SCHOOL OF CHINESE MEDICINE



Researcher : CHEN F
List of Research Outputs

CHEN F., Wang N., Tan H.Y.H., GUO W., ZHANG C. and Feng Y., The functional roles of exosomes-derived long non-coding RNA in human cancer, Cancer Biology & Therapy. 2019, 1-10.
Wang N., Tan H.Y.H., Feng Y.G., ZHANG C., CHEN F. and Feng Y., microRNA-23a in Human Cancer: Its Roles, Mechanisms and Therapeutic Relevance, Cancers. 2018, 11: 7.


Researcher : CHEN X
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
FENG J., Chen X. and Shen J., Inhibition of peroxynitrite-induced mitophagy activation attenuates cerebral ischemia-reperfusion injury, Molecular Neurobiology. 2018, 55: 6369-6386.
FENG J., Chen X., Lu S., LI W., Wang Q., Xu A. and Shen J., Naringin attenuates cerebral ischemia-reperfusion injury through inhibiting peroxynitrite-mediated mitophagy activation, Molecular Neurobiology . 2018, 2018.
Gao C., Chen X., Xu A., Cheng K.Y. and Shen J., Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor, Molecular Neurobiology. 2018, 55: 5537-5547.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.
Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.


Researcher : CHENG Y
List of Research Outputs

CHENG Y., YANG C., LUO D., Li X.C., Le X.C. and Rong J., N-Propargyl Caffeamide Skews Macrophages Towards a Resolving M2-Like Phenotype Against Myocardial Ischemic Injury via Activating Nrf2/HO-1 Pathway and Inhibiting NF-ĸB Pathway, Cellular Physiology and Biochemistry. 2018, 47: 2544-2557.


Researcher : Chan WCC
List of Research Outputs

Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.


Researcher : Chan YT
List of Research Outputs

Xue X.T., Tan H.Y.H., Teng S.T., Chan Y.T., Wang D.W. and Wang N., The Role of AMP-Activated Protein Kinase as a Potential Target of Treatment of Hepatocellular Carcinoma, Cancers. 2019, 11: 647.


Researcher : Chen H
Project Title:The latent TGF-β protects against diabetic kidney disease via GARP-latent TGF-β mediated anti-inflammation: mechanism and therapeutic potential
Investigator(s):Chen H, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2017


Project Title:A novel small molecule from Lingzhi ameliorates cisplatin-induced acute kidney Injury via AMPK/mTOR-MAPK-NFkB crosstalk pathways: a pilot study
Investigator(s):Chen H, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2017
Completion Date:12/2018


Project Title:The 4th American TCM Congress; Acupressure for labor pain management: a systemic review and meta-analysis of randomized controlled trials/Acupuncture for diabetic peripheral neuropathy: a systematic review of randomized controlled trials
Investigator(s):Chen H
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2018
Completion Date:08/2018


Project Title:The role of small molecules from Ganoderma on uric acid nephropathy
Investigator(s):Chen H, Lao L, You Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2019


List of Research Outputs

Au Yeung Y. and Chen H., A systematic review of systematic reviews and meta-analysis of Chinese herbs on diabetic nephropathy, The 17th CGCM Meeting. 2018.
Chen H., Yang C., NING Z., LAM W.L., ZHAO Y., Yeung W.F., Ng B.F.L., Ziea E.T.C. and Lao L., A Guideline for Randomized Controlled Trials of Acupuncture, The American Journal of Chinese Medicine. 2019, 1-18.
Chen H., Yang C. and Lao L., Acupuncture for Women Undergoing In Vitro Fertilization, JAMA. 2018, 320: 1385.
Chen H. and Liu N.Y., Analgesic Effect of Sinew Acupuncture for Patients with Soft-Tissue Injuries: A Pilot Trial, Chinese Journal of Integrative Medicine. 2019.
Chen H. and Shen J., Angong Niuhuang Pill (ANP) attenuated hemorrhagic transformation and improved neurological outcomes in ischemic stroke with delayed tissue plasminogen activator (t-PA) treatment, possibly through inhibiting peroxynitrite-MMP9 signaling pathway, The 4th global Chinese Symposium & The 8th Symposium for cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Chen H. and Shen J., Angong Niuhuang Pill Prevents Hemorrhagic Transformation and promotes Outcome in Ischemic Stroke with Delayed t-PA treatment, possibly through Inhibiting Peroxynitrite-Mediated HMGB1/MMP-9 Signaling Cascades, 14th International Symposium on Healthy Aging. 2019.
Chen H. and Shen J., Best Presentation award, The 4th Global Chinese Symposium & The 8th Symposium for Cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Chen H. and Shen J., Chinese Herbal Medicine: A Great Opportunity for Reducing Thrombolysis-mediated Hemorrhagic Transformation in Ischemic Stroke Treatment, 6 th Macau Symposium on Biomedical Sciences 2019. 2019.
Chen H., Diabetic nephropathy: mechanism discovery and therapeutic approaches, The 11th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2018.
Chen H., Chen X., Luo Y. and Shen J., Potential molecular targets of peroxynitrite in mediating blood–brain barrier damage and haemorrhagic transformation in acute ischaemic stroke with delayed tissue plasminogen activator treatment, Free Radical Research. 2018, 1-20.
Chen H., Role of TGF-β1/Smad signaling in diabetic nephropathy, Mainland-Hong Kong Frontier Discipline Forum - Nephrology: From Bench To Bedside. 2019.
Chen H. and Tong Y., Systematic Reviews and Meta-Analyses, Professional English for Scientific Research in Traditional Chinese Medicine. Beijing, People's Medical Publishing House, 2018, 1-28.
Chen H., Travel Award at 2018 World Life Science Conference, China Association for Science and Technology. 2018.
Chen X., Chen H., Peng C. and Shen J., Active compounds and molecular targets of Chinese herbal medicine for neurogenesis in stroke treatment: Implication for cross talk between Traditional Chinese Medicine and Biomedical Sciences, World Journal of Traditional Chinese Medicine. 2019, 5: 104.
Chen X., WU H., Chen H., Wang Q., Xie X. and Shen J., Astragaloside VI Promotes Neural Stem Cell Proliferation and Enhances Neurological Function Recovery in Transient Cerebral Ischemic Injury via Activating EGFR/MAPK Signaling Cascades, Molecular Neurobiology. 2018, 56(4): 3053-3067.
Chen Y., Xiang X., Wu J., Lao L. and Chen H., Acupressure for labor pain management: a systemic review and meta-analysis of randomized controlled trials, the Fourth American TCM Congress. 2018.
Cho W.C.S., Li C. and Chen H., Clinical efficacy of acupoint embedment in weight control, Medicine. 2018, 97: e12267.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.
LIU X., HU J., Lao L., Chen H. and Wu J., The efficacy of anti-hypertension by self-stimulation on channel-skin regions of hands and feet for Hypertension：A pilot study, the Fourth American TCM Congress, Seattle, USA, 4-5/08/2018, hosted by TCM American Alumni Association. 2018.
Lao L. and Chen H., How to Design, Conduct and Report a Randomized Controlled Trial on Acupuncture, Professional English for Scientific Research in Traditional Chinese Medicine. Beijing, People's Medical Publishing House, 2018, 230-245.
Leung C.T., Tsang K.W. and Chen H., The efficacy of acupuncture for diabetic gastroparesis: a systematic review and meta-analysis, The 17th CGCM Meeting. 2018.
Leung K.K., Tsang K., Ting H., Ma C.H., Lun K.K., Ho T., Chu C.Y.T., Chan H.Y.F., Chou L., Wen G.Y., Ng J.T., Lau A., Jiang F., Ng B.F.L., Ziea E., Lao L., Fok M.W.M., Fang C.X. and Chen H., Sinew acupuncture for de Quervain's Tenosynovitis (dQt): a randomised controlled trial, Advances in Integrative Medicine. 2019, 6: S84.
Lin R., Duan Z., Sun H., Fung M.L., Chen H., Wang J., Lau C.F., Yang D., Liu Y., Ni Y., Wang Z., Cui J., Wu W., Yung W.H., Chan Y.S., Lo A.C.Y., Xia J., Shen J. and Huang J., Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity, iScience. 2019, 13: 82-97.
Shen J., FENG J. and Chen H., Peroxynitrite-mediated mitophagy could be a crucial therapeutic target for reducing cerebral ischemia–reperfusion injury, The 4th Global Chinese Symposium & the 8th Symposium for Cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Shen J., FENG J. and Chen H., Peroxynitrite‑mediated mitophagy could be a crucial therapeutic target for reducing cerebral ischemia–reperfusion injury, 4th Global Chinese Symposium and the 8th Symposium for cross-straits, Hong Kong and Macao on free radical biology and medicine. 2018, 13: 56.
Tsang K.W., Leung C.T., Au Yeung Y., Lao L., Wu J. and Chen H., Acupuncture for diabetic peripheral neuropathy: a systematic review of randomized controlled trials, The Fourth American TCM Congress. 2018.
WU W., Wang J., Chen H. and Meng X.M., 7-hydroxycoumarin protects against acute kidney injury by inhibiting necroptosis and promoting Sox-9-mediated cell proliferation, ISN World Congress of Nephrology 2019.
WU W., Huang X.R., You Y., Chen H. and Lan H.Y., Latent TGF-β protects against diabetic kidney disease via GARP-latent TGF-β mediated anti-inflammation, ISN World Congress of Nephrology 2019.
You Y., Luo Q., WU W., Zhang J., Zhu H.J., Lao L., Lan H.Y., Chen H. and Cheng Y., Petchiether A attenuates obstructive nephropathy by suppressing TGF-β/Smad3 and NF-κB signalling, Journal of Cellular and Molecular Medicine. 2019.
You Y., Huang X.R., WU W., Chen H. and Lan H.Y., Restoration of PGC-1α activity by Smad3 deficiency protects against CRP-exacerbated kidney injury after unilateral ureteral obstruction, ISN World Congress of Nephrology 2019.


