Dept of Clinical Oncology

Research and Scholarship 2005

DEPARTMENT OF CLINICAL ONCOLOGY



Researcher : Au GKH
List of Research Outputs

Kwong D.L.W., Pow E.H.N., Sham J.S.T., McMillan A.S., Leung L...H...T..., Leung W.K., Chua D.T.T., Cheng C.K., Wu P.M. and Au G.K.H., Intensity modulated radiotherapy for early stage nasopharyngeal carcinoma:a prospective study on disease control and preservation of salivary function., Cancer. 2004, 101(7): 1584-93.
Law W.L., Ho J.W.C., Chan T.T., Au G.K.H. and Chu K.W., Outcome of anterior resection for stage II rectal cancer without radiation: the role of adjuvant chemotherapy, Diseases of the Colon & Rectum. 2005, 48(2): 218-226.
Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.


Researcher : Chan TT
List of Research Outputs

Law W.L., Ho J.W.C., Chan T.T., Au G.K.H. and Chu K.W., Outcome of anterior resection for stage II rectal cancer without radiation: the role of adjuvant chemotherapy, Diseases of the Colon & Rectum. 2005, 48(2): 218-226.


Researcher : Cheng CK
List of Research Outputs

Kwong D.L.W., Pow E.H.N., Sham J.S.T., McMillan A.S., Leung L...H...T..., Leung W.K., Chua D.T.T., Cheng C.K., Wu P.M. and Au G.K.H., Intensity modulated radiotherapy for early stage nasopharyngeal carcinoma:a prospective study on disease control and preservation of salivary function., Cancer. 2004, 101(7): 1584-93.
Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.


Researcher : Choy DTK
List of Research Outputs

Chua D.T.T., Ma J., Sham J.S.T., Mai H.Q., Choy D.T.K., Hong M.H., Lu T.X. and Min H.Q., Long-term Survival After Cisplatin-based Induction Chemotherapy And Radiotherapy For Nasopharyngeal Carcinoma: A Pooled Data Analysis Of Two Phase III Trials, Journal of Clinical Oncology. 2005, 23(6): 1118-1124.
Chua D.T.T., Sham J.S.T. and Choy D.T.K., Prognostic Impact Of Hemoglobin Levels On Treatment Outcome In Patients With Nasopharyngeal Carcinoma Treated With Sequential Chemoradiotherapy Or Radiotherapy Alone, Cancer. 2004, 101(2): 307-316.


Researcher : Chua DTT
Project Title:A randomized trial comparing external reirradiation followed by radiosurgery boost versus external reirradiation alone in locally recurrent nasopharyngeal carcinoma
Investigator(s):Chua DTT, Sham JST, Leung L.H.T.
Department:Clinical Oncology
Source(s) of Funding:Competitive Earmarked Research Grants (CERG)
Start Date:11/2001
Abstract:
To evaluate the impact of stereotactic radiosurgery (SRS) boost treatment on local control, survival and quality of life of patients with locally recurrent nasopharyngeal carcinoma (NPC) receiving external reirradiation.


Project Title:Immunohistochemical studies on expression of epidermal growth factor receptor in nasopharyngeal carcinoma and correlation with survival and failure patterns
Investigator(s):Chua DTT
Department:Clinical Oncology
Source(s) of Funding:Incentive Award for RGC CERG Fundable But Not Funded Projects
Start Date:07/2004
Abstract:
Refer to hard copy


