, 1-3 Nov 2012, New York, USA. 2012. |
Ning J., Chan K.H. and Chiang A.K.S., Epstein-barr Virus (EBV) - specific CD4+ and CD8_ T Cell REsponses Shift from Targeting Lytic- to Latent-cycle Proteins with Concurrent Development of Increased Polyfunctionality from the Acute to Persistent Phase of EBV Infection, 17th Research Postgraduate Symposium, Dec 12-13, 2012. 216. |
Robles J.D., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Norovirus infection in pediatric hematopoietic stem cell transplant recipients: incidence, risk factors and outcome, Biology of Blood and Marrow Transplant. 2012, in press. |
Surapolchai P., Ha S.Y., Chan G.C.F., Lukito J.B., Wan T.S.K., So J.C.C. and Chiang A.K.S., Central Diabetes Insipidus: An Unusual Complication in a Child With Juvenile Myelomonocytic Leukemia and Monosomy 7, Journal of Pediatric Hematology and Oncology. 2013, 35: e84-e87. |
Xiong H., Ha S.Y., Chiang A.K.S., Hu Q. and Chan G.C.F., A small cohort review of the long-term prognosis for Chinese older children and adolescents with acute lymphoblastic leukaemia treated on a paediatric protocol, Hong Kong Journal of Paediatrics (new series). 2013, 18: 89-95. |
Yang J., Cheuk K.L.D., Ha S.Y., Chiang A.K.S., Lee T.L., Ho M.H.K. and Chan G.C.F., Infliximab for steroid refractory or dependent gastrointestinal acute graft-versus-host disease in children after allogeneic hematopoietic stem cell transplantation, Pediatr Transplant. 2012, 16(7): 771-8. |
Researcher : Chiu SSS |
Project Title: | Streptococcus pneumoniae carriage in young children in Hong Kong |
Investigator(s): | Chiu SSS, Ho PL |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Health Services Research Fund - Full Grants |
Start Date: | 10/1999 |
Project Title: | Impact of universal vaccination with the 7-valent conjugate pneumocccal vaccine (PCV7) in Hong Kong on the incidence of pneumonia hospitalization and carriage in children |
Investigator(s): | Chiu SSS, Ho PL |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Centre for Health Protection |
Start Date: | 07/2010 |
List of Research Outputs |
Chan K.H., To K.K.W., Chan B.W., Li C.P., Chiu S.S.S., Yuen K.Y. and Ho P.L., Comparison of Pyrosequencing, Sanger Sequencing, and Melting Curve Analysis for Detection of Low-Frequency Macrolide-Resistant Mycoplasma pneumoniae Quasispecies in Respiratory Specimens., Journal of Clinical Microbiology . 2013, 51: 2592-2598. |
Chiu S.S.S., Associate Editor, BMC Infectious Diseases . 2013. |
Chiu S.S.S., HIV infection in infants and children , HIV Manual . the Department of Health, 2013. |
Chu K.W., Poon L.L.M., Chiu S.S.S., Chan K.H., Ng E.M., Bauer I.R.M.A., Cheung T.I.M. .K., Ng I.H.Y., Guan Y., Wang D.A.V.I.D. and Peiris J.S.M., Characterization of a novel gyrovirus in human stool and chicken meat, Journal of Clinical Virology. 2012, 55(3): 209-13. |
Cowling B.J., Ng S., Ma E.S.K., Fang J., So H.C., Lim Wai W.S., Cheng K.Y., Wong Y.T., Chan K.H., Ip D.K.M., Chiu S.S.S., Peiris J.S.M. and Leung G.M., Protective efficacy against pandemic influenza of seasonal influenza vaccination in children in Hong Kong: A randomized controlled trial, Clinical Infectious Diseases. 2012, 55(5): 695-702. |
Klick B.A., Durrani S., Chan K.H., Ip D.K.M., Chou S.K., Kwok H.K.H., Ng S., Chiu S.S.S., Peiris J.S.M., Leung G.M. and Cowling B.J., Live attenuated seasonal and pandemic influenza vaccine in school-age children: A randomized controlled trial, Vaccine. 2013, 31(15): 1937-43. |
Ng S., Ip D.K.M., Fang J., Chan K.H., Chiu S.S.S., Leung G.M., Peiris J.S.M. and Cowling B.J., Efficacy and effectiveness of trivalent inactivated influenza vaccination against confirmed influenza, acute respiratory illness, and medically attended acute respiratory illness (abstract and poster presentation), Incidence, Severity, and Impact 2012: An isirv International Conference on Seasonal and Pandemic Influenza, 5-8 September 2012, Munich, Germany. Munich, Germany, ISIRV, 2012, 72. |
Ng S., Fang J., Ip D.K.M., Chiu S.S.S., Leung G.M., Peiris J.S.M. and Cowling B.J., Humoral antibody response after receipt of inactivated seasonal influenza vaccinations one year apart in children, Pediatric Infectious Disease Journal. 2012, 31(9): 964-9. |
Ng S., Ip D.K.M., Fang J., Chan K.H., Chiu S.S.S., Leung G.M., Peiris J.S.M. and Cowling B.J., The effect of age and recent influenza vaccination history on the immunogenicity and efficacy of 2009-10 seasonal trivalent inactivated influenza vaccination in children, PLoS One. 2013, 8(3): e59077. |
Ng S., Ip D.K.M., Fang J., Chan K.H., Chiu S.S.S., Peiris J.S.M., Leung G.M. and Cowling B.J., Trivalent inactivated influenza vaccine and medically attended acute respiratory illnesses in children and their households, a cluster randomized controlled trial (abstract and oral presentation), Hong Kong College of Community Medicine Annual Scientific Meeting, 15 September 2012, Hong Kong. Hong Kong, Hong Kong College of Community Medicine, 2012, Free paper 1. |
Yang L., Chan K.P., Cowling B.J., Chiu S.S.S., Chan K.H., Peiris J.S.M. and Wong C.M., Excess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong Kong, Epidemiology and Infection. 2012, 140(9): 1542-50. |
Researcher : Choi CK |
List of Research Outputs |
Choi C.K., Ho D.N.Y., Hui K.F., Kao R.Y.T. and Chiang A.K.S., High-thoughput Screening of Small Organic Molecules for Activation of Lytic Cycle of Epstein-Barr Virus (EBV) in EBV-positive Epithelial Malignancies, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 68. |
Researcher : Chong CY |
List of Research Outputs |
Li P.H., Wong W.H.S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Tong K.L., Tse N.K.C., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chong C.Y., Wong R.W.S., Mok T.M.Y., Ying S.K.Y., Fung S.K.S., Lai W.M., Yang W. and Lau Y.L., Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology. Oxford, 2013, 52(2): 337-345. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : Chong WP |
List of Research Outputs |
Chong W.P., Ling M.T., Liu Y., Tu W. and Lau Y.L., Essential Role of NK Cells in IgG Therapy for Experimental Autoimmune Encephalomyelitis, Plos One. 2013. |
Researcher : Chow CB |
Project Title: | Use of Internet marketing in promotion of smoking cessation among youths in Hong Kong |
Investigator(s): | Chow CB, Ip P, Lam TH, Chan SSC |
Department: | HKJC Ctr for Suicide Research & Preventn |
Source(s) of Funding: | Health and Health Services Research Fund - Full Grants |
Start Date: | 07/2012 |
List of Research Outputs |
Chow C.B., Ip P., Wong R.M.S. and Chan G.C.F., Submission to Panel on Health Services on the regulation of formula products and foods for infants and young children. Letter of recommendations to Hong Kong Legislative Council, LC Paper No. CB(2)213/12-13(03), Legislative Council, Hong Kong, 20 November 2012., 2012. |
Lee S.L., Tinsley H.M., Chau J., Lai H.K., Thach T.Q., Ip P., Chow C.B. and Hedley A.J., Review of Outdoor Air Pollution and Child Health in Hong Kong, Hong Kong Journal of Paediatrics (new series). 2013, 18(2): 69-76. |
Leung C., Johnston J.M., Chow C.B. and Lam T.H., In-depth exploration of unintentional childhood injuries in low-income settings in Hong Kong (abstract and poster presentation), 17th Research Postgraduate Symposium, 12-13 December 2012, Hong Kong. Hong Kong, LKS faculty of Medicine, HKU, 2012, 149. |
Rao N., Sun J., Ng S.S.N., Ma K., Becher Y., Lee D., Lau C., Zhang L., Chow C.B. and Ip P., The Hong Kong Early Child Development Scale: A Validation Study, Res. 2013 Mar;6(1):115-135. Epub 2012 Oct 3. 2012, DOI 10.1007/s12187-012-9161-7. |
Rao N., Sun J., Ng S.S.N., Ma K., Becher Y., LEE P.L.D., LAU G.L.C., ZHANG L.I., Chow C.B. and Ip P., The Hong Kong early child development scale: A validation study., Child Indicators Research. Springer, 2013, 6: 115-135. |
Researcher : Chow PC |
List of Research Outputs |
Chow P.C., Chan K.W., Lun K.S., Yung T.C., Cheung Y.F. and Chau A.K.T., Outcome of pregnancy in women with congential heart diseases (CHD) of a tertiary centre in Hong Kong, 21st Annual Scientific Scientific Congress, Hong Kong College of Cardiology, 8 June 2013. |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Researcher : Chu LYV |
List of Research Outputs |
Wong V.C.N., Cheuk K.L.D., Lee S. and Chu L.Y.V., Acupuncture for acute management and rehabilitation of traumatic brain injury, Cochrane Database of Systemic Review. John Wiley & Sons, Ltd., 2013, 3: 1-36. |
Wong V.C.N., Cheuk K.L.D. and Chu L.Y.V., Acupuncture for hypoxic ischemic encephalopathy in neonates, Cochrane Database of Systematic Reviews. 2013, 1: 1-22. |
Researcher : Chung BHY |
Project Title: | A Pilot Study on Genome-Wide DNA Methylation Profiling in Systemic Lupus Erythematosus (SLE) |
Investigator(s): | Chung BHY, Lau YL, Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Seed Funding Programme for Basic Research |
Start Date: | 05/2011 |
Completion Date: | 10/2012 |
Project Title: | Genome-wide DNA methylation profiling in Chinese patients with Systemic Lupus Erythematosus (SLE) |
Investigator(s): | Chung BHY, Lau YL, Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 09/2011 |
Project Title: | Provision of molecular diagnosis for patients with birth defects/genetic conditions in Hong Kong |
Investigator(s): | Chung BHY, Lau YL, Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
Start Date: | 02/2012 |
Project Title: | Identification of Epigenetic alterations in Imprinting Growth disorders |
Investigator(s): | Chung BHY, Chan KW, Wong KY, Li RHW, Tang MHY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 06/2012 |
Project Title: | Comprehensive genetic evaluation of children with autism spectrum disorders in Hong Kong |
Investigator(s): | Chung BHY, Wong VCN, Lee SL, Fung CW |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
Start Date: | 08/2012 |
Project Title: | 33rd Annual David W. Smith Workshop on Malformations and Morphogenesis Infantile systemic hyalinosis (ISH) – in-vitro study of the C218R mutant on the role of the ER degradation system as the target for individualized therapeutic intervention |
