DEPT OF PAEDIATRICS & ADOLESCENT MED



Researcher : Au KY

List of Research Outputs

Au K.Y., Li C.B. and Lau A.S.Y., Micro-RNAs mediated-regulation of mycobacteria-induced cytokines production, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.
Yang L.H., Law H.Y., Or C.T., Au K.Y., Li C.B. and Lau A.S.Y., Identification of an anti-viral compound with inhibitory effects on influenza replication, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.


Researcher : CHONG CH

List of Research Outputs

CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., Enriched housing condition reduces stressful behavior in Lrrc7 mutant mice, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong, 12-14 June 2014.


Researcher : Chan GCF

Project Title:Review of local experience in the management of childhood myelodysplastic syndrome
Investigator(s):Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Other Funding Scheme
Start Date:01/2001


Project Title:Treatment protocol for childhood medulloblastoma in Hong Kong
Investigator(s):Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Other Funding Scheme
Start Date:01/2001


Project Title:Survey on the prevalence on use of alternative medical treatment in paediatric patients
Investigator(s):Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Other Funding Scheme
Start Date:09/2001


Project Title:Direct generation and functional characterization of human dendritic cells derived from bone marrow cells of leukemic origins
Investigator(s):Chan GCF, Chiu CSW, Ma ESK, Huang F
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Other Funding Scheme
Start Date:07/2002


Project Title:King's/HKU Fellowship Awards 2009-10
Investigator(s):Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:King's/HKU Fellowship Awards
Start Date:09/2009


Project Title:The immunomodulatory effect of artepillin C (Art-C) in experimental autoimmune encephalitis murine models
Investigator(s):Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:05/2014


Project Title:Molecular diagnosis for Childhood Cancers: Defining the Prognosis and Stratifying the Proper Treatments
Investigator(s):Chan GCF, Tam PKH
Department:Paediatrics & Adolescent Med
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2014


