LKS MEDICAL FACULTY
| Researcher : Boheler KR |
| List of Research Outputs |
| Chow M.Z.Y., Geng L., Kong M.C.W., Keung W.W.Y., Fung J.C., Boheler K.R. and Li R.A., Epigenetic regulation of the electrophysiological phenotype of human embryonic stem cell (hESC)-derived ventricular cardiomyocytes: Insights into driven maturation and hypertrophic growth., Stem Cells Dev. . 2013. |
| Guan D., Shao J., Zhao Z., WANG P., Qin J., Deng Y., Boheler K.R., Wang J.J. and Yan B., PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data, Nucleic Acids Research. 2014. |
| Keung W.W.Y., Boheler K.R. and Li R.A., Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes, Stem Cell Research & Therapy. 2014, 5: 17. |
| Poon N.Y.E., Yan B., Zhang S., Keung W.W.Y., Ren L., Geng L., Kong M.C.W., WANG J., Boheler K.R. and Li R.A., Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes., PloS One. . 2013. |
| Researcher : Chan YS |
| Project Title: | 30th Annual Conference of Society for Neuroscience Expression of N-Methyl-D-Aspartate Receptor Subunits and Induction of c-fos in Otolith Neurons in the Vestibular Nuclei of Postnatal Rats |
| Investigator(s): | Chan YS |
| Department: | Physiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2000 |
| Project Title: | 31st Annual Meeting of Society for Neuroscience Expression of Neurotrophin Receptors in Vestibular Nuclei During the Postnatal Development of the Rat |
| Investigator(s): | Chan YS |
| Department: | Physiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2001 |
| Project Title: | XXIV Annual Conference of Indian Academy of Neurosciences Development Refinement of Spatial Recognition Circuits |
| Investigator(s): | Chan YS |
| Department: | Physiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 12/2006 |
| Project Title: | Role of the thalamus in integrating spatial information and guiding navigation |
| Investigator(s): | Chan YS |
| Department: | Physiology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2009 |
| Project Title: | Outstanding Research Student Supervisor Award 2009-10 |
| Investigator(s): | Chan YS |
| Department: | Physiology |
| Source(s) of Funding: | Outstanding Research Student Supervisor Award |
| Start Date: | 12/2010 |
| Project Title: | Brain-derived neurotrophic factor regulates plasticity in the vestibular system |
| Investigator(s): | Chan YS, Shum DKY |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2010 |
| Completion Date: | 11/2013 |
| Project Title: | Vestibular nuclear signals regulate the postnatal development of a thalamic network for spatial navigation |
| Investigator(s): | Chan YS, Shum DKY |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2011 |
| Project Title: | Long-term depression of inhibitory responses is critical to the maturation of the vestibular circuitry |
| Investigator(s): | Chan YS, Shum DKY |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2012 |
| Project Title: | IUPS 2013; Plasticity of GABAergic synapses in the developing vestibular nucleus governs the expression of spatial navigation in mature rats |
| Investigator(s): | Chan YS |
| Department: | Physiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2013 |
| Completion Date: | 07/2013 |
| Project Title: | Serotonin-induced bidirectional modulation of activity-dependent synaptic plasticity tunes vestibular functions |
| Investigator(s): | Chan YS, Shum DKY |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2013 |
| List of Research Outputs |
| Gao J., Cheung R.T.F., Chan Y.S., Chu L.W., Mak H.K.F. and Lee T.M.C., The relevance of short-range fibers to cognitive efficiency and brain activation in aging and dementia., PLoS ONE. 2014, 9(4): e90307. |
| Researcher : Chen JHK |
| Project Title: | Molecular epidemiology study of HIV-1 among the men who have sex with men (MSM) population in Hong Kong |
| Investigator(s): | Chen JHK, Yam WC |
| Department: | Microbiology |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 04/2009 |
| List of Research Outputs |
| To S., Chen J.H.K., Wong K., Chan K., Chen Z. and Yam W.C., Determination of the High Prevalence of Dual/Mixed- or X4-Tropism Among HIV Type 1 CRF01_AE in Hong Kong by Genotyping and Phenotyping Methods, AIDS Research and Human Retroviruses. 2013, 29: 1123-1128. |
| Researcher : Chen Z |
| Project Title: | A novel model for the study of lung pathogenesis of SARS |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | National Institutes of Health, US Department of Health and Human Services - General Award |
| Start Date: | 08/2007 |
| Project Title: | Understanding the Ongoing HIV Epidemic in Yunnan China |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | China AIDS Initiative - General Award |
| Start Date: | 05/2008 |
