DEPT OF OBSTETRICS & GYNAECOLOGY



Researcher : Cai C

List of Research Outputs

Cai C., Chan D.W. and Ngan H.Y.S., TAK1 overexpression contributes to aggressive ovarian cancer, 18th Hong Kong International Cancer Congress 2011.


Researcher : Cao M

List of Research Outputs

Cao M., Chan R.W.S. and Yeung W.S.B., Identification of endometrial label retaining cells in postpartum mice, Days of Molecular Medicine 2012. 10-12 November 2011, Hong Kong . 2011.


Researcher : Cao S

List of Research Outputs

Cao S., Yeung W.S.B. and Lee C.K.F., Functional Study of an Acrosome-Expressing Gene, VAD1.2 in Mice Spermatogenesis. P.583, The 44th Annual Meeting. Society for the Study of Reproduction. July 31 – Aug 4, 2011, Portland, Oregon . 2011.


Researcher : Chai J

Project Title:A prospective randomized comparison trial on the use of mifepristone with sublingual or buccal misoprostol for medical abortions of less than 9 weeks gestation
Investigator(s):Chai J, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:08/2010


Project Title:A pilot study on the combined use of letrozole, mifepristone and misoprostol in termination of first trimester pregnancy up to 9 weeks gestation
Investigator(s):Chai J, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2011


Project Title:10th RCOG International Scientific Congress A randomized clinical trial comparing the sublingual and buccal routes of administration of misoprostol after mifepristone for medical abortions of up to 63 days gestation
Investigator(s):Chai J
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2012


List of Research Outputs

Chai J., Hon E., Li I.C.F., Pun T.C., Yeung W.S.B. and Ho P.C., A pilot study of pre-operative misoprostol in reducing operative blood loss during hysterectomy, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2011, 158(1): 72-5.
Chai J. and Ho P.C., A randomized clinical trial comparing the side effects of sublingual and buccal routes of misoprostol administration for medical abortions up to 63 days gestation, 10th RCOG International Scientific Congress. 2012.
Chai J., Hong Kong Academy of Medicine - Dedicated CME programme for non-fellows 2012 - Dysfunctional uterine bleeding, Hong Kong Academy of Medicine. 2012.
Chai J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Ovarian stimulation modulates steroid receptor expression and spheroid attachment in peri-implantation endometria: studies on natural and stimulated cycles, Fertility Sterility. 2011, 96(3): 764-768.
Tsang H., Cheung T.Y., Kodithuwakku K.S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. , Reprod Toxicol . 2012, 33: 60-66.


Researcher : Chan CCW

List of Research Outputs

Lee V.C., Chan C.C.W., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Sequential use of letrozole and gonadotrophin in women with poor ovarian reserve: a randomized controlled trial, Reproductive BioMedicine Online 2011. 2011, 23(3): 380-8.


Researcher : Chan DW

Project Title:Identification of putative miRNAs involved in chemoresistance of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2010
Completion Date:09/2011


Project Title:The functional impact of AMP-activated protein kinase gamma-2 (AMPK-g2)subunit expression on AMPK activity and oncogenesis in ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2011


Project Title:Functional Characterization of Has-miR-141, a Putative Oncogene in Promoting Anchorage-Independent Growth Ability of Ovarian Cancer Cells
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012


Project Title:AACR Annual Meeting 2012 Targeting GRB7/ERK/FOXM1 signaling cascade is a promising therapeutic approach in ovarian cancer
Investigator(s):Chan DW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2012
Completion Date:04/2012


List of Research Outputs

Cai C., Chan D.W. and Ngan H.Y.S., TAK1 overexpression contributes to aggressive ovarian cancer, 18th Hong Kong International Cancer Congress 2011.
Chan D.W. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 signaling cascade is a promising therapeutic approach in ovarian cancer, AACR Annual Meeting 2012, Chicago, IL, USA. 2012.
Chan D.W., The functional role of AMP-activated protein kinase gamma-2 (AMPK-g2) subunit in AMPK activity and ovarian cancer , Croucher Advanced Study Institute (ASI) 2012.
Chan D.W. and Ngan H.Y.S., The potential molecular therapeutic approach in targeting ovarian clear cell carcinoma, Gynecology & Obstetrics. OMICS Group, 2012, 2: 1000e103.
Chan D.W., Liu V.W.S., Leung L.Y., Yao K.M., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells, J Pathol. 2011, 225(4): 525-34.
Fung K.C.F., Chan D.W., Liu V.W.S., Leung T.H.Y., Cheung A.N.Y. and Ngan H.Y.S., Increased expression of PITX2 transcription factor contributes to ovarian cancer progression, PLos One. PLos, 2012, 7: e37076.
Hui W.Y., Chan D.W. and Ngan H.Y.S., DLX1, a putative downstream target of FOXM1, in regulating ovarian tumorigenesis, The EMBO Meeting 2011 - advancing the life sciences - Vienna. Vienna, Austria, 2011.
Hui W.Y., Chan D.W. and Ngan H.Y.S., Identification of DLX1 as a FOXM1 downstream target in mediating ovarian cancer oncogenesis, 18th Hong Kong International Cancer Congress 2011.
Leung T.H.Y., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., Indetification and characterization of cancer stem-like cells in cervical cancer, , Asia-Oceania Research Organization in Genital Infection and Neoplasia (AOGIN) 2012, Hong Kong. 2012.
Leung T.H.Y., Wong S.C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., Significance of p73 in the sensitivity of cancer treatment in gynaecological cancers, Tumor Microenvironment-New Concepts and Molecular Mechanisms, Croucher Advanced Study Institute 2012, Hong Kong. 2012.
Li C., Liu V.W.S., Chan D.W., Yao K.M. and Ngan H.Y.S., LY294002 and Metformin Cooperatively Enhance the Inhibition of Growth and the Induction of Apoptosis of Ovarian Cancer Cells., Int J Gynecol Cancer.. 2011, 22: 15-22.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of miR-199b-5p is associated with chemoresistance via Jagged 1 in human ovarian cancer, 18th Hong Kong International Cancer Congress 2011.
Liu X., Chan D.W. and Ngan H.Y.S., Mechanisms of Chemoresistance in Human Ovarian Cancer at a Glance, Gynecology & Obstetrics. 2012, 2: 1000e104.
Lok T.M., Chan D.W., Liu V.W.S., Hui W.Y., Leung T.H.Y., Yao K.M. and Ngan H.Y.S., Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells, PLoS One. 2011, 6: e23790.
Mak S.L., Chan D.W. and Ngan H.Y.S., Functional characterization of Has-miR-141, a putative oncogene in promoting anchorage-independent growth ability of ovarian cancer cells, 18th Hong Kong International Cancer Congress 2011.
Mak S.L., Chan D.W. and Ngan H.Y.S., miR-141 confers anoikis resistance of ovarian cancer cells by targeting KLF12, AACR Annual Meeting 2012, Chicago, IL, USA. 2012.


Researcher : Chan KKL

Project Title:Relationship between placental ratio and placental function
Investigator(s):Chan KKL, Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding for New Staff
Start Date:01/2003


Project Title:The effect of fulvestrant in epithelial ovarian cancer with differential estrogen receptor status in mice
Investigator(s):Chan KKL, Liu S, Tam KF, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2008


Project Title:Selective hormonal treatment in ovarian cancer
Investigator(s):Chan KKL, Leung THY, Ngan HYS, Liu S
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2010
Completion Date:12/2011


Project Title:Sixth International Symposium on Hormonal Oncogenesis USE OF HIGHLY SELECTIVE ESTROGEN RECEPTOR MODULATORS IN OVARIAN CANCER
Investigator(s):Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2010


Project Title:Evaluation of human epididymal secretory protein ( HE4 ) for monitoring for ovarian cancer recurrence
Investigator(s):Chan KKL, Liu S, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2011


List of Research Outputs

Chan D.W., Liu V.W.S., Leung L.Y., Yao K.M., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells, J Pathol. 2011, 225(4): 525-34.
Chan K.K.L., Estrogen receptors in ovarian cancer, Asia-Oceanic Federation in Obstetrics and Gynaecology ( AOFOG ). 2011.
Chan K.K.L., Kwan T.T.C., Yao T., Tam K.F., Cheung A.N.Y. and Ngan H.Y.S., Human papillomavirus vaccine: What are women most concerned about?, J Obstet Gynaecol Res. 2012, 38(1): 23-30.
Chan K.K.L., Lymph node dissection issues in low risk endometrial cancer, Asia Clinical Oncology Society . 2012.
Chan K.K.L., Pelvic mass risk assessment for ovarian cancer, Asia Oncology Summit. 2012.
Chan K.K.L., The Role of HE4 in Risk of Ovarian Cancer Assessment, Asia-Oceanic Federation of Obstetrics and Gynaecology ( AOFOG ). 2011.
Cheung A.N.Y. and Chan K.K.L., Perplexing hCG profile after evacuation of hydatidiform mole, Lancet. 2012, 379: 98-100.
Kondalsamy-Chennakesavan S., Janda M., Gebski V., Baker J., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K.F., Chan K.K.L., Wrede D.H., Pather S., Simcock B., Farrell R., Robertson G., Walker G., McCartney A. and Obermair A., Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial, Eur J Cancer, Apri 12 . 2012.
Kwan T.T.C., Lo S.S., Tam K.F., Chan K.K.L. and Ngan H.Y.S., Assessment of knowledge and stigmatizing attitudes related to human papillomavirus among Hong Kong Chinese healthcare providers, Int J Gynaecol Obstet. 2012, 116(1): 52-6.
Leung T.H.Y., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., Indetification and characterization of cancer stem-like cells in cervical cancer, , Asia-Oceania Research Organization in Genital Infection and Neoplasia (AOGIN) 2012, Hong Kong. 2012.
Leung T.H.Y., Wong S.C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., Significance of p73 in the sensitivity of cancer treatment in gynaecological cancers, Tumor Microenvironment-New Concepts and Molecular Mechanisms, Croucher Advanced Study Institute 2012, Hong Kong. 2012.
Obermair A., Janda M., Baker J., Kondalsamy-Chennakesavan S., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K.F., Chan K.K.L., Wrede D.H., Pather S., Simcock B., Farrell R., Robertson G., Walker G., McCartney A. and Gebski V., Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: results from a randomised controlled trial, Eur J Cancer, 2012 May. 2012, 48(8): 1147-53.
Wei N., Liu S., Chan K.K.L. and Ngan H.Y.S., Tumour Suppressive Function and Modulation of Programmed Cell Death 4 (PDCD4) in Ovarian Cancer, PLoS One. 2012.


Researcher : Chan RWS

Project Title:11th World Congress on Endometriosis Macrophages Increased the Colony Forming Activity of Putative Endometrial and Endometriotic Stromal Stem Cells
Investigator(s):Chan RWS
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2011
Completion Date:09/2011


List of Research Outputs

Cao M., Chan R.W.S. and Yeung W.S.B., Identification of endometrial label retaining cells in postpartum mice, Days of Molecular Medicine 2012. 10-12 November 2011, Hong Kong . 2011.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophage promoted the colony forming ability of putative endometrial stromal stem cells, Days of Molecular Medicine 2012, 10-12 November 2011, Hong Kong. 2011.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophages Increased the Colony Forming Activity of Putative Endometrial and Endometriotic Stromal Stem Cells, World Congress for Endometriosis. 2011.
Chan R.W.S., Kaitu'u-Lino T. and Gargett C.E., Role of Label-Retaining Cells in Estrogen-Induced Endometrial Regeneration, Reproductive Sciences. 2012, 19: 102-114.
Xiang L., Chan R.W.S. and Yeung W.S.B., Development of a fluorescent cell tracking technique for isolation of human endometrial stromal stem/progenitor cells, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 6 November 2011, Hong Kong.. 2011.
Xiang L., Chan R.W.S. and Yeung W.S.B., Identification of putative human endometrial stem cells using fluorescent cell tracking. O.2.23., The 16th Research Postgraduate Symposium, HKU. December 7-8, 2011, Hong Kong. 2011.


Researcher : Chan SY

List of Research Outputs

Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.


Researcher : Chan YK

Project Title:Validating and examining SNPs identified from genome-wide scanning for disease susceptibility to HBV-related liver cancer in Chinese population
Investigator(s):Chan YK, Ng IOL, Wong CM
Department:Pathology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2010


List of Research Outputs

Long J., Cai Q., Sung H., Shi J., Zhang B., Choi J.Y., Wen W., Delahanty R.J., Lu W., Gao Y.T., Shen H., Park S.K., Chen K., Shen C.Y., Ren Z., Haiman C.A., Matsuo K., Kim M.K., Khoo U.S., Iwasaki M., Zheng Y., Xiang Y.B., Gu K., Rothman N., Wang W., Hu Z., Liu Y., Yoo K.Y., Noh D.Y., Han B.G., Lee M.H., Zheng H., Zhang L., Wu P.E., Shieh Y.L., Chan S.Y., Wang S., Xie X., Kim S.W., Henderson B.E., Le Marchand L., Ito H., Kasuga Y., Ahn S.H., Kang H.S., Chan Y.K., Iwata H., Tsugane S., Li C., Shu X.O., Kang D.H. and Zheng W., Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer, PLoS Genet. 2012, 8(2): e1002532.


Researcher : Chan YY

List of Research Outputs

Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophage promoted the colony forming ability of putative endometrial stromal stem cells, Days of Molecular Medicine 2012, 10-12 November 2011, Hong Kong. 2011.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophages Increased the Colony Forming Activity of Putative Endometrial and Endometriotic Stromal Stem Cells, World Congress for Endometriosis. 2011.


Researcher : Chan YY

List of Research Outputs

Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophage promoted the colony forming ability of putative endometrial stromal stem cells, Days of Molecular Medicine 2012, 10-12 November 2011, Hong Kong. 2011.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophages Increased the Colony Forming Activity of Putative Endometrial and Endometriotic Stromal Stem Cells, World Congress for Endometriosis. 2011.


Researcher : Cheong AWY

List of Research Outputs

Cheong A.W.Y., Liu W.M., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., MiR-let-7a regulates integrin-b3 expression and modulates mouse blastocyst attachment in vitro. P.02. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Cheong A.W.Y., Liu W.M., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Role of MicroRNA Let-7 in the implantation of mouse blastocyst. P.1.02, The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.
Liu W., Pang R.T.K., Cheong A.W.Y., Lee C.K.F. and Yeung W.S.B., Excellent Poster Presentation: Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, 2nd SKLRB Symposia on “Frontiers in Reproductive Biology. 2012.
Liu W., Pang R.T.K., Cheong A.W.Y., Ng E.H.Y., Lao K., Lee C.K.F. and Yeung W.S.B., Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, PLoS One. 2012, 7(5): 1-12.