Project Title:Human Mesenchymal Stem Cells as a Therapeutic Modality for Graft Versus Host Disease Murine Models
Investigator(s):Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Chan B.P., Chan G.C.F., Wong H.L., Cheung P.T., Cheah K.S.E. and Chan D., 1. Chan BP, GCF Chan, Wong HL, Cheung PT, Cheah K, Chan D. Cell-Matrix Microsphere, Associated Products, Methods for Preparation and Applications. US Regular Patent US 8,679,809 B2 (Patent date: 25 Mar 2014), 2014.
Chan B.P., Cheung K.M.C., Chan G.C.F., Chan D. and Hui T.Y., 2. Chan BP, K Cheung, GCF Chan, D Chan, TY Hui. Bioengineered intervertebral disc and Methods for Their Preparation. US Regular Patent US No. 8,734,827. Patent date: 27 May 2014., US Patent Office. 2014.
Chan B.P., Chan G.C.F., Wong H.L., Cheung P.T., Cheah K.S.E. and Chan D., 3. Chan BP, GCF Chan, Wong HL, Cheung PT, Cheah K, Chan D. Cell-Matrix Microsphere, Associated Products, Methods for Preparation and Applications. PCT Patent Application (filed on 18 May 2007) (Chinese Patent Application No. ZL200780018296.8 filed on 19 November 2009) (Patent granted on 18 December 2013), 2013.
Chan B.P., Wong H.L., Wong M.Y., Wong Y.K. and Chan G.C.F., Interaction with collagen matrix modulates migratory and associated properties in human mesenchymal stem cells (hMSCs)., Gordon Research Conference – Collagen. 14-19 Jul, 2013, NH, USA.. 2013, 11.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.S.W., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Brain tumors of children <18-month-old: A population based study, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.W.S., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Uncommon types of brain tumors among Chinese children, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F. and Chiang A.K.S., 香港大學兒科學系50周年﹕現時香港兒童面對哪些健康威脅, In: RTHK Channel 1, April 29, 2014.
Chan S., Chen M.P., Cao J.M., Chan G.C.F. and Cheung Y.F., Carvedilol protects against iron-induced microparticle generation and apoptosis of endothelial cells, Acta Haematologica . 2014, 132: 200-210.
Chan S.H.S., Tsang D.S.F., Wong V.C.N. and Chan G.C.F., Spinal primitive neuroectodermal tumour mimicking as chronic inflammatory demyelinating polyneuropathy - a case report and review of literatures [Epub ahead of print], Journal of Child Neurology. 2014.
Chan W.Y.K., Cheuk K.L.D., Cheng F.W.T., Ku D.T.L., Shing M.M.K. and Chan G.C.F., Characteristics and outcomes of paediatric renal cell carcinoma in Hong Kong, SIOP Conference 2013. 45th Congress of the International Society of Paediatric Oncology 2013.
Chen M.P., Li S.N., Lam W.W.M., Ho Y.C., Ha S.Y., Chan G.C.F. and Cheung Y.F., Left ventricular torsional mechanics and myocardial iron load in beta-thalassaemia major: a potential role of titin degradation , BMC Cardiovascular Disorders . 2014, 14: 49 (doi:10.1186/1471-2261-14-49.
Cheng F.W.T., Yu C.C.W., Cheuk K.L.D., Li C.H., Chu Y.Y.L., So H.K., Yau J.P.W., Ling A.S.C., Chan G.C.F., LI A.M. and Li C.K., Reduced cardiopulmonary fitness in childhood acute lymphoblastic leukemia survivors, 45th Congress of the International Society of Paediatric Oncology 2013.
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Improving outcomes of hematopoietic stem cell transplant for pediatric acute lymphoblastic leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation for children with acute myeloid leukemia in Hong Kong, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 37.
Cheuk K.L.D., Leung A.W.K., Luk C.W., Li C.H., Ling S.C., Lee V., Ha S.Y., Yuen H.L., Shing M.M.K. and Chan G.C.F., Outcomes of pediatric chronic myeloid leukemia diagnosed in chronic phase in Hong Kong, 45th Congress of the International Society of Paediatric Oncology 2013.
Cheung Y.F., Lam W.W.M., Ip J.J.K., Cheng F.W.T., Yang J.Y.K., Yau J.P.W., Ho K.K.H., Li C.K., Li R.C.H., Yuen H.L., Ling A.S.C., LI W.Y.V. and Chan G.C.F., Cardiac magnetic resonance assessment of myocardial iron load and fibrosis in adult survivors of childhood leukaemias, Pediatric Academic Societies and Asian Society for Pediatric Research Joint Meeting 2014, Vancouver, Canada. 2014.
Cheung Y.F., Yu W., Cheuk K.L.D., Cheng F.W., Yang J.Y., Yau J.P., Ho K.K., Li C.K., Li R.C., Yuen H.L., Ling A.S., Li V.W., Wong W.K., Tsang K.C. and Chan G.C.F., Plasma high sensitivity troponin T levels in adult survivors of childhood leukaemias: determinants and associations with cardiac function, PLos One . 2013, 8: e77063 doi: 10.1371/journal.pone.0077063.
Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Favorable outcomes of unrelated cord blood transplant for pediatric acute myeloid leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Ha S.Y., Xiong H., Cheuk K.L.D., Li H. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation in refractory / relapsed infant leukemia, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Treatment outcome of post-transplant lymphoproliferative disorder in paediatric liver transplant recipients using rituximab-based regimen, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiu S.Y., Chan H.Y., Shum S.K., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiu S.Y., Chan H.Y., Cheuk K.L.D., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Shum S.K., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 78.
Chu C.H., Lee A.H.C., Zheng L., Mei L. and Chan G.C.F., Arresting rampant dental caries with silver diamine fluoride in a young teenager suffering from chronic oral graft versus host disease post-bone marrow transplantation: a case report, BMC Res Notes. 2014, 7: 3.
Fule J.D.R., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Human herpesvirus types 6 and 7 infection in pediatric hematopoietic stem cell transplant recipients, Annals of Transplantation. 2014, 269-276.
Hung C.Y., Chiu S.Y., Shum S.K., Chan H.Y., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Surveillance on central venous catheter complications in paediatric haematology oncology unit, 45th Congress of the International Society of Paediatric Oncology. 2013.
Hung C.Y., Chiu S.Y., Shum S.K., Chan H.Y., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Surveillance on central venous catheter complications in paediatric haematology-oncology unit, European Journal of Oncology Nursing. 2013, 17: 897-898.
LAU K.S., WONG T.W., Ho K.Y., TANG Y.H., ROBLES J.D., WEI X., CHAN C.S., TANG H.L., Lam E.Y.M., Wong K.K.Y., Chan G.C.F., Shum H.C. and Tsia K.K.M., Ultrafast high-contrast microfluidic cellular imaging by asymmetric-detection time-stretch optical microscopy (ATOM), 2013 Frontiers in Optics/Laser Science XXIX (FiO/LS). 2013.
Lau C.S.T., Hansford L.M., Chan W.K., Chan G.C.F., Wan T.S.K., Wong K.K.Y., Kaplan D.R., Tam P.K.H. and Ngan E.S.W., Prokineticin signaling is required for the maintenance of a de novo population of c-KIT positive cells to sustain neuroblastoma progression, Oncogene. 2014.
Li C.K., Ha S.Y., Lee V., Yuen H.L., Li C.H., Ling S.C., Shing M.M.K., Chan G.C.F., Luk C.W., Lee A.C.W., Cheuk K.L.D. and Leung A.W.K., Acute lymphoblastic leukaemia (ALL) in Hong Kong children: treatment outcome from 1993 to 2012, 45th Congress of the International Society of Paediatric Oncology 2013.
Ling W.L., Wang L., Pong C.H., Chan G.C.F. and Li C.B., Investigating the role of inteleukin-17A on cytokines production by macrophages in response to bacterial infections., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K. and Chan G.C.F., Central Nervous System Tumors In Children Under The Age Of Three: A Population Study By The Hong Kong Paediatric Haematology/oncology Study Group, Joint Annual Scientific Meeting 2014 of the Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd . 2014.
Liu A.P.Y., Sing M.M.K., Yuen H.L., Li C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K. and Chan G.C.F., Central Nervous System Tumors in Chinese Children Under The Age of 3, Journal of Pediatric Hematology/Oncology. 2014, 1.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K. and Chan G.C.F., Central nervous system tumors in Chinese children under the age of three: a population study by the Hong Kong Paediatric Haematology/Oncology Study Group, 16th International Symposium on Pediatric Neuro-Oncology, ISPNO 2014.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li R.C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K., Kwong D.L.W. and Chan G.C.F., