DEPT OF PHARMACOLOGY & PHARMACY
| Researcher : Anand S |
| List of Research Outputs |
| Anand S., Tong H.Y.H., Besag F.M.C., Chan E.W., Cortese S. and Wong I.C.K., Safety, Tolerability And Efficacy Of Drugs For Treating Behavioural Insomnia In Children With Attention-deficit/hyperactivity Disorder: A Systematic Review With Methodological Quality Assessment. , Pediatr Drugs . 2017, 19(3): 235-250. |
| Chung A.Y., Anand S., Wong I.C.K., Tan K.C.B., Wong C.F., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong: a multidisciplinary approach, Hong Kong Medical Journal. 2017, 23(2): 158-67. |
| Chung A.Y.S., Anand S., Wong I.C.K., Tan K.C.B., Wong F.F.C., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong – A multi-disciplinary approach., Hong Kong Med. J. . 2017, 23(2): 158-167. |
| He Y.H., Wong I.C.K., Li X., Anand S., Leung W.K., Siu D.C.W. and Chan E.W., The association between non-vitamin K antagonist oral anticoagulants and gastrointestinal bleeding: a meta-analysis of observational studies, British Journal of Clinical Pharmacology. 2016, 82(1): 285-300. |
| WONG Y.S., Chan E.W., Anand S., Worsley A.J. and Wong I.C.K., Managing cardiovascular risk of macrolides: systematic review and meta-analysis. , Drug Saf . 2017. |
| Researcher : Baretella OM |
| List of Research Outputs |
| Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice, Acta Pharmacologica Sinica. 2017, 38: 498-512. |
| Researcher : CAO H |
| List of Research Outputs |
| CAO H., Aggressive Breast Cancer Development in Adiponectin-deficient PyVT-MMTV Mice-Role of Thymus Dysfunction, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| LI D., CAO H., CHEN J. and Wang Y., Adiponectin-based Therapeutics in Cancer Treatment, Frontiers in Clinical Drug Research - Anti-Cancer Agents. Bentham Science, 2017, 4: 1-52. |
| Researcher : CHEN H |
| List of Research Outputs |
| CHEN H. and Leung S.W.S., AMPK Activator Inhibits EDH-like Relaxations in Superior Mesenteric Arteries of Rats, 12th International Symposium on Healthy Aging, 11-12 March 2017, Hong Kong. 2017. |
| Researcher : CHEN J |
| List of Research Outputs |
| CHEN J. and Woo W.H.C., Metabolic Function of TIR-Domain-containing Adaptor-inducing Interferon-b (TRIF) in Diet-induced obesity, The University of Hong Kong. 2016. |
| CHEN J., LI J., Xu A. and Woo W.H.C., Metabolic Function of TIR-Domain-containing adapter-inducing interferon-b (TRIF) in hepatocytes, In: Federation of American Societies for Experimental Biology, FASEB Science Research Conference: Immunological Aspects of Obesity. 2016. |
| CHEN J., Li J., Xu A. and Woo W.H.C., Metabolic function of TIR-domain-containing adapter-inducing interferon-b (TRIF) in hepatocytes, FASEB Science Research Conferences, July 31- August 5, 2016, Big Sky, Montana. 2016. |
| LI D., CAO H., CHEN J. and Wang Y., Adiponectin-based Therapeutics in Cancer Treatment, Frontiers in Clinical Drug Research - Anti-Cancer Agents. Bentham Science, 2017, 4: 1-52. |
| Researcher : CHEN J |
| List of Research Outputs |
| CHEN J. and Woo W.H.C., Metabolic Function of TIR-Domain-containing Adaptor-inducing Interferon-b (TRIF) in Diet-induced obesity, The University of Hong Kong. 2016. |
| CHEN J., LI J., Xu A. and Woo W.H.C., Metabolic Function of TIR-Domain-containing adapter-inducing interferon-b (TRIF) in hepatocytes, In: Federation of American Societies for Experimental Biology, FASEB Science Research Conference: Immunological Aspects of Obesity. 2016. |
| CHEN J., Li J., Xu A. and Woo W.H.C., Metabolic function of TIR-domain-containing adapter-inducing interferon-b (TRIF) in hepatocytes, FASEB Science Research Conferences, July 31- August 5, 2016, Big Sky, Montana. 2016. |
| LI D., CAO H., CHEN J. and Wang Y., Adiponectin-based Therapeutics in Cancer Treatment, Frontiers in Clinical Drug Research - Anti-Cancer Agents. Bentham Science, 2017, 4: 1-52. |
| Researcher : CHENG KF |
| List of Research Outputs |
| Cheung C.L., Ho D.K., SING C.W., TSOI M.F., CHENG K.F., LEE K.Y., Ho Y.N. and Cheung B.M.Y., Randomized controlled trial of the effect of phytosterols-enriched low-fat milk on lipid profile in Chinese, Scientific Reports. 2017, 7: 41084. |
| Wong H.Y., CHENG K.F., LEE K.Y. and Cheung C.L., Plenary Oral Presentation Award, Korean Endocrine Society. 2017. |
| Wong H.Y., CHENG K.F., LEE K.Y. and Cheung C.L., Precision Medicine of Denosumab Monotherapy in Osteoporotic Patients, The 5th Seoul International Congress of Endocrinology and Metabolism, SICEM 2017. |
| Researcher : CHEONG LY |
| List of Research Outputs |
| CHEONG L.Y., Absence of Inguinal Lymph Nodes Impairs the Browning of White Adipose Tissue, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| SHU L., Hoo R.L.C., WU X., PAN Y., LEE P.C., CHEONG L.Y., Bornstein S.R., Rong X., Gua J. and Xu A., A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes., Nature Communications. 2017. |
| Shu L., WU X., PAN Y., CHEONG L.Y., Xu A. and Hoo R.L.C., Adipocyte fatty acid binding protein (A-FABP) modulates adaptive thermogenesis by enhancing intracellular activation of thyroid hormones in brown adipocytes, 2016 International Congress on Obesity and Metabolic Syndrome in conjunction with the 45th Annual Scientific Meeting of KSSO . 2016. |
| WU X., Shu L., CHEONG L.Y., Lam K.S.L., Xu A. and Hoo R.L.C., The role of adipocyte fatty acid binding protein (A-FABP) in the pathogenesis of liver fibrosis, FASEB Science Research Conference. 2017. |
| Researcher : CHEUNG C |
| List of Research Outputs |
| Li Z., Li S., Hu L., Li F., CHEUNG C., SHao W., Que Y., Leung G.P.H. and Yang C., MECHANISMS UNDERLYING ACTION OF XINMAILONG INJECTION, A TRADITIONAL CHINESE MEDICINE, IN CARDIAC FUNCTION IMPROVEMENT, African Journal of Traditional, Complementary and Alternative medicines. 2017, 14: 241-252. |
| Researcher : CHOW YT |
| List of Research Outputs |
| CHOW Y.T., Formulation of Small Nucleic Acids into Inhalable Dry Powders with Manitol and L-leucine Using Spray Drying Technology, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| CHOW Y.T., Lin H.H.S. and Lam J.K.W., Optimisation of inhalable spray dried powder formulation of small nucleic acids with mannitol and leucine, Drug Delivery to the Lungs 27. 2016. |
| QIU Y., CHOW Y.T. and Lam J.K.W., Synthetic KL4 peptide as new carrier of siRNA therapeutics for pulmonary delivery, Drug Delivery to the Lungs 27. 2016. |
| Researcher : CHUI SLC |
| List of Research Outputs |
| CHUI S.L.C., WONG Y.S., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Potential association between the use of oral fluoroquinolones and acute neuropsychiatric disorders in Hong Kong: a self-controlled case series study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| CHUI S.L.C., Wong I.C.K., WONG Y.S., LEE E.H.M., CHANG W.C., CHEN E.Y.H. and Chan E.W., The Association Between the Use of Oral Fluoroquinolones and Neuropsychiatric Events: A Self-Controlled Case Series Study, 32nd ICPE, Dublin, August 25-28, 2016. |
| WONG Y.S., Wong I.C.K., CHUI S.L.C., LEE E.H.M., CHANG W.C., CHEN E.Y.H., LEUNG W.K. and Chan E.W., Neuropsychiatric Events Associated with the Use of Helicobacter Pylori Eradication Therapy Containing-Clarithromycin: Self-Controlled Case Series, 32nd ICPE, Dublin, August 26-28, 2016. |
| Researcher : Cai Y |
| List of Research Outputs |
| PANG L., Cai Y., Tang E.H.C., YAN D., Li H., IRWIN M.G., MA H., Xia Z. and RAMOJI K., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis via Akt-dependent enhancentment of iNOS expression, Oxidative Medicine and Cellular Longevity. 2016. |
| YING F., Cai Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 (EP4) regulates lipid droplet size and mitochondrial activity via FSP27 in white adipose tissue, Metabolic Diseases; Breakthrough Discoveries in Diabetes & Obesity, Novotel Melbourne St Kilda, 1-2 December 2016. |
| YING F., Cai Y., CAI Y., Wang Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 regulates lipid droplet size and mitochondrial activity in murine subcutaneous white adipose tissue, The FASEB Journal. 2017, 331: 4023-4036. |
| YING F., Cai Y. and Tang E.H.C., Prostaglandin receptor subtype 4 (EP4) deficiency enhanced multilocular fat cell formation and mitochondrial biogenesis and facilated wat remodeling, The 6th ICCR Congress on Chronic Societal Cardiometabolic Diseases, May 15-17, 2017, Quebec Canada. 2017. |
| Researcher : Chan EW |
| Project Title: | Intramuscular olanzapine versus haloperidol or midazolam for the management of acute agitation in the emergency department a multicentre randomised clinical trial. |
| Investigator(s): | Chan EW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Early Career Scheme (ECS) |
| Start Date: | 01/2014 |
| Project Title: | Young adult patient experiences in clinical management of ADHD in Hong Kong |
| Investigator(s): | Chan EW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Janssen Pharmaceutica - General Award |
| Start Date: | 01/2014 |
| Project Title: | Mother’s preferences and willingness to pay for human papillomavirus vaccination for their daughters: a discrete choice experiment in Hong Kong |
| Investigator(s): | Chan EW, McGhee S, Wong CKH, Ip DKM, Chau J, Wong ICK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2014 |
| Completion Date: | 04/2017 |
| Project Title: | Oro-dispersible olanzapine (wafer) versus conventional oral haloperidol or diazepam tablets for the management of acute agitation in the Accident and Emergency Department - a multicentre randomised clinical trial. |
| Investigator(s): | Chan EW, Leung LP |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 06/2016 |
| Project Title: | 32nd International Conference on Pharmacoepidemiology & Therapeutic Risk Management; 1. #1289 - Hospitalization and Length of Stay Among Patients with Non-Valvular Atrial Fibrillation Taking Dabigatran or Warfarin: A Population-Based Cohort Study/2. #1023 - Dabigatran versus Warfarin in Patients with Non-Valvular Atrial Fibrillation: A Population-Wide Cohort Study in Chinese Patients |
| Investigator(s): | Chan EW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 08/2016 |
| Completion Date: | 08/2016 |
| Project Title: | The prescribing trends and safety of biologics in Hong Kong |
| Investigator(s): | Chan EW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | Understanding drug abuser and their healthcare pathways: Towards better management in Hong Kong |
| Investigator(s): | Chan EW, Tam AW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Beat Drugs Fund Association |
| Start Date: | 06/2017 |
| List of Research Outputs |
| Anand S., Tong H.Y.H., Besag F.M.C., Chan E.W., Cortese S. and Wong I.C.K., Safety, Tolerability And Efficacy Of Drugs For Treating Behavioural Insomnia In Children With Attention-deficit/hyperactivity Disorder: A Systematic Review With Methodological Quality Assessment. , Pediatr Drugs . 2017, 19(3): 235-250. |
| Botzenhardt S., Wong I.C.K., Chan E.W., SING C.W. and Neubert A., Safety profiles of iron chelators in young patients with haemoglobinopathies, Eur J Haematol . 2017, 98(3): 198-217. |
| CHUI S.L.C., WONG Y.S., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Potential association between the use of oral fluoroquinolones and acute neuropsychiatric disorders in Hong Kong: a self-controlled case series study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| CHUI S.L.C., Wong I.C.K., WONG Y.S., LEE E.H.M., CHANG W.C., CHEN E.Y.H. and Chan E.W., The Association Between the Use of Oral Fluoroquinolones and Neuropsychiatric Events: A Self-Controlled Case Series Study, 32nd ICPE, Dublin, August 25-28, 2016. |
| Chan E.W., Emergency Geriatrics, Central Commissioned Training Program (HA , A & E COC) Hong Kong. 2016. |
| Chan E.W., Evidence-based management of acute agitation., Central commissioned training program by COC (A&E), Kowloon, Hong Kong. 2017. |
| Chan E.W., LAU C.Y., Leung W.K., Michael M.T.C., Ying H., Tong S.M. and Wong I.C.K., Faculty Outstanding Research Output Award, Faculty of Medicine, The University of Hong Kong. 2016. |
| Chan E.W., Press Release, HKU discovers that traditional blood thinner drug is associated with a higher risk of osteoporotic fracture compared to newer drug, 研究指長期使用傳統薄血藥可致骨折 嚴重或增死亡率, 2017. |
| Chan E.W., The management of acute agitation in the emergency setting., EMCORE Masterclass Hong Kong. 2017. |
| Chan P.H.M., Hai S.H.J.J., Huang D., Ho M.H., Chan E.W., Cheung B.M.Y., Wong I.C.K., Tse H.F., Hung F.N.I. and Siu D.C.W., Burden of upper gastrointestinal symptoms in patients prescribed Dabigatran for stroke prevention., Sage Open Medicine . 2016, 4:2050312116662414. |
| Chung A.Y., Anand S., Wong I.C.K., Tan K.C.B., Wong C.F., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong: a multidisciplinary approach, Hong Kong Medical Journal. 2017, 23(2): 158-67. |
| Chung A.Y.S., Anand S., Wong I.C.K., Tan K.C.B., Wong F.F.C., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong – A multi-disciplinary approach., Hong Kong Med. J. . 2017, 23(2): 158-167. |
| He Y.H., Wong I.C.K., Li X., Anand S., Leung W.K., Siu D.C.W. and Chan E.W., The association between non-vitamin K antagonist oral anticoagulants and gastrointestinal bleeding: a meta-analysis of observational studies, British Journal of Clinical Pharmacology. 2016, 82(1): 285-300. |
| LAO S., Chan E.W., Man K.C.K. and Wong I.C.K., Antipsychotic Prescription Trend in Hong Kong from 2004 to 2014, 32nd ICPE, Dublin, August 25-28, 2016. |
| LAO S., Tam A.W., Wong I.C.K., Besag F.M.C., Man K.C.K., Chui S.L.C. and Chan E.W., Prescribing trends and indications of antipsychotic medication in Hong Kong from 2004 to 2014: General and vulnerable patient groups, Pharmacoepidemiology and Drug Safety. 2017. |
| LAO S., He Y., Wong I.C.K., Besag F.M.C. and Chan E.W., Tolerability and safety profile of cariprazine in treating psychotic disorder, bipolar disorder and major depressive disorder: a systematic review with meta-analysis of randomised controlled trials., CNS Drugs. 2016, 30(11): 1043-1054. |
| LAO S., HE Y., Wong I.C.K., BESAG F.M.C. and Chan E.W., Tolerability/Safety Profile of Cariprazine in Treating Psychotic Disorders/Bipolar Disorder: A Systematic Review with Meta-Analysis of RCTs , 32nd ICPE, Dublin, August 25-28, 2016. |
| LAU C.Y., Chan E.W., Cheung C.L., SING C.W., Man K.C.K., Lip G.Y.H., Siu D.C.W., Lam K.Y.J., Lee C.H.A. and Wong I.C.K., Association Between Dabigatran vs Warfarin and Risk of Osteoporotic Fractures Among Patients With Nonvalvular Atrial Fibrillation, JAMA. 2017, 317: 1151. |
| LAU C.Y., Li X., Wong I.C.K. and Chan E.W., Bleeding-related hospital admissions and 30-day readmission with dabigatran versus warfarin in patients with non-valvular atrial fibrillation, ISPOR, Boston USA, 20-24th May (Poster) 2017. |
| LAU C.Y., Chan E.W. and Wong I.C.K., Dabigatran versus Warfarin in Patients with Non-Valvular Atrial Fibrillation: A Population-Wide Cohort Study in Chinese Patients. , ICPE, Dublin, Ireland, 25-28th August.. 2016. |
| LAU C.Y., Li X., Wong I.C.K. and Chan E.W., Hospitalization and Length of Stay among Patients with Non-Valvular Atrial Fibrillation Taking Dabigatran or Warfarin: A Population-Based Cohort Study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| Leung W.K., Chan E.W., Wong Y.S., Chen L., Wong O.L., Wong I.C. and Cheung M.K.S., Age of Helicobacter pylori Eradication and Subsequent Risk of Gastric Cancer Development: A Population-Based Study, Digestive Disease Week, 6-9 May 2017, Chicago, USA. 2017. |
| Li W., Huang D., Chiang C.E., Lau C.P., Tse H.F., Chan E.W., Wong I.C.K., Lip G., Chan P.H.M. and Siu D.C.W., Efficacy and Safety of Dabigatran, Rivaroxaban and Warfarin for Stroke Prevention in patients with Atrial Fibrillation: The Hong Kong Atrial Fibrillation Project, Clin Cardiol. 2017, 40(4): 222-229. |
| Li X., Chan N.S., Tam A.W., Hung F.N.I. and Chan E.W., Budget impact and cost-effectiveness analyses of direct-acting antivirals for chronic hepatitis C virus infection in Hong Kong, European Journal of Clinical Microbiology & Infectious Diseases. 2017. |
| Li X., Chan S.N., Tam A.W. and Chan E.W., Budget impact and cost-effectiveness analyses of newly available treatments for chronic hepatitis C infection in Hong Kong,, ISPOR 22nd Annual International Meeting 2017. |
| Li X., Au-Doung L.W. and Chan E.W., The Impact Of Ischemic Stroke On Atrial Fibrillation-related Healthcare Cost: A Systematic Review, ISPOR 7th Asia-Pacific Conference, 3-6th September (Poster). 2016. |
| Man K.C.K., Coghill D., Chan E.W., LAU C.Y., Hollis C., Liddle E., Banaschewski T., McCarthy S., Neubert A., Sayal K., Ip P. and Wong I.C.K., Methylphenidate and the risk of psychotic disorders and hallucinations in children and adolescents in a large health system, Translational Psychiatry. Nature Publishing Group, 2016, 6(11): e956. |
| Man K.C.K., Chan E.W., Ip P., Coghill D.R., Simonoff E., Chan P.K.L., LAU C.Y., Schuemie M.J., Sturkenboom M.C.J.M. and Wong I.C.K., Prenatal antidepressant use and risk of attention-deficit/hyperactivity disorder in offspring: population based cohort study, BMJ. 2017, j2350. |
| Man K.C.K., Li X., Chan E.W. and Wong I.C.K., The Long term use of biologics in Hong Kong., ICPE, Dublin, Ireland, 25-28th August. 2016. |
| Roughead E.E., Chan E.W., Choi N.K., Griffiths J., Lee J., Kimura T., Kubota K., Lai E.C., Man K.C.K., Nguyen T.A., Ooba N., Park B.J., Sato T., Shin J.Y., Wang T.T., Wong I.C.K., Kao Yang Y.H. and Pratt N., Proton pump inhibitors and risk of Clostridium difficile infection: a multi-country study using sequence symmetry analysis., Expert Opinion On Drug Safety. 2016, 15(12): 1589-1595. |
| Taylor D.M., Yap C., Knott J.C., Taylor S.E., Phillips G.A., Karro J., Chan E.W., Kong D.C.M. and Castle D.J., Midazolam-droperidol, droperidol or olanzapine for acute agitation: a randomised clinical trial, Ann Emerg Med. 2017, 69(3): 318-326.e1. |
| Taylor D.M.C.D., Yap C., Knott J.C., Taylor S.E., Philips G.A., Karro J., Chan E.W., Castle D.C. and Kong D.C.M., Sedating the agitated patient: a moving target? – In reply., Ann Emerg Med. 2017, 69(4): 521-523. |
| WONG Y.S., Chan E.W., Anand S., Worsley A.J. and Wong I.C.K., Managing cardiovascular risk of macrolides: systematic review and meta-analysis. , Drug Saf . 2017. |
| WONG Y.S., Wong I.C.K., CHUI S.L.C., LEE E.H.M., CHANG W.C., CHEN E.Y.H., LEUNG W.K. and Chan E.W., Neuropsychiatric Events Associated with the Use of Helicobacter Pylori Eradication Therapy Containing-Clarithromycin: Self-Controlled Case Series, 32nd ICPE, Dublin, August 26-28, 2016. |
| Yap C., Taylor D.M.C.D., Knott J.C., Taylor S.E., Phillips G.A., Karro J., Chan E.W., Kong D.C.M. and Castle D.C., Intravenous Midazolam-Droperidol Combination, Droperidol or Olanzapine Monotherapy for Methamphetamine-related Acute Agitation: A Subgroup Analysis of a Randomised Controlled Trial, Addiction. 2017. |
| Researcher : Chan WLP |
| List of Research Outputs |
| Chan L.K., Wong F.K.Y., Ganotice F.J.A., Lau W.C.S., Lam T.P., Bridges S.M., Chan N.K., Chan W.L.P., Chen H., Chen J.Y., Chu K.P.J., Ho C.C., Ho J.M.C., Chin W.Y., Harbutt D., Khoo U.S., Lam S.F., Lao L., Leung G.K.K. and Li Q., Bronze in Discipline Award (Life Sciences), in Quacquarelli Symonds (QS) Reimagine Education competition: Interprofessional Team-Based Learning for Health Professional Students, Quacquarelli Symonds. 2016. |
| Researcher : Chan WYE |
| Project Title: | Intramuscular olanzapine versus haloperidol or midazolam for the management of acute agitation in the emergency department a multicentre randomised clinical trial. |
| Investigator(s): | Chan EW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Early Career Scheme (ECS) |
| Start Date: | 01/2014 |
| Project Title: | Young adult patient experiences in clinical management of ADHD in Hong Kong |
| Investigator(s): | Chan EW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Janssen Pharmaceutica - General Award |
| Start Date: | 01/2014 |
| Project Title: | Mother’s preferences and willingness to pay for human papillomavirus vaccination for their daughters: a discrete choice experiment in Hong Kong |
| Investigator(s): | Chan EW, McGhee S, Wong CKH, Ip DKM, Chau J, Wong ICK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2014 |
| Completion Date: | 04/2017 |
| Project Title: | Oro-dispersible olanzapine (wafer) versus conventional oral haloperidol or diazepam tablets for the management of acute agitation in the Accident and Emergency Department - a multicentre randomised clinical trial. |
| Investigator(s): | Chan EW, Leung LP |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 06/2016 |
| Project Title: | 32nd International Conference on Pharmacoepidemiology & Therapeutic Risk Management; 1. #1289 - Hospitalization and Length of Stay Among Patients with Non-Valvular Atrial Fibrillation Taking Dabigatran or Warfarin: A Population-Based Cohort Study/2. #1023 - Dabigatran versus Warfarin in Patients with Non-Valvular Atrial Fibrillation: A Population-Wide Cohort Study in Chinese Patients |
| Investigator(s): | Chan EW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 08/2016 |
| Completion Date: | 08/2016 |
| Project Title: | The prescribing trends and safety of biologics in Hong Kong |
| Investigator(s): | Chan EW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | Understanding drug abuser and their healthcare pathways: Towards better management in Hong Kong |
| Investigator(s): | Chan EW, Tam AW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Beat Drugs Fund Association |
| Start Date: | 06/2017 |
| List of Research Outputs |
| Researcher : Cheung CL |
| Project Title: | Genetics and genomics of anti-thyroid drug induced agranulocytosis |
| Investigator(s): | Cheung CL, Kung AWC, Tan KCB, Sham PC, Wong ICK |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | The role of Vitamin D and bone metabolism in cardiovascular events risk, an interaction or mediation? An 11 year follow-up study |
| Investigator(s): | Cheung CL, Tan KCB, Kung AWC, Cheung BMY |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2015 |
| Project Title: | Pharmacogenomics Assessment of Serious Cutaneous Adverse drug reactions (PASCA): A retrospective study |
| Investigator(s): | Cheung CL, Chan CYJ, Sham PC, Cheung BMY, Wong ICK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | Precision Medicine of Osteoporosis Medication in Chinese (PreMOMiC): A retrospective and prospective pharmacogenomic study of denosumab |
| Investigator(s): | Cheung CL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| Completion Date: | 05/2017 |
| Project Title: | Metabolomic Study of Osteoporosis in Southern Chinese |
| Investigator(s): | Cheung CL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Early Career Scheme (ECS) |
| Start Date: | 09/2016 |
| Project Title: | Identification of susceptibility genes involved in the pathogenesis and prediction of thyrotoxic periodic paralysis |
| Investigator(s): | Cheung CL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2017 |
| Project Title: | Genetic screening service of HLA-B*38:02 in people prescribing antithyroid drug |
| Investigator(s): | Cheung CL, Tan KCB, Cheung BMY |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 03/2017 |
| Project Title: | The 44th European Calcified Tissue Society (ECTS) Congress 2017; Early anti-osteoporosis treatment and risk of cardiovascular mortality after hip fracture: A population based study |
| Investigator(s): | Cheung CL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2017 |
| Completion Date: | 05/2017 |
| List of Research Outputs |
| Cheung B.M.Y., Tam F.C.C., Cheung C.L., Chan E.Y.T., Tsui M.S.H. and Lee S.W.L., Beta-2 microglobulin level in serum is elevated in patients presenting with acute coronary syndrome., Presented at the Great Wall International Congress of Cardiology, Beijing 2016.. 2016. |
| Cheung B.M.Y., tam F., Cheung C.L., Lee S.W.L., Tsui M.S.H. and Chan E., Serum beta-2 microglobulin level is elevated in patients with acute coronary syndrome., Presented at the 13th Congress of the European Association for Clinical Pharmacology and Therapeutics, Prague, 2017.. 2017. |
| Cheung B.M.Y., Tam F.C.C., Cheung C.L., Lee S.W.L., Tsui M.S.H. and Chan E.Y.T., Serum beta-2 microglobulin level is elevated in patients with acute coronary syndrome., Presented at the 5th Seoul International Congress of Endocrinology and Metabolism 2017.. 2017. |
| Cheung C.L., Leung Y.H., Cheung B.M.Y., Nguyen U.S., Kung A.W.C. and Tan K.C.B., Optimal vitamin D status and its relationship with bone and mineral metabolism in Hong Kong Chinese., American Society for Bone and Mineral Research Annual Meeting, Atlanta, Sept 2016.. 2016. |
| Cheung C.L., Ho D.K., SING C.W., TSOI M.F., CHENG K.F., LEE K.Y., Ho Y.N. and Cheung B.M.Y., Randomized controlled trial of the effect of phytosterols-enriched low-fat milk on lipid profile in Chinese, Scientific Reports. 2017, 7: 41084. |