Researcher : Chen H
List of Research Outputs

Au Yeung Y. and Chen H., A systematic review of systematic reviews and meta-analysis of Chinese herbs on diabetic nephropathy, The 17th CGCM Meeting. 2018.
Chen H., Yang C., NING Z., LAM W.L., ZHAO Y., Yeung W.F., Ng B.F.L., Ziea E.T.C. and Lao L., A Guideline for Randomized Controlled Trials of Acupuncture, The American Journal of Chinese Medicine. 2019, 1-18.
Chen H., Yang C. and Lao L., Acupuncture for Women Undergoing In Vitro Fertilization, JAMA. 2018, 320: 1385.
Chen H. and Liu N.Y., Analgesic Effect of Sinew Acupuncture for Patients with Soft-Tissue Injuries: A Pilot Trial, Chinese Journal of Integrative Medicine. 2019.
Chen H. and Shen J., Angong Niuhuang Pill (ANP) attenuated hemorrhagic transformation and improved neurological outcomes in ischemic stroke with delayed tissue plasminogen activator (t-PA) treatment, possibly through inhibiting peroxynitrite-MMP9 signaling pathway, The 4th global Chinese Symposium & The 8th Symposium for cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Chen H. and Shen J., Angong Niuhuang Pill Prevents Hemorrhagic Transformation and promotes Outcome in Ischemic Stroke with Delayed t-PA treatment, possibly through Inhibiting Peroxynitrite-Mediated HMGB1/MMP-9 Signaling Cascades, 14th International Symposium on Healthy Aging. 2019.
Chen H. and Shen J., Best Presentation award, The 4th Global Chinese Symposium & The 8th Symposium for Cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Chen H. and Shen J., Chinese Herbal Medicine: A Great Opportunity for Reducing Thrombolysis-mediated Hemorrhagic Transformation in Ischemic Stroke Treatment, 6 th Macau Symposium on Biomedical Sciences 2019. 2019.
Chen H., Diabetic nephropathy: mechanism discovery and therapeutic approaches, The 11th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2018.
Chen H., Chen X., Luo Y. and Shen J., Potential molecular targets of peroxynitrite in mediating blood–brain barrier damage and haemorrhagic transformation in acute ischaemic stroke with delayed tissue plasminogen activator treatment, Free Radical Research. 2018, 1-20.
Chen H., Role of TGF-β1/Smad signaling in diabetic nephropathy, Mainland-Hong Kong Frontier Discipline Forum - Nephrology: From Bench To Bedside. 2019.
Chen H. and Tong Y., Systematic Reviews and Meta-Analyses, Professional English for Scientific Research in Traditional Chinese Medicine. Beijing, People's Medical Publishing House, 2018, 1-28.
Chen H., Travel Award at 2018 World Life Science Conference, China Association for Science and Technology. 2018.
Chen X., Chen H., Peng C. and Shen J., Active compounds and molecular targets of Chinese herbal medicine for neurogenesis in stroke treatment: Implication for cross talk between Traditional Chinese Medicine and Biomedical Sciences, World Journal of Traditional Chinese Medicine. 2019, 5: 104.
Chen X., WU H., Chen H., Wang Q., Xie X. and Shen J., Astragaloside VI Promotes Neural Stem Cell Proliferation and Enhances Neurological Function Recovery in Transient Cerebral Ischemic Injury via Activating EGFR/MAPK Signaling Cascades, Molecular Neurobiology. 2018, 56(4): 3053-3067.
Chen Y., Xiang X., Wu J., Lao L. and Chen H., Acupressure for labor pain management: a systemic review and meta-analysis of randomized controlled trials, the Fourth American TCM Congress. 2018.
Cho W.C.S., Li C. and Chen H., Clinical efficacy of acupoint embedment in weight control, Medicine. 2018, 97: e12267.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.
LIU X., HU J., Lao L., Chen H. and Wu J., The efficacy of anti-hypertension by self-stimulation on channel-skin regions of hands and feet for Hypertension：A pilot study, the Fourth American TCM Congress, Seattle, USA, 4-5/08/2018, hosted by TCM American Alumni Association. 2018.
Lao L. and Chen H., How to Design, Conduct and Report a Randomized Controlled Trial on Acupuncture, Professional English for Scientific Research in Traditional Chinese Medicine. Beijing, People's Medical Publishing House, 2018, 230-245.
Leung C.T., Tsang K.W. and Chen H., The efficacy of acupuncture for diabetic gastroparesis: a systematic review and meta-analysis, The 17th CGCM Meeting. 2018.
Leung K.K., Tsang K., Ting H., Ma C.H., Lun K.K., Ho T., Chu C.Y.T., Chan H.Y.F., Chou L., Wen G.Y., Ng J.T., Lau A., Jiang F., Ng B.F.L., Ziea E., Lao L., Fok M.W.M., Fang C.X. and Chen H., Sinew acupuncture for de Quervain's Tenosynovitis (dQt): a randomised controlled trial, Advances in Integrative Medicine. 2019, 6: S84.
Lin R., Duan Z., Sun H., Fung M.L., Chen H., Wang J., Lau C.F., Yang D., Liu Y., Ni Y., Wang Z., Cui J., Wu W., Yung W.H., Chan Y.S., Lo A.C.Y., Xia J., Shen J. and Huang J., Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity, iScience. 2019, 13: 82-97.
Shen J., FENG J. and Chen H., Peroxynitrite-mediated mitophagy could be a crucial therapeutic target for reducing cerebral ischemia–reperfusion injury, The 4th Global Chinese Symposium & the 8th Symposium for Cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Shen J., FENG J. and Chen H., Peroxynitrite‑mediated mitophagy could be a crucial therapeutic target for reducing cerebral ischemia–reperfusion injury, 4th Global Chinese Symposium and the 8th Symposium for cross-straits, Hong Kong and Macao on free radical biology and medicine. 2018, 13: 56.
Tsang K.W., Leung C.T., Au Yeung Y., Lao L., Wu J. and Chen H., Acupuncture for diabetic peripheral neuropathy: a systematic review of randomized controlled trials, The Fourth American TCM Congress. 2018.
WU W., Wang J., Chen H. and Meng X.M., 7-hydroxycoumarin protects against acute kidney injury by inhibiting necroptosis and promoting Sox-9-mediated cell proliferation, ISN World Congress of Nephrology 2019.
WU W., Huang X.R., You Y., Chen H. and Lan H.Y., Latent TGF-β protects against diabetic kidney disease via GARP-latent TGF-β mediated anti-inflammation, ISN World Congress of Nephrology 2019.
You Y., Luo Q., WU W., Zhang J., Zhu H.J., Lao L., Lan H.Y., Chen H. and Cheng Y., Petchiether A attenuates obstructive nephropathy by suppressing TGF-β/Smad3 and NF-κB signalling, Journal of Cellular and Molecular Medicine. 2019.
You Y., Huang X.R., WU W., Chen H. and Lan H.Y., Restoration of PGC-1α activity by Smad3 deficiency protects against CRP-exacerbated kidney injury after unilateral ureteral obstruction, ISN World Congress of Nephrology 2019.


Researcher : Chen J
Project Title:The development of multimedia tearching and learning system in TCM -prescrption subject
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:07/2011


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A (ITS/073/11FP)
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:Ninth AACR-Japanese Cancer Association Joint Conference: Breakthroughs in Basic and Translational Cancer Research; Isoliquiritigenin promotes breast cancer chemosensitivity by limiting cancer stem cells targeting aberrant β-catenin signaling
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:02/2013


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2013


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2013


Project Title:Development of tea bag YH0618, an herbal dietary supplement against chemotherapy-induced toxicity
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Matching Grant for Joint Research
Start Date:08/2015


Project Title:Development of Tea Bag YH0618, an Herbal Dietary Supplement against Chemotherapy-induced Toxicity
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2015


Project Title:Development of Tea Bag YH0618, an Herbal Dietary Supplement against Chemotherapy-induced Toxicity
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:10/2015


Project Title:The inhibitory effect of Suberect Spatholobus on the migration of breast cancer via Wnt/β-catenin pathway induced by miRNA
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2016


Project Title:Reduction of chemotherapy-induced toxicity in cancer patients after chemotherapy using a medical food YH0618: a pilot controlled trial
Investigator(s):Chen J, He Y, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:03/2017


Project Title:A safety issue of Traditional Chinese Medicine: Whether it is appropriate to use a famous Chinese medicine Radix Angelicae Sinensis (Danggui) on women with breast cancer
Investigator(s):Chen J, Tang H, Jia L
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2017
Completion Date:05/2019


Project Title:Preclinical study of a novel drug (Spatholobus Suberectus Dunn's extract) by chemosensitizing the paclitaxel on treating triple-negative breast cancer.
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:06/2018


Project Title:Traditional and Alternative Medicine" (Traditional Medicine-2019) ; “Metabonomics study of ethanol extract from Caulis Spatholobi（EECS）on weight loss via energy metabolism (Final report: Metabonomics study of ethanol extract from Spatholobus suberectus (EESS) on weight loss via energy metabolism)
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2019
Completion Date:06/2019


List of Research Outputs

Chen J., Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway, 2019.
Chen J., Elucidating the therapeutic effect of natural compound isoliquiritigenin on breast cancer in microRNA regulation network, 2018.
Chen J., Metabonomics study of ethanol extract from CaulisSpatholobi EECS on weight loss via energy metabolism, 2019.
Chen J., TCM music causes remission of promoted breast cancer growth by managing depression-like behaviours in mice and in clinic, 2019.
Chen J., 健康你话事, 2018.
Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019.
WANG N., zhang X., Chen J., xiang D. and wang Z.H.I., 中醫藥干預惡性腫瘤轉移新模式——靶向調控預轉移, 環球中醫藥, 2019.
YOU J., GAO F., PENG F., Tang H., LIU H. and Chen J., A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4, 2019.
YOU J., LIU H. and Chen J., 陳建萍從肝論治乳腺癌思路與經驗, 2018.


Researcher : Chen X
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
FENG J., Chen X. and Shen J., Inhibition of peroxynitrite-induced mitophagy activation attenuates cerebral ischemia-reperfusion injury, Molecular Neurobiology. 2018, 55: 6369-6386.
FENG J., Chen X., Lu S., LI W., Wang Q., Xu A. and Shen J., Naringin attenuates cerebral ischemia-reperfusion injury through inhibiting peroxynitrite-mediated mitophagy activation, Molecular Neurobiology . 2018, 2018.
Gao C., Chen X., Xu A., Cheng K.Y. and Shen J., Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor, Molecular Neurobiology. 2018, 55: 5537-5547.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.
Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.


Researcher : Cheung F
List of Research Outputs

Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.


Researcher : Choi YM
List of Research Outputs

Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.


Researcher : Deng R
Project Title:Exploring effects of Astragaloside IV, an active component of Astragalus, as an adjunct therapy with radiation therapy and/or chemotherapy to promote haematopoiesis in cancer treatment
Investigator(s):Deng R, Shen J, Chan GCF
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2017


List of Research Outputs

Deng R., Law H.Y., Shen J. and Chan G.C.F., Mini Review: Application of Human Mesenchymal Stem Cells in Gene and Stem Cells Therapy Era, In: G. Almeida-Porada; D.S. Krause, Current Stem Cell Reports. Springer International Publishing, 2018, 4: 327-337.
Liang R., Law H.Y., Deng R., Boheler K., Chan H.S.S. and Chan G.C.F., Best Poster Presentation Award ‘Generation of Induced pluripotent stem cells from Peripheral Blood Mononuclear Cells of an X-linked Dilated Cardiomyopathy Patient. R Liang, MR Deng, AHY Law, K Boheler, SHS Chan*, GCF Chan*.[PI and supervisor], The 2nd Joint Annual Research and Scientific Meeting 2018. 2018.
Liang R., Deng R., Law H.Y., Chan H.S.S., Boheler K. and Chan G.C.F., Generation of Induced pluripotent stem cells from Peripheral Blood Mononuclear Cells of an X-linked Dilated Cardiomyopathy Patient., The 2nd Joint Annual Research & Scientific Meeting 2018. Hong Kong.. 2018.


Researcher : FENG J
List of Research Outputs

FENG J., Chen X. and Shen J., Inhibition of peroxynitrite-induced mitophagy activation attenuates cerebral ischemia-reperfusion injury, Molecular Neurobiology. 2018, 55: 6369-6386.
FENG J., Chen X., Lu S., LI W., Wang Q., Xu A. and Shen J., Naringin attenuates cerebral ischemia-reperfusion injury through inhibiting peroxynitrite-mediated mitophagy activation, Molecular Neurobiology . 2018, 2018.
Shen J., FENG J. and Chen H., Peroxynitrite-mediated mitophagy could be a crucial therapeutic target for reducing cerebral ischemia–reperfusion injury, The 4th Global Chinese Symposium & the 8th Symposium for Cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Shen J., FENG J. and Chen H., Peroxynitrite‑mediated mitophagy could be a crucial therapeutic target for reducing cerebral ischemia–reperfusion injury, 4th Global Chinese Symposium and the 8th Symposium for cross-straits, Hong Kong and Macao on free radical biology and medicine. 2018, 13: 56.