Investigator(s): | Chung BHY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 08/2012 |
Project Title: | Copy-number variations in Chinese patients with conotruncal defects - a pilot study of 100 patients |
Investigator(s): | Chung BHY, Liu APY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Children's Heart Foundation - General Award |
Start Date: | 03/2013 |
Project Title: | Identification of DNA methylation changes in Chinese patients with early-onset Systemic Lupus Erthematosus by bisulfite-converted DNA pyrosequencing |
Investigator(s): | Chung BHY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 05/2013 |
List of Research Outputs |
Aldinger K.A., Kogan J., Kimonis V., Fernandez B., Horn D., Klopocki E., Chung B.H.Y., Toutain A., Weksberg R., Millen K.J., Barkovich A.J. and Dobyns W.B., Cerebellar and Posterior Fossa Malformations in Patients With Autism-Associated Chromosome 22q13 Terminal Deletion, American Journal of Medical Genetics (Part A). 2012, 161A: 131-136. |
Chung B.H.Y., Luk H.M., Lo I.F.M., Lam S.T.S. and Li R.H.W., A second report of p.Pro986Leu variant in COL2A1 - phenotypic overlap with SEDC and other forms of type II collagenopathies, American Journal of Medical Genetics (Part A). 2013, 161A: 918-920. |
Chung B.H.Y., Chairperson of Clinical Genetics Symposium Series S3 - Dwarfism: from prenatal diagnosis to postnatal treatment, 25 May 2013. 2013. |
Chung B.H.Y., Clinical Genetics - Understanding the discipline from a dental perspective, St. John Ambulance, 24 April 2013. 2013. |
Chung B.H.Y., Congenital malformation & genetic counselling, Institute of Advanced Nursing Studies, Hospital Authority, 15 November 2012. 2012. |
Chung B.H.Y., Coordinator for the genetics subtheme of the SRT, Centre for Reproduction, Development and Growth, HKU, 2013. 2013. |
Chung B.H.Y., Tao Q.V. and Tso W.Y.W., Copy number variation and autism: New insights and clinical implications, Journal of the Formosan Medical Association. 2013, 1-9. |
Chung B.H.Y., Counseling ethics, Hong Kong Society of Cytogenetics, Educational Classes (II), 2012-2013, Class 7, 5 March 2013. 2013. |
Chung B.H.Y., Counseling ethics, Hong Kong Society of Cytogenetics, Educational Classes (II), 2012-2013, Class 8, 5 March 2013. 2013. |
Chung B.H.Y., Genetic Counselling, 10th Asia Pacific Conference on Human Genetics, Kuala Lumpur, Malaysia, 5-8 December 2012. |
Chung B.H.Y., Hinek A., Bradley T., Grossse-Wortmann L., Blaser S. and Chitayat D., Hand abnormalities in Loeys-Dietz syndrome: Expanding the clinical spectrum, 33rd David W. Smith Workshop on Malformations and Morphogenesis, USA, 8-12 August 2012. |
Chung B.H.Y., Hinek A., Bradley T., Grossse-Wortmann L., Blaser S. and Chitayat D., Hand abnormalities in Loeys-Dietz syndrome: Expanding the clinical spectrum, ASHG 2012 Annual Meeting, San Francisco, USA, 6-12 November 2012. |
Chung B.H.Y., Identification of 22q11.2 deletion in patients from adult congenital heart disease clinic - A missed and found burden in the transition care, 9th Congress of the Asia Society for Paediatric Research ASPR and the 20th Annual Congress of the Perinatal Society of Malaysia (PSM, Malyasia, 9-12 May 2013. |
Chung B.H.Y., Identification of 22q11.2 deletion in patients from adult congenital heart disease clinic - a missed burden in the transition care, European Human Genetics Conference 2013 (ESHG), Paris, France, 8-11 June 2013. |
Chung B.H.Y. and Lausch E., Infantile Systemic Hyalinosis (ISH) - In Vitro Study of the C218R Mutant on the Role of the ER Degradation System as the Target for Individualized Therapeutic Intervention, 33rd David W. Smith Workshop on Malformations and Morphogenesis, USA, 8-12 August 2012. |
Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, 9th Congress of the Asia Society for Paediatric Research ASPR and the 20th Annual Congress of the Perinatal Society of Malaysia (PSM, Malyasia, 9-12 May 2013. |
Chung B.H.Y., Patients with common genetic syndromes - transition into adulthood, 2013 Pediatric Consultant Program, Macau, 28 June 2013. |
Chung B.H.Y., Reviewer of British Medical Journal . 2013. |
Chung B.H.Y., Reviewer of Hong Kong Journal of Paediatrics . 2013. |
Chung B.H.Y., Reviewer of Hong Kong Medical Journal . 2013. |
Chung B.H.Y., Reviewer of The Journal of Genetic Counselling . 2013. |
Chung B.H.Y., Reviewer, Reviewer of PLOS ONE. 2013. |
Chung B.H.Y., Role model of professionalism, Department of Family Medicine and Primary Care and Institute for Medical and Health Sciences Education, 7 May 2013. 2013. |
Chung B.H.Y., Two cases of vascular emergency highlighting the importance of TGF-beta signaling pathway, 13th AGM & Clinical Genetics Showcase Series - 1st Episode, 21 November 2012. |
Chung B.H.Y., Whole genome DNA methylation profiling in Chinese patients with SLE - The central rold of type I interferon pathway in the pathogenesis, 9th Congress of the Asia Society for Paediatric Research ASPR and the 20th Annual Congress of the Perinatal Society of Malaysia (PSM, Malyasia, 9-12 May 2013. |
Grafodatskaya D., Chung B.H.Y., Butcher D.J., Turinsky A.L., Goodman S.J., Choufani S., Chen Y.A., Lou Y., Zhao C., Rajendram R., Abidi F.E., Skinner C., Stavropoulos J., Bondy C.A., Hamilton J., Wodak S., Scherer S.W., Schwartz C.E. and Weksberg R., Multilocus loss of DNA methylation in individuals with mutations in the histone H3 Lysine 4 Demethylase KDM5C, BMC Medical Genomics. 2013, 6: 1-18. |
Ho C.C.A., Liu A.P.Y., Lun K.S., Tang W.F., Chan Y.K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aortic stenosis, microcephaly and dysmorphic facial features - Is cardiac assessment necessary for all patients with 17p13.3 microduplication?, European Journal of Medical Genetics. 2012, 55: 758-762. |
Ho C.C.A., Liu A.P.Y., Lun K.S. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aotic stenosis, microcephaly and dysmorphic facial features - is caridac assessment necessary for all patients with 17p13.3 microdup, [Case Report] London Dysmorphology & Neurogenetics Databases. 2012. |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Leung W.Y., Ip J.K.J. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2012, 17: 258-259. |
Leung W.Y., Liu A.P.Y. and Chung B.H.Y., [Clinical Quiz] What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2012, 17(3): 190. |
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318. |
Man E., Lafferty K.A., Funke B.H., Lun K.S., Chan S.Y., Chau A.K.T. and Chung B.H.Y., NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy, BMJ Case Reports [doi:10.1136/bcr-2012-007529]. 2013. |
Tang M.H.Y., Lau E.T.K., Tan T.Y., Chung B.H.Y. and Shek N.W.M., Prenatal Diagnosis of Agenesis of the Corpus Callosum and Cerebellar Vermian Hypoplasia Associated with a Microdeletion on Chromosome 1p32: Decision Minor revision, Case Reports in Perinatal Medicine. 2013, 2;1-2: 39-45. |
Tsang J.S., Tong D.K.H., Chung B.H.Y., Tang M.H.Y., Lau E.T.K., Chan G.C.F. and Law S.Y.K., Alport's syndrome: case of a giant esophageal tumor [Doi:10.1007/s10388-012-0355-3], Esophagus. Springer, 2013, 10: 114-117. |
Weksberg R., Jin H., Chen Y., Grafodatskaya D., Inbar-Feigenberg M., Chung B.H.Y., Cytrynbaum C. and Choufani S., NSD1 mutations in Sotos syndrome alter the DNA methylation landscape of genes involved in somatic growth and neuronal transmission, ASHG 2012 Annual Meeting, San Francisco, USA, 6-12 November 2012. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : Fung CW |
List of Research Outputs |
Kwong K.Y., Fung C.W., Chan S.Y. and Wong V.C.N., Identification of SCN1A and PCDH19 Mutations in Chinese Children with Dravet Syndrome, PLoSOne. 2012, 7(7): e41802. |
Tsang J.P.K., Poon W.L., Luk H.M., Fung C.W., Ching C.K., Mak C.M., Lam C.W., Siu T.S., Tam S. and Wong V.C.N., Arginase deficiency with new phenotype and a novel mutation: Contemporary Summary, Pediatric Neurology. 2012, 47(4): 263-269. |
Wong V.C.N., Kwong K.Y. and Fung C.W., Dravet Syndeome - Genetic Analysis of SCN1A and PCDH19 Mutations for 17 Chinese Children, 25th Annual Scientific Meeting of The Hong Kong Neurological Society. 3rd November 2012. |
Researcher : Ha SY |
List of Research Outputs |
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Health-Related Quality of Life in Children who Survive after Cancer Therapy, 19th Hong Kong International Cancer Congress, Nov 8-9, 2012, Hong Kong. 2012. |
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Malignancies in Chinese patients with neurofibromatosis type 1, Hong Kong Medical Journal. 2013, 19: 42-49. |
Cheung Y.F., Yu W., Li S.N., Lam W.W.M., Ho Y.C., Wong S.J., Chan G.C.F. and Ha S.Y., Dynamic dyssynchrony and impaired contractile reserve of the left ventricle in beta-thalassaemia major: an exercise echocardiographic study , PLOS One . 2012, 7: e45265. |
Robles J.D., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Norovirus infection in pediatric hematopoietic stem cell transplant recipients: incidence, risk factors and outcome, Biology of Blood and Marrow Transplant. 2012, in press. |
Surapolchai P., Ha S.Y., Chan G.C.F., Lukito J.B., Wan T.S.K., So J.C.C. and Chiang A.K.S., Central Diabetes Insipidus: An Unusual Complication in a Child With Juvenile Myelomonocytic Leukemia and Monosomy 7, Journal of Pediatric Hematology and Oncology. 2013, 35: e84-e87. |
Xiong H., Ha S.Y., Chiang A.K.S., Hu Q. and Chan G.C.F., A small cohort review of the long-term prognosis for Chinese older children and adolescents with acute lymphoblastic leukaemia treated on a paediatric protocol, Hong Kong Journal of Paediatrics (new series). 2013, 18: 89-95. |
Yang J., Cheuk K.L.D., Ha S.Y., Chiang A.K.S., Lee T.L., Ho M.H.K. and Chan G.C.F., Infliximab for steroid refractory or dependent gastrointestinal acute graft-versus-host disease in children after allogeneic hematopoietic stem cell transplantation, Pediatr Transplant. 2012, 16(7): 771-8. |