List of Research Outputs

Cao K., Zheng Y., Ng S.P., Chua D.T.T., Sham J.S.T., Kwong D.L.W., Ng M.H. and Zheng B., Peripheral NK Cells Play a Complementary Role for Anti-tumor Immunity in Nasopharyngeal Carcinoma Patients., Keystone Symposia – Basic Aspects of Tumor Immunology II (C3). Keystone, Colorado, USA.. 2005.
Chua D.T.T., Induction chemotherapy with cisplatin and gemcitabine followed by reirradiation for locally recurrent nasopharyngeal carcinoma. , 41th Annual Meeting of the American Society of Clinical Oncology. 2005.
Chua D.T.T., Ma J., Sham J.S.T., Mai H.Q., Choy D.T.K., Hong M.H., Lu T.X. and Min H.Q., Long-term Survival After Cisplatin-based Induction Chemotherapy And Radiotherapy For Nasopharyngeal Carcinoma: A Pooled Data Analysis Of Two Phase III Trials, Journal of Clinical Oncology. 2005, 23(6): 1118-1124.
Chua D.T.T., Sham J.S.T. and Choy D.T.K., Prognostic Impact Of Hemoglobin Levels On Treatment Outcome In Patients With Nasopharyngeal Carcinoma Treated With Sequential Chemoradiotherapy Or Radiotherapy Alone, Cancer. 2004, 101(2): 307-316.
Chua D.T.T., Prognostic Impact of Hemoglobin Level in Patients with Nasopharyngeal Carcinoma Treated with Sequential Chemo-radiotherapy or Radiotherapy Alone, Forty-sixth Annual Meeting of the American Society for Therapeutic Radiology and Oncology. 2004.
Chua D.T.T., Reirradiation of nasopharyngeal carcinoma with intensity modulated radiation +/- radiosurgery boost, FourthTakahashi Memorial International Workshop on 3 Dimensional Conformal Radiotherapy.. 2004.
Fan H., Nicholls J.M., Chua D.T.T., Chan K.H., Sham J.S.T., Lee S. and Gulley M.L., Laboratory Markers Of Tumor Burden In Nasopharyngeal Carcinoma: A Comparison Of Viral Load And Serologic Tests For Epstein-barr Virus, International Journal of Cancer. 2004, 112(6): 1036-41.
Hui E.P., Leung S.F., Au J.S., Zee B., Tung S.Y., Chua D.T.T., Sze W.M., Law C.K., Leung T.W. and Chan A.T., Lung Metastasis Alone In Nasopharyngeal Carcinoma: A Relatively Favorable Prognostic Group. A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Cancer. 2004, 101(2): 300-306.
Kwong D.L.W., Pow E.H.N., Sham J.S.T., McMillan A.S., Leung L...H...T..., Leung W.K., Chua D.T.T., Cheng C.K., Wu P.M. and Au G.K.H., Intensity modulated radiotherapy for early stage nasopharyngeal carcinoma:a prospective study on disease control and preservation of salivary function., Cancer. 2004, 101(7): 1584-93.
Lee A.W.M., Au J.S., Teo P...M..., Leung T.W., Chua D.T.T., Sze W.M., Zee B...C..., Law S.C., Leung S.F., Tung S...Y..., Kwong D.L.W. and Lau W.H., Staging of nasopharyngeal carcinoma: suggestions for improving the current UICC/AJCC Staging System, Clin Oncol (R Coll Radiol). 2004, 16: 269-76.
Lee A.W.M., Sze W.M., Au J.S., Leung S.F., Leung T.W., Chua D.T.T., Zee B.C., Law S.C., Teo P.M., Tung S.Y., Kwong D.L.W. and Lau W.H., Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience, International Journal of Radiation Oncology Biology Physcis. 2005, 61: 1107-16.
Li G., Sham J.S.T., Yang J., Su C., Xue H., Chua D.T.T., Sun L., Zhang Q., Cui Z., Wu M. and Qian Q., Potent Antitumor Efficacy Of An E1b 55kda-deficient Adenovirus Carrying Murine Endostatin In Hepatocellular Carcinoma, International Journal of Cancer. 2005, 113(4): 640-648.
Lin S.S., Chua D.T.T., Ko C.F., Chik S.C.C., Law H.Y., Lee D.C.W., Sham J.S.T. and Lau A.S.Y., Cytokine and matrix metalloproteinase regulation by latent membrane protein 1., In: BSS Lin, D Chua, FCF Ko, SC Chik, AHY Law, DCW Lee, JST Sham and AS Lau., Ruby Jubilee Scientific Meeting. 24-26 September 2004.. 2004.
Lin S.S., Chua D.T.T., Ko C.F., Chik S.C.C., Law H.Y., Lee D.C.W., Sham J.S.T. and Lau A.S.Y., Regulation of Cytokine and Martrix Metalloproteinases by Epstein-Barr Virus Latent Membrane Protein 1, Ruby Jubilee Scientific Meeting, HK, 24-26 Sepember 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 51.
Lin S.S., Chua D.T.T., Law H.Y., Lee D.C.W., Sham J.S.T. and Lau A.S.Y., Regulation of cytokine and matrix metalloproteinases by Epstein-Barr virus latent membrane protein 1., In: Belinda SS Lin, Daniel Chua, Frankie CF Ko, Anna HY Law, Davy CW Lee, Jonathan ST Sham and Allan S Lau., 11th Hong Kong International Cancer Congress. 10 November 2004, Hong Kong.. 2004.
Liu W., Chan Y.K., Chan S.Y., Yip S.P., Cheung A.N.Y., Chua D.T.T., Ngan H.Y.S. and Khoo U.S., BRCA1 gene promoter polymorphisms associated with breast cancer risk, 96th Annual Meeting 2005, American Association for Cancer Research, Anaheim, Orange Country, California, USA, April 16-20, 2005.
Su C.Q., Sham J.S.T., Xue H.B., Wang X.H., Chua D.T.T., Cui Z.F., Peng L.H., Lie L.F., Jiang L.H., Wu M.C. and Qian Q., Potent Antitumoral Efficacy Of A Novel Replicative Adenovirus Cnhk300 Targeting Telomerase-positive Cancer Cells, Journal of Cancer Research and Clinical Oncology. 2004, 130(10): 591-603.
Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.
Zhang Q., Nie M., Sham J.S.T., Su C., Xue H., Chua D.T.T., Wang W., Cui Z., Liu Y., Liu C., Jiang M., Fang G., Liu X., Wu M. and Qian Q., Effective Gene-viral Therapy For Telomerase-positive Cancers By Selective Replicative-competent Adenovirus Combining With Endostatin Gene, Cancer Research. 2004, 64(15): 5390-5397.


Researcher : Fan Z
List of Research Outputs

Wang L.D., Qin Y., Fan Z., Kwong D.L.W., He X., Chang Z.W., Li J.L., Guan X.Y., Tsao G.S.W., Sham J.S.T., Zheng S., Yang C.S. and Li J., Gain of 6p, 20p and loss of 10p, 10q in esophageal squamoud cell carcinoma are associated with lymph node metastasis, Proceedings of the American Association for Cancer Research. 2004, 45: 744 No. 3214.


Researcher : Guan XY
Project Title:Isolation of genes related to the pathogenesis of hepatocellular carcinoma and nasopharyngeal carcinoma: identification of the association between amplication of oncogenes and cancer prognosis
Investigator(s):Guan XY
Department:Clinical Oncology
Source(s) of Funding:Matching Fund for NSFC Young Researcher Award
Start Date:05/2001
Abstract:
To study isolation of genes related to the pathogenesis of hepatocellular carcinoma and nasopharyngeal carcinoma: identification of the association between amplication of oncogenes and cancer prognosis.