Researcher : Cheung ANY

Project Title:Selecting most suitable students for production of best medical doctors-which criteria should we use?
Investigator(s):Cheung ANY, Patil NG, Ip MSM, Chan LC
Department:Pathology
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:02/2005


Project Title:Folate and folate receptor alpha in ovarian cancers
Investigator(s):Cheung ANY, Siu KY
Department:Pathology
Source(s) of Funding:Small Project Funding
Start Date:01/2007


Project Title:Akt and p21-activated kinase signaling pathways in gestational trophoblastic disease
Investigator(s):Cheung ANY, Ngan HYS, Siu KY
Department:Pathology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2007


Project Title:Cervical cancer screening by enhanced cervical cytology-application of novel markers
Investigator(s):Cheung ANY, Ngan HYS, Guan X
Department:Pathology
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:03/2007


Project Title:Centre for Research into Circulating Fetal Nucleic Acids
Investigator(s):Cheung ANY
Department:Pathology
Source(s) of Funding:Areas of Excellence Scheme
Start Date:01/2008


Project Title:Tropomyosin-related kinase B and Brain-derived neurotrophic factor in ovarian cancer
Investigator(s):Cheung ANY, Siu KY, Ngan HYS
Department:Pathology
Source(s) of Funding:Small Project Funding
Start Date:01/2008


Project Title:FBI-1 in ovarian carcinogenesis and progression
Investigator(s):Cheung ANY, Siu KY, Ngan HYS
Department:Pathology
Source(s) of Funding:Small Project Funding
Start Date:01/2009


Project Title:HPV detection as an adjunct for triage of atypical cervical cytology in screening for cervical cancer
Investigator(s):Cheung ANY
Department:Pathology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:11/2009


Project Title:Hedgehog pathway regulator Kif7 in gestational trophoblastic disease
Investigator(s):Cheung ANY, Ngan HYS, Siu KY, Wong GW
Department:Pathology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010
Completion Date:02/2012


Project Title:DOCK180 in ovarian cancer progression
Investigator(s):Cheung ANY, Siu KY
Department:Pathology
Source(s) of Funding:Small Project Funding
Start Date:01/2011
Completion Date:12/2012


Project Title:XVITH WORLD CONGRESS ON GESTATIONAL TROPHOBLASTIC DISEASES p21-activated kinase signaling in Gestational Trophoblastic Diseases
Investigator(s):Cheung ANY
Department:Pathology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2011
Completion Date:10/2011


Project Title:p21-activated kinase 4 in chemosensitivity of ovarian cancer
Investigator(s):Cheung ANY, Ngan HYS, Wong GW
Department:Pathology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2012


Project Title:FBI-1 (Pokemon) in Gestational Trophoblastic Disease
Investigator(s):Cheung ANY, Ngan HYS, Siu KY, Wong GW
Department:Pathology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Tumour Microenvironment - New concepts and molecular mechanisms
Investigator(s):Cheung ANY, Ng IOL, Khoo US, Lung ML, Ngan HYS
Department:Pathology
Source(s) of Funding:Croucher Advanced Study Institute
Start Date:01/2012


Project Title:HPV detection as an adjunct for triage of atypical cervical cytology in screening for cervical cancer
Investigator(s):Cheung ANY, Ngan HYS
Department:Pathology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:02/2012


List of Research Outputs

Chan K.K.L., Kwan T.T.C., Yao T., Tam K.F., Cheung A.N.Y. and Ngan H.Y.S., Human papillomavirus vaccine: What are women most concerned about?, J Obstet Gynaecol Res. 2012, 38(1): 23-30.
Cheung A.N.Y. and Chan K.K.L., Perplexing hCG profile after evacuation of hydatidiform mole, Lancet. 2012, 379: 98-100.


Researcher : Cheung TY

List of Research Outputs

Cheung T.Y., Tsang H., Wong C.K., Yeung W.S.B. and Lee C.K.F., The endocrine disruptive chemical bispenol modulates Wnt-signaling for spheroid attachment onto endometrial cells. P.03. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction, Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Tsang H., Cheung T.Y., Kodithuwakku K.S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. , Reprod Toxicol . 2012, 33: 60-66.


Researcher : Cheung TY

List of Research Outputs

Cheung T.Y., Tsang H., Wong C.K., Yeung W.S.B. and Lee C.K.F., The endocrine disruptive chemical bispenol modulates Wnt-signaling for spheroid attachment onto endometrial cells. P.03. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction, Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Tsang H., Cheung T.Y., Kodithuwakku K.S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. , Reprod Toxicol . 2012, 33: 60-66.


Researcher : Cheung VYT

List of Research Outputs

Cheung V.Y.T., Yang F. and Leung K.Y., 2D versus 3D transabdominal sonography for the measurement of lower uterine segment thickness in women with previous cesarean delivery. , Int J Gynaecol Obstet. 2011 Sep;114(3):234-7. Epub 2011 Jul 2. . 2011, 114: 234-7.
Cheung V.Y.T., Further evidence against the reliability of the human chorionic gonadotropin discriminatory level. , J Ultrasound Med. 2012 May;31(5):817;. 2012, 31: 817.
Cheung V.Y.T., High internsity focused ultrasound in the treatment of uterine fibroids, Postgraduate Study Day, Department of Obstetrics and Gynaecology, Queen Mary Hospital. 2012.
Cheung V.Y.T., Management of ectopic pregnancy, Postgraduate Study Day, Department of Obstetrics and Gynaecology, Queen Mary Hospital . 2011.
Cheung V.Y.T., Non-tubal ectopic pregnancies: diagnosis and management, Certificate Course on Ultrasonography on Pregnancy and Women Health Issues . 2012.
Ko K.Y.J., Wan H.L., Ngu S.F., Cheung V.Y.T. and Ng E.H.Y., Cesarean scar molar pregnancy, Obstet Gynecol. 2012, 119(2 Pt 2): 449-51.
Ngu S.F., Cheung V.Y.T. and Pun T.C., A Prospective Randomized Study on Vaginoscopic Hysteroscopy versus Traditional Hysteroscopy, Postgraduate Study Day, Department of Obstetrics and Gynaecology, Queen Mary Hospital. 2011.
Ngu S.F., Cheung V.Y.T. and Pun T.C., A Prospective Randomized Study on Vaginoscopy and H Pipelle versus Traditional Hysteroscopy and Standard Pipelle, 10th RCOG International Scientific Congress, Kuching, Malaysia. 2012.
Ngu S.F. and Cheung V.Y.T., An update on the management of acute pelvic inflammatory disease, The Hong Kong Medical Diary. 2011, 16: 9-11.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Left upper quadrant approach in gynecologic laparoscopic surgery, In: 2011 Dec;90(12):1406-9., Acta Obstet Gynecol Scand. 2011, 90(12): 1406-9.
Ngu S.F. and Cheung V.Y.T., Non-tubal ectopic pregnancy, Int J Gynaecol Obstet. 2011, 115(3): 295-7.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Randomized Study of Vaginoscopy and H Pipelle vs Traditional Hysteroscopy and Standard Pipelle, J Minim Invasive Gynecol. 2012, 19(2): 206-11.
Ngu S.F. and Cheung V.Y.T., Vulvar endometriosis, J Obstet Gynaecol Can. 2011, 33: 891.


Researcher : Chiu CN

Project Title:The role of sperm fucosyltransferase-5 on sperm-oviductal epithelial cell interaction
Investigator(s):Chiu CN, Lee CL, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010


Project Title:Control of human trophoblast invasion by CD147
Investigator(s):Chiu CN, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2011


Project Title:The roles of protein disulfide isomerase family A, member 3 (ERp57) and surface thiol/disulfide exchange in spermatozoa-zona pellucida binding and their association with fertilization in vitro.
Investigator(s):Chiu CN, Pang RTK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Defective sialyl-Lewis(x) expression on human zona pellucida as a potential cause of subfertilty
Investigator(s):Chiu CN, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2012


List of Research Outputs

Chiu C.N., Lam K.K., Lee C.L., Huang V.W., Wong B.S., Zhao W., Li K., Ho P.C. and Yeung W.S.B., Adrenomedullin enhances the progressive motility and zona pellucida-binding capacity of spermatozoa from normozoospermic but not asthenozoospermic men, Molecular Reproduction and Development. 2012, 79(2): 76.
Huang W., Chiu C.N., Yeung W.S.B. and Ho P.C., Sperm fucosyltransferase-5 interacts with oviductal cell membrane proteins to protect human spermatozoa from oxidative stress., In: Society for the Study of Reproduction, 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A., JUL 31-AUG 4.. U.S.A., 2011.
Lam K.K., Lee C.L., Lee C.K.F., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A interacts with siglec-6 to suppress trophoblast invasion. P.08., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Lam P.Y., Lau E., Siu S.O., Ng C.M.D., Kong P.W., Chiu C.N., Yeung W.S.B., Lo C.S.C. and Chu I.K., Online combination of reversed-phase/reversed-phase and porous graphitic carbon liquid chromatography for multicomponent separation of proteomics and glycoproteomics samples., Electrophoresis. 2011, 32: 2930-40.
Lam Y.F.E., Lee C.L., Yeung W.S.B. and Chiu C.N., The immunomodulatory properties of glycodelin-A on human monocyte and macrophage., In: Society for the Study of Reproduction., 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A, JUL 31-AUG 4.. U.S.A, 2011.
Lee C.L., Chiu C.N., Pang P.C., Chu I.K., Lee C.K.F., Koistinen R., Koistinen H., Seppala M., Morris H.R., Tissot B., Panico M., Dell A. and Yeung W.S.B., HKU Strategic Research Areas & Themes “Reproduction and Development” Best Research Output Award 2011 (2nd Prize): Glycosylation failure extends to glycoproteins in gestational diabetes: Evidence from reduced alpha 2-6 sialylation and impaired immunomodulatory activities of pregnancy-related glycodelin-A. Diabetes. 2011;60(3):909-17., HKU Strategic Research Areas & Themes “Reproduction and Development”. 2011.
Liu W., Pang R.T.K., Chiu C.N., Wong B.P.C., Lao K., Lee C.K.F. and Yeung W.S.B., Sperm-borne microRNA-34c is required for the first cleavage division in mouse, PNAS. 2012, 109: 490-4.
Pang P.C., Chiu C.N., Lee C.L., Chang L.Y., Panico M., Morris H.R., Haslam S.M., Khoo K.H., Clark G.F., Yeung W.S.B. and Dell A., Faculty of 1000 “Naturally Selected” on December 2011: Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida. Science. 2011;333(6050):1761-4. , Faculty of 1000. 2011.
Pang P.C., Chiu C.N., Lee C.L., Chang L.Y., Panico M., Morris H.R., Haslam S.M., Khoo K.H., Clark G.F., Yeung W.S.B. and Dell A., Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida., Science. 2011, 333: 1761-4.
Pang R.T.K., Lam K.W., Lee C.L., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclase activation elevates MiR-34A and suppresses invasion in the trophoblast cell line BeWo., World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Pang R.T.K., Lam K.W., Lee C.K.F., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclise activation elevates miR-34a and suppresses invasion in the trophoblast cell line BeWo, The 2nd world congress on reproductive biology, 9-12 October 2011, Cairns, Australia. 2011.
Wong S.T., Yeung W.S.B. and Chiu C.N., Adrenomedullin stimulates human trophoblast invasion through the upregulation of nitric oxide and urokinase plasminogen activator activity., In: Society for the Study of Reproduction, 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A., JUL 31-AUG 4.. U.S.A., 2011.
Yeung W.S.B. and Chiu C.N., Glycodelin-C and the role of cumulus complex in natural sperm quality selection. , World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Yeung W.S.B. and Chiu C.N., SLeX: potential implications for fertility and contraception, Expert Review of Obstetrics & Gynecology. 2012, 7: 1-3.


Researcher : Choi WK

List of Research Outputs

Zhong L., Tong Y., Tang G.W.K., Choi W.K. and Sze C.W., A Randomized Placebo-controlled trial on the effectiveness of a Chinese herbal formula to alleviate menopausal symptoms, The 10th Meeting of Consortium for Globalization of Chinese Medicine. 2011, 168.


Researcher : Fung KCF

List of Research Outputs

Fung K.C.F., Chan D.W., Liu V.W.S., Leung T.H.Y., Cheung A.N.Y. and Ngan H.Y.S., Increased expression of PITX2 transcription factor contributes to ovarian cancer progression, PLos One. PLos, 2012, 7: e37076.


Researcher : Gao J

List of Research Outputs

Gao J., Zuo Y., So K.H., Yeung W.S.B., Ng E.H.Y. and Lee C.K.F., Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. , Spermatogenesis . 2012, 2(1): 53-62.
Gao J., Zuo Y., Yeung W.S.B. and Lee C.K.F., Potential role of VAD1.3 in spermatogenesis and fertilization. O.2.05. , The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.


Researcher : Gao J

List of Research Outputs

Gao J., Zuo Y., So K.H., Yeung W.S.B., Ng E.H.Y. and Lee C.K.F., Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. , Spermatogenesis . 2012, 2(1): 53-62.
Gao J., Zuo Y., Yeung W.S.B. and Lee C.K.F., Potential role of VAD1.3 in spermatogenesis and fertilization. O.2.05. , The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.


Researcher : Ho PC

Project Title:A double-blind randomized placebo controlled trial on the use of misoprostol with or without letrozole for termination of second trimester pregnancy
Investigator(s):Ho PC, Ng EHY, Yeung WSB, Lee VCY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:08/2010
Completion Date:07/2011


Project Title:Studies on the effects of ulipristal on sperm functions
Investigator(s):Ho PC, Ng EHY, Li RHW, Yeung WSB, Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2012


List of Research Outputs

Chai J., Hon E., Li I.C.F., Pun T.C., Yeung W.S.B. and Ho P.C., A pilot study of pre-operative misoprostol in reducing operative blood loss during hysterectomy, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2011, 158(1): 72-5.
Chai J. and Ho P.C., A randomized clinical trial comparing the side effects of sublingual and buccal routes of misoprostol administration for medical abortions up to 63 days gestation, 10th RCOG International Scientific Congress. 2012.
Chai J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Ovarian stimulation modulates steroid receptor expression and spheroid attachment in peri-implantation endometria: studies on natural and stimulated cycles, Fertility Sterility. 2011, 96(3): 764-768.
Chan C.H.Y., Chan C.L.W., Ng E.H.Y., Ho P.C., Chan T.H.Y., Lee G.L. and Hui W.H.C., Incorporating spirituality in psychosocial group intervention for women undergoing in vitro fertilization: A prospective randomized controlled study, Psychology and Psychotherapy: Theory, Research and Practice. 2011, 2011: 1-18.
Chan E.K.L., Brownridge D.A., Tiwari A.F.Y., Fong D.Y.T., Leung W.C. and Ho P.C., Associating pregnancy with partner violence against Chinese women, Journal of Interpersonal Violence. 2011, 26(7): 1478-1500.
Chan E.K.L., Brownridge D.A., Fong D.Y.T., Tiwari A.F.Y., Leung W.C. and Ho P.C., Violence against pregnant women can increase the risk of child abuse: A longitudinal study, Child Abuse & Neglect. 2012, 36(4): 275-284.
Chiu C.N., Lam K.K., Lee C.L., Huang V.W., Wong B.S., Zhao W., Li K., Ho P.C. and Yeung W.S.B., Adrenomedullin enhances the progressive motility and zona pellucida-binding capacity of spermatozoa from normozoospermic but not asthenozoospermic men, Molecular Reproduction and Development. 2012, 79(2): 76.
Ho P.C., Clinical Applications of Letrozole in Reproductive Medicine., The Chinese Society of Reproductive Medicine. 2011, 1: 25.
Ho P.C., Director of Editorial Board in Obstetrics and Gynaecology, Journal of Paediatrics, Obstetrics and Gynaecology, 1997 till now. 2012.
Ho P.C., Making first trimester abortions safer, Presented in the 4th Asia Pacific Congress in Gynecology, Infertility and Perinatology in collaboration with The Royal Thai College of Obstetricians and Gynecologists, Bangkok, Thailand, November 24-27, 2011. 2011.
Ho P.C., Member of Editorial Board, Chinese Journal of Obstetrics and Gynaecology. 2012.
Ho P.C., Member of Editorial Board, Clinical Obstetrics and Gynaecology (Bailliere Tindall). 2012.
Ho P.C., Member of Editorial Board, Journal of Practical Obstetrics and Gynaecology. 2012.
Ho P.C., Member of Editorial Board, Journal of Reproductive Medicine (China). 2012.
Ho P.C., Member of the Advisory Editorial Board, Asia Oceania Journal of Obstetrics and Gynaecology, 1994 till now. 2012.
Ho P.C., New challenges of hormonal contraception, Presented in the 4th Asia Pacific Congress in Gynecology, Infertility and Perinatology in collaboration with The Royal Thai College of Obstetricians and Gynecologists, Bangkok, Thailand, November 24-27, 2011. 2011.
Ho P.C., Ovarian reserve markers for individualization of ovarian stimulation protocol (个体化卵巢刺激方案中卵巢储备功能的标记物), 不孕不育治疗方案的个体化,从理论到实践,资料汇编,主办单位:广东省医学会, 中山大学孙逸仙纪念医院,广州‧2012年5月11日–13日, Guang Dong Medical Association. 2012.
Ho P.C., Ovarian stimulation and endometrial receptivity, Presented in Concurrent Symposium in the 16th World Congress on In Vitro Fertilization, Tokyo, Japan, September 10-13, 2011. 2011.
Ho P.C., Reproduction in the brave new world, Presented in the XXII Asian and Oceanic Congress of Obstetrics and Gynecology "New Frontiers in Women's Health", in Taipei, Taiwan, September 23-27, 2011. 2011.
Ho P.C., Reproduction in the brave new world, Saudi Obstetrics and Gynecological Society: 21st Annual Scientific Meeting, in Collaboration with Asian Oceania Federation of Obstetrics and Gynecology (Challenges in Women's Health), March 19-22, 2012. 2012.
Ho P.C., Reviewer for "American Journal of Obstetrics and Gynaecology". 2012.
Ho P.C., Reviewer for "Obstetrics and Gynaecology". 2012.
Kodithuwakkul S.P., Pang R.T.K., Ng E.H.Y., Cheung A.N.Y., Horne A.W., Ho P.C., Yeung W.S.B. and Lee C.K.F., Wnt activation downregulates Olfactomedin-1 (Olfm-1) in Fallopian tubal epithelial cells: an microenvironment predisposed to tubal ectopic pregnancy, Laboratory Investigation . 2012, 92: 256-264.
Lam K.K., Lee C.L., Lee C.K.F., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A interacts with siglec-6 to suppress trophoblast invasion. P.08., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Lee V.C., Chan C.C.W., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Sequential use of letrozole and gonadotrophin in women with poor ovarian reserve: a randomized controlled trial, Reproductive BioMedicine Online 2011. 2011, 23(3): 380-8.
Lee V.C.Y., Tang F.O.S., Ng E.H.Y., Yeung W.S.B. and Ho P.C., A prospective double-blinded, randomized, placebo-controlled trial on the use of letrozole pretreatment with misoprostol for second-trimester medical abortion, Contraception 2011. 2011, 84(6): 628-33.
Lee V.C.Y., Yung S.F., Li R.H.W., Watzer B., Schweer H., Ng E.H.Y. and Ho P.C., A randomized comparison of pharmacokinetics of a single vaginal dose of dry misoprostol or misoprostol moistened with normal saline or with acetic acid, Human Reproduction. 2011, 26(11): 2981-7.
Li H.W., Anderson R.A., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Evaluation of serum antimullerian hormone and inhibin B concentrations in the differential diagnosis of secondary oligoamenorrhea, Fertility and Sterility 2011. 2011, 96(3): 774-9.
Li H.W.R., Gebbie A.E., Wong R.W.S., Ng E.H.Y., Glasier A.F. and Ho P.C., The use of sex hormones in women with rheumatological diseases, Hong Kong Medical Journal. 2011, 17: 1-5.
Li R.H.W., Ng E.H.Y. and Ho P.C., Polycystic Ovary Syndrome and Infertility, In: Editors: Jaideep Malhotra, Rohana Haththotuwa, Jaydeep D Tank, Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings) - Asia and Oceania Federation of Obstetrics and Gynaecology. 2011, Chapter 11: 105-111.
Li R.H.W., Wong C.Y.G., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Response to letter to the editor: Serum anti-Mullerian hormone level is not altered in women using hormonal contraceptives, Contraception. 2011, 85(5): 520-521.
Xin M., Lee C.Y.L., Yeung W.S.B. and Ho P.C., The Expression and Role of Adamts9 during Human Embryonic Stem Cell Differentiation, 1st annual Cambridge Stem Cell international symposium . 2011.


Researcher : Huang W

List of Research Outputs

Huang W., Chiu C.N., Yeung W.S.B. and Ho P.C., Sperm fucosyltransferase-5 interacts with oviductal cell membrane proteins to protect human spermatozoa from oxidative stress., In: Society for the Study of Reproduction, 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A., JUL 31-AUG 4.. U.S.A., 2011.


Researcher : Hui PW

Project Title:31st British International Congress of Obstetrics & Gynaecology 2007 A rare cause of Thrombocytopenia in Pregnancy-EDTA-dependent Pseudothrombocytopenia
Investigator(s):Hui PW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2007


List of Research Outputs

Hui P.W., Antenatal screening of Down’s syndrome in pregnancies conceived by ART, XXII Asian & Oceanic Congress of Obstetrics & Gynaecology, 23-27 September 2011, Taiwan. 2011.
Hui P.W., Case presentation, The 2nd fetoscopy workshop, 15-16 December 2011, Singapore. 2011.
Hui P.W., Microcystic lung lesion with fetal hydrops, Fetoscopy meeting, 8-10 September 2011, Hong Kong. 2011.
Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.
Liu A.P.Y., Ng Y.K., Hui P.W., Lau E.T.K., Tang M.H.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2011, 16: 188.


Researcher : Hui WY

List of Research Outputs

Hui W.Y., Chan D.W. and Ngan H.Y.S., DLX1, a putative downstream target of FOXM1, in regulating ovarian tumorigenesis, The EMBO Meeting 2011 - advancing the life sciences - Vienna. Vienna, Austria, 2011.
Hui W.Y., Chan D.W. and Ngan H.Y.S., Identification of DLX1 as a FOXM1 downstream target in mediating ovarian cancer oncogenesis, 18th Hong Kong International Cancer Congress 2011.
Lok T.M., Chan D.W., Liu V.W.S., Hui W.Y., Leung T.H.Y., Yao K.M. and Ngan H.Y.S., Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells, PLoS One. 2011, 6: e23790.


Researcher : Kan ASY

List of Research Outputs

Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.


Researcher : Ko KYJ

List of Research Outputs

Ko K.Y.J., Wan H.L., Ngu S.F., Cheung V.Y.T. and Ng E.H.Y., Cesarean scar molar pregnancy, Obstet Gynecol. 2012, 119(2 Pt 2): 449-51.


Researcher : Kodithuwakku KSPK

List of Research Outputs

Tsang H., Cheung T.Y., Kodithuwakku K.S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. , Reprod Toxicol . 2012, 33: 60-66.


Researcher : Kwan CK

List of Research Outputs

Ye T., Pang R.T.K., Leung O.N., Kwan C.K. and Yeung W.S.B., Comparison of early embryo attachment under atmospheric condition and oxygen tension on a three-dimensional endometrium-blastocyst implantation model, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.


Researcher : Kwan TTC

List of Research Outputs

Chan K.K.L., Kwan T.T.C., Yao T., Tam K.F., Cheung A.N.Y. and Ngan H.Y.S., Human papillomavirus vaccine: What are women most concerned about?, J Obstet Gynaecol Res. 2012, 38(1): 23-30.
Kwan T.T.C., Lo S.S., Tam K.F., Chan K.K.L. and Ngan H.Y.S., Assessment of knowledge and stigmatizing attitudes related to human papillomavirus among Hong Kong Chinese healthcare providers, Int J Gynaecol Obstet. 2012, 116(1): 52-6.


Researcher : Lai WSC

List of Research Outputs

Lai W.S.C., Lau E.W.L., Lo I.F.M., Chiu W.K., Law C.W., Tong T.M.F. and Lam S.T.S., Two cases of spondylothoracic dysostosis (Jarcho Levin syndrome) in Chinese population , The 9th Asia Pacific Conference on Human Genetics. 30th November - 3rd December 2010. . 2011.


Researcher : Lam KW

List of Research Outputs

Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Pang R.T.K., Lam K.W., Lee C.L., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclase activation elevates MiR-34A and suppresses invasion in the trophoblast cell line BeWo., World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Pang R.T.K., Lam K.W., Lee C.K.F., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclise activation elevates miR-34a and suppresses invasion in the trophoblast cell line BeWo, The 2nd world congress on reproductive biology, 9-12 October 2011, Cairns, Australia. 2011.


Researcher : Lam KW

List of Research Outputs

Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Pang R.T.K., Lam K.W., Lee C.L., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclase activation elevates MiR-34A and suppresses invasion in the trophoblast cell line BeWo., World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Pang R.T.K., Lam K.W., Lee C.K.F., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclise activation elevates miR-34a and suppresses invasion in the trophoblast cell line BeWo, The 2nd world congress on reproductive biology, 9-12 October 2011, Cairns, Australia. 2011.


Researcher : Lam YFE

List of Research Outputs

Lam Y.F.E., Lee C.L., Yeung W.S.B. and Chiu C.N., The immunomodulatory properties of glycodelin-A on human monocyte and macrophage., In: Society for the Study of Reproduction., 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A, JUL 31-AUG 4.. U.S.A, 2011.


Researcher : Lam YH

Project Title:11th World Congress on Ultrasound in Obstetrics and Gynecology Integrated First and Second Trimester Screening for Down Syndrome
Investigator(s):Lam YH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2001




Researcher : Lao TTH

Project Title:The First Congress on Obstetrics, Gynecology & Infertility Does Impaired Glucose Tolerance Impact on Pregnancy Outcome?
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/1999


Project Title:Dietary caloric intake and the development of gestational diabetes mellitus in at-risk Chinese women
Investigator(s):Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:The role of adiponectin in the development of gestational diabetes mellitus and its effect on pregnancy outcome
Investigator(s):Lao TTH, Lam KSL, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Elevated TNF-α in gestational diabetes mellitus-cause or consequence?
Investigator(s):Lao TTH, Leung WC, Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The relationship between the antioxidant defense system with the development of gestational diabetes mellitus and its complications in the Chinese population.
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2005




Researcher : Lau ETK

List of Research Outputs

Au P.K., Kwok Y.K., Leung K.Y., Tang L.Y., Tang M.H.Y. and Lau E.T.K., Detection of the S252W mutation in fibroblast growth factor receptor 2 (FGFR2) in fetal DNA from maternal plasma in a pregnancy affected by Apert syndrome, Prenatal Diagnosis. 2011, 31: 218-220.
Chen E.Z., Chiu R.W., Sun H., Akolekar R., Chan K.C., Leung T.Y., Jiang P., Zheng Y.W., Lun F.M., Chan L.Y., Jin Y., Go A.T., Lau E.T.K., To W.W.K., Leung W.C., Tang R.Y., Au-Yeung S.K., Lam H., Kung Y.Y., Zhang X., van Vugt J.M., Minekawa R., Tang M.H.Y., Wang J., Oudejans C.B., Lau T.K., Nicolaides K.H. and Lo Y.M., Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing, PLoS One. 2011, 6: e21791.
Chiu R.W., Akolekar R., Zheng Y.W., Leung T.Y., Sun H., Chan K.C., Lun F.M., Go A.T., Lau E.T.K., To W.W.K., Leung W.C., Tang R.Y., Au-Yeung S.K., Lam H., Kung Y.Y., Zhang X., ean Vugt J.M., Minekawa R., Tang M.H., Wang J., Oudejans C.B., Lau T.K., Nicolaides K.H. and Lo Y.M., Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study, British Medical Journal. 2011, 342: c7401.
Chung B.H.Y., Cheuk D.K.L., Tang M.H.Y., Lau E.T.K., Chan Y.K. and Lau Y.L., Disclosing Results of Autism Genomic Testing-Systematic Review and Applying Its Results to Clinical Practice, International Meeting for Autism Research (IMFAR), Toronto, Ontario, Canada, 17-19 May 2012. 29.
Ho A., Liu A.P.Y., Lun K.S., Tam T., Chan K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., 17p13.3 Class I Microduplication in a Newborn with Microcephaly, Aortic Stenosis and Dysmorphic Facial Features, Hong Kong Journal of Paediatrics (new series). Proceedings of Congress of Joint Annual Scientific Meeting 2011, The Hong Kong Paediatric Society and American Academy Pediatrics in conjunction with Hong Kong Paediatric Nurses Association, 4-5 June 2011. 2011, 16(3): 216.
Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.
Lau E.T.K., Evaluation of aCGH for Prenatal Diagnosis., The 3rd Prenatal Diagnosis Conference, Quangzhou. November 5, 2011, Quangzhou, China.. 2011.
Lau E.T.K., Evaluation of aCGH for Prenatal Diagnosis, Roche Applied Science 2011 User Conference. November 3, 2011, Hong Kong.. 2011.
Lau E.T.K., Findings on Prenatal aCGH evaluation, The 33rd Fetoscopy Working Group Meeting. September 10, 2011, Hong Kong. 2011.
Lau E.T.K., Prenatal Diagnostic Service – Present, 30 years of Medical Genetics in Hong Kong. November 19, 2011, Hong Kong . 2011.
Lau E.T.K., Update on Basic Science or Lab Technique - Array CGH for Prenatal Diagnosis, Department of Obstetrics and Gynaecology, The University of Hong Kong, January 16, 2012, Hong Kong. . 2012.
Liu A.P.Y., Ng Y.K., Hui P.W., Lau E.T.K., Tang M.H.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2011, 16: 188.
Liu A.P.Y., Ho A., Yung T.C., Tam T., Chan K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., Inverted Duplication 18q12.1-q22, Hong Kong Journal of Paediatrics (new series). Proceedings of Congress of Joint Annual Scientific Meeting 2011, The Hong Kong Paediatric Society and American Academy Pediatrics in conjunction with Hong Kong Paediatric Nurses Association, 4-5 June 2011. 215, 2011, 16(3).


Researcher : Lee CKF

Project Title:Functional characterization of VAD1.3, a novel acrosome-specific protein by conditional tissue-specific gene inactivation
Investigator(s):Lee CKF, Cheah KSE, Yeung WSB, Luk JMC, Lee NPY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006


Project Title:Environmental Screening, Computational and Biological Characterization of Endocrine Disruptors, in Respect to Receptor Binding, Embryo and Gonad Physiology
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2009


Project Title:Role(s) of Glycodelin on Implantation
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2011


Project Title:The 44th Annual Meeting of Society for the Study of Reproduction Suppression of Olfactomedin-1 (Olfm-1) in Fallopian tube and activation of Wnt-sginaling pathway enhances tubal ectopic pregnancy
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2011
Completion Date:08/2011


Project Title:Study of Electroacupuncture on modulating rodent spermatogenesis after scrotal heat treatment
Investigator(s):Lee CKF, Yeung WSB, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2012


List of Research Outputs

Cao S., Yeung W.S.B. and Lee C.K.F., Functional Study of an Acrosome-Expressing Gene, VAD1.2 in Mice Spermatogenesis. P.583, The 44th Annual Meeting. Society for the Study of Reproduction. July 31 – Aug 4, 2011, Portland, Oregon . 2011.
Cao S.B., Yeung W.S.B. and Lee C.K.F., Functional study of VAD1.2 deficiency on spermatogenesis in mice. O.2.01., The 16th Research Postgraduate Symposium, HKU. December 7-8, 2011, Hong Kong.. 2011.
Chai J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Ovarian stimulation modulates steroid receptor expression and spheroid attachment in peri-implantation endometria: studies on natural and stimulated cycles, Fertility Sterility. 2011, 96(3): 764-768.
Chen C.H., Lee Y.L., Lee C.K.F. and Yeung W.S.B., Role of MicroRNAs in reprogramming of somatic cells into induced pluripotent stem cells. P.1.01, The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong. 2011.
Chen C.H., Lee Y.L., Lee C.K.F. and Yeung W.S.B., Role of microRNAs in reprogramming of somatic cells into induced pluripotent stem cells. P.01., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Cheong A.W.Y., Liu W.M., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., MiR-let-7a regulates integrin-b3 expression and modulates mouse blastocyst attachment in vitro. P.02. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Cheong A.W.Y., Liu W.M., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Role of MicroRNA Let-7 in the implantation of mouse blastocyst. P.1.02, The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.
Cheung T.Y., Tsang H., Wong C.K., Yeung W.S.B. and Lee C.K.F., The endocrine disruptive chemical bispenol modulates Wnt-signaling for spheroid attachment onto endometrial cells. P.03. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction, Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Gao J., Zuo Y., So K.H., Yeung W.S.B., Ng E.H.Y. and Lee C.K.F., Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. , Spermatogenesis . 2012, 2(1): 53-62.
Gao J., Zuo Y., Yeung W.S.B. and Lee C.K.F., Potential role of VAD1.3 in spermatogenesis and fertilization. O.2.05. , The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.
Kodithuwakkul S.P., Pang R.T.K., Ng E.H.Y., Cheung A.N.Y., Horne A.W., Ho P.C., Yeung W.S.B. and Lee C.K.F., Wnt activation downregulates Olfactomedin-1 (Olfm-1) in Fallopian tubal epithelial cells: an microenvironment predisposed to tubal ectopic pregnancy, Laboratory Investigation . 2012, 92: 256-264.
Lam K.K., Lee C.L., Lee C.K.F., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A interacts with siglec-6 to suppress trophoblast invasion. P.08., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Lee C.K.F., Ovarian Stimulation: Effects on endometrial receptivity and implantation. The Hong Kong Sanatorium & Hospital, 19 Jan 2012, Hong Kong., 2012.
Lee C.L., Chiu C.N., Pang P.C., Chu I.K., Lee C.K.F., Koistinen R., Koistinen H., Seppala M., Morris H.R., Tissot B., Panico M., Dell A. and Yeung W.S.B., HKU Strategic Research Areas & Themes “Reproduction and Development” Best Research Output Award 2011 (2nd Prize): Glycosylation failure extends to glycoproteins in gestational diabetes: Evidence from reduced alpha 2-6 sialylation and impaired immunomodulatory activities of pregnancy-related glycodelin-A. Diabetes. 2011;60(3):909-17., HKU Strategic Research Areas & Themes “Reproduction and Development”. 2011.
Lin X., Song J., Shaw P.C., Ng T.B., Sze C.W., Tong Y., Lee C.K.F. and Zhang Y., An Autoimmunized Mouse Model Recapitulates Key Features in the Pathogenesis of SjÖgren’s Syndrome, In: Lin X, Song JX, Shaw PC, Ng TB, Stephen Sze CW, Tong Y, Lee KF, Kalin Zhang YB., International Immunology. 2011 Oct, 23(10): 613-24.. 2011, 23: 613-24.
Liu W., Pang R.T.K., Cheong A.W.Y., Lee C.K.F. and Yeung W.S.B., Excellent Poster Presentation: Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, 2nd SKLRB Symposia on “Frontiers in Reproductive Biology. 2012.
Liu W., Pang R.T.K., Cheong A.W.Y., Ng E.H.Y., Lao K., Lee C.K.F. and Yeung W.S.B., Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, PLoS One. 2012, 7(5): 1-12.
Liu W., Pang R.T.K., Chiu C.N., Wong B.P.C., Lao K., Lee C.K.F. and Yeung W.S.B., Sperm-borne microRNA-34c is required for the first cleavage division in mouse, PNAS. 2012, 109: 490-4.
Pang R.T.K., Lam K.W., Lee C.K.F., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclise activation elevates miR-34a and suppresses invasion in the trophoblast cell line BeWo, The 2nd world congress on reproductive biology, 9-12 October 2011, Cairns, Australia. 2011.
Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., miR-135A regulates preimplantation embryo development through down-regulation of E3 Ubiquitin Ligase Seven In Absentia Homolog 1A (SIAH1A) expression. , In: Pang RT, Liu WM, Leung CO, Ye TM, Kwan PC, Lee KF, Yeung WS. , Plos one. 2011, 6: e27878.
So K.H., Lee C.L., Yeung W.S.B. and Lee C.K.F., Glycodelin suppresses endometrial cell migration and invasion but stimulates spheroid attachment. , Reprod Biomed Online . 2012, 24(6): 639-45.
Tsang H., Cheung T.Y., Kodithuwakku K.S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. , Reprod Toxicol . 2012, 33: 60-66.
Zhang Y., Sze C.W., Tong Y., Song J., Lee C.K.F., Leung G.P.H., Ng T.B. and Shaw P.C., Anti-parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models. , In: Song JX, Stephen Sze CW, Ng TB, Caivin Lee KF, George Leung PH, Shaw PC, Tong Y, Zhang YB*., Journal of Ethnopharmacology. 2012 Feb 15; 139(3): 698-711. . 2012, 139: 698-711.
Zhang Y., Sze C.W., Tong Y., Cai Y., Liu J., Lee C.K.F. and Leung G.P.H., Comparative Analysis of Caffeoylquinic Acids and Lignans in Roots and Seeds among Various Burdock (Arctium lappa) Genotypes with High Antioxidant Activity., In: Liu JY, Cai YZ, Wong RNS, Lee KF, Tang CY, Sze CW, Tong Y and Zhang YB*. , J Agri Food Chem. 2012 April, 60 (16): 4067–75. . 2012, 60: 4067–75.


Researcher : Lee CL

Project Title:Differential effects of glycodelin-A on human T-helper cell subsets: A mechanism producing an immune privilege environment for fetal development
Investigator(s):Lee CL, Chiu CN, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2010
Completion Date:02/2012


List of Research Outputs

Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophage promoted the colony forming ability of putative endometrial stromal stem cells, Days of Molecular Medicine 2012, 10-12 November 2011, Hong Kong. 2011.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophages Increased the Colony Forming Activity of Putative Endometrial and Endometriotic Stromal Stem Cells, World Congress for Endometriosis. 2011.
Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Lam Y.F.E., Lee C.L., Yeung W.S.B. and Chiu C.N., The immunomodulatory properties of glycodelin-A on human monocyte and macrophage., In: Society for the Study of Reproduction., 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A, JUL 31-AUG 4.. U.S.A, 2011.
Lee C.L., Chiu C.N., Pang P.C., Chu I.K., Lee C.K.F., Koistinen R., Koistinen H., Seppala M., Morris H.R., Tissot B., Panico M., Dell A. and Yeung W.S.B., HKU Strategic Research Areas & Themes “Reproduction and Development” Best Research Output Award 2011 (2nd Prize): Glycosylation failure extends to glycoproteins in gestational diabetes: Evidence from reduced alpha 2-6 sialylation and impaired immunomodulatory activities of pregnancy-related glycodelin-A. Diabetes. 2011;60(3):909-17., HKU Strategic Research Areas & Themes “Reproduction and Development”. 2011.
Pang P.C., Chiu C.N., Lee C.L., Chang L.Y., Panico M., Morris H.R., Haslam S.M., Khoo K.H., Clark G.F., Yeung W.S.B. and Dell A., Faculty of 1000 “Naturally Selected” on December 2011: Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida. Science. 2011;333(6050):1761-4. , Faculty of 1000. 2011.
Pang P.C., Chiu C.N., Lee C.L., Chang L.Y., Panico M., Morris H.R., Haslam S.M., Khoo K.H., Clark G.F., Yeung W.S.B. and Dell A., Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida., Science. 2011, 333: 1761-4.
Pang R.T.K., Lam K.W., Lee C.L., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclase activation elevates MiR-34A and suppresses invasion in the trophoblast cell line BeWo., World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
So K.H., Lee C.L., Yeung W.S.B. and Lee C.K.F., Glycodelin suppresses endometrial cell migration and invasion but stimulates spheroid attachment. , Reprod Biomed Online . 2012, 24(6): 639-45.


Researcher : Lee CP

List of Research Outputs

Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.


Researcher : Lee CYL

List of Research Outputs

Chong T.Y.I., Chan C.Y., Lee C.Y.L., Shiu S.Y.W., Li J.Y.H. and Yao K.M., Establishing a Cell-based Platform to identify Molecules for Directing the Differentiation of Human Embryonic Stem Cells into Insulin-secreting β-like cells, 2012 Hong Kong Inter-University Postgraduate Symposium on Life Science, The Hong Kong University of Science and Technology, 9 June 2012.
Xin M., Lee C.Y.L., Yeung W.S.B. and Ho P.C., The Expression and Role of Adamts9 during Human Embryonic Stem Cell Differentiation, 1st annual Cambridge Stem Cell international symposium . 2011.


Researcher : Lee VCY

List of Research Outputs

Lee V.C.Y., Tang F.O.S., Ng E.H.Y., Yeung W.S.B. and Ho P.C., A prospective double-blinded, randomized, placebo-controlled trial on the use of letrozole pretreatment with misoprostol for second-trimester medical abortion, Contraception 2011. 2011, 84(6): 628-33.
Lee V.C.Y., Yung S.F., Li R.H.W., Watzer B., Schweer H., Ng E.H.Y. and Ho P.C., A randomized comparison of pharmacokinetics of a single vaginal dose of dry misoprostol or misoprostol moistened with normal saline or with acetic acid, Human Reproduction. 2011, 26(11): 2981-7.
Yeung T.W.Y., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., HKCOG guidelines: induction of ovulation, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Jan/Feb: 5-31.


Researcher : Leung CY

List of Research Outputs

Liu S., Chan Y.K., Leung C.Y., Jiang L., Luk M.H.M., Lo S.T.S., Fong D.Y.T., Cheung A.N.Y., Lin Z.Q. and Ngan H.Y.S., HPV16 and HPV58 integrations in cervical cancer and premalignant lesions, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22. 2011.
Ngan H.Y.S., Liu S., Leung C.Y. and Cheung A.N.Y., Association between DeltaNp73 expression and HPV infection in cervical cancer, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22, . 2011.


Researcher : Leung KY

List of Research Outputs

Au P.K., Kwok Y.K., Leung K.Y., Tang L.Y., Tang M.H.Y. and Lau E.T.K., Detection of the S252W mutation in fibroblast growth factor receptor 2 (FGFR2) in fetal DNA from maternal plasma in a pregnancy affected by Apert syndrome, Prenatal Diagnosis. 2011, 31: 218-220.
Cheung V.Y.T., Yang F. and Leung K.Y., 2D versus 3D transabdominal sonography for the measurement of lower uterine segment thickness in women with previous cesarean delivery. , Int J Gynaecol Obstet. 2011 Sep;114(3):234-7. Epub 2011 Jul 2. . 2011, 114: 234-7.
Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.
Yuan Y., Leung K.Y., Ouyang Y.S., Yang F., Tang M.H.Y., Chau A.K. and Dai Q., Simultaneous real-time imaging of four-chamber and left ventricular outflow tract views using xPlane imaging capability of a matrix array probe, Ultrasound Obstetrics and Gynecology. 2011, 37: 302-309.


Researcher : Leung LY

List of Research Outputs

Chan D.W., Liu V.W.S., Leung L.Y., Yao K.M., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells, J Pathol. 2011, 225(4): 525-34.


Researcher : Leung ON

List of Research Outputs

Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Leung O.N., Pang R.T.K., Ye T., Cheung A.N.Y. and Yeung W.S.B., MiR-135a involves in the formation of tumor-initiating cells in cervical cancer. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.
Pang R.T.K., Lam K.W., Lee C.L., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclase activation elevates MiR-34A and suppresses invasion in the trophoblast cell line BeWo., World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Pang R.T.K., Lam K.W., Lee C.K.F., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclise activation elevates miR-34a and suppresses invasion in the trophoblast cell line BeWo, The 2nd world congress on reproductive biology, 9-12 October 2011, Cairns, Australia. 2011.
Ye T., Pang R.T.K., Leung O.N., Kwan C.K. and Yeung W.S.B., Comparison of early embryo attachment under atmospheric condition and oxygen tension on a three-dimensional endometrium-blastocyst implantation model, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.


Researcher : Leung ON

List of Research Outputs

Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Leung O.N., Pang R.T.K., Ye T., Cheung A.N.Y. and Yeung W.S.B., MiR-135a involves in the formation of tumor-initiating cells in cervical cancer. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.
Pang R.T.K., Lam K.W., Lee C.L., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclase activation elevates MiR-34A and suppresses invasion in the trophoblast cell line BeWo., World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Pang R.T.K., Lam K.W., Lee C.K.F., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclise activation elevates miR-34a and suppresses invasion in the trophoblast cell line BeWo, The 2nd world congress on reproductive biology, 9-12 October 2011, Cairns, Australia. 2011.
Ye T., Pang R.T.K., Leung O.N., Kwan C.K. and Yeung W.S.B., Comparison of early embryo attachment under atmospheric condition and oxygen tension on a three-dimensional endometrium-blastocyst implantation model, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.


Researcher : Leung THY

Project Title:Identification and characterization of cancer stem cells in cervical cancer
Investigator(s):Leung THY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2011


List of Research Outputs

Fung K.C.F., Chan D.W., Liu V.W.S., Leung T.H.Y., Cheung A.N.Y. and Ngan H.Y.S., Increased expression of PITX2 transcription factor contributes to ovarian cancer progression, PLos One. PLos, 2012, 7: e37076.
Leung T.H.Y., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., Indetification and characterization of cancer stem-like cells in cervical cancer, , Asia-Oceania Research Organization in Genital Infection and Neoplasia (AOGIN) 2012, Hong Kong. 2012.
Leung T.H.Y., Wong S.C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., Significance of p73 in the sensitivity of cancer treatment in gynaecological cancers, Tumor Microenvironment-New Concepts and Molecular Mechanisms, Croucher Advanced Study Institute 2012, Hong Kong. 2012.
Lok T.M., Chan D.W., Liu V.W.S., Hui W.Y., Leung T.H.Y., Yao K.M. and Ngan H.Y.S., Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells, PLoS One. 2011, 6: e23790.


Researcher : Leung TW

List of Research Outputs

Leung T.W., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Methylation at HPV18 E2 binding sites increases during cervical carcinogenesis, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22. 2011.


Researcher : Leung WC

List of Research Outputs

Chan E.K.L., Brownridge D.A., Tiwari A.F.Y., Fong D.Y.T., Leung W.C. and Ho P.C., Associating pregnancy with partner violence against Chinese women, Journal of Interpersonal Violence. 2011, 26(7): 1478-1500.
Chan E.K.L., Brownridge D.A., Fong D.Y.T., Tiwari A.F.Y., Leung W.C. and Ho P.C., Violence against pregnant women can increase the risk of child abuse: A longitudinal study, Child Abuse & Neglect. 2012, 36(4): 275-284.
Chen E.Z., Chiu R.W., Sun H., Akolekar R., Chan K.C., Leung T.Y., Jiang P., Zheng Y.W., Lun F.M., Chan L.Y., Jin Y., Go A.T., Lau E.T.K., To W.W.K., Leung W.C., Tang R.Y., Au-Yeung S.K., Lam H., Kung Y.Y., Zhang X., van Vugt J.M., Minekawa R., Tang M.H.Y., Wang J., Oudejans C.B., Lau T.K., Nicolaides K.H. and Lo Y.M., Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing, PLoS One. 2011, 6: e21791.
Chiu R.W., Akolekar R., Zheng Y.W., Leung T.Y., Sun H., Chan K.C., Lun F.M., Go A.T., Lau E.T.K., To W.W.K., Leung W.C., Tang R.Y., Au-Yeung S.K., Lam H., Kung Y.Y., Zhang X., ean Vugt J.M., Minekawa R., Tang M.H., Wang J., Oudejans C.B., Lau T.K., Nicolaides K.H. and Lo Y.M., Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study, British Medical Journal. 2011, 342: c7401.
Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.


Researcher : Li C

List of Research Outputs

Li C., Liu V.W.S., Chan D.W., Yao K.M. and Ngan H.Y.S., LY294002 and Metformin Cooperatively Enhance the Inhibition of Growth and the Induction of Apoptosis of Ovarian Cancer Cells., Int J Gynecol Cancer.. 2011, 22: 15-22.


Researcher : Li ICF

List of Research Outputs

Chai J., Hon E., Li I.C.F., Pun T.C., Yeung W.S.B. and Ho P.C., A pilot study of pre-operative misoprostol in reducing operative blood loss during hysterectomy, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2011, 158(1): 72-5.


Researcher : Li RHW

List of Research Outputs

Lee V.C.Y., Yung S.F., Li R.H.W., Watzer B., Schweer H., Ng E.H.Y. and Ho P.C., A randomized comparison of pharmacokinetics of a single vaginal dose of dry misoprostol or misoprostol moistened with normal saline or with acetic acid, Human Reproduction. 2011, 26(11): 2981-7.
Li R.H.W., Ng E.H.Y. and Ho P.C., Polycystic Ovary Syndrome and Infertility, In: Editors: Jaideep Malhotra, Rohana Haththotuwa, Jaydeep D Tank, Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings) - Asia and Oceania Federation of Obstetrics and Gynaecology. 2011, Chapter 11: 105-111.
Li R.H.W., Wong C.Y.G., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Response to letter to the editor: Serum anti-Mullerian hormone level is not altered in women using hormonal contraceptives, Contraception. 2011, 85(5): 520-521.
Liao S., Li R.H.W., Ho J.C.M., Yeung W.S.B., Ng E.H.Y., Cheung A.N.Y., Tang F. and O W.S., Possible role of adrenomedullin in the pathogenesis of tubal ectopic pregnancy, Journal of Clinical Endocrinology and Metabolism . Journal of Clinical Endocrinolog and Metabolism, 2012, 97: 2105-2112.
O W.S., Liao S., Li R.H.W., Ho J.C.M., Ng E.H.Y., Yeung W.S.B., Cheung A.N.Y. and Tang F., The role of adrenomedullin in tubal ectopic pregnancy, World Congress on Reproductive Biology Abstracts, Cairns, Australia. 2011, 81 Abstract 124.
Yeung T.W.Y., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., HKCOG guidelines: induction of ovulation, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Jan/Feb: 5-31.


Researcher : Li TKT

List of Research Outputs

Cheung C., Tai J., Cheng V. and Li T.K.T., Impact of timing and choice of antibiotic prophylaxis on Cesarean section surgical site infection in a Hong Kong teaching hospital, The 5th International Congress of the Asia Pacific Society of Infection Control in Melbourne, 8th – 11th November, 2011, Melbourne, Australia.. 2011.