| Project Title: | Preventing HIV-1 infection using a novel vaccine immunogen |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Global Health Grants |
| Start Date: | 10/2008 |
| Project Title: | Establishment of a rapid, high-throughput, cost-effective HIV-1 drug resistance testing system |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 05/2011 |
| Project Title: | A Novel Vaccine for Mesothelioma Immunotherapy and Prevention; |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Pneumoconiosis Compensation Fund Board - General Award |
| Start Date: | 07/2011 |
| Project Title: | A promising mucosal prime and intramuscular boost AIDS vaccine regimen |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2011 |
| Project Title: | AIDS Vaccine 2011 A Novel Vaccine Design for Inducing Robust HIV-1 Specific Immunity |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2011 |
| Project Title: | A Novel Vaccine for Tuberculosis Prevention |
| Investigator(s): | Chen Z, Yam WC |
| Department: | Microbiology |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 11/2011 |
| Project Title: | Blocking HIV infection by gene-encoding neutralizing antibodies |
| Investigator(s): | Chen Z, Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2012 |
| Project Title: | AIDS Vaccine 2012; Mucosal Prime with a Replicating Vaccinia-based Vaccine Promotes Mucosal Immunity against SIV. |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2012 |
| Project Title: | Mechanism of a soluble PD-1-based vaccine in amplifying antiviral CD8+ T-cell immunity |
| Investigator(s): | Chen Z, Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Novel Secretory Immunoadhesins for HIV Prevention |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Project Title: | To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System |
| Investigator(s): | Chen Z, Liu L, Cheung KW, Du DY |
| Department: | Microbiology |
| Source(s) of Funding: | Guangdong-Hong Kong Technology Cooperation Funding Scheme |
| Start Date: | 07/2013 |
| Project Title: | AIDS Vaccine 2013 Conference; Mechanism of a Novel PD1-Based DNA Vaccine in Amplifying HIV-1 GAG-Specific CD8+ T Cells in Mice |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2013 |
| Completion Date: | 10/2013 |
| Project Title: | Further optimization of live viral vector for HIV vaccine research |
| Investigator(s): | Chen Z, Wang H |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 11/2013 |
| Project Title: | To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System |
| Investigator(s): | Chen Z, Liu L, Cheung KW, Du DY |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 12/2013 |
| Project Title: | Mechanism of potentiating HIV antigen-specific CD8+ T cells |
| Investigator(s): | Chen Z, Liu L, Yam WC, Cheung KLA, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2014 |
| List of Research Outputs |
| Liang J., Chen J., Tan Z., Peng J., Zheng X., Nishiura K., Ng J., Wang Z., Wang D., Chen Z. and Liu L., Extracts of medicinal herb Sanguisorba officinalis inhibit the entry of human immunodeficiency virus type one. , JFDA. 2013, 21(4): 52-58. |
| Xiao H., Liu L., Zhu Q., Tan Z., Yu W., Tang X., Zhan D., Du D.Y., Wang H., Liu D., Li Z., Jiang X., Yuen K.Y., Ho D., Gao F. and Chen Z., A Replicating Modified Vaccinia Tiantan Strain Expressing an Avian-Derived Influenza H5N1 Hemagglutinin Induce Broadly Neutralizing Antibodies and Cross-Clade Protective Immunity in Mice, PLoS ONE. 2013, 8: e83274. |
| Researcher : Cheung KLA |
| Project Title: | Transmission of HIV from infected myeloid progenitor cells to T cells |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2012 |
| Completion Date: | 11/2013 |
| Project Title: | Human cytomegalovirus and human immunodeficiency virus type 1 co-infection of CD34+ Myeloid Progenitor Cells |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2013 |
| Project Title: | Transfer of HIV-1 from HIV-1 latently infected CD34+ hematopoietic progenitors to CD4+ T cells |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| List of Research Outputs |
| ZHOU J., Cheung K.L.A., Liu H., TAN Z., TANG X., KANG Y., Du Y., Wang H., Liu L. and Chen Z., Potentiating Functional Antigen-specific CD8+ T Cell Immunity by a Novel PD1 Isoform-based Fusion DNA Vaccine, Molecular Therapy. 2013, 21: 1445-1455. |
| Researcher : Cheung KW |
| Project Title: | Type of cell death and related mechanisms for gut homing CD4 T cells during human immunodeficiency virus-1 (HIV-1) infection |
| Investigator(s): | Cheung KW, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Project Title: | Role of microvesicles released by HIV-1 infected gut homing CD4 T cells in AIDS pathogenesis |
| Investigator(s): | Cheung KW, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Researcher : Du DY |
| List of Research Outputs |