Project Title:Development of novel tools in the diagnosis and treatment of leukemia
Investigator(s):Guan XY, Sham JST, Tong C.R., Lu D.P.
Department:Clinical Oncology
Source(s) of Funding:NSFC/RGC Joint Research Scheme
Start Date:12/2001
Abstract:
To generate chromosome band-specific painting probes for all common breakpoints in ALL and acute myeloid leukemia (AML) by chromosome microdissection; to isolate at least one novel fusion gene from patients with acute leukemia; to use the fusion gene as DNA vaccine and its effect of activating anti-leukemia immune response in leukemia SCID-hu mice model will be detected.


Project Title:Basic research for the mechanisms of development and progression of malignant tumors
Investigator(s):Guan XY
Department:Clinical Oncology
Source(s) of Funding:Matching Fund for National Key Basic Research Development Scheme (973 Projects)
Start Date:03/2002
Abstract:
To identify recurrent genomic alterations in 30 primary adenocarcinomas of lung and carcinomas using CGH technology; to establish gene expression profiles for lung cancer using cDNA microarray technique; to establish 10 pairs of xenografts of primary and their matched metastatic lung cancer by transplanting tumor cells into nude mice; to study the differences between primary and metastasis lung cancer with mentioned xenografts.


Project Title:Characterization of roles of a new candidate oncogene eIF-5A2 in cancer development
Investigator(s):Guan XY
Department:Clinical Oncology
Source(s) of Funding:Competitive Earmarked Research Grants (CERG)
Start Date:10/2002
Abstract:
The project is proposed to understand the tumorigenicity of the eIF-5A2 gene by in vitro assays (soft-agar assay and focus-formation assay) and in vivo approach (tumour formation in nude mouse). A broad survey using high-throughput tissue microarray will be employed to investigate the association of eIF-5A2 amplification and clinical features of various cancers by fluorescence in situ hybridization (FISH).


Project Title:Identification of the mechanism of hepatitis B virus (HBV) integration in the development of hepatocellular carcinoma (HCC)
Investigator(s):Guan XY
Department:Clinical Oncology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2003
Abstract:
Although the integration of HBV has been associated with the development of HCC, the molecular mehanism remains unclear. It is believed that HBV and host factors (e.g. inflammatory/genetic factors) may contribute together to the process of HCC development. Although the association of HBV and HCC development has been widely studied, only a limited number of integrated HBV have been completely analyzed. Therefore, additional studies with more cases are needed to understand roles of HBV integrants involved in the HCC development. In order to obtain additional insight into the correlation of HBV integration and HCC development, integrated HBV in 10-20 HCC cases will be isolated and characterized by sequencing analysis. findings in this project may greatly facilitate the early diagnosis and prevention of HCC.


Project Title:Isolation and characterization of oncogenes within a frequently amplified region at 19q13.1 in ovarian cancer
Investigator(s):Guan XY
Department:Clinical Oncology
Source(s) of Funding:Incentive Award for RGC CERG Fundable But Not Funded Projects
Start Date:07/2003
Abstract:
To characterize the amplification of 19q13.1 in four ovarian cancer cell lines and to determine the overlapping MAR; to identify candidate oncogenes within the overlapping MAR; to investigate the association between the amplification of 19q13.1 and clinical features of ovarian cancer by tissue microarray; to study the tumorigenesity of SEI-1 gene; to characterize other candidate oncogenes within the overlapping MAR.


Project Title:Characterization of oncogenic role of SEI-1 in the development of ovarian cancer
Investigator(s):Guan XY
Department:Clinical Oncology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2004
Abstract:
To study the tumorigenisity of SEI-1 using both in vitro and in vivo approaches; to define the clinical and pathological significance of the amplification of SEI-1 in ovarian cancer.


Project Title:Characterization of roles of a novel oncogene ALC-1 in the development of hepatocellular carcinoma
Investigator(s):Guan XY, Huang J
Department:Clinical Oncology
Source(s) of Funding:Competitive Earmarked Research Grants (CERG)
Start Date:10/2004
Abstract:
To confirm the tumorigenic role of ALC-1; to investigate the biochemical properties of ALC-1; to study the functions of ALC-1 in vivo by the generation and characterization of transgenic mice overexpressing the ALC-1 gene; to define the clinical and pathological significance of the amplification of ALC-1 in HCC using high-throughput tissue microarray.


Project Title:Characterization of roles of a novel oncogene ALC-1 in the development of hepatocellular carcinoma
Investigator(s):Guan XY
Department:Clinical Oncology
Source(s) of Funding:Merit Award for RGC CERG Funded Projects
Start Date:01/2005
Abstract:
Refer to hard copy


