SCHOOL OF CHINESE MEDICINE



Researcher : Cai Y

Project Title:14th World Congress of Food Science and Technology Effects of phytochemicals on reduction of acrylamide in an asparagine/glucose model system
Investigator(s):Cai Y
Department:School of Biological Sciences
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2008


List of Research Outputs

Zhang Y., Sze C.W., Tong Y., Cai Y., Liu J., Lee C.K.F. and Leung G.P.H., Comparative Analysis of Caffeoylquinic Acids and Lignans in Roots and Seeds among Various Burdock (Arctium lappa) Genotypes with High Antioxidant Activity., In: Liu JY, Cai YZ, Wong RNS, Lee KF, Tang CY, Sze CW, Tong Y and Zhang YB*. , J Agri Food Chem. 2012 April, 60 (16): 4067–75. . 2012, 60: 4067–75.


Researcher : Chen J

Project Title:Molecular mechanisms of natural LDH-A inhibitors from Spatholobus suberectus inducing mitochondrial pathway apoptosis
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Travel Grants for NSFC/RGC JRS
Start Date:12/2009


Project Title:Mechanism exploration of increased intracellular level of ROS in inhibiting breast caner growth and metastasis caused by Spatholobus suberectus
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:01/2010
Completion Date:01/2012


Project Title:Regulation Role and Mechanisms of LDH-A on Angiogenesis and VEGF Expression in Cancer Cells
Investigator(s):Chen J, Guan X
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:The development of multimedia tearching and learning system in TCM -prescrption subject
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:07/2011


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:01/2012


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A (ITS/073/11FP)
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:the 9th European Congress on Menopause and Andropause ELLAGIC ACID ANTI-ANGIOGENESIS EFFECTS VIA VEGFR-2 SIGNALING PATHWAY IN BREAST CANCER
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:03/2012


Project Title:Inhibiting breast cancer metastasis through TGF-β1-Induced Epithelial-Mesenchymal Transition (EMT) by Isoliquiritigenin (ISL)
Investigator(s):Chen J, Guan X
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


List of Research Outputs

Chen J., Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer, 9th European congress menopause and Andropause. 2012.
Chen J., International Standard English Chinese Medicine Textbook Prescription, 2011.
Chen J., International Standard English Chinese Medicine Textbook Prescription, People's Health Publishing House China, 2011.
Chen J., Wang N. and Wang Z., Targeting tumor angiogenesis: insights from Chinese Medicine , OOTR. 2012.
Lee W.S., Xu M., Li Y., Gu Y., Chen J., Wong D., Fung P.C.W. and Shen J., Free cholesterol accumulation impairs antioxidant activities and aggravates apoptotic cell death in menadione-induced oxidative injury., Arch Biochem Biophys. . 2011, 514(1-2): 57-67.
Li Z.X., Yang D.P., Huang M.L., Hu X.J., Shen J., Zhao Z.M. and Chen J., Chrysomya megacephala (Fabricius) larvae: A new biodiesel resource. , Applied Energy. 2012, 94: 349-354.
Wang N., Wang Z., Mo S.L., Loo T.Y., Wang D.M., Luo H.B., Yang D.P., Chen L.Y., Shen J. and Chen J., Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer. , Breast Cancer Research and Treatment. 2012, 134(3):: 943-55.
Wang Z., Cheng Y., Wang N., Wang D.M., Li Y.W., Han F., Shen J., Yang D.P., Guan X. and Chen J., Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins., Cancer Biology & Therapy . 2012, 13(3): 138-147.
Wang Z., Wang N., Chen J. and Shen J., Emerging Glycolysis Targeting and Drug Discovery from ChineseMedicine in Cancer Therapy, Evidence-Based Complementary and Alternative Medicine. 2012, 2012: Article ID 873175.
Wang Z., Loo T.Y., Wang N., Wang D., YAng D. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By A Medicinal Herb: Sanguisorba officinalis L., Expert Opinion on Biological Therapy,. 2012.
Yang X., Huang B., Chen J., Huang S., Zheng H., Lun Z., Shen J. and Lu F., In vitro effects of aqueous extracts of Astragalus membranaceus and Scutellaria baicalensis GEORGI on Toxoplasma gondii, Parasitol Res . USA, 2012.


Researcher : Chen X

List of Research Outputs

Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.
Zhao H., Ren C.C., Chen X. and Shen J., From rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemia., Current Drug Targets . 2012, 13(2): 173-187.


Researcher : Cheng LY

List of Research Outputs

Sze C.W., Ip C.W., Ng T.B., Zhang Y., Zhang Z., Cheung H.P., Cheng L.Y. and Tong Y., Compatibility of multiple herbal components in Erxian Decoction, a Chinese medicinal formula, for treating osteoporosis, European Journal of Integrative Medicine. 2012, 4: 187-196.


Researcher : Cheung F

List of Research Outputs

Cheung F., Feng Y., Wang M.N., Yuen R.M.F., Tong Y. and Wong V.C.W., Effectiveness of Chinese herbal medicine in treating liver fibrosis: a systematic review and meta-analysis of randomized controlled trials., Chin Med, 2012, 7(1):5.
Feng Y., Wang M.N., Ye X., Li H., Cheung F. and Nagamatsu T., Hepatoprotective effect and its possible mechanism of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced chronic liver hepatotoxicity in rats, Journal of Ethnopharmacology, 2011, 138(3):683-90.
Feng Y.G., Wang M.N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies . 2011.
Feng Y.G., Wang N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies (pp332-362). 2011.
Wang X., Feng Y., Wang M.N., Cheung F. and Wong C.W., Recent Progress on Anti-Liver Fibrosis Candidates in Patents of Herbal Medicinal Products., Recent Pat Food Nutr Agric., 2012.


Researcher : Cheung HP

List of Research Outputs

Sze C.W., Ip C.W., Ng T.B., Zhang Y., Zhang Z., Cheung H.P., Cheng L.Y. and Tong Y., Compatibility of multiple herbal components in Erxian Decoction, a Chinese medicinal formula, for treating osteoporosis, European Journal of Integrative Medicine. 2012, 4: 187-196.
Sze C.W., Leigh A. and Cheung H.P., Novel Bioactive Protein isolated from Chinese Yam (Dioscorea opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome, Hong Kong Summit - Science Park. 2012.
Zhang Y., Sze C.W., Cheung H.P. and Ho K.L., Study on Anti-cancer Effect of 6-Hydroxydendroxine, A Chemical Component from Dendrobium nobile Lindl., on HT-29 Human Colorectal Cancer Cells. , In: Ho Ka-Lai, Cheung Ho-Pan, Stephen Sze Cho-Wing, Kalin Zhang Yanbo. , 18th Hong Kong International Cancer Congress to be held on 3 – 5 November, 2011. Cheung Kung Hai Conference Centre, Li Ka Shing Faculty of Medicine, The University of Hong Kong. Hong Kong.. 2011.


Researcher : Cheung HP

List of Research Outputs

Sze C.W., Ip C.W., Ng T.B., Zhang Y., Zhang Z., Cheung H.P., Cheng L.Y. and Tong Y., Compatibility of multiple herbal components in Erxian Decoction, a Chinese medicinal formula, for treating osteoporosis, European Journal of Integrative Medicine. 2012, 4: 187-196.
Sze C.W., Leigh A. and Cheung H.P., Novel Bioactive Protein isolated from Chinese Yam (Dioscorea opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome, Hong Kong Summit - Science Park. 2012.
Zhang Y., Sze C.W., Cheung H.P. and Ho K.L., Study on Anti-cancer Effect of 6-Hydroxydendroxine, A Chemical Component from Dendrobium nobile Lindl., on HT-29 Human Colorectal Cancer Cells. , In: Ho Ka-Lai, Cheung Ho-Pan, Stephen Sze Cho-Wing, Kalin Zhang Yanbo. , 18th Hong Kong International Cancer Congress to be held on 3 – 5 November, 2011. Cheung Kung Hai Conference Centre, Li Ka Shing Faculty of Medicine, The University of Hong Kong. Hong Kong.. 2011.


Researcher : Chow OY

List of Research Outputs

Feng Y., Wang M.N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on bear bile and coptis. Handbook with programme 19, 8th world congress of Chinese Medicine. 2011.


Researcher : Feng Y

Project Title:The role of autophagy and mitochondrial apoptosis in berberine induced hepatocellular caricinoma cell death and its underlying mechanism
Investigator(s):Feng Y, Tsao GSW
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:09/2009
Completion Date:08/2011


Project Title:The inhibitory action of berberine on hepatocellular carcinoma
Investigator(s):Feng Y, Man K, Tong Y, Tsao GSW
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:The anti-metastasis effect and its underlying mechanism of genipin derived from Chinese herbal Gardenia jasminoides in hepatocellular caricinoma cell and animal models
Investigator(s):Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012


List of Research Outputs

4. Hirasawa Y., Nishiyama T., Nagao T. and Feng Y., Involvement of protein kinase C in reduction of aggregated protein and phosphorylation of CREB in glomeruli, Exp Anim, 2012.
Cheung F., Feng Y., Wang M.N., Yuen R.M.F., Tong Y. and Wong V.C.W., Effectiveness of Chinese herbal medicine in treating liver fibrosis: a systematic review and meta-analysis of randomized controlled trials., Chin Med, 2012, 7(1):5.
Feng Y. and Wang F., 心理學與我——你的第一本心理學書, Beijing cheers books Co. Ltd. 2011.
Feng Y., Chinese medicine as a complementary and alternative prevention and treatment for cancer: from traditional perspective to scientific exploration, Japan Society of Oncology, 2012 Annual Meeting. 2012.
Feng Y., Wang M.N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on bear bile and coptis. Handbook with programme 19, 8th world congress of Chinese Medicine. 2011.
Feng Y., Chueng X.M., Wang N. and Shen J., Current Progress on Medicinal Plants and their Biological Properties in Contemporary China. Chapter in Recent Progress in Medicinal Plants, Ethnomedicine: Source & Mechanism-II. Studium Press LLC, USA. 2011, 28.
Feng Y., Discover anticancer candidates from Chinese medicines: from screening exploration to mechanism studies, 8th Hong Kong International Cancer Congress. 2011.
Feng Y., Editor, In: Feng Yibin (2011-2013), Journal of Bioequivalence & Bioavailability. Henderson NV 89074-7722, USA, OMICS Group Incorporation, 2011.
Feng Y., Editorial Board member from January 2010 to December 2011, In: Yeung Hin Win, Chinese Medicine. BioMed Central, 2012.
Feng Y., Editorial Board member from January 2010 to December 2011, In: Yeung Hin Win, Chinese Medicine. BioMed Central, 2012.
Feng Y. and Xu D.J., Feng’s case report in Chinese Medicine , 馮奕斌醫案選錄, Case report of Chinese Medicine in Hong Kong. 香港中醫醫案, 2012.
Feng Y., Wang M.N., Ye X., Li H., Cheung F. and Nagamatsu T., Hepatoprotective effect and its possible mechanism of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced chronic liver hepatotoxicity in rats, Journal of Ethnopharmacology, 2011, 138(3):683-90.
Feng Y., Hong Kong Chinese Medical Journal, In: 陈抗生, 邓春, 温桂荣, 赵中正, 冯奕斌, 吴俊来, 王如跃, 黄约爱,, Hong Kong Chinese Medical Journal. 香港中医杂志, Hong Kong, 香港中医杂志出版社, 2012.
Feng Y., Integrated therapy and Chinese medicine new therapy exploring for liver cancer treatment , 肝癌的中西醫合作治療和中醫藥治療的新探索, Public lecture for foundation of Chinese medicine special for cancer in School of Chinese Medicine, The University of Hong Kong. 2012.
Feng Y., Pharmacology of traditional Chinese medicine in internal medicine , 中醫內科常見中藥藥理學, Hong Kong arthritis & rheumatism foundation scientific committee “East meets West” series 2011: Traditional Chinese Medicines in Arthritis. 2011.
Feng Y.G., Wang M.N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies . 2011.
Feng Y.G., Wang N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies (pp332-362). 2011.
Lam S.S. and Feng Y., 香砂六君湯合葛根芩連湯治療大腸癌經驗探析, 香港中醫雜誌. 2011.
To C.S., Liew C., Wang X., Wang M.N. and Feng Y., Comparison of Components and Anti-Liver Cancer Activity in Vitro between Huanglian and Yunlian, Journal of Bioequivalence & Bioavailability, 2012.
Tong Y., Zhong L. and Feng Y., The Implementation of PBL in Chinese Medicine Program at The University of Hong Kong, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.
Wang D., Wong H.K., Zhang L., McAlonan G.M., Wang X.M., Sze C.W., Feng Y. and Zhang Z., Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemia, Progress in Neuro-Psychopharmacology & Biological Psychiatry . 2012, in press: n/a.
Wang F. and Feng Y., Choices and Changes--- the psychology of personal growth and interpersonal relationships, 心理學與我——你的第一本心理學書, Beijing cheers books Co. Ltd, 2011.
Wang M.N., Pan W., Zhu M., Zhanf M., Hao X., Laing G. and Feng Y., Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signaling in human hepatocellular carcinoma cells, British Journal of Pharmacology, 2011, 164: 731-742.
Wang M.N., Pan W., Zhu M., Zhanf M., Hao X., Lian G. and Feng Y., Fangchinoline is a potential anti-cancer drug by inducing autophagic cell death in heaptocellular carcinoma cells, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.
Wang N., Feng Y., Lau E.P., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W. and Tsao G.S.W., F-actin reorganization and inactivation of rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration., Integrate Cancer Therapy. 2011.
Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, Journal of cellular biochemistry. 2011.
Wang X., Feng Y., Wang M.N., Cheung F. and Wong C.W., Recent Progress on Anti-Liver Fibrosis Candidates in Patents of Herbal Medicinal Products., Recent Pat Food Nutr Agric., 2012.
Zhong L., Tong Y. and Feng Y., The implementation of PBL in Chinese Medicine Program at the University of Hong Kong, The 10th Meeting of Consortium for Globalization of Chinese Medicine. 2011, 189.
Zhu M., Wang M.N., Tsao G.S.W. and Feng Y., miR-21 and miR-23a were altered by Coptidis Rhizoma Aqueous Extract in Human Liver Cancer Cells, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.


