DEPT OF SURGERY



Researcher : Au DKK

Project Title:Electrical tinnitus suppression in hearing-impaired patients
Investigator(s):Au DKK, Ho WK
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2003




Researcher : Chan ACY

List of Research Outputs

Chan A.C.Y. and Fan S.T., Caudate lobe resection, In: Chattopadhyay T.K., Sahni P. and Pal S. (eds.), GI Surgery. Annual Volume 18. Supplement on operatives procedures: Liver. Madras, Indian Association of Surgical Gastroenterology, 2011, 18: not known.
Chan A.C.Y., Common peroneal nerve palsy after liver transplantation (Rapid Communication), Journal of Liver. 2012, 1: 103.
Chan A.C.Y., Organising Committee Member, Hong Kong Surgical Forum - Summer, The University of Hong Kong, Hong Kong, 16 July 2011. 2011.
Chan A.C.Y., Recent advances in ERCP (Invited Lecture), Advances in Endoscopy 2012. Organized by the Departments of Surgery and Medicine, The University of Hong Kong, and Tung Wah Hospital. 2012.
Chan A.C.Y., Poon R.T.P., Cheung T.T., Chok K.S.H., Chan S.C., Fan S.T. and Lo C.M., Survival analysis of re-resection versus radiofrequency ablation for intrahepatic recurrence after hepatectomy for hepatocellular carcinoma, World Journal of Surgery. 2011, Epub on 2011-10-27.
Chan A.C.Y., Treatment strategy for recurrent hepatocellular carcinoma: repeated resection, salvage transplantation or radiofrequency ablation? (Oral Presentation), The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Chan S.C., Lo C.M., Chok K.S.H., Sharr W.W., Cheung T.T., Tsang S.H.Y., Chan A.C.Y. and Fan S.T., Modulation of graft vascular inflow guided by flowmetry and manometry in liver transplantation, Hepatobiliary & Pancreatic Diseases International. 2011, 10(6): 649-656.
Chan S.C., Fan S.T., Chok K.S.H., Cheung T.T., Chan A.C.Y., Fung J.Y.Y., Poon R.T.P. and Lo C.M., Survival advantage of primary liver transplantation for hepatocellular carcinoma within the up-to-7 criteria with microvascular invasion, Hepatology International. 2011, Epub on 2011-10-21.
Cheung T.T., Chan S.C., Chok K.S.H., Chan A.C.Y., Yu W.C., Poon R.T.P., Lo C.M. and Fan S.T., Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma, Hepatobiliary & Pancreatic Diseases International. 2012, 11(3): 267-271.
Cheung T.T., Chu F.S., Jenkins C.R., Tsang D.S., Chok K.S.H., Chan A.C.Y., Yau T.C.C., Chan S.C., Poon R.T.P., Lo C.M. and Fan S.T., Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma, World Journal of Surgery. 2012, Epub on 2012-06-15.
Chiu J., Tang Y.F., Yao T.J., Wong A., Wong H., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Fan S.T., Poon R.T.P. and Yau T.C.C., The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: A retrospective analysis of efficacy, safety, and survival benefits, Cancer. 2012, Epub on 2012-04-19.
Chok K.S.H., Fung J.Y.Y., Chan S.C., Cheung T.T., Sharr W.W., Chan A.C.Y., Fan S.T. and Lo C.M., Outcomes of living donor liver transplantation for patients with preoperative type 1 hepatorenal syndrome and acute hepatic decompensation, Liver Transplantation. 2012, Epub on 2012-01-30.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Fung J.Y.Y., Tsang S.H.Y., Fan S.T. and Lo C.M., Single-centre experience of liver transplantation for familial amyloidotic polyneuropathy of non-Val30Met variants in Chinese patients, Amyloid. 2012, 19(1): 33-36.
Dai W.C., Fan S.T., Cheung T.T., Chok K.S.H., Chan A.C.Y., Tsang S.H.Y., Poon R.T.P. and Lo C.M., The impact of family history of hepatocellular carcinoma on its patients' survival, Hepatobiliary & Pancreatic Diseases International. 2012, 11(2): 160-164.
Fung J.Y.Y., Chan S.C., Cheung C.K.Y., Chok K.S.H., Sharr W.W., Chan A.C.Y., Dai W.C., Cheung T.T., Fan S.T., Lai C.L., Yuen R.M.F. and Lo C.M., Entecavir Versus Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B., 18th Annual International Congress on ILTS Location: San Francisco, USA. May 16-19, 2012. Liver Transplantation.. 2012, 18 (supp 1): S124.
Fung J.Y.Y., Cheung C.K.Y., Chan S.C., Yuen R.M.F., Chok K.S.H., Sharr W.W., Dai W.C., Chan A.C.Y., Cheung T.T., Tsang S.H.Y., Lam B.K.Y., Lai C.L. and Lo C.M., Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation, Gastroenterology. 2011, 141(4): 1212-1219.
Poon R.T.P., Chan P., Tai K.S., Cheung T.T., Chan A.C.Y., Kowk P.C., Jin K., Lee K.F. and Lap P.B., A multi-center phase II trial of Bevacizumab (B) pre- and post-transarterial chemoembolization (TACE) treatment for patients with localized rnresectable HCC: interim safety analyses, Best Abstract Award, Round Asia Oncology Forum, Chinese Society of Clinical Oncology, Shanghai, China . 2011.
Wong H., Tang Y.F., Yao T., Chiu J., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Poon R.T.P., Fan S.T. and Yau T.C.C., The outcomes and safety of single-agent sorafenib in the treatment of elderly patients with advanced hepatocellular carcinoma (HCC), Oncologist. 2011, 16(12): 1721-1728.


Researcher : Chan JYK

List of Research Outputs

Yau W.L., Pang R.W.C., Lee K.W., Lam C.S.C., Wo Y.H., Ng L., Chan J.Y.K., Chow A.K.M., Ng K.T.P., Man K. and Poon R.T.P., Overexpression of miR106b promotes metastasis in hepatocellular carcinoma by activating epithelial mesenchymal transition process, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.


Researcher : Chan KL

List of Research Outputs

Chan K.L., Member of Editorial Board, Global Journal of Surgery. 2011.
Chan K.L., Member of Editorial Board, World Journal of Clinical Pediatrics. 2011.
Chan K.L., Chung H.Y., Chan S.C. and Tam P.K.H., Timely liver transplantation is essential for the survival of paediatric patients with hepatopulmonary syndrome, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Chung H.Y., Chan K.L., Chan I.H.Y., Ng I.O.L., Chan G.C.F., Chan S.C. and Tam P.K.H., Clinical experience in managing post transplant lymphoproliferative disease (PTLD) in paediatric patients after liver transplant, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Sung W.K., Zheng H., Li S., Chen R., Liu X., Li Y., Lee N.P.Y., Lee W.H., Wong K.F., Liu A.M.L., Poon R.T.P., Fan S.T., Chan K.L. and Luk J.M.C., Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma, Nature Genetics. 2012, 44(7): 765-769.


Researcher : Chan SC

List of Research Outputs

Au W.Y. and Chan S.C., Association between glucose 6-phosphate dehydrogenase (G6PD) deficiency and fatal outcome of hepatitis E infection in middle-aged men (Letter to the Editor), Singapore Medical Journal. 2012, 53(2): 148-149.
Chan A.C.Y., Poon R.T.P., Cheung T.T., Chok K.S.H., Chan S.C., Fan S.T. and Lo C.M., Survival analysis of re-resection versus radiofrequency ablation for intrahepatic recurrence after hepatectomy for hepatocellular carcinoma, World Journal of Surgery. 2011, Epub on 2011-10-27.
Chan K.L., Chung H.Y., Chan S.C. and Tam P.K.H., Timely liver transplantation is essential for the survival of paediatric patients with hepatopulmonary syndrome, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Chan S.C., Bioethical challenges of liver transplantation (Invited Lecture), The 2nd Cross Strait Transplant Forum. Mongolia, China, 6 August 2011. 2011.
Chan S.C., Convenor, Two Decades of Liver Transplantation in Hong Kong, Hong Kong, 8 October 2011. 2011.
Chan S.C., Donor right hepatectomy – How we do it in Hong Kong (Invited Lecture), Seoul National University Hospital. Living Donor Liver Transplantation Live Surgery Symposium, Seoul, Korea, 29 September 2011. 2011.
Chan S.C., General principles of organ transplantation (Course Lecturer), Preparatory Course for Exit Examination for Candidates of the Hong Kong College of Surgeons, 20 February 2012. 2012.
Chan S.C. and Fan S.T., Hepatic resection for living donor transplantation, In: Jarnagin W.R. (ed.), Blumgart's Surgery of the Liver, Biliary Tract, and Pancreas, 5th edition. Philadelphia, Elsevier Saunders, 2012, 2: 1520-1528.
Chan S.C., Liver transplant for paediatric oncology patient (Course Lecturer), Paediatric Haematology & Oncology Nursing Course organized by Institute of Advanced Nursing Studies, Hospital Authority, Hong Kong, 4 October 2011. 2011.
Chan S.C., Liver transplantation for hepatitis b patients (Invited Lecture), The 7th International Symposium on Viral Hepatitis and Liver Diseases, Shanghai, China, 25 June 2012. 2012.
Chan S.C., Management of chronic hepatitis B before and after liver transplantation (Invited Lecture), BMS Satellite Symposium in GEST Spring Convention - Contemporary Issues in CHB Management, Taipei, Taiwan, 23 March 2012. 2012.
Chan S.C., Member of Editorial Board, Hepatobiliary & Pancreatic Diseases International. 2012.
Chan S.C., Member of Editorial Board, World Journal of Transplantation. 2012.
Chan S.C., Member of Scientific Committee, Asian-Pacific Hepato-Pancreato-Biliary Association. 2012.
Chan S.C., Lo C.M., Chok K.S.H., Sharr W.W., Cheung T.T., Tsang S.H.Y., Chan A.C.Y. and Fan S.T., Modulation of graft vascular inflow guided by flowmetry and manometry in liver transplantation, Hepatobiliary & Pancreatic Diseases International. 2011, 10(6): 649-656.
Chan S.C., Outcome of right liver living donor liver transplantation (Invited Lecture), “Challenges and Advances in Colorectal and Hepatic Surgery” - Korean Surgical International Symposium 2011 cum Annual Meeting of Korean Surgical Association, Seoul, Korea, 25-26 November 2011. 2011.
Chan S.C., Fan S.T. and Wong J., Recurrent pyogenic cholangitis, In: Jarnagin W.R. (ed.), Blumgart’s Surgery of the Liver, Biliary Tract, and Pancreas, 5th edition. Philadelphia, Elsevier Saunders, 2012, 1: 680-696.
Chan S.C., Right liver graft implantation (Invited Lecture), Seoul National University Hospital. Living Donor Liver Transplantation Live Surgery Symposium, Seoul, Korea, 29 September 2011 . 2011.
Chan S.C., Right liver living donor liver transplantation (Invited Lecture), The 12th Congress of the Asian Society of Transplantation, Seoul, Korea, 25-28 September 2011. 2011.
Chan S.C., Role of liver transplant in hepatocellular carcinoma (Invited Lecture), Fortis International Liver Summit - Understanding Liver Disease Mechanisms and Advances in Adult and Children, Chandigarh, India, 8-10 March 2012. 2012.
Chan S.C., Segmental approach in liver resection in normal and diseased liver (Invited Lecture), Fortis International Liver Summit - Understanding Liver Disease Mechanisms and Advances in Adult and Children, Chandigarh, India, 8-10 March 2012. 2012.
Chan S.C., Simplifying and tailoring liver transplantation (Invited Lecture), Department of Surgery, Queen Mary Hospital, The University of Hong Kong. Seminar, 12 July 2011. 2011.
Chan S.C., Specialist Expert, Hong Kong Academy of Medicine. Specialty: Liver Transplantation, Hepatobiliary & Pancreatic Surgery. 2012.
Chan S.C., Start writing radomized controlled trial (Course Lecturer), Course for Resident organized by Hong Kong College of Surgeons, 24 February 2012. 2012.
Chan S.C., Surgical options for treatment of hepatocellular carcinoma (Invited Lecture), Kobe University, Kobe, Japan, 16 April 2012. 2012.
Chan S.C., Fan S.T., Chok K.S.H., Cheung T.T., Chan A.C.Y., Fung J.Y.Y., Poon R.T.P. and Lo C.M., Survival advantage of primary liver transplantation for hepatocellular carcinoma within the up-to-7 criteria with microvascular invasion, Hepatology International. 2011, Epub on 2011-10-21.
Chan S.C., Vice President, Hong Kong Society of Transplantation. 2011.
Chan S.C., Visiting Fellow, Liver Transplantation Center, University of California, Los Angeles, USA, 10 October - 16 November 2011. 2011.
Cheung T.T., Chan S.C., Chok K.S.H., Chan A.C.Y., Yu W.C., Poon R.T.P., Lo C.M. and Fan S.T., Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma, Hepatobiliary & Pancreatic Diseases International. 2012, 11(3): 267-271.
Cheung T.T., Chu F.S., Jenkins C.R., Tsang D.S., Chok K.S.H., Chan A.C.Y., Yau T.C.C., Chan S.C., Poon R.T.P., Lo C.M. and Fan S.T., Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma, World Journal of Surgery. 2012, Epub on 2012-06-15.
Chok K.S.H., Fung J.Y.Y., Chan S.C., Cheung T.T., Sharr W.W., Chan A.C.Y., Fan S.T. and Lo C.M., Outcomes of living donor liver transplantation for patients with preoperative type 1 hepatorenal syndrome and acute hepatic decompensation, Liver Transplantation. 2012, Epub on 2012-01-30.
Chok K.S.H., Chan S.C., Poon R.T.P., Fan S.T. and Lo C.M., Re-resection for metachronous primary hepatocellular carcinoma: is it justified?, ANZ Journal of Surgery. 2012, 82(1-2): 63-67.
Chung H.Y., Chan K.L., Chan I.H.Y., Ng I.O.L., Chan G.C.F., Chan S.C. and Tam P.K.H., Clinical experience in managing post transplant lymphoproliferative disease (PTLD) in paediatric patients after liver transplant, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Fung J.Y.Y., Tsang S.H.Y., Fan S.T. and Lo C.M., Single-centre experience of liver transplantation for familial amyloidotic polyneuropathy of non-Val30Met variants in Chinese patients, Amyloid. 2012, 19(1): 33-36.
Fung J.Y.Y., Chan S.C., Cheung C.K.Y., Chok K.S.H., Sharr W.W., Chan A.C.Y., Dai W.C., Cheung T.T., Fan S.T., Lai C.L., Yuen R.M.F. and Lo C.M., Entecavir Versus Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B., 18th Annual International Congress on ILTS Location: San Francisco, USA. May 16-19, 2012. Liver Transplantation.. 2012, 18 (supp 1): S124.
Fung J.Y.Y., Cheung C.K.Y., Chan S.C., Yuen R.M.F., Chok K.S.H., Sharr W.W., Dai W.C., Chan A.C.Y., Cheung T.T., Tsang S.H.Y., Lam B.K.Y., Lai C.L. and Lo C.M., Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation, Gastroenterology. 2011, 141(4): 1212-1219.
Fung J.Y.Y., Chan S.C., Yuen R.M.F., Lai C.L., Chok K.S.H., Sharr W.W., Dai W.C., Fan S.T. and Lo C.M., Long-term Outcome of Lamivudine Mono-prophylaxis After Liver Transplantation In Hepatitis B Patients , 62nd Annual Meeting Of The American-association-for-the-study-of-liver-diseases (AASLD) Location: San Francisco, USA. November 04-08, 2011. Hepatology . 2011, 54(Supp 1): 450A-450A.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Man K., Wong N., Li C., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, Young Investigator Award, the 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012. 2012.
Siriwardana R.C., Chan S.C., Chok K.S.H., Lo C.M. and Fan S.T., Effects of the liver volume and donor steatosis on errors in the estimated standard liver volume, Liver Transplantation. 2011, 17(12): 1437-1442.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.


Researcher : Chan SY

List of Research Outputs

Chan S.Y., Advanced upper GI endoscopic procedures, Advances in Endoscopy 2012, Departments of Surgery and Medicine, Queen Mary Hospital and Tung Wah Hospital, 24 March 2012. 2012.
Chan S.Y., Laparoscopic distal gastrectomy for teapot stomach, Hong Kong Surgical Forum - Summer, The University of Hong Kong, Hong Kong, 16 July 2011. 2011.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., Extra Free Paper Session: What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer? (Abstract), Annual Scientific Meeting 2011, The College of Surgeons of Hong Kong and Macau Surgical Association, Hong Kong, 17 - 18 September 2011.
Tong D.K.H., Law S.Y.K. and Chan S.Y., Operative outcomes of colonic interposition in the treatment of esophageal cancer: a three decades experience (Abstract), Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Tong D.K.H., Law S.Y.K. and Chan S.Y., Robotic-assisted esophageal epiphrenic diverticulectomy, myotomy and Dor Hemi-Fundoplication (Video Abstract), Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, Session on "ISDS Free Papers, Esophagus 1: Malignant", (Abstract), The International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer?, Surgical Practice. 2011, 15(Suppl 2): B7.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, World Journal of Surgery. 2011, 35(Suppl 1): S172.


Researcher : Chan WYL

List of Research Outputs

Yau T.C.C., Cheng P.N., Chan P., Chan W.Y.L., Chen L., Yuen J., Pang R.W.C., Fan S.T. and Poon R.T.P., A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma, Investigational New Drugs. 2012, Epub on 2012-03-17.


Researcher : Chan YC

Project Title:SERUM MATRIX METALLOPROTEINASES (MMPS) AS PROGNOSITIC INDICATOR FOR THORACIC AORTIC DISEASE
Investigator(s):Chan YC, Cheuk LY
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2009


List of Research Outputs

Chan Y.C., Advances in endovascular treatment (Invited Chairman), Hong Kong Surgical Forum - Winter, The University of Hong Kong, Hong Kong, 14 January 2012. 2012.
Chan Y.C., Carotid surgery for stroke prevention, 第四届上海颈动脉与脑卒中国际论坛, 上海, 中国, 9-11 October 2011. 2011.
Chan Y.C., Contemporary management of aortic dissection: mindful of the unknown, The 17th International Surgical Symposium, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, 5 November 2011. 2011.
Chan Y.C. and Cheng S.W.K., Does difficult iliac access still exit? (Cover Story), Endovascular Today. 2012, 11(3): 83-87.
Chan Y.C., Helical interwoven nitinol stents for femoropopliteal disease, Hong Kong Surgical Forum - Winter, The University of Hong Kong, Hong Kong, 14 January 2012. 2012.
Chan Y.C., Clough R.E. and Taylor P.R., Predicting aneurysmal dilatation after type B aortic dissection (Editorial), European Journal of Vascular and Endovascular Surgery. 2011, 42(2): 464-466.
Chan Y.C., Ting A.C.W., Yiu W.K. and Cheng S.W.K., Successful emergency endovascular treatment of juxtarenal and infrarental mycotic aortic aneurysms in patients with small diameter aortae using Cook Zenith ESLE stentgrafts, World Journal of Emergency Medicine. 2012, 3(2): 146-149.
Chan Y.C., Vascular and Endovascular Surgery at University of Hong Kong (Invited Speaker), UCLA Travel Fellowship, UCLA Gonda (Goldschmied) Vascular Center, David Geffen School of Medicine, University of California, Los Angeles, USA, March 2012. 2012.
Cheuk L.Y., Chan Y.C. and Cheng S.W.K., Changes in inflammatory response after endovascular treatment for type B aortic dissection, PLoS One. 2012, 7(5): e37389.
Chua G.T., Chan Y.C. and Cheng S.W.K., Vitamin D status and peripheral arterial disease: evidence so far (Review), Journal of Vascular Health and Risk Management. 2011, 7: 671-675.
Wylie S.J., Wong G.T.C., Chan Y.C. and Irwin M.G., Endovascular aneurysm repair: a perioperative perspective, Acta Anaesthesiologica Scandinavica. 2012, 56: 941-9.
Yiu W.K., Chan Y.C., Ting A.C.W. and Cheng S.W.K., Para-aortic lymphoma mimicking mycotic abdominal aortic aneurysm: case presentation & review of literature (Poster Presentation), The 12th Annual Congress of the Asian Society for Vascular Surgery (ASVS) and 6th Asian Venous Forum, Taipei, Taiwan, 29 September to 2 October 2011.


Researcher : Chan YW

Project Title:Curcumin suppresses nasopharyngeal carcinoma cell migration through activation of E-cadherin
Investigator(s):Chan YW, Wong STS
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2010


Project Title:Quantitative analysis of Epstein-Barr virus-encoded microRNA BART7 in recurrent nasopharyngeal carcinoma patients
Investigator(s):Chan YW, Wong STS
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2012


List of Research Outputs

Chan C.L.R., Liu H.L. and Chan Y.W., Free-flap harvesting from paralytic limbs of poliomyelitis patients - a safe and feasible option, Journal of Plastic, Reconstructive and Aesthetic Surgery. 2011, Epub on 30 November 2011.
Chan Y.W., Advisor, Pan-Asia Academy of Facial Plastic and Reconstructive Surgery. 2011.
Chan Y.W., Ng W.M. and Wei W.I., Anatomical study and clinical applications of free posterior tibial flap in the Head and Neck region, Plastic and Reconstructive Surgery. 2011, 128(3): 131e-139e.
Chan Y.W., Anatomical study and clinical applications of the free posterior tibial flap in the head and neck region, The 5th European Conference On Head & Neck Oncology, Poznan, Poland 18 – 21 April 2012.
Chan Y.W., Breast reconstruction: Hong Kong experience, Pan-Asia Academy of Facial Plastic and Reconstructive Surgery, Chengdu, China, 18 - 20 August 2011. 2011.
Chan Y.W. and Wei W.I., Clinical application of the free posterior tibial flap in the oral cavity, The 3rd World Congress of the International Academy of Oral Oncology (IAOO) – Yin and Yang: Balancing Cure and Consequences, Singapore, 14 – 17 July 2011.
Chan Y.W., Council Member (December 2011 – Present), The Hong Kong Society of Plastic, Reconstructive and Aesthetic Surgery. 2012.
Chan Y.W., Council Member (June 2011 – present) , American Academy of Otolaryngology, Head & Neck Surgery. 2011.
Chan Y.W. and Wei W.I., Critical appraisal of maxillary swing approach for nasopharyngeal carcinoma, Expert Opinion on Therapeutic Targets. 2012, 16(S1): S111-S117.
Chan Y.W., Critical appraisal of maxillary swing approach for nasopharyngeal carcinoma, The 5th European Conference On Head & Neck Oncology, Poznan, Poland 18 – 21 April 2012.
Chan Y.W. and Wei W.I., Current management strategy of hypopharyngeal carcinoma, Auris Nasus Larynx. 2012, Epub ahead of print.
Chan Y.W., Lee V.H.F., Chow V.L.Y., To V.S.H. and Wei W.I., Extracapsular lymph node spread in recurrent nasopharyngeal carcinoma, Laryngoscope. 2011, 121(12): 2576-2580.
Chan Y.W., To V.S.H. and Wei W.I., Extracapular lymph node spread in recurrent nasopharyngeal carcinoma, Laryngoscope. 2011, 12(1): 2576-2580.
Chan Y.W., Li G.K.H., Chung H.P. and Chow V.L.Y., Extramammary Paget's disease: 20 years of experience in Chinese population, International Journal of Surgical Oncology. 2012, Epub ahead of print.
Chan Y.W., Flaps for reconstruction of facial defects, Advances in Facial Plastic Surgery and Rhinology, Hong Kong, 7 - 9 December 2011. 2011.
Chan Y.W., Head and Neck Reconstruction: what can be achieved, The College of Surgeons of Hong Kong / Macau Surgical Association Annual Scientific Meeting, Reconstructive Surgery in Focus, Hong Kong, 17 - 18 September 2011. 2011.
Chan Y.W., Honorary Advisor (February 2010 – present), Kin Lok Club, Hong Kong (Nasopharyngeal carcinoma patient support group). 2011.
Chan Y.W., Management of complications after laryngo-pharyngectomy, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
Chan Y.W., Management of recurrent laryngo-pharyngeal cancer, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
Chan Y.W. and Wei W.I., Nasopharyngectomy for locally advanced recurrent nasopharyngeal carcinoma: is there a limit?, The 3rd World Congress of the International Academy of Oral Oncology (IAOO) – Yin and Yang: Balancing Cure and Consequences, Singapore, 14 – 17 July 2011.
Chan Y.W., Chow V.L.Y., Chan C.L.R. and Lau G.I.S.K., Oncological outcome after free jejunal flap reconstruction for carcinoma of the hypopharynx, European Archives of Oto-Rhino-Laryngology. 2011, Epub on 18 November 2011.
Chan Y.W., Optimizing the result of reconstruction of circumferential pharyngeal defects after tumor resection, The 5th European Conference on Head & Neck Oncology, Poznan, Poland, 18 - 21 April 2012.
Chan Y.W., Palliation for advanced malignancy in the oral cavity, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
Chan Y.W., Palliative surgery for advanced tumour of the oral cavity, The 3rd World Congress of the International Academy of Oral Oncology (IAOO) – Yin and Yang: Balancing Cure and Consequences, Singapore, 14 – 17 July 2011.
Chan Y.W., Pharyngectomy: how much to resect?, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
Chan Y.W., Prediction of surgical outcome using plasma Epstein-Barr virus DNA and FDG PET scan in recurrent nasopharyngeal carcinoma, The 5th European Conference On Head & Neck Oncology, Poznan, Poland 18 – 21 April 2012.
Chan Y.W., President (April 2012 – April 2013), The Hong Kong Head & Neck Society. 2012.
Chan Y.W., To V.S.H., Wong S.T.S. and Wei W.I., Quality of dying in head and neck cancer patients: the role of surgical palliation, European Archives of Oto-Rhin-Laryngology. 2012, Epub on 5 June 2012.
Chan Y.W., Chow V.L.Y. and Wei W.I., Quality of life of patients after salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma, Cancer. 2011, 118(15): 3710-3718.
Chan Y.W., Reconstruction after laryngo-pharyngectomy, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
Chan Y.W., Reconstruction after major resection, Plastic Surgery Symposium - Refining your face, Hong Kong, 12 November 2011. 2011.
Chan Y.W. and Wei W.I., Recurrent nasopharyngeal carcinoma after salvage nasopharyngectomy, Archives of Otolaryngology-Head and Neck Surgery. 2012, 138(6): 572-576.
Chan Y.W., Reviewer, Asian Journal of Surgery. 2011.
Chan Y.W., Reviewer, British Journal of Dermatology. 2011.
Chan Y.W., Reviewer, Journal of Plastic, Reconstructive and Aesthetic Surgery. 2011.
Chan Y.W., Reviewer, Journal of Radiation Oncology. 2011.
Chan Y.W., Reviewer, Laryngoscope. 2011.
Chan Y.W., Reviewer, Plastic and Reconstructive Surgery. 2011.
Chan Y.W., Salvage surgery for nasopharyngeal carcinoma (Invited Lecture), Tri-Society Head & Neck Oncology Meeting 2011, Singapore, 1 - 3 September 2011. 2011.
Chan Y.W., Surgery for recurrent tumour of the oral cavity, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
Chan Y.W., Vascular and pigmented lesions and their management, Plastic Surgery Symposium “Refining your face”, Hong Kong, 12 November 2011. 2011.
Chan Y.W., Volume Editor, Head and Neck Clinics – Nasopharyngeal carcinoma. 2011.
Chow V.L.Y., Chan Y.W., Chan R.C., Chung H.P. and Wei W.I., Basal cell carcinoma of the head and neck region in ethnic Chinese, International Journal of Surgical Oncology. 2011, Epub on 14 September 2011.
Chung J.C.K., Tsang R.K.Y., To V.S.H., Ho C.W.A., Chan Y.W., Ho W.K. and Wei W.I., Secondary head and neck cancer in patients with history of haematological malignancy, Head & Neck. 2012, Epub on 15 May 2012.
Gao W., Chan Y.W., Wei W.I. and Wong S.T.S., Anti-Cancer effects of curcumin on head and neck cancer, Anticancer Agents in Medical Chemistry. 2012, Epub on 2 May 2012.
Gao W., Li J.Z., Ho W.K., Chan Y.W. and Wong S.T.S., Biomarkers for use in monitoring responses of nasopharyngeal carcinoma cells to Ionizing radiation, Sensors. 2012, 12(7): 8832-8846.
Lau G.S.K., Chan Y.W. and Wei W.I., Role of surgery in the treatment of radiation-induced sarcomas of the head and neck, Journal of Cell Science and Therapy. 2011, S2:002.
Lee V.H.F. and Chan Y.W., Chemoradiation for recurrent head and neck cancers in Head and Neck Course, Department of Surgery, The University of Hong Kong, Head and Neck Course, Department of Surgery, The University of Hong Kong. The University of Hong Kong, 2012.
To V.S.H., Chan Y.W., Tsang R.K.Y. and Wei W.I., Review of salivary gland neoplasms, ISRN Otolaryngology. 2012, 2012.
Tsang R.K.Y., Tang W.Y., Gao W., Ho W.K., Chan Y.W., Wei W.I. and Wong S.T.S., Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10, Cancer Investigation. 2012, 30(7): 503-512.
Wong S.T.S., Gao W., Li Z., Chan Y.W. and Ho W.K., Epigenetic dysregulation in laryngeal squamous cell carcinoma, Journal of Oncology. 2012, 2012: 739461.
Wong S.T.S., Gao W., Ho W.K., Chan Y.W. and Tsang R.K.Y., MicroRNA dysregulation in squamous cell carcinoma of head and neck, In: Li X. (ed.), Squamous Cell Carcinoma. Rijeka, Croatia, Intech, 2011, 255-280.


Researcher : Chau WW

List of Research Outputs

Kwong A., Mang O.W., Wong H.N., Chau W.W., Law S.C. and Hong Kong Breast Cancer Research Group , Breast cancer in Hong Kong, Southern China: the first population-based analysis of epidemiological characteristics, stage-specific, cancer-specific, and disease-free survival in breast cancer patients: 1997-2001, Annals of Surgical Oncology. 2011, 18(11): 3072-3078.


Researcher : Chen Y

List of Research Outputs

Chan Y.K., Kirjavainen P., Chen Y. and El-Nezamy H.S., Atherosclerosis and gut microbiota: A potential target for probiotics, In: Seppo Salminen, Atte von Wright and Arthur Ouwehand, Lactic Acid Bacteria: Microbiological and Functional Aspects. CRC Press, 2012, 331-342.
Chan Y.K., Kirjavainen P.V., Chen Y. and El-Nezamy H.S., Probiotics and Atherosclerosis – a New Challenge? , FFF Probiotics 2012, an International Symposium on Probiotics, Prebiotics and Health . 2012.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Partanen H.A., Vahakangas K.H., Woo C.S.J., Auriola S., Veid J., Chen Y., Myllynen P. and El-Nezamy H.S., Transplacental transfer of melamine, Placenta. 2012, 33: 60-66.
Peng J., Chan K.Y., Chen Y., Lamb J.R., Tam P.K.H. and El-Nezamy H.S., Effects of water uptake on melamine renal stone formation in mice, Nephrol Dial Transplant . 2012, 27: 2225-2231.
Peng J., Li D., Chan Y.K., Chen Y., Lamb J.R., Tam P.K.H. and El-Nezamy H.S., Effects of water uptake on melamine renal stone formation in mice, Nephrology Dialysis Transplantation. 2012, 27: 2225-2231.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
Tsang J.Y.S., Ratnasothy K., Li D., Chen Y., Bucy R.P., Lau K.F., Smyth L., Lombardi G., Lechler R. and Tam P.K.H., The potency of allospecific tregs cells appears to correlate with T cell receptor functional avidity, American Journal of Transplantation. 2011, 11(8): 1610-1620.


Researcher : Cheng CKC

List of Research Outputs

Cheung P.F.Y., Yip C.W., Wong C.L., Cheng C.K.C., Wong Y.L. and Cheung S.T., Characterization of GEP-expressing cells in human primary hepatocellular carcinoma (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Cheung P.F.Y., Cheng C.K.C., Wong C.L., Ho J.C.Y., Yip C.W., Lui V.C.H., Cheung A.N.Y., Fan S.T. and Cheung S.T., Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells, PLoS One. 2011, 6(12): e28246.
Cheung S.T., Cheung P.F.Y., Cheng C.K.C. and Fan S.T., Genomics approach to identify drug transporter ABCF1 associated with liver cancer recurrence and chemo-resistance (Abstract), The Annual Meeting of the American Association for Cancer Research, Chicago, USA, 31 March - 4 April 2012.
Cheung S.T., Cheung P.F.Y., Cheng C.K.C. and Fan S.T., Genomics approach to identify growth factor and drug transporter associated with liver cancer recurrence and chemo-resistance (Abstract), The 22nd Congress of the Asian Pacific Association for the Study of the Liver, Taipei, Taiwan, 16-19 February 2012.
Lam C.Y., Yip C.W., Poon T.C.W., Cheng C.K.C., Ng E.W.Y., Wong C.L., Cheung P.F.Y., Lai P.B.S., Ng I.O.L., Fan S.T. and Cheung S.T., Identification and characterization of tropomyosin 3 associated with granulin-epithelin precursor in human hepatocellular carcinoma, PLoS One. 2012, 7(7): e40324.


Researcher : Cheng G

List of Research Outputs

So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.


Researcher : Cheng LC

List of Research Outputs

Lam C.L.D., Girard L., Beer D.G., Gerald W.L., Kris M., Sihoe A.D.L., Cheng L.C., Wong M.P., Chung L.P., Ip M.S.M., Lam W.K., Gazdar A.F., Wistuba I.I. and Minna J.D., Expression of LATS2 and STK17B distinguishes epidermal growth factor receptor (EGFR) gene mutations in exons 19 and 21 from those in 18 and 20 in lung adenocarcinomas, World Congress of Lung Cancer 2011.
Zhang Y., Wu W., Sun H., Deng X.L., Cheng L.C., Li X., Tse H.F., Lau C.P. and Li G.R., Modulation of human cardiac transient outward potassium current by EGFR tyrosine kinase and Src-family kinases, Cardiovasc Res.. 2012, 93(3): 424-33.


Researcher : Cheng Q

List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.


Researcher : Cheng SWK

Project Title:Endovascular program for treating thoracic aortic dissections
Investigator(s):Cheng SWK, Ting ACW
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2004


Project Title:Endovascular aortic stent graft program for treating acute aortic dissections
Investigator(s):Cheng SWK, Ting ACW
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2007


Project Title:Percutaneous plaque excision for lower limb salvage in peripheral arterial occlusive disease
Investigator(s):Cheng SWK, Ting ACW, Chan YC
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:12/2007


Project Title:Endovascular aortic stent graft program – a minimally invasive standard for treating aortic disease
Investigator(s):Cheng SWK, Ting ACW, Chan YC
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/2010


Project Title:MicroRNAs profiling in aortas from Abdominal Aortic Aneurysms (AAAs) patients
Investigator(s):Cheng SWK, Cheuk LY
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2011


Project Title:Study of the pathological role of the specific S1P3 receptor in Abdominal Aortic Aneurysms (AAAs) and its relationship to Cyclooxygenase-2 (COX-2) pathway.
Investigator(s):Cheng SWK
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2012


Project Title:Endovascular aortic stent graft program for treating aortic dissections
Investigator(s):Cheng SWK, Chan YC
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:03/2012


List of Research Outputs

Chan Y.C. and Cheng S.W.K., Does difficult iliac access still exit? (Cover Story), Endovascular Today. 2012, 11(3): 83-87.
Chan Y.C., Ting A.C.W., Yiu W.K. and Cheng S.W.K., Successful emergency endovascular treatment of juxtarenal and infrarental mycotic aortic aneurysms in patients with small diameter aortae using Cook Zenith ESLE stentgrafts, World Journal of Emergency Medicine. 2012, 3(2): 146-149.
Cheng S.W.K., Qing K. and Yiu W.K., A morphologic study of chronic type B aortic dissections and aneurysms after thoracic endovascular stent grafting, The 26th Annual Meeting of the Western Vascular Society, Kauai, Hawaii, 17-20 September 2011.
Cheng S.W.K., Advanced management and development for EVAR and TEVAR, International Endovascular Advance (IEVA) 2011 and the 4th Annual Meeting and Scientific Congress of Taiwan Society for Vascular Surgery, Nantou, Taiwan, 23 - 25 September 2011. 2011.
Cheng S.W.K., Anatomical issues in the Asian patient, Aortic Asia Bali 2012, The Laguna, Nusa Dua, Bali, 7-8 March 2012. 2012.
Cheng S.W.K., Aortic aneurysm care in the 21st century (Plenary I) (Invited Chairman), Aortic Asia Bali 2012, Bali, Indonesia, 7-8 March 2012. 2012.
Cheng S.W.K., Aortic repair: recent advance and future development (Pre-opening Ceremony Lecture), The 12th Annual Congress of Asian Society for Vascular Surgery (ASVS) and the 6th Asian Venous Forum, Taipei, Taiwan, 29 September - 2 October 2011. 2011.
Cheng S.W.K., Aortic: modern management (Invited Co-moderator), 2012 Pacific Northwest Endovascular Conference, Seattle, USA, 24 May 2012. 2012.
Cheng S.W.K., Associated Editor of International Editorial Board (2008 - present), Annals of Vascular Diseases. 2012.
Cheng S.W.K., Biomechanical remodeling and device charastistic (Invited Co-moderator), International Endovascular Advance (IEVA) 2011 & the 4th Annual Meeting and Scientific Congress of Taiwan Society for Vascular Surgery, Nantou, Taiwan, 23-25 September 2011. 2011.
Cheng S.W.K., Case demo 58: Thoracoabdominal aorta aneurysm (Invited Demonstrator), China Endovascular Course 2011, Beijing, China, 3-6 November 2011. 2011.
Cheng S.W.K., Challenges in vascular surgery (Invited Chairman), Hong Kong Surgical Forum - Winter, The University of Hong Kong, Hong Kong, 14 January 2012. 2012.
Cheng S.W.K., Council Member (2004 - present), The College of Surgeons of Hong Kong. 2012.
Cheng S.W.K., Crossing challenging chronic total occlusions - through or around? (Invited Co-moderator), LINC Asia-Pacific Hong Kong 2012, Hong Kong, 1-3 February 2012. 2012.
Cheng S.W.K., Current advances in fenestrated and branched endografts, Hong Kong Surgical Forum - Winter, The University of Hong Kong, Hong Kong, 14 January 2012. 2012.
Cheng S.W.K., Enhanced accuracy and durability for expanded indications for EVAR with Zenith fenestrated endografts (Cook Lunch Symposium Cook pavilion), International Endovascular Advance (IEVA) 2011 and the 4th Annual Meeting and Scientific Congress of Taiwan Society for Vascular Surgery, Nantou, Taiwan, 23 - 25 September 2011. 2011.
Cheng S.W.K., Evolution of aortic endovascular therapy in Asia Pacific, Aortic Asia Bali 2012, The Laguna, Nusa Dua, Bali, 7-8 March 2012. 2012.
Cheng S.W.K., Fenestrated and branched grafts offer an ideal approach for TAAA repair, International Endovascular Advance (IEVA) 2011 and the 4th Annual Meeting and Scientific Congress of Taiwan Society for Vascular Surgery, Nantou, Taiwan, 23 - 25 September 2011. 2011.
Cheng S.W.K., Future perspectives for thoracic intervention (Plenary II) (Invited Chairman), Aortic Asia Bali 2012, Bali, Indonesia, 7-8 March 2012. 2012.
Cheng S.W.K., Honorary Consultant in Vascular Surgery (January 2004 - present), Hong Kong Sanatorium & Hospital. 2012.
Cheng S.W.K., Honorary Member (2008 - present), Australasian and New Zealand Society for Vascular Surgery. 2012.
Cheng S.W.K., Honorary Member (2010 - present), Society for Clinical Vascular Surgery. 2012.
Cheng S.W.K., Internal iliac branched grafts - need for preservation?, Aortic Asia Bali 2012, The Laguna, Nusa, Bali, 7-8 March 2012. 2012.
Cheng S.W.K., Invited Chairman for Plenary Lecture III, The 12th Annual Congress of Asian Society for Vascular Surgery and the 6th Asian Venous Forum, Taipei, Taiwan, 29 September - 2 October 2011. 2011.
Cheng S.W.K., Management of chronic aortic dissection - the Hong Kong experience, 2012 Pacific Northwest Endovascular Conference, Seattle, U.S.A., 24 May 2012. 2012.
Cheng S.W.K., Member of Editorial Board (1996 - present), Chinese Journal of Vascular Surgery. 2012.
Cheng S.W.K., Member of Editorial Board (2002 - present), Cutting Edge, College of Surgeons of Hong Kong Newsletter. 2012.
Cheng S.W.K., Novel apporaches to iliac aneurysmal disease: lessons from the East, 2012 Annual Meeting of British Society of Endovascular Therapy (BSET) and Vascular Society, Walton Hall, Walton, Warwickshire, London, United Kingdom, 28 - 29 June 2012. 2012.
Cheng S.W.K., Patient selection and outcomes for fenestrated endografts, Pre-congress Workshop IV sponsored by Cook Medical, The 12th Annual Congress of Asian Society for Vascular Surgery (ASVS) and 6th Asian Venous Forum, Taipei, Taiwan, 29 September - 2 October 2011. 2011.
Cheng S.W.K., Patients selection and outcome with Zenith fenestrated SG Zenith, China Endovascular Course 2011, Beijing, China, 3-6 November 2011. 2011.
Cheng S.W.K., Secretary General (2009 - present), Asian Society for Vascular Surgery. 2012.
Cheng S.W.K., Serena H.C. Yang Professor in Vascular Surgery (April 2005 - present), Endowed Professorship, The University of Hong Kong. 2012.
Cheng S.W.K., Takayasu's diseases with TAAA, without femoral access, and with occluded carotid - a case report, Zenith Endovascular Forum, Aortic Asia Bali 2012, The Laguna, Nusa Dua, Bali, 9 March 2012. 2012.
Cheng S.W.K., The evolution of AAA repair: how far have we come? (Invited Co-moderator), International Endovascular Advance (IEVA) 2011 & the 4th Annual Meeting and Scientific Congress of Taiwan Society for Vascular Surgery, Nantou, Taiwan, 23-25 September 2011. 2011.
Cheng S.W.K., The evolution of endovascular techniques in the Asia-Pacific region: where have we progressed and which challenges are still ahead?, LINC Asia-Pacific Hong Kong 2012, Hong Kong, 1-3 February 2012. 2012.
Cheng S.W.K., Thoracic endografting for chronic aorta dissections and dissecting aneurysms: indications and concerns, China Endovascular Course 2011, Beijing, China, 3-6 November 2011. 2011.
Cheng S.W.K., Thoracic endografting for chronic aortic dissections and dissecting aneurysms: indications and concerns, The 12th Annual Congress of Asian Society for Vascular Surgery (ASVS) and the 6th Asian Venous Forum, Taipei, Taiwan, 29 September - 2 October 2011. 2011.
Cheng S.W.K., Vascular Section Editor (2006 - present), Asian Cardiovascular and Thoracic Annals. 2012.
Cheng S.W.K., 開窗及分叉支架腔內治療的新進展, 第六屆中國南方血管大會 (CSEC 2012) 暨首屆海峽血管論壇, 中國廣州, 14-17 June 2012, 2012.
Cheng S.W.K., 开窗及分叉支架腔内治疗的新进展, 第十四届中国南方国际心血管病学术会议, 中国广州, 11-14 April 2012, 2012.
Cheuk L.Y., Chan Y.C. and Cheng S.W.K., Changes in inflammatory response after endovascular treatment for type B aortic dissection, PLoS One. 2012, 7(5): e37389.
Chua G.T., Chan Y.C. and Cheng S.W.K., Vitamin D status and peripheral arterial disease: evidence so far (Review), Journal of Vascular Health and Risk Management. 2011, 7: 671-675.
Qing K., Yiu W.K. and Cheng S.W.K., A morphologic study of chronic type B aortic dissections and aneurysms after thoracic endovascular stent grafting, Journal of Vascular Surgery. 2012, 55(5): 1268-1276.
Qu Z., Cheuk L.Y. and Cheng S.W.K., Differential expression of sphingosine-1-phosphate receptors in abdominal aortic aneurysms, Mediators of Inflammation. 2012, 2012: 643609.
Szeto G.P.Y., Cheng S.W.K., Poon J.T.C., Ting A.C.W., Tsang R.C.C. and Ho P., Surgeons' static posture and movement repetitions in open and laparoscopic surgery, Journal of Surgical Research. 2012, 172(1): e19-e31.
Yiu W.K. and Cheng S.W.K., Endovascular repair for bleeding aortoenteric fistula is associated with lower perioperative mortality, 2011 Asian Chapter Congress of International Union of Angiology, Beijing, China, 20-22 October 2011.
Yiu W.K., Chan Y.C., Ting A.C.W. and Cheng S.W.K., Para-aortic lymphoma mimicking mycotic abdominal aortic aneurysm: case presentation & review of literature (Poster Presentation), The 12th Annual Congress of the Asian Society for Vascular Surgery (ASVS) and 6th Asian Venous Forum, Taipei, Taiwan, 29 September to 2 October 2011.
Yiu W.K. and Cheng S.W.K., Treating mycotic aortic aneurysms with endovascular stent graft repair (Oral Presentation), The 53rd Annual World Congress of International College of Angiology, Bali, Indonesia, 18 - 20 September 2011.


Researcher : Cheuk LY

Project Title:Analysis of the inflammatory and renal response in endovascular treatment of Stanford Type B Aortic Dissection
Investigator(s):Cheuk LY, Cheng SWK
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2011
Completion Date:06/2012


List of Research Outputs

Cheuk L.Y., Chan Y.C. and Cheng S.W.K., Changes in inflammatory response after endovascular treatment for type B aortic dissection, PLoS One. 2012, 7(5): e37389.
Qu Z., Cheuk L.Y. and Cheng S.W.K., Differential expression of sphingosine-1-phosphate receptors in abdominal aortic aneurysms, Mediators of Inflammation. 2012, 2012: 643609.


Researcher : Cheung CKY

List of Research Outputs

Fung J.Y.Y., Chan S.C., Cheung C.K.Y., Chok K.S.H., Sharr W.W., Chan A.C.Y., Dai W.C., Cheung T.T., Fan S.T., Lai C.L., Yuen R.M.F. and Lo C.M., Entecavir Versus Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B., 18th Annual International Congress on ILTS Location: San Francisco, USA. May 16-19, 2012. Liver Transplantation.. 2012, 18 (supp 1): S124.
Fung J.Y.Y., Cheung C.K.Y., Chan S.C., Yuen R.M.F., Chok K.S.H., Sharr W.W., Dai W.C., Chan A.C.Y., Cheung T.T., Tsang S.H.Y., Lam B.K.Y., Lai C.L. and Lo C.M., Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation, Gastroenterology. 2011, 141(4): 1212-1219.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.


Researcher : Cheung CM

List of Research Outputs

Hui K.C., Chan K.W., Luk J.M.C., Lee N.P.Y., Chung M.F.Y., Cheung C.M., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Cytoplasmic Forkhead Box M1 (FoxM1) in esophageal squamous cell carcinoma significantly correlates with pathological disease stage, World Journal of Surgery. 2012, 36(1): 90-97.


Researcher : Cheung PFY

List of Research Outputs

Cheung P.F.Y., Yip C.W., Wong C.L., Cheng C.K.C., Wong Y.L. and Cheung S.T., Characterization of GEP-expressing cells in human primary hepatocellular carcinoma (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Cheung P.F.Y., Cheng C.K.C., Wong C.L., Ho J.C.Y., Yip C.W., Lui V.C.H., Cheung A.N.Y., Fan S.T. and Cheung S.T., Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells, PLoS One. 2011, 6(12): e28246.
Cheung S.T., Cheung P.F.Y., Cheng C.K.C. and Fan S.T., Genomics approach to identify drug transporter ABCF1 associated with liver cancer recurrence and chemo-resistance (Abstract), The Annual Meeting of the American Association for Cancer Research, Chicago, USA, 31 March - 4 April 2012.
Cheung S.T., Cheung P.F.Y., Cheng C.K.C. and Fan S.T., Genomics approach to identify growth factor and drug transporter associated with liver cancer recurrence and chemo-resistance (Abstract), The 22nd Congress of the Asian Pacific Association for the Study of the Liver, Taipei, Taiwan, 16-19 February 2012.
Lam C.Y., Yip C.W., Poon T.C.W., Cheng C.K.C., Ng E.W.Y., Wong C.L., Cheung P.F.Y., Lai P.B.S., Ng I.O.L., Fan S.T. and Cheung S.T., Identification and characterization of tropomyosin 3 associated with granulin-epithelin precursor in human hepatocellular carcinoma, PLoS One. 2012, 7(7): e40324.
Wong C.L., Cheung P.F.Y. and Cheung S.T., Combined GEP targeted therapy and chemo-therapy eradicated human HCC in orthotopic mouse model (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.


Researcher : Cheung ST

Project Title:Combine targeted therapy with chemotherapy for liver cancer treatment
Investigator(s):Cheung ST, Ho JCY, Fan ST
Department:Surgery
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:10/2007


Project Title:To further characterize GEP as a potential antibody target for HCC
Investigator(s):Cheung ST
Department:Surgery
Source(s) of Funding:Pfizer - General Award
Start Date:10/2009
Completion Date:09/2011


Project Title:To test putative target of HCC recurrence using locked nucleic acids (LNA) as a tool - GEP
Investigator(s):Cheung ST
Department:Surgery
Source(s) of Funding:Pfizer - General Award
Start Date:01/2010


Project Title:Characterize the chemo-resistance cells for stem cell properties in liver cancer
Investigator(s):Cheung ST
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2010
Completion Date:01/2012


Project Title:Characterize the drug transporter ABCB5 in liver cancer
Investigator(s):Cheung ST
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2011


Project Title:Combine GEP antibody targeted therapy and chemotherapy for liver cancer treatment in orthotopic mouse model
Investigator(s):Cheung ST
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2011


Project Title:Study the role of ABCF1 in association with liver cancer recurrence after curative partial hepatectomy
Investigator(s):Cheung ST
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012


Project Title:American Association for Cancer Research Annual Meeting Genomics approach to identify drug transporter ABCF1 associated with liver cancer recurrence and chemo-resistance
Investigator(s):Cheung ST
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:04/2012


List of Research Outputs

Cheung P.F.Y., Yip C.W., Wong C.L., Cheng C.K.C., Wong Y.L. and Cheung S.T., Characterization of GEP-expressing cells in human primary hepatocellular carcinoma (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Cheung P.F.Y., Cheng C.K.C., Wong C.L., Ho J.C.Y., Yip C.W., Lui V.C.H., Cheung A.N.Y., Fan S.T. and Cheung S.T., Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells, PLoS One. 2011, 6(12): e28246.
Cheung S.T., Editorial Board Member, PLoS ONE. 2012.
Cheung S.T., Editorial Board Member, PLoS One. 2011.
Cheung S.T., Editorial Board Member, The Chinese Journal of Medicine. 2012.
Cheung S.T., Editorial Board Member, World Journal of Gastrointestinal Pharmacology and Therapeutics. 2012.
Cheung S.T., Editorial Board Member, World Journal of Hepatology. 2012.
Cheung S.T., Genomic approach to identify growth factor and drug transporter for liver cancer targeted therapy (Oral Presentation), The 70th Annual Meeting of Japanese Cancer Association, Nagoya, Japan, 3-5 October 2011.
Cheung S.T., Genomic approach to identify growth factor and drug transporter for liver cancer targeted therapy, Presentation Award, The Annual Meeting of Japanese Cancer Association, Nagoya, Japan, 3 - 5 October 2011. 2011.
Cheung S.T., Cheung P.F.Y., Cheng C.K.C. and Fan S.T., Genomics approach to identify drug transporter ABCF1 associated with liver cancer recurrence and chemo-resistance (Abstract), The Annual Meeting of the American Association for Cancer Research, Chicago, USA, 31 March - 4 April 2012.
Cheung S.T., Cheung P.F.Y., Cheng C.K.C. and Fan S.T., Genomics approach to identify growth factor and drug transporter associated with liver cancer recurrence and chemo-resistance (Abstract), The 22nd Congress of the Asian Pacific Association for the Study of the Liver, Taipei, Taiwan, 16-19 February 2012.
Cheung S.T., Genomics approach to identify growth factor and drug transporter associated with liver cancer recurrence and chemo-resistance (Oral Presentation), The 22nd Congress of the Asian Pacific Association for the Study of the Liver, Taipei, Taiwan, 16-19 February 2012.
Cheung S.T., Identify novel molecular targets from liver cancer genomic data, The 1st Symposium for the State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, 24 September 2011. 2011.
Cheung S.T., Organizing Committee Member, Symposium 2011, State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, 24 September 2011. 2011.
Cheung S.T., Presentation Award (Genomic approach to identify growth factor and drug transporter for liver cancer targeted therapy), The Annual Meeting of Japanese Cancer Association, Nagoya, Japan, 3-5 October 2011. 2011.
Cheung S.T., Reviewer, Research Grants Council, Hong Kong. 2012.
Cheung S.T., The role of granulin‐epithelin precursor (GEP) on tumor growth and angiogenesis, Croucher Advanced Study Institute, Tumour Microenvironment - New Concepts and Molecular Mechanisms, Hong Kong, 9 - 13 January 2012. 2012.
Lam C.Y., Yip C.W., Poon T.C.W., Cheng C.K.C., Ng E.W.Y., Wong C.L., Cheung P.F.Y., Lai P.B.S., Ng I.O.L., Fan S.T. and Cheung S.T., Identification and characterization of tropomyosin 3 associated with granulin-epithelin precursor in human hepatocellular carcinoma, PLoS One. 2012, 7(7): e40324.
Wong C.L., Cheung P.F.Y. and Cheung S.T., Combined GEP targeted therapy and chemo-therapy eradicated human HCC in orthotopic mouse model (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Wu C., Miao X., Huang L., Che X., Jiang G., Yu D., Yang X., Cao G., Hu Z., Zhou Y., Zuo C., Wang C., Zhang X., Zhou Y., Yu X., Dai W., Wang X. and Cheung S.T., Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations, Nature Genetics. 2011, 44(1): 62-66.
Yip C.W. and Cheung S.T., Characterization of granulin-epithelin precursor (GEP) binding properties on cell surface of hepatoma (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Yip C.W. and Cheung S.T., Characterization of granulin-epithelin precursor (GEP) binding properties on cell surface of hepatoma , The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.