Yu W., Li S., Chan G.C.F., Ha S.Y., Wong S.J. and Cheung Y.F., Transmural strain and rotation gradient in survivors of childhood cancers, European Heart Journal Cardiovascular Imaging . 2012, 14: 175-182. |
Researcher : Ho CCA |
List of Research Outputs |
Ho C.C.A., Liu A.P.Y., Lun K.S., Tang W.F., Chan Y.K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aortic stenosis, microcephaly and dysmorphic facial features - Is cardiac assessment necessary for all patients with 17p13.3 microduplication?, European Journal of Medical Genetics. 2012, 55: 758-762. |
Ho C.C.A., Liu A.P.Y., Lun K.S. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aotic stenosis, microcephaly and dysmorphic facial features - is caridac assessment necessary for all patients with 17p13.3 microdup, [Case Report] London Dysmorphology & Neurogenetics Databases. 2012. |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Researcher : Ho DNY |
List of Research Outputs |
Choi C.K., Ho D.N.Y., Hui K.F., Kao R.Y.T. and Chiang A.K.S., High-thoughput Screening of Small Organic Molecules for Activation of Lytic Cycle of Epstein-Barr Virus (EBV) in EBV-positive Epithelial Malignancies, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 68. |
Ho D.N.Y., Hui K.F., Kao R.Y.T. and Chiang A.K.S., High-thoughput Screening of Small Organic Molecules for Activation of Lytic Cycle of Epstein-Barr Virus (EBV) in EBV-positive Epithelial Maglignancies, 17th Research Postgraduate Symposium, Dec 12 & 13, 2012. 2012. |
Hui K.F., Lam B.H.W., Ho D.N.Y. and Chiang A.K.S., Bortezomib and SAHA Synergistically Induce ROS-driven Casepase-dependent Apoptosis of Nasopharyngeal Carcinoma and Block Replication of Epstein-Barr Virus, 19th Hong Kong International Cancer Congress, Nov 8-9, 2012 Hong Kong . 2012. |
Hui K.F., Lam B.H.W., Ho D.N.Y., Tsao G.S.W. and Chiang A.K.S., Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus, Mol Cancer Ther. 2013, 12: 747-58. |
Hui K.F., Lam B.H.W., Ho D.N.Y. and Chiang A.K.S., Bortezomib combines with suberoylanilide hydroxamic acid (SAHA) to synergistically induce caspase-dependent apoptosis and blocks SAHA's activation of EBV lytic cycle in nasopharyngeal carcinoma, International Congress on Oncogenic Herpesviruses and Associated Diseases, Philadelphia, USA, Aug 1-4, 2012. |
Researcher : Ho MHK |
List of Research Outputs |
Ho M.H.K., Wong W.H.S. and Chang C., Clinical Spectrum of Food Allergies: a Comprehensive Review, Clinical Reviews in Allergy & Immunology. Springer, 2012, 41(3). |
Ho M.H.K., 食水含氯氟 恐易致食物敏感, Hong Kong Economic Times,5 December 2012. 2012. |
Ho M.H.K., 食物敏感 當心招哮喘, Ming Pao Daily News. 2013, 1. |
Ho M.H.K., 兒童食物過敏可致休克, Oriental Daily News, 23 June 2013. 2013. |
Ho M.H.K., Lee S.L., Wong W.H.S., Ip P. and Lau Y.L., Prevalence of self-reported food allergy in Hong Kong children and teens - a population survey, Asian Pacific Journal of Allergy Immunology. 2012, 30(4): 275-284. |
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L. and Lau Y.L., Autosomal Dominant Gain-of-function STAT1 Mutation is a Novel Genetic Etiology of Penicillium Marneffei Infection , Asian Society for Pediatric Research 2013. |
Lee P.P.W., He J.X., Chan K.W., Yang W., Jiang L.P., Liew W.K., Chen T.X., Ho M.H.K., Lee T.L. and Lau Y.L., Unique Pattern of Infections in Chronic Granulomatous Disease – The Asian Experience, Asian Society for Pediatric Research 2013. |
Li P.H., Wong W.H.S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Tong K.L., Tse N.K.C., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chong C.Y., Wong R.W.S., Mok T.M.Y., Ying S.K.Y., Fung S.K.S., Lai W.M., Yang W. and Lau Y.L., Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology. Oxford, 2013, 52(2): 337-345. |
Yang J., Cheuk K.L.D., Ha S.Y., Chiang A.K.S., Lee T.L., Ho M.H.K. and Chan G.C.F., Infliximab for steroid refractory or dependent gastrointestinal acute graft-versus-host disease in children after allogeneic hematopoietic stem cell transplantation, Pediatr Transplant. 2012, 16(7): 771-8. |
Yang L.H., Or C.T., Ho M.H.K. and Lau A.S.Y., Scientific basis of botanical medicine as alternative remedies for rheumatoid arthritis, Clinical Reviews in Allergy & Immunology. 2012, 2012: 1-17. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : Hui KF |
Project Title: | International Congress on Oncogenic Herpesviruses and Associated Diseases; Bortezomib combines with suberoylanilide hydroxamic acid (SAHA) to synergistically induce caspase-dependent apoptosis and blocks SAHA's activation of EBV lytic cycle in nasopharyngeal carcinoma |
Investigator(s): | Hui KF |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 08/2012 |
Project Title: | Investigation of histone modification on induction of Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma |
Investigator(s): | Hui KF, Chiang AKS |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 02/2013 |
List of Research Outputs |
Choi C.K., Ho D.N.Y., Hui K.F., Kao R.Y.T. and Chiang A.K.S., High-thoughput Screening of Small Organic Molecules for Activation of Lytic Cycle of Epstein-Barr Virus (EBV) in EBV-positive Epithelial Malignancies, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 68. |
Ho D.N.Y., Hui K.F., Kao R.Y.T. and Chiang A.K.S., High-thoughput Screening of Small Organic Molecules for Activation of Lytic Cycle of Epstein-Barr Virus (EBV) in EBV-positive Epithelial Maglignancies, 17th Research Postgraduate Symposium, Dec 12 & 13, 2012. 2012. |
Hui K.F., Lam B.H.W., Ho D.N.Y. and Chiang A.K.S., Bortezomib and SAHA Synergistically Induce ROS-driven Casepase-dependent Apoptosis of Nasopharyngeal Carcinoma and Block Replication of Epstein-Barr Virus, 19th Hong Kong International Cancer Congress, Nov 8-9, 2012 Hong Kong . 2012. |
Hui K.F., Lam B.H.W., Ho D.N.Y., Tsao G.S.W. and Chiang A.K.S., Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus, Mol Cancer Ther. 2013, 12: 747-58. |
Hui K.F., Lam B.H., Ho D.N., Tsao G.S.W. and Chiang A.K.S., Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus, Molecular Cancer Therapeutics. 2013, 12(5). |
Hui K.F., Lam B.H.W., Ho D.N.Y. and Chiang A.K.S., Bortezomib combines with suberoylanilide hydroxamic acid (SAHA) to synergistically induce caspase-dependent apoptosis and blocks SAHA's activation of EBV lytic cycle in nasopharyngeal carcinoma, International Congress on Oncogenic Herpesviruses and Associated Diseases, Philadelphia, USA, Aug 1-4, 2012. |
Leon Y.Y., Hui K.F. and Chiang A.K.S., The Combinatorial Effects of Histone Methyltrasferase Inhibitors with Histone Deacetylase Inhibitors on Epstein-Barr Virus Lytic Cycle Induction in Lymphoid Cells, 17th Research Pstograduate Symposium, Dec 12-13, 2012. 2012. |
Leung Y.Y., Hui K.F. and Chiang A.K.S., The Combinatorial Effects of Histone Methyltrasferase Inhibitors with Histone Deacetylase Inhibitors on Epstein-Barr Virus Lytic Cycle Induction in Lymphoid Cells, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 74. |
Researcher : Ip P |
Project Title: | Early Detoxification of Substance Abusing Mothers improves developmental and behavioural outcome of their children |
Investigator(s): | Ip P, Chan EKL |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Seed Funding Programme for Basic Research |
Start Date: | 06/2010 |
Completion Date: | 12/2012 |
Project Title: | The Early Development of Children from different Socioeconomic Backgrounds. Do Our Children need early intervention? |
Investigator(s): | Ip P, Bacon-Shone J, Lau YL, Rao N |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 07/2011 |
List of Research Outputs |
Bray M., Chen E., Ip P., Lee D., Rao N., Shaeffer S., Sun J., Weekes B., Wong J. and Young M., Early Childhood Development and Cognitive Development in Developing Countries: A Rigorous Literature Review , Report submitted to Department for International Development, United Kingdom 2013 . 2013. |
Chan E.K.L., Yan E.C.W., Brownridge D.A. and Ip P., Associating Child Sexual Abuse with Child Victimization in China, The Journal of Pediatrics, 2013, v. 162 n. 5, p. 1028-1034. 2013, 162(5): 1028-1034. |
Chow C.B., Ip P., Wong R.M.S. and Chan G.C.F., Submission to Panel on Health Services on the regulation of formula products and foods for infants and young children. Letter of recommendations to Hong Kong Legislative Council, LC Paper No. CB(2)213/12-13(03), Legislative Council, Hong Kong, 20 November 2012., 2012. |
Ho M.H.K., Lee S.L., Wong W.H.S., Ip P. and Lau Y.L., Prevalence of self-reported food allergy in Hong Kong children and teens - a population survey, Asian Pacific Journal of Allergy Immunology. 2012, 30(4): 275-284. |
Ip P., "Child Abuse in Hong Kong and the importance of building an effective surveillance system in Chinese societies" published in "Child Protection in Chinese Societies: Policies and Challenges" 2012; Publisher: Nova Science Publishers, 2012. |
Ip P., Attention Deficit-Hyperactivity Disorder , HKU KGKF Health & Health Services Research Initiatives for Families Health Literacy Programme, Hong Kong 4 Aug 2012 . 2012. |
Ip P., Wong W.H.S. and Li L., Child Abuse in Hong Kong and the Importance of Building an Effective Surveillance System in Chinese Societies, Nova Science Publishers, Inc. New York, 2013, 265-280. |
Ip P., Hong Kong Journal of Paediatrics - Blood lead and cadmium levels of children: A case study in Changchun, Jilin Province, China, August 2012 , 2012. |
Ip P., Physical activity rates among adolescents: The gender role in spain. Hong Kong Journal of Paediatrics, December 2012. , 2012. |
Ip P., Physical and Mental Development , HKU KGKF Health & Health Services Research Initiatives for Families Health Literacy Programme, Hong Kong 4 Aug 2012. 2012. |
Ip P., 童心放晴」成長計劃-走出情緒困擾/抑鬱的世界研討會 - 防止虐待兒童會 (22 Mar 2013) , 2013. |
Ip P., 過度活躍 男女比例 4:1 (Oriental Daily News) 2012年12月16日.. 2012. |
Lee S.L., Tinsley H.M., Chau J., Lai H.K., Thach T.Q., Ip P., Chow C.B. and Hedley A.J., Review of Outdoor Air Pollution and Child Health in Hong Kong, Hong Kong Journal of Paediatrics (new series). 2013, 18(2): 69-76. |