| Cheung C.L. and Tan K.C.B., Serum 25-hydroxyvitamin D and the risk of stroke in Hong Kong Chinese., Thromb Haemost.. 2017, 117(1): 158-163. |
| Chow K.L., Tse K.Y., Cheung C.L., Wong K.W., Cheung A.N.Y., Wong W.C., Chan A.N.H., Yuen N.W.F., Ngan H.Y.S. and Ip P.C.P., The mitosis-specific marker phosphohistone-H3 (PHH3) is an independent prognosticator in uterine smooth muscle tumours: an outcome-based study, Histopathology. United Kingdom, Wiley, 2017, 70: 746-755. |
| LAU C.Y., Chan E.W., Cheung C.L., SING C.W., Man K.C.K., Lip G.Y.H., Siu D.C.W., Lam K.Y.J., Lee C.H.A. and Wong I.C.K., Association Between Dabigatran vs Warfarin and Risk of Osteoporotic Fractures Among Patients With Nonvalvular Atrial Fibrillation, JAMA. 2017, 317: 1151. |
| LEUNG Y.H., Cheung B.M.Y., Nguyen U.S., Kung A.W.C., Tan K.C.B. and Cheung C.L., Optimal vitamin D status and its relationship with bone and mineral metabolism in Hong Kong Chinese, Bone. 2017, 97: 293-298. |
| Lee C.H.A., Chan P.H.M., Cheung C.L., Siu D.C.W., Leung Y.H., Wong T.W., Pang H.K. and Tan K.C.B., Diagnostic performance of different clinical criteria for familial hypercholesterolemia in Hong Kong Chinese patients. , 33rd Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction, Hong Kong Nov 2016.. 2016. |
| Leung Y.H., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., 25-hydroxyvitamin D and the risk of incident diabetes in Hong Kong Chinese., Presented at the 13th Congress of the European Association for Clinical Pharmacology and Therapeutics, Prague, 2017.. 2017. |
| Leung Y.H., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., 25-hydroxyvitamin D and the risk of incident diabetes in Hong Kong Chinese., Presented at the 5th Seoul International Congress of Endocrinology and Metabolism 2017.. 2017. |
| Leung Y.H., Han Y., SING C.W., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., Serum 25-hydroxyvitamin D and the risk of stroke in Hong Kong Chinese., Presented at the 20th Anniversary Scientific Meeting of the Institute of Cardiovascular Science and Medicine, 2016.. 2016. |
| Leung Y.H., Han Y., SING C.W., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., Serum 25-hydroxyvitamin D and the risk of stroke in Hong Kong Chinese, Thrombosis and Haemostasis. 2016, 117: 158-163. |
| SING C.W. and Cheung C.L., Early Anti-Osteoporosis Treatment and Risk of Mortality After Hip Fracture: A Population Based Study, WCO-IOF-ESCEO Florence 2107, March 23-26, 2017, Florence Italy. 2017. |
| SING C.W., Wong I.C.K., Cheung B.M.Y., Chan C.Y.J., Chu K.P.J. and Cheung C.L., Incidence and risk estimate of drug-induced agranulocytosis in Hong Kong Chinese. A population-based case-control study, Pharmacoepidemiology and Drug Safety. 2017, 26: 248-255. |
| TSOI M.F., Cheung T.T., Lam M.P.S. and Cheung C.L., Safety of colchicine for gout: a ten-year survey of the Hong Kong population., Presented at the 13th Congress of the European Association for Clinical Pharmacology and Therapeutics, Prague, 2017.. 2017. |
| Wong H.Y., LEE K.Y. and Cheung C.L., Metabolomics of Sarcopenia in Hong Kong Chinese, The 18th Regional Osteoporosis Conference. Hong Kong. 2017. |
| Wong H.Y., CHENG K.F., LEE K.Y. and Cheung C.L., Plenary Oral Presentation Award, Korean Endocrine Society. 2017. |
| Wong H.Y., CHENG K.F., LEE K.Y. and Cheung C.L., Precision Medicine of Denosumab Monotherapy in Osteoporotic Patients, The 5th Seoul International Congress of Endocrinology and Metabolism, SICEM 2017. |
| Researcher : Cho CH |
| Project Title: | Advances in GI Pharmacology - From Acid Secretion to Mucosal Protection Symposium Non-ulcerogenic Dose of Dexamethasone Delays Gastric Ulcer Healing in Rats |
| Investigator(s): | Cho CH |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2004 |
| Project Title: | Adrenaline and its receptor activation on colon cancer growth |
| Investigator(s): | Cho CH |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 02/2006 |
| Researcher : Chu KPJ |
| List of Research Outputs |
| Chan L.K., Wong F.K.Y., Ganotice F.J.A., Lau W.C.S., Lam T.P., Bridges S.M., Chan N.K., Chan W.L.P., Chen H., Chen J.Y., Chu K.P.J., Ho C.C., Ho J.M.C., Chin W.Y., Harbutt D., Khoo U.S., Lam S.F., Lao L., Leung G.K.K. and Li Q., Bronze in Discipline Award (Life Sciences), in Quacquarelli Symonds (QS) Reimagine Education competition: Interprofessional Team-Based Learning for Health Professional Students, Quacquarelli Symonds. 2016. |
| Chan P.T.Y. and Chu K.P.J., A Drug Use Evaluation of Amoxicillin/Clavulanate in Hospital Setting: a Focus on Prescribing Patterns, Hong Kong Pharmaceutical Journal . 2017, 24(1): 11-17. |
| Chu K.P.J., University Early Career Teaching Award, University of Hong Kong . 2016. |
| Mak C.Y. and Chu K.P.J., Antibiotic Stewardship Programme: Focusing on Ciprofloxacin , Hong Kong Pharmaceutical Journal . 2016, 23 (4): 127-131. |
| SING C.W., Wong I.C.K., Cheung B.M.Y., Chan C.Y.J., Chu K.P.J. and Cheung C.L., Incidence and risk estimate of drug-induced agranulocytosis in Hong Kong Chinese. A population-based case-control study, Pharmacoepidemiology and Drug Safety. 2017, 26: 248-255. |
| Researcher : Chui CMW |
| List of Research Outputs |
| Chung A.Y., Anand S., Wong I.C.K., Tan K.C.B., Wong C.F., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong: a multidisciplinary approach, Hong Kong Medical Journal. 2017, 23(2): 158-67. |
| Chung A.Y.S., Anand S., Wong I.C.K., Tan K.C.B., Wong F.F.C., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong – A multi-disciplinary approach., Hong Kong Med. J. . 2017, 23(2): 158-167. |
| Researcher : DETREMMERIE CMS |
| List of Research Outputs |
| DETREMMERIE C.M.S., CHEN Z., LI Z., ALKHARFY K.M., Leung S.W.S., Xu A., GAO Y. and Vanhoutte P.M.G.R., Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production, Journal of Pharmacology and Experimental Therapeutics. 2016, 358: 558-568. |
| DETREMMERIE C.M.S., Leung S.W.S., Xu A., Gao Y.S. and Vanhoutte P.M.G.R., Mechanisms of Vasodilatation 12th International Symposium. November 6-9, 2016, Rochester, Minn., USA: Abstracts, Journal of Vascular Research. 2016, 53: 1-70. |
| Researcher : Deng H |
| List of Research Outputs |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| Researcher : Dufay S |
| Project Title: | Quantitation of Dexmedetomidine in plasma for pharmacokinetic study after intranasal administration in healthy volunteers |
| Investigator(s): | Dufay S, Irwin MG, Wong ICK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2013 |
| Researcher : FENG T |
| List of Research Outputs |
| FENG T., The Role of Lactate in Macrophage Polaization and Adipose Tissue Inflammation, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| Researcher : Guo Y |
| List of Research Outputs |
| LUO D., Huang M., Guo Y., Li D., CHENG Y., Zhao J., Wang Y. and Rong J., Plant-derived triterpenoid celastrol ameliorates inflammation and metabolic dysfunctions in adipose tissues via covalent modification of ER chaperone GRP78/BiP, Keystone Symposia: Neuronal Control of Appetite, Metabolism and Weight. 9–13 May 2017, København V, Denmark. 2017. |
| Researcher : HE Y |
| List of Research Outputs |
| LAO S., HE Y., Wong I.C.K., BESAG F.M.C. and Chan E.W., Tolerability/Safety Profile of Cariprazine in Treating Psychotic Disorders/Bipolar Disorder: A Systematic Review with Meta-Analysis of RCTs , 32nd ICPE, Dublin, August 25-28, 2016. |
| Researcher : He YH |
| List of Research Outputs |
| He Y.H., Wong I.C.K., Li X., Anand S., Leung W.K., Siu D.C.W. and Chan E.W., The association between non-vitamin K antagonist oral anticoagulants and gastrointestinal bleeding: a meta-analysis of observational studies, British Journal of Clinical Pharmacology. 2016, 82(1): 285-300. |
| Researcher : Hoo RLC |
| Project Title: | The inter-relationship between A-FABF, endoplasmic reticulum stress and autophagy in the pathogenesis of obesity-induced imflammation |
| Investigator(s): | Hoo RLC, Zhang J |
| Department: | Medicine |
| Source(s) of Funding: | National Natural Science Foundation of China (NSFC) - General Program |
| Start Date: | 01/2013 |
| Project Title: | Adipocyte fatty acid binding protein (A-FABP) as a potential mediator of cardiac dysfunction and heart failure related to diabetes and obesity |
| Investigator(s): | Hoo RLC, Xia Z, Xu A |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Completion Date: | 01/2018 |
| Project Title: | Deciphering the role of lipid chaperone fatty acid binding protein 4 in the development of obesity-induced diabetic nephropathy |
| Investigator(s): | Hoo RLC, Xu A |
| Department: | Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2015 |
| Completion Date: | 03/2017 |
| Project Title: | Adipocyte fatty acid binding protein (A-FABP) is a potential therapeutic target of both alcoholic and non-alcoholic steatohepatitis |
| Investigator(s): | Hoo RLC, Xu A |
| Department: | Medicine |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | The role of adipocyte fatty acid binding protein (A-FABP) in the pathogenesis of ischemic stroke associating with obesity |
| Investigator(s): | Hoo RLC, Xu A |
| Department: | Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2016 |
| Project Title: | Adipocyte fatty acid binding protein (A-FABP) is a pathological mediator of obesity-related renal dysfunction. |
| Investigator(s): | Hoo RLC, Xu A |
| Department: | Medicine |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 06/2016 |
| Project Title: | 2016 International Congress on Obesity and Metabolic Syndrome in conjunction with the 45th Annual Scientific Meeting of KSSO; Adipocyte Fatty Acid Binding Protein (A-FABP) Modulates Adaptive Thermogenesis by Promoting Intracellular Activation of Thyroid Hormones in Brown Adipocytes |
| Investigator(s): | Hoo RLC |
| Department: | Medicine |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2016 |
| Completion Date: | 09/2016 |
| Project Title: | The role of lipid chaperone ap2 in regional adipose tissue expandability |
| Investigator(s): | Hoo RLC, Xu A |
| Department: | Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2017 |
| List of Research Outputs |
| Shu L., WU X., PAN Y., CHEONG L.Y., Xu A. and Hoo R.L.C., Adipocyte fatty acid binding protein (A-FABP) modulates adaptive thermogenesis by enhancing intracellular activation of thyroid hormones in brown adipocytes, 2016 International Congress on Obesity and Metabolic Syndrome in conjunction with the 45th Annual Scientific Meeting of KSSO . 2016. |
| Researcher : Huang M |
| List of Research Outputs |
| LUO D., Huang M., Guo Y., Li D., CHENG Y., Zhao J., Wang Y. and Rong J., Plant-derived triterpenoid celastrol ameliorates inflammation and metabolic dysfunctions in adipose tissues via covalent modification of ER chaperone GRP78/BiP, Keystone Symposia: Neuronal Control of Appetite, Metabolism and Weight. 9–13 May 2017, København V, Denmark. 2017. |
| Researcher : JIN L |
| List of Research Outputs |
| GENG L., LIAO B., JIN L., HUANG Z., Woo W.H.C., Lam K.S.L. and Xu A., Chronic exercise alleviated dietary obesity-associated metabolic dysfunction by enhancing FGF-21 sensitivity in adipose tissues., The 99th Annual Meeting of the American Endocrine Society, 1-4 April 2017, Orlando, USA. 2017. |
| Researcher : Kwok PCL |
| Project Title: | Inhalable antimicrobial peptide dry powder for tuberculosis treatment |
| Investigator(s): | Kwok PCL, Lam JKW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2014 |
| Completion Date: | 06/2017 |
| Project Title: | Aerosol performance of generic pharmaceutical combination inhalers |
| Investigator(s): | Kwok PCL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2015 |
| Completion Date: | 07/2017 |
| Project Title: | Dexmedetomidine buccal spray solution for premedication in children |
| Investigator(s): | Kwok PCL, Dufay S, Yuen VMY |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Mini Grant |
| Start Date: | 05/2015 |
| Project Title: | Transport of dexmedetomidine across the nasal mucosa |
| Investigator(s): | Kwok PCL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| Completion Date: | 07/2017 |
| Project Title: | Drug Delivery to the Lungs 27; Droplet Sizes of Electronic Cigarette Aerosols |
| Investigator(s): | Kwok PCL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 12/2016 |