List of Research Outputs

Chan K.L., Guan X.Y. and Ng I.O.L., High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma, Human Pathology. 2004, 35(11): 1324-1331.
Chung C.M., Man W.Y.C., Jin Y., Jin C., Guan X.Y., Wang Q., Wan T.S.K., Cheung A. and Tsao G.S.W., Amplification and overexpression of Aurora kinase A (AURKA) in immortalized human ovarian epithelial (HOSE) cells, Molecular Carcinogenesis. 2005, 43(3): 165-174.
Deng W., Tsao G.S.W., Guan X.Y., Lucas J.N., Si H., Leung C.S., Mak P., Wang L.D. and Cheung A., Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines, Oncogene. 2004, 23: 9090-9101.
Hung H.L., Bangarusamy D.K., Xie D., Cheung A.K.L., Cheng Y., Kumaran M.K., Millar L., Liu E.T.B., Guan X.Y., Sham J.S.T., Fang Y., Li L., Wang N., Protopopov A.I., Zabarovsky E.R., Tsao G.S.W., Stanbridge E.J. and Lung M.L., THY1 is a candidate tumour suppressor gene with decreased expression in metastatic nasopharyngeal carcinoma, Oncogene. 2005, 24: 6525-6532.
Lau B.S.H. and Guan X.Y., Cytogenetic and molecular genetic alterations in hepatocellular carcinoma, Acta. Pharmacol. Sin.. 2005, 26(6): 659-665.
Qin Y., Wang L., Kwong D.L.W., Guan X.Y., Zhuang Z., Fan Z., An J. and Tsao G.S.W., Comparative genomic hybridization of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma in high-incidence region of esophageal carcinoma, Zhonghua Yi Xue Yi Chuan Xue Za Zhi. Linzhou Henan, 2004, 21(6): 625-8.
Qin Y.R., Wang L.D., Kwong D.L.W., Gao S.S., Guan X.Y., Zhuang Z.H., Fan Z.M., Deng W. and Hu L., Comparative genomic hybridization: the profile of chromosomal imbalances in esophageal squamous cell carcinoma, Zhanghua Bing Li Xue Za Zhi. 2005, 34(2): 80-83.
Tai L.S., Fang Y., Sham J.S.T., Deng W., Hu L., Xie D., Tsao G.S.W., Cheung A. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Oncology Report. 2005, 13(6): 1029-1032.
Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., Celecoxib suppresses HCC development via the cell cycle arrest pathway (Poster Presentation), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005.
Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., The significance of cyclooxygenase-2 in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005.
Tjia W.M., Sham J.S.T., Hu L., Tai L.S. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Cancer Genetics Cytogenetics. 2005, 158(1): 61-66.
Wang L.D., Qin Y., Fan Z., Kwong D.L.W., He X., Chang Z.W., Li J.L., Guan X.Y., Tsao G.S.W., Sham J.S.T., Zheng S., Yang C.S. and Li J., Gain of 6p, 20p and loss of 10p, 10q in esophageal squamoud cell carcinoma are associated with lymph node metastasis, Proceedings of the American Association for Cancer Research. 2004, 45: 744 No. 3214.
Xie D., Sham J.S.T., Zeng W.F., Che L.H., Zhang M., Wu H.X., Lin H.L., Wen J.M., Lau B.S.H. and Guan X.Y., Oncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progression, World Journal of Gastroenterology. 2005, 11(21): 3285-3289.
Xie D., Lau B.S.H., Sham J.S.T., Wu Q.L., Fang Y., Liang Z.H., Che L.H., Zeng Y.X. and Guan X.Y., Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma, Cancer. 2005, 103(2): 277-283.
Zhu L., Chow L.W.C., Loo T.Y., Guan X.Y. and Toi M., Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial, Clinic Cancer Research. 2004, 10(14): 4639-4644.


Researcher : Hu L
List of Research Outputs

Tai L.S., Fang Y., Sham J.S.T., Deng W., Hu L., Xie D., Tsao G.S.W., Cheung A. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Oncology Report. 2005, 13(6): 1029-1032.
Tjia W.M., Sham J.S.T., Hu L., Tai L.S. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Cancer Genetics Cytogenetics. 2005, 158(1): 61-66.


Researcher : Kwong DLW
Project Title:A randomised controlled trial comparing intensity modulated radiotherapy with conventional radiotherapy in treatment of nasopharyngeal carcinoma
Investigator(s):Kwong DLW, McMillan AS, Lee PWH
Department:Clinical Oncology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2002
Completion Date:09/2004
Abstract:
To compare the efficacy of IMRT versus conventional radiotherapy in achieving loco-regional disease control and survival among patients with T2N0/N1 nasopharyngeal carcinoma; to study radiation complications for comparing the incidence and nature of complications for patients treated with IMRT versus conventional radiotherapy.


Project Title:The use of intensity modulated radiotherapy in reduction of long term complications of radiotherapy among patients treated for early stage nasopharyngeal carcinoma
Investigator(s):Kwong DLW, McMillan AS, Sham JST, Lee PWH
Department:Clinical Oncology
Source(s) of Funding:Incentive Award for RGC CERG Fundable But Not Funded Projects
Start Date:07/2003
Abstract:
To compare the efficacy of IMRT versus conventional radiotherapy in achieving loco-regional disease control and survival among patients with early, T1-2, No/N1 nasopharyngeal carcinoma; to carry out a prospective study on radiation complications to compare the incidence and nature of complications for patients treated with IMRT versus conventional radiotherapy.