Rao N., Sun J., Ng S.S.N., Ma K., Becher Y., Lee D., Lau C., Zhang L., Chow C.B. and Ip P., The Hong Kong Early Child Development Scale: A Validation Study, Res. 2013 Mar;6(1):115-135. Epub 2012 Oct 3. 2012, DOI 10.1007/s12187-012-9161-7. |
Rao N., Sun J., Ng S.S.N., Ma K., Becher Y., LEE P.L.D., LAU G.L.C., ZHANG L.I., Chow C.B. and Ip P., The Hong Kong early child development scale: A validation study., Child Indicators Research. Springer, 2013, 6: 115-135. |
Researcher : Jalal K |
List of Research Outputs |
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318. |
Researcher : Kwok H |
List of Research Outputs |
Kwok H., Tong A.H.Y., Lin C., Lok S., Farrell P.J., Kwong D.L.W. and Chiang A.K.S., Genomic Sequencing and Comparative Analysis of Epstein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma Biopsy, 17th Research Postgradute Symposium, Dec 12 & 13, 2012. 2012. |
Kwok H., Tong A.H.Y., Lin C., Lok S., Ferrell P.J., Kwong D.L.W. and Chiang A.K.S., Genomic Sequencing and Comparative Analysis of Epstein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma Biopsy, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 167. |
Kwok H., Tong A.H.Y., Lin C., Lok S., Farrell P.J., Kwong D.L.W. and Chiang A.K.S., Genomic Sequencing and Comparative Analysis of Esptein-Barr Virus Genome Isolated from Primary Nasopharyngeal Carcinoma Biopsy, 19th Hong Kong International Cancer Congress - 8-9 Nov 2012, Hong Kong. 2012. |
Researcher : Kwong KY |
List of Research Outputs |
Kwong K.Y., Fung C.W., Chan S.Y. and Wong V.C.N., Identification of SCN1A and PCDH19 Mutations in Chinese Children with Dravet Syndrome, PLoSOne. 2012, 7(7): e41802. |
Wong V.C.N., Kwong K.Y. and Fung C.W., Dravet Syndeome - Genetic Analysis of SCN1A and PCDH19 Mutations for 17 Chinese Children, 25th Annual Scientific Meeting of The Hong Kong Neurological Society. 3rd November 2012. |
Researcher : LING WL |
List of Research Outputs |
LING W.L., WANG L., PONG C.H., Lau A.S.Y. and Li C.B., A role of IL-17A in modulating intracellular survival of Mycobacterium bovis BCG in murine macrophages, Immunology. 2013. |
Researcher : Lau ASY |
Project Title: | Cytokines, Signaling & Diseases 2003 The Role of Protein Kinase PKR in the Induction of Cytokine Expression by Bacillus Calmette Guerin Through NF-kappaB |
Investigator(s): | Lau ASY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 10/2003 |
Project Title: | Cytokine Dysregulation and Virus-Induced Cell Death in Avian Influenza Virus Infections |
Investigator(s): | Lau ASY, Peiris JSM |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 11/2005 |
Project Title: | Factors affecting mycobacteria evasion of immunity: effects of HIV on cellular signaling and kinases |
Investigator(s): | Lau ASY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
Start Date: | 09/2009 |
Project Title: | Mycobacteria Evasion of Immunity: a Potential Role for IL-10 and its consequent Suppression of MHC Antigen Expression |
Investigator(s): | Lau ASY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 10/2009 |
Completion Date: | 09/2012 |
List of Research Outputs |
LING W.L., WANG L., PONG C.H., Lau A.S.Y. and Li C.B., A role of IL-17A in modulating intracellular survival of Mycobacterium bovis BCG in murine macrophages, Immunology. 2013. |
Law H.Y., Tam A.H., Lee D.C.W. and Lau A.S.Y., A role for protein phosphatase 2A in regulating p38 mitogen activated protein kinase activation and tumor necrosis factor-alpha expression during influenza virus infection., International Journal of Molecular Sciences (in press). 2012. |
Law H.Y., Yang L.H. and Lau A.S.Y., Mechanism of action and molecular identification of individual bio-active constituents from an effective traditional Chinese medicine decoction in treating influenza virus infection., Science Translational Medicine (in press). 2012. |
Li H., Seneviratne C.J., Lau A.S.Y., Wang C.Y. and Jin L., Commensals and periodontopathogens modulate immuno-inflammatory trajectories in HOKs and THP-1, Journal of Dental Research. 2012, 91 (Spec Iss C): 169577 (SEA Division). |
Li H., Seneviratne C.J., Lau A.S.Y., Wang C.Y. and Jin L., Commensals and periodontopathogens modulate immuno-inflammatory trajectories in HOKs and THP-1, Journal of Dental Research. 2013, 92 (Spec Iss A): 2285. |
Pong C.H., Li C.B., Yim H.C.H. and Lau A.S.Y., THE ROLE OF C-MYC IN REGULATING HIV-1 TAT PROTEIN INDUCED CYTOKINE EXPRESSION AND CONSEQUENT EFFECTS ON OPPORTUNISTIC INFECTION, 10th Joint Annual Meeting of the International Cytokine Society (ICS) and the International Society for Interferon and Cytokine Research (ISICR). 2012. |
QI H., ZHAO J., Han Y.F., Lau A.S.Y. and Rong J., Z-Ligustilide Potentiates the Cytotoxicity of Dopamine in Rat Dopaminergic PC12 Cells, 11th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Macau, August 21 - 23, 2012 . 2012. |
Yang L.H., Or C.T., Ho M.H.K. and Lau A.S.Y., Scientific basis of botanical medicine as alternative remedies for rheumatoid arthritis, Clinical Reviews in Allergy & Immunology. 2012, 2012: 1-17. |
Researcher : Lau YL |
Project Title: | A community-based educational program on thalassaemias to enhance awareness with the aim to reduce burden of thalassaemia related health problems in Hong Kong |
Investigator(s): | Lau YL, Ha SY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Health Promotion Projects |
Start Date: | 09/1997 |
Project Title: | Comparison of process upgrade varicella vaccine (Puvv) with VARILRIX-TM |
Investigator(s): | Lau YL |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Other Funding Scheme |
Start Date: | 07/1999 |
Project Title: | Association of cytokine and chemokine genes polymorphism with susceptibility to SARS and severity of SARS |
Investigator(s): | Lau YL, Peiris JSM |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
Start Date: | 09/2005 |
Project Title: | p21 gene polymorphism with systemic lupus erythematosus and rheumatoid arthritis |
Investigator(s): | Lau YL, Lau WCS |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 09/2005 |
Project Title: | Association of STAT4, ITGAM, BLK and PXK gene polymorphisms with systemic lupus erythematosus (SLE) |
Investigator(s): | Lau YL, Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 09/2008 |
Project Title: | Identification of coding variants associated with early-onset and familial systemic lupus erythematosus through whole exome sequencing and replication |
Investigator(s): | Lau YL, Sham PC, Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 11/2011 |
List of Research Outputs |
Chong W.P., Ling M.T., Liu Y., Tu W. and Lau Y.L., Essential Role of NK Cells in IgG Therapy for Experimental Autoimmune Encephalomyelitis, Plos One. 2013. |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Ho M.H.K., Lee S.L., Wong W.H.S., Ip P. and Lau Y.L., Prevalence of self-reported food allergy in Hong Kong children and teens - a population survey, Asian Pacific Journal of Allergy Immunology. 2012, 30(4): 275-284. |
Kaiser R., Kaiser R., Taylor K.E., Deng Y., Zhao J., Li Y., Nititham J., Chang M., Catanese J., Begovich A.B., Brown E.E., Edberg J.C., McGwin G., Alarcon G.S., Ramsey-Goldman R., Reveille J.D., Vila L.M., Petri M., Kimberly R.P., Feng X., Sun L., Shen N., Li W., Lu J.X., Wakeland E.K., Li Q.Z., Yang W., Lau Y.L., Liu F.L., Chang D.M., Yu C.Y., Song Y.W., Tsao B.P. and Criswell L.A., Single-Nucleotide Polymorphisms in VKORC1 Are Risk Factors for Systemic Lupus Erythematosus in Asians, Arthritis & Rheumatism. 2013, 65(1): 211-215. |
Lau S.K.P., Yip C.Y., Lung D.C., Lee P., Que T.L., Lau Y.L., Chan K.H., Woo P.C.Y. and Yuen K.Y., Detection of human rhinovirus C in fecal samples of children with gastroenteritis, Journal of Clinical Virology. 2012, 53: 290-296. |
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L. and Lau Y.L., Autosomal Dominant Gain-of-function STAT1 Mutation is a Novel Genetic Etiology of Penicillium Marneffei Infection , Asian Society for Pediatric Research 2013. |
Lee P.P.W., He J.X., Chan K.W., Yang W., Jiang L.P., Liew W.K., Chen T.X., Ho M.H.K., Lee T.L. and Lau Y.L., Unique Pattern of Infections in Chronic Granulomatous Disease – The Asian Experience, Asian Society for Pediatric Research 2013. |
Lee S.L., Cheung Y.F., Wong W.H.S., Leung T.H., Lam T.H. and Lau Y.L., Chronic health problems and health-related quality of life in Chinese children and adolescents: a population-based study in Hong Kong., British Medical Journal Open . 2013, 3: e001183.doi:10.1136/bmjopen-2012-001183. |
Lee S.L., Lam T.H., Leung T.H., Wong W.H.S., Schooling M., Leung G.M. and Lau Y.L., Foetal Exposure to Maternal Passive Smoking Is Associated with Childhood Asthma, Allergic Rhinitis, and Eczema, Scientific World Journal. 2012, 2012: 1-9. |
Li P.H., Wong W.H.S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Tong K.L., Tse N.K.C., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chong C.Y., Wong R.W.S., Mok T.M.Y., Ying S.K.Y., Fung S.K.S., Lai W.M., Yang W. and Lau Y.L., Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology. Oxford, 2013, 52(2): 337-345. |
Wong E.H.M., Cui L., Ng C.L., Tang S.M., Liu X., So M.T., Yip B.H.K., Cheng G., Zhang R., Tang W.K., Yang W., Lau Y.L., Baum L., Kwan P., Sun L.D., Zuo Z.B., Ren Y.Q., Yin X.Y., Miao X., Liu J.J., Lui V.C.H., Ngan E.S.W., Yuan Z.W., Zhang S.W., Xia J.L., Wang H.L., Sun X.B., Wang R.Y., Chang T., Chan I.H.Y., Chung H.Y., Zhang X.J., Wong K.K.Y., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number variation study in anorectal malformations, Human Molecular Genetics. 2013, 22(3): 621-631. |
Yang J., Yang W. and Lau Y.L., Gene-gene Interaction In Disease Association For Systemic Lupus Erythematosus In Asian Populations. , American Society Of Human Genetics, 2012. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Zhang L., Zhang J., Yang J., Ying D., Lau Y.L. and Yang W., PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data, Bioinformatics. 2013, 29(1): 124-125. |
Zheng J., Liu Y., Lau Y.L. and Tu W., Human CD8 regulatory T cells inhibit graft-versus-host disease and preserve general immunity in humanized mice, Science Translational Medicine. 2013. |