| Xiao H., Liu L., Zhu Q., Tan Z., Yu W., Tang X., Zhan D., Du D.Y., Wang H., Liu D., Li Z., Jiang X., Yuen K.Y., Ho D., Gao F. and Chen Z., A Replicating Modified Vaccinia Tiantan Strain Expressing an Avian-Derived Influenza H5N1 Hemagglutinin Induce Broadly Neutralizing Antibodies and Cross-Clade Protective Immunity in Mice, PLoS ONE. 2013, 8: e83274. |
| Researcher : Du Y |
| List of Research Outputs |
| ZHOU J., Cheung K.L.A., Liu H., TAN Z., TANG X., KANG Y., Du Y., Wang H., Liu L. and Chen Z., Potentiating Functional Antigen-specific CD8+ T Cell Immunity by a Novel PD1 Isoform-based Fusion DNA Vaccine, Molecular Therapy. 2013, 21: 1445-1455. |
| Researcher : Geng L |
| List of Research Outputs |
| Chow M.Z.Y., Geng L., Kong M.C.W., Keung W.W.Y., Fung J.C., Boheler K.R. and Li R.A., Epigenetic regulation of the electrophysiological phenotype of human embryonic stem cell (hESC)-derived ventricular cardiomyocytes: Insights into driven maturation and hypertrophic growth., Stem Cells Dev. . 2013. |
| Poon N.Y.E., Yan B., Zhang S., Keung W.W.Y., Ren L., Geng L., Kong M.C.W., WANG J., Boheler K.R. and Li R.A., Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes., PloS One. . 2013. |
| Researcher : He M |
| Project Title: | Regulation of ion channels by angiotensin II in human cardiac fibroblasts |
| Investigator(s): | He M, Li GR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2009 |
| Researcher : Ho PC |
| List of Research Outputs |
| Chai J. and Ho P.C., Medical abortion after 9 weeks, Abortion Care. 2014. |
| Researcher : Hui EC |
| Project Title: | Promotion of the reflection, dialogue and teaching of ethical issues related to the development and uses of biotechnologies among students and faculty members of health-related sciences at the University of Hong Kong |
| Investigator(s): | Hui EC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Teaching Development Grants |
| Start Date: | 03/2005 |
| Researcher : Kong MCW |
| Project Title: | Characterization of early-staged human embryonic stem cells cardiomyocytes (hESC-CMs): A potential cell source for successful cardiomyoplasty |
| Investigator(s): | Kong MCW, Li RA |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2012 |
| Completion Date: | 04/2014 |
| Project Title: | Generation of homogeneous ventricular cardiomyocytes (VCMs) from human pluripotent stem cells (hPSC) |
| Investigator(s): | Kong MCW |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2012 |
| Completion Date: | 05/2014 |
| List of Research Outputs |
| Chow M.Z.Y., Geng L., Kong M.C.W., Keung W.W.Y., Fung J.C., Boheler K.R. and Li R.A., Epigenetic regulation of the electrophysiological phenotype of human embryonic stem cell (hESC)-derived ventricular cardiomyocytes: Insights into driven maturation and hypertrophic growth., Stem Cells Dev. . 2013. |
| Karakikes I.C., Senyei G.D., Kong M.C.W., Lieu D.K., WANG J., Jackson T., Hulot J.S., Li R.A. and Hajjar R.J., Small Molecule-Mediated Directed Differentiation of Human Embryonic Stem Cells Toward Ventricular Cardiomyocytes. Stem Cell Translational Medicine. , Stem Cells Translational Medicine. 2014, 3: 18-31. |
| Poon N.Y.E., Yan B., Zhang S., Keung W.W.Y., Ren L., Geng L., Kong M.C.W., WANG J., Boheler K.R. and Li R.A., Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes., PloS One. . 2013. |
| Researcher : Lai WWK |
| Project Title: | Open label, prospective, double arm, randomized, pilot study to evaluate the safety and efficacy of the same day administration of PDT with verteporfin and an intravitreal injection of ranibizumab vs. ranibizumab monotherapy for the treatment of subfoveal CNV secondary to neovascular age related macular degeneration in the Asian population |
| Investigator(s): | Lai WKW, Li KKW, Wong DSH, McGhee S, Lam CLK, Chan WSC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Pharmaceutical Industry - General Award |
| Start Date: | 07/2008 |
| Project Title: | Production of Iris Pigment Epithelial Cells for transplantation to treat Age-Related Macular Degeneration |
| Investigator(s): | Lai WKW, Lo ACY, Fletcher C, Wong DSH |
| Department: | Ophthalmology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2009 |
| Project Title: | To introduce ranibizumab (Licentis) for the treatment of diabetic macular edema to Queen Mary Hospital and to access the quality of life and utility values before and after the treatment |
| Investigator(s): | Lai WKW, Wong DSH, Li KKW |
| Department: | Ophthalmology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 07/2010 |
| Researcher : Lam SK |
| Project Title: | Biotech Company in the Faculty of Medicine, The University of Hong Kong |
| Investigator(s): | Lam SK |
| Department: | Medicine |
| Source(s) of Funding: | The University of Hong Kong Foundation Seed Grant |