Researcher : Cheung TT

List of Research Outputs

Chan A.C.Y., Poon R.T.P., Cheung T.T., Chok K.S.H., Chan S.C., Fan S.T. and Lo C.M., Survival analysis of re-resection versus radiofrequency ablation for intrahepatic recurrence after hepatectomy for hepatocellular carcinoma, World Journal of Surgery. 2011, Epub on 2011-10-27.
Chan S.C., Lo C.M., Chok K.S.H., Sharr W.W., Cheung T.T., Tsang S.H.Y., Chan A.C.Y. and Fan S.T., Modulation of graft vascular inflow guided by flowmetry and manometry in liver transplantation, Hepatobiliary & Pancreatic Diseases International. 2011, 10(6): 649-656.
Chan S.C., Fan S.T., Chok K.S.H., Cheung T.T., Chan A.C.Y., Fung J.Y.Y., Poon R.T.P. and Lo C.M., Survival advantage of primary liver transplantation for hepatocellular carcinoma within the up-to-7 criteria with microvascular invasion, Hepatology International. 2011, Epub on 2011-10-21.
Cheung T.T., Poon R.T.P., Yau T.C.C., Tsang D.S., Lo C.M. and Fan S.T., High-intensity focused ultrasound as a treatment for colorectal liver metastasis in difficult position (Letter to the Editor), International Journal of Colorectal Disease. 2011, Epub on 2011-08-13.
Cheung T.T., Chan S.C., Chok K.S.H., Chan A.C.Y., Yu W.C., Poon R.T.P., Lo C.M. and Fan S.T., Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma, Hepatobiliary & Pancreatic Diseases International. 2012, 11(3): 267-271.
Cheung T.T., Chu F.S., Jenkins C.R., Tsang D.S., Chok K.S.H., Chan A.C.Y., Yau T.C.C., Chan S.C., Poon R.T.P., Lo C.M. and Fan S.T., Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma, World Journal of Surgery. 2012, Epub on 2012-06-15.
Chiu J., Tang Y.F., Yao T.J., Wong A., Wong H., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Fan S.T., Poon R.T.P. and Yau T.C.C., The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: A retrospective analysis of efficacy, safety, and survival benefits, Cancer. 2012, Epub on 2012-04-19.
Chok K.S.H., Fung J.Y.Y., Chan S.C., Cheung T.T., Sharr W.W., Chan A.C.Y., Fan S.T. and Lo C.M., Outcomes of living donor liver transplantation for patients with preoperative type 1 hepatorenal syndrome and acute hepatic decompensation, Liver Transplantation. 2012, Epub on 2012-01-30.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Fung J.Y.Y., Tsang S.H.Y., Fan S.T. and Lo C.M., Single-centre experience of liver transplantation for familial amyloidotic polyneuropathy of non-Val30Met variants in Chinese patients, Amyloid. 2012, 19(1): 33-36.
Dai W.C., Fan S.T., Cheung T.T., Chok K.S.H., Chan A.C.Y., Tsang S.H.Y., Poon R.T.P. and Lo C.M., The impact of family history of hepatocellular carcinoma on its patients' survival, Hepatobiliary & Pancreatic Diseases International. 2012, 11(2): 160-164.
Fung J.Y.Y., Chan S.C., Cheung C.K.Y., Chok K.S.H., Sharr W.W., Chan A.C.Y., Dai W.C., Cheung T.T., Fan S.T., Lai C.L., Yuen R.M.F. and Lo C.M., Entecavir Versus Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B., 18th Annual International Congress on ILTS Location: San Francisco, USA. May 16-19, 2012. Liver Transplantation.. 2012, 18 (supp 1): S124.
Fung J.Y.Y., Cheung C.K.Y., Chan S.C., Yuen R.M.F., Chok K.S.H., Sharr W.W., Dai W.C., Chan A.C.Y., Cheung T.T., Tsang S.H.Y., Lam B.K.Y., Lai C.L. and Lo C.M., Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation, Gastroenterology. 2011, 141(4): 1212-1219.
Ho C.L., Chen S.R., Cheung T.T., Leung Y.L., Cheng T.K.C. and Wong K.N., Dual-tracer PET/CT for the differential diagnosis of small liver nodules (1-2 cm) in cirrhosis: early HCC or dysplastic nodule? (Abstract), SNM 2012 Annual Meeting, Miami Beach, Florida, USA, 9-13 June 2012. The Journal of Nuclear Medicine. 2012, 53(5, Suppl): not known.
Ho C.L., Chen S.R., Cheung T.T., Cheng T.K.C., Leung Y.L. and Wong K.N., The use of dual-tracer PET/CT in selection of HCC patients based on Milan criteria before liver transplant (Abstract), SNM 2012 Annual Meeting, Miami Beach, Florida, USA, 9-13 June 2012. The Journal of Nuclear Medicine. 2012, 53(5, Suppl): not known.
Ho C.L., Cheung M.K., Chen S., Cheung T.T., Leung Y.L., Cheng K.C. and Yeung W.D., [18F]fluoroacetate positron emission tomography for hepatocellular carcinoma and metastases: an alternative tracer for [11C]acetate?, Molecular Imaging. 2011, 11(3): 229-239.
Wong H., Tang Y.F., Yao T., Chiu J., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Poon R.T.P., Fan S.T. and Yau T.C.C., The outcomes and safety of single-agent sorafenib in the treatment of elderly patients with advanced hepatocellular carcinoma (HCC), Oncologist. 2011, 16(12): 1721-1728.
Yau T.C.C., Wong H., Chan P., Yao T., Pang R.W.C., Cheung T.T., Fan S.T. and Poon R.T.P., Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease, Investigational New Drugs. 2012, Epub on 2012-03-09.


Researcher : Chok KSH

List of Research Outputs

Chan A.C.Y., Poon R.T.P., Cheung T.T., Chok K.S.H., Chan S.C., Fan S.T. and Lo C.M., Survival analysis of re-resection versus radiofrequency ablation for intrahepatic recurrence after hepatectomy for hepatocellular carcinoma, World Journal of Surgery. 2011, Epub on 2011-10-27.
Chan S.C., Lo C.M., Chok K.S.H., Sharr W.W., Cheung T.T., Tsang S.H.Y., Chan A.C.Y. and Fan S.T., Modulation of graft vascular inflow guided by flowmetry and manometry in liver transplantation, Hepatobiliary & Pancreatic Diseases International. 2011, 10(6): 649-656.
Chan S.C., Fan S.T., Chok K.S.H., Cheung T.T., Chan A.C.Y., Fung J.Y.Y., Poon R.T.P. and Lo C.M., Survival advantage of primary liver transplantation for hepatocellular carcinoma within the up-to-7 criteria with microvascular invasion, Hepatology International. 2011, Epub on 2011-10-21.
Cheung T.T., Chan S.C., Chok K.S.H., Chan A.C.Y., Yu W.C., Poon R.T.P., Lo C.M. and Fan S.T., Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma, Hepatobiliary & Pancreatic Diseases International. 2012, 11(3): 267-271.
Cheung T.T., Chu F.S., Jenkins C.R., Tsang D.S., Chok K.S.H., Chan A.C.Y., Yau T.C.C., Chan S.C., Poon R.T.P., Lo C.M. and Fan S.T., Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma, World Journal of Surgery. 2012, Epub on 2012-06-15.
Chok K.S.H., Interim treatments in patients for liver transplantation for hepatocellular carcinoma (Presentation), Hong Kong society of Transplantation. Annual Scientific Meeting and Annual General Meeting, Hong Kong, 22 April 2012.
Chok K.S.H., Fung J.Y.Y., Chan S.C., Cheung T.T., Sharr W.W., Chan A.C.Y., Fan S.T. and Lo C.M., Outcomes of living donor liver transplantation for patients with preoperative type 1 hepatorenal syndrome and acute hepatic decompensation, Liver Transplantation. 2012, Epub on 2012-01-30.
Chok K.S.H., Chan S.C., Poon R.T.P., Fan S.T. and Lo C.M., Re-resection for metachronous primary hepatocellular carcinoma: is it justified?, ANZ Journal of Surgery. 2012, 82(1-2): 63-67.
Chok K.S.H., Risk factors associated with failed endoscopic treatment for biliary anastomotic stricture after right lobe living donor liver transplantation (Oral Presentation), The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Fung J.Y.Y., Tsang S.H.Y., Fan S.T. and Lo C.M., Single-centre experience of liver transplantation for familial amyloidotic polyneuropathy of non-Val30Met variants in Chinese patients, Amyloid. 2012, 19(1): 33-36.
Dai W.C., Fan S.T., Cheung T.T., Chok K.S.H., Chan A.C.Y., Tsang S.H.Y., Poon R.T.P. and Lo C.M., The impact of family history of hepatocellular carcinoma on its patients' survival, Hepatobiliary & Pancreatic Diseases International. 2012, 11(2): 160-164.
Fung J.Y.Y., Chan S.C., Cheung C.K.Y., Chok K.S.H., Sharr W.W., Chan A.C.Y., Dai W.C., Cheung T.T., Fan S.T., Lai C.L., Yuen R.M.F. and Lo C.M., Entecavir Versus Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B., 18th Annual International Congress on ILTS Location: San Francisco, USA. May 16-19, 2012. Liver Transplantation.. 2012, 18 (supp 1): S124.
Fung J.Y.Y., Cheung C.K.Y., Chan S.C., Yuen R.M.F., Chok K.S.H., Sharr W.W., Dai W.C., Chan A.C.Y., Cheung T.T., Tsang S.H.Y., Lam B.K.Y., Lai C.L. and Lo C.M., Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation, Gastroenterology. 2011, 141(4): 1212-1219.
Fung J.Y.Y., Chan S.C., Yuen R.M.F., Lai C.L., Chok K.S.H., Sharr W.W., Dai W.C., Fan S.T. and Lo C.M., Long-term Outcome of Lamivudine Mono-prophylaxis After Liver Transplantation In Hepatitis B Patients , 62nd Annual Meeting Of The American-association-for-the-study-of-liver-diseases (AASLD) Location: San Francisco, USA. November 04-08, 2011. Hepatology . 2011, 54(Supp 1): 450A-450A.
Siriwardana R.C., Chan S.C., Chok K.S.H., Lo C.M. and Fan S.T., Effects of the liver volume and donor steatosis on errors in the estimated standard liver volume, Liver Transplantation. 2011, 17(12): 1437-1442.


Researcher : Chow HM

List of Research Outputs

Chow H.M., Tam P.K.H. and Ngan E.S.W., Neural crest and Hirschsprung’s disease, In: Srivastava R.K. and Shankar S. (eds.), Stem Cell and Human Diseases. New York, Springer, 2011, 353-386.
Chow H.M., Yung S.Y.J. and Ngan E.S.W., Neural crest derived from Hirschsprung iPS cells show a reduced neural plasticity, Days of Molecular Medicine 2011, Hong Kong, 10-12 November 2011.
Yung S.Y.J., Chow H.M., Tse H.F., Tam P.K.H. and Ngan E.S.W., Generation of patient-specific iPSCs for Hirschsprung's disease modelling, Days of Molecular Medicine 2011, Hong Kong, 10-12 November 2011.


Researcher : Chow KM

Project Title:The potential therapeutic efficacy of Raf265 in targeting the cancer stem cell subpopulation in colorectal cancer
Investigator(s):Chow KM, Pang RWC, Poon RTP
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2012




Researcher : Chow LWC

Project Title:Chemosensitivity study using a breast cancer cell line
Investigator(s):Chow LWC
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:05/1996




Researcher : Chu ATW

List of Research Outputs

Ho S.M.Y., Ho J.W.C., Pau B.K.Y., Hui B.P.H., Wong R.S.M. and Chu A.T.W., Hope-based intervention for individuals susceptible to colorectal cancer: a pilot study, Familial Cancer. 2012, Epub ahead of print.
Kwong A. and Chu A.T.W., A retrospective study on surveillance behaviours and prophylasix after genetic testing for hereditary breast and ovarian cancer among high-risk Chinese females, The San Antonio Breast Cancer Symposium, San Antonio, California, U.S.A., 6 - 10 December 2011.
Ma K...K..., Chu A.T.W. and Kwong A., A qualitative study on psychosocial impact of contralateral prophylactic mastectomy among breast cancer female patients who underwent Brca1 and Brca2 genetic testing in Hong Kong China, International Surgical Week (ISW), Yokohama, Japan, 28 August - 1 September 2011.


Researcher : Chu KM

Project Title:Circulating microRNAs in plasma as biomarkers for early non-invasive diagnosis of gastric cancer
Investigator(s):Chu KM, Shin VY
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


List of Research Outputs

Chan W.M., Lau L.S., Kwok K.M., Law W.L., Ho J.C.M., Chu K.M. and Poon R.T.P., A randomized, double-blind, placebo-controlled, ascending dose infusion trial of the pharmacokinetics of recombinant human Gelsolin in patients with decreased natural Gelsolin levels, American Thoracic Society International Conference, Denver, U.S.A., 13 - 18 May 2011. American Journal of Respiratory and Critical Care Medicine. 2011, 183: A5601.
Chu K.M., Associate Editor (2005 - present), Asian Journal of Surgery. 2012.
Chu K.M., Associate Member (1996 - present), Hereditary Gastrointestinal Cancer Registry, Hong Kong. 2012.
Chu K.M., Be careful of getting stuck in throat, Weekly Health Column in Oriental Daily News by Li Ka Shing Faculty of Medicine. 2012.
Chu K.M., Benign and malignant diseases of the stomach and cardia, Preparatory Course for Macau SAR Medical Graduates, Macau SAR Health Bureau and Macau University of Science and Technology's Faculty of Health Science, Macau, 8 January 2012. 2012.
Chu K.M., Chairman for the Session "How I Do It?", The 1st Enteroscopy Workshop, The University of Hong Kong, Hong Kong, 23 - 24 September 2011. 2011.
Chu K.M., Chairman, The 41st Clinical Meeting of Hong Kong Society of Minimal Access Surgery, Queen Mary Hospital, Hong Kong, 12 April 2012. 2012.
Chu K.M., Common types of upper GI diseases and cancers, Post-registration Certificate Course in Advanced Surgical Nursing, Hong Kong, 24 February 2012. 2012.
Chu K.M., Council Member (August 2006 - present), The Federation of Medical Societies of Hong Kong. 2012.
Chu K.M., Council Member (February 2004 - present), Gerson Lehrman Group's Council of Healthcare Advisors, Gerson Lehrman Group, New York, USA. 2012.
Chu K.M., Council Member (June 2006 - present), Hong Kong Society of Upper Gastrointestinal Surgeons. 2012.
Chu K.M., Council Member (September 2010 - present), Hong Kong Society of Minimal Access Surgery. 2012.
Chu K.M., Council Member (September 2011 - present), The College of Surgeons of Hong Kong. 2012.
Chu K.M., Current evidence on the application of laparoscopic gastrectomy for cancer, The AETF 15th Workshop on Laparoscopic Upper GI Surgery, The Research Institute against Cancer of the Digestive Tract Taiwan Training Center, Changhwa, Taiwan, 7 - 8 September 2011. 2011.
Chu K.M., Current status of laparoscopic surgery for gastric cancer in Hong Kong, Dong-A Laparoscopic Gastrectomy Symposium, Busan, Korea, 24 March 2012. 2012.
Chu K.M., Deputy Chairman (December 2007 - present), Institutional Review Board of The University of Hong Kong / Hospital Authority Hong Kong West Cluster. 2012.
Chu K.M., Director, Advances in Endoscopy 2012, Departments of Surgery and Medicine, Queen Mary Hospital and Tung Wah Hospital, Hong Kong, 24 March 2012. 2012.
Chu K.M., Director, Critical Appraisal Skills Workshop for Surgery, Hospital Authority Central Commissioned Training Programme, The University of Hong Kong, Hong Kong, 5 - 6 January 2012. 2012.
Chu K.M., Director, Hong Kong Surgical Forum - Summer, The University of Hong Kong, Hong Kong, 16 July 2011. 2011.
Chu K.M., Director, The 3rd Master Workship on Gastric Surgery, The University of Hong Kong, Hong Kong, 15 July 2011. 2011.
Chu K.M., Director, The 4th Master Workshop on Gastric Surgery and Endoscopy, Departments of Surgery, Medicine and Anatomy, Queen Mary Hospital, The University of Hong Kong, Hong Kong, 4 - 5 May 2012. 2012.
Chu K.M., ESD for a gastric nodule embedded in muscularis, Hong Kong Surgical Forum - Summer, The University of Hong Kong, Hong Kong, 16 July 2011. 2011.
Chu K.M., Endoscopic and surgical intervention for morbid obesity and metabolic syndrome, Update on Diabetes Management (A Certificate Course for Clinicians), The University of Hong Kong, Hong Kong, 26 - 27 November 2011. 2011.
Chu K.M., Examination Committee Member (July 2007 - present), The College of Surgeons of Hong Kong. 2012.
Chu K.M., Expert Reviewer (July 2000 - present), Fellowships Programme, Union for International Cancer Control, Geneva, Switzerland. 2012.
Chu K.M., Expert Reviewer for Yamagiwa-Yoshida Memorial International Cancer Study Grant, International Union Against Cancer (Fellowships Application). 2012.
Chu K.M., External Advisor / Reviewer (September 1999 - present), Quality Education Fund Projects, Quality Education Fund, Hong Kong. 2012.
Chu K.M., Honorary Consultant in Gastrointestinal Surgery (March 1999 - present), Tung Wah Hospital, Hong Kong. 2012.
Chu K.M., Honorary Consultant in Surgery (January 2005 - present), Hong Kong Sanatorium & Hospital. 2012.
Chu K.M., Improve outcome and survival in the management of GIST, Macau Gastrointestinal Stromal Tumor Clinical Update Meeting, Macau, 22 June 2012. 2012.
Chu K.M., Invited International Review Panel, Union for International Cancer Control 2012 World Cancer Congress, Montreal, Canada, 27 - 30 August 2012. 2012.
Chu K.M., Invited Referee (Reviewer) (July 2011 - present), World Journal of Surgery. 2011.
Chu K.M., Invited Referee (Reviewer), Case Reports in Medicine (January, February, May). 2012.
Chu K.M., Invited Referee (Reviewer), Gastroenterology (January, May). 2012.
Chu K.M., Laboratory Instructor, The AETF 15th Workshop on Laparoscopic Upper GI Surgery, The Research Institute against Cancer of the Digestive Tract Taiwan Training Center, Changhwa, Taiwan, 7 - 8 September 2011. 2011.
Chu K.M., Member (July 2001 - present), Expert Panel in Surgery for Hospital Authority's Complaint and Potential Medicolegal Cases, Hospital Authority, Hong Kong. 2012.
Chu K.M., Member (May 2010 - present), Hong Kong West Cluster Credentialing Committee, Queen Mary Hospital, Hong Kong. 2012.
Chu K.M., Member (October 2004 - present), Examination Sub-committee, Licentiate Committee, The Medical Council of Hong Kong. 2012.
Chu K.M., Member (September 2006 - present), Task Force for Subspecialization in General Surgery, The College of Surgeons of Hong Kong. 2012.
Chu K.M., Member (September 2010 - present), Ambulatory Centre Management Committee, Queen Mary Hospital, Hong Kong. 2012.
Chu K.M., Member of Board of Advisors (July 2009 - present), Health Action Magazine, Hong Kong. 2012.
Chu K.M., Member of Editorial Board (2000 - present), Annals of Cancer Research and Therapy. 2012.
Chu K.M., Member of Editorial Board (2003 - present), Cancer Therapy. 2012.
Chu K.M., Member of Editorial Board (2005 - present), Journal of Chinese Clinical Medicine (formerly Chinese Journal of Medicine) . 2012.
Chu K.M., Member of Editorial Board (2006 - present), World Journal of Surgery. 2012.
Chu K.M., Member of Editorial Board (2008 - present), Case Reports in Medicine. 2012.
Chu K.M., Member of Editorial Board (2010 - present), International Journal of Clinical Medicine. 2012.
Chu K.M., Member of Editorial Board, International Advisory Board for Malaysian Journal of Medicine and Health Sciences (since 2010) . 2012.
Chu K.M., Member of Editorial Board, International Advisory Board for Schzartz's Principles of Surgery 9th Edition (since 2008). 2012.
Chu K.M., Member of International Advisory Board (2008 - present), Schwartz's Principles of Surgery 9th Edition. 2012.
Chu K.M., Member of International Advisory Board (2010 - present), Malaysian Journal of Medicine and Health Sciences. 2012.
Chu K.M., Member or Board of Examiners (July 2008 - present), Membership Examination, The College of Surgeons of Hong Kong. 2012.
Chu K.M., Member, Cluster Combined Endoscopy Service Task Group, Hong Kong West Cluster, Hospital Authority, Hong Kong. 2012.
Chu K.M., Member, Cluster Committee for Surgical Interventional & Procedural Safety, Hospital Authority Hong Kong West Cluster, Queen Mary Hospital, Hong Kong (August 2011 - now). 2012.
Chu K.M., Member, Cluster Committee for Surgical Interventional & Procedural Safety, Queen Mary Hospital, Hong Kong West Cluster, Hospital Authority, Hong Kong. 2012.
Chu K.M., Minimally invasive surgery for the stomach, Joint Surgical Symposium, Block I of 3-Year Interactive Program, The University of Hong Kong and Hong Kong Sanatorium & Hospital, Hong Kong, 6 January 2012. 2012.
Chu K.M., Peptic ulcer disease and Helicobacter pylori, In: Bland K.I., Buchler M.W., Csendes A., Garden O.J., Sarr M.G. and Wong J. (eds.), Surgery of the Esophagus and Stomach. London, Springer, 2011, 137-154.
Chu K.M., Reconstruction after gastrectomy - Session on "Upper G.I. Surgery", Annual Scientific Meeting 2011, The College of Surgeons of Hong Kong and Macau Surgical Association, Hong Kong, 17 - 18 September 2011. 2011.
Chu K.M., Research Committee Member (October 2002 - present), The College of Surgeons of Hong Kong. 2012.
Chu K.M., Sentinel Reader (January 2007 - present), McMaster Online Rating of Evidence (MORE), McMaster University, Hamilton, Ontario, Canada. 2012.
Chu K.M., Start writing - case report and retrospective cohort study, Research Training Workshop for Higher Surgical Trainees, The College of Surgeons of Hong Kong, Hong Kong, 24 February 2012. 2012.
Chu K.M., You are what you eat - diet and upper gastrointestinal and related conditions, HKU100 Centenary Celebrations, Public Lecture Series, The University of Hong Kong, Hong Kong, 10 September 2011. 2011.
Fan B., Dachrut S., Coral H., Yuen S.T., Chu K.M., Law S.Y.K., Zhang L., Ji J., Leung S.Y. and Chen X., Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer, PLoS One. 2012, 7(4): e29824.
Ng E.K.O., Leung P.H.C., Shin V.Y., Wong L.P., Ma E.S.K., Jin H.C., Chu K.M. and Kwong A., Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients, PLoS One. 2011, 6(7): e22233.
Wang K., Kan J., Yuen S.T., Shi S.T., Chu K.M., Law S.Y.K., Chan T.L., Kan Z., Chan A.S.Y., Tsui W.Y., Lee S.P., Ho R.S.L., Chan K.W., Cheng H.W.G., Roberts P.C., Rejto P.A., Gibson N.W., Pocalyko D.J., Mao M., Xu J. and Leung S.Y., Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer, AACR Special Conference on Translation of the Cancer Genome: Scientific, Clinical, and Operational Challenges, San Francisco, CA, U.S.A. October. 2011.
Wang K., Kan J., Yuen S.T., Shi S.T., Chu K.M., Law S.Y.K., Chan T.L., Kan Z., Chan A.S.Y., Tsui W.Y., Lee S.P., Ho R.S.L., Chan K.W., Cheng H.W.G., Roberts P.C., Rejto P.A., Gibson N.W., Pocalyko D.J., Mao M., Xu J. and Leung S.Y., Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer, Nature Genetics. 2011, 43(12): 1219-1223.
Wang K., Kan J., Yuen S.T., Shi S.T., Chu K.M., Law S.Y.K., Chan T.L., Kan Z., Chan A.S.Y., Tsui W.Y., Lee S.P., Ho R.S.L., Chan K.W., Cheng H.W.G., Roberts P.C., Rejto P.A., Gibson N.W., Pocalyko D.J., Mao M., Xu J. and Leung S.Y., Faculty Outstanding Research Output Award "Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer", Nat Genet. 2011, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2012, 43(12): 1219-23.
Wong C.S., Gong N., Chu Y.C., Anthony M., Chan Q., Lee H.F., Chu K.M. and Khong P.L., Correlation of measurements from diffusion weighted MR imaging and FDG PET/CT in GIST patients: ADC versus SUV, European Journal of Radiology. 2012, 81(9): 2122-2126.


Researcher : Chung HP

List of Research Outputs

Chan Y.W., Li G.K.H., Chung H.P. and Chow V.L.Y., Extramammary Paget's disease: 20 years of experience in Chinese population, International Journal of Surgical Oncology. 2012, Epub ahead of print.
Chow V.L.Y., Chan Y.W., Chan R.C., Chung H.P. and Wei W.I., Basal cell carcinoma of the head and neck region in ethnic Chinese, International Journal of Surgical Oncology. 2011, Epub on 14 September 2011.


Researcher : Chung HY

List of Research Outputs

Chan K.L., Chung H.Y., Chan S.C. and Tam P.K.H., Timely liver transplantation is essential for the survival of paediatric patients with hepatopulmonary syndrome, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Chung H.Y., Chan K.L., Chan I.H.Y., Ng I.O.L., Chan G.C.F., Chan S.C. and Tam P.K.H., Clinical experience in managing post transplant lymphoproliferative disease (PTLD) in paediatric patients after liver transplant, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Huang J.S., Chung H.Y., Chan I.H.Y., Tao Q., Wong K.K.Y. and Tam P.K.H., Early outcomes of thoracoscopic repair of congenital diaphragmatic hernia (CDH): two centres' experience, IPEG's 21st Annual Congress for Endosurgery in Children, San Diego, U.S.A., 6 - 10 March 2012.
Huang J.S., Tao J.F., Chen K., Dai K.L., Tao Q., Chan I.H.Y., Chung H.Y., Lan L.C.L., Tam P.K.H. and Wong K.K.Y., Thoracoscopic repair of oesophageal atresia: experience of 33 patients from two tertiary referral centres, The 45th Annual Meeting of the Pacific Association of Pediatric Surgeons, Shanghai, China, 3 - 7 June 2012.
Leung J.L., Chung H.Y., Lan L.C.L., Wong K.K.Y. and Tam P.K.H., Management of tracheobronchial obstruction in infants using metallic stents: long-term outcome, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3 - 7 June 2012.
Leung J.L., Chung H.Y., Chan I.H.Y., Wong R.M.S., Chan A.W.S., Tam P.K.H. and Wong K.K.Y., The use of omega-3-fatty acid for short bowel syndrome patients accelerates reversal of cholestasis, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.


Researcher : Chung MFY

List of Research Outputs

Hui K.C., Chan K.W., Luk J.M.C., Lee N.P.Y., Chung M.F.Y., Cheung C.M., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Cytoplasmic Forkhead Box M1 (FoxM1) in esophageal squamous cell carcinoma significantly correlates with pathological disease stage, World Journal of Surgery. 2012, 36(1): 90-97.


Researcher : Cornes BK

List of Research Outputs

So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.


Researcher : Cui L

List of Research Outputs

Cui L., Wong E.H.M., Zhu J., Almeida M.F. .D.E., Tam P.K.H. and Garcia-Barcelo M.M., Genetic study of a family segregating Shah-Waardenburg syndrome, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tam P.K.H., Garcia-Barcelo M.M., Tang S.M., Yeung M.Y., Cheng G., Wong E.H.M., Cui L., Cherny S.S. and Sham P.C., Genetic studies of congenital gastrointestinal diseases (Invited Lecture), The 13th SCBA (Society of Chinese Bioscientists in America) International Symposium, Sun Yat-sen University, Guangzhou, China, 25 - 19 July 2011. 2011.


Researcher : Fan JKM

List of Research Outputs

Law W.L., Poon T.C.J., Fan J.K.M. and Lo O.S.H., Survival following laparoscopic versus open resection for colorectal cancer, International Journal of Colorectal Disease. 2012, Epub ahead of print.
Poon J.T.C., Law W.L., Chow L.C., Fan J.K.M. and Lo O.S.H., Outcome of laparoscopic resection for colorectal cancer in patients with high operative risk, Annals of Surgical Oncology. 2011, 18(7): 1884-1890.
Poon T.C.J., Cheung C.W., Law W.L., Fan J.K.M. and Lo O.S.H., A randomized controlled trial comparing the outcomes of patients who undergo single port laparoscopic colectomy and conventional laparoscopic colectomy, SAGES 2012, San Diego, California. 7-10 March . 2012.
Poon T.C.J., Cheung C.W., Fan J.K.M., Lo O.S.H. and Law W.L., Single incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized controlled trial, The Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting 2012, San Diego, California, U.S.A., 7 - 10 March 2012.
Poon T.C.J., Cheung C.W., Fan J.K.M., Lo O.S.H. and Law W.L., Single-incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized, controlled trial, Surgical endoscopy. 2012, Epub ahead of print.
She W.H., Poon T.C.J., Fan J.K.M., Lo O.S.H. and Law W.L., Stoma reversal in patients who underwent low anterior resection and diversion stoma for rectal cancer, Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Wong K.P., Poon T.C.J., Fan J.K.M. and Law W.L., Prognostic value of lymph node ratio in stage III colorectal disease, Colorectal Disease. 2011, 13(10): 1116-1122.


Researcher : Fan ST

Project Title:S.K. Yee Medical Foundation Fellowship in hepatobiliary surgery
Investigator(s):Fan ST
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:11/2000


List of Research Outputs

Chan A.C.Y. and Fan S.T., Caudate lobe resection, In: Chattopadhyay T.K., Sahni P. and Pal S. (eds.), GI Surgery. Annual Volume 18. Supplement on operatives procedures: Liver. Madras, Indian Association of Surgical Gastroenterology, 2011, 18: not known.
Chan A.C.Y., Poon R.T.P., Cheung T.T., Chok K.S.H., Chan S.C., Fan S.T. and Lo C.M., Survival analysis of re-resection versus radiofrequency ablation for intrahepatic recurrence after hepatectomy for hepatocellular carcinoma, World Journal of Surgery. 2011, Epub on 2011-10-27.
Chan S.C. and Fan S.T., Hepatic resection for living donor transplantation, In: Jarnagin W.R. (ed.), Blumgart's Surgery of the Liver, Biliary Tract, and Pancreas, 5th edition. Philadelphia, Elsevier Saunders, 2012, 2: 1520-1528.
Chan S.C., Lo C.M., Chok K.S.H., Sharr W.W., Cheung T.T., Tsang S.H.Y., Chan A.C.Y. and Fan S.T., Modulation of graft vascular inflow guided by flowmetry and manometry in liver transplantation, Hepatobiliary & Pancreatic Diseases International. 2011, 10(6): 649-656.
Chan S.C., Fan S.T. and Wong J., Recurrent pyogenic cholangitis, In: Jarnagin W.R. (ed.), Blumgart’s Surgery of the Liver, Biliary Tract, and Pancreas, 5th edition. Philadelphia, Elsevier Saunders, 2012, 1: 680-696.
Chan S.C., Fan S.T., Chok K.S.H., Cheung T.T., Chan A.C.Y., Fung J.Y.Y., Poon R.T.P. and Lo C.M., Survival advantage of primary liver transplantation for hepatocellular carcinoma within the up-to-7 criteria with microvascular invasion, Hepatology International. 2011, Epub on 2011-10-21.
Cheung P.F.Y., Cheng C.K.C., Wong C.L., Ho J.C.Y., Yip C.W., Lui V.C.H., Cheung A.N.Y., Fan S.T. and Cheung S.T., Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells, PLoS One. 2011, 6(12): e28246.
Cheung S.T., Cheung P.F.Y., Cheng C.K.C. and Fan S.T., Genomics approach to identify drug transporter ABCF1 associated with liver cancer recurrence and chemo-resistance (Abstract), The Annual Meeting of the American Association for Cancer Research, Chicago, USA, 31 March - 4 April 2012.
Cheung S.T., Cheung P.F.Y., Cheng C.K.C. and Fan S.T., Genomics approach to identify growth factor and drug transporter associated with liver cancer recurrence and chemo-resistance (Abstract), The 22nd Congress of the Asian Pacific Association for the Study of the Liver, Taipei, Taiwan, 16-19 February 2012.
Cheung T.T., Poon R.T.P., Yau T.C.C., Tsang D.S., Lo C.M. and Fan S.T., High-intensity focused ultrasound as a treatment for colorectal liver metastasis in difficult position (Letter to the Editor), International Journal of Colorectal Disease. 2011, Epub on 2011-08-13.
Cheung T.T., Chan S.C., Chok K.S.H., Chan A.C.Y., Yu W.C., Poon R.T.P., Lo C.M. and Fan S.T., Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma, Hepatobiliary & Pancreatic Diseases International. 2012, 11(3): 267-271.
Cheung T.T., Chu F.S., Jenkins C.R., Tsang D.S., Chok K.S.H., Chan A.C.Y., Yau T.C.C., Chan S.C., Poon R.T.P., Lo C.M. and Fan S.T., Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma, World Journal of Surgery. 2012, Epub on 2012-06-15.
Chiu J., Tang Y.F., Yao T.J., Wong A., Wong H., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Fan S.T., Poon R.T.P. and Yau T.C.C., The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: A retrospective analysis of efficacy, safety, and survival benefits, Cancer. 2012, Epub on 2012-04-19.
Chok K.S.H., Fung J.Y.Y., Chan S.C., Cheung T.T., Sharr W.W., Chan A.C.Y., Fan S.T. and Lo C.M., Outcomes of living donor liver transplantation for patients with preoperative type 1 hepatorenal syndrome and acute hepatic decompensation, Liver Transplantation. 2012, Epub on 2012-01-30.
Chok K.S.H., Chan S.C., Poon R.T.P., Fan S.T. and Lo C.M., Re-resection for metachronous primary hepatocellular carcinoma: is it justified?, ANZ Journal of Surgery. 2012, 82(1-2): 63-67.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Fung J.Y.Y., Tsang S.H.Y., Fan S.T. and Lo C.M., Single-centre experience of liver transplantation for familial amyloidotic polyneuropathy of non-Val30Met variants in Chinese patients, Amyloid. 2012, 19(1): 33-36.
Dai W.C., Fan S.T., Cheung T.T., Chok K.S.H., Chan A.C.Y., Tsang S.H.Y., Poon R.T.P. and Lo C.M., The impact of family history of hepatocellular carcinoma on its patients' survival, Hepatobiliary & Pancreatic Diseases International. 2012, 11(2): 160-164.
Fan S.T., Advisor, Liver Donation Committee, The Hong Kong Liver Foundation. 2012.
Fan S.T., Advisor, The Hong Kong Transplant Sports Association. 2012.
Fan S.T., Appointed Director, The Hong Kong Liver Transplant Patients’ Association. 2012.
Fan S.T., Associate Editor, 中華移植雜誌 (電子版), 2011.
Fan S.T., Associate Editor, Hepatology International. 2011.
Fan S.T., Caudate lobe resection (Invited Lecture), Update Course in Liver Resection by Hong Kong Society of Hepatobiliary and Pancreatic Surgery, Hong Kong, 16 June 2012. 2012.
Fan S.T., Chairman - Symposium 5: Endoscopy in diagnosis and therapy, Li Shu Pui Symposium 2012 – Contemporary Medical Practice, Hong Kong Sanatorium & Hospital, Hong Kong, 17 June 2012. 2012.
Fan S.T., Chairman - What’s new in liver transplantation (1), 21st World Congress of the International Association of Surgeons, Gastroenterologists and Oncologists, Tokyo, Japan, 9-12 November 2011. 2011.
Fan S.T., Yau T.C.C. and Poon R.T.P., Comprehensive management of hepatocellular carcinoma, Chinese Journal of Digestive Surgery. 2011, 10(4): 241-246.
Fan S.T., Current management of hepatocellular carcinoma (Abstract and Invited Lecture), Hepatocellular Carcinoma Symposium 2011, Singapore, 25 July 2011. 2011.
Fan S.T., Current status of hepatocellular carcinoma treatment (Abstract and State-of-the-art Lecture), Asian Pacific Digestive Week 2011, Singapore, 1-4 October 2011. 2011.
Fan S.T., Current status of treatment of hepatocellular carcinoma (Invited Lecture), Inauguration and First Annual Scientific Meeting – Hong Kong Society of Hepatobiliary and Pancreatic Surgery, Hong Kong, 13 January 2012. 2012.
Fan S.T., Current treatment results of HCC (Abstract and Invited Lecture), The 4th Joint Scientific Meeting of The Royal College of Radiologists and Hong Kong College of Radiologists and the 19th Annual Scientific Meeting of Hong Kong College of Radiologists, Hong Kong, 29 - 30 October 2011. 2011.
Fan S.T., Current treatment results of liver cancer by hepatectomy (Invited Lecture), Hong Kong Sanatorium & Hospital – University of California, San Francisco Scientific Symposium, Hong Kong, 2 December 2011. 2011.
Fan S.T., Director, China Liver Transplant Registry. 2012.
Fan S.T., Downstaging of HCC: current evidence (Invited Lecture), The Internationl Liver Symposium, Delhi, India, 24-27 August 2011. 2011.
Fan S.T., Evolving strategies on the treatment of HCC: surgeon’s perspective (Abstract and Invited Lecture), The 22nd Conference of the Asian Pacific Association for the Study of the Liver, Taipei, Taiwan, 16 - 19 February 2012. 2012.
Fan S.T., Expanding horizon of liver surgery (Oration), Institute of Liver and Biliary Sciences Liver Transplantation Oration, Delhi, India, 15 March 2012. 2012.
Fan S.T., Innovation and liver surgery (Oration), The 4th Gyan Burman Oration, Delhi, India, 25 August 2011. 2011.
Fan S.T., Live donor liver transplantation – the Hong Kong perspective (Abstract and Invited Lecture), Stockholm Liver Week 2012, Stockholm, Sweden, 9-11 February 2012. 2012.
Fan S.T., Liver transplantation - overview (Abstract and Invited Postgraduate Lecture), The 3rd Biennial Congress of the Asian Pacific Hepato Pancreato Biliary Association, Melbourne, Australia, 27 - 30 September 2011. 2011.
Fan S.T., Liver transplantation for HCC (Abstract and Plenary Lecture), The 14th International Symposium on Viral Hepatitis and Liver Disease, Shanghai, China, 22 - 25 June 2012. 2012.
Fan S.T., Liver transplantation in Asia: problems and solutions (Invited Lecture), The 67th Annual Clinical Congress - Philippine College of Surgeons, Manila, Philippines, 4 - 7 December 2011. 2011.
Fan S.T., Liver transplantation in Hong Kong (Invited Lecture), Two Decades of Liver Transplantation in Hong Kong, Hong Kong, 8 October 2011. 2011.
Fan S.T., Living donor liver transplantation for HCC (Abstract and Invited Lecture), The 3rd Biennial Congress of the Asian Pacific Hepato Pancreato Biliary Association, Melbourne, Australia, 27 - 30 September 2011. 2011.
Fan S.T., Major hepatic resection for primary and metastatic tumors, In: Fischer J.E. (ed.), Fischer's Mastery of Surgery, 6th edition. Philadelphia, Lippincott Williams & Wilkins, 2012, 1: 1217-1232.
Fan S.T., Management of hepatocellular carcinoma (Plenary Lecture), The 67th Annual Clinical Congress - Philippine College of Surgeons, Manila, Philippines, 4 - 7 December 2011. 2011.
Fan S.T., Moderator - Asbract Session: Living donor, The 18th Annual International Congress, the International Liver Transplantation Society, San Francisco, USA, 16-19 May 2012. 2012.
Fan S.T., Moderator - Best treatment for small HCC in compensated cirrhotics: resection vs. transplant, The Internationl Liver Symposium, Delhi, India, 24-27 August 2011. 2011.
Fan S.T., Moderator - Parallel Session 25: Liver Transplantation, 14th International Symposium on Viral Hepatitis and Liver Disease, Shanghai, China, 22-25 June 2012. 2012.
Fan S.T., Moderator - Session IV, The First Symposium on Cancer Staging and Prognostication in China, Hong Kong, China, 10 September 2011. 2011.
Fan S.T., Multimodality treatment of liver cancer (Abstract and State-of-the-art Lecture), The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011. 2011.
Fan S.T., Optimizing biliary reconstruction in liver transplantation (Invited Lecture), The 67th Annual Clinical Congress - Philippine College of Surgeons, Manila, Philippines, 4 - 7 December 2011. 2011.
Fan S.T., Parenchyma sparing liver surgery (Abstract and State-of-the-art Lecture), Stockholm Liver Week 2012, Stockholm, Sweden, 9-11 February 2012. 2012.
Fan S.T., Yang Z., Ho D.W.Y., Ng N.P., Yu W.C. and Wong J., Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study, Annals of Surgery. 2011, 254(4): 569-576.
Fan S.T., President, Hong Kong Society of Hepatobiliary and Pancreatic Surgery. 2012.
Fan S.T., Resection of liver tumor in cirrhotic patients (Invited Video Presentation), The 67th Annual Clinical Congress - Philippine College of Surgeons, Manila, Philippines, 4 - 7 December 2011. 2011.
Fan S.T., Reviewer, American Journal of Transplantation. 2012.
Fan S.T., Reviewer, Annals of Surgery. 2012.
Fan S.T., Reviewer, British Journal of Surgery. 2012.
Fan S.T., Reviewer, Digestive Surgery. 2012.
Fan S.T., Reviewer, Hepatobiliary and Pancreatic Diseases International. 2012.
Fan S.T., Reviewer, Hepatology International. 2012.
Fan S.T., Reviewer, Journal of American College of Surgeons. 2012.
Fan S.T., Reviewer, Journal of Nutrition & Metabolism. 2012.
Fan S.T., Reviewer, Liver Transplantation. 2012.
Fan S.T., Reviewer, PLoS ONE. 2012.
Fan S.T., Reviewer, Transplantation. 2012.
Fan S.T., Reviewer, World Journal of Gastroenterology. 2012.
Fan S.T., Right or left lobe or what? Living donor liver transplantation (Invited Lecture), Current Situation of Liver Disease in Mongolia International Conference, Ulaanbaatar, Mongolia, 23 September 2011. 2011.
Fan S.T., Staging and prognostication of liver cancer - changing from UICC 5th to the 7th edition (Invited Lecture), The 1st Symposium on Cancer Staging and Prognostication in China, Hong Kong, 10 September 2011. 2011.
Fan S.T., Technical innovations in liver transplantation (Abstract and Invited Lecture), The 3rd Biennial Congress of the Asian Pacific Hepato Pancreato Biliary Association, Melbourne, Australia, 27 - 30 September 2011. 2011.
Fan S.T., Technique of pancreaticojejunostomy in Whipple operation (Invited Video Presentation), The 67th Annual Clinical Congress - Philippine College of Surgeons, Manila, Philippines, 4 - 7 December 2011. 2011.
Fan S.T., Techniques to deal with variant donor anatomy in LDLT (Invited Lecture), The Internationl Liver Symposium, Delhi, India, 24-27 August 2011. 2011.
Fan S.T., To achieve cure: when to resect? when to transplant? (Invited Lecture), The 19th United European Gastroenterology Week, Stockholm, Sweden, 22 - 26 October 2011. 2011.
Fan S.T., Treasurer, Asian-Pacific Hepato-Pancreato-Biliary Association. 2012.
Fan S.T., Updates in liver transplantation – Hong Kong experience (Abstract and Keynote Lecture), State Key Laboratory for Liver Research Symposium 2011, Hong Kong, 24 September 2011. 2011.
Fan S.T., What is new in liver transplantation in Hong Kong (Abstract and Invited Lecture), The 21st World Congress of the International Association of Surgeons, Gastroenterologists and Oncologists, Tokyo, Japan, 9 - 12 November 2011. 2011.
Fan S.T., 肝癌肝移植基礎與臨床研究 (Invited Lecture), 浙江大學一院一千例肝移植慶典, 中國杭州, 2011年10月17日, 2011.
Fan S.T., 肝癌肝移植基礎與臨床研究 (Invited Lecture), 第十三屆全國肝癌學術會議, 中國重慶, 2011年9月15-17日, 2011.
Fan S.T., Yau T.C.C. and Poon R.T.P., 肝癌的綜合治療, 中華消化外科雜誌, 2011, 10: 241-246.
Fan S.T., 活體肝移植進展, 中華移植雜誌 (電子版), 2012, 6: 6-10.
Fan S.T., 影響肝臟移植受者長期存活的危險因素分析 (Invited Lecture), 臟器移植術後監測和數據網絡高峰論壇, 中國北京, 2011年12月16日, 2011.
Fatima S., Lee N.P.Y., Tsang F.H., Kolligs F.T., Ng I.O.L., Poon R.T.P., Fan S.T. and Luk J.M.C., Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway by influencing β-catenin in hepatocellular carcinoma, Oncogene. 2012, Epub on 2012-01-16.
Fung J.Y.Y., Chan S.C., Cheung C.K.Y., Chok K.S.H., Sharr W.W., Chan A.C.Y., Dai W.C., Cheung T.T., Fan S.T., Lai C.L., Yuen R.M.F. and Lo C.M., Entecavir Versus Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B., 18th Annual International Congress on ILTS Location: San Francisco, USA. May 16-19, 2012. Liver Transplantation.. 2012, 18 (supp 1): S124.
Fung J.Y.Y., Chan S.C., Yuen R.M.F., Lai C.L., Chok K.S.H., Sharr W.W., Dai W.C., Fan S.T. and Lo C.M., Long-term Outcome of Lamivudine Mono-prophylaxis After Liver Transplantation In Hepatitis B Patients , 62nd Annual Meeting Of The American-association-for-the-study-of-liver-diseases (AASLD) Location: San Francisco, USA. November 04-08, 2011. Hepatology . 2011, 54(Supp 1): 450A-450A.
Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Grant D., Fisher R.A., Abecassis M., McCaughan G., Wright L. and Fan S.T., Should the liver transplant criteria for hepatocellular carcinoma be different for deceased donation and living donation?, Liver Transplantation. 2011, 17(Suppl 2): S133-138.
Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Ivanovska I., Zhang C., Liu A.M.L., Wong K.F., Lee N.P.Y., Lewis P., Philippar U., Bansal D., Buser C., Scott M., Mao M., Poon R.T.P., Fan S.T., Cleary M.A., Luk J.M.C. and Dai H., Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma, PLoS One. 2011, 6(9): e24582.
Lam C.T., Yang Z., Ng N.P., Wan T.M.H., Lau J.C.S., Ho D.W.Y., Fan S.T. and Poon R.T.P., The potential role of CD44 in liver regeneration, The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.
Lam C.Y., Yip C.W., Poon T.C.W., Cheng C.K.C., Ng E.W.Y., Wong C.L., Cheung P.F.Y., Lai P.B.S., Ng I.O.L., Fan S.T. and Cheung S.T., Identification and characterization of tropomyosin 3 associated with granulin-epithelin precursor in human hepatocellular carcinoma, PLoS One. 2012, 7(7): e40324.
Lamb J.R., Zhang C., Xie T., Wang K., Zhang B., Hao K., Chudin E., Fraser H.B., Millstein J., Ferguson M., Suver C., Ivanovska I., Scott M., Poon R.T.P., Fan S.T., Yeung C., Lee N.P.Y. and Luk J.M.C., Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting, PLoS One. 2011, 6(7): e20090.
Lau C.K., Yang Z. and Fan S.T., Role of stem cells in normal liver and cancer, Anti-Cancer Agents in Medicinal Chemistry. 2011, 11(6): 522-528.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Li W., Jiang W., Zhou Z., Wang H. and Fan S.T., 中國器官獲取與移植監測網絡, 中華移植雜誌 (電子版), 2012, 6: 1-5.
Liu A.M.L., Yao T., Wang W., Wong K.F., Lee N.P.Y., Fan S.T., Poon R.T.P., Gao C. and Luk J.M.C., Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study, BMJ Open. 2012, 2(2): e000825.
Luk J.M.C., Burchard J., Zhang C., Liu A.M.L., Wong K.F., Shek H.P., Lee N.P.Y., Fan S.T., Poon R.T.P., Ivanovska I., Philippar U., Cleary M.A., Buser C.A., Shaw P.M., Lee C.N., Tenen D.G., Dai H. and Mao M., DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival, Journal of Biological Chemistry. 2011, 286(35): 30706-30713.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
Siriwardana R.C., Chan S.C., Chok K.S.H., Lo C.M. and Fan S.T., Effects of the liver volume and donor steatosis on errors in the estimated standard liver volume, Liver Transplantation. 2011, 17(12): 1437-1442.
Sung W.K., Zheng H., Li S., Chen R., Liu X., Li Y., Lee N.P.Y., Lee W.H., Wong K.F., Liu A.M.L., Poon R.T.P., Fan S.T., Chan K.L. and Luk J.M.C., Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma, Nature Genetics. 2012, 44(7): 765-769.
Wang X., Lo C.M. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver (Abstract), The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.
Wang X., Zhang W., Lui E.L.H., Zhu Y., Lu P., Yu X., Sun J., Yang S., Poon R.T.P. and Fan S.T., Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma, International Journal of Cancer. 2011, 131(3): E163-172.
Wong H., Tang Y.F., Yao T., Chiu J., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Poon R.T.P., Fan S.T. and Yau T.C.C., The outcomes and safety of single-agent sorafenib in the treatment of elderly patients with advanced hepatocellular carcinoma (HCC), Oncologist. 2011, 16(12): 1721-1728.
Yau T.C.C., Cheng P.N., Chan P., Chan W.Y.L., Chen L., Yuen J., Pang R.W.C., Fan S.T. and Poon R.T.P., A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma, Investigational New Drugs. 2012, Epub on 2012-03-17.
Yau T.C.C., Wong H., Chan P., Yao T., Pang R.W.C., Cheung T.T., Fan S.T. and Poon R.T.P., Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease, Investigational New Drugs. 2012, Epub on 2012-03-09.
Yau T.C.C., Yao T.J., Chan P., Wong H., Pang R.W.C., Fan S.T. and Poon R.T.P., The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib, Oncologist. 2011, Epub on 2011-09-01.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Fatima S

List of Research Outputs

Fatima S., Lee N.P.Y., Tsang F.H., Kolligs F.T., Ng I.O.L., Poon R.T.P., Fan S.T. and Luk J.M.C., Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway by influencing β-catenin in hepatocellular carcinoma, Oncogene. 2012, Epub on 2012-01-16.
Fatima S., Lee N.P.Y. and Luk J.M.C., Dickkopfs and Wnt/β-catenin signalling in liver cancer, World Journal of Clinical Oncology. 2011, 2(8): 311-325.
Fatima S., The role of dickkopfs (DKKs) in hepatocellular carcinoma: with a focus on DKK4, Thesis, Doctor of Philosophy, The University of Hong Kong. 2012.
Tung K.K., Mak K.M., Fatima S., Lo C.L.R., Zhao H., Zhang C., Dai H., Poon R.T.P., Yuen R.M.F., Lai C.L., Li J.J., Luk J.M.C. and Ng I.O.L., Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma, Liver International. 2011, 31(10): 1494-1504.