Researcher : Fu S

List of Research Outputs

Li Y., Luo J., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y. and Shen J., Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway, PLoS One. 2011, 6(8): 22901.


Researcher : Gu Y

List of Research Outputs

Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.
Lee W.S., Xu M., Li Y., Gu Y., Chen J., Wong D., Fung P.C.W. and Shen J., Free cholesterol accumulation impairs antioxidant activities and aggravates apoptotic cell death in menadione-induced oxidative injury., Arch Biochem Biophys. . 2011, 514(1-2): 57-67.


Researcher : Hu KY

Project Title:Quality Assessment of Chinese Medicine Formula, Erxian Decoction, by high-performance liquid chromatography coupled with diode array detector
Investigator(s):Hu KY, Tong Y, Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:10/2008


Project Title:The 6th World Congress of Chinese Medicine 2009 The International Spread Characteristics of Traditional Chinese Medicine
Investigator(s):Hu KY
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2009




Researcher : Ip CW

List of Research Outputs

Sze C.W., Ip C.W., Ng T.B., Zhang Y., Zhang Z., Cheung H.P., Cheng L.Y. and Tong Y., Compatibility of multiple herbal components in Erxian Decoction, a Chinese medicinal formula, for treating osteoporosis, European Journal of Integrative Medicine. 2012, 4: 187-196.


Researcher : Jiang J

List of Research Outputs

Yang L.P., Xu W.C., Shen J., Li J. and Jiang J., Secondary Metabolites Of Genus Astragalus : Structure And Biological Activity Update, Chemistry & Biodiversity . 2012, doi: 10.1002/cbdv.201100444.


Researcher : Lam SS

List of Research Outputs

Lam S.S. and Feng Y., 香砂六君湯合葛根芩連湯治療大腸癌經驗探析, 香港中醫雜誌. 2011.


Researcher : Lee WS

List of Research Outputs

Lee W.S., Xu M., Li Y., Gu Y., Chen J., Wong D., Fung P.C.W. and Shen J., Free cholesterol accumulation impairs antioxidant activities and aggravates apoptotic cell death in menadione-induced oxidative injury., Arch Biochem Biophys. . 2011, 514(1-2): 57-67.


Researcher : Li L

Project Title:Mechanistic study of circadian rhythm of tryptophan hydroxylase and serotonergic receptors involved in acupuncture analgesia
Investigator(s):Li L, Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:02/2011
Completion Date:02/2012


Project Title:2012 台北國際中醫藥學術論壇 衝脈循行考(A Study of the Vital Channel’s Running Route)
Investigator(s):Li L
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:03/2012


List of Research Outputs

Li L., Lo K.C. and Yau T., A Rustic Opinion on the “Modernization of Traditional Chinese Medicine” , The 10th Meeting of The Consortium for Globalization of Chinese Medicine (CGCM) . Shanghai, China, 2011.
Li L. and Yau C.H., A Study of the Vital Channel’s Running Route, 衝脈循行考, Taipei Traditional Chinese Medicine International Forum 2012. 2012臺北國際中醫藥學術論壇, Taipei, Tanwan.
Li L., Acupuncture Methods of Epidemic Diseases in Lost Chapters of “The Yellow Emperor's Internal Classic” , 《素問遺篇》中的運氣針法, 2011 Chinese National Conference on Chronabiology . 2011全國時間生物醫學學術會議, 2011.
Li L., Acupuncture Summary of “The Yellow Emperor's Internal Classic” and “The Classic on Medical Problems”. 《內經》《難經》針灸輯要, Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2012, 775.
Li L., Yau T. and Yau C.H., Acupuncture and Needle-Stimulation, Differences in Concepts and Methods, Chinese Medicine. USA, Scientific Research Publishing Inc., 2012, 3(1): 13-19.
Li L., Yau T. and Yau C.H., Acupuncture and Needle-stimulation, Different Concepts and Different Methods , The 10th Meeting of The Consortium for Globalization of Chinese Medicine (CGCM). Shanghai, China, 2011.
Li L., Annotations of Classificatory Cases in Chinese Medicine. 歷代名醫醫案類釋, Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2012, 597.
Li L. and Yau C.H., Culture meaning in Names of “The Yellow Emperor's Internal Classic”, “The Plain Conversation” and “The Spiritual Pivot”, 《黃帝內經》、《素問》、《靈樞》諸書名的文化內涵, In: 中國中醫藥學會,廈門市中醫藥學會, Traditional Chinese Medicine Journal. 中醫藥通報, 中國廈門, 中醫藥通報雜誌社, 2011, 10(6): 45-48.
Li L. and Yau C.H., Discussion on the Principle of Five Shu Points from Characteristics of Shu Point Indications, 試論五輸穴的主治涵義, In: 中國中醫藥學會,廈門市中醫藥學會, Traditional Chinese Medicine Journal. 中醫藥通報, 中國廈門, 中醫藥通報雜誌社, 2012, 11(1): 37-38.
Li L., Emendations and Scholiumes on “Catechism of Acupuncture and Moxibustion”. 《針灸問對》校注, Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2011, 357.
Li L. and Yau C.H., The Time of Sui-Reinforcing and Ying-Reducing - Acupuncture Reinforcing and Reducing Methods in “Nine Needles and Twelve Yuan of The Spiritual Pivot”, 迎隨補瀉的時機——從《靈樞•九針十二原》看針刺補瀉, In: 中國中醫藥學會,廈門市中醫藥學會, Traditional Chinese Medicine Journal. 中醫藥通報, 中國廈門, 中醫藥通報雜誌社, 2011, 10(5): 36-37.
Li L., Traditional Qigong and Retrograde Practice, The 11th Shanghai International Qigong Conference. 2011.
Li L., Yau T. and Yau C.H., What is the Origin of Acupoint, In: Shanghai Research Institutel of Acupuncture and Moxibustion, Journal of Acupuncture and Tuina Science. Shanghai, China, Editoral Department of Shanghai Journal of Acupuncture and M, 2012, 10(2): 125-127.
Lo K.C. and Li L., Acupuncture on Time - Discussions on the Acupuncture-time Thought of “Yellow Emperor's Internal Classic”, 審時知機,按時鍼刺——試論《黃帝內經》中按時鍼刺的學術思想, Taipei Traditional Chinese Medicine International Forum 2012. 2012臺北國際中醫藥學術論壇, Taipei, Tanwan.
Lo K.C., Zhang W. and Li L., Clinical Study on Acupoints Application Treatment of the Three Dog Days Treating Nonacutebronchial Asthma – Randomized Double-blind Placebo Controlled Trial , 2011 Chinese National Conference on Chronabiology. Nanning, China, 2011.
Qiu T., Li L. and Zhang W., Advance in Clinical Study of Treating Rheumatoid Arthritis with Acupuncture and Moxibustion, 針灸治療類風濕性關節炎的臨床研究進展, In: 香港註冊中醫學會,中國中醫雜誌社, Hong Kong Chinese Medicine Journal. 香港中醫雜誌, 香港, 香港中醫雜誌出版部, 2011, 6(4): 74-78, 82.
Qiu T. and Li L., Contentions on “the Chinese edition of the WHO Standard Acupuncture Point Locations in the Western Pacific Region” , 對《世界衛生組織標準針灸經穴定位》中文譯本的商榷, Journal of Chinese Acupuncture & Moxibustion. 中國針灸, 北京, 中國針灸學會,中國中醫研究院針灸研究所, 2011, 31(9): 827-830.
Qiu T. and Li L., Discussion on the “Idea” of Wing-chun for Preventing Spinal Disorders, The 11th Shanghai International Qigong Conference. 2011.
Wang Y...X... and Li L., A Review of Clinical Rresearch on Acupuncture Treatment of Children with ADHD, 針灸治療小兒多動症的研究進展, In: 香港註冊中醫學會,中國中醫雜誌社, Hong Kong Chinese Medicine Journal. 香港中醫雜誌, 香港, 香港中醫雜誌出版部, 2012, 7(1): 91-94.
Wang Y.X. and Li L., The Study Progress of Acupuncture Treatment of Pediatric Autism, 針刺治療小兒自閉症的研究進展, In: 甘肅中醫學院,中華中醫藥學會, Journal of Pediatrics of Traditional Chinese Medicine. 中醫兒科雜誌, 中國蘭州, 《中醫兒科雜誌》編輯室, 2012, 8(2): 60-63.
Yau C.H. and Li L., The Notions for the Forming of Acupuncture Reinforcing-Reducing Methods, 針刺補瀉手法產生的理念, In: 香港註冊中醫學會,中國中醫雜誌社, Hong Kong Chinese Medicine Journal. 香港中醫雜誌, 香港, 香港中醫雜誌出版部, 2011, 6(4): 66-67.
Yau T. and Li L., Conception, Governor and Thoroughfare Vessels are One, The 10th Meeting of The Consortium for Globalization of Chinese Medicine (CGCM) . Shanghai, China, 2011.
Zhang W. and Li L., The Clinical Study of Tian Jiu Therapy on Treating Asthma, The 10th Meeting of The Consortium for Globalization of Chinese Medicine (CGCM) . Shanghai, China, 2011.


Researcher : Li TYJ

List of Research Outputs

Zhang Z., Ng R., Man M.S.C., Li T.Y.J., Wong W., Tan Q.R., Wong H.K., Chung K.F., Wong M.T., Tsang W.K.A., Yip K.C., Ziea E. and Wong V.C.W., Dense cranial electroacupuncture stimulation for major depressive disorder: a single-blind, randomized, controlled study, PloS ONE . 2012, 7: e29651.


