DEPT OF PAEDIATRICS & ADOLESCENT MED
| Researcher : Au KY |
| List of Research Outputs |
| Fang J.W., Li C.B., Au K.Y., Yim H.C.H. and Lau A.S.Y., Interleukin-17A differentially modulates BCG induction of cytokine production in human blood macrophages., Journal of Leukocyte Biology. 2011. |
| Li C.B., Au K.Y., Yim H.C.H. and Lau A.S.Y., HIV Tat in AIDS pathogenesis: dysregulation of pro-inflammatory and anti-inflammatory cytokines , ASBMB's Special Symposium "Recent Advances in Pathogenic Human Viruses". 2011. |
| Li C.B., Au K.Y., Fang J.W., Yim H.C.H., Chow K.H., Ho P.L. and Lau A.S.Y., HIV-1 trans-activator protein dysregulates IFN-γ signaling and contributes to the suppression of autophagy induction., AIDS. 2011, 25(1): 15-25. |
| Researcher : Chan GCF |
| Project Title: | Treatment protocol for childhood medulloblastoma in Hong Kong |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/2001 |
| Project Title: | Review of local experience in the management of childhood myelodysplastic syndrome |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/2001 |
| Project Title: | Survey on the prevalence on use of alternative medical treatment in paediatric patients |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 09/2001 |
| Project Title: | Direct generation and functional characterization of human dendritic cells derived from bone marrow cells of leukemic origins |
| Investigator(s): | Chan GCF, Chiu CSW, Ma ESK, Huang F |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/2002 |
| Project Title: | King's/HKU Fellowship Awards 2009-10 |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | King's/HKU Fellowship Awards |
| Start Date: | 09/2009 |
| Project Title: | Suppression on Mesenchymal Stromal Cells Function Can Reduce the Migration & Invasion Potentials of the Neuroblastoma Cells |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2010 |
| Project Title: | The immunomodulatory function of artepillin C (Art-C) in allogeneic mixed leucocytes reaction setting |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Anderson L., Roughton M., Tanner M., Lam W., Au W.Y., Chu W. and Chan G.C.F., Reproducibility of Single Breathhold T2* Magnetic Resonance for Tissue Iron Measurement between Five International Thalassemia Centers, JMRI (in press). 2010. |
| Au W.Y., Lee V., Kho B., Ling A.S., Chan D., Chan E.Y., Chan G.C.F., Cheung W.W., Lau C.W. and Lee C.Y., A synopsis of current haemophilia care in Hong Kong, Hong Kong Med J. 2011 Jun;17(3):189-94. 2011. |
| Burd A. and Chan G.C.F., Classification of vascular anomalies, Hong Kong Medical Journal. 2010, 16(5). |
| Chan B.P., Wong H.L., Wong M.Y., Chan G.C.F. and Yang Z., Methods to Enhance Mesenchymal Stem Cell Migration. , US Regular Patent Application (filed on 14 June 2011) (Application No. 13/159,835). 2011. |
| Chan G.C.F., Shing M.M.K., Yuen H.L., Li R.C.H., Li C.K., Ha S.Y. and Li C.K., Best Research Award (ASPR): The epidemiology of childhood brain tumors in Hong Kong report from the Hong Kong Pediatric Haematology Oncology Study Group., Pediatric Academic Societies and Asian Society for Pediatric Research 2011 Joint Meeting (PAS/ASPR 2011), Denver, Colorado, Apr 30-May 3, 2011.. 2011. |
| Chan G.C.F., Centre for Cancer Research, Radio Television Hong Kong (RTHK), 21 Dec. 精靈一點, 2010. |
| Chan G.C.F., Chairman of lecture ‘Different Dimensions in Thalassaemia Study’, organized by Hong Kong Scoiety for the Study of Thalassaemia, Hong Kong, 26 May. 2011. |
| Chan G.C.F., Clinical Manifestations and Treatments of Childhood Brain Tumors: What We Cannot Learn From the Textbook?, 14th ASEAN Pediatric Congress, Singapore, April 14-17,. 2011. |
| Chan G.C.F., Current clinical status of long acting Factor IX-Fc (B-long)., 4th East Asian Hemophilia Conference. Tianjin, China. June 10-12, . 2011. |
| Chan G.C.F., Current issues in management of invasive pneumococcal disease., Medical Tribune. PXV. 2011. |
| Chan G.C.F., Current issues in management of invasive pneumococcal disease, Industry Update, Medical tribune, P. XV; Mar. 2011. |
| Chan G.C.F., Editorial: The changing of disease patterns in the modern era. , HK J Paediatr (new series) 2011;16:245-6. 2011, 16: 245-246. |
| Chan G.C.F., Enough or not enough, the manpower issue of paediatricians., (Editorial) *Hong Kong Journal of Paediatrics. 2011;16:75-76.. 2011. |
| Chan G.C.F., Extrinsic factors that can affect the behaviour of human mesenchymal stem cells., 2nd International Conference of Research Academy of Health & Medical Science, Pafos, Cyprus, July 8-12, 2010. (Plenary Lecture). 2010. |
| Chan G.C.F., Facts & myths about herbal medicine. , The Bottomline Issues and Controversies in Pediatrics. Co-organized by Dept of Pediatrics & Brokenshire College-Nursing Dept, Brokenshire Memorial Hospital, Davao City, USA, 12-13 March. 2011. |
| Chan G.C.F., Focus on Future Therapies: Stem Cell Treatment for Diseases of Childhood (Plenary Lecture), 48th Annual Convention of the Philippines Pediatric Society, Manila, Philippines. April 3-6. 2011. |
| Chan G.C.F., Haemolytic uraemic syndrome – An emerging problem of invasive pneumococcsal infection? , 11th Symposium of Hong Kong Society for Paediatric Immunology and Infectious Diseases, Hong Kong, 22 June . 2011. |
| Chan G.C.F., Invasive Pneumococcal Infection and Hemolytic Uremic Syndrome., Monthly Meeting of HKMA Taipo Study Group, Taipo. April 12,. 2011. |
| Chan G.C.F., Invasive Pneumococcal Infection and Hemolytic Uremic Syndrome., Paediatric Immunology and Infectious Diseases Course 2011. Hong Kong Society for Paediatric Immunology & Infectious Diseases. June 22,. 2011. |
| Chan G.C.F., Paediatric education and training; Are we ready for a change?, (Editorial) *Hong Kong Journal of Paediatrics. 2011;16:1-2. 2011. |
| Chan G.C.F., The New Stem of Life? Current Use of Stem Cell for Diseases of Childhood (Symposium Lecture), 48th Annual Convention of the Philippines Pediatric Society, Manila, Philippines. April 3-6,. 2011. |
| Chan G.C.F., The Potential & Barriers of Mesenchymal Stem Cells Application in Clinical Medicine., Research Seminar of Department of Medical & Moelcular Genetics, Guy’s Hospital, King’s College London, London, UK, July 6, . 2010. |
| Chan G.C.F., The Role of Mesenchymal Stem Cells in Autoimmune Diseases & Cancers., Monthly Research Symposium of King’s College Hospital at Denmark Hill, July 21, . 2010. |
| Chan G.C.F., Shing M.M.K., Yuen H.L., Li R.C.H., Li C.K., Ha S.Y. and Li C.K., The epidemiology of childhood brain tumors in Hong Kong report from the Hong Kong Pediatric Haematology Oncology Study Group., Pediatric Academic Societies and Asian Society for Pediatric Research 2011 Joint Meeting (PAS/ASPR 2011), Denver, Colorado, Apr 30-May 3, 2011. #Best Research Award (ASPR). 2011. |
| Chan G.C.F., The recent advances in the management of Wilm’s tumor., 1st Guangdong Pediatric Solid Tumor Study Group Meeting, Guangdong Anti-Cancer Society & Researcher Meeting of SYSU 5010 Research Project on Wilm Tumor. Guangdong, China, April 1-2, . 2011. |
| Chan G.C.F., The use of traditional Chinese medicine in children with cancer: insight from the in vitro & in vivo studies. , 5th St Jude-Viva Forum in Pediatric Oncology 2011, Singapore, 21-23 March. 2011. |
| Chan G.C.F., Thrombocytopenia in children: to transfuse or not. The Bottomline Issues and Controversies in Pediatrics., Co-organized by Dept of Pediatrics & Brokenshire College-Nursing Dept, Brokenshire Memorial Hospital, Davao City, USA, 12-13 March. 2011. |
| Chan G.C.F., 兒童腦腫瘤非不治之症, 都市日報叢書系列-“都市健康小百科第2冊”,香港大學李嘉誠醫學院, Hong Kong, April 2011;p18-19. 2011. |
| Chan S., Ngan E.S.W., Man N.K., Tam P.K.H. and Chan G.C.F., Established an orthotopic neuroblastoma model for the study of neuroblastoma progression, 4th National Pediatric Surgical Oncology Conference & 4th Cross Strait Symposium on Pediatric Oncology, Hong Kong, 5-6 November . 2010. |
| Chen M., Chan G.C.F. and Cheung Y.F., Iron overload induces mitochondria-dependent apoptosis and titin degradation in cardiomyocytes. , 15th Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, Dec 1 & 2. 2010. |
| Cheuk D.K.L., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Ewing sarcoma family of tumors in children: experience of Queen Mary Hospital., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Outcomes of osteosarcoma in children: Experience of Queen Mary Hospital., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Chan G.C.F. and Ha S.Y., Outcomes of pediatric chronic myeloid leukemia: Experience of Queen Mary Hospital., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Lee T.L., Chan G.C.F. and Ha S.Y., Vaccines for prophylaxis of viral infections in patients with hematological malignancies., Cochrane Database Syst Rev 3: CD006505. 2011. |
| Cheung Y.F., Li S.N., Chan G.C.F., Wong S.J. and Ha S.Y., Left Ventricular Twisting and Untwisting Motion in Childhood Cancer Survivors, Echocardiography. 2011 May 25. doi: 10.1111/j.1540-8175.2011.01429.x. . 2011. |
| Cheung Y.F., Hong W., Chan G.C.F., Wong S.J. and Ha S.Y., Left ventricular myocaridal deformation and mechanical dyssynchrony in children with normal ventricular shortening fraction after anthracycline therapy, Heart. 2010, 96: 1137-1141. |
| Cheung Y.F., Liang X., Chan G.C.F., Wong S.J. and Ha S.Y., Myocardial iron load in patients with beta-thalassaemia major is associated with global left ventricular mechanical dyssynchrony (Abstract: Circulation 2010;122:A12192), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Chow W.C., Ha S.Y. and Chan G.C.F., Vincristine can induce regression of vascular malformation in long standing refractory Kasabach Merritt Phenomenon. , HK J Paediatr (new series). 2011, 16: 121-1224. |
| Chow W.C., Ha S.Y. and Chan G.C.F., Vincristine can induce regression of vascular malformation in long standing refractory Kasabach Merritt Phenomenon. , Hong Kong Journal of Paediatrics. 2011;16:121-124.. 2011. |
| Ha S.Y., Mok S.P., Lau Y.S., Rasalkar D.D., Cheuk D.K.L., Chiang A.K.S., Ho M.H.K. and Chan G.C.F., Intermediate term evaluation of a practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*, Hemoglobin 35(3):199-205. 2011. |
| Li J., Law H.K.W., Lau Y.L. and Chan G.C.F., Effect of Cisplatin, Hydroxyurea, Topotecan and Daunorubicin on Human Mesenchymal Stem Cells, Journal of Experimental Hematology. 2010, 18(4): 991-996. |
| Liu J.Q., Lee T.F., Miedzyblocki M. and Chan G.C.F., Effects of Sodium Tanshinone IIA Sulfonate on platelet aggregation in healthy newborn piglets., J Ethnopharma 2011, Mar 29 (Epub). 2011. |
| Ma M., Ye J.Y., Deng R.X., Dee C.M. and Chan G.C.F., Mesenchymal stem cells enhanced metastasis of neuroblastoma via SDF-1/CX CR4 and SDF-1/CXCR7 signalling., 15th Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, Dec 1 & 2. 2010. |
| So C.C., Leung Y.Y., Yip S.F., Chan S.Y., Lam C.C., Chan G.C.F., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus pneumoniae infection in five Chinese paediatric patients, Hong Kong Med J. 2011 Jun;17(3):237-41. 2011. |
| So J.C.C., Leung R.Y.Y., Yip S.F., Chan S.Y., Lam C.C.K., Chan G.C.F., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus pneumoniae infection in five Chinese paediatric patients, Hong Kong Med J. 2011, 17(3): 237-41. |
| Ting J.Y., Chan S.Y., Lung D.C., Ho A.C.C., Chiang A.K.S., Ha S.Y., Tsoi N.S. and Chan G.C.F., Intra-abdominal Rhizopus microsporus Infection Successfully Treated by Combined Aggressive Surgical, Antifungal, and Iron Chelating Therapy, Journal of Pediatric Hematology Oncology. 2010, 32(6): e238-e240. |
| Tsang M.L., Cheung C.Y., Cheung S.L.C., Kung A.Y.H., Kwok M.N., Tang K.T., Wong S.W., Yuen W.S.V., Wong H.M., Chan G.C.F. and Chu C.H., Oral mucosal status of children and adolescent undergoing cancer therapy in Hong Kong, The 2nd Hong Kong International Dental Expo And Symposium. 2011. |
| Wong M.Y., Wong H.L., Diao H., Chan G.C.F., Yang Z. and Chan B.P., Regulation of migration characteristics of human mesenchynal stem cells (hMSCs) by encapsulation in collagen matrix. , International Society of Stem Cell Research (ISSCR) 9th Annual Meeting, June 15 - 18, 2011, Toronto, Ontario Canada. . 2011, 147. |
| Xiong H., Zeng L.K., Ha S.Y., Chiang A.K.S., Cheuk D.K.L. and Chan G.C.F., A small cohort review of neonatal transient myeloproliferative disease in Chinese children. , HK J Paediatr (new series) 2011;16:258-63. 2011, 16: 258-263. |
| Xiong H., Ha S.Y., Chiang A.K.S., Cheuk D.K.L., Zeng L.K. and Chan G.C.F., A small cohort review of neonatal transient myeloproliferative disease in Chinese children, Hong Kong Journal of Paediatrics (new series). 2011, 16: 258-263. |
| Xiong H., Ha S.Y., Chiang A.K.S., Lau Y.L., Chan G.C.F. and Hu Q., Reversible leukoencephalopathy following intrathecal methotrexate. , HK J Paediatr (new series). 2010, 15: 327-331. |
| Ye J.Y., Chan G.C.F. and Yang M., Serotonin enhances megakaryopoiesis and proplatelet formation and stimulates TPO released from mesenchymal stromal cells (oral presentation)., 15th Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, Dec 1 & 2, 2010. |
| Yu J.L., Chung S.K. and Chan G.C.F., Epac regulates human mesenchymal stem cells homing., 15th Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, Dec 1 & 2, 2010 . 2010. |
| Zhang Z.Q., Chan G.C.F., Lam C.C.K., So J.C.C., Cheuk D.K.L., Chiang A.K.S. and Ha S.Y., The clinical features of Chinese children with von Willebrand disease: the experience of a tertiary institute., HK J Paediatr: 16:95-100, 2011. 2011. |
| Researcher : Chan KW |
| List of Research Outputs |
| Lai C.T.M., Chan K.W., Wong S.J., Chow P.C. and Cheung Y.F., Circulating levels of biomarkers of collagen synthesis correlate with left ventricular mechanical dyssynchrony in adolescents after repair of tetralogy of fallot (Abstract: Circulation 2010; 122:A12164), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Lee P.P.W., Chan K.W., Chen T.X., Jiang L.P., Wang X.C., Zeng H.S., Chen X.Y., Liew W.K., Chen J., Chu K.M., Chan L.L., Shek L., Lee A.C.W., Yu H.H., Li Q., Xu C.G., Sultan-Ugdoracion G., Latiff Z.A., Latiff A.H.A., Jirapongsananuruk O., Ho M.H.K., Lee T.L., Yang X.Q. and Lau Y.L., Molecular diagnosis of severe combined immunodeficiency-identification of IL2RG, JAK3, IL7R, DCLRE1C, RAG1, and RAG2 mutations in a cohort of Chinese and southeast Asian Children, Journal of Clinical Immunology. 2011, 31: 281-296. |
| Tao K.P., Fong S.W., Lu Z., Ching Y.P., Chan K.W. and Chan S.Y., TSPYL2 is important for G1 checkpoint maintenance upon DNA damage, PLoS One. 2011, 6(6): e21602. |
| Researcher : Chan KW |
| List of Research Outputs |
| Lai C.T.M., Chan K.W., Wong S.J., Chow P.C. and Cheung Y.F., Circulating levels of biomarkers of collagen synthesis correlate with left ventricular mechanical dyssynchrony in adolescents after repair of tetralogy of fallot (Abstract: Circulation 2010; 122:A12164), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Lee P.P.W., Chan K.W., Chen T.X., Jiang L.P., Wang X.C., Zeng H.S., Chen X.Y., Liew W.K., Chen J., Chu K.M., Chan L.L., Shek L., Lee A.C.W., Yu H.H., Li Q., Xu C.G., Sultan-Ugdoracion G., Latiff Z.A., Latiff A.H.A., Jirapongsananuruk O., Ho M.H.K., Lee T.L., Yang X.Q. and Lau Y.L., Molecular diagnosis of severe combined immunodeficiency-identification of IL2RG, JAK3, IL7R, DCLRE1C, RAG1, and RAG2 mutations in a cohort of Chinese and southeast Asian Children, Journal of Clinical Immunology. 2011, 31: 281-296. |
| Tao K.P., Fong S.W., Lu Z., Ching Y.P., Chan K.W. and Chan S.Y., TSPYL2 is important for G1 checkpoint maintenance upon DNA damage, PLoS One. 2011, 6(6): e21602. |
| Researcher : Chan KY |
| List of Research Outputs |
| Yeung W.L., Wong V.C.N., Chan K.Y., Hui J., Fung C.W., Yau F.T., Ko C.H., Lam C.W., Mak C.M., Siu S. and Low L.C.K., Expanding Phenotype and Clinical Analysis of Tyrosine Hydroxylase Deficiency, J Child Neurol 2011 26(2): 179-187. 2011. |
| Researcher : Chan LLY |
| List of Research Outputs |
| Chan L.L.Y., Cheung B.K.W., Li C.B. and Lau A.S.Y., Mycobacterial evasion of immunity: Induction of IL-10 and STAT3 in the downregulation of IFN-gamma-induced MHC class II molecule expression, 15th Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, 1-2 Dec. 2010. |
| Researcher : Chan LY |
| List of Research Outputs |
| Chiu S.S.S., Chan K.H., Wong W.H.S., Chan L.Y. and Peiris J.S.M., Age-matched comparison of children hospitalized for 2009 pandemic H1N1 influenza with those hospitalized for seasonal H1N1 and H3N2, PLoS ONE. 2011, 6 (7): e21837. |
| Researcher : Chan PL |
| List of Research Outputs |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Researcher : Chan S |
| List of Research Outputs |
| Chan S., Ngan E.S.W., Man N.K., Tam P.K.H. and Chan G.C.F., Established an orthotopic neuroblastoma model for the study of neuroblastoma progression, 4th National Pediatric Surgical Oncology Conference & 4th Cross Strait Symposium on Pediatric Oncology, Hong Kong, 5-6 November . 2010. |
| Researcher : Chan SHS |
| List of Research Outputs |
| Chan S.H.S., Wong V.C.N., Fung C.W., Dale R.C. and Vincent A., Anti-NMDA Receptor Encephalitis With Atypical Brain Changes on MRI, Pediatric Neurology. 2010, 43(4): 274-278. |
| Researcher : Chan SY |
| Project Title: | Phenotype analysis of Tspyl2/Nap79 knockout mice |
| Investigator(s): | Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2009 |
| Completion Date: | 03/2011 |
| Project Title: | The effect of Tspyl2, a Novel Nucleosome Assembly Protein, on gene expression profile in the hippocampus |
| Investigator(s): | Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2009 |
| Completion Date: | 12/2011 |
| Project Title: | Role of the nucleosome assembly protein TSPY-like 2 in cell cycle control upon DNA damage |
| Investigator(s): | Chan SY, Ching YP |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| Project Title: | 44th Annual Meeting of JSDB TSPYL2 Is Important for G1 Checkpoint Maintenance upon DNA Damage |
| Investigator(s): | Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Chung B.H.Y., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Chau A.K.T. and Lau Y.L., Two Chinese patients with Loeys-Dietz Syndrome due to TGFBR2 mutations, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Liang X., Chiu P.H., Yip K.Y. and Chan S.Y., Subcellular localization of SUN2 regulated by lamin A and rab5, PLoS One. 2011, 6(5): e20507. |