Researcher : Liu S

List of Research Outputs

Leung T.W., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Methylation at HPV18 E2 binding sites increases during cervical carcinogenesis, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22. 2011.
Liu S., HPV and cervical cancer, 10th International Conference of the Asian Clinical Oncology Society, Seoul, Korea. 2012.
Liu S., Chan Y.K., Leung C.Y., Jiang L., Luk M.H.M., Lo S.T.S., Fong D.Y.T., Cheung A.N.Y., Lin Z.Q. and Ngan H.Y.S., HPV16 and HPV58 integrations in cervical cancer and premalignant lesions, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22. 2011.
Ngan H.Y.S., Liu S., Leung C.Y. and Cheung A.N.Y., Association between DeltaNp73 expression and HPV infection in cervical cancer, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22, . 2011.
Wei N., Liu S., Chan K.K.L. and Ngan H.Y.S., Tumour Suppressive Function and Modulation of Programmed Cell Death 4 (PDCD4) in Ovarian Cancer, PLoS One. 2012.
Wong G.W., Lo C.K., Chow N.K., Tsun O.K.L., Szeto E., Liu S., Ngan H.Y.S. and Cheung A.N.Y., Comparison of the GenoFlow human papillomavirus (HPV) test and the Linear Array assay for HPV screening in an Asian population., J Clin Microbiol.. 2012, 50(5): 1691-7.


Researcher : Liu VWS

List of Research Outputs

Chan D.W., Liu V.W.S., Leung L.Y., Yao K.M., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells, J Pathol. 2011, 225(4): 525-34.
Fung K.C.F., Chan D.W., Liu V.W.S., Leung T.H.Y., Cheung A.N.Y. and Ngan H.Y.S., Increased expression of PITX2 transcription factor contributes to ovarian cancer progression, PLos One. PLos, 2012, 7: e37076.
Li C., Liu V.W.S., Chan D.W., Yao K.M. and Ngan H.Y.S., LY294002 and Metformin Cooperatively Enhance the Inhibition of Growth and the Induction of Apoptosis of Ovarian Cancer Cells., Int J Gynecol Cancer.. 2011, 22: 15-22.
Lok T.M., Chan D.W., Liu V.W.S., Hui W.Y., Leung T.H.Y., Yao K.M. and Ngan H.Y.S., Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells, PLoS One. 2011, 6: e23790.


Researcher : Liu W

Project Title:World Congress on Reproductive Biology Involvement of let-7 microRNA in the regulation of embryo implantation in mice
Investigator(s):Liu W
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2011


List of Research Outputs

Liu W., Pang R.T.K., Cheong A.W.Y., Lee C.K.F. and Yeung W.S.B., Excellent Poster Presentation: Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, 2nd SKLRB Symposia on “Frontiers in Reproductive Biology. 2012.
Liu W., Pang R.T.K., Cheong A.W.Y., Ng E.H.Y., Lao K., Lee C.K.F. and Yeung W.S.B., Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, PLoS One. 2012, 7(5): 1-12.
Liu W., Pang R.T.K., Chiu C.N., Wong B.P.C., Lao K., Lee C.K.F. and Yeung W.S.B., Sperm-borne microRNA-34c is required for the first cleavage division in mouse, PNAS. 2012, 109: 490-4.
Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., miR-135A regulates preimplantation embryo development through down-regulation of E3 Ubiquitin Ligase Seven In Absentia Homolog 1A (SIAH1A) expression. , In: Pang RT, Liu WM, Leung CO, Ye TM, Kwan PC, Lee KF, Yeung WS. , Plos one. 2011, 6: e27878.


Researcher : Liu X

List of Research Outputs

Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of miR-199b-5p is associated with chemoresistance via Jagged 1 in human ovarian cancer, 18th Hong Kong International Cancer Congress 2011.
Liu X., Chan D.W. and Ngan H.Y.S., Mechanisms of Chemoresistance in Human Ovarian Cancer at a Glance, Gynecology & Obstetrics. 2012, 2: 1000e104.


Researcher : Lok TM

List of Research Outputs

Lok T.M., Chan D.W., Liu V.W.S., Hui W.Y., Leung T.H.Y., Yao K.M. and Ngan H.Y.S., Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells, PLoS One. 2011, 6: e23790.


Researcher : Lu X

List of Research Outputs

Jiang L., Siu M.K., Wong O.G., Tam K.F., Lu X., Lam E.W., Ngan H.Y.S., Le X.F., Wong E.S., Monteiro L.J., Chan H.Y. and Cheung A.N.Y., iASPP and chemoresistance in ovarian cancers: effects on paclitaxel-mediated mitotic catastrophe, Clinical Cancer Research. 2011, 17(21): 6924-33.


Researcher : Mak SL

List of Research Outputs

Mak S.L., Chan D.W. and Ngan H.Y.S., Functional characterization of Has-miR-141, a putative oncogene in promoting anchorage-independent growth ability of ovarian cancer cells, 18th Hong Kong International Cancer Congress 2011.
Mak S.L., Chan D.W. and Ngan H.Y.S., miR-141 confers anoikis resistance of ovarian cancer cells by targeting KLF12, AACR Annual Meeting 2012, Chicago, IL, USA. 2012.


Researcher : Ng EHY

Project Title:The 17th IFFS World Congress on Fertility and Sterility 1) Measurement of Serum CA-125 Concentrations Does not Improve the Value of Chlamydia Trachomatis Antibody (CAT) in Predicting Tubal Pathology at Laparoscopy 2) A Comparison of the Pain Levels During Egg Collection and Postoperative Side Effects Using Paracervical Block with and without Conscious Sedation
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2001


Project Title:Comparison of the prevalence of polycystic ovary only and polycystic ovary syndrome between two different ethnic populations
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:The role of anti-Müllerian hormone in the prediction of livebirth rate and cumulative livebirth rate during in vitro fertilization treatment
Investigator(s):Ng EHY, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2006


Project Title:A randomized controlled trial on the effect of dehydroepiandrosterone (DHEA) supplementation on ovarian reserve markers, response to a standard low dose FSH stimulation and IVF cycle outcomes in patients with normal and poor ovarian reserve
Investigator(s):Ng EHY, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:10/2010
Completion Date:09/2011


Project Title:27th Annual meeting of European Society of Human Reproduction and Embryology Effect of non-invasive acupuncture on the pregnancy outcome of IVF treatment— A randomized controlled study
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2011
Completion Date:07/2011


Project Title:Role of Sirt1 in generation of mouse induced pluripotent stem cells
Investigator(s):Ng EHY, Lee CKF, Lee CYL, Ng RK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Mechanisms of delayed ovulation following Ulipristal used as emergency contraception
Investigator(s):Ng EHY, Li RHW, O WS, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2012


List of Research Outputs

Chai J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Ovarian stimulation modulates steroid receptor expression and spheroid attachment in peri-implantation endometria: studies on natural and stimulated cycles, Fertility Sterility. 2011, 96(3): 764-768.
Chan C.H.Y., Chan C.L.W., Ng E.H.Y., Ho P.C., Chan T.H.Y., Lee G.L. and Hui W.H.C., Incorporating spirituality in psychosocial group intervention for women undergoing in vitro fertilization: A prospective randomized controlled study, Psychology and Psychotherapy: Theory, Research and Practice. 2011, 2011: 1-18.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophage promoted the colony forming ability of putative endometrial stromal stem cells, Days of Molecular Medicine 2012, 10-12 November 2011, Hong Kong. 2011.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophages Increased the Colony Forming Activity of Putative Endometrial and Endometriotic Stromal Stem Cells, World Congress for Endometriosis. 2011.
Gao J., Zuo Y., So K.H., Yeung W.S.B., Ng E.H.Y. and Lee C.K.F., Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. , Spermatogenesis . 2012, 2(1): 53-62.
Ko K.Y.J., Wan H.L., Ngu S.F., Cheung V.Y.T. and Ng E.H.Y., Cesarean scar molar pregnancy, Obstet Gynecol. 2012, 119(2 Pt 2): 449-51.
Kodithuwakkul S.P., Pang R.T.K., Ng E.H.Y., Cheung A.N.Y., Horne A.W., Ho P.C., Yeung W.S.B. and Lee C.K.F., Wnt activation downregulates Olfactomedin-1 (Olfm-1) in Fallopian tubal epithelial cells: an microenvironment predisposed to tubal ectopic pregnancy, Laboratory Investigation . 2012, 92: 256-264.
Lee V.C., Chan C.C.W., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Sequential use of letrozole and gonadotrophin in women with poor ovarian reserve: a randomized controlled trial, Reproductive BioMedicine Online 2011. 2011, 23(3): 380-8.
Lee V.C.Y., Tang F.O.S., Ng E.H.Y., Yeung W.S.B. and Ho P.C., A prospective double-blinded, randomized, placebo-controlled trial on the use of letrozole pretreatment with misoprostol for second-trimester medical abortion, Contraception 2011. 2011, 84(6): 628-33.
Lee V.C.Y., Yung S.F., Li R.H.W., Watzer B., Schweer H., Ng E.H.Y. and Ho P.C., A randomized comparison of pharmacokinetics of a single vaginal dose of dry misoprostol or misoprostol moistened with normal saline or with acetic acid, Human Reproduction. 2011, 26(11): 2981-7.
Li H.W., Anderson R.A., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Evaluation of serum antimullerian hormone and inhibin B concentrations in the differential diagnosis of secondary oligoamenorrhea, Fertility and Sterility 2011. 2011, 96(3): 774-9.
Li H.W.R., Gebbie A.E., Wong R.W.S., Ng E.H.Y., Glasier A.F. and Ho P.C., The use of sex hormones in women with rheumatological diseases, Hong Kong Medical Journal. 2011, 17: 1-5.
Li R.H.W., Ng E.H.Y. and Ho P.C., Polycystic Ovary Syndrome and Infertility, In: Editors: Jaideep Malhotra, Rohana Haththotuwa, Jaydeep D Tank, Handbook on Managing Infertility (Meeting the Challenges in Low-Resource Settings) - Asia and Oceania Federation of Obstetrics and Gynaecology. 2011, Chapter 11: 105-111.
Li R.H.W., Wong C.Y.G., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Response to letter to the editor: Serum anti-Mullerian hormone level is not altered in women using hormonal contraceptives, Contraception. 2011, 85(5): 520-521.
Li Y., Ng E.H.Y., Stener-Victorin E., Hou L., Wu T., Han F. and Wu X., Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis, Fertility and Sterility. 2011, 96: 452-458.
Liao S., Li R.H.W., Ho J.C.M., Yeung W.S.B., Ng E.H.Y., Cheung A.N.Y., Tang F. and O W.S., Possible role of adrenomedullin in the pathogenesis of tubal ectopic pregnancy, Journal of Clinical Endocrinology and Metabolism . Journal of Clinical Endocrinolog and Metabolism, 2012, 97: 2105-2112.
Liu W., Pang R.T.K., Cheong A.W.Y., Ng E.H.Y., Lao K., Lee C.K.F. and Yeung W.S.B., Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, PLoS One. 2012, 7(5): 1-12.
Ng E.H.Y., "中醫生殖軸理論在多囊卵巢綜合征和輔助生殖中的轉化應用與發展”. 2011.
Ng E.H.Y., (2011) Changes in endometrial vascularity during IVF treatment, The XXII Asian & Oceanic Congress of Obstetrics & Gynaecology organized by Asian & Oceanic Federation of Obstetrics & Gynaecology, Taiwan, 23-27 September 2011. 2011.
Ng E.H.Y., (2011) Evidence-based approach of subfertile patients, 廣東省醫學會生殖醫學分會第一屆學術會議 organized by Guangdong Medical Association, Guangzhou, China, 16-17 July 2011 . 2011.
Ng E.H.Y., (2011) Preimplantation genetic diagnosis for thalassaemias, The 33rd Fetoscopy Working Group meeting, Hong Kong, 8-11, September 2011 . 2011.
Ng E.H.Y., (2011) Ultrasound for ovarian reserve and ovarian response, The first seminar workshop in OB-GYN ultrasound organized by Asian & Oceanic Federation of Obstetrics & Gynaecology and Philippine Society of ultrasound in Obstetrics and Gynecology, Manila, Philippine, 12 January 2012. . 2012.
Ng E.H.Y., (2011) Use of three-dimensional ultrasound in reproductive medicine , The 1st Conference on reproductive medicine organized by Army Hospitals of China, Guilin, China, 2-4 December 2011. 2011.
Ng E.H.Y., (2011) Uterine and endometrial factors of repeated IVF failures, The 4th International Seminar on repeated IVF-ET failure organized by Southern Medical University, Guangzhou, China, 11-13 November 2011. 2011.
Ng E.H.Y., Clinical trial: design, implementation and quality control in the acupuncture study for women with polycystic ovary syndrome., Implementation meeting of the project “A national multi-centre randomized controlled trial of acupuncture / clomiphene in polycystic ovary syndrome’ organized by Department of Obstetrics and Gynaecology, Heilongjiang University of Chinese Medicine, Harbin, China, 19-20 August 2011. 2011.
Ng E.H.Y., Screening visit and consent, Implementation meeting of the project “A national multi-centre randomized controlled trial of acupuncture/clomiphene in polycystic ovary syndrome" organized by Department of Obstetrics and Gynaecology, Heilongjiang University of Chinese Medicine, Beijing, China, 09-10 June 2012. 2012.
Ng E.H.Y., The role and use of AMH in reproductive medicine. , The 15th World Congress on Gynecological Endocrinology organized by International Society of Gynecological Endocrinology, Florence, Italy, 7-10 March, 2012. (Plenary session) . 2012.
Ng E.H.Y., Treatment visits and end of visits, Implementation meeting of the project “A national multi-centre randomized controlled trial of acupuncture/clomiphene in polycystic ovary syndrome’ organized by Department of Obstetrics and Gynaecology, Heilongjiang University of Chinese Medicine, Beijing, China, 09-10 June 2012. 2012.
Ng E.H.Y., Ultrasound diagnosis of polycystic ovary syndrome, Implementation meeting of the project “A national multi-centre randomized controlled trial of acupuncture / clomiphene in polycystic ovary syndrome’ organized by Department of Obstetrics and Gynaecology, Heilongjiang University of Chinese Medicine, Beijing, China, 17-18 December 2011. 2011.
Ng E.H.Y., Use of androgens in poor ovarian responders, The Symposium on Reproductive Endocrinology and Clinical Guidelines organized by Guangdong Medical Association, Guangzhou, China, 11-13 May 2012. 2012.
O W.S., Liao S., Li R.H.W., Ho J.C.M., Ng E.H.Y., Yeung W.S.B., Cheung A.N.Y. and Tang F., The role of adrenomedullin in tubal ectopic pregnancy, World Congress on Reproductive Biology Abstracts, Cairns, Australia. 2011, 81 Abstract 124.
Yeung T.W.Y., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., HKCOG guidelines: induction of ovulation, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Jan/Feb: 5-31.


Researcher : Ng TY

Project Title:A propective randomised controlled trial: prevention of lymphedema by omentoplasty after pelvic lymphadenectomy
Investigator(s):Ng TY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Low Budget High Impact Programme
Start Date:11/2001


List of Research Outputs

Kondalsamy-Chennakesavan S., Janda M., Gebski V., Baker J., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K.F., Chan K.K.L., Wrede D.H., Pather S., Simcock B., Farrell R., Robertson G., Walker G., McCartney A. and Obermair A., Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial, Eur J Cancer, Apri 12 . 2012.
Obermair A., Janda M., Baker J., Kondalsamy-Chennakesavan S., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K.F., Chan K.K.L., Wrede D.H., Pather S., Simcock B., Farrell R., Robertson G., Walker G., McCartney A. and Gebski V., Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: results from a randomised controlled trial, Eur J Cancer, 2012 May. 2012, 48(8): 1147-53.