Researcher : Li Y

List of Research Outputs

Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.
Lau W.M., Lee C.D., Li Y., Fung M.Y., Sang Y., Shen J., Chang R.C.C. and So K.F., Polysaccharides from wolfberry prevents corticosterone-induced inhibition of sexual behavior and increases neurogenesis, PLoS One. 2012, 7(4): e33374.
Lee W.S., Xu M., Li Y., Gu Y., Chen J., Wong D., Fung P.C.W. and Shen J., Free cholesterol accumulation impairs antioxidant activities and aggravates apoptotic cell death in menadione-induced oxidative injury., Arch Biochem Biophys. . 2011, 514(1-2): 57-67.
Li Y., Zhuang P.W., Shen B.R., Zhang Y.J. and Shen J., Baicalin promotes neuronal differentiation of neural stem/progenitor cells through modulating p-stat3 and bHLH family protein expression., Brain Research . 2012, 1429: 36-42.
Li Y., Luo J., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y. and Shen J., Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway, PLoS One. 2011, 6(8): 22901.


Researcher : Li Y

List of Research Outputs

Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.
Lau W.M., Lee C.D., Li Y., Fung M.Y., Sang Y., Shen J., Chang R.C.C. and So K.F., Polysaccharides from wolfberry prevents corticosterone-induced inhibition of sexual behavior and increases neurogenesis, PLoS One. 2012, 7(4): e33374.
Lee W.S., Xu M., Li Y., Gu Y., Chen J., Wong D., Fung P.C.W. and Shen J., Free cholesterol accumulation impairs antioxidant activities and aggravates apoptotic cell death in menadione-induced oxidative injury., Arch Biochem Biophys. . 2011, 514(1-2): 57-67.
Li Y., Zhuang P.W., Shen B.R., Zhang Y.J. and Shen J., Baicalin promotes neuronal differentiation of neural stem/progenitor cells through modulating p-stat3 and bHLH family protein expression., Brain Research . 2012, 1429: 36-42.
Li Y., Luo J., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y. and Shen J., Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway, PLoS One. 2011, 6(8): 22901.


Researcher : Lin X

List of Research Outputs

Lin X., Song J., Shaw P.C., Ng T.B., Sze C.W., Tong Y., Lee C.K.F. and Zhang Y., An Autoimmunized Mouse Model Recapitulates Key Features in the Pathogenesis of SjÖgren’s Syndrome, In: Lin X, Song JX, Shaw PC, Ng TB, Stephen Sze CW, Tong Y, Lee KF, Kalin Zhang YB., International Immunology. 2011 Oct, 23(10): 613-24.. 2011, 23: 613-24.
Zhang Y., Lin X., Song J., Shaw P.C., Ng T.B. and Wong R.N.S., Dendrobium officinale polysaccharides ameliorate the abnormality of aquaporin 5, pro-inflammatory cytokines and inhibit apoptosis in the experimental Sjögren's syndrome mice., In: Lin X, Song JX, Shaw PC, Ng TB, Ricky Wong NS, Stephen Sze CW, Tong Y, Lee KF, Zhang YB*., Int Immunopharmacol. 2011 Sep, 11(12): 2025-32.. 2011, 11: 2025-32.


Researcher : Liu C

Project Title:6th Annual Rocky Mountain Bioinformatics Conference CADEG, a Set of Software Tools for High Resolution Identification of Potential Chromosomal Abnormalities
Investigator(s):Liu C
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2008


List of Research Outputs

Deng R.X., Chan G.C.F., Shen J., Ye J.Y., Ma M., Chen J.L., Liu C., Dee C.M. and Yang M., Astragaloside IV enhanced haematopoiesis via the EGFR-MEK-EKR1/2 signalling pathway., Hong Kong Journal of Paediatrics. 2011;16:217 (Proceedings for Joint Annual Scientific Meeting 2011: The Hong Kong Paediatric Society and American Academy of Pediatrics in conjunction with Hong Kong Paediatric Nurses Association). 2011, 16: 217.


Researcher : Liu J

List of Research Outputs

Zhang Y., Sze C.W., Tong Y., Cai Y., Liu J., Lee C.K.F. and Leung G.P.H., Comparative Analysis of Caffeoylquinic Acids and Lignans in Roots and Seeds among Various Burdock (Arctium lappa) Genotypes with High Antioxidant Activity., In: Liu JY, Cai YZ, Wong RNS, Lee KF, Tang CY, Sze CW, Tong Y and Zhang YB*. , J Agri Food Chem. 2012 April, 60 (16): 4067–75. . 2012, 60: 4067–75.
Zhang Y., Tong Y., Sze C.W., Liu J., Ng T.B., Wong H. and Ye X.J., Review of research on Dendrobium, a prized folk medicine., In: Tzi Bun Ng, Jingyi Liu, Jack Ho Wong, Xiujuan Ye, Stephen Cho Wing Sze, Yao Tong, Kalin Yanbo Zhang*., Appl Microbiol Biotechnol. 2012, 93:1795–1803. . 2012, 93: 1795-1803.


Researcher : Liu KJ

List of Research Outputs

Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.


Researcher : Lo KC

List of Research Outputs

Li L., Lo K.C. and Yau T., A Rustic Opinion on the “Modernization of Traditional Chinese Medicine” , The 10th Meeting of The Consortium for Globalization of Chinese Medicine (CGCM) . Shanghai, China, 2011.
Lo K.C. and Li L., Acupuncture on Time - Discussions on the Acupuncture-time Thought of “Yellow Emperor's Internal Classic”, 審時知機,按時鍼刺——試論《黃帝內經》中按時鍼刺的學術思想, Taipei Traditional Chinese Medicine International Forum 2012. 2012臺北國際中醫藥學術論壇, Taipei, Tanwan.
Lo K.C., Zhang W. and Li L., Clinical Study on Acupoints Application Treatment of the Three Dog Days Treating Nonacutebronchial Asthma – Randomized Double-blind Placebo Controlled Trial , 2011 Chinese National Conference on Chronabiology. Nanning, China, 2011.


Researcher : Loo TY

List of Research Outputs

Wang Z., Loo T.Y., Wang N., Wang D., YAng D. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By A Medicinal Herb: Sanguisorba officinalis L., Expert Opinion on Biological Therapy,. 2012.


Researcher : Luo J

List of Research Outputs

Li Y., Luo J., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y. and Shen J., Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway, PLoS One. 2011, 6(8): 22901.


Researcher : Man MSC

List of Research Outputs

Zhang Z., Ng R., Man M.S.C., Li T.Y.J., Wong W., Tan Q.R., Wong H.K., Chung K.F., Wong M.T., Tsang W.K.A., Yip K.C., Ziea E. and Wong V.C.W., Dense cranial electroacupuncture stimulation for major depressive disorder: a single-blind, randomized, controlled study, PloS ONE . 2012, 7: e29651.


Researcher : Qi H

List of Research Outputs

Qi H., Chen B., Le X.C. and Rong J., Concomitant induction of heme oxygenase-1 attenuates the cytotoxicity of arsenic species from lumbricus extract in human liver HepG2 cells, Chemistry & Biodiversity. 2012, 9: 739-54.
Qi H., Han Y. and Rong J., Potential roles of PI3K/Akt and Nrf2-Keap1 pathways in regulating hormesis of Z-ligustilide in PC12 cells against oxygen and glucose deprivation, Neuropharmacology. 2012, 62: 1659–1670.
Qi H., Zhao J., Han Y., Lau A.S.Y. and Rong J., Z-Ligustilide Potentiates the Cytotoxicity of Dopamine in Rat Dopaminergic PC12 Cells, Neurotoxicity Research . 2012.


Researcher : Rong J

Project Title:The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy
Investigator(s):Rong J
Department:Medical Faculty
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2006


Project Title:Synergistic neurotoxic effects of (Z)-ligustilide and dopamine in rat dopaminergic cell line PC12: Implications for the pathogenesis of Parkinson’s disease (PD)
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:03/2011


Project Title:16th WORLD CONGRESS ON HEART DISEASE Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) in human neutrophils and its potential in the treatment of myocardial injury
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2011
Completion Date:07/2011


Project Title:Novel role of actin-binding protein α-actinin 4 in the regulation of hydrogen peroxide-induced NF-κB activation by Chinese medicine puerarin
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


List of Research Outputs

Cui W., Li W., Han R., Mak S., Zhang H., Hu S., Rong J. and Han Y., PI3-K/Akt and ERK pathways activated by VEGF play opposite roles in MPP+-induced neuronal apoptosis, Neurochemistry International. London, Elsevier, 2011, 59: 945-53.
Qi H., Chen B., Le X.C. and Rong J., Concomitant induction of heme oxygenase-1 attenuates the cytotoxicity of arsenic species from lumbricus extract in human liver HepG2 cells, Chemistry & Biodiversity. 2012, 9: 739-54.
Qi H., Han Y. and Rong J., Potential roles of PI3K/Akt and Nrf2-Keap1 pathways in regulating hormesis of Z-ligustilide in PC12 cells against oxygen and glucose deprivation, Neuropharmacology. 2012, 62: 1659–1670.
Qi H., Zhao J., Han Y., Lau A.S.Y. and Rong J., Z-Ligustilide Potentiates the Cytotoxicity of Dopamine in Rat Dopaminergic PC12 Cells, Neurotoxicity Research . 2012.
Wei L., Le X.C., Xia Z., Han Y. and Rong J., PHARMACOLOGICAL INDUCTION OF LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE (LTB4DH) IN HUMAN NEUTROPHILS AND ITS POTENTIAL IN THE TREATMENT OF MYOCARDIAL INJURY, the International Academy of Cardiology, 16th WORLD CONGRESS ON HEART DISEASE, Annual Scientific Sessions 2011. Vancouver, BC, Canada.
Wei L., Le X.C., Xia Z., Han Y. and Rong J., Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase in human neutrophils and its potential in the treatment of myocardial injury, Journal of Heart Disease. Cardiology Online, 2011, 8: 66.


Researcher : Shen J

Project Title:Biochemical Society Meeting 679 University of Essex UK - Stress, Signalling and Control Reactive Oxygen Species Mediate Intracellular Cholesterol Accumulation via Modulating Caveolin-1 Pathway in Chinese Hamster Ovary Cells
Investigator(s):Shen J
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2003


Project Title:Interactions of Reactive Nitrogen Species, Caveolins and Matrix Metalloproteinases: A Novel Signal Mechanism in Disruption of Blood Brain Barrier during Ischemic Stroke
Investigator(s):Shen J, Chung SK, So KF, Yang D
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2008
Completion Date:08/2011


Project Title:Elucidating caveolin-1 as a negative modulating protein for proliferation of neural stem/progenitor cells and neural differentiation in post-ischemic brain
Investigator(s):Shen J, Chung SK, So KF
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2010


Project Title:Effects of reactive nitrogen species inhibitors on preventing thrombolysis-induced blood brain barrier disruption and hemorrhagic transformation in cerebral ischemia-reperfusion injury
Investigator(s):Shen J, Yang D, Liu KJ
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2011
Completion Date:03/2012


Project Title:Molecular regulations of reactive nitrogen species inhibitors for preventing thrombolysis-induced blood brain barrier disruption and hemorrhagic transformation in experimental cererbal ischemia-reperfersion models
Investigator(s):Shen J, Cheung RTF, Chung SK, Siu DCW, Yang D
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating proliferation and neuronal differentiation of neural stem/progenitor cells under hypoxic and ischemic conditions
Investigator(s):Shen J, Yang D, So KF
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


Project Title:Using Ski as a molecular target for seeking active compounds from Qingyihuaji (QYHJ) formula for inhibiting pancreatic cancer stem cells
Investigator(s):Shen J, Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2012


List of Research Outputs

Deng R.X., Chan G.C.F., Shen J., Ye J.Y., Ma M., Chen J.L., Liu C., Dee C.M. and Yang M., Astragaloside IV enhanced haematopoiesis via the EGFR-MEK-EKR1/2 signalling pathway., Hong Kong Journal of Paediatrics. 2011;16:217 (Proceedings for Joint Annual Scientific Meeting 2011: The Hong Kong Paediatric Society and American Academy of Pediatrics in conjunction with Hong Kong Paediatric Nurses Association). 2011, 16: 217.
Du L.B., Miao X.X., Jiang Y.G., Jia H.Y., Tian Q., Shen J. and Liu Y., An effective strategy for the synthesis of biocompatible gold nanoparticles using danshensu antioxidant: prevention of cytotoxicity via attenuation of free radical formation., Nanotoxicology. 2012, 6: doi:10.3109/17435390.2011.653415.
Feng Y., Chueng X.M., Wang N. and Shen J., Current Progress on Medicinal Plants and their Biological Properties in Contemporary China. Chapter in Recent Progress in Medicinal Plants, Ethnomedicine: Source & Mechanism-II. Studium Press LLC, USA. 2011, 28.
Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.
Lau W.M., Lee C.D., Li Y., Fung M.Y., Sang Y., Shen J., Chang R.C.C. and So K.F., Polysaccharides from wolfberry prevents corticosterone-induced inhibition of sexual behavior and increases neurogenesis, PLoS One. 2012, 7(4): e33374.
Lee W.S., Xu M., Li Y., Gu Y., Chen J., Wong D., Fung P.C.W. and Shen J., Free cholesterol accumulation impairs antioxidant activities and aggravates apoptotic cell death in menadione-induced oxidative injury., Arch Biochem Biophys. . 2011, 514(1-2): 57-67.
Li Y., Zhuang P.W., Shen B.R., Zhang Y.J. and Shen J., Baicalin promotes neuronal differentiation of neural stem/progenitor cells through modulating p-stat3 and bHLH family protein expression., Brain Research . 2012, 1429: 36-42.
Li Y., Luo J., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y. and Shen J., Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway, PLoS One. 2011, 6(8): 22901.
Li Z.X., Yang D.P., Huang M.L., Hu X.J., Shen J., Zhao Z.M. and Chen J., Chrysomya megacephala (Fabricius) larvae: A new biodiesel resource. , Applied Energy. 2012, 94: 349-354.
Luo Y.L., Zhang C.C., Li P.B., Nie Y.C., Wu H. and Shen J., Naringin attenuates enhanced cough, airway hyperresponsiveness and airway inflammation in a guinea pig model of chronic bronchitis induced by cigarette smoke., International Immunopharmacology. 2012, 13(3): 301-307.
Nie Y.C., Wu H., Li P.B., Luo Y.L., Zhang C.C., Shen J. and Su W.W., Characteristic comparison of three rat models induced by cigarette smoke or combined with LPS: to establish a suitable model for study of airway mucus hypersecretion in chronic obstructive pulmonary disease. , Pulmonary Pharmacology & Therapeutics . 2012.
Pan Y., Hua Y.Q., Liu L.M. and Shen J., 無血清培養法分離并鑒定胰腺癌細胞系BxPC-3中腫瘤干細胞, 中国肿瘤 2012,21 (6): 441-445 . 2012.
Shen J., Acupuncture for post-stroke rehabilitation: Insights form neurobiology, neuroimaging evidence and systemic review of clinical trials. Chairman of the Meeting, Keynote speaker, The First Forum of Integrated Neurology, October 29 -30, Beijing, China . 2011.
Shen J., Drug Discovery from a Classic Chinese Medicinal Formula for Neuroprotection and Neurogenesis in Post-stroke Treatment. Invited speaker, , Sun Yat-sen University, Dec 19-20, 2011, Guangzhou, China. 2011.
Shen J., Recent Development of Medical Imaging Diagnosis and Therapeutic Strategies for Stroke : Opportunities and Challenges for Chinese Medicine at New Ceutury. Invited speaker, . ., Guangzhou University of Traditional Chinese Medicine, Dec 20, 2011, Guangzhou, China. 2011.
Shen J., Cancer stem cells: Implications for novel drug development and understanding therapeutic principles of Chinese herbal medicine for cancer treatment., Markey Cancer Center, University of Kentucky, Lexington, Kentucky, USA. 2012.
Shen J., Caveolin-1 and blood brain barrier permeability: A novel molecular mechanism in cerebral ischemia-reperfusion injury. Invited speaker, Oct 7, 2011, , Brain Imaging Center, The University of New Mexico, Albuquerque, NM, USA . 2011.
Shen J., Caveolin-1 derived from endothelial cells negatively modulates neuronal differentiation of neural progenitor cells in post-ischemic brain injury. , 8th Stem Cell Research & Regenerative Medicine Conference, Stem Cells Summit 2012, Boston, MA, USA. 2012.
Shen J., Current Progress in Medical Imaging Diagnosis and Therapeutic Strategies for Stroke : Opportunities and Challenges for Chinese Medicine , Overseas Outstanding Scholar Lectureship. 2011.
Shen J., Dual Roles of Caveolin-1 in Cerebral Ischemia and Reperfusion Injury: Protection of Blood Brain Barrier but Inhibition of Neurogenesis. Invited speaker, The 17th International Biophysics Congress (IUPAB) & 12th National Biphysical Congress, October 30-November 3, 2011, Beijing, China. 2011.
Shen J., Integrated Medicine: A Cross Talk for Understanding Therapeutic Principles of Traditional Chinese Medicine., College of Pharmacy, The University of New Mexico, Albuquerque, NM 87111, USA. 2012.
Shen J., Reactive nitrogen species: Dual roles for blood brain barrier disruption and brain repairs in cerebral ischemia and reperfusion injury., Acta Biophysica Sinica. 2012, 28(4): 295-306.
Shen J., Strategical reform for enhancing life-time learning ability for Chinese medical students under globalization of Chinese medicine. , Pan- Pearl River Reagion Chinese Medical Education Reform Collaboration Meeting, November 24-27, 2011, Changsha, China.. 2011.
Shen J., 從中醫藥發展史反思中國大陸和香港中醫藥教育和科研發展的方向 , 2011年MCMIA香港中醫藥發展策略研討會, 2011.
Wang N., Wang Z., Mo S.L., Loo T.Y., Wang D.M., Luo H.B., Yang D.P., Chen L.Y., Shen J. and Chen J., Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer. , Breast Cancer Research and Treatment. 2012, 134(3):: 943-55.
Wang Z., Cheng Y., Wang N., Wang D.M., Li Y.W., Han F., Shen J., Yang D.P., Guan X. and Chen J., Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins., Cancer Biology & Therapy . 2012, 13(3): 138-147.
Wang Z., Wang N., Chen J. and Shen J., Emerging Glycolysis Targeting and Drug Discovery from ChineseMedicine in Cancer Therapy, Evidence-Based Complementary and Alternative Medicine. 2012, 2012: Article ID 873175.
Yang D., Wang H., Sun Z. and Shen J., Reagents for Highly Specific Detection of Peroxynitrite, Chinese Patent No. ZL200680045462.9, issued on February 8, 2012. 2012.
Yang L.P., Xu W.C., Shen J., Li J. and Jiang J., Secondary Metabolites Of Genus Astragalus : Structure And Biological Activity Update, Chemistry & Biodiversity . 2012, doi: 10.1002/cbdv.201100444.
Zhao H., Ren C.C., Chen X. and Shen J., From rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemia., Current Drug Targets . 2012, 13(2): 173-187.
Zheng G., Wang X.T., Wang J.Z. and Shen J., 水通道蛋白-4在缺血/缺氧損傷后神經血管單元中的作用, 微循環學雜志, 2011, 2: 112-114.


Researcher : Song J

List of Research Outputs

Lin X., Song J., Shaw P.C., Ng T.B., Sze C.W., Tong Y., Lee C.K.F. and Zhang Y., An Autoimmunized Mouse Model Recapitulates Key Features in the Pathogenesis of SjÖgren’s Syndrome, In: Lin X, Song JX, Shaw PC, Ng TB, Stephen Sze CW, Tong Y, Lee KF, Kalin Zhang YB., International Immunology. 2011 Oct, 23(10): 613-24.. 2011, 23: 613-24.
Song J., Choi M.Y., Wong K.C., Chung W.W., Sze C.W., Ng T.B. and Zhang Y., Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism, Chinese Medicine. 2012, 7: 1-9.
Zhang Y., Sze C.W., Tong Y., Song J., Lee C.K.F., Leung G.P.H., Ng T.B. and Shaw P.C., Anti-parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models. , In: Song JX, Stephen Sze CW, Ng TB, Caivin Lee KF, George Leung PH, Shaw PC, Tong Y, Zhang YB*., Journal of Ethnopharmacology. 2012 Feb 15; 139(3): 698-711. . 2012, 139: 698-711.
Zhang Y., Song J., Choi Y.M., Wong C.K., Chung W.Y., Ho K.L. and Ng T.B., Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells., In: Song JX, Mandy Choi YM, Kavin Wong CK, Winkie Chung WY, Ho KL, Stephen Sze CW, Ng TB, Kalin Zhang YB*., Chinese Medicine. 2012 Jan 21, 7(1): 1-9.. 2012, 7: 1-9.
Zhang Y., Lin X., Song J., Shaw P.C., Ng T.B. and Wong R.N.S., Dendrobium officinale polysaccharides ameliorate the abnormality of aquaporin 5, pro-inflammatory cytokines and inhibit apoptosis in the experimental Sjögren's syndrome mice., In: Lin X, Song JX, Shaw PC, Ng TB, Ricky Wong NS, Stephen Sze CW, Tong Y, Lee KF, Zhang YB*., Int Immunopharmacol. 2011 Sep, 11(12): 2025-32.. 2011, 11: 2025-32.
Zhang Y., Song J. and Choi Y.M., Protective effects of baicalein on rotenone induced apoptosis in SH-SY5Y cells. , In: Yuen Man Mandy CHOI, Juxian SONG, Kalin Yanbo ZHANG, 10th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 26-28, 2011, Shanghai, China.. 2011.
Zhang Y., Tong Y., Sze C.W., Song J. and Ng T.B., Protective effects of chrysotoxine on parkinsonian neurotoxins induced dopaminergic neuronal cell death in sh-sy5y cells., In: Song JX, Stephen Sze CW, Tong Y, Ng TB, Zhang YB., 7th Annual on Cell Based Assays 19 – 20 June 2012, Berlin Estrel Hotel, Berlin, Germany. Organization from informa life science. . 2012.