| Start Date: | 07/2003 |
| Project Title: | Treatment of gastrointestinal cancer by targeting survivin using adeno-associated virus gene delivery system |
| Investigator(s): | Lam SK, Wong BCY, Lin MC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2004 |
| Researcher : Lam TH |
| List of Research Outputs |
| Lam T.H., Lui E., Chau S., Kueh C.S., Yung Y.K. and Yam W.C., Evaluation of real-time PCR for quantitative detection of Escherichia coli in beach water, J Water Health. 2014, 12(1): 51-6. |
| Researcher : Lau WCS |
| Project Title: | Prospective study of the clinical pattern of systemic lupus erythematosus in Hong Kong |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/1993 |
| Project Title: | Effects of sex hormones on lymphocyte function in systemic lupus erythematosus |
| Investigator(s): | Lau WCS, Mok TMY |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2002 |
| Project Title: | A study to evaluate the immunopathology of Severe Acute Respiratory Syndrome |
| Investigator(s): | Lau WCS, Chan YTE, Cheung BMY |
| Department: | Medicine |
| Source(s) of Funding: | VCO SARS Research Fund |
| Start Date: | 07/2003 |
| Project Title: | Evaluation of the effects of sex hormones on neutrophils and macrophage apoptosis and macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Project Title: | Dendritic cell function and their effects on B cell activation in systemic lupus erythematosus |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2005 |
| Project Title: | Interactions between plasmacytoid dendritic cells and T regulatory / interleukin-17 producing T-helper cells in systemic lupus erythematosus |
| Investigator(s): | Lau WCS |
| Department: | Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2012 |
| Project Title: | The role of plasmacytoid dendritic cells in systemic lupus erythematosus |
| Investigator(s): | Lau WCS, Chan VSF |
| Department: | Medicine |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2013 |
| Project Title: | The role of regulatory microRNAs in plasmacytoid dendritic cell functions in systemic lupus erythematosus immunopathogenesis |
| Investigator(s): | Lau WCS, Chan VSF |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2013 |
| List of Research Outputs |
| Sharma N., Lau W.C.S., Doherty I. and Harbutt D.D., How we flipped the medical classroom, Medical Teacher. 2014, 1-4. |
| Researcher : Leung GM |
| Project Title: | Evidence-based practice (EBP) learning in the undergraduate medical curriculum - where is the evidence? |
| Investigator(s): | Leung GM, Fielding R, Ho LM, Johnston JM, Lam TH |
| Department: | Community Medicine |
| Source(s) of Funding: | Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants |
| Start Date: | 01/2003 |
| Project Title: | A controlled trial of masks and hand hygiene for reducing influenza transmission |
| Investigator(s): | Leung GM, Cowling BJ, Peiris JSM, Ho LM |
| Department: | Community Medicine |
| Source(s) of Funding: | National Center for Infectious Diseases (NCID) |
| Start Date: | 09/2006 |
| List of Research Outputs |
| Kavikondala S., Ni M.Y., Leung G.M. and Schooling C.M., Social mobility and Adiposity in a Recently Transitioned Population of Hong Kong: Evidence from the FAMILY Cohort (abstract and oral presentation), 47th Annual Society for Epidemiologic Research Meeting, Seattle, USA. 2014. |
| Ni M.Y., Mak S.H.T., Schooling C.M. and Leung G.M., Does where you live matter for health in one of the world’s most densely populated cities? A Multilevel analysis of Neighbourhood cohesion, Population density and Health-Related Quality of Life in the FAMILY Cohort (abstract and oral presentation), 11th International Conference on Urban Health, Manchester, United Kingdom. 2014. |
| TSANG K.L., Cauchemez S., Perera R.A.P.M., Freeman G., Fang J., Ip D.K.M., Leung G.M., Peiris J.S.M. and Cowling B.J., Association between antibody titers and protection against influenza virus infection within households, Journal of Infectious Diseases . 2014, 210(5): 684-92. |
| Xing W., Liao Q., Viboud C., Zhang J., Sun J., Wu J.T.K., Chang Z., Liu F., Fang J., Zheng Y., Cowling B.J., Varma J.K., Farrar J.J., Leung G.M. and Yu H., Hand, foot, and mouth disease in China, 2008–12: an epidemiological study, Lancet Infectious Diseases . 2014, 2014;14: 308-18. |
| Researcher : Li CB |
| Project Title: | A role for oncogenes in the regulation of immune response to Mycobacterial infection |
| Investigator(s): | Li CB |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2010 |
| Project Title: | Cellular Oncogene Dysregulation of Chemokine and Cytokine Expression in Influenza Virus Infection |
| Investigator(s): | Li CB, Leon YY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 09/2011 |