| Completion Date: | 12/2016 |
| Researcher : LAO S |
| List of Research Outputs |
| LAO S., Chan E.W., Man K.C.K. and Wong I.C.K., Antipsychotic Prescription Trend in Hong Kong from 2004 to 2014, 32nd ICPE, Dublin, August 25-28, 2016. |
| LAO S., Tam A.W., Wong I.C.K., Besag F.M.C., Man K.C.K., Chui S.L.C. and Chan E.W., Prescribing trends and indications of antipsychotic medication in Hong Kong from 2004 to 2014: General and vulnerable patient groups, Pharmacoepidemiology and Drug Safety. 2017. |
| LAO S., He Y., Wong I.C.K., Besag F.M.C. and Chan E.W., Tolerability and safety profile of cariprazine in treating psychotic disorder, bipolar disorder and major depressive disorder: a systematic review with meta-analysis of randomised controlled trials., CNS Drugs. 2016, 30(11): 1043-1054. |
| LAO S., HE Y., Wong I.C.K., BESAG F.M.C. and Chan E.W., Tolerability/Safety Profile of Cariprazine in Treating Psychotic Disorders/Bipolar Disorder: A Systematic Review with Meta-Analysis of RCTs , 32nd ICPE, Dublin, August 25-28, 2016. |
| Researcher : LAU CY |
| List of Research Outputs |
| Chan E.W., LAU C.Y., Leung W.K., Michael M.T.C., Ying H., Tong S.M. and Wong I.C.K., Faculty Outstanding Research Output Award, Faculty of Medicine, The University of Hong Kong. 2016. |
| LAU C.Y., Chan E.W., Cheung C.L., SING C.W., Man K.C.K., Lip G.Y.H., Siu D.C.W., Lam K.Y.J., Lee C.H.A. and Wong I.C.K., Association Between Dabigatran vs Warfarin and Risk of Osteoporotic Fractures Among Patients With Nonvalvular Atrial Fibrillation, JAMA. 2017, 317: 1151. |
| LAU C.Y., Li X., Wong I.C.K. and Chan E.W., Bleeding-related hospital admissions and 30-day readmission with dabigatran versus warfarin in patients with non-valvular atrial fibrillation, ISPOR, Boston USA, 20-24th May (Poster) 2017. |
| LAU C.Y., Chan E.W. and Wong I.C.K., Dabigatran versus Warfarin in Patients with Non-Valvular Atrial Fibrillation: A Population-Wide Cohort Study in Chinese Patients. , ICPE, Dublin, Ireland, 25-28th August.. 2016. |
| LAU C.Y., Li X., Wong I.C.K. and Chan E.W., Hospitalization and Length of Stay among Patients with Non-Valvular Atrial Fibrillation Taking Dabigatran or Warfarin: A Population-Based Cohort Study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| Man K.C.K., Coghill D., Chan E.W., LAU C.Y., Hollis C., Liddle E., Banaschewski T., McCarthy S., Neubert A., Sayal K., Ip P. and Wong I.C.K., Methylphenidate and the risk of psychotic disorders and hallucinations in children and adolescents in a large health system, Translational Psychiatry. Nature Publishing Group, 2016, 6(11): e956. |
| Man K.C.K., Chan E.W., Ip P., Coghill D.R., Simonoff E., Chan P.K.L., LAU C.Y., Schuemie M.J., Sturkenboom M.C.J.M. and Wong I.C.K., Prenatal antidepressant use and risk of attention-deficit/hyperactivity disorder in offspring: population based cohort study, BMJ. 2017, j2350. |
| Researcher : LEE KY |
| List of Research Outputs |
| Cheung C.L., Ho D.K., SING C.W., TSOI M.F., CHENG K.F., LEE K.Y., Ho Y.N. and Cheung B.M.Y., Randomized controlled trial of the effect of phytosterols-enriched low-fat milk on lipid profile in Chinese, Scientific Reports. 2017, 7: 41084. |
| Wong H.Y., LEE K.Y. and Cheung C.L., Metabolomics of Sarcopenia in Hong Kong Chinese, The 18th Regional Osteoporosis Conference. Hong Kong. 2017. |
| Wong H.Y., CHENG K.F., LEE K.Y. and Cheung C.L., Plenary Oral Presentation Award, Korean Endocrine Society. 2017. |
| Wong H.Y., CHENG K.F., LEE K.Y. and Cheung C.L., Precision Medicine of Denosumab Monotherapy in Osteoporotic Patients, The 5th Seoul International Congress of Endocrinology and Metabolism, SICEM 2017. |
| Researcher : LEUNG YH |
| List of Research Outputs |
| LEUNG Y.H., Cheung B.M.Y., Nguyen U.S., Kung A.W.C., Tan K.C.B. and Cheung C.L., Optimal vitamin D status and its relationship with bone and mineral metabolism in Hong Kong Chinese, Bone. 2017, 97: 293-298. |
| Researcher : LI D |
| List of Research Outputs |
| LI D., CAO H., CHEN J. and Wang Y., Adiponectin-based Therapeutics in Cancer Treatment, Frontiers in Clinical Drug Research - Anti-Cancer Agents. Bentham Science, 2017, 4: 1-52. |
| Researcher : LI Z |
| List of Research Outputs |
| DETREMMERIE C.M.S., CHEN Z., LI Z., ALKHARFY K.M., Leung S.W.S., Xu A., GAO Y. and Vanhoutte P.M.G.R., Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production, Journal of Pharmacology and Experimental Therapeutics. 2016, 358: 558-568. |
| Researcher : Lam JKW |
| Project Title: | Intranasal Delivery of DNA Vaccine using Oligochitosan/PLGA Nanoparticles |
| Investigator(s): | Lam JKW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2014 |
| Completion Date: | 08/2016 |
| Project Title: | Development of a highly effective, pH responsive peptide, siRNA delivery system to the respiratory tract to combat influenza virus infections |
| Investigator(s): | Lam JKW, Poon LML |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | Formulation of carrier-free inhalable siRNA powders for the treatment of respiratory diseases |
| Investigator(s): | Lam JKW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2015 |
| Completion Date: | 06/2017 |
| Project Title: | Development of a highly efficient inhalable mucosal DNA vaccine against HIV as dry powder using pH responsive LAH peptides with nuclear localizing sequence as DNA carrier |
| Investigator(s): | Lam JKW, Chen Z, Kwok PCL, Lan Y, Chu YJ |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | National Natural Science Foundation of China (NSFC) - General Program |
| Start Date: | 01/2016 |
| Project Title: | Porous nanoparticle aerosol carriers with controllable density for pulmonary drug delivery |
| Investigator(s): | Lam JKW, Kwok PCL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2016 |
| Project Title: | Inhalable dry powder formulation of naked siRNA using spray-drying and spray freeze-drying technologies for the treatment of respiratory infections |
| Investigator(s): | Lam JKW, Kwok PCL |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2016 |
| Project Title: | Role of pulmonary surfactants on siRNA delivery to the airway |
| Investigator(s): | Lam JKW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2016 |
| Project Title: | DDL27 Drug Delivery to the Lungs 27; Synthetic KL4 peptide as new carrier of siRNA therapeutics for pulmonary delivery |
| Investigator(s): | Lam JKW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 12/2016 |
| Completion Date: | 12/2016 |
| Project Title: | Aerosolized formulation of antifungal drugs for pulmonary fungal infections |
| Investigator(s): | Lam JKW |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| List of Research Outputs |
| CHOW Y.T., Lin H.H.S. and Lam J.K.W., Optimisation of inhalable spray dried powder formulation of small nucleic acids with mannitol and leucine, Drug Delivery to the Lungs 27. 2016. |
| Casettari L., Fiagioli L., Lucarini S., Lam J.K.W., Cavanagh R. and Stolnik S., Sustainable sugar-based surfactants for innovative drug delivery systems, 6th Pharmaceutical Sciences World Congress, 21-24 May 2017, Stockholm, Sweden . 2017. |
| Lam J.K.W., Nucleic acid therapy for inhalation, Pharma+Bio Asia 2016 Conference, Kuala Lumpur, Malaysia, 28 September 2016 . 2016. |
| MAN K.W.D., Lam J.K.W. and Mason A.J., Combination of antimicrobial peptides and isoniazid/rifampicin against multidrug-resistant tuberculosis, 38th Annual Congress of the European Society of Mycobacteriology 2017, 25-28 June 2017, Sibenik, Croatia. 2017. |
| QIU Y., Lam J.K.W., Leung S.W.S. and Liang W., Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside, Molecules. 2016, 21: 1249. |
| QIU Y., CHOW Y.T. and Lam J.K.W., Synthetic KL4 peptide as new carrier of siRNA therapeutics for pulmonary delivery, Drug Delivery to the Lungs 27. 2016. |
| Sze C.W.S., WANG S., NG T.B., Lee C.K.F. and Lam J.K.W., Steroidogenic effect of Erxian decoction for relieving menopause via the p-Akt/PKB pathway in vitro and in vivo, 11th European Congress on Menopause and Andropause.. The Netherland (EMAS 2017), 2017. |
| WANG S., CHEUNG H.P., Tong Y., LU J., Ng T.B., Zhang Y., Zhang Z., Lee C.K.F., Lam J.K.W. and Sze C.W.S., Steroidogenic effect of Erxian decoction for relieving menopause via the p-Akt/PKB pathway in vitro and in vivo, Journal of Ethnopharmacology. 2017, 195: 188-195. |
| XU Y., Liang W., Qiu Y., Cespi M., Palmieri G.F., Mason A.J. and Lam J.K.W., Incorporation of a nuclear localization signal in pH responsive LAH4-L1 peptide enhances transfection and nuclear uptake of plasmid DNA, Molecular Pharmaceutics. 2016, 13: 3141-3152. |
| Researcher : Lam MPS |
| List of Research Outputs |
| TSOI M.F., Cheung T.T., Lam M.P.S. and Cheung C.L., Safety of colchicine for gout: a ten-year survey of the Hong Kong population., Presented at the 13th Congress of the European Association for Clinical Pharmacology and Therapeutics, Prague, 2017.. 2017. |
| Researcher : Leung GPH |
| Project Title: | Cloning and characterization of novel equilibrative nucleoside transporter type 4 (ENT4) |
| Investigator(s): | Leung GPH |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 03/2005 |
| Project Title: | Vascular protective effect of narirutin |
| Investigator(s): | Leung GPH |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| Project Title: | Effects of novel Rho kinase inhibitors on human nucleoside transporters |
| Investigator(s): | Leung GPH |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 03/2015 |
| Completion Date: | 02/2017 |
| Project Title: | Protective effects of Pleurotus ostreatus (Oyster mushroom) and ergothioneine against doxorubicin-induced cardiotoxicity |
| Investigator(s): | Leung GPH, Xia Z, Zhang Y, So TH |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2016 |
| Project Title: | Role of equilibrative nucleoside transporter-2 in the development of neonatal heart cells |
| Investigator(s): | Leung GPH |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2016 |
| Project Title: | Development of novel equilibrative nucleoside transporter-2 inhibitor and its application in studying the functions of equilibrative nucleoside transporter-2 in skeletal muscle |
| Investigator(s): | Leung GPH, Ballard HJ |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2016 |
| Project Title: | Role of equilibrative nucleoside transporter-4 in ischemic brain damage |
| Investigator(s): | Leung GPH |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| List of Research Outputs |
| Huang B., Peng Y., Li J., Li S., Sun Y., Wang D., Yang B., Chan J.Y.W., Yu H., Leung G.P.H., Hoi M.P.M., Zhou G.C. and Lee S.M.Y., An andrographolide derivative AGP-26b exhibiting anti-angiogenic activity in HUVECs and zebrafish via blocking the VEGFA/VEGFR2 signaling pathway, Mol. BioSyst.. 2017. |
| Li Z., Li S., Hu L., Li F., CHEUNG C., SHao W., Que Y., Leung G.P.H. and Yang C., MECHANISMS UNDERLYING ACTION OF XINMAILONG INJECTION, A TRADITIONAL CHINESE MEDICINE, IN CARDIAC FUNCTION IMPROVEMENT, African Journal of Traditional, Complementary and Alternative medicines. 2017, 14: 241-252. |
| TANG C.T.P., Yang C., Li W.S.R., Lee S.M., Hoi P.M., Chan S.W., Kwan Y.W., Tse C.M. and Leung G.P.H., Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine, European Journal of Pharmacology. 2016, 791: 544-551. |
| Tsang H.H.L., Vong C.T., Leung G.P.H., Seto S.W., Kwan Y.W., Lee S.M.Y. and Hoi M.P.M., Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa) , Evidence-Based Complementary and Alternative Medicine. 2016, 2016: 1-13. |
| Yang C., Li Z., Yang S., He Y., Dai R., Leung G.P.H., Pan S., Yang J., Yan R. and Du G., Role of the nicotinic acetylcholine receptor α3 subtype in vascular inflammation, British Journal of Pharmacology. 2016. |
| Zhou X., Choi P.S., Yang J.M., Or P.M.Y., Hoi P.M., Lee S.M., Leung G.P.H., Ngai S.M., Kong S.K., Ho H.P., Wong M.Y.M., Chan S.W., Yeung J.H.K. and Kwan Y.W., Chemical and pharmacological evaluations on the extract of Scutellaria baicalensis Georgi (Huang-Qin) prepared by various extraction methods, SpringerPlus. 2016, 5. |
| Zhou X., Cui G., Tseng H.H.L., Lee S.M.Y., Leung G.P.H., Chan S.W., Kwan Y.W. and Hoi M.P.M., Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine, Evidence-Based Complementary and Alternative Medicine. 2016, 2016: 1-12. |
| Researcher : Leung SWS |
| Project Title: | Therapeutic potential of herbal flavonoids in the management of chronic obstructive pulmonary disease |