Zheng J., Liu Y., liu M., Lau Y.L. and Tu W., Human CD8 regulatory T cells inhibit graft-versus-host disease and preserve general immunity in humanized mice, Science Translational Medicine . 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., unpolished sword in human antiviral Immunity, Cellular and Molecular Immunology. 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., γδ-T cells: an unpolished sword in human anti-infection immunity, Cellular and Molecular Immunology. 2013, 10: 50-57. |
Researcher : Law HY |
List of Research Outputs |
Law H.Y., Tam A.H., Lee D.C.W. and Lau A.S.Y., A role for protein phosphatase 2A in regulating p38 mitogen activated protein kinase activation and tumor necrosis factor-alpha expression during influenza virus infection., International Journal of Molecular Sciences (in press). 2012. |
Law H.Y., Yang L.H. and Lau A.S.Y., Mechanism of action and molecular identification of individual bio-active constituents from an effective traditional Chinese medicine decoction in treating influenza virus infection., Science Translational Medicine (in press). 2012. |
Researcher : Lee DCW |
List of Research Outputs |
Law H.Y., Tam A.H., Lee D.C.W. and Lau A.S.Y., A role for protein phosphatase 2A in regulating p38 mitogen activated protein kinase activation and tumor necrosis factor-alpha expression during influenza virus infection., International Journal of Molecular Sciences (in press). 2012. |
Researcher : Lee PPW |
Project Title: | Asian Society for Pediatric Research (ASPR) & Perinatal Society of Malaysia (PSM) 2013 Joint Meeting; Autosomal Dominant Gain-of-function STAT1 Mutation is a Novel Genetic Etiology of Penicillium Marneffei Infection /Unique pattern of infections in chronic granulomatous disease - The Asian experience |
Investigator(s): | Lee PPW |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 05/2013 |
List of Research Outputs |
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L. and Lau Y.L., Autosomal Dominant Gain-of-function STAT1 Mutation is a Novel Genetic Etiology of Penicillium Marneffei Infection , Asian Society for Pediatric Research 2013. |
Lee P.P.W., He J.X., Chan K.W., Yang W., Jiang L.P., Liew W.K., Chen T.X., Ho M.H.K., Lee T.L. and Lau Y.L., Unique Pattern of Infections in Chronic Granulomatous Disease – The Asian Experience, Asian Society for Pediatric Research 2013. |
Li P.H., Wong W.H.S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Tong K.L., Tse N.K.C., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chong C.Y., Wong R.W.S., Mok T.M.Y., Ying S.K.Y., Fung S.K.S., Lai W.M., Yang W. and Lau Y.L., Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology. Oxford, 2013, 52(2): 337-345. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : Lee SL |
List of Research Outputs |
Chau C.S.K. and Lee S.L., Successful use of BiPAP in infants with congenital myotonic dystrophy, Pediatrics International. 2013, 55(2): 243-245. |
Ho M.H.K., Lee S.L., Wong W.H.S., Ip P. and Lau Y.L., Prevalence of self-reported food allergy in Hong Kong children and teens - a population survey, Asian Pacific Journal of Allergy Immunology. 2012, 30(4): 275-284. |
Lee S.L., Cheung Y.F., Wong W.H.S., Leung T.H., Lam T.H. and Lau Y.L., Chronic health problems and health-related quality of life in Chinese children and adolescents: a population-based study in Hong Kong., British Medical Journal Open . 2013, 3: e001183.doi:10.1136/bmjopen-2012-001183. |
Lee S.L., Lam T.H., Leung T.H., Wong W.H.S., Schooling M., Leung G.M. and Lau Y.L., Foetal Exposure to Maternal Passive Smoking Is Associated with Childhood Asthma, Allergic Rhinitis, and Eczema, Scientific World Journal. 2012, 2012: 1-9. |
Lee S.L., Tinsley H.M., Chau J., Lai H.K., Thach T.Q., Ip P., Chow C.B. and Hedley A.J., Review of Outdoor Air Pollution and Child Health in Hong Kong, Hong Kong Journal of Paediatrics (new series). 2013, 18(2): 69-76. |
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318. |
Mak K.K., Lee S.L., Ho D.S.Y., Lo W.S. and Lam T.H., Sleep and academic performance in Hong Kong adolescents, Journal of School Health. 2012, 82(11): 522-7. |
Researcher : Lee TL |
List of Research Outputs |
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L. and Lau Y.L., Autosomal Dominant Gain-of-function STAT1 Mutation is a Novel Genetic Etiology of Penicillium Marneffei Infection , Asian Society for Pediatric Research 2013. |
Lee P.P.W., He J.X., Chan K.W., Yang W., Jiang L.P., Liew W.K., Chen T.X., Ho M.H.K., Lee T.L. and Lau Y.L., Unique Pattern of Infections in Chronic Granulomatous Disease – The Asian Experience, Asian Society for Pediatric Research 2013. |
Li P.H., Wong W.H.S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Tong K.L., Tse N.K.C., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chong C.Y., Wong R.W.S., Mok T.M.Y., Ying S.K.Y., Fung S.K.S., Lai W.M., Yang W. and Lau Y.L., Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology. Oxford, 2013, 52(2): 337-345. |
Yang J., Cheuk K.L.D., Ha S.Y., Chiang A.K.S., Lee T.L., Ho M.H.K. and Chan G.C.F., Infliximab for steroid refractory or dependent gastrointestinal acute graft-versus-host disease in children after allogeneic hematopoietic stem cell transplantation, Pediatr Transplant. 2012, 16(7): 771-8. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : Leon YY |
List of Research Outputs |
Leon Y.Y., Hui K.F. and Chiang A.K.S., The Combinatorial Effects of Histone Methyltrasferase Inhibitors with Histone Deacetylase Inhibitors on Epstein-Barr Virus Lytic Cycle Induction in Lymphoid Cells, 17th Research Pstograduate Symposium, Dec 12-13, 2012. 2012. |
Researcher : Leung YY |
List of Research Outputs |
Leung Y.Y., Hui K.F. and Chiang A.K.S., The Combinatorial Effects of Histone Methyltrasferase Inhibitors with Histone Deacetylase Inhibitors on Epstein-Barr Virus Lytic Cycle Induction in Lymphoid Cells, 17th Research Postgrduate Symposium, Dec 12-13, 2012. 74. |
Researcher : Li CB |
Project Title: | A role for oncogenes in the regulation of immune response to Mycobacterial infection |
Investigator(s): | Li CB |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 10/2010 |
Project Title: | Anti-oxidative effects and the underlying mechanisms of Ligusticum chuanxiong in neuronal cells |
Investigator(s): | Li CB, Lau ASY |
Department: | Medical Faculty |
Source(s) of Funding: | Seed Funding Programme for Basic Research |
Start Date: | 04/2011 |
Completion Date: | 03/2013 |
Project Title: | Cellular Oncogene Dysregulation of Chemokine and Cytokine Expression in Influenza Virus Infection |
Investigator(s): | Li CB, Leon YY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
Start Date: | 09/2011 |
Project Title: | A role for proto-oncogene c-Myc in antibiotics-sensitive and -resistant bacteria-induced immune responses: a potential building block for the new treatment development |
Investigator(s): | Li CB |
Department: | Medical Faculty |
Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
Start Date: | 12/2011 |
Project Title: | Immunology 2013; The effects of HIV-1 Tat protein on mycobacterial infection |
Investigator(s): | Li CB |
Department: | Medical Faculty |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 05/2013 |
List of Research Outputs |
LING W.L., WANG L., PONG C.H., Lau A.S.Y. and Li C.B., A role of IL-17A in modulating intracellular survival of Mycobacterium bovis BCG in murine macrophages, Immunology. 2013. |
Researcher : Li L |
Project Title: | 14th Asian Pacific Congress of Pediatrics (14th APCP 2012) & 4th Asia Pacific Congress of Pediatric Nursing; A validation study of the Chinese version of Early Development Instrument (CEDI): measurement of holistic development of Hong Kong children across different socioeconomic background |
Investigator(s): | Li L |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 09/2012 |
Completion Date: | 09/2012 |
List of Research Outputs |
Ip P., Wong W.H.S. and Li L., Child Abuse in Hong Kong and the Importance of Building an Effective Surveillance System in Chinese Societies, Nova Science Publishers, Inc. New York, 2013, 265-280. |
Researcher : Li S |
List of Research Outputs |
Yu W., Li S., Chan G.C.F., Ha S.Y., Wong S.J. and Cheung Y.F., Transmural strain and rotation gradient in survivors of childhood cancers, European Heart Journal Cardiovascular Imaging . 2012, 14: 175-182. |
Researcher : Ling MT |
List of Research Outputs |
Chong W.P., Ling M.T., Liu Y., Tu W. and Lau Y.L., Essential Role of NK Cells in IgG Therapy for Experimental Autoimmune Encephalomyelitis, Plos One. 2013. |
Researcher : Liu APY |
Project Title: | Language and Communication in Genetic Counseling for Sudden Arrhythmia Death Syndromes (SADS) in Hong Kong: An Exploratory Study |
Investigator(s): | Liu APY, Chung BHY, Chau AKT, Yung TC, Zayts OA |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 01/2012 |
Project Title: | Copy-number variations in Chinese patients with conotruncal defects |
Investigator(s): | Liu APY, Wong WL, Chung BHY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 06/2013 |
List of Research Outputs |
Ho C.C.A., Liu A.P.Y., Lun K.S., Tang W.F., Chan Y.K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aortic stenosis, microcephaly and dysmorphic facial features - Is cardiac assessment necessary for all patients with 17p13.3 microduplication?, European Journal of Medical Genetics. 2012, 55: 758-762. |
Ho C.C.A., Liu A.P.Y., Lun K.S. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aotic stenosis, microcephaly and dysmorphic facial features - is caridac assessment necessary for all patients with 17p13.3 microdup, [Case Report] London Dysmorphology & Neurogenetics Databases. 2012. |
Leung W.Y., Liu A.P.Y. and Chung B.H.Y., [Clinical Quiz] What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2012, 17(3): 190. |
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318. |
Researcher : Liu Y |
List of Research Outputs |