| Project Title: | A role for proto-oncogene c-Myc in antibiotics-sensitive and -resistant bacteria-induced immune responses: a potential building block for the new treatment development |
| Investigator(s): | Li CB |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 12/2011 |
| Project Title: | The role of c-Myc in anti-mycobaterial responses: from bacterial killing to T cell activation |
| Investigator(s): | Li CB, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | The effects of Coriolus Versicolor on TGF-beta induced tumor cell migration |
| Investigator(s): | Li CB |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2014 |
| Researcher : Li G |
| Project Title: | The 10th International Conference on Alzheimer's Disease and Related Disorders High Field MRI Study of the Beta Amyloid and Plaque Desposits in the Brain of APP/PS1 Mice CoQ10 Delays the Brain Atrophy in Transgenic Aged Mice: in Vivo Volume MRI Study |
| Investigator(s): | Li G |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2006 |
| Project Title: | Effect of imbalance of kinases and protein phosphatases on deposit of B amyloid and Tau Pathology in double transgenic APP/PS1 Mice |
| Investigator(s): | Li G, Yang X, Yang ES |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Germany/Hong Kong Joint Research Scheme |
| Start Date: | 01/2007 |
| Researcher : Li RA |
| Project Title: | Cell-based Heart Regeneration |
| Investigator(s): | Li RA, Boheler KR, Chan BP, Chan CWY, Chan GCF, Chien KR, Lee HC, Yue J, Ng RK, Ngan AHW |
| Department: | Medicine |
| Source(s) of Funding: | Theme-based Research Scheme |
| Start Date: | 09/2011 |
| Project Title: | Human WT1 epicardial progenitor cells |
| Investigator(s): | Li RA |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Stem Cell and Regenerative Medicine |
| Investigator(s): | Li RA, Chan GCF, Tse HF |
| Department: | Physiology |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 06/2013 |
| Project Title: | Engineering Calcium Homeostasis of hESC-derived cardiomyocytes |
| Investigator(s): | Li RA |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2013 |
| List of Research Outputs |
| Chow M.Z.Y., Geng L., Kong M.C.W., Keung W.W.Y., Fung J.C., Boheler K.R. and Li R.A., Epigenetic regulation of the electrophysiological phenotype of human embryonic stem cell (hESC)-derived ventricular cardiomyocytes: Insights into driven maturation and hypertrophic growth., Stem Cells Dev. . 2013. |
| Karakikes I.C., Senyei G.D., Kong M.C.W., Lieu D.K., WANG J., Jackson T., Hulot J.S., Li R.A. and Hajjar R.J., Small Molecule-Mediated Directed Differentiation of Human Embryonic Stem Cells Toward Ventricular Cardiomyocytes. Stem Cell Translational Medicine. , Stem Cells Translational Medicine. 2014, 3: 18-31. |
| Li R.A., Advanced Multi-tier Human Pluripotent Stem Cell-Based Platform of 3D Cardiac Ventricular Tissue Constructs as High-Biofidelity In Vitro Diagnostics for Drug Discovery, Cardiotoxicity Screening and Disease Modeling., HKSAR - Karolinska Institutet Visit, Karolinska Institutet, 2014. |
| Li R.A., Cell-based Heart Regeneration, Theme-based Scheme (TRS) Public Symosia, RGC, 2013. |
| Li R.A., 幹細胞的科學與政治: 再造器官是天荒夜譚嗎?, Young Executive Committee luncheon meeting, Chiu Chow Chamber, 2014. |
| Ma X., Du J.R., Zhang P., Deng J., Liu J.S., Lam F. .F. .Y., Li R.A., Huang Y., Jin J. and Yao X., Functional Role of TRPV4-KCa2.3 Signaling in Vascular Endothelial Cells in Normal and Streptozotocin-Induced Diabetic Rats, Hypertension. 2013, 62: 134-139. |
| Poon N.Y.E., Yan B., Zhang S., Keung W.W.Y., Ren L., Geng L., Kong M.C.W., WANG J., Boheler K.R. and Li R.A., Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes., PloS One. . 2013. |
| Researcher : Liu H |
| List of Research Outputs |
| ZHOU J., Cheung K.L.A., Liu H., TAN Z., TANG X., KANG Y., Du Y., Wang H., Liu L. and Chen Z., Potentiating Functional Antigen-specific CD8+ T Cell Immunity by a Novel PD1 Isoform-based Fusion DNA Vaccine, Molecular Therapy. 2013, 21: 1445-1455. |
| Researcher : Liu L |
| Project Title: | Early HIV-1 diagnosis using in-house real-time PCR amplification on dried blood spots for men who have sex with men in Hong Kong |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 09/2009 |
| Project Title: | Identification of small molecule HIV-1 inhibitors with distinct new targets |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 02/2012 |
| Project Title: | The role of HIV-1/SIV Nef in immune activation through regulating the expression of PD-1 and delta-PD-1 |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 03/2012 |
| Project Title: | Molecular mechanisms of Nef mediated regulation of PD-1 expression during HIV/SIV infection |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | A novel small molecule from natural product as a potential agent for purging HIV-1 from the latent reservoir |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2014 |