Researcher : Feng Y
Project Title:Inhibitory effect of geniposide on hepatocellular carcinoma: the role of Hiwi
Investigator(s):Feng Y, Tsao GSW, Man K, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2016
Completion Date:10/2018


Project Title:Secondary Development of Classical Chinese Medicine Formula Huanglian Jiedu Decoction (HLJDD): HLJDD Reducing Chemotherapy-induced Diarrhoea and Improving Chemotherapy Response
Investigator(s):Feng Y, Wang N, Cheung F
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:03/2017


Project Title:HKU Overseas Fellowship Awards 2017-18
Investigator(s):Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:HKU Overseas Fellowship Awards
Start Date:06/2017


Project Title:Metabolomic study to reveal the mechanism underlying the anti-tumor activity of Chinese Medicine formula Zuo-Jin Wan on human hepatocellular carcinoma (HCC)
Investigator(s):Feng Y, Wang N
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2017
Completion Date:06/2019


Project Title:Secondary Development of Classical Chinese Medicine Formula Huanglian Jiedu Decoction (HLJDD): HLJDD Reducing Chemotherapy-induced Diarrhoea and Improving Chemotherapy Response
Investigator(s):Feng Y, Wang N, Cheung F
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2017


Project Title:Secondary Development of Classical Chinese Medicine Formula Huanglian Jiedu Decoction (HLJDD): HLJDD Reducing Chemotherapy-induced Diarrhoea and Improving Chemotherapy Response
Investigator(s):Feng Y, Wang N, Cheung F
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2017


Project Title:Berberine suppresses metastasis and recurrence of hepatocellular carcinoma via targeting circulating tumour cells
Investigator(s):Feng Y, Yuen RMF, Man K, Zhang Z, Wang N
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2019


Project Title:8th Edition EuroSciCon Conference on Clinical Pharmacy; A Network Pharmacology-Based Study on the Hepatoprotective Effect and Hepatotoxic Effect of Chinese Medicines
Investigator(s):Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2019
Completion Date:04/2019


List of Research Outputs

CHEN F., Wang N., Tan H.Y.H., GUO W., ZHANG C. and Feng Y., The functional roles of exosomes-derived long non-coding RNA in human cancer, Cancer Biology & Therapy. 2019, 1-10.
CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
Chan K.W., Kwong A.S.K., Chan G.C.W., Leung C.P.S., Yiu W.H., Lui S.L., Ip T.P., Cowling B.J., Wong W.L.D., LI B., LI Y., Feng Y., Chan L.Y.Y., Leung J.C.K., Tan K.C.B., Wong C.W.V., Lai K.N. and Tang S.C.W., Best Poster Award, Good Practice In Traditional Chinese Medicine Research Association. 2018.
Chan K.W., Kwong A.S.K., Chan G.C.W., Leung C.P.S., Yiu W.H., Lui S.L., Ip T.P., Cowling B.J., Wong W.L.D., LI B., LI Y., Feng Y., Chan Y.Y., Leung J.C.K., Tan K.C.B., Wong C.W.V., Lai K.N. and Tang S.C.W., Semi-individualised Chinese Medicine Treatment for Diabetic Kidney Disease – From users’ perspectives to SCHEMATIC trial interim result and potential mechanisms, Advances in Integrative Medicine (International Congress on Complementary Medicine Research). 2019, 6: S12.
Feng Y., Tan H.Y.H., Wang N. and Wang L., Endangered species in Chinese medicine: the example of bear bile, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.
Feng Y., LI L., LI S. and Wang N., Study Liver Diseases, TCM In Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Feng Y., The Editorial Board Member , Recent Patents on Recent Patents on Food, Nutrition & Agriculture. USA, BENTHAM SCIENCE PUBLISHERS LTD., 2018.
Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.
LI S., Wang N., Tan H.Y.H., HONG M., Yuen R.M.F., Li H. and Feng Y., Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage, Frontiers in immunology. 2018, 9: 1524.
Qu Y., Dou B., Tan H.Y.H., Feng Y., Wang N. and Wang D., Tumor microenvironment-driven non-cell-autonomous resistance to antineoplastic treatment, Molecular Cancer. 2019, 18.
Tan H.Y.H., Wang N. and Feng Y., Genetical inhibition of IRE1α in macrophages suppresses hepatocellular carcinoma growth, 25th Biennial Congress of the European Association for Cancer Research. 2018.
Tan H.Y.H., Wang N., Lam W., GUO W., Feng Y. and Cheng Y.C., Targeting tumour microenvironment by tyrosine kinase inhibitor, Molecular Cancer. 2018, 17.
Tan H.Y.H., Wang N. and Feng Y., The anti-tumour effect of mangiferin from Mangifera indica Linn. (Anacardiaceae) leaves on human hepatocellular carcinoma, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.
Wang N., ZHANG C., Tan H.Y.H. and Feng Y., Insulin accelerates progression of diabetic retinopathy through activating HIF-1α/VEGF pathway in retinal endothelial cells, 7th Seoul International Congress of Endocrinology and Metabolism. 2019.
Wang N. and Feng Y., Quality Control Of Chinese Herbal Medicine, Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Wang N., Tan H.Y.H., Feng Y.G., ZHANG C., CHEN F. and Feng Y., microRNA-23a in Human Cancer: Its Roles, Mechanisms and Therapeutic Relevance, Cancers. 2018, 11: 7.
XU Y., Tan H.Y.H., LI S., Wang N. and Feng Y., Panax notoginseng for Inflammation-Related Chronic Diseases: A Review on the Modulations of Multiple Pathways, The American journal of Chinese medicine. 2018, 46: 971-996.
Xu H.X., Zhu G.F. and Feng Y., Anticancer Chinese Medicines: Origen, Chemistry, Pharmacology And Clinical Application, Shanghai, Science Publisher, 2018.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : Fu B
List of Research Outputs

Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.


Researcher : GAO C
List of Research Outputs

Gao C., Chen X., Xu A., Cheng K.Y. and Shen J., Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor, Molecular Neurobiology. 2018, 55: 5537-5547.
LI W., WU H., GAO C., Yang D., Su W., Yang D. and Shen J., Radix Rehmanniae Extract Ameliorates Experimental Autoimmune Encephalomyelitis by Suppressing Macrophage-derived Nitrative Damage., Frontiers in Physiology . 2018, 9: 864.
Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.


Researcher : GAO F
List of Research Outputs

YOU J., GAO F., PENG F., Tang H., LIU H. and Chen J., A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4, 2019.


Researcher : GUO W
List of Research Outputs

CHEN F., Wang N., Tan H.Y.H., GUO W., ZHANG C. and Feng Y., The functional roles of exosomes-derived long non-coding RNA in human cancer, Cancer Biology & Therapy. 2019, 1-10.
Tan H.Y.H., Wang N., Lam W., GUO W., Feng Y. and Cheng Y.C., Targeting tumour microenvironment by tyrosine kinase inhibitor, Molecular Cancer. 2018, 17.


Researcher : Gao C
List of Research Outputs

Gao C., Chen X., Xu A., Cheng K.Y. and Shen J., Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor, Molecular Neurobiology. 2018, 55: 5537-5547.
LI W., WU H., GAO C., Yang D., Su W., Yang D. and Shen J., Radix Rehmanniae Extract Ameliorates Experimental Autoimmune Encephalomyelitis by Suppressing Macrophage-derived Nitrative Damage., Frontiers in Physiology . 2018, 9: 864.
Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.


Researcher : HONG M
List of Research Outputs

LI S., Wang N., Tan H.Y.H., HONG M., Yuen R.M.F., Li H. and Feng Y., Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage, Frontiers in immunology. 2018, 9: 1524.


Researcher : Hao D
List of Research Outputs

Hao D., 針灸及推拿在運動損傷中的應用, 深圳市级继续教育项 目“针刺及推拿特色手 法临床应用培训班 ”, 2018.
Hao D., 肩部筋傷的整體治療, 2019 - 香港中醫藥論壇, 2019.
Hao D., 瞻前顧後——肩部筋傷的整體治療思路, 香港中醫骨傷科學術 年會2018, 2018.
Hao D., 拗柴的常見并發症, 中醫藥轉換醫學講座系列, 2019.
Hao D., 拗柴的常見并發症, 第三屆香港骨傷科流 行病中醫診治療法論 壇, 2018.
Hao D., 中醫傳統運動與精神健康, 心源, 香港, 明愛樂晴軒, 2018, 9: 3-5.


Researcher : He Y
List of Research Outputs

Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.


Researcher : Hu KY
Project Title:The 6th World Congress of Chinese Medicine 2009 The International Spread Characteristics of Traditional Chinese Medicine
Investigator(s):Hu KY
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2009




Researcher : KUMAR M
List of Research Outputs

Zhao J., ZHU M., KUMAR M., NGO F.Y., Li Y., Lao L. and Rong J., A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases, CNS & Neurological Disorders - Drug Targets. 2019, 18: 103-114.


Researcher : LAM KH
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.


Researcher : LAM WL
List of Research Outputs

Chen H., Yang C., NING Z., LAM W.L., ZHAO Y., Yeung W.F., Ng B.F.L., Ziea E.T.C. and Lao L., A Guideline for Randomized Controlled Trials of Acupuncture, The American Journal of Chinese Medicine. 2019, 1-18.


Researcher : LI L
List of Research Outputs

Feng Y., LI L., LI S. and Wang N., Study Liver Diseases, TCM In Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Li L., Efficacy Observation on Tian Jiu Therapy for Asthma, 11th Taipei Traditional Chinese Medicine International Forum 2019. Taipei, Taiwan.
Li L., Herbal Juice Therapy in Chinese Medicine, 17th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Kuching, Sarawak, Malaysia, 2018.
Lo K.C. and Li L., "Pushing NeiBaGua" and the Thought of ZhouYi Study, 11th Taipei Traditional Chinese Medicine International Forum 2019. Taipei, Taiwan.
Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.


Researcher : LI S
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
Feng Y., LI L., LI S. and Wang N., Study Liver Diseases, TCM In Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.
LI S., Wang N., Tan H.Y.H., HONG M., Yuen R.M.F., Li H. and Feng Y., Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage, Frontiers in immunology. 2018, 9: 1524.
XU Y., Tan H.Y.H., LI S., Wang N. and Feng Y., Panax notoginseng for Inflammation-Related Chronic Diseases: A Review on the Modulations of Multiple Pathways, The American journal of Chinese medicine. 2018, 46: 971-996.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : LI W
List of Research Outputs

FENG J., Chen X., Lu S., LI W., Wang Q., Xu A. and Shen J., Naringin attenuates cerebral ischemia-reperfusion injury through inhibiting peroxynitrite-mediated mitophagy activation, Molecular Neurobiology . 2018, 2018.
LI W., WU H., GAO C., Yang D., Su W., Yang D. and Shen J., Radix Rehmanniae Extract Ameliorates Experimental Autoimmune Encephalomyelitis by Suppressing Macrophage-derived Nitrative Damage., Frontiers in Physiology . 2018, 9: 864.


Researcher : LIU J
List of Research Outputs

LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.


Researcher : LUO D
List of Research Outputs

CHENG Y., YANG C., LUO D., Li X.C., Le X.C. and Rong J., N-Propargyl Caffeamide Skews Macrophages Towards a Resolving M2-Like Phenotype Against Myocardial Ischemic Injury via Activating Nrf2/HO-1 Pathway and Inhibiting NF-ĸB Pathway, Cellular Physiology and Biochemistry. 2018, 47: 2544-2557.
ZHAO Y., LUO D., NING Z., Rong J. and Lao L., Electro-Acupuncture Ameliorated MPTP-Induced Parkinsonism in Mice via TrkB Neurotrophic Signaling, Frontiers in Neuroscience. 2019, 13.