List of Research Outputs

Cao K., Zheng Y., Ng S.P., Chua D.T.T., Sham J.S.T., Kwong D.L.W., Ng M.H. and Zheng B., Peripheral NK Cells Play a Complementary Role for Anti-tumor Immunity in Nasopharyngeal Carcinoma Patients., Keystone Symposia – Basic Aspects of Tumor Immunology II (C3). Keystone, Colorado, USA.. 2005.
Khong P.L., Ng K.C., Kwong D.L.W., Ooi C.G.C. and Chan G.C.F., Cortical laminar necrosis in childhood intracranial germ cell tumor survivors, Pediatrics Blood Cancer. Wiley InterScience, 2005, 44: 412-415.
Khong P.L., Leung L.H.T., Chan G.C.F., Kwong D.L.W., Wong W.H.S., Cao G. and Ooi C.G.C., White matter anisotropy in childhood medulloblastoma survivors: association with neurotoxicity risk factors, Radiology. 2005, 236: 647-652.
Khong P.L., Leung L.H.T., Fung A.S.M., Kwong D.L.W., Qiu D., McAlonan G.M., Fong D.Y.T., Cao G., Yip L.C.K., Ooi C.G.C. and Chan G.C.F., White matter fractional anisotropy (FA) in the assessment of treatment-induced neurotoxicity in childhood cancer survivors: association with neurocognitive function, ISMRM 13th Scientific Meeting and Exhibition, Florida, U.S.A., 7-13 May 2005.
Kwong D.L.W., Pow E.H.N., Sham J.S.T., McMillan A.S., Leung L...H...T..., Leung W.K., Chua D.T.T., Cheng C.K., Wu P.M. and Au G.K.H., Intensity modulated radiotherapy for early stage nasopharyngeal carcinoma:a prospective study on disease control and preservation of salivary function., Cancer. 2004, 101(7): 1584-93.
Kwong D.L.W., Radiation Dose Escalation for Locally Advanced Nasopharyngeal Carcinoma, East-West Symposium on Nasopharyngeal Carcinoma including Wharton Research Day, June 16-18, 2005, Toronto, Canada. 2005.
Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Oesophageal cancer located above the tracheal bifurcation is an independent poor prognostic factor. Neoadjuvant chemoradiation improves survival (Abstract), Gut. 2004, 53 (Supplement VI): A279-A280.
Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Oesophageal cancer located above the tracheal bifurcation is an independent poor prognostic factor. Neoadjuvant chemoradiation improves survival (Abstract), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September. 2004.
Lee A.W.M., Au J.S., Teo P...M..., Leung T.W., Chua D.T.T., Sze W.M., Zee B...C..., Law S.C., Leung S.F., Tung S...Y..., Kwong D.L.W. and Lau W.H., Staging of nasopharyngeal carcinoma: suggestions for improving the current UICC/AJCC Staging System, Clin Oncol (R Coll Radiol). 2004, 16: 269-76.
Lee A.W.M., Sze W.M., Au J.S., Leung S.F., Leung T.W., Chua D.T.T., Zee B.C., Law S.C., Teo P.M., Tung S.Y., Kwong D.L.W. and Lau W.H., Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience, International Journal of Radiation Oncology Biology Physcis. 2005, 61: 1107-16.
Qi Y., Chiu J., Wang L., Kwong D.L.W. and He Q., Comparative proteomic analysis of esophageal squamous cell carcinoma, Proteomics. 2005, 5(11): 2960-71.
Qin Y., Wang L., Kwong D.L.W., Guan X.Y., Zhuang Z., Fan Z., An J. and Tsao G.S.W., Comparative genomic hybridization of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma in high-incidence region of esophageal carcinoma, Zhonghua Yi Xue Yi Chuan Xue Za Zhi. Linzhou Henan, 2004, 21(6): 625-8.
Qin Y.R., Wang L.D., Kwong D.L.W., Gao S.S., Guan X.Y., Zhuang Z.H., Fan Z.M., Deng W. and Hu L., Comparative genomic hybridization: the profile of chromosomal imbalances in esophageal squamous cell carcinoma, Zhanghua Bing Li Xue Za Zhi. 2005, 34(2): 80-83.
Wang L.D., Qin Y., Fan Z., Kwong D.L.W., He X., Chang Z.W., Li J.L., Guan X.Y., Tsao G.S.W., Sham J.S.T., Zheng S., Yang C.S. and Li J., Gain of 6p, 20p and loss of 10p, 10q in esophageal squamoud cell carcinoma are associated with lymph node metastasis, Proceedings of the American Association for Cancer Research. 2004, 45: 744 No. 3214.
Wei W.I., Yuen P.W., Ng W.M., Ho W.K., Kwong D.L.W. and Sham J.S.T., Quantitative analysis of plasma cell-free epstein-barr virus DNA in nasopharyngeal carcinoma after salvage nasopharyngectomy: a prospective study, Head & Neck. 2004, 26: 878-883.
Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Elevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinoma, European Journal of surgical Oncology. 2005, 31: 555-558.
Wu W.C.V., Sham J.S.T. and Kwong D.L.W., Inverse planning in three-dimensional conformal and intensity-modulated radiotherapy of midthoracic oesophageal cancer, Br. J. Radiol. 2004, 77: 568-72.


Researcher : Lau BSH
List of Research Outputs

Lau B.S.H. and Guan X.Y., Cytogenetic and molecular genetic alterations in hepatocellular carcinoma, Acta. Pharmacol. Sin.. 2005, 26(6): 659-665.
Xie D., Sham J.S.T., Zeng W.F., Che L.H., Zhang M., Wu H.X., Lin H.L., Wen J.M., Lau B.S.H. and Guan X.Y., Oncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progression, World Journal of Gastroenterology. 2005, 11(21): 3285-3289.
Xie D., Lau B.S.H., Sham J.S.T., Wu Q.L., Fang Y., Liang Z.H., Che L.H., Zeng Y.X. and Guan X.Y., Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma, Cancer. 2005, 103(2): 277-283.