Researcher : Ngai CSW

Project Title:Vaginal misoprostol for first trimester termination of pregnancy prior to 9 weeks of gestation
Investigator(s):Ngai CSW, Tang FOS, Chan YM, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:05/1999


Project Title:Cervical assessment in prediction of preterm labour: is three-dimensional ultrasonography a better choice?
Investigator(s):Ngai CSW, Lao TTH, Chen M, Leung KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Multiple pregnancy and gestational diabetes: a physiological response or a pathologic condition?
Investigator(s):Ngai CSW, Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The XIXth Asian and Oceanic Congress of Obstetrics & Gynaecology Should We Screen Sexually Transmitted Diseases for Women Requesting for Termination of Pregnancy?
Investigator(s):Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2005




Researcher : Ngan HYS

Project Title:High dose cis-platinum and cyclophosphamide vs taxol in ovarian cancer
Investigator(s):Ngan HYS, Wong RLC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:07/1994


Project Title:Functional characterization and clinical significance of C35-DNp73 in ovarian cancer.
Investigator(s):Ngan HYS, Leung THY, Liu S
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2010
Completion Date:02/2012


Project Title:Functional role of DNp73-C35 interaction in chemo-resistance of ovarian cancer.
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2011


Project Title:Functional characterization and clinical significance of DNp73-C35 in ovarian cancer
Investigator(s):Ngan HYS, Chan KKL, Cheung ANY, Leung THY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2011


Project Title:Characterization of tumor initiating cell population expressing CD55 in cervical cancer.
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012


List of Research Outputs

Cai C., Chan D.W. and Ngan H.Y.S., TAK1 overexpression contributes to aggressive ovarian cancer, 18th Hong Kong International Cancer Congress 2011.
Chan D.W. and Ngan H.Y.S., Targeting GRB7/ERK/FOXM1 signaling cascade is a promising therapeutic approach in ovarian cancer, AACR Annual Meeting 2012, Chicago, IL, USA. 2012.
Chan D.W. and Ngan H.Y.S., The potential molecular therapeutic approach in targeting ovarian clear cell carcinoma, Gynecology & Obstetrics. OMICS Group, 2012, 2: 1000e103.
Chan D.W., Liu V.W.S., Leung L.Y., Yao K.M., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells, J Pathol. 2011, 225(4): 525-34.
Chan K.K., Yao T.J., Jones B., Zhao J.F., Ma F.K., Leung C.Y., Lau S.K., Yip M.W. and Ngan H.Y.S., The use of Chinese herbal medicine to improve quality of life in women undergoing chemotherapy for ovarian cancer: a double-blind placebo-controlled randomized trial with immunological monitoring , Ann Oncol. 2011, 22(10): 2241-9.
Chan K.K.L., Kwan T.T.C., Yao T., Tam K.F., Cheung A.N.Y. and Ngan H.Y.S., Human papillomavirus vaccine: What are women most concerned about?, J Obstet Gynaecol Res. 2012, 38(1): 23-30.
Fung K.C.F., Chan D.W., Liu V.W.S., Leung T.H.Y., Cheung A.N.Y. and Ngan H.Y.S., Increased expression of PITX2 transcription factor contributes to ovarian cancer progression, PLos One. PLos, 2012, 7: e37076.
Hui W.Y., Chan D.W. and Ngan H.Y.S., DLX1, a putative downstream target of FOXM1, in regulating ovarian tumorigenesis, The EMBO Meeting 2011 - advancing the life sciences - Vienna. Vienna, Austria, 2011.
Hui W.Y., Chan D.W. and Ngan H.Y.S., Identification of DLX1 as a FOXM1 downstream target in mediating ovarian cancer oncogenesis, 18th Hong Kong International Cancer Congress 2011.
Jiang L., Siu M.K., Wong O.G., Tam K.F., Lu X., Lam E.W., Ngan H.Y.S., Le X.F., Wong E.S., Monteiro L.J., Chan H.Y. and Cheung A.N.Y., iASPP and chemoresistance in ovarian cancers: effects on paclitaxel-mediated mitotic catastrophe, Clinical Cancer Research. 2011, 17(21): 6924-33.
Kondalsamy-Chennakesavan S., Janda M., Gebski V., Baker J., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K.F., Chan K.K.L., Wrede D.H., Pather S., Simcock B., Farrell R., Robertson G., Walker G., McCartney A. and Obermair A., Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial, Eur J Cancer, Apri 12 . 2012.
Kwan T.T.C., Lo S.S., Tam K.F., Chan K.K.L. and Ngan H.Y.S., Assessment of knowledge and stigmatizing attitudes related to human papillomavirus among Hong Kong Chinese healthcare providers, Int J Gynaecol Obstet. 2012, 116(1): 52-6.
Leung T.H.Y., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., Indetification and characterization of cancer stem-like cells in cervical cancer, , Asia-Oceania Research Organization in Genital Infection and Neoplasia (AOGIN) 2012, Hong Kong. 2012.
Leung T.H.Y., Wong S.C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., Significance of p73 in the sensitivity of cancer treatment in gynaecological cancers, Tumor Microenvironment-New Concepts and Molecular Mechanisms, Croucher Advanced Study Institute 2012, Hong Kong. 2012.
Leung T.W., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Methylation at HPV18 E2 binding sites increases during cervical carcinogenesis, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22. 2011.
Li C., Liu V.W.S., Chan D.W., Yao K.M. and Ngan H.Y.S., LY294002 and Metformin Cooperatively Enhance the Inhibition of Growth and the Induction of Apoptosis of Ovarian Cancer Cells., Int J Gynecol Cancer.. 2011, 22: 15-22.
Liu S., Chan Y.K., Leung C.Y., Jiang L., Luk M.H.M., Lo S.T.S., Fong D.Y.T., Cheung A.N.Y., Lin Z.Q. and Ngan H.Y.S., HPV16 and HPV58 integrations in cervical cancer and premalignant lesions, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22. 2011.
Liu X., Chan D.W. and Ngan H.Y.S., Downregulation of miR-199b-5p is associated with chemoresistance via Jagged 1 in human ovarian cancer, 18th Hong Kong International Cancer Congress 2011.
Liu X., Chan D.W. and Ngan H.Y.S., Mechanisms of Chemoresistance in Human Ovarian Cancer at a Glance, Gynecology & Obstetrics. 2012, 2: 1000e104.
Lok T.M., Chan D.W., Liu V.W.S., Hui W.Y., Leung T.H.Y., Yao K.M. and Ngan H.Y.S., Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells, PLoS One. 2011, 6: e23790.
Mak S.L., Chan D.W. and Ngan H.Y.S., Functional characterization of Has-miR-141, a putative oncogene in promoting anchorage-independent growth ability of ovarian cancer cells, 18th Hong Kong International Cancer Congress 2011.
Mak S.L., Chan D.W. and Ngan H.Y.S., miR-141 confers anoikis resistance of ovarian cancer cells by targeting KLF12, AACR Annual Meeting 2012, Chicago, IL, USA. 2012.
Ngan H.Y.S., "The role of tumour markers in gynaecological cancer” & "Role of lymphadenectomy in endometrial cancer" & "Vaccination programmes", 6-8 June, 10th Internatinal Scientific Congress, RCOG, Kuching, Malaysia. 2012.
Ngan H.Y.S., A review of the management of GTN in Hong Kong, The XVIth World Congress on GTD organized by The International Society for the Study of Trophoblastic Diseases and local Hungarian Society in Budapest, October 16-19. 2011.
Ngan H.Y.S., A review of the management of GTN in Hong Kong, The XVIth World Congress on GTD organized by The International Society for the Study of Trophoblastic Diseases and local Hungarian Society in Budapest, October 16-19. 2011.
Ngan H.Y.S., Association between DeltaNp73 expression and HPV Infection in cervical cancer, The 27th International Papillomavirus Conference and Clinical Workshop,, Berlin Germany, 17-22 September. 2011.
Ngan H.Y.S., Liu S., Leung C.Y. and Cheung A.N.Y., Association between DeltaNp73 expression and HPV infection in cervical cancer, 27th International Papillomavirus Conference, Berlin, Germany, Sept.16-22, . 2011.
Ngan H.Y.S., Editorial Board Member - Journal of Clinical Oncology (Chinese Edition) since 2000. 2012.
Ngan H.Y.S., Editorial Board Member - Journal of Medical Association of Thailand. 2012.
Ngan H.Y.S., Editorial Board Member - Journal of Obstetrics and Gynaecology Research since 1997. 2012.
Ngan H.Y.S., Editorial Board Member - Journal of Paediatrics, Gynaecology and Obstetrics since 1997. 2012.
Ngan H.Y.S., Editorial Board Member - The Hong Kong Medical Journal. 2012.
Ngan H.Y.S., Editorial Board Member of 实用婦產科雜誌(編委). 2012.
Ngan H.Y.S., Editorial Member - 中華婦產科雜誌. 2012.
Ngan H.Y.S., Editorial Member - 國際婦產科學雜誌第七屆編輯委員會. 2012.
Ngan H.Y.S., Fertility sparing operations in gynaecological oncology, HKCOG Postgraduate Seminar, Hong Kong, 18 March. 2012.
Ngan H.Y.S., Journal of Gynecologic Oncology (JGO). 2012.
Ngan H.Y.S., Minimally invasive surgery in cervical cancer , The XXII Asian and Oceanic Congress of Obstetrics and Gynaecology (AOCOG) 2011, Taipei, Taiwan, 23-27 September. 2011.
Ngan H.Y.S., Preface. Uterine sarcoma, Best Pract Res Clin Obstet Gynaecol, 2011 Dec; doi: 10.1016/j.bpobgyn.2011.05.012. 2011, 25(6): 679.
Ngan H.Y.S., Robotic Surgery in Gynecology, The "FRESH" International Workshop organized by Ranathibodi Hospital, Bangkok, Thailand, December 1. 2011.
Ngan H.Y.S., Robotic assisted laparoscopic surgery in gynecologic cancers, Macau Regional Meeting of the Asia-Pacific Association for Gynecologic Endoscopy and Minimally Invasive Therapy (APAGE) 2011, 3-4 September. 2011.
Ngan H.Y.S., Robotic assisted laparoscopy surgery in gynaecological oncology, The 12th National Gynaecological Cancer Congress organized by The China Gynaecology Oncology Group of the Chinese Academy of Medicine and local Sichuan societies, Chengdu, October 28-30. 2011.
Ngan H.Y.S., Screening or vaccination - how to combat cervical cancer, AOGIN-India National Conference and pre-conference workshop, Mubai, India, November 4-6. 2011.
Ngan H.Y.S., Staging and Prognostication of Gynaecological , MalignanciesThe First Symposium on Cancer Staging and Prognostication in China, Hong Kong, 10 September. 2011.
Obermair A., Janda M., Baker J., Kondalsamy-Chennakesavan S., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K.F., Chan K.K.L., Wrede D.H., Pather S., Simcock B., Farrell R., Robertson G., Walker G., McCartney A. and Gebski V., Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: results from a randomised controlled trial, Eur J Cancer, 2012 May. 2012, 48(8): 1147-53.
Tse K.Y. and Ngan H.Y.S., Gestational trophoblastic disease, Best Practice & Research Clinical Obstetrics and Gynaecology, 26(2012); 357-370, 27 Jan. 2012.
Tse K.Y., Crawford R. and Ngan H.Y.S., Staging of uterine sarcomas , Best Pract Res Clin Obstet Gynaecol, Jul 12. 2011.
Wei N., Liu S., Chan K.K.L. and Ngan H.Y.S., Tumour Suppressive Function and Modulation of Programmed Cell Death 4 (PDCD4) in Ovarian Cancer, PLoS One. 2012.
Wong G.W., Lo C.K., Chow J.N., Tsun O.K.L., Szeto E., Liu S.S., Ngan H.Y.S. and Cheung A.N.Y., Comparison of GenoFlow HPV test and Linear Array in an Asian Screening Population, In: Wong OG, Lo CK, Chow JN, Tsun OK, Szeto E, Liu SS, Ngan HY, Cheung AN, J Clin Microbiol. 2012.
Wong G.W., Lo C.K., Chow N.K., Tsun O.K.L., Szeto E., Liu S., Ngan H.Y.S. and Cheung A.N.Y., Comparison of the GenoFlow human papillomavirus (HPV) test and the Linear Array assay for HPV screening in an Asian population., J Clin Microbiol.. 2012, 50(5): 1691-7.
Wong G.W., Lo C.K., Chow J.N., Tsun O.K.L., Szeto E., Liu S.S., Ngan H.Y.S. and Cheung A.N.Y., Comparison of the GenoFlow human papillomavirus (HPV) test and the Linear Array assay for HPV screening in an Asian population, In: Wong OG, Lo CK, Chow JN, Tsun OK, Szeto E, Liu SS, Ngan HY, Cheung AN, J Clin Microbiol. 2012.
Zhao F., Siu M.K., Jiang L., Tam K.F., Ngan H.Y.S., Le X.F., Wong G.W., Wong E.S.Y., Chan H.Y. and Cheung A.N.Y., Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival. Histopathology, In: Zhao F, Siu MK, Jiang L, Tam KF, Ngan HY, Le XF, Wong OG, Wong ES, Chan HY, Cheung AN, Histopathology. 2011.


Researcher : Ngu SF

Project Title:A Prospective Randomized Control Study on Vaginoscopic Hysteroscopy and H Pipelle versus Traditional Hysteroscopy and Standard Pipelle
Investigator(s):Ngu SF, Cheung VYT, Pun TC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2011
Completion Date:04/2012


Project Title:10th RCOG International Scientific Congress A Prospective Randomized Study on Vaginoscopy and H Pipelle versus Traditional Hysteroscopy and Standard Pipelle”
Investigator(s):Ngu SF
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2012
Completion Date:06/2012


List of Research Outputs

Ko K.Y.J., Wan H.L., Ngu S.F., Cheung V.Y.T. and Ng E.H.Y., Cesarean scar molar pregnancy, Obstet Gynecol. 2012, 119(2 Pt 2): 449-51.
Ngai F.W. and Ngu S.F., Psychometric Properties of a Chinese Version of the Medical Outcomes Study Family and Marital Functioning Measures in Hong Kong Chinese Childbearing Families, Community Ment Health J. 2011.
Ngai F.W. and Ngu S.F., Translation and validation of a chinese version of the family sense of coherence scale in chinese childbearing families, Nursing Research. 2011, 60: 295-301.
Ngu S.F., Cheung V.Y.T. and Pun T.C., A Prospective Randomized Study on Vaginoscopic Hysteroscopy versus Traditional Hysteroscopy, Postgraduate Study Day, Department of Obstetrics and Gynaecology, Queen Mary Hospital. 2011.
Ngu S.F., Cheung V.Y.T. and Pun T.C., A Prospective Randomized Study on Vaginoscopy and H Pipelle versus Traditional Hysteroscopy and Standard Pipelle, 10th RCOG International Scientific Congress, Kuching, Malaysia. 2012.
Ngu S.F. and Cheung V.Y.T., An update on the management of acute pelvic inflammatory disease, The Hong Kong Medical Diary. 2011, 16: 9-11.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Left upper quadrant approach in gynecologic laparoscopic surgery, In: 2011 Dec;90(12):1406-9., Acta Obstet Gynecol Scand. 2011, 90(12): 1406-9.
Ngu S.F. and Cheung V.Y.T., Non-tubal ectopic pregnancy, Int J Gynaecol Obstet. 2011, 115(3): 295-7.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Randomized Study of Vaginoscopy and H Pipelle vs Traditional Hysteroscopy and Standard Pipelle, J Minim Invasive Gynecol. 2012, 19(2): 206-11.
Ngu S.F., Role of Obstetrician in Achieving Baby Friendly Hospital, Baby Friendly Hospital Initiative: A Journey to Share, Queen Mary Hospital. 2011.
Ngu S.F. and Cheung V.Y.T., Vulvar endometriosis, J Obstet Gynaecol Can. 2011, 33: 891.


Researcher : Ong CYT

Project Title:To determine the correlation of changes in maternal levels of pregnancy-associated plasma protein A (PAPP-A) and free [beta] human chorionic gonadotrophin (F[beta]-hCG) with placental development and fetal outcomes
Investigator(s):Ong CYT, Lao TTH, Leung WC, Leung KY, Lam HSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:First trimester prediction of fetal α-thalassaemia-1 with maternal serum markers, nuchal translucency measurement and three dimentional ultrasound measurement of placental volume
Investigator(s):Ong CYT, Chen M, Leung KY, Tang MHY, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Maternal serum level of ADAM 12 as an early marker of trisomy 21, trisomy 13 and trisomy 18
Investigator(s):Ong CYT, Lee CP, Lau ETK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2007


List of Research Outputs

Johnstone-Ayliffe C., Prior T., Ong C.Y.T., Regan F. and Kumar S., Early procedure-related complications of fetal blood sampling and intrauterine transfusion for fetal anemia, Acta Obstetricia et Gynecologica Scandinavica. 2012, 91: 458-462.