| List of Research Outputs |
| Liang J., Chen J., Tan Z., Peng J., Zheng X., Nishiura K., Ng J., Wang Z., Wang D., Chen Z. and Liu L., Extracts of medicinal herb Sanguisorba officinalis inhibit the entry of human immunodeficiency virus type one. , JFDA. 2013, 21(4): 52-58. |
| Peng Q., Wang H., Wang H., Li X., LU X., Liu L., Zhou B. and Chen Z., Imbalances of Gut-Homing CD4+ T-Cell Subsets in HIV-1–Infected Chinese Patients, JAIDS Journal of Acquired Immune Deficiency Syndromes. 2013, 64: 25-31. |
| Xiao H., Liu L., Zhu Q., Tan Z., Yu W., Tang X., Zhan D., Du D.Y., Wang H., Liu D., Li Z., Jiang X., Yuen K.Y., Ho D., Gao F. and Chen Z., A Replicating Modified Vaccinia Tiantan Strain Expressing an Avian-Derived Influenza H5N1 Hemagglutinin Induce Broadly Neutralizing Antibodies and Cross-Clade Protective Immunity in Mice, PLoS ONE. 2013, 8: e83274. |
| ZHOU J., Cheung K.L.A., Liu H., TAN Z., TANG X., KANG Y., Du Y., Wang H., Liu L. and Chen Z., Potentiating Functional Antigen-specific CD8+ T Cell Immunity by a Novel PD1 Isoform-based Fusion DNA Vaccine, Molecular Therapy. 2013, 21: 1445-1455. |
| Researcher : Lok S |
| Project Title: | Generation of ferret (Mustela putorius furo) genomic resources for respiratory infectious disease research: Transcriptomics and comprehensive characterization of cDNAs in a model of influenza infection |
| Investigator(s): | Lok S, Tong AHY, Lee MY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 04/2011 |
| List of Research Outputs |
| Seneviratne C.J., Lok S., Tong A., Kot C.C.S., Martelli P., Chan T.F., Yim A.K., Yu C., Zhu L., Samaranayake L.P. and Jin L., Common and specific dental plaque microbiomes of human and giant-panda, Journal of Dental Research. 2013, 92 (Spec Iss B): 724 (APR). |
| Researcher : Ng J |
| List of Research Outputs |
| Liang J., Chen J., Tan Z., Peng J., Zheng X., Nishiura K., Ng J., Wang Z., Wang D., Chen Z. and Liu L., Extracts of medicinal herb Sanguisorba officinalis inhibit the entry of human immunodeficiency virus type one. , JFDA. 2013, 21(4): 52-58. |
| Researcher : Nishiura K |
| List of Research Outputs |
| Liang J., Chen J., Tan Z., Peng J., Zheng X., Nishiura K., Ng J., Wang Z., Wang D., Chen Z. and Liu L., Extracts of medicinal herb Sanguisorba officinalis inhibit the entry of human immunodeficiency virus type one. , JFDA. 2013, 21(4): 52-58. |
| Researcher : Peng Q |
| List of Research Outputs |
| Peng Q., Wang H., Wang H., Li X., LU X., Liu L., Zhou B. and Chen Z., Imbalances of Gut-Homing CD4+ T-Cell Subsets in HIV-1–Infected Chinese Patients, JAIDS Journal of Acquired Immune Deficiency Syndromes. 2013, 64: 25-31. |
| Researcher : Poon NYE |
| Project Title: | The effect of miR-200c on the electrophysiological maturation of human embryonic stem cell derived cardiomyocytes |
| Investigator(s): | Poon NYE, Boheler KR, Li RA |
| Department: | Physiology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2014 |
| List of Research Outputs |
| Poon N.Y.E., Yan B., Zhang S., Keung W.W.Y., Ren L., Geng L., Kong M.C.W., WANG J., Boheler K.R. and Li R.A., Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes., PloS One. . 2013. |
| Researcher : Rong J |
| Project Title: | The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy |
| Investigator(s): | Rong J |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2006 |
| Project Title: | Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) for the resolution of neutrophil-induced myocardial injury |
| Investigator(s): | Rong J, Lau ASY, Li XC, Tse HF, Xia Z |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2012 |
| Project Title: | Regulation of neutrophil survival and migration in ischemic stroke by Chinese medicines Radix Astragali and Radix Paeoniae Rubrae via inducing leukotriene B4 12-hydroxydehydrogenase (LTB4DH) |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2013 |
| Completion Date: | 05/2014 |
| Project Title: | 23rd Neuropharmacology Conference 2013, Sheraton San Diego Hotel and Marina, San Diego, 7 -8 November 2013; Pharmacological induction of arginase II by C-glucosylated isoflavonone puerarin suppresses nitric oxide-induced mitochondrial dysfunction in differentiated neuronal PC12 cells |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 11/2013 |
| Completion Date: | 11/2013 |
| Project Title: | Biological characterization of botanical non-steroidal progesterone receptor modulator puerarin for potentiating nerve growth factor (NGF)-induced neuritogenesis |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2014 |
| Researcher : Sham PC |
| Project Title: | Replication study of susceptibility genes for colorectal cancer |