Chong W.P., Ling M.T., Liu Y., Tu W. and Lau Y.L., Essential Role of NK Cells in IgG Therapy for Experimental Autoimmune Encephalomyelitis, Plos One. 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., Human CD8 regulatory T cells inhibit graft-versus-host disease and preserve general immunity in humanized mice, Science Translational Medicine. 2013. |
Zheng J., Liu Y., liu M., Lau Y.L. and Tu W., Human CD8 regulatory T cells inhibit graft-versus-host disease and preserve general immunity in humanized mice, Science Translational Medicine . 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., unpolished sword in human antiviral Immunity, Cellular and Molecular Immunology. 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., γδ-T cells: an unpolished sword in human anti-infection immunity, Cellular and Molecular Immunology. 2013, 10: 50-57. |
Researcher : Low LCK |
Project Title: | 12th Asia Pacific Congress of Paediatrics and 2nd Asia Pacific Congress of Paediatric Nursing The Role of Nutritional Intake and Total Energy Expenditure on Early Growth of Babies Born with Intrauterine Growth Retardation |
Investigator(s): | Low LCK |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 09/2006 |
Researcher : Lun KS |
List of Research Outputs |
Chow P.C., Chan K.W., Lun K.S., Yung T.C., Cheung Y.F. and Chau A.K.T., Outcome of pregnancy in women with congential heart diseases (CHD) of a tertiary centre in Hong Kong, 21st Annual Scientific Scientific Congress, Hong Kong College of Cardiology, 8 June 2013. |
Ho C.C.A., Liu A.P.Y., Lun K.S., Tang W.F., Chan Y.K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aortic stenosis, microcephaly and dysmorphic facial features - Is cardiac assessment necessary for all patients with 17p13.3 microduplication?, European Journal of Medical Genetics. 2012, 55: 758-762. |
Ho C.C.A., Liu A.P.Y., Lun K.S. and Chung B.H.Y., A newborn with a 790 kb chromosome 17p13.3 microduplication presenting with aotic stenosis, microcephaly and dysmorphic facial features - is caridac assessment necessary for all patients with 17p13.3 microdup, [Case Report] London Dysmorphology & Neurogenetics Databases. 2012. |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Koh C., Hong W.J., Yung T.C., Lun K.S., Wong S.J. and Cheung Y.F., Left ventricular torsional mechanics and diastolic function in congenital heart block with right ventricular pacing , International Journal of Cardiology. 2012, 160: 31-35. |
Man E., Lafferty K.A., Funke B.H., Lun K.S., Chan S.Y., Chau A.K.T. and Chung B.H.Y., NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy, BMJ Case Reports [doi:10.1136/bcr-2012-007529]. 2013. |
Researcher : Luo JC |
List of Research Outputs |
CHEN J., LEE V., Luo J.C., Chiang A.K.S., Hongeng S., Tan P.L., Tan A.M., Sanpakit K., Li C.F., Lee A.C., Chua H.C. and Okamoto Y., Allogeneic stem cell transplantation for children with acquired severe aplastic anaemia: a retrospective study by the Viva-Asia Blood and Marrow Transplantation Group, British Journal of Haematology. 2013, 162(3). |
Researcher : Man E |
List of Research Outputs |
Man E., Lafferty K.A., Funke B.H., Lun K.S., Chan S.Y., Chau A.K.T. and Chung B.H.Y., NGS identifies TAZ mutation in a family with X-linked dilated cardiomyopathy, BMJ Case Reports [doi:10.1136/bcr-2012-007529]. 2013. |
Researcher : Mao H |
List of Research Outputs |
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L. and Lau Y.L., Autosomal Dominant Gain-of-function STAT1 Mutation is a Novel Genetic Etiology of Penicillium Marneffei Infection , Asian Society for Pediatric Research 2013. |
Researcher : Ning J |
List of Research Outputs |
Ning J., Chan K.H. and Chiang A.K.S., Epstein-barr Virus (EBV) - specific CD4+ and CD8_ T Cell REsponses Shift from Targeting Lytic- to Latent-cycle Proteins with Concurrent Development of Increased Polyfunctionality from the Acute to Persistent Phase of EBV Infection, 17th Research Postgraduate Symposium, Dec 12-13, 2012. 216. |
Researcher : Or CT |
List of Research Outputs |
Yang L.H., Or C.T., Ho M.H.K. and Lau A.S.Y., Scientific basis of botanical medicine as alternative remedies for rheumatoid arthritis, Clinical Reviews in Allergy & Immunology. 2012, 2012: 1-17. |
Researcher : PONG CH |
List of Research Outputs |
LING W.L., WANG L., PONG C.H., Lau A.S.Y. and Li C.B., A role of IL-17A in modulating intracellular survival of Mycobacterium bovis BCG in murine macrophages, Immunology. 2013. |
Pong C.H., Li C.B., Yim H.C.H. and Lau A.S.Y., THE ROLE OF C-MYC IN REGULATING HIV-1 TAT PROTEIN INDUCED CYTOKINE EXPRESSION AND CONSEQUENT EFFECTS ON OPPORTUNISTIC INFECTION, 10th Joint Annual Meeting of the International Cytokine Society (ICS) and the International Society for Interferon and Cytokine Research (ISICR). 2012. |
Researcher : Pong CH |
List of Research Outputs |
LING W.L., WANG L., PONG C.H., Lau A.S.Y. and Li C.B., A role of IL-17A in modulating intracellular survival of Mycobacterium bovis BCG in murine macrophages, Immunology. 2013. |
Pong C.H., Li C.B., Yim H.C.H. and Lau A.S.Y., THE ROLE OF C-MYC IN REGULATING HIV-1 TAT PROTEIN INDUCED CYTOKINE EXPRESSION AND CONSEQUENT EFFECTS ON OPPORTUNISTIC INFECTION, 10th Joint Annual Meeting of the International Cytokine Society (ICS) and the International Society for Interferon and Cytokine Research (ISICR). 2012. |
Researcher : Robles JD |
List of Research Outputs |
Robles J.D., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Norovirus infection in pediatric hematopoietic stem cell transplant recipients: incidence, risk factors and outcome, Biology of Blood and Marrow Transplant. 2012, in press. |
Researcher : Tan TY |
List of Research Outputs |
Tang M.H.Y., Lau E.T.K., Tan T.Y., Chung B.H.Y. and Shek N.W.M., Prenatal Diagnosis of Agenesis of the Corpus Callosum and Cerebellar Vermian Hypoplasia Associated with a Microdeletion on Chromosome 1p32: Decision Minor revision, Case Reports in Perinatal Medicine. 2013, 2;1-2: 39-45. |
Researcher : Tao QV |
List of Research Outputs |
Chung B.H.Y., Tao Q.V. and Tso W.Y.W., Copy number variation and autism: New insights and clinical implications, Journal of the Formosan Medical Association. 2013, 1-9. |
Researcher : Tso WWY |
Project Title: | Genetic basis of autism and macrocephaly |
Investigator(s): | Tso WYW, Wong VCN, Fung CW |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Seed Funding Programme for Basic Research |
Start Date: | 03/2012 |
List of Research Outputs |
Researcher : Tso WYW |
Project Title: | Genetic basis of autism and macrocephaly |
Investigator(s): | Tso WYW, Wong VCN, Fung CW |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Seed Funding Programme for Basic Research |
Start Date: | 03/2012 |
List of Research Outputs |
Chung B.H.Y., Tao Q.V. and Tso W.Y.W., Copy number variation and autism: New insights and clinical implications, Journal of the Formosan Medical Association. 2013, 1-9. |
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318. |
Researcher : Tu W |
Project Title: | Humanized mouse as a model to study the antiviral activity of human gammadelta-T cells against human and avian influenza A viruses in vivo |
Investigator(s): | Tu W, Lau YL, Peiris JSM, Law HKW |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
Start Date: | 08/2007 |
Project Title: | Antiviral Activity of Human gammadelta-T Cells against Epstein-Barr Virus Infection |
Investigator(s): | Tu W, Lau YL, Liu Y, Tsao GSW |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 10/2011 |
Project Title: | Immune Evasion of Natural Killer Cells for Influenza Virus in Vivo |
Investigator(s): | Tu W, Lau YL, Mao H, Liu Y |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
Start Date: | 12/2011 |
Project Title: | Induction of tolerance by alloantigen-specific regulatory T cells in humanized mice and non-human primates |
Investigator(s): | Tu W, Lau YL, Liu Y |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
Start Date: | 01/2012 |
List of Research Outputs |
Chong W.P., Ling M.T., Liu Y., Tu W. and Lau Y.L., Essential Role of NK Cells in IgG Therapy for Experimental Autoimmune Encephalomyelitis, Plos One. 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., Human CD8 regulatory T cells inhibit graft-versus-host disease and preserve general immunity in humanized mice, Science Translational Medicine. 2013. |
Zheng J., Liu Y., liu M., Lau Y.L. and Tu W., Human CD8 regulatory T cells inhibit graft-versus-host disease and preserve general immunity in humanized mice, Science Translational Medicine . 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., unpolished sword in human antiviral Immunity, Cellular and Molecular Immunology. 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., γδ-T cells: an unpolished sword in human anti-infection immunity, Cellular and Molecular Immunology. 2013, 10: 50-57. |
feng T., yin Z., li J., Tu W. and li H., Optimization of culture conditions for culturing of influenza virus H1N1 in MDCK cells and its purification, Journal of Pathogen Biology. 2012. |
li H., XIANG Z., feng T. and Tu W., Human Vγ9Vδ2-T cells efficiently kill influenza virus-infected lung alveolar epithelial cells, Cellular and Molecular Immunology . 2013. |
li J., li H., mo H., Tu W. and mao M., Vγ9Vδ2-T lymphocytes have impaired antiviral function in small-for-gestational-age and preterm neonates, Cellular and Molecular Immunology. 2013. |
xiong F., tong Y., you Y., Tu W. and mao M., Prospective cohort study about the lymphocyte subpopulations'change and impact on the pregnancy outcome in fetal growth restriction, Journal of Maternal-Fetal & Neonatal Medicine. 2012. |
Researcher : WANG L |
List of Research Outputs |
LING W.L., WANG L., PONG C.H., Lau A.S.Y. and Li C.B., A role of IL-17A in modulating intracellular survival of Mycobacterium bovis BCG in murine macrophages, Immunology. 2013. |
Researcher : Wong KT |
List of Research Outputs |
Ho C.C.A., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Lo I.F.M., Lam S.T.S., Chau A.K.T., Lau Y.L. and Chung B.H.Y., Two Chinese Patients with Loeys-Dietz Syndrome: A Connecitve Tissue Disorder with Marfan-like Features and Vasculopathy, Hong Kong Journal of Paediatrics (new series). 2012, 17: 248-253. |