Researcher : Lao L
Project Title:2014 International Research Congress on Integrative Medicine and Health; Acupuncture and Complementary Medicine in Pain Management/Acupuncture and Mindfulness-Based Stress Reduction among Female Child Abuse Survivors: A Randomized Waitlist-Controlled Pilot Study
Investigator(s):Lao L
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2014


Project Title:Combined Electroacupuncture and Auricular Acupuncture for Postoperative Pain after Abdominal Surgery for Gynecological Diseases: A Randomized Sham-controlled Trial
Investigator(s):Lao L, Ngan HYS, Chen H, Cheung CW, Yeung WF, Chan KKL, Wong CKH, Jiang F
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2016


Project Title:A randomized, wait-list controlled trial of self-administered acupressure for symptom management among Chinese family caregivers with caregiver stress
Investigator(s):Lao L, Lum TYS, Wang XMA, Cheung ST, Zhang Z, Tiwari AFY
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2016


Project Title:Development of a Novel Auriculotherapy Device for Pain Management
Investigator(s):Lao L, Cheung CW, Chen H, Yang C
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:06/2018


Project Title:Antinociceptive effects of electroacupuncture on persistent inflammatory pain via spinal adiponectin-dependent pathway to suppress neuroinflammation and central sensitization in animal models
Investigator(s):Lao L, Chen H
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:07/2018
Completion Date:11/2018


Project Title:World Acupuncture Day 2018; Efficacy and Safety of Acupuncture Treatment on Primary Insomnia: A Randomized Controlled Trial
Investigator(s):Lao L
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2018
Completion Date:11/2018


List of Research Outputs

Chen H., Yang C., NING Z., LAM W.L., ZHAO Y., Yeung W.F., Ng B.F.L., Ziea E.T.C. and Lao L., A Guideline for Randomized Controlled Trials of Acupuncture, The American Journal of Chinese Medicine. 2019, 1-18.
Chen H., Yang C. and Lao L., Acupuncture for Women Undergoing In Vitro Fertilization, JAMA. 2018, 320: 1385.
Chen Y., Xiang X., Wu J., Lao L. and Chen H., Acupressure for labor pain management: a systemic review and meta-analysis of randomized controlled trials, the Fourth American TCM Congress. 2018.
Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019.
Cheung S.T., Tiwari A.F.Y., Yeung W.F. and Lao L., 1. Cheung DST, Tiwari A, Yeung WF, Lao LL: Preliminary Results of a Randomized Controlled Trial of Self-administered Acupressure for Symptom Management among Caregivers with Caregiver Stress., Acupuncture Research, Health Care Policy, & Community Health - Closing the Loop. 2019.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.
LIU X., HU J., Lao L., Chen H. and Wu J., The efficacy of anti-hypertension by self-stimulation on channel-skin regions of hands and feet for Hypertension：A pilot study, the Fourth American TCM Congress, Seattle, USA, 4-5/08/2018, hosted by TCM American Alumni Association. 2018.
Lao L. and Yang C., Difficulties and Challenges Clinical Acupuncture Trials Are Facing, Evaluation of Acupuncture. Peter Lang D, 2018.
Lao L. and Yang C., Evidence-Based Acupuncture and Mechanistic Studies of Acupuncture , Evaluation of Acupuncture. Peter Lang D, 2018.
Lao L. and Chen H., How to Design, Conduct and Report a Randomized Controlled Trial on Acupuncture, Professional English for Scientific Research in Traditional Chinese Medicine. Beijing, People's Medical Publishing House, 2018, 230-245.
Leung K.K., Tsang K., Ting H., Ma C.H., Lun K.K., Ho T., Chu C.Y.T., Chan H.Y.F., Chou L., Wen G.Y., Ng J.T., Lau A., Jiang F., Ng B.F.L., Ziea E., Lao L., Fok M.W.M., Fang C.X. and Chen H., Sinew acupuncture for de Quervain's Tenosynovitis (dQt): a randomised controlled trial, Advances in Integrative Medicine. 2019, 6: S84.
Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.
So T.H., Chan S.K., Lee V.H.F., Chen B.Z., Kong F.P. and Lao L., Chinese Medicine in Cancer Treatment -How is it Practiced in the East and the West?, Clinical Oncology . 2019, 31: 578–588.
Tsang K.W., Leung C.T., Au Yeung Y., Lao L., Wu J. and Chen H., Acupuncture for diabetic peripheral neuropathy: a systematic review of randomized controlled trials, The Fourth American TCM Congress. 2018.
Yang C. and Lao L., Emerging Applications of Metabolomics in Traditional Chinese Medicine Treating Hypertension: Biomarkers, Pathways and More, Frontiers in Pharmacology. 2019, 10.
Yeung W.F., Chung K.F., Zhang Z., Zhang S.P., Chan W.C., Ng R.M.K., Chan L.W.C., Ho L.M., Yu B.Y.M., Chan J.C.S., Lau N.C.L. and Lao L., Electroacupuncture for tapering off long-term benzodiazepine use: A randomized controlled trial, Journal of Psychiatric Research. 2018.
You Y., Luo Q., WU W., Zhang J., Zhu H.J., Lao L., Lan H.Y., Chen H. and Cheng Y., Petchiether A attenuates obstructive nephropathy by suppressing TGF-β/Smad3 and NF-κB signalling, Journal of Cellular and Molecular Medicine. 2019.
ZHANG L., NG T.B., Lam J.K.W., WANG S., Lao L., Zhang Y. and Sze C.W.S., Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers, Current Protein & Peptide Science. 2019, 20: 277-284.
ZHAO Y., LUO D., NING Z., Rong J. and Lao L., Electro-Acupuncture Ameliorated MPTP-Induced Parkinsonism in Mice via TrkB Neurotrophic Signaling, Frontiers in Neuroscience. 2019, 13.
Zhao J., ZHU M., KUMAR M., NGO F.Y., Li Y., Lao L. and Rong J., A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases, CNS & Neurological Disorders - Drug Targets. 2019, 18: 103-114.


Researcher : Li L
Project Title:Efficacy Observation on Tian Jiu Therapy for Asthma
Investigator(s):Li L, Lao L, Cherny SS
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


Project Title:Effects of Massage methodology on the constipaion problem among the pre-school aged children with behavioral problem in subvented services in Yan Chai Hospital Social Services Department
Investigator(s):Li L, Lo KC, Chau PH
Department:School of Chinese Medicine
Source(s) of Funding:Yan Chai Hospital Board
Start Date:09/2017


List of Research Outputs

Feng Y., LI L., LI S. and Wang N., Study Liver Diseases, TCM In Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Li L., Efficacy Observation on Tian Jiu Therapy for Asthma, 11th Taipei Traditional Chinese Medicine International Forum 2019. Taipei, Taiwan.
Li L., Herbal Juice Therapy in Chinese Medicine, 17th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Kuching, Sarawak, Malaysia, 2018.
Lo K.C. and Li L., "Pushing NeiBaGua" and the Thought of ZhouYi Study, 11th Taipei Traditional Chinese Medicine International Forum 2019. Taipei, Taiwan.
Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.


Researcher : Li S
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
Feng Y., LI L., LI S. and Wang N., Study Liver Diseases, TCM In Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.
LI S., Wang N., Tan H.Y.H., HONG M., Yuen R.M.F., Li H. and Feng Y., Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage, Frontiers in immunology. 2018, 9: 1524.
XU Y., Tan H.Y.H., LI S., Wang N. and Feng Y., Panax notoginseng for Inflammation-Related Chronic Diseases: A Review on the Modulations of Multiple Pathways, The American journal of Chinese medicine. 2018, 46: 971-996.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : Li S
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
Feng Y., LI L., LI S. and Wang N., Study Liver Diseases, TCM In Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.
LI S., Wang N., Tan H.Y.H., HONG M., Yuen R.M.F., Li H. and Feng Y., Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage, Frontiers in immunology. 2018, 9: 1524.
XU Y., Tan H.Y.H., LI S., Wang N. and Feng Y., Panax notoginseng for Inflammation-Related Chronic Diseases: A Review on the Modulations of Multiple Pathways, The American journal of Chinese medicine. 2018, 46: 971-996.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : Li Y
List of Research Outputs

Zhao J., ZHU M., KUMAR M., NGO F.Y., Li Y., Lao L. and Rong J., A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases, CNS & Neurological Disorders - Drug Targets. 2019, 18: 103-114.


Researcher : Liang MQ
List of Research Outputs

Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.


Researcher : Liu C
Project Title:6th Annual Rocky Mountain Bioinformatics Conference CADEG, a Set of Software Tools for High Resolution Identification of Potential Chromosomal Abnormalities
Investigator(s):Liu C
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2008




Researcher : Lo KC
List of Research Outputs

Lo K.C. and Li L., "Pushing NeiBaGua" and the Thought of ZhouYi Study, 11th Taipei Traditional Chinese Medicine International Forum 2019. Taipei, Taiwan.
Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.


Researcher : Lo YLC
List of Research Outputs

Lo K.C., Li L., Lao L., He Y., Choi Y.M., Liang M.Q., Lo Y.L.C., Chan W.C.C., Shi H.F. and Tse W.H., Efficacy Observation on Sanfu Tianjiu Therapy for Asthma among Adults and Elderly, 17th CGCM. 2018.


Researcher : Meng W
List of Research Outputs

Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019.


Researcher : NGO FY
List of Research Outputs

Zhao J., ZHU M., KUMAR M., NGO F.Y., Li Y., Lao L. and Rong J., A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases, CNS & Neurological Disorders - Drug Targets. 2019, 18: 103-114.


Researcher : NING Z
List of Research Outputs

Chen H., Yang C., NING Z., LAM W.L., ZHAO Y., Yeung W.F., Ng B.F.L., Ziea E.T.C. and Lao L., A Guideline for Randomized Controlled Trials of Acupuncture, The American Journal of Chinese Medicine. 2019, 1-18.
ZHAO Y., LUO D., NING Z., Rong J. and Lao L., Electro-Acupuncture Ameliorated MPTP-Induced Parkinsonism in Mice via TrkB Neurotrophic Signaling, Frontiers in Neuroscience. 2019, 13.


Researcher : PENG F
List of Research Outputs

YOU J., GAO F., PENG F., Tang H., LIU H. and Chen J., A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4, 2019.


Researcher : Rong J
Project Title:The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy
Investigator(s):Rong J
Department:LKS Medical Faculty
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2006


Project Title:Novel caffeic acid derivatives promote the phenotypic and functional switch of macrophages toward resolution of inflammation and cardiac regeneration after myocardial infarction
Investigator(s):Rong J, Li XC
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2015
Completion Date:10/2018


Project Title:ω-Alkynyl arachidonic acid induces anti-inflammatory M2 polarization of macrophages in acute myocardial infarction via regulating the cross-talk between PKM2, iNOS and HIF-1α
Investigator(s):Rong J, Feng Y, Xia Z, Li XC
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2017


Project Title:Plant-derived celastrol ameliorates metabolic dysfunctions, oxidative stress and inflammation in diet-induced obesity via disrupting the cross-talk between PKM2, HIF-1α and IL-1β
Investigator(s):Rong J, Xia Z, Li XC, Wang Y
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2018


Project Title:Chinese medicine celastrol inhibits atherosclerotic foam cell formation via reducing lipid accumulation and ameliorating ER stress in diet-induced obese mice
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2018


Project Title:the 43rd FEBS 2018 Congress; ω-Alkynyl arachidonic acid stimulates anti-inflammatory macrophage M2 polarization against acute myocardial infarction via regulating the PKM2, HIF-1α and iNOS pathways
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2018
Completion Date:07/2018


Project Title:Novel caffeic acid derivatives resolve inflammation and suppress fibrosis in myocardial infarction via covalently binding to PPAR-gamma
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2019


Project Title:Pharmacological induction of pro-resolving macrophages for suppressing cardiac fibrosis in experimental myocardial infarction
Investigator(s):Rong J, Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2019


List of Research Outputs

CHENG Y., YANG C., LUO D., Li X.C., Le X.C. and Rong J., N-Propargyl Caffeamide Skews Macrophages Towards a Resolving M2-Like Phenotype Against Myocardial Ischemic Injury via Activating Nrf2/HO-1 Pathway and Inhibiting NF-ĸB Pathway, Cellular Physiology and Biochemistry. 2018, 47: 2544-2557.
Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019.
Cheng Y. and Rong J., Pro-resolving lipid mediators as therapeutic leads for cardiovascular diseases, Expert Opinion on Therapeutic Targets. 2019, 23: 423-436.
Rong J., (E)-3-(3,4-dihydroxyphenyl)-N-(prop-2-yn-1-yl)acrylamide for Treatment of Neurodegenerative Diseases, U.S. Patent: US10259777 B2. April 16, 2019., 2019.
Rong J., Celastrol-loaded PEG-PCL nanomicelles for treating diet-induced obesity in mice, The 6th Nano Today Conference, June 16-20, 2019, Lisbon, Portugal. 2019.
Rong J., Covalent conjugation in the pharmacology of Chinese medicines, The 8th Annual Meeting for Chinese Medicines, April 10-12, 2019, Guilin, China.. 2019.
Rong J., Molecular mechanism underlies the anti-inflammatory and cardioprotective activities of arachidonic acid metabolites against acute myocardial infarction, Invited lecture, Hunan Normal University, May 8-9, 2019, Changsha, China., 2019.
Rong J., Molecular mechanism underlies the anti-inflammatory and cardioprotective activities of ω-alkynyl arachidonic acid against acute myocardial infarction, Invited lecture, The 4th LipidALL Symposium, Nov 9–12, 2018, Beijing, China.. 2018.
Rong J., New mechanisms underlying the anti-obesity effects of celastrol, Invited lecture, Beijing University of Traditional Chinese Medicine, November 12, 2018, Beijing, China., 2018.
Rong J., Targeting the Keap1-Nrf2 Pathway to Ameliorate Oxidative Stress and Inflammation, The 4th Global Chinese Symposium & The 8th Symposium for Cross- straits, Hong Kong and Macao on Free Radical Biology and Medicine, 2018.9. 21-24, Macau, China. 2018.
Rong J., The anti-obesity effects of Chinese medicine celastrol, The 10th PDY international Symposium, October 22, 2018, Hong Kong, China.. 2018.
ZHAO Y., LUO D., NING Z., Rong J. and Lao L., Electro-Acupuncture Ameliorated MPTP-Induced Parkinsonism in Mice via TrkB Neurotrophic Signaling, Frontiers in Neuroscience. 2019, 13.
Zhang Z., Ma X., Jia M.F., Li B.W., Rong J. and Yang X.B., Deposition of CdTe quantum dots on microfluidic paper chips for rapid fluorescence detection of pesticide 2,4-D, The Analyst. 2018, 144: 1282-1291.
Zhao J., ZHU M., KUMAR M., NGO F.Y., Li Y., Lao L. and Rong J., A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases, CNS & Neurological Disorders - Drug Targets. 2019, 18: 103-114.