Researcher : Fatima S

List of Research Outputs

Fatima S., Lee N.P.Y., Tsang F.H., Kolligs F.T., Ng I.O.L., Poon R.T.P., Fan S.T. and Luk J.M.C., Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway by influencing β-catenin in hepatocellular carcinoma, Oncogene. 2012, Epub on 2012-01-16.
Fatima S., Lee N.P.Y. and Luk J.M.C., Dickkopfs and Wnt/β-catenin signalling in liver cancer, World Journal of Clinical Oncology. 2011, 2(8): 311-325.
Fatima S., The role of dickkopfs (DKKs) in hepatocellular carcinoma: with a focus on DKK4, Thesis, Doctor of Philosophy, The University of Hong Kong. 2012.
Tung K.K., Mak K.M., Fatima S., Lo C.L.R., Zhao H., Zhang C., Dai H., Poon R.T.P., Yuen R.M.F., Lai C.L., Li J.J., Luk J.M.C. and Ng I.O.L., Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma, Liver International. 2011, 31(10): 1494-1504.


Researcher : Fu KKF

List of Research Outputs

Fu K.K.F., Editor-in-Chief, Certificate Course on Mangement of Common Urological Problems for Primary Healthcare Providers 2011 (co-organized by HKMA Central, Western, Southern Community Network and Department of Surgery of Queen Mary Hospital). 2011.
Ng A.T.L., Fu K.K.F. and Wong B.T.H., Emergency percutaneous nephrostomy in supine position under local anesthesia (Poster), The 31st Congress of the Societe International d’Urologie, Berlin, Germany, 16 - 20 October 2011.
Ng A.T.L., Fu K.K.F. and Ho K.L., PCNL trajectory to predict success in supine PCNL: a novel concept (Abstract), The 29th World Congress of Endourology & SEL, Kyoto, Japan, 30 November – 3 December 2011. Journal of Endourology. 2011, 25(Suppl 1): A145.
Ng A.T.L., Fu K.K.F., Ho K.L. and Yiu M.K., PCNL trajectory: a novel concept to predict success in supine PCNL (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S9-S10.
Ng A.T.L., Fu K.K.F., Wong B.T.H., Ho K.L. and Tam P.C., Simultaneous antegrade and retrograde approach for complex upper tract stones in modified supine valdivia position (Poster), The 31st Congress of the Societe International d’Urologie, Berlin, Germany, 16 - 20 October 2011.
Tsang C.F., Fu K.K.F., Ng S.L., Cheung M.H., Ng A.T.L., Ho B.S.H., Ho K.L. and Yiu M.K., The relationship between renal stone excursion distance and body build during ESWL (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S6-S7.
Wong K.W., Wong C.W.S., Chiang S.C., Tsang C.F., Li S.K., Chiu Y., Wong M.H., Fu K.K.F. and Ho K.L., A local survey on skeletal related complications in patients with carcinoma of prostate having hormonal therapy (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S8-S9.


Researcher : Fung CF

List of Research Outputs

Pu J.K.S., Chan R.T.T., Ng G.K.B., Leung G.K.K., Hung K.N. and Fung C.F., Using bevacizumab in the fight against malignant glioma: first results in Asian patients, Hong Kong Medical Journal. 2011, 17(4): 274-279.


Researcher : Gandhi A

Project Title:Self-assembling peptide nanofiber scaffold (SAPNS) as a potential neuro-regenerative biomaterial in surgically induced brain injury.
Investigator(s):Leung GKK, Wu W
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:02/2011


Project Title:16th Annual Scientific Meeting & Education Day of the Society for Neuro-Oncology Acquired temozolomide resistance in human malignant gliomas: a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide.
Investigator(s):Leung GKK
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2011
Completion Date:11/2011


List of Research Outputs



Researcher : Gao W

Project Title:Identification of microRNAs associated with cisplatin-resistance in nasopharyngeal carcinoma
Investigator(s):Gao W, Wong STS
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:02/2012


List of Research Outputs

Gao W., Chan Y.W., Wei W.I. and Wong S.T.S., Anti-Cancer effects of curcumin on head and neck cancer, Anticancer Agents in Medical Chemistry. 2012, Epub on 2 May 2012.
Gao W., Li J.Z., Ho W.K., Chan Y.W. and Wong S.T.S., Biomarkers for use in monitoring responses of nasopharyngeal carcinoma cells to Ionizing radiation, Sensors. 2012, 12(7): 8832-8846.
Tsang R.K.Y., Tang W.Y., Gao W., Ho W.K., Chan Y.W., Wei W.I. and Wong S.T.S., Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10, Cancer Investigation. 2012, 30(7): 503-512.
Tsang R.K.Y., Gao W. and Wong S.T.S., Surgical treatment of the squamous cell carcinoma of the tongue and the effect on speech and swallowing, In: Kato H. and Shimizu T. (eds.), Tongue: Anatomy, Kinematics and Diseases (Human Anatomy and Physiology). Hauppauge, New York, Nova Science, 2012, 1-16.
Wong S.T.S., Gao W., Li Z., Chan Y.W. and Ho W.K., Epigenetic dysregulation in laryngeal squamous cell carcinoma, Journal of Oncology. 2012, 2012: 739461.
Wong S.T.S., Gao W., Ho W.K., Chan Y.W. and Tsang R.K.Y., MicroRNA dysregulation in squamous cell carcinoma of head and neck, In: Li X. (ed.), Squamous Cell Carcinoma. Rijeka, Croatia, Intech, 2011, 255-280.


Researcher : Garcia-Barcelo MM

Project Title:Identification of functional variants in Neuregulin-1 (NRG1), a newly discovered Hirschsprungs disease gene
Investigator(s):Garcia-Barcelo MM, Cherny SS, Sham PC, Tam PKH
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2009
Completion Date:09/2011


Project Title:Functional characterization of the V226L, H347Y, and P356L NRG1 mutations identified in Hirschsprung's disease patients
Investigator(s):Garcia-Barcelo MM, Ngan ESW
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2010
Completion Date:05/2012


Project Title:Investigation of structural variations in Caudal Regression Syndrome Patients
Investigator(s):Garcia-Barcelo MM, Tam PKH, Cherny SS
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2011


Project Title:61st Annual Meeting of the American Society of Human Genetics Genome-wide copy number analysis uncovers a new HSCR gene: NRG3
Investigator(s):Garcia-Barcelo MM
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2011
Completion Date:10/2011


Project Title:Whole-exome sequencing to identify genes underlying Caudal Regression Syndrome
Investigator(s):Garcia-Barcelo MM, Cherny SS, Sham PC, Tam PKH
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2011


Project Title:Investigation of coding sequence mutations and structural variations in SHAH-WAARDENBURG SYNDROME: study of a 3 generation family
Investigator(s):Garcia-Barcelo MM, Tam PKH
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Cherny S.S., Garcia-Barcelo M.M., Leon Y.Y., So M.T., Sham P.C. and Tam P.K.H., RET mutational spectrum in Hirschsprungs disease: Evaluation of 601 Chinese patients, 12th International Congress of Human Genetics. 2011, 790.
Cui L., Wong E.H.M., Zhu J., Almeida M.F. .D.E., Tam P.K.H. and Garcia-Barcelo M.M., Genetic study of a family segregating Shah-Waardenburg syndrome, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
Garcia-Barcelo M.M., Genetic studies of Hirschsprung disease, Harbin Children Hospital, Harbin, China, 9 January 2012. 2012.
Garcia-Barcelo M.M., Genetic studies of Hirschsprung disease, Shandong University Affiliated 2nd Hospital, Jinan, China. 2011.
Garcia-Barcelo M.M., Genetic studies of congeniotal malformations involving the digestive system, Hong Kong University-McGill Symposium, Hong Kong. 2012.
Garcia-Barcelo M.M., Tam P.K.H., Cherny S.S. and Sham P.C., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, The 61st Annual Meeting of the American Society of Human Genetics, Montreal, Canada, 11 - 15 October 2011.
Garcia-Barcelo M.M. and Tam P.K.H., Identification of ADD3 as a susceptible gene for biliary atresia: evidence from genetic fine mapping (Oral presentation), The 58th International Conference of British Association of Paediatric Surgeons, Belfast, U.K., 19 - 22 July 2011.
Garcia-Barcelo M.M., Reviewer (2012), National Medical Research Council, Singapore. 2012.
Garcia-Barcelo M.M., Reviewer for Research Grant, National Medical Research Council, Singapore. 2011.
Garcia-Barcelo M.M., Reviewer for Research Grant, South African Medical Research Council, 2012. 2012.
Garcia-Barcelo M.M., Reviewer of two projects (2012), Italian Ministry for Education, University and Research. 2012.
Leon Y.Y., So M.T., Lui V.C.H., Hofstra R.M.W., Tam P.K.H., Ngan E.S.W. and Garcia-Barcelo M.M., Functional analyses of RET mutations in Chinese Hirschsprung disease patients, Birth Defects Research (Part A): Clinical and Molecular Teratology. 2012, 94(1): 47-51.
Li R., Yang W., Zhang J., Hirankarn N., Pan H.F., Mok C.C., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Lee T.L., Ho M.H.K., Lee P.P.W., Chan T.M., Wong W.H.S., Wong C.M., Ng I.O.L., Yang J., Li P.H., Zhang Y., Zhang L., Li W., Baum L., Kwan P., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S., Shen N., Lau Y.L. and Ye D.Q., Association of CD247 with systemic lupus erythematosus in Asian populations, Lupus. 2012, 21(1): 75-83.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., Hedgehog-Notch induced premature gliogenesis: a new disease mechanism for Hirschsprung's disease., The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
Ngan E.S.W., Garcia-Barcelo M.M., Yip B.H.K., Poon P.C., Lau C.S.T., Kwok K.M., Sat E.W.Y., Sham M.H., Wong K.K.Y., Wainwright B.J., Cherny S.S., Hui C.C., Sham P.C., Lui V.C.H. and Tam P.K.H., Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung’s disease in mice and humans, Journal of Clinical Investigation. 2011, 121(9): 3467-3478.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tam P.K.H., Garcia-Barcelo M.M., Tang S.M., Yeung M.Y., Cheng G., Wong E.H.M., Cui L., Cherny S.S. and Sham P.C., Genetic studies of congenital gastrointestinal diseases (Invited Lecture), The 13th SCBA (Society of Chinese Bioscientists in America) International Symposium, Sun Yat-sen University, Guangzhou, China, 25 - 19 July 2011. 2011.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
Waye M.M.Y., Baum L., Boyde T.R.C., Chan K.K.K., Cherny S.S., Choy F., Garcia-Barcelo M.M., Gong Z., Kagawa H., Kotaka M., Lee C.Y., Lee S.M.Y., Li H.Y., Meng H., Ng R.K., Ng T.B., Pollard J., Qi R., Shen D.W., Tam S.S.W., Tsang F.S.Y., Wasylyk B., Xue H. and Siu C.O., Journal of Biochemistry and Molecular Biology in the Post Genomic Era. 2011.
Waye M.M.Y., Baum L., Boyde T.R.C., Chan K.K.K., Cherny S.S., Choy F., Garcia-Barcelo M.M., Gong Z., Kagawa H., Kotaka M., Lee C.Y., Lee S.M.Y., Li H.Y., Meng H., Ng R.K., Ng T.B., Pollard J., Qi R., Shen D.W., Tam S.S.W., Tsang F.S.Y., Wasylyk B., Xue H. and Siu C.O., Journal of Biochemistry and Molecular Biology in the Post Genomic Era. 2011.
Zhu J., Garcia-Barcelo M.M., Tam P.K.H. and Lui V.C.H., RET transcriptional regulation by HOXB5 in Hirschsprung's disease, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.


Researcher : Geng W

List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Geng W

List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Guo D

List of Research Outputs

Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.


Researcher : He GW

Project Title:1999 American Physiological Society Conference: Biology of Potassium Channels (From Molecules to Disease) Role of K+ Channels in Endothelum-derived Hyperpolarizing Factor (EDHF)-mediated Function in Coronary Microartery 2) Reduced Conductance of Kca and K ATP Channels by University of Wisconsin Solution (UWS) in Coronary Microartery
Investigator(s):He G
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/1999




Researcher : Ho CWA

List of Research Outputs

Chung J.C.K., Tsang R.K.Y., To V.S.H., Ho C.W.A., Chan Y.W., Ho W.K. and Wei W.I., Secondary head and neck cancer in patients with history of haematological malignancy, Head & Neck. 2012, Epub on 15 May 2012.
Ho C.W.A., Lee V.H.F., To V.S.H., Kwong D.L.W. and Wei W.I., Natural course and tumor doubling time of nasopharyngeal carcinoma. A study of 15 patients, Oral oncology. Elsevier, 2011, 47(8): 742-6.


Researcher : Ho DWY

List of Research Outputs

Fan S.T., Yang Z., Ho D.W.Y., Ng N.P., Yu W.C. and Wong J., Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study, Annals of Surgery. 2011, 254(4): 569-576.
Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Lam C.T., Yang Z., Ng N.P., Wan T.M.H., Lau J.C.S., Ho D.W.Y., Fan S.T. and Poon R.T.P., The potential role of CD44 in liver regeneration, The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.


Researcher : Ho JCY

Project Title:Differentiation and Isolation of Endothelial Cells from Human Induced Pluripotent Stem Cells
Investigator(s):Ho JCY, Tse HF, Lai KWH
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:10/2010
Completion Date:09/2011


List of Research Outputs

Cheung P.F.Y., Cheng C.K.C., Wong C.L., Ho J.C.Y., Yip C.W., Lui V.C.H., Cheung A.N.Y., Fan S.T. and Cheung S.T., Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells, PLoS One. 2011, 6(12): e28246.
Leung G.K.K., Ho J.C.Y. and Pu J.K.S., Pituitary enlargement in spontaneous intracranial hypotension - a diagnostic pitfall, Acta Neurochirurgica(Wien). 2011, 153(12): 2445-2446.


Researcher : Ho JWC

Project Title:The Hereditary Gastrointestinal Cancer Registry - a programme for the people of Hong Kong
Investigator(s):Ho JWC, Yuen ST, Chung LP, Kwan KYM
Department:Surgery
Source(s) of Funding:Terry Fox Fellowship
Start Date:06/2000


Project Title:A Genome-Wide Association Study on the Predisposition to Colorectal Cancer in the Han Chinese Population in Hong Kong
Investigator(s):Ho JWC, Sham PC
Department:Surgery
Source(s) of Funding:Michael and Betty Kadoorie Cancer Genetics Research Programme (MBKCGRP) II
Start Date:01/2008


Project Title:The acceptability and feasibility of a diet and physical activity intervention to prevent recurrence in colorectal cancer survivors
Investigator(s):Ho JWC, Leung SSK, Lee AM, Macfarlane DJ, Fong DYT
Department:Surgery
Source(s) of Funding:World Cancer Research Fund - General Award
Start Date:03/2010


List of Research Outputs

Burn J., Gerdes A.M., Macrae F., Mecklin J.P., Moeslein G., Olschwang S., Eccles D., Evans D.G., Maher E.R., Bertario L., Bisgaard M.L., Duniop M.G., Ho J.W.C., Hodgson S.V., Lindblom A., Lubinski J., Morrison P.J. and CAPP2 Investigators -., Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial, Lancet. 2011, 378(9809): 2081-2087.
Fong D.Y.T., Ho J.W.C., Hui P.H., Lee A.M., Macfarlane D.J., Leung S.S.K., Cerin E., Chan W.Y.Y., Leung I.P.F., Lam S.H.S., Taylor A.J. and Cheng K.K., Physical activity for cancer survivors: meta-analysis of randomised controlled trials., British Medical Journal. 2012, 344: e70.
Ho S.M.Y., Ho J.W.C., Pau B.K.Y., Hui B.P.H., Wong R.S.M. and Chu A.T.W., Hope-based intervention for individuals susceptible to colorectal cancer: a pilot study, Familial Cancer. 2012, Epub ahead of print.
Houlston R.S., Ho J.W.C. and Members of COGENT , COGENT (COlorectal cancer GENeTics) revisited , Mutagenesis. 2012, 27(2): 143-151.


Researcher : Ho KL

List of Research Outputs

Ng A.T.L., Fu K.K.F. and Ho K.L., PCNL trajectory to predict success in supine PCNL: a novel concept (Abstract), The 29th World Congress of Endourology & SEL, Kyoto, Japan, 30 November – 3 December 2011. Journal of Endourology. 2011, 25(Suppl 1): A145.
Ng A.T.L., Fu K.K.F., Ho K.L. and Yiu M.K., PCNL trajectory: a novel concept to predict success in supine PCNL (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S9-S10.
Ng A.T.L., Fu K.K.F., Wong B.T.H., Ho K.L. and Tam P.C., Simultaneous antegrade and retrograde approach for complex upper tract stones in modified supine valdivia position (Poster), The 31st Congress of the Societe International d’Urologie, Berlin, Germany, 16 - 20 October 2011.
Tsang C.F., Fu K.K.F., Ng S.L., Cheung M.H., Ng A.T.L., Ho B.S.H., Ho K.L. and Yiu M.K., The relationship between renal stone excursion distance and body build during ESWL (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S6-S7.
Wong K.W., Wong C.W.S., Chiang S.C., Tsang C.F., Li S.K., Chiu Y., Wong M.H., Fu K.K.F. and Ho K.L., A local survey on skeletal related complications in patients with carcinoma of prostate having hormonal therapy (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S8-S9.
Yip S.K.H., Yee C.H., Ng C.F., Lam N.Y., Ho K.L., Ma W.K., Li C.M., Hou S.M., Tam P.C., Yiu M.K. and Fan C.W., Robot-assisted radical prostatectomy in Hong Kong: a review of 235 cases, Journal of Endourology. 2012, 26(3): 258-263.


Researcher : Ho WK

Project Title:Effect of chemotherapy on cochlear function
Investigator(s):Ho WK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:06/1996


Project Title:Evaluation of a novel electronic device in screening for obstructive sleep syndrome in snore
Investigator(s):Ho WK, Chung KF
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:03/2002


Project Title:Study of changes in upper airway pressure in patients before and after upper airway surgery for sleep-related breathing disorders: identification of levels of collapse and prediction of surgical response
Investigator(s):Ho WK, Wei WI
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2003


List of Research Outputs

Chung J.C.K. and Ho W.K., A large cervical osteophyte presenting as an oropharyngeal mass, Ear, Nose & Throat Journal. 2011, 90(10): 476-478.
Chung J.C.K., Tsang R.K.Y., To V.S.H., Ho C.W.A., Chan Y.W., Ho W.K. and Wei W.I., Secondary head and neck cancer in patients with history of haematological malignancy, Head & Neck. 2012, Epub on 15 May 2012.
Gao W., Li J.Z., Ho W.K., Chan Y.W. and Wong S.T.S., Biomarkers for use in monitoring responses of nasopharyngeal carcinoma cells to Ionizing radiation, Sensors. 2012, 12(7): 8832-8846.
Lam W.K., Tsang R.K.Y., Leung G.K.K. and Ho W.K., Management of profuse epistaxis in post-irradiated nasopharyngeal carcinoma patients, The 15th Asian Research Symposium on Rhinology, Singapore, 24 - 26 May 2012.
Tsang R.K.Y., Ho W.K. and Wei W.I., Combined robotic and endoscopic nasopharyngectomy for recurrent nasopharyngeal cancer, The 15th Asian Research Symposium in Rhinology, Singapore, 24 - 26 May 2012.
Tsang R.K.Y., Tang W.Y., Gao W., Ho W.K., Chan Y.W., Wei W.I. and Wong S.T.S., Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10, Cancer Investigation. 2012, 30(7): 503-512.
Tsang R.K.Y. and Ho W.K., Endoscopic treatment of eye diseases, Hong Kong Surgical Forum - Summer, The University of Hong Kong, Hong Kong, 16 July 2011. 2011.
Wong B.Y.H., Hui T., Lee S.L., Ho W.K. and Wei W.I., Stridor in Asian Infants: assessment and treatment, ISRN Otolaryngology. 2011, 2012.
Wong S.T.S., Gao W., Li Z., Chan Y.W. and Ho W.K., Epigenetic dysregulation in laryngeal squamous cell carcinoma, Journal of Oncology. 2012, 2012: 739461.
Wong S.T.S., Gao W., Ho W.K., Chan Y.W. and Tsang R.K.Y., MicroRNA dysregulation in squamous cell carcinoma of head and neck, In: Li X. (ed.), Squamous Cell Carcinoma. Rijeka, Croatia, Intech, 2011, 255-280.


Researcher : Hui KC

List of Research Outputs

Hui K.C., Lai K.Y., Chan K.W., Luk J.M., Lee N.P.Y., Chung Y., Cheung L.C., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Clinical correlation of nuclear survivin in esophageal squamous cell carcinoma, Med Oncol.. 2012, [Epub ahead of print].
Hui K.C., Chan K.W., Luk J.M.C., Lee N.P.Y., Chung M.F.Y., Cheung C.M., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Cytoplasmic Forkhead Box M1 (FoxM1) in esophageal squamous cell carcinoma significantly correlates with pathological disease stage, World Journal of Surgery. 2012, 36(1): 90-97.


Researcher : Hui PH

List of Research Outputs

Fong D.Y.T., Ho J.W.C., Hui P.H., Lee A.M., Macfarlane D.J., Leung S.S.K., Cerin E., Chan W.Y.Y., Leung I.P.F., Lam S.H.S., Taylor A.J. and Cheng K.K., Physical activity for cancer survivors: meta-analysis of randomised controlled trials., British Medical Journal. 2012, 344: e70.


Researcher : Hung KN

List of Research Outputs

Pu J.K.S., Chan R.T.T., Ng G.K.B., Leung G.K.K., Hung K.N. and Fung C.F., Using bevacizumab in the fight against malignant glioma: first results in Asian patients, Hong Kong Medical Journal. 2011, 17(4): 274-279.
Taw B.B.T., Lam A.C.S., Hung K.N., Lui W.M., Leung G.K.K. and Ho F.L.Y., Functional survival after acute care for severe head injury at a designated trauma center in Hong Kong, Asian Journal of Surgery. 2012, Epub 06-06-2012.
Taw B.T., Lee V.H.F., Hung K.N., Ng C.Y. and Lui W.M., The efficacy and safety of LINAC stereotactic radiosurgery booster after whole brain radiotherapy for cerebral metastases , XXth ESSFN conference in 2011.


Researcher : Kam KM

List of Research Outputs

Kam K.M., Expression of engrailed-Hoxb5 transcriptional repressor by Wnt1-Cre produces neurocristopathies in mice, Thesis, Doctor of Philosophy, The University of Hong Kong. 2012.
Kam K.M., Lee K.Y., Tam P.K.H. and Lui V.C.H., Generation of NSE-MerCreMer transgenic mice with tamoxifen inducible Cre activity in neurons, PLoS One. 2012, 7(5): e35799.
Kam K.M., Cheung M.C.H., Tam P.K.H. and Lui V.C.H., Hoxb5 trans-activates Sox9 and regulates trunk neural crest cell development, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.


Researcher : Kam KM

List of Research Outputs

Kam K.M., Expression of engrailed-Hoxb5 transcriptional repressor by Wnt1-Cre produces neurocristopathies in mice, Thesis, Doctor of Philosophy, The University of Hong Kong. 2012.
Kam K.M., Lee K.Y., Tam P.K.H. and Lui V.C.H., Generation of NSE-MerCreMer transgenic mice with tamoxifen inducible Cre activity in neurons, PLoS One. 2012, 7(5): e35799.
Kam K.M., Cheung M.C.H., Tam P.K.H. and Lui V.C.H., Hoxb5 trans-activates Sox9 and regulates trunk neural crest cell development, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.


Researcher : Kwok KM

List of Research Outputs

Chan W.M., Lau L.S., Kwok K.M., Law W.L., Ho J.C.M., Chu K.M. and Poon R.T.P., A randomized, double-blind, placebo-controlled, ascending dose infusion trial of the pharmacokinetics of recombinant human Gelsolin in patients with decreased natural Gelsolin levels, American Thoracic Society International Conference, Denver, U.S.A., 13 - 18 May 2011. American Journal of Respiratory and Critical Care Medicine. 2011, 183: A5601.
Ngan E.S.W., Garcia-Barcelo M.M., Yip B.H.K., Poon P.C., Lau C.S.T., Kwok K.M., Sat E.W.Y., Sham M.H., Wong K.K.Y., Wainwright B.J., Cherny S.S., Hui C.C., Sham P.C., Lui V.C.H. and Tam P.K.H., Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung’s disease in mice and humans, Journal of Clinical Investigation. 2011, 121(9): 3467-3478.


Researcher : Kwong A

Project Title:An investigation into the presence of human papilloma virus (HPV) in breast cancer specimens from Hong Kong patients
Investigator(s):Kwong A, Ng EKO
Department:Surgery
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Mini Grants
Start Date:10/2011


List of Research Outputs

Antoniou A.C., Kuchenbaecker K.B., Soucy P., Beesley J., Chen X., McGuffog L., Lee A., Barrowdale D., Healey S., Sinilnikova O.M., Caligo M.A., SWE-BRCA , Loman N., Harbst K., Lindblom A., Arver B., Rosenquist R., Karission P., Nathanson K., Domehek S., Rebbeck T., Jabubowska A., Lubinski J., Jaworska K., Durda K., Zlowowcka-Perlowska E., Osorio A., Duran M., Andres R., Benitez J., Hamann U., Hogervorst F.B., van O T.A., Verhoef S., Meijers-Heijboer H.E.J., Wijnen J., Gomez Garcia E.B., Ligtenberg M.J., Kriege M., Collee J.M., Ausems M.G.E.M., Oosterwijk J.C., HEBON , EMBRACE , Peock S., Frost D., Ellis S.D., Platte R., Fineberg E., Gareth Evans D., Lalloo F., Jacobs C., Eeles R., Adlard J., Davidson R., Cole T., Cook J., Paterson J., Douglas F., Brewer C., Hodgson S., Morrison P.J., Walker L., Rogers M.T., Donaldson A., Dorkins H., Godwin A.K., Bove B., Stoppa-Lyonnet D., Houdayer C., Buecher B., de Pauw A., Mazoyer S., Calender A., Leone M., Bressac-de Paillerets B., Caron O., Sobol H., Frenay M., Prieur F., Ferrer S.F., Mortemousque I., GEMO Study Collaborators , Buys S., Daly M., Miron A., Terry M.B., Hopper J.L., John E.M., Southey M., Goldgar D., Singer C.F., Fint-Retter A., Tea M.-.K., Kaulich D.G., Hansen T.V.O., Nielsen F.C., Barkardottir R.B., Gaudet M., Kirchhoff T., Joseph V., Dutra-Clarke A., Offit K., Piedmonte M., Kirk J., Cohn D., Hurtea J., Byron J., Fiorica J., Tolad A.E., Montagna M., Oliani C., Imyanitov E., Isaacs C., Tihomirova L., Blanco I., Lazaro C., Teule A., Del Valle J., Gayther S.A., Odunsi K., Gross J., Karlan B.Y., Olah E., Teo S.-.H., Ganz P.A., Ganz P.A., Beattie M.S., Dorfling C.M., van Resburg E.J., Diez O., Kwong A., Schmutzler R.K., Wappenschmidt B., Engel C., Meindl A., Ditsch N., Arnold N., Heidemann S., Niederacher D., Preister-Adams S., Gadzicki D., Varon-Mateeva R., Deissler H., Gehrig A., Sutter C., Kast K., Fiebig B., Schafer D., Caldes T., de la Hoya M., Nevanlinna H., Muranen T.A., Lesperance B., Spurdle A.B., kConFab Investigators , Neuhausen S.L., Ding Y.C., Wang X., Fredericksen Z., Pankratz V.S., Lindor N.M., Peterlongo P., Manoukian S., Peissel B., Zaffaroni D., Bonanni B., Bernard L., Dolcetti R., Papi L., Ottini L., Radice P., Greene M.H., Loud J.T., Andrulis I.L., Ozcelik H., Mulligan A.M., Glendon G., Thomassen M., Gerdes A.-.M., Jensen U.B., Skytte A.-.B., Kruse T.A., Chenevix-Trench G., Couch F.J., Simard J., Easton D.F. and on behalf of CIMBA , Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutatino carriers, Breast Cancer Research. 2012, 14(1): R33 (Epub ahead of print).
Au A.H.Y., Lam W.W.T., Tsang J.W.H., Yau T.K., Soong S.I., Yeo W., Suen J., Ho W.M., Wong K.Y., Kwong A., Suen T.K.D., Sze W.K., Ng A., Girgis A. and Fielding R., Support care needs in Hong Kong Chinese women confronting advanced breast cancer, Psychooncology. 2012.
Au H.Y.A., Lam W.W.T., Tsang J.W.H., Yau T.K., Yau T.K., Soong I., Yeo W., Suen J., Ho W.M., Wong K.Y., Kwong A., Suen D.T.K., Sze W.K., Ng A., Girgis A. and Fielding R., Change patterns in supportive care needs among women diagnosed with advanced breast cancer (abstract), 18th Hong Kong International Cancer Congress, 3-5 November 2011, Hong Kong. Hong Kong, Centre for Cancer Research, University of Hong Kong, 2011, A76.
Au H.Y.A., Lam W.W.T., Tsang J.W.H., Yau T.K., Soong I., Yeo W., Suen J., Ho W.M., Wong K.Y., Kwong A., Suen D.T.K., Sze W.K., Ng A., Girgis A. and Fielding R., Change patterns of supportive care needs among women diagnosed with advanced breast cancer (abstract and powerpoint presentation), 18th Hong Kong International Cancer Congress, 3-5 November 2011, Hong Kong. Hong Kong, Centre for Cancer Research, University of Hong Kong, 2011.
Au H.Y.A., Lam W.W.T., Chan M.C.M., Or A.Y.M., Kwong A., Suen D.T.K., Wong A.L., Juraskova I., Wong W.T.T. and Fielding R., Development and pilot-testing of a decision aid for use among Chinese women facing breast cancer surgery, Health Expectations. 2011, 14(4): 405-416.
Au H.Y.A., Lam W.W.T., Cheung O.K.Y., Tsang J.W.H., Yau T.K., Soong I., Yeo W., Suen J., Ho W.M., Wong K.Y., Kwong A., Suen D.T.K., Sze W.K., Ng A., Girgis A. and Fielding R., Unmet supportive care needs in Hong Kong Chinese women confronting advanced breast cancer (abstract and poster presentations), Psycho-Oncology Supplement: Abstracts for the 13th World Congress of Psycho-Oncology, 16–20 October 2011, Antalya, Turkey. 2011, 20(Suppl 2): 198-199.
Au H.Y.A., Lam W.W.T., Kwong A., Suen D.T.K., Tsang J.W.H., Yeo W., Suen J., Ho W.M., Yau T.K., Soong I., Wong K.Y., Sze W.K., Ng A., Girgis A. and Fielding R., Validation of the Chinese version of the short-form supportive Care Needs Survey Questionnaire (SCNS-SF34-C), Psycho-Oncology. 2011, 20(12): 1292-1300.
Baselga J., Bradbury I., Eidtmann H., Di Cosimo S., de Azambuja E., Aura C., Gomez H., Dinh P., Fauria K., Van Dooren V., Aktan G., Goldhirsch A., Chang T.W., Horvath Z., Coccia-Portugal M., Domont J., Tseng L.M., Kunz G., Sohn J.H., Semiglazov V., Lerzo G., Palacova M., Probachai V., Pusztai L., Untch M., Gelber R.D., Piccart-Gebhart M., NeoALTTO Study Team and Kwong A., Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial, Lancet. 2012, 379(9816): 633-640.
Bolton K.L., Chenevix-Trench G., Goh C., Sadetzki S., Ramus S.J., Kartan B.Y., Lambrechts D., Despierre E., Barrowdale D., McGuffog L., Healey S., Easton D.F., Sinilnikova O., Benitez J., Garcia M.J., Neuhausen S., Gail M.H., Hartge P., Peock S., Frost D., Evans D.G., Eeles R., Godwin A.K., Daly M.B., Kwong A., Ma E.S., Lazaro C., Blanco I., Montagna M., D'Andrea E., Nicoletto M.O., Johnatty S.E., Kjaer S.K., Jensen A., Hogdall E., Goode E.L., Fridley B.L., Loud J.T., Greene M.H., Mai P.L., Chetrit A., Lubin F., Hirsh-Yechezkel G., Glendon G., Andrulis I.L., Toland A.E., Senter L., Gore M.E., Gourley C., Michie C.O., Song H., Tyrer J., Whittemore A.S., McGuire V., Sieh W., Kristoffersson U., Olsson H., Borg A., Levine D.A., Steele L., Beattie M.S., Chan S., Nussbaum R.L., Moysich K.B., Gross J., Cass I., Walsh C., Li A.J., Leuchter R., Gordon O., Garcia-Closas M., Gayther S.A., Chanock S.J., Antoniou A.C. and Pharoah P.D., Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer, JAMA. 2012, 307(4): 382-390.
Couch F.J., Gaudet M.M., Antoniou A.C., Ramus S.J., Kuchenbaecker K.B., Soucy P., Beesley J., Chen X., Wang X., Kirchhoff T., McGuffog L., Barrowdale D., Lee A., Healey S., Sinilnikova O.M., Andrulis I.L., Ozcelik H., Mulligan A.M., OCGN , Thomassen M., Gerdes A.-.M., Jensen U.B., Skytte A.-.B., Kruse T.A., Caligo M.A., SWE-BRCA , von Wachenfeldt A., Barbany-Bustinza G., Loman N., Soller M., Ehrencrona H., Karlsson P., Nathanson K., Rebbeck T., Domchek25 S., Jakubowska A., Lubinski J., Jaworska K., Durda K., Zlowocka E., Huzarski T., Byrski T., Gronwald J., Cybulski C., Gorski B., Osorio A., Duran M., Tejada M.I., Benitez J., Hamann U., Hogervorst F.B.L., van Os T.A., van Leeuwen F.E., Meijers-Heijboer H.E.J., Wijnen J., Blok M.J., Kets M., Hooning M.J., Oldenburg R.A., Ausems M.G.E.M., HEBON34 , EMBRACE44 , Peock44 S., Frost44 D., Ellis S.D., Platte R., Fineberg E., Gareth Evans D., Jacobs C., Eeles R., Adlard J., Davidson R., Eccles D., Cole T., Cook J., Paterson J., Brewer C., Douglas F., Hodgson S., Morrison P.J., Walker L., Porteous M.E., John Kennedy M., Side L.C., Bove B., Godwin A.K., GEMO Study Collaborators , STOPPA-lYONNET65, 66, 67 D., Fassy-Colcombet M., Castera L., Cornelis F., Mazoyer S., Leone M., Boutry-Kryza N., Bressac-de Paillerets B., Caron O., Pujol P., Coupier I., Delmate C., Akloul L., Lynch H.T., Synder C.L., Buys S.S., Daly M.B., Terry M.B., Chung W., John E.M., Miron A., Southey M.C., Hopper J.L., Goldgar D., Singer C.F., Rappaport C., Tea M. .M.-.K., Retter A.-.F., Hansen V.O., Nielsen F.C., Arason A., Vijai J., Shah S., Sarrel K., Robson M., Piedmonte M., Philips K., Basil J., Rubinstein W., Boggess J., Wakeley K., Toland A.E., Montagna M., Agata S., Imyanitov E., Issacs C., Janavicius R., Lazaro C., Blanco I., Feliubadalo L., Brunet J., Gayther S.A., Pharoah P.P.D., Odunsi K., Karlan B.Y., Walsh C.S., Olah E., Teo S.H., Ganz P.A., Beattie M.S., van Rensburg E.J., Dofling C.M., Diez O., Kwong A., Schmutzler R.K., Wappenschmidt B., Engel C., Meindl A., Ditsch N., Arnold N., Beidemann S., Niederacher D., Preister-Adams S., Kast K., Gadzicki D., Varon-Mateeva R., Diessler H., Gehrig A., Sutter C., Kast K., Fiebig B., Heinritz W., Caldes T., de la Hoya M., Kuranen A., Nevanlinna H., Tischkowitz M., Spurdle A.B., kConFab investigators , Neuhausen S.L., ChuDing Y., Lindor N., Fredeericksen Z., Shane Pankratz V., Peterlongo P., Manoukian S., Peissel B., Zaffaroni D., Barlie M., Bernard L., Viel A., Giannini G., Varesco L., Radice P., Greene M.H., Mai P.L., Easton D.F. and Chenevix-Trench6 , Offit K., Simard J., Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers, Cancer Epidemiology, Biomarkers and Prevention. 2012, Epub ahead of print.
Kwong A. and Chu A.T.W., A retrospective study on surveillance behaviours and prophylasix after genetic testing for hereditary breast and ovarian cancer among high-risk Chinese females, The San Antonio Breast Cancer Symposium, San Antonio, California, U.S.A., 6 - 10 December 2011.
Kwong A., Wong C.H., Suen D.T.K., Co M., Kurian A.W., West D.W. and Ford J.M., Accuracy of BRCA1/2 mutation prediction models for different ethnicities and genders: experience in a Southern Chinese Cohort, World Journal of Surgery. 2012, Epub ahead of print.
Kwong A., Mang O.W., Wong H.N., Chau W.W., Law S.C. and Hong Kong Breast Cancer Research Group , Breast cancer in Hong Kong, Southern China: the first population-based analysis of epidemiological characteristics, stage-specific, cancer-specific, and disease-free survival in breast cancer patients: 1997-2001, Annals of Surgical Oncology. 2011, 18(11): 3072-3078.
Kwong A., Epidemiology of breast cancer in Hong Kong: a review 1997-2001, Round Asia Oncology Forum, Shanghai, China, 26 - 28 August 2011. 2011.
Kwong A., Visiting Associate Professor (1 September 2011 - 31 August 2012), Department of Medicine (Oncology), Stanford University School of Medicine, Stanford, California, U.S.A.. 2011.
Law M., Ma W.H., Leung R.C.Y., Li S., Wong K.K., Ho W.Y. and Kwong A., Evaluation of patient effective close from sentinel lymph node lymphoscintigraphy in breast cancer: A phantom study with SPECT/CT and ICRP-103 recommendations, European Journal of Radiology. 2012, Epub ahead of print.
Li W.Y., Lam W.W.T., Au A.H.Y., Ye M., Law W.L., Poon J.T.C., Kwong A., Suen D.T.K., Tsang J.Y.S., Girgis A. and Fielding R., Interpreting differences in patterns of supportive care needs between patients with breast cancer and patients with colorectal cancer, Psychooncology. 2012, Epub ahead of print.
Li W.Y., Lam W.W.T., Law W.L., Poon J.T.C., Kwong A., Suen D.T.K. and Fielding R., Interpreting patterns in supportive care needs between breast and colorectal cancers (abstract and poster presentations), Psycho-Oncology Supplement: Abstracts for the 13th World Congress of Psycho-Oncology, 16–20 October 2011, Antalya, Turkey. 2011, 20(Suppl 2): 230-231.
Ng E.K.O., Leung P.H.C., Shin V.Y., Wong L.P., Ma E.S.K., Jin H.C., Chu K.M. and Kwong A., Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients, PLoS One. 2011, 6(7): e22233.
Ramus S.J., Antoniou A.C., Kuchenbaecker K.B., Soucy P., Beesley J., Chen X., McGuffog I., Sinilinkova O.M., Healey S., Barrowdale D., Lee A., Thomassen M., Gerdes A.M., Kruse T.A., Jensen U.B., Skytte A.B., Caligo M.A., Liljegren A., Lindblom A., Olsson H., Kristoffersson U., Stenmark-Askmalm M., Melin B., SWE-BRCA , Domchek S.M., Nathanson K.L., Rebbeck T.R., Jakubowska A., Lubinski J., Jaworska K., Durda K., Zlowocka E., Gronwald J., Huzarski T., Bryski T., Cybulski C., Toloczko-Grabarek A., Osorio A., Benitez J., Duran M., Tejada M.I., Hamann U., Rookus M., van Leeuwen F.E., Aalfs C.M., Meijers-Heijboe H.E., van Asperen C.J., van Roozendaal K.E., Hoogerbrugge N., Margriet Collee J., Kriege M., van der Luijt R.B., HEBON , EMBRACE , Peock S., Frost D., Ellis S.D., Platte R., Fineberg E., Evans D.G., Lalloo F., Jacobs C., Eethes R., Adlard J., Davidson R., Eccles D., Cole T., Cook J., Paterson J., Douglas F., Brewer C., Hodgson S., Morrison P.J., Walker L., Porteous M.E., Kennedy M.J., Pathak H., Godwin A.K., Stoppa-Lyonnet D., Caux-Moncoutier V., de Pauw A., Gauthier-Villars M., Mazoyer S., Leone M., Calender A., Lasset C., Bonadona V., Hardouin A., Berthet P., Bignon Y.J., Uhrhammer N., Faivre L., Loustalot C., GEMO , Buys S., Daly M., Miron A., Beth Terry M., Chung W., John E.M., Southey M., Goldgar D., Singer C.F., Tea Maria M.K., Pfeiler G., Fink-Retter A., Hansen T.V., Ejlertsen B., Johannsson O.T., Offit K., Kirchnoff T., Gaudet M.M., Vijai J., Robson M., Piedmonte M., Phillips K.A., Van Le L., Hoffsman J.S., Toland A.E., Montagna M., Tognazzo S., Imyanitov E., Isaacs C., Janavicius R., Lazaro C., Bianco I., Tornero E., Navarro M., Moysich K.B., Kalan B.Y., Gross J., Olah E., Vanszko T., Teo S.H., Ganz P.A., Beattie M.S., Dorfling C.M., van Rensburg E.J., Diez O., Kwong A., Schmutzler R.K., Wappenschmidt B., Engel C., Meindl A., Ditsch N., Arnold N., Heidemann S., Heidemann S., Niederacher D., Preisler-Adams S., Gadzicki D., Varon-Mateeva R., Deissler H., Gehrig A., Sutter C., Kast K., Fiebig B., Schafer D., Caldes T., de la Hoya M., Nevanlinna H., Aittomaki K., Plante M., Armanda B., Spurdle A.B., kConFab , Neuhausen S.L., Ding Y.C., Wang X., Lindor N., Fredericksen Z., Pankratz V.S., Peterlongo P., Manoukian S., Peissel B., Zaffaroni D., Bonanni B., Bernard L., Dolcetti R., Papil L., Ottini L., Radice P., Greene M.H., Greene M.H., Mai P.L., Andrulis I.L., Glendon G., Ozcelik H., OCGN , Pharoah P.D.P., Gayther S.A., Simard J., Easton D.F., Couch F.J., Chenevix-Trench G. and on behalf of CIMBA , Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers, Human Mutation. 2012, 33(4): 690-702.
Sestak I..., Cuzick J..., Evans G... and Kwong A., Prevention of breast cancer, ABC on Breast Disease, 4th Edition, British Medical Journal. Oxford, Wiley, 2011, 47-50.
Spurdle A.B., Healey S., Devereau A., Hogervorst F.B., Monteiro A.N., Nathanson K.L., Radice P., Stoppa-Lyonnet D., Tavtigian S., Wappenschmidt B., Couch F.J., Goldgar D.E., Goldgar D., Couch F., Fackenthal J.D., Thomassen M., Teo S.H., Hansen T.V., Borg A., Eeles R., Toland A., Rogan P., Hansen T.V., Guidugli L., Brody L.C., Healey S., Brown M., Kwong A., Lei-po C.W., Nevanlinna H., Garber J., Foretova L., Singer C.F., Blok M.J., Spurdle A.B., Osorio A., Kote-Jarai Z., Wappenschmidt B., Baralle D., Vega A., Blanco A., Santamarina M., Fachal L., Nederlof P., Peock S., Pasini B., Tommasi S., Lafferty A., Arisari A., Konstantopoulou I., Pal T., Simard J., Bonetti A., Voresco L., Peissel B., Evans D.G., Foulkes W., Szabo C., van Asperen C., Jonkers J., Walker L., Mitchell G., Gutierrez-Enriquez S., Diez O., Millot G., Fostira F., Selkirk C., Antoniou A., Monteiro A., Carvalho M., Rubinstein W.S., de la Hoya M., Domchek S., Caputo S., Houdayer C., Blanco I., Lazaro C., Whiley P., Becker A., Aretini P., Eccles D., Caides T., Viel A., Izatt L., Hogervorst F., Radice P., Nathanson K., Pedersen I.S., Vreeswijk M., Neuhausen S., Yannoukakos K., Tucker K., Southey M., Leary J., Caligo M.A., Garcia E.G., Devereau A., Brandao R., Lidereau R., Montagna M., Pertesi M., Cornell M., Rouleau E., Sharan S., Rahman N., Lalloo F., Weitzel J., Campbell J., Cummings , Machakova E., Olopade F., Godwin A., Ozcelik H. and Seminara D., ENIGMA - evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes, Human Mutation. 2012, 33(1): 2-7.
Wong H., Leung R., Kwong A., Chiu J., Liang R., Swanton C. and Yau T.C.C., Integrating molecular mechanisms and clinical evidence in the management of Trastuzumab resistant or refractory HER-2+ metastatic breast cancer, Oncologist. 2011, 16(11): 1535-1546.


Researcher : Lai KY

List of Research Outputs

Hui K.C., Lai K.Y., Chan K.W., Luk J.M., Lee N.P.Y., Chung Y., Cheung L.C., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Clinical correlation of nuclear survivin in esophageal squamous cell carcinoma, Med Oncol.. 2012, [Epub ahead of print].


Researcher : Lam BKY

List of Research Outputs

Fung J.Y.Y., Cheung C.K.Y., Chan S.C., Yuen R.M.F., Chok K.S.H., Sharr W.W., Dai W.C., Chan A.C.Y., Cheung T.T., Tsang S.H.Y., Lam B.K.Y., Lai C.L. and Lo C.M., Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation, Gastroenterology. 2011, 141(4): 1212-1219.


Researcher : Lam CT

Project Title:AACR Annual Meeting 2012 in Chicago, IL The potential role of CD44 in liver regeneration
Investigator(s):Lam CT
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:04/2012


Project Title:Identification of essential genes for the development of HBV-associated HCC
Investigator(s):Lam CT, Fan ST
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:06/2012


List of Research Outputs

Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Lam C.T., Yang Z., Ng N.P., Wan T.M.H., Lau J.C.S., Ho D.W.Y., Fan S.T. and Poon R.T.P., The potential role of CD44 in liver regeneration, The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.


Researcher : Lam WK

List of Research Outputs

Lam W.K., Tsang R.K.Y., Leung G.K.K. and Ho W.K., Management of profuse epistaxis in post-irradiated nasopharyngeal carcinoma patients, The 15th Asian Research Symposium on Rhinology, Singapore, 24 - 26 May 2012.


Researcher : Lamb JR

List of Research Outputs

Peng J., Li D., Chan Y.K., Chen Y., Lamb J.R., Tam P.K.H. and El-Nezamy H.S., Effects of water uptake on melamine renal stone formation in mice, Nephrology Dialysis Transplantation. 2012, 27: 2225-2231.


Researcher : Lan CLL

List of Research Outputs

Lan C.L.L., Chan I.H.Y. and Tam P.K.H., Island flap repair of buried penis, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.


Researcher : Lan LCL

List of Research Outputs

Huang J.S., Tao J.F., Chen K., Dai K.L., Tao Q., Chan I.H.Y., Chung H.Y., Lan L.C.L., Tam P.K.H. and Wong K.K.Y., Thoracoscopic repair of oesophageal atresia: experience of 33 patients from two tertiary referral centres, The 45th Annual Meeting of the Pacific Association of Pediatric Surgeons, Shanghai, China, 3 - 7 June 2012.
Leung J.L., Chung H.Y., Lan L.C.L., Wong K.K.Y. and Tam P.K.H., Management of tracheobronchial obstruction in infants using metallic stents: long-term outcome, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3 - 7 June 2012.


Researcher : Lang BHH

List of Research Outputs

Lang B.H.H., A prospective evaluation of quick intraoperative parathyroid hormone assay at the time of skin closure in predicting clinically relevant hypocalcemia after thyroidectomy, World Journal of Surgery. 2012, Epub ahead of print.
Lang B.H.H., Yih P.C. and Lo C.Y., A review of risk factors and timign for postoperative hematoma after thyroidectomy: is outpatient thyroidectomy really safe?, World Journal of Surgery. 2012, Epub ahead of print.
Lang B.H.H., Current innovations and opinions in the surgical management of differentiated thyroid carcinoma, In: Fahey T.J. (ed.), Updates in the Understanding and Management of Thyroid Cancer. Crotia, Intech, 2012, 199-216.
Lang B.H.H., Yip P.C. and Hung G.K., Does using an energized device in open thyroidectomy reduce complications?, Journal of Surgical Research. 2012, Epub ahead of print.
Lang B.H.H., Wong I.Y., Wong K.P. and Lo C.Y., Eucalcemic parathyroid hormone elevation after parathyroidectomy for primary sporadic hyperparathyroidism: risk factors, trend, and outcome, Annals of Surgical Oncology. 2011, Epub ahead of print.
Lang B.H.H., Yih P.C., Shek T.W., Wan K.Y. and Lo C.Y., Factors affecting the adequacy of lymph node yield in prophylactic unilateral central neck dissection for papillary thyroid carcinoma, Journal of Surgical Oncology. 2012, Epub ahead of print.
Lang B.H.H. and Wong K.P., Feasibility on the use of intraoperative vagal nerve stimulation in gasless, transaxillary endoscopic, and robotic-assisted thyroidectomy, Journal of Laparoendoscopic & Advanced Surgical Techniques. 2011, 21(10): 911-917.
Lang B.H.H., Wong K.P., Wan K.Y. and Lo C.Y., Significance of metastatic lymph node ratio on stimulated thyroglobulin levels in papillary thyroid carcinoma after prophylactic unilateral central neck dissection, Annals of Surgical Oncology. 2011, Epub ahead of print.
Lang B.H.H., Tang A.H., Wong K.P., Shek T.W., Wan K.Y. and Lo C.Y., Significance of size of lymph node metastasis on postsurgical stimulated thyroglobulin levels after prophylactic unilateral central neck dissection in papillary thyroid carcinoma, Annals of Surgical Oncology. 2012, Epub ahead of print.
Lang B.H.H., The role of 18F-fluorodeoxyglucose positron emission tomography in the prognostication, diagnosis, and thyroid carcinoma, Journal of Thyroid Research. 2011, 2012: 198313.
Wong H., Wong K.P., Yau T.C.C., Tang V., Leung R., Chiu J. and Lang B.H.H., Is there a role for unstimulated thyroglobulin velocity in predicting recurrence in papillary thyroid carcinoma patients with detectable thyroglobulin after radioiodine ablation?, Annals of Surgical Oncology. 2012, Epub ahead of print.
Wong I.Y.H. and Lang B.H.H., Minamally invasive parathyroidectomy for primary yyperparathyroidism - current views, issues and controversies, In: Fahey T.J. (ed.), Hyperparathyroidism. Crotia, Intech, 2012, 21-34.
Wong K.P. and Lang B.H.H., Graves' ophthalmopathy as an indication increased the risk of hypoparathyroidism after bilateral thyroidectomy, World Journal of Surgery. 2011, 35(10): 2212-2218.
Wong K.P. and Lang B.H.H., The role of prophylactic central neck dissection in differentiated thyroid carcinoma: issues and controversies, Journal of Oncology. 2011, 2011: 127929.