| Investigator(s): | Leung SWS, Mak JCW, Man RYK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 11/2013 |
| Completion Date: | 07/2017 |
| Project Title: | Vasoconstrictor signals in hypoxia: role of soluble guanylyl cyclase |
| Investigator(s): | Leung SWS, Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | Effect s of different components of the Chinese medicine, Astragali Radix (Huangqi), on angiogenic and inflammatory responses of endothelial cells to atherogenic lipoproteins |
| Investigator(s): | Leung SWS |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2015 |
| Completion Date: | 05/2017 |
| Project Title: | Vascular effect of thymoquinone, a natural product used in humans as a folk medicine |
| Investigator(s): | Leung SWS, Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| Project Title: | Mechanisms of Vasodilatation: 12th International Symposium; Modulation by fish oil diet of gender differences in the relaxation to adenosine diphosphate in porcine coronary arteries |
| Investigator(s): | Leung SWS |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2016 |
| Completion Date: | 11/2016 |
| Project Title: | MicroRNA-17-3p curtails endothelial dysfunction and vascular inflammation |
| Investigator(s): | Leung SWS, Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | Effects of microRNA-17-3p upregulation on vascular inflammation and endothelial dysfunction caused by the human immunodeficiency virus proteins |
| Investigator(s): | Leung SWS, Lam JKW, Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 06/2017 |
| List of Research Outputs |
| CHEN H. and Leung S.W.S., AMPK Activator Inhibits EDH-like Relaxations in Superior Mesenteric Arteries of Rats, 12th International Symposium on Healthy Aging, 11-12 March 2017, Hong Kong. 2017. |
| DETREMMERIE C.M.S., CHEN Z., LI Z., ALKHARFY K.M., Leung S.W.S., Xu A., GAO Y. and Vanhoutte P.M.G.R., Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production, Journal of Pharmacology and Experimental Therapeutics. 2016, 358: 558-568. |
| DETREMMERIE C.M.S., Leung S.W.S., Xu A., Gao Y.S. and Vanhoutte P.M.G.R., Mechanisms of Vasodilatation 12th International Symposium. November 6-9, 2016, Rochester, Minn., USA: Abstracts, Journal of Vascular Research. 2016, 53: 1-70. |
| Jin J., Tang Q., Li Z., Zhao Z., Zhang Z., Lu L., Zhu T., Vanhoutte P.M.G.R., Leung S.W.S., Tu R. and Shi Y., Prostaglandin E2 regulates renal function in C57/BL6 mouse with 5/6 nephrectomy, Life Sci. 2017, 174: 68-76. |
| Leung S.W.S. and Vanhoutte P.M.G.R., Endothelium-dependent hyperpolarization: age, gender and blood pressure, do they matter?, Acta Physiol (Oxf). 2017, 219: 108-123. |
| QIU Y., Lam J.K.W., Leung S.W.S. and Liang W., Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside, Molecules. 2016, 21: 1249. |
| ZHANG P., Mak J.C.W., Man R.Y.K. and Leung S.W.S., Effects of genistein on inflammatory responses in cigarette smoke-exposed rats, Pharmacology 2016, The Queen Elizabeth II Conference Centre, London, 13-15 December, 2016. |
| Researcher : Li WSR |
| List of Research Outputs |
| TANG C.T.P., Yang C., Li W.S.R., Lee S.M., Hoi P.M., Chan S.W., Kwan Y.W., Tse C.M. and Leung G.P.H., Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine, European Journal of Pharmacology. 2016, 791: 544-551. |
| Researcher : Li X |
| Project Title: | ISPOR 22nd International Annual Meeting; BUDGET IMPACT AND COST-EFFECTIVENESS ANALYSES OF NEWLY AVAILABLE TREATMENTS FOR CHRONIC HEPATITIS C INFECTION IN HONG KONG |
| Investigator(s): | Li X |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2017 |
| Completion Date: | 05/2017 |
| List of Research Outputs |
| He Y.H., Wong I.C.K., Li X., Anand S., Leung W.K., Siu D.C.W. and Chan E.W., The association between non-vitamin K antagonist oral anticoagulants and gastrointestinal bleeding: a meta-analysis of observational studies, British Journal of Clinical Pharmacology. 2016, 82(1): 285-300. |
| LAU C.Y., Li X., Wong I.C.K. and Chan E.W., Bleeding-related hospital admissions and 30-day readmission with dabigatran versus warfarin in patients with non-valvular atrial fibrillation, ISPOR, Boston USA, 20-24th May (Poster) 2017. |
| LAU C.Y., Li X., Wong I.C.K. and Chan E.W., Hospitalization and Length of Stay among Patients with Non-Valvular Atrial Fibrillation Taking Dabigatran or Warfarin: A Population-Based Cohort Study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| Li X., Chan N.S., Tam A.W., Hung F.N.I. and Chan E.W., Budget impact and cost-effectiveness analyses of direct-acting antivirals for chronic hepatitis C virus infection in Hong Kong, European Journal of Clinical Microbiology & Infectious Diseases. 2017. |
| Li X., Chan S.N., Tam A.W. and Chan E.W., Budget impact and cost-effectiveness analyses of newly available treatments for chronic hepatitis C infection in Hong Kong,, ISPOR 22nd Annual International Meeting 2017. |
| Li X., Au-Doung L.W. and Chan E.W., The Impact Of Ischemic Stroke On Atrial Fibrillation-related Healthcare Cost: A Systematic Review, ISPOR 7th Asia-Pacific Conference, 3-6th September (Poster). 2016. |
| Man K.C.K., Li X., Chan E.W. and Wong I.C.K., The Long term use of biologics in Hong Kong., ICPE, Dublin, Ireland, 25-28th August. 2016. |
| Researcher : Liang W |
| List of Research Outputs |
| QIU Y., Lam J.K.W., Leung S.W.S. and Liang W., Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside, Molecules. 2016, 21: 1249. |
| XU Y., Liang W., Qiu Y., Cespi M., Palmieri G.F., Mason A.J. and Lam J.K.W., Incorporation of a nuclear localization signal in pH responsive LAH4-L1 peptide enhances transfection and nuclear uptake of plasmid DNA, Molecular Pharmaceutics. 2016, 13: 3141-3152. |
| Researcher : Lui WYV |
| Project Title: | A Precision Therapeutic Tool for Head and Neck Cancer (HNC) |
| Investigator(s): | Lui WYV |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Translational and Applied Research |
| Start Date: | 03/2015 |
| Project Title: | HKU Overseas Fellowship Awards 2015-16 |
| Investigator(s): | Lui WYV |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | HKU Overseas Fellowship Awards |
| Start Date: | 06/2015 |
| Researcher : Luo C |
| List of Research Outputs |
| Song E., Jahng J.W., Chong L.P., Sung H.K., Han M., Luo C., Boo S., Hinz B., Cooper M.A., Wang Y., Wu D., Robertson A.A., Berger T., Mak T.W., George I., Schulze P.C. and Sweeney G., Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge, Am J Transl Res.. 2017, 9(6): 2723-2735. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu C. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31: Suppl 998.10. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu A. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31. |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| Researcher : MAN KWD |
| List of Research Outputs |
| MAN K.W.D., Lam J.K.W. and Mason A.J., Combination of antimicrobial peptides and isoniazid/rifampicin against multidrug-resistant tuberculosis, 38th Annual Congress of the European Society of Mycobacteriology 2017, 25-28 June 2017, Sibenik, Croatia. 2017. |
| Researcher : MAN WC |
| List of Research Outputs |
| MAN W.C. and Wang Y., Age-associated Arterial Remodelling and Cardiovascular Diseases, Abnormalities of Vascular System. 2017. |
| MAN W.C., Overexpression of SIRT1 Selectively in Vascular Endothelium Maintains the Circadian Rhythm of blood Pressure in PER2-deficient Mice, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| Man W.C. and Wang Y., Age-associated arterial remodeling, Abnormalities of Vascular System. 2017, http://openaccessebooks.com/vascular-system.html. |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| Researcher : Man KCK |
| List of Research Outputs |
| LAO S., Chan E.W., Man K.C.K. and Wong I.C.K., Antipsychotic Prescription Trend in Hong Kong from 2004 to 2014, 32nd ICPE, Dublin, August 25-28, 2016. |
| Man K.C.K., Li X., Chan E.W. and Wong I.C.K., The Long term use of biologics in Hong Kong., ICPE, Dublin, Ireland, 25-28th August. 2016. |
| Researcher : Man RYK |
| List of Research Outputs |
| ZHANG P., Mak J.C.W., Man R.Y.K. and Leung S.W.S., Effects of genistein on inflammatory responses in cigarette smoke-exposed rats, Pharmacology 2016, The Queen Elizabeth II Conference Centre, London, 13-15 December, 2016. |
| Researcher : Man WC |
| List of Research Outputs |
| MAN W.C. and Wang Y., Age-associated Arterial Remodelling and Cardiovascular Diseases, Abnormalities of Vascular System. 2017. |
| MAN W.C., Overexpression of SIRT1 Selectively in Vascular Endothelium Maintains the Circadian Rhythm of blood Pressure in PER2-deficient Mice, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| Man W.C. and Wang Y., Age-associated arterial remodeling, Abnormalities of Vascular System. 2017, http://openaccessebooks.com/vascular-system.html. |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| Researcher : QIU Y |
| List of Research Outputs |
| QIU Y., Lam J.K.W., Leung S.W.S. and Liang W., Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside, Molecules. 2016, 21: 1249. |
| QIU Y., CHOW Y.T. and Lam J.K.W., Synthetic KL4 peptide as new carrier of siRNA therapeutics for pulmonary delivery, Drug Delivery to the Lungs 27. 2016. |
| XU Y., Liang W., Qiu Y., Cespi M., Palmieri G.F., Mason A.J. and Lam J.K.W., Incorporation of a nuclear localization signal in pH responsive LAH4-L1 peptide enhances transfection and nuclear uptake of plasmid DNA, Molecular Pharmaceutics. 2016, 13: 3141-3152. |
| Researcher : Qiu Y |
| List of Research Outputs |
| QIU Y., Lam J.K.W., Leung S.W.S. and Liang W., Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside, Molecules. 2016, 21: 1249. |
| QIU Y., CHOW Y.T. and Lam J.K.W., Synthetic KL4 peptide as new carrier of siRNA therapeutics for pulmonary delivery, Drug Delivery to the Lungs 27. 2016. |
| XU Y., Liang W., Qiu Y., Cespi M., Palmieri G.F., Mason A.J. and Lam J.K.W., Incorporation of a nuclear localization signal in pH responsive LAH4-L1 peptide enhances transfection and nuclear uptake of plasmid DNA, Molecular Pharmaceutics. 2016, 13: 3141-3152. |
| Researcher : SING CW |
| List of Research Outputs |
| Botzenhardt S., Wong I.C.K., Chan E.W., SING C.W. and Neubert A., Safety profiles of iron chelators in young patients with haemoglobinopathies, Eur J Haematol . 2017, 98(3): 198-217. |
| Cheung C.L., Ho D.K., SING C.W., TSOI M.F., CHENG K.F., LEE K.Y., Ho Y.N. and Cheung B.M.Y., Randomized controlled trial of the effect of phytosterols-enriched low-fat milk on lipid profile in Chinese, Scientific Reports. 2017, 7: 41084. |
| LAU C.Y., Chan E.W., Cheung C.L., SING C.W., Man K.C.K., Lip G.Y.H., Siu D.C.W., Lam K.Y.J., Lee C.H.A. and Wong I.C.K., Association Between Dabigatran vs Warfarin and Risk of Osteoporotic Fractures Among Patients With Nonvalvular Atrial Fibrillation, JAMA. 2017, 317: 1151. |
| Leung Y.H., Han Y., SING C.W., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., Serum 25-hydroxyvitamin D and the risk of stroke in Hong Kong Chinese., Presented at the 20th Anniversary Scientific Meeting of the Institute of Cardiovascular Science and Medicine, 2016.. 2016. |
| Leung Y.H., Han Y., SING C.W., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., Serum 25-hydroxyvitamin D and the risk of stroke in Hong Kong Chinese, Thrombosis and Haemostasis. 2016, 117: 158-163. |
| SING C.W. and Cheung C.L., Early Anti-Osteoporosis Treatment and Risk of Mortality After Hip Fracture: A Population Based Study, WCO-IOF-ESCEO Florence 2107, March 23-26, 2017, Florence Italy. 2017. |
| SING C.W., Wong I.C.K., Cheung B.M.Y., Chan C.Y.J., Chu K.P.J. and Cheung C.L., Incidence and risk estimate of drug-induced agranulocytosis in Hong Kong Chinese. A population-based case-control study, Pharmacoepidemiology and Drug Safety. 2017, 26: 248-255. |
| Researcher : SONG E |
| List of Research Outputs |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| Researcher : Sun WY |
| Project Title: | Experimental Biology Meeting 2017; Role of lipocalin-2 in dietary or aldosterone-induced renal damages |
| Investigator(s): | Sun WY |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 04/2017 |
| Completion Date: | 04/2017 |
| List of Research Outputs |