Researcher : SHI D
List of Research Outputs

SHI D. and Zhang Z., Chemotherapy-induced cognitive impairment is associated with cytokine dysregulation and disruptions in neuroplasticity, Molecular neurobiology . 2018.


Researcher : Shen J
Project Title:Biochemical Society Meeting 679 University of Essex UK - Stress, Signalling and Control Reactive Oxygen Species Mediate Intracellular Cholesterol Accumulation via Modulating Caveolin-1 Pathway in Chinese Hamster Ovary Cells
Investigator(s):Shen J
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2003


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating neurogenesis under hypoxic and ischemic conditions
Investigator(s):Shen J, Yang D, Chen X
Department:School of Chinese Medicine
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2013


Project Title:Exploring HMGB1 signaling as molecular target in peroxynitrite-mediated blood brain barrier disruption and hemorrhage transformation in ischemia-reperfused brain with delayed thrombolytic therapy
Investigator(s):Shen J, Yang D, Chung SK
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2015
Completion Date:09/2018


Project Title:Elucidating Impacts of Reactive Nitrogen Species-mediated Excessive Mitophagy on Cerebral Ischemic-Reperfusion Injury and Exploring the Neuroprotective Mechanisms of Naringin for Inhibition of Excessive Mitophagy
Investigator(s):Shen J, Chen X
Department:School of Chinese Medicine
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2016


Project Title:Exploring Effects of Glycyrrhizin, an Active Compound from Glycyrrhizae Radix, on Attenuating Delayed Tissue-plasminogen Activator (t-PA) Treatment-induced Hemorrhagic Transformation in Ischemic Stroke
Investigator(s):Shen J, Chen X, Fung ML, Chen H
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2016
Completion Date:06/2019


Project Title:Evaluating the neuroprotective effect and safety of An-Gong-Niu-Huang Wan and its ingredients in ischemic stroke
Investigator(s):Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Matching Grant for Joint Research
Start Date:06/2016


Project Title:Exploring Molecular Targets for Drug Discovery to Preventing Hyperglycemia-mediated Hemorrhagic transformation in Ischemic Stroke: Sodium Danshensu (SDSS) as an Example
Investigator(s):Shen J, Siu DCW, Chung SK
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2017


Project Title:Elucidating the roles of caveolin-1, a major component of mitochondria-associated-membrane, in regulating adult hippocampal neurogenesis and ageing
Investigator(s):Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2019


List of Research Outputs

Chen H. and Shen J., Angong Niuhuang Pill (ANP) attenuated hemorrhagic transformation and improved neurological outcomes in ischemic stroke with delayed tissue plasminogen activator (t-PA) treatment, possibly through inhibiting peroxynitrite-MMP9 signaling pathway, The 4th global Chinese Symposium & The 8th Symposium for cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Chen H. and Shen J., Angong Niuhuang Pill Prevents Hemorrhagic Transformation and promotes Outcome in Ischemic Stroke with Delayed t-PA treatment, possibly through Inhibiting Peroxynitrite-Mediated HMGB1/MMP-9 Signaling Cascades, 14th International Symposium on Healthy Aging. 2019.
Chen H. and Shen J., Best Presentation award, The 4th Global Chinese Symposium & The 8th Symposium for Cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Chen H. and Shen J., Chinese Herbal Medicine: A Great Opportunity for Reducing Thrombolysis-mediated Hemorrhagic Transformation in Ischemic Stroke Treatment, 6 th Macau Symposium on Biomedical Sciences 2019. 2019.
Chen H., Chen X., Luo Y. and Shen J., Potential molecular targets of peroxynitrite in mediating blood–brain barrier damage and haemorrhagic transformation in acute ischaemic stroke with delayed tissue plasminogen activator treatment, Free Radical Research. 2018, 1-20.
Chen X., Chen H., Peng C. and Shen J., Active compounds and molecular targets of Chinese herbal medicine for neurogenesis in stroke treatment: Implication for cross talk between Traditional Chinese Medicine and Biomedical Sciences, World Journal of Traditional Chinese Medicine. 2019, 5: 104.
Chen X., WU H., Chen H., Wang Q., Xie X. and Shen J., Astragaloside VI Promotes Neural Stem Cell Proliferation and Enhances Neurological Function Recovery in Transient Cerebral Ischemic Injury via Activating EGFR/MAPK Signaling Cascades, Molecular Neurobiology. 2018, 56(4): 3053-3067.
Deng R., Law H.Y., Shen J. and Chan G.C.F., Mini Review: Application of Human Mesenchymal Stem Cells in Gene and Stem Cells Therapy Era, In: G. Almeida-Porada; D.S. Krause, Current Stem Cell Reports. Springer International Publishing, 2018, 4: 327-337.
FENG J., Chen X. and Shen J., Inhibition of peroxynitrite-induced mitophagy activation attenuates cerebral ischemia-reperfusion injury, Molecular Neurobiology. 2018, 55: 6369-6386.
FENG J., Chen X., Lu S., LI W., Wang Q., Xu A. and Shen J., Naringin attenuates cerebral ischemia-reperfusion injury through inhibiting peroxynitrite-mediated mitophagy activation, Molecular Neurobiology . 2018, 2018.
Gao C., Chen X., Xu A., Cheng K.Y. and Shen J., Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor, Molecular Neurobiology. 2018, 55: 5537-5547.
LI W., WU H., GAO C., Yang D., Su W., Yang D. and Shen J., Radix Rehmanniae Extract Ameliorates Experimental Autoimmune Encephalomyelitis by Suppressing Macrophage-derived Nitrative Damage., Frontiers in Physiology . 2018, 9: 864.
Lin R., Duan Z., Sun H., Fung M.L., Chen H., Wang J., Lau C.F., Yang D., Liu Y., Ni Y., Wang Z., Cui J., Wu W., Yung W.H., Chan Y.S., Lo A.C.Y., Xia J., Shen J. and Huang J., Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity, iScience. 2019, 13: 82-97.
Luo Y.X., Wang X.Y., Huang Y.J., Fang S.H., Wu J., Zhang Y.B., Xiong T.Q., Yang C., Shen J., Sang C.L., Wang Q. and Fang J.S., Systems pharmacology-based investigation of Sanwei Ganjiang Prescription: related mechanisms in liver injury, Chinese Journal of Natural Medicines. 2018, 16: 756-765.
Mo Y.S., Xu E.J., Wei R.R., Le B.L., Li D.L., Chen Y.G., Li X.T., Feng S.H., Shen J., Yang C. and Wang Q., Bushen-Yizhi Formula Alleviates Neuroinflammation via Inhibiting NLRP3 Inflammasome Activation in a Mouse Model of Parkinson’s Disease. , Evidence-Based Complementary and Alternative Medicine. 2018, 2018: Article ID 3571604.
Shen J., Astragaloside VI promotes neural stem cell proliferation and enhances neurological function recovery in transient cerebral ischemic brain via activating EGFR/MAPK signaling cascades, 17th CGCM Meeting, Kuching Sarawak, Malaysia, August 8-10, 2018 . 2018.
Shen J., Naringin Attenuates Cerebral Ischemia-Reperfusion Injury Through Inhibiting Peroxynitrite-Mediated Mitophagy Activation., 17th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Malaysian Institute of Pharmaceuticals & Nutraceuticals (IPharm), National Institutes of Biotechnology Malaysia (NIBM) Kuching, Sarawak, 8th- 10th August 2018 . 2018.
Shen J., Oxidative Stress and Antioxidant: What We Should Do for Brain Damage and Brain Repair and its Implication in Stroke Treatment, Invited Speaker, 18th World COngress of Basic and Clinical Pharmacology, Kyoto, Japan July 1-6th, 2018. 2018.
Shen J., Oxidative stress and antioxidant: What we should do for brain damage and brain repair and implication for Chinese Medicine in stroke treatment, 18th World COngress of Basic and CLinical Pharmacology, July 1-6, 2018, Kyoto, Japan. 2018.
Shen J., FENG J. and Chen H., Peroxynitrite-mediated mitophagy could be a crucial therapeutic target for reducing cerebral ischemia–reperfusion injury, The 4th Global Chinese Symposium & the 8th Symposium for Cross-straits, Hong Kong and Macao on Free Radical Biology and Medicine. 2018.
Shen J., FENG J. and Chen H., Peroxynitrite‑mediated mitophagy could be a crucial therapeutic target for reducing cerebral ischemia–reperfusion injury, 4th Global Chinese Symposium and the 8th Symposium for cross-straits, Hong Kong and Macao on free radical biology and medicine. 2018, 13: 56.
Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.


Researcher : Shi J
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.


Researcher : Su J
List of Research Outputs

Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019.


Researcher : Sze CW
Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS, Zhang Y, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:12/2009


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2010


Project Title:Study of target-based Chinese herbal medicine in suppression of aberrant cryptic foci: implication of colon cancer prevention
Investigator(s):Sze CWS, Lao L, Zhang Y, Xu K
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2017


Project Title:Research and Development of the Chinese Medicine Formula ZB and Its Bioactive Compounds as Adjuvant Therapy for Colon Cancer and for Alleviation of Chemotherapy-Induced Osteoporosis using Network and Systems Pharmacological Approaches
Investigator(s):Sze CWS, Lao L, Zhang Y, Leung GPH, Lam JKW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:10/2017


List of Research Outputs



Researcher : Sze CWS
Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS, Zhang Y, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:12/2009


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2010


Project Title:Study of target-based Chinese herbal medicine in suppression of aberrant cryptic foci: implication of colon cancer prevention
Investigator(s):Sze CWS, Lao L, Zhang Y, Xu K
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2017


Project Title:Research and Development of the Chinese Medicine Formula ZB and Its Bioactive Compounds as Adjuvant Therapy for Colon Cancer and for Alleviation of Chemotherapy-Induced Osteoporosis using Network and Systems Pharmacological Approaches
Investigator(s):Sze CWS, Lao L, Zhang Y, Leung GPH, Lam JKW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:10/2017


List of Research Outputs

ZHANG L., NG T.B., Lam J.K.W., WANG S., Lao L., Zhang Y. and Sze C.W.S., Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers, Current Protein & Peptide Science. 2019, 20: 277-284.


Researcher : Tan HY
List of Research Outputs



Researcher : Tan HYH
List of Research Outputs

CHEN F., Wang N., Tan H.Y.H., GUO W., ZHANG C. and Feng Y., The functional roles of exosomes-derived long non-coding RNA in human cancer, Cancer Biology & Therapy. 2019, 1-10.
Feng Y., Tan H.Y.H., Wang N. and Wang L., Endangered species in Chinese medicine: the example of bear bile, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.
Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.
LI S., Wang N., Tan H.Y.H., HONG M., Yuen R.M.F., Li H. and Feng Y., Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage, Frontiers in immunology. 2018, 9: 1524.
Qu Y., Dou B., Tan H.Y.H., Feng Y., Wang N. and Wang D., Tumor microenvironment-driven non-cell-autonomous resistance to antineoplastic treatment, Molecular Cancer. 2019, 18.
Tan H.Y.H., Wang N. and Feng Y., Genetical inhibition of IRE1α in macrophages suppresses hepatocellular carcinoma growth, 25th Biennial Congress of the European Association for Cancer Research. 2018.
Tan H.Y.H., Wang N., Lam W., GUO W., Feng Y. and Cheng Y.C., Targeting tumour microenvironment by tyrosine kinase inhibitor, Molecular Cancer. 2018, 17.
Tan H.Y.H., Wang N. and Feng Y., The anti-tumour effect of mangiferin from Mangifera indica Linn. (Anacardiaceae) leaves on human hepatocellular carcinoma, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.
Wang N., ZHANG C., Tan H.Y.H. and Feng Y., Insulin accelerates progression of diabetic retinopathy through activating HIF-1α/VEGF pathway in retinal endothelial cells, 7th Seoul International Congress of Endocrinology and Metabolism. 2019.
Wang N., Tan H.Y.H., Feng Y.G., ZHANG C., CHEN F. and Feng Y., microRNA-23a in Human Cancer: Its Roles, Mechanisms and Therapeutic Relevance, Cancers. 2018, 11: 7.
XU Y., Tan H.Y.H., LI S., Wang N. and Feng Y., Panax notoginseng for Inflammation-Related Chronic Diseases: A Review on the Modulations of Multiple Pathways, The American journal of Chinese medicine. 2018, 46: 971-996.
Xue X.T., Tan H.Y.H., Teng S.T., Chan Y.T., Wang D.W. and Wang N., The Role of AMP-Activated Protein Kinase as a Potential Target of Treatment of Hepatocellular Carcinoma, Cancers. 2019, 11: 647.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : Tang H
List of Research Outputs

YOU J., GAO F., PENG F., Tang H., LIU H. and Chen J., A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4, 2019.


Researcher : Tong Y
Project Title:A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials
Investigator(s):Tong Y, Shen J, Zhong L, Diu CK
Department:School of Chinese Medicine
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:09/2009


List of Research Outputs

Chen H. and Tong Y., Systematic Reviews and Meta-Analyses, Professional English for Scientific Research in Traditional Chinese Medicine. Beijing, People's Medical Publishing House, 2018, 1-28.


Researcher : Tsoi B
Project Title:World Conference On Neurology: Neuroscience & Brain Disorders; Neuroprotective effects and toxicological study of Angong Niuhuang Wan against ischemia-reperfusion brain injury in rats
Investigator(s):Tsoi B
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2019
Completion Date:06/2019


List of Research Outputs

Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.


Researcher : WANG N
List of Research Outputs

CHEN F., Wang N., Tan H.Y.H., GUO W., ZHANG C. and Feng Y., The functional roles of exosomes-derived long non-coding RNA in human cancer, Cancer Biology & Therapy. 2019, 1-10.
Feng Y., Tan H.Y.H., Wang N. and Wang L., Endangered species in Chinese medicine: the example of bear bile, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.
Feng Y., LI L., LI S. and Wang N., Study Liver Diseases, TCM In Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.
LI S., Wang N., Tan H.Y.H., HONG M., Yuen R.M.F., Li H. and Feng Y., Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage, Frontiers in immunology. 2018, 9: 1524.
Liu Y., Yang A., Qu Y., Wang Z., Zhang Y., Liu Y., Wang N., Teng L. and Wang D., Ameliorative effects of Antrodia cinnamomea polysaccharides against cyclophosphamide-induced immunosuppression related to Nrf2/HO-1 signaling in BALB/c mice, International Journal of Biological Macromolecules. 2018, 116: 8-15.
Qu Y., Dou B., Tan H.Y.H., Feng Y., Wang N. and Wang D., Tumor microenvironment-driven non-cell-autonomous resistance to antineoplastic treatment, Molecular Cancer. 2019, 18.
Tan H.Y.H., Wang N. and Feng Y., Genetical inhibition of IRE1α in macrophages suppresses hepatocellular carcinoma growth, 25th Biennial Congress of the European Association for Cancer Research. 2018.
Tan H.Y.H., Wang N., Lam W., GUO W., Feng Y. and Cheng Y.C., Targeting tumour microenvironment by tyrosine kinase inhibitor, Molecular Cancer. 2018, 17.
Tan H.Y.H., Wang N. and Feng Y., The anti-tumour effect of mangiferin from Mangifera indica Linn. (Anacardiaceae) leaves on human hepatocellular carcinoma, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.
WANG N., zhang X., Chen J., xiang D. and wang Z.H.I., 中醫藥干預惡性腫瘤轉移新模式——靶向調控預轉移, 環球中醫藥, 2019.
Wang N., ZHANG C., Tan H.Y.H. and Feng Y., Insulin accelerates progression of diabetic retinopathy through activating HIF-1α/VEGF pathway in retinal endothelial cells, 7th Seoul International Congress of Endocrinology and Metabolism. 2019.
Wang N. and Feng Y., Quality Control Of Chinese Herbal Medicine, Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Wang N., Travel Grant on the selected poster presentation on SICEM 2019, 2019.
Wang N., Tan H.Y.H., Feng Y.G., ZHANG C., CHEN F. and Feng Y., microRNA-23a in Human Cancer: Its Roles, Mechanisms and Therapeutic Relevance, Cancers. 2018, 11: 7.
XU Y., Tan H.Y.H., LI S., Wang N. and Feng Y., Panax notoginseng for Inflammation-Related Chronic Diseases: A Review on the Modulations of Multiple Pathways, The American journal of Chinese medicine. 2018, 46: 971-996.
Xue X.T., Tan H.Y.H., Teng S.T., Chan Y.T., Wang D.W. and Wang N., The Role of AMP-Activated Protein Kinase as a Potential Target of Treatment of Hepatocellular Carcinoma, Cancers. 2019, 11: 647.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : WANG S
List of Research Outputs

Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.
ZHANG L., NG T.B., Lam J.K.W., WANG S., Lao L., Zhang Y. and Sze C.W.S., Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers, Current Protein & Peptide Science. 2019, 20: 277-284.


Researcher : WU H
List of Research Outputs

Chen X., WU H., Chen H., Wang Q., Xie X. and Shen J., Astragaloside VI Promotes Neural Stem Cell Proliferation and Enhances Neurological Function Recovery in Transient Cerebral Ischemic Injury via Activating EGFR/MAPK Signaling Cascades, Molecular Neurobiology. 2018, 56(4): 3053-3067.
LI W., WU H., GAO C., Yang D., Su W., Yang D. and Shen J., Radix Rehmanniae Extract Ameliorates Experimental Autoimmune Encephalomyelitis by Suppressing Macrophage-derived Nitrative Damage., Frontiers in Physiology . 2018, 9: 864.


Researcher : WU W
List of Research Outputs

WU W., Wang J., Chen H. and Meng X.M., 7-hydroxycoumarin protects against acute kidney injury by inhibiting necroptosis and promoting Sox-9-mediated cell proliferation, ISN World Congress of Nephrology 2019.
WU W., Huang X.R., You Y., Chen H. and Lan H.Y., Latent TGF-β protects against diabetic kidney disease via GARP-latent TGF-β mediated anti-inflammation, ISN World Congress of Nephrology 2019.
You Y., Luo Q., WU W., Zhang J., Zhu H.J., Lao L., Lan H.Y., Chen H. and Cheng Y., Petchiether A attenuates obstructive nephropathy by suppressing TGF-β/Smad3 and NF-κB signalling, Journal of Cellular and Molecular Medicine. 2019.
You Y., Huang X.R., WU W., Chen H. and Lan H.Y., Restoration of PGC-1α activity by Smad3 deficiency protects against CRP-exacerbated kidney injury after unilateral ureteral obstruction, ISN World Congress of Nephrology 2019.


Researcher : Wang L
List of Research Outputs

Feng Y., Tan H.Y.H., Wang N. and Wang L., Endangered species in Chinese medicine: the example of bear bile, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.


Researcher : Wang MN
Project Title:Hepatic SBP2 expression alleviates acute and chronic liver injury caused by alcohol beverage via suppressing inflammasome activation in hepatocytes
Investigator(s):Wang N, Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2017
Completion Date:12/2018


Project Title:Investigation on the effect of berberine on improvement of diabetic retinopathy in insulin-treated diabetic mellitus
Investigator(s):Wang N, Feng Y, Chen H
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2018


Project Title:25th Biennial Congress of the European Association for Cancer Research; The role of autophagy-related protein 9B in liver carcinogenesis
Investigator(s):Wang N
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2018
Completion Date:07/2018


Project Title:The 7th Seoul International Congress of Endocrinology and Metabolism; INSULIN ACCELERATES PROGRESSION OF DIABETIC RETINOPATHY THROUGH ACTIVATING HIF-1Α/VEGF PATHWAY IN RETINAL ENDOTHELIAL CELLS
Investigator(s):Wang N
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2019
Completion Date:04/2019


List of Research Outputs



Researcher : Wang N
Project Title:Hepatic SBP2 expression alleviates acute and chronic liver injury caused by alcohol beverage via suppressing inflammasome activation in hepatocytes
Investigator(s):Wang N, Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2017
Completion Date:12/2018


Project Title:Investigation on the effect of berberine on improvement of diabetic retinopathy in insulin-treated diabetic mellitus
Investigator(s):Wang N, Feng Y, Chen H
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2018


Project Title:25th Biennial Congress of the European Association for Cancer Research; The role of autophagy-related protein 9B in liver carcinogenesis
Investigator(s):Wang N
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2018
Completion Date:07/2018


Project Title:The 7th Seoul International Congress of Endocrinology and Metabolism; INSULIN ACCELERATES PROGRESSION OF DIABETIC RETINOPATHY THROUGH ACTIVATING HIF-1Α/VEGF PATHWAY IN RETINAL ENDOTHELIAL CELLS
Investigator(s):Wang N
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2019
Completion Date:04/2019


List of Research Outputs

CHEN F., Wang N., Tan H.Y.H., GUO W., ZHANG C. and Feng Y., The functional roles of exosomes-derived long non-coding RNA in human cancer, Cancer Biology & Therapy. 2019, 1-10.
Feng Y., Tan H.Y.H., Wang N. and Wang L., Endangered species in Chinese medicine: the example of bear bile, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.
Feng Y., LI L., LI S. and Wang N., Study Liver Diseases, TCM In Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Fu B., Wang N., Tan H.Y.H., Li S., Cheung F. and Feng Y., Multi-Component Herbal Products in the Prevention and Treatment of Chemotherapy-Associated Toxicity and Side Effects: A Review on Experimental and Clinical Evidences, Frontiers in Pharmacology. 2018, 9.
LI S., Wang N., Tan H.Y.H., HONG M., Yuen R.M.F., Li H. and Feng Y., Expansion of Granulocytic, Myeloid-Derived Suppressor Cells in Response to Ethanol-Induced Acute Liver Damage, Frontiers in immunology. 2018, 9: 1524.
Liu Y., Yang A., Qu Y., Wang Z., Zhang Y., Liu Y., Wang N., Teng L. and Wang D., Ameliorative effects of Antrodia cinnamomea polysaccharides against cyclophosphamide-induced immunosuppression related to Nrf2/HO-1 signaling in BALB/c mice, International Journal of Biological Macromolecules. 2018, 116: 8-15.
Qu Y., Dou B., Tan H.Y.H., Feng Y., Wang N. and Wang D., Tumor microenvironment-driven non-cell-autonomous resistance to antineoplastic treatment, Molecular Cancer. 2019, 18.
Tan H.Y.H., Wang N. and Feng Y., Genetical inhibition of IRE1α in macrophages suppresses hepatocellular carcinoma growth, 25th Biennial Congress of the European Association for Cancer Research. 2018.
Tan H.Y.H., Wang N., Lam W., GUO W., Feng Y. and Cheng Y.C., Targeting tumour microenvironment by tyrosine kinase inhibitor, Molecular Cancer. 2018, 17.
Tan H.Y.H., Wang N. and Feng Y., The anti-tumour effect of mangiferin from Mangifera indica Linn. (Anacardiaceae) leaves on human hepatocellular carcinoma, 17th Meeting of Consortium for Globalization of Chinese Medicine . 2018.
WANG N., zhang X., Chen J., xiang D. and wang Z.H.I., 中醫藥干預惡性腫瘤轉移新模式——靶向調控預轉移, 環球中醫藥, 2019.
Wang N., ZHANG C., Tan H.Y.H. and Feng Y., Insulin accelerates progression of diabetic retinopathy through activating HIF-1α/VEGF pathway in retinal endothelial cells, 7th Seoul International Congress of Endocrinology and Metabolism. 2019.
Wang N. and Feng Y., Quality Control Of Chinese Herbal Medicine, Professional English For Traditional Chinese Medical Research. Beijing, People's Medical Publishing House, 2018.
Wang N., Travel Grant on the selected poster presentation on SICEM 2019, 2019.
Wang N., Tan H.Y.H., Feng Y.G., ZHANG C., CHEN F. and Feng Y., microRNA-23a in Human Cancer: Its Roles, Mechanisms and Therapeutic Relevance, Cancers. 2018, 11: 7.
XU Y., Tan H.Y.H., LI S., Wang N. and Feng Y., Panax notoginseng for Inflammation-Related Chronic Diseases: A Review on the Modulations of Multiple Pathways, The American journal of Chinese medicine. 2018, 46: 971-996.
Xue X.T., Tan H.Y.H., Teng S.T., Chan Y.T., Wang D.W. and Wang N., The Role of AMP-Activated Protein Kinase as a Potential Target of Treatment of Hepatocellular Carcinoma, Cancers. 2019, 11: 647.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : Wang S
List of Research Outputs

Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.
ZHANG L., NG T.B., Lam J.K.W., WANG S., Lao L., Zhang Y. and Sze C.W.S., Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers, Current Protein & Peptide Science. 2019, 20: 277-284.


Researcher : Wong CWV
List of Research Outputs

Chan K.W., Kwong A.S.K., Chan G.C.W., Leung C.P.S., Yiu W.H., Lui S.L., Ip T.P., Cowling B.J., Wong W.L.D., LI B., LI Y., Feng Y., Chan L.Y.Y., Leung J.C.K., Tan K.C.B., Wong C.W.V., Lai K.N. and Tang S.C.W., Best Poster Award, Good Practice In Traditional Chinese Medicine Research Association. 2018.
Chan K.W., Kwong A.S.K., Chan G.C.W., Leung C.P.S., Yiu W.H., Lui S.L., Ip T.P., Cowling B.J., Wong W.L.D., LI B., LI Y., Feng Y., Chan Y.Y., Leung J.C.K., Tan K.C.B., Wong C.W.V., Lai K.N. and Tang S.C.W., Semi-individualised Chinese Medicine Treatment for Diabetic Kidney Disease – From users’ perspectives to SCHEMATIC trial interim result and potential mechanisms, Advances in Integrative Medicine (International Congress on Complementary Medicine Research). 2019, 6: S12.


Researcher : Wu J
Project Title:Anti-cystic hyperplasia of breast herbal medicine research
Investigator(s):Wu J, Chow LWC
Department:School of Chinese Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:05/2001


Project Title:Anti-prostatomegaly herbal medicine research
Investigator(s):Wu J, Leung SYL
Department:School of Chinese Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:06/2001




Researcher : Wu J
Project Title:Activation on Left Dorsolateral Prefrontal Cortex（LDPC）with Different Acupoint-Combinations for Depression：An fNIRS Study
Investigator(s):Wu J, Lao L, Chan WC, Zhu FF, Zhang Z, Yeung WF, Chen H
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research for New Staff
Start Date:06/2015


Project Title:The Fourth American Traditional Chinese Medicine Congress; The efficacy of antihypertension by self-stimulation on channel-skin regions of hands and feet for Hypertension：A pilot study
Investigator(s):Wu J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2018
Completion Date:08/2018


List of Research Outputs

Chen Y., Xiang X., Wu J., Lao L. and Chen H., Acupressure for labor pain management: a systemic review and meta-analysis of randomized controlled trials, the Fourth American TCM Congress. 2018.
LIU X., HU J., Lao L., Chen H. and Wu J., The efficacy of anti-hypertension by self-stimulation on channel-skin regions of hands and feet for Hypertension：A pilot study, the Fourth American TCM Congress, Seattle, USA, 4-5/08/2018, hosted by TCM American Alumni Association. 2018.
Tsang K.W., Leung C.T., Au Yeung Y., Lao L., Wu J. and Chen H., Acupuncture for diabetic peripheral neuropathy: a systematic review of randomized controlled trials, The Fourth American TCM Congress. 2018.


Researcher : XU Y
List of Research Outputs

XU Y., Tan H.Y.H., LI S., Wang N. and Feng Y., Panax notoginseng for Inflammation-Related Chronic Diseases: A Review on the Modulations of Multiple Pathways, The American journal of Chinese medicine. 2018, 46: 971-996.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : Xu K
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.


Researcher : YANG C
List of Research Outputs

CHENG Y., YANG C., LUO D., Li X.C., Le X.C. and Rong J., N-Propargyl Caffeamide Skews Macrophages Towards a Resolving M2-Like Phenotype Against Myocardial Ischemic Injury via Activating Nrf2/HO-1 Pathway and Inhibiting NF-ĸB Pathway, Cellular Physiology and Biochemistry. 2018, 47: 2544-2557.
Chen H., Yang C., NING Z., LAM W.L., ZHAO Y., Yeung W.F., Ng B.F.L., Ziea E.T.C. and Lao L., A Guideline for Randomized Controlled Trials of Acupuncture, The American Journal of Chinese Medicine. 2019, 1-18.
Chen H., Yang C. and Lao L., Acupuncture for Women Undergoing In Vitro Fertilization, JAMA. 2018, 320: 1385.
Lao L. and Yang C., Difficulties and Challenges Clinical Acupuncture Trials Are Facing, Evaluation of Acupuncture. Peter Lang D, 2018.
Lao L. and Yang C., Evidence-Based Acupuncture and Mechanistic Studies of Acupuncture , Evaluation of Acupuncture. Peter Lang D, 2018.
Yang C., Yu Z., Chen X., Guo Z., Deng S., Chen L., Wu Q. and Liang F., Active Acupoints Differ from Inactive Acupoints in Modulating Key Plasmatic Metabolites of Hypertension: A Targeted Metabolomics Study, Scientific Reports. 2018, 8.
Yang C., Acupuncture for Stable Angina Pectoris: A Systematic Review and Meta-Analysis, , SAR's 2019 International Research Conference. 2019.
Yang C., Acupuncture for Stable Angina Pectoris: A Systematic Review and Meta-Analysis, SAR's 2019 International Research Conference. 2019.
Yang C., Application of Metabolomics in Elucidating The Mechanism of Acupuncture Lowering Blood Pressure, 运用代谢组学技术研究针刺降压的效应机制, Academic Forum on the Future of Acupuncture 2018, organized by the China Association for Science and Technology. 中国科协2018年“海峡两岸 暨港澳青年科学家学术活 动月”活动-针灸的未来发展 学术论坛, 2018.
Yang C. and Lao L., Emerging Applications of Metabolomics in Traditional Chinese Medicine Treating Hypertension: Biomarkers, Pathways and More, Frontiers in Pharmacology. 2019, 10.
Yang J., Chen J., Yang C., Yu S., Ying Y., Liu G., Ren Y., Wright J. and Liang F., Acupuncture for hypertension, Cochrane Database of Systematic Reviews. Cochrane Library, 2018.
Yu .., Wen .., Xia .., Yang C., Lv .., Li .., Li .., Yang .., Hu .., Liang .. and Yang .., Acupoint herbal plaster for patients with primary dysmenorrhea: study protocol for a randomized controlled trial, Trials. 2018, 19.


Researcher : YOU J
List of Research Outputs

YOU J., GAO F., PENG F., Tang H., LIU H. and Chen J., A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4, 2019.
YOU J., LIU H. and Chen J., 陳建萍從肝論治乳腺癌思路與經驗, 2018.


Researcher : YUEN SC
List of Research Outputs

Tsoi B., Chen X., Gao C., Wang S., YUEN S.C., YANG D. and Shen J., Neuroprotective Effects and Hepatorenal Toxicity of Angong Niuhuang Wan Against Ischemia–Reperfusion Brain Injury in Rats, Frontiers in Pharmacology. 2019, 10: 593.


Researcher : Yang C
List of Research Outputs

CHENG Y., YANG C., LUO D., Li X.C., Le X.C. and Rong J., N-Propargyl Caffeamide Skews Macrophages Towards a Resolving M2-Like Phenotype Against Myocardial Ischemic Injury via Activating Nrf2/HO-1 Pathway and Inhibiting NF-ĸB Pathway, Cellular Physiology and Biochemistry. 2018, 47: 2544-2557.
Chen H., Yang C., NING Z., LAM W.L., ZHAO Y., Yeung W.F., Ng B.F.L., Ziea E.T.C. and Lao L., A Guideline for Randomized Controlled Trials of Acupuncture, The American Journal of Chinese Medicine. 2019, 1-18.
Chen H., Yang C. and Lao L., Acupuncture for Women Undergoing In Vitro Fertilization, JAMA. 2018, 320: 1385.
Lao L. and Yang C., Difficulties and Challenges Clinical Acupuncture Trials Are Facing, Evaluation of Acupuncture. Peter Lang D, 2018.
Lao L. and Yang C., Evidence-Based Acupuncture and Mechanistic Studies of Acupuncture , Evaluation of Acupuncture. Peter Lang D, 2018.
Yang C., Yu Z., Chen X., Guo Z., Deng S., Chen L., Wu Q. and Liang F., Active Acupoints Differ from Inactive Acupoints in Modulating Key Plasmatic Metabolites of Hypertension: A Targeted Metabolomics Study, Scientific Reports. 2018, 8.
Yang C., Acupuncture for Stable Angina Pectoris: A Systematic Review and Meta-Analysis, , SAR's 2019 International Research Conference. 2019.
Yang C., Acupuncture for Stable Angina Pectoris: A Systematic Review and Meta-Analysis, SAR's 2019 International Research Conference. 2019.
Yang C., Application of Metabolomics in Elucidating The Mechanism of Acupuncture Lowering Blood Pressure, 运用代谢组学技术研究针刺降压的效应机制, Academic Forum on the Future of Acupuncture 2018, organized by the China Association for Science and Technology. 中国科协2018年“海峡两岸 暨港澳青年科学家学术活 动月”活动-针灸的未来发展 学术论坛, 2018.
Yang C. and Lao L., Emerging Applications of Metabolomics in Traditional Chinese Medicine Treating Hypertension: Biomarkers, Pathways and More, Frontiers in Pharmacology. 2019, 10.
Yang J., Chen J., Yang C., Yu S., Ying Y., Liu G., Ren Y., Wright J. and Liang F., Acupuncture for hypertension, Cochrane Database of Systematic Reviews. Cochrane Library, 2018.
Yu .., Wen .., Xia .., Yang C., Lv .., Li .., Li .., Yang .., Hu .., Liang .. and Yang .., Acupoint herbal plaster for patients with primary dysmenorrhea: study protocol for a randomized controlled trial, Trials. 2018, 19.


Researcher : You Y
List of Research Outputs

WU W., Huang X.R., You Y., Chen H. and Lan H.Y., Latent TGF-β protects against diabetic kidney disease via GARP-latent TGF-β mediated anti-inflammation, ISN World Congress of Nephrology 2019.
You Y., Luo Q., WU W., Zhang J., Zhu H.J., Lao L., Lan H.Y., Chen H. and Cheng Y., Petchiether A attenuates obstructive nephropathy by suppressing TGF-β/Smad3 and NF-κB signalling, Journal of Cellular and Molecular Medicine. 2019.
You Y., Huang X.R., WU W., Chen H. and Lan H.Y., Restoration of PGC-1α activity by Smad3 deficiency protects against CRP-exacerbated kidney injury after unilateral ureteral obstruction, ISN World Congress of Nephrology 2019.