Researcher : Pang RTK

Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang RTK, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007


List of Research Outputs

Cheong A.W.Y., Liu W.M., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., MiR-let-7a regulates integrin-b3 expression and modulates mouse blastocyst attachment in vitro. P.02. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Cheong A.W.Y., Liu W.M., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Role of MicroRNA Let-7 in the implantation of mouse blastocyst. P.1.02, The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.
Kodithuwakkul S.P., Pang R.T.K., Ng E.H.Y., Cheung A.N.Y., Horne A.W., Ho P.C., Yeung W.S.B. and Lee C.K.F., Wnt activation downregulates Olfactomedin-1 (Olfm-1) in Fallopian tubal epithelial cells: an microenvironment predisposed to tubal ectopic pregnancy, Laboratory Investigation . 2012, 92: 256-264.
Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Leung O.N., Pang R.T.K., Ye T., Cheung A.N.Y. and Yeung W.S.B., MiR-135a involves in the formation of tumor-initiating cells in cervical cancer. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.
Liu W., Pang R.T.K., Cheong A.W.Y., Lee C.K.F. and Yeung W.S.B., Excellent Poster Presentation: Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, 2nd SKLRB Symposia on “Frontiers in Reproductive Biology. 2012.
Liu W., Pang R.T.K., Cheong A.W.Y., Ng E.H.Y., Lao K., Lee C.K.F. and Yeung W.S.B., Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, PLoS One. 2012, 7(5): 1-12.
Liu W., Pang R.T.K., Chiu C.N., Wong B.P.C., Lao K., Lee C.K.F. and Yeung W.S.B., Sperm-borne microRNA-34c is required for the first cleavage division in mouse, PNAS. 2012, 109: 490-4.
Pang R.T.K., Lam K.W., Lee C.L., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclase activation elevates MiR-34A and suppresses invasion in the trophoblast cell line BeWo., World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Pang R.T.K., Lam K.W., Lee C.K.F., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclise activation elevates miR-34a and suppresses invasion in the trophoblast cell line BeWo, The 2nd world congress on reproductive biology, 9-12 October 2011, Cairns, Australia. 2011.
Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., miR-135A regulates preimplantation embryo development through down-regulation of E3 Ubiquitin Ligase Seven In Absentia Homolog 1A (SIAH1A) expression. , In: Pang RT, Liu WM, Leung CO, Ye TM, Kwan PC, Lee KF, Yeung WS. , Plos one. 2011, 6: e27878.
Ye T., Pang R.T.K., Leung O.N., Kwan C.K. and Yeung W.S.B., Comparison of early embryo attachment under atmospheric condition and oxygen tension on a three-dimensional endometrium-blastocyst implantation model, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.


Researcher : Pun TC

List of Research Outputs

Chai J., Hon E., Li I.C.F., Pun T.C., Yeung W.S.B. and Ho P.C., A pilot study of pre-operative misoprostol in reducing operative blood loss during hysterectomy, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2011, 158(1): 72-5.
Ngu S.F., Cheung V.Y.T. and Pun T.C., A Prospective Randomized Study on Vaginoscopic Hysteroscopy versus Traditional Hysteroscopy, Postgraduate Study Day, Department of Obstetrics and Gynaecology, Queen Mary Hospital. 2011.
Ngu S.F., Cheung V.Y.T. and Pun T.C., A Prospective Randomized Study on Vaginoscopy and H Pipelle versus Traditional Hysteroscopy and Standard Pipelle, 10th RCOG International Scientific Congress, Kuching, Malaysia. 2012.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Left upper quadrant approach in gynecologic laparoscopic surgery, In: 2011 Dec;90(12):1406-9., Acta Obstet Gynecol Scand. 2011, 90(12): 1406-9.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Randomized Study of Vaginoscopy and H Pipelle vs Traditional Hysteroscopy and Standard Pipelle, J Minim Invasive Gynecol. 2012, 19(2): 206-11.


Researcher : So KH

List of Research Outputs

Gao J., Zuo Y., So K.H., Yeung W.S.B., Ng E.H.Y. and Lee C.K.F., Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. , Spermatogenesis . 2012, 2(1): 53-62.
So K.H., Lee C.L., Yeung W.S.B. and Lee C.K.F., Glycodelin suppresses endometrial cell migration and invasion but stimulates spheroid attachment. , Reprod Biomed Online . 2012, 24(6): 639-45.


Researcher : Tam KF

List of Research Outputs

Chan K.K.L., Kwan T.T.C., Yao T., Tam K.F., Cheung A.N.Y. and Ngan H.Y.S., Human papillomavirus vaccine: What are women most concerned about?, J Obstet Gynaecol Res. 2012, 38(1): 23-30.
Jiang L., Siu M.K., Wong O.G., Tam K.F., Lu X., Lam E.W., Ngan H.Y.S., Le X.F., Wong E.S., Monteiro L.J., Chan H.Y. and Cheung A.N.Y., iASPP and chemoresistance in ovarian cancers: effects on paclitaxel-mediated mitotic catastrophe, Clinical Cancer Research. 2011, 17(21): 6924-33.
Kondalsamy-Chennakesavan S., Janda M., Gebski V., Baker J., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K.F., Chan K.K.L., Wrede D.H., Pather S., Simcock B., Farrell R., Robertson G., Walker G., McCartney A. and Obermair A., Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial, Eur J Cancer, Apri 12 . 2012.
Kwan T.T.C., Lo S.S., Tam K.F., Chan K.K.L. and Ngan H.Y.S., Assessment of knowledge and stigmatizing attitudes related to human papillomavirus among Hong Kong Chinese healthcare providers, Int J Gynaecol Obstet. 2012, 116(1): 52-6.
Obermair A., Janda M., Baker J., Kondalsamy-Chennakesavan S., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K.F., Chan K.K.L., Wrede D.H., Pather S., Simcock B., Farrell R., Robertson G., Walker G., McCartney A. and Gebski V., Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: results from a randomised controlled trial, Eur J Cancer, 2012 May. 2012, 48(8): 1147-53.


Researcher : Tang FOS

Project Title:A prospective randomized comparison of sublingual and vaginal misoprostol in termination of pregnancy in the second trimester
Investigator(s):Tang FOS, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:10/2000


List of Research Outputs

Lee V.C.Y., Tang F.O.S., Ng E.H.Y., Yeung W.S.B. and Ho P.C., A prospective double-blinded, randomized, placebo-controlled trial on the use of letrozole pretreatment with misoprostol for second-trimester medical abortion, Contraception 2011. 2011, 84(6): 628-33.


Researcher : Tang GWK

Project Title:A cross sectional health care study of Chinese perimenopausal women in Hong Kong
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:01/1993


Project Title:Fracture incidence reduction and safety of TSE-424 (Bazedoxifene Acetate) compared to placebo and Raloxifene in osteoporotic postmenopausal women / Endomentrial Safety Substudy
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Wyeth Austral PTY Ltd - General Award
Start Date:02/2002


Project Title:Main Study (013-01)- A study to Evaluate the Efficacy of Quadrivalent HPV (Types 6,11,16 and 18) L1 Virus-Like Particle (VLP) Vaccine in Reducing the Incidence of HPV 6/11-, 16- and 18- Related CIN, and HPV 16 and 18-Related AIS and Cervical Cancer, and HPV 6/11-, 16-, and 18-Related External Genital Warts, VIN and VaIN, and HPV 16 and 18-Related Vulvar and Vaginal Cancer in 16- to 23- Year-Old Women -- The F.U.T.U.R.E. I Study (Females United to Unilaterally Reduce Endo/Ectocervical disease). Substudy (012-01)- Immunogenicity and Safety of Quadrivalent HPV (Types 6,11,16,18)L1 Virus-Like Particle (VLP) Vaccine in 16- to 23-Year-Old Women With an Immunogenicity Bridge Between the HPV 16 Component of the Qualdrivalent Vaccine and the Monovalent HPV 16 Vaccine Pilot Manufacturing Material - The F.U.T.U.R.E. I Study (Females United to Unilaterally Reduce Endo/Ectocervical Disease)
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Merck, Sharp and Dohme (Asia) Ltd. - General Award
Start Date:08/2002


Project Title:A double-blind randomized placebo-controlled clinical trial on the effects of Chinese medicine formula (Erxian Decoction) on menopausal symptoms
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Liu Hao Tsing Education Foundation Limited & Private Outside Practice Fund
Start Date:04/2009


List of Research Outputs

Tang G.W.K., College of O&G Teaching Conference 2011 - Climacteric symptoms as markers for Cardiovascular disease risk during menopause - Herbal Therapies for Menopausal Symptom control, College of Obstetricians & Gynaecologists, Academy of Medicine of Malaysia, December 9-11, 2011, Kuala Lumpur, Malaysia. 2011.
Tang G.W.K., Innovative model of CME/CPD - is it necessary?, 2nd China Continuous Medical Education Conference. March 23-23, 2012. Beijing . 2012.
Zhong L., Tong Y., Tang G.W.K., Choi W.K. and Sze C.W., A Randomized Placebo-controlled trial on the effectiveness of a Chinese herbal formula to alleviate menopausal symptoms, The 10th Meeting of Consortium for Globalization of Chinese Medicine. 2011, 168.


Researcher : Tang MHY

List of Research Outputs

Au P.K., Kwok Y.K., Leung K.Y., Tang L.Y., Tang M.H.Y. and Lau E.T.K., Detection of the S252W mutation in fibroblast growth factor receptor 2 (FGFR2) in fetal DNA from maternal plasma in a pregnancy affected by Apert syndrome, Prenatal Diagnosis. 2011, 31: 218-220.
Chen E.Z., Chiu R.W., Sun H., Akolekar R., Chan K.C., Leung T.Y., Jiang P., Zheng Y.W., Lun F.M., Chan L.Y., Jin Y., Go A.T., Lau E.T.K., To W.W.K., Leung W.C., Tang R.Y., Au-Yeung S.K., Lam H., Kung Y.Y., Zhang X., van Vugt J.M., Minekawa R., Tang M.H.Y., Wang J., Oudejans C.B., Lau T.K., Nicolaides K.H. and Lo Y.M., Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing, PLoS One. 2011, 6: e21791.
Chung B.H.Y., Cheuk D.K.L., Tang M.H.Y., Lau E.T.K., Chan Y.K. and Lau Y.L., Disclosing Results of Autism Genomic Testing-Systematic Review and Applying Its Results to Clinical Practice, International Meeting for Autism Research (IMFAR), Toronto, Ontario, Canada, 17-19 May 2012. 29.
Ho A., Liu A.P.Y., Lun K.S., Tam T., Chan K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., 17p13.3 Class I Microduplication in a Newborn with Microcephaly, Aortic Stenosis and Dysmorphic Facial Features, Hong Kong Journal of Paediatrics (new series). Proceedings of Congress of Joint Annual Scientific Meeting 2011, The Hong Kong Paediatric Society and American Academy Pediatrics in conjunction with Hong Kong Paediatric Nurses Association, 4-5 June 2011. 2011, 16(3): 216.
Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.
Liu A.P.Y., Ng Y.K., Hui P.W., Lau E.T.K., Tang M.H.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2011, 16: 188.
Liu A.P.Y., Ho A., Yung T.C., Tam T., Chan K., Lau E.T.K., Tang M.H.Y., Tan T.Y. and Chung B.H.Y., Inverted Duplication 18q12.1-q22, Hong Kong Journal of Paediatrics (new series). Proceedings of Congress of Joint Annual Scientific Meeting 2011, The Hong Kong Paediatric Society and American Academy Pediatrics in conjunction with Hong Kong Paediatric Nurses Association, 4-5 June 2011. 215, 2011, 16(3).
So J.C.C., Tang M.H.Y., Li C.H., Ha S.Y., Pissard S. and Chan L.C., The First Reported Case of Prenatal Diagnosis for Pyruvate Kinase Deficiency in a Chinese Family , Hematology. 2011, 16(6): 377-379.
Yuan Y., Leung K.Y., Ouyang Y.S., Yang F., Tang M.H.Y., Chau A.K. and Dai Q., Simultaneous real-time imaging of four-chamber and left ventricular outflow tract views using xPlane imaging capability of a matrix array probe, Ultrasound Obstetrics and Gynecology. 2011, 37: 302-309.


Researcher : Tang WF

List of Research Outputs

Lau E.T.K., Tang W.F., Chan S.Y., Ding C.K., Kan A.S.Y., Lee C.P., Hui P.W., Leung K.Y., Ma T., Leung W.C. and Tang M.H.Y., Array CGH Evaluation for Prenatal Diagnosis in Hong Kong, The 16th Conference for Prenatal Diagnosis and Therapy, June 2-6 2012, Miami, USA. 2012.


Researcher : To WWK

List of Research Outputs

Chen E.Z., Chiu R.W., Sun H., Akolekar R., Chan K.C., Leung T.Y., Jiang P., Zheng Y.W., Lun F.M., Chan L.Y., Jin Y., Go A.T., Lau E.T.K., To W.W.K., Leung W.C., Tang R.Y., Au-Yeung S.K., Lam H., Kung Y.Y., Zhang X., van Vugt J.M., Minekawa R., Tang M.H.Y., Wang J., Oudejans C.B., Lau T.K., Nicolaides K.H. and Lo Y.M., Noninvasive prenatal diagnosis of fetal trisomy 18 and trisomy 13 by maternal plasma DNA sequencing, PLoS One. 2011, 6: e21791.
Chiu R.W., Akolekar R., Zheng Y.W., Leung T.Y., Sun H., Chan K.C., Lun F.M., Go A.T., Lau E.T.K., To W.W.K., Leung W.C., Tang R.Y., Au-Yeung S.K., Lam H., Kung Y.Y., Zhang X., ean Vugt J.M., Minekawa R., Tang M.H., Wang J., Oudejans C.B., Lau T.K., Nicolaides K.H. and Lo Y.M., Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study, British Medical Journal. 2011, 342: c7401.


Researcher : Tsang H

List of Research Outputs

Cheung T.Y., Tsang H., Wong C.K., Yeung W.S.B. and Lee C.K.F., The endocrine disruptive chemical bispenol modulates Wnt-signaling for spheroid attachment onto endometrial cells. P.03. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction, Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Tsang H., Cheung T.Y., Kodithuwakku K.S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. , Reprod Toxicol . 2012, 33: 60-66.


Researcher : Tsang H

List of Research Outputs

Cheung T.Y., Tsang H., Wong C.K., Yeung W.S.B. and Lee C.K.F., The endocrine disruptive chemical bispenol modulates Wnt-signaling for spheroid attachment onto endometrial cells. P.03. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction, Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Tsang H., Cheung T.Y., Kodithuwakku K.S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. , Reprod Toxicol . 2012, 33: 60-66.


Researcher : Tse KY

List of Research Outputs

Tse K.Y. and Ngan H.Y.S., Gestational trophoblastic disease, Best Practice & Research Clinical Obstetrics and Gynaecology, 26(2012); 357-370, 27 Jan. 2012.
Tse K.Y., Crawford R. and Ngan H.Y.S., Staging of uterine sarcomas , Best Pract Res Clin Obstet Gynaecol, Jul 12. 2011.


Researcher : Wan HL

List of Research Outputs

Ko K.Y.J., Wan H.L., Ngu S.F., Cheung V.Y.T. and Ng E.H.Y., Cesarean scar molar pregnancy, Obstet Gynecol. 2012, 119(2 Pt 2): 449-51.


Researcher : Wong BPC

List of Research Outputs

Liu W., Pang R.T.K., Chiu C.N., Wong B.P.C., Lao K., Lee C.K.F. and Yeung W.S.B., Sperm-borne microRNA-34c is required for the first cleavage division in mouse, PNAS. 2012, 109: 490-4.


Researcher : Wong ST

List of Research Outputs

Wong S.T., Yeung W.S.B. and Chiu C.N., Adrenomedullin stimulates human trophoblast invasion through the upregulation of nitric oxide and urokinase plasminogen activator activity., In: Society for the Study of Reproduction, 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A., JUL 31-AUG 4.. U.S.A., 2011.


Researcher : Xiang L

List of Research Outputs

Xiang L., Chan R.W.S. and Yeung W.S.B., Development of a fluorescent cell tracking technique for isolation of human endometrial stromal stem/progenitor cells, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 6 November 2011, Hong Kong.. 2011.
Xiang L., Chan R.W.S. and Yeung W.S.B., Identification of putative human endometrial stem cells using fluorescent cell tracking. O.2.23., The 16th Research Postgraduate Symposium, HKU. December 7-8, 2011, Hong Kong. 2011.