Researcher : Wong KY |
List of Research Outputs |
Liu A.P.Y., Tang W.F., Lau E.T.K., Chan Y.K., Kan S.Y.A., Wong K.Y., Tso W.Y.W., Jalal K., Lee S.L., Chau C.S.K. and Chung B.H.Y., Expanded Prader-Willi Syndrome Due to Chromosome 15q11.2-14 Deletion: Report and a Review of Literature, American Journal of Medical Genetics, Part A. 2013, 161A: 1309-1318. |
Researcher : Wong PTY |
List of Research Outputs |
Wong P.T.Y. and Wong V.C.N., Pilot Study for Subgroup Classification for Autism Spectrum Disorder based on Dysmorphology and Physical Measurements in Chinese Children, 25th Annual Scientific Meeting of The Hong Kong Neurological Society. 2012. |
Researcher : Wong RMS |
List of Research Outputs |
Chow C.B., Ip P., Wong R.M.S. and Chan G.C.F., Submission to Panel on Health Services on the regulation of formula products and foods for infants and young children. Letter of recommendations to Hong Kong Legislative Council, LC Paper No. CB(2)213/12-13(03), Legislative Council, Hong Kong, 20 November 2012., 2012. |
Researcher : Wong SJ |
List of Research Outputs |
Chen R.H.S., Wong S.J., Wong W.H.S. and Cheung Y.F., Left ventricular contractile reserve after arterial switch operation for complete transposition of the great arteries: an exercise echocardiographic study , European Heart Journal - Cardiovascular Imaging doi:10.1093/ehjci/jes204. 2012, 14(5): 480-486. |
Cheung Y.F., Yu W., Li S.N., Lam W.W.M., Ho Y.C., Wong S.J., Chan G.C.F. and Ha S.Y., Dynamic dyssynchrony and impaired contractile reserve of the left ventricle in beta-thalassaemia major: an exercise echocardiographic study , PLOS One . 2012, 7: e45265. |
Koh C., Hong W.J., Yung T.C., Lun K.S., Wong S.J. and Cheung Y.F., Left ventricular torsional mechanics and diastolic function in congenital heart block with right ventricular pacing , International Journal of Cardiology. 2012, 160: 31-35. |
Yu H.K., Yu W., Cheuk K.L.D., Wong S.J., Chan G.C.F. and Cheung Y.F., New 3D speckle tracking echocardiography identifies global impairment of left ventricular mechanics with a high sensitivity in childhood cancer survivors , J Am Soc Echocardiogr. 2013, 26: 846-52. |
Yu W., Li S., Chan G.C.F., Ha S.Y., Wong S.J. and Cheung Y.F., Transmural strain and rotation gradient in survivors of childhood cancers, European Heart Journal Cardiovascular Imaging . 2012, 14: 175-182. |
Researcher : Wong SN |
List of Research Outputs |
Li P.H., Wong W.H.S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Tong K.L., Tse N.K.C., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chong C.Y., Wong R.W.S., Mok T.M.Y., Ying S.K.Y., Fung S.K.S., Lai W.M., Yang W. and Lau Y.L., Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology. Oxford, 2013, 52(2): 337-345. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : Wong VCN |
Project Title: | Rett Syndrome :Systematic screening of MECP2 in children with autistic traits and or unexplained mental retardation/ encephalopathy to define the spectrum of Rett Syndrome phenotypes resulting from mutations in MECP2 |
Investigator(s): | Wong VCN |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 01/2006 |
Project Title: | Single-blinded, randomized, and placebo-controlled trial in FMR1 KO and WT mice |
Investigator(s): | Wong VCN |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 04/2011 |
Completion Date: | 03/2013 |
Project Title: | Genetic analysis of PCDH19 and TSPYL mutation in Chinese children with GEFS+ and Dravet Syndromeencephaolpathy |
Investigator(s): | Wong VCN, Kwong KY, Fung CW, Chan SY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 05/2012 |
Project Title: | Joint 12th International Child Neurology Congress and 11th Asian and Oceanian Congress of Child Neurology Dravet Syndrome: Genetic analysis of SCN1A and PCDH19 Mutations for 17 Chinese children |
Investigator(s): | Wong VCN |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 05/2012 |
Project Title: | Mutation analysis of CDKL5, STXBP1 and GABA receptor subunit genes in Chinese children with infantile spasms (IS) |
Investigator(s): | Wong VCN, Kwong KY, Fung CW |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 06/2013 |
List of Research Outputs |
Chan S.H.S., Wong V.C.N. and Engel A.G., Neuromuscular junction acetylcholinesterase deficiency responsive to albuterol, Pediatric Neurology. 2012, 47(2): 137-140. |
Cheuk K.L.D., Yeung W.F., Chung K.F. and Wong V.C.N., Acupuncture for insomnia, cochrane Database of Systematic Reviews 2012 . 2012, 9: 1-181. |
Cheuk K.L.D., Wong V.C.N., Wraige E., Baxter P. and Cole A., Surgery for scoliosis in Duchenne muscular dystrophy, Cochrane Database of Systematic Reviews. 2013, 2: 1-40. |
Kwong K.Y., Fung C.W., Chan S.Y. and Wong V.C.N., Identification of SCN1A and PCDH19 Mutations in Chinese Children with Dravet Syndrome, PLoSOne. 2012, 7(7): e41802. |
Tsang J.P.K., Poon W.L., Luk H.M., Fung C.W., Ching C.K., Mak C.M., Lam C.W., Siu T.S., Tam S. and Wong V.C.N., Arginase deficiency with new phenotype and a novel mutation: Contemporary Summary, Pediatric Neurology. 2012, 47(4): 263-269. |
Wong P.T.Y. and Wong V.C.N., Pilot Study for Subgroup Classification for Autism Spectrum Disorder based on Dysmorphology and Physical Measurements in Chinese Children, 25th Annual Scientific Meeting of The Hong Kong Neurological Society. 2012. |
Wong S. and Wong V.C.N., Klein Levin Syndrome is a steroid-responsive, non-N-methyl-D-aspartate receptor-mediated encephalitis, 25th Annual Scientific Meeting of The Hong Kong Neurological Society. 3rd November 2012. |
Wong V.C.N., Cheuk K.L.D., Lee S. and Chu L.Y.V., Acupuncture for acute management and rehabilitation of traumatic brain injury, Cochrane Database of Systemic Review. John Wiley & Sons, Ltd., 2013, 3: 1-36. |
Wong V.C.N., Cheuk K.L.D. and Chu L.Y.V., Acupuncture for hypoxic ischemic encephalopathy in neonates, Cochrane Database of Systematic Reviews. 2013, 1: 1-22. |
Wong V.C.N., Kwong K.Y. and Fung C.W., Dravet Syndeome - Genetic Analysis of SCN1A and PCDH19 Mutations for 17 Chinese Children, 25th Annual Scientific Meeting of The Hong Kong Neurological Society. 3rd November 2012. |
Wong V.C.N., Editorial Board Member (Since 2001), Pediatrics International. 2012. |
Wong V.C.N., Editorial Board Member (Since 2003), Brain & Development. 2012. |
Wong V.C.N., Editorial Board Member (Since 2003), Journal of Pediatric Neurology. 2012. |
Wong V.C.N., Editorial Board Member (Since 2012), Evidence-Based Complementary and Alternative Medicine. 2013. |
Wong V.C.N., Editorial Board Member (Since 2012), Journal of Autism and Developmental Disorders. 2013. |
Wong V.C.N., Editorial Board Member (since 2010), BMC Medicine. 2012. |
Wong V.C.N., Editorial Board Member (since 2010), BMC Medicine. 2012. |
Wong V.C.N., Reviewer (Since 1987), Brain & Development. 2012. |
Wong V.C.N., Reviewer (Since 2003), BMJ. 2012. |
Wong V.C.N., Reviewer (Since 2007), Pediatric Rehabilitation/Developmental Neurorehabilitation. 2012. |
Wong V.C.N., Reviewer (Since 2007), Pediatric Rehabilitation/Developmental Neurorehabilitation. 2012. |
Researcher : Wong WHS |
List of Research Outputs |
Chen H.S.R., Wong W.H.S. and Cheung Y.F., Vascular mechanics at rest and during exercise after arterial switch operation for complete transposition of the great arteries, Hong Kong College of Cardiology, Twenty-first Annual Scientific Congress, Hong Kong, 7 - 9 June 2013. . 2013. |
Chen R.H.S., Wong S.J., Wong W.H.S. and Cheung Y.F., Left ventricular contractile reserve after arterial switch operation for complete transposition of the great arteries: an exercise echocardiographic study , European Heart Journal - Cardiovascular Imaging doi:10.1093/ehjci/jes204. 2012, 14(5): 480-486. |
Ho M.H.K., Wong W.H.S. and Chang C., Clinical Spectrum of Food Allergies: a Comprehensive Review, Clinical Reviews in Allergy & Immunology. Springer, 2012, 41(3). |
Ho M.H.K., Lee S.L., Wong W.H.S., Ip P. and Lau Y.L., Prevalence of self-reported food allergy in Hong Kong children and teens - a population survey, Asian Pacific Journal of Allergy Immunology. 2012, 30(4): 275-284. |
Ip P., Wong W.H.S. and Li L., Child Abuse in Hong Kong and the Importance of Building an Effective Surveillance System in Chinese Societies, Nova Science Publishers, Inc. New York, 2013, 265-280. |
Lee S.L., Cheung Y.F., Wong W.H.S., Leung T.H., Lam T.H. and Lau Y.L., Chronic health problems and health-related quality of life in Chinese children and adolescents: a population-based study in Hong Kong., British Medical Journal Open . 2013, 3: e001183.doi:10.1136/bmjopen-2012-001183. |
Lee S.L., Lam T.H., Leung T.H., Wong W.H.S., Schooling M., Leung G.M. and Lau Y.L., Foetal Exposure to Maternal Passive Smoking Is Associated with Childhood Asthma, Allergic Rhinitis, and Eczema, Scientific World Journal. 2012, 2012: 1-9. |
Li P.H., Wong W.H.S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Tong K.L., Tse N.K.C., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chong C.Y., Wong R.W.S., Mok T.M.Y., Ying S.K.Y., Fung S.K.S., Lai W.M., Yang W. and Lau Y.L., Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology. Oxford, 2013, 52(2): 337-345. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : XIANG Z |
List of Research Outputs |
li H., XIANG Z., feng T. and Tu W., Human Vγ9Vδ2-T cells efficiently kill influenza virus-infected lung alveolar epithelial cells, Cellular and Molecular Immunology . 2013. |
Researcher : Yang J |
List of Research Outputs |
Yang J., Yang W. and Lau Y.L., Gene-gene Interaction In Disease Association For Systemic Lupus Erythematosus In Asian Populations. , American Society Of Human Genetics, 2012. |
Yang J., Cheuk K.L.D., Ha S.Y., Chiang A.K.S., Lee T.L., Ho M.H.K. and Chan G.C.F., Infliximab for steroid refractory or dependent gastrointestinal acute graft-versus-host disease in children after allogeneic hematopoietic stem cell transplantation, Pediatr Transplant. 2012, 16(7): 771-8. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Zhang L., Zhang J., Yang J., Ying D., Lau Y.L. and Yang W., PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data, Bioinformatics. 2013, 29(1): 124-125. |