Researcher : Lau CK

List of Research Outputs

Lau C.K., Yang Z. and Fan S.T., Role of stem cells in normal liver and cancer, Anti-Cancer Agents in Medicinal Chemistry. 2011, 11(6): 522-528.


Researcher : Lau CST

Project Title:The role of Krüppel-like factor 4 in neuroblastoma regression
Investigator(s):Lau CST, Ngan ESW
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2011
Completion Date:06/2012


List of Research Outputs

Ngan E.S.W., Garcia-Barcelo M.M., Yip B.H.K., Poon P.C., Lau C.S.T., Kwok K.M., Sat E.W.Y., Sham M.H., Wong K.K.Y., Wainwright B.J., Cherny S.S., Hui C.C., Sham P.C., Lui V.C.H. and Tam P.K.H., Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung’s disease in mice and humans, Journal of Clinical Investigation. 2011, 121(9): 3467-3478.


Researcher : Lau JCS

List of Research Outputs

Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Lam C.T., Yang Z., Ng N.P., Wan T.M.H., Lau J.C.S., Ho D.W.Y., Fan S.T. and Poon R.T.P., The potential role of CD44 in liver regeneration, The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.


Researcher : Law CFBC

List of Research Outputs

Ma Y.Y., Li C., Law C.F.B.C., Lian Q., Man K. and Lo C.M., 2012Young Investigator Travel Award , 18th International Liver Transplantation Society Congress,may 16 - 19, 2012 San Francisco, Californa, USA Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration . Liver Transplantation, 2012, 18.


Researcher : Law SYK

Project Title:Potential Roles of RON and Its Ligand Macrophage Stimulating Protein (MSP) as Prognostic Markers in Esophageal Squamous Cell Carcinoma (ESCC)
Investigator(s):Law SYK, Luk JMC
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2006


Project Title:Identification and characterization of the roles of cancer stem cells (CSCs) in esophageal squamous cell carcinoma (ESCC) and its implications in therapeutic development
Investigator(s):Law SYK, Lee NPY, Luk JMC
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:12/2007


Project Title:Molecular genetics and clinical advances in the study of esophageal and gastric cancers
Investigator(s):Law SYK
Department:Surgery
Source(s) of Funding:Croucher Advanced Study Institute
Start Date:01/2011


Project Title:Identification of differentially expressed proteins in esophageal squamous cell carcinoma (ESCC) cells after development of resistance to cisplatin
Investigator(s):Law SYK, Lee NPY
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:05/2012


List of Research Outputs

Chan S.H.K., Ko J.M.Y., Chan K.W., Chan Y.P., Tao Q., Hyytiainen M., Keski-Oja J., Law S.Y.K., Srivastava G., Tang J., Tsao G.S.W., Chen H., Stanbridge E.J. and Lung M.L., The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome, International Journal of Cancer. 2011, 129(3): 565-573.
Fan B., Dachrut S., Coral H., Yuen S.T., Chu K.M., Law S.Y.K., Zhang L., Ji J., Leung S.Y. and Chen X., Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer, PLoS One. 2012, 7(4): e29824.
Hui K.C., Lai K.Y., Chan K.W., Luk J.M., Lee N.P.Y., Chung Y., Cheung L.C., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Clinical correlation of nuclear survivin in esophageal squamous cell carcinoma, Med Oncol.. 2012, [Epub ahead of print].
Hui K.C., Chan K.W., Luk J.M.C., Lee N.P.Y., Chung M.F.Y., Cheung C.M., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Cytoplasmic Forkhead Box M1 (FoxM1) in esophageal squamous cell carcinoma significantly correlates with pathological disease stage, World Journal of Surgery. 2012, 36(1): 90-97.
Kong K.L., Kwong D.L.W., Chan H.M., Law S.Y.K., Chen L., Li Y., Qin Y.R. and Guan X., MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor, Gut. 2012, 61(1): 33-42.
Law S.Y.K., Art of the anastomosis of the esophagus, SSAT/ISDS Joint Breakfast Symposium: Optimizing Outcomes For Our Patients: Data and Practice: Combining perioperative patient management and expert technical tips, Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012. 2012.
Law S.Y.K., Chair for Keynote on "Current status of esophageal cancer management in China", The Croucher Foundation Advanced Study Institute on "Molecular Genetics and Clinical Advances in the Study of Esophageal Cancer", Departments of Clinical Oncology and Surgery, The University of Hong Kong. 2012.
Law S.Y.K., Chairman, Hong Kong Society of Upper Gastrointestinal Surgeons Foregut Disorder Workshop. 2012.
Law S.Y.K., Chairperson for session on "Gastro-esophageal Reflux Disease", Association of Private Medical Specialists of Hong Kong. The Multi-specialty Medical MegaConference 2.0, Hong Kong, 14-15 April 2012. 2012.
Law S.Y.K., Cheung Kung-Hai Professorship in Gastrointestinal Surgery, Endowed Professorship, The University of Hong Kong. 2012.
Law S.Y.K., Co-director, The Croucher Foundation Advanced Study Institute on "Molecular Genetics and Clinical Advances in the Study of Esophageal Cancer", Departments of Surgery Clinical Oncology, The University of Hong Kong. 2012.
Law S.Y.K., Diseases of the esophagus and stomach: swallowing difficulties, ulcers, acid reflux and cancer, "Explore the World of Medicine" Public Lecture Series 2012, May Lecture: New Understanding of Diseases of the Esophagus and Stomach, and Minimally Invasive Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, 12 May 2012. 2012.
Law S.Y.K., Esophageal cancer in the elderly: Improvement in treatment results. Symposium VII: aging of the Senses (Abstract), The 7th International Symposium on Healthy Aging: "Live Well, Age Well", Research Centre of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, 3 - 4 March 2012. 2012.
Law S.Y.K., Esophagogastrectomy for carcinoma of the esophagus, In: Fischer J.E., Jones D.B., Pomposelli F.B., Upchurch G.R., Klimberg V.S., Schwaitzberg S.D. and Bland K.I. (eds.), Mastery of Surgery, 6th edition. Philadelphia, Lippincott Williams & Wilkins, 2012, 886-903.
Law S.Y.K., Fifty years of esophageal cancer surgery - Progress and innovation experience from The University of Hong Kong (Abstract), Symposium on "Esophagus Surgery", The 66th Annual Meeting of the Japan Esophageal Society, Karuizawa, Japan, 21-22 June 2012. 2012.
Law S.Y.K., Is minimally invasive preferable to open oesophagectomy? Comment on Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial, Lancet. 2012, 379(9829): 1856-1858.
Law S.Y.K., Moderator: ISDS Free Papers, Esophagus 1: Malignant, International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011. 2011.
Law S.Y.K., Moderator: ISDS Main Session, Gastroesophageal Reflux Disease (GERD): From Heartburn to Cancer, International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011. 2011.
Law S.Y.K., Motility disorders of the esophagus, Joint Surgical Symposium, Block I of 3-Year Interactive Program, The University of Hong Kong and Hong Kong Sanatorium & Hospital, Hong Kong, 6 January 2012. 2012.
Law S.Y.K., Multimodal strategies for AEG, Session on "ISDS Main Session, Adenocarcinoma of esophago-gastric junction (AEG)", International Surgical Week ISW 2011, Yokohama, Japan, 28 August - 1 September 2011.
Law S.Y.K., Organizing Committee Member, Annual Scientific Meeting 2011, The College of Surgeons of Hong Kong & Macau Surgical Association, Hong Kong, 17-18 September 2011. 2011.
Law S.Y.K., Recent advances in understanding and treatment of esophageal and gastric cancer, Weekly Health Column in Oriental Daily News by Li Ka Shing Faculty of Medicine. 2012.
Law S.Y.K., Session on "Open vs Lap vs Robotic Surgery: Advantages and Disadvantages (2), Thoracoscopic and laparoscopic esophagectomy (Abstract), The 21st World Congress of the International Association of Surgeons, Gastroenterologists and Oncologists, Tokyo, Japan, 9 - 12 November 2011.
Law S.Y.K., Surgical treatments: Heller's myotomy, robotics, Session on "Motility disorders", Hong Kong Society of Upper Gastrointestinal Surgeons Foregut Disorder Workshop, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 9 - 10 March 2012. 2012.
Law S.Y.K., The art and science of esophageal anastomosis, Scientific Program, Session III, International Meeting - Innovation in Esophageal Surgery, Milano, Italy, 28 November 2011. 2011.
Law S.Y.K., The role of minimal access oesophageal cancer surgery, Annual Scientific Meeting of The European Society of Esophagology, Newcastle, United Kingdom, 24-26 November 2011. 2011.
Law S.Y.K., Transhiatal vs. transthoracic esophagectomy, Session on "ISDS Main Session, Treatment of locally advanced esophageal cancer", International Surgical Week ISW 2011, Yokohama, Japan, 28 August - 1 September 2011.
Law S.Y.K., Video Interview on personal interview and views on upper gastrointestinal surgery, Gastro eNewsletter, a monthly newsletter for gastroenterologists and health professionals, Hong Kong Society for Coloproctology, May 2012. 2012.
Law S.Y.K., 吞嚥困難, AM730: 醫理 (由香港醫學專科學院供稿). 2011.
Law S.Y.K., 微創食管切除術的香港經驗, 『主題:創新醫療,關愛生命』,全國食管癌規範化診治指南研討會(成都站),暨華西2011食管外科論壇,中國抗癌協會食管癌專業委員會、中國醫學科學院腫瘤醫院及四川大學華西醫院,四川成都,中國,2011年10月14至16日, 2011.
Law Y., Tong D.K.H. and Law S.Y.K., Efficacy and safety of self-expanding plastic stent (SEPS) in the management of esophageal disorders (Abstract), Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Lo P.H.Y., Ko J.M.Y., Yu Z., Law S.Y.K., Wang L.D., Li J.L., Srivastava G., Tsao G.S.W., Stanbridge E.J. and Lung M.L., The LIM domain protein, CRIP2, promotes apoptosis in esophageal squamous cell carcinoma, Cancer Letters. 2012, 316(1): 39-45.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., Extra Free Paper Session: What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer? (Abstract), Annual Scientific Meeting 2011, The College of Surgeons of Hong Kong and Macau Surgical Association, Hong Kong, 17 - 18 September 2011.
Tong D.K.H., Law S.Y.K. and Chan S.Y., Operative outcomes of colonic interposition in the treatment of esophageal cancer: a three decades experience (Abstract), Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Tong D.K.H. and Law S.Y.K., Post-oesophagectomy anastomotic-bronchial fistula (Case Report), Hong Kong Medical Journal. 2011, 17(4): 325-327.
Tong D.K.H., Law S.Y.K. and Chan S.Y., Robotic-assisted esophageal epiphrenic diverticulectomy, myotomy and Dor Hemi-Fundoplication (Video Abstract), Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, Session on "ISDS Free Papers, Esophagus 1: Malignant", (Abstract), The International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer?, Surgical Practice. 2011, 15(Suppl 2): B7.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, World Journal of Surgery. 2011, 35(Suppl 1): S172.
Wang K., Kan J., Yuen S.T., Shi S.T., Chu K.M., Law S.Y.K., Chan T.L., Kan Z., Chan A.S.Y., Tsui W.Y., Lee S.P., Ho R.S.L., Chan K.W., Cheng H.W.G., Roberts P.C., Rejto P.A., Gibson N.W., Pocalyko D.J., Mao M., Xu J. and Leung S.Y., Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer, AACR Special Conference on Translation of the Cancer Genome: Scientific, Clinical, and Operational Challenges, San Francisco, CA, U.S.A. October. 2011.
Wang K., Kan J., Yuen S.T., Shi S.T., Chu K.M., Law S.Y.K., Chan T.L., Kan Z., Chan A.S.Y., Tsui W.Y., Lee S.P., Ho R.S.L., Chan K.W., Cheng H.W.G., Roberts P.C., Rejto P.A., Gibson N.W., Pocalyko D.J., Mao M., Xu J. and Leung S.Y., Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer, Nature Genetics. 2011, 43(12): 1219-1223.
Wang K., Kan J., Yuen S.T., Shi S.T., Chu K.M., Law S.Y.K., Chan T.L., Kan Z., Chan A.S.Y., Tsui W.Y., Lee S.P., Ho R.S.L., Chan K.W., Cheng H.W.G., Roberts P.C., Rejto P.A., Gibson N.W., Pocalyko D.J., Mao M., Xu J. and Leung S.Y., Faculty Outstanding Research Output Award "Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer", Nat Genet. 2011, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2012, 43(12): 1219-23.
Wong C.L., Chen H., Ko J.M.Y., Chan K.W., Chan Y.P., Law S.Y.K., Chua D.T.T., Kwong D.L.W., Lung H.L., Srivastava G., Tang J.C.O., Tsao G.S.W., Zabarovsky E.R., Stanbridge E.J. and Lung M.L., Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype, International Journal of Cancer. 2012, 130(1): 83-95.
Yam P.P.C., Tong D.K.H. and Law S.Y.K., Hong Kong dollar in the oesophagus (Pictorial Medicine), Hong Kong Medical Journal. 2012, 18(2): 166.
Yam P.P.C., Tong D.K.H. and Law S.Y.K., The 7th Edition American Joint Cancer Committee Staging System for esophageal cancer - A better staging system compared to the old one? (Abstract) "Free Paper Session", Annual Scientific Meeting 2011, The College of Surgeons of Hong Kong & Macau Surgical Association, Hong Kong, 17 - 18 September 2011.
Yam P.P.C., Tong D.K.H. and Law S.Y.K., The 7th Edition American Joint Cancer Committee Staging System for esophageal cancer - a better staging system compared to the old one?, Surgical Practice. 2011, 15(Suppl 2): B3.
Yuen H.F., McCrudden C.M., Grills C., Zhang S.D., Huang Y.H., Chan K.K., Chan Y.P., Wong M.L.Y., Law S.Y.K., Srivastava G., Fennell D.A., Dickson G., El-Tanani M. and Chan K.W., Combinatorial use of bone morphogenetic protein 6, noggin and SOST significantly predicts cancer progression, Cancer Sci. 2012, 103(6): 1145-54.
Yuen H.F., McCrudden C.M., Chan K.K., Chan Y.P., Wong M.L.Y., Chan Y.K., Khoo U.S., Law S.Y.K., Srivastava G., Lappin T.R., Chan K.W. and EI-Tanani M., The role of pea3 group transcription factors in esophageal squamous cell carcinoma, American Journal of Pathology. 2011, 179(2): 992-1003.


Researcher : Law WL

Project Title:Self-expanding metallic stents for the poor patients with malignant colorectal obstruction
Investigator(s):Law WL, Chu KW
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2004


Project Title:Study of gene expression from rectal swabs to distinguish subjects of colon cancer, risk for colon cancer and healthy controls
Investigator(s):Law WL, Pang RWC
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Chan W.M., Lau L.S., Kwok K.M., Law W.L., Ho J.C.M., Chu K.M. and Poon R.T.P., A randomized, double-blind, placebo-controlled, ascending dose infusion trial of the pharmacokinetics of recombinant human Gelsolin in patients with decreased natural Gelsolin levels, American Thoracic Society International Conference, Denver, U.S.A., 13 - 18 May 2011. American Journal of Respiratory and Critical Care Medicine. 2011, 183: A5601.
Law W.L., Anthony and Anne Cheung Professorship in Innovative and Minimally Invasive Surgery, Endowed Professorship, The University of Hong Kong. 2012.
Law W.L., Challenges in laparoscopic surgery: tips and tricks, Colorectal Scientific Week 2012, Singapore General Hospital, Singapore, 23-26 April 2012. 2012.
Law W.L., Current trend in minimally invasive surgery, "Explore the World of Medicine" Public Lecture Series 2012, May Lecture: New Understanding of Diseases of the Esophagus and Stomach, and Minimally Invasive Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, 12 May 2012. 2012.
Law W.L., Does single incision laparoscopic colorectal surgrey offer other benefits other than cosmesis?, The 17th International Surgical Symposium, Chinese University of Hong Kong, Hong Kong, 4 - 5 November 2011. 2011.
Law W.L., Expectant future of minimal invasive surgery for colorectal cancer - Hong Kong viewpoint, Minimally Invasive Colorectal Forum, National Taiwan University Taipei, Taiwan, 7 August 2011. 2011.
Law W.L., Fast-track surgery: why should we do it?, International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011. 2011.
Law W.L., From laparoscopic to LESS colectomy, Kwong Wah Hospital, Hong Kong, 14-15 June 2012. 2012.
Law W.L., Laparoscopic intersphincteric resection, The 2nd International Laparoscopic TME Symposium, Portsmouth, United Kingdom, 14 - 15 March 2012. 2012.
Law W.L., Laparoscopoic colorectal surgery: the 20 years on (presentation as Honorary Chair), The 20th Anniversary Meeting, Society of Laparoendoscopic Surgeons and Endo Expo 2011, Los Angeles, California, U.S.A., 14 - 17 September 2011. 2011.
Law W.L., Minimally invasive surgery for colorectal cancer: Hong Kong experience, 第十五屆全國普通外科學術會議大會, Changsha, China, 14-17 October 2011, 2011.
Law W.L., Operating room of the future, The Art of Surgery Today, The last Supper organised by the 1st Department of Surgery, Papageorgiou Hospital, Thessaoniki, Greece, 4-5 May 2012. 2012.
Law W.L., Options in the patient with obstructing colon mass, International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011. 2011.
Law W.L., Pitfalls in laparoscopic colectomy, Colorectal Scientific Week 2012, Singapore General Hospital, Singapore, 23-26 April 2012. 2012.
Law W.L., Recent advances in MIS, The 10th Yonsei International Colorectal Symposium and the 1st Asian Pacific Colorectal Congress, Seoul, Korea, 18 - 19 May 2012. 2012.
Law W.L., Reconstruction of neorectum after low anterior resection: what is the evidence?, Annual Scientific Meeting 2011, College of Surgeons Hong Kong, Hong Kong, 18 September 2011. 2011.
Law W.L., Reviewer, Endoscopy. 2011.
Law W.L., Robotic assisted rectal surgery: is it better than conventional laparoscopy?, The Art of Surgery Today, The last Supper organised by the 1st Department of Surgery, Papageorgiou Hospital, Thessaoniki, Greece, 4-5 May 2012. 2012.
Law W.L., Robotic rectal surgery, 第十二屆廣東省大腸癌學術會議, Guangzhou, China, 19-20 August 2011, 2011.
Law W.L., Robotic rectal surgery, Asian American MultiSpecialty Summit V, Honolulu, Hawaii, U.S.A., 1 - 4 February 2012. 2012.
Law W.L., SILS in colectomy, The 7th Meeting of Internaional Society of Laparoscopic Colorectal Surgeons, Chemford, United Kingdom, 5 - 7 September 2011. 2011.
Law W.L., Single incision colectomy: is there any advantage other than cosmesis, The Art of Surgery Today, The last Supper organised by the 1st Department of Surgery, Papageorgiou Hospital, Thessaoniki, Greece, 4-5 May 2012. 2012.
Law W.L., Single incision laparoscopic colectomy: what is the evidence, Colorectal Scientific Week 2012, Singapore General Hospital, Singapore, 23-26 April 2012. 2012.
Law W.L., Single incision laparoscopic left colectomy/high anterior resection, Single Incision Laparoscopic and Transanal Colorectal Surgery Course, Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting, San Diego, California, U.S.A., 7 - 10 March 2012. 2012.
Law W.L., Single incision laparoscopic surgery for TME, The 2nd International Laparoscopic TME Symposium, Portsmouth, United Kingdom, 14 - 15 March 2012. 2012.
Law W.L., Stapled hemorrhoidopexy, Seoul International Symposium for Coloproctology 2012, Seoul, Korea, 7-8 April 2012. 2012.
Law W.L., Poon T.C.J., Fan J.K.M. and Lo O.S.H., Survival following laparoscopic versus open resection for colorectal cancer, International Journal of Colorectal Disease. 2012, Epub ahead of print.
Law W.L., Updates on robotic colorectal surgery, The 20th Anniversary Meeting, Society of Laparoendoscopic Surgeons and Endo Expo 2011, Los Angeles, California, U.S.A., 14 - 17 September 2011. 2011.
Law W.L., 腹腔鏡輔助結直腸癌手術進展: 香港大學的經驗, 第三屆結直腸癌腹腔鏡與TME進展高級學習班, Guangzhou Cancer Hospital, Guangzhou, China, 17 December 2011, 2011.
Li W.Y., Lam W.W.T., Au A.H.Y., Ye M., Law W.L., Poon J.T.C., Kwong A., Suen D.T.K., Tsang J.Y.S., Girgis A. and Fielding R., Interpreting differences in patterns of supportive care needs between patients with breast cancer and patients with colorectal cancer, Psychooncology. 2012, Epub ahead of print.
Poon J.T.C., Law W.L., Chow L.C., Fan J.K.M. and Lo O.S.H., Outcome of laparoscopic resection for colorectal cancer in patients with high operative risk, Annals of Surgical Oncology. 2011, 18(7): 1884-1890.
Poon T.C.J., Cheung C.W., Law W.L., Fan J.K.M. and Lo O.S.H., A randomized controlled trial comparing the outcomes of patients who undergo single port laparoscopic colectomy and conventional laparoscopic colectomy, SAGES 2012, San Diego, California. 7-10 March . 2012.
Poon T.C.J., Cheung C.W., Fan J.K.M., Lo O.S.H. and Law W.L., Single incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized controlled trial, The Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting 2012, San Diego, California, U.S.A., 7 - 10 March 2012.
Poon T.C.J., Cheung C.W., Fan J.K.M., Lo O.S.H. and Law W.L., Single-incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized, controlled trial, Surgical endoscopy. 2012, Epub ahead of print.
Quereshy F.A., Poon T.C.J. and Law W.L., Long-term outcomes of stenting as a bridge to surgery for acute left-sided malignant colonic obstruction, American Society of Clinical Oncology Annual Meeting 2012, Chicage, Illinois, U.S.A., 1 - 5 June 2012.
Salazar R., Marshall J., Capdevila J., Glimelius B., de Waard J.W., Van Der Hoeven J., Klaase J., Bibeau F., Bachleitner-Hofmann , Midgley R.A., Levine E.A., Law W.L., Asano M., Chang G.J., Cohen S.M., Beart R.W., Goldfarb P.M., McCarter M., Stork L. and Rosenberg R., The PARSC trial, a prospective study for the assessment of recurrence risk in stage II colon cancer patients using ColoPrint, American Society of Clinical Oncology Annual Meeting 2012, Chicage, Illinois, U.S.A., 1 - 5 June 2012.
She W.H., Poon T.C.J., Fan J.K.M., Lo O.S.H. and Law W.L., Stoma reversal in patients who underwent low anterior resection and diversion stoma for rectal cancer, Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Wong C.K.H., Lam C.L.K., Poon T.C.J., McGhee S., Law W.L., Kwong D.L.W., Tsang J.W.H. and Chan P., Direct medical costs of care for Chinese patients with colorectal neoplasia: a health care service provider perspective, Journal of Evaluation in Clinical Practice. Blackwell Publishing, 2011, 18: 1186-1195.
Wong C.K.H., Lam C.L.K., Rowen D., McGhee S., Ma K.P., Law W.L., Poon T.C.J., Chan P., Kwong D.L.W. and Tsang J.W.H., Mapping the functional assessment of cancer therapy-general or -colorectal to SF-6D in Chinese patients with colorectal neoplasm, Value in Health. Elsevier, 2012, 15(3): 495-503.
Wong C.K.H., Lam C.L.K., McGhee S., Law W.L., Poon T.C.J., Chan P., Kwong D.L.W., Tsang J.W.H., Rowen D.L. and Brazier J., Mapping the functional assessment of cancer therapy-general or -colorectal to preference-based values measured by SF-6D in patients with colorectal neoplasm, 18th Annual Conference of the International Society for Quality of Life Research, Denver, Colorado, USA, 28 October 2011.
Wong K.H., Lam C.L.K., Law W.L., Poon J.T.C., Chan P., Kwong D.L.W. and Tsang J.W.H., Validity and reliability study on traditional Chinese FACT-C in Chinese patients with colorectal neoplasm., Journal of Evaluation in Clinical Practice. 2011.
Wong K.P., Poon T.C.J., Fan J.K.M. and Law W.L., Prognostic value of lymph node ratio in stage III colorectal disease, Colorectal Disease. 2011, 13(10): 1116-1122.


Researcher : Lee D

List of Research Outputs

Leung G.K.K., Sun S., Lee D., Lee N.P. and Pu J.K.S., Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide, The 9th Meeting of the Asian Society of Neuro-oncology, Taipei, Taiwan, 20 - 22 April 2012.
Zhang X., Sun S., Pu J.K.S., Tsang C.O.A., Lee D., Lui W.M., Wong S.T.S., Leung G.K.K. and Man V.O.Y., Long non-coding RNA expression profiles predict clinical phenotypes in glioma, Neurobiology of Disease. 2012, 48(1): 1-8.


Researcher : Lee NPY

Project Title:Tight-junction claudin-19 in kidney development and renal disease
Investigator(s):Lee NPY, Luk JMC, Tam PC
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:microRNA-125b as a tumor suppressor of liver cancer by targeting eIF5A2
Investigator(s):Lee NPY
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2011


Project Title:The International Liver Congress 2012-47th Annual Meeting of the European Association for the Study of the Liver Monoclonal antibody against cadherin-17 as a potential treatment for liver cancer
Investigator(s):Lee NPY
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2012
Completion Date:04/2012


Project Title:An Investigation into the Pre-clinical Efficacy of Monoclonal Antibody against Cadherin-17 and its Combined Treatment with Chemotherapeutic Drugs using Live Imaging in an Orthotopic Tumor Xenograft Model (ITS/280/11)
Investigator(s):Lee NPY, Sun S, Fan ST
Department:Surgery
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:06/2012


Project Title:An Investigation into the Pre-clinical Efficacy of Monoclonal Antibody against Cadherin-17 and its Combined Treatment with Chemotherapeutic Drugs using Live Imaging in an Orthotopic Tumor Xenograft Model
Investigator(s):Lee NPY, Sun S, Fan ST
Department:Surgery
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:06/2012


Project Title:An Investigation into the Pre-clinical Efficacy of Monoclonal Antibody against Cadherin-17 and its Combined Treatment with Chemotherapeutic Drugs using Live Imaging in an Orthotopic Tumor Xenograft Model (ITS/280/11)
Investigator(s):Lee NPY, Sun S, Fan ST
Department:Surgery
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:06/2012


Project Title:Elucidating the role of cadherin-17 on proliferation and apoptosis of liver cancer cells
Investigator(s):Lee NPY
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:06/2012


List of Research Outputs

Fatima S., Lee N.P.Y., Tsang F.H., Kolligs F.T., Ng I.O.L., Poon R.T.P., Fan S.T. and Luk J.M.C., Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway by influencing β-catenin in hepatocellular carcinoma, Oncogene. 2012, Epub on 2012-01-16.
Fatima S., Lee N.P.Y. and Luk J.M.C., Dickkopfs and Wnt/β-catenin signalling in liver cancer, World Journal of Clinical Oncology. 2011, 2(8): 311-325.
Hao K., Lamb J., Zhang C., Xie T., Wang K., Zhang B., Chudin E., Lee N.P.Y., Mao M., Zhong H., Greenawalt D., Ferguson M.D., Ng I.O.L., Sham P.C., Poon R.T.P., Molony C., Schadt E.E., Dai H. and Luk J.M.C., Clinicopathologic and gene expression parameters predict liver cancer prognosis, BMC Cancer. 2011, 11(1): 481.
Hui K.C., Lai K.Y., Chan K.W., Luk J.M., Lee N.P.Y., Chung Y., Cheung L.C., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Clinical correlation of nuclear survivin in esophageal squamous cell carcinoma, Med Oncol.. 2012, [Epub ahead of print].
Hui K.C., Chan K.W., Luk J.M.C., Lee N.P.Y., Chung M.F.Y., Cheung C.M., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Cytoplasmic Forkhead Box M1 (FoxM1) in esophageal squamous cell carcinoma significantly correlates with pathological disease stage, World Journal of Surgery. 2012, 36(1): 90-97.
Ivanovska I., Zhang C., Liu A.M.L., Wong K.F., Lee N.P.Y., Lewis P., Philippar U., Bansal D., Buser C., Scott M., Mao M., Poon R.T.P., Fan S.T., Cleary M.A., Luk J.M.C. and Dai H., Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma, PLoS One. 2011, 6(9): e24582.
Lamb J.R., Zhang C., Xie T., Wang K., Zhang B., Hao K., Chudin E., Fraser H.B., Millstein J., Ferguson M., Suver C., Ivanovska I., Scott M., Poon R.T.P., Fan S.T., Yeung C., Lee N.P.Y. and Luk J.M.C., Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting, PLoS One. 2011, 6(7): e20090.
Lee N.P.Y., Wang Y. and Luk J.M.C., Monoclonal antibody against cadherin-17 as a potential treatment for liver cancer (Poster & Abstract), The 47th Annual Meeting of the European Association for the Study of the Liver and the International Liver Congress 2012, Barcelona, Spain, 18-22 April 2012.
Lee N.P.Y., The blood-biliary barrier, tight junctions and human liver diseases (Chapter 8), Biology and Regulation of Blood-Tissue Barriers. Editor: Cheng CY. not known, Landes Biosciences, 2012, not applicable: not known.
Liu A.M.L., Yao T., Wang W., Wong K.F., Lee N.P.Y., Fan S.T., Poon R.T.P., Gao C. and Luk J.M.C., Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study, BMJ Open. 2012, 2(2): e000825.
Lu W.J., Lee N.P.Y., Wadhwa R. and Luk J.M.C., Mortalin-p53 interaction as a target for liver cancer therapy (Chapter 17), Mortalin Biology: Life, Stress and Death. Editors: Kaul SC and Wadhwa R. not known, Springer, 2012, not applicable: not known.
Luk J.M.C., Burchard J., Zhang C., Liu A.M.L., Wong K.F., Shek H.P., Lee N.P.Y., Fan S.T., Poon R.T.P., Ivanovska I., Philippar U., Cleary M.A., Buser C.A., Shaw P.M., Lee C.N., Tenen D.G., Dai H. and Mao M., DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival, Journal of Biological Chemistry. 2011, 286(35): 30706-30713.
Shek H.P., Luk J.M.C. and Lee N.P.Y., Targeting serine peptidase inhibitor, Kazal type 1 (SPINK1) as a potential treatment for hepatocellular carcinoma (Poster and Abstract), The 5th Annual Conference of the International Liver Cancer Association, Hong Kong, 2-4 September 2011.
Shek H.P. and Lee N.P.Y., Tumorigenic properties of serine peptidase inhibitor, Kazal type 1 (SPINK1) in hepatocellular carcinoma (Poster & Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Sun S., Wong S.T.S., Zhang X., Pu J.K.S., Lee N.P.Y., Day P.J., Ng K.B., Lui W.M. and Leung G.K.K., Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines , Journal of Neuro-oncology. 2012, 107(1): 89-100.
Sung W.K., Zheng H., Li S., Chen R., Liu X., Li Y., Lee N.P.Y., Lee W.H., Wong K.F., Liu A.M.L., Poon R.T.P., Fan S.T., Chan K.L. and Luk J.M.C., Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma, Nature Genetics. 2012, 44(7): 765-769.


Researcher : Lee PY

Project Title:Tight-junction claudin-19 in kidney development and renal disease
Investigator(s):Lee NPY, Luk JMC, Tam PC
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:microRNA-125b as a tumor suppressor of liver cancer by targeting eIF5A2
Investigator(s):Lee NPY
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2011


Project Title:The International Liver Congress 2012-47th Annual Meeting of the European Association for the Study of the Liver Monoclonal antibody against cadherin-17 as a potential treatment for liver cancer
Investigator(s):Lee NPY
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2012
Completion Date:04/2012


Project Title:An Investigation into the Pre-clinical Efficacy of Monoclonal Antibody against Cadherin-17 and its Combined Treatment with Chemotherapeutic Drugs using Live Imaging in an Orthotopic Tumor Xenograft Model (ITS/280/11)
Investigator(s):Lee NPY, Sun S, Fan ST
Department:Surgery
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:06/2012


Project Title:An Investigation into the Pre-clinical Efficacy of Monoclonal Antibody against Cadherin-17 and its Combined Treatment with Chemotherapeutic Drugs using Live Imaging in an Orthotopic Tumor Xenograft Model
Investigator(s):Lee NPY, Sun S, Fan ST
Department:Surgery
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:06/2012


Project Title:An Investigation into the Pre-clinical Efficacy of Monoclonal Antibody against Cadherin-17 and its Combined Treatment with Chemotherapeutic Drugs using Live Imaging in an Orthotopic Tumor Xenograft Model (ITS/280/11)
Investigator(s):Lee NPY, Sun S, Fan ST
Department:Surgery
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:06/2012


Project Title:Elucidating the role of cadherin-17 on proliferation and apoptosis of liver cancer cells
Investigator(s):Lee NPY
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:06/2012


List of Research Outputs

Lee P.Y., Zhang R., Li V., Liu X., Sun R.W.Y., Che C.M. and Wong K.K.Y., Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation, International Journal of Nanomedicine. 2012, 7: 731-737.


Researcher : Lee PY

List of Research Outputs

Lee P.Y., Zhang R., Li V., Liu X., Sun R.W.Y., Che C.M. and Wong K.K.Y., Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation, International Journal of Nanomedicine. 2012, 7: 731-737.


Researcher : Leon YY

Project Title:9th Joint Meeting of ICS-ISICR Avian influenza viruses (H9N2/G1) activation of p38-MAPK and induction of tumor necrosis factor-α (TNF-α) expression are negatively regulated by protein phosphatase 2A (PP2A)
Investigator(s):Leon YY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2011
Completion Date:10/2011


List of Research Outputs

Cherny S.S., Garcia-Barcelo M.M., Leon Y.Y., So M.T., Sham P.C. and Tam P.K.H., RET mutational spectrum in Hirschsprungs disease: Evaluation of 601 Chinese patients, 12th International Congress of Human Genetics. 2011, 790.
Leon Y.Y., So M.T., Lui V.C.H., Hofstra R.M.W., Tam P.K.H., Ngan E.S.W. and Garcia-Barcelo M.M., Functional analyses of RET mutations in Chinese Hirschsprung disease patients, Birth Defects Research (Part A): Clinical and Molecular Teratology. 2012, 94(1): 47-51.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.


Researcher : Leon YY

List of Research Outputs

Cherny S.S., Garcia-Barcelo M.M., Leon Y.Y., So M.T., Sham P.C. and Tam P.K.H., RET mutational spectrum in Hirschsprungs disease: Evaluation of 601 Chinese patients, 12th International Congress of Human Genetics. 2011, 790.
Leon Y.Y., So M.T., Lui V.C.H., Hofstra R.M.W., Tam P.K.H., Ngan E.S.W. and Garcia-Barcelo M.M., Functional analyses of RET mutations in Chinese Hirschsprung disease patients, Birth Defects Research (Part A): Clinical and Molecular Teratology. 2012, 94(1): 47-51.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.


Researcher : Leung GKK

Project Title:Self-assembling peptide nanofiber scaffold (SAPNS) as a potential neuro-regenerative biomaterial in surgically induced brain injury.
Investigator(s):Leung GKK, Wu W
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:02/2011


Project Title:16th Annual Scientific Meeting & Education Day of the Society for Neuro-Oncology Acquired temozolomide resistance in human malignant gliomas: a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide.
Investigator(s):Leung GKK
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2011
Completion Date:11/2011


List of Research Outputs

Chong B.H., Lau K.K., Chan K.H., Lui W.M., Leung G.K.K., Lau C.P., Tse H.F., Pu J.K.S. and Siu C.W., Use of aspirin in Chinese after recovery from primary intracranial haemorrhage, Thrombosis and Haemostasis. 2012, 107(2): 241-247.
Chu J.P., Mak H.K.F., Yau K.K.W., Zhang L., Tsang J.W.H., Chan Q. and Leung G.K.K., Chu JP, Mak HK*, Yau KK, Zhang L, Tsang J, Chan Q, Leung KK. A pilot study on correlation of MR perfusion (Ktrans) and diffusion (apparent diffusion coefficient) parameters in brain tumors at 3Tesla. Cancer Imaging , 2012, 12: 1-6.
Guo J., Leung G.K.K. and Wu W., Bridging the gap for regeneration after CNS injury by nanofiber scaffolds: use of SPANS for traumatic brain and spinal cord injury, In: Martin C.R., Preedy V.R. and Hunter R.J. (eds.), Nanomedicine and the Nervous System. Boca Raton, Science Publishers, 2012, 330-346.
Lam C.L.K., Chan G.C.F., Lam T.H., Lee P.P.W., Leung A.Y.M., Leung G.K.K., Tang S.C.W. and Tsao G.S.W., 育醫造才: 探索醫學世界 第二冊, 香港大學李嘉城醫學院, 2012, 第二冊.
Lam W.K., Tsang R.K.Y., Leung G.K.K. and Ho W.K., Management of profuse epistaxis in post-irradiated nasopharyngeal carcinoma patients, The 15th Asian Research Symposium on Rhinology, Singapore, 24 - 26 May 2012.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in human malignant gliomas: a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide, The Society for NeuroOncology. 2011.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in malignant gliomas - a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide (P4HB) (Abstract), Neuro-oncology. 2011, 13(3): 111.
Leung G.K.K., Wang Y., Un T. and Wu W., An animal study comparing electrocautery and nanopeptide scaffold in neurosurgical haemostasis, The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Leung G.K.K., Lui W.M., Yuen M.M.A., Chow W.S. and Tse P.Y.H., An endoscopic modification of the simultaneous 'above and below' approach to large pituitary adenomas, Pituitary 2012. 2012, 15(2): 237-241.
Leung G.K.K., Clinical teaching and problem based learning, Clinical Teaching Reform Training Workshop, The Medical School of the Peking University, Beijing, China. 2012.
Leung G.K.K., Clinical trial of umbilical cord blood for spinal cord injury: protocol and surgery, International Association of Neurorestoratology V and the 9th Global College Neuroprotection and Neuroregeneration Conference, Xian, China, 4 - 7 May 2012. 2012.
Leung G.K.K., Combating temozolomide resistance in malignant glioma using a proteomics approach, Brain 2012, the 9th Asia Pacific Multidisciplinary Meeting for Nervous System Diseases, the Chinese University of Hong Kong, Hong Kong, 13 - 14 January 2012. 2012.
Leung G.K.K., Pang K.K.W., Tsang K.L., Tse C.T.A., Pang S.Y.Y., Cheung R.T.F., Ho S.L., Lau G.K.K., Teo K.C. and Chan K.H., Cryptococcal meningitis: a hospital-based study, Seventeenth Medical Research Conference. 2012, 47.
Leung G.K.K., Educational Booklet on Brain Tumour, The Hong Kong Anti-Cancer Society. 2011.
Leung G.K.K., Endoscopic pituitary surgery, Hong Kong Surgical Forum - Summer, The University of Hong Kong, Hong Kong, 16 July 2011. 2011.
Leung G.K.K. and Tsang C.O.A., External ventricular drian infections - can an extended subcutaneous tunnel reduce infection rate?, In: Pant S. and Cherian I. (eds.), Hydrocephalus. Croatia, InTech, 2012, 87-98.
Leung G.K.K., How many trauma centres does Hong Kong need?, Queen Elizabeth Hospital Trauma Symposium, Hong Kong, September 2011. 2011.
Leung G.K.K., Sun S., Lee D., Lee N.P. and Pu J.K.S., Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide, The 9th Meeting of the Asian Society of Neuro-oncology, Taipei, Taiwan, 20 - 22 April 2012.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Identifying molecular candidates associated with acquired temozolomide resistance in human malignant glioma - a proteomics approach., The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Leung G.K.K., Neurovascular trauma, Hong Kong Surgical Forum - Winter, The University of Hong Kong, Hong Kong, 14 January 2012. 2012.
Leung G.K.K. and Yuen W.K., Operative intervention for traumatic brain injuries in the elderly, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Leung G.K.K., Yuen W.K., Wong H.T. and Li L.F., Operative intervention for traumatic brain injury in the elderly, The 36th Annual Scientific Meeting of the Royal College of Surgeons of Thailand, Pattaya, Thailand, 14 - 17 July 2011.
Leung G.K.K., Outcome-based training in surgery, International College of Surgeons Medical Education Conference. 2011.
Leung G.K.K., Patient safety in clinical education, The International Medical School of Jinan University, Guangzhou, China. 2012.
Leung G.K.K., Wang Y. and Wu W., Peptide nanofiber scaffold for brain tissue reconstruction, In: Duzgunes N. (ed.), Methods in Enzymology. Volume 508. Nanomedicine: Cancer, Diabetes, and Cardiovascular, Central Nervous System, Pulmonary and Inflammatory Diseases. San Diego, Academic Press, 2012, 177-190.
Leung G.K.K., Ho J.C.Y. and Pu J.K.S., Pituitary enlargement in spontaneous intracranial hypotension - a diagnostic pitfall, Acta Neurochirurgica(Wien). 2011, 153(12): 2445-2446.
Leung G.K.K. and Lui W.M., Pure endonasal endoscopic transsphenoidal surgery - an endocrinologist-led assessment of a single-surgeon's experience, 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Leung G.K.K., Recurrent malignant glioma, Current Trend in the Management of Malignant Glioma, Taiwan, September 2011. 2011.
Leung G.K.K., Self-assembling peptide nanofiber scaffold as a potential carrier of transplantable cells for neuro-regenerative therapy, Postgraduate Symposium 2012, Department of Anatomy, The University of Hong Kong, June 2012.
Leung G.K.K., Student attitudes towards patient safety, In: Zysberg L. (ed.), Student Attitudes. New York, Nova Sciences, 2011, 269-278.
Leung M., So F.L., Cheng A., Yeung J.H.H., Wong H.H.T. and Leung G.K.K., Characterization of sports-related injury attendance at trauma centres in Hong Kong, Hospital Authority Convention 2012.
Leung M., So F.L., Cheng A., Yeung J.H.H., Wong H.H.T. and Leung G.K.K., Pediatric trauma: causes and pattern in Hong Kong. , Hospital Authority Convention 2012. . 2012.
Mei L., Ding X., Tsang S.Y., Pun F.W., Ng S.K., Yang J., Zhao C., Li D., Wan W., Yu C.H., Tan T.C., Poon W.S., Leung G.K.K., Ng H.K., Zhang L. and Xue H., AluScan: a method for grnome-wide scanning of sequence and structure variations in the human genome, BMC Genomics 2011. 2011, 12: 564-572.
Pong V., Chan K.H., Chong B.H., Lui W.M., Leung G.K.K., Tse H.F., Pu J.K.S. and Siu D.C.W., Long-term outcome and prognostic factors after spontaneous cerebellar hemorrhage. , Cerebellum. 2012.
Pu J.K.S., Chan R.T.T., Ng G.K.B., Leung G.K.K., Hung K.N. and Fung C.F., Using bevacizumab in the fight against malignant glioma: first results in Asian patients, Hong Kong Medical Journal. 2011, 17(4): 274-279.
Sun S., Pu J.K.S., Leung G.K.K. and Wong S.T.S., Prolyl 4-hydroxylase, Beta polypeptide (P4HB) as a Potential Target for Combating Temozolomide Resistance in Human Malignant Glioma, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Sun S. and Leung G.K.K., Prolyl 4-hydroxylase, beta polypeptide (P4HB): a potential target for overcoming temozolomide resistance in human malignant glioma, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.
Sun S., Wong S.T.S., Zhang X., Pu J.K.S., Lee N.P.Y., Day P.J., Ng K.B., Lui W.M. and Leung G.K.K., Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines , Journal of Neuro-oncology. 2012, 107(1): 89-100.
Sun S. and Leung G.K.K., Proteomic alterations associated with acquired temozolomide resistance in human malignant gliomas: the role of prolyl 4-hydroxylase, beta polypeptide, Round Asia Oncology Forum 2011, Shanghai, China, 27 - 28 August 2011.
Taw B.B.T., Lam A.C.S., Hung K.N., Lui W.M., Leung G.K.K. and Ho F.L.Y., Functional survival after acute care for severe head injury at a designated trauma center in Hong Kong, Asian Journal of Surgery. 2012, Epub 06-06-2012.
Tsang C.O., Leung K.M., Leung G.K.K. and Lui W.M., Carotid blowout syndrome: EC-IC bypass and endovascular management of ruptured radiation-related pseudoaneurym in nasopharyngeal cancer patients, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Tsang C.O.A., Leung G.K.K. and Lui W.M., Best Oral Free Paper in General Neurosurgery (non-HST), The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011. 2011.
Wong W.H., Wong H.T., Tong D.K.H., Leung G.K.K. and Yuen W.K., Utilization of whole body computed tomography (WB-CT) for trauma patients, The Advanced Trauma Life Support Region XVI Meeting, Malaysia. 2012.
Xia H., Cheung W.K.C., Ng S.S., Jiang X., Jiang S., Sze J., Leung G.K.K., Chan D.T.M., Bian X., Kung H., Poon W.S. and Lin M.C., Loss of brain-enriched miR-124 microRNA enhances stem-like traits and invasiveness of glioma cells, Journal of Biological Chemistry. 2012, 287(13): 9962-9971.
Zhang X., Sun S., Pu J.K.S., Tsang C.O.A., Lee D., Lui W.M., Wong S.T.S., Leung G.K.K. and Man V.O.Y., Long non-coding RNA expression profiles predict clinical phenotypes in glioma, Neurobiology of Disease. 2012, 48(1): 1-8.


Researcher : Leung KM

List of Research Outputs

Tsang C.O., Leung K.M., Leung G.K.K. and Lui W.M., Carotid blowout syndrome: EC-IC bypass and endovascular management of ruptured radiation-related pseudoaneurym in nasopharyngeal cancer patients, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.


Researcher : Leung MC

List of Research Outputs

Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.


Researcher : Leung PHC

List of Research Outputs

Ng E.K.O., Leung P.H.C., Shin V.Y., Wong L.P., Ma E.S.K., Jin H.C., Chu K.M. and Kwong A., Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients, PLoS One. 2011, 6(7): e22233.


Researcher : Li C

List of Research Outputs

Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Ma Y.Y., Li C., Law C.F.B.C., Lian Q., Man K. and Lo C.M., 2012Young Investigator Travel Award , 18th International Liver Transplantation Society Congress,may 16 - 19, 2012 San Francisco, Californa, USA Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration . Liver Transplantation, 2012, 18.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Man K., Wong N., Li C., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, Young Investigator Award, the 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012. 2012.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Li C

List of Research Outputs

Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Ma Y.Y., Li C., Law C.F.B.C., Lian Q., Man K. and Lo C.M., 2012Young Investigator Travel Award , 18th International Liver Transplantation Society Congress,may 16 - 19, 2012 San Francisco, Californa, USA Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration . Liver Transplantation, 2012, 18.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Man K., Wong N., Li C., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, Young Investigator Award, the 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012. 2012.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Li D

List of Research Outputs

Li D., Role of adiponectin in preventing chronic rejection and the underlying molecular immunoregulatory signaling pathway, Thesis, Doctor of Philosophy, The University of Hong Kong. 2012.
Peng J., Li D., Chan Y.K., Chen Y., Lamb J.R., Tam P.K.H. and El-Nezamy H.S., Effects of water uptake on melamine renal stone formation in mice, Nephrology Dialysis Transplantation. 2012, 27: 2225-2231.


Researcher : Li GKH

List of Research Outputs

Chan Y.W., Li G.K.H., Chung H.P. and Chow V.L.Y., Extramammary Paget's disease: 20 years of experience in Chinese population, International Journal of Surgical Oncology. 2012, Epub ahead of print.


Researcher : Li X

Project Title:The impact of pressure overload on apoptosis in cardiomyocytes
Investigator(s):Li X, Cheung YF
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010


List of Research Outputs

Li X., Cardiothoracic surgery, Post-registration Certificate Course in Perioperative Nursing Course, Hospital Authority, Hong Kong. 2011.
Li X., Congenital heart disease, Invasive and Interventional Cardiology Program for Nurses, Hospital Authority, Hong Kong. 2012.
Zhang Y., Wu W., Sun H., Deng X.L., Cheng L.C., Li X., Tse H.F., Lau C.P. and Li G.R., Modulation of human cardiac transient outward potassium current by EGFR tyrosine kinase and Src-family kinases, Cardiovasc Res.. 2012, 93(3): 424-33.


Researcher : Li Z

List of Research Outputs

Wong S.T.S., Gao W., Li Z., Chan Y.W. and Ho W.K., Epigenetic dysregulation in laryngeal squamous cell carcinoma, Journal of Oncology. 2012, 2012: 739461.


Researcher : Lin C

Project Title:The effect of SARS-associated coronavirus Spike protein on immune regulation of SARS
Investigator(s):Lin C, Chan VSF
Department:Surgery
Source(s) of Funding:VCO SARS Research Fund
Start Date:07/2003


Project Title:Development of DNA and viral vector vaccines against Epstein-Barr virus-positive nasopharyngeal carcinoma
Investigator(s):Lin C
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2003




Researcher : Lin CL

Project Title:The effect of SARS-associated coronavirus Spike protein on immune regulation of SARS
Investigator(s):Lin C, Chan VSF
Department:Surgery
Source(s) of Funding:VCO SARS Research Fund
Start Date:07/2003


Project Title:Development of DNA and viral vector vaccines against Epstein-Barr virus-positive nasopharyngeal carcinoma
Investigator(s):Lin C
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2003




Researcher : Ling C

List of Research Outputs

Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Ling C., The role of graft injury in mobilization of endothelial progenitor cells, myeloid derived suppressor cells and regulatory T cells after liver transplantation, Thesis, Doctor of Philosophy, The University of Hong Kong. 2012.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.


Researcher : Ling C

List of Research Outputs

Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Ling C., The role of graft injury in mobilization of endothelial progenitor cells, myeloid derived suppressor cells and regulatory T cells after liver transplantation, Thesis, Doctor of Philosophy, The University of Hong Kong. 2012.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.


Researcher : Liu AML

List of Research Outputs

Ivanovska I., Zhang C., Liu A.M.L., Wong K.F., Lee N.P.Y., Lewis P., Philippar U., Bansal D., Buser C., Scott M., Mao M., Poon R.T.P., Fan S.T., Cleary M.A., Luk J.M.C. and Dai H., Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma, PLoS One. 2011, 6(9): e24582.
Liu A.M.L., Yao T., Wang W., Wong K.F., Lee N.P.Y., Fan S.T., Poon R.T.P., Gao C. and Luk J.M.C., Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study, BMJ Open. 2012, 2(2): e000825.
Luk J.M.C., Burchard J., Zhang C., Liu A.M.L., Wong K.F., Shek H.P., Lee N.P.Y., Fan S.T., Poon R.T.P., Ivanovska I., Philippar U., Cleary M.A., Buser C.A., Shaw P.M., Lee C.N., Tenen D.G., Dai H. and Mao M., DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival, Journal of Biological Chemistry. 2011, 286(35): 30706-30713.
Sung W.K., Zheng H., Li S., Chen R., Liu X., Li Y., Lee N.P.Y., Lee W.H., Wong K.F., Liu A.M.L., Poon R.T.P., Fan S.T., Chan K.L. and Luk J.M.C., Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma, Nature Genetics. 2012, 44(7): 765-769.


Researcher : Liu CL

Project Title:The significance of intra-graft expression profile and ultrastructural features at early phase after liver transplantation-a prospective study of liver transplantation using cadaver and live donors
Investigator(s):Liu CL, Man K
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Portal vein embolization before major right hepatic resection for hepatocellular carcinoma: a prospective randomized study
Investigator(s):Liu CL, Fan ST, Tso WK
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006




Researcher : Liu F

List of Research Outputs

Yang D., Sun Z., Chen Y. and Liu F., Reagents for Detection of Hypochlorous Acid, European Patent EP2134724B1, issued on September 28, 2011. 2011.