| Sun W.Y. and Wang Y., Calorie restriction mimetics from functional foods: impact on promoting healthy lifespan, Nutrition and Functional Foods for Healthy Aging, publisher. Elesvier, 2017. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu C. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31: Suppl 998.10. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu A. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31. |
| Researcher : TANG CTP |
| List of Research Outputs |
| TANG C.T.P., Yang C., Li W.S.R., Lee S.M., Hoi P.M., Chan S.W., Kwan Y.W., Tse C.M. and Leung G.P.H., Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine, European Journal of Pharmacology. 2016, 791: 544-551. |
| Researcher : Tam AW |
| List of Research Outputs |
| LAO S., Tam A.W., Wong I.C.K., Besag F.M.C., Man K.C.K., Chui S.L.C. and Chan E.W., Prescribing trends and indications of antipsychotic medication in Hong Kong from 2004 to 2014: General and vulnerable patient groups, Pharmacoepidemiology and Drug Safety. 2017. |
| Li X., Chan N.S., Tam A.W., Hung F.N.I. and Chan E.W., Budget impact and cost-effectiveness analyses of direct-acting antivirals for chronic hepatitis C virus infection in Hong Kong, European Journal of Clinical Microbiology & Infectious Diseases. 2017. |
| Li X., Chan S.N., Tam A.W. and Chan E.W., Budget impact and cost-effectiveness analyses of newly available treatments for chronic hepatitis C infection in Hong Kong,, ISPOR 22nd Annual International Meeting 2017. |
| Researcher : Tang EHC |
| Project Title: | Telomere-independent Rap1 contributes to inflammation during atherosclerosis |
| Investigator(s): | Tang EHC, Man RYK, Leung SWS |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | National Natural Science Foundation of China (NSFC) - General Program |
| Start Date: | 01/2013 |
| Project Title: | Regulation of triglyceride metabolism by prostaglandin E receptor subtype 4 |
| Investigator(s): | Tang EHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2013 |
| Project Title: | Rap1 aggravates the development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice. |
| Investigator(s): | Tang EHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2014 |
| Project Title: | Enhancement of the fat-burning capacity of white and brown adipose tissue by activation of prostaglandin E receptor subtype 4 |
| Investigator(s): | Tang EHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Early Career Scheme (ECS) |
| Start Date: | 12/2014 |
| Project Title: | Unexpected role of the telomere-associated protein Rap1 in protecting against endothelial dysfunction |
| Investigator(s): | Tang EHC, Vanhoutte PMGR, Xu A |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2017 |
| List of Research Outputs |
| Cai Y., PANG L., Tang E.H.C., Irwin M.G. and Xia Z., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis viaAkt-dependent enhancentment of iNOS expression, 14th Annual Meeting of the Society for Heart and Vascular Metabolism. 2016. |
| PANG L., Cai Y., Tang E.H.C., YAN D., Li H., IRWIN M.G., MA H., Xia Z. and RAMOJI K., COX-2 inhibition protects against hypoxia/reoxygenation-induced cardiomyocyte apoptosis via Akt-dependent enhancentment of iNOS expression, Oxidative Medicine and Cellular Longevity. 2016. |
| YING F. and Tang E.H.C., Deficiency of Prostaglandin E Receptor Subtype 4 (EP4) Favored Multilocular Fat Cell Formation and Increased Mitochondrial Biogenesis through the AMPK-FSP27 Axis, 12th International Symposium on Healthy Aging, 11-12 March 2017, Hong Kong. 2017. |
| YING F., Cai Y., Wong H.K., Lee T. and Tang E.H.C., Disturbed cholesterol homeostasis in prostaglandin E receptor 4 knockout mice model, The 6th ICCR Congress on Chronic societal Cardiometabolic Diseases. 2017. |
| YING F., Cai Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 (EP4) regulates lipid droplet size and mitochondrial activity via FSP27 in white adipose tissue, Metabolic Diseases; Breakthrough Discoveries in Diabetes & Obesity, Novotel Melbourne St Kilda, 1-2 December 2016. |
| YING F., Cai Y., CAI Y., Wang Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 regulates lipid droplet size and mitochondrial activity in murine subcutaneous white adipose tissue, The FASEB Journal. 2017, 331: 4023-4036. |
| YING F., Cai Y. and Tang E.H.C., Prostaglandin receptor subtype 4 (EP4) deficiency enhanced multilocular fat cell formation and mitochondrial biogenesis and facilated wat remodeling, The 6th ICCR Congress on Chronic Societal Cardiometabolic Diseases, May 15-17, 2017, Quebec Canada. 2017. |
| Researcher : Tang HC |
| Project Title: | Telomere-independent Rap1 contributes to inflammation during atherosclerosis |
| Investigator(s): | Tang EHC, Man RYK, Leung SWS |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | National Natural Science Foundation of China (NSFC) - General Program |
| Start Date: | 01/2013 |
| Project Title: | Regulation of triglyceride metabolism by prostaglandin E receptor subtype 4 |
| Investigator(s): | Tang EHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2013 |
| Project Title: | Rap1 aggravates the development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice. |
| Investigator(s): | Tang EHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2014 |
| Project Title: | Enhancement of the fat-burning capacity of white and brown adipose tissue by activation of prostaglandin E receptor subtype 4 |
| Investigator(s): | Tang EHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Early Career Scheme (ECS) |
| Start Date: | 12/2014 |
| Project Title: | Unexpected role of the telomere-associated protein Rap1 in protecting against endothelial dysfunction |
| Investigator(s): | Tang EHC, Vanhoutte PMGR, Xu A |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2017 |
| List of Research Outputs |
| Researcher : Tom WM |
| Project Title: | VII World Conference on Clinical Pharmacology and Therapeutics 4th Congress of the European Association for Clinical Pharmacology and Therapeutics Antidotal Mechanisms of Hydroxyacetone and Dihydroxyacetone in the Treatment of Acute Acetonitrile Poisoning |
| Investigator(s): | Tom WM |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2000 |
| Researcher : Tong HYH |
| List of Research Outputs |
| Anand S., Tong H.Y.H., Besag F.M.C., Chan E.W., Cortese S. and Wong I.C.K., Safety, Tolerability And Efficacy Of Drugs For Treating Behavioural Insomnia In Children With Attention-deficit/hyperactivity Disorder: A Systematic Review With Methodological Quality Assessment. , Pediatr Drugs . 2017, 19(3): 235-250. |
| Researcher : Vanhoutte P.M.G. |
| Project Title: | Annual Summer School in Danish Cardiovascular Research Academy Veins in health and disease |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2007 |
| Project Title: | Visiting Research Professors Scheme 2009-10 |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Visiting Research Professors Scheme |
| Start Date: | 09/2009 |
| Project Title: | A Study of the Relative Significance of Nitric Oxide Synthase vs NADPH oxidase in Endothelial Senescence |
| Investigator(s): | Vanhoutte PMGR, Wang Y |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2009 |
| Project Title: | Human Prostacyclin Receptors and Endothelial Dysfunction |
| Investigator(s): | Vanhoutte PMGR, Xu A, Wang Y, Leung SWS |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2016 |
| List of Research Outputs |
| Researcher : Vanhoutte PMGR |
| Project Title: | Annual Summer School in Danish Cardiovascular Research Academy Veins in health and disease |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2007 |
| Project Title: | Visiting Research Professors Scheme 2009-10 |
| Investigator(s): | Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Visiting Research Professors Scheme |
| Start Date: | 09/2009 |
| Project Title: | A Study of the Relative Significance of Nitric Oxide Synthase vs NADPH oxidase in Endothelial Senescence |
| Investigator(s): | Vanhoutte PMGR, Wang Y |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2009 |
| Project Title: | Human Prostacyclin Receptors and Endothelial Dysfunction |
| Investigator(s): | Vanhoutte PMGR, Xu A, Wang Y, Leung SWS |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2016 |
| List of Research Outputs |
| Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice, Acta Pharmacologica Sinica. 2017, 38: 498-512. |
| DETREMMERIE C.M.S., CHEN Z., LI Z., ALKHARFY K.M., Leung S.W.S., Xu A., GAO Y. and Vanhoutte P.M.G.R., Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production, Journal of Pharmacology and Experimental Therapeutics. 2016, 358: 558-568. |
| DETREMMERIE C.M.S., Leung S.W.S., Xu A., Gao Y.S. and Vanhoutte P.M.G.R., Mechanisms of Vasodilatation 12th International Symposium. November 6-9, 2016, Rochester, Minn., USA: Abstracts, Journal of Vascular Research. 2016, 53: 1-70. |
| Feletou M. and Vanhoutte P.M.G.R., Endothelium-dependent hyperpolarizations: Quo vadis?, Acta Physiologica. 2017, 219: 100-107. |
| Jin J., Tang Q., Li Z., Zhao Z., Zhang Z., Lu L., Zhu T., Vanhoutte P.M.G.R., Leung S.W.S., Tu R. and Shi Y., Prostaglandin E2 regulates renal function in C57/BL6 mouse with 5/6 nephrectomy, Life Sci. 2017, 174: 68-76. |
| Leung S.W.S. and Vanhoutte P.M.G.R., Endothelium-dependent hyperpolarization: age, gender and blood pressure, do they matter?, Acta Physiol (Oxf). 2017, 219: 108-123. |
| Miller V.M., Webb R.C. and Vanhoutte P.M.G.R., 12th International Symposium for Mechanisms of Vasodilatation: Celebrating the 30th Anniversary of the Announcement of NO as a Vasodilator Molecule, J Cardiovasc Pharmacol. 2017, 69(5): 245-247. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu C. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31: Suppl 998.10. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu A. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31. |
| Vanhoutte P.M.G.R., An old wheel gets a new CART …, European Heart Journal. 2016, 38: ehw508. |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| Zhou M., Bao Y., LI H., PAN Y., SHU L., Xia Z., Wu D., Vanhoutte P.M.G.R., Xu A., Jia W. and Hoo R.L.C., Deficiency of adipocyte fatty-acid-binding protein alleviates myocardial ischaemia/reperfusion injury and diabetes-induced cardiac dysfunction., Clinical Science. 2016. |
| Researcher : Verhoeft KR |
| List of Research Outputs |
| Li Y.Y., Chung G.T., Lui W.Y.V., To K.F., Ma B.B., Chow C., Woo J.K., Yip K.Y., Seo J., Hui E.P., Mak M.K., Rusan M., Chau N.G., Or Y.Y., Law M.H., Law P.P., Liu Z.W., NGAN H.L., Hau P.M., Verhoeft K.R., Poon P.H., Yoo S.K., Shin J.Y., Lee S.D., Lun S.W., Jia L.J., Chan A.W., Chan J.Y., Lai P.B., Fung C.Y., Hung S.T., Wang L., Chang A.M., Chiosea S.I., Hedberg M.L., Tsao G.S.W., van Hasselt A.C., Chan A.T., Grandis J.R., Nature Communications P.S. and Lo K.W., Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations, Nature Communications. 2017. |
| Researcher : WANG Y |
| List of Research Outputs |
| Gong Q., Hu Z., Zhang F., Cui A., Chen X., Jiang H., Gao J., Chen X., Han Y., Liang Q., Ye D., Shi L., Chin Y.E., Wang Y., Xiao H., Guo F., Liu Y., Zang M., Xu A. and Li Y., Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice, Hepatology. 2016, 64: 425-438. |
| Hui X., Gu P., Zhang J., Wang Y. and Xu A., 2016 Research Output Award, The University of Hong Kong. 2016. |
| Hui X., Gao Y., Wang Y. and Xu A., Adipocyte SIRT1 controls systemic insulin sensitivity by modulating macrophages in adipose tissue, EMBO reports. 2017, 18: 645-657. |
| LI D., CAO H., CHEN J. and Wang Y., Adiponectin-based Therapeutics in Cancer Treatment, Frontiers in Clinical Drug Research - Anti-Cancer Agents. Bentham Science, 2017, 4: 1-52. |
| LUO D., Huang M., Guo Y., Li D., CHENG Y., Zhao J., Wang Y. and Rong J., Plant-derived triterpenoid celastrol ameliorates inflammation and metabolic dysfunctions in adipose tissues via covalent modification of ER chaperone GRP78/BiP, Keystone Symposia: Neuronal Control of Appetite, Metabolism and Weight. 9–13 May 2017, København V, Denmark. 2017. |
| MAN W.C. and Wang Y., Age-associated Arterial Remodelling and Cardiovascular Diseases, Abnormalities of Vascular System. 2017. |
| Man W.C. and Wang Y., Age-associated arterial remodeling, Abnormalities of Vascular System. 2017, http://openaccessebooks.com/vascular-system.html. |
| Mao L., Nie B., Nie T., Hui X., Gao X., Lin X., Liu X., Xu Y., Tang X., Yuan R., Li K., Li P., Ding K., Wang Y., Xu A., Fei J., Han W., Liu P., Madsen L., Kristansen K., Zhou Z., Deng S. and Wu D., Visualization and Quantification of Browning Using a Ucp1 -2A-Luciferase Knock-in Mouse Model , Diabetes. 2017, 66: 407-417. |