Researcher : Yang LH |
Project Title: | Discovery and Validation of antiviral small-molecule inhibitors for influenza virus replication |
Investigator(s): | Yang LH, Law HY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
Start Date: | 02/2012 |
Researcher : Yang M |
Project Title: | Protective effect of thrombopoietin on iron-induced cardiomyopathy |
Investigator(s): | Yang M |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
Start Date: | 07/2007 |
Project Title: | The effect of melatonin in the treatment of thrombocytopenia |
Investigator(s): | Yang M |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme |
Start Date: | 01/2008 |
Project Title: | The protective effects of thrombopoietin and amlodipine on iron overload-induced human mesenchymal stem cell damage: its impact on iron overload related osteopenia & osteoporosis |
Investigator(s): | Yang M, Chan GCF, Cheung YF, Liu C |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
Start Date: | 01/2009 |
Researcher : Yang W |
Project Title: | Meta-Analysis of two Asian GWAS datasets for identification of novel genetic variants associated with systemic lupus erythematosus |
Investigator(s): | Yang W, Lau YL, Sham PC, Yang J |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | General Research Fund (GRF) |
Start Date: | 10/2011 |
Project Title: | Verification of X-linked genes as risk loci for systemic lupus erythematosus |
Investigator(s): | Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Seed Funding Programme for Basic Research |
Start Date: | 05/2012 |
Project Title: | American society of human genetics annual meeting; Association study on the X chromosome identifies novel genes associated with systemic lupus erythematosus (SLE) in Asian populations |
Investigator(s): | Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 11/2012 |
Project Title: | Gene-based meta-analysis and further replication of SLE susceptibility genes in Asians |
Investigator(s): | Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Seed Funding Programme for Basic Research |
Start Date: | 06/2013 |
List of Research Outputs |
Kaiser R., Kaiser R., Taylor K.E., Deng Y., Zhao J., Li Y., Nititham J., Chang M., Catanese J., Begovich A.B., Brown E.E., Edberg J.C., McGwin G., Alarcon G.S., Ramsey-Goldman R., Reveille J.D., Vila L.M., Petri M., Kimberly R.P., Feng X., Sun L., Shen N., Li W., Lu J.X., Wakeland E.K., Li Q.Z., Yang W., Lau Y.L., Liu F.L., Chang D.M., Yu C.Y., Song Y.W., Tsao B.P. and Criswell L.A., Single-Nucleotide Polymorphisms in VKORC1 Are Risk Factors for Systemic Lupus Erythematosus in Asians, Arthritis & Rheumatism. 2013, 65(1): 211-215. |
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L. and Lau Y.L., Autosomal Dominant Gain-of-function STAT1 Mutation is a Novel Genetic Etiology of Penicillium Marneffei Infection , Asian Society for Pediatric Research 2013. |
Lee P.P.W., He J.X., Chan K.W., Yang W., Jiang L.P., Liew W.K., Chen T.X., Ho M.H.K., Lee T.L. and Lau Y.L., Unique Pattern of Infections in Chronic Granulomatous Disease – The Asian Experience, Asian Society for Pediatric Research 2013. |
Li M., Kwan S.H., Bao S., Yang W., Ho S.L., Song Y. and Sham P.C., Predicting Mendelian Disease-Causing Non-Synonymous Single Nucleotide Variants in Exome Sequencing Studies, PLos Genet. 2013, 9(1): e1003143. |
Li P.H., Wong W.H.S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Tong K.L., Tse N.K.C., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chong C.Y., Wong R.W.S., Mok T.M.Y., Ying S.K.Y., Fung S.K.S., Lai W.M., Yang W. and Lau Y.L., Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese, Rheumatology. Oxford, 2013, 52(2): 337-345. |
Wong E.H.M., Cui L., Ng C.L., Tang S.M., Liu X., So M.T., Yip B.H.K., Cheng G., Zhang R., Tang W.K., Yang W., Lau Y.L., Baum L., Kwan P., Sun L.D., Zuo Z.B., Ren Y.Q., Yin X.Y., Miao X., Liu J.J., Lui V.C.H., Ngan E.S.W., Yuan Z.W., Zhang S.W., Xia J.L., Wang H.L., Sun X.B., Wang R.Y., Chang T., Chan I.H.Y., Chung H.Y., Zhang X.J., Wong K.K.Y., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number variation study in anorectal malformations, Human Molecular Genetics. 2013, 22(3): 621-631. |
Yang J., Yang W. and Lau Y.L., Gene-gene Interaction In Disease Association For Systemic Lupus Erythematosus In Asian Populations. , American Society Of Human Genetics, 2012. |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Zhang L., Zhang J., Yang J., Ying D., Lau Y.L. and Yang W., PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data, Bioinformatics. 2013, 29(1): 124-125. |
Zhao H., Yang W., Qiu R., Li J., Xin Q., Wang X., Feng Y., Shan S., Liu Y., Gong Y. and Liu Q., An intronic variant associated with systemic lupus erythematosus changes the binding affinity of Yinyang1 to downregulate WDFY4, Genes and Immunity. 2012, 13(7): 536-542. |
Researcher : Yick LW |
Project Title: | Defining the roles of epidermal growth factor (EGF) in the regulation of chondrocyte differentiation and endochondral bone formation |
Investigator(s): | Yick LW, Chan SY |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 11/2004 |
Researcher : Ying D |
List of Research Outputs |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Zhang L., Zhang J., Yang J., Ying D., Lau Y.L. and Yang W., PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data, Bioinformatics. 2013, 29(1): 124-125. |
Researcher : Yu W |
List of Research Outputs |
Yu W., Li S., Chan G.C.F., Ha S.Y., Wong S.J. and Cheung Y.F., Transmural strain and rotation gradient in survivors of childhood cancers, European Heart Journal Cardiovascular Imaging . 2012, 14: 175-182. |
Researcher : Yung TC |
List of Research Outputs |
Chow P.C., Chan K.W., Lun K.S., Yung T.C., Cheung Y.F. and Chau A.K.T., Outcome of pregnancy in women with congential heart diseases (CHD) of a tertiary centre in Hong Kong, 21st Annual Scientific Scientific Congress, Hong Kong College of Cardiology, 8 June 2013. |
Koh C., Hong W.J., Yung T.C., Lun K.S., Wong S.J. and Cheung Y.F., Left ventricular torsional mechanics and diastolic function in congenital heart block with right ventricular pacing , International Journal of Cardiology. 2012, 160: 31-35. |
Yung T.C. and Yu T.C., Catecholaminergic Polymorphic Ventricular Tachycardia in Chinese Children, 21st Annual Scientific Scientific Congress, Hong Kong College of Cardiology, 8 June 2013. |
Researcher : ZHANG J |
List of Research Outputs |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Zhang L., Zhang J., Yang J., Ying D., Lau Y.L. and Yang W., PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data, Bioinformatics. 2013, 29(1): 124-125. |
Researcher : Zeng S |
List of Research Outputs |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : Zhang J |
List of Research Outputs |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Zhang L., Zhang J., Yang J., Ying D., Lau Y.L. and Yang W., PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data, Bioinformatics. 2013, 29(1): 124-125. |
Researcher : Zhang L |
List of Research Outputs |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Zhang L., Zhang J., Yang J., Ying D., Lau Y.L. and Yang W., PriVar: a toolkit for prioritizing SNVs and indels from next-generation sequencing data, Bioinformatics. 2013, 29(1): 124-125. |
Researcher : Zhang Y |
Project Title: | Gene-gene Epistatic interaction study for systemic lupus erythematosus |
Investigator(s): | Zhang Y, Yang W |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | Small Project Funding |
Start Date: | 02/2013 |
List of Research Outputs |
Yang W., Tang H., Zhang Y., Tang X., ZHANG J., Sun L., Yang J., Cui Y., Zhang L., Hirankarn N., Cheng H., Pan H.F., Gao J., Lee T.L., Sheng Y., Lau W.C.S., Li Y., Chan T.M., Yin X., Ying D., Lu Q., Leung A.M.H., Zuo X., Chen X., Tong K.L., Zhou F., Diao Q., Tse N.K.C., Xie H., Mok C.C., Hao F., Wong S.N., Shi B., Lee K.W., Hui Y., Ho M.H.K., Liang B., Lee P.P.W., Cui H., Guo Q., Chung B.H.Y., Pu X., Liu Q., Zhang X., Zhang C., Chong C.Y., Fang H., Wong R.W.S., Sun Y., Mok T.M.Y., Li X.P., Avihingsanon Y., Zhi Z., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Gao F., Shotelersuk V., Kang X., Ying S.K.Y., Zhang L., Wong W.H.S., Zhu D., Fung S.K.S., Zeng F., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Shen N., Tam P.K.H., Sham P.C., Ye D.Q., Yang S., Zhang X. and Lau Y.L., Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians, The American Journal of Human Genetics. 2013, 92: 41-51. |
Zhang J., Zhang Y., Zhang L., Yang J., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Lau Y.L. and Yang W., Epistatic Interaction between Genetic Variants in Susceptibility Gene ETS1 Correlates with IL-17 Levels in SLE Patients, Annals of Human Genetics. 2013, 77(4): 344-350. |
Researcher : Zheng J |
Project Title: | european congress of immunology 2012 ICOS-ICOSL regulates the generation and function of CD4+ Treg in a CTLA-4 dependent manner |
Investigator(s): | Zheng J |
Department: | Paediatrics & Adolescent Med |
Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
Start Date: | 09/2012 |
List of Research Outputs |
Zheng J., Liu Y., Lau Y.L. and Tu W., Human CD8 regulatory T cells inhibit graft-versus-host disease and preserve general immunity in humanized mice, Science Translational Medicine. 2013. |
Zheng J., Liu Y., liu M., Lau Y.L. and Tu W., Human CD8 regulatory T cells inhibit graft-versus-host disease and preserve general immunity in humanized mice, Science Translational Medicine . 2013. |
Zheng J., travelship, NIF winter school. 2012. |
Zheng J., Liu Y., Lau Y.L. and Tu W., unpolished sword in human antiviral Immunity, Cellular and Molecular Immunology. 2013. |
Zheng J., Liu Y., Lau Y.L. and Tu W., γδ-T cells: an unpolished sword in human anti-infection immunity, Cellular and Molecular Immunology. 2013, 10: 50-57. |