Researcher : Liu ML

List of Research Outputs

Liu M.L., Roles of microRNAs in hepatocellular carcinoma: biomarkers, metabolisms and pathway regulators, Thesis, Doctor of Philosophy, The University of Hong Kong. 2011.


Researcher : Liu X

Project Title:AACR Annual Meeting 2012 A hemoglobin-based oxygen carrier enhances chemotherapy in a rat orthotopic HCC model
Investigator(s):Liu X
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:04/2012


Project Title:Impact of autophagic pathway on hepatic sinusoidal endothelial cells following ischemia reperfusion injury
Investigator(s):Liu X, Man K
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:05/2012


List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Hao W., Chan I.H.Y., Liu X., Tang P.M.Y., Tam P.K.H. and Wong K.K.Y., Early post-operative interleukin-6 and tumour necrosis factor-α levels after single-port laparoscopic varicocelectomy in children, Pediatric Surgery International. 2012, 28(3): 281-286.
Kwan K.H.L., Liu X., Yeung K.W.K., Ho C.M., To M.K.T. and Wong K.K.Y., Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing, Nanomedicine: Nanotechnology, Biology and Medicine. 2011, 7(4): 497-504.
Lee P.Y., Zhang R., Li V., Liu X., Sun R.W.Y., Che C.M. and Wong K.K.Y., Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation, International Journal of Nanomedicine. 2012, 7: 731-737.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
To M.K.T., Yeung K.W.K., Wong K.K.Y., Liu X. and Kwan K.H.L., The Modulating Action of Silver Nanoparticles on Collagen Deposition in Producing Scarless Wound Healing, Australia Orthopaedic Association / New Zealand Orthopaedic Association Combined Annual Scientific Meeting. 2011.
To M.K.T., Wong K.K.Y., Yeung K.W.K., Kwan K.H.L. and Liu X., The Modulating Action of Silver Nanoparticles on Collagen Deposition in Producing Scarless Wound Healing, Tissue Engineering & Regenerative Medicine International Society. 2011.


Researcher : Liu X

List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Hao W., Chan I.H.Y., Liu X., Tang P.M.Y., Tam P.K.H. and Wong K.K.Y., Early post-operative interleukin-6 and tumour necrosis factor-α levels after single-port laparoscopic varicocelectomy in children, Pediatric Surgery International. 2012, 28(3): 281-286.
Kwan K.H.L., Liu X., Yeung K.W.K., Ho C.M., To M.K.T. and Wong K.K.Y., Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing, Nanomedicine: Nanotechnology, Biology and Medicine. 2011, 7(4): 497-504.
Lee P.Y., Zhang R., Li V., Liu X., Sun R.W.Y., Che C.M. and Wong K.K.Y., Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation, International Journal of Nanomedicine. 2012, 7: 731-737.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
To M.K.T., Yeung K.W.K., Wong K.K.Y., Liu X. and Kwan K.H.L., The Modulating Action of Silver Nanoparticles on Collagen Deposition in Producing Scarless Wound Healing, Australia Orthopaedic Association / New Zealand Orthopaedic Association Combined Annual Scientific Meeting. 2011.
To M.K.T., Wong K.K.Y., Yeung K.W.K., Kwan K.H.L. and Liu X., The Modulating Action of Silver Nanoparticles on Collagen Deposition in Producing Scarless Wound Healing, Tissue Engineering & Regenerative Medicine International Society. 2011.


Researcher : Liu X

List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Hao W., Chan I.H.Y., Liu X., Tang P.M.Y., Tam P.K.H. and Wong K.K.Y., Early post-operative interleukin-6 and tumour necrosis factor-α levels after single-port laparoscopic varicocelectomy in children, Pediatric Surgery International. 2012, 28(3): 281-286.
Kwan K.H.L., Liu X., Yeung K.W.K., Ho C.M., To M.K.T. and Wong K.K.Y., Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing, Nanomedicine: Nanotechnology, Biology and Medicine. 2011, 7(4): 497-504.
Lee P.Y., Zhang R., Li V., Liu X., Sun R.W.Y., Che C.M. and Wong K.K.Y., Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation, International Journal of Nanomedicine. 2012, 7: 731-737.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
To M.K.T., Yeung K.W.K., Wong K.K.Y., Liu X. and Kwan K.H.L., The Modulating Action of Silver Nanoparticles on Collagen Deposition in Producing Scarless Wound Healing, Australia Orthopaedic Association / New Zealand Orthopaedic Association Combined Annual Scientific Meeting. 2011.
To M.K.T., Wong K.K.Y., Yeung K.W.K., Kwan K.H.L. and Liu X., The Modulating Action of Silver Nanoparticles on Collagen Deposition in Producing Scarless Wound Healing, Tissue Engineering & Regenerative Medicine International Society. 2011.


Researcher : Liu Y

Project Title:The effects of FTY720 on suppression of circulating myeloid-derived suppressor cells/endothelial progenitor cells mobilization during tumor recurrence in a rat liver cancer model
Investigator(s):Liu Y, Man K, Lo CM
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2009




Researcher : Lo CM

Project Title:Post-operative adjuvant therapy with recombinant interferon-[alpha] following curative resection of hepatocellular carcinoma: a randomised dose-response controlled trial
Investigator(s):Lo CM, Fan ST
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:02/1999


Project Title:Development of anti-HBsAb in patients with chronic hepatitis B after liver transplantation using lamivudine prophylaxis: the possible role of adoptive immunity
Investigator(s):Lo CM
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:01/2000


Project Title:Tumor recurrence after living donor liver transplantation – the significance of small-for-size graft injury on mobilization of circulating cancer stem like cells/endothelial progenitor cells
Investigator(s):Lo CM, Man K, Liu Y
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2009


Project Title:Liver Transplantation Research Centre: A Multidisciplinary Study for Liver Graft Injury
Investigator(s):Lo CM, Man K, Guan X, Xu A
Department:Surgery
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2009
Completion Date:05/2012


Project Title:Angiopoietin-like protein 4 (ANGPLT4) as a novel therapy for liver cancer growth, metastasis and recurrence
Investigator(s):Lo CM, Man K
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2010
Completion Date:12/2011


Project Title:Recue marginal liver graft failure by stem cell therapy – the potential of tissue repair and the risk of tumor recurrence
Investigator(s):Lo CM, Man K
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


Project Title:Liver Transplantation Research Centre: A Multidisciplinary Study for Liver Graft Injury
Investigator(s):Lo CM, Man K, Guan X, Xu A, Lian Q
Department:Surgery
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2012


List of Research Outputs

Abdelmalek M.F., Humar A., Stickel F., Andreone P., Pascher A., Barroso E., Neff G.W., Ranjan D., Toselli L.T., Gane E.J., Scarola J., Alberts R.G., Maller E.S. and Lo C.M., Sirolimus conversion regimen versus continued calcineurin inhibitors in liver allograft recipients: a randomized trial, American Journal of Transplantation. 2012, 12(3): 694-705.
Chan A.C.Y., Poon R.T.P., Cheung T.T., Chok K.S.H., Chan S.C., Fan S.T. and Lo C.M., Survival analysis of re-resection versus radiofrequency ablation for intrahepatic recurrence after hepatectomy for hepatocellular carcinoma, World Journal of Surgery. 2011, Epub on 2011-10-27.
Chan S.C., Lo C.M., Chok K.S.H., Sharr W.W., Cheung T.T., Tsang S.H.Y., Chan A.C.Y. and Fan S.T., Modulation of graft vascular inflow guided by flowmetry and manometry in liver transplantation, Hepatobiliary & Pancreatic Diseases International. 2011, 10(6): 649-656.
Chan S.C., Fan S.T., Chok K.S.H., Cheung T.T., Chan A.C.Y., Fung J.Y.Y., Poon R.T.P. and Lo C.M., Survival advantage of primary liver transplantation for hepatocellular carcinoma within the up-to-7 criteria with microvascular invasion, Hepatology International. 2011, Epub on 2011-10-21.
Cheung T.T., Poon R.T.P., Yau T.C.C., Tsang D.S., Lo C.M. and Fan S.T., High-intensity focused ultrasound as a treatment for colorectal liver metastasis in difficult position (Letter to the Editor), International Journal of Colorectal Disease. 2011, Epub on 2011-08-13.
Cheung T.T., Chan S.C., Chok K.S.H., Chan A.C.Y., Yu W.C., Poon R.T.P., Lo C.M. and Fan S.T., Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma, Hepatobiliary & Pancreatic Diseases International. 2012, 11(3): 267-271.
Cheung T.T., Chu F.S., Jenkins C.R., Tsang D.S., Chok K.S.H., Chan A.C.Y., Yau T.C.C., Chan S.C., Poon R.T.P., Lo C.M. and Fan S.T., Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma, World Journal of Surgery. 2012, Epub on 2012-06-15.
Chok K.S.H., Fung J.Y.Y., Chan S.C., Cheung T.T., Sharr W.W., Chan A.C.Y., Fan S.T. and Lo C.M., Outcomes of living donor liver transplantation for patients with preoperative type 1 hepatorenal syndrome and acute hepatic decompensation, Liver Transplantation. 2012, Epub on 2012-01-30.
Chok K.S.H., Chan S.C., Poon R.T.P., Fan S.T. and Lo C.M., Re-resection for metachronous primary hepatocellular carcinoma: is it justified?, ANZ Journal of Surgery. 2012, 82(1-2): 63-67.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Fung J.Y.Y., Tsang S.H.Y., Fan S.T. and Lo C.M., Single-centre experience of liver transplantation for familial amyloidotic polyneuropathy of non-Val30Met variants in Chinese patients, Amyloid. 2012, 19(1): 33-36.
Dai W.C., Fan S.T., Cheung T.T., Chok K.S.H., Chan A.C.Y., Tsang S.H.Y., Poon R.T.P. and Lo C.M., The impact of family history of hepatocellular carcinoma on its patients' survival, Hepatobiliary & Pancreatic Diseases International. 2012, 11(2): 160-164.
Fung J.Y.Y., Chan S.C., Cheung C.K.Y., Chok K.S.H., Sharr W.W., Chan A.C.Y., Dai W.C., Cheung T.T., Fan S.T., Lai C.L., Yuen R.M.F. and Lo C.M., Entecavir Versus Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B., 18th Annual International Congress on ILTS Location: San Francisco, USA. May 16-19, 2012. Liver Transplantation.. 2012, 18 (supp 1): S124.
Fung J.Y.Y., Cheung C.K.Y., Chan S.C., Yuen R.M.F., Chok K.S.H., Sharr W.W., Dai W.C., Chan A.C.Y., Cheung T.T., Tsang S.H.Y., Lam B.K.Y., Lai C.L. and Lo C.M., Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation, Gastroenterology. 2011, 141(4): 1212-1219.
Fung J.Y.Y., Chan S.C., Yuen R.M.F., Lai C.L., Chok K.S.H., Sharr W.W., Dai W.C., Fan S.T. and Lo C.M., Long-term Outcome of Lamivudine Mono-prophylaxis After Liver Transplantation In Hepatitis B Patients , 62nd Annual Meeting Of The American-association-for-the-study-of-liver-diseases (AASLD) Location: San Francisco, USA. November 04-08, 2011. Hepatology . 2011, 54(Supp 1): 450A-450A.
Fung J.Y.Y. and Lo C.M., Reply (Correspondence) (Refers to: Combined prophylaxis might still be better than monoprophylaxis with entecavir following liver transplantation for hepatitis B), Gastroenterology. 2012, 142(1): e34-35.
Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Lo C.M., Associate Editor, 中華消化外科雜誌, 2012.
Lo C.M., Associate Editor, American Journal of Transplantation. 2012.
Lo C.M., Associate Editor, Digestive Surgery. 2012.
Lo C.M., Associate Editor, Liver International. 2012.
Lo C.M., Chairman of Nominating Committee (2011 – 2012), International Liver Transplantation Society. 2012.
Lo C.M., Council Member (2005 – Present), The College of Surgeons of Hong Kong. 2011.
Lo C.M., Council Member (July 2005 – Present), International Liver Transplantation Society. 2011.
Lo C.M., Council Member and Chairman of Liver Donation Committee (2010 – Present), The Hong Kong Liver Foundation. 2012.
Lo C.M., Course Director, ILTS “Innovations in Liver Transplantation: An International Effort” Conference, Beijing, China, 12-13 November 2011. 2011.
Lo C.M., Current trends in OLT in Hong Kong, The30th Annual Meeting of the Japanese Liver Transplantation Society, Fukuoka, Japan, 14-15 June 2012. 2012.
Lo C.M., Deputy Editor (2008 – 2011), Liver Transplantation. 2011.
Lo C.M., Director (2011 – Present), The Hong Kong Tuberculosis, Chest & Heart Diseases Association. 2012.
Lo C.M., Down-staging hepatocellular carcinoma for liver transplant, The 22nd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2012), Taipei, Taiwan, 16-19 February 2012. 2012.
Lo C.M., Downstaging of hepatocellular carcinoma prior to liver transplantation, Chinese Surgical Week 2011, Beijing, China, 7-10 September 2011. 2011.
Lo C.M., Examiner (2003 - present), MRCS examination, The College of Surgeons of Hong Kong. 2011.
Lo C.M., Examiner, Licentiate Examination, the Licentiate Committee (1995 – Present), Medical Council of Hong Kong. 2011.
Lo C.M., Governor – Hong Kong Chapter (2009 – Present), American College of Surgeons. 2012.
Lo C.M., Guest Professor (2002 – Present), The Peking University Health Science Centre, Peking University First Hospital, China. 2012.
Lo C.M., Guest Professor (2004 – Present), Army Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, China. 2012.
Lo C.M., Honorary Consultant (2002 – Present), Department of Surgery, Tung Wah Hospital, Hong Kong. 2011.
Lo C.M., Honorary Consultant (2002 – Present), King Faisal Hospital & Research Centre, Kingdom of Saudi Arabia. 2012.
Lo C.M., Honorary Consultant (2005 – Present), Hong Kong Sanatorium & Hospital. 2011.
Lo C.M., Honorary Fellow, American Surgical Association. 2012.
Lo C.M., Imune suppression in liver transplantation, The 8th APASL Single Topic Conference, Beijing, China, 7-9 October 2011. 2011.
Lo C.M., Issues involved in cadaveric liver transplantation, International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011. 2011.
Lo C.M., Liver Cancer, The Gastrointestinal Oncology Summit 2012, Hong Kong, 28-29 January 2012. 2012.
Lo C.M., Liver surgery (Video presentation), International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011.
Lo C.M., Member (2001 - present), Technology & Therapeutics Subcommittee, Queen Mary Hospital. 2011.
Lo C.M., Member (2002 – Present), Asian Pacific Digestive Week Federation. 2012.
Lo C.M., Member (2003 - present), Institutional Review Board of The University of Hong Kong / Hospital Authority Hong Kong West Cluster. 2011.
Lo C.M., Member of Ad Hoc Honorary Fellows Advisory Sub-committee, Region IV (East Asia) (2012 – April 2015), American Surgical Association. 2012.
Lo C.M., Member of Board of Directors (2011 – 2016), James IV Association of Surgeons. 2012.
Lo C.M., Member of Board of Examiners (2002 – Present), The College of Surgeons of Hong Kong. 2011.
Lo C.M., Member of Executive Committee (1998 – Present), International Society for Digestive Surgery. 2012.
Lo C.M., Member of International Scientific Committee (August 2010 – Present), The Transplantation Society. 2011.
Lo C.M., Member of Membership Committee (November 2010 – May 2013), The Society for Surgery of the Alimentary Tract. 2012.
Lo C.M., Member of Program Committee (1997 – Present), International Society for Digestive Surgery. 2012.
Lo C.M., Member of Program Committee (2006 – Present), International Liver Transplantation Society. 2012.
Lo C.M., Member of Scientific Committee (1998 – Present), Cheng Si Yuan China-International Hepatitis Research Foundation. 2012.
Lo C.M., Member, Editorial Board, Annals of Surgery. 2012.
Lo C.M., Member, Editorial Board, Hepatobiliary & Pancreatic Diseases International. 2012.
Lo C.M., Member, Editorial Board, Surgery. 2012.
Lo C.M., Member, Editorial Board, World Journal of Surgery. 2012.
Lo C.M., Member, Editorial Board, 中華普通外科雜誌. 2012.
Lo C.M., Member, Exemptions Sub-committee, the Licentiate Committee (2003 – Present), Medical Council of Hong Kong. 2012.
Lo C.M., Member, Hospital Governing Committee of the Gratham Hospital (November 2011 – March 2013), Hong Kong Hospital Authority. 2011.
Lo C.M., Member, Internship Sub-committee, the Licentiate Committee (2011 – Present), Medical Council of Hong Kong. 2012.
Lo C.M., Member, Panel of Assessors (2004 – Present), Medical Council of Hong Kong. 2012.
Lo C.M., Member, Regional Advisory Committee, Hong Kong Islands (April 2008 – March 2012), Hong Kong Hospital Authority. 2011.
Lo C.M., National Delegate (1998 – Present), International Society for Digestive Surgery. 2012.
Lo C.M., Optimal selection of surgical treatment for HCC in Asia, The APASL 2nd Hepatocellular Carcinoma Conference (9th APASL STC), Jeju, Korea, 1-3 December 2011. 2011.
Lo C.M., Prevention of recurrent hepatitis B after liver transplantation, The30th Annual Meeting of the Japanese Liver Transplantation Society, Fukuoka, Japan, 14-15 June 2012. 2012.
Lo C.M., Reviewer (1997 – Present), UICC Fellowship Selection Committee, International Union Against Cancer. 2012.
Lo C.M., Right lobe for adult liver transplantation, The ILTS 18th Annual International Congress, San Francisco, USA, 16-19 May 2012. 2012.
Lo C.M., Surgical management of hilar cholangiocarcinoma, Asian Pacific Digestive Week 2011, Singapore, 1-4 October 2011. 2011.
Lo C.M., Technical LDLT approach (anatomic variation), ILTS “Innovations in Liver Transplantation: An International Effort” Conference, Beijing, China, 12-13 November 2011. 2011.
Lo C.M., Treasurer (2008 – Present), Asian Pacific Digestive Week Federation. 2012.
Lo C.M., Visiting Professor (March 2010 – February 2012), The First Affiliated Hospital, Sun Yat-sen University, China. 2011.
Ma Y.Y., Li C., Law C.F.B.C., Lian Q., Man K. and Lo C.M., 2012Young Investigator Travel Award , 18th International Liver Transplantation Society Congress,may 16 - 19, 2012 San Francisco, Californa, USA Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration . Liver Transplantation, 2012, 18.
Ma Y.Y., Li C.X., Law B., Lian Q., Man K. and Lo C.M., Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration, Liver Transplantation. 2012, 18: S138-S139.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Man K., Wong N., Li C., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, Young Investigator Award, the 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012. 2012.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
Shen B., Chu E.S., Zhao G., Man K., Wu C.W., Cheng J.T., Li G., Nie Y. and Lo C.M., PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice, British Journal of Cancer. 2012, 106(9): 1486-1494.
Siriwardana R.C., Chan S.C., Chok K.S.H., Lo C.M. and Fan S.T., Effects of the liver volume and donor steatosis on errors in the estimated standard liver volume, Liver Transplantation. 2011, 17(12): 1437-1442.
Tang K.H., Ma S.K.Y., Lee K.W., Chan Y.P., Kwan P.S., Tong M., Ng I.O.L., Man K., To K.F., Lai P.B., Lo C.M., Guan X. and Chan K.W., CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling, Hepatology. 2011, 55(3): 807-820.
Wang X., Lo C.M. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver (Abstract), The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.
Ye D., Li F.Y.L., Lam K.S.L., Li H., Jia W., Wang Y., Man K., Lo C.M., Li X. and Xu A., Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice, Gut. 2012.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Lo CY

Project Title:Establishment of a comprehensive service and registry for hereditary familial endocrinopathy syndromes in Hong Kong
Investigator(s):Lo CY, Lam KSL
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2005


List of Research Outputs

Lang B.H.H., Yih P.C. and Lo C.Y., A review of risk factors and timign for postoperative hematoma after thyroidectomy: is outpatient thyroidectomy really safe?, World Journal of Surgery. 2012, Epub ahead of print.
Lang B.H.H., Wong I.Y., Wong K.P. and Lo C.Y., Eucalcemic parathyroid hormone elevation after parathyroidectomy for primary sporadic hyperparathyroidism: risk factors, trend, and outcome, Annals of Surgical Oncology. 2011, Epub ahead of print.
Lang B.H.H., Yih P.C., Shek T.W., Wan K.Y. and Lo C.Y., Factors affecting the adequacy of lymph node yield in prophylactic unilateral central neck dissection for papillary thyroid carcinoma, Journal of Surgical Oncology. 2012, Epub ahead of print.
Lang B.H.H., Wong K.P., Wan K.Y. and Lo C.Y., Significance of metastatic lymph node ratio on stimulated thyroglobulin levels in papillary thyroid carcinoma after prophylactic unilateral central neck dissection, Annals of Surgical Oncology. 2011, Epub ahead of print.
Lang B.H.H., Tang A.H., Wong K.P., Shek T.W., Wan K.Y. and Lo C.Y., Significance of size of lymph node metastasis on postsurgical stimulated thyroglobulin levels after prophylactic unilateral central neck dissection in papillary thyroid carcinoma, Annals of Surgical Oncology. 2012, Epub ahead of print.


Researcher : Lo OSH

List of Research Outputs

Law W.L., Poon T.C.J., Fan J.K.M. and Lo O.S.H., Survival following laparoscopic versus open resection for colorectal cancer, International Journal of Colorectal Disease. 2012, Epub ahead of print.
Poon J.T.C., Law W.L., Chow L.C., Fan J.K.M. and Lo O.S.H., Outcome of laparoscopic resection for colorectal cancer in patients with high operative risk, Annals of Surgical Oncology. 2011, 18(7): 1884-1890.
Poon T.C.J., Cheung C.W., Law W.L., Fan J.K.M. and Lo O.S.H., A randomized controlled trial comparing the outcomes of patients who undergo single port laparoscopic colectomy and conventional laparoscopic colectomy, SAGES 2012, San Diego, California. 7-10 March . 2012.
Poon T.C.J., Cheung C.W., Fan J.K.M., Lo O.S.H. and Law W.L., Single incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized controlled trial, The Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting 2012, San Diego, California, U.S.A., 7 - 10 March 2012.
Poon T.C.J., Cheung C.W., Fan J.K.M., Lo O.S.H. and Law W.L., Single-incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized, controlled trial, Surgical endoscopy. 2012, Epub ahead of print.
She W.H., Poon T.C.J., Fan J.K.M., Lo O.S.H. and Law W.L., Stoma reversal in patients who underwent low anterior resection and diversion stoma for rectal cancer, Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.


Researcher : Lu P

List of Research Outputs

Wang X., Zhang W., Lui E.L.H., Zhu Y., Lu P., Yu X., Sun J., Yang S., Poon R.T.P. and Fan S.T., Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma, International Journal of Cancer. 2011, 131(3): E163-172.


Researcher : Lui ELH

List of Research Outputs

Wang X., Zhang W., Lui E.L.H., Zhu Y., Lu P., Yu X., Sun J., Yang S., Poon R.T.P. and Fan S.T., Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma, International Journal of Cancer. 2011, 131(3): E163-172.


Researcher : Lui VCH

Project Title:15th International Society of Development Biologists Congress (ISDB 2005) Perturbation of Hoxb5 Signalling in Vagal Neural Crest Cells Causes Defective Development of the Enteric Nervous System
Investigator(s):Lui VCH
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2005


Project Title:HOXB5 and RET promoter: regulation of RET transcription in Hirschsprungs disease
Investigator(s):Lui VCH, Garcia-Barcelo MM, Tam PKH
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2008
Completion Date:09/2011


Project Title:Wif-1 regulates cloaca septation via Wnt signaling in urorectal development
Investigator(s):Lui VCH
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010
Completion Date:08/2011


Project Title:Cooperation of HOXB5 and SOX10 in the regulation of RET expression
Investigator(s):Lui VCH, Garcia-Barcelo MM
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2011


Project Title:Transcriptional regulation of RET in Hirschsprungs disease'
Investigator(s):Lui VCH, Garcia-Barcelo MM, Tam PKH
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2011


Project Title:Characterisation of the molecular events leading to urorectal defects in Wif1-/- (Wnt inhibitory factor 1-/-) mice
Investigator(s):Lui VCH
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Cheung P.F.Y., Cheng C.K.C., Wong C.L., Ho J.C.Y., Yip C.W., Lui V.C.H., Cheung A.N.Y., Fan S.T. and Cheung S.T., Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells, PLoS One. 2011, 6(12): e28246.
Kam K.M., Lee K.Y., Tam P.K.H. and Lui V.C.H., Generation of NSE-MerCreMer transgenic mice with tamoxifen inducible Cre activity in neurons, PLoS One. 2012, 7(5): e35799.
Kam K.M., Cheung M.C.H., Tam P.K.H. and Lui V.C.H., Hoxb5 trans-activates Sox9 and regulates trunk neural crest cell development, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
Leon Y.Y., So M.T., Lui V.C.H., Hofstra R.M.W., Tam P.K.H., Ngan E.S.W. and Garcia-Barcelo M.M., Functional analyses of RET mutations in Chinese Hirschsprung disease patients, Birth Defects Research (Part A): Clinical and Molecular Teratology. 2012, 94(1): 47-51.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Ngan E.S.W., Garcia-Barcelo M.M., Yip B.H.K., Poon P.C., Lau C.S.T., Kwok K.M., Sat E.W.Y., Sham M.H., Wong K.K.Y., Wainwright B.J., Cherny S.S., Hui C.C., Sham P.C., Lui V.C.H. and Tam P.K.H., Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung’s disease in mice and humans, Journal of Clinical Investigation. 2011, 121(9): 3467-3478.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
Wang X., Chan K.K., Lui V.C.H. and Norbury C., G1 checkpoint establishment and associated DNA repair kinetics in vivo during embryonic liver development (Abstract), ISSCR Annual Meeting 2012, Yokohama, Japan, 13 June 2012.
Zhang M., Leung C., Sit H.M., Chu K.H., Lui V.C.H., Tam P.K.H. and Sham M.H., Sox10 NGFP mutation affects migration of enteric neural cress cells in mouse embryonic gut, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March, 2012.
Zhu J., Garcia-Barcelo M.M., Tam P.K.H. and Lui V.C.H., RET transcriptional regulation by HOXB5 in Hirschsprung's disease, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.


Researcher : Lui WM

List of Research Outputs

Chong B.H., Lau K.K., Chan K.H., Lui W.M., Leung G.K.K., Lau C.P., Tse H.F., Pu J.K.S. and Siu C.W., Use of aspirin in Chinese after recovery from primary intracranial haemorrhage, Thrombosis and Haemostasis. 2012, 107(2): 241-247.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in human malignant gliomas: a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide, The Society for NeuroOncology. 2011.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in malignant gliomas - a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide (P4HB) (Abstract), Neuro-oncology. 2011, 13(3): 111.
Leung G.K.K., Lui W.M., Yuen M.M.A., Chow W.S. and Tse P.Y.H., An endoscopic modification of the simultaneous 'above and below' approach to large pituitary adenomas, Pituitary 2012. 2012, 15(2): 237-241.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Identifying molecular candidates associated with acquired temozolomide resistance in human malignant glioma - a proteomics approach., The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Leung G.K.K. and Lui W.M., Pure endonasal endoscopic transsphenoidal surgery - an endocrinologist-led assessment of a single-surgeon's experience, 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Li L.F., Tse Y.H., Ho S.L., Yan K.W. and Lui W.M., Duodenal GIST metastasized to skull and orbit managed by surgery - a case report, Asian Journal of Surgery. 2012, 34(4): 181-184.
Pong V., Chan K.H., Chong B.H., Lui W.M., Leung G.K.K., Tse H.F., Pu J.K.S. and Siu D.C.W., Long-term outcome and prognostic factors after spontaneous cerebellar hemorrhage. , Cerebellum. 2012.
Sun S., Wong S.T.S., Zhang X., Pu J.K.S., Lee N.P.Y., Day P.J., Ng K.B., Lui W.M. and Leung G.K.K., Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines , Journal of Neuro-oncology. 2012, 107(1): 89-100.
Taw B.B.T., Lam A.C.S., Hung K.N., Lui W.M., Leung G.K.K. and Ho F.L.Y., Functional survival after acute care for severe head injury at a designated trauma center in Hong Kong, Asian Journal of Surgery. 2012, Epub 06-06-2012.
Taw B.T., Lee V.H.F., Hung K.N., Ng C.Y. and Lui W.M., The efficacy and safety of LINAC stereotactic radiosurgery booster after whole brain radiotherapy for cerebral metastases , XXth ESSFN conference in 2011.
Tsang C.O., Leung K.M., Leung G.K.K. and Lui W.M., Carotid blowout syndrome: EC-IC bypass and endovascular management of ruptured radiation-related pseudoaneurym in nasopharyngeal cancer patients, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Tsang C.O.A., Leung G.K.K. and Lui W.M., Best Oral Free Paper in General Neurosurgery (non-HST), The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011. 2011.
Zhang X., Sun S., Pu J.K.S., Tsang C.O.A., Lee D., Lui W.M., Wong S.T.S., Leung G.K.K. and Man V.O.Y., Long non-coding RNA expression profiles predict clinical phenotypes in glioma, Neurobiology of Disease. 2012, 48(1): 1-8.


Researcher : Luk JMC

Project Title:Investigating Liver Intestine-Cadherin Function In Hepatocellular Carcinoma
Investigator(s):Luk JMC, Lee NPY, Ng IOL, Fan ST
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:12/2005


Project Title:Liver cancer biomarker test: diagnostic use of CDH17 monoclonal antibodies
Investigator(s):Luk JMC
Department:Surgery
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:10/2007


List of Research Outputs

Fatima S., Lee N.P.Y., Tsang F.H., Kolligs F.T., Ng I.O.L., Poon R.T.P., Fan S.T. and Luk J.M.C., Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway by influencing β-catenin in hepatocellular carcinoma, Oncogene. 2012, Epub on 2012-01-16.
Fatima S., Lee N.P.Y. and Luk J.M.C., Dickkopfs and Wnt/β-catenin signalling in liver cancer, World Journal of Clinical Oncology. 2011, 2(8): 311-325.
Hao K., Lamb J., Zhang C., Xie T., Wang K., Zhang B., Chudin E., Lee N.P.Y., Mao M., Zhong H., Greenawalt D., Ferguson M.D., Ng I.O.L., Sham P.C., Poon R.T.P., Molony C., Schadt E.E., Dai H. and Luk J.M.C., Clinicopathologic and gene expression parameters predict liver cancer prognosis, BMC Cancer. 2011, 11(1): 481.
Hui K.C., Chan K.W., Luk J.M.C., Lee N.P.Y., Chung M.F.Y., Cheung C.M., Srivastava G., Tsao G.S.W., Tang J.C.O. and Law S.Y.K., Cytoplasmic Forkhead Box M1 (FoxM1) in esophageal squamous cell carcinoma significantly correlates with pathological disease stage, World Journal of Surgery. 2012, 36(1): 90-97.
Ivanovska I., Zhang C., Liu A.M.L., Wong K.F., Lee N.P.Y., Lewis P., Philippar U., Bansal D., Buser C., Scott M., Mao M., Poon R.T.P., Fan S.T., Cleary M.A., Luk J.M.C. and Dai H., Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma, PLoS One. 2011, 6(9): e24582.
Lamb J.R., Zhang C., Xie T., Wang K., Zhang B., Hao K., Chudin E., Fraser H.B., Millstein J., Ferguson M., Suver C., Ivanovska I., Scott M., Poon R.T.P., Fan S.T., Yeung C., Lee N.P.Y. and Luk J.M.C., Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting, PLoS One. 2011, 6(7): e20090.
Lee N.P.Y., Wang Y. and Luk J.M.C., Monoclonal antibody against cadherin-17 as a potential treatment for liver cancer (Poster & Abstract), The 47th Annual Meeting of the European Association for the Study of the Liver and the International Liver Congress 2012, Barcelona, Spain, 18-22 April 2012.
Liu A.M.L., Yao T., Wang W., Wong K.F., Lee N.P.Y., Fan S.T., Poon R.T.P., Gao C. and Luk J.M.C., Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study, BMJ Open. 2012, 2(2): e000825.
Lu W.J., Lee N.P.Y., Wadhwa R. and Luk J.M.C., Mortalin-p53 interaction as a target for liver cancer therapy (Chapter 17), Mortalin Biology: Life, Stress and Death. Editors: Kaul SC and Wadhwa R. not known, Springer, 2012, not applicable: not known.
Luk J.M.C., Burchard J., Zhang C., Liu A.M.L., Wong K.F., Shek H.P., Lee N.P.Y., Fan S.T., Poon R.T.P., Ivanovska I., Philippar U., Cleary M.A., Buser C.A., Shaw P.M., Lee C.N., Tenen D.G., Dai H. and Mao M., DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival, Journal of Biological Chemistry. 2011, 286(35): 30706-30713.
Shek H.P., Luk J.M.C. and Lee N.P.Y., Targeting serine peptidase inhibitor, Kazal type 1 (SPINK1) as a potential treatment for hepatocellular carcinoma (Poster and Abstract), The 5th Annual Conference of the International Liver Cancer Association, Hong Kong, 2-4 September 2011.
Sung W.K., Zheng H., Li S., Chen R., Liu X., Li Y., Lee N.P.Y., Lee W.H., Wong K.F., Liu A.M.L., Poon R.T.P., Fan S.T., Chan K.L. and Luk J.M.C., Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma, Nature Genetics. 2012, 44(7): 765-769.
Tung K.K., Mak K.M., Fatima S., Lo C.L.R., Zhao H., Zhang C., Dai H., Poon R.T.P., Yuen R.M.F., Lai C.L., Li J.J., Luk J.M.C. and Ng I.O.L., Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma, Liver International. 2011, 31(10): 1494-1504.


Researcher : Ma YY

List of Research Outputs

Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Ma Y.Y., Li C., Law C.F.B.C., Lian Q., Man K. and Lo C.M., 2012Young Investigator Travel Award , 18th International Liver Transplantation Society Congress,may 16 - 19, 2012 San Francisco, Californa, USA Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration . Liver Transplantation, 2012, 18.
Ma Y.Y., Li C.X., Law B., Lian Q., Man K. and Lo C.M., Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration, Liver Transplantation. 2012, 18: S138-S139.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.


Researcher : Man K

Project Title:The role of tumor associated macrophages (TAMs) on tumor growth and metastasis of hepatocellular carcinoma
Investigator(s):Man K, Lo CM
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:03/2011


Project Title:Circulating protein marker for predicting and preventing tumor recurrence after liver tansplantation for hepatocellular carcinoma patients (ITS/003/11)
Investigator(s):Man K, Ng KTP, Liu X, Lo CM
Department:Surgery
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:Circulating protein marker for predicting and preventing tumor recurrence after liver tansplantation for hepatocellular carcinoma patients
Investigator(s):Man K, Ng KTP, Liu X, Lo CM
Department:Surgery
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:01/2012


Project Title:The circulating endothelial progenitor cells mobilized by surgical stress - the potential of tissue repair and the risk of tumor recurrence
Investigator(s):Man K, Lo CM
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:18th Annual Congress of International Liver Transplantation Society (ILTS) Acute Phase Liver Graft Injury Mobilizes Regulating B cells after LDLT for HCC Patients Through TLR4/CXCL10/CXCR3 Signaling
Investigator(s):Man K
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2012
Completion Date:05/2012


Project Title:Distinct liver regeneration pattern and molecular mechanism of marginal grafts after transplantation
Investigator(s):Man K, Lo CM, Liu X
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Chow A.M.K., Gao S., Fan S., Qiao Z., Lee Y.H., Yang J., Man K. and Wu E.X., Liver fibrosis: an intravoxel incoherent motion (IVIM) study, Journal of Magnetic Resonance Imaging. 2012, 36(1): 159-167.
Chow A.M.K., Gao S., Fan S., Qiao Z., Lee Y.H., Yang J., Man K. and Wu E.X., Measurement of liver T(1) and T(2) relaxation times in an experimental mouse model of liver fibrosis, Journal of Magnetic Resonance Imaging. 2012, 36(1): 152-158.
Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Ma Y.Y., Li C., Law C.F.B.C., Lian Q., Man K. and Lo C.M., 2012Young Investigator Travel Award , 18th International Liver Transplantation Society Congress,may 16 - 19, 2012 San Francisco, Californa, USA Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration . Liver Transplantation, 2012, 18.
Ma Y.Y., Li C.X., Law B., Lian Q., Man K. and Lo C.M., Novel Mechanism for Tissue Repair of Human Induced Pluripotent Stem Cells Derived Mesenchymal Stem Cells during Liver Regeneration, Liver Transplantation. 2012, 18: S138-S139.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Man K., Reviewer, Transplantation. 2011.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Man K., Wong N., Li C., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, Young Investigator Award, the 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012. 2012.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
Shen B., Chu E.S., Zhao G., Man K., Wu C.W., Cheng J.T., Li G., Nie Y. and Lo C.M., PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice, British Journal of Cancer. 2012, 106(9): 1486-1494.
Tang K.H., Ma S.K.Y., Lee K.W., Chan Y.P., Kwan P.S., Tong M., Ng I.O.L., Man K., To K.F., Lai P.B., Lo C.M., Guan X. and Chan K.W., CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling, Hepatology. 2011, 55(3): 807-820.
Tse E.Y.T., Ko F.C.F., Tung K.K., Chan L.K., Lee K.W., Ngan E.S.W., Man K., Wong A.S.T., Ng I.O.L. and Yam J.W.P., Caveolin-1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis, Journal of Pathology. 2011, 226(4): 645-653.
Wang N., Feng Y., Lau E.P., Tsang C.M., Ching Y.P., Man K., Tong Y., Nagamatsu T., Su W. and Tsao G.S.W., F-actin reorganization and inactivation of rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration., Integrate Cancer Therapy. 2011.
Wang N., Feng Y., Zhu M., Tsang C.M., Man K., Tong Y. and Tsao G.S.W., Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism, Journal of cellular biochemistry. 2011.
Wang Y., Wong G.T.C., Man K. and Irwin M.G., British Journal of Anaesthesia. 2012, 109: 529-39.
Yau W.L., Pang R.W.C., Lee K.W., Lam C.S.C., Wo Y.H., Ng L., Chan J.Y.K., Chow A.K.M., Ng K.T.P., Man K. and Poon R.T.P., Overexpression of miR106b promotes metastasis in hepatocellular carcinoma by activating epithelial mesenchymal transition process, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.
Ye D., Li F.Y.L., Lam K.S.L., Li H., Jia W., Wang Y., Man K., Lo C.M., Li X. and Xu A., Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice, Gut. 2012.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Man OY

List of Research Outputs

Man O.Y., A comparative study of circulating microRNAs in nasopharyngeal carcinoma patients, Dissertation, Master of Philosophy, The University of Hong Kong. 2012.


Researcher : Miao X

List of Research Outputs

So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.


Researcher : Ming X

List of Research Outputs

Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.


Researcher : Ng EKO

Project Title:Differential expression of tumor-derived exosomal microRNAs from the plasma of breast cancer patients: A potential biomarker for breast cancer screening
Investigator(s):Ng EKO, Kwong A, Suen TKD
Department:Surgery
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:10/2009


Project Title:Development of a Novel Non-coding RNA-based Blood Test for Early Detection, Prognostication and/or Treatment Monitoring of Breast Cancer
Investigator(s):Ng EKO, Kwong A
Department:Surgery
Source(s) of Funding:Matching Grant for Joint Research
Start Date:09/2011


Project Title:An investigation into the presence of breast tumor-associated small non-coding RNAs from circulating exosomes
Investigator(s):Ng EKO, Kwong A
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:Science and the City - Pathology Update 2012 Noninvasive microRNA signatures from the plasma of breast cancer patients reveals sensitive and specific marker for breast cancer screening
Investigator(s):Ng EKO
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:03/2012


List of Research Outputs

Ng E.K.O., Appointed Assessor, Hong Kong Laboratory Accreditation Scheme, The Hong Kong Accreditation Service, Hong Kong. 2012.
Ng E.K.O., Member of Editorial Board, International Scholarly Research Network (ISRN) Virology. 2012.
Ng E.K.O., Molecular techniques II, Molecular Pathology Series, the American Society for Clinical Pathology International. 2011.
Ng E.K.O., Molecular techniques for mutation screening and their applications, Department of Pathology and Clinical Biochemistry, Queen Mary Hospital, Hong Kong. 2011.
Ng E.K.O., Leung P.H.C., Shin V.Y., Wong L.P., Ma E.S.K., Jin H.C., Chu K.M. and Kwong A., Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients, PLoS One. 2011, 6(7): e22233.
Yip W.K., Cheng A.S., Zhu R., Lung R.W., Tsang D.P., Lau S.S., Chen Y., Sung J.G., Lai P.B., Ng E.K.O., Yu J., Wong N., To K.F., Wong V.W., Sung J.J. and Chan H.L., Carboxyl-Terminal Truncated HBx Regulates a Distinct MicroRNA Transcription Program in Hepatocellular Carcinoma Development, PLoS One. 2011, 6(8): e22888.


Researcher : Ng KB

List of Research Outputs

Sun S., Wong S.T.S., Zhang X., Pu J.K.S., Lee N.P.Y., Day P.J., Ng K.B., Lui W.M. and Leung G.K.K., Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines , Journal of Neuro-oncology. 2012, 107(1): 89-100.


Researcher : Ng KKC

List of Research Outputs

Wood B.J., Poon R.T.P., Locklin J.K., Dreher M.R., Ng K.K.C. and Eugeni M., Phase I study of heat-deployed liposomal doxorubicin during radiofrequency ablation for hepatic malignancies, Journal of Vascular and Interventional Radiology. 2011, Epub on 2011-12-16.


Researcher : Ng KO

Project Title:Differential expression of tumor-derived exosomal microRNAs from the plasma of breast cancer patients: A potential biomarker for breast cancer screening
Investigator(s):Ng EKO, Kwong A, Suen TKD
Department:Surgery
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:10/2009


Project Title:Development of a Novel Non-coding RNA-based Blood Test for Early Detection, Prognostication and/or Treatment Monitoring of Breast Cancer
Investigator(s):Ng EKO, Kwong A
Department:Surgery
Source(s) of Funding:Matching Grant for Joint Research
Start Date:09/2011


Project Title:An investigation into the presence of breast tumor-associated small non-coding RNAs from circulating exosomes
Investigator(s):Ng EKO, Kwong A
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:Science and the City - Pathology Update 2012 Noninvasive microRNA signatures from the plasma of breast cancer patients reveals sensitive and specific marker for breast cancer screening
Investigator(s):Ng EKO
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:03/2012


List of Research Outputs



Researcher : Ng KTP

Project Title:Identification of molecular targets to overcome drug resistance in hepatocellular carcinoma
Investigator(s):Ng KTP, Man K
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:03/2012


Project Title:ILTS 18th Annual International Congress Acute phase circulating micoRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation
Investigator(s):Ng KTP
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2012
Completion Date:05/2012


List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Ng K.T.P., Man K., Wong N., Li C., Liu X., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Ng K.T.P., Man K., Wong N., Li C., Chan S.C. and Lo C.M., Acute phase circulating microRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation, Young Investigator Award, the 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012. 2012.
Yau W.L., Pang R.W.C., Lee K.W., Lam C.S.C., Wo Y.H., Ng L., Chan J.Y.K., Chow A.K.M., Ng K.T.P., Man K. and Poon R.T.P., Overexpression of miR106b promotes metastasis in hepatocellular carcinoma by activating epithelial mesenchymal transition process, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Ng L

List of Research Outputs

Ng L., Actopaxin: a novel regulator of cell migration and invasion in human hepatocellular carcinoma, Thesis, Doctor of Philosophy, The University of Hong Kong. 2012.
Yau W.L., Pang R.W.C., Lee K.W., Lam C.S.C., Wo Y.H., Ng L., Chan J.Y.K., Chow A.K.M., Ng K.T.P., Man K. and Poon R.T.P., Overexpression of miR106b promotes metastasis in hepatocellular carcinoma by activating epithelial mesenchymal transition process, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.


Researcher : Ng NP

List of Research Outputs

Fan S.T., Yang Z., Ho D.W.Y., Ng N.P., Yu W.C. and Wong J., Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study, Annals of Surgery. 2011, 254(4): 569-576.
Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Lam C.T., Yang Z., Ng N.P., Wan T.M.H., Lau J.C.S., Ho D.W.Y., Fan S.T. and Poon R.T.P., The potential role of CD44 in liver regeneration, The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.


Researcher : Ng TP

Project Title:Identification of molecular targets to overcome drug resistance in hepatocellular carcinoma
Investigator(s):Ng KTP, Man K
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:03/2012


Project Title:ILTS 18th Annual International Congress Acute phase circulating micoRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation
Investigator(s):Ng KTP
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2012
Completion Date:05/2012


List of Research Outputs



Researcher : Ng WM

List of Research Outputs

Chan Y.W., Ng W.M. and Wei W.I., Anatomical study and clinical applications of free posterior tibial flap in the Head and Neck region, Plastic and Reconstructive Surgery. 2011, 128(3): 131e-139e.


Researcher : Ngan ESW

Project Title:Thyroid transcription factor-1 (TTF-1), a potential susceptibility gene for familial papillary thyroid carcinoma
Investigator(s):Ngan ESW, Garcia-Barcelo MM, Khoo US, Lang BHH, Tam PKH
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2009
Completion Date:12/2011


Project Title:Prokineticin signaling in neuroblastoma
Investigator(s):Ngan ESW, Chan GCF, Tam PKH
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010
Completion Date:12/2011


Project Title:Implication of Hedgehog signaling in premature gliogenesis of neural crest cells
Investigator(s):Ngan ESW
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010
Completion Date:02/2012


Project Title:Premature gliogenesis of enteric neural crest cells induced by aberrant Sonic hedgehog-Notch signalling: a cause of Hirschsprung disease?
Investigator(s):Ngan ESW, Garcia-Barcelo MM, Tam PKH, Wong KKY
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2010


Project Title:Use of human iPSC-derived neural crest for studying functional implications of RET mutations identified in Hirschsprung’s patient
Investigator(s):Ngan ESW
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2011


Project Title:Roles of c-KIT expressing cells in neuroblastoma heterogeneity
Investigator(s):Ngan ESW
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


Project Title:ISSCR 10th Annual Meeting iPS cell-derived neural crest cells from a patient with Hirschsprung's disease show a reduced differentiation plasticity
Investigator(s):Ngan ESW
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2012
Completion Date:06/2012


List of Research Outputs

Chow H.M., Tam P.K.H. and Ngan E.S.W., Neural crest and Hirschsprung’s disease, In: Srivastava R.K. and Shankar S. (eds.), Stem Cell and Human Diseases. New York, Springer, 2011, 353-386.
Chow H.M., Yung S.Y.J. and Ngan E.S.W., Neural crest derived from Hirschsprung iPS cells show a reduced neural plasticity, Days of Molecular Medicine 2011, Hong Kong, 10-12 November 2011.
Lau S.T., Kwok C.K.M., Tam P.K.H. and Ngan E.S.W., Dynamic regulation of c-KIT population in neuroblastoma, The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Leon Y.Y., So M.T., Lui V.C.H., Hofstra R.M.W., Tam P.K.H., Ngan E.S.W. and Garcia-Barcelo M.M., Functional analyses of RET mutations in Chinese Hirschsprung disease patients, Birth Defects Research (Part A): Clinical and Molecular Teratology. 2012, 94(1): 47-51.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Ngan E.S.W., Dynamic regulation of c-KIT expressing cells in neuroblastoma (Invited Lecture), The 53th Japanese Society Meeting of Peditric Hematology/Oncology, Maebashi-City, Gunma, Japan, 25 - 27 November 2011.
Ngan E.S.W., Grant Reviewer, Odysseus project of the Research Foundation - Flanders (Belgium) (FWO). 2012.
Ngan E.S.W., Hedgehog-Notch induced premature gliogenesis: a new disease mechanism for Hirschsprung's disease (Invited Lecture), The 3rd International Symposium on Development of the Enteric Nervous System, Hong Kong, 25 - 28 March 2012. 2012.
Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., Hedgehog-Notch induced premature gliogenesis: a new disease mechanism for Hirschsprung's disease., The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
Ngan E.S.W., Garcia-Barcelo M.M., Yip B.H.K., Poon P.C., Lau C.S.T., Kwok K.M., Sat E.W.Y., Sham M.H., Wong K.K.Y., Wainwright B.J., Cherny S.S., Hui C.C., Sham P.C., Lui V.C.H. and Tam P.K.H., Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung’s disease in mice and humans, Journal of Clinical Investigation. 2011, 121(9): 3467-3478.
Ngan E.S.W., Niche for neuroblastoma (Invited Lecture), Croucher Advanced Study Institute 2012, Tumour Microenvironment - New Concepts and Molecular Mechanisms, Hong Kong, 9 - 13 January 2012. 2012.
Ngan E.S.W., Outstanding Research Paper Award 2011 (Paper title not provided), Department of Surgery, The University of Hong Kong. 2011.
Ngan E.S.W., Reviewer, Journal of Medical Genetics. 2012.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
Tse E.Y.T., Ko F.C.F., Tung K.K., Chan L.K., Lee K.W., Ngan E.S.W., Man K., Wong A.S.T., Ng I.O.L. and Yam J.W.P., Caveolin-1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis, Journal of Pathology. 2011, 226(4): 645-653.
Yung S.Y.J., Tse H.F., Tam P.K.H. and Ngan E.S.W., Establishing a patient-specific iPSC model for Hirschsprung’s disease and other neural crest-associated diseases, The 10th Annual Meeting of the International Society for Stem Cell Research, Yokohama, Japan, 13 - 16 June 2012.
Yung S.Y.J., Chow H.M., Tse H.F., Tam P.K.H. and Ngan E.S.W., Generation of patient-specific iPSCs for Hirschsprung's disease modelling, Days of Molecular Medicine 2011, Hong Kong, 10-12 November 2011.
Yung S.Y.J., Tse H.F., Wan T.S.K., Tam P.K.H. and Ngan E.S.W., Modelling Hirschsprung’s disease using patient-specific iPS cells, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25 - 28 March 2012.
Yung S.Y.J., Tse H.F., Tam P.K.H. and Ngan E.S.W., iPS cell-derived neural crest cells from a patient with Hirschsprung's disease show a reduced differentiation plasticity, The 10th Annual Meeting of the International Society for Stem Cell Research, Yokohama, Japan, 13 - 16 June 2012.


Researcher : Pang RWC

Project Title:A study of the modulatory effects of p53 on Pin1-mediated tumor growth, invasion and metastasis in hepatocellular carcinoma
Investigator(s):Pang RWC, Kwong YL, Tse EWC
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2008
Completion Date:11/2011


Project Title:Study of a novel role of Pin1 in regulating invasiveness and metastasis of hepatocellular carcinoma via Rho signaling
Investigator(s):Pang RWC, Kwong YL, Tse EWC
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


Project Title:A study on the functional role of a novel focal adhesion protein Actopaxin and its potential regulation by Pin1 in hepatocellular carcinoma
Investigator(s):Pang RWC
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Chiu J., Tang Y.F., Yao T.J., Wong A., Wong H., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Fan S.T., Poon R.T.P. and Yau T.C.C., The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: A retrospective analysis of efficacy, safety, and survival benefits, Cancer. 2012, Epub on 2012-04-19.
Chiu J.W., Pang R.W.C., Poon R.T.P. and Yau T.C.C., Systemic management of advanced hepatocellular carcinoma patients: the role of multi-targeted anti-angiogenic inhibitors, In: Lau J.W.Y. (ed.), Hepatocellular Carcinoma - Clinical Research. Shanghai, InTech, 2011, 309-320.
Pang R.W.C., Outstanding Young Researcher Award, The Univeristy of Hong Kong. 2012.
Pang R.W.C., Reserach Output Prize, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2011.
Tan V.P.Y., Wong W.M., Cheung T.K., Lai K.C., Chan P., Pang R.W.C. and Wong B.C.Y., Treatment Of Non-erosive Reflux Disease With A Proton Pump Inhibitor In Chinese Patients: A Randomized Controlled Trial., In: T. Azuma, Journal of Gastroenterology. Wiley InterScience, 2011, 46(7): 906-12.
Wong H., Tang Y.F., Yao T., Chiu J., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Poon R.T.P., Fan S.T. and Yau T.C.C., The outcomes and safety of single-agent sorafenib in the treatment of elderly patients with advanced hepatocellular carcinoma (HCC), Oncologist. 2011, 16(12): 1721-1728.
Yau T.C.C., Cheng P.N., Chan P., Chan W.Y.L., Chen L., Yuen J., Pang R.W.C., Fan S.T. and Poon R.T.P., A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma, Investigational New Drugs. 2012, Epub on 2012-03-17.
Yau T.C.C., Wong H., Chan P., Yao T., Pang R.W.C., Cheung T.T., Fan S.T. and Poon R.T.P., Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease, Investigational New Drugs. 2012, Epub on 2012-03-09.
Yau T.C.C., Yao T.J., Chan P., Wong H., Pang R.W.C., Fan S.T. and Poon R.T.P., The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib, Oncologist. 2011, Epub on 2011-09-01.
Yau W.L., Pang R.W.C., Lee K.W., Lam C.S.C., Wo Y.H., Ng L., Chan J.Y.K., Chow A.K.M., Ng K.T.P., Man K. and Poon R.T.P., Overexpression of miR106b promotes metastasis in hepatocellular carcinoma by activating epithelial mesenchymal transition process, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.