| Song E., Jahng J.W., Chong L.P., Sung H.K., Han M., Luo C., Boo S., Hinz B., Cooper M.A., Wang Y., Wu D., Robertson A.A., Berger T., Mak T.W., George I., Schulze P.C. and Sweeney G., Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge, Am J Transl Res.. 2017, 9(6): 2723-2735. |
| Sun W.Y. and Wang Y., Calorie restriction mimetics from functional foods: impact on promoting healthy lifespan, Nutrition and Functional Foods for Healthy Aging, publisher. Elesvier, 2017. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu C. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31: Suppl 998.10. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu A. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31. |
| WANG Y., TSE M.A., LIU Y., Zhu C.F., Liang Q. and Xu A., High Intensity Exercise: A Multi-beneficial Exercise Modality to Promote Browning of White Adipose Tissue, Reduce Fat Accumulation and Control Metabolic Disease, 10th International Conference on Strength Training, Kyoto, Japan, November 30-December 2, 2016. |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| YING F., Cai Y., CAI Y., Wang Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 regulates lipid droplet size and mitochondrial activity in murine subcutaneous white adipose tissue, The FASEB Journal. 2017, 331: 4023-4036. |
| Researcher : WONG YS |
| List of Research Outputs |
| CHUI S.L.C., WONG Y.S., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Potential association between the use of oral fluoroquinolones and acute neuropsychiatric disorders in Hong Kong: a self-controlled case series study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| CHUI S.L.C., Wong I.C.K., WONG Y.S., LEE E.H.M., CHANG W.C., CHEN E.Y.H. and Chan E.W., The Association Between the Use of Oral Fluoroquinolones and Neuropsychiatric Events: A Self-Controlled Case Series Study, 32nd ICPE, Dublin, August 25-28, 2016. |
| Leung W.K., Chan E.W., Wong Y.S., Chen L., Wong O.L., Wong I.C. and Cheung M.K.S., Age of Helicobacter pylori Eradication and Subsequent Risk of Gastric Cancer Development: A Population-Based Study, Digestive Disease Week, 6-9 May 2017, Chicago, USA. 2017. |
| WONG Y.S., Chan E.W., Anand S., Worsley A.J. and Wong I.C.K., Managing cardiovascular risk of macrolides: systematic review and meta-analysis. , Drug Saf . 2017. |
| WONG Y.S., Wong I.C.K., CHUI S.L.C., LEE E.H.M., CHANG W.C., CHEN E.Y.H., LEUNG W.K. and Chan E.W., Neuropsychiatric Events Associated with the Use of Helicobacter Pylori Eradication Therapy Containing-Clarithromycin: Self-Controlled Case Series, 32nd ICPE, Dublin, August 26-28, 2016. |
| Researcher : Wang Y |
| Project Title: | Outstanding Young Researcher Award 2009-10 |
| Investigator(s): | Wang Y |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Outstanding Young Researcher Award |
| Start Date: | 12/2010 |
| Project Title: | HERC2 as a regulator of endothelial senescence by modulating SIRT1/LKB1 signaling axis |
| Investigator(s): | Wang Y, Tse HF |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Completion Date: | 12/2016 |
| Project Title: | Molecular dissection of the pathogenic adipose-vascular signaling axis associated with obesity - focusing on polyamination and deamidation of lipocalin-2 |
| Investigator(s): | Wang Y, Yuen KY |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | Role of Endothelial SIRT1 in the Prevention of Vascular Ageing - focusing on arterial remodeling and circadian rhythmicity |
| Investigator(s): | Wang Y, Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 09/2016 |
| Project Title: | Timely resetting mitochondrial function by SIRT1 in adipose tissue determines the pace of metabolic ageing in mice |
| Investigator(s): | Wang Y |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2017 |
| Project Title: | Role of lipocalin-2 in adipose tissue expansion, phenotypic switching and fibrotic damages during the development of cardiometabolic syndrome |
| Investigator(s): | Wang Y, Sun WY |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| List of Research Outputs |
| Gong Q., Hu Z., Zhang F., Cui A., Chen X., Jiang H., Gao J., Chen X., Han Y., Liang Q., Ye D., Shi L., Chin Y.E., Wang Y., Xiao H., Guo F., Liu Y., Zang M., Xu A. and Li Y., Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice, Hepatology. 2016, 64: 425-438. |
| Hui X., Gu P., Zhang J., Wang Y. and Xu A., 2016 Research Output Award, The University of Hong Kong. 2016. |
| Hui X., Gao Y., Wang Y. and Xu A., Adipocyte SIRT1 controls systemic insulin sensitivity by modulating macrophages in adipose tissue, EMBO reports. 2017, 18: 645-657. |
| LI D., CAO H., CHEN J. and Wang Y., Adiponectin-based Therapeutics in Cancer Treatment, Frontiers in Clinical Drug Research - Anti-Cancer Agents. Bentham Science, 2017, 4: 1-52. |
| LUO D., Huang M., Guo Y., Li D., CHENG Y., Zhao J., Wang Y. and Rong J., Plant-derived triterpenoid celastrol ameliorates inflammation and metabolic dysfunctions in adipose tissues via covalent modification of ER chaperone GRP78/BiP, Keystone Symposia: Neuronal Control of Appetite, Metabolism and Weight. 9–13 May 2017, København V, Denmark. 2017. |
| MAN W.C. and Wang Y., Age-associated Arterial Remodelling and Cardiovascular Diseases, Abnormalities of Vascular System. 2017. |
| Man W.C. and Wang Y., Age-associated arterial remodeling, Abnormalities of Vascular System. 2017, http://openaccessebooks.com/vascular-system.html. |
| Mao L., Nie B., Nie T., Hui X., Gao X., Lin X., Liu X., Xu Y., Tang X., Yuan R., Li K., Li P., Ding K., Wang Y., Xu A., Fei J., Han W., Liu P., Madsen L., Kristansen K., Zhou Z., Deng S. and Wu D., Visualization and Quantification of Browning Using a Ucp1 -2A-Luciferase Knock-in Mouse Model , Diabetes. 2017, 66: 407-417. |
| Song E., Jahng J.W., Chong L.P., Sung H.K., Han M., Luo C., Boo S., Hinz B., Cooper M.A., Wang Y., Wu D., Robertson A.A., Berger T., Mak T.W., George I., Schulze P.C. and Sweeney G., Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge, Am J Transl Res.. 2017, 9(6): 2723-2735. |
| Sun W.Y. and Wang Y., Calorie restriction mimetics from functional foods: impact on promoting healthy lifespan, Nutrition and Functional Foods for Healthy Aging, publisher. Elesvier, 2017. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu C. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31: Suppl 998.10. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu A. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31. |
| WANG Y., TSE M.A., LIU Y., Zhu C.F., Liang Q. and Xu A., High Intensity Exercise: A Multi-beneficial Exercise Modality to Promote Browning of White Adipose Tissue, Reduce Fat Accumulation and Control Metabolic Disease, 10th International Conference on Strength Training, Kyoto, Japan, November 30-December 2, 2016. |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| YING F., Cai Y., CAI Y., Wang Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 regulates lipid droplet size and mitochondrial activity in murine subcutaneous white adipose tissue, The FASEB Journal. 2017, 331: 4023-4036. |
| Researcher : Wang Y. |
| Project Title: | Outstanding Young Researcher Award 2009-10 |
| Investigator(s): | Wang Y |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Outstanding Young Researcher Award |
| Start Date: | 12/2010 |
| Project Title: | HERC2 as a regulator of endothelial senescence by modulating SIRT1/LKB1 signaling axis |
| Investigator(s): | Wang Y, Tse HF |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Completion Date: | 12/2016 |
| Project Title: | Molecular dissection of the pathogenic adipose-vascular signaling axis associated with obesity - focusing on polyamination and deamidation of lipocalin-2 |
| Investigator(s): | Wang Y, Yuen KY |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | Role of Endothelial SIRT1 in the Prevention of Vascular Ageing - focusing on arterial remodeling and circadian rhythmicity |
| Investigator(s): | Wang Y, Vanhoutte PMGR |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 09/2016 |
| Project Title: | Timely resetting mitochondrial function by SIRT1 in adipose tissue determines the pace of metabolic ageing in mice |
| Investigator(s): | Wang Y |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2017 |
| Project Title: | Role of lipocalin-2 in adipose tissue expansion, phenotypic switching and fibrotic damages during the development of cardiometabolic syndrome |
| Investigator(s): | Wang Y, Sun WY |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| List of Research Outputs |
| Researcher : Wong FFC |
| List of Research Outputs |
| Chung A.Y.S., Anand S., Wong I.C.K., Tan K.C.B., Wong F.F.C., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong – A multi-disciplinary approach., Hong Kong Med. J. . 2017, 23(2): 158-167. |
| Researcher : Wong HK |
| List of Research Outputs |
| YING F., Cai Y., Wong H.K., Lee T. and Tang E.H.C., Disturbed cholesterol homeostasis in prostaglandin E receptor 4 knockout mice model, The 6th ICCR Congress on Chronic societal Cardiometabolic Diseases. 2017. |
| Researcher : Wong HY |
| List of Research Outputs |
| Wong H.Y., LEE K.Y. and Cheung C.L., Metabolomics of Sarcopenia in Hong Kong Chinese, The 18th Regional Osteoporosis Conference. Hong Kong. 2017. |
| Wong H.Y., CHENG K.F., LEE K.Y. and Cheung C.L., Plenary Oral Presentation Award, Korean Endocrine Society. 2017. |
| Wong H.Y., CHENG K.F., LEE K.Y. and Cheung C.L., Precision Medicine of Denosumab Monotherapy in Osteoporotic Patients, The 5th Seoul International Congress of Endocrinology and Metabolism, SICEM 2017. |
| Researcher : Wong ICK |
| Project Title: | Feasibility study of the effects of clonidine and melatonin treatment on sleep architecture of children with ADHD. |
| Investigator(s): | Wong ICK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Translational and Applied Research |
| Start Date: | 04/2015 |
| List of Research Outputs |
| Anand S., Tong H.Y.H., Besag F.M.C., Chan E.W., Cortese S. and Wong I.C.K., Safety, Tolerability And Efficacy Of Drugs For Treating Behavioural Insomnia In Children With Attention-deficit/hyperactivity Disorder: A Systematic Review With Methodological Quality Assessment. , Pediatr Drugs . 2017, 19(3): 235-250. |
| Botzenhardt S., Wong I.C.K., Chan E.W., SING C.W. and Neubert A., Safety profiles of iron chelators in young patients with haemoglobinopathies, Eur J Haematol . 2017, 98(3): 198-217. |
| CHUI S.L.C., WONG Y.S., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Potential association between the use of oral fluoroquinolones and acute neuropsychiatric disorders in Hong Kong: a self-controlled case series study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| CHUI S.L.C., Wong I.C.K., WONG Y.S., LEE E.H.M., CHANG W.C., CHEN E.Y.H. and Chan E.W., The Association Between the Use of Oral Fluoroquinolones and Neuropsychiatric Events: A Self-Controlled Case Series Study, 32nd ICPE, Dublin, August 25-28, 2016. |
| Chan P.H.M., Hai S.H.J.J., Huang D., Ho M.H., Chan E.W., Cheung B.M.Y., Wong I.C.K., Tse H.F., Hung F.N.I. and Siu D.C.W., Burden of upper gastrointestinal symptoms in patients prescribed Dabigatran for stroke prevention., Sage Open Medicine . 2016, 4:2050312116662414. |
| Chung A.Y., Anand S., Wong I.C.K., Tan K.C.B., Wong C.F., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong: a multidisciplinary approach, Hong Kong Medical Journal. 2017, 23(2): 158-67. |
| Chung A.Y.S., Anand S., Wong I.C.K., Tan K.C.B., Wong F.F.C., Chui C.M.W. and Chan E.W., Improving medication safety and diabetes management in Hong Kong – A multi-disciplinary approach., Hong Kong Med. J. . 2017, 23(2): 158-167. |
| He Y.H., Wong I.C.K., Li X., Anand S., Leung W.K., Siu D.C.W. and Chan E.W., The association between non-vitamin K antagonist oral anticoagulants and gastrointestinal bleeding: a meta-analysis of observational studies, British Journal of Clinical Pharmacology. 2016, 82(1): 285-300. |
| LAO S., Chan E.W., Man K.C.K. and Wong I.C.K., Antipsychotic Prescription Trend in Hong Kong from 2004 to 2014, 32nd ICPE, Dublin, August 25-28, 2016. |
| LAO S., HE Y., Wong I.C.K., BESAG F.M.C. and Chan E.W., Tolerability/Safety Profile of Cariprazine in Treating Psychotic Disorders/Bipolar Disorder: A Systematic Review with Meta-Analysis of RCTs , 32nd ICPE, Dublin, August 25-28, 2016. |