Researcher : ZHANG C
List of Research Outputs

CHEN F., Wang N., Tan H.Y.H., GUO W., ZHANG C. and Feng Y., The functional roles of exosomes-derived long non-coding RNA in human cancer, Cancer Biology & Therapy. 2019, 1-10.
Wang N., ZHANG C., Tan H.Y.H. and Feng Y., Insulin accelerates progression of diabetic retinopathy through activating HIF-1α/VEGF pathway in retinal endothelial cells, 7th Seoul International Congress of Endocrinology and Metabolism. 2019.
Wang N., Tan H.Y.H., Feng Y.G., ZHANG C., CHEN F. and Feng Y., microRNA-23a in Human Cancer: Its Roles, Mechanisms and Therapeutic Relevance, Cancers. 2018, 11: 7.
ZHANG C., Wang N., XU Y., Tan H.Y.H., LI S. and Feng Y., Molecular Mechanisms Involved in Oxidative Stress-Associated Liver Injury Induced by Chinese Herbal Medicine: An Experimental Evidence-Based Literature Review and Network Pharmacology Study, International Journal of Molecular Sciences. 2018, 19: 2745.


Researcher : ZHANG L
List of Research Outputs

ZHANG L., NG T.B., Lam J.K.W., WANG S., Lao L., Zhang Y. and Sze C.W.S., Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers, Current Protein & Peptide Science. 2019, 20: 277-284.


Researcher : ZHAO Y
List of Research Outputs

Chen H., Yang C., NING Z., LAM W.L., ZHAO Y., Yeung W.F., Ng B.F.L., Ziea E.T.C. and Lao L., A Guideline for Randomized Controlled Trials of Acupuncture, The American Journal of Chinese Medicine. 2019, 1-18.
ZHAO Y., LUO D., NING Z., Rong J. and Lao L., Electro-Acupuncture Ameliorated MPTP-Induced Parkinsonism in Mice via TrkB Neurotrophic Signaling, Frontiers in Neuroscience. 2019, 13.


Researcher : ZHU M
List of Research Outputs

Zhao J., ZHU M., KUMAR M., NGO F.Y., Li Y., Lao L. and Rong J., A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases, CNS & Neurological Disorders - Drug Targets. 2019, 18: 103-114.


Researcher : Zhang Y
Project Title:Discovery of characteristic chemical markers rapidly to detect sulfur-fumigated herbs
Investigator(s):Zhang Y, Sze CWS, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:04/2016


Project Title:BIT’s 5th Annual World Congress of Food and Nutrition-2016; Polysaccharides of Dendrobium officinale Induce Aquaporin 5 Translocation by Activating M3 Muscarinic Receptors
Investigator(s):Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2016


Project Title:The pharmacology mechanisms and safety study on the dendrobine granula jointed cisplatin to enhance the non-small cell lung cancer therapeutic efficacy
Investigator(s):Zhang Y, Lao L, Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017
Completion Date:03/2019


Project Title:The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):Zhang Y, Tang SCW, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Matching Grant for Joint Research
Start Date:03/2018


Project Title:The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):Zhang Y, Tang SCW, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:04/2018


Project Title:The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):Zhang Y, Tang SCW, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:06/2018


Project Title:The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):Zhang Y, Tang SCW, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2018


Project Title:The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):Zhang Y, Tang SCW, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Postdoctoral Hub Programme for ITF projects
Start Date:02/2019


Project Title:The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):Zhang Y, Tang SCW, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Postdoctoral Hub Programme for ITF projects
Start Date:03/2019


Project Title:The Pharmacological Effect and Mechanisms Study on Dendrobium Officinale - Yuye Decoction (DOY) to Improve Diabetic Nephropathy
Investigator(s):Zhang Y, Tang SCW, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:03/2019


List of Research Outputs

Au Y.N.E., Liang Y., Ip M.S.M., Zhang Y. and Mak J.C.W., Effects of Dendrobium officinale Polysaccharides in Cigarette Smoke-induced Inflammation in Human Airway Epithelial NCI-H292 Cells, 24th Medical Research Conference, Department of Medicine, HKU, Hong Kong Medical Journal. Hong Kong Medical Jouranal, 2019, 25: 9.
CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.
ZHANG L., NG T.B., Lam J.K.W., WANG S., Lao L., Zhang Y. and Sze C.W.S., Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers, Current Protein & Peptide Science. 2019, 20: 277-284.


Researcher : Zhang Z
Project Title:The Establishment of Neurobehavioral Experiments into the Acupuncture Course (BCHM3003, 針灸學) of Undergraduate Chinese Medicine Programs
Investigator(s):Zhang Z, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:07/2007


Project Title:The development of a clinical-case search system to introduce case-study learning mode into Chinese medical curricula
Investigator(s):Zhang Z, Wong HK
Department:School of Chinese Medicine
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:09/2008


Project Title:The herbal medicine Peony-Glycyrrhiza Decoction (PGD) as an adjunctive therapy to treat antipsychotic-induced hyperprolactinemia in female patients with schizophrenia: a double-blind, randomized, placebo-controlled study
Investigator(s):Zhang Z, Chen EYH
Department:School of Chinese Medicine
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:02/2012


Project Title:An assessor-blinded, randomised controlled trial of acupuncture to prevent chemobrain in breast cancer patients
Investigator(s):Zhang Z, Kwong A, Chan KW, Ho LM, Lee VHF, Lao L, Yeung WF, Sze CKH
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2015
Completion Date:08/2019


Project Title:Resveratrol and ginsenoside Rg1 combination protects against chemotherapy-induced cognitive impairment: synergistic mechanisms of cytokine-modulating and anti-neurotoxic actions
Investigator(s):Zhang Z, Lai SWC
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2017


Project Title:A double-blind, randomised,placebo-controlled trial of berberine as an adjuvant to treat antipsychotic-induced metabolic syndrome in patients with schizophrenia spectrum disorders
Investigator(s):Zhang Z, Chen EYH, Lee HME, Wong HK
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:10/2017


Project Title:A novel formula of natural compounds to protect against chemotherapy-induced cognitive impairment: a preclinical evaluation
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:03/2018


Project Title:Structural brain connectomic and blood and urine metabolomic differentiation of reactive and endogenous subtypes of major depressive disorder
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2018


Project Title:Behavioral, neuroimaging, biochemical, and molecular determination of Shexiang Baoxin Pill, a classic Chinese medicine formula, in ameliorating cognitive impairment in a rat model of vascular dementia
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2019


Project Title:The effect of acupuncture for insomnia in breast cancer patients undergoing chemotherapy: a randomized, sham-controlled trial
Investigator(s):Zhang Z, So TH, Chung KF, Jiang F, Chen H, Yang C, Lao L, Chang TYA
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2019


Project Title:Phytochemical and pharmacological characterization of novel and patentable agents from Lily bulb, a Chinese herbal medicine for menopause syndrome: involvement of distinct brain-uterus mechanisms from estrogen therapy
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Fund for Translational and Applied Research
Start Date:05/2019


List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019.
Chung K.F., Yeung W.F., Yu B.Y., Zhang S.P. and Zhang Z., Combined electroacupuncture and auricular acupuncture for primary insomnia: a randomised controlled trial of dose-response effect., Hong Kong Medical Journal . 2019, 25 Suppl 2: 28-33.
Jia M.F., Zhang Z., Li J.H., Ma X., Chen L.X. and Yang X.B., Molecular imprinting technology for microorganism analysis, TrAC Trends in Analytical Chemistry. 2018, 106: 190-201.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.
Liu C., Zhang Z., Kong Q.J., Zhang R.G. and Yang X.B., Enhancing the antitumor activity of tea polyphenols encapsulated in biodegradable nanogels by macromolecular self-assembly, RSC Advances. 2019, 9: 10004-10016.
SHI D. and Zhang Z., Chemotherapy-induced cognitive impairment is associated with cytokine dysregulation and disruptions in neuroplasticity, Molecular neurobiology . 2018.
Yeung W.F., Chung K.F., Zhang Z., Zhang S.P., Chan W.C., Ng R.M.K., Chan L.W.C., Ho L.M., Yu B.Y.M., Chan J.C.S., Lau N.C.L. and Lao L., Electroacupuncture for tapering off long-term benzodiazepine use: A randomized controlled trial, Journal of Psychiatric Research. 2018.
Zhang Z., Ma X., Jia M.F., Li B.W., Rong J. and Yang X.B., Deposition of CdTe quantum dots on microfluidic paper chips for rapid fluorescence detection of pesticide 2,4-D, The Analyst. 2018, 144: 1282-1291.


Researcher : Zhang Z
List of Research Outputs

CHEN X., LAM K.H., Feng Y., Xu K., Sze S.C.W., Tang S.C.W., Leung G.P.H., Lee C.K.F., Shi J., Yang Z., Li S., Zhang Z. and Zhang Y., Ellagitannins from Pomegranate Ameliorates 5-Fluorouracil-Induced Intestinal Mucositis in Rats while Enhancing Its Chemotoxicity against HT-29 Colorectal Cancer Cells through Intrinsic Apoptosis Induction, Journal of Agricultural and Food Chemistry. 2018, 66: 7054-7064.
Cheng I.S.C., LI R., Leung G.P.H., Li S.L., Kong M., Lao L., Zhang Z., Lin W.L., Ng E.H.Y., Rong J., Chen J., Su J., Zhang Y. and Meng W., Application of UPLC‐MS/MS to simultaneously detect four bioactive compounds in the tumour‐shrinking decoction (FM1523) for uterine fibroids treatment, Phytochemical Analysis. 2019.
Chung K.F., Yeung W.F., Yu B.Y., Zhang S.P. and Zhang Z., Combined electroacupuncture and auricular acupuncture for primary insomnia: a randomised controlled trial of dose-response effect., Hong Kong Medical Journal . 2019, 25 Suppl 2: 28-33.
Jia M.F., Zhang Z., Li J.H., Ma X., Chen L.X. and Yang X.B., Molecular imprinting technology for microorganism analysis, TrAC Trends in Analytical Chemistry. 2018, 106: 190-201.
LIU J., CHEN X., Chen H., Shi J., Leung G.P.H., Tang S.C.W., Lao L., Yip H.K.F., Lee C.K.F., Sze S.C.W., Zhang Z. and Zhang Y., Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitro and In vivo, Neuroscience. 2018, 394: 72-82.
Liu C., Zhang Z., Kong Q.J., Zhang R.G. and Yang X.B., Enhancing the antitumor activity of tea polyphenols encapsulated in biodegradable nanogels by macromolecular self-assembly, RSC Advances. 2019, 9: 10004-10016.
SHI D. and Zhang Z., Chemotherapy-induced cognitive impairment is associated with cytokine dysregulation and disruptions in neuroplasticity, Molecular neurobiology . 2018.
Yeung W.F., Chung K.F., Zhang Z., Zhang S.P., Chan W.C., Ng R.M.K., Chan L.W.C., Ho L.M., Yu B.Y.M., Chan J.C.S., Lau N.C.L. and Lao L., Electroacupuncture for tapering off long-term benzodiazepine use: A randomized controlled trial, Journal of Psychiatric Research. 2018.
Zhang Z., Ma X., Jia M.F., Li B.W., Rong J. and Yang X.B., Deposition of CdTe quantum dots on microfluidic paper chips for rapid fluorescence detection of pesticide 2,4-D, The Analyst. 2018, 144: 1282-1291.


Researcher : Zhao J
Project Title:Transcriptomic profiling of the gene networks reveals the roles of BDNF and RragA in the anti-depressive and analgesic activities of Chinese medicine Puerarin
Investigator(s):Zhao J, Rong J, Lao L, Meng W
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Mini Grant
Start Date:04/2018


List of Research Outputs

Zhao J., ZHU M., KUMAR M., NGO F.Y., Li Y., Lao L. and Rong J., A Pharmacological Appraisal of Neuroprotective and Neurorestorative Flavonoids Against Neurodegenerative Diseases, CNS & Neurological Disorders - Drug Targets. 2019, 18: 103-114.


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