Researcher : Sze CW

Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CW, Zhang Y, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:12/2009


Project Title:Proteomic study on ovary during menopausal transition
Investigator(s):Sze CW, Tong Y, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:01/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2010


Project Title:Study of Novel Biomarkers for Authenticating the Age of Oriental Ginseng, Chinese Medicinal Herb, using Proteomics Approach
Investigator(s):Sze CW, Tong Y, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:05/2011


Project Title:Characterization of a tissue-selective aromatase modifier: implication for estrogen deficiency diseases
Investigator(s):Sze CW, Tong Y, Lee CKF
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:Mechanistic study of a Steriodogenic Protein from Dioscorea opposite Thunb for cardiovascular protection in menopausal rat model
Investigator(s):Sze CW, Tong Y, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012


List of Research Outputs

Lin X., Song J., Shaw P.C., Ng T.B., Sze C.W., Tong Y., Lee C.K.F. and Zhang Y., An Autoimmunized Mouse Model Recapitulates Key Features in the Pathogenesis of SjÖgren’s Syndrome, In: Lin X, Song JX, Shaw PC, Ng TB, Stephen Sze CW, Tong Y, Lee KF, Kalin Zhang YB., International Immunology. 2011 Oct, 23(10): 613-24.. 2011, 23: 613-24.
Song J., Choi M.Y., Wong K.C., Chung W.W., Sze C.W., Ng T.B. and Zhang Y., Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism, Chinese Medicine. 2012, 7: 1-9.
Sze C.W., Ip C.W., Ng T.B., Zhang Y., Zhang Z., Cheung H.P., Cheng L.Y. and Tong Y., Compatibility of multiple herbal components in Erxian Decoction, a Chinese medicinal formula, for treating osteoporosis, European Journal of Integrative Medicine. 2012, 4: 187-196.
Sze C.W., Cytotoxic study of vinegar-processed Radix Euphorbiae Pekinensis, Radix Euphorbiae Kansui and Artemisia argyi Folium (HK$ 97,430), Donation from Shandong Academy of Chinese Medicine. 山东省中医药研究院; 中药炮制研究室, 2011.
Sze C.W., Cheung H.P., Ng T.B., Zhang Z., Wong K.L., Wong H.K., Hu Y.M., Yow C.M. and Tong Y., Effects of Erxian decoction, a Chinese medicinal formulation, on serum lipid profile in a rat model of menopause, Chinese Medicine . 2011, 6: 40.
Sze C.W., Lead Guest Editor for a Special Issue (Herbal Medicines and Natural Products for Treatment of Endocrine Aging Disorders (EADs)) , Evidence-Based Complementary and Alternative Medicine. 2012.
Sze C.W., Leigh A. and Cheung H.P., Novel Bioactive Protein isolated from Chinese Yam (Dioscorea opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome, Hong Kong Summit - Science Park. 2012.
Wang D., Wong H.K., Zhang L., McAlonan G.M., Wang X.M., Sze C.W., Feng Y. and Zhang Z., Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemia, Progress in Neuro-Psychopharmacology & Biological Psychiatry . 2012, in press: n/a.
Zhang Y., Sze C.W., Ye X.J., Ng T.B., Feng E.F., Wong J. and Pan W., A Protein from Red Cabbage (Brassica oleracea) Seeds withs Antifungal, Antibacterial and Anticancer Activities. , In: Ye XJ, Ng TB, Fang EF, Wong J, Pan W, Sze CW, Zhang, YB*., J Agric Food Chem. 2011 Sep, 59(18): 10232-8.. 2011, 95: 10232-8.
Zhang Y., Sze C.W., Tong Y., Song J., Lee C.K.F., Leung G.P.H., Ng T.B. and Shaw P.C., Anti-parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models. , In: Song JX, Stephen Sze CW, Ng TB, Caivin Lee KF, George Leung PH, Shaw PC, Tong Y, Zhang YB*., Journal of Ethnopharmacology. 2012 Feb 15; 139(3): 698-711. . 2012, 139: 698-711.
Zhang Y., Sze C.W., Tong Y., Cai Y., Liu J., Lee C.K.F. and Leung G.P.H., Comparative Analysis of Caffeoylquinic Acids and Lignans in Roots and Seeds among Various Burdock (Arctium lappa) Genotypes with High Antioxidant Activity., In: Liu JY, Cai YZ, Wong RNS, Lee KF, Tang CY, Sze CW, Tong Y and Zhang YB*. , J Agri Food Chem. 2012 April, 60 (16): 4067–75. . 2012, 60: 4067–75.
Zhang Y., Tong Y., Sze C.W., Tang S.C.W., Ho J.C.M., Ng T.B. and Liao Q.X., Investigation of therapeutic efficacy and mechanisms of polysaccharide of Dendrobium officinale in alleviating cigarette-induced pulmonary inflammation. , In: Zhang YB*, Tong Yao, Sze CW, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Support Programme, the Government of the Hong Kong Special Administrative Region. (Project code: ITS/313/11).. 2012.
Zhang Y., Sze C.W. and Tong Y., PI: (HKD200,000.00) Investigating on Efficacy in Xeroma and Molecular Mechanism of Dendroxine, a Novel Herbal Compound. , In: Zhang YB*, Tong Y, Sze CW, The Stanley Ho Alumni Challenge received a Gold Award, HKU (Project No. 20730472). 2011.
Zhang Y., Sze C.W., Tong Y., Tang S.C.W., Ho J.C.M., Ng T.B. and Liao X.Q., PI: HK$223,300.00 (April 27, 2012). Zhang YB*, Stephen Sze CW, Tong Y, Ng TB, Liao XQ, Ho CM, Tang CW. Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation. , In: Zhang YB*, Stephen Sze CW, Tong Y, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Fund Internship Programme of Hong Kong (Project code: InP/066/12).. 2012.
Zhang Y., Sze C.W., Tong Y., Ng T., Liao X., Tang S.C.W. and Ho J.C.M., PI: HK$826,701.00 (March 23, 2012). Investigation of therapeutic efficacy and mechanisms of polysaccharide of Dendrobium officinale in alleviating cigarette-induced pulmonary inflammation. , In: Zhang YB*, Tong Yao, Sze CW, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Support Programme, the Government of the Hong Kong Special Administrative Region (Project code: ITS/313/11).. 2012.
Zhang Y., Sze C.W., Tong Y. and Feng F., PI: HK$95,500.00 (April 26, 2012). QSAR and Transport Mechanism Studies of Chrysotoxin, a Novel Nuroprotective Compound., In: PI: HK$95,500.00. Zhang YB*, Feng Feng, Tong Y, Stephen Sze CW. , Seed Funding Programme for Basic Research from HKU (201111159043).. 2012.
Zhang Y., Sze C.W. and Tong Y., PI: HKD21,000.00 (Sep 2011). RGF Incentive Award., In: Zhang YB*, Tong Y, Sze CW., University Research committee (Project No. 10209113). . 2011.
Zhang Y., Tong Y., Sze C.W., Song J. and Ng T.B., Protective effects of chrysotoxine on parkinsonian neurotoxins induced dopaminergic neuronal cell death in sh-sy5y cells., In: Song JX, Stephen Sze CW, Tong Y, Ng TB, Zhang YB., 7th Annual on Cell Based Assays 19 – 20 June 2012, Berlin Estrel Hotel, Berlin, Germany. Organization from informa life science. . 2012.
Zhang Y., Tong Y., Sze C.W., Liu J., Ng T.B., Wong H. and Ye X.J., Review of research on Dendrobium, a prized folk medicine., In: Tzi Bun Ng, Jingyi Liu, Jack Ho Wong, Xiujuan Ye, Stephen Cho Wing Sze, Yao Tong, Kalin Yanbo Zhang*., Appl Microbiol Biotechnol. 2012, 93:1795–1803. . 2012, 93: 1795-1803.
Zhang Y., Sze C.W., Cheung H.P. and Ho K.L., Study on Anti-cancer Effect of 6-Hydroxydendroxine, A Chemical Component from Dendrobium nobile Lindl., on HT-29 Human Colorectal Cancer Cells. , In: Ho Ka-Lai, Cheung Ho-Pan, Stephen Sze Cho-Wing, Kalin Zhang Yanbo. , 18th Hong Kong International Cancer Congress to be held on 3 – 5 November, 2011. Cheung Kung Hai Conference Centre, Li Ka Shing Faculty of Medicine, The University of Hong Kong. Hong Kong.. 2011.
Zhang Y., Sze C.W. and Tong Y., Study on Mei Xing Su to improve Alzheimer’s disease. , Contract research. Funding from Orital Int’l Health Products Co., Ltd. (Hong Kong). Agreement code: RS100477. Project No. 20006390. . 2012.
Zhong L., Tong Y., Tang G.W.K., Choi W.K. and Sze C.W., A Randomized Placebo-controlled trial on the effectiveness of a Chinese herbal formula to alleviate menopausal symptoms, The 10th Meeting of Consortium for Globalization of Chinese Medicine. 2011, 168.
孫 立.立., 楊 書.斌., 仲 英., Sze C.W. and 袁 振.海., 一种治療結腸癌的药物及其制备方法, 中華人民共和國國家知識產權局, 2011.
孫 立.立., 楊 書.斌., Sze C.W., 周 倩., 夏 紅.旻. and 石 典.花., 一种治療乳腺癌的药物及其制备方法, 中華人民共和國國家知識產權局, 2011.


Researcher : Tong Y

Project Title:A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials
Investigator(s):Tong Y, Shen J, Zhong L, Diu CK
Department:School of Chinese Medicine
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:09/2009


Project Title:Mechanistic Study of Erxian Decoction on serum lipid profile of Menopausal Rat Model
Investigator(s):Tong Y, Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:12/2010
Completion Date:11/2011


Project Title:A pure chemical isolated from cortex phellodendri as a potential drug candidate for treating menopausal syndrome
Investigator(s):Tong Y, Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2011


List of Research Outputs

Cheung F., Feng Y., Wang M.N., Yuen R.M.F., Tong Y. and Wong V.C.W., Effectiveness of Chinese herbal medicine in treating liver fibrosis: a systematic review and meta-analysis of randomized controlled trials., Chin Med, 2012, 7(1):5.
Feng Y., Wang M.N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on bear bile and coptis. Handbook with programme 19, 8th world congress of Chinese Medicine. 2011.
Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.
Li Y., Luo J., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y. and Shen J., Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway, PLoS One. 2011, 6(8): 22901.
Lin X., Song J., Shaw P.C., Ng T.B., Sze C.W., Tong Y., Lee C.K.F. and Zhang Y., An Autoimmunized Mouse Model Recapitulates Key Features in the Pathogenesis of SjÖgren’s Syndrome, In: Lin X, Song JX, Shaw PC, Ng TB, Stephen Sze CW, Tong Y, Lee KF, Kalin Zhang YB., International Immunology. 2011 Oct, 23(10): 613-24.. 2011, 23: 613-24.
Sze C.W., Ip C.W., Ng T.B., Zhang Y., Zhang Z., Cheung H.P., Cheng L.Y. and Tong Y., Compatibility of multiple herbal components in Erxian Decoction, a Chinese medicinal formula, for treating osteoporosis, European Journal of Integrative Medicine. 2012, 4: 187-196.
Sze C.W., Cheung H.P., Ng T.B., Zhang Z., Wong K.L., Wong H.K., Hu Y.M., Yow C.M. and Tong Y., Effects of Erxian decoction, a Chinese medicinal formulation, on serum lipid profile in a rat model of menopause, Chinese Medicine . 2011, 6: 40.
Tong Y., Current Research Status on Standardization of TCM Diagnosis in World, Annual meeting of Integrative Medical Association: TCM diagnosis branch. Shanghai, 2011.
Tong Y., Mechanism Study of A Chinese Medicinal Decoction - Tian-Xian Liquid (TXL) in Human colorectal cancer (HT-29) in vivo and in vitro., Summer Workshop for TCM postgraduate Students. Shanghai, 2011.
Tong Y., Summary Report of Standardization and Objectification of TCM Diagnosis, The 10th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Shanghai, 2011.
Tong Y., Zhong L. and Feng Y., The Implementation of PBL in Chinese Medicine Program at The University of Hong Kong, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.
Tong Y., The Implementation of PBL in Chinese Medicine Program at the University of Hong Kong, The 10th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Shanghai, 2011.
Tong Y., The role of traditional Chinese medicine in the management of Arthritis, Annual meeting of HK Rheumatoid Arthritis Association. Hong Kong, 2011.
Wang N., Feng Y., Lau E.P., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W. and Tsao G.S.W., F-actin reorganization and inactivation of rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration., Integrate Cancer Therapy. 2011.
Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, Journal of cellular biochemistry. 2011.
Zhang Y., Sze C.W., Tong Y., Song J., Lee C.K.F., Leung G.P.H., Ng T.B. and Shaw P.C., Anti-parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models. , In: Song JX, Stephen Sze CW, Ng TB, Caivin Lee KF, George Leung PH, Shaw PC, Tong Y, Zhang YB*., Journal of Ethnopharmacology. 2012 Feb 15; 139(3): 698-711. . 2012, 139: 698-711.
Zhang Y., Sze C.W., Tong Y., Cai Y., Liu J., Lee C.K.F. and Leung G.P.H., Comparative Analysis of Caffeoylquinic Acids and Lignans in Roots and Seeds among Various Burdock (Arctium lappa) Genotypes with High Antioxidant Activity., In: Liu JY, Cai YZ, Wong RNS, Lee KF, Tang CY, Sze CW, Tong Y and Zhang YB*. , J Agri Food Chem. 2012 April, 60 (16): 4067–75. . 2012, 60: 4067–75.
Zhang Y., Tong Y., Sze C.W., Tang S.C.W., Ho J.C.M., Ng T.B. and Liao Q.X., Investigation of therapeutic efficacy and mechanisms of polysaccharide of Dendrobium officinale in alleviating cigarette-induced pulmonary inflammation. , In: Zhang YB*, Tong Yao, Sze CW, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Support Programme, the Government of the Hong Kong Special Administrative Region. (Project code: ITS/313/11).. 2012.
Zhang Y., Sze C.W. and Tong Y., PI: (HKD200,000.00) Investigating on Efficacy in Xeroma and Molecular Mechanism of Dendroxine, a Novel Herbal Compound. , In: Zhang YB*, Tong Y, Sze CW, The Stanley Ho Alumni Challenge received a Gold Award, HKU (Project No. 20730472). 2011.
Zhang Y., Sze C.W., Tong Y., Tang S.C.W., Ho J.C.M., Ng T.B. and Liao X.Q., PI: HK$223,300.00 (April 27, 2012). Zhang YB*, Stephen Sze CW, Tong Y, Ng TB, Liao XQ, Ho CM, Tang CW. Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation. , In: Zhang YB*, Stephen Sze CW, Tong Y, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Fund Internship Programme of Hong Kong (Project code: InP/066/12).. 2012.
Zhang Y., Sze C.W., Tong Y., Ng T., Liao X., Tang S.C.W. and Ho J.C.M., PI: HK$826,701.00 (March 23, 2012). Investigation of therapeutic efficacy and mechanisms of polysaccharide of Dendrobium officinale in alleviating cigarette-induced pulmonary inflammation. , In: Zhang YB*, Tong Yao, Sze CW, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Support Programme, the Government of the Hong Kong Special Administrative Region (Project code: ITS/313/11).. 2012.
Zhang Y., Sze C.W., Tong Y. and Feng F., PI: HK$95,500.00 (April 26, 2012). QSAR and Transport Mechanism Studies of Chrysotoxin, a Novel Nuroprotective Compound., In: PI: HK$95,500.00. Zhang YB*, Feng Feng, Tong Y, Stephen Sze CW. , Seed Funding Programme for Basic Research from HKU (201111159043).. 2012.
Zhang Y., Sze C.W. and Tong Y., PI: HKD21,000.00 (Sep 2011). RGF Incentive Award., In: Zhang YB*, Tong Y, Sze CW., University Research committee (Project No. 10209113). . 2011.
Zhang Y., Tong Y., Sze C.W., Song J. and Ng T.B., Protective effects of chrysotoxine on parkinsonian neurotoxins induced dopaminergic neuronal cell death in sh-sy5y cells., In: Song JX, Stephen Sze CW, Tong Y, Ng TB, Zhang YB., 7th Annual on Cell Based Assays 19 – 20 June 2012, Berlin Estrel Hotel, Berlin, Germany. Organization from informa life science. . 2012.
Zhang Y., Tong Y., Sze C.W., Liu J., Ng T.B., Wong H. and Ye X.J., Review of research on Dendrobium, a prized folk medicine., In: Tzi Bun Ng, Jingyi Liu, Jack Ho Wong, Xiujuan Ye, Stephen Cho Wing Sze, Yao Tong, Kalin Yanbo Zhang*., Appl Microbiol Biotechnol. 2012, 93:1795–1803. . 2012, 93: 1795-1803.
Zhang Y., Sze C.W. and Tong Y., Study on Mei Xing Su to improve Alzheimer’s disease. , Contract research. Funding from Orital Int’l Health Products Co., Ltd. (Hong Kong). Agreement code: RS100477. Project No. 20006390. . 2012.
Zhong L., Tong Y., Tang G.W.K., Choi W.K. and Sze C.W., A Randomized Placebo-controlled trial on the effectiveness of a Chinese herbal formula to alleviate menopausal symptoms, The 10th Meeting of Consortium for Globalization of Chinese Medicine. 2011, 168.
Zhong L. and Tong Y., Can Chinese Herbal Medicine alleviate menopausal symptoms in Hong Kong Chinese Women? A pilot study on effects of a Chinese herbal formula on menopause. , The 14th World Congress on Controversies in Obstetrics, Gynecology and Infertility. 2011, 176.
Zhong L., Tong Y., Chen H., Cho W. and Meng X., The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: a systematic review and meta-analysis, Complementary Therapies in Medicine. 2012, 20: 240-252.
Zhong L., Tong Y. and Feng Y., The implementation of PBL in Chinese Medicine Program at the University of Hong Kong, The 10th Meeting of Consortium for Globalization of Chinese Medicine. 2011, 189.


Researcher : Wang D

List of Research Outputs

Wang D., Wong H.K., Zhang L., McAlonan G.M., Wang X.M., Sze C.W., Feng Y. and Zhang Z., Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemia, Progress in Neuro-Psychopharmacology & Biological Psychiatry . 2012, in press: n/a.


Researcher : Wang MN

List of Research Outputs

Cheung F., Feng Y., Wang M.N., Yuen R.M.F., Tong Y. and Wong V.C.W., Effectiveness of Chinese herbal medicine in treating liver fibrosis: a systematic review and meta-analysis of randomized controlled trials., Chin Med, 2012, 7(1):5.
Feng Y., Wang M.N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on bear bile and coptis. Handbook with programme 19, 8th world congress of Chinese Medicine. 2011.
Feng Y., Wang M.N., Ye X., Li H., Cheung F. and Nagamatsu T., Hepatoprotective effect and its possible mechanism of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced chronic liver hepatotoxicity in rats, Journal of Ethnopharmacology, 2011, 138(3):683-90.
Feng Y.G., Wang M.N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies . 2011.
To C.S., Liew C., Wang X., Wang M.N. and Feng Y., Comparison of Components and Anti-Liver Cancer Activity in Vitro between Huanglian and Yunlian, Journal of Bioequivalence & Bioavailability, 2012.
Wang M.N., Pan W., Zhu M., Zhanf M., Hao X., Laing G. and Feng Y., Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signaling in human hepatocellular carcinoma cells, British Journal of Pharmacology, 2011, 164: 731-742.
Wang M.N., Pan W., Zhu M., Zhanf M., Hao X., Lian G. and Feng Y., Fangchinoline is a potential anti-cancer drug by inducing autophagic cell death in heaptocellular carcinoma cells, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.
Wang X., Feng Y., Wang M.N., Cheung F. and Wong C.W., Recent Progress on Anti-Liver Fibrosis Candidates in Patents of Herbal Medicinal Products., Recent Pat Food Nutr Agric., 2012.
Zhu M., Wang M.N., Tsao G.S.W. and Feng Y., miR-21 and miR-23a were altered by Coptidis Rhizoma Aqueous Extract in Human Liver Cancer Cells, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.


Researcher : Wang N

List of Research Outputs

Chen J., Wang N. and Wang Z., Targeting tumor angiogenesis: insights from Chinese Medicine , OOTR. 2012.
Feng Y., Chueng X.M., Wang N. and Shen J., Current Progress on Medicinal Plants and their Biological Properties in Contemporary China. Chapter in Recent Progress in Medicinal Plants, Ethnomedicine: Source & Mechanism-II. Studium Press LLC, USA. 2011, 28.
Feng Y.G., Wang N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies (pp332-362). 2011.
Wang N., Feng Y., Lau E.P., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W. and Tsao G.S.W., F-actin reorganization and inactivation of rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration., Integrate Cancer Therapy. 2011.
Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, Journal of cellular biochemistry. 2011.
Wang N., Wang Z., Mo S.L., Loo T.Y., Wang D.M., Luo H.B., Yang D.P., Chen L.Y., Shen J. and Chen J., Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer. , Breast Cancer Research and Treatment. 2012, 134(3):: 943-55.
Wang Z., Cheng Y., Wang N., Wang D.M., Li Y.W., Han F., Shen J., Yang D.P., Guan X. and Chen J., Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins., Cancer Biology & Therapy . 2012, 13(3): 138-147.
Wang Z., Wang N., Chen J. and Shen J., Emerging Glycolysis Targeting and Drug Discovery from ChineseMedicine in Cancer Therapy, Evidence-Based Complementary and Alternative Medicine. 2012, 2012: Article ID 873175.
Wang Z., Loo T.Y., Wang N., Wang D., YAng D. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By A Medicinal Herb: Sanguisorba officinalis L., Expert Opinion on Biological Therapy,. 2012.


Researcher : Wang N

List of Research Outputs

Chen J., Wang N. and Wang Z., Targeting tumor angiogenesis: insights from Chinese Medicine , OOTR. 2012.
Feng Y., Chueng X.M., Wang N. and Shen J., Current Progress on Medicinal Plants and their Biological Properties in Contemporary China. Chapter in Recent Progress in Medicinal Plants, Ethnomedicine: Source & Mechanism-II. Studium Press LLC, USA. 2011, 28.
Feng Y.G., Wang N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies (pp332-362). 2011.
Wang N., Feng Y., Lau E.P., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W. and Tsao G.S.W., F-actin reorganization and inactivation of rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration., Integrate Cancer Therapy. 2011.
Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, Journal of cellular biochemistry. 2011.
Wang N., Wang Z., Mo S.L., Loo T.Y., Wang D.M., Luo H.B., Yang D.P., Chen L.Y., Shen J. and Chen J., Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer. , Breast Cancer Research and Treatment. 2012, 134(3):: 943-55.
Wang Z., Cheng Y., Wang N., Wang D.M., Li Y.W., Han F., Shen J., Yang D.P., Guan X. and Chen J., Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins., Cancer Biology & Therapy . 2012, 13(3): 138-147.
Wang Z., Wang N., Chen J. and Shen J., Emerging Glycolysis Targeting and Drug Discovery from ChineseMedicine in Cancer Therapy, Evidence-Based Complementary and Alternative Medicine. 2012, 2012: Article ID 873175.
Wang Z., Loo T.Y., Wang N., Wang D., YAng D. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By A Medicinal Herb: Sanguisorba officinalis L., Expert Opinion on Biological Therapy,. 2012.


Researcher : Wang TT

List of Research Outputs

Li Y., Luo J., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y. and Shen J., Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway, PLoS One. 2011, 6(8): 22901.


Researcher : Wang X

List of Research Outputs

To C.S., Liew C., Wang X., Wang M.N. and Feng Y., Comparison of Components and Anti-Liver Cancer Activity in Vitro between Huanglian and Yunlian, Journal of Bioequivalence & Bioavailability, 2012.
Wang X., Feng Y., Wang M.N., Cheung F. and Wong C.W., Recent Progress on Anti-Liver Fibrosis Candidates in Patents of Herbal Medicinal Products., Recent Pat Food Nutr Agric., 2012.


Researcher : Wang Z

List of Research Outputs

Chen J., Wang N. and Wang Z., Targeting tumor angiogenesis: insights from Chinese Medicine , OOTR. 2012.
Wang N., Wang Z., Mo S.L., Loo T.Y., Wang D.M., Luo H.B., Yang D.P., Chen L.Y., Shen J. and Chen J., Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer. , Breast Cancer Research and Treatment. 2012, 134(3):: 943-55.
Wang Z., Cheng Y., Wang N., Wang D.M., Li Y.W., Han F., Shen J., Yang D.P., Guan X. and Chen J., Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins., Cancer Biology & Therapy . 2012, 13(3): 138-147.
Wang Z., Wang N., Chen J. and Shen J., Emerging Glycolysis Targeting and Drug Discovery from ChineseMedicine in Cancer Therapy, Evidence-Based Complementary and Alternative Medicine. 2012, 2012: Article ID 873175.
Wang Z., Loo T.Y., Wang N., Wang D., YAng D. and Chen J., Inhibition of Breast Cancer Growth and Angiogenesis By A Medicinal Herb: Sanguisorba officinalis L., Expert Opinion on Biological Therapy,. 2012.