Researcher : Patil NG

Project Title:Audit of deaths and complications in surgical patients admitted to university surgical unit
Investigator(s):Patil NG
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:01/1992


Project Title:Risk factors for inguinal hernia in adults: a case-control study
Investigator(s):Patil NG, Lau H
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:Risk factors for hernia development in patients receiving continuous ambulatory peritoneal dialysis (CAPD)
Investigator(s):Patil NG, Lau H
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2003


List of Research Outputs

Chen J.Y., Yip L.M., Lam C.L.K. and Patil N.G., Does medical student willingness to practice peer physical examination translate into action? , In: Ronald Harden, Medical Teacher. 2011, 33: e528-e540.
Patil N.G., Chief Editor, Making Sense in Communication. Hong Kong, IMHSE Publication, Li Ka Shing Faculty of Medicine, HKU, 2012.
Patil N.G., Honorary Director, Department of Education, The College of Surgeons of Hong Kong. 2011.


Researcher : Peng J

List of Research Outputs

Peng J., Chan K.Y., Chen Y., Lamb J.R., Tam P.K.H. and El-Nezamy H.S., Effects of water uptake on melamine renal stone formation in mice, Nephrol Dial Transplant . 2012, 27: 2225-2231.
Peng J., Li D., Chan Y.K., Chen Y., Lamb J.R., Tam P.K.H. and El-Nezamy H.S., Effects of water uptake on melamine renal stone formation in mice, Nephrology Dialysis Transplantation. 2012, 27: 2225-2231.


Researcher : Poon JTC

List of Research Outputs

Li W.Y., Lam W.W.T., Au A.H.Y., Ye M., Law W.L., Poon J.T.C., Kwong A., Suen D.T.K., Tsang J.Y.S., Girgis A. and Fielding R., Interpreting differences in patterns of supportive care needs between patients with breast cancer and patients with colorectal cancer, Psychooncology. 2012, Epub ahead of print.
Poon J.T.C., Law W.L., Chow L.C., Fan J.K.M. and Lo O.S.H., Outcome of laparoscopic resection for colorectal cancer in patients with high operative risk, Annals of Surgical Oncology. 2011, 18(7): 1884-1890.
Szeto G.P.Y., Cheng S.W.K., Poon J.T.C., Ting A.C.W., Tsang R.C.C. and Ho P., Surgeons' static posture and movement repetitions in open and laparoscopic surgery, Journal of Surgical Research. 2012, 172(1): e19-e31.
Wong K.H., Lam C.L.K., Law W.L., Poon J.T.C., Chan P., Kwong D.L.W. and Tsang J.W.H., Validity and reliability study on traditional Chinese FACT-C in Chinese patients with colorectal neoplasm., Journal of Evaluation in Clinical Practice. 2011.


Researcher : Poon RTP

Project Title:American Association for Cancer Research 96th Annual Meeting Blockade of Vascular Endothelial Growth Factor (VEGF) Receptor Enhances the Therapeutic Efficacy of Hypoxia and Chemotherapy in Hepatocellular Carcinoma
Investigator(s):Poon RTP
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2005


Project Title:Training courses on radiofrequency ablation for liver cancers
Investigator(s):Poon RTP, Fan ST, Lam CM, Tso WK
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2006


Project Title:Prospective randomized trial of radiofrequency ablation combined with transarterial chemoembolization versus radiofrequency ablation alone for unresectable hepatocellular carcinoma
Investigator(s):Poon RTP
Department:Surgery
Source(s) of Funding:Hospital Authority - General Award
Start Date:01/2007


Project Title:Outstanding Researcher Award 2006-2007
Investigator(s):Poon RTP
Department:Surgery
Source(s) of Funding:Outstanding Researcher Award
Start Date:11/2007


Project Title:Enhancement of therapeutic efficacy of hypoxia and chemotherapy in hepatocellular carcinoma by blockade of Chemokine (C-X-C motif) receptor 4 (CXCR4)
Investigator(s):Poon RTP, Yang Z
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2008


Project Title:Study of hypoxia-induced recruitment of bone marrow-derived endothelial progenitor cells (EPCs) in tumor angiogenesis of hepatocellular carcinoma (HCC)
Investigator(s):Poon RTP, Yang Z
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2008
Completion Date:11/2011


Project Title:The significance of microRNAs in regulating the metastatic phenotype of CD26+ Cancer Stem Cells in Colorectal Liver Metastasis.
Investigator(s):Poon RTP, Pang RWC
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Chan A.C.Y., Poon R.T.P., Cheung T.T., Chok K.S.H., Chan S.C., Fan S.T. and Lo C.M., Survival analysis of re-resection versus radiofrequency ablation for intrahepatic recurrence after hepatectomy for hepatocellular carcinoma, World Journal of Surgery. 2011, Epub on 2011-10-27.
Chan S.C., Fan S.T., Chok K.S.H., Cheung T.T., Chan A.C.Y., Fung J.Y.Y., Poon R.T.P. and Lo C.M., Survival advantage of primary liver transplantation for hepatocellular carcinoma within the up-to-7 criteria with microvascular invasion, Hepatology International. 2011, Epub on 2011-10-21.
Chan W.M., Lau L.S., Kwok K.M., Law W.L., Ho J.C.M., Chu K.M. and Poon R.T.P., A randomized, double-blind, placebo-controlled, ascending dose infusion trial of the pharmacokinetics of recombinant human Gelsolin in patients with decreased natural Gelsolin levels, American Thoracic Society International Conference, Denver, U.S.A., 13 - 18 May 2011. American Journal of Respiratory and Critical Care Medicine. 2011, 183: A5601.
Chan Y.K., Wong C.M., Kwan S.H., Lee M.F., Cheung K.W., Yuen R.M.F., Lai C.L., Poon R.T.P., Sham P.C. and Ng I.O.L., Genome-wide association study of hepatocellular carcinoma in Southern Chinese patients with chronic hepatitis B virus infection, PLoS One. 2011, 6(12): e28798.
Chen P.J., Curtis C.M., Murphy P.S., Suttle A.B., Gauvin J., Arumugham T., Hodge J.P., Dar M.M. and Poon R.T.P., Phase I dose-finding study of pazopanib in hepatocellular carcinoma: evaluation of early efficacy, pharmacokinetics, and pharmacodynamics, Best Original Paper Award 2011, Department of Surgery, The University of Hong Kong, Clinical Cancer Research. 2011, 17(21): 6914-6923.
Cheung T.T., Poon R.T.P., Yau T.C.C., Tsang D.S., Lo C.M. and Fan S.T., High-intensity focused ultrasound as a treatment for colorectal liver metastasis in difficult position (Letter to the Editor), International Journal of Colorectal Disease. 2011, Epub on 2011-08-13.
Cheung T.T., Chan S.C., Chok K.S.H., Chan A.C.Y., Yu W.C., Poon R.T.P., Lo C.M. and Fan S.T., Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma, Hepatobiliary & Pancreatic Diseases International. 2012, 11(3): 267-271.
Cheung T.T., Chu F.S., Jenkins C.R., Tsang D.S., Chok K.S.H., Chan A.C.Y., Yau T.C.C., Chan S.C., Poon R.T.P., Lo C.M. and Fan S.T., Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma, World Journal of Surgery. 2012, Epub on 2012-06-15.
Chew V., Chen J., Lee D., Loh E., Lee J., Lim K.H., Weber A., Slankamenac K., Poon R.T.P., Yang H., Ooi L.L., Toh H.C., Heikenwalder M., Ng I.O.L., Nardin A. and Abastado J.P., Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma, Gut. 2011, 61(3): 427-438.
Chie W.C., Blazeby J.M., Hsiao C.F., Chiu H.C., Poon R.T.P. and Mikoshiba N., International cross-cultural field validation of an EORTC questionnaire module for patients with primary liver cancer, the EORTC QLQ-HCC18, Hepatology. 2011, Epub on 2011-11-22.
Chie W.C., Blazeby J.M., Hsiao C.F., Chiu H.C. and Poon R.T.P., International cross-cultural field validation of an European Organization for Research and Treatment of Cancer questionnaire module for patients with primary liver cancer, the European Organization for Research and Treatment of Cancer quality-of-life questionnaire HCC18, Hepatology. 2012, 55(4): 1122-1129.
Chiu J., Tang Y.F., Yao T.J., Wong A., Wong H., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Fan S.T., Poon R.T.P. and Yau T.C.C., The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: A retrospective analysis of efficacy, safety, and survival benefits, Cancer. 2012, Epub on 2012-04-19.
Chiu J.W., Pang R.W.C., Poon R.T.P. and Yau T.C.C., Systemic management of advanced hepatocellular carcinoma patients: the role of multi-targeted anti-angiogenic inhibitors, In: Lau J.W.Y. (ed.), Hepatocellular Carcinoma - Clinical Research. Shanghai, InTech, 2011, 309-320.
Chok K.S.H., Chan S.C., Poon R.T.P., Fan S.T. and Lo C.M., Re-resection for metachronous primary hepatocellular carcinoma: is it justified?, ANZ Journal of Surgery. 2012, 82(1-2): 63-67.
Cohen M.J., Levy I., Barak O., Bloom A.I., Fernández Ruiz M., Di Maio M., Perrone F., Poon R.T.P., Shouval D., Yau T.C.C. and Shibolet O., Trans-arterial chemo-embolization (TACE) is safe and efficient for elderly patients with advanced hepatocellular carcinoma (HCC): Results from an international meta-database, Journal of Hepatology. 2012, 54 (Suppl 1): not known.
Dai W.C., Fan S.T., Cheung T.T., Chok K.S.H., Chan A.C.Y., Tsang S.H.Y., Poon R.T.P. and Lo C.M., The impact of family history of hepatocellular carcinoma on its patients' survival, Hepatobiliary & Pancreatic Diseases International. 2012, 11(2): 160-164.
Fan S.T., Yau T.C.C. and Poon R.T.P., Comprehensive management of hepatocellular carcinoma, Chinese Journal of Digestive Surgery. 2011, 10(4): 241-246.
Fan S.T., Yau T.C.C. and Poon R.T.P., 肝癌的綜合治療, 中華消化外科雜誌, 2011, 10: 241-246.
Fatima S., Lee N.P.Y., Tsang F.H., Kolligs F.T., Ng I.O.L., Poon R.T.P., Fan S.T. and Luk J.M.C., Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway by influencing β-catenin in hepatocellular carcinoma, Oncogene. 2012, Epub on 2012-01-16.
Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Han K.H., Kudo M., Ye S.L., Choi J.Y. and Poon R.T.P., Asian consensus workshop report: expert consensus guideline for the management of intermediate and advanced hepatocellular carcinoma in Asia, Oncology. 2011, 81(Suppl 1): 158-164.
Hao K., Lamb J., Zhang C., Xie T., Wang K., Zhang B., Chudin E., Lee N.P.Y., Mao M., Zhong H., Greenawalt D., Ferguson M.D., Ng I.O.L., Sham P.C., Poon R.T.P., Molony C., Schadt E.E., Dai H. and Luk J.M.C., Clinicopathologic and gene expression parameters predict liver cancer prognosis, BMC Cancer. 2011, 11(1): 481.
Ivanovska I., Zhang C., Liu A.M.L., Wong K.F., Lee N.P.Y., Lewis P., Philippar U., Bansal D., Buser C., Scott M., Mao M., Poon R.T.P., Fan S.T., Cleary M.A., Luk J.M.C. and Dai H., Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma, PLoS One. 2011, 6(9): e24582.
Lam C.T., Yang Z., Ng N.P., Wan T.M.H., Lau J.C.S., Ho D.W.Y., Fan S.T. and Poon R.T.P., The potential role of CD44 in liver regeneration, The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.
Lamb J.R., Zhang C., Xie T., Wang K., Zhang B., Hao K., Chudin E., Fraser H.B., Millstein J., Ferguson M., Suver C., Ivanovska I., Scott M., Poon R.T.P., Fan S.T., Yeung C., Lee N.P.Y. and Luk J.M.C., Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting, PLoS One. 2011, 6(7): e20090.
Liu A.M.L., Yao T., Wang W., Wong K.F., Lee N.P.Y., Fan S.T., Poon R.T.P., Gao C. and Luk J.M.C., Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study, BMJ Open. 2012, 2(2): e000825.
Lo C.L.R., Ng I.O.L. and Poon R.T.P., Assessment of the 7th AJCC staging system in prognostic stratification of resected hepatocellular carcinoma, APASL 2012.
Luk J.M.C., Burchard J., Zhang C., Liu A.M.L., Wong K.F., Shek H.P., Lee N.P.Y., Fan S.T., Poon R.T.P., Ivanovska I., Philippar U., Cleary M.A., Buser C.A., Shaw P.M., Lee C.N., Tenen D.G., Dai H. and Mao M., DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival, Journal of Biological Chemistry. 2011, 286(35): 30706-30713.
Majno P., Lencioni R., Mornex F., Girard N., Poon R.T.P. and Cherqui D., Is the treatment of hepatocellular carcinoma on the waiting list necessary?, Liver Transplantation. 2011, 17(Suppl 2): S98-S108.
Ng K.T.P., Guo D., Cheng Q., Geng W., Ling C., Li C., Liu X., Ma Y.Y., Lo C.M., Poon R.T.P., Fan S.T. and Man K., A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma, PLoS One. 2012, 7(2): e31655.
Poon R.T.P., Chan P., Tai K.S., Cheung T.T., Chan A.C.Y., Kowk P.C., Jin K., Lee K.F. and Lap P.B., A multi-center phase II trial of Bevacizumab (B) pre- and post-transarterial chemoembolization (TACE) treatment for patients with localized rnresectable HCC: interim safety analyses, Best Abstract Award, Round Asia Oncology Forum, Chinese Society of Clinical Oncology, Shanghai, China . 2011.
Poon R.T.P., Advances in nonsurgical HCC treatments in Asia (Invited Lecture), Chinese American Hematologist and Oncologist Network Annual Meeting, Chicago, USA, 3 June 2012. 2012.
Poon R.T.P., Asian experience with drug-eluting beads for HCC (Invited Lecture), International Liver Cancer Association Annual Meeting, Hong Kong, 3-4 September 2011. 2011.
Poon R.T.P., Associate Director (March 2005 – now), Continuous Medical Education Office, Hong Kong Academy of Medicine. 2011.
Poon R.T.P., Associate Editor (2006 – now), HBP Surgery. 2011.
Poon R.T.P., Associate Editor (2008 – now), World Journal of Surgery. 2011.
Poon R.T.P., Associate Editor (July 2003 – now), Cancer Reviews: Asia-Pacific. 2011.
Poon R.T.P., Biomarkers for HCC prognosis and therapy (Invited Lecture), Asian-Pacific Association for Hepato-Pancreato-Biliary Association Biennial Meeting, Melbourne, Australia, 26-28 September 2011. 2011.
Poon R.T.P., Chairman (2011 - now), Hong Kong Liver Cancer Foundation. 2012.
Poon R.T.P., Chairman of Advisory Board (2009 - now), Asian Foundation of Cancer Research. 2011.
Poon R.T.P., Committee Member (2003 - now), Research Support for Higher Surgical Trainees Committee, The College of Surgeons of Hong Kong. 2011.
Poon R.T.P., Committee member (2006 - now), Central Committee on Liver Diseases, Hospital Authority, Hong Kong. 2011.
Poon R.T.P., Council Member (2011 - now), Hong Kong Society of Hepatobiliary and Pancreatic Surgery. 2012.
Poon R.T.P., Curative therapy for early HCC (Invited Lecture), Asia-Pacific Association for Study of Liver Annual Conference, Taipei, Taiwan, 16-18 February 2012. 2012.
Poon R.T.P., Current unmet needs and evolving landscape in advanced HCC (Invited Lecture), World Congress of Gastrointestinal Cancer – Asia Pacific Perspectives, Seoul, Korea, 28 August 2011. 2011.
Poon R.T.P., Deputy Chairman (2003 – now), Institutional Review Board of West Cluster Hospitals and the University of Hong Kong. 2011.
Poon R.T.P., Editor (November 2002 – now), Digestive Surgery (Chinese). 2011.
Poon R.T.P., Editorial Board Member (2007 – now), Annals of Surgical Oncology. 2011.
Poon R.T.P., Editorial Board Member (2007 – now), Journal of Gastrointestinal Surgery. 2011.
Poon R.T.P., Editorial Board Member (2008 – now), Journal of Gastroenterology and Hepatology. 2011.
Poon R.T.P., Editorial Board Member (2008 – now), World Journal of Gastroenterology. 2011.
Poon R.T.P., Editorial Board Member (2009 – now), Oncology Tribune. 2011.
Poon R.T.P., Editorial Board member (March 2003 – now), Cancer Therapy. 2011.
Poon R.T.P., Executive Council Member and Chairman of Scientific Committee (2010 - 2012), International Hepato-Pancreato-Biliary Association. 2012.
Poon R.T.P., Governing Council Member (2010 - 2012), International Liver Cancer Association. 2012.
Poon R.T.P., Honorary Advisor (December 1999 – now), Continuing Medical Education Programme, The Association of Licentiates of Medical Council of Hong Kong. 2011.
Poon R.T.P., Honorary Fellow (2005 - present), National Chapter of European Hepatobiliary-Pancreatic Association, Republic of Serbia and Montenegro. 2012.
Poon R.T.P., Instructor (1998 - now), Advanced Trauma Life Support Course, American College of Surgeons. 2011.
Poon R.T.P., International Advisory Committee Member (2011 - now), Cancer Research Institute, Seoul National University, Korea. 2012.
Poon R.T.P., Live donor liver transplantation (Invited Lecture), Symposium on Advance Approach to Common Gastrointestinal and Hepatic Diseases, Bangkok, Thailand, 4-5 August 2011. 2011.
Poon R.T.P. and Borys N., Lyso-thermosensitive liposomal doxorubicin: an adjuvant to increase the cure rate of radiofrequency ablation in liver cancer, Future Oncology. 2011, 7(8): 937-945.
Poon R.T.P., Molecular targets for therapy in HCC (Invited Lecture), Symposium of State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong, 24 September 2011. 2011.
Poon R.T.P., Natural history and treatment options for HCC (Invited Lecture), Hong Kong Society of Nuclear Medicine Scientific Meeting, Hong Kong, 11 March 2012. 2012.
Poon R.T.P., Postoperative care after hepatic resection (Invited Lecture), Asian-Pacific Association for Hepato-Pancreato-Biliary Association Biennial Meeting, Melbourne, Australia, 26-28 September 2011. 2011.
Poon R.T.P., Prevention of recurrence after resection of hepatocellular carcinoma: a daunting challenge (Editorial), Hepatology. 2011, 54(3): 757-759.
Poon R.T.P., Recent advances in surgical and non-surgical management of HCC (Invited Lecture), Annual HBP Meeting, Imperial College, London, UK, 17 October 2011. 2011.
Poon R.T.P., Research Committee Member (2005 - now), The College of Surgeons of Hong Kong. 2011.
Poon R.T.P., Resection or ablation for early HCC (Invited Lecture), International Liver Cancer Association Annual Meeting, Hong Kong, 3-4 September 2011. 2011.
Poon R.T.P., Surgical and non-surgical management of HCC – Hong Kong experience (Invited Lecture), Symposium on Advance Approach to Common Gastrointestinal and Hepatic Diseases, Bangkok, Thailand, 4-5 August 2011. 2011.
Poon R.T.P., Surgical management of HCC in Asia (Invited Lecture), The 2nd Asia-Pacific Primary Liver Cancer Expert Meeting, Osaka,Japan, 1-3 July 2011. 2011.
Poon R.T.P., Therapeutic advances in HCC: emerging clinical trial results in unresectable disease (Invited Lecture), Asia-Pacific Association for Study of Liver Annual Conference, Taipei, Taiwan, 16-18 February 2012. 2012.
Poon R.T.P., Thermosensitive liposomes in combination with thermal ablation (Invited Lecture), The 3rd European Conference on Interventional Oncology, Florence, Italy, 25-28 April 2012. 2012.
Poon R.T.P., Transplantation or resection for early HCC (Invited Lecture), The 2nd Asia-Pacific Primary Liver Cancer Expert Meeting, Osaka, Japan, 1-3 July 2011. 2011.
Poon R.T.P., mTOR pathway in HCC (Invited Lecture), Regional Investigator Meeting of EVOLVE-1 HCC Study, Novartis, Taipei, Taiwan, 1 September 2011. 2011.
Sung W.K., Zheng H., Li S., Chen R., Liu X., Li Y., Lee N.P.Y., Lee W.H., Wong K.F., Liu A.M.L., Poon R.T.P., Fan S.T., Chan K.L. and Luk J.M.C., Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma, Nature Genetics. 2012, 44(7): 765-769.
Tung K.K., Mak K.M., Fatima S., Lo C.L.R., Zhao H., Zhang C., Dai H., Poon R.T.P., Yuen R.M.F., Lai C.L., Li J.J., Luk J.M.C. and Ng I.O.L., Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma, Liver International. 2011, 31(10): 1494-1504.
Wang X., Zhang W., Lui E.L.H., Zhu Y., Lu P., Yu X., Sun J., Yang S., Poon R.T.P. and Fan S.T., Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma, International Journal of Cancer. 2011, 131(3): E163-172.
Wong D.K.H., Huang F.Y., Lai C.L., Poon R.T.P., Seto W.K.W., Fung J.Y.Y., Hung I.F.N. and Yuen R.M.F., Occult hepatitis B infection and HBV replicative activity in patients with cryptogenic cause of hepatocellular carcinoma, Hepatology. 2011, 54(3): 829-836.
Wong D.K.H., Huang F.Y., Lai C.L., Poon R.T.P., Seto W.K.W., Fung J.Y.Y., Hung I.F.N. and Yuen R.M.F., Occult hepatitis B infection and HBV replicative activity in patients with cryptogenic cause of hepatocellular carcinoma, Hepatology. 2011, 54(3): 829-36.
Wong H., Tang Y.F., Yao T., Chiu J., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Poon R.T.P., Fan S.T. and Yau T.C.C., The outcomes and safety of single-agent sorafenib in the treatment of elderly patients with advanced hepatocellular carcinoma (HCC), Oncologist. 2011, 16(12): 1721-1728.
Wood B.J., Poon R.T.P., Locklin J.K., Dreher M.R., Ng K.K.C. and Eugeni M., Phase I study of heat-deployed liposomal doxorubicin during radiofrequency ablation for hepatic malignancies, Journal of Vascular and Interventional Radiology. 2011, Epub on 2011-12-16.
Yau T.C.C., Cheng P.N., Chan P., Chan W.Y.L., Chen L., Yuen J., Pang R.W.C., Fan S.T. and Poon R.T.P., A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma, Investigational New Drugs. 2012, Epub on 2012-03-17.
Yau T.C.C., Sukeepaisarnjaroen W., Chao Y., Yen C.J., Lausoontornsiri W., Chen P.J., Sanpajit T., Lencioni R., Camp A., Kallender H., Ottesen L.H. and Poon R.T.P., A phase I/II study of Foretinib, an oral multikinase inhibitor targeting MET, RON, AXL, TIE-2 and VEGFR in advanced hepatocellular carcinoma (HCC), Journal of Clinical Oncology. 2011, 29(Suppl): abstr 4082.
Yau T.C.C., Chen P.J., Chan P., Curtis C.M., Murphy P.S., Suttle A.B., Gauvin J., Hodge J.P., Dar M.M. and Poon R.T.P., Phase I dose-finding study of pazopanib in hepatocellular carcinoma: evaluation of early efficacy, pharmacokinetics, and pharmacodynamics, Clinical Cancer Research. 2011, 17(21): 6914-6923.
Yau T.C.C., Wong H., Chan P., Yao T., Pang R.W.C., Cheung T.T., Fan S.T. and Poon R.T.P., Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease, Investigational New Drugs. 2012, Epub on 2012-03-09.
Yau T.C.C., Yao T.J., Chan P., Wong H., Pang R.W.C., Fan S.T. and Poon R.T.P., The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib, Oncologist. 2011, Epub on 2011-09-01.
Yau W.L., Pang R.W.C., Lee K.W., Lam C.S.C., Wo Y.H., Ng L., Chan J.Y.K., Chow A.K.M., Ng K.T.P., Man K. and Poon R.T.P., Overexpression of miR106b promotes metastasis in hepatocellular carcinoma by activating epithelial mesenchymal transition process, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Poon TCJ

List of Research Outputs

Law W.L., Poon T.C.J., Fan J.K.M. and Lo O.S.H., Survival following laparoscopic versus open resection for colorectal cancer, International Journal of Colorectal Disease. 2012, Epub ahead of print.
Poon T.C.J., Cheung C.W., Law W.L., Fan J.K.M. and Lo O.S.H., A randomized controlled trial comparing the outcomes of patients who undergo single port laparoscopic colectomy and conventional laparoscopic colectomy, SAGES 2012, San Diego, California. 7-10 March . 2012.
Poon T.C.J., Cheung C.W., Fan J.K.M., Lo O.S.H. and Law W.L., Single incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized controlled trial, The Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting 2012, San Diego, California, U.S.A., 7 - 10 March 2012.
Poon T.C.J., Cheung C.W., Fan J.K.M., Lo O.S.H. and Law W.L., Single-incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized, controlled trial, Surgical endoscopy. 2012, Epub ahead of print.
Quereshy F.A., Poon T.C.J. and Law W.L., Long-term outcomes of stenting as a bridge to surgery for acute left-sided malignant colonic obstruction, American Society of Clinical Oncology Annual Meeting 2012, Chicage, Illinois, U.S.A., 1 - 5 June 2012.
She W.H., Poon T.C.J., Fan J.K.M., Lo O.S.H. and Law W.L., Stoma reversal in patients who underwent low anterior resection and diversion stoma for rectal cancer, Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Wong C.K.H., Lam C.L.K., Poon T.C.J., McGhee S., Law W.L., Kwong D.L.W., Tsang J.W.H. and Chan P., Direct medical costs of care for Chinese patients with colorectal neoplasia: a health care service provider perspective, Journal of Evaluation in Clinical Practice. Blackwell Publishing, 2011, 18: 1186-1195.
Wong C.K.H., Lam C.L.K., Rowen D., McGhee S., Ma K.P., Law W.L., Poon T.C.J., Chan P., Kwong D.L.W. and Tsang J.W.H., Mapping the functional assessment of cancer therapy-general or -colorectal to SF-6D in Chinese patients with colorectal neoplasm, Value in Health. Elsevier, 2012, 15(3): 495-503.
Wong C.K.H., Lam C.L.K., McGhee S., Law W.L., Poon T.C.J., Chan P., Kwong D.L.W., Tsang J.W.H., Rowen D.L. and Brazier J., Mapping the functional assessment of cancer therapy-general or -colorectal to preference-based values measured by SF-6D in patients with colorectal neoplasm, 18th Annual Conference of the International Society for Quality of Life Research, Denver, Colorado, USA, 28 October 2011.
Wong K.P., Poon T.C.J., Fan J.K.M. and Law W.L., Prognostic value of lymph node ratio in stage III colorectal disease, Colorectal Disease. 2011, 13(10): 1116-1122.


Researcher : Pu JKS

List of Research Outputs

Chong B.H., Lau K.K., Chan K.H., Lui W.M., Leung G.K.K., Lau C.P., Tse H.F., Pu J.K.S. and Siu C.W., Use of aspirin in Chinese after recovery from primary intracranial haemorrhage, Thrombosis and Haemostasis. 2012, 107(2): 241-247.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in human malignant gliomas: a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide, The Society for NeuroOncology. 2011.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in malignant gliomas - a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide (P4HB) (Abstract), Neuro-oncology. 2011, 13(3): 111.
Leung G.K.K., Sun S., Lee D., Lee N.P. and Pu J.K.S., Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide, The 9th Meeting of the Asian Society of Neuro-oncology, Taipei, Taiwan, 20 - 22 April 2012.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Identifying molecular candidates associated with acquired temozolomide resistance in human malignant glioma - a proteomics approach., The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Leung G.K.K., Ho J.C.Y. and Pu J.K.S., Pituitary enlargement in spontaneous intracranial hypotension - a diagnostic pitfall, Acta Neurochirurgica(Wien). 2011, 153(12): 2445-2446.
Pong V., Chan K.H., Chong B.H., Lui W.M., Leung G.K.K., Tse H.F., Pu J.K.S. and Siu D.C.W., Long-term outcome and prognostic factors after spontaneous cerebellar hemorrhage. , Cerebellum. 2012.
Pu J.K.S., Chan R.T.T., Ng G.K.B., Leung G.K.K., Hung K.N. and Fung C.F., Using bevacizumab in the fight against malignant glioma: first results in Asian patients, Hong Kong Medical Journal. 2011, 17(4): 274-279.
Sun S., Pu J.K.S., Leung G.K.K. and Wong S.T.S., Prolyl 4-hydroxylase, Beta polypeptide (P4HB) as a Potential Target for Combating Temozolomide Resistance in Human Malignant Glioma, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Sun S., Wong S.T.S., Zhang X., Pu J.K.S., Lee N.P.Y., Day P.J., Ng K.B., Lui W.M. and Leung G.K.K., Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines , Journal of Neuro-oncology. 2012, 107(1): 89-100.
Zhang X., Sun S., Pu J.K.S., Tsang C.O.A., Lee D., Lui W.M., Wong S.T.S., Leung G.K.K. and Man V.O.Y., Long non-coding RNA expression profiles predict clinical phenotypes in glioma, Neurobiology of Disease. 2012, 48(1): 1-8.


Researcher : Qing K

List of Research Outputs

Cheng S.W.K., Qing K. and Yiu W.K., A morphologic study of chronic type B aortic dissections and aneurysms after thoracic endovascular stent grafting, The 26th Annual Meeting of the Western Vascular Society, Kauai, Hawaii, 17-20 September 2011.
Qing K., Yiu W.K. and Cheng S.W.K., A morphologic study of chronic type B aortic dissections and aneurysms after thoracic endovascular stent grafting, Journal of Vascular Surgery. 2012, 55(5): 1268-1276.


Researcher : Qu Z

List of Research Outputs

Qu Z., Cheuk L.Y. and Cheng S.W.K., Differential expression of sphingosine-1-phosphate receptors in abdominal aortic aneurysms, Mediators of Inflammation. 2012, 2012: 643609.
Qu Z., Expression of sphingosine-1-phosphate receptor in abdominal aortic aneurysm, Dissertation, Master of Philosophy, The University of Hong Kong. 2011.


Researcher : Ren Y

Project Title:XL VIII Annual International Conference of the British Association of Paediatric Surgeons Macrophage Migration Inhibitory Factor in Necrotizing Enterocolitis
Investigator(s):Ren Y
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2001


Project Title:Proteomics computational analysis of Severe Acute Respiratory Syndrome
Investigator(s):Ren Y, Tam PKH, Peiris JSM, He Q
Department:Surgery
Source(s) of Funding:VCO SARS Research Fund
Start Date:07/2003




Researcher : Sat EWY

List of Research Outputs

Ngan E.S.W., Garcia-Barcelo M.M., Yip B.H.K., Poon P.C., Lau C.S.T., Kwok K.M., Sat E.W.Y., Sham M.H., Wong K.K.Y., Wainwright B.J., Cherny S.S., Hui C.C., Sham P.C., Lui V.C.H. and Tam P.K.H., Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung’s disease in mice and humans, Journal of Clinical Investigation. 2011, 121(9): 3467-3478.


Researcher : Shao Y

Project Title:Exploitation of the interplay between aldose reductase and cytokine network during hepatic ischemia reperfusion injury
Investigator(s):Shao Y, Li C, Man K, Lo CM
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2011
Completion Date:06/2012


Project Title:IMMUNOLOGY 2012™ 2012 conference The role of regulatory B cells during the progression of human hepatocellular carcinoma
Investigator(s):Shao Y
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2012


List of Research Outputs

Li C., Shao Y., Ng K.T.P., Liu X., Ling C., Ma Y.Y., Geng W., Fan S.T., Lo C.M. and Man K., FTY720 suppresses liver tumor metastasis by reducing the population of circulating endothelial progenitor cells, PLoS One. 2012, 7(2): e32380.
Man K., Shao Y., Li C., Ling C., Geng W., Ma Y.Y., Ng K.T.P., Fan S.T. and Lo C.M., Acute phase liver graft injury mobilizes regulating B cells after LDLT for HCC patients through TLR4/CXCL10/CXCR3 signaling, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.
Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.


Researcher : Sharr WW

List of Research Outputs

Chan S.C., Lo C.M., Chok K.S.H., Sharr W.W., Cheung T.T., Tsang S.H.Y., Chan A.C.Y. and Fan S.T., Modulation of graft vascular inflow guided by flowmetry and manometry in liver transplantation, Hepatobiliary & Pancreatic Diseases International. 2011, 10(6): 649-656.
Chok K.S.H., Fung J.Y.Y., Chan S.C., Cheung T.T., Sharr W.W., Chan A.C.Y., Fan S.T. and Lo C.M., Outcomes of living donor liver transplantation for patients with preoperative type 1 hepatorenal syndrome and acute hepatic decompensation, Liver Transplantation. 2012, Epub on 2012-01-30.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Fung J.Y.Y., Tsang S.H.Y., Fan S.T. and Lo C.M., Single-centre experience of liver transplantation for familial amyloidotic polyneuropathy of non-Val30Met variants in Chinese patients, Amyloid. 2012, 19(1): 33-36.
Fung J.Y.Y., Chan S.C., Cheung C.K.Y., Chok K.S.H., Sharr W.W., Chan A.C.Y., Dai W.C., Cheung T.T., Fan S.T., Lai C.L., Yuen R.M.F. and Lo C.M., Entecavir Versus Lamivudine Prophylaxis without Hepatitis B Immune Globulin after Liver Transplantation for Chronic Hepatitis B., 18th Annual International Congress on ILTS Location: San Francisco, USA. May 16-19, 2012. Liver Transplantation.. 2012, 18 (supp 1): S124.
Fung J.Y.Y., Cheung C.K.Y., Chan S.C., Yuen R.M.F., Chok K.S.H., Sharr W.W., Dai W.C., Chan A.C.Y., Cheung T.T., Tsang S.H.Y., Lam B.K.Y., Lai C.L. and Lo C.M., Entecavir monotherapy is effective in suppressing hepatitis B virus after liver transplantation, Gastroenterology. 2011, 141(4): 1212-1219.
Fung J.Y.Y., Chan S.C., Yuen R.M.F., Lai C.L., Chok K.S.H., Sharr W.W., Dai W.C., Fan S.T. and Lo C.M., Long-term Outcome of Lamivudine Mono-prophylaxis After Liver Transplantation In Hepatitis B Patients , 62nd Annual Meeting Of The American-association-for-the-study-of-liver-diseases (AASLD) Location: San Francisco, USA. November 04-08, 2011. Hepatology . 2011, 54(Supp 1): 450A-450A.


Researcher : Shek HP

List of Research Outputs

Luk J.M.C., Burchard J., Zhang C., Liu A.M.L., Wong K.F., Shek H.P., Lee N.P.Y., Fan S.T., Poon R.T.P., Ivanovska I., Philippar U., Cleary M.A., Buser C.A., Shaw P.M., Lee C.N., Tenen D.G., Dai H. and Mao M., DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival, Journal of Biological Chemistry. 2011, 286(35): 30706-30713.
Shek H.P., Luk J.M.C. and Lee N.P.Y., Targeting serine peptidase inhibitor, Kazal type 1 (SPINK1) as a potential treatment for hepatocellular carcinoma (Poster and Abstract), The 5th Annual Conference of the International Liver Cancer Association, Hong Kong, 2-4 September 2011.
Shek H.P. and Lee N.P.Y., Tumorigenic properties of serine peptidase inhibitor, Kazal type 1 (SPINK1) in hepatocellular carcinoma (Poster & Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.


Researcher : Shek HP

List of Research Outputs

Luk J.M.C., Burchard J., Zhang C., Liu A.M.L., Wong K.F., Shek H.P., Lee N.P.Y., Fan S.T., Poon R.T.P., Ivanovska I., Philippar U., Cleary M.A., Buser C.A., Shaw P.M., Lee C.N., Tenen D.G., Dai H. and Mao M., DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival, Journal of Biological Chemistry. 2011, 286(35): 30706-30713.
Shek H.P., Luk J.M.C. and Lee N.P.Y., Targeting serine peptidase inhibitor, Kazal type 1 (SPINK1) as a potential treatment for hepatocellular carcinoma (Poster and Abstract), The 5th Annual Conference of the International Liver Cancer Association, Hong Kong, 2-4 September 2011.
Shek H.P. and Lee N.P.Y., Tumorigenic properties of serine peptidase inhibitor, Kazal type 1 (SPINK1) in hepatocellular carcinoma (Poster & Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.


Researcher : Shin VY

Project Title:Role of EP2 receptor in the sensitization of platinum-based anticancer drug in gastric cancer
Investigator(s):Shin VY, Chu KM
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:06/2012


List of Research Outputs

Ng E.K.O., Leung P.H.C., Shin V.Y., Wong L.P., Ma E.S.K., Jin H.C., Chu K.M. and Kwong A., Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients, PLoS One. 2011, 6(7): e22233.


Researcher : Sihoe ADL

List of Research Outputs

Chan W.Y., Kang S.R., Yen H., Li C.L., Tang L.L.S., Yu C.L., Yuen K.M., Chan W.W., Wong D.D.Y., Lai W.W.K., Kwong D.L.W., Sihoe A.D.L., Poon L.L.M., Guan Y., Nicholls J.M., Peiris J.S.M. and Chan M.C.W., Tissue tropism of swine influenza viruses and reassortants in ex vivo cultures of the human respiratory tract and conjunctiva., J Virol. 2011, 85(22): 11581-7.
Lam C.L.D., Girard L., Beer D.G., Gerald W.L., Kris M., Sihoe A.D.L., Cheng L.C., Wong M.P., Chung L.P., Ip M.S.M., Lam W.K., Gazdar A.F., Wistuba I.I. and Minna J.D., Expression of LATS2 and STK17B distinguishes epidermal growth factor receptor (EGFR) gene mutations in exons 19 and 21 from those in 18 and 20 in lung adenocarcinomas, World Congress of Lung Cancer 2011.


Researcher : Siriwardana RC

List of Research Outputs

Siriwardana R.C., Chan S.C., Chok K.S.H., Lo C.M. and Fan S.T., Effects of the liver volume and donor steatosis on errors in the estimated standard liver volume, Liver Transplantation. 2011, 17(12): 1437-1442.


Researcher : So MT

List of Research Outputs

Cherny S.S., Garcia-Barcelo M.M., Leon Y.Y., So M.T., Sham P.C. and Tam P.K.H., RET mutational spectrum in Hirschsprungs disease: Evaluation of 601 Chinese patients, 12th International Congress of Human Genetics. 2011, 790.
Leon Y.Y., So M.T., Lui V.C.H., Hofstra R.M.W., Tam P.K.H., Ngan E.S.W. and Garcia-Barcelo M.M., Functional analyses of RET mutations in Chinese Hirschsprung disease patients, Birth Defects Research (Part A): Clinical and Molecular Teratology. 2012, 94(1): 47-51.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.


Researcher : Suen DTK

List of Research Outputs

Au H.Y.A., Lam W.W.T., Tsang J.W.H., Yau T.K., Yau T.K., Soong I., Yeo W., Suen J., Ho W.M., Wong K.Y., Kwong A., Suen D.T.K., Sze W.K., Ng A., Girgis A. and Fielding R., Change patterns in supportive care needs among women diagnosed with advanced breast cancer (abstract), 18th Hong Kong International Cancer Congress, 3-5 November 2011, Hong Kong. Hong Kong, Centre for Cancer Research, University of Hong Kong, 2011, A76.
Au H.Y.A., Lam W.W.T., Tsang J.W.H., Yau T.K., Soong I., Yeo W., Suen J., Ho W.M., Wong K.Y., Kwong A., Suen D.T.K., Sze W.K., Ng A., Girgis A. and Fielding R., Change patterns of supportive care needs among women diagnosed with advanced breast cancer (abstract and powerpoint presentation), 18th Hong Kong International Cancer Congress, 3-5 November 2011, Hong Kong. Hong Kong, Centre for Cancer Research, University of Hong Kong, 2011.
Au H.Y.A., Lam W.W.T., Chan M.C.M., Or A.Y.M., Kwong A., Suen D.T.K., Wong A.L., Juraskova I., Wong W.T.T. and Fielding R., Development and pilot-testing of a decision aid for use among Chinese women facing breast cancer surgery, Health Expectations. 2011, 14(4): 405-416.
Au H.Y.A., Lam W.W.T., Cheung O.K.Y., Tsang J.W.H., Yau T.K., Soong I., Yeo W., Suen J., Ho W.M., Wong K.Y., Kwong A., Suen D.T.K., Sze W.K., Ng A., Girgis A. and Fielding R., Unmet supportive care needs in Hong Kong Chinese women confronting advanced breast cancer (abstract and poster presentations), Psycho-Oncology Supplement: Abstracts for the 13th World Congress of Psycho-Oncology, 16–20 October 2011, Antalya, Turkey. 2011, 20(Suppl 2): 198-199.
Au H.Y.A., Lam W.W.T., Kwong A., Suen D.T.K., Tsang J.W.H., Yeo W., Suen J., Ho W.M., Yau T.K., Soong I., Wong K.Y., Sze W.K., Ng A., Girgis A. and Fielding R., Validation of the Chinese version of the short-form supportive Care Needs Survey Questionnaire (SCNS-SF34-C), Psycho-Oncology. 2011, 20(12): 1292-1300.
Kwong A., Wong C.H., Suen D.T.K., Co M., Kurian A.W., West D.W. and Ford J.M., Accuracy of BRCA1/2 mutation prediction models for different ethnicities and genders: experience in a Southern Chinese Cohort, World Journal of Surgery. 2012, Epub ahead of print.
Li W.Y., Lam W.W.T., Au A.H.Y., Ye M., Law W.L., Poon J.T.C., Kwong A., Suen D.T.K., Tsang J.Y.S., Girgis A. and Fielding R., Interpreting differences in patterns of supportive care needs between patients with breast cancer and patients with colorectal cancer, Psychooncology. 2012, Epub ahead of print.
Li W.Y., Lam W.W.T., Law W.L., Poon J.T.C., Kwong A., Suen D.T.K. and Fielding R., Interpreting patterns in supportive care needs between breast and colorectal cancers (abstract and poster presentations), Psycho-Oncology Supplement: Abstracts for the 13th World Congress of Psycho-Oncology, 16–20 October 2011, Antalya, Turkey. 2011, 20(Suppl 2): 230-231.


Researcher : Suen TKD

List of Research Outputs

Au A.H.Y., Lam W.W.T., Tsang J.W.H., Yau T.K., Soong S.I., Yeo W., Suen J., Ho W.M., Wong K.Y., Kwong A., Suen T.K.D., Sze W.K., Ng A., Girgis A. and Fielding R., Support care needs in Hong Kong Chinese women confronting advanced breast cancer, Psychooncology. 2012.


Researcher : Sun KW

List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.


Researcher : Sun S

Project Title:Identification of therapeutic targets to combat glioblastoma drug resistance by proteomic profiling
Investigator(s):Sun S, Leung GKK
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:07/2010


List of Research Outputs

Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in human malignant gliomas: a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide, The Society for NeuroOncology. 2011.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in malignant gliomas - a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide (P4HB) (Abstract), Neuro-oncology. 2011, 13(3): 111.
Leung G.K.K., Sun S., Lee D., Lee N.P. and Pu J.K.S., Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide, The 9th Meeting of the Asian Society of Neuro-oncology, Taipei, Taiwan, 20 - 22 April 2012.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Identifying molecular candidates associated with acquired temozolomide resistance in human malignant glioma - a proteomics approach., The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Sun S., Pu J.K.S., Leung G.K.K. and Wong S.T.S., Prolyl 4-hydroxylase, Beta polypeptide (P4HB) as a Potential Target for Combating Temozolomide Resistance in Human Malignant Glioma, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Sun S. and Leung G.K.K., Prolyl 4-hydroxylase, beta polypeptide (P4HB): a potential target for overcoming temozolomide resistance in human malignant glioma, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.
Sun S., Wong S.T.S., Zhang X., Pu J.K.S., Lee N.P.Y., Day P.J., Ng K.B., Lui W.M. and Leung G.K.K., Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines , Journal of Neuro-oncology. 2012, 107(1): 89-100.
Sun S. and Leung G.K.K., Proteomic alterations associated with acquired temozolomide resistance in human malignant gliomas: the role of prolyl 4-hydroxylase, beta polypeptide, Round Asia Oncology Forum 2011, Shanghai, China, 27 - 28 August 2011.
Zhang X., Sun S., Pu J.K.S., Tsang C.O.A., Lee D., Lui W.M., Wong S.T.S., Leung G.K.K. and Man V.O.Y., Long non-coding RNA expression profiles predict clinical phenotypes in glioma, Neurobiology of Disease. 2012, 48(1): 1-8.


Researcher : Sung WK

List of Research Outputs

Sung W.K., Zheng H., Li S., Chen R., Liu X., Li Y., Lee N.P.Y., Lee W.H., Wong K.F., Liu A.M.L., Poon R.T.P., Fan S.T., Chan K.L. and Luk J.M.C., Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma, Nature Genetics. 2012, 44(7): 765-769.


Researcher : Tam PC

List of Research Outputs

Ng A.T.L., Fu K.K.F., Wong B.T.H., Ho K.L. and Tam P.C., Simultaneous antegrade and retrograde approach for complex upper tract stones in modified supine valdivia position (Poster), The 31st Congress of the Societe International d’Urologie, Berlin, Germany, 16 - 20 October 2011.
Yip S.K.H., Yee C.H., Ng C.F., Lam N.Y., Ho K.L., Ma W.K., Li C.M., Hou S.M., Tam P.C., Yiu M.K. and Fan C.W., Robot-assisted radical prostatectomy in Hong Kong: a review of 235 cases, Journal of Endourology. 2012, 26(3): 258-263.