Researcher : Xin M

List of Research Outputs

Xin M., Lee C.Y.L., Yeung W.S.B. and Ho P.C., The Expression and Role of Adamts9 during Human Embryonic Stem Cell Differentiation, 1st annual Cambridge Stem Cell international symposium . 2011.


Researcher : Ye T

List of Research Outputs

Leung O.N., Pang R.T.K., Ye T., Cheung A.N.Y. and Yeung W.S.B., MiR-135a involves in the formation of tumor-initiating cells in cervical cancer. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.
Ye T., Pang R.T.K., Leung O.N., Kwan C.K. and Yeung W.S.B., Comparison of early embryo attachment under atmospheric condition and oxygen tension on a three-dimensional endometrium-blastocyst implantation model, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.


Researcher : Yeung TWY

List of Research Outputs

Yeung T.W.Y., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., HKCOG guidelines: induction of ovulation, Journal of Paediatrics, Obstetrics and Gynaecology. 2012, Jan/Feb: 5-31.


Researcher : Yeung WSB

Project Title:Characterization of Stem/Progenitor Cells in Human Endometriosis
Investigator(s):Yeung WSB, Chan RWS, Lee CKF, Luk JMC, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


Project Title:Role of microRNA let-7 in implantation of mouse blastocysts
Investigator(s):Yeung WSB, Lee CKF, Liu W, Pang RTK
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2011


Project Title:Control of human extravillous cytotrophoblast invasion by adrenomedullin
Investigator(s):Yeung WSB, Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2011
Completion Date:02/2013


Project Title:World Congress on Reproductive Biology 2011 Glycodelin-C and the role of cumulus complex in natural sperm quality selection
Investigator(s):Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2011
Completion Date:10/2011


Project Title:MicroRNA-135a induction transforms normal human papillomarvirus infected cervical cells into cells with cancer stem cell-like properties.
Investigator(s):Yeung WSB, Pang RTK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


List of Research Outputs

Cao M., Chan R.W.S. and Yeung W.S.B., Identification of endometrial label retaining cells in postpartum mice, Days of Molecular Medicine 2012. 10-12 November 2011, Hong Kong . 2011.
Cao S., Yeung W.S.B. and Lee C.K.F., Functional Study of an Acrosome-Expressing Gene, VAD1.2 in Mice Spermatogenesis. P.583, The 44th Annual Meeting. Society for the Study of Reproduction. July 31 – Aug 4, 2011, Portland, Oregon . 2011.
Cao S.B., Yeung W.S.B. and Lee C.K.F., Functional study of VAD1.2 deficiency on spermatogenesis in mice. O.2.01., The 16th Research Postgraduate Symposium, HKU. December 7-8, 2011, Hong Kong.. 2011.
Chai J., Hon E., Li I.C.F., Pun T.C., Yeung W.S.B. and Ho P.C., A pilot study of pre-operative misoprostol in reducing operative blood loss during hysterectomy, European Journal of Obstetrics and Gynecology and Reproductive Biology. 2011, 158(1): 72-5.
Chai J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Ovarian stimulation modulates steroid receptor expression and spheroid attachment in peri-implantation endometria: studies on natural and stimulated cycles, Fertility Sterility. 2011, 96(3): 764-768.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophage promoted the colony forming ability of putative endometrial stromal stem cells, Days of Molecular Medicine 2012, 10-12 November 2011, Hong Kong. 2011.
Chan R.W.S., Chan Y.Y., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Macrophages Increased the Colony Forming Activity of Putative Endometrial and Endometriotic Stromal Stem Cells, World Congress for Endometriosis. 2011.
Chen C.H., Lee Y.L., Lee C.K.F. and Yeung W.S.B., Role of MicroRNAs in reprogramming of somatic cells into induced pluripotent stem cells. P.1.01, The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong. 2011.
Chen C.H., Lee Y.L., Lee C.K.F. and Yeung W.S.B., Role of microRNAs in reprogramming of somatic cells into induced pluripotent stem cells. P.01., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Cheong A.W.Y., Liu W.M., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., MiR-let-7a regulates integrin-b3 expression and modulates mouse blastocyst attachment in vitro. P.02. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Cheong A.W.Y., Liu W.M., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Role of MicroRNA Let-7 in the implantation of mouse blastocyst. P.1.02, The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.
Cheung T.Y., Tsang H., Wong C.K., Yeung W.S.B. and Lee C.K.F., The endocrine disruptive chemical bispenol modulates Wnt-signaling for spheroid attachment onto endometrial cells. P.03. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction, Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Chiu C.N., Lam K.K., Lee C.L., Huang V.W., Wong B.S., Zhao W., Li K., Ho P.C. and Yeung W.S.B., Adrenomedullin enhances the progressive motility and zona pellucida-binding capacity of spermatozoa from normozoospermic but not asthenozoospermic men, Molecular Reproduction and Development. 2012, 79(2): 76.
Gao J., Zuo Y., So K.H., Yeung W.S.B., Ng E.H.Y. and Lee C.K.F., Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. , Spermatogenesis . 2012, 2(1): 53-62.
Gao J., Zuo Y., Yeung W.S.B. and Lee C.K.F., Potential role of VAD1.3 in spermatogenesis and fertilization. O.2.05. , The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.
Huang W., Chiu C.N., Yeung W.S.B. and Ho P.C., Sperm fucosyltransferase-5 interacts with oviductal cell membrane proteins to protect human spermatozoa from oxidative stress., In: Society for the Study of Reproduction, 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A., JUL 31-AUG 4.. U.S.A., 2011.
Kodithuwakkul S.P., Pang R.T.K., Ng E.H.Y., Cheung A.N.Y., Horne A.W., Ho P.C., Yeung W.S.B. and Lee C.K.F., Wnt activation downregulates Olfactomedin-1 (Olfm-1) in Fallopian tubal epithelial cells: an microenvironment predisposed to tubal ectopic pregnancy, Laboratory Investigation . 2012, 92: 256-264.
Lam K.K., Lee C.L., Lee C.K.F., Ho P.C., Yeung W.S.B. and Chiu C.N., Glycodelin-A interacts with siglec-6 to suppress trophoblast invasion. P.08., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 Nov 2011, Hong Kong.. 2011.
Lam K.W., Chiu C.N., Lee C.L., Pang R.T.K., Leung O.N., Koistinen H., Seppala M., Ho P.C. and Yeung W.S.B., Glycodelin-A protein interacts with Siglec-6 protein to suppress trophoblast invasiveness by down-regulating extracellular signal-regulated kinase (ERK)/c-Jun signaling pathway., The Journal of Biological Chemistry. 2011, 286: 37118-27.
Lam P.Y., Siu S.O., Ng C.M.D., Kong P.W., Yeung W.S.B., Lo C.S.C. and Chu I.K., Online combination of reverse-phase-reverse-phase and porous graphitic carbon liquid chromatography for multi-component separation of proteomics and glycoproteomics samples, Electrophoresis. 2011, 1-11.
Lam P.Y., Lau E., Siu S.O., Ng C.M.D., Kong P.W., Chiu C.N., Yeung W.S.B., Lo C.S.C. and Chu I.K., Online combination of reversed-phase/reversed-phase and porous graphitic carbon liquid chromatography for multicomponent separation of proteomics and glycoproteomics samples., Electrophoresis. 2011, 32: 2930-40.
Lam Y.F.E., Lee C.L., Yeung W.S.B. and Chiu C.N., The immunomodulatory properties of glycodelin-A on human monocyte and macrophage., In: Society for the Study of Reproduction., 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A, JUL 31-AUG 4.. U.S.A, 2011.
Lee C.L., Chiu C.N., Pang P.C., Chu I.K., Lee C.K.F., Koistinen R., Koistinen H., Seppala M., Morris H.R., Tissot B., Panico M., Dell A. and Yeung W.S.B., HKU Strategic Research Areas & Themes “Reproduction and Development” Best Research Output Award 2011 (2nd Prize): Glycosylation failure extends to glycoproteins in gestational diabetes: Evidence from reduced alpha 2-6 sialylation and impaired immunomodulatory activities of pregnancy-related glycodelin-A. Diabetes. 2011;60(3):909-17., HKU Strategic Research Areas & Themes “Reproduction and Development”. 2011.
Lee V.C., Chan C.C.W., Ng E.H.Y., Yeung W.S.B. and Ho P.C., Sequential use of letrozole and gonadotrophin in women with poor ovarian reserve: a randomized controlled trial, Reproductive BioMedicine Online 2011. 2011, 23(3): 380-8.
Lee V.C.Y., Tang F.O.S., Ng E.H.Y., Yeung W.S.B. and Ho P.C., A prospective double-blinded, randomized, placebo-controlled trial on the use of letrozole pretreatment with misoprostol for second-trimester medical abortion, Contraception 2011. 2011, 84(6): 628-33.
Leung O.N., Pang R.T.K., Ye T., Cheung A.N.Y. and Yeung W.S.B., MiR-135a involves in the formation of tumor-initiating cells in cervical cancer. , The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.
Li H.W., Anderson R.A., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Evaluation of serum antimullerian hormone and inhibin B concentrations in the differential diagnosis of secondary oligoamenorrhea, Fertility and Sterility 2011. 2011, 96(3): 774-9.
Li R.H.W., Wong C.Y.G., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Response to letter to the editor: Serum anti-Mullerian hormone level is not altered in women using hormonal contraceptives, Contraception. 2011, 85(5): 520-521.
Liao S., Li R.H.W., Ho J.C.M., Yeung W.S.B., Ng E.H.Y., Cheung A.N.Y., Tang F. and O W.S., Possible role of adrenomedullin in the pathogenesis of tubal ectopic pregnancy, Journal of Clinical Endocrinology and Metabolism . Journal of Clinical Endocrinolog and Metabolism, 2012, 97: 2105-2112.
Liu W., Pang R.T.K., Cheong A.W.Y., Ng E.H.Y., Lao K., Lee C.K.F. and Yeung W.S.B., Involvement of microRNA Lethal-7a in the Regulation of Embryo Implantation in Mice, PLoS One. 2012, 7(5): 1-12.
Liu W., Pang R.T.K., Chiu C.N., Wong B.P.C., Lao K., Lee C.K.F. and Yeung W.S.B., Sperm-borne microRNA-34c is required for the first cleavage division in mouse, PNAS. 2012, 109: 490-4.
O W.S., Liao S., Li R.H.W., Ho J.C.M., Ng E.H.Y., Yeung W.S.B., Cheung A.N.Y. and Tang F., The role of adrenomedullin in tubal ectopic pregnancy, World Congress on Reproductive Biology Abstracts, Cairns, Australia. 2011, 81 Abstract 124.
Pang P.C., Chiu C.N., Lee C.L., Chang L.Y., Panico M., Morris H.R., Haslam S.M., Khoo K.H., Clark G.F., Yeung W.S.B. and Dell A., Faculty of 1000 “Naturally Selected” on December 2011: Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida. Science. 2011;333(6050):1761-4. , Faculty of 1000. 2011.
Pang P.C., Chiu C.N., Lee C.L., Chang L.Y., Panico M., Morris H.R., Haslam S.M., Khoo K.H., Clark G.F., Yeung W.S.B. and Dell A., Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucida., Science. 2011, 333: 1761-4.
Pang R.T.K., Lam K.W., Lee C.L., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclase activation elevates MiR-34A and suppresses invasion in the trophoblast cell line BeWo., World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Pang R.T.K., Lam K.W., Lee C.K.F., Chiu C.N., Leung O.N. and Yeung W.S.B., Adenylate cyclise activation elevates miR-34a and suppresses invasion in the trophoblast cell line BeWo, The 2nd world congress on reproductive biology, 9-12 October 2011, Cairns, Australia. 2011.
Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., miR-135A regulates preimplantation embryo development through down-regulation of E3 Ubiquitin Ligase Seven In Absentia Homolog 1A (SIAH1A) expression. , In: Pang RT, Liu WM, Leung CO, Ye TM, Kwan PC, Lee KF, Yeung WS. , Plos one. 2011, 6: e27878.
So K.H., Lee C.L., Yeung W.S.B. and Lee C.K.F., Glycodelin suppresses endometrial cell migration and invasion but stimulates spheroid attachment. , Reprod Biomed Online . 2012, 24(6): 639-45.
Tsang H., Cheung T.Y., Kodithuwakku K.S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) suppresses spheroids attachment on endometrial epithelial cells through the down-regulation of the Wnt-signaling pathway. , Reprod Toxicol . 2012, 33: 60-66.
Wong S.T., Yeung W.S.B. and Chiu C.N., Adrenomedullin stimulates human trophoblast invasion through the upregulation of nitric oxide and urokinase plasminogen activator activity., In: Society for the Study of Reproduction, 44th Annual Meeting of the Society for the Study of Reproduction. Portland, Oregon, U.S.A., JUL 31-AUG 4.. U.S.A., 2011.
Xiang L., Chan R.W.S. and Yeung W.S.B., Development of a fluorescent cell tracking technique for isolation of human endometrial stromal stem/progenitor cells, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 6 November 2011, Hong Kong.. 2011.
Xiang L., Chan R.W.S. and Yeung W.S.B., Identification of putative human endometrial stem cells using fluorescent cell tracking. O.2.23., The 16th Research Postgraduate Symposium, HKU. December 7-8, 2011, Hong Kong. 2011.
Xin M., Lee C.Y.L., Yeung W.S.B. and Ho P.C., The Expression and Role of Adamts9 during Human Embryonic Stem Cell Differentiation, 1st annual Cambridge Stem Cell international symposium . 2011.
Ye T., Pang R.T.K., Leung O.N., Kwan C.K. and Yeung W.S.B., Comparison of early embryo attachment under atmospheric condition and oxygen tension on a three-dimensional endometrium-blastocyst implantation model, The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 6 November 2011, Hong Kong. 2011.
Yeung W.S.B. and Chiu C.N., Glycodelin-C and the role of cumulus complex in natural sperm quality selection. , World Congress of Reproductive Biology. Cairns, Queensland, Australia, Oct 9-12.. Australia, 2011.
Yeung W.S.B. and Chiu C.N., SLeX: potential implications for fertility and contraception, Expert Review of Obstetrics & Gynecology. 2012, 7: 1-3.


Researcher : Yip MW

List of Research Outputs

Chan K.K., Yao T.J., Jones B., Zhao J.F., Ma F.K., Leung C.Y., Lau S.K., Yip M.W. and Ngan H.Y.S., The use of Chinese herbal medicine to improve quality of life in women undergoing chemotherapy for ovarian cancer: a double-blind placebo-controlled randomized trial with immunological monitoring , Ann Oncol. 2011, 22(10): 2241-9.


Researcher : Yung SF

Project Title:A randomized comparative trial to compare the efficacy of vaginal misoprostol moistened with 5% acetic acid with dry vaginal misoprostol in the medical management of first trimester silent miscarriage
Investigator(s):Yung SF, Ho PC, Ng EHY, Lee VCY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2011


List of Research Outputs

Lee V.C.Y., Yung S.F., Li R.H.W., Watzer B., Schweer H., Ng E.H.Y. and Ho P.C., A randomized comparison of pharmacokinetics of a single vaginal dose of dry misoprostol or misoprostol moistened with normal saline or with acetic acid, Human Reproduction. 2011, 26(11): 2981-7.


Researcher : Zuo Y

List of Research Outputs

Gao J., Zuo Y., So K.H., Yeung W.S.B., Ng E.H.Y. and Lee C.K.F., Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. , Spermatogenesis . 2012, 2(1): 53-62.
Gao J., Zuo Y., Yeung W.S.B. and Lee C.K.F., Potential role of VAD1.3 in spermatogenesis and fertilization. O.2.05. , The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.


Researcher : Zuo Y

List of Research Outputs

Gao J., Zuo Y., So K.H., Yeung W.S.B., Ng E.H.Y. and Lee C.K.F., Electroacupuncture enhances spermatogenesis in rats after scrotal heat treatment. , Spermatogenesis . 2012, 2(1): 53-62.
Gao J., Zuo Y., Yeung W.S.B. and Lee C.K.F., Potential role of VAD1.3 in spermatogenesis and fertilization. O.2.05. , The 16th Research Postgraduate Symposium, HKU. 7 & 8 Dec 2011, Hong Kong.. 2011.


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