| So C.C., Leung Y.Y., Yip S.F., Chan S.Y., Lam B.C.C., Chan G.C., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus, pneumoniae infection in five Chinese paediatric patients, Hong Kong Medical Journal [PMID 21636872, PubMed in process]. 2011, 17(3): 237-241. |
| So J.C.C., Leung R.Y.Y., Yip S.F., Chan S.Y., Lam C.C.K., Chan G.C.F., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus pneumoniae infection in five Chinese paediatric patients, Hong Kong Med J. 2011, 17(3): 237-41. |
| Tao K.P., Ching Y.P. and Chan S.Y., TSPYL2 Is Important for G1 Checkpoint Maintenance upon DNA Damage, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2007. |
| Tao K.P., Fong S.W., Lu Z., Ching Y.P., Chan K.W. and Chan S.Y., TSPYL2 is important for G1 checkpoint maintenance upon DNA damage, PLoS One. 2011, 6(6): e21602. |
| Ting J.Y., Chan S.Y., Lung D.C., Ho A.C.C., Chiang A.K.S., Ha S.Y., Tsoi N.S. and Chan G.C.F., Intra-abdominal Rhizopus microsporus Infection Successfully Treated by Combined Aggressive Surgical, Antifungal, and Iron Chelating Therapy, Journal of Pediatric Hematology Oncology. 2010, 32(6): e238-e240. |
| Tsang K.H., Tao K.P., Lai S.K., Chan Y.S. and Chan S.Y., Tspy12 regulates hippocampal long-term potentiation via NMDA receptor subunits NR2A and NR2B expression, Abstracts of 43rd Annual Meeting for the Japanese Society of Developmental Biologists: 286. [Kyoto. June 20-23, 2010]. 2010. |
| Wong K.K., Li Q., Wong H.T., Tsang K.H., Lai S.K., McAlonan G.M., Chan Y.S. and Chan S.Y., TSPYL2 regulates CREB-Dependent Gene Expression, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2079. |
| Wong K.K., Li Q., McAlonan G.M. and Chan S.Y., The role of TSPYL2 in learning and memory, 15th Research Postgraduate Symposium 2010 (December 1-2, 2010). 2010. |
| Researcher : Chan SY |
| List of Research Outputs |
| Chung B.H.Y., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Chau A.K.T. and Lau Y.L., Two Chinese patients with Loeys-Dietz Syndrome due to TGFBR2 mutations, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Liang X., Chiu P.H., Yip K.Y. and Chan S.Y., Subcellular localization of SUN2 regulated by lamin A and rab5, PLoS One. 2011, 6(5): e20507. |
| So C.C., Leung Y.Y., Yip S.F., Chan S.Y., Lam B.C.C., Chan G.C., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus, pneumoniae infection in five Chinese paediatric patients, Hong Kong Medical Journal [PMID 21636872, PubMed in process]. 2011, 17(3): 237-241. |
| So J.C.C., Leung R.Y.Y., Yip S.F., Chan S.Y., Lam C.C.K., Chan G.C.F., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus pneumoniae infection in five Chinese paediatric patients, Hong Kong Med J. 2011, 17(3): 237-41. |
| Tao K.P., Ching Y.P. and Chan S.Y., TSPYL2 Is Important for G1 Checkpoint Maintenance upon DNA Damage, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2007. |
| Tao K.P., Fong S.W., Lu Z., Ching Y.P., Chan K.W. and Chan S.Y., TSPYL2 is important for G1 checkpoint maintenance upon DNA damage, PLoS One. 2011, 6(6): e21602. |
| Ting J.Y., Chan S.Y., Lung D.C., Ho A.C.C., Chiang A.K.S., Ha S.Y., Tsoi N.S. and Chan G.C.F., Intra-abdominal Rhizopus microsporus Infection Successfully Treated by Combined Aggressive Surgical, Antifungal, and Iron Chelating Therapy, Journal of Pediatric Hematology Oncology. 2010, 32(6): e238-e240. |
| Tsang K.H., Tao K.P., Lai S.K., Chan Y.S. and Chan S.Y., Tspy12 regulates hippocampal long-term potentiation via NMDA receptor subunits NR2A and NR2B expression, Abstracts of 43rd Annual Meeting for the Japanese Society of Developmental Biologists: 286. [Kyoto. June 20-23, 2010]. 2010. |
| Wong K.K., Li Q., Wong H.T., Tsang K.H., Lai S.K., McAlonan G.M., Chan Y.S. and Chan S.Y., TSPYL2 regulates CREB-Dependent Gene Expression, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2079. |
| Wong K.K., Li Q., McAlonan G.M. and Chan S.Y., The role of TSPYL2 in learning and memory, 15th Research Postgraduate Symposium 2010 (December 1-2, 2010). 2010. |
| Researcher : Chau AKT |
| List of Research Outputs |
| Chung B.H.Y., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Chau A.K.T. and Lau Y.L., Two Chinese patients with Loeys-Dietz Syndrome due to TGFBR2 mutations, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Researcher : Chen W |
| List of Research Outputs |
| Wong V.C.N., Chen W. and Liu W.L., Randomized Controlled Trial of Electro-Acupuncture for Autism Spectrum Disorder, Alternative Medicine Review. 2010, 15(2): 136-146. |
| Researcher : Cheuk DKL |
| List of Research Outputs |
| Cheuk D.K.L., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Ewing sarcoma family of tumors in children: experience of Queen Mary Hospital., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Outcomes of osteosarcoma in children: Experience of Queen Mary Hospital., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Chan G.C.F. and Ha S.Y., Outcomes of pediatric chronic myeloid leukemia: Experience of Queen Mary Hospital., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Lee T.L., Chan G.C.F. and Ha S.Y., Vaccines for prophylaxis of viral infections in patients with hematological malignancies., Cochrane Database Syst Rev 3: CD006505. 2011. |
| Ha S.Y., Mok S.P., Lau Y.S., Rasalkar D.D., Cheuk D.K.L., Chiang A.K.S., Ho M.H.K. and Chan G.C.F., Intermediate term evaluation of a practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*, Hemoglobin 35(3):199-205. 2011. |
| Wong V.C.N., Cheuk D.K.L., Lee S. and Chu V.L.Y., Acupuncture for acute management and rehabilitation of traumatic brain injury. , Cochrane Database of Systematic Reviews 2011, Issue 5. Art. No.: CD007700. DOI: 10.1002/14651858.CD007700.pub2. . 2011. |
| Xiong H., Zeng L.K., Ha S.Y., Chiang A.K.S., Cheuk D.K.L. and Chan G.C.F., A small cohort review of neonatal transient myeloproliferative disease in Chinese children. , HK J Paediatr (new series) 2011;16:258-63. 2011, 16: 258-263. |
| Xiong H., Ha S.Y., Chiang A.K.S., Cheuk D.K.L., Zeng L.K. and Chan G.C.F., A small cohort review of neonatal transient myeloproliferative disease in Chinese children, Hong Kong Journal of Paediatrics (new series). 2011, 16: 258-263. |
| Zhang Z.Q., Chan G.C.F., Lam C.C.K., So J.C.C., Cheuk D.K.L., Chiang A.K.S. and Ha S.Y., The clinical features of Chinese children with von Willebrand disease: the experience of a tertiary institute., HK J Paediatr: 16:95-100, 2011. 2011. |
| Researcher : Cheung PT |
| Project Title: | The Endocrine Society 83rd Annual Meeting Mutations of the CYP11B2 Gene in a Patient with Corticosterone Methyl Oxidase Type II Deficiency |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 06/2001 |
| Project Title: | International Perinatal Collegium 2005 Meeting New Approaches in Old Models - Identification of Novel Molecular Alterations in Neonatal Mouse Hypoxic-Ischaemic Brain Damage |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 07/2005 |
| Project Title: | 4th Asian Epigenomics Meeting Methyl mercury induced epigenetic dysregulation of BDNF gene in NG108 cells in vitro – a possible mechanism of environment-epigenome interactions underlying neuropsychiatric and neurodevelopmental disorders. |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 08/2009 |
| List of Research Outputs |
| Lo A.C.Y., Wong C.H., Nian S., Cheung P.T., Chan B.P. and Wong D.S.H., A cell-based drug delivery system using collagen-alginate composite matrix: in vitro and in vivo studies, 2011 Congress of the Asia-Pacific Academy of Ophthalmology. 2011. |
| Researcher : Cheung YF |
| Project Title: | CSX/NKX2.5 mutations in patients with pulmonary atresia and intact ventricular septum |
| Investigator(s): | Cheung YF, Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Project Title: | Development of a multimedia tool for teaching of paediatric cardiology |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants |
| Start Date: | 04/2004 |
| Project Title: | Circulating Endothelial and Endothelial Progenitor Cells, Arterial Function, and Ventriculo-Arterial Interaction in Patients with Beta-Thalassaemia Major |
| Investigator(s): | Cheung YF, Ha SY, Chan GCF, Yang M |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2008 |
| Completion Date: | 08/2010 |
| Project Title: | Impact of right ventricular volume overload on left ventricular strain and torsion in patients after surgical repair of tetralogy of Fallot: analysis by novel 3-dimensional speckle tracking echocardiography |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2009 |
| Project Title: | Right and Left Ventricular Mechanical Dyssynchrony in Iron Loaded Patients with Beta-Thalassaemia Major |
| Investigator(s): | Cheung YF, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2010 |
| Project Title: | Mechanics of Ventricular-Ventricular Interaction in Patients After Tetralogy of Fallot Repair: Analysis by Three-dimensional Speckle Tracking Echocardiography |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2011 |
| Project Title: | Circulating MicroRNA and Right Ventricular Function in Patients After Repair of Tetralogy of Fallot |
| Investigator(s): | Cheung YF, Ng EKO |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| List of Research Outputs |
| Chen M., Chan G.C.F. and Cheung Y.F., Iron overload induces mitochondria-dependent apoptosis and titin degradation in cardiomyocytes. , 15th Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, Dec 1 & 2. 2010. |
| Cheung E.W.Y., Wong W.H.S. and Cheung Y.F., Meta-Analysis of Pulmonary Valve Replacement After Operative Repair of Tetralogy of Fallot, American Journal of Cardiology. 2010, 106: 552-557. |
| Cheung Y.F., Advances in echocardiographic evaluation of heart function in congenital heart disease, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, PR China, Sept 20 - 22 . 2010. |
| Cheung Y.F., Associate Editor , Hong Kong Journal of Pediatrics. 2011. |
| Cheung Y.F., Atypical Kawasaki Disease, Hong Kong College of Paediatricians, Paediatric Grandrounds: Challenging Clinical Cases, Hong Kong , 2010. |
| Cheung Y.F., Cardiovascular health in thalassaemia major patients, The 3rd International Conference on Thalassemia in China & The 2nd Asia Pacific Iron Academy Conference. 2010. |
| Cheung Y.F., Chairperson: Oral Presentation on Brugada Syndrome; i) Reproducibility of the signal-averaged ECG in a family screened for Brugada Syndrome; ii) Cardiac event rate in Brugada patients; iii) Value of C-reactive protein in patients with asymptomatic and symptomatic Brugada syndrome; and iv) A 10-year single-centre prospective study on asymtomatic patients with spontaneous Cove type (Type I) Brugada ECG pattern, CardioRhythm, Hong Kong, 25th February 2011 , 2011. |
| Cheung Y.F., Clinical research ethics: righrts of the human research subjects, 5th case-based workshop on research integrity, LKS Faculty of Medicine, The University of Hong Kong . 2011. |
| Cheung Y.F., Functional results in anatomic correction of corrected TGA, the 7th International Congress of Update in Cardiology and Cardiovascular Surgery, Antalya, Turkey, March 24 - 27 2011 . 2011. |
| Cheung Y.F., How to Conduct and Publish Clinical Research , Nursing Research Seminar, Hong Kong, 18 August 2010. 2010. |
| Cheung Y.F., How to evaluate RV in repaired TOF long after repair by Echo, the 7th International Congress of Update in Cardiology and Cardiovascular Surgery, Antalya, Turkey, March 24 - 27, 2011. 2011. |
| Cheung Y.F., Identification of paedatric patients with increased cardiovascular risk, Centro Hospitalar Conde Sao Januario, Macau, 2011. 2011. |
| Cheung Y.F., Imaging Moderator of Poster session, the 3rd Congress of Asia-Pacific Pediatric Cardiac Society, Chiba, Japan, 6 - 8 July 2010 , 2010. |
| Cheung Y.F., Li S.N., Chan G.C.F., Wong S.J. and Ha S.Y., Left Ventricular Twisting and Untwisting Motion in Childhood Cancer Survivors, Echocardiography. 2011 May 25. doi: 10.1111/j.1540-8175.2011.01429.x. . 2011. |
| Cheung Y.F., Hong W., Chan G.C.F., Wong S.J. and Ha S.Y., Left ventricular myocaridal deformation and mechanical dyssynchrony in children with normal ventricular shortening fraction after anthracycline therapy, Heart. 2010, 96: 1137-1141. |
| Cheung Y.F., Long-term vascular health in Kawasaki Disease, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, PR China, Sept 20 - 22. 2010. |
| Cheung Y.F., Moderator of Recent development of Imaging, the 3rd Congress of Asia-Pacific Pediatric Cardiac Society, Chiba, Japan, 6 - 8 July 2010, 2010. |
| Cheung Y.F., Liang X., Chan G.C.F., Wong S.J. and Ha S.Y., Myocardial iron load in patients with beta-thalassaemia major is associated with global left ventricular mechanical dyssynchrony (Abstract: Circulation 2010;122:A12192), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Cheung Y.F., Practical evaluation of cardiac failure by echocardiography, The 3rd Congress of Asia-Pacific Society of Pediatric Cardiology and Cardiac Surgery, Tokyo, Japan, 6 - 8 July 2010. |
| Cheung Y.F., Role of echocardiography in the diagnosis and follow-up after repair of conotruncal defects, the Symposium on Pediatric Cardiovascular Medicine in the 21st Century, Children’s Hospital of Fudan University, Shanghai, China, Sept 16 - 18. 2010. |
| Cheung Y.F., Second Editorial Board of Chinese Journal of Evidence-based Pediatrics, 2010. |
| Cheung Y.F., Three-Dimensional Wall Motion Tracking: A New Tool for Assessment for Ventricular Dyssynchrony, 5th Congress of Asian Society of Cardiovascular Imaging (Industry Sponsor Symposium), Hong Kong, 17-19 June 2011. |
| Cheung Y.F., Updates on medical management of paediatric cardiovascular disease, Centro Hospitalar Conde Sao Januario, Macau 2011. 2011. |
| Cheung Y.F., Ventricular Mechanics in Congenital Heart Disease, 19th Annual Scientific Congress, Hong Kong College of Cardiology, 29 April to 1 May 2011. 2011. |
| Cheung Y.F., Young Investigator Award (supervisor of Dr Carline Koh): Impact of right ventricular pacing on left ventricular torsion in children with congenital heart block , The 3rd Congress of Asia-Pacific Society of Pediatric Cardiology and Cardiac Surgery, Tokyo, Japan. 2010. |
| Koh C., Hong W., Wong S.J. and Cheung Y.F., Systolic-diastolic coupling of myocardial deformation of the left ventricle in children with left ventricular noncompaction, Heart Vessels. 2010, 25: 493-499. |
| Lai C.T.M., Chan K.W., Wong S.J., Chow P.C. and Cheung Y.F., Circulating levels of biomarkers of collagen synthesis correlate with left ventricular mechanical dyssynchrony in adolescents after repair of tetralogy of fallot (Abstract: Circulation 2010; 122:A12164), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Li S., Wong S.J. and Cheung Y.F., Left ventricular eccentricity impairs three-dimensional systolic radial strain and torsion in patients after repair of tetralogy of fallot: a three-dimensional speckle tracking analysis (Abstract: Circulation 2010; 122:A10455), American Heart Association Scientific Sessions 2010, Chicago, 13-17 November 2010. |
| Researcher : Chiang AKS |
| Project Title: | Genetic studies of tubercubosis |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 03/2002 |
| Project Title: | Prospective study of virologic and immunologic parameters of primary Epstein-Barr virus infection in Chinese children |
| Investigator(s): | Chiang AKS, Chan KH |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2003 |
| Project Title: | Prospective study of Epstein-Barr virus (EBV) strains in primary EBV infection |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Project Title: | Longitudinal study of Epstein-Barr virus specific antibody responses in childhood infectious mononucleosis |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2005 |
| Project Title: | Longitudinal study of phenotypic changes and functionality of Epstein-Barr virus (EBV)-specific CD8+ T cell responses in symptomatic and asymptomatic EBV infection |
| Investigator(s): | Chiang AKS, Chan KH |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2007 |
| Completion Date: | 04/2011 |
| Project Title: | Sequence analysis of Epstein-Barr virus strains in nasopharyngeal carcinoma |
| Investigator(s): | Chiang AKS, Kwong DLW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2008 |
| Project Title: | Tracking CD4 and CD8 positive virus-specific polyfunctional T cells in Epstein-Barr virus infection |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2009 |
| Project Title: | Investigation of bortezomib in activation of Epstein-Barr virus (EBV) in EBV-associated malignancies |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| List of Research Outputs |
| 45. Gregorovic G., Bosshard R., Karlstegl C.E., White R.E., Pattle S., Chiang A.K.S., Dittrich-Breiholz O., Kracht M., Russ R. and Farrell P.J., Cellular gene expression that correlates with EBER expression in Epstein-Barr virus-infected lymphoblastoid cell lines, J Virol 85: 3535-3545. 2011. |
| Cheuk D.K.L., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Ewing sarcoma family of tumors in children: experience of Queen Mary Hospital., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Outcomes of osteosarcoma in children: Experience of Queen Mary Hospital., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Chan G.C.F. and Ha S.Y., Outcomes of pediatric chronic myeloid leukemia: Experience of Queen Mary Hospital., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Lee T.L., Chan G.C.F. and Ha S.Y., Vaccines for prophylaxis of viral infections in patients with hematological malignancies., Cochrane Database Syst Rev 3: CD006505. 2011. |
| Chiang A.K.S., Analysis of antigen-specific T cell response in primary Epstein-Barr virus infection., Research Centre of Infection and Immunology Seminars, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, October 11, 2010. 2010. |
| Chiang A.K.S., Diagnosis and treatment of paediatric non-Hodgkin lymphomas., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Chiang A.K.S., Epstein-Barr virus related lymphoproliferative disease, Annual Scientific Meeting 2011, Hong Kong Paediatric Haematology & Oncology Study Group, Hong Kong, 26 March. 2011. |
| Chiang A.K.S., Target therapy in paediatric oncology (治療兒童癌症的新趨勢), 治療兒童癌症的新趨勢, Children Cancer Fund, Jan. 2011. |
| Chiang A.K.S., Target therapy in paediatric oncology., CCF 21st Anniversary & Volunteers Day 2010 Tea Party, Hong Kong, November 27, 2010. 2010. |
| Chiang A.K.S., Use of clofarabine in the treatment of refactory/relapsed pediatric leukaemia – Hong Kong experience, A New Paradigm in the Management of Pediatric Leukaemias, Hong Kong Paediatric Haematology & Oncology Study Group (Sponsored by Genzyme Company), Hong Kong, 17 March. 2011. |
| Ha S.Y., Mok S.P., Lau Y.S., Rasalkar D.D., Cheuk D.K.L., Chiang A.K.S., Ho M.H.K. and Chan G.C.F., Intermediate term evaluation of a practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*, Hemoglobin 35(3):199-205. 2011. |
| Ho D.N.Y., Hui K.F. and Chiang A.K.S., Kinetics of Epstein-Barr virus (EBV) latent and lytic protein expression in EBV-positive Burkitt, epithelial and lymphoblastoid cells upon induction of lytic cycle, The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases. 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and mediates enhanced apoptosis through activation of caspase-dependent pathway., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and medicates enhanced apoptosis through activation of caspase-dependent pathway., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010 (oral presentation). 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid mediates enhanced apoptosis in nasopharyngeal carcinoma through induction of Epstein-Barr virus lytic cycle and activation of caspase-3., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Kwok H. and Chiang A.K.S., Comparative analysis of Epstein-Barr virus (EBV) latent gene and microrna sequences among AKATA, B95.8, AG876 and GD1 EBV genomes., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Kwok H. and Chiang A.K.S., Comparison of Epstein-Barr virus (EBV) latent and microRNA gene sequences of Akata EBV genome to those of prototype EBV genomes., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010. |
| Ning J., Xu X. and Chiang A.K.S., Analysis of CD4+ and CD8+ Epstein-Barr virus-specific polyfunctional T cell responses in Chinese long term carriers by a novel 9-colour flow cytometric assay., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Ning J., Xu X. and Chiang A.K.S., Characterization of CD4+ and CD8+ polyfunctional T cell responses to Epstein-Barr virus (EBV) latent and lytic proteins in Chinese long term carriers., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010. |
| Ning J., Xu X., Chan K.H. and Chiang A.K.S., Long-term carriers generate Epstein–Barr virus (EBV)-specific CD4+ and CD8+ polyfunctional T-cell responses which show immunodominance hierarchies of EBV proteins, Immunology. 2011, 134: 161-171. |
| Ting J.Y., Chan S.Y., Lung D.C., Ho A.C.C., Chiang A.K.S., Ha S.Y., Tsoi N.S. and Chan G.C.F., Intra-abdominal Rhizopus microsporus Infection Successfully Treated by Combined Aggressive Surgical, Antifungal, and Iron Chelating Therapy, Journal of Pediatric Hematology Oncology. 2010, 32(6): e238-e240. |
| Xiong H., Zeng L.K., Ha S.Y., Chiang A.K.S., Cheuk D.K.L. and Chan G.C.F., A small cohort review of neonatal transient myeloproliferative disease in Chinese children. , HK J Paediatr (new series) 2011;16:258-63. 2011, 16: 258-263. |
| Xiong H., Ha S.Y., Chiang A.K.S., Cheuk D.K.L., Zeng L.K. and Chan G.C.F., A small cohort review of neonatal transient myeloproliferative disease in Chinese children, Hong Kong Journal of Paediatrics (new series). 2011, 16: 258-263. |
| Xiong H., Ha S.Y., Chiang A.K.S., Lau Y.L., Chan G.C.F. and Hu Q., Reversible leukoencephalopathy following intrathecal methotrexate. , HK J Paediatr (new series). 2010, 15: 327-331. |
| Zhang Z.Q., Chan G.C.F., Lam C.C.K., So J.C.C., Cheuk D.K.L., Chiang A.K.S. and Ha S.Y., The clinical features of Chinese children with von Willebrand disease: the experience of a tertiary institute., HK J Paediatr: 16:95-100, 2011. 2011. |
| Researcher : Chim S |
| List of Research Outputs |
| So C.C., Leung Y.Y., Yip S.F., Chan S.Y., Lam C.C., Chan G.C.F., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus pneumoniae infection in five Chinese paediatric patients, Hong Kong Med J. 2011 Jun;17(3):237-41. 2011. |
| So C.C., Leung Y.Y., Yip S.F., Chan S.Y., Lam B.C.C., Chan G.C., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus, pneumoniae infection in five Chinese paediatric patients, Hong Kong Medical Journal [PMID 21636872, PubMed in process]. 2011, 17(3): 237-241. |
| So J.C.C., Leung R.Y.Y., Yip S.F., Chan S.Y., Lam C.C.K., Chan G.C.F., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus pneumoniae infection in five Chinese paediatric patients, Hong Kong Med J. 2011, 17(3): 237-41. |
| Ting J.Y., Chan K.L., Wong M.S.C., Chim S. and Wong K.Y., Gastric Pneumatosis in a Premature Neonate, Americal Journal of Perinatol Respiratory. 2011, 1: 11-14. |
| Wong S.N., Tse K.C., Lee K.P., Yuen S.F., Leung L.C., Pau B.C., Chan W.K., Lee K.W., Cheung H.M., Chim S. and Yip C.M., Evaluating different imaging strategies in children after first febrile urinary tract infection, Pediatric Nephrology. 2010, 25(10): 2083-2091. |
| Researcher : Chiu IWS |
| List of Research Outputs |
| Ip P., Chow C.B., Lee S.L., Tsang A.M.C., Chiu I.W.S., Wong W.H.S. and Lau Y.L., The need of policies and legislative changes for tobacco control in Hong Kong - Letter of recommendations to Hong Kong Legislative Council, LC paper No. No. CB(1)1768/10-11(07), Legislative Council, Hong Kong, 2 April 2011. , 2011. |
| Researcher : Chiu SSS |
| Project Title: | Streptococcus pneumoniae carriage in young children in Hong Kong |
| Investigator(s): | Chiu SSS, Ho PL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health Services Research Fund - Full Grants |
| Start Date: | 10/1999 |
| Project Title: | Impact of universal vaccination with the 7-valent conjugate pneumocccal vaccine (PCV7) in Hong Kong on the incidence of pneumonia hospitalization and carriage in children |
| Investigator(s): | Chiu SSS, Ho PL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Centre for Health Protection |
| Start Date: | 07/2010 |
| List of Research Outputs |
| Chiu S.S.S., Chan K.H., Wong W.H.S., Chan L.Y. and Peiris J.S.M., Age-matched comparison of children hospitalized for 2009 pandemic H1N1 influenza with those hospitalized for seasonal H1N1 and H3N2, PLoS ONE. 2011, 6 (7): e21837. |
| Chiu S.S.S., Management of Children with HIV Infection , Post-registration Certificate Course in Child and Adolescent Nursing, Hong Kong. 2010. |
| Chiu S.S.S., Paediatrics and Neonatal Infection, 18th Infection Control Course for Health Care Professionals 2011, Hong Kong. 2011. |
| Chiu S.S.S., Respiratory Syncytial Virus (RSV) Infections in Infants and Children in Hong Kong: Epidemiology and Disease Burden, The Inaugural Meeting of the Hong Kong RSV Concern Group, Hong Kong. 2011. |
| Chiu S.S.S., Chan K.H., Chen H., Young B.W., Lim W., Wong W.H.S. and Peiris J.S.M., Virologically Confirmed Population-Based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong, The Pediatric Infectious Disease Journal. 2010, 29: 000-000. |
| Chiu S.S.S., Chan K.H., Chen H., Young B.W.Y., Lim W., Wong W.H.S. and Peiris J.S.M., Virologically confirmed population-based burden of hospitalization caused by respiratory syncytial virus, adenovirus, and parainfluenza viruses in children in Hong Kong, The Pediatric Infectious Disease Journal [Epub ahead]. 2010, 29(12). |
| Cowling B.J., Ng S., Ma S.K., Cheng K.Y., Lim Wai W.S., Fang J., Chan K.H., Ip D.K.M., Chiu S.S.S., Peiris J.S.M. and Leung G.M., Protective Efficacy of Seasonal Influenza Vaccination against Seasonal and Pandemic Influenza Virus Infection during 2009 in Hong Kong, Clinical Infectious Diseases. 2010, 51(12): 1370-1379. |
| Cowling B.J., Ng S., Cheng K.Y., Wai W., Fang J., Chan K., Ma E., Ip D.K.M., Chiu S.S.S., Peiris J.S.M. and Leung G.M., The effectiveness of seasonal influenza vaccine in preventing pandemic and seasonal influenza infection: A randomized controlled trial (abstract), Options for the Control of Influenza VII Conference, 3-7 September 2010, Hong Kong. Hong Kong, Int’l Society for Influenza & Other Respiratory Virus Dis, 2010, 79-80. |
| Cowling B.J., Ng S., Cheng K.Y., Lim Wai W.S., Fang J., Chan K.H., Ma E.S.K., Ip D.K.M., Chiu S.S.S., Peiris J.S.M. and Leung G.M., The effectiveness of seasonal influenza vaccine in preventing pandemic and seasonal influenza infection: a randomized controlled trial (Options for the Control of Influenza VII, 3-7 September 2010, Hong Kong), Influenza and Other Respiratory Viruses. 2010, 5(Suppl 1): 328-332. |
| Ho P.L., Chiu S.S.S., Ang L. and Lau Y.L., Serotypes and antimicrobial susceptibilities of invasive Streptococcus pneumoniae before and after introduction of 7-valent pneumococcal conjugate vaccine, Hong Kong, 1995-2009., Vaccine. 2011, 29(17): 3270-3275. |
| Ho P.L., Ang L., Chow K.H., Lai E.L.Y. and Chiu S.S.S., The prevalence and characteristics of Streptococcus pneumoniae isolates expressing serotypes 6C and 6D in Hong Kong prior to the introduction of the 7-valent pneumococcal conjugate vaccine , Diagnostic Microbiology and Infectious Disease. 2010. |
| Lee S.L., Chiu S.S.S., Peiris J.S.M., Chan K.H., Wong W.H.S. and Lau Y.L., Is respiratory viral infection really an important trigger of asthma exacerbations in children?, Eur J Pediatr [Epub ahead]. 2011. |
| Ng S., Cheng K.Y., Lim Wai W.S., Fang J., Chan K.H., Ma S.K., Ip D.K.M., Chiu S.S.S., Peiris J.S.M., Leung G.M. and Cowling B.J., Seasonal influenza vaccine and risk of pandemic influenza infection: Findings from a randomized controlled trial (abstract and poster presentation), HKCCM International Conference, 4-6 September 2010, Hong Kong. Hong Kong, Hong Kong College of Community Medicine, 2010, 69. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Yang L., Chiu S.S.S., Chan K.P., Wong W.H.S., Peiris J.S.M. and Wong C.M., Validating statistical models for estimating disease burden of influenza and other respiratory viruses using virologically confirmed data (oral presentation), Options for the Control of Influenza VII Conference, 3-7 September 2010, Hong Kong. Hong Kong, Int’l Society for Influenza & Other Respiratory Virus Dis, 2010, 36. |
| Yang L., Chiu S.S.S., Chan K.P., Chan K.H., Wong W.H.S., Peiris J.S.M. and Wong C.M., Validation of statistical models for estimating hospitalization associated with influenza and other respiratory viruses, PLoS One. 2011, 6(3): e17882. |
| Researcher : Chong CY |
| List of Research Outputs |
| Lee P.P.W., Lee T.L., Ho M.H.K., Chong C.Y., So J.C.C. and Lau Y.L., An infant with severe congenital neutropenia presenting with persistent omphalitis: case report and literature review, Hong Kong Journal of Paediatrics (new series). 2010, 15: 289-298. |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Researcher : Chow CB |
| List of Research Outputs |
| Chow C.B., Ip P., Lee S.L., Tsang A.M.C., Chiu I., Wong W.H.S. and Lau Y.L., Policy brief: Children left unattended at home in Hong Kong , LC paper No. CB(2)1040/10-11(04), Welfare Services Panel, Legislative Council, Hong Kong, 17 Feb 2011. 2011. |
| Ip P., Chow C.B., Lee S.L., Tsang A.M.C., Chiu I.W.S., Wong W.H.S. and Lau Y.L., The need of policies and legislative changes for tobacco control in Hong Kong - Letter of recommendations to Hong Kong Legislative Council, LC paper No. No. CB(1)1768/10-11(07), Legislative Council, Hong Kong, 2 April 2011. , 2011. |
| Ip P., Chan E.K.L., Chow C.B., Wong W., Tsang A.M.C., Lee S.L. and Lau Y.L., Upsurging of child maltreatment admissions in Chinese by using ICD codes for maltreatment syndrome: A different experience in the East (Correspondence Letter) , Archives of Disease in Childhood (E publication 27 July 2010) . 2010. |
| Researcher : Chow PC |
| List of Research Outputs |
| Chung B.H.Y., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Chau A.K.T. and Lau Y.L., Two Chinese patients with Loeys-Dietz Syndrome due to TGFBR2 mutations, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Lai C.T.M., Chan K.W., Wong S.J., Chow P.C. and Cheung Y.F., Circulating levels of biomarkers of collagen synthesis correlate with left ventricular mechanical dyssynchrony in adolescents after repair of tetralogy of fallot (Abstract: Circulation 2010; 122:A12164), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Researcher : Chow WC |
| List of Research Outputs |
| Chow W.C., Ha S.Y. and Chan G.C.F., Vincristine can induce regression of vascular malformation in long standing refractory Kasabach Merritt Phenomenon. , HK J Paediatr (new series). 2011, 16: 121-1224. |
| Chow W.C., Ha S.Y. and Chan G.C.F., Vincristine can induce regression of vascular malformation in long standing refractory Kasabach Merritt Phenomenon. , Hong Kong Journal of Paediatrics. 2011;16:121-124.. 2011. |
| Researcher : Chu KM |
| List of Research Outputs |
| Lee P.P.W., Chan K.W., Chen T.X., Jiang L.P., Wang X.C., Zeng H.S., Chen X.Y., Liew W.K., Chen J., Chu K.M., Chan L.L., Shek L., Lee A.C.W., Yu H.H., Li Q., Xu C.G., Sultan-Ugdoracion G., Latiff Z.A., Latiff A.H.A., Jirapongsananuruk O., Ho M.H.K., Lee T.L., Yang X.Q. and Lau Y.L., Molecular diagnosis of severe combined immunodeficiency-identification of IL2RG, JAK3, IL7R, DCLRE1C, RAG1, and RAG2 mutations in a cohort of Chinese and southeast Asian Children, Journal of Clinical Immunology. 2011, 31: 281-296. |
| Researcher : Chu VLY |
| List of Research Outputs |
| Wong V.C.N., Cheuk D.K.L., Lee S. and Chu V.L.Y., Acupuncture for acute management and rehabilitation of traumatic brain injury. , Cochrane Database of Systematic Reviews 2011, Issue 5. Art. No.: CD007700. DOI: 10.1002/14651858.CD007700.pub2. . 2011. |
| Wong V.C.N. and Chu V.L.Y., Alternative therapy - TCM therapies. , In: JH Stone, M Blouin, editors., International Encyclopedia of Rehabilitation. Available online: http://cirrie.buffalo.edu/encyclopedia/en/article/325/. 2011. |
| Researcher : Chung BHY |
| Project Title: | Genetic studies on a multiplex Autism family in Hong Kong |
| Investigator(s): | Chung BHY, Yang W, Fung CW, Wong VCN |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2009 |
| Completion Date: | 12/2010 |
| Project Title: | CCMG 34th Annual Scientific Meeting Crosstalk between histone modifications and DNA methylation in patients with intellectual disability due to jardic mutations |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 10/2010 |
| Completion Date: | 10/2010 |
| Project Title: | A Pilot Study on Genome-Wide DNA Methylation Profiling in Systemic Lupus Erythematosus (SLE) |
| Investigator(s): | Chung BHY, Lau YL, Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2011 |
| List of Research Outputs |
| Chung B.H.Y., Stavropoulos J., Marshall C.R., Weksberg R., Scherer S.W. and Yoon G., 2q23 de novo microdeletion involving the MBD5 gene in a patient with developmental delay, post-natal microcephaly and distinct facial features, American Journal of Medical Genetics Part A. John Wiley & Sons, Inc, 2011, 155: 424-429. |
| Chung B.H.Y., Aetiology of ASD - can genetic studies help?, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. 2011. |
| Chung B.H.Y., Approach to skeletal dysplasia in prenatal setting, Maternal Fetal Medicine Meeting organized by QMH, QEH, PYNEH, TMH, 17 December 2010. 2010. |
| Chung B.H.Y., Shuman C., Choufani S. and Weksberg R., Beckwith-Wiedemann Syndrome, UpToDate Review. 2011, 19.1: 1-21. |
| Chung B.H.Y., Black Box of Genetic Counselling, Master of Genetic Counsellings, School of Nursing, 8 April 2011. 2011. |
| Chung B.H.Y., Case of the day - Embryo mix-up in art, Ethics in Medicine, Winter 2010/11. 2011, 13-16. |
| Chung B.H.Y., Chairman for Symposium 3: Epigenetics and Proteomics session, 9th Asia Pacific Conference on Human Genetics, HK, 30 November - 3 December 2010. 2010. |
| Chung B.H.Y., Grafodatskaya D., Butcher D.T., Scherer S.W., Abidi F.E., Schwartz C.E. and Wekserg R., Crosstalk between histone modification and DNA methylation in patients with intellectual disability syndrome due to JARID1C mutations, 1st Canadian Epigenetics Conference, London, Ontario, 4-7 May 2011 . 2011, 73. |
| Chung B.H.Y., Grafodatskaya D., Butcher D.T., Scherer S.W., Abidi F.E., Schwartz C.E. and Weksberg R., Crosstalk between histone modifications and DNA methylation in patients with intellectual disability due to JARID1C mutations, ASHG 2010 Annual Meeting, Washington, USA, 2-6 November 2010. |
| Chung B.H.Y., Crosstalk between histone modifications and DNA methylation in patients with intellectual disability due to JARID1C mutations, CCMG 34th Annual Scientific Meeting, Westin Nova Scotian, Halifax, Canada. 2010. |
| Chung B.H.Y., Crosstalk between histone modificiations and DNA methylation in patients with intellectual disability due to JARID1C mutations, Canadian College of Medical Genetics. 34th Annual Scientific Meeting, Halifax, Nova Scotia, 21-23 October 2010. [One of the top 4 submissions]. 2010. |
| Chung B.H.Y., Chu L., Forrest C., Silver R., Toi A., Blaser S., Viero S., Taylor G. and Chitayat D., Fetal forehead hemangiopericytoma: prenatal diagnosis and postnatal outcome, Ultrasound in Obstetrics and Gynecology [Letter to the Editor]. John Wiley & Sons, Ltd, 2010, 36(1): 121-124. |
| Chung B.H.Y., Shaffer L.G., Keating S., Johnson J., Casey B. and Chitayat D., From VACTEL-H to Heterotaxy: Variable Expressivity of ZIC3 - Related Disorders, American Journal of Medical Genetics (Part A). 2011, 155(5): 1123-1128. |
| Chung B.H.Y., Genetic Evaluation of Autism Spectrum Disorder, HA Commissioned Training for Paediatrics 2010 on "Neuro-behavioural Disorders & Neurodevelopmental Disabilities", 13 September 2010. 2010. |
| Chung B.H.Y., Genetic counselling after prenatal diagnosis, HA Commissioned Training in O&G 2011, QEH (28 Feb - 4 Mar 2011). 2011. |
| Chung B.H.Y., Genome-Wide epigenetic Profiling shows evidence of crosstalk between histone modification and DNA methylation in patients with intellectual disability syndrome due to JARID1C mutations, 9th Asia Pacific Conference on Human Genetics, HK, 30 November - 3 December 2010. |
| Chung B.H.Y., Genome-wide epigenetic profiling shows evidence of crosstalk between histone modifications and DNA methylation in patients with the intellectual disability syndrome due to JARID1C mutations, Best basic research in the Department of Paediatrics Annual Research Day. Hospital for Sick Children, Toronto, 23 October 2010. 2010. |
| Chung B.H.Y., In-vitro treatment with pravastain & dexamethasone normalizes abnormal deposition of elastic fibers in dermal fibroblasts derived from patients with restrictive dermopathy - possible therapeutic implications?, 31st Annual David W. Smith Workshop on Malformations and Morphogenesis, Seattle, USA, 27 August – 1 September 2010. [Fellow Award]. 2010. |
| Chung B.H.Y., In-vitro treatment with pravastatin and dexamethasone normalizes abnormal deposition of elastic fibers in dermal fibroblasts derived from patients with restrictive dermopathy - possible therapeutic implications, David W Smith Workshop on Malformations & Morphogenesis, Seattle, USA, 27 Aug - 1 Sept 2010. |
| Chung B.H.Y., Infantile systemic hyalinosis presenting as multiple joint pain in a Pakistani infant girl, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Chung B.H.Y., Member of the composition of the research team from HKU and publications of members related to Agamma and other primary mmunodeficiency. 2011. |
| Chung B.H.Y., Novel compound heterozygous mutations in the CYP11A1 gene in a boy with progressive adrenal insufficiency, Reviewer for Hong Kong Medical Journal. 2010. |
| Chung B.H.Y., Drmic I., Marshall C.R., Grafodatskaya D., Carter M., Fernandez B.A., Weksberg R., Roberts W. and Scherer S.W., Phenotypic spectrum associated with duplication of Xp11.22-p11.23 includes Autism Spectrum Disorder, European Journal of Medical Genetics. 2011, 54: e516-e520. |
| Chung B.H.Y., Response to "Releasing Genetic Information to Resarch Subjects" (Case of the day, Spring 2010) and to comments by Dr. Herman Tse (Fall 2010), Ethics in Medicine, Winter 2010/11. 2011. |
| Chung B.H.Y., Ring Chromosome 15 Syndrome: Case Report and Literature, Reviewer of Hong Kong Journal of Paediatrics. 2011. |
| Chung B.H.Y., The role of clinical geneticist in patients with neuro-genetic disorders, Paediatric Neurology Scientific Meeting, 24 February 2011. 2011. |
| Chung B.H.Y., The use of array comparative genomic hybridization in prenatal diagnosis, 9th Asia Pacific Conference on Human Genetics, HK, 30 Nov - 3 December 2010. |
| Chung B.H.Y., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Chau A.K.T. and Lau Y.L., Two Chinese patients with Loeys-Dietz Syndrome due to TGFBR2 mutations, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Chung B.H.Y., Two cases of borderline fetal ventriculomegaly, Maternal Fetal Medicine Seminar organized by Hong Kong Sanatorium Hospital & The Chinese University of Hong Kong, 30 June 2011. 2011. |
| Chung B.H.Y., Updated 3 times for Interesting case for Clinical Quiz, Case 16), 10 June, 10 July & 6 Oct, 2010. http://www.hku.hk/paed/student area/clinical quiz, 2010. |
| Chung B.H.Y., Vincristine Can Induce Regression of Vascular Malformation in Long Standing Regractory Kasabach Merritt Pheomenon, Reviewer of Hong Kong Journal of Paediatrics. 2011. |
| Grafodatskaya D., Chung B.H.Y., Szatmari P. and Weksberg R., Autism Spectrum Disorders and Epigenetics (with Editorial Comments), Journal of the American Academy of Child & Adolescent Psychiatry. 2010, 49(8): 794-809. |
| Hinek A., Chung B.H.Y., Teitelbaum R., Shannon P. and Chitayat D., In-vitro treatment with pravastatin and dexamethasone normalizes abnormal deposition of elastic fibers in dermal fibroblasts derived from patients with Restrictive Dermopathy – Possible therapeutic implications, ASHG 2010 Annual Meeting, Washington, USA, 2-6 November 2010. |
| Ho C.C., Liu A.P.Y., Lun K.S., Tam T., Chan K.K.L., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., 17p13.3 class I microduplication in a newborn with microcephaly, aortic stenosis and dysmorphic facial features, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Jessen J., Chung B.H.Y., Fernandez B., Li C. and Chitayat D., Ulnar-Mammary syndrome: Expending the phenotype to include ankyloglossia and cleft lip and palate, ASHG 2010 Annual Meeting, Washington, USA, 2-6 November 2010. |
| Liu A.P.Y., Ho C.C., Yung T.C., Tam T., Chan K.K.L., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., Inverted duplication 18q12.1-q22, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Shah V., Chung B.H.Y., Hinek A. and Chitayat D., Overgrowth with increased proliferation of fibroblast and matrix metalloproteinase activity related to reduced TIMP1: A new syndrome?, ASHG 2010 Annual Meeting, Washington, USA, 2-6 November 2010. |
| Wong V.C.N. and Chung B.H.Y., Value of clinical assessment in the diagnostic evaluation of Global Developmental Delay (GDD) using a Likelihood Ratio Model, Brain & Development. 2011, 33: 548-557. |
| Researcher : Dee CMA |
| List of Research Outputs |
| Gu Y., Dee C.M.A. and Shen J., Interaction of free radicals, matrix metalloproteinases and caveolin-1 impacts blood-brain barrier permeability in cerebral ischemia and reperfusion injury., Frontier in Bioscience. 2011, 3: 1216-1231. |
| Researcher : Fang JW |
| List of Research Outputs |
| Fang J.W., Li C.B., Au K.Y., Yim H.C.H. and Lau A.S.Y., Interleukin-17A differentially modulates BCG induction of cytokine production in human blood macrophages., Journal of Leukocyte Biology. 2011. |
| Li C.B., Au K.Y., Fang J.W., Yim H.C.H., Chow K.H., Ho P.L. and Lau A.S.Y., HIV-1 trans-activator protein dysregulates IFN-γ signaling and contributes to the suppression of autophagy induction., AIDS. 2011, 25(1): 15-25. |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Best Poster Presentation Award., Annual Scientific Meeting of the Hong Kong Society for Immunolgy. May 2011.. 2011. |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Interleukin 17 enhances innate immunity against mycobacterial infection in macrophages, Annual Scientific Meeting of Hong Kong Society for Immunology, May 2011. |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Interleulin 17 enhances innate immunity against mycobacterial infection in macrophages., Annual Scientific Meeting of the Hong Kong Society for Immunolgy. May 2011. # recipient of Best Poster Presentation Award.. 2011. |
| Researcher : Fung CW |
| List of Research Outputs |
| Chan S.H.S., Wong V.C.N., Fung C.W., Dale R.C. and Vincent A., Anti-NMDA Receptor Encephalitis With Atypical Brain Changes on MRI, Pediatric Neurology. 2010, 43(4): 274-278. |
| Fung C.W. and Wong V.C.N., Clinical profile of 13 children with severe myoclonic epilepsy of infancy in Hong Kong., 8th Asian & Oceanian Epilepsy Congress, Melbourne, Australia, 21-24 October. 2010. |
| Wong V.C.N. and Fung C.W., Spectrum of mitochondrial diseases in a tertiary referral centre in Hong Kong (poster), Hospital Authority Convention 2011, Hong Kong. 2011. |
| Yeung W.L., Wong V.C.N., Chan K.Y., Hui J., Fung C.W., Yau F.T., Ko C.H., Lam C.W., Mak C.M., Siu S. and Low L.C.K., Expanding Phenotype and Clinical Analysis of Tyrosine Hydroxylase Deficiency, J Child Neurol 2011 26(2): 179-187. 2011. |
| Researcher : Guan J |
| List of Research Outputs |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Researcher : Ha SY |
| List of Research Outputs |
| Chan G.C.F., Shing M.M.K., Yuen H.L., Li R.C.H., Li C.K., Ha S.Y. and Li C.K., Best Research Award (ASPR): The epidemiology of childhood brain tumors in Hong Kong report from the Hong Kong Pediatric Haematology Oncology Study Group., Pediatric Academic Societies and Asian Society for Pediatric Research 2011 Joint Meeting (PAS/ASPR 2011), Denver, Colorado, Apr 30-May 3, 2011.. 2011. |
| Chan G.C.F., Shing M.M.K., Yuen H.L., Li R.C.H., Li C.K., Ha S.Y. and Li C.K., The epidemiology of childhood brain tumors in Hong Kong report from the Hong Kong Pediatric Haematology Oncology Study Group., Pediatric Academic Societies and Asian Society for Pediatric Research 2011 Joint Meeting (PAS/ASPR 2011), Denver, Colorado, Apr 30-May 3, 2011. #Best Research Award (ASPR). 2011. |
| Cheuk D.K.L., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Ewing sarcoma family of tumors in children: experience of Queen Mary Hospital., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Outcomes of osteosarcoma in children: Experience of Queen Mary Hospital., 4th National Pediatric Surgical Oncology Conference and 4th Cross Strait Symposium on Pediatric Oncology, LKS Faculty of Medicine, The University of Hong Kong and Children’s Cancer Foundation, Hong Kong, November 5-6, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Chan G.C.F. and Ha S.Y., Outcomes of pediatric chronic myeloid leukemia: Experience of Queen Mary Hospital., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Cheuk D.K.L., Chiang A.K.S., Lee T.L., Chan G.C.F. and Ha S.Y., Vaccines for prophylaxis of viral infections in patients with hematological malignancies., Cochrane Database Syst Rev 3: CD006505. 2011. |
| Cheung J.S., Au W.Y., Ha S.Y., Kim D., Jensen J.H., Zhou Y., Cheung M.M.H., Wu Y., Guo H., Khong P.L., Brown T.R., Brittenham G.M. and Wu E.X., Reduced transverse relaxation rate (RRS) for improved sensitivity in monitoring myocardial iron in thalassaemia, Journal of Magnetic Resonance Imaging . 2011, 33: 1510-1516. |
| Cheung Y.F., Li S.N., Chan G.C.F., Wong S.J. and Ha S.Y., Left Ventricular Twisting and Untwisting Motion in Childhood Cancer Survivors, Echocardiography. 2011 May 25. doi: 10.1111/j.1540-8175.2011.01429.x. . 2011. |
| Cheung Y.F., Hong W., Chan G.C.F., Wong S.J. and Ha S.Y., Left ventricular myocaridal deformation and mechanical dyssynchrony in children with normal ventricular shortening fraction after anthracycline therapy, Heart. 2010, 96: 1137-1141. |
| Cheung Y.F., Liang X., Chan G.C.F., Wong S.J. and Ha S.Y., Myocardial iron load in patients with beta-thalassaemia major is associated with global left ventricular mechanical dyssynchrony (Abstract: Circulation 2010;122:A12192), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Chow W.C., Ha S.Y. and Chan G.C.F., Vincristine can induce regression of vascular malformation in long standing refractory Kasabach Merritt Phenomenon. , HK J Paediatr (new series). 2011, 16: 121-1224. |
| Chow W.C., Ha S.Y. and Chan G.C.F., Vincristine can induce regression of vascular malformation in long standing refractory Kasabach Merritt Phenomenon. , Hong Kong Journal of Paediatrics. 2011;16:121-124.. 2011. |
| Farrell J.J., Sherva R.M., Chen Z.Y., Luo H.Y., Chu B.F., Ha S.Y., Li C.K., Lee A.C., Li R.C., Li C.K., Yuen H.L., So J.C.C., Ma E.S.K., Chan L.C., Chan V.N.Y., Sebastiani P., Farrer L.A., Baldwin C.T., Steinberg M.H. and Chui D.H., A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression, Blood. 2011, 117(18): 4935-45. |
| Ha S.Y., Mok S.P., Lau Y.S., Rasalkar D.D., Cheuk D.K.L., Chiang A.K.S., Ho M.H.K. and Chan G.C.F., Intermediate term evaluation of a practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*, Hemoglobin 35(3):199-205. 2011. |
| Qiu D., Chan G., Chan Q., Ha S.Y. and Khong P.L., Susceptibility weighted MR imaging (SWI) for the evaluation of iron-loading in patients with β-thalassaemia major (TM), International Paediatric Radiology Congress, London, 27-31 May 2011.. 2011. |
| Ting J.Y., Chan S.Y., Lung D.C., Ho A.C.C., Chiang A.K.S., Ha S.Y., Tsoi N.S. and Chan G.C.F., Intra-abdominal Rhizopus microsporus Infection Successfully Treated by Combined Aggressive Surgical, Antifungal, and Iron Chelating Therapy, Journal of Pediatric Hematology Oncology. 2010, 32(6): e238-e240. |
| Xiong H., Zeng L.K., Ha S.Y., Chiang A.K.S., Cheuk D.K.L. and Chan G.C.F., A small cohort review of neonatal transient myeloproliferative disease in Chinese children. , HK J Paediatr (new series) 2011;16:258-63. 2011, 16: 258-263. |
| Xiong H., Ha S.Y., Chiang A.K.S., Cheuk D.K.L., Zeng L.K. and Chan G.C.F., A small cohort review of neonatal transient myeloproliferative disease in Chinese children, Hong Kong Journal of Paediatrics (new series). 2011, 16: 258-263. |
| Xiong H., Ha S.Y., Chiang A.K.S., Lau Y.L., Chan G.C.F. and Hu Q., Reversible leukoencephalopathy following intrathecal methotrexate. , HK J Paediatr (new series). 2010, 15: 327-331. |
| Zhang Z.Q., Chan G.C.F., Lam C.C.K., So J.C.C., Cheuk D.K.L., Chiang A.K.S. and Ha S.Y., The clinical features of Chinese children with von Willebrand disease: the experience of a tertiary institute., HK J Paediatr: 16:95-100, 2011. 2011. |
| Researcher : Hirankarn N |
| List of Research Outputs |
| Luo X., Yang W., Ye D.Q., Cui H., Zhang Y., Hirankarn N., Qian X., Tang Y., Lau Y.L., de Vries N., Tak P.P., Tsao B.P. and Shen N., A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus, PLos Genetic. 2011, 7(6): e1002128. |
| Researcher : Ho DNY |
| Project Title: | Mechanisms of Epstein-Barr Virus (EBV) microRNAs in maintaining viral latency |
| Investigator(s): | Ho DNY, Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2009 |
| Completion Date: | 05/2011 |
| Project Title: | 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases Kinetics of Epstein-Barr virus (EBV) latent and lytic protein expression in Burkitt, epithelial and lymphoblastoid cells upon lytic cycle induction |
| Investigator(s): | Ho DNY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 09/2010 |
| Completion Date: | 09/2010 |
| List of Research Outputs |
| Ho D.N.Y., Hui K.F. and Chiang A.K.S., Kinetics of Epstein-Barr virus (EBV) latent and lytic protein expression in EBV-positive Burkitt, epithelial and lymphoblastoid cells upon induction of lytic cycle, The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases. 2010. |
| Researcher : Ho MHK |
| List of Research Outputs |
| Chen J., Hu Y., Allen K.J., Ho M.H.K. and Li H., The prevalence of food allergy in infants in Chongqing, China, Pediatrics Allergy Immunology [Epub ahed of print]. 2011, doi:10/1111. |
| Ha S.Y., Mok S.P., Lau Y.S., Rasalkar D.D., Cheuk D.K.L., Chiang A.K.S., Ho M.H.K. and Chan G.C.F., Intermediate term evaluation of a practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*, Hemoglobin 35(3):199-205. 2011. |
| Ho M.H.K., Wong L.M., Ling S.C., Lee K.P., Cheng W.W., Hui J., Lau D.C.Y., Ng K.L., Wong D., Kwok K.L. and Kwan E.Y.W., Identifying the service gaps in the management of severe systemic allergic reaction/anaphylaxis by Paediatrics Departments of the the Hospital Authority, Hong Kong Journal of Paediatrics (new series). 2010, 15: 186-197. |
| Lee P.P.W., Lee T.L., Ho M.H.K., Chong C.Y., So J.C.C. and Lau Y.L., An infant with severe congenital neutropenia presenting with persistent omphalitis: case report and literature review, Hong Kong Journal of Paediatrics (new series). 2010, 15: 289-298. |
| Lee P.P.W., Chan K.W., Chen T.X., Jiang L.P., Wang X.C., Zeng H.S., Chen X.Y., Liew W.K., Chen J., Chu K.M., Chan L.L., Shek L., Lee A.C.W., Yu H.H., Li Q., Xu C.G., Sultan-Ugdoracion G., Latiff Z.A., Latiff A.H.A., Jirapongsananuruk O., Ho M.H.K., Lee T.L., Yang X.Q. and Lau Y.L., Molecular diagnosis of severe combined immunodeficiency-identification of IL2RG, JAK3, IL7R, DCLRE1C, RAG1, and RAG2 mutations in a cohort of Chinese and southeast Asian Children, Journal of Clinical Immunology. 2011, 31: 281-296. |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234. |
| Researcher : Hong W |
| List of Research Outputs |
| Cheung Y.F., Hong W., Chan G.C.F., Wong S.J. and Ha S.Y., Left ventricular myocaridal deformation and mechanical dyssynchrony in children with normal ventricular shortening fraction after anthracycline therapy, Heart. 2010, 96: 1137-1141. |
| Koh C., Hong W., Wong S.J. and Cheung Y.F., Systolic-diastolic coupling of myocardial deformation of the left ventricle in children with left ventricular noncompaction, Heart Vessels. 2010, 25: 493-499. |
| Researcher : Hui KF |
| List of Research Outputs |
| Ho D.N.Y., Hui K.F. and Chiang A.K.S., Kinetics of Epstein-Barr virus (EBV) latent and lytic protein expression in EBV-positive Burkitt, epithelial and lymphoblastoid cells upon induction of lytic cycle, The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases. 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and mediates enhanced apoptosis through activation of caspase-dependent pathway., 17th Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, November 3-5, 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid induces Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma and medicates enhanced apoptosis through activation of caspase-dependent pathway., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010 (oral presentation). 2010. |
| Hui K.F., Tsang C.M., Tsao G.S.W. and Chiang A.K.S., Suberoylanilide hydroxamic acid mediates enhanced apoptosis in nasopharyngeal carcinoma through induction of Epstein-Barr virus lytic cycle and activation of caspase-3., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Researcher : Ip P |
| Project Title: | Early Detoxification of Substance Abusing Mothers improves developmental and behavioural outcome of their children |
| Investigator(s): | Ip P, Chan EKL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2010 |
| List of Research Outputs |
| Chan E.K.L., Ip P., Wong W., Tsang A.M.C. and Lee S.L., Upsurging of child maltreatment admissions in Chinese by using ICD codes for maltreatment syndrome: A different experience in the East, Royal College of Paediatrics and Child Health, 2010. |
| Chan E.K.L., Fong D.Y.T., Yan E.C.W., Chow C.B. and Ip P., Validation of the Chinese Juvenile Victimization Questionnaire, Hong Kong Journal of Paediatrics. 2011, 16(1): 17-24. |
| Chow C.B., Ip P., Lee S.L., Tsang A.M.C., Chiu I., Wong W.H.S. and Lau Y.L., Policy brief: Children left unattended at home in Hong Kong , LC paper No. CB(2)1040/10-11(04), Welfare Services Panel, Legislative Council, Hong Kong, 17 Feb 2011. 2011. |
| Ip P., <東方日報醫健寶庫系列> Oriental Daily News - “Harm of Drug Abuse”(青少年濫藥對健康的影響) September 5, 2010 , 2010. |
| Ip P., A mixed outbreak of rubeola-rubella in District Kangra of Northern India, Hong Kong Journal of Paediatrics, May 2011, 2011. |
| Ip P., An 8-year-old boy with fever, severe bilateral calf pain and toe-walking, Hong Kong Medical Journal, July 2010, 2010. |
| Ip P., An 8-year-old boy with fever, severe bilateral calf pain and toe-walking, Hong Kong Medical Journal . 2010. |
| Ip P., Booklet Production for the "Explore the World of Medicine" Public Lecture Series 濫藥毀一生：對青少年健康的危害 2011, 2011. |
| Ip P., Building of Child Abuse Surveillance System in Hong Kong and Chinese Societies, Round Table Forum and Symposium on Child Protection in Chinese Societies, Hong Kong SAR China, June 28 - 29, 2011, 2011. |
| Ip P., Building of Child Abuse Surveillance System in Hong Kong and Chinese Societies, Round Table Forum and Symposium on Child Protection in Chinese Societies, Hong Kong SAR China, June 28 - 29, 2011 , 2011. |
| Ip P., Community-based Assessment for Memory and Motor Impairment among Young Substance Abusers using Standardized Instruments - A Hong Kong Experience , Hong Kong Journal of Paediatrics . 2010. |
| Ip P., Community-based Assessment for Memory and Motor Impairment among Young Substance Abusers using Standardized Instruments - A Hong Kong Experience, Hong Kong Journal of Paediatrics, Aug 2010. , 2010. |
| Ip P., Early Childhood Development and CCDS Program, Post-registration Certificate Course in the Core Module of the Child and Adolescent Nursing, Paediatric Intensive Care Nursing and Paediatric Oncology Nursing, 7 July 2010. 2010. |
| Ip P., Early Childhood Development and Early Life Intervention: Impact on Child Health, The 6th Asia-U.S. Partnership in Early Child Development in Primary Care, Manila, Philippines, May 18 - 20, 2011 , 2011. |
| Ip P., Enviornment and early child development, 12th Beijing/Hong Kong Medical Exchange - Children, Development, Environment. 17 October 2010, Hong Kong, 2010. |
| Ip P., Environment,child health and development, Multi-specialty medical mega conference (M3C), Hong Kong, 16-17 April 2011. 2011. |
| Ip P., Reviewer of Paper entitled "The Clinical Features of Chinese Children with von Willebrand Disease: The Experience of a Tertiary Institute", 2011. |
| Ip P., Substance Abuse Ruins One's Life - Harm and Impact to Adolescents' Health - "Explore the World of Medicine" Public Lecture Series, Hong Kong, September 11, 2010 , 2010. |
| Ip P., Substance abuse during pregnancy and teenage pregnancy , Hong Kong Christian Service, PS33 - Centre for Psychotropic Sustance Abusers. 17 Aug 2010, Hong Kong. 2010. |
| Ip P., Chow C.B., Lee S.L., Tsang A.M.C., Chiu I.W.S., Wong W.H.S. and Lau Y.L., The need of policies and legislative changes for tobacco control in Hong Kong - Letter of recommendations to Hong Kong Legislative Council, LC paper No. No. CB(1)1768/10-11(07), Legislative Council, Hong Kong, 2 April 2011. , 2011. |
| Ip P., Chan E.K.L., Chow C.B., Wong W., Tsang A.M.C., Lee S.L. and Lau Y.L., Upsurging of child maltreatment admissions in Chinese by using ICD codes for maltreatment syndrome: A different experience in the East (Correspondence Letter) , Archives of Disease in Childhood (E publication 27 July 2010) . 2010. |
| Ip P., 兒童肥胖症的成因及種類(一), 東方日報2011年5月8日. 2011. |
| Ip P., 兒童肥胖症的成因及種類(二), 東方日報, 2011年6月. 2011. |
| Ip P., 東方日報「醫健寶庫」系列: 青少年濫藥 可急性中毒死 05 Sept 2010., 2010. |
| Ip P., 玩得專注口水常流 - Ming Pao Daily News. Dec 15 2010, 2010. |
| Ip P., 食物標籤立法控制肥胖, 東方日報5月22日. 2011. |
| Ip P., “疑似肺炎 不用照肺？” 明報 (Ming Pao Daily News) 。 2010年9月19日., 2010. |
| Researcher : Kwan EYW |
| List of Research Outputs |
| Ho M.H.K., Wong L.M., Ling S.C., Lee K.P., Cheng W.W., Hui J., Lau D.C.Y., Ng K.L., Wong D., Kwok K.L. and Kwan E.Y.W., Identifying the service gaps in the management of severe systemic allergic reaction/anaphylaxis by Paediatrics Departments of the the Hospital Authority, Hong Kong Journal of Paediatrics (new series). 2010, 15: 186-197. |
| Researcher : Kwok H |
| List of Research Outputs |
| Kwok H. and Chiang A.K.S., Comparative analysis of Epstein-Barr virus (EBV) latent gene and microrna sequences among AKATA, B95.8, AG876 and GD1 EBV genomes., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Kwok H. and Chiang A.K.S., Comparison of Epstein-Barr virus (EBV) latent and microRNA gene sequences of Akata EBV genome to those of prototype EBV genomes., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010. |
| Researcher : Kwong KY |
| List of Research Outputs |
| Dong M., Si Y.Q., Sun S.Y., Pu X.P., Yang Z.J., Zhang L.R., Zhang L.H., Leung C.F.P., Lam M.C., Kwong K.Y., Yue J., Zhou Y., Kriksunov I.A., Hao Q. and Lee H.C., Design, synthesis and biological characterization of novel inhibitors of CD38., Org. Biomol. Chem.. 2011, 9: 3246-3257. |
| Researcher : Lai CTM |
| List of Research Outputs |
| Lai C.T.M., Chan K.W., Wong S.J., Chow P.C. and Cheung Y.F., Circulating levels of biomarkers of collagen synthesis correlate with left ventricular mechanical dyssynchrony in adolescents after repair of tetralogy of fallot (Abstract: Circulation 2010; 122:A12164), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Researcher : Lam BCC |
| List of Research Outputs |
| So C.C., Leung Y.Y., Yip S.F., Chan S.Y., Lam B.C.C., Chan G.C., Chim S. and Chan L.C., Common association of haemolytic uraemic syndrome with invasive Streptococcus, pneumoniae infection in five Chinese paediatric patients, Hong Kong Medical Journal [PMID 21636872, PubMed in process]. 2011, 17(3): 237-241. |
| Researcher : Lam KT |
| List of Research Outputs |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Researcher : Lau ASY |
| Project Title: | Cytokines, Signaling & Diseases 2003 The Role of Protein Kinase PKR in the Induction of Cytokine Expression by Bacillus Calmette Guerin Through NF-kappaB |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 10/2003 |
| Project Title: | Cytokine Dysregulation and Virus-Induced Cell Death in Avian Influenza Virus Infections |
| Investigator(s): | Lau ASY, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2005 |
| Project Title: | Immunomodulatory effects of Panax ginseng on Human Monocytic Cells |
| Investigator(s): | Lau ASY, Lee DCW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2007 |
| Project Title: | Roles of Autophagy in Host Immune Response to Influenza Virus Infection |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2008 |
| Project Title: | Factors affecting mycobacteria evasion of immunity: effects of HIV on cellular signaling and kinases |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 09/2009 |
| Project Title: | Cellular response to influenza virus infection: effect of autophagy versus apoptosis on virus replication |
| Investigator(s): | Lau ASY, Lee DCW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 10/2009 |
| Project Title: | Mycobacteria Evasion of Immunity: a Potential Role for IL-10 and its consequent Suppression of MHC Antigen Expression |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2009 |
| Project Title: | The 2nd International Conference on Regulatory T Cells and Th17 Cells and Clinical Application in Human Diseases Interleukin-17 Modulation of Mycobacterium-induced cytokine |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 07/2010 |
| Completion Date: | 07/2010 |
| Project Title: | A role for oncogenes in the regulation of immune response to Mycobacterial infection |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | Antiviral inhibitors against influenza virus replication |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2011 |
| List of Research Outputs |
| Chan L.L.Y., Cheung B.K.W., Li C.B. and Lau A.S.Y., Mycobacterial evasion of immunity: Induction of IL-10 and STAT3 in the downregulation of IFN-gamma-induced MHC class II molecule expression, 15th Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, 1-2 Dec. 2010. |
| Fang J.W., Li C.B., Au K.Y., Yim H.C.H. and Lau A.S.Y., Interleukin-17A differentially modulates BCG induction of cytokine production in human blood macrophages., Journal of Leukocyte Biology. 2011. |
| Lau A.S.Y. and Yang L.H., USA Patent Application #61/369,428: Uses of Cim-1 and Related Compounds for Treating Inflammation and Modulating Immune Responses. , Type: Provisional, Priority date for IP: 7/30/2010. (Assignee/owner: HKU). 2010. |
| Lau A.S.Y., Yang L.H., Chik S.C.C. and Law H.Y., USA Patent Application #61/390,279: Coriolus Versicolor Extracts, Methods of Preparation and Uses Thereof., Priority date for IP:6 Oct 2010. 2010. |
| Lee D.C.W. and Lau A.S.Y., Effects of Panax ginseng on tumor necrosis factor-α-mediated inflammation: a mini-review, Molecules. 2011 Mar 30;16(4):2802-16. 2011. |
| Li C.B., Au K.Y., Yim H.C.H. and Lau A.S.Y., HIV Tat in AIDS pathogenesis: dysregulation of pro-inflammatory and anti-inflammatory cytokines , ASBMB's Special Symposium "Recent Advances in Pathogenic Human Viruses". 2011. |
| Li C.B., Au K.Y., Fang J.W., Yim H.C.H., Chow K.H., Ho P.L. and Lau A.S.Y., HIV-1 trans-activator protein dysregulates IFN-γ signaling and contributes to the suppression of autophagy induction., AIDS. 2011, 25(1): 15-25. |
| Li C.B., Yim H.C.H. and Lau A.S.Y., Role of HIV-1 Tat in AIDS pathogenesis: its effects on cytokine dysregulation and contributions to the pathogenesis of opportunistic infection., AIDS. 2010, 24(11): 1609-23. |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Best Poster Presentation Award., Annual Scientific Meeting of the Hong Kong Society for Immunolgy. May 2011.. 2011. |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Interleukin 17 enhances innate immunity against mycobacterial infection in macrophages, Annual Scientific Meeting of Hong Kong Society for Immunology, May 2011. |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Interleulin 17 enhances innate immunity against mycobacterial infection in macrophages., Annual Scientific Meeting of the Hong Kong Society for Immunolgy. May 2011. # recipient of Best Poster Presentation Award.. 2011. |
| Or C.T., Yang L.H., Law H.Y., Li C.B. and Lau A.S.Y., Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia, Neuropharmacology 2011 May;60(6):823-31. Epub 2010 Dec 10. 2011. |
| Qi H., Tong Y., Lau A.S.Y. and Rong J., Neuroprotection by (Z)-ligustilide against oxygen and glucose deprivation/reperfusion injury: Involvement of heme oxygenase-1 induction via the activation of Nrf2 and PI3K/Akt pathways, The 14th Biennial International Amine Oxidase Workshop. 2010. |
| Qi H., Siu S.O., Chen Y., Han Y.F., Chu I.K., Tong Y., Lau A.S.Y. and Rong J., Senkyunolides reduce hydrogen peroxide-induced oxidative damage in human liver HepG2 cells via induction of heme oxygenase-1, Chemico-Biological Interactions. 2011, 183(3): 380-389. |
| Wang L., Yang L.H., Or C.T., Chen G., Zhou J., Li C.B. and Lau A.S.Y., Differential effects of Radix Paeoniae Rubra (Chishao) on cytokine and chemokine expression inducible by mycobacteria, Chin Med. 2011 Mar 30;6(1):14. 2011. |
| Wang L., Yang L.H., Or C.T., Li C.B. and Lau A.S.Y., Differential effects of radix paeoniae rubra on cytokine and chemokine expression inducible by mycobacterium., 9th Meetinhg of Consortium for Globalization of Chinese Medicine (CGCM), Hong Kong, August 23-25,. 2010. |
| Wei L., Liu J., Le X.C., Han Y., Tong Y., Lau A.S.Y. and Rong J., Pharmacological induction of leukotriene B4-12-hydroxydehydrogenase suppresses the oncogenic transformation of human hepatoma HepG2 cells, International Journal of Oncology. Athens, Greece, Spandidos Publications Ltd, 2011, 39: 735-745. |
| Yim H.C.H., Li C.B. and Lau A.S.Y., Dual-Specificity Protein Phosphatase-1 Positively Regulates The Anti-Mycobacterial Responses, 1st Lorne Infection and Immunity Conference Feb 16-18, . Lorne, Victoria, Australia, 2011, 112. |
| Researcher : Lau DCY |
| List of Research Outputs |
| Ho M.H.K., Wong L.M., Ling S.C., Lee K.P., Cheng W.W., Hui J., Lau D.C.Y., Ng K.L., Wong D., Kwok K.L. and Kwan E.Y.W., Identifying the service gaps in the management of severe systemic allergic reaction/anaphylaxis by Paediatrics Departments of the the Hospital Authority, Hong Kong Journal of Paediatrics (new series). 2010, 15: 186-197. |
| Researcher : Lau YL |
| Project Title: | A community-based educational program on thalassaemias to enhance awareness with the aim to reduce burden of thalassaemia related health problems in Hong Kong |
| Investigator(s): | Lau YL, Ha SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health Promotion Projects |
| Start Date: | 09/1997 |
| Project Title: | Comparison of process upgrade varicella vaccine (Puvv) with VARILRIX-TM |
| Investigator(s): | Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/1999 |
| Project Title: | Association of cytokine and chemokine genes polymorphism with susceptibility to SARS and severity of SARS |
| Investigator(s): | Lau YL, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 09/2005 |
| Project Title: | p21 gene polymorphism with systemic lupus erythematosus and rheumatoid arthritis |
| Investigator(s): | Lau YL, Lau WCS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2005 |
| Project Title: | Association of STAT4, ITGAM, BLK and PXK gene polymorphisms with systemic lupus erythematosus (SLE) |
| Investigator(s): | Lau YL, Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2008 |
| Project Title: | Immune Responses to Influenza Viruses in the Patients with X-linked Agammaglobulinemia |
| Investigator(s): | Lau YL, Tu W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2008 |
| Completion Date: | 03/2011 |
| Project Title: | Case-control study of Sichuan and Hong Kong children with melamine associated renal stones - renal ultasounds and urinary IL-8 and MCP-1 |
| Investigator(s): | Lau YL, Tu W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Studies Related to Melamine Incident |
| Start Date: | 04/2009 |
| Completion Date: | 09/2010 |
| Project Title: | Functional characterization of two genetic variants associated with SLE identified in the Hong Kong SLE collection |
| Investigator(s): | Lau YL, Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2010 |
| Completion Date: | 12/2010 |
| Project Title: | Serum cytokine profiles of SLE patients and their correlations to susceptibility genes |
| Investigator(s): | Lau YL, Yang W, Zhang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2010 |
| Completion Date: | 10/2011 |
| Project Title: | Pediatric Academic Societies and Asian Society for Pediatric Research 2011 Joint Meeting Invited lecture on "Promoting PID care in Asia with e-based consultation and free genetic diagnostic service" |
| Investigator(s): | Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 04/2011 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Chow C.B., Ip P., Lee S.L., Tsang A.M.C., Chiu I., Wong W.H.S. and Lau Y.L., Policy brief: Children left unattended at home in Hong Kong , LC paper No. CB(2)1040/10-11(04), Welfare Services Panel, Legislative Council, Hong Kong, 17 Feb 2011. 2011. |
| Chung B.H.Y., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Chau A.K.T. and Lau Y.L., Two Chinese patients with Loeys-Dietz Syndrome due to TGFBR2 mutations, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Ho P.L., Chiu S.S.S., Ang L. and Lau Y.L., Serotypes and antimicrobial susceptibilities of invasive Streptococcus pneumoniae before and after introduction of 7-valent pneumococcal conjugate vaccine, Hong Kong, 1995-2009., Vaccine. 2011, 29(17): 3270-3275. |
| Ip P., Chow C.B., Lee S.L., Tsang A.M.C., Chiu I.W.S., Wong W.H.S. and Lau Y.L., The need of policies and legislative changes for tobacco control in Hong Kong - Letter of recommendations to Hong Kong Legislative Council, LC paper No. No. CB(1)1768/10-11(07), Legislative Council, Hong Kong, 2 April 2011. , 2011. |
| Ip P., Chan E.K.L., Chow C.B., Wong W., Tsang A.M.C., Lee S.L. and Lau Y.L., Upsurging of child maltreatment admissions in Chinese by using ICD codes for maltreatment syndrome: A different experience in the East (Correspondence Letter) , Archives of Disease in Childhood (E publication 27 July 2010) . 2010. |
| Lau Y.L., Allogeneic Hematopoietic Stem Cell Transplantation for Primary Immunodeficiencies, 15th Congress of the Asia Pacific Blood and Marrow Transplantation, Phuket. 2010. |
| Lau Y.L., Asian Network for Molecular Diagnosis of Primary Immunodeficiences, Century Celebration of WCUMS and The 10th Anniversary of WCUMS-SCU Merger, Chengdu. 2010. |
| Lau Y.L., Juvenile Idiopathic Arthritis, 兒科顧問計劃, 澳門仁伯爵綜合醫院, Macau. 2010. |
| Lau Y.L., Juvenile Idiopathic Arthritis, 謝貴雄教授紀念學術演講會暨台灣兒童過敏氣喘及免疫學會第五屆第二次會員大會, 高雄. 2010. |
| Lau Y.L., Molecular diagnosis of Primary Immunodeficiency, 8th Asia Pacific Congress of Allergy, Asthma and Clinical Immunology, Singapore. 2010. |
| Lau Y.L., Pandemic Swine Flu, Pediatric Seminar 2010, Macau Bureau of Health, Macau. 2010. |
| Lau Y.L., Primary Immunodeficiencies, International Forum of Pediatric Intractable Diseases, Tokyo. 2010. |
| Lau Y.L., Promoting PID Care in Asia with E-based Consultation and Free Genetic Diagnostic Service, Pediatric Academic Societies and Asian Society for Pediatric Research, Denver. 2011. |
| Lau Y.L., Promoting PID care in Asia with E-based consultation and free genetic diagnostic service, International Pediatric Congress, Johannesburg. 2010. |
| Lau Y.L., Recent top papers in translational medicine, 29th Annual Meeting of the European Society for Paediatric Infectious Disease (ESPID), Hague, Netherlands. 2011. |
| Lau Y.L., Systemic Lupus Erythematosus, 兒科顧問計劃, 澳門仁伯爵綜合醫院, Macau. 2010. |
| Lau Y.L., Understanding Immunology through Primary Immunodeficiency diseases, 8th Asia Pacific Congress of Allergy, Asthma and Clinical Immunology, Singapore. 2010. |
| Lau Y.L., Where in the World Are We?, World Immunology Conference, New York. 2011. |
| Lau Y.L., 幼年特發性關節炎之診斷及治療, 粵港兒童免疫風濕病病友交流會, 廣州. 2010. |
| Lee P.P.W., Lee T.L., Ho M.H.K., Chong C.Y., So J.C.C. and Lau Y.L., An infant with severe congenital neutropenia presenting with persistent omphalitis: case report and literature review, Hong Kong Journal of Paediatrics (new series). 2010, 15: 289-298. |
| Lee P.P.W., Chan K.W., Chen T.X., Jiang L.P., Wang X.C., Zeng H.S., Chen X.Y., Liew W.K., Chen J., Chu K.M., Chan L.L., Shek L., Lee A.C.W., Yu H.H., Li Q., Xu C.G., Sultan-Ugdoracion G., Latiff Z.A., Latiff A.H.A., Jirapongsananuruk O., Ho M.H.K., Lee T.L., Yang X.Q. and Lau Y.L., Molecular diagnosis of severe combined immunodeficiency-identification of IL2RG, JAK3, IL7R, DCLRE1C, RAG1, and RAG2 mutations in a cohort of Chinese and southeast Asian Children, Journal of Clinical Immunology. 2011, 31: 281-296. |
| Lee S.L., Chiu S.S.S., Peiris J.S.M., Chan K.H., Wong W.H.S. and Lau Y.L., Is respiratory viral infection really an important trigger of asthma exacerbations in children?, Eur J Pediatr [Epub ahead]. 2011. |
| Li J., Law H.K.W., Lau Y.L. and Chan G.C.F., Effect of Cisplatin, Hydroxyurea, Topotecan and Daunorubicin on Human Mesenchymal Stem Cells, Journal of Experimental Hematology. 2010, 18(4): 991-996. |
| Li P., Chang Y.K., Shek K.W. and Lau Y.L., Lack of association of TYK2 gene polymorphisms in Chinese patients with systemic lupus erythematosus, Journal of Rheumatology. 2011, 38: 177-178. |
| Li R., Yang W., Yang J. and Lau Y.L., Association of CD247 with systemic lupus erythematosus in Asian Populations: A genome wide association study , Lupus. . 2011. |
| Luo X., Yang W., Ye D.Q., Cui H., Zhang Y., Hirankarn N., Qian X., Tang Y., Lau Y.L., de Vries N., Tak P.P., Tsao B.P. and Shen N., A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus, PLos Genetic. 2011, 7(6): e1002128. |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Niederer H.A., Willcocks L.C., Rayner T.F., Yang W., Lau Y.L., Williams T.N., Scott J.A.G., Urban B.C., Peshu N., Dunstan S.J., Hien T.T., Phu N.H., Padyukov L., Gunnarsson I., Svenungsson E., Savage C.O., Watts R.A., Lyons P.A., Clayton D.G. and Smith K.G.C., Copy number, linkage disequilibrium and disease association in the FCGR locus, Human Molecular Genetics. 2010, 19(6): 3282-3294. |
| Shen N., Fu Q., Deng Y., Qian X., Zhao J., Kaufman K.M., Wu Y.L., Yu C.Y., Tang Y., Chen J.Y., Yang W., Wong M., Kawasaki A., Tsuchiya N., Sumida T., Kawaguchi Y., Howes H.S., Mok T.M.Y., Bang S.Y., Liu F.L., Chang D.M., Takasaki Y., Hashimoto H., Harley J.B., Guthridge J.M., Grossman J.M., Cantor R.M., Song Y.W., Bae S.C., Chen S., Hahn B.H., Lau Y.L. and Tsao B.P., Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus, Proceeding of the National Academy of Sciences USA. 2010, 2010: 107(36). |
| Tu W., Mao H., Qin G., Zhang J. and Lau Y.L., Challenges and opportunities from the pandemic influenza A (H1N1), Chinese Journal of Pediatrics. 2010, 48: 561-563. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Wang Z., Luo H., Tu W., Yang H., Wong W.H.S., Wong W.T., Yung K.F., Zhou N., Zhang J., Li X., Wang Z., Guo W., Mu D., Li F., Mao M. and Lau Y.L., Melamine-tainted milk products associated urinary stones in children, Pediatrics International. 2010, doi: 10.1111/j. |
| Wu J.T.K., Ma S.K., Lee C.K., Chu K.W., Ho P.L., Shen L., Ho W.K., Hung I.F.N., Riley S., Ho L.M., Lin C.K., Tsang T.H.F., Lo S.V., Lau Y.L., Leung G.M., Cowling B.J. and Peiris J.S.M., A serial cross-sectional serologic survey of 2009 Pandemic (H1N1) in Hong Kong: implications for future pandemic influenza surveillance (Options for the Control of Influenza VII, 3-7 September 2010, Hong Kong), Influenza and Other Respiratory Viruses. 2011, 5(Suppl 1): 190-194. |
| Wu J.T.K., Cowling B.J., Riley S., Peiris J.S.M., Ma E., Lee K., Hung I.F.N., Lau Y.L., Lo S.V. and Leung G.M., A serial cross-sectional serologic survey of 2009 pandemic (H1N1) in Hong Kong: Implications for future pandemic influenza surveillance (abstract), Options for the Control of Influenza VII Conference, 3-7 September 2010, Hong Kong. Hong Kong, Int’l Society for Influenza & Other Respiratory Virus Dis, 2010, 256. |
| Wu J.T.K., Ma S.K., Lee C.K., Chu K.W., Ho P.L., Shen L., Ho W.K., Hung I.F.N., Riley S., Ho L.M., Lin C.K., Tsang T.H.F., Lo S.V., Lau Y.L., Leung G.M., Cowling B.J. and Peiris J.S.M., The infection attack rate and severity of 2009 pandemic H1N1 influenza in Hong Kong, Clinical Infectious Diseases. 2010, 51(10): 1184-1191. |
| Xiong H., Ha S.Y., Chiang A.K.S., Lau Y.L., Chan G.C.F. and Hu Q., Reversible leukoencephalopathy following intrathecal methotrexate. , HK J Paediatr (new series). 2010, 15: 327-331. |
| Yang J., Yang W. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, American society of human genetics, 2010 . 2010. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Yang W., Li R., Yang J., Ye D.Q. and Lau Y.L., Genome-Wide Assocation Studies in Hong Kong identified Novel Susceptibility Genes for Systemic Lupus Erythematosus, American Society of Human Genetics, 2010. |
| Zhang L., Yang W., Ying D., Cherny S.S., Hildebrandt F., Sham P.C. and Lau Y.L., Homozygosity Mapping on a Single Patient-Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data, Human Mutation. 2011, 32 (3): 345-353. |
| Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234. |
| Researcher : Lau YS |
| List of Research Outputs |
| Ha S.Y., Mok S.P., Lau Y.S., Rasalkar D.D., Cheuk D.K.L., Chiang A.K.S., Ho M.H.K. and Chan G.C.F., Intermediate term evaluation of a practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*, Hemoglobin 35(3):199-205. 2011. |
| Researcher : Law HKW |
| List of Research Outputs |
| Li J., Law H.K.W., Lau Y.L. and Chan G.C.F., Effect of Cisplatin, Hydroxyurea, Topotecan and Daunorubicin on Human Mesenchymal Stem Cells, Journal of Experimental Hematology. 2010, 18(4): 991-996. |
| Researcher : Law HY |
| List of Research Outputs |
| Lau A.S.Y., Yang L.H., Chik S.C.C. and Law H.Y., USA Patent Application #61/390,279: Coriolus Versicolor Extracts, Methods of Preparation and Uses Thereof., Priority date for IP:6 Oct 2010. 2010. |
| Or C.T., Yang L.H., Law H.Y., Li C.B. and Lau A.S.Y., Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia, Neuropharmacology 2011 May;60(6):823-31. Epub 2010 Dec 10. 2011. |
| Researcher : Lee DCW |
| List of Research Outputs |
| Lee D.C.W. and Lau A.S.Y., Effects of Panax ginseng on tumor necrosis factor-α-mediated inflammation: a mini-review, Molecules. 2011 Mar 30;16(4):2802-16. 2011. |
| Researcher : Lee KP |
| List of Research Outputs |
| Wong S.N., Tse K.C., Lee K.P., Yuen S.F., Leung L.C., Pau B.C., Chan W.K., Lee K.W., Cheung H.M., Chim S. and Yip C.M., Evaluating different imaging strategies in children after first febrile urinary tract infection, Pediatric Nephrology. 2010, 25(10): 2083-2091. |
| Researcher : Lee PPW |
| List of Research Outputs |
| Lee P.P.W., Lee T.L., Ho M.H.K., Chong C.Y., So J.C.C. and Lau Y.L., An infant with severe congenital neutropenia presenting with persistent omphalitis: case report and literature review, Hong Kong Journal of Paediatrics (new series). 2010, 15: 289-298. |
| Lee P.P.W., Chan K.W., Chen T.X., Jiang L.P., Wang X.C., Zeng H.S., Chen X.Y., Liew W.K., Chen J., Chu K.M., Chan L.L., Shek L., Lee A.C.W., Yu H.H., Li Q., Xu C.G., Sultan-Ugdoracion G., Latiff Z.A., Latiff A.H.A., Jirapongsananuruk O., Ho M.H.K., Lee T.L., Yang X.Q. and Lau Y.L., Molecular diagnosis of severe combined immunodeficiency-identification of IL2RG, JAK3, IL7R, DCLRE1C, RAG1, and RAG2 mutations in a cohort of Chinese and southeast Asian Children, Journal of Clinical Immunology. 2011, 31: 281-296. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234. |
| Researcher : Lee SL |
| List of Research Outputs |
| Chow C.B., Ip P., Lee S.L., Tsang A.M.C., Chiu I., Wong W.H.S. and Lau Y.L., Policy brief: Children left unattended at home in Hong Kong , LC paper No. CB(2)1040/10-11(04), Welfare Services Panel, Legislative Council, Hong Kong, 17 Feb 2011. 2011. |
| Ip P., Chow C.B., Lee S.L., Tsang A.M.C., Chiu I.W.S., Wong W.H.S. and Lau Y.L., The need of policies and legislative changes for tobacco control in Hong Kong - Letter of recommendations to Hong Kong Legislative Council, LC paper No. No. CB(1)1768/10-11(07), Legislative Council, Hong Kong, 2 April 2011. , 2011. |
| Ip P., Chan E.K.L., Chow C.B., Wong W., Tsang A.M.C., Lee S.L. and Lau Y.L., Upsurging of child maltreatment admissions in Chinese by using ICD codes for maltreatment syndrome: A different experience in the East (Correspondence Letter) , Archives of Disease in Childhood (E publication 27 July 2010) . 2010. |
| Lee S.L., Chiu S.S.S., Peiris J.S.M., Chan K.H., Wong W.H.S. and Lau Y.L., Is respiratory viral infection really an important trigger of asthma exacerbations in children?, Eur J Pediatr [Epub ahead]. 2011. |
| Researcher : Lee TL |
| List of Research Outputs |
| Cheuk D.K.L., Chiang A.K.S., Lee T.L., Chan G.C.F. and Ha S.Y., Vaccines for prophylaxis of viral infections in patients with hematological malignancies., Cochrane Database Syst Rev 3: CD006505. 2011. |
| Lee P.P.W., Lee T.L., Ho M.H.K., Chong C.Y., So J.C.C. and Lau Y.L., An infant with severe congenital neutropenia presenting with persistent omphalitis: case report and literature review, Hong Kong Journal of Paediatrics (new series). 2010, 15: 289-298. |
| Lee P.P.W., Chan K.W., Chen T.X., Jiang L.P., Wang X.C., Zeng H.S., Chen X.Y., Liew W.K., Chen J., Chu K.M., Chan L.L., Shek L., Lee A.C.W., Yu H.H., Li Q., Xu C.G., Sultan-Ugdoracion G., Latiff Z.A., Latiff A.H.A., Jirapongsananuruk O., Ho M.H.K., Lee T.L., Yang X.Q. and Lau Y.L., Molecular diagnosis of severe combined immunodeficiency-identification of IL2RG, JAK3, IL7R, DCLRE1C, RAG1, and RAG2 mutations in a cohort of Chinese and southeast Asian Children, Journal of Clinical Immunology. 2011, 31: 281-296. |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234. |
| Researcher : Leung CSY |
| List of Research Outputs |
| Chan A.S., Han Y.M.Y., Leung W.W.M., Leung C.S.Y., Wong V.C.N. and Cheung M.C., Abnormalities in the anterior cingulate cortex associated with attentional and inhibitory control deficits: A neurophysiological study on children with autism spectrum disorders, Research in Autism Spectrum Disorders. 2011, 5(1): 254-266. |
| Researcher : Li CB |
| Project Title: | Enhancement of innate immunity to the pathogen infection: anti-mycobacterial effect of IL-17 |
| Investigator(s): | Li CB, Lau ASY |
| Department: | Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 12/2009 |
| Project Title: | 2010 Joint Meeting between Society of Leukocyte Biology and the International Endotoxin and Innate Immunity Society IL-17 enhances mycobacterium induction of IL-6 expression in human primary blood macrophages |
| Investigator(s): | Li CB |
| Department: | Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 10/2010 |
| Completion Date: | 10/2010 |
| Project Title: | Anti-oxidative effects and the underlying mechanisms of Ligusticum chuanxiong in neuronal cells |
| Investigator(s): | Li CB, Lau ASY |
| Department: | Medical Faculty |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Chan L.L.Y., Cheung B.K.W., Li C.B. and Lau A.S.Y., Mycobacterial evasion of immunity: Induction of IL-10 and STAT3 in the downregulation of IFN-gamma-induced MHC class II molecule expression, 15th Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, 1-2 Dec. 2010. |
| Fang J.W., Li C.B., Au K.Y., Yim H.C.H. and Lau A.S.Y., Interleukin-17A differentially modulates BCG induction of cytokine production in human blood macrophages., Journal of Leukocyte Biology. 2011. |
| Li C.B., Au K.Y., Fang J.W., Yim H.C.H., Chow K.H., Ho P.L. and Lau A.S.Y., HIV-1 trans-activator protein dysregulates IFN-γ signaling and contributes to the suppression of autophagy induction., AIDS. 2011, 25(1): 15-25. |
| Or C.T., Yang L.H., Law H.Y., Li C.B. and Lau A.S.Y., Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia, Neuropharmacology 2011 May;60(6):823-31. Epub 2010 Dec 10. 2011. |
| Wang L., Yang L.H., Or C.T., Chen G., Zhou J., Li C.B. and Lau A.S.Y., Differential effects of Radix Paeoniae Rubra (Chishao) on cytokine and chemokine expression inducible by mycobacteria, Chin Med. 2011 Mar 30;6(1):14. 2011. |
| Researcher : Li J |
| List of Research Outputs |
| Li J., Law H.K.W., Lau Y.L. and Chan G.C.F., Effect of Cisplatin, Hydroxyurea, Topotecan and Daunorubicin on Human Mesenchymal Stem Cells, Journal of Experimental Hematology. 2010, 18(4): 991-996. |
| Researcher : Li Q |
| List of Research Outputs |
| Wong K.K., Li Q., Wong H.T., Tsang K.H., Lai S.K., McAlonan G.M., Chan Y.S. and Chan S.Y., TSPYL2 regulates CREB-Dependent Gene Expression, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2079. |
| Researcher : Li R |
| List of Research Outputs |
| Yang W., Li R., Yang J., Ye D.Q. and Lau Y.L., Genome-Wide Assocation Studies in Hong Kong identified Novel Susceptibility Genes for Systemic Lupus Erythematosus, American Society of Human Genetics, 2010. |
| Researcher : Li S |
| List of Research Outputs |
| Li S., Wong S.J. and Cheung Y.F., Left ventricular eccentricity impairs three-dimensional systolic radial strain and torsion in patients after repair of tetralogy of fallot: a three-dimensional speckle tracking analysis (Abstract: Circulation 2010; 122:A10455), American Heart Association Scientific Sessions 2010, Chicago, 13-17 November 2010. |
| Researcher : Liang X |
| List of Research Outputs |
| Cheung Y.F., Liang X., Chan G.C.F., Wong S.J. and Ha S.Y., Myocardial iron load in patients with beta-thalassaemia major is associated with global left ventricular mechanical dyssynchrony (Abstract: Circulation 2010;122:A12192), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Liang X., Chiu P.H., Yip K.Y. and Chan S.Y., Subcellular localization of SUN2 regulated by lamin A and rab5, PLoS One. 2011, 6(5): e20507. |
| Researcher : Ling SC |
| List of Research Outputs |
| Ho M.H.K., Wong L.M., Ling S.C., Lee K.P., Cheng W.W., Hui J., Lau D.C.Y., Ng K.L., Wong D., Kwok K.L. and Kwan E.Y.W., Identifying the service gaps in the management of severe systemic allergic reaction/anaphylaxis by Paediatrics Departments of the the Hospital Authority, Hong Kong Journal of Paediatrics (new series). 2010, 15: 186-197. |
| Researcher : Ling WL |
| List of Research Outputs |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Best Poster Presentation Award., Annual Scientific Meeting of the Hong Kong Society for Immunolgy. May 2011.. 2011. |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Interleukin 17 enhances innate immunity against mycobacterial infection in macrophages, Annual Scientific Meeting of Hong Kong Society for Immunology, May 2011. |
| Ling W.L., Fang J.W., Yim H.C.H., Lau A.S.Y. and Li C.B., Interleulin 17 enhances innate immunity against mycobacterial infection in macrophages., Annual Scientific Meeting of the Hong Kong Society for Immunolgy. May 2011. # recipient of Best Poster Presentation Award.. 2011. |
| Researcher : Liu APY |
| List of Research Outputs |
| Ho C.C., Liu A.P.Y., Lun K.S., Tam T., Chan K.K.L., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., 17p13.3 class I microduplication in a newborn with microcephaly, aortic stenosis and dysmorphic facial features, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Liu A.P.Y., Ho C.C., Yung T.C., Tam T., Chan K.K.L., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., Inverted duplication 18q12.1-q22, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Researcher : Liu Y |
| List of Research Outputs |
| Liu Y., Tu W. and Lau Y.L., Dendritic cell function and T cell responses to influenza viruses in patients with X-Linked agammaglobulinemia, iImmunology 2011. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Zheng J., Liu Y., Tu W. and Lau Y.L., Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway, Eur J Immunol. 2011 Jan;41(1):128-39.. 2011. |
| Researcher : Liu Y |
| List of Research Outputs |
| Liu Y., Tu W. and Lau Y.L., Dendritic cell function and T cell responses to influenza viruses in patients with X-Linked agammaglobulinemia, iImmunology 2011. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Zheng J., Liu Y., Tu W. and Lau Y.L., Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway, Eur J Immunol. 2011 Jan;41(1):128-39.. 2011. |
| Researcher : Low LCK |
| Project Title: | 12th Asia Pacific Congress of Paediatrics and 2nd Asia Pacific Congress of Paediatric Nursing The Role of Nutritional Intake and Total Energy Expenditure on Early Growth of Babies Born with Intrauterine Growth Retardation |
| Investigator(s): | Low LCK |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 09/2006 |
| List of Research Outputs |
| Low L.C.K., 12th Fellows Meeting, Asia Pacific Paediatric Endocrine Society, Xian, China 14 - 17 November , 2010. |
| Low L.C.K., Childhood obesity in developing countries , World Journal of Pediatrics (Editorial) . 2010, 6: 197-199. |
| Low L.C.K., Common Paediatric Endocrine Problems, CME lecture in Paediatrics at Canossa Hospital (Caritas), Hong Kong, 29 June 2011, 2011. |
| Low L.C.K., Congenital Adrenal Hyperplasia: The Problems Encountered, 7th Asia Pacific Regional Meeting of the International Society for Neonatal Screening, Bali 03-05 October,2010. 2010. |
| Low L.C.K., Congenital adrenal hyperplasia: the problems encountered , Paediatrica Indonesiana . 2010, 50: No.5 (Suppl). |
| Low L.C.K., Neonatal Resuscitation Program (NRP) Preparatory Visit to GuiZhou, 4 - 8 September, 2010, 2010. |
| Low L.C.K., Newborn screening for congenital hypothyroidism in premature infants , Paediatrica Indonesiana . 2010, 50: No.5 (Suppl). |
| Low L.C.K., Newborn screening for congenital hypothyroidism in premature infants, 7th Asia Pacific Regional Meeting of the International Society for Neonatal Screening, Bali, 03-05 October, 2010. 2010. |
| Low L.C.K., Silver Russell <聚焦生長障礙> 第二期雜誌組稿會, Beijing, China 17 -18 July, 2010. |
| Low L.C.K., Silver-Russell (綜合症) <聚焦生長障礙> 第二期雜誌組稿會, Beijing, China 17 18 July , 2010. |
| Yeung W.L., Wong V.C.N., Chan K.Y., Hui J., Fung C.W., Yau F.T., Ko C.H., Lam C.W., Mak C.M., Siu S. and Low L.C.K., Expanding Phenotype and Clinical Analysis of Tyrosine Hydroxylase Deficiency, J Child Neurol 2011 26(2): 179-187. 2011. |
| Researcher : Lun KS |
| List of Research Outputs |
| Chung B.H.Y., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Chau A.K.T. and Lau Y.L., Two Chinese patients with Loeys-Dietz Syndrome due to TGFBR2 mutations, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Ho C.C., Liu A.P.Y., Lun K.S., Tam T., Chan K.K.L., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., 17p13.3 class I microduplication in a newborn with microcephaly, aortic stenosis and dysmorphic facial features, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Researcher : Mao H |
| List of Research Outputs |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Tu W., Mao H., Qin G., Zhang J. and Lau Y.L., Challenges and opportunities from the pandemic influenza A (H1N1), Chinese Journal of Pediatrics. 2010, 48: 561-563. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Researcher : Mao H |
| List of Research Outputs |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Tu W., Mao H., Qin G., Zhang J. and Lau Y.L., Challenges and opportunities from the pandemic influenza A (H1N1), Chinese Journal of Pediatrics. 2010, 48: 561-563. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Researcher : Mok SP |
| List of Research Outputs |
| Ha S.Y., Mok S.P., Lau Y.S., Rasalkar D.D., Cheuk D.K.L., Chiang A.K.S., Ho M.H.K. and Chan G.C.F., Intermediate term evaluation of a practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*, Hemoglobin 35(3):199-205. 2011. |
| Researcher : Ng KL |
| List of Research Outputs |
| Ho M.H.K., Wong L.M., Ling S.C., Lee K.P., Cheng W.W., Hui J., Lau D.C.Y., Ng K.L., Wong D., Kwok K.L. and Kwan E.Y.W., Identifying the service gaps in the management of severe systemic allergic reaction/anaphylaxis by Paediatrics Departments of the the Hospital Authority, Hong Kong Journal of Paediatrics (new series). 2010, 15: 186-197. |
| Researcher : Ning J |
| List of Research Outputs |
| Ning J., Xu X. and Chiang A.K.S., Analysis of CD4+ and CD8+ Epstein-Barr virus-specific polyfunctional T cell responses in Chinese long term carriers by a novel 9-colour flow cytometric assay., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Ning J., Xu X. and Chiang A.K.S., Characterization of CD4+ and CD8+ polyfunctional T cell responses to Epstein-Barr virus (EBV) latent and lytic proteins in Chinese long term carriers., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010. |
| Ning J., Xu X., Chan K.H. and Chiang A.K.S., Long-term carriers generate Epstein–Barr virus (EBV)-specific CD4+ and CD8+ polyfunctional T-cell responses which show immunodominance hierarchies of EBV proteins, Immunology. 2011, 134: 161-171. |
| Researcher : Ning J |
| List of Research Outputs |
| Ning J., Xu X. and Chiang A.K.S., Analysis of CD4+ and CD8+ Epstein-Barr virus-specific polyfunctional T cell responses in Chinese long term carriers by a novel 9-colour flow cytometric assay., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Ning J., Xu X. and Chiang A.K.S., Characterization of CD4+ and CD8+ polyfunctional T cell responses to Epstein-Barr virus (EBV) latent and lytic proteins in Chinese long term carriers., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010. |
| Ning J., Xu X., Chan K.H. and Chiang A.K.S., Long-term carriers generate Epstein–Barr virus (EBV)-specific CD4+ and CD8+ polyfunctional T-cell responses which show immunodominance hierarchies of EBV proteins, Immunology. 2011, 134: 161-171. |
| Researcher : Or CT |
| List of Research Outputs |
| Wang L., Yang L.H., Or C.T., Chen G., Zhou J., Li C.B. and Lau A.S.Y., Differential effects of Radix Paeoniae Rubra (Chishao) on cytokine and chemokine expression inducible by mycobacteria, Chin Med. 2011 Mar 30;6(1):14. 2011. |
| Wang L., Yang L.H., Or C.T., Li C.B. and Lau A.S.Y., Differential effects of radix paeoniae rubra on cytokine and chemokine expression inducible by mycobacterium., 9th Meetinhg of Consortium for Globalization of Chinese Medicine (CGCM), Hong Kong, August 23-25,. 2010. |
| Researcher : Qin G |
| List of Research Outputs |
| Tu W., Mao H., Qin G., Zhang J. and Lau Y.L., Challenges and opportunities from the pandemic influenza A (H1N1), Chinese Journal of Pediatrics. 2010, 48: 561-563. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Researcher : Tan TY |
| List of Research Outputs |
| Ho C.C., Liu A.P.Y., Lun K.S., Tam T., Chan K.K.L., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., 17p13.3 class I microduplication in a newborn with microcephaly, aortic stenosis and dysmorphic facial features, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Liu A.P.Y., Ho C.C., Yung T.C., Tam T., Chan K.K.L., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., Inverted duplication 18q12.1-q22, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Researcher : Tao KP |
| List of Research Outputs |
| Tao K.P., Ching Y.P. and Chan S.Y., TSPYL2 Is Important for G1 Checkpoint Maintenance upon DNA Damage, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2007. |
| Tao K.P., Fong S.W., Lu Z., Ching Y.P., Chan K.W. and Chan S.Y., TSPYL2 is important for G1 checkpoint maintenance upon DNA damage, PLoS One. 2011, 6(6): e21602. |
| Researcher : Teoh KT |
| List of Research Outputs |
| Teoh K.T., Siu Y.L., Chan W.L., Schlüter M.A., Liu C.J., Peiris J.S.M., Bruzzone R., Margolis B. and Nal-Rogier B.T.M., The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis., In: Asma Nusrat, Molecular Biology of the Cell. 2010, 21: 3838-3852. |
| Researcher : Ting JY |
| List of Research Outputs |
| Ting J.Y., Chan K.L., Wong M.S.C., Chim S. and Wong K.Y., Gastric Pneumatosis in a Premature Neonate, Americal Journal of Perinatol Respiratory. 2011, 1: 11-14. |
| Ting J.Y., Chan S.Y., Lung D.C., Ho A.C.C., Chiang A.K.S., Ha S.Y., Tsoi N.S. and Chan G.C.F., Intra-abdominal Rhizopus microsporus Infection Successfully Treated by Combined Aggressive Surgical, Antifungal, and Iron Chelating Therapy, Journal of Pediatric Hematology Oncology. 2010, 32(6): e238-e240. |
| Researcher : Tsang AMC |
| List of Research Outputs |
| Chow C.B., Ip P., Lee S.L., Tsang A.M.C., Chiu I., Wong W.H.S. and Lau Y.L., Policy brief: Children left unattended at home in Hong Kong , LC paper No. CB(2)1040/10-11(04), Welfare Services Panel, Legislative Council, Hong Kong, 17 Feb 2011. 2011. |
| Ip P., Chow C.B., Lee S.L., Tsang A.M.C., Chiu I.W.S., Wong W.H.S. and Lau Y.L., The need of policies and legislative changes for tobacco control in Hong Kong - Letter of recommendations to Hong Kong Legislative Council, LC paper No. No. CB(1)1768/10-11(07), Legislative Council, Hong Kong, 2 April 2011. , 2011. |
| Ip P., Chan E.K.L., Chow C.B., Wong W., Tsang A.M.C., Lee S.L. and Lau Y.L., Upsurging of child maltreatment admissions in Chinese by using ICD codes for maltreatment syndrome: A different experience in the East (Correspondence Letter) , Archives of Disease in Childhood (E publication 27 July 2010) . 2010. |
| Researcher : Tsao BP |
| List of Research Outputs |
| Luo X., Yang W., Ye D.Q., Cui H., Zhang Y., Hirankarn N., Qian X., Tang Y., Lau Y.L., de Vries N., Tak P.P., Tsao B.P. and Shen N., A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus, PLos Genetic. 2011, 7(6): e1002128. |
| Researcher : Tse KC |
| List of Research Outputs |
| Wong S.N., Tse K.C., Lee K.P., Yuen S.F., Leung L.C., Pau B.C., Chan W.K., Lee K.W., Cheung H.M., Chim S. and Yip C.M., Evaluating different imaging strategies in children after first febrile urinary tract infection, Pediatric Nephrology. 2010, 25(10): 2083-2091. |
| Researcher : Tsoi NS |
| List of Research Outputs |
| Ting J.Y., Chan S.Y., Lung D.C., Ho A.C.C., Chiang A.K.S., Ha S.Y., Tsoi N.S. and Chan G.C.F., Intra-abdominal Rhizopus microsporus Infection Successfully Treated by Combined Aggressive Surgical, Antifungal, and Iron Chelating Therapy, Journal of Pediatric Hematology Oncology. 2010, 32(6): e238-e240. |
| Researcher : Tu W |
| Project Title: | Humanized mouse as a model to study the antiviral activity of human gammadelta-T cells against human and avian influenza A viruses in vivo |
| Investigator(s): | Tu W, Lau YL, Peiris JSM, Law HKW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 08/2007 |
| Project Title: | The Role of Natural Killer Cells in the Pathogenesis of Avian Influenza Virus Infection |
| Investigator(s): | Tu W, Cheung CY, Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2009 |
| Completion Date: | 12/2010 |
| Project Title: | 98th Annual Meeting of the American Association of Immunologists (Immunology 2011) Effective control of influenza A virus infection by boosting gammadelta-T-cell immunity with pamidronate |
| Investigator(s): | Tu W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Grants for Teaching Staff |
| Start Date: | 05/2011 |
| Completion Date: | 05/2011 |
| List of Research Outputs |
| Liu Y., Tu W. and Lau Y.L., Dendritic cell function and T cell responses to influenza viruses in patients with X-Linked agammaglobulinemia, iImmunology 2011. |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Tu W., Anti-influenza immunity, In: Sichuan Association of Pediatrics, Sichuan Annual Pediatric Scientific Meeting. Chengdu, China, 2010. |
| Tu W., Mao H., Qin G., Zhang J. and Lau Y.L., Challenges and opportunities from the pandemic influenza A (H1N1), Chinese Journal of Pediatrics. 2010, 48: 561-563. |
| Tu W., Challenges and opportunities from the pandemic influenza A virus, 15th National Pediatric Congress, 25 September 2010, Chengdu, PR China. 2010. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Tu W., Host immune responses to respiratory viruses, International Forum on Respiratory Diseases 2010, 18-20 November 2010, Chongqing. 2010. |
| Tu W., Immune defense mechanisms against human and avian influenza viruses, 9th National Conference for Pediatric Infectious Diseases, 10-12 April 2011, Yangzhou, PR China. 2011. |
| Tu W., Immunopathogenesis of the Hang, Foot, and Mouth Diseases, 15th National Pediatric Congress, 25 September 2010, Chengdu, PR China. 2010. |
| Tu W., Innate and adaptive immune responses to influenza viruses, China-Australia Phenomics Symposium, 22-24 March 2011, The John Curtin School of Medical Research, The Australia National University, Canberra, Australia. 2011. |
| Tu W., Innate immune evasion and therapeutic strategies of influenza viruses, The Fourth International Symposium on Infection and Immunity. Chinese Acedemy of Sciences. Dunhuang, China, 2010. |
| Tu W., Pamidronate Boosts Gammadelta-T-Cell Immunity and Controls Influenza A Infection: A Novel Therapeutic Option for Influenza, Keystone Symposia Meeting on "Pathogenesis of Influeza: Host-Virus Interactions, 23-28 May 2011, Hong Kong. 2011. |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Wang Z., Luo H., Tu W., Yang H., Wong W.H.S., Wong W.T., Yung K.F., Zhou N., Zhang J., Li X., Wang Z., Guo W., Mu D., Li F., Mao M. and Lau Y.L., Melamine-tainted milk products associated urinary stones in children, Pediatrics International. 2010, doi: 10.1111/j. |
| Zheng J., Liu Y., Tu W. and Lau Y.L., Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway, Eur J Immunol. 2011 Jan;41(1):128-39.. 2011. |
| Researcher : Wang L |
| List of Research Outputs |
| Wang L., Yang L.H., Or C.T., Li C.B. and Lau A.S.Y., Differential effects of radix paeoniae rubra on cytokine and chemokine expression inducible by mycobacterium., 9th Meetinhg of Consortium for Globalization of Chinese Medicine (CGCM), Hong Kong, August 23-25,. 2010. |
| Researcher : Wong HT |
| List of Research Outputs |
| Wong K.K., Li Q., Wong H.T., Tsang K.H., Lai S.K., McAlonan G.M., Chan Y.S. and Chan S.Y., TSPYL2 regulates CREB-Dependent Gene Expression, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2079. |
| Researcher : Wong KK |
| List of Research Outputs |
| Wong K.K., Li Q., Wong H.T., Tsang K.H., Lai S.K., McAlonan G.M., Chan Y.S. and Chan S.Y., TSPYL2 regulates CREB-Dependent Gene Expression, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2079. |
| Wong K.K., Li Q., McAlonan G.M. and Chan S.Y., The role of TSPYL2 in learning and memory, 15th Research Postgraduate Symposium 2010 (December 1-2, 2010). 2010. |
| Researcher : Wong KK |
| List of Research Outputs |
| Wong K.K., Li Q., Wong H.T., Tsang K.H., Lai S.K., McAlonan G.M., Chan Y.S. and Chan S.Y., TSPYL2 regulates CREB-Dependent Gene Expression, 44th Annual Meeting of the Japanese Society of Developmental Biologists, Japan, 18-21 May 2011. P2079. |
| Wong K.K., Li Q., McAlonan G.M. and Chan S.Y., The role of TSPYL2 in learning and memory, 15th Research Postgraduate Symposium 2010 (December 1-2, 2010). 2010. |
| Researcher : Wong KT |
| List of Research Outputs |
| Chung B.H.Y., Chan S.Y., Chow P.C., Wong K.T., Lun K.S., Chau A.K.T. and Lau Y.L., Two Chinese patients with Loeys-Dietz Syndrome due to TGFBR2 mutations, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Researcher : Wong KY |
| List of Research Outputs |
| Ting J.Y., Chan K.L., Wong M.S.C., Chim S. and Wong K.Y., Gastric Pneumatosis in a Premature Neonate, Americal Journal of Perinatol Respiratory. 2011, 1: 11-14. |
| Researcher : Wong LM |
| List of Research Outputs |
| Ho M.H.K., Wong L.M., Ling S.C., Lee K.P., Cheng W.W., Hui J., Lau D.C.Y., Ng K.L., Wong D., Kwok K.L. and Kwan E.Y.W., Identifying the service gaps in the management of severe systemic allergic reaction/anaphylaxis by Paediatrics Departments of the the Hospital Authority, Hong Kong Journal of Paediatrics (new series). 2010, 15: 186-197. |
| Researcher : Wong MSC |
| List of Research Outputs |
| Ting J.Y., Chan K.L., Wong M.S.C., Chim S. and Wong K.Y., Gastric Pneumatosis in a Premature Neonate, Americal Journal of Perinatol Respiratory. 2011, 1: 11-14. |
| Researcher : Wong PTY |
| List of Research Outputs |
| Wong V.C.N. and Wong P.T.Y., Pilot Study for Subgroup Classification for Autism Spectrum Disorder Based on Dysmorphology and Physical Measurements in Chinese Paediatrics and Adolescent Population, 15th Research Postgraduate Symposium, Hong Kong, 1-2 Dec 2010. |
| Researcher : Wong SJ |
| List of Research Outputs |
| Cheung Y.F., Hong W., Chan G.C.F., Wong S.J. and Ha S.Y., Left ventricular myocaridal deformation and mechanical dyssynchrony in children with normal ventricular shortening fraction after anthracycline therapy, Heart. 2010, 96: 1137-1141. |
| Cheung Y.F., Liang X., Chan G.C.F., Wong S.J. and Ha S.Y., Myocardial iron load in patients with beta-thalassaemia major is associated with global left ventricular mechanical dyssynchrony (Abstract: Circulation 2010;122:A12192), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Koh C., Hong W., Wong S.J. and Cheung Y.F., Systolic-diastolic coupling of myocardial deformation of the left ventricle in children with left ventricular noncompaction, Heart Vessels. 2010, 25: 493-499. |
| Lai C.T.M., Chan K.W., Wong S.J., Chow P.C. and Cheung Y.F., Circulating levels of biomarkers of collagen synthesis correlate with left ventricular mechanical dyssynchrony in adolescents after repair of tetralogy of fallot (Abstract: Circulation 2010; 122:A12164), American Heart Association Scientific Sessions, Chicago, 13-17 November 2010. |
| Li S., Wong S.J. and Cheung Y.F., Left ventricular eccentricity impairs three-dimensional systolic radial strain and torsion in patients after repair of tetralogy of fallot: a three-dimensional speckle tracking analysis (Abstract: Circulation 2010; 122:A10455), American Heart Association Scientific Sessions 2010, Chicago, 13-17 November 2010. |
| Researcher : Wong SN |
| List of Research Outputs |
| Wong S.N., Tse K.C., Lee K.P., Yuen S.F., Leung L.C., Pau B.C., Chan W.K., Lee K.W., Cheung H.M., Chim S. and Yip C.M., Evaluating different imaging strategies in children after first febrile urinary tract infection, Pediatric Nephrology. 2010, 25(10): 2083-2091. |
| Researcher : Wong VCN |
| Project Title: | Rett Syndrome :Systematic screening of MECP2 in children with autistic traits and or unexplained mental retardation/ encephalopathy to define the spectrum of Rett Syndrome phenotypes resulting from mutations in MECP2 |
| Investigator(s): | Wong VCN |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2006 |
| Project Title: | Single-blinded, randomized, and placebo-controlled trial in FMR1 KO and WT mice |
| Investigator(s): | Wong VCN |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Chan A.S., Han Y.M.Y., Leung W.W.M., Leung C.S.Y., Wong V.C.N. and Cheung M.C., Abnormalities in the anterior cingulate cortex associated with attentional and inhibitory control deficits: A neurophysiological study on children with autism spectrum disorders, Research in Autism Spectrum Disorders. 2011, 5(1): 254-266. |
| Chan S.H.S., Wong V.C.N., Fung C.W., Dale R.C. and Vincent A., Anti-NMDA Receptor Encephalitis With Atypical Brain Changes on MRI, Pediatric Neurology. 2010, 43(4): 274-278. |
| Fung C.W. and Wong V.C.N., Clinical profile of 13 children with severe myoclonic epilepsy of infancy in Hong Kong., 8th Asian & Oceanian Epilepsy Congress, Melbourne, Australia, 21-24 October. 2010. |
| Liu Y., Zou L.P., Du J.B. and Wong V.C.N., Electro-acupuncture protectsagainst hypoxic-ischemic brain-damaged immature rat via hydrogen sulfide as a possible mediator, Neuroscience Letters. 2010, 485(1): 74-78. |
| Rose L. and Wong V.C.N., Possible effect of acupuncture in autism spectrum disorder. , Focus on Alternative and Complementary Therapies, 2011 Mar vol 16, Iss 1, p46-48. 2011. |
| Wong V.C.N., Cheuk D.K.L., Lee S. and Chu V.L.Y., Acupuncture for acute management and rehabilitation of traumatic brain injury. , Cochrane Database of Systematic Reviews 2011, Issue 5. Art. No.: CD007700. DOI: 10.1002/14651858.CD007700.pub2. . 2011. |
| Wong V.C.N. and Chu V.L.Y., Alternative therapy - TCM therapies. , In: JH Stone, M Blouin, editors., International Encyclopedia of Rehabilitation. Available online: http://cirrie.buffalo.edu/encyclopedia/en/article/325/. 2011. |
| Wong V.C.N., Author's reply: Acupuncture for children with autism spectrum disorder. , Focus on Alternative and Complementary Therapies, 16(2). 2011. |
| Wong V.C.N., Caring for our Children & Adolescents: Understanding Autism and the Harm of Drug Abuse - Diagnosis and Management of Autism , Explore the World of Medicine – Public Lecture Series 2010, Hong Kong, 11 Sep 2010. |
| Wong V.C.N., Editorial Board Member (since 2010), BMC Medicine. 2010. |
| Wong V.C.N., Editorial Board of Case Reports in Pediatrics (editorial board). 2011. |
| Wong V.C.N. and Wong C.L., Epilepsy and traditional Chinese medicine (Acupuncture & herbal medicine), Current Topics in Pediatric Epilepsy, 2010; 283-294. ISBN: 978-81-7895-471-4 . 2010. |
| Wong V.C.N., Global Developmental Delay (GDD) - A Delay in Development of terminology in the Global World (Editorial Paper), Developmental Medicine & Child Neurology. 2011. |
| Wong V.C.N., Honorary Editorial Board, Pediatric Health, Medicine and Therapeutics. 2010. |
| Wong V.C.N., Medical Hypotheses (reviewer). 2011. |
| Wong V.C.N. and Wong P.T.Y., Pilot Study for Subgroup Classification for Autism Spectrum Disorder Based on Dysmorphology and Physical Measurements in Chinese Paediatrics and Adolescent Population, 15th Research Postgraduate Symposium, Hong Kong, 1-2 Dec 2010. |
| Wong V.C.N., Prevalence of Autism Spectrum Disorders, culture, and ethnicity, Social Psychiatry and Psychiatric Epidemiology (Since 2010), Reviewer. 2010. |
| Wong V.C.N., Chen W. and Liu W.L., Randomized Controlled Trial of Electro-Acupuncture for Autism Spectrum Disorder, Alternative Medicine Review. 2010, 15(2): 136-146. |
| Wong V.C.N., Reviewer, International Journal of Disability, Development and Education (Since 2010). 2010. |
| Wong V.C.N., Reviewer, NeuroImage (Since 2010). 2010. |
| Wong V.C.N., Screening for Autism, ILAE Infantile Seizure Guidelines Task Force , San Antonio, US,13 Dec 2010. 2010. |
| Wong V.C.N., Social Psychiatry and Psychiatric Epidemiology (review). 2010. |
| Wong V.C.N. and Fung C.W., Spectrum of mitochondrial diseases in a tertiary referral centre in Hong Kong (poster), Hospital Authority Convention 2011, Hong Kong. 2011. |
| Wong V.C.N. and Chung B.H.Y., Value of clinical assessment in the diagnostic evaluation of Global Developmental Delay (GDD) using a Likelihood Ratio Model, Brain & Development. 2011, 33: 548-557. |
| Wu Y., Jin Z., Li K., Lu Z.L., Wong V.C.N., Han T.L., Zheng H., Caspi O., Liu G., Zeng Y.W. and Zou L.P., Functional Magnetic Resonance Imaging Activation of the Brain in Children: Real Acupoint Versus Sham Acupoint, Journal of Child Neurology. 2010, 25(7): 849-855. |
| Yeung W.L., Wong V.C.N., Chan K.Y., Hui J., Fung C.W., Yau F.T., Ko C.H., Lam C.W., Mak C.M., Siu S. and Low L.C.K., Expanding Phenotype and Clinical Analysis of Tyrosine Hydroxylase Deficiency, J Child Neurol 2011 26(2): 179-187. 2011. |
| Yung A.W.Y. and Wong V.C.N., Clinical outcome and long term prognosis of childhood epilepsy, 8th Asian & Oceanian Epilepsy Congress, Melbourne, Australia, 21-24 October. 2010. |
| Zhang C., Wong V.C.N., Ng P.W., Lui C.H., Sin N.C., Wong K.S., Baum L. and Kwan P., Failure to detect association between polymorphisms of the sodium channel gene SCN1A and febrile seizures in Chinese patients with epilepsy. , Epilepsia. . 2010, 51(9): 1878-1881. |
| Researcher : Wong WHS |
| List of Research Outputs |
| Cheung E.W.Y., Wong W.H.S. and Cheung Y.F., Meta-Analysis of Pulmonary Valve Replacement After Operative Repair of Tetralogy of Fallot, American Journal of Cardiology. 2010, 106: 552-557. |
| Chiu S.S.S., Chan K.H., Wong W.H.S., Chan L.Y. and Peiris J.S.M., Age-matched comparison of children hospitalized for 2009 pandemic H1N1 influenza with those hospitalized for seasonal H1N1 and H3N2, PLoS ONE. 2011, 6 (7): e21837. |
| Chiu S.S.S., Chan K.H., Chen H., Young B.W., Lim W., Wong W.H.S. and Peiris J.S.M., Virologically Confirmed Population-Based Burden of Hospitalization Caused by Respiratory Syncytial Virus, Adenovirus, and Parainfluenza Viruses in Children in Hong Kong, The Pediatric Infectious Disease Journal. 2010, 29: 000-000. |
| Chiu S.S.S., Chan K.H., Chen H., Young B.W.Y., Lim W., Wong W.H.S. and Peiris J.S.M., Virologically confirmed population-based burden of hospitalization caused by respiratory syncytial virus, adenovirus, and parainfluenza viruses in children in Hong Kong, The Pediatric Infectious Disease Journal [Epub ahead]. 2010, 29(12). |
| Chow C.B., Ip P., Lee S.L., Tsang A.M.C., Chiu I., Wong W.H.S. and Lau Y.L., Policy brief: Children left unattended at home in Hong Kong , LC paper No. CB(2)1040/10-11(04), Welfare Services Panel, Legislative Council, Hong Kong, 17 Feb 2011. 2011. |
| Ip P., Chow C.B., Lee S.L., Tsang A.M.C., Chiu I.W.S., Wong W.H.S. and Lau Y.L., The need of policies and legislative changes for tobacco control in Hong Kong - Letter of recommendations to Hong Kong Legislative Council, LC paper No. No. CB(1)1768/10-11(07), Legislative Council, Hong Kong, 2 April 2011. , 2011. |
| Lee S.L., Chiu S.S.S., Peiris J.S.M., Chan K.H., Wong W.H.S. and Lau Y.L., Is respiratory viral infection really an important trigger of asthma exacerbations in children?, Eur J Pediatr [Epub ahead]. 2011. |
| Wang Z., Luo H., Tu W., Yang H., Wong W.H.S., Wong W.T., Yung K.F., Zhou N., Zhang J., Li X., Wang Z., Guo W., Mu D., Li F., Mao M. and Lau Y.L., Melamine-tainted milk products associated urinary stones in children, Pediatrics International. 2010, doi: 10.1111/j. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Yang L., Chiu S.S.S., Chan K.P., Chan K.H., Wong W.H.S., Peiris J.S.M. and Wong C.M., Validation of statistical models for estimating hospitalization associated with influenza and other respiratory viruses, PLoS One. 2011, 6(3): e17882. |
| Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234. |
| Researcher : Xiang Z |
| List of Research Outputs |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Researcher : Xu X |
| List of Research Outputs |
| Ning J., Xu X. and Chiang A.K.S., Analysis of CD4+ and CD8+ Epstein-Barr virus-specific polyfunctional T cell responses in Chinese long term carriers by a novel 9-colour flow cytometric assay., The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus & Associated Diseases, University of Birmingham, UK, September 4-7, 2010. |
| Ning J., Xu X. and Chiang A.K.S., Characterization of CD4+ and CD8+ polyfunctional T cell responses to Epstein-Barr virus (EBV) latent and lytic proteins in Chinese long term carriers., 15th Research Postgraduate Symposium, LKS Faculty of Medicine, Hong Kong, December 1-2, 2010. |
| Ning J., Xu X., Chan K.H. and Chiang A.K.S., Long-term carriers generate Epstein–Barr virus (EBV)-specific CD4+ and CD8+ polyfunctional T-cell responses which show immunodominance hierarchies of EBV proteins, Immunology. 2011, 134: 161-171. |
| Researcher : Yang J |
| List of Research Outputs |
| Li R., Yang W., Yang J. and Lau Y.L., Association of CD247 with systemic lupus erythematosus in Asian Populations: A genome wide association study , Lupus. . 2011. |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Yang J., Yang W. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, American society of human genetics, 2010 . 2010. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Yang W., Li R., Yang J., Ye D.Q. and Lau Y.L., Genome-Wide Assocation Studies in Hong Kong identified Novel Susceptibility Genes for Systemic Lupus Erythematosus, American Society of Human Genetics, 2010. |
| Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234. |
| Researcher : Yang LH |
| List of Research Outputs |
| Lau A.S.Y. and Yang L.H., USA Patent Application #61/369,428: Uses of Cim-1 and Related Compounds for Treating Inflammation and Modulating Immune Responses. , Type: Provisional, Priority date for IP: 7/30/2010. (Assignee/owner: HKU). 2010. |
| Wang L., Yang L.H., Or C.T., Chen G., Zhou J., Li C.B. and Lau A.S.Y., Differential effects of Radix Paeoniae Rubra (Chishao) on cytokine and chemokine expression inducible by mycobacteria, Chin Med. 2011 Mar 30;6(1):14. 2011. |
| Wang L., Yang L.H., Or C.T., Li C.B. and Lau A.S.Y., Differential effects of radix paeoniae rubra on cytokine and chemokine expression inducible by mycobacterium., 9th Meetinhg of Consortium for Globalization of Chinese Medicine (CGCM), Hong Kong, August 23-25,. 2010. |
| Researcher : Yang M |
| Project Title: | Protective effect of thrombopoietin on iron-induced cardiomyopathy |
| Investigator(s): | Yang M |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 07/2007 |
| Project Title: | The effect of melatonin in the treatment of thrombocytopenia |
| Investigator(s): | Yang M |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme |
| Start Date: | 01/2008 |
| Project Title: | The protective effects of thrombopoietin and amlodipine on iron overload-induced human mesenchymal stem cell damage: its impact on iron overload related osteopenia & osteoporosis |
| Investigator(s): | Yang M, Chan GCF, Cheung YF, Liu C |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 01/2009 |
| List of Research Outputs |
| Ye J.Y., Chan G.C.F. and Yang M., Serotonin enhances megakaryopoiesis and proplatelet formation and stimulates TPO released from mesenchymal stromal cells (oral presentation)., 15th Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, Dec 1 & 2, 2010. |
| Researcher : Yang W |
| Project Title: | Association of Gene Copy Number Variations (CNV) in the FCGR locus with Systemic Lupus Erythematosus (SLE) |
| Investigator(s): | Yang W, Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2008 |
| Completion Date: | 07/2010 |
| Project Title: | Genetic variations in Jak2 gene and their roles in Systemic Lupus Erythematosus (SLE) susceptibility in different populations |
| Investigator(s): | Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2009 |
| Completion Date: | 11/2010 |
| Project Title: | Mapping Susceptibility Genes for Systemic Lupus Erythematosus (SLE) through a Genome-Wide Association Study |
| Investigator(s): | Yang W, Lau YL, Sham PC |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2009 |
| Project Title: | Non-HLA susceptibility genes associated with systemic lupus erythematosus in the HLA locus - A GWAS follow-up study |
| Investigator(s): | Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2010 |
| Completion Date: | 05/2011 |
| Project Title: | Functional characterization of a genetic variant we recently found to be associated with SLE in Asians |
| Investigator(s): | Yang W, Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2011 |
| List of Research Outputs |
| Li R., Yang W., Yang J. and Lau Y.L., Association of CD247 with systemic lupus erythematosus in Asian Populations: A genome wide association study , Lupus. . 2011. |
| Lin P., Mao F., Liu Q., Yang W., Shao C., Yan C. and Gong Y., A novel deletion mutation in GJB1 causes X-linked Charcot-Marie-Tooth disease in a Han Chinese family, Muscle & Nerve. 2010, 42(6): 922-926. |
| Luo X., Yang W., Ye D.Q., Cui H., Zhang Y., Hirankarn N., Qian X., Tang Y., Lau Y.L., de Vries N., Tak P.P., Tsao B.P. and Shen N., A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus, PLos Genetic. 2011, 7(6): e1002128. |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Niederer H.A., Willcocks L.C., Rayner T.F., Yang W., Lau Y.L., Williams T.N., Scott J.A.G., Urban B.C., Peshu N., Dunstan S.J., Hien T.T., Phu N.H., Padyukov L., Gunnarsson I., Svenungsson E., Savage C.O., Watts R.A., Lyons P.A., Clayton D.G. and Smith K.G.C., Copy number, linkage disequilibrium and disease association in the FCGR locus, Human Molecular Genetics. 2010, 19(6): 3282-3294. |
| Shen N., Fu Q., Deng Y., Qian X., Zhao J., Kaufman K.M., Wu Y.L., Yu C.Y., Tang Y., Chen J.Y., Yang W., Wong M., Kawasaki A., Tsuchiya N., Sumida T., Kawaguchi Y., Howes H.S., Mok T.M.Y., Bang S.Y., Liu F.L., Chang D.M., Takasaki Y., Hashimoto H., Harley J.B., Guthridge J.M., Grossman J.M., Cantor R.M., Song Y.W., Bae S.C., Chen S., Hahn B.H., Lau Y.L. and Tsao B.P., Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus, Proceeding of the National Academy of Sciences USA. 2010, 2010: 107(36). |
| Yang J., Yang W. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, American society of human genetics, 2010 . 2010. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Yang W., Li R., Yang J., Ye D.Q. and Lau Y.L., Genome-Wide Assocation Studies in Hong Kong identified Novel Susceptibility Genes for Systemic Lupus Erythematosus, American Society of Human Genetics, 2010. |
| Yang W., Identification of compound heterozygous mutations in an early onset Crohn's disease patient using whole exome sequencing technology, Asia Pacific Conference in Medical Genetics, Hong Kong, 4 November 2010. 2010. |
| Yang W., Mendelian diseases, complex diseases and those in between—and their study approaches, Frontiers in Biomedical Research HKU2010. 2010. |
| Yu F., Chen M.H., Kuo L., Huang P. and Yang W., Bayesian hierarchical modeling and selection of differentially expressed genes for the EST data, Biometrics. 2011, 67(1): 142-150. |
| Zhang L., Yang W., Ying D., Cherny S.S., Hildebrandt F., Sham P.C. and Lau Y.L., Homozygosity Mapping on a Single Patient-Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data, Human Mutation. 2011, 32 (3): 345-353. |
| Zhang Y., Yang W., Mok C.C., Chan T.M., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Yang J., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., Two missense variants in UHRF1BP1 are indpendently associated with systemic lupus erythematosus in Hong Kong Chinese, Genes and Immunity. 2011, 12(3): 231-234. |
| Researcher : Yau FT |
| List of Research Outputs |
| Yeung W.L., Wong V.C.N., Chan K.Y., Hui J., Fung C.W., Yau F.T., Ko C.H., Lam C.W., Mak C.M., Siu S. and Low L.C.K., Expanding Phenotype and Clinical Analysis of Tyrosine Hydroxylase Deficiency, J Child Neurol 2011 26(2): 179-187. 2011. |
| Researcher : Yeung WL |
| List of Research Outputs |
| Yeung W.L., Wong V.C.N., Chan K.Y., Hui J., Fung C.W., Yau F.T., Ko C.H., Lam C.W., Mak C.M., Siu S. and Low L.C.K., Expanding Phenotype and Clinical Analysis of Tyrosine Hydroxylase Deficiency, J Child Neurol 2011 26(2): 179-187. 2011. |
| Researcher : Yick LW |
| Project Title: | Defining the roles of epidermal growth factor (EGF) in the regulation of chondrocyte differentiation and endochondral bone formation |
| Investigator(s): | Yick LW, Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Researcher : Yim HCH |
| List of Research Outputs |
| Li C.B., Au K.Y., Fang J.W., Yim H.C.H., Chow K.H., Ho P.L. and Lau A.S.Y., HIV-1 trans-activator protein dysregulates IFN-γ signaling and contributes to the suppression of autophagy induction., AIDS. 2011, 25(1): 15-25. |
| Li C.B., Yim H.C.H. and Lau A.S.Y., Role of HIV-1 Tat in AIDS pathogenesis: its effects on cytokine dysregulation and contributions to the pathogenesis of opportunistic infection., AIDS. 2010, 24(11): 1609-23. |
| Researcher : Ying D |
| List of Research Outputs |
| Zhang L., Yang W., Ying D., Cherny S.S., Hildebrandt F., Sham P.C. and Lau Y.L., Homozygosity Mapping on a Single Patient-Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data, Human Mutation. 2011, 32 (3): 345-353. |
| Researcher : Young BWY |
| List of Research Outputs |
| Chiu S.S.S., Chan K.H., Chen H., Young B.W.Y., Lim W., Wong W.H.S. and Peiris J.S.M., Virologically confirmed population-based burden of hospitalization caused by respiratory syncytial virus, adenovirus, and parainfluenza viruses in children in Hong Kong, The Pediatric Infectious Disease Journal [Epub ahead]. 2010, 29(12). |
| Researcher : Yung AWY |
| List of Research Outputs |
| Lai V., Mak H.K.F., Yung A.W.Y., Ho W.Y. and Hung K.N., Neuroimaging techniques in epilepsy, Hong Kong Medical Journal. 2010, 16(4): 292-298. |
| Yung A.W.Y. and Wong V.C.N., Clinical outcome and long term prognosis of childhood epilepsy, 8th Asian & Oceanian Epilepsy Congress, Melbourne, Australia, 21-24 October. 2010. |
| Researcher : Yung TC |
| List of Research Outputs |
| Liu A.P.Y., Ho C.C., Yung T.C., Tam T., Chan K.K.L., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., Inverted duplication 18q12.1-q22, Hong Kong Paediatric Society Annual Scientific Meeting, QEH, HK, 4-5 June 2011. |
| Researcher : Zeng S |
| List of Research Outputs |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Researcher : Zeng S |
| List of Research Outputs |
| Mao H., Yang W., Ho M.H.K., Yang J., Zeng S., Chong C.Y., Lee T.L., Tu W. and Lau Y.L., Exome sequencing identifies novel compound heterozygous mutations of interleukin-10 receptor A in Crohn’s disease of neonatal onset , HKSPIID 4th ASM and 5th AGM,2011. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Researcher : Zhang J |
| List of Research Outputs |
| Tu W., Mao H., Qin G., Zhang J. and Lau Y.L., Challenges and opportunities from the pandemic influenza A (H1N1), Chinese Journal of Pediatrics. 2010, 48: 561-563. |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Researcher : Zhang L |
| List of Research Outputs |
| Zhang L., Yang W., Ying D., Cherny S.S., Hildebrandt F., Sham P.C. and Lau Y.L., Homozygosity Mapping on a Single Patient-Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data, Human Mutation. 2011, 32 (3): 345-353. |
| Zhang L., Yang W. and Ying D., Homozygosity mapping on a single patient - identification of homozygous regions of recent common ancestry by using population data., Human Mutation. 2011, 32(3): 345-353. |
| Zhang L., Homozygosity mapping on a single patient - identification of homozygous regions of recent common ancestry by using population data., Human Mutation. 2011, 32(3): 345-353. |
| Researcher : Zhang L |
| List of Research Outputs |
| Zhang L., Yang W., Ying D., Cherny S.S., Hildebrandt F., Sham P.C. and Lau Y.L., Homozygosity Mapping on a Single Patient-Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data, Human Mutation. 2011, 32 (3): 345-353. |
| Zhang L., Yang W. and Ying D., Homozygosity mapping on a single patient - identification of homozygous regions of recent common ancestry by using population data., Human Mutation. 2011, 32(3): 345-353. |
| Zhang L., Homozygosity mapping on a single patient - identification of homozygous regions of recent common ancestry by using population data., Human Mutation. 2011, 32(3): 345-353. |
| Researcher : Zhang Y |
| List of Research Outputs |
| Yang J., Yang W., Hirankarn N., Ye D.Q., Zhang Y., Pan H.F., Mok C.C., Chan T.M., Wong R.W.S., Mok M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Baum L., Kwan P., Lee T.L., Ho M.H.K., Lee P.P.W., Wong W.H.S., Zeng S., Zhang J., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S. and Lau Y.L., ELF1 is associated with systemic lupus erythematosus in Asian populations, Human Molecular Genetics. 2011, 20(3): 601-607. |
| Researcher : Zheng J |
| List of Research Outputs |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Zheng J., Liu Y., Tu W. and Lau Y.L., Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway, Eur J Immunol. 2011 Jan;41(1):128-39.. 2011. |
| Researcher : Zheng J |
| List of Research Outputs |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Zheng J., Liu Y., Tu W. and Lau Y.L., Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway, Eur J Immunol. 2011 Jan;41(1):128-39.. 2011. |
| Researcher : Zheng J |
| List of Research Outputs |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-react against 2009 Pandemic H1N1 Influenza Virus., Journal of Virology. 2010, 84: 6527-35. |
| Tu W., Mao H., Zheng J., Liu Y., Chiu S.S.S., Qin G., Chan P.L., Lam K.T., Guan J., Zhang L., Guan Y., Yuen K.Y., Peiris J.S.M. and Lau Y.L., Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus, J Virol. 2010, 84(13): 6527-35. |
| Tu W., Zheng J., Liu Y., Sia S.F., Liu M., Qin G., Ng I.H.Y., Xiang Z., Lam K.T., Peiris J.S.M. and Lau Y.L., The aminobisphosphonate pamidronate controls influenza pathogenesis by expanding a gammadelta T cell population in humanized mice, Journal of Experimental Medicine. 2011. |
| Zheng J., Liu Y., Tu W. and Lau Y.L., Generation of human Th1-like regulatory CD4+ T cells by an intrinsic IFN-γ- and T-bet-dependent pathway, Eur J Immunol. 2011 Jan;41(1):128-39.. 2011. |