Researcher : Wei L

List of Research Outputs

Wei L., Le X.C., Xia Z., Han Y. and Rong J., Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase in human neutrophils and its potential in the treatment of myocardial injury, Journal of Heart Disease. Cardiology Online, 2011, 8: 66.


Researcher : Wong HK

List of Research Outputs

Sze C.W., Cheung H.P., Ng T.B., Zhang Z., Wong K.L., Wong H.K., Hu Y.M., Yow C.M. and Tong Y., Effects of Erxian decoction, a Chinese medicinal formulation, on serum lipid profile in a rat model of menopause, Chinese Medicine . 2011, 6: 40.
Wang D., Wong H.K., Zhang L., McAlonan G.M., Wang X.M., Sze C.W., Feng Y. and Zhang Z., Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemia, Progress in Neuro-Psychopharmacology & Biological Psychiatry . 2012, in press: n/a.
Zhang Z., Ng R., Man M.S.C., Li T.Y.J., Wong W., Tan Q.R., Wong H.K., Chung K.F., Wong M.T., Tsang W.K.A., Yip K.C., Ziea E. and Wong V.C.W., Dense cranial electroacupuncture stimulation for major depressive disorder: a single-blind, randomized, controlled study, PloS ONE . 2012, 7: e29651.


Researcher : Wong VCW

List of Research Outputs

Cheung F., Feng Y., Wang M.N., Yuen R.M.F., Tong Y. and Wong V.C.W., Effectiveness of Chinese herbal medicine in treating liver fibrosis: a systematic review and meta-analysis of randomized controlled trials., Chin Med, 2012, 7(1):5.
Zhang Z., Ng R., Man M.S.C., Li T.Y.J., Wong W., Tan Q.R., Wong H.K., Chung K.F., Wong M.T., Tsang W.K.A., Yip K.C., Ziea E. and Wong V.C.W., Dense cranial electroacupuncture stimulation for major depressive disorder: a single-blind, randomized, controlled study, PloS ONE . 2012, 7: e29651.


Researcher : Wu H

List of Research Outputs

Luo Y.L., Zhang C.C., Li P.B., Nie Y.C., Wu H. and Shen J., Naringin attenuates enhanced cough, airway hyperresponsiveness and airway inflammation in a guinea pig model of chronic bronchitis induced by cigarette smoke., International Immunopharmacology. 2012, 13(3): 301-307.
Nie Y.C., Wu H., Li P.B., Luo Y.L., Zhang C.C., Shen J. and Su W.W., Characteristic comparison of three rat models induced by cigarette smoke or combined with LPS: to establish a suitable model for study of airway mucus hypersecretion in chronic obstructive pulmonary disease. , Pulmonary Pharmacology & Therapeutics . 2012.


Researcher : Wu J

Project Title:Anti-cystic hyperplasia of breast herbal medicine research
Investigator(s):Wu J, Chow LWC
Department:School of Chinese Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:05/2001


Project Title:Anti-prostatomegaly herbal medicine research
Investigator(s):Wu J, Leung SYL
Department:School of Chinese Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:06/2001




Researcher : Xu M

List of Research Outputs

Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.
Lee W.S., Xu M., Li Y., Gu Y., Chen J., Wong D., Fung P.C.W. and Shen J., Free cholesterol accumulation impairs antioxidant activities and aggravates apoptotic cell death in menadione-induced oxidative injury., Arch Biochem Biophys. . 2011, 514(1-2): 57-67.


Researcher : Ye X

List of Research Outputs

Feng Y., Wang M.N., Ye X., Li H., Cheung F. and Nagamatsu T., Hepatoprotective effect and its possible mechanism of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced chronic liver hepatotoxicity in rats, Journal of Ethnopharmacology, 2011, 138(3):683-90.


Researcher : Yiu YM

List of Research Outputs

Yiu Y.M., Acupuncture Combined with Herb Treatment of Endometriosis Dysmenorrhea, Fourth International Academic Conference of Chinese Gynecology . 第四届國際中醫婦科學術大會, 2011.
Yiu Y.M. and Lu H.L., He-Ne Laser auricular irradiation acupuncture for treatment of Acne Vulgaris, 氦-氖激光耳穴照射治療尋常型痤瘡, 2012 Xian TCMC International Academic Summit Symposium. 2012, 111-113.
Yiu Y.M., Tuina Educational Reform and Practice, 推拿學教學改革的 探索與實踐, In: XB Qu, CHANGCHUN ZHONGYIYAO DAXUE XUEBAO. 長春中醫藥大學學報, CHANGCHUN, 2012, 28: 753.


Researcher : Zhang W

List of Research Outputs

Lo K.C., Zhang W. and Li L., Clinical Study on Acupoints Application Treatment of the Three Dog Days Treating Nonacutebronchial Asthma – Randomized Double-blind Placebo Controlled Trial , 2011 Chinese National Conference on Chronabiology. Nanning, China, 2011.
Qiu T., Li L. and Zhang W., Advance in Clinical Study of Treating Rheumatoid Arthritis with Acupuncture and Moxibustion, 針灸治療類風濕性關節炎的臨床研究進展, In: 香港註冊中醫學會,中國中醫雜誌社, Hong Kong Chinese Medicine Journal. 香港中醫雜誌, 香港, 香港中醫雜誌出版部, 2011, 6(4): 74-78, 82.
Zhang W. and Li L., The Clinical Study of Tian Jiu Therapy on Treating Asthma, The 10th Meeting of The Consortium for Globalization of Chinese Medicine (CGCM) . Shanghai, China, 2011.


Researcher : Zhang Y

Project Title:Industrialization Generation Artemisinin, a Specific Compound from Artemisia annua of Chinese Herb Against Malaria by Plant Cell Culture
Investigator(s):Zhang Y, Tong Y, Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:05/2011
Completion Date:04/2012


Project Title:Investigation of the Mechanism of Aquaporin 5 in Pulmonary Inflammation
Investigator(s):Zhang Y, Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation
Investigator(s):Zhang Y, Sze CW, Tong Y, Ho JCM, Tang SCW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:05/2012


Project Title:Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation (ITS/313/11)
Investigator(s):Zhang Y, Sze CW, Tong Y, Ho JCM, Tang SCW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:05/2012


Project Title:Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation
Investigator(s):Zhang Y, Sze CW, Tong Y, Ho JCM, Tang SCW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:05/2012


Project Title:QSAR and Transport Mechanism Studies of Chrysotoxin, a Novel Nuroprotective Compound
Investigator(s):Zhang Y, Tong Y, Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Lin X., Song J., Shaw P.C., Ng T.B., Sze C.W., Tong Y., Lee C.K.F. and Zhang Y., An Autoimmunized Mouse Model Recapitulates Key Features in the Pathogenesis of SjÖgren’s Syndrome, In: Lin X, Song JX, Shaw PC, Ng TB, Stephen Sze CW, Tong Y, Lee KF, Kalin Zhang YB., International Immunology. 2011 Oct, 23(10): 613-24.. 2011, 23: 613-24.
Song J., Choi M.Y., Wong K.C., Chung W.W., Sze C.W., Ng T.B. and Zhang Y., Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism, Chinese Medicine. 2012, 7: 1-9.
Sze C.W., Ip C.W., Ng T.B., Zhang Y., Zhang Z., Cheung H.P., Cheng L.Y. and Tong Y., Compatibility of multiple herbal components in Erxian Decoction, a Chinese medicinal formula, for treating osteoporosis, European Journal of Integrative Medicine. 2012, 4: 187-196.
Zhang Y., Sze C.W., Ye X.J., Ng T.B., Feng E.F., Wong J. and Pan W., A Protein from Red Cabbage (Brassica oleracea) Seeds withs Antifungal, Antibacterial and Anticancer Activities. , In: Ye XJ, Ng TB, Fang EF, Wong J, Pan W, Sze CW, Zhang, YB*., J Agric Food Chem. 2011 Sep, 59(18): 10232-8.. 2011, 95: 10232-8.
Zhang Y., Sze C.W., Tong Y., Song J., Lee C.K.F., Leung G.P.H., Ng T.B. and Shaw P.C., Anti-parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models. , In: Song JX, Stephen Sze CW, Ng TB, Caivin Lee KF, George Leung PH, Shaw PC, Tong Y, Zhang YB*., Journal of Ethnopharmacology. 2012 Feb 15; 139(3): 698-711. . 2012, 139: 698-711.
Zhang Y., Song J., Choi Y.M., Wong C.K., Chung W.Y., Ho K.L. and Ng T.B., Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells., In: Song JX, Mandy Choi YM, Kavin Wong CK, Winkie Chung WY, Ho KL, Stephen Sze CW, Ng TB, Kalin Zhang YB*., Chinese Medicine. 2012 Jan 21, 7(1): 1-9.. 2012, 7: 1-9.
Zhang Y., Sze C.W., Tong Y., Cai Y., Liu J., Lee C.K.F. and Leung G.P.H., Comparative Analysis of Caffeoylquinic Acids and Lignans in Roots and Seeds among Various Burdock (Arctium lappa) Genotypes with High Antioxidant Activity., In: Liu JY, Cai YZ, Wong RNS, Lee KF, Tang CY, Sze CW, Tong Y and Zhang YB*. , J Agri Food Chem. 2012 April, 60 (16): 4067–75. . 2012, 60: 4067–75.
Zhang Y., Lin X., Song J., Shaw P.C., Ng T.B. and Wong R.N.S., Dendrobium officinale polysaccharides ameliorate the abnormality of aquaporin 5, pro-inflammatory cytokines and inhibit apoptosis in the experimental Sjögren's syndrome mice., In: Lin X, Song JX, Shaw PC, Ng TB, Ricky Wong NS, Stephen Sze CW, Tong Y, Lee KF, Zhang YB*., Int Immunopharmacol. 2011 Sep, 11(12): 2025-32.. 2011, 11: 2025-32.
Zhang Y., Li M., But P. and Shaw P.C., Forensically informative nucleotide sequencing (FINS) for the authentication of Chinese medicinal materials., In: M Li, Kalin YB Zhang, Paul PH But, PC Shaw*., Chinese Medicine. 2012 April, 6:42-8.. 2012, 6: 42-8.
Zhang Y., Tong Y., Sze C.W., Tang S.C.W., Ho J.C.M., Ng T.B. and Liao Q.X., Investigation of therapeutic efficacy and mechanisms of polysaccharide of Dendrobium officinale in alleviating cigarette-induced pulmonary inflammation. , In: Zhang YB*, Tong Yao, Sze CW, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Support Programme, the Government of the Hong Kong Special Administrative Region. (Project code: ITS/313/11).. 2012.
Zhang Y., Sze C.W. and Tong Y., PI: (HKD200,000.00) Investigating on Efficacy in Xeroma and Molecular Mechanism of Dendroxine, a Novel Herbal Compound. , In: Zhang YB*, Tong Y, Sze CW, The Stanley Ho Alumni Challenge received a Gold Award, HKU (Project No. 20730472). 2011.
Zhang Y., Sze C.W., Tong Y., Tang S.C.W., Ho J.C.M., Ng T.B. and Liao X.Q., PI: HK$223,300.00 (April 27, 2012). Zhang YB*, Stephen Sze CW, Tong Y, Ng TB, Liao XQ, Ho CM, Tang CW. Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation. , In: Zhang YB*, Stephen Sze CW, Tong Y, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Fund Internship Programme of Hong Kong (Project code: InP/066/12).. 2012.
Zhang Y., Sze C.W., Tong Y., Ng T., Liao X., Tang S.C.W. and Ho J.C.M., PI: HK$826,701.00 (March 23, 2012). Investigation of therapeutic efficacy and mechanisms of polysaccharide of Dendrobium officinale in alleviating cigarette-induced pulmonary inflammation. , In: Zhang YB*, Tong Yao, Sze CW, Ng TB, Liao XQ, Ho CM, Tang CW., Innovation and Technology Support Programme, the Government of the Hong Kong Special Administrative Region (Project code: ITS/313/11).. 2012.
Zhang Y., Sze C.W., Tong Y. and Feng F., PI: HK$95,500.00 (April 26, 2012). QSAR and Transport Mechanism Studies of Chrysotoxin, a Novel Nuroprotective Compound., In: PI: HK$95,500.00. Zhang YB*, Feng Feng, Tong Y, Stephen Sze CW. , Seed Funding Programme for Basic Research from HKU (201111159043).. 2012.
Zhang Y., Sze C.W. and Tong Y., PI: HKD21,000.00 (Sep 2011). RGF Incentive Award., In: Zhang YB*, Tong Y, Sze CW., University Research committee (Project No. 10209113). . 2011.
Zhang Y., Song J. and Choi Y.M., Protective effects of baicalein on rotenone induced apoptosis in SH-SY5Y cells. , In: Yuen Man Mandy CHOI, Juxian SONG, Kalin Yanbo ZHANG, 10th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Aug 26-28, 2011, Shanghai, China.. 2011.
Zhang Y., Tong Y., Sze C.W., Song J. and Ng T.B., Protective effects of chrysotoxine on parkinsonian neurotoxins induced dopaminergic neuronal cell death in sh-sy5y cells., In: Song JX, Stephen Sze CW, Tong Y, Ng TB, Zhang YB., 7th Annual on Cell Based Assays 19 – 20 June 2012, Berlin Estrel Hotel, Berlin, Germany. Organization from informa life science. . 2012.
Zhang Y., Tong Y., Sze C.W., Liu J., Ng T.B., Wong H. and Ye X.J., Review of research on Dendrobium, a prized folk medicine., In: Tzi Bun Ng, Jingyi Liu, Jack Ho Wong, Xiujuan Ye, Stephen Cho Wing Sze, Yao Tong, Kalin Yanbo Zhang*., Appl Microbiol Biotechnol. 2012, 93:1795–1803. . 2012, 93: 1795-1803.
Zhang Y., Sze C.W., Cheung H.P. and Ho K.L., Study on Anti-cancer Effect of 6-Hydroxydendroxine, A Chemical Component from Dendrobium nobile Lindl., on HT-29 Human Colorectal Cancer Cells. , In: Ho Ka-Lai, Cheung Ho-Pan, Stephen Sze Cho-Wing, Kalin Zhang Yanbo. , 18th Hong Kong International Cancer Congress to be held on 3 – 5 November, 2011. Cheung Kung Hai Conference Centre, Li Ka Shing Faculty of Medicine, The University of Hong Kong. Hong Kong.. 2011.
Zhang Y., Sze C.W. and Tong Y., Study on Mei Xing Su to improve Alzheimer’s disease. , Contract research. Funding from Orital Int’l Health Products Co., Ltd. (Hong Kong). Agreement code: RS100477. Project No. 20006390. . 2012.


