School of Chinese Medicine

SCHOOL OF CHINESE MEDICINE

Researcher : Cai X

List of Research Outputs

Cai X., 祛風勝濕通絡法治療慢性腎炎蛋白尿30例臨床觀察, 中國中西醫結合腎臟病雜誌, 2011, 2.

Researcher : Cao K

List of Research Outputs

Chen R.Q., Wong C.M., Cao K. and Lam T.H., An evidence-based validation of traditional Chinese medicine syndromes, Complementary Therapies in Medicine . 2010, 18(5): 199-205.

Researcher : Chen J

Project Title:	Effects and Mechanisms of Litchi seed Extracts against Lung Specific Metastasis of Breast Cancer
Investigator(s):	Chen J, Guan X
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	04/2009
Completion Date:	03/2011

Project Title:	*Molecular mechanisms of natural LDH-A inhibitors from Spatholobus suberectus* inducing mitochondrial pathway apoptosis**
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Travel Grants for NSFC/RGC JRS
Start Date:	12/2009

Project Title:	Mechanism exploration of increased intracellular level of ROS in inhibiting breast caner growth and metastasis caused by Spatholobus suberectus
Investigator(s):	Chen J, Guan X, Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	01/2010
Completion Date:	01/2012

Project Title:	Exploration of active components from Spatholobus suberectus for treating breast cancer and preventing its recurrence and metastasis
Investigator(s):	Chen J, Guan X, Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Applied Research
Start Date:	02/2010
Completion Date:	05/2011

Project Title:	49th Anniversary Year of Medicina Alternativa World Congress of Integrated Medicines 2011 A.D. Relationship between liver blood deficiency and female breast cancer in the view of the TCM”
Investigator(s):	Chen J
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	06/2011
Completion Date:	06/2011

Project Title:	Regulation Role and Mechanisms of LDH-A on Angiogenesis and VEGF Expression in Cancer Cells
Investigator(s):	Chen J, Guan X
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2011

List of Research Outputs

Chen J., dietary pattern relationship with Breast cancer, UUS, 2011.

Chen J., Loo T.Y. and Wang Z., A case-control study of the relationship between Dietary Patterns of TCM and the Risk of Breast Cancer in Hong Kong , OOTR. 2011.

Chen J., Li T.Y.J., Loo T.Y. and Wang Z., CORRELATIONAL STUDY ON THE FIVE PERSONALITIES AND BREAST CANCER, OOTR. 2011.

Chen J., Chiu S., Wang Z. and Loo T.Y., Prevention Strategies for Recurrence and Metastasis of Breast Cancer by Chinese Medicine, OOTR. 2011.

Chen J., Relationship between liver blood deficiency and female breast cancer in the view of the TCM, 49th World Congress of Integrated Medicine held in KuaIa Lumpur, Malaysia . malir, 2011.

Chen J., Relationship between liver blood deficiency and female breast cancer in the view of the TCM, the 49th World Congress of Integrated Medicine held in KuaIa Lumpur, Malaysia. 2011.

Chen J., Chiu S., Chok H. and Wang Z., revention Strategies for Recurrence and Metastasis of Breast Cancer by Chinese Medicine. Global Traditional Chinese Medicine, 2011.

Chen J., type of Editorship, Analytica Chimica Acta. 2011.

LIU J., Liu Z., Wang D., Li M., Wang S., Chen J., Wang Y. and yang D., Induction of apoptosis in K562 cells by dicyclohexylammonium salt of hyperforin through a mitochondrial-related path way., Chem Biol Interact. . 2011.

Shen J., Lee W.S., Chen J. and Yang D., Caveolin-3 Peptide Protects Cardiomyocytes from Apoptotic Cell Death via Preserving Superoxide Dismutase Activity and Inhibiting Caspase-3 Activation under Hypoxia-reoxygenation, American Journal of Biomedical Sciences. 2011, 3(2): 126-144.

Wang N., Wang Z., Loo T.Y. and Chen J., Ellagic Acid, a phenolic compound, exerts anti-angiogenesis effect through VEGF production and VEGFR-2 signaling pathway, OOTR. 2011.

Wang Z., Loo T.Y., Wang N., Chow Y. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By a Medicinal Herb: Sanguisorba officinalis L, 2011.

Wang Z., Wang D., LOO W., Cheng Y., Chen L., Shen J., Yang D., Chow L., Guan X. and Chen J., LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis , Breast cancer research and treatment . Epub, 2011, 2012: 131: 791-800.

Wang Z., Loo T.Y., Wang N. and Chen J., Proteomic Identification of Anti-cancer Proteins in Dioscin-treated Human Esophogeal Cancer Kyse510 cells, OOTR. 2011.

Wang Z., Wang D., Loo T.Y., Cheng Y., Chen L., Shen J., yang D., Chow L., Guan X. and Chen J., Spatholobus sub erectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint, 2010.

Zhai J., Liu Z., Li J., Chen J., Jiang L., Wang D., Yuan J., Shen J. and Yang D., Different mechanisms of cis-9,trans-11- and trans-10,cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells, Journal of Nutritional Biochemistry. 2010.

cheng Y., Wang Z., LIu H., Wang D. and Chen J., Total Flavonoids and its Anti-tumor Activities by Different Solvent Extract from Spatholobus sub erectus Dunn, 2011.

Researcher : Chen RQ

List of Research Outputs

Chen R.Q., Wong C.M., Cao K. and Lam T.H., An evidence-based validation of traditional Chinese medicine syndromes, Complementary Therapies in Medicine . 2010, 18(5): 199-205.

Researcher : Chen X

List of Research Outputs

Chen X. and Shen J., Buyang Huanwu Decoction can promote the proliferation of neural progenitor cell and neurogenesis induced by ischemia stroke via Jak2/stat3-hes1 crosstalk, XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET . 2011.

Chen X. and Shen J., Effects of Salvianolic acid B and its nanoparticle on scavenging peroxynitrite and protecting neuronal cells from oxidative stress: Application for cerberal ischemia-reperfusion injury, Gordon Research Conferences for Oxidative Stress & Disease-Emerging Research Areas in the Study of Oxidative Stress and Disease . 2011.

Zheng G., Zhao Z.M., Wang Y., Gu Y., Li Y., Chen X., Fu S. and Shen J., Meta-analysis of scalp acupuncture for acute hypertensive intracerebral hemorrhage., Journal of Alternative and Complementary Medicine . 2011, 17(4): 293-299.

Researcher : Chen X

List of Research Outputs

Researcher : Cheng LY

List of Research Outputs

Sze C.W., Tong Y., Ng T.B., Cheng L.Y. and Cheung H.P., Herba Epimedii: Anti-oxidative properties and its medical Implications, Molecules. 2010, 15: 7861-7870.

Sze C.W., Cheung H.P., Lai Y.M., Ip C.W., Cheng L.Y., Ng T.B. and Tong Y., The Compatibility of Individual Herbs in Erxian Decoction, an Anti-menopausal Herbal Formula, for Treating Osteoporosis, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Sze C.W., Ip C.W., Cheng L.Y., Chu S.M.E. and Cheung H.P., Synergistic Effects of Six Component Herbs from Erxian Decoction, a Chinese Medicine Formula for Treating Osteoporosis, BIT's 1st Annual World Congress of Endocrinology and Metabolism (WCE). Xiamen, 2011.

Researcher : Cheung HP

List of Research Outputs

Chu S.M.E., Sze C.W., Cheung H.P., Liu W.K. and Tong Y., Anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions in human colorectal cancer cells and xenograft models, Nature – Centro Nacional de Investigaciones Oncologicas (CNIO): Cancer Symposium on Frontiers in tumor progression, Madrid, Spain. 2010, 116.

Chu S.M.E., Sze C.W., Cheung H.P., Wong K.L., Liu Q., Ng T.B. and Tong Y., Differential effects of anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions on human colorectal cancer models, Journal of Ethnopharmacology. 2011, DOI: 10.1016/j.jep.2011.05.035.

Sze C.W., Tong Y., Ng T.B., Cheng L.Y. and Cheung H.P., Herba Epimedii: Anti-oxidative properties and its medical Implications, Molecules. 2010, 15: 7861-7870.

Sze C.W., Tong Y., Cheung H.P. and Chu S.M.E., Synergistic Effects of Tian-Xian Liquid (TXL) on Anti-tumorigenicity in vivo, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Sze C.W., Ng T.B., Cheung H.P., Chu S.M.E. and Tong Y., Synergistic effects of constituents of Tian-Xian Liquid (TXL) on anti-tumorigenicity in vitro and in vivo, 2010 International Conference on Integrative medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong. 2010, 69.

Sze C.W., Cheung H.P., Lai Y.M., Ip C.W., Cheng L.Y., Ng T.B. and Tong Y., The Compatibility of Individual Herbs in Erxian Decoction, an Anti-menopausal Herbal Formula, for Treating Osteoporosis, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Sze C.W., Cheung H.P., Wong K.L. and Lam L., Effect of Erxian Decoction and its Bioactive Fractions on Lipid Profile of Menopausal Rat Model, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Tong Y., Cheung H.P., Sze C.W., Lai Y.M., Yow C.M.N., Ng T.B., Lam L., Wong K.L. and Chu S.M.E., Pharmacological Effects of Erxian Decoction, a Chinese Medicinal Formula, in Relieving Menopausal Syndrome, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Sze C.W., Wong K.L., Liu W. .K., Ng T.B., Wong J.H., Cheung H.P., Yow M.L., Chu S.M.E., Liu Q., Hu K.Y., Tsang K.W. and Lee W.S., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, Integrative Cancer Therapies. 2011, 10: 58-69.

Tong Y., Sze C.W., Ip C.W., Cheng L.Y., Chu S.M.E. and Cheung H.P., Synergistic Effects of Six Component Herbs from Erxian Decoction, a Chinese Medicine Formula for Treating Osteoporosis, BIT's 1st Annual World Congress of Endocrinology and Metabolism (WCE). Xiamen, 2011.

Researcher : Cheung HP

List of Research Outputs

Sze C.W., Tong Y., Ng T.B., Cheng L.Y. and Cheung H.P., Herba Epimedii: Anti-oxidative properties and its medical Implications, Molecules. 2010, 15: 7861-7870.

Researcher : Chow OY

List of Research Outputs

Feng Y., Wang N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on anti-cancer and anti-liver fibrosis between bear bile and botanic Chinese medicines, 2010 international conference on integrate medicine against cancer cum 6th Pong Ding Yuen international symposium on traditional Chinese Medicine. 2010.

Wang N., Feng Y., Zhu M., Xie T.N., Su W., Chow O.Y., Zhang Y., Ng K.M., Leung C.H. and Tong Y., Chemical and biological analysis of active free and conjugated bile acids in animal bile by using HPLC-ELSD and MTT methods, Experimental and Therapeutic Medicine. 2011.

Researcher : Chu SME

Project Title:	Nature and Centro Nacional de Investigaciones Oncologicas (CNIO) Cancer Symposium "Frontiers in Tumor Progression" Anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions in human colorectal cancer cells and xenograft models
Investigator(s):	Chu SME
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	10/2010
Completion Date:	10/2010

List of Research Outputs

Bai D.Q., Yow C.M.N., Tan Y., Chu S.M.E. and Xu C.S., Photodynamic action of LED-activated nanoscale photosensitizer in nasopharyngeal carcinoma cells, Laser Physics. 2010, 20(2): 544-550.

Chu S.M.E., Sze C.W. and Tong Y., Anti-metastatic evaluation of Tian-Xian Liquid (TXL) and its bioactive fractions in human colorectal cancer cells and xenograft models, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Hong Kong. 2010, Abstract no.: 073.

Chu S.M.E., Sze C.W., Liu Q., Liu W.K. and Tong Y., Anti-metastatic evaluation of a Chinese medicinal herbal formulation on human ovarian cancer cells., 2010 International Conference on Integrative medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong. 2010, 68.

Chu S.M.E., Sze C.W., Cheung H.P., Liu W.K. and Tong Y., Anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions in human colorectal cancer cells and xenograft models, Nature – Centro Nacional de Investigaciones Oncologicas (CNIO): Cancer Symposium on Frontiers in tumor progression, Madrid, Spain. 2010, 116.

Chu S.M.E., Sze C.W., Cheung H.P., Wong K.L., Liu Q., Ng T.B. and Tong Y., Differential effects of anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions on human colorectal cancer models, Journal of Ethnopharmacology. 2011, DOI: 10.1016/j.jep.2011.05.035.

Liu Q., Tong Y., Sze C.W., Liu W.K., Lam L., Chu S.M.E. and Yow C.M., Tian Xian Liquid (TXL) induces apoptosis in HT-29 colon cancer cell in vitro and inhibits tumor growth in vivo, Chinese medicine. 2010, 5:25: 1-7.

Sze C.W., Tong Y., Yow C.M.N., Liu W.K., Ng T.B., Liu Q. and Chu S.M.E., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, 16th Hong Kong International Cancer Congress, HK and 6th Annual Meeting Centre for Cancer Research.. Hong Kong, 2010.

Sze C.W., Tong Y., Cheung H.P. and Chu S.M.E., Synergistic Effects of Tian-Xian Liquid (TXL) on Anti-tumorigenicity in vivo, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Sze C.W., Ng T.B., Cheung H.P., Chu S.M.E. and Tong Y., Synergistic effects of constituents of Tian-Xian Liquid (TXL) on anti-tumorigenicity in vitro and in vivo, 2010 International Conference on Integrative medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong. 2010, 69.

Tong Y., Cheung H.P., Sze C.W., Lai Y.M., Yow C.M.N., Ng T.B., Lam L., Wong K.L. and Chu S.M.E., Pharmacological Effects of Erxian Decoction, a Chinese Medicinal Formula, in Relieving Menopausal Syndrome, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Sze C.W., Wong K.L., Liu W. .K., Ng T.B., Wong J.H., Cheung H.P., Yow M.L., Chu S.M.E., Liu Q., Hu K.Y., Tsang K.W. and Lee W.S., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, Integrative Cancer Therapies. 2011, 10: 58-69.

Tong Y., Sze C.W., Ip C.W., Cheng L.Y., Chu S.M.E. and Cheung H.P., Synergistic Effects of Six Component Herbs from Erxian Decoction, a Chinese Medicine Formula for Treating Osteoporosis, BIT's 1st Annual World Congress of Endocrinology and Metabolism (WCE). Xiamen, 2011.

Researcher : Feng Y

Project Title:	Mechanism involved in inhibition of tumor cell invasion by berberine derived from Coptis
Investigator(s):	Feng Y, Ching YP, Sze CW, Tong Y, Tsao GSW
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	09/2008
Completion Date:	08/2010

Project Title:	The effects of berberine and its mechanism on angiogenesis in hepatocellular carcinoma in vitro and in vivo systems
Investigator(s):	Feng Y, Tong Y, Tsao GSW
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2009
Completion Date:	06/2011

Project Title:	The role of autophagy and mitochondrial apoptosis in berberine induced hepatocellular caricinoma cell death and its underlying mechanism
Investigator(s):	Feng Y, Tsao GSW
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	09/2009
Completion Date:	08/2011

Project Title:	15th World Congress on Advances in Oncology and 13th International Symposium on Molecular Medicine Interdisciplinary approaches in study of Chinese medicines: case of coptis
Investigator(s):	Feng Y
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	10/2010
Completion Date:	10/2010

List of Research Outputs

Feng Y., Wang N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on anti-cancer and anti-liver fibrosis between bear bile and botanic Chinese medicines, 2010 international conference on integrate medicine against cancer cum 6th Pong Ding Yuen international symposium on traditional Chinese Medicine. 2010.

Feng Y., Editorial Board member from January 2010 to December 2011, In: Yeung Hin Win, Chinese Medicine. BioMed Central, 2011.

Feng Y., Siu G.K.Y., Ye X., Wang N., Yuen R.M.F., Leung C.H., Tong Y. and Kobayashi S., Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats. , Chin Med. 2010, 5: 33.

Feng Y., Siu G.K.Y., Ye X., Wang N., Yuen M.F., Leung C.H., Tong Y. and Kobayashi S., Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats, Chinese Medicine. 2010, 5: 33.

Feng Y. and Tong Y., Integrate PBL and OSCE into Chinese Medicine program: a challenge ahead, Enhancing Learning Experiences in Higher Education: International Conference. 2010.

Feng Y., Wang N., Zhu M., Zhang Z.J., Tong Y. and Tsao G.S.W., Interdisciplinary approaches in study of Chinese medicines: case of coptis, 15th World Congress on Advances in Oncology and 13th International Symposium on Molecular Medicine. 2010.

Feng Y. and Tong Y., Quality Assurance of Outcome-Based Professional Training in Chinese Medicine Programme: Current Status and Challenges, Frontiers in Medical and Health Sciences Education - HKU 2010 Conference: Assuring Excellence in Medical and Health Sciences Education. 2010.

Feng Y., Recent Patents on Recent Patents on Food, Nutrition & Agriculture , In: Yibin Feng , Journal editor. USA, BENTHAM SCIENCE PUBLISHERS LTD., 2010.

Feng Y., Wang N., Zhu M., Tsao G.S.W., Feng Y.G. and Li H.Y., Recent progress on anticancer candidates in herbal medicinal products. Recent patent in Food, Nutrition & Agriculture. , Recent patent in Food, Nutrition & Agriculture. 2011.

Lin X., Ng T.B., Feng Y., Tong Y., Wong H., Li L., Mo F., Shaw P.C., Li M.Z., Sze C.W. and Zhang Y., Dendrobium Candidum extract increases the Expression of Aquaporin-5 in Labial Glands from patients with Sjögren’s Syndrome, Phytomedicine. 2011, 18: 194-198.

Tong Y., Feng Y. and Shen J., A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials., 6th Congress of the Asian Medical Education Association, Trends in Medical Education, March 23-26, 2011, Kuala Lumpur, Malaysia. 2011.

Wang N., Zhu M., Feng Y., Tong Y. and Tsao G.S.W., 3alpha,7beta-Dihydroxy-5beta-cholan -24-oic Acid N-(2-Sulfoethyl)amide alters the microRNAs expression and promotes cell migration of human hepatocellular carcinoma cells, International Journal of Cancer (Excellence in Oncology, 18-20 November 2010, Athens, Hilton, Greece). 2010.

Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, J Cell Biochem. 2010.

Wang N., Feng Y., Zhu M., Xie T.N., Su W., Chow O.Y., Zhang Y., Ng K.M., Leung C.H. and Tong Y., Chemical and biological analysis of active free and conjugated bile acids in animal bile by using HPLC-ELSD and MTT methods, Experimental and Therapeutic Medicine. 2011.

Wang N., Feng Y., Lau E.P.W., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W.W. and Tsao G.S.W., F-actin reorganization and inactivation of Rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration, Integrative Cancer Therapies. USA, SAGE, 2010.

Wang N., Zhu M., Feng Y., Pan W., Zhanf M., Hao X. and Liang G., Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signaling in human hepatocellular carcinoma cells. , British Journal of Pharmacology. 2011.

Wang N., Zhu M., Feng Y., Tong Y. and Tsao G.S.W., Tumor necrosis factor-α up-regulates the microRNA-21 expression and promotes cell migration in human hepatocellular carcinoma cells MHCC97-L, International Journal of Cancer (Excellence in Oncology, 18-20 November 2010, Athens, Hilton, Greece),. 2010.

Zhang Z., Tan Q.R., Tong Y., Wang X.Y., Wang H.H., Ho L.M., Wong H.K., Feng Y., Wang D., Ng R., McAlonan G.M., Wang C.Y. and Wong V.T., An Epidemiological Study of Concomitant Use of Chinese Medicine and Antipsychotics in Schizophrenic Patients: Implication for Herb-Drug Interaction, PLos One. 2011, 6 (2): e17239.

Zhong L., Feng Y., Shen J. and Tong Y., A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials. 6th Congress of the Asian Medical Education Association, Trends in Medical Education, March 23-26, 2011, Kuala Lumpur, Malaysia. 2011.

Zhu M., Wang N., Tsao G.S.W., Yuen R.M.F., Feng Y.G., Wan T.S.K., Man K. and Feng Y., Up-regulation of microRNAs, miR21 and miR23a, in human liver cancer cells treated with Coptidis Rhizome aqueous extract, Experimental and Therapeutic Medicine. 2011.

Researcher : Fu S

List of Research Outputs

Zheng G., Zhao Z.M., Wang Y., Gu Y., Li Y., Chen X., Fu S. and Shen J., Meta-analysis of scalp acupuncture for acute hypertensive intracerebral hemorrhage., Journal of Alternative and Complementary Medicine . 2011, 17(4): 293-299.

Researcher : Gu Y

List of Research Outputs

Gu Y., Dee C.M.A. and Shen J., Interaction of free radicals, matrix metalloproteinases and caveolin-1 impacts blood-brain barrier permeability in cerebral ischemia and reperfusion injury., Frontier in Bioscience. 2011, 3: 1216-1231.

Shen J., Lee W.S., Gu Y., Fung P.C.W. and Tong L., Ginkgo biloba extract (EGb 761) prevents apoptosis in hypoxia-reoxygenated cardiomyocytes: involvement of mitochondria-dependent caspase pathway, Chiense Medicine. 2011, 6: 8.

Shen J., Gu Y. and Li Y., Interaction of Caveolin-1, Nitric Oxide and Matrix Metalloproteinases Impacts on Blood Brain Barrier Disruption and Infarction in Cerebral Ischemia and Reperfusion Injury, Annual Meeting of Guangzhou, Hong Kong and Macau in Neurology 2011.

Zheng G., Zhao Z.M., Wang Y., Gu Y., Li Y., Chen X., Fu S. and Shen J., Meta-analysis of scalp acupuncture for acute hypertensive intracerebral hemorrhage., Journal of Alternative and Complementary Medicine . 2011, 17(4): 293-299.

Researcher : Hu KY

Project Title:	Quality Assessment of Chinese Medicine Formula, Erxian Decoction, by high-performance liquid chromatography coupled with diode array detector
Investigator(s):	Hu KY, Tong Y, Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	10/2008

Project Title:	The 6th World Congress of Chinese Medicine 2009 The International Spread Characteristics of Traditional Chinese Medicine
Investigator(s):	Hu KY
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	12/2009

List of Research Outputs

Tong Y., Sze C.W., Wong K.L., Liu W. .K., Ng T.B., Wong J.H., Cheung H.P., Yow M.L., Chu S.M.E., Liu Q., Hu K.Y., Tsang K.W. and Lee W.S., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, Integrative Cancer Therapies. 2011, 10: 58-69.

Researcher : Ip CW

List of Research Outputs

Sze C.W., Cheung H.P., Lai Y.M., Ip C.W., Cheng L.Y., Ng T.B. and Tong Y., The Compatibility of Individual Herbs in Erxian Decoction, an Anti-menopausal Herbal Formula, for Treating Osteoporosis, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Sze C.W., Ip C.W., Cheng L.Y., Chu S.M.E. and Cheung H.P., Synergistic Effects of Six Component Herbs from Erxian Decoction, a Chinese Medicine Formula for Treating Osteoporosis, BIT's 1st Annual World Congress of Endocrinology and Metabolism (WCE). Xiamen, 2011.

Researcher : Jiang J

List of Research Outputs

So Y.L., Zhang Y., Jiang J., Lin K.J. and Shen J., 量子化学计算法分析蒙古黄芪中部分黄酮类化合物抗氧化作用机制, 中国药科大学学报, 2011, 18: 1-6.

Xu W.C., Shen J. and Jiang J., Phytochemical and biological studies of the plants from the genus daphne., Chemistry & Biodiversity. 2011, 8: 1215-1233.

Researcher : Lam SS

List of Research Outputs

Lam S.S., 寒底.熱底的養生保健, 鯉魚門社會服務處, 2010.

Lam S.S., 關節痛及肩周炎的中醫治療, 鯉魚門社區服務處, 2010.

Researcher : Lau EPW

List of Research Outputs

Wang N., Feng Y., Lau E.P.W., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W.W. and Tsao G.S.W., F-actin reorganization and inactivation of Rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration, Integrative Cancer Therapies. USA, SAGE, 2010.

Researcher : Lee WS

List of Research Outputs

Shen J., Lee W.S., Chen J. and Yang D., Caveolin-3 Peptide Protects Cardiomyocytes from Apoptotic Cell Death via Preserving Superoxide Dismutase Activity and Inhibiting Caspase-3 Activation under Hypoxia-reoxygenation, American Journal of Biomedical Sciences. 2011, 3(2): 126-144.

Shen J., Lee W.S., Gu Y., Fung P.C.W. and Tong L., Ginkgo biloba extract (EGb 761) prevents apoptosis in hypoxia-reoxygenated cardiomyocytes: involvement of mitochondria-dependent caspase pathway, Chiense Medicine. 2011, 6: 8.

Tong Y., Sze C.W., Wong K.L., Liu W. .K., Ng T.B., Wong J.H., Cheung H.P., Yow M.L., Chu S.M.E., Liu Q., Hu K.Y., Tsang K.W. and Lee W.S., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, Integrative Cancer Therapies. 2011, 10: 58-69.

Researcher : Li L

Project Title:	Effect of acupuncturing different acupoints at different time on the melatonin level of normal mice
Investigator(s):	Li L
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	03/2008
Completion Date:	08/2010

Project Title:	Mechanistic study of circadian rhythm of tryptophan hydroxylase and serotonergic receptors involved in acupuncture analgesia
Investigator(s):	Li L, Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	02/2011

List of Research Outputs

Li L., Wang Z. and Lo K...C., ‘Poisonous drugs’ and ’Sweet drugs’- Analysis of the culture of drug classification in the “Yellow Emperor’s Internal Classic”, The 9th Meeting of The Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Li L. and Yau C...H., “Poisonous drugs” and “Sweet drugs”-- Analysis of the culture of drug classification in the “Yellow Emperor’s Internal Classic” , “毒藥”與“甘藥”——試析《黃帝內經》中藥物分類的文化內涵 , In: 《中醫藥通報》編輯部, 中醫藥通報, 中國廈門, 《中醫藥通報》編輯部, 2011, 10(2): 35-37.

Li L., Acupuncture Therapies in The Yellow Emperor's Internal Classic for Curing Psychiatric Syndromes, Hong Kong International Acupuncture Conference –Neurological and Mental Illness. Hong Kong, 2011.

Li L., 頭皮針與補瀉, 香港首屆頭針及特種針法研討會, 香港, 2010.

Li L. and Yau C...H..., 《難經‧七十五難》新解, 中醫藥通報, 中國廈門, 中國中醫藥學會，廈門市中醫藥學會中醫藥通報雜誌社, 2011, 10(1): 36-37.

Lin X., Ng T.B., Feng Y., Tong Y., Wong H., Li L., Mo F., Shaw P.C., Li M.Z., Sze C.W. and Zhang Y., Dendrobium Candidum extract increases the Expression of Aquaporin-5 in Labial Glands from patients with Sjögren’s Syndrome, Phytomedicine. 2011, 18: 194-198.

Lo K...C. and Li L., On “Heart Dpminating Blood and Vessels”, 試論“心主血脈”, In: 《河南中醫》編輯部, 河南中醫, 河南鄭州, 《河南中醫》編輯部, 2011, 31(5): 452-453.

Lo K...C. and Li L., 論中醫學“祛邪”理念的文化內涵, In: 《中醫研究》雜誌社, 中醫研究, 中國鄭州, 《中醫研究》雜誌社, 2010, 23 (12): 3-5.

Lo K...C. and Li L., 論中醫學“祛邪”理念的文化內涵, 中醫研究, 2010, 12(23): 3-5.

Lo K...C. and Li L., “女子胞”功能淺識, 光明中醫, 2010, 25(11): 2093~2094.

Researcher : Li TYJ

List of Research Outputs

Chen J., Li T.Y.J., Loo T.Y. and Wang Z., CORRELATIONAL STUDY ON THE FIVE PERSONALITIES AND BREAST CANCER, OOTR. 2011.

Researcher : Li Y

List of Research Outputs

Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating β-catenin expression, Neurochemistry International . 2011, 59(2): 114-121.

Shen J., Gu Y. and Li Y., Interaction of Caveolin-1, Nitric Oxide and Matrix Metalloproteinases Impacts on Blood Brain Barrier Disruption and Infarction in Cerebral Ischemia and Reperfusion Injury, Annual Meeting of Guangzhou, Hong Kong and Macau in Neurology 2011.

Zheng G., Zhao Z.M., Wang Y., Gu Y., Li Y., Chen X., Fu S. and Shen J., Meta-analysis of scalp acupuncture for acute hypertensive intracerebral hemorrhage., Journal of Alternative and Complementary Medicine . 2011, 17(4): 293-299.

Researcher : Lin X

List of Research Outputs

Lin X. and Zhang Y., Polysaccharides of Dendrobium Officinale Inhibit TNF-alpha Induced Apoptosis in A-253 Cell Line (Poster Presentation). Gorden Research Conference: Oxidative Stress & Disease, In: Lin X, Kalin Zhang YB, Organizer from Gorden Research Conference. March 13-18, 2011. Ventura, CA, USA.. 2011.

Lin X. and Zhang Y., Polysaccharides of Dendrobium officinale Restore the Abnormal Expression and Distribution of Aquaporin-5 in SjÖgren’s Syndrome Model, In: Lin X and Kalin Zhang YB, 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong.. 2010.

Song J., Lin X., Sze C.W., Tong Y., Wong N.S., Shaw P.C. and Zhang Y., Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells, In: Song JX, Lin X, Ricky NS Wong, Stephen CW Sze, Tong Y, Shaw PC, Zhang YB, Phytotherapy, 2011 Mar . 2011, 25(3): 435-443.

Sze C.W., Lin X., Song J., Tong Y., Choi Y.M., Wong K.C., Chung W.Y. and Zhang Y., Chrysotoxine, a novel bibenzyl compound isolated from Dendrobium species, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-B modulation. , In: Stephen Sze CW, Lin X, Song JX, Tong Y, Kavin Wong CK, Chung WY, Mandy Choi YM, and Kalin Zhang YB, 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong. . 2010.

Sze C.W., Lin X., Song J., Tong Y., Wong C.K., Chung W.Y., Choi Y.M. and Zhang Y., Novel Mechanisms: Components of Dendrobium Species that Promote Aquaporin-5 (AQP-5) Expression. , In: Stephen Sze CW, Lin X, Song JX, Tong Y, Kavin Wong CK, Chung WY, Mandy Choi YM, and Kalin Zhang YB. , 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong.. 2010.

Wong H., Ng T.B., Ho K.L., Lin X., Song J.X., Choi M.Y.M., Wong C.K., Chung W.Y., Sze C.W. and Zhang Y., DNA Microarray for Investigating the Mechanism of Antitumor Action of Dendrobim chrysanthum Components on Hepatoma HepG2 Cells, 2010 International Conference on Integrative Medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong, 2010.

Wong J.H., Ng T.B., Lin X., Song J., Choi Y.M., Chung W.Y. and Zhang Y., DNA Microarray for Investigating the Mechanism of Antitumor Action of Dendrobim chrysanthum Components on Hepatoma HepG2 Cells., In: Jack Ho Wong, Tzi Bun Ng, Lin Xiang, Song Ju Xian, Mandy Yuen Man Choi, Wong Chun Kit, Chung Wing Yan, Pang Chui Shaw, Kalin Yanbo Zhang., 2010 International Conference on Integrative Medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Nov 27 & 28, 2010. Cheung Kung Hai Conference Centre, LKS Faculty of Medicine, The University of Hong Kong. . 2010.

Researcher : Lin X

List of Research Outputs

Researcher : Liu C

Project Title:	6th Annual Rocky Mountain Bioinformatics Conference CADEG, a Set of Software Tools for High Resolution Identification of Potential Chromosomal Abnormalities
Investigator(s):	Liu C
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	12/2008

Researcher : Liu J

List of Research Outputs

Liu J., Wong W.K., Chan Y.S., Make T.Q., Ng T.B. and Zhang Y., Application of Genomics and Proteomics to Identify Bacterial Gene in Chinese Medicines Candidates for Quality Control., In: Liu Jing Yi, Wong Wai Kong, Mak Tsz Wan, Chan Yuen Shan, Stephen Sze Cho Wing, Ng Tzi Bun, Kalin Zhang Yanbo, The first International EMP(Earth Microbiome Project) Conference. Organized by The Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences (CAS). Jun 13-15, 2011. Sha Tou Jiao, Shenzhen, China. P85.. 2011.

Researcher : Liu Q

List of Research Outputs

Chu S.M.E., Sze C.W., Liu Q., Liu W.K. and Tong Y., Anti-metastatic evaluation of a Chinese medicinal herbal formulation on human ovarian cancer cells., 2010 International Conference on Integrative medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong. 2010, 68.

Chu S.M.E., Sze C.W., Cheung H.P., Wong K.L., Liu Q., Ng T.B. and Tong Y., Differential effects of anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions on human colorectal cancer models, Journal of Ethnopharmacology. 2011, DOI: 10.1016/j.jep.2011.05.035.

Hu Y.M., Wang Y.T., Sze C.W., Tsang K.W., Liu Q., Zhong L. and Tong Y., Identification of the major chemical constituents and their metabolites in rat plasma and various organs after oral administration of effective EXD fraction by liquid chromatography-mass spectrometry., Biomedical Chromatography. 2010, 24: 479-489.

Liu Q., Tong Y., Sze C.W., Liu W.K., Lam L., Chu S.M.E. and Yow C.M., Tian Xian Liquid (TXL) induces apoptosis in HT-29 colon cancer cell in vitro and inhibits tumor growth in vivo, Chinese medicine. 2010, 5:25: 1-7.

Sze C.W., Tong Y., Yow C.M.N., Liu W.K., Ng T.B., Liu Q. and Chu S.M.E., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, 16th Hong Kong International Cancer Congress, HK and 6th Annual Meeting Centre for Cancer Research.. Hong Kong, 2010.

Tong Y., Sze C.W., Wong K.L., Liu W. .K., Ng T.B., Wong J.H., Cheung H.P., Yow M.L., Chu S.M.E., Liu Q., Hu K.Y., Tsang K.W. and Lee W.S., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, Integrative Cancer Therapies. 2011, 10: 58-69.

Researcher : Loo TY

List of Research Outputs

Chen J., Loo T.Y. and Wang Z., A case-control study of the relationship between Dietary Patterns of TCM and the Risk of Breast Cancer in Hong Kong , OOTR. 2011.

Chen J., Li T.Y.J., Loo T.Y. and Wang Z., CORRELATIONAL STUDY ON THE FIVE PERSONALITIES AND BREAST CANCER, OOTR. 2011.

Chen J., Chiu S., Wang Z. and Loo T.Y., Prevention Strategies for Recurrence and Metastasis of Breast Cancer by Chinese Medicine, OOTR. 2011.

Wang N., Wang Z., Loo T.Y. and Chen J., Ellagic Acid, a phenolic compound, exerts anti-angiogenesis effect through VEGF production and VEGFR-2 signaling pathway, OOTR. 2011.

Wang Z., Loo T.Y., Wang N., Chow Y. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By a Medicinal Herb: Sanguisorba officinalis L, 2011.

Wang Z., Loo T.Y., Wang N. and Chen J., Proteomic Identification of Anti-cancer Proteins in Dioscin-treated Human Esophogeal Cancer Kyse510 cells, OOTR. 2011.

Wang Z., Wang D., Loo T.Y., Cheng Y., Chen L., Shen J., yang D., Chow L., Guan X. and Chen J., Spatholobus sub erectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint, 2010.

Researcher : Mo F

List of Research Outputs

Lin X., Ng T.B., Feng Y., Tong Y., Wong H., Li L., Mo F., Shaw P.C., Li M.Z., Sze C.W. and Zhang Y., Dendrobium Candidum extract increases the Expression of Aquaporin-5 in Labial Glands from patients with Sjögren’s Syndrome, Phytomedicine. 2011, 18: 194-198.

Mo F., Mo Feizhi，Deng Tietao. Formation of the System of the Properties of the Five Organs. World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica. 2010, 12(4):1-5. (accepted), 2010.

Researcher : Ng TB

List of Research Outputs

Liu J.Y., Wong W.K., Mak T.W., Chan Y.S., Sze C.W., Ng T.B. and Zhang Y., Application of Genomics and Proteomics to Identify Bacterial Gene in Chinese Medicines Candidates for Quality Control., The Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences (CAS). Shenzhen, 2011.

Sze C.W., Tong Y., Ng T.B., Cheng L.Y. and Cheung H.P., Herba Epimedii: Anti-oxidative properties and its medical Implications, Molecules. 2010, 15: 7861-7870.

Sze C.W., Cheung H.P., Lai Y.M., Ip C.W., Cheng L.Y., Ng T.B. and Tong Y., The Compatibility of Individual Herbs in Erxian Decoction, an Anti-menopausal Herbal Formula, for Treating Osteoporosis, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Cheung H.P., Sze C.W., Lai Y.M., Yow C.M.N., Ng T.B., Lam L., Wong K.L. and Chu S.M.E., Pharmacological Effects of Erxian Decoction, a Chinese Medicinal Formula, in Relieving Menopausal Syndrome, 13th World Congress on Menopause. Roma, 2011.

Wong H., Ng T.B., Ho K.L., Lin X., Song J.X., Choi M.Y.M., Wong C.K., Chung W.Y., Sze C.W. and Zhang Y., DNA Microarray for Investigating the Mechanism of Antitumor Action of Dendrobim chrysanthum Components on Hepatoma HepG2 Cells, 2010 International Conference on Integrative Medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong, 2010.

Researcher : Qi H

List of Research Outputs

Qi H., Tong Y., Lau A.S.Y. and Rong J., Neuroprotection by (Z)-ligustilide against oxygen and glucose deprivation/reperfusion injury: Involvement of heme oxygenase-1 induction via the activation of Nrf2 and PI3K/Akt pathways, The 14th Biennial International Amine Oxidase Workshop. 2010.

Qi H. and Rong J., Parallel activation of Nrf2 and PI3K/Akt pathways by Z-ligustilide enhances the survival of neuronal PC12 cells under oxygen and glucose deprivation: a role for heme oxygenase-1, The 9th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Qi H., Siu S.O., Chen Y., Han Y.F., Chu I.K., Tong Y., Lau A.S.Y. and Rong J., Senkyunolides reduce hydrogen peroxide-induced oxidative damage in human liver HepG2 cells via induction of heme oxygenase-1, Chemico-Biological Interactions. 2011, 183(3): 380-389.

Researcher : Qi H

List of Research Outputs

Researcher : Rong J

Project Title:	The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy
Investigator(s):	Rong J
Department:	Medical Faculty
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	10/2006

Project Title:	Synergistic induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) by Chinese medicines Radix Astragali and Radix Paeoniae Rubrae: Identification of the active compounds and their intracellular targets
Investigator(s):	Rong J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	04/2009
Completion Date:	08/2010

Project Title:	Inhibitory effect of gallic acid and caffeoyl glucose in combination on the proliferation of human liver cancer HepG2 cells: A role of leukotriene B4 12-hydroxydehydrogenase (LTB4DH)
Investigator(s):	Rong J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	05/2010
Completion Date:	04/2011

Project Title:	The 14th Biennial International Amine Oxidase Workshop Neuroprotection by (Z)-ligustilide against oxygen and glucose deprivation/reperfusion injury: Involvement of heme oxygenase-1 induction via the activation of Nrf2 and PI3K/Akt pathways
Investigator(s):	Rong J
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	07/2010
Completion Date:	07/2010

Project Title:	Synergistic neurotoxic effects of (Z)-ligustilide and dopamine in rat dopaminergic cell line PC12: Implications for the pathogenesis of Parkinson’s disease (PD)
Investigator(s):	Rong J
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	03/2011

List of Research Outputs

Cui W., Li W., Zhao Y., Mak S., Gao Y., Luo J., Zhang H., Liu Y., Carlier P.R., Rong J. and Han Y., Preventing H(2)O(2)-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone, Brain Research. London, UK, Elsevier, 2011, 1394: 14-23.

Qi H., Tong Y., Lau A.S.Y. and Rong J., Neuroprotection by (Z)-ligustilide against oxygen and glucose deprivation/reperfusion injury: Involvement of heme oxygenase-1 induction via the activation of Nrf2 and PI3K/Akt pathways, The 14th Biennial International Amine Oxidase Workshop. 2010.

Qi H. and Rong J., Parallel activation of Nrf2 and PI3K/Akt pathways by Z-ligustilide enhances the survival of neuronal PC12 cells under oxygen and glucose deprivation: a role for heme oxygenase-1, The 9th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Qi H., Siu S.O., Chen Y., Han Y.F., Chu I.K., Tong Y., Lau A.S.Y. and Rong J., Senkyunolides reduce hydrogen peroxide-induced oxidative damage in human liver HepG2 cells via induction of heme oxygenase-1, Chemico-Biological Interactions. 2011, 183(3): 380-389.

Wei L., Liu J., Le X.C., Han Y., Tong Y., Lau A.S.Y. and Rong J., Pharmacological induction of leukotriene B4-12-hydroxydehydrogenase suppresses the oncogenic transformation of human hepatoma HepG2 cells, International Journal of Oncology. Athens, Greece, Spandidos Publications Ltd, 2011, 39: 735-745.

Researcher : Shen J

Project Title:	Biochemical Society Meeting 679 University of Essex UK - Stress, Signalling and Control Reactive Oxygen Species Mediate Intracellular Cholesterol Accumulation via Modulating Caveolin-1 Pathway in Chinese Hamster Ovary Cells
Investigator(s):	Shen J
Department:	Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	07/2003

Project Title:	Interactions of Reactive Nitrogen Species, Caveolins and Matrix Metalloproteinases: A Novel Signal Mechanism in Disruption of Blood Brain Barrier during Ischemic Stroke
Investigator(s):	Shen J, Chung SK, So KF, Yang D
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	09/2008

Project Title:	Elucidating Effects and Mechanisms of Isoflavonoids from Astragalus Mongholicus in Improving Neurogenesis for Post-stroke Treatment
Investigator(s):	Shen J, Fu S
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	01/2010
Completion Date:	12/2010

Project Title:	Development of Hydroxysafflor Yellow A (HSYA) as a Botanical Drug for Reducing Blood Brain Barrier Permeability and Preventing Infarction Enlargement in Stroke Treatment
Investigator(s):	Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Applied Research
Start Date:	06/2010
Completion Date:	06/2011

Project Title:	Elucidating caveolin-1 as a negative modulating protein for proliferation of neural stem/progenitor cells and neural differentiation in post-ischemic brain
Investigator(s):	Shen J, Chung SK, So KF
Department:	School of Chinese Medicine
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	09/2010

Project Title:	7th World Stroke Congress Interaction of caveolin-1, nitric oxide and matrix metalloproteinases impacts on blood brain barrier disruption and infarction enlargement in cerebral ischemia-reperfusion injury
Investigator(s):	Shen J
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	10/2010
Completion Date:	10/2010

Project Title:	Effects of reactive nitrogen species inhibitors on preventing thrombolysis-induced blood brain barrier disruption and hemorrhagic transformation in cerebral ischemia-reperfusion injury
Investigator(s):	Shen J, Yang D, Liu KJ
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	04/2011

List of Research Outputs

Chen X. and Shen J., Buyang Huanwu Decoction can promote the proliferation of neural progenitor cell and neurogenesis induced by ischemia stroke via Jak2/stat3-hes1 crosstalk, XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET . 2011.

Chen X. and Shen J., Effects of Salvianolic acid B and its nanoparticle on scavenging peroxynitrite and protecting neuronal cells from oxidative stress: Application for cerberal ischemia-reperfusion injury, Gordon Research Conferences for Oxidative Stress & Disease-Emerging Research Areas in the Study of Oxidative Stress and Disease . 2011.

Gu Y., Dee C.M.A. and Shen J., Interaction of free radicals, matrix metalloproteinases and caveolin-1 impacts blood-brain barrier permeability in cerebral ischemia and reperfusion injury., Frontier in Bioscience. 2011, 3: 1216-1231.

Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating β-catenin expression, Neurochemistry International . 2011, 59(2): 114-121.

Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 promote astroglial differentiation of neural stem/progenitor cells through modulating Notch1/NICD and Hes1 expressions, Biochemical and Biophysical Research Communications. 2011, 407: 517-524.

Shen J., Interaction of caveolin-1, nitric oxide and matrix metalloproteinases impacts on blood brain barrier disruption and infarction enlargement in cerebral ischemia-reperfusion injury., 7th World Stroke Conference, Seoul, Kerea. 2010.

Shen J., 2. Cancer Stem Cells: Implications for Novel Drug Development and Understanding Therapeutic Principles of Chinese Herbal Medicine for Cancer Treatment., Shanghai International Integrative Medicine Congress. Shanghai, China. 2011.

Shen J., Acupuncture for post-stroke rehabilitation: insights from neurobiological progress, neuroimaging evidence and clinical prospective. Hong Kong Acupuncture International Conference, Neurological and Mental Illness, , HKAIC 2011, January 17-19, Hong Kong, China . 2011.

Shen J., Ad Hoc Reviewer for Neurochemistry International, BBRC, PLoS One, International Journal of Radiation Biology, Aging, Brain Research, Acta Pharmacologica Sinica, Pharmaceutical Biology etc.. 2011.

Shen J., Lee W.S., Chen J. and Yang D., Caveolin-3 Peptide Protects Cardiomyocytes from Apoptotic Cell Death via Preserving Superoxide Dismutase Activity and Inhibiting Caspase-3 Activation under Hypoxia-reoxygenation, American Journal of Biomedical Sciences. 2011, 3(2): 126-144.

Shen J., Drug discovery from herbal medicine for post-stroke treatment: Where we are? Where we go? , International Symposium on Exploration and Utilization of the Medicinal Plant Resources from Qinling Mountains.. 2011.

Shen J., Editorial Board, American Journal of Biomedical Sciences. 2011.

Shen J., Exploration of Active Components from a Classic TCM Formula for Post-stroke Neurogenesis ___A New Approach for Drug Discovery from Herbal Medicine , 從經典複方研究促中風後神經再生的活性組分 ----中藥複方發展新藥的新途徑 , 2010.

Shen J., Lee W.S., Gu Y., Fung P.C.W. and Tong L., Ginkgo biloba extract (EGb 761) prevents apoptosis in hypoxia-reoxygenated cardiomyocytes: involvement of mitochondria-dependent caspase pathway, Chiense Medicine. 2011, 6: 8.

Shen J., Gu Y. and Li Y., Interaction of Caveolin-1, Nitric Oxide and Matrix Metalloproteinases Impacts on Blood Brain Barrier Disruption and Infarction in Cerebral Ischemia and Reperfusion Injury, Annual Meeting of Guangzhou, Hong Kong and Macau in Neurology 2011.

Shen J., Interactions of caveolin-1 and nitric oxide impacts on regulating oxidative stress and blood brain barrier permeability during cerebral ischemia-reperfusion injury, Oxidative Stress & Disease: Emerging Research Areas in the Study of Oxidative Stress and Disease. 2011.

Shen J., Interactions of caveolin-1 and reactive nitrogen species: A novel signal pathway on regulating oxidative stress and blood brain barrier permeability during cere ischemia-reperfusion injury, 氧化壓力與退化性疾病之代謝體學研究研討會暨第四屆海峽兩岸三地自由基生物學與自由基醫學研討會. 台北桃園縣, 2010.

Shen J., Translational medicine and drug discovery from Chinese medicine for psot-stroke treatment , The 2nd Macoa Forum on Chinese Medical Sciences. 2010.

Shen J., 传统医学在老年医学中的应用与发展趋势, 首届老年医疗创新服务模式研讨会, Shenzhen, 2010.

So Y.L., Zhang Y., Jiang J., Lin K.J. and Shen J., 量子化学计算法分析蒙古黄芪中部分黄酮类化合物抗氧化作用机制, 中国药科大学学报, 2011, 18: 1-6.

Tong Y., Feng Y. and Shen J., A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials., 6th Congress of the Asian Medical Education Association, Trends in Medical Education, March 23-26, 2011, Kuala Lumpur, Malaysia. 2011.

Wang Z., Wang D., LOO W., Cheng Y., Chen L., Shen J., Yang D., Chow L., Guan X. and Chen J., LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis , Breast cancer research and treatment . Epub, 2011, 2012: 131: 791-800.

Wang Z., Wang D., Loo T.Y., Cheng Y., Chen L., Shen J., yang D., Chow L., Guan X. and Chen J., Spatholobus sub erectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint, 2010.

Xu M. and Shen J., Baicalin Protects Neural Cells from Cerebral Ischemia Reperfusion Injury by Scavenging Peroxynitrite, GRC Conference on Oxidative Stress & Disease . 2011.

Xu W.C., Shen J. and Jiang J., Phytochemical and biological studies of the plants from the genus daphne., Chemistry & Biodiversity. 2011, 8: 1215-1233.

Xu Y.C., Yang Y., Du L.B., Shen J., Wang G.Q., He Z., Tian Q. and Liu Y., Autoxidation and prooxidation mechanism of Danshensu, ACTA PHYSICO-CHIMICA SINICA . 2010, 26(7): 1737-1741.

Zhai J., Liu Z., Li J., Chen J., Jiang L., Wang D., Yuan J., Shen J. and Yang D., Different mechanisms of cis-9,trans-11- and trans-10,cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells, Journal of Nutritional Biochemistry. 2010.

Zheng G., Zhao Z.M., Wang Y., Gu Y., Li Y., Chen X., Fu S. and Shen J., Meta-analysis of scalp acupuncture for acute hypertensive intracerebral hemorrhage., Journal of Alternative and Complementary Medicine . 2011, 17(4): 293-299.

Zhong L., Feng Y., Shen J. and Tong Y., A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials. 6th Congress of the Asian Medical Education Association, Trends in Medical Education, March 23-26, 2011, Kuala Lumpur, Malaysia. 2011.

Researcher : Siu GKY

List of Research Outputs

Feng Y., Siu G.K.Y., Ye X., Wang N., Yuen R.M.F., Leung C.H., Tong Y. and Kobayashi S., Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats. , Chin Med. 2010, 5: 33.

Feng Y., Siu G.K.Y., Ye X., Wang N., Yuen M.F., Leung C.H., Tong Y. and Kobayashi S., Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats, Chinese Medicine. 2010, 5: 33.

Researcher : Song J

List of Research Outputs

Song J., Wong R.N.S., Sze C.W., Tong Y., Shaw P.C., Yao X.S. and Zhang Y., Chrysotoxine, a Novel compound, from Chinese Herb Inhibits 6-hydroxydopamine Induced apoptosis in SH-SY5Y Cells via Mitochondria protection and NF-B modulation. Alzheimer’s Disease Conference 2011: From Public Health, Basic and Clinical Sciences to Therapeutic Insights. , In: Ju-Xian Song, Ricky Ngok-Shun Wong, Cho-Wing Sze, Yao Tong, Pang-Chui Shaw, Xin-Sheng Yao, Yan-Bo Zhang., 26-27 May 2011. Organized by the Alzheimer’s Disease Research Network, SRT Healthy Aging, & Research Centre Of Heart, Brain, Hormone & Healthy Aging, The University of Hong Kong. 21 Sassoon Road, Hong Kong.. 2011.

Song J., Sze C.W. and Zhang Y., Chrysotoxine, a novel bibenzyl compound, inhibits 6-OHDA and MPP+, but not rotenone induced cell death in SH-SY5Y cells: anti-apoptotic and pro-survival mechanism, In: Juxian Song, Cho-Wing Sze, Yanbo Zhang., Gorden Research Conference: Oxidative Stress & Disease. Organizer from Gorden Research Conference. March 13-18, 2011. Ventura, CA, USA. Session 2, No.26.. 2011.

Song J., Shaw P.C., Sze C.W., Tong Y., Yao X.S., Ng T.B. and Zhang Y., Chrysotoxine, a novel bibenzyl compound, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-kappaB modulation, In: Song JX, Shaw PC, Sze CW, Tong Y, Yao XS, Ng TB, Zhang YB , Neurochem Int. 2010 Nov published. 2010, 57(6): 676-689.

Song J., Lin X., Sze C.W., Tong Y., Wong N.S., Shaw P.C. and Zhang Y., Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells, In: Song JX, Lin X, Ricky NS Wong, Stephen CW Sze, Tong Y, Shaw PC, Zhang YB, Phytotherapy, 2011 Mar . 2011, 25(3): 435-443.

Sze C.W., Lin X., Song J., Tong Y., Choi Y.M., Wong K.C., Chung W.Y. and Zhang Y., Chrysotoxine, a novel bibenzyl compound isolated from Dendrobium species, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-B modulation. , In: Stephen Sze CW, Lin X, Song JX, Tong Y, Kavin Wong CK, Chung WY, Mandy Choi YM, and Kalin Zhang YB, 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong. . 2010.

Sze C.W., Lin X., Song J., Tong Y., Wong C.K., Chung W.Y., Choi Y.M. and Zhang Y., Novel Mechanisms: Components of Dendrobium Species that Promote Aquaporin-5 (AQP-5) Expression. , In: Stephen Sze CW, Lin X, Song JX, Tong Y, Kavin Wong CK, Chung WY, Mandy Choi YM, and Kalin Zhang YB. , 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong.. 2010.

Wong J.H., Ng T.B., Lin X., Song J., Choi Y.M., Chung W.Y. and Zhang Y., DNA Microarray for Investigating the Mechanism of Antitumor Action of Dendrobim chrysanthum Components on Hepatoma HepG2 Cells., In: Jack Ho Wong, Tzi Bun Ng, Lin Xiang, Song Ju Xian, Mandy Yuen Man Choi, Wong Chun Kit, Chung Wing Yan, Pang Chui Shaw, Kalin Yanbo Zhang., 2010 International Conference on Integrative Medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Nov 27 & 28, 2010. Cheung Kung Hai Conference Centre, LKS Faculty of Medicine, The University of Hong Kong. . 2010.

Researcher : Song J

List of Research Outputs

Researcher : Sun S

List of Research Outputs

Sun S., 微針療法與臨床應用, 2010.

Researcher : Sze CW

Project Title:	Bioactive components of Tian Xian Liquid as a potential drug candidate for the treatment of colon cancer
Investigator(s):	Sze CW, Tong Y, Hu KY
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Applied Research
Start Date:	03/2009
Completion Date:	08/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CW, Zhang Y, Tong Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Support Programme (Tier 2)
Start Date:	12/2009

Project Title:	Proteomic study on ovary during menopausal transition
Investigator(s):	Sze CW, Tong Y, Zhang Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	01/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	02/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	02/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	07/2010

Project Title:	A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):	Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Innovation and Technology Fund Internship Programme
Start Date:	09/2010

Project Title:	Study of Novel Biomarkers for Authenticating the Age of Oriental Ginseng, Chinese Medicinal Herb, using Proteomics Approach
Investigator(s):	Sze CW, Tong Y, Zhang Y
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Applied Research
Start Date:	05/2011

Project Title:	Characterization of a tissue-selective aromatase modifier: implication for estrogen deficiency diseases
Investigator(s):	Sze CW, Tong Y, Lee CKF
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2011

Project Title:	13th World Congress on Menopause The Compatibility of Individual Herbs in Erxian Decoction, an Anti-menopausal Herbal Formula, for Treating Osteoporosis
Investigator(s):	Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	06/2011
Completion Date:	06/2011

List of Research Outputs

Chu S.M.E., Sze C.W. and Tong Y., Anti-metastatic evaluation of Tian-Xian Liquid (TXL) and its bioactive fractions in human colorectal cancer cells and xenograft models, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Hong Kong. 2010, Abstract no.: 073.

Chu S.M.E., Sze C.W., Liu Q., Liu W.K. and Tong Y., Anti-metastatic evaluation of a Chinese medicinal herbal formulation on human ovarian cancer cells., 2010 International Conference on Integrative medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong. 2010, 68.

Chu S.M.E., Sze C.W., Cheung H.P., Liu W.K. and Tong Y., Anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions in human colorectal cancer cells and xenograft models, Nature – Centro Nacional de Investigaciones Oncologicas (CNIO): Cancer Symposium on Frontiers in tumor progression, Madrid, Spain. 2010, 116.

Chu S.M.E., Sze C.W., Cheung H.P., Wong K.L., Liu Q., Ng T.B. and Tong Y., Differential effects of anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions on human colorectal cancer models, Journal of Ethnopharmacology. 2011, DOI: 10.1016/j.jep.2011.05.035.

Hu Y.M., Wang Y.T., Sze C.W., Tsang K.W., Liu Q., Zhong L. and Tong Y., Identification of the major chemical constituents and their metabolites in rat plasma and various organs after oral administration of effective EXD fraction by liquid chromatography-mass spectrometry., Biomedical Chromatography. 2010, 24: 479-489.

Lin X., Ng T.B., Feng Y., Tong Y., Wong H., Li L., Mo F., Shaw P.C., Li M.Z., Sze C.W. and Zhang Y., Dendrobium Candidum extract increases the Expression of Aquaporin-5 in Labial Glands from patients with Sjögren’s Syndrome, Phytomedicine. 2011, 18: 194-198.

Liu J.Y., Wong W.K., Mak T.W., Chan Y.S., Sze C.W., Ng T.B. and Zhang Y., Application of Genomics and Proteomics to Identify Bacterial Gene in Chinese Medicines Candidates for Quality Control., The Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences (CAS). Shenzhen, 2011.

Liu Q., Tong Y., Sze C.W., Liu W.K., Lam L., Chu S.M.E. and Yow C.M., Tian Xian Liquid (TXL) induces apoptosis in HT-29 colon cancer cell in vitro and inhibits tumor growth in vivo, Chinese medicine. 2010, 5:25: 1-7.

Ng T.B., Ye X.J., Wong J.H., Fang E.F., Chan Y.S., Pan W., Ye X.Y., Sze C.W., Zhang Y. and Wang H.X., Glyceolin, a soybean phytoalexin with medicinal properties, In: Ng TB, Ye XJ, Wong JH, Fang EF, Chan YS, Pan W, Ye XY, Sze SC, Zhang KY, Liu F, Wang HX, Appl Microbiol Biotechnol, 2011 Apr published. 2011, 90(1): 59-68.

Song J., Wong R.N.S., Sze C.W., Tong Y., Shaw P.C., Yao X.S. and Zhang Y., Chrysotoxine, a Novel compound, from Chinese Herb Inhibits 6-hydroxydopamine Induced apoptosis in SH-SY5Y Cells via Mitochondria protection and NF-B modulation. Alzheimer’s Disease Conference 2011: From Public Health, Basic and Clinical Sciences to Therapeutic Insights. , In: Ju-Xian Song, Ricky Ngok-Shun Wong, Cho-Wing Sze, Yao Tong, Pang-Chui Shaw, Xin-Sheng Yao, Yan-Bo Zhang., 26-27 May 2011. Organized by the Alzheimer’s Disease Research Network, SRT Healthy Aging, & Research Centre Of Heart, Brain, Hormone & Healthy Aging, The University of Hong Kong. 21 Sassoon Road, Hong Kong.. 2011.

Song J., Sze C.W. and Zhang Y., Chrysotoxine, a novel bibenzyl compound, inhibits 6-OHDA and MPP+, but not rotenone induced cell death in SH-SY5Y cells: anti-apoptotic and pro-survival mechanism, In: Juxian Song, Cho-Wing Sze, Yanbo Zhang., Gorden Research Conference: Oxidative Stress & Disease. Organizer from Gorden Research Conference. March 13-18, 2011. Ventura, CA, USA. Session 2, No.26.. 2011.

Song J., Shaw P.C., Sze C.W., Tong Y., Yao X.S., Ng T.B. and Zhang Y., Chrysotoxine, a novel bibenzyl compound, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-kappaB modulation, In: Song JX, Shaw PC, Sze CW, Tong Y, Yao XS, Ng TB, Zhang YB , Neurochem Int. 2010 Nov published. 2010, 57(6): 676-689.

Song J., Lin X., Sze C.W., Tong Y., Wong N.S., Shaw P.C. and Zhang Y., Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells, In: Song JX, Lin X, Ricky NS Wong, Stephen CW Sze, Tong Y, Shaw PC, Zhang YB, Phytotherapy, 2011 Mar . 2011, 25(3): 435-443.

Sze C.W., Lin X., Song J., Tong Y., Choi Y.M., Wong K.C., Chung W.Y. and Zhang Y., Chrysotoxine, a novel bibenzyl compound isolated from Dendrobium species, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-B modulation. , In: Stephen Sze CW, Lin X, Song JX, Tong Y, Kavin Wong CK, Chung WY, Mandy Choi YM, and Kalin Zhang YB, 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong. . 2010.

Sze C.W., Current Research Status of Erxian Decoction, a Chinese medicine formula, for relieving menopausal syndrome, TCM Workshop, the University of Hong Kong. Hong Kong, 2010.

Sze C.W. and Tong Y., Current Research Status of Erxian Decoction, a Chinese medicine formula, for relieving menopausal syndrome, TCM Workshop, the University of Hong Kong. Hong Kong, 2010.

Sze C.W. and Tong Y., GRF Incentive Awards to Principal Investigator. No 10209047., Donation from the Li Ka Shing Foundation: Enhanced CERG Top-Up Grants.. 2010.

Sze C.W., Tong Y., Ng T.B., Cheng L.Y. and Cheung H.P., Herba Epimedii: Anti-oxidative properties and its medical Implications, Molecules. 2010, 15: 7861-7870.

Sze C.W., Lin X., Song J., Tong Y., Wong C.K., Chung W.Y., Choi Y.M. and Zhang Y., Novel Mechanisms: Components of Dendrobium Species that Promote Aquaporin-5 (AQP-5) Expression. , In: Stephen Sze CW, Lin X, Song JX, Tong Y, Kavin Wong CK, Chung WY, Mandy Choi YM, and Kalin Zhang YB. , 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong.. 2010.

Sze C.W., Tong Y., Yow C.M.N., Liu W.K., Ng T.B., Liu Q. and Chu S.M.E., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, 16th Hong Kong International Cancer Congress, HK and 6th Annual Meeting Centre for Cancer Research.. Hong Kong, 2010.

Sze C.W., Tong Y., Cheung H.P. and Chu S.M.E., Synergistic Effects of Tian-Xian Liquid (TXL) on Anti-tumorigenicity in vivo, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Sze C.W., Ng T.B., Cheung H.P., Chu S.M.E. and Tong Y., Synergistic effects of constituents of Tian-Xian Liquid (TXL) on anti-tumorigenicity in vitro and in vivo, 2010 International Conference on Integrative medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong. 2010, 69.

Sze C.W., Cheung H.P., Lai Y.M., Ip C.W., Cheng L.Y., Ng T.B. and Tong Y., The Compatibility of Individual Herbs in Erxian Decoction, an Anti-menopausal Herbal Formula, for Treating Osteoporosis, 13th World Congress on Menopause. Roma, 2011.

Sze C.W., 中藥蛋白的研究與應用, 大公報, 2010.

Tong Y., Sze C.W., Cheung H.P., Wong K.L. and Lam L., Effect of Erxian Decoction and its Bioactive Fractions on Lipid Profile of Menopausal Rat Model, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Tong Y., Cheung H.P., Sze C.W., Lai Y.M., Yow C.M.N., Ng T.B., Lam L., Wong K.L. and Chu S.M.E., Pharmacological Effects of Erxian Decoction, a Chinese Medicinal Formula, in Relieving Menopausal Syndrome, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Sze C.W., Wong K.L., Liu W. .K., Ng T.B., Wong J.H., Cheung H.P., Yow M.L., Chu S.M.E., Liu Q., Hu K.Y., Tsang K.W. and Lee W.S., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, Integrative Cancer Therapies. 2011, 10: 58-69.

Tong Y., Sze C.W., Ip C.W., Cheng L.Y., Chu S.M.E. and Cheung H.P., Synergistic Effects of Six Component Herbs from Erxian Decoction, a Chinese Medicine Formula for Treating Osteoporosis, BIT's 1st Annual World Congress of Endocrinology and Metabolism (WCE). Xiamen, 2011.

Wong H., Peng L., Jiang Y., Li Q., Wang H.X., Liu F., Sze C.W., Zhang Y., Lv X.X. and Ng T.B., Cordymin, an antifungal peptide from the medicinal fungus Cordyceps militaris, In: Jack Wong H, Lina Peng, Jiang Y, Li Q, Wang HX, Liu F, Stephen Sze CW, Kalin Zhang YB, Lv XX, Ng TB, Phytomedicine, 2011 May published. 2011, 18: 387-392.

Wong H., Ng T.B., Ho K.L., Lin X., Song J.X., Choi M.Y.M., Wong C.K., Chung W.Y., Sze C.W. and Zhang Y., DNA Microarray for Investigating the Mechanism of Antitumor Action of Dendrobim chrysanthum Components on Hepatoma HepG2 Cells, 2010 International Conference on Integrative Medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong, 2010.

Wong J.A.C.K., Ng T... .B.U.N., Wang H.E.X.I.A.N.G., Sze C.W., Zhang K. .Y.A.N.B.A.O., Li Q. and Lu X. .X.U., Cordymin, an antifungal peptide from the medicinal fungus Cordyceps militaris., Phytomedicine. 2011, 18: 387-392.

Zhang Y., Sze C.W. and Tong Y., GRF Incentive Awards to Principal Investigator. No 10208970., In: Kalin YB Zhang, Stephen CW Sze, Tong Yao, Donation from the Li Ka Shing Foundation. 2010.

Zhang Y., Tong Y. and Sze C.W., Industrialization Generation Artemisinin, a Specific Compound from Artemisia annua of Chinese Herb Against Malaria by Plant Cell Culture Project No. 201007160006, In: Zhang YB, Tong Yao, Sze CW., Seed Funding Programme for Basic Research from HKU. 2010.

Zhang Y., Sze C.W. and Ng T.B., PI: HK$100,000 (Dec 2010). Industrialization Generation Artemisinin, a Specific Compound from Artemisia annua of Chinese Herb Against Malaria by Plant Cell Culture. , In: Zhang YB, Sze CW, Ng TB., Seed Funding Programme for Basic Research from HKU. Project No. 201007160006. . 2011.

Zhang Y., Sze C.W. and Ng T.B., PI: HK$98,590 (Mar 2011). Investigation of the Mechanism of Aquaporin 5 in Pulmonary Inflammation., In: Zhang YB, Sze CW, Ng TB., Seed Funding Programme for Basic Research from HKU. Project No. 201011159206.. 2011.

Zhang Y., Sze C.W., Wong J.H., Ng T.B., Jiang Y., Liu F. and Cho S., Purification and Characterization of a Laccase with Inhibitory Activity toward HIV-1 Reverse Transcriptase and Tumor Cells from an Edible Mushroom (Pleurotus cornucopiae). , In: Wong JH, Ng TB, Jiang Y, Liu F, Cho S, Sze W, Zhang KY., Protein Pept Lett.. 2010, 17(8): 1040-1047.

Researcher : Tong Y

Project Title:	Mechanical Study of Tian Xian Liquid (TXL), Chinese Medicine Formula, in Treatment of Colon Cancer in vitro
Investigator(s):	Tong Y, Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	12/2008

Project Title:	A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials
Investigator(s):	Tong Y, Shen J, Zhong L, Diu CK
Department:	School of Chinese Medicine
Source(s) of Funding:	Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:	09/2009

Project Title:	An Innovative Approach for Research and Development of Novel Scientific Chinese Medicine Formula: Erxian Decoction for Relieving Menopause Syndrome as a Study Model
Investigator(s):	Tong Y, Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Applied Research
Start Date:	01/2010
Completion Date:	12/2010

Project Title:	A pilot study on the effects of a Chinese herbal formula on menopause
Investigator(s):	Tong Y, Chu SME, Zhong L
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	01/2010
Completion Date:	12/2010

Project Title:	Mechanistic Study of Erxian Decoction on serum lipid profile of Menopausal Rat Model
Investigator(s):	Tong Y, Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Small Project Funding
Start Date:	12/2010

Project Title:	A pure chemical isolated from cortex phellodendri as a potential drug candidate for treating menopausal syndrome
Investigator(s):	Tong Y, Sze CW
Department:	School of Chinese Medicine
Source(s) of Funding:	Seed Funding Programme for Applied Research
Start Date:	06/2011

Project Title:	13th World Congress on Menopause Pharmacological Effects of Erxian Decoction, a Chinese Medicinal Formula, in Relieving Menopausal Syndrome
Investigator(s):	Tong Y
Department:	School of Chinese Medicine
Source(s) of Funding:	URC/CRCG - Conference Grants for Teaching Staff
Start Date:	06/2011
Completion Date:	06/2011

List of Research Outputs

Chu S.M.E., Sze C.W. and Tong Y., Anti-metastatic evaluation of Tian-Xian Liquid (TXL) and its bioactive fractions in human colorectal cancer cells and xenograft models, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Hong Kong. 2010, Abstract no.: 073.

Chu S.M.E., Sze C.W., Liu Q., Liu W.K. and Tong Y., Anti-metastatic evaluation of a Chinese medicinal herbal formulation on human ovarian cancer cells., 2010 International Conference on Integrative medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong. 2010, 68.

Chu S.M.E., Sze C.W., Cheung H.P., Liu W.K. and Tong Y., Anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions in human colorectal cancer cells and xenograft models, Nature – Centro Nacional de Investigaciones Oncologicas (CNIO): Cancer Symposium on Frontiers in tumor progression, Madrid, Spain. 2010, 116.

Chu S.M.E., Sze C.W., Cheung H.P., Wong K.L., Liu Q., Ng T.B. and Tong Y., Differential effects of anti-metastatic mechanism of Tian-Xian Liquid (TXL) and its bioactive fractions on human colorectal cancer models, Journal of Ethnopharmacology. 2011, DOI: 10.1016/j.jep.2011.05.035.

Feng Y., Wang N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on anti-cancer and anti-liver fibrosis between bear bile and botanic Chinese medicines, 2010 international conference on integrate medicine against cancer cum 6th Pong Ding Yuen international symposium on traditional Chinese Medicine. 2010.

Feng Y., Siu G.K.Y., Ye X., Wang N., Yuen R.M.F., Leung C.H., Tong Y. and Kobayashi S., Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats. , Chin Med. 2010, 5: 33.

Feng Y., Siu G.K.Y., Ye X., Wang N., Yuen M.F., Leung C.H., Tong Y. and Kobayashi S., Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats, Chinese Medicine. 2010, 5: 33.

Feng Y. and Tong Y., Integrate PBL and OSCE into Chinese Medicine program: a challenge ahead, Enhancing Learning Experiences in Higher Education: International Conference. 2010.

Feng Y., Wang N., Zhu M., Zhang Z.J., Tong Y. and Tsao G.S.W., Interdisciplinary approaches in study of Chinese medicines: case of coptis, 15th World Congress on Advances in Oncology and 13th International Symposium on Molecular Medicine. 2010.

Feng Y. and Tong Y., Quality Assurance of Outcome-Based Professional Training in Chinese Medicine Programme: Current Status and Challenges, Frontiers in Medical and Health Sciences Education - HKU 2010 Conference: Assuring Excellence in Medical and Health Sciences Education. 2010.

Hu Y.M., Wang Y.T., Sze C.W., Tsang K.W., Liu Q., Zhong L. and Tong Y., Identification of the major chemical constituents and their metabolites in rat plasma and various organs after oral administration of effective EXD fraction by liquid chromatography-mass spectrometry., Biomedical Chromatography. 2010, 24: 479-489.

Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 inhibits oligodendroglial differentiation of neural stem/progenitor cells through modulating β-catenin expression, Neurochemistry International . 2011, 59(2): 114-121.

Li Y., Lau W.M., So K.F., Tong Y. and Shen J., Caveolin-1 promote astroglial differentiation of neural stem/progenitor cells through modulating Notch1/NICD and Hes1 expressions, Biochemical and Biophysical Research Communications. 2011, 407: 517-524.

Lin X., Ng T.B., Feng Y., Tong Y., Wong H., Li L., Mo F., Shaw P.C., Li M.Z., Sze C.W. and Zhang Y., Dendrobium Candidum extract increases the Expression of Aquaporin-5 in Labial Glands from patients with Sjögren’s Syndrome, Phytomedicine. 2011, 18: 194-198.

Liu Q., Tong Y., Sze C.W., Liu W.K., Lam L., Chu S.M.E. and Yow C.M., Tian Xian Liquid (TXL) induces apoptosis in HT-29 colon cancer cell in vitro and inhibits tumor growth in vivo, Chinese medicine. 2010, 5:25: 1-7.

Qi H., Tong Y., Lau A.S.Y. and Rong J., Neuroprotection by (Z)-ligustilide against oxygen and glucose deprivation/reperfusion injury: Involvement of heme oxygenase-1 induction via the activation of Nrf2 and PI3K/Akt pathways, The 14th Biennial International Amine Oxidase Workshop. 2010.

Qi H., Siu S.O., Chen Y., Han Y.F., Chu I.K., Tong Y., Lau A.S.Y. and Rong J., Senkyunolides reduce hydrogen peroxide-induced oxidative damage in human liver HepG2 cells via induction of heme oxygenase-1, Chemico-Biological Interactions. 2011, 183(3): 380-389.

Song J., Wong R.N.S., Sze C.W., Tong Y., Shaw P.C., Yao X.S. and Zhang Y., Chrysotoxine, a Novel compound, from Chinese Herb Inhibits 6-hydroxydopamine Induced apoptosis in SH-SY5Y Cells via Mitochondria protection and NF-B modulation. Alzheimer’s Disease Conference 2011: From Public Health, Basic and Clinical Sciences to Therapeutic Insights. , In: Ju-Xian Song, Ricky Ngok-Shun Wong, Cho-Wing Sze, Yao Tong, Pang-Chui Shaw, Xin-Sheng Yao, Yan-Bo Zhang., 26-27 May 2011. Organized by the Alzheimer’s Disease Research Network, SRT Healthy Aging, & Research Centre Of Heart, Brain, Hormone & Healthy Aging, The University of Hong Kong. 21 Sassoon Road, Hong Kong.. 2011.

Song J., Shaw P.C., Sze C.W., Tong Y., Yao X.S., Ng T.B. and Zhang Y., Chrysotoxine, a novel bibenzyl compound, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-kappaB modulation, In: Song JX, Shaw PC, Sze CW, Tong Y, Yao XS, Ng TB, Zhang YB , Neurochem Int. 2010 Nov published. 2010, 57(6): 676-689.

Song J., Lin X., Sze C.W., Tong Y., Wong N.S., Shaw P.C. and Zhang Y., Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells, In: Song JX, Lin X, Ricky NS Wong, Stephen CW Sze, Tong Y, Shaw PC, Zhang YB, Phytotherapy, 2011 Mar . 2011, 25(3): 435-443.

Sze C.W., Lin X., Song J., Tong Y., Choi Y.M., Wong K.C., Chung W.Y. and Zhang Y., Chrysotoxine, a novel bibenzyl compound isolated from Dendrobium species, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-B modulation. , In: Stephen Sze CW, Lin X, Song JX, Tong Y, Kavin Wong CK, Chung WY, Mandy Choi YM, and Kalin Zhang YB, 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong. . 2010.

Sze C.W. and Tong Y., Current Research Status of Erxian Decoction, a Chinese medicine formula, for relieving menopausal syndrome, TCM Workshop, the University of Hong Kong. Hong Kong, 2010.

Sze C.W. and Tong Y., GRF Incentive Awards to Principal Investigator. No 10209047., Donation from the Li Ka Shing Foundation: Enhanced CERG Top-Up Grants.. 2010.

Sze C.W., Tong Y., Ng T.B., Cheng L.Y. and Cheung H.P., Herba Epimedii: Anti-oxidative properties and its medical Implications, Molecules. 2010, 15: 7861-7870.

Sze C.W., Lin X., Song J., Tong Y., Wong C.K., Chung W.Y., Choi Y.M. and Zhang Y., Novel Mechanisms: Components of Dendrobium Species that Promote Aquaporin-5 (AQP-5) Expression. , In: Stephen Sze CW, Lin X, Song JX, Tong Y, Kavin Wong CK, Chung WY, Mandy Choi YM, and Kalin Zhang YB. , 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 23-25, 2010. Hong Kong Convention & Exhibition Centre, Hong Kong.. 2010.

Sze C.W., Tong Y., Yow C.M.N., Liu W.K., Ng T.B., Liu Q. and Chu S.M.E., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, 16th Hong Kong International Cancer Congress, HK and 6th Annual Meeting Centre for Cancer Research.. Hong Kong, 2010.

Sze C.W., Tong Y., Cheung H.P. and Chu S.M.E., Synergistic Effects of Tian-Xian Liquid (TXL) on Anti-tumorigenicity in vivo, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Sze C.W., Ng T.B., Cheung H.P., Chu S.M.E. and Tong Y., Synergistic effects of constituents of Tian-Xian Liquid (TXL) on anti-tumorigenicity in vitro and in vivo, 2010 International Conference on Integrative medicine against Cancer Cum The 6th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. Hong Kong. 2010, 69.

Sze C.W., Cheung H.P., Lai Y.M., Ip C.W., Cheng L.Y., Ng T.B. and Tong Y., The Compatibility of Individual Herbs in Erxian Decoction, an Anti-menopausal Herbal Formula, for Treating Osteoporosis, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Feng Y. and Shen J., A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials., 6th Congress of the Asian Medical Education Association, Trends in Medical Education, March 23-26, 2011, Kuala Lumpur, Malaysia. 2011.

Tong Y. and Fang Z.H., Cancer Prevention: Comparison of Evidence of Chinese and Western Medicines, Chinese and Western Perspectives Conference. Hong Kong, 2011.

Tong Y., “體質養生”的意義及運用, Conference on Public Health and Preventive Medicine 2010, Public Health in the 21st Century – New Challenges and Strategies. Hong Kong, 2010.

Tong Y., Sze C.W., Cheung H.P., Wong K.L. and Lam L., Effect of Erxian Decoction and its Bioactive Fractions on Lipid Profile of Menopausal Rat Model, The 9th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Tong Y., Cheung H.P., Sze C.W., Lai Y.M., Yow C.M.N., Ng T.B., Lam L., Wong K.L. and Chu S.M.E., Pharmacological Effects of Erxian Decoction, a Chinese Medicinal Formula, in Relieving Menopausal Syndrome, 13th World Congress on Menopause. Roma, 2011.

Tong Y., Sze C.W., Wong K.L., Liu W. .K., Ng T.B., Wong J.H., Cheung H.P., Yow M.L., Chu S.M.E., Liu Q., Hu K.Y., Tsang K.W. and Lee W.S., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, Integrative Cancer Therapies. 2011, 10: 58-69.

Tong Y., Sze C.W., Ip C.W., Cheng L.Y., Chu S.M.E. and Cheung H.P., Synergistic Effects of Six Component Herbs from Erxian Decoction, a Chinese Medicine Formula for Treating Osteoporosis, BIT's 1st Annual World Congress of Endocrinology and Metabolism (WCE). Xiamen, 2011.

Tong Y., Trial Implementation of PBL Teaching in TCM Education in the University of Hong Kong, 1st Asian-Pacific Joint PBL Conference 2010, Inaugural APC-PBL and PAP-PHS joint Conference on PBL Satellite PBL Workshop. Taiwan, 2010.

Tong Y., 2010中國中醫藥年鑒, 上海中醫藥大學出版社, 2010.

Wang N., Zhu M., Feng Y., Tong Y. and Tsao G.S.W., 3alpha,7beta-Dihydroxy-5beta-cholan -24-oic Acid N-(2-Sulfoethyl)amide alters the microRNAs expression and promotes cell migration of human hepatocellular carcinoma cells, International Journal of Cancer (Excellence in Oncology, 18-20 November 2010, Athens, Hilton, Greece). 2010.

Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, J Cell Biochem. 2010.

Wang N., Feng Y., Zhu M., Xie T.N., Su W., Chow O.Y., Zhang Y., Ng K.M., Leung C.H. and Tong Y., Chemical and biological analysis of active free and conjugated bile acids in animal bile by using HPLC-ELSD and MTT methods, Experimental and Therapeutic Medicine. 2011.

Wang N., Feng Y., Lau E.P.W., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W.W. and Tsao G.S.W., F-actin reorganization and inactivation of Rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration, Integrative Cancer Therapies. USA, SAGE, 2010.

Wang N., Zhu M., Feng Y., Tong Y. and Tsao G.S.W., Tumor necrosis factor-α up-regulates the microRNA-21 expression and promotes cell migration in human hepatocellular carcinoma cells MHCC97-L, International Journal of Cancer (Excellence in Oncology, 18-20 November 2010, Athens, Hilton, Greece),. 2010.

Wei L., Liu J., Le X.C., Han Y., Tong Y., Lau A.S.Y. and Rong J., Pharmacological induction of leukotriene B4-12-hydroxydehydrogenase suppresses the oncogenic transformation of human hepatoma HepG2 cells, International Journal of Oncology. Athens, Greece, Spandidos Publications Ltd, 2011, 39: 735-745.

Zhang Y., Sze C.W. and Tong Y., GRF Incentive Awards to Principal Investigator. No 10208970., In: Kalin YB Zhang, Stephen CW Sze, Tong Yao, Donation from the Li Ka Shing Foundation. 2010.

Zhang Y., Tong Y. and Sze C.W., Industrialization Generation Artemisinin, a Specific Compound from Artemisia annua of Chinese Herb Against Malaria by Plant Cell Culture Project No. 201007160006, In: Zhang YB, Tong Yao, Sze CW., Seed Funding Programme for Basic Research from HKU. 2010.

Zhang Z., Tan Q.R., Tong Y., Wang X.Y., Wang H.H., Ho L.M., Wong H.K., Feng Y., Wang D., Ng R., McAlonan G.M., Wang C.Y. and Wong V.T., An Epidemiological Study of Concomitant Use of Chinese Medicine and Antipsychotics in Schizophrenic Patients: Implication for Herb-Drug Interaction, PLos One. 2011, 6 (2): e17239.

Zhong L., Feng Y., Shen J. and Tong Y., A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials. 6th Congress of the Asian Medical Education Association, Trends in Medical Education, March 23-26, 2011, Kuala Lumpur, Malaysia. 2011.

Zhong L. and Tong Y., Quality Assessment of the Clinical Trials with Chinese Medicine on Menopausal Syndrome in the Last Five Years: From the View of Evidence-based Medicine, 5th International Congress On Complementary Medicine Research. 2011, P-105.

Researcher : Tsang KW

List of Research Outputs

Hu Y.M., Wang Y.T., Sze C.W., Tsang K.W., Liu Q., Zhong L. and Tong Y., Identification of the major chemical constituents and their metabolites in rat plasma and various organs after oral administration of effective EXD fraction by liquid chromatography-mass spectrometry., Biomedical Chromatography. 2010, 24: 479-489.

Tong Y., Sze C.W., Wong K.L., Liu W. .K., Ng T.B., Wong J.H., Cheung H.P., Yow M.L., Chu S.M.E., Liu Q., Hu K.Y., Tsang K.W. and Lee W.S., Regulation of p21, MMP-1 and MDR-1 expression in Human colon carcinoma HT29 by Tian Xian Liquid, a Chinese Medicine Formula, in vitro and in vivo, Integrative Cancer Therapies. 2011, 10: 58-69.

Researcher : Wang N

List of Research Outputs

Feng Y., Wang N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on anti-cancer and anti-liver fibrosis between bear bile and botanic Chinese medicines, 2010 international conference on integrate medicine against cancer cum 6th Pong Ding Yuen international symposium on traditional Chinese Medicine. 2010.

Feng Y., Siu G.K.Y., Ye X., Wang N., Yuen R.M.F., Leung C.H., Tong Y. and Kobayashi S., Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats. , Chin Med. 2010, 5: 33.

Feng Y., Siu G.K.Y., Ye X., Wang N., Yuen M.F., Leung C.H., Tong Y. and Kobayashi S., Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats, Chinese Medicine. 2010, 5: 33.

Feng Y., Wang N., Zhu M., Zhang Z.J., Tong Y. and Tsao G.S.W., Interdisciplinary approaches in study of Chinese medicines: case of coptis, 15th World Congress on Advances in Oncology and 13th International Symposium on Molecular Medicine. 2010.

Feng Y., Wang N., Zhu M., Tsao G.S.W., Feng Y.G. and Li H.Y., Recent progress on anticancer candidates in herbal medicinal products. Recent patent in Food, Nutrition & Agriculture. , Recent patent in Food, Nutrition & Agriculture. 2011.

Wang N., Zhu M., Feng Y., Tong Y. and Tsao G.S.W., 3alpha,7beta-Dihydroxy-5beta-cholan -24-oic Acid N-(2-Sulfoethyl)amide alters the microRNAs expression and promotes cell migration of human hepatocellular carcinoma cells, International Journal of Cancer (Excellence in Oncology, 18-20 November 2010, Athens, Hilton, Greece). 2010.

Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, J Cell Biochem. 2010.

Wang N., Feng Y., Zhu M., Xie T.N., Su W., Chow O.Y., Zhang Y., Ng K.M., Leung C.H. and Tong Y., Chemical and biological analysis of active free and conjugated bile acids in animal bile by using HPLC-ELSD and MTT methods, Experimental and Therapeutic Medicine. 2011.

Wang N., Wang Z., Loo T.Y. and Chen J., Ellagic Acid, a phenolic compound, exerts anti-angiogenesis effect through VEGF production and VEGFR-2 signaling pathway, OOTR. 2011.

Wang N., Feng Y., Lau E.P.W., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W.W. and Tsao G.S.W., F-actin reorganization and inactivation of Rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration, Integrative Cancer Therapies. USA, SAGE, 2010.

Wang N., Zhu M., Feng Y., Pan W., Zhanf M., Hao X. and Liang G., Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signaling in human hepatocellular carcinoma cells. , British Journal of Pharmacology. 2011.

Wang N., Zhu M., Feng Y., Tong Y. and Tsao G.S.W., Tumor necrosis factor-α up-regulates the microRNA-21 expression and promotes cell migration in human hepatocellular carcinoma cells MHCC97-L, International Journal of Cancer (Excellence in Oncology, 18-20 November 2010, Athens, Hilton, Greece),. 2010.

Wang Z., Loo T.Y., Wang N., Chow Y. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By a Medicinal Herb: Sanguisorba officinalis L, 2011.

Wang Z., Loo T.Y., Wang N. and Chen J., Proteomic Identification of Anti-cancer Proteins in Dioscin-treated Human Esophogeal Cancer Kyse510 cells, OOTR. 2011.

Zhu M., Wang N., Tsao G.S.W., Yuen R.M.F., Feng Y.G., Wan T.S.K., Man K. and Feng Y., Up-regulation of microRNAs, miR21 and miR23a, in human liver cancer cells treated with Coptidis Rhizome aqueous extract, Experimental and Therapeutic Medicine. 2011.

Researcher : Wang N

List of Research Outputs

Wang N., Wang Z., Loo T.Y. and Chen J., Ellagic Acid, a phenolic compound, exerts anti-angiogenesis effect through VEGF production and VEGFR-2 signaling pathway, OOTR. 2011.

Wang Z., Loo T.Y., Wang N., Chow Y. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By a Medicinal Herb: Sanguisorba officinalis L, 2011.

Wang Z., Loo T.Y., Wang N. and Chen J., Proteomic Identification of Anti-cancer Proteins in Dioscin-treated Human Esophogeal Cancer Kyse510 cells, OOTR. 2011.

Researcher : Wang N

List of Research Outputs

Wang N., Wang Z., Loo T.Y. and Chen J., Ellagic Acid, a phenolic compound, exerts anti-angiogenesis effect through VEGF production and VEGFR-2 signaling pathway, OOTR. 2011.

Wang Z., Loo T.Y., Wang N., Chow Y. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By a Medicinal Herb: Sanguisorba officinalis L, 2011.

Wang Z., Loo T.Y., Wang N. and Chen J., Proteomic Identification of Anti-cancer Proteins in Dioscin-treated Human Esophogeal Cancer Kyse510 cells, OOTR. 2011.

Researcher : Wang Z

List of Research Outputs

Chen J., Loo T.Y. and Wang Z., A case-control study of the relationship between Dietary Patterns of TCM and the Risk of Breast Cancer in Hong Kong , OOTR. 2011.

Chen J., Li T.Y.J., Loo T.Y. and Wang Z., CORRELATIONAL STUDY ON THE FIVE PERSONALITIES AND BREAST CANCER, OOTR. 2011.

Chen J., Chiu S., Wang Z. and Loo T.Y., Prevention Strategies for Recurrence and Metastasis of Breast Cancer by Chinese Medicine, OOTR. 2011.

Chen J., Chiu S., Chok H. and Wang Z., revention Strategies for Recurrence and Metastasis of Breast Cancer by Chinese Medicine. Global Traditional Chinese Medicine, 2011.

Li L., Wang Z. and Lo K...C., ‘Poisonous drugs’ and ’Sweet drugs’- Analysis of the culture of drug classification in the “Yellow Emperor’s Internal Classic”, The 9th Meeting of The Consortium for Globalization of Chinese Medicine (CGCM). Hong Kong, 2010.

Wang N., Wang Z., Loo T.Y. and Chen J., Ellagic Acid, a phenolic compound, exerts anti-angiogenesis effect through VEGF production and VEGFR-2 signaling pathway, OOTR. 2011.

Wang Z., Loo T.Y., Wang N., Chow Y. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By a Medicinal Herb: Sanguisorba officinalis L, 2011.

Wang Z., Wang D., LOO W., Cheng Y., Chen L., Shen J., Yang D., Chow L., Guan X. and Chen J., LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis , Breast cancer research and treatment . Epub, 2011, 2012: 131: 791-800.

Wang Z., Loo T.Y., Wang N. and Chen J., Proteomic Identification of Anti-cancer Proteins in Dioscin-treated Human Esophogeal Cancer Kyse510 cells, OOTR. 2011.

Wang Z., Wang D., Loo T.Y., Cheng Y., Chen L., Shen J., yang D., Chow L., Guan X. and Chen J., Spatholobus sub erectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint, 2010.

cheng Y., Wang Z., LIu H., Wang D. and Chen J., Total Flavonoids and its Anti-tumor Activities by Different Solvent Extract from Spatholobus sub erectus Dunn, 2011.