Researcher : Lau WH
List of Research Outputs

Lee A.W.M., Au J.S., Teo P...M..., Leung T.W., Chua D.T.T., Sze W.M., Zee B...C..., Law S.C., Leung S.F., Tung S...Y..., Kwong D.L.W. and Lau W.H., Staging of nasopharyngeal carcinoma: suggestions for improving the current UICC/AJCC Staging System, Clin Oncol (R Coll Radiol). 2004, 16: 269-76.
Lee A.W.M., Sze W.M., Au J.S., Leung S.F., Leung T.W., Chua D.T.T., Zee B.C., Law S.C., Teo P.M., Tung S.Y., Kwong D.L.W. and Lau W.H., Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience, International Journal of Radiation Oncology Biology Physcis. 2005, 61: 1107-16.


Researcher : Law CK
List of Research Outputs

Hui E.P., Leung S.F., Au J.S., Zee B., Tung S.Y., Chua D.T.T., Sze W.M., Law C.K., Leung T.W. and Chan A.T., Lung Metastasis Alone In Nasopharyngeal Carcinoma: A Relatively Favorable Prognostic Group. A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Cancer. 2004, 101(2): 300-306.
Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.


Researcher : Lee AWM
List of Research Outputs

Lee A.W.M., Au J.S., Teo P...M..., Leung T.W., Chua D.T.T., Sze W.M., Zee B...C..., Law S.C., Leung S.F., Tung S...Y..., Kwong D.L.W. and Lau W.H., Staging of nasopharyngeal carcinoma: suggestions for improving the current UICC/AJCC Staging System, Clin Oncol (R Coll Radiol). 2004, 16: 269-76.
Lee A.W.M., Sze W.M., Au J.S., Leung S.F., Leung T.W., Chua D.T.T., Zee B.C., Law S.C., Teo P.M., Tung S.Y., Kwong D.L.W. and Lau W.H., Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience, International Journal of Radiation Oncology Biology Physcis. 2005, 61: 1107-16.
Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.


Researcher : Ngan KC
List of Research Outputs

Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.


Researcher : Qian Q
List of Research Outputs

Li G., Sham J.S.T., Yang J., Su C., Xue H., Chua D.T.T., Sun L., Zhang Q., Cui Z., Wu M. and Qian Q., Potent Antitumor Efficacy Of An E1b 55kda-deficient Adenovirus Carrying Murine Endostatin In Hepatocellular Carcinoma, International Journal of Cancer. 2005, 113(4): 640-648.
Li G.C., Yang J.M., Nie M.M., Su C.G., Sun L.C., Qian Y.Z., Fang G.E., Sham J.S.T., Wu M.C. and Qian Q., Potent antitumoral effects of a novel gene-viral therapeutic system CNHK300-mEndostatin in hepatocellular carcinoma, Chinese Medicine Journal. 2005, 118(3): 179-85.
Su C.Q., Sham J.S.T., Xue H.B., Wang X.H., Chua D.T.T., Cui Z.F., Peng L.H., Lie L.F., Jiang L.H., Wu M.C. and Qian Q., Potent Antitumoral Efficacy Of A Novel Replicative Adenovirus Cnhk300 Targeting Telomerase-positive Cancer Cells, Journal of Cancer Research and Clinical Oncology. 2004, 130(10): 591-603.
Zhang Q., Nie M., Sham J.S.T., Su C., Xue H., Chua D.T.T., Wang W., Cui Z., Liu Y., Liu C., Jiang M., Fang G., Liu X., Wu M. and Qian Q., Effective Gene-viral Therapy For Telomerase-positive Cancers By Selective Replicative-competent Adenovirus Combining With Endostatin Gene, Cancer Research. 2004, 64(15): 5390-5397.


Researcher : Qin Y
List of Research Outputs

Wang L.D., Qin Y., Fan Z., Kwong D.L.W., He X., Chang Z.W., Li J.L., Guan X.Y., Tsao G.S.W., Sham J.S.T., Zheng S., Yang C.S. and Li J., Gain of 6p, 20p and loss of 10p, 10q in esophageal squamoud cell carcinoma are associated with lymph node metastasis, Proceedings of the American Association for Cancer Research. 2004, 45: 744 No. 3214.