Researcher : Tam PKH

Project Title:Establishing a "train-the-trainers" programme for paediatric surgery in China
Investigator(s):Tam PKH, Lin C
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/1998


Project Title:Expanding the "Train-the-Trainers" programme for paediatric surgery in China
Investigator(s):Tam PKH, Lin C
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2000


Project Title:Improving the survival and quality of life of children with cancers in China
Investigator(s):Tam PKH, Wong IHN, Chan GCF, Ren Y, Lin C
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2003


Project Title:The study of co-stimulatory function of sonic hedgehog in CD4+ lymphocytes
Investigator(s):Tam PKH, Chan VSF
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Further expansion of the "Train-the-Trainers" programme for paediatric surgery in China
Investigator(s):Tam PKH, Chan KL, Wong KKY
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:05/2005


Project Title:Offering Iaparoscopic surgical workshops in China
Investigator(s):Tam PKH, Wong KKY, Yip PKF
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2007


Project Title:Offering surgical care to poor children with major congenital anomalies in rural China
Investigator(s):Tam PKH, Wong KKY, Yip PKF
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2008


Project Title:Genome-wide association study for the identification of genes underlying anorectal malformations
Investigator(s):Tam PKH, Cherny SS, Garcia-Barcelo MM, Sham PC
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2008
Completion Date:08/2011


Project Title:Establishing a quaternary peadiatric gastrointestinal centre for Hong Kong
Investigator(s):Tam PKH, Wong KKY, Wong RMS
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:12/2008


Project Title:Improving the surgical care of sick children in Hong Kong by providing cutting edge minimally invasive and robotic surgery
Investigator(s):Tam PKH
Department:V-C's Office
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:03/2009


Project Title:NRG1 intron 1 SNPs in Hirschsprung’s disease
Investigator(s):Tam PKH, Garcia-Barcelo MM
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010
Completion Date:02/2012


Project Title:Establishing S.K. Yee Medical Foundation clinical fellowships
Investigator(s):Tam PKH, Wong KKY
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Deep Re-Sequencing of Hirschsprung's Disease Candidate Genes
Investigator(s):Tam PKH, Cherny SS, Garcia-Barcelo MM, Lok S, Sham PC
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2010


Project Title:Validation of NRG3 copy number variations in the genome of Hirschsprung's patients
Investigator(s):Tam PKH, Garcia-Barcelo MM
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2011


Project Title:BAPS 2011 International Congress Identification of ADD3 as a susceptible gene for biliary atresia: evidence from genetic fine mapping
Investigator(s):Tam PKH
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2011
Completion Date:07/2011


Project Title:Advancing laparoscopic skills in China - an extension of the current laparoscopic workshop scheme
Investigator(s):Tam PKH, Wong KKY
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:03/2012


Project Title:Study of de novo copy number variations (CNV) in Hirschsprung disease
Investigator(s):Tam PKH, Garcia-Barcelo MM
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Chan K.L., Chung H.Y., Chan S.C. and Tam P.K.H., Timely liver transplantation is essential for the survival of paediatric patients with hepatopulmonary syndrome, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Cherny S.S., Garcia-Barcelo M.M., Leon Y.Y., So M.T., Sham P.C. and Tam P.K.H., RET mutational spectrum in Hirschsprungs disease: Evaluation of 601 Chinese patients, 12th International Congress of Human Genetics. 2011, 790.
Chow H.M., Tam P.K.H. and Ngan E.S.W., Neural crest and Hirschsprung’s disease, In: Srivastava R.K. and Shankar S. (eds.), Stem Cell and Human Diseases. New York, Springer, 2011, 353-386.
Chung H.Y., Chan K.L., Chan I.H.Y., Ng I.O.L., Chan G.C.F., Chan S.C. and Tam P.K.H., Clinical experience in managing post transplant lymphoproliferative disease (PTLD) in paediatric patients after liver transplant, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Cui L., Wong E.H.M., Zhu J., Almeida M.F. .D.E., Tam P.K.H. and Garcia-Barcelo M.M., Genetic study of a family segregating Shah-Waardenburg syndrome, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
Garcia-Barcelo M.M., Tam P.K.H., Cherny S.S. and Sham P.C., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, The 61st Annual Meeting of the American Society of Human Genetics, Montreal, Canada, 11 - 15 October 2011.
Garcia-Barcelo M.M. and Tam P.K.H., Identification of ADD3 as a susceptible gene for biliary atresia: evidence from genetic fine mapping (Oral presentation), The 58th International Conference of British Association of Paediatric Surgeons, Belfast, U.K., 19 - 22 July 2011.
Hao W., Chan I.H.Y., Liu X., Tang P.M.Y., Tam P.K.H. and Wong K.K.Y., Early post-operative interleukin-6 and tumour necrosis factor-α levels after single-port laparoscopic varicocelectomy in children, Pediatric Surgery International. 2012, 28(3): 281-286.
Huang J.S., Chung H.Y., Chan I.H.Y., Tao Q., Wong K.K.Y. and Tam P.K.H., Early outcomes of thoracoscopic repair of congenital diaphragmatic hernia (CDH): two centres' experience, IPEG's 21st Annual Congress for Endosurgery in Children, San Diego, U.S.A., 6 - 10 March 2012.
Huang J.S., Tao J.F., Chen K., Dai K.L., Tao Q., Chan I.H.Y., Chung H.Y., Lan L.C.L., Tam P.K.H. and Wong K.K.Y., Thoracoscopic repair of oesophageal atresia: experience of 33 patients from two tertiary referral centres, The 45th Annual Meeting of the Pacific Association of Pediatric Surgeons, Shanghai, China, 3 - 7 June 2012.
Kam K.M., Lee K.Y., Tam P.K.H. and Lui V.C.H., Generation of NSE-MerCreMer transgenic mice with tamoxifen inducible Cre activity in neurons, PLoS One. 2012, 7(5): e35799.
Kam K.M., Cheung M.C.H., Tam P.K.H. and Lui V.C.H., Hoxb5 trans-activates Sox9 and regulates trunk neural crest cell development, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
Lan C.L.L., Chan I.H.Y. and Tam P.K.H., Island flap repair of buried penis, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Lau S.T., Kwok C.K.M., Tam P.K.H. and Ngan E.S.W., Dynamic regulation of c-KIT population in neuroblastoma, The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Leon Y.Y., So M.T., Lui V.C.H., Hofstra R.M.W., Tam P.K.H., Ngan E.S.W. and Garcia-Barcelo M.M., Functional analyses of RET mutations in Chinese Hirschsprung disease patients, Birth Defects Research (Part A): Clinical and Molecular Teratology. 2012, 94(1): 47-51.
Leung J.L., Chung H.Y., Chan I.H.Y., Wong R.M.S., Chan A.W.S., Tam P.K.H. and Wong K.K.Y., The use of omega-3-fatty acid for short bowel syndrome patients accelerates reversal of cholestasis, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Li R., Yang W., Zhang J., Hirankarn N., Pan H.F., Mok C.C., Wong R.W.S., Mok T.M.Y., Lee K.W., Wong S.N., Leung A.M.H., Li X.P., Avihingsanon Y., Lee T.L., Ho M.H.K., Lee P.P.W., Chan T.M., Wong W.H.S., Wong C.M., Ng I.O.L., Yang J., Li P.H., Zhang Y., Zhang L., Li W., Baum L., Kwan P., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Lau W.C.S., Shen N., Lau Y.L. and Ye D.Q., Association of CD247 with systemic lupus erythematosus in Asian populations, Lupus. 2012, 21(1): 75-83.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., Hedgehog-Notch induced premature gliogenesis: a new disease mechanism for Hirschsprung's disease., The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
Ngan E.S.W., Garcia-Barcelo M.M., Yip B.H.K., Poon P.C., Lau C.S.T., Kwok K.M., Sat E.W.Y., Sham M.H., Wong K.K.Y., Wainwright B.J., Cherny S.S., Hui C.C., Sham P.C., Lui V.C.H. and Tam P.K.H., Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung’s disease in mice and humans, Journal of Clinical Investigation. 2011, 121(9): 3467-3478.
Peng J., Chan K.Y., Chen Y., Lamb J.R., Tam P.K.H. and El-Nezamy H.S., Effects of water uptake on melamine renal stone formation in mice, Nephrol Dial Transplant . 2012, 27: 2225-2231.
Peng J., Li D., Chan Y.K., Chen Y., Lamb J.R., Tam P.K.H. and El-Nezamy H.S., Effects of water uptake on melamine renal stone formation in mice, Nephrology Dialysis Transplantation. 2012, 27: 2225-2231.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tam P.K.H., ? TOF (Invited Lecture), The 13th International Paediatric Surgical Week, Kuhtai, Austria, 25 February - 3 March 2012. 2012.
Tam P.K.H., Advances of paediatric minimally invasive surgery in the World and in China (Invited lecture), The 3rd World (21st Chinese) Endoscopy Doctors Conference, Award Ceremony for Endos Award in Medical Science and Technology, Endos World Medical Equipment and Medicine Expo, Beijing, China, 18 - 20 November 2011. 2011.
Tam P.K.H., An unusual liver (Invited Lecture), The 13th International Paediatric Surgical Week, Kuhtai, Austria, 25 February - 3 March 2012. 2012.
Tam P.K.H., Associate Editor, Journal of Pediatric Surgery. 2011.
Tam P.K.H., Basic laparoscopy: splenectomy (Invited lecture), Pediatric Minimally Invasive Surgery: Showcase in Asia (Part 1: Biliary and Solid Organ), Hong Kong, 15 December 2011. 2011.
Tam P.K.H., Board Member, The 39th Annual Combined Meeting of the Scientific Advisory Council and the Board of the Sophia Children's Hospital Foundation, Rotterdam, Netherlands, 17-18 November 2011. 2011.
Tam P.K.H., Editorial Board Member (2010-2014), Chinese Journal of Clinicians. 2011.
Tam P.K.H., Editorial Board Member, Annals of College of Surgeons of Hong Kong. 2011.
Tam P.K.H., Editorial Board Member, Current Pediatric Reviews. 2011.
Tam P.K.H., Editorial Board Member, Pediatric Surgery International. 2011.
Tam P.K.H., Garcia-Barcelo M.M., Tang S.M., Yeung M.Y., Cheng G., Wong E.H.M., Cui L., Cherny S.S. and Sham P.C., Genetic studies of congenital gastrointestinal diseases (Invited Lecture), The 13th SCBA (Society of Chinese Bioscientists in America) International Symposium, Sun Yat-sen University, Guangzhou, China, 25 - 19 July 2011. 2011.
Tam P.K.H., Honorary Professor (July 2009 - June 2012), Shenzhen Children's Hospital, Shenzhen, China. 2011.
Tam P.K.H., Hypertension in children (Invited Lecture), The 13th International Paediatric Surgical Week, Kuhtai, Austria, 25 February - 3 March 2012. 2012.
Tam P.K.H., Latest advances in minimal invasive surgery (Invited Lecture), 廣東省小兒腹腔鏡及胎兒外科新進展學習班, 中國汕頭, 3 August 2011, 2011.
Tam P.K.H., Latest advances in minimal invasive surgery (Invited lecture), Train-the-Trainers Programme in China: visit West China Hospital, Chengdu, China, 1 November 2011. 2011.
Tam P.K.H., Member (July 2011 - June 2013), Board of Directors of the Hong Kong Science and Technology Parks Corporation. 2011.
Tam P.K.H., Member of the Award Panel (2007 - present), China Oxford Scholarship Fund. 2011.
Tam P.K.H., Minimal invasive surgery: development and latest advances (Invited lecture), The 9th Laparoscopic Workshop in China (collaborated with Second Affiliated Hospital, Xian Jiaotong University School of Medicine), Xian, China, 3 - 5 November 2011. 2011.
Tam P.K.H., Minimally Invasive Endoscopy Prestigious Doctors Award (內鏡微創名醫獎), Endos Award in Medical Science & Technology. 2011.
Tam P.K.H., Neuregulins and Hirschsprung disease (Invited Lecture), The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25 - 28 March 2012. 2012.
Tam P.K.H., Reviewer , Journal of Pediatric Surgery. 2011.
Tam P.K.H., Reviewer , Pediatric Surgery International. 2011.
Tam P.K.H., Reviewer, World Journal of Gastroenterology. 2011.
Tam P.K.H., 小兒微創外科發展及培訓 (Invited Lecture), The 10th Laparoscopic Workshop in China (collaborated with Jiangxi Provincial Children’s Hospital), Nanchang, Jiangxi, China, 17 - 20 May 2012. 2012.
Tam P.K.H., Thoracoscopic surgery in neonates and young infants (Invited Lecture), The 13th International Paediatric Surgical Week, Kuhtai, Austria, 25 February - 3 March 2012. 2012.
Tam P.K.H., Tumor suppressive role of Kruppel-like factor (KLF4) in neuroblastoma (Invited lecture), The 70th Annual Meeting of the Japanese Cancer Association, Nagoya, Japan, 3 - 5 October 2011. 2011.
Tam P.K.H., 外科學和生物醫學工程學教授 (2011-2016), 中南大學. 2011.
Tam P.K.H., 第7届委員會內鏡外科學組顧問, 中華醫學會小兒外科學分會. 2011.
Tam P.K.H., 小兒微創外科發展及培訓 (Invited Lecture), 第五届全國小兒外科學中青年醫師學術會議, 中國深圳, 10 May 2012, 2012.
Tam P.K.H., 小儿微创外科发展及培训 (Invited Lecture), 首届中华小儿微创外科学组学术研讨会, Xian, China, 4-5 May 2012, 2012.
Tam P.K.H., 膽道閉鎖的Kasai 手術和肝移植 (Invited Lecture), 2011年廣東省醫學會小兒外科學學術會議, 中國深圳, 16 - 18 December 2011, 2011.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
Tsang J.Y.S., Ratnasothy K., Li D., Chen Y., Bucy R.P., Lau K.F., Smyth L., Lombardi G., Lechler R. and Tam P.K.H., The potency of allospecific tregs cells appears to correlate with T cell receptor functional avidity, American Journal of Transplantation. 2011, 11(8): 1610-1620.
Wong K.K.Y. and Tam P.K.H., Biliary atresia Kasai or liver transplantation? (Invited Lecture), International Surgical Week 2011, Pacifico Yokohama, Japan, 28 August - 1 September 2011. 2011.
Wong K.K.Y., Wu X.Z., Chan I.H.Y. and Tam P.K.H., Evaluation of defecative function 5 years or longer after laparoscopic-assisted pull-through for imperforate anus, Journal of Pediatric Surgery. 2011, 46(12): 2313-2315.
Wong K.K.Y., Li L., Li S.L. and Tam P.K.H., Experience of setting up laparoscopic workshops in China: a 4-year review, The International Pediatric Endosurgery Group's 21st Annual Congress for Endosurgery in Children, San Diego, U.S.A., 6 - 10 March 2012.
Wong K.K.Y. and Tam P.K.H., Omphalomesenteric duct remnants, In: Puri P. (ed.), Newborn Surgery, 3rd edition. London, Hodder Arnold, 2011.
Yung S.Y.J., Tse H.F., Tam P.K.H. and Ngan E.S.W., Establishing a patient-specific iPSC model for Hirschsprung’s disease and other neural crest-associated diseases, The 10th Annual Meeting of the International Society for Stem Cell Research, Yokohama, Japan, 13 - 16 June 2012.
Yung S.Y.J., Chow H.M., Tse H.F., Tam P.K.H. and Ngan E.S.W., Generation of patient-specific iPSCs for Hirschsprung's disease modelling, Days of Molecular Medicine 2011, Hong Kong, 10-12 November 2011.
Yung S.Y.J., Tse H.F., Wan T.S.K., Tam P.K.H. and Ngan E.S.W., Modelling Hirschsprung’s disease using patient-specific iPS cells, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25 - 28 March 2012.
Yung S.Y.J., Tse H.F., Tam P.K.H. and Ngan E.S.W., iPS cell-derived neural crest cells from a patient with Hirschsprung's disease show a reduced differentiation plasticity, The 10th Annual Meeting of the International Society for Stem Cell Research, Yokohama, Japan, 13 - 16 June 2012.
Zhang M., Leung C., Sit H.M., Chu K.H., Lui V.C.H., Tam P.K.H. and Sham M.H., Sox10 NGFP mutation affects migration of enteric neural cress cells in mouse embryonic gut, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March, 2012.
Zhou M., Xu A., Tam P.K.H., Lam K.S.L., Huang B., Liang Y., Lee I.K., Wu D.H. and Wang Y., Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K, PLoS One. 2012, 7(2): e32349.
Zhu J., Garcia-Barcelo M.M., Tam P.K.H. and Lui V.C.H., RET transcriptional regulation by HOXB5 in Hirschsprung's disease, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.


Researcher : Tang WY

List of Research Outputs

Tang W.Y., Curcumin inhibits cancer cells migration and invasion of tongue carcinoma through down-regulation of matrix metalloproteinase-10, Dissertation, Master of Philosophy, The University of Hong Kong. 2012.
Tsang R.K.Y., Tang W.Y., Gao W., Ho W.K., Chan Y.W., Wei W.I. and Wong S.T.S., Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10, Cancer Investigation. 2012, 30(7): 503-512.


Researcher : Tang WY

List of Research Outputs

Tang W.Y., Curcumin inhibits cancer cells migration and invasion of tongue carcinoma through down-regulation of matrix metalloproteinase-10, Dissertation, Master of Philosophy, The University of Hong Kong. 2012.
Tsang R.K.Y., Tang W.Y., Gao W., Ho W.K., Chan Y.W., Wei W.I. and Wong S.T.S., Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10, Cancer Investigation. 2012, 30(7): 503-512.


Researcher : Tang YF

List of Research Outputs

Tang Y.F., Retrospective evaluation of the Barcelona clinic liver cancer staging classification and treatment schedule and development of a new prognsotic staging system with treatment guidelines for Hong Kong patients with hepatocellular carcinoma, Dissertation, Master of Philosophy, The University of Hong Kong. 2012.


Researcher : Tian L

Project Title:Basic Sciences Symposium 2003: Transplantation Immunology in the Real World Orthotopic Small Bowel but not Heterotopic Cardiac Allograft Recipients Treated with an Unique FK506 Regimen Contributes to the Induction of Egulatory T Cells
Investigator(s):Tian L
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2003




Researcher : Ting ACW

List of Research Outputs

Chan Y.C., Ting A.C.W., Yiu W.K. and Cheng S.W.K., Successful emergency endovascular treatment of juxtarenal and infrarental mycotic aortic aneurysms in patients with small diameter aortae using Cook Zenith ESLE stentgrafts, World Journal of Emergency Medicine. 2012, 3(2): 146-149.
Szeto G.P.Y., Cheng S.W.K., Poon J.T.C., Ting A.C.W., Tsang R.C.C. and Ho P., Surgeons' static posture and movement repetitions in open and laparoscopic surgery, Journal of Surgical Research. 2012, 172(1): e19-e31.
Ting A.C.W., Access complications from endovascular interventions, Hong Kong Surgical Forum, Hong Kong, 14 January 2012. 2012.
Ting A.C.W., DVT in surgical patients in Hong Kong, Symposium of Venous Disease 2011, Department of Surgery, Kwong Wah Hospital, Hong Kong, 12 October 2011. 2011.
Ting A.C.W., Invited Chairman for "Peripheral Interventions", Hong Kong Surgical Forum - Winter, The University of Hong Kong, Hong Kong, 14 January 2012. 2012.
Yiu W.K., Chan Y.C., Ting A.C.W. and Cheng S.W.K., Para-aortic lymphoma mimicking mycotic abdominal aortic aneurysm: case presentation & review of literature (Poster Presentation), The 12th Annual Congress of the Asian Society for Vascular Surgery (ASVS) and 6th Asian Venous Forum, Taipei, Taiwan, 29 September to 2 October 2011.


Researcher : To VSH

Project Title:The role of microRNA let 7 in controlling proliferation of nasopharyngeal carcinoma cells
Investigator(s):To VSH, Wong STS
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2010


Project Title:Comparison of Endoscopic Thyroidectomy via Bilateral Axillo-Breast Approach and Transaxillary Approach: A Randomized Pilot Study
Investigator(s):To VSH
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2012


List of Research Outputs

Chan Y.W., Lee V.H.F., Chow V.L.Y., To V.S.H. and Wei W.I., Extracapsular lymph node spread in recurrent nasopharyngeal carcinoma, Laryngoscope. 2011, 121(12): 2576-2580.
Chan Y.W., To V.S.H. and Wei W.I., Extracapular lymph node spread in recurrent nasopharyngeal carcinoma, Laryngoscope. 2011, 12(1): 2576-2580.
Chan Y.W., To V.S.H., Wong S.T.S. and Wei W.I., Quality of dying in head and neck cancer patients: the role of surgical palliation, European Archives of Oto-Rhin-Laryngology. 2012, Epub on 5 June 2012.
Chung J.C.K., Tsang R.K.Y., To V.S.H., Ho C.W.A., Chan Y.W., Ho W.K. and Wei W.I., Secondary head and neck cancer in patients with history of haematological malignancy, Head & Neck. 2012, Epub on 15 May 2012.
Ho C.W.A., Lee V.H.F., To V.S.H., Kwong D.L.W. and Wei W.I., Natural course and tumor doubling time of nasopharyngeal carcinoma. A study of 15 patients, Oral oncology. Elsevier, 2011, 47(8): 742-6.
To V.S.H., Anatomical and functional considerations of laryngo-pharyngeal surgery, Head & Neck Course 2012, Hong Kong, 7-8 June 2012. 2012.
To V.S.H., Anatomy and function of the oral cavity, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
To V.S.H., Head and neck infections and complications, The 18th ENT Course for Nurses, Hong Kong, 30 April 2012. 2012.
To V.S.H., Chan Y.W., Tsang R.K.Y. and Wei W.I., Review of salivary gland neoplasms, ISRN Otolaryngology. 2012, 2012.
To V.S.H. and Wong S.T.S., Structural disturbance and reconstruction of glossectomy patients, In: Katô H. and Shimizu T. (eds.), Tongue: Anatomy, Kinematics and Diseases (Human Anatomy and Physiology). Hauppauge, New York, Nova Science, 2012, 73-88.
Wei W.I. and To V.S.H., Management of neck metastases of nasopharyngeal carcinoma, In: Cernea C.R., Dias F.L., Fliss D., Lima R.A., Myers E.N. and Wei W.I. (eds.), Pearls and Pitfalls in Head and Neck Surgery, 2nd revised and extended edition. Basel, Switzerland, Karger, 2012, 102-103.


Researcher : Tong DKH

List of Research Outputs

Law Y., Tong D.K.H. and Law S.Y.K., Efficacy and safety of self-expanding plastic stent (SEPS) in the management of esophageal disorders (Abstract), Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Tong D.K.H., Endoscopic radiofrequency ablation for esophageal lesion, Advances in Endoscopy 2012, Departments of Surgery and Medicine, Queen Mary Hospital and Tung Wah Hospital, Hong Kong, 24 March 2012. 2012.
Tong D.K.H., Epiphrenic esophageal diverticulum, Session on "GERD and Hernia", Hong Kong Society of Upper Gastrointestinal Surgeons Foregut Disorder Workshop, Department of Surgery, The University of Hong Kong, Li Ka Shing Faculty of Medicine, Hong Kong, 9-10 March 2012. 2012.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., Extra Free Paper Session: What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer? (Abstract), Annual Scientific Meeting 2011, The College of Surgeons of Hong Kong and Macau Surgical Association, Hong Kong, 17 - 18 September 2011.
Tong D.K.H., Law S.Y.K. and Chan S.Y., Operative outcomes of colonic interposition in the treatment of esophageal cancer: a three decades experience (Abstract), Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Tong D.K.H. and Law S.Y.K., Post-oesophagectomy anastomotic-bronchial fistula (Case Report), Hong Kong Medical Journal. 2011, 17(4): 325-327.
Tong D.K.H., Law S.Y.K. and Chan S.Y., Robotic-assisted esophageal epiphrenic diverticulectomy, myotomy and Dor Hemi-Fundoplication (Video Abstract), Digestive Disease Week 2012, San Diego, California, U.S.A., 19 - 22 May 2012.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, Session on "ISDS Free Papers, Esophagus 1: Malignant", (Abstract), The International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer?, Surgical Practice. 2011, 15(Suppl 2): B7.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, World Journal of Surgery. 2011, 35(Suppl 1): S172.
Wong W.H., Wong H.T., Tong D.K.H., Leung G.K.K. and Yuen W.K., Utilization of whole body computed tomography (WB-CT) for trauma patients, The Advanced Trauma Life Support Region XVI Meeting, Malaysia. 2012.
Yam P.P.C., Tong D.K.H. and Law S.Y.K., Hong Kong dollar in the oesophagus (Pictorial Medicine), Hong Kong Medical Journal. 2012, 18(2): 166.
Yam P.P.C., Tong D.K.H. and Law S.Y.K., The 7th Edition American Joint Cancer Committee Staging System for esophageal cancer - A better staging system compared to the old one? (Abstract) "Free Paper Session", Annual Scientific Meeting 2011, The College of Surgeons of Hong Kong & Macau Surgical Association, Hong Kong, 17 - 18 September 2011.
Yam P.P.C., Tong D.K.H. and Law S.Y.K., The 7th Edition American Joint Cancer Committee Staging System for esophageal cancer - a better staging system compared to the old one?, Surgical Practice. 2011, 15(Suppl 2): B3.


Researcher : Tsang CO

List of Research Outputs

Tsang C.O., Leung K.M., Leung G.K.K. and Lui W.M., Carotid blowout syndrome: EC-IC bypass and endovascular management of ruptured radiation-related pseudoaneurym in nasopharyngeal cancer patients, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.


Researcher : Tsang COA

List of Research Outputs

Leung G.K.K. and Tsang C.O.A., External ventricular drian infections - can an extended subcutaneous tunnel reduce infection rate?, In: Pant S. and Cherian I. (eds.), Hydrocephalus. Croatia, InTech, 2012, 87-98.
Tsang C.O.A., Leung G.K.K. and Lui W.M., Best Oral Free Paper in General Neurosurgery (non-HST), The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011. 2011.
Zhang X., Sun S., Pu J.K.S., Tsang C.O.A., Lee D., Lui W.M., Wong S.T.S., Leung G.K.K. and Man V.O.Y., Long non-coding RNA expression profiles predict clinical phenotypes in glioma, Neurobiology of Disease. 2012, 48(1): 1-8.


Researcher : Tsang FH

List of Research Outputs

Fatima S., Lee N.P.Y., Tsang F.H., Kolligs F.T., Ng I.O.L., Poon R.T.P., Fan S.T. and Luk J.M.C., Dickkopf 4 (DKK4) acts on Wnt/β-catenin pathway by influencing β-catenin in hepatocellular carcinoma, Oncogene. 2012, Epub on 2012-01-16.


Researcher : Tsang JYS

List of Research Outputs

Li W.Y., Lam W.W.T., Au A.H.Y., Ye M., Law W.L., Poon J.T.C., Kwong A., Suen D.T.K., Tsang J.Y.S., Girgis A. and Fielding R., Interpreting differences in patterns of supportive care needs between patients with breast cancer and patients with colorectal cancer, Psychooncology. 2012, Epub ahead of print.
Tsang J.Y.S., Ratnasothy K., Li D., Chen Y., Bucy R.P., Lau K.F., Smyth L., Lombardi G., Lechler R. and Tam P.K.H., The potency of allospecific tregs cells appears to correlate with T cell receptor functional avidity, American Journal of Transplantation. 2011, 11(8): 1610-1620.


Researcher : Tsang RKY

Project Title:Evaluation of the anti-migration effects of curcumin in squamous cell carcinoma of tongue
Investigator(s):Tsang RKY, Wong STS
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2010
Completion Date:06/2012


Project Title:Bone-anchored hearing aid for the hearing impaired not suitable for conventional hearing aids
Investigator(s):Tsang RKY, Ho WK, Au DKK, Wong BYH
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:03/2012


Project Title:The effect of surgical treatment of oesophageal cancer on oral and pharyngeal phases of swallowing
Investigator(s):Tsang RKY
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012


Project Title:15th Asian Research Symposium in Rhiniology Combined Robotic and Endoscopic Nasopharyngectomy for Recurrent Nasopharyngeal Carcinoma
Investigator(s):Tsang RKY
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2012
Completion Date:05/2012


List of Research Outputs

Chung J.C.K., Tsang R.K.Y., To V.S.H., Ho C.W.A., Chan Y.W., Ho W.K. and Wei W.I., Secondary head and neck cancer in patients with history of haematological malignancy, Head & Neck. 2012, Epub on 15 May 2012.
Lam W.K., Tsang R.K.Y., Leung G.K.K. and Ho W.K., Management of profuse epistaxis in post-irradiated nasopharyngeal carcinoma patients, The 15th Asian Research Symposium on Rhinology, Singapore, 24 - 26 May 2012.
To V.S.H., Chan Y.W., Tsang R.K.Y. and Wei W.I., Review of salivary gland neoplasms, ISRN Otolaryngology. 2012, 2012.
Tsang R.K.Y., Clinical features of common oral pathologies, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
Tsang R.K.Y., Ho W.K. and Wei W.I., Combined robotic and endoscopic nasopharyngectomy for recurrent nasopharyngeal cancer, The 15th Asian Research Symposium in Rhinology, Singapore, 24 - 26 May 2012.
Tsang R.K.Y., Complications following surgery for intra-oral pathologies, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2011.
Tsang R.K.Y., Council Member (Jan 2012- present), Hong Kong Society of Otorhinolaryngology-Head and Neck Surgery. 2012.
Tsang R.K.Y., Tang W.Y., Gao W., Ho W.K., Chan Y.W., Wei W.I. and Wong S.T.S., Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10, Cancer Investigation. 2012, 30(7): 503-512.
Tsang R.K.Y., Endoscopic surgery for tumours in the nasal cavity and paranasal sinuses, 2011 International & the 11th National Conference on Head and Neck Oncology, Hangzhou, China, 2011. 2011.
Tsang R.K.Y. and Ho W.K., Endoscopic treatment of eye diseases, Hong Kong Surgical Forum - Summer, The University of Hong Kong, Hong Kong, 16 July 2011. 2011.
Tsang R.K.Y., Epidemiology and nature of laryngo-pharyngeal cancer, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2012.
Tsang R.K.Y., Examiner (2009- present), Mock Examination of the Hong Kong College of Otorhinolaryngology Exit Examination. 2011.
Tsang R.K.Y., Executive Committee Member (July 2007 – present), Hear Talk Foundation. 2012.
Tsang R.K.Y. and Mohr C., Lateral palatal flap approach to the nasopharynx and parapharyngeal space for transoral robotic surgery: a cadaveric study, Journal of Robotic Surgery. 2012, Epub on 24 April 2012.
Tsang R.K.Y., Organ preserving surgery for laryngo-pharyngeal cancer, Head & Neck Course 2011, Hong Kong, 25-26 August 2011. 2012.
Tsang R.K.Y., Organizer for the course "Endoscopic Skull Base Surgery”, Hospital Authority Commissioned Training in ENT - January 2012. 2012.
Tsang R.K.Y., Peer Reviewer, Head and Neck Journal. 2012.
Tsang R.K.Y., Peer Reviewer, ORL. 2012.
Tsang R.K.Y., Peer reviewer, Surgical Practice. 2012.
Tsang R.K.Y., Robotic surgery for head and neck tumours, Scientific Meeting of Hong Kong Head and Neck Society, Hong Kong, 2012. 2012.
Tsang R.K.Y., Gao W. and Wong S.T.S., Surgical treatment of the squamous cell carcinoma of the tongue and the effect on speech and swallowing, In: Kato H. and Shimizu T. (eds.), Tongue: Anatomy, Kinematics and Diseases (Human Anatomy and Physiology). Hauppauge, New York, Nova Science, 2012, 1-16.
Wong S.T.S., Gao W., Ho W.K., Chan Y.W. and Tsang R.K.Y., MicroRNA dysregulation in squamous cell carcinoma of head and neck, In: Li X. (ed.), Squamous Cell Carcinoma. Rijeka, Croatia, Intech, 2011, 255-280.


Researcher : Tsoi LS

List of Research Outputs

Tsoi L.S., Tumor suppressive functions of kruppel-like factor 4 (KLF4) in neuroblastoma, Dissertation, Master of Philosophy, The University of Hong Kong. 2011.


Researcher : Tsui TY

Project Title:54th Annual Meeting of the American Association for the Study of Liver Diseases Controlling the Development of Liver Cirrhosis by rAAV Mediated Stable HO-1 Expression
Investigator(s):Tsui TY
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2003


Project Title:Identification possible role of heme oxygenase-1 on the regulation of T cell activation
Investigator(s):Tsui TY
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2004




Researcher : Wan TMH

List of Research Outputs

Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Lam C.T., Yang Z., Ng N.P., Wan T.M.H., Lau J.C.S., Ho D.W.Y., Fan S.T. and Poon R.T.P., The potential role of CD44 in liver regeneration, The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.


Researcher : Wang H

List of Research Outputs

Li W., Jiang W., Zhou Z., Wang H. and Fan S.T., 中國器官獲取與移植監測網絡, 中華移植雜誌 (電子版), 2012, 6: 1-5.


Researcher : Wang X

Project Title:Importance of DNA damage mediated S and G2 checkpoint as a protective mechanism in stem cells
Investigator(s):Wang X, Lui VCH
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2008
Completion Date:08/2011


Project Title:The link between adult stem cells and chimerism of liver transplantation
Investigator(s):Wang X
Department:Surgery
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


Project Title:Cell cycle regulation and drug resistance in stem and cancer stem cells
Investigator(s):Wang X
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2010
Completion Date:11/2011


Project Title:Potential DNA repair mediated chemotherapeutic resistance in hepatocellular carcinoma
Investigator(s):Wang X
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:AACR annual meeting 2012 Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver
Investigator(s):Wang X
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:04/2012


Project Title:DNA damage induces stem cell differentiation through potential Akt regulated checkpoint activation
Investigator(s):Wang X
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Wang X., Chan K.K., Lui V.C.H. and Norbury C., G1 checkpoint establishment and associated DNA repair kinetics in vivo during embryonic liver development (Abstract), ISSCR Annual Meeting 2012, Yokohama, Japan, 13 June 2012.
Wang X., Lo C.M. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver (Abstract), The American Association for Cancer Research Annual Meeting 2012, Chicago, Illinois, U.S.A., 31 March - 4 April 2012.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.
Wang X., Listed in Who's Who in the World, edition 2012, Who's Who in the World (a directory containing short biographies, published by Marquis Who's Who, an American publisher), edition 2012. 2012.
Wang X., Zhang W., Lui E.L.H., Zhu Y., Lu P., Yu X., Sun J., Yang S., Poon R.T.P. and Fan S.T., Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma, International Journal of Cancer. 2011, 131(3): E163-172.
Wu C., Miao X., Huang L., Che X., Jiang G., Yu D., Yang X., Cao G., Hu Z., Zhou Y., Zuo C., Wang C., Zhang X., Zhou Y., Yu X., Dai W., Wang X. and Cheung S.T., Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations, Nature Genetics. 2011, 44(1): 62-66.


Researcher : Wang Y

List of Research Outputs

Lee N.P.Y., Wang Y. and Luk J.M.C., Monoclonal antibody against cadherin-17 as a potential treatment for liver cancer (Poster & Abstract), The 47th Annual Meeting of the European Association for the Study of the Liver and the International Liver Congress 2012, Barcelona, Spain, 18-22 April 2012.
Leung G.K.K., Wang Y., Un T. and Wu W., An animal study comparing electrocautery and nanopeptide scaffold in neurosurgical haemostasis, The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Leung G.K.K., Wang Y. and Wu W., Peptide nanofiber scaffold for brain tissue reconstruction, In: Duzgunes N. (ed.), Methods in Enzymology. Volume 508. Nanomedicine: Cancer, Diabetes, and Cardiovascular, Central Nervous System, Pulmonary and Inflammatory Diseases. San Diego, Academic Press, 2012, 177-190.


Researcher : Wang Y

List of Research Outputs

Lee N.P.Y., Wang Y. and Luk J.M.C., Monoclonal antibody against cadherin-17 as a potential treatment for liver cancer (Poster & Abstract), The 47th Annual Meeting of the European Association for the Study of the Liver and the International Liver Congress 2012, Barcelona, Spain, 18-22 April 2012.
Leung G.K.K., Wang Y., Un T. and Wu W., An animal study comparing electrocautery and nanopeptide scaffold in neurosurgical haemostasis, The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Leung G.K.K., Wang Y. and Wu W., Peptide nanofiber scaffold for brain tissue reconstruction, In: Duzgunes N. (ed.), Methods in Enzymology. Volume 508. Nanomedicine: Cancer, Diabetes, and Cardiovascular, Central Nervous System, Pulmonary and Inflammatory Diseases. San Diego, Academic Press, 2012, 177-190.


Researcher : Wei WI

Project Title:Intra-arterial chemoradiation for advanced head and neck cancer
Investigator(s):Wei WI, Sham JST
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:07/2002


Project Title:Quantitative analysis of plasma Epstein-Barr-Virus DNA in nasopharyngeal carcinoma after salvage nasopharyngectomy
Investigator(s):Wei WI
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:09/2002


Project Title:Modifications of techniques of cochlear implantation
Investigator(s):Wei WI, Au DKK, Ho WK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:09/2002


Project Title:Management of snoring and OSA
Investigator(s):Wei WI, Ho WK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:09/2002


Project Title:VEGF in nasopharyngeal cancer
Investigator(s):Wei WI, Kwong DLW, Poon RTP
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:03/2003


Project Title:Study the spread of aerosol during tracheostomy or intubation
Investigator(s):Wei WI, Sham JST, Irwin MG
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:04/2003


Project Title:Head and neck course in China - to teach techniques of contemporary operations and patient care for doctors and nurses working in underdeveloped areas in China. This will benefit those poor patients suffereing from head and neck cancer in China
Investigator(s):Wei WI, Lam LK, Hui Y, Ng WM
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2003


Project Title:Cochlear implant for 14 profoundly deaf children in China
Investigator(s):Wei WI, Au DKK, Hui Y
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2003


Project Title:Speech rehabilitation after total laryngectomy - self help and mutual help
Investigator(s):Wei WI, Ho WK
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2003


Project Title:Cochlear implant for 14 profoundly deaf Chinese children in China
Investigator(s):Wei WI, Hui Y, Au DKK
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/2005


Project Title:Head and neck course in China - to teach techniques of contemporary operations and patient care for doctors and nurses working in relatively underdeveloped areas in China
Investigator(s):Wei WI, Lam LK, Hui Y
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/2005


Project Title:Speech rehabilitation after total laryngectomy - self help and mutual help
Investigator(s):Wei WI
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/2005


Project Title:Bone-anchored hearing aid for the severe deaf patients
Investigator(s):Wei WI, Ho WK, Au DKK
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/2007


Project Title:Speech rehabilitation after total laryngectomy - self help and mutual help
Investigator(s):Wei WI
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2007


Project Title:Head and neck course in China - to introduce techniques of contemporary operations and patient care for doctors and nurses working in relatively underdeveloped areas in China
Investigator(s):Wei WI, Ng WM, Ho WK
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2007


Project Title:American Academy of Otolaryngology - Head and Neck Surgery 2007 Annual Meeting Nasopharyngeal cancer: early diagnosis, treatment and salvage
Investigator(s):Wei WI
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2007


Project Title:Three-dimensional evaluation of tumor extension patterns of nasopharyngeal carcinoma
Investigator(s):Wei WI, Wong STS
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2008


Project Title:Head and neck course in China - to introduce current surgical techniques and patient care for doctors and nurses working in relatively underdeveloped areas in China
Investigator(s):Wei WI, Ng WM, Ho WK
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2008


Project Title:Brainstem implant for 6 profoundly deaf Chinese patients
Investigator(s):Wei WI, Ho WK, Au DKK
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Head and neck course in China – to update current surgical techniques and patient care options for doctors and nurses in relatively underdeveloped areas in China
Investigator(s):Wei WI, Chan YW, Ho WK
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Speech rehabilitation after total laryngectomy – self help and mutual help
Investigator(s):Wei WI, To VSH
Department:Surgery - Otorhinolaryngology Un
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


List of Research Outputs

Chan Y.W., Ng W.M. and Wei W.I., Anatomical study and clinical applications of free posterior tibial flap in the Head and Neck region, Plastic and Reconstructive Surgery. 2011, 128(3): 131e-139e.
Chan Y.W. and Wei W.I., Clinical application of the free posterior tibial flap in the oral cavity, The 3rd World Congress of the International Academy of Oral Oncology (IAOO) – Yin and Yang: Balancing Cure and Consequences, Singapore, 14 – 17 July 2011.
Chan Y.W. and Wei W.I., Critical appraisal of maxillary swing approach for nasopharyngeal carcinoma, Expert Opinion on Therapeutic Targets. 2012, 16(S1): S111-S117.
Chan Y.W. and Wei W.I., Current management strategy of hypopharyngeal carcinoma, Auris Nasus Larynx. 2012, Epub ahead of print.
Chan Y.W., Lee V.H.F., Chow V.L.Y., To V.S.H. and Wei W.I., Extracapsular lymph node spread in recurrent nasopharyngeal carcinoma, Laryngoscope. 2011, 121(12): 2576-2580.
Chan Y.W., To V.S.H. and Wei W.I., Extracapular lymph node spread in recurrent nasopharyngeal carcinoma, Laryngoscope. 2011, 12(1): 2576-2580.
Chan Y.W. and Wei W.I., Nasopharyngectomy for locally advanced recurrent nasopharyngeal carcinoma: is there a limit?, The 3rd World Congress of the International Academy of Oral Oncology (IAOO) – Yin and Yang: Balancing Cure and Consequences, Singapore, 14 – 17 July 2011.
Chan Y.W., To V.S.H., Wong S.T.S. and Wei W.I., Quality of dying in head and neck cancer patients: the role of surgical palliation, European Archives of Oto-Rhin-Laryngology. 2012, Epub on 5 June 2012.
Chan Y.W., Chow V.L.Y. and Wei W.I., Quality of life of patients after salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma, Cancer. 2011, 118(15): 3710-3718.
Chan Y.W. and Wei W.I., Recurrent nasopharyngeal carcinoma after salvage nasopharyngectomy, Archives of Otolaryngology-Head and Neck Surgery. 2012, 138(6): 572-576.
Cheung J.P.Y., Wei W.I. and Luk K.D.K., Cervical spine complications after treatment of nasopharyngeal carcinoma, 31st Annual Congress of the Hong Kong Orthopaedic Association, Hong Kong, November 19-20, 2011.
Chow V.L.Y., Chan Y.W., Chan R.C., Chung H.P. and Wei W.I., Basal cell carcinoma of the head and neck region in ethnic Chinese, International Journal of Surgical Oncology. 2011, Epub on 14 September 2011.
Chung J.C.K., Tsang R.K.Y., To V.S.H., Ho C.W.A., Chan Y.W., Ho W.K. and Wei W.I., Secondary head and neck cancer in patients with history of haematological malignancy, Head & Neck. 2012, Epub on 15 May 2012.
Gao W., Chan Y.W., Wei W.I. and Wong S.T.S., Anti-Cancer effects of curcumin on head and neck cancer, Anticancer Agents in Medical Chemistry. 2012, Epub on 2 May 2012.
Ho C.W.A., Lee V.H.F., To V.S.H., Kwong D.L.W. and Wei W.I., Natural course and tumor doubling time of nasopharyngeal carcinoma. A study of 15 patients, Oral oncology. Elsevier, 2011, 47(8): 742-6.
Lau G.S.K., Chan Y.W. and Wei W.I., Role of surgery in the treatment of radiation-induced sarcomas of the head and neck, Journal of Cell Science and Therapy. 2011, S2:002.
Lund V.J., Chisholm E.J., Howard D.J. and Wei W.I., Sinonasal malignant melanoma: an analysis of 115 cases assessing outcomes of surgery, postoperative radiotherapy and endoscopic resection, Rhinology. 2012, 50(2): 203-210.
To V.S.H., Chan Y.W., Tsang R.K.Y. and Wei W.I., Review of salivary gland neoplasms, ISRN Otolaryngology. 2012, 2012.
Tsang R.K.Y., Ho W.K. and Wei W.I., Combined robotic and endoscopic nasopharyngectomy for recurrent nasopharyngeal cancer, The 15th Asian Research Symposium in Rhinology, Singapore, 24 - 26 May 2012.
Tsang R.K.Y., Tang W.Y., Gao W., Ho W.K., Chan Y.W., Wei W.I. and Wong S.T.S., Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10, Cancer Investigation. 2012, 30(7): 503-512.
Wei W.I., Academic Advisory Committee Member (April 1998 - present), Diploma Course in Oncology for Health Care Professionals, Queen Mary Hospital Cancer Centre and SPACE, The University of Hong Kong. 2011.
Wei W.I., Advisor (December 2010 - present), Hong Kong Cancer Fund. 2011.
Wei W.I., Advisory Board Member (August 2008 – present), Head and Neck Oncology. 2011.
Wei W.I., Advisory Professor (June 2004 – present), 寧夏醫學院附屬醫院. 2011.
Wei W.I., Advisory Professor (March 2002 – present), 鄭州大學. 2011.
Wei W.I., Alumni Member (1981 - present), Bernard O'Brien Society, The Microsurgery Research Centre, Australia. 2011.
Wei W.I., Assistant Medical Superintendent (January 2011 – Present), Hong Kong Sanatorium & Hospital. 2011.
Wei W.I., Associate Editor (August 2008 - present), Japanese Journal of Clinical Oncology. 2011.
Wei W.I., Benign and malignant parotid tumors – extent of parotidectomy (Invited Lecture), 2012 Annual Meeting and International Conference of Taiwan Head and Neck Society Changhua, Taiwan, 9-10 June 2012. 2012.
Wei W.I., Chairman, Hong Kong Sanatorium & Hospital. Scientific Symposium, Hong Kong, 2 December 2011. 2011.
Wei W.I., Chairman, Surgical Forum by Hong Kong Sanatorium & Hospital and University of California, San Francisco, Hong Kong, 21 July 2011. 2011.
Wei W.I., Consultant ENT Surgeon (January 1988 - present), University Health Clinic, The University of Hong Kong. 2011.
Wei W.I., Corresponding Fellow (April 1995 - present), American Laryngological Association. 2011.
Wei W.I., Corresponding Member (April 1997 – present), American Academy of Otolaryngology - Head and Neck Surgery. 2011.
Wei W.I., Corresponding Member (October 1998 – present), American Head and Neck Society. 2011.
Wei W.I., Council Member (2003 - present), Hong Kong College of Otorhinolaryngologists. 2011.
Wei W.I., Director (June 2010 – June 2014), International Federation of Head and Neck Oncologic Societies. 2011.
Wei W.I., Director, Deputy Secretary and China Chapter Chair (June 2010 - present), Pan Asia Academy of Facial Plastic and Reconstructive Surgery. 2011.
Wei W.I., Editorial Board Honorary Member (1999 - present), Chinese Journal of Cancer. 2011.
Wei W.I., Editorial Board Member (1996 – present), Chinese Journal of Otolaryngology. 2011.
Wei W.I., Editorial Board Member (2003 - present), Medical Progress. 2011.
Wei W.I., Editorial Board Member (2005-7 – present), Skull Base. 2011.
Wei W.I., Editorial Board Member (August 2007 – September 2011, October 2011 – September 2012), The Laryngoscope. 2011.
Wei W.I., Editorial Board Member (February 2011 - present), Recent Advances in ENT. 2011.
Wei W.I., Editorial Board Member (January 1997 - present), Journal of Clinical Otorhinolaryngology (China). 2011.
Wei W.I., Editorial Board Member (January 2008 – December 2011), The Hong Kong Medical Diary. 2011.
Wei W.I., Editorial Board Member (May 1997 - present), The Asean ORL Head and Neck Journal. 2011.
Wei W.I., Editorial Board Member (November 1994 – present), The American Journal of Otolaryngology. 2011.
Wei W.I., Editorial Board Member (November 2006 – present), Chinese Archives of Otolaryngology & Head and Neck Surgery. 2011.
Wei W.I., Editorial Board Member (November 2010 – present), International Journal of Clinical Medicine. 2011.
Wei W.I., Editorial Board Member (October 1995 - present), Chinese Journal of Clinical Oncology. 2011.
Wei W.I., Elected Council Member (December 2009 - present), Hong Kong Academy of Medicine. 2011.
Wei W.I., Evolution of mandibular reconstruction (Invited Lecture), The 4th International Conference of Facial Plastic and Cosmetic Surgery and Founding Congress of PAAFPRS China Academy Chengdu, China, 18-19 August 2011. 2011.
Wei W.I., Executive Council Member (2009 – present), SLOBA Medical Link, St. Louis College, Hong Kong. 2011.
Wei W.I., Expert Panel (March 2007 – present), Policies on the Introduction of New Technology, Cyberknife Stereotactic Radiosurgery, The College of Surgeons of Hong Kong. 2011.
Wei W.I., External Assessor (13 May 2011 – 30 April 2014), Department of Otorhinolaryngology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia. 2011.
Wei W.I., Guest Professor (October 2002 – present), Tongji Medical College, Huazhong University of Science & Technology, China. 2011.
Wei W.I., Head (July 2010 - Present), Department of Surgery, Hong Kong Sanatorium & Hospital, Hong Kong. 2011.
Wei W.I., Head and neck cancer in the developing world (Invited Lecture), Tri-Society Head and Neck Oncology Meeting, Singapore, 1-3 September 2011. 2011.
Wei W.I., Honorary Advisor (1987 - present), The New Voice Club of Hong Kong. 2011.
Wei W.I., Honorary Advisor (February 1995 - present), Kin Lok Club, Hong Kong (Nasopharyngeal Carcinoma patient support group). 2011.
Wei W.I., Honorary Advisor (October 1995 – present), Driver Rehabilitation Service, ReHabAid Centre, Hong Kong Polytechnic University, Hong Kong. 2011.
Wei W.I., Honorary Consultant in Otorhinolaryngology (January 2009 – December 2011), Hong Kong Sanatorium & Hospital. 2011.
Wei W.I., Honorary Director (December 1997 – present), The First Medical School, West China University of Medical Sciences, Chengdu, China. 2011.
Wei W.I., Honorary Fellow (February 2000 - present), Philippine Society of Otolaryngology-Head and Neck Surgery, Philippines. 2011.
Wei W.I., Honorary Fellow (May 2006 - present), German Society of Otolaryngology and Head & Neck Surgery. 2011.
Wei W.I., Honorary Medical Advisor (August 1994 - present), The Cancer Crusade Angels Service Society of Hong Kong. 2011.
Wei W.I., Honorary Member (September 1997 - present), Philippine Academy for Head & Neck Surgery, Philippines. 2011.
Wei W.I., Honorary Professor (August 2007 - present), Department of Otolaryngology, Xiang Ya Hospital, Central South University, Hunan, China. 2011.
Wei W.I., Honorary Professor (February 2006 – present), The First Affiliated Hospital of Chongqing Medical Sciences. 2011.
Wei W.I., International Advisor Board Member (2001 - present), Otolaryngology Head and Neck Surgery, American Academy of Otolaryngology, Head & Neck Surgery. 2011.
Wei W.I., International Editorial Board Member (February 2007 – present), The Clinical and Experimental Otorhinolaryngology. 2011.
Wei W.I., International Editorial Board Member (September 2010 – present), Acta Oto-Laryngolocia. 2011.
Wei W.I. and To V.S.H., Management of neck metastases of nasopharyngeal carcinoma, In: Cernea C.R., Dias F.L., Fliss D., Lima R.A., Myers E.N. and Wei W.I. (eds.), Pearls and Pitfalls in Head and Neck Surgery, 2nd revised and extended edition. Basel, Switzerland, Karger, 2012, 102-103.
Wei W.I., Nasopharyngeal (Invited Lecture), Tri-Society Head and Neck Oncology Meeting, Singapore, 1 - 3 September 2011. 2011.
Wei W.I., Nasopharyngeal cancer: early diagnosis and salvage surgery (Invited Lecture), AAO-HNSF Annual Meeting 2011, San Francisco, U.S.A., 11 - 14 September 2011. 2011.
Wei W.I., Nasopharyngeal carcinoma-diagnoses and surgical treatment, The 18th Certificate Course in ENT Diseases for Nurses, Tung Wah Hospital, Hong Kong, 26 March 2012. 2012.
Wei W.I., Nasopharyngectomy: how I do it (Invited Lecture), Tri-Society Head and Neck Oncology Meeting, Singapore, 1-3 September 2011. 2011.
Wei W.I., National Delegate, Hong Kong Representative (1987 - present), Asian Federation of Laryngectomees Association. 2011.
Wei W.I., Panelist: Challenging Cases and Advanced Concepts – TORS , World Robotic SymWorld Robotic Transoral (TORS) Symposium, Miami, USA, 27-28 July 2011. 2011.
Wei W.I., Panelist: Managing Risk , The 22nd Annual North American Skull Base Society Meeting, Las Vegas, USA, 17-19 February 2012. 2012.
Wei W.I., Panelist: Skull Base Jeopardy Team #2, The 22nd Annual North American Skull Base Society Meeting, Las Vegas, USA, 17-19 February 2012. 2012.
Wei W.I., Panelist: Sponsored Symposium #7: International Federation of Head and Neck Oncologic Societies – Complex Issues in Cancer of the Oral Cavity, The 3rd World Congress of the International Academy of Oral Oncology, Singapore, 14-17 July 2011. 2011.
Wei W.I., Panelist: Surgical Dilemma, 2012 Annual Meeting and International Conference of Taiwan Head and Neck Society, Changhua, Taiwan, 9-10 June 2012. 2012.
Wei W.I., Parotid neoplasms (Invited Lecture), George L. Adams Memorial Lectureship, Minnesota, U.S.A., 8 August 2011. 2011.
Wei W.I., Pharyngo-laryngo-esopharygectomy: our experience, Head and Neck Course 2012, Theme: Cancer of the Larynx and Hypopharynx, Queen Mary Hospital, Hong Kong, 7-8 June 2012. 2012.
Wei W.I., Posterior tibial and maxillary swing dissection (Invited Lecture), George L. Adams Memorial Lectureship, Minnesota, U.S.A., 8 August 2011. 2011.
Wei W.I., President (April 2008 - present), Hong Kong Voice Foundation. 2011.
Wei W.I., Professional Advisor (1 February 1996 - present), The Hong Kong Society for Rehabilitation. 2011.
Wei W.I., QOL considerations and evidence-based management of N0 neck (Invited Lecture), Tri-Society Head and Neck Oncology Meeting,- Singapore, 1 - 3 September 2011. 2011.
Wei W.I., Representative (March 2005 – present), Hong Kong Society of Otorhinolaryngology, Head and Neck Surgery, International Federation of Oto-rhino-laryngological Societies. 2011.
Wei W.I., Robotic nasopharyngectomy (Invited Lecture), The 22nd Annual North American Skull Base Society Meeting, Las Vegas, U.S.A., 17 - 19 February 2012. 2012.
Wei W.I., Salvage surgery for recurrent nasopharyngeal cancer - from scalpel to robot (Invited Lecture), George L. Adams Memorial Lectureship, Minnesota, U.S.A., 8 August 2011. 2011.
Wei W.I., Salvage surgery for recurrent nasopharyngeal carcinoma: endoscope, robot or maxillary swing? (Invited Lecture), 2011 Annual Meeting and International Conference of Taiwan Head and Neck Society Kiaoshiung, Taiwan, 9 -10 July 2011. 2011.
Wei W.I., Surgery for malignant oral lesions (Course Director), Head and Neck Course 2011, Theme: Common Intraoral Pathologies, Queen Mary Hospital, Hong Kong, 25 - 26 August 2011. 2011.
Wei W.I., Surgery for malignant oral lesions, Head & Neck Course 2011, Theme: Common Intraoral Queen Mary Hospital, Hong Kong, 25-26 August 2011. 2011.
Wei W.I., Surgery for recurrent head and neck cancer (Invited Lecture), The 2nd International ORL Forum Shanghai Jiao Tong University, Shanghai, China, 6 - 7 October 2011. 2011.
Wei W.I., TORS for Recurrent Nasopharyngeal Carcinoma: The Hong Kong Experience, Challenging Cases and Advanced Concepts – TORS, World Robotic SymWorld Robotic Transoral (TORS) Symposium Miami, U.S.A. (invited), 27-28 July 2011. 2011.
Wei W.I., 榮譽顧問 (September 2008 – present), 青島市癌症康復協會 喉癌康復組. 2011.
Wei W.I., 第三屆中華普通外科雜誌編輯會編輯委員 (June 2006 – present), «中華普通外科雜誌». 2011.
Wei W.I., 第八屆編委 (November 2005 – present), «中華耳鼻咽喉頭頸外科雜誌». 2011.
Wong B.Y.H., Hui T., Lee S.L., Ho W.K. and Wei W.I., Stridor in Asian Infants: assessment and treatment, ISRN Otolaryngology. 2011, 2012.


Researcher : Wo YH

List of Research Outputs

Yau W.L., Pang R.W.C., Lee K.W., Lam C.S.C., Wo Y.H., Ng L., Chan J.Y.K., Chow A.K.M., Ng K.T.P., Man K. and Poon R.T.P., Overexpression of miR106b promotes metastasis in hepatocellular carcinoma by activating epithelial mesenchymal transition process, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.