Researcher : Zhang Z

Project Title:The Establishment of Neurobehavioral Experiments into the Acupuncture Course (BCHM3003, 針灸學) of Undergraduate Chinese Medicine Programs
Investigator(s):Zhang Z, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:07/2007


Project Title:The development of a clinical-case search system to introduce case-study learning mode into Chinese medical curricula
Investigator(s):Zhang Z, Wong HK
Department:School of Chinese Medicine
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:09/2008


Project Title:A single-blind, randomized, sham controlled study of electroacupuncture in accelerating the onset antidepressant action of selective serotonin reuptake inhibitors via serotonergic mechanisms
Investigator(s):Zhang Z, Sze CW
Department:School of Chinese Medicine
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:01/2009


Project Title:Central mechanisms involved in dense cranial electroacupuncture stimulation in treating major depression - a positron emission topographic (PET) study
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2010
Completion Date:04/2012


Project Title:A novel herbal preparation to treat antipsychotic-induced hyperprolactinemia in patients with schizophrenia: a randomized controlled study
Investigator(s):Zhang Z, Chen EYH
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2011
Completion Date:06/2012


Project Title:Multiple pharmacological mechanisms associated with effects of Peony-Glycyrrhiza Decoction (PGD), an herbal preparation, in suppressing hyperprolactinemia
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:The identification of central neural network for antidepressant effects of dense cranial electroacupuncture stimulation - a positron emission topographic (PET) study
Investigator(s):Zhang Z, Chung KF, Cowling BJ, Law ACK, Wong CS
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:The herbal medicine Peony-Glycyrrhiza Decoction (PGD) as an adjunctive therapy to treat antipsychotic-induced hyperprolactinemia in female patients with schizophrenia: a double-blind, randomized, placebo-controlled study
Investigator(s):Zhang Z, Chen EYH
Department:School of Chinese Medicine
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:02/2012


Project Title:The 5th International Society for Bipolar Disorders Conference Herbal medicine and acupuncture for bipolar disorders - randomized controlled trials
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:03/2012


List of Research Outputs

Fasmer O.B., Liao H., Huang Y., Berle J.Ø., Wu J., Oedegaard K.J., Wik G. and Zhang Z., A naturalistic study of the effect of acupuncture on heart-rate variability. , J Acupunct Meridian Stud . 2012, 5: 15-20.
Sze C.W., Ip C.W., Ng T.B., Zhang Y., Zhang Z., Cheung H.P., Cheng L.Y. and Tong Y., Compatibility of multiple herbal components in Erxian Decoction, a Chinese medicinal formula, for treating osteoporosis, European Journal of Integrative Medicine. 2012, 4: 187-196.
Sze C.W., Cheung H.P., Ng T.B., Zhang Z., Wong K.L., Wong H.K., Hu Y.M., Yow C.M. and Tong Y., Effects of Erxian decoction, a Chinese medicinal formulation, on serum lipid profile in a rat model of menopause, Chinese Medicine . 2011, 6: 40.
Wang D., Wong H.K., Zhang L., McAlonan G.M., Wang X.M., Sze C.W., Feng Y. and Zhang Z., Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemia, Progress in Neuro-Psychopharmacology & Biological Psychiatry . 2012, in press: n/a.
Yeung W.F., Chung K.F., Poon M.K., Ho Y.Y., Zhang Z., Zhang S.P., Ziea T.C. and Wong V.T., Chinese herbal medicine for insomnia: A systematic review of randomized controlled trials, Sleep Medicine Reviews. 2012, [Epub ahead of print].
Zhang Z., Ng R., Man M.S.C., Li T.Y.J., Wong W., Tan Q.R., Wong H.K., Chung K.F., Wong M.T., Tsang W.K.A., Yip K.C., Ziea E. and Wong V.C.W., Dense cranial electroacupuncture stimulation for major depressive disorder: a single-blind, randomized, controlled study, PloS ONE . 2012, 7: e29651.
Zhang Z., Chen Y.C., Wang H.N., Wang H.H., Xue Y.Y., Feng S.F. and Tan Q.R., Electroconvulsive therapy improves antipsychotic and somnographic responses in adolescents with first-episode psychosis – a case-controlled study, Schizophrenia Research . 2012, 137: 97-103.
Zhang Z., Wang X.M. and McAlonan G.M., Neural acupuncture unit: a new concept for interpreting effects and mechanisms of acupuncture., Evidence-based Complementary and Alternative Medicine. 2012, 2012: Article ID 429412.


Researcher : Zhao J

List of Research Outputs

Qi H., Zhao J., Han Y., Lau A.S.Y. and Rong J., Z-Ligustilide Potentiates the Cytotoxicity of Dopamine in Rat Dopaminergic PC12 Cells, Neurotoxicity Research . 2012.


Researcher : Zhao L

List of Research Outputs

Zhao L., 中藥藥對在瘙癢性皮膚病中的臨床應用探討, 第82屆國醫節暨2012年台北國際中醫藥學術論壇, 2012.


Researcher : Zheng G

List of Research Outputs

Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.
Li Y., Luo J., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y. and Shen J., Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent pathway, PLoS One. 2011, 6(8): 22901.
Zheng G., Wang X.T., Wang J.Z. and Shen J., 水通道蛋白-4在缺血/缺氧損傷后神經血管單元中的作用, 微循環學雜志, 2011, 2: 112-114.


Researcher : Zhong L

List of Research Outputs

Tong Y., Zhong L. and Feng Y., The Implementation of PBL in Chinese Medicine Program at The University of Hong Kong, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.
Zhong L., Tong Y., Tang G.W.K., Choi W.K. and Sze C.W., A Randomized Placebo-controlled trial on the effectiveness of a Chinese herbal formula to alleviate menopausal symptoms, The 10th Meeting of Consortium for Globalization of Chinese Medicine. 2011, 168.
Zhong L. and Tong Y., Can Chinese Herbal Medicine alleviate menopausal symptoms in Hong Kong Chinese Women? A pilot study on effects of a Chinese herbal formula on menopause. , The 14th World Congress on Controversies in Obstetrics, Gynecology and Infertility. 2011, 176.
Zhong L., Tong Y., Chen H., Cho W. and Meng X., The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: a systematic review and meta-analysis, Complementary Therapies in Medicine. 2012, 20: 240-252.
Zhong L., Tong Y. and Feng Y., The implementation of PBL in Chinese Medicine Program at the University of Hong Kong, The 10th Meeting of Consortium for Globalization of Chinese Medicine. 2011, 189.
Zhong L., 全國名老中醫專家陳湘君傳承工作室成員, 國家中醫藥管理局, 2012.
Zhong L. and Chen X., 上海市中醫藥科技進步一等獎, 2011.
Zhong L., 中醫扶正法治療強直性脊柱炎的優勢與特點, 2011.


Researcher : Zhu M

List of Research Outputs

Feng Y., Wang M.N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on bear bile and coptis. Handbook with programme 19, 8th world congress of Chinese Medicine. 2011.
Feng Y.G., Wang M.N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies . 2011.
Feng Y.G., Wang N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies (pp332-362). 2011.
Wang M.N., Pan W., Zhu M., Zhanf M., Hao X., Lian G. and Feng Y., Fangchinoline is a potential anti-cancer drug by inducing autophagic cell death in heaptocellular carcinoma cells, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.
Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, Journal of cellular biochemistry. 2011.
Zhu M., Wang M.N., Tsao G.S.W. and Feng Y., miR-21 and miR-23a were altered by Coptidis Rhizoma Aqueous Extract in Human Liver Cancer Cells, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.


Researcher : Zhu M

List of Research Outputs

Feng Y., Wang M.N., Zhu M., Chow O.Y., Ng K.M., Tong Y. and Tsao G.S.W., Comparative study on bear bile and coptis. Handbook with programme 19, 8th world congress of Chinese Medicine. 2011.
Feng Y.G., Wang M.N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies . 2011.
Feng Y.G., Wang N., Cheung F., Zhu M., Li H. and Feng Y., Molecular and Cellular Mechanism Studies on Anticancer Effects of Chinese Medicines, Chapter in Biomedical Engineering, Trends, Research and Technologies (pp332-362). 2011.
Wang M.N., Pan W., Zhu M., Zhanf M., Hao X., Lian G. and Feng Y., Fangchinoline is a potential anti-cancer drug by inducing autophagic cell death in heaptocellular carcinoma cells, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.
Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, Journal of cellular biochemistry. 2011.
Zhu M., Wang M.N., Tsao G.S.W. and Feng Y., miR-21 and miR-23a were altered by Coptidis Rhizoma Aqueous Extract in Human Liver Cancer Cells, 11th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM). 2011.


Researcher : Zhu W

List of Research Outputs

Gu Y., Zheng G., Xu M., Li Y., Chen X., Zhu W., Tong Y., Chung S.K., Liu K.J. and Shen J., Caveolin-1 regulates nitric oxide mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury, Journal of Neurochemistry. 2012, 120(1): 147-156.


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