| Investigator(s): | Sham PC, Ho JWC, Cheng KK |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2007 |
| Project Title: | The State Key Laboratory of Brain and Cognitive Sciences |
| Investigator(s): | Sham PC, So KF, Tan L |
| Department: | Centre for Genomic Sciences |
| Source(s) of Funding: | Matching Fund for State Key Laboratory (SKL) |
| Start Date: | 10/2008 |
| Project Title: | Visiting Research Professors Scheme 2009-10 |
| Investigator(s): | Sham PC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Visiting Research Professors Scheme |
| Start Date: | 09/2009 |
| Project Title: | To determine the functional variants of candidate genes identified by Genome-wide Association Study of Osteoporosis |
| Investigator(s): | Sham PC, Gao RY, Xiao S, Kung AWC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2010 |
| Project Title: | Predicting and preventing schizophrenia in the mouse model. |
| Investigator(s): | Sham PC, Wu EX, McAlonan GM, Cheung C, Chua SE |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2010 |
| Project Title: | Method and Software for Personal Risk Profiling of Complex Diseases |
| Investigator(s): | Sham PC, Cherny SS, Garcia-Barcelo MM, Kung AWC, Li M, Yang W |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2012 |
| Project Title: | Bioinformatics tools for identifying disease loci from exome sequencing data |
| Investigator(s): | Sham PC, Cherny SS, Garcia-Barcelo MM, Li M, Yang W |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Genomics |
| Investigator(s): | Sham PC, Chin FYL, Leung FCC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 06/2013 |
| Project Title: | Statistical methods for characterizing the genetic component of polygenic diseases |
| Investigator(s): | Sham PC, Cherny SS |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Project Title: | Mutational spectrum for dilated cardiomyopathy in Hong Kong |
| Investigator(s): | Sham PC, Tse HF, Cherny SS, Garcia-Barcelo MM, Tang SM, Li M |
| Department: | Centre for Genomic Sciences |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2014 |
| Researcher : Sun W |
| List of Research Outputs |
| Sun W., Yang L.H., Lau A.S.Y. and Li C.B., Inhibitory Effect of Panax Notoginseng (PNG) Extracts on the TNF-α-induced MMP-9 Activity in Cardiomyoblasts, 17th International Congress "PHYTOPHARM 2013". 2013. |
| Researcher : Wang H |
| Project Title: | Induction of gp41-specific IgA to prevent HIV infection. |
| Investigator(s): | Wang H, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2012 |
| Completion Date: | 10/2013 |
| List of Research Outputs |
| Xiao H., Liu L., Zhu Q., Tan Z., Yu W., Tang X., Zhan D., Du D.Y., Wang H., Liu D., Li Z., Jiang X., Yuen K.Y., Ho D., Gao F. and Chen Z., A Replicating Modified Vaccinia Tiantan Strain Expressing an Avian-Derived Influenza H5N1 Hemagglutinin Induce Broadly Neutralizing Antibodies and Cross-Clade Protective Immunity in Mice, PLoS ONE. 2013, 8: e83274. |
| ZHOU J., Cheung K.L.A., Liu H., TAN Z., TANG X., KANG Y., Du Y., Wang H., Liu L. and Chen Z., Potentiating Functional Antigen-specific CD8+ T Cell Immunity by a Novel PD1 Isoform-based Fusion DNA Vaccine, Molecular Therapy. 2013, 21: 1445-1455. |
| Researcher : Wang L |
| List of Research Outputs |
| Ling W.L., Wang L., Pong C.H., Lau A.S.Y. and Li C.B., A ROLE OF INTERLEUKIN-17A IN MODULATING INTRACELLULAR SURVIVAL OF MYCOBACTERIUM BOVIS BCG IN MURINE MACROPHAGES. , The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013. |
| Ling W.L., Wang L., Pong C.H., Chan G.C.F. and Li C.B., Investigating the role of inteleukin-17A on cytokines production by macrophages in response to bacterial infections., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014. |
| Wang L., Lam I.W.T., Ling W.L. and Li C.B., The role of c-Myc in methicillin-resistant staphylococcus aureus induced cytokines production., Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014. |
| Wang L., Ling W.L., Lau A.S.Y. and Li C.B., The role of c-Myc in myocbateria-induced autophagy in human macrophages, Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014. |
| Wang L., Ling W.L., Li C.B. and Lau A.S.Y., The role of c-Myc in phagocytosis of mycobacterial in human macrophages., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013. |
| Wang L., Ling W.L., Lau A.S.Y. and Li C.B., The role of oncogene in mycobacteria-induced autophagy in human macrophages, The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014. |
| Researcher : Wong DSH |
| Project Title: | Inhibition of provisional matrix synthesis in proliferative vitreoretinopathy (PVR) prevention |
| Investigator(s): | Wong DSH, Lo ACY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2008 |
| Project Title: | To introduce bevacizumab for the treatment of macular degeneration and diabetic retinopathy to Queen Mary Hospital |