Researcher : Wong ACC

List of Research Outputs

Wong A.C.C., Invited Chairman: "Vascular Emergencies", Hong Kong Surgical Forum - Winter, The University of Hong Kong, Hong Kong, 14 January 2012. 2012.
Wong A.C.C., Top myths in arteriovenous access, Hong Kong Surgical Forum, Hong Kong, 14 January 2012. 2012.


Researcher : Wong BYH

List of Research Outputs

Wong B.Y.H., Hui T., Lee S.L., Ho W.K. and Wei W.I., Stridor in Asian Infants: assessment and treatment, ISRN Otolaryngology. 2011, 2012.


Researcher : Wong CL

List of Research Outputs

Cheung P.F.Y., Yip C.W., Wong C.L., Cheng C.K.C., Wong Y.L. and Cheung S.T., Characterization of GEP-expressing cells in human primary hepatocellular carcinoma (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Cheung P.F.Y., Cheng C.K.C., Wong C.L., Ho J.C.Y., Yip C.W., Lui V.C.H., Cheung A.N.Y., Fan S.T. and Cheung S.T., Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells, PLoS One. 2011, 6(12): e28246.
Lam C.Y., Yip C.W., Poon T.C.W., Cheng C.K.C., Ng E.W.Y., Wong C.L., Cheung P.F.Y., Lai P.B.S., Ng I.O.L., Fan S.T. and Cheung S.T., Identification and characterization of tropomyosin 3 associated with granulin-epithelin precursor in human hepatocellular carcinoma, PLoS One. 2012, 7(7): e40324.
Wong C.L., Cheung P.F.Y. and Cheung S.T., Combined GEP targeted therapy and chemo-therapy eradicated human HCC in orthotopic mouse model (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Wong C.L., The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011, Young Investigator Award (Combined GEP targeted therapy and chemo-therapy eradicated human HCC in orthotopic mouse model). 2011.


Researcher : Wong CWS

List of Research Outputs

Wong K.W., Wong C.W.S., Chiang S.C., Tsang C.F., Li S.K., Chiu Y., Wong M.H., Fu K.K.F. and Ho K.L., A local survey on skeletal related complications in patients with carcinoma of prostate having hormonal therapy (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S8-S9.


Researcher : Wong HN

List of Research Outputs

Kwong A., Mang O.W., Wong H.N., Chau W.W., Law S.C. and Hong Kong Breast Cancer Research Group , Breast cancer in Hong Kong, Southern China: the first population-based analysis of epidemiological characteristics, stage-specific, cancer-specific, and disease-free survival in breast cancer patients: 1997-2001, Annals of Surgical Oncology. 2011, 18(11): 3072-3078.


Researcher : Wong J

Project Title:Thoracoscopic cardiomyotomy for achalasia
Investigator(s):Wong J, Law SYK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:01/1994


Project Title:Randomised prospective trial comparing the use of neck drain after oesophagectomy with cervical anastomosis
Investigator(s):Wong J, Law SYK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:01/1994


Project Title:Prospective study of the use of chemoradiotherapy in the treatment of advanced carcinoma of the oesophagus not suitable for resection
Investigator(s):Wong J, Law SYK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:01/1995


Project Title:Randomised prospective trial investigating the effect of preoperative chemo-radiation for resectable carcinoma of the oesophagus
Investigator(s):Wong J, Law SYK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:01/1995


Project Title:Retrospective and prospective study on the use of chemotherapy and chemoradiotherapy in the treatment of recurrent disease after oesophagectomy for cancer
Investigator(s):Wong J, Law SYK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:01/1995


Project Title:Thoracoscopic oesophagectomy for carcinoma of the oesophagus
Investigator(s):Wong J, Law SYK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:04/1996


Project Title:The use of endoscopic ultrasound in staging of esophageal cancer
Investigator(s):Wong J, Chu KM, Law SYK
Department:Surgery
Source(s) of Funding:Other Funding Scheme
Start Date:07/1996


List of Research Outputs

Chan S.C., Fan S.T. and Wong J., Recurrent pyogenic cholangitis, In: Jarnagin W.R. (ed.), Blumgart’s Surgery of the Liver, Biliary Tract, and Pancreas, 5th edition. Philadelphia, Elsevier Saunders, 2012, 1: 680-696.
Fan S.T., Yang Z., Ho D.W.Y., Ng N.P., Yu W.C. and Wong J., Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study, Annals of Surgery. 2011, 254(4): 569-576.


Researcher : Wong KF

Project Title:Targeting cadherin-17 for treatment of hepatocellular carcinoma by monoclonal antibody
Investigator(s):Wong KF, Poon RTP, Luk JMC
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:10/2009


List of Research Outputs

Ivanovska I., Zhang C., Liu A.M.L., Wong K.F., Lee N.P.Y., Lewis P., Philippar U., Bansal D., Buser C., Scott M., Mao M., Poon R.T.P., Fan S.T., Cleary M.A., Luk J.M.C. and Dai H., Gene signatures derived from a c-MET-driven liver cancer mouse model predict survival of patients with hepatocellular carcinoma, PLoS One. 2011, 6(9): e24582.
Sung W.K., Zheng H., Li S., Chen R., Liu X., Li Y., Lee N.P.Y., Lee W.H., Wong K.F., Liu A.M.L., Poon R.T.P., Fan S.T., Chan K.L. and Luk J.M.C., Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma, Nature Genetics. 2012, 44(7): 765-769.


Researcher : Wong KH

List of Research Outputs

Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., Extra Free Paper Session: What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer? (Abstract), Annual Scientific Meeting 2011, The College of Surgeons of Hong Kong and Macau Surgical Association, Hong Kong, 17 - 18 September 2011.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, Session on "ISDS Free Papers, Esophagus 1: Malignant", (Abstract), The International Surgical Week 2011, Yokohama, Japan, 28 August - 1 September 2011.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer?, Surgical Practice. 2011, 15(Suppl 2): B7.
Tong D.K.H., Law S.Y.K., Kwong D.L.W., Chan S.Y. and Wong K.H., What is the appropriate timing for surgery after neoadjuvant chemoradiation for esophageal cancer, World Journal of Surgery. 2011, 35(Suppl 1): S172.


Researcher : Wong KKY

Project Title:Gene polymorphism in the Sonic Hedgehog, Notch and Wnt signalling pathways in patients with keloid
Investigator(s):Wong KKY
Department:Surgery
Source(s) of Funding:Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme
Start Date:06/2006


Project Title:The use of encapsulated gold-porphyrin nanoparticles as a novel treatment for neuroblastoma
Investigator(s):Wong KKY, Lee PY
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:11/2009


Project Title:Development of a novel anti-bacterial suture with pro-healing properties using silver nanoparticles
Investigator(s):Wong KKY, Lee PY, Liu X
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:09/2010
Completion Date:02/2012


Project Title:Development of minimally invasive surgery for children in centres in rural China
Investigator(s):Wong KKY, Tam PKH
Department:Surgery
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2010


Project Title:The European Summit for Clinical Nanomedicine 2012 Nanomedicine Meets Regenerative Medicine: Does the Marriage have a Silver Lining?
Investigator(s):Wong KKY
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2012
Completion Date:05/2012


List of Research Outputs

Hao W., Chan I.H.Y., Liu X., Tang P.M.Y., Tam P.K.H. and Wong K.K.Y., Early post-operative interleukin-6 and tumour necrosis factor-α levels after single-port laparoscopic varicocelectomy in children, Pediatric Surgery International. 2012, 28(3): 281-286.
Huang J.S., Chung H.Y., Chan I.H.Y., Tao Q., Wong K.K.Y. and Tam P.K.H., Early outcomes of thoracoscopic repair of congenital diaphragmatic hernia (CDH): two centres' experience, IPEG's 21st Annual Congress for Endosurgery in Children, San Diego, U.S.A., 6 - 10 March 2012.
Huang J.S., Tao J.F., Chen K., Dai K.L., Tao Q., Chan I.H.Y., Chung H.Y., Lan L.C.L., Tam P.K.H. and Wong K.K.Y., Thoracoscopic repair of oesophageal atresia: experience of 33 patients from two tertiary referral centres, The 45th Annual Meeting of the Pacific Association of Pediatric Surgeons, Shanghai, China, 3 - 7 June 2012.
Kwan K.H.L., Liu X., Yeung K.W.K., Ho C.M., To M.K.T. and Wong K.K.Y., Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing, Nanomedicine: Nanotechnology, Biology and Medicine. 2011, 7(4): 497-504.
Lee P.Y., Zhang R., Li V., Liu X., Sun R.W.Y., Che C.M. and Wong K.K.Y., Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation, International Journal of Nanomedicine. 2012, 7: 731-737.
Leung J.L., Chung H.Y., Lan L.C.L., Wong K.K.Y. and Tam P.K.H., Management of tracheobronchial obstruction in infants using metallic stents: long-term outcome, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3 - 7 June 2012.
Leung J.L., Chung H.Y., Chan I.H.Y., Wong R.M.S., Chan A.W.S., Tam P.K.H. and Wong K.K.Y., The use of omega-3-fatty acid for short bowel syndrome patients accelerates reversal of cholestasis, The 45th Annual Meeting of Pacific Association of Pediatric Surgeons, Shanghai, China, 3-7 June 2012.
Liu X., Wong K.K.Y., Lui V.C.H., Chen Y., Ngan E.S.W., Garcia-Barcelo M.M. and Tam P.K.H., 香港大學小兒外科實驗室見聞 , 香港大學小兒外科實驗室見聞, 中華小兒外科雜誌. 中華小兒外科雜誌, 2011, 32(11): 29-34.
Ngan E.S.W., Garcia-Barcelo M.M., Yip B.H.K., Poon P.C., Lau C.S.T., Kwok K.M., Sat E.W.Y., Sham M.H., Wong K.K.Y., Wainwright B.J., Cherny S.S., Hui C.C., Sham P.C., Lui V.C.H. and Tam P.K.H., Hedgehog/Notch-induced premature gliogenesis represents a new disease mechanism for Hirschsprung’s disease in mice and humans, Journal of Clinical Investigation. 2011, 121(9): 3467-3478.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.
Tang S.M., Cheng G., So M.T., Yip B.H.K., Miao X., Wong E.H.M., Ngan E.S.W., Lui V.C.H., Song Y., Chan D., Cheung K.M.C., Yuan Z.W., Lei L., Chung H.Y., Liu X., Wong K.K.Y., Marshall C.R., Scherer S., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Genome-wide copy number analysis uncovers a new HSCR gene: NRG3, PLoS Genetics. 2012, 8(5): e1002687.
Tang S.M., Ngan E.S.W., Tang W.K., So M.T., Cheng G., Miao X., Leon Y.Y., Leung M.C., Hui K.-.J. .W.S., Lui V.C.H., Chen Y., Chan I.H.Y., Chung P.H.Y., Liu X., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Mutations in the NRG1 gene are associated with Hirschsprung disease, Human Genetics. 2012, 131(1): 67-76.
To M.K.T., Yeung K.W.K., Wong K.K.Y., Liu X. and Kwan K.H.L., The Modulating Action of Silver Nanoparticles on Collagen Deposition in Producing Scarless Wound Healing, Australia Orthopaedic Association / New Zealand Orthopaedic Association Combined Annual Scientific Meeting. 2011.
To M.K.T., Wong K.K.Y., Yeung K.W.K., Kwan K.H.L. and Liu X., The Modulating Action of Silver Nanoparticles on Collagen Deposition in Producing Scarless Wound Healing, Tissue Engineering & Regenerative Medicine International Society. 2011.
Wang B., Feng Q., Mao J.X., Liu L. and Wong K.K.Y., Early experience with laparoscopic excision of choledochal cysts in 41 children, The 45th Annual Meeting of the Pacific Association of Pediatric Surgeons, Shanghai, China, 3 - 7 June 2012.
Wang B., Mao J.X., Feng Q., Wang J.Y., Liu L. and Wong K.K.Y., Mentoring complex laparoscopic surgery in children: lessons learnt from laparoscopic choledochal cyst excision, The International Pediatric Endosurgery Group's 21st Annual Congress for Endosurgery in Children, San Diego, U.S.A., 6 - 10 March 2012.
Wong K.K.Y., Associate Editor, Nanomedicine: Nanotechnology, Biology and Medicine. 2011.
Wong K.K.Y., Basic laparoscopy: cholecystectomy (Invited Lecture), Pediatric Minimally Invasive Surgery: Showcase in Asia (Part 1: Biliary and Solid Organ), Hong Kong, 15 December 2011. 2011.
Wong K.K.Y. and Tam P.K.H., Biliary atresia Kasai or liver transplantation? (Invited Lecture), International Surgical Week 2011, Pacifico Yokohama, Japan, 28 August - 1 September 2011. 2011.
Wong K.K.Y., Wu X.Z., Chan I.H.Y. and Tam P.K.H., Evaluation of defecative function 5 years or longer after laparoscopic-assisted pull-through for imperforate anus, Journal of Pediatric Surgery. 2011, 46(12): 2313-2315.
Wong K.K.Y., Li L., Li S.L. and Tam P.K.H., Experience of setting up laparoscopic workshops in China: a 4-year review, The International Pediatric Endosurgery Group's 21st Annual Congress for Endosurgery in Children, San Diego, U.S.A., 6 - 10 March 2012.
Wong K.K.Y., Neonatal surgery in the 21st century - the Hong Kong experience, 21世紀的新生兒外科 - 香港大學的經驗, In: 劉磊、夏慧敏 (eds.), Neonatal Surgery. 新生兒外科, People's Military Medical Press, 2011.
Wong K.K.Y. and Tam P.K.H., Omphalomesenteric duct remnants, In: Puri P. (ed.), Newborn Surgery, 3rd edition. London, Hodder Arnold, 2011.
Wong K.K.Y., Regenerative medicine meets nanomedicine: does the marriage have a silver lining?, European Summit for Clinical Nanomedicine, Basel, Switzerland, 7 - 9 May 2012.
Wong K.K.Y., Reviewer, Expert Opinion on Therapeutic Targets. 2012.
Wong K.K.Y., Reviewer, Journal of Magnetic Resonance Imaging. 2011.
Wong K.K.Y., Reviewer, Journal of Nanomedicine & Nanotechnology. 2012.
Wong K.K.Y., Reviewer, Journal of Nanoparticle Research. 2012.
Wong K.K.Y., Reviewer, Journal of Paediatrics & Child Health. 2012.
Wong K.K.Y., Reviewer, Journal of Pediatric Surgery. 2011.
Wong K.K.Y., 小兒胸膛鏡發展現狀 (Invited Lecture), The 10th Laparoscopic Workshop in China (collaborated with Jiangxi Provincial Children's Hospital), Nanchang, China, 18 - 21 May 2012. 2012.
Wong K.K.Y. and Yip P.K.F., 割包皮, 明報周刊 2011/09/10 : Ming Junior Feature. 2011, 2235: 92-93.
Wong K.K.Y., 第三屆編輯委員會委員 (June 2012-May 2015), 臨床小兒外科雜誌. 2012.
Wong K.K.Y., 膽導閉鎖-Kasai手術的應用和改良 (Invited Lecture), 2012中國小兒外科臨床論壇, 中國長沙, 6 - 8 June 2012, 2012.
Wong K.K.Y., 小兒胸膛鏡發展現狀 (Invited Lecture), 首届中华小儿微创外科学组学术研讨会, Xian, China, 4 - 5 May 2012, 2012.


Researcher : Wong STS

Project Title:Identifying the differential microRNA signatures in squamous cell carcinoma of oral tongue
Investigator(s):Wong STS, Wei WI
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2009


Project Title:Revealing the role of human telomerase reverse transcriptase gene methylation in oral tongue squamous cell carcinoma
Investigator(s):Wong STS
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:AACR annual meeting The role of tumor suppressing microRNA let-7 in undifferentiated nasopharyngeal carcinoma
Investigator(s):Wong STS
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:04/2012


List of Research Outputs

Chan Y.W., To V.S.H., Wong S.T.S. and Wei W.I., Quality of dying in head and neck cancer patients: the role of surgical palliation, European Archives of Oto-Rhin-Laryngology. 2012, Epub on 5 June 2012.
Gao W., Chan Y.W., Wei W.I. and Wong S.T.S., Anti-Cancer effects of curcumin on head and neck cancer, Anticancer Agents in Medical Chemistry. 2012, Epub on 2 May 2012.
Gao W., Li J.Z., Ho W.K., Chan Y.W. and Wong S.T.S., Biomarkers for use in monitoring responses of nasopharyngeal carcinoma cells to Ionizing radiation, Sensors. 2012, 12(7): 8832-8846.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in human malignant gliomas: a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide, The Society for NeuroOncology. 2011.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in malignant gliomas - a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide (P4HB) (Abstract), Neuro-oncology. 2011, 13(3): 111.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Identifying molecular candidates associated with acquired temozolomide resistance in human malignant glioma - a proteomics approach., The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Sun S., Pu J.K.S., Leung G.K.K. and Wong S.T.S., Prolyl 4-hydroxylase, Beta polypeptide (P4HB) as a Potential Target for Combating Temozolomide Resistance in Human Malignant Glioma, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Sun S., Wong S.T.S., Zhang X., Pu J.K.S., Lee N.P.Y., Day P.J., Ng K.B., Lui W.M. and Leung G.K.K., Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines , Journal of Neuro-oncology. 2012, 107(1): 89-100.
To V.S.H. and Wong S.T.S., Structural disturbance and reconstruction of glossectomy patients, In: Katô H. and Shimizu T. (eds.), Tongue: Anatomy, Kinematics and Diseases (Human Anatomy and Physiology). Hauppauge, New York, Nova Science, 2012, 73-88.
Tsang R.K.Y., Tang W.Y., Gao W., Ho W.K., Chan Y.W., Wei W.I. and Wong S.T.S., Curcumin inhibits tongue carcinoma cells migration and invasion through downregulation of matrix metallopeptidase 10, Cancer Investigation. 2012, 30(7): 503-512.
Tsang R.K.Y., Gao W. and Wong S.T.S., Surgical treatment of the squamous cell carcinoma of the tongue and the effect on speech and swallowing, In: Kato H. and Shimizu T. (eds.), Tongue: Anatomy, Kinematics and Diseases (Human Anatomy and Physiology). Hauppauge, New York, Nova Science, 2012, 1-16.
Wong S.T.S., Gao W., Li Z., Chan Y.W. and Ho W.K., Epigenetic dysregulation in laryngeal squamous cell carcinoma, Journal of Oncology. 2012, 2012: 739461.
Wong S.T.S., Micro RNA dysregulation in head and neck cancer, Head & Neck Course 2011, Hong Kong, 25 - 26 August 2011. 2012.
Wong S.T.S., Gao W., Ho W.K., Chan Y.W. and Tsang R.K.Y., MicroRNA dysregulation in squamous cell carcinoma of head and neck, In: Li X. (ed.), Squamous Cell Carcinoma. Rijeka, Croatia, Intech, 2011, 255-280.
Zhang X., Sun S., Pu J.K.S., Tsang C.O.A., Lee D., Lui W.M., Wong S.T.S., Leung G.K.K. and Man V.O.Y., Long non-coding RNA expression profiles predict clinical phenotypes in glioma, Neurobiology of Disease. 2012, 48(1): 1-8.


Researcher : Wong TS

Project Title:Identifying the differential microRNA signatures in squamous cell carcinoma of oral tongue
Investigator(s):Wong STS, Wei WI
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2009


Project Title:Revealing the role of human telomerase reverse transcriptase gene methylation in oral tongue squamous cell carcinoma
Investigator(s):Wong STS
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:AACR annual meeting The role of tumor suppressing microRNA let-7 in undifferentiated nasopharyngeal carcinoma
Investigator(s):Wong STS
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:04/2012


List of Research Outputs



Researcher : Wong YL

List of Research Outputs

Cheung P.F.Y., Yip C.W., Wong C.L., Cheng C.K.C., Wong Y.L. and Cheung S.T., Characterization of GEP-expressing cells in human primary hepatocellular carcinoma (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.


Researcher : Yang S

List of Research Outputs

Wang X., Zhang W., Lui E.L.H., Zhu Y., Lu P., Yu X., Sun J., Yang S., Poon R.T.P. and Fan S.T., Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma, International Journal of Cancer. 2011, 131(3): E163-172.


Researcher : Yang Z

List of Research Outputs

Fan S.T., Yang Z., Ho D.W.Y., Ng N.P., Yu W.C. and Wong J., Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study, Annals of Surgery. 2011, 254(4): 569-576.
Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Lau C.K., Yang Z. and Fan S.T., Role of stem cells in normal liver and cancer, Anti-Cancer Agents in Medicinal Chemistry. 2011, 11(6): 522-528.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.


Researcher : Yau TCC

Project Title:The Role of Serial Changes in Circulating Angiogenic Markers in Predicting the Clinical Outcome of Advanced Hepatocellular Carcinoma (HCC) Patients on Sorafenib
Investigator(s):Yau TCC, Fan ST, Poon RTP, Pang RWC
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:Asia Oncology Summit 2012 The Combination of Bevacizumab and Erlotinib in the Treatment of Advanced Hepatocellular Carcinoma Patients with Sorafenib-refractory Disease: Results of a Pilot Phase II study
Investigator(s):Yau TCC
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2012
Completion Date:04/2012


Project Title:A Pilot Study to Evaluate the Prophylactic Effects of Telbivudine for Prevention of Hepatitis B Reactivation in HBsAg Positive Patients Receiving Sorafenib Treatment for Advanced Hepatocellular Carcinoma
Investigator(s):Yau TCC, Poon RTP
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:06/2012


List of Research Outputs

Ali R., Toh H.C., Chia W.K. and Yau T.C.C., The utility of Aspirin in Dukes C and High Risk Dukes B Colorectal cancer--the ASCOLT study: study protocol for a randomized controlled trial, Trials. 2011, 12: 261.
Chan K.Y., Chan M.L., Yau T.C.C., Li B.C., Cheng B.H. and Sham M.M., Quality of life in Chinese patients with advanced gynecological cancers in palliative phase and its clinical correlates: a prospective, cross-sectional study, Journal of Palliative Care. 2012, 28(4): Epub ahead of print.
Cheung T.T., Poon R.T.P., Yau T.C.C., Tsang D.S., Lo C.M. and Fan S.T., High-intensity focused ultrasound as a treatment for colorectal liver metastasis in difficult position (Letter to the Editor), International Journal of Colorectal Disease. 2011, Epub on 2011-08-13.
Cheung T.T., Chu F.S., Jenkins C.R., Tsang D.S., Chok K.S.H., Chan A.C.Y., Yau T.C.C., Chan S.C., Poon R.T.P., Lo C.M. and Fan S.T., Tolerance of high-intensity focused ultrasound ablation in patients with hepatocellular carcinoma, World Journal of Surgery. 2012, Epub on 2012-06-15.
Chiu J., Tang Y.F., Yao T.J., Wong A., Wong H., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Fan S.T., Poon R.T.P. and Yau T.C.C., The use of single-agent sorafenib in the treatment of advanced hepatocellular carcinoma patients with underlying Child-Pugh B liver cirrhosis: A retrospective analysis of efficacy, safety, and survival benefits, Cancer. 2012, Epub on 2012-04-19.
Chiu J.W., Pang R.W.C., Poon R.T.P. and Yau T.C.C., Systemic management of advanced hepatocellular carcinoma patients: the role of multi-targeted anti-angiogenic inhibitors, In: Lau J.W.Y. (ed.), Hepatocellular Carcinoma - Clinical Research. Shanghai, InTech, 2011, 309-320.
Cohen M.J., Levy I., Barak O., Bloom A.I., Fernández Ruiz M., Di Maio M., Perrone F., Poon R.T.P., Shouval D., Yau T.C.C. and Shibolet O., Trans-arterial chemo-embolization (TACE) is safe and efficient for elderly patients with advanced hepatocellular carcinoma (HCC): Results from an international meta-database, Journal of Hepatology. 2012, 54 (Suppl 1): not known.
Fan S.T., Yau T.C.C. and Poon R.T.P., Comprehensive management of hepatocellular carcinoma, Chinese Journal of Digestive Surgery. 2011, 10(4): 241-246.
Fan S.T., Yau T.C.C. and Poon R.T.P., 肝癌的綜合治療, 中華消化外科雜誌, 2011, 10: 241-246.
Wong H., Lau S., Leung R.C.Y., Chiu J., Cheung P., Wong T.T., Liang R., Epstein R.J. and Yau T.C.C., Coexisting ductal carcinoma in situ independently predicts lower tumor aggressiveness in node-positive luminal breast cancer, Medical Oncology. 2011, Epub on 2011-10-08.
Wong H., Chan P. and Yau T.C.C., Colon cancer in a patient with underlying aplastic anemia: a clinical challenge, World Journal of Clinical Oncology. 2012, 3(2): 29-31.
Wong H., Leung R., Kwong A., Chiu J., Liang R., Swanton C. and Yau T.C.C., Integrating molecular mechanisms and clinical evidence in the management of Trastuzumab resistant or refractory HER-2+ metastatic breast cancer, Oncologist. 2011, 16(11): 1535-1546.
Wong H., Wong K.P., Yau T.C.C., Tang V., Leung R., Chiu J. and Lang B.H.H., Is there a role for unstimulated thyroglobulin velocity in predicting recurrence in papillary thyroid carcinoma patients with detectable thyroglobulin after radioiodine ablation?, Annals of Surgical Oncology. 2012, Epub ahead of print.
Wong H., Lau S., Cheung P., Leung R., Chiu J., Wong T.T., Liang R., Epstein R.J. and Yau T.C.C., Ki67 proliferation index in invasive lobular carcinoma of the breast: clinicopathologic correlation and prognostic significance, European Journal of Cancer. 2012, 48(Suppl 1): S136.
Wong H. and Yau T.C.C., Review: metronomic chemotherapy for advanced cutaneous angiosarcoma, Clinical Advances in Hematology and Oncology. 2011, 9(6): 504-506.
Wong H. and Yau T.C.C., Targeted therapy in the management of advanced gastric cancer: are we making progress in the era of personalized medicine?, Oncologist. 2012, 17(3): 346-358.
Wong H., Tang Y.F., Yao T., Chiu J., Leung R.C.Y., Chan P., Cheung T.T., Chan A.C.Y., Pang R.W.C., Poon R.T.P., Fan S.T. and Yau T.C.C., The outcomes and safety of single-agent sorafenib in the treatment of elderly patients with advanced hepatocellular carcinoma (HCC), Oncologist. 2011, 16(12): 1721-1728.
Yau T.C.C., Cheng P.N., Chan P., Chan W.Y.L., Chen L., Yuen J., Pang R.W.C., Fan S.T. and Poon R.T.P., A phase 1 dose-escalating study of pegylated recombinant human arginase 1 (Peg-rhArg1) in patients with advanced hepatocellular carcinoma, Investigational New Drugs. 2012, Epub on 2012-03-17.
Yau T.C.C., Sukeepaisarnjaroen W., Chao Y., Yen C.J., Lausoontornsiri W., Chen P.J., Sanpajit T., Lencioni R., Camp A., Kallender H., Ottesen L.H. and Poon R.T.P., A phase I/II study of Foretinib, an oral multikinase inhibitor targeting MET, RON, AXL, TIE-2 and VEGFR in advanced hepatocellular carcinoma (HCC), Journal of Clinical Oncology. 2011, 29(Suppl): abstr 4082.
Yau T.C.C., Associate Editor, Frontiers in Genitourinary Oncology. 2011.
Yau T.C.C., Associate Editor, Journal of Medical Case Report. 2011.
Yau T.C.C., Best Abstract Award (Abstract title not provided), Chinese Society of Clinical Oncology, Round Asian Oncology Forum, Shanghai, China, 2011. 2011.
Yau T.C.C., Chairman, GSK Breast Cancer Symposium: Correlation of Molecular Effects and the Response in Anti-HER2 Therapies in HER2+ Metastatic Breast Cancer, Hong Kong, August 2011. 2011.
Yau T.C.C., Chairman, Macau Oncology Association Summer Symposium, August 2011. 2011.
Yau T.C.C., Chairman, Poster Session of the 18th Medical Research Conference organised by Department of Medicine, The University of Hong Kong, January 2012. 2012.
Yau T.C.C., Chairman, The 18th Hong Kong International Cancer Congress Gastrointestinal Cancer Symposium, Hong Kong, November 2011. 2011.
Yau T.C.C., Clinical utility of genomic profiling in making adjuvant treatment decisions in node-positive early breast cancer, Hong Kong Society of Breast Surgeons and Hong Kong Breast Cancer Foundation CME Lecture, Hong Kong. 2012.
Yau T.C.C., Wong H., Lau S., Leung R., Chiu J., Wong T.T., Liang R., Epstein R.J. and Cheung P., Comparison of clinicopathologic features of invasive lobular carcinoma of the breast with or without associated lobular carcinoma in-situ, European Journal of Cancer. 2012, 48(Suppl 1): S179.
Yau T.C.C., Editorial Board Member, ISRN Haematology. 2011.
Yau T.C.C., Editorial Board Member, Journal of Medical Cases. 2011.
Yau T.C.C., Editorial Board Member, The Open Drug Resistance Journal. 2011.
Yau T.C.C., Editorial Board Member, World Journal of Clinical Oncology. 2011.
Yau T.C.C., Editorial Board Member, World Journal of Gastrointestinal Pharmacology and Therapeutics. 2011.
Yau T.C.C., Editorial Board Member, World Journal of Hepatology. 2011.
Yau T.C.C., GIDEON (Global investigation of therapeutic decisions in hepatocellular carcinoma and of its treatment with sorafenib) second interim analysis in >1500 patients: clinical findings in patients with liver dysfunction, The 4th Singapore Society of Oncology & Chapter of Medical Oncologists Review Course Bayer Tea Symposium, Singapore, February 2012. 2012.
Yau T.C.C., Hepatobiliary research highlight and future direction in Hong Kong, United States National Cancer Institue (NCI) Hepatobiliary Task Force Meeting, Chicago, U.S.A., June 2012. 2012.
Yau T.C.C., Invited Faculty, Lancet Oncology Asia Oncology Summit Treatment Guides for Asian Patients with Colorectal Cancer Consensus Meeting, Singapore, April 2012. 2012.
Yau T.C.C., Invited Faculty, Novartis Emerging Market Neuroendocrine Tumour Roundtable Discussion, Singapore, July 2011. 2011.
Yau T.C.C., Management of refractory colorectal cancer: what is on the horizon?, The 18th Hong Kong International Cancer Congress, The University of Hong Kong, Hong Kong, 3 - 5 November 2011. 2011.
Yau T.C.C., Member, Novartis Emerging Market Neuroendocrine Tumour Advisory Board, Hong Kong. 2011.
Yau T.C.C., Member, Panel for Multidisciplinary Tumor Board: Case Reviews and Key Pad Questions, the 1st Asia Pacific Breast Cancer Summit, Singapore, February 2012. 2012.
Yau T.C.C., Member, SIR-Spheres Microspheres Advisory Board, Singapore. 2012.
Yau T.C.C., Metastatic colorectal cancer-facts (epidemiology & treatment standards, The 3rd Merck Serono Asian Oncology Summit, Hong Kong, May 2012. 2012.
Yau T.C.C., Optimizing treatment for metastatic renal cell carcinoma, Macau Oncology Association Summer Symposium. 2011.
Yau T.C.C., Outstanding Research Paper Award 2011 (Paper title not provided), Department of Surgery, The University of Hong Kong. 2012.
Yau T.C.C., Chen P.J., Chan P., Curtis C.M., Murphy P.S., Suttle A.B., Gauvin J., Hodge J.P., Dar M.M. and Poon R.T.P., Phase I dose-finding study of pazopanib in hepatocellular carcinoma: evaluation of early efficacy, pharmacokinetics, and pharmacodynamics, Clinical Cancer Research. 2011, 17(21): 6914-6923.
Yau T.C.C., Wong H., Chan P., Yao T., Pang R.W.C., Cheung T.T., Fan S.T. and Poon R.T.P., Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory disease, Investigational New Drugs. 2012, Epub on 2012-03-09.
Yau T.C.C., Practical applications of anti-angiogenic agents in systemic management of hepatocellular carcinoma, Department of Medicine Grand Round, Kwong Wah Hospital, Hong Kong, March 2012. 2012.
Yau T.C.C., Practical applications of anti-angiogenic therapy in unresectable hepatocellular carcinoma, The 4th Singapore Society of Oncology & Chapter of Medical Oncologists Review Course, Singaore, February 2012. 2012.
Yau T.C.C., Practical applications of targeted therapy in systemic management of hepatocellular carcinoma, Singapore Bayer Schering Round Table Symposium, February, 2012. 2012.
Yau T.C.C., Reviewer, Cancer. 2011.
Yau T.C.C., Reviewer, Cancer Therapy. 2011.
Yau T.C.C., Reviewer, Expert Review of Anticancer Therapy. 2011.
Yau T.C.C., Reviewer, Expert Review of Pharmacoeconomics & Outcomes Research. 2011.
Yau T.C.C., Reviewer, Future Oncology. 2011.
Yau T.C.C., Reviewer, Hepatology International. 2011.
Yau T.C.C., Reviewer, Journal of Cancer Therapy . 2011.
Yau T.C.C., Reviewer, Journal of Clinical Oncology. 2011.
Yau T.C.C., Reviewer, Journal of Experimental & Clinical Cancer Research . 2011.
Yau T.C.C., Reviewer, Medical Oncology. 2011.
Yau T.C.C., Reviewer, Mini-reviews in Medicinal Chemistry . 2011.
Yau T.C.C., Reviewer, Pharmaceuticals. 2011.
Yau T.C.C., Reviewer, World Journal of Surgical Oncology. 2011.
Yau T.C.C., Session Chairman, The 17th Hong Kong Medical Forum, Hong Kong, May 2012. 2012.
Yau T.C.C., Supervisor Award of Best Thesis Award (Thesis title not provided), Hong Kong College of Physicians. 2011.
Yau T.C.C., Systemic management of hepatocellular carcinoma and pancreatic cancers: medical oncologist perspectives, CME Lecture of Private Service and Department of Clinical Oncology, Queen Mary Hospital, Hong Kong. 2012.
Yau T.C.C., Systemic therapy of advanced hepatocellular carcinoma in 2011, Public Health Talk Organised by the Health Action, Hong Kong. 2011.
Yau T.C.C., Systemic therapy of advanced hepatocellular carcinoma in the era of personalized medicine: Asian perspective, Princess Margaret Hospital, University of Toronto, Toronto, Canada. 2012.
Yau T.C.C., Systemic therapy of advanced hepatocellular carcinoma: medical oncologist perspectives, Macau Peak Hospital. 2012.
Yau T.C.C., Systemic therapy of advanced hepatocellular carcinoma: are we making progress in the era of personalized medicine?, University College of London Cancer Institute, University of London, United Kingdom. 2012.
Yau T.C.C., The Asian perspectives in the management of K-Ras wild type advanced colorectal cancer: Bevacizumab or anti-EGFR therapy?, Round Asia Oncology Forum, Chinese Society of Clinical Oncology, Shanghai, China, August 2011. 2011.
Yau T.C.C., The introduction to the management of neuroendocrine tumours, Novartis Asia-Pacific Neuroendocrine Tumour School, Hong Kong. 2011.
Yau T.C.C., Yao T.J., Chan P., Wong H., Pang R.W.C., Fan S.T. and Poon R.T.P., The significance of early alpha-fetoprotein level changes in predicting clinical and survival benefits in advanced hepatocellular carcinoma patients receiving sorafenib, Oncologist. 2011, Epub on 2011-09-01.
Yau T.C.C., The systemic management of advanced hepatocellular carcinoma patients: are we making any progress in the era of personalised medicine?, Bit’s 1st Annual World Congress of Microbes, Beijing, China, 30 July - 1 August 2011. 2011.
Yau T.C.C., The use of Sorafenib in the mnagement of advanced hepatocellular carcinoma: benefit in elderly patients?, Bayer Schering Asia Gideon Virtual Meeting, Singapore, October 2011. 2011.


Researcher : Yau WL

List of Research Outputs

Geng W., Ng K.T.P., Sun K.W., Yau W.L., Liu X., Cheng Q., Poon R.T.P., Lo C.M., Man K. and Fan S.T., The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma, PLoS One. 2011, 6(11): e27362.
Yau W.L., Pang R.W.C., Lee K.W., Lam C.S.C., Wo Y.H., Ng L., Chan J.Y.K., Chow A.K.M., Ng K.T.P., Man K. and Poon R.T.P., Overexpression of miR106b promotes metastasis in hepatocellular carcinoma by activating epithelial mesenchymal transition process, The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.


Researcher : Yeung C

List of Research Outputs

Lamb J.R., Zhang C., Xie T., Wang K., Zhang B., Hao K., Chudin E., Fraser H.B., Millstein J., Ferguson M., Suver C., Ivanovska I., Scott M., Poon R.T.P., Fan S.T., Yeung C., Lee N.P.Y. and Luk J.M.C., Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting, PLoS One. 2011, 6(7): e20090.


Researcher : Yeung WH

List of Research Outputs

Shao Y., Li C., Ma Y.Y., Liu X., Ling C., Yeung W.H., Lee K.W., Fan S.T., Lo C.M. and Man K., The role of regulatory B cells during the progression of human hepatocellular carcinoma, Immunology 2012 Conference, Boston, Massachusetts, U.S.A., 4 - 8 May 2012. Journal of Immunology. 2012, 188(Suppl): 162.39.
Yeung W.H., Lee K.W., Geng W., Li C., Ng K.T.P., Lo C.M., Guan X., Poon R.T.P., Fan S.T. and Man K., M2 macrophages promotes tumor growth and invasion in hepatocellular carcinoma, The 18th Annual International Congress of the International Liver Transplantation Society, San Francisco, California, U.S.A., 16 - 19 May 2012.


Researcher : Yip CW

Project Title:Paracrine effects of granulin-epithelin precursor (GEP) in hepatocellular carcinoma
Investigator(s):Yip CW, Cheung ST
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:01/2012


List of Research Outputs

Cheung P.F.Y., Yip C.W., Wong C.L., Cheng C.K.C., Wong Y.L. and Cheung S.T., Characterization of GEP-expressing cells in human primary hepatocellular carcinoma (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Cheung P.F.Y., Cheng C.K.C., Wong C.L., Ho J.C.Y., Yip C.W., Lui V.C.H., Cheung A.N.Y., Fan S.T. and Cheung S.T., Granulin-epithelin precursor is an oncofetal protein defining hepatic cancer stem cells, PLoS One. 2011, 6(12): e28246.
Lam C.Y., Yip C.W., Poon T.C.W., Cheng C.K.C., Ng E.W.Y., Wong C.L., Cheung P.F.Y., Lai P.B.S., Ng I.O.L., Fan S.T. and Cheung S.T., Identification and characterization of tropomyosin 3 associated with granulin-epithelin precursor in human hepatocellular carcinoma, PLoS One. 2012, 7(7): e40324.
Yip C.W. and Cheung S.T., Characterization of granulin-epithelin precursor (GEP) binding properties on cell surface of hepatoma (Abstract), The 18th Hong Kong International Cancer Congress, Hong Kong, 3-5 November 2011.
Yip C.W. and Cheung S.T., Characterization of granulin-epithelin precursor (GEP) binding properties on cell surface of hepatoma , The 18th Hong Kong International Cancer Congress, Hong Kong, 3 - 5 November 2011.


Researcher : Yip PKF

List of Research Outputs

Wong K.K.Y. and Yip P.K.F., 割包皮, 明報周刊 2011/09/10 : Ming Junior Feature. 2011, 2235: 92-93.


Researcher : Yiu MK

List of Research Outputs

Chan C.K., Tsu H.L., Chu W.H., Kong C.K., Law I.C., Liu P.L. and Yiu M.K., Emphysematous pyelonephritis: an eight-year retrospective review across four hospitals in a single cluster (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S2.
Chan C.K., Ma W.K., Chu T.Y., To K.C. and Yiu M.K., Robot-assisted ureteral reimplantation in children with vesico-ureteral reflux (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S7-S8.
Ip C.H., Chu T.Y., To K.C., Yiu M.K. and Cheung F.K., Arteriovenous grafts for hemodialysis: a retrospective study from a local urologcial centre (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011 / Surgical Practice. 2012, 16(Suppl): S2.
Ng A.T.L., Fu K.K.F., Ho K.L. and Yiu M.K., PCNL trajectory: a novel concept to predict success in supine PCNL (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S9-S10.
Ng C.M., Ma W.K., To K.C. and Yiu M.K., The Chinese version of the pelvic pain and urgency / frequency symptom scale: a useful assessment tool for street-ketamine abusers with lower urinary tract symptoms, Hong Kong Medical Journal. 2012, 18(2): 123-130.
Tsang C.F., Fu K.K.F., Ng S.L., Cheung M.H., Ng A.T.L., Ho B.S.H., Ho K.L. and Yiu M.K., The relationship between renal stone excursion distance and body build during ESWL (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S6-S7.
Tsu H.L., Ma W.K., Lam S.H., Chan K.W., To K.C., To W.K., Ng T.K., Liu P.L. and Yiu M.K., Prevalence of antibiotic-resistant intestinal flora in patients undergoing transrectal ultrasonography-guided prostate biopsy (TRUS-Bx) and its implication for clinical practice: preliminary results (Abstract), The 17th Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 6 November 2011. Surgical Practice. 2012, 16(Suppl): S2-S3.
Yeung J.T.H., Ma J.K.F., Kwok K.K.M., Yung A.W.T., Cheng R.L.F., To K.C. and Yiu M.K., Ketamine-related urological complications: radiological features, Hong Kong Journal of Radiology. 2012, 15(1): 4-9.
Yip S.K.H., Yee C.H., Ng C.F., Lam N.Y., Ho K.L., Ma W.K., Li C.M., Hou S.M., Tam P.C., Yiu M.K. and Fan C.W., Robot-assisted radical prostatectomy in Hong Kong: a review of 235 cases, Journal of Endourology. 2012, 26(3): 258-263.
Yiu M.K., Endoscopic procedure for the urinary tract (Invited Lecture), Symposium on Advances in Endoscopy 2012 by Departments of Surgery & Medicine, The University of Hong Kong, Hong Kong, 24 March 2012. 2012.
Yiu M.K., Hong Kong experience (Invited Lecture), Asian Robotic Urological Symposium (ARUS) by the Intuitive Surgical Inc, Jeju, Korea, 28 November 2011. 2011.
Yiu M.K., Moderator - LUTS , World Chinese Urological Society Meeting on Urological Oncology in conjunction with the Annual Meeting of American Urological Association, Atlanta, USA, 19 May 2012. 2012.
Yiu M.K., Moderator of Live Surgery Demonostration - Men’s Health, Urology Symposium 2011 by Jockey Club Minimally Invasive Surgical Skills Centre, The Chinese University of Hong Kong, Hong Kong, 5 November 2011. 2011.
Yiu M.K., Principle and essentials of vascular access (Invited Lecture), Nursing Forum of Vascular Access for Renal Replacement Therapy – Achieving Optimal Vascular Access Outcomes by Nursing Service Department, HAHO and Renal Specialty Advisory Group, Hong Kong, 27 November 2011. 2011.
Yiu M.K., Reviewer, Hong Kong Medical Journal. 2011.
Yiu M.K., da Vinci prostatectomy: state of the art (Invited Lecture), The 6th Advances in Urological Nursing Workshop, Hong Kong, 8 June 2012. 2012.
Yiu M.K., 機械臂輔助前列腺腫瘤切除術 (Invited Lecture), 2011中國泌尿外科學學術論壇, 中國廣州, 2011年12月10日, 2011.


Researcher : Yiu WK

Project Title:Effects of testosterone and dehydroepiandrosterone on migration and adhesion in vascular smooth muscle cells
Investigator(s):Yiu WK, Cheng SWK, Cheuk LY
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:53rd ICA Annual World Congress Treating mycotic aortic aneurysm with endovascular stent graft repair
Investigator(s):Yiu WK
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2011
Completion Date:09/2011


List of Research Outputs

Chan Y.C., Ting A.C.W., Yiu W.K. and Cheng S.W.K., Successful emergency endovascular treatment of juxtarenal and infrarental mycotic aortic aneurysms in patients with small diameter aortae using Cook Zenith ESLE stentgrafts, World Journal of Emergency Medicine. 2012, 3(2): 146-149.
Cheng S.W.K., Qing K. and Yiu W.K., A morphologic study of chronic type B aortic dissections and aneurysms after thoracic endovascular stent grafting, The 26th Annual Meeting of the Western Vascular Society, Kauai, Hawaii, 17-20 September 2011.
Qing K., Yiu W.K. and Cheng S.W.K., A morphologic study of chronic type B aortic dissections and aneurysms after thoracic endovascular stent grafting, Journal of Vascular Surgery. 2012, 55(5): 1268-1276.
Yiu W.K., Current management of mycotic aortic aneurysms , Hong Kong Surgical Forum - Winter, The University of Hong Kong, Hong Kong, 14 January 2012. 2012.
Yiu W.K. and Cheng S.W.K., Endovascular repair for bleeding aortoenteric fistula is associated with lower perioperative mortality, 2011 Asian Chapter Congress of International Union of Angiology, Beijing, China, 20-22 October 2011.
Yiu W.K., Chan Y.C., Ting A.C.W. and Cheng S.W.K., Para-aortic lymphoma mimicking mycotic abdominal aortic aneurysm: case presentation & review of literature (Poster Presentation), The 12th Annual Congress of the Asian Society for Vascular Surgery (ASVS) and 6th Asian Venous Forum, Taipei, Taiwan, 29 September to 2 October 2011.
Yiu W.K. and Cheng S.W.K., Treating mycotic aortic aneurysms with endovascular stent graft repair (Oral Presentation), The 53rd Annual World Congress of International College of Angiology, Bali, Indonesia, 18 - 20 September 2011.


Researcher : Yu WC

List of Research Outputs

Cheung T.T., Chan S.C., Chok K.S.H., Chan A.C.Y., Yu W.C., Poon R.T.P., Lo C.M. and Fan S.T., Rapid measurement of indocyanine green retention by pulse spectrophotometry: a validation study in 70 patients with Child-Pugh A cirrhosis before hepatectomy for hepatocellular carcinoma, Hepatobiliary & Pancreatic Diseases International. 2012, 11(3): 267-271.
Fan S.T., Yang Z., Ho D.W.Y., Ng N.P., Yu W.C. and Wong J., Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study, Annals of Surgery. 2011, 254(4): 569-576.
Ho D.W.Y., Yang Z., Yi K., Lam C.T., Ng N.P., Yu W.C., Lau J.C.S., Wan T.M.H., Wang X., Yan Z., Liu H., Zhang Y. and Fan S.T., Gene expression profiling of liver cancer stem cells by RNA-sequencing, PLoS One. 2012, 7(5): e37159.
Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.


Researcher : Yuen PW

Project Title:Crile Centennial Symposium Pathology and Staging: Problems and Future Directions
Investigator(s):Yuen PW
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2006




Researcher : Yuen WK

List of Research Outputs

Leung G.K.K. and Yuen W.K., Operative intervention for traumatic brain injuries in the elderly, The 5th Asian Epilepsy Surgery Congress cum 18th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, 9 - 12 November 2011.
Leung G.K.K., Yuen W.K., Wong H.T. and Li L.F., Operative intervention for traumatic brain injury in the elderly, The 36th Annual Scientific Meeting of the Royal College of Surgeons of Thailand, Pattaya, Thailand, 14 - 17 July 2011.
Wong W.H., Wong H.T., Tong D.K.H., Leung G.K.K. and Yuen W.K., Utilization of whole body computed tomography (WB-CT) for trauma patients, The Advanced Trauma Life Support Region XVI Meeting, Malaysia. 2012.


Researcher : Yung SYJ

List of Research Outputs

Chow H.M., Yung S.Y.J. and Ngan E.S.W., Neural crest derived from Hirschsprung iPS cells show a reduced neural plasticity, Days of Molecular Medicine 2011, Hong Kong, 10-12 November 2011.
Yung S.Y.J., Tse H.F., Tam P.K.H. and Ngan E.S.W., Establishing a patient-specific iPSC model for Hirschsprung’s disease and other neural crest-associated diseases, The 10th Annual Meeting of the International Society for Stem Cell Research, Yokohama, Japan, 13 - 16 June 2012.
Yung S.Y.J., Chow H.M., Tse H.F., Tam P.K.H. and Ngan E.S.W., Generation of patient-specific iPSCs for Hirschsprung's disease modelling, Days of Molecular Medicine 2011, Hong Kong, 10-12 November 2011.
Yung S.Y.J., Tse H.F., Wan T.S.K., Tam P.K.H. and Ngan E.S.W., Modelling Hirschsprung’s disease using patient-specific iPS cells, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25 - 28 March 2012.
Yung S.Y.J., Tse H.F., Tam P.K.H. and Ngan E.S.W., iPS cell-derived neural crest cells from a patient with Hirschsprung's disease show a reduced differentiation plasticity, The 10th Annual Meeting of the International Society for Stem Cell Research, Yokohama, Japan, 13 - 16 June 2012.


Researcher : Zhang R

List of Research Outputs

Lee P.Y., Zhang R., Li V., Liu X., Sun R.W.Y., Che C.M. and Wong K.K.Y., Enhancement of anticancer efficacy using modified lipophilic nanoparticle drug encapsulation, International Journal of Nanomedicine. 2012, 7: 731-737.
So M.T., Leon Y.Y., Cheng G., Tang S.M., Miao X., Cornes B.K., Ngo D.N., Cui L., Ngan E.S.W., Lui V.C.H., Wu X.Z., Wang B., Wang H.L., Yuan Z.W., Huang L.M., Li L., Xia H.M., Zhu D., Li J.C., Nguyen T.L., Chan I.H.Y., Chung H.Y., Liu X., Zhang R., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., RET mutational spectrum in Hirschsprung disease: evaluation of 601 Chinese patients, PLoS One. 2011, 6(12): e28986.


Researcher : Zhang W

List of Research Outputs

Wang X., Lo C.M., Chen L., Cheung C.K.Y., Yang Z., Chen Y.X., Ng N.P., Yu W.C., Ming X., Zhang W., Ho D.W.Y., Chan S.C. and Fan S.T., Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver, Hepatology. 2012, Epub on 2012-04-27.
Wang X., Zhang W., Lui E.L.H., Zhu Y., Lu P., Yu X., Sun J., Yang S., Poon R.T.P. and Fan S.T., Notch1-Snail1-E-cadherin pathway in metastatic hepatocellular carcinoma, International Journal of Cancer. 2011, 131(3): E163-172.


Researcher : Zhang X

List of Research Outputs

Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in human malignant gliomas: a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide, The Society for NeuroOncology. 2011.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Acquired temozolomide resistance in malignant gliomas - a proteomics approach and the role of prolyl 4-hydroxylase, beta polypeptide (P4HB) (Abstract), Neuro-oncology. 2011, 13(3): 111.
Leung G.K.K., Sun S., Wong S.T.S., Zhang X., Pu J.K.S. and Lui W.M., Identifying molecular candidates associated with acquired temozolomide resistance in human malignant glioma - a proteomics approach., The 14th European Congress of Neurosurgery, Rome, Italy, 9 - 14 October 2011.
Sun S., Wong S.T.S., Zhang X., Pu J.K.S., Lee N.P.Y., Day P.J., Ng K.B., Lui W.M. and Leung G.K.K., Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines , Journal of Neuro-oncology. 2012, 107(1): 89-100.
Zhang X., Sun S., Pu J.K.S., Tsang C.O.A., Lee D., Lui W.M., Wong S.T.S., Leung G.K.K. and Man V.O.Y., Long non-coding RNA expression profiles predict clinical phenotypes in glioma, Neurobiology of Disease. 2012, 48(1): 1-8.


Researcher : Zhu J

List of Research Outputs

Cui L., Wong E.H.M., Zhu J., Almeida M.F. .D.E., Tam P.K.H. and Garcia-Barcelo M.M., Genetic study of a family segregating Shah-Waardenburg syndrome, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.
Zhu J., Garcia-Barcelo M.M., Tam P.K.H. and Lui V.C.H., RET transcriptional regulation by HOXB5 in Hirschsprung's disease, The 3rd International Symposium on Development of the Enteric Nervous System Cells, Signals and Genes, Hong Kong, 25-28 March 2012.


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