Researcher : Sham JST
List of Research Outputs

Cao K., Zheng Y., Ng S.P., Chua D.T.T., Sham J.S.T., Kwong D.L.W., Ng M.H. and Zheng B., Peripheral NK Cells Play a Complementary Role for Anti-tumor Immunity in Nasopharyngeal Carcinoma Patients., Keystone Symposia – Basic Aspects of Tumor Immunology II (C3). Keystone, Colorado, USA.. 2005.
Chua D.T.T., Ma J., Sham J.S.T., Mai H.Q., Choy D.T.K., Hong M.H., Lu T.X. and Min H.Q., Long-term Survival After Cisplatin-based Induction Chemotherapy And Radiotherapy For Nasopharyngeal Carcinoma: A Pooled Data Analysis Of Two Phase III Trials, Journal of Clinical Oncology. 2005, 23(6): 1118-1124.
Chua D.T.T., Sham J.S.T. and Choy D.T.K., Prognostic Impact Of Hemoglobin Levels On Treatment Outcome In Patients With Nasopharyngeal Carcinoma Treated With Sequential Chemoradiotherapy Or Radiotherapy Alone, Cancer. 2004, 101(2): 307-316.
Fan H., Nicholls J.M., Chua D.T.T., Chan K.H., Sham J.S.T., Lee S. and Gulley M.L., Laboratory Markers Of Tumor Burden In Nasopharyngeal Carcinoma: A Comparison Of Viral Load And Serologic Tests For Epstein-barr Virus, International Journal of Cancer. 2004, 112(6): 1036-41.
Hung H.L., Bangarusamy D.K., Xie D., Cheung A.K.L., Cheng Y., Kumaran M.K., Millar L., Liu E.T.B., Guan X.Y., Sham J.S.T., Fang Y., Li L., Wang N., Protopopov A.I., Zabarovsky E.R., Tsao G.S.W., Stanbridge E.J. and Lung M.L., THY1 is a candidate tumour suppressor gene with decreased expression in metastatic nasopharyngeal carcinoma, Oncogene. 2005, 24: 6525-6532.
Kwong D.L.W., Pow E.H.N., Sham J.S.T., McMillan A.S., Leung L...H...T..., Leung W.K., Chua D.T.T., Cheng C.K., Wu P.M. and Au G.K.H., Intensity modulated radiotherapy for early stage nasopharyngeal carcinoma:a prospective study on disease control and preservation of salivary function., Cancer. 2004, 101(7): 1584-93.
Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Oesophageal cancer located above the tracheal bifurcation is an independent poor prognostic factor. Neoadjuvant chemoradiation improves survival (Abstract), Gut. 2004, 53 (Supplement VI): A279-A280.
Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Oesophageal cancer located above the tracheal bifurcation is an independent poor prognostic factor. Neoadjuvant chemoradiation improves survival (Abstract), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September. 2004.
Li G., Sham J.S.T., Yang J., Su C., Xue H., Chua D.T.T., Sun L., Zhang Q., Cui Z., Wu M. and Qian Q., Potent Antitumor Efficacy Of An E1b 55kda-deficient Adenovirus Carrying Murine Endostatin In Hepatocellular Carcinoma, International Journal of Cancer. 2005, 113(4): 640-648.
Li G.C., Yang J.M., Nie M.M., Su C.G., Sun L.C., Qian Y.Z., Fang G.E., Sham J.S.T., Wu M.C. and Qian Q., Potent antitumoral effects of a novel gene-viral therapeutic system CNHK300-mEndostatin in hepatocellular carcinoma, Chinese Medicine Journal. 2005, 118(3): 179-85.
Lin S.S., Chua D.T.T., Ko C.F., Chik S.C.C., Law H.Y., Lee D.C.W., Sham J.S.T. and Lau A.S.Y., Cytokine and matrix metalloproteinase regulation by latent membrane protein 1., In: BSS Lin, D Chua, FCF Ko, SC Chik, AHY Law, DCW Lee, JST Sham and AS Lau., Ruby Jubilee Scientific Meeting. 24-26 September 2004.. 2004.
Lin S.S., Chua D.T.T., Ko C.F., Chik S.C.C., Law H.Y., Lee D.C.W., Sham J.S.T. and Lau A.S.Y., Regulation of Cytokine and Martrix Metalloproteinases by Epstein-Barr Virus Latent Membrane Protein 1, Ruby Jubilee Scientific Meeting, HK, 24-26 Sepember 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 51.
Lin S.S., Chua D.T.T., Law H.Y., Lee D.C.W., Sham J.S.T. and Lau A.S.Y., Regulation of cytokine and matrix metalloproteinases by Epstein-Barr virus latent membrane protein 1., In: Belinda SS Lin, Daniel Chua, Frankie CF Ko, Anna HY Law, Davy CW Lee, Jonathan ST Sham and Allan S Lau., 11th Hong Kong International Cancer Congress. 10 November 2004, Hong Kong.. 2004.
Su C.Q., Sham J.S.T., Xue H.B., Wang X.H., Chua D.T.T., Cui Z.F., Peng L.H., Lie L.F., Jiang L.H., Wu M.C. and Qian Q., Potent Antitumoral Efficacy Of A Novel Replicative Adenovirus Cnhk300 Targeting Telomerase-positive Cancer Cells, Journal of Cancer Research and Clinical Oncology. 2004, 130(10): 591-603.
Tai L.S., Fang Y., Sham J.S.T., Deng W., Hu L., Xie D., Tsao G.S.W., Cheung A. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Oncology Report. 2005, 13(6): 1029-1032.
Tjia W.M., Sham J.S.T., Hu L., Tai L.S. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Cancer Genetics Cytogenetics. 2005, 158(1): 61-66.
Wang L.D., Qin Y., Fan Z., Kwong D.L.W., He X., Chang Z.W., Li J.L., Guan X.Y., Tsao G.S.W., Sham J.S.T., Zheng S., Yang C.S. and Li J., Gain of 6p, 20p and loss of 10p, 10q in esophageal squamoud cell carcinoma are associated with lymph node metastasis, Proceedings of the American Association for Cancer Research. 2004, 45: 744 No. 3214.
Wei W.I. and Sham J.S.T., Nasopharyngeal carcinoma, Lancet. 2005, 365: 2041-2054.
Wei W.I., Yuen P.W., Ng W.M., Ho W.K., Kwong D.L.W. and Sham J.S.T., Quantitative analysis of plasma cell-free epstein-barr virus DNA in nasopharyngeal carcinoma after salvage nasopharyngectomy: a prospective study, Head & Neck. 2004, 26: 878-883.
Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Elevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinoma, European Journal of surgical Oncology. 2005, 31: 555-558.
Wu W.C.V., Sham J.S.T. and Kwong D.L.W., Inverse planning in three-dimensional conformal and intensity-modulated radiotherapy of midthoracic oesophageal cancer, Br. J. Radiol. 2004, 77: 568-72.
Xie D., Sham J.S.T., Zeng W.F., Che L.H., Zhang M., Wu H.X., Lin H.L., Wen J.M., Lau B.S.H. and Guan X.Y., Oncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progression, World Journal of Gastroenterology. 2005, 11(21): 3285-3289.
Xie D., Lau B.S.H., Sham J.S.T., Wu Q.L., Fang Y., Liang Z.H., Che L.H., Zeng Y.X. and Guan X.Y., Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma, Cancer. 2005, 103(2): 277-283.
Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.
Zhang Q., Nie M., Sham J.S.T., Su C., Xue H., Chua D.T.T., Wang W., Cui Z., Liu Y., Liu C., Jiang M., Fang G., Liu X., Wu M. and Qian Q., Effective Gene-viral Therapy For Telomerase-positive Cancers By Selective Replicative-competent Adenovirus Combining With Endostatin Gene, Cancer Research. 2004, 64(15): 5390-5397.