| Investigator(s): | Wong DSH, Lai WKW, Li KKW |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 03/2008 |
| Project Title: | To develop a tool that can be used to study patients with eye diseases in Hong Kong, namely a translated Chinese version of the established Visual Function Questionnaire (VFQ-25) |
| Investigator(s): | Wong DSH, Lai WKW, McGhee S, Lam CLK, Chan WSC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 07/2008 |
| Project Title: | The Royal College of Ophthalmologists Annual Congress 2009 Can Lutein Protect the Outer Retina? |
| Investigator(s): | Wong DSH |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2009 |
| Project Title: | Effectiveness of lens extraction with intraocular lens implantation for the treatment of primary angle closure glaucoma: A randomized controlled trial (EAGLE) |
| Investigator(s): | Wong DSH, Lai JSM |
| Department: | Ophthalmology |
| Source(s) of Funding: | Medical Research Council (MRC) - General Award |
| Start Date: | 09/2009 |
| Project Title: | Prioritising patients using quality of life and visual acuity: how should we select and prioritise patients for cataract surgery? |
| Investigator(s): | Wong DSH, McGhee S |
| Department: | Ophthalmology |
| Source(s) of Funding: | Health and Health Services Research Fund - Full Grants |
| Start Date: | 03/2012 |
| Project Title: | XXVIIIth Meeting of the Club Jules Gonin WHAT IS THE MOST EFFECTIVE WAY OF PREVENTING EMULSIFICATION OF SILICONE OIL |
| Investigator(s): | Wong DSH |
| Department: | Ophthalmology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2012 |
| Project Title: | To develop a new surgical strategy for removing emulsified droplets in the eye and thereby reducing the complications associated with silicone tamponade. |
| Investigator(s): | Wong DSH |
| Department: | Ophthalmology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Completion Date: | 06/2014 |
| Project Title: | Neuroscience |
| Investigator(s): | Wong DSH, Lee TMC |
| Department: | Ophthalmology |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2013 |
| Project Title: | Randomised double-masked controlled trial of Lutein as an adjunct to surgery to improve the visual outcome of rhegmatogenous retinal detachment |
| Investigator(s): | Wong DSH, McGhee S, Lo ACY, Wong YHI |
| Department: | Ophthalmology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2013 |
| Completion Date: | 08/2014 |
| Project Title: | Diabetic retinopathy screening for specialist care |
| Investigator(s): | Wong DSH, McGhee S, Gangwani RA |
| Department: | Ophthalmology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 06/2014 |
| List of Research Outputs |
| Gangwani R.A., McGhee S., Lam C.L.K., Lai J.S.M. and Wong D.S.H., Prevalence of diabetic retinopathy and sight threatening diabetic retinopathy in Hong Kong. Are we more or less at risk?’ , Hospital Authority Convention 2014, Hong Kong . 2014. |
| Researcher : Yau JMH |
| Project Title: | Angiopoietin-like proteins 3 and 4 as novel inhibitors of lipoprotein lipase: functional and structural studies |
| Investigator(s): | Yau JMH, Xu A, Lam KSL |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2006 |
| Researcher : Yu W |
| List of Research Outputs |
| Xiao H., Liu L., Zhu Q., Tan Z., Yu W., Tang X., Zhan D., Du D.Y., Wang H., Liu D., Li Z., Jiang X., Yuen K.Y., Ho D., Gao F. and Chen Z., A Replicating Modified Vaccinia Tiantan Strain Expressing an Avian-Derived Influenza H5N1 Hemagglutinin Induce Broadly Neutralizing Antibodies and Cross-Clade Protective Immunity in Mice, PLoS ONE. 2013, 8: e83274. |
| Researcher : Zhang M |
| Project Title: | Identification of HIV-1-specific broadly neutralizing human monoclonal antibodies from the B-cell genomic DNA antibody gene repertoires of HIV-1 infected individuals |
| Investigator(s): | Zhang M |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 12/2010 |
| Completion Date: | 11/2013 |
| Project Title: | Reconstitution and Characterization of HIV-specific Antibody Repertoires in vitro: Implications for Passive Immunization |
| Investigator(s): | Zhang M |
| Department: | Microbiology |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 08/2011 |
| Completion Date: | 10/2014 |
| Project Title: | Development of a "Two-in-One" Duel Specific Antibody Therapeutics for Treatment of Breast Cancer |
| Investigator(s): | Zhang M |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 11/2011 |
| Project Title: | Development of intrabodies targeting eukaryotic translation initiation factor 5A2 for cancer treatment |
| Investigator(s): | Zhang M, Guan X |
| Department: | Microbiology |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 06/2012 |
| Completion Date: | 12/2013 |