| LAU C.Y., Li X., Wong I.C.K. and Chan E.W., Bleeding-related hospital admissions and 30-day readmission with dabigatran versus warfarin in patients with non-valvular atrial fibrillation, ISPOR, Boston USA, 20-24th May (Poster) 2017. |
| LAU C.Y., Chan E.W. and Wong I.C.K., Dabigatran versus Warfarin in Patients with Non-Valvular Atrial Fibrillation: A Population-Wide Cohort Study in Chinese Patients. , ICPE, Dublin, Ireland, 25-28th August.. 2016. |
| LAU C.Y., Li X., Wong I.C.K. and Chan E.W., Hospitalization and Length of Stay among Patients with Non-Valvular Atrial Fibrillation Taking Dabigatran or Warfarin: A Population-Based Cohort Study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| Leung Y.H., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., 25-hydroxyvitamin D and the risk of incident diabetes in Hong Kong Chinese., Presented at the 13th Congress of the European Association for Clinical Pharmacology and Therapeutics, Prague, 2017.. 2017. |
| Leung Y.H., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., 25-hydroxyvitamin D and the risk of incident diabetes in Hong Kong Chinese., Presented at the 5th Seoul International Congress of Endocrinology and Metabolism 2017.. 2017. |
| Leung Y.H., Han Y., SING C.W., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., Serum 25-hydroxyvitamin D and the risk of stroke in Hong Kong Chinese., Presented at the 20th Anniversary Scientific Meeting of the Institute of Cardiovascular Science and Medicine, 2016.. 2016. |
| Leung Y.H., Han Y., SING C.W., Cheung B.M.Y., Wong I.C.K., Tan K.C.B., Kung A.W.C. and Cheung C.L., Serum 25-hydroxyvitamin D and the risk of stroke in Hong Kong Chinese, Thrombosis and Haemostasis. 2016, 117: 158-163. |
| Li W., Huang D., Chiang C.E., Lau C.P., Tse H.F., Chan E.W., Wong I.C.K., Lip G., Chan P.H.M. and Siu D.C.W., Efficacy and Safety of Dabigatran, Rivaroxaban and Warfarin for Stroke Prevention in patients with Atrial Fibrillation: The Hong Kong Atrial Fibrillation Project, Clin Cardiol. 2017, 40(4): 222-229. |
| Man K.C.K., Li X., Chan E.W. and Wong I.C.K., The Long term use of biologics in Hong Kong., ICPE, Dublin, Ireland, 25-28th August. 2016. |
| SING C.W., Wong I.C.K., Cheung B.M.Y., Chan C.Y.J., Chu K.P.J. and Cheung C.L., Incidence and risk estimate of drug-induced agranulocytosis in Hong Kong Chinese. A population-based case-control study, Pharmacoepidemiology and Drug Safety. 2017, 26: 248-255. |
| WONG Y.S., Chan E.W., Anand S., Worsley A.J. and Wong I.C.K., Managing cardiovascular risk of macrolides: systematic review and meta-analysis. , Drug Saf . 2017. |
| WONG Y.S., Wong I.C.K., CHUI S.L.C., LEE E.H.M., CHANG W.C., CHEN E.Y.H., LEUNG W.K. and Chan E.W., Neuropsychiatric Events Associated with the Use of Helicobacter Pylori Eradication Therapy Containing-Clarithromycin: Self-Controlled Case Series, 32nd ICPE, Dublin, August 26-28, 2016. |
| Researcher : Wong KC |
| List of Research Outputs |
| LAM C.S., Tipoe G.L., Wong K.C., Youdim M.B.H. and Fung M.L., M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus, In: Kenji Hashimoto, Chiba Daigaku, PLoS ONE. 2016. |
| Researcher : Wong YS |
| List of Research Outputs |
| CHUI S.L.C., WONG Y.S., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Potential association between the use of oral fluoroquinolones and acute neuropsychiatric disorders in Hong Kong: a self-controlled case series study., ICPE, Dublin, Ireland, 25-28th August . 2016. |
| CHUI S.L.C., Wong I.C.K., WONG Y.S., LEE E.H.M., CHANG W.C., CHEN E.Y.H. and Chan E.W., The Association Between the Use of Oral Fluoroquinolones and Neuropsychiatric Events: A Self-Controlled Case Series Study, 32nd ICPE, Dublin, August 25-28, 2016. |
| Leung W.K., Chan E.W., Wong Y.S., Chen L., Wong O.L., Wong I.C. and Cheung M.K.S., Age of Helicobacter pylori Eradication and Subsequent Risk of Gastric Cancer Development: A Population-Based Study, Digestive Disease Week, 6-9 May 2017, Chicago, USA. 2017. |
| WONG Y.S., Chan E.W., Anand S., Worsley A.J. and Wong I.C.K., Managing cardiovascular risk of macrolides: systematic review and meta-analysis. , Drug Saf . 2017. |
| WONG Y.S., Wong I.C.K., CHUI S.L.C., LEE E.H.M., CHANG W.C., CHEN E.Y.H., LEUNG W.K. and Chan E.W., Neuropsychiatric Events Associated with the Use of Helicobacter Pylori Eradication Therapy Containing-Clarithromycin: Self-Controlled Case Series, 32nd ICPE, Dublin, August 26-28, 2016. |
| Researcher : Woo WHC |
| Project Title: | Role of gut microbiota and prebiotics on glucose metabolism during pregnancy |
| Investigator(s): | Woo WHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2015 |
| Project Title: | Maternal Lipid Trafficking mediated by Gut Microbiota and TLR5 |
| Investigator(s): | Woo WHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| Project Title: | Keystone Symposium: Integrating Metabolism and Immunity ; Anticipation of toll-like receptor 5 in atherosclerosis via regulation of lipoproteins |
| Investigator(s): | Woo WHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2017 |
| Completion Date: | 06/2017 |
| Project Title: | Anticipation of Gut Microbiota in Atheroprotection via TLR5 signaling |
| Investigator(s): | Woo WHC |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| List of Research Outputs |
| CHEN J. and Woo W.H.C., Metabolic Function of TIR-Domain-containing Adaptor-inducing Interferon-b (TRIF) in Diet-induced obesity, The University of Hong Kong. 2016. |
| CHEN J., LI J., Xu A. and Woo W.H.C., Metabolic Function of TIR-Domain-containing adapter-inducing interferon-b (TRIF) in hepatocytes, In: Federation of American Societies for Experimental Biology, FASEB Science Research Conference: Immunological Aspects of Obesity. 2016. |
| CHEN J., Li J., Xu A. and Woo W.H.C., Metabolic function of TIR-domain-containing adapter-inducing interferon-b (TRIF) in hepatocytes, FASEB Science Research Conferences, July 31- August 5, 2016, Big Sky, Montana. 2016. |
| GENG L., LIAO B., JIN L., HUANG Z., Woo W.H.C., Lam K.S.L. and Xu A., Chronic exercise alleviated dietary obesity-associated metabolic dysfunction by enhancing FGF-21 sensitivity in adipose tissues., The 99th Annual Meeting of the American Endocrine Society, 1-4 April 2017, Orlando, USA. 2017. |
| Li J. and Woo W.H.C., Finding ways to solve or prevent aminoglycoside-induced ototoxicity?, Annals of Translational Medicine. 2016, 4: 533-533. |
| Shang Y., Khafipour E., Derakhshani H., Sarna L.K., Woo W.H.C., Siow Y.L. and O K., Short Term High Fat Diet Induces Obesity-Enhancing Changes in Mouse Gut Microbiota That are Partially Reversed by Cessation of the High Fat Diet., Lipids. Springer, 2017, 52: 499-511. |
| YIU J.H.C., Dorweiler B. and Woo W.H.C., Interaction between Gut Microbiota and Toll-like Receptor: from Immunity to Metabolism, Journal of Molecular Medicine. 2016. |
| YIU J.H.C. and Woo W.H.C., The Commensal role of Gut microbiota in Pregnancy via Toll-like receptor 5, The University of Hong Kong. 2017. |
| Yiu J.H.C., Xu A. and Woo W.H.C., Anticipation of toll-like receptor 5 in atherosclerosis via regulation of lipoproteins, Keystone Symposium: Integrating Metabolism and Immunity, Dublin, 29May-2Jun, 2017. |
| Researcher : Worsley AJ |
| List of Research Outputs |
| WONG Y.S., Chan E.W., Anand S., Worsley A.J. and Wong I.C.K., Managing cardiovascular risk of macrolides: systematic review and meta-analysis. , Drug Saf . 2017. |
| Researcher : XU Y |
| List of Research Outputs |
| XU Y., Liang W., Qiu Y., Cespi M., Palmieri G.F., Mason A.J. and Lam J.K.W., Incorporation of a nuclear localization signal in pH responsive LAH4-L1 peptide enhances transfection and nuclear uptake of plasmid DNA, Molecular Pharmaceutics. 2016, 13: 3141-3152. |
| Researcher : Xu C |
| Project Title: | Selective overexpression of SIRT1 in adipose tissue protects adiponectin deficiency induced liver injury |
| Investigator(s): | Xu C, Wang Y |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2017 |
| List of Research Outputs |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu C. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31: Suppl 998.10. |
| Researcher : YANG K |
| List of Research Outputs |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu C. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31: Suppl 998.10. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu A. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31. |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| YANG K., Role of Lipocalin-2 Deficiency in Cardio-renal Damages, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| Researcher : YING F |
| List of Research Outputs |
| YING F. and Tang E.H.C., Deficiency of Prostaglandin E Receptor Subtype 4 (EP4) Favored Multilocular Fat Cell Formation and Increased Mitochondrial Biogenesis through the AMPK-FSP27 Axis, 12th International Symposium on Healthy Aging, 11-12 March 2017, Hong Kong. 2017. |
| YING F., Cai Y., Wong H.K., Lee T. and Tang E.H.C., Disturbed cholesterol homeostasis in prostaglandin E receptor 4 knockout mice model, The 6th ICCR Congress on Chronic societal Cardiometabolic Diseases. 2017. |
| YING F., Cai Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 (EP4) regulates lipid droplet size and mitochondrial activity via FSP27 in white adipose tissue, Metabolic Diseases; Breakthrough Discoveries in Diabetes & Obesity, Novotel Melbourne St Kilda, 1-2 December 2016. |
| YING F., Cai Y., CAI Y., Wang Y. and Tang E.H.C., Prostaglandin E receptor subtype 4 regulates lipid droplet size and mitochondrial activity in murine subcutaneous white adipose tissue, The FASEB Journal. 2017, 331: 4023-4036. |
| YING F., Cai Y. and Tang E.H.C., Prostaglandin receptor subtype 4 (EP4) deficiency enhanced multilocular fat cell formation and mitochondrial biogenesis and facilated wat remodeling, The 6th ICCR Congress on Chronic Societal Cardiometabolic Diseases, May 15-17, 2017, Quebec Canada. 2017. |
| Researcher : YIU JHC |
| List of Research Outputs |
| YIU J.H.C., Dorweiler B. and Woo W.H.C., Interaction between Gut Microbiota and Toll-like Receptor: from Immunity to Metabolism, Journal of Molecular Medicine. 2016. |
| YIU J.H.C. and Woo W.H.C., The Commensal role of Gut microbiota in Pregnancy via Toll-like receptor 5, The University of Hong Kong. 2017. |
| Yiu J.H.C., Xu A. and Woo W.H.C., Anticipation of toll-like receptor 5 in atherosclerosis via regulation of lipoproteins, Keystone Symposium: Integrating Metabolism and Immunity, Dublin, 29May-2Jun, 2017. |
| Researcher : Yang K |
| List of Research Outputs |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu C. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31: Suppl 998.10. |
| Sun W.Y., Yang K., Luo C., Feletou M., Villeneuve N., Vanhoutte P.M.G.R., Xu A. and Wang Y., Role of lipocalin-2 in dietary and aldosterone-induced renal damages, Experimental Biology 2017. The FASEB, 31. |
| YANG K., Deng H., MAN W.C., SONG E., Zhang J., Luo C., Cheung B.M.Y., Yuen K.Y., Jensen P.S., Irmukhamedov A., Elie A...G...I...M., Vanhoutte P.M.G.R., Xu A., De Mey J.G.R. and Wang Y., Measuring non-polyaminated lipocalin-2 for cardiometabolic risk assessment, ESC Heart Failure. 2017, 1-13. |
| YANG K., Role of Lipocalin-2 Deficiency in Cardio-renal Damages, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| Researcher : Ye D |
| Project Title: | Lipocalin-2 in acute and chronic liver diseases: focusing on neutrophil-mediated innate immune responses |
| Investigator(s): | Ye D, Wang Y, Wong ICK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 10/2013 |
| Completion Date: | 05/2017 |
| Project Title: | Gut Microbiota Modulation of Host Physiology: The Search for Mechanism (C1); Neutrophil-derived Lipocalin-2 Mediates Nonalcoholic Steatohepatitis through Modulating Crosstalk between Mucosa Immunity and Gut Microbiota |
| Investigator(s): | Ye D |
| Department: | Medicine |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 03/2015 |
| Researcher : ZHANG P |
| List of Research Outputs |
| ZHANG P., Effects of Genistein on Cigarette Smoke-induced inflammatory Responses in Human Bronchial Epithelial BEAS-2B Cells and in Rats, 21st Research Postgraduate Symposium, December 1-2, 2016, Hong Kong. 2016. |
| ZHANG P., Mak J.C.W., Man R.Y.K. and Leung S.W.S., Effects of genistein on inflammatory responses in cigarette smoke-exposed rats, Pharmacology 2016, The Queen Elizabeth II Conference Centre, London, 13-15 December, 2016. |