Researcher : Sze WM
List of Research Outputs

Hui E.P., Leung S.F., Au J.S., Zee B., Tung S.Y., Chua D.T.T., Sze W.M., Law C.K., Leung T.W. and Chan A.T., Lung Metastasis Alone In Nasopharyngeal Carcinoma: A Relatively Favorable Prognostic Group. A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Cancer. 2004, 101(2): 300-306.
Lee A.W.M., Au J.S., Teo P...M..., Leung T.W., Chua D.T.T., Sze W.M., Zee B...C..., Law S.C., Leung S.F., Tung S...Y..., Kwong D.L.W. and Lau W.H., Staging of nasopharyngeal carcinoma: suggestions for improving the current UICC/AJCC Staging System, Clin Oncol (R Coll Radiol). 2004, 16: 269-76.
Lee A.W.M., Sze W.M., Au J.S., Leung S.F., Leung T.W., Chua D.T.T., Zee B.C., Law S.C., Teo P.M., Tung S.Y., Kwong D.L.W. and Lau W.H., Treatment results for nasopharyngeal carcinoma in the modern era: the Hong Kong experience, International Journal of Radiation Oncology Biology Physcis. 2005, 61: 1107-16.
Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.


Researcher : Tai LS
List of Research Outputs

Tai L.S., Fang Y., Sham J.S.T., Deng W., Hu L., Xie D., Tsao G.S.W., Cheung A. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Oncology Report. 2005, 13(6): 1029-1032.
Tjia W.M., Sham J.S.T., Hu L., Tai L.S. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Cancer Genetics Cytogenetics. 2005, 158(1): 61-66.


Researcher : Tjia WM
List of Research Outputs

Tjia W.M., Sham J.S.T., Hu L., Tai L.S. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Cancer Genetics Cytogenetics. 2005, 158(1): 61-66.


Researcher : Wu PM
List of Research Outputs

Kwong D.L.W., Pow E.H.N., Sham J.S.T., McMillan A.S., Leung L...H...T..., Leung W.K., Chua D.T.T., Cheng C.K., Wu P.M. and Au G.K.H., Intensity modulated radiotherapy for early stage nasopharyngeal carcinoma:a prospective study on disease control and preservation of salivary function., Cancer. 2004, 101(7): 1584-93.


Researcher : Wu WCV
List of Research Outputs

Wu W.C.V., Sham J.S.T. and Kwong D.L.W., Inverse planning in three-dimensional conformal and intensity-modulated radiotherapy of midthoracic oesophageal cancer, Br. J. Radiol. 2004, 77: 568-72.


Researcher : Xie D
List of Research Outputs

Hung H.L., Bangarusamy D.K., Xie D., Cheung A.K.L., Cheng Y., Kumaran M.K., Millar L., Liu E.T.B., Guan X.Y., Sham J.S.T., Fang Y., Li L., Wang N., Protopopov A.I., Zabarovsky E.R., Tsao G.S.W., Stanbridge E.J. and Lung M.L., THY1 is a candidate tumour suppressor gene with decreased expression in metastatic nasopharyngeal carcinoma, Oncogene. 2005, 24: 6525-6532.
Tai L.S., Fang Y., Sham J.S.T., Deng W., Hu L., Xie D., Tsao G.S.W., Cheung A. and Guan X.Y., Establishment and characterization of a human non-small cell lung cancer cell line, Oncology Report. 2005, 13(6): 1029-1032.
Xie D., Sham J.S.T., Zeng W.F., Che L.H., Zhang M., Wu H.X., Lin H.L., Wen J.M., Lau B.S.H. and Guan X.Y., Oncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progression, World Journal of Gastroenterology. 2005, 11(21): 3285-3289.
Xie D., Lau B.S.H., Sham J.S.T., Wu Q.L., Fang Y., Liang Z.H., Che L.H., Zeng Y.X. and Guan X.Y., Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma, Cancer. 2005, 103(2): 277-283.


Researcher : Yau TK
List of Research Outputs

Yu K.H., Leung S.F., Tung S.Y., Zee B., Chua D.T.T., Sze W.M., Law C.K., Kam M.K., Leung T.W., Sham J.S.T., Lee A.W.M., Au J.S., Hui E.P., Sze W.K., Cheng C.K., Yau T.K., Ngan K.C., Wong F.C., Au G.K.H. and Chan A.T., Survival Outcome Of Patients With Nasopharyngeal Carcinoma With First Local Failure: A Study By The Hong Kong Nasopharyngeal Carcinoma Study Group, Head and Neck. 2005, 27(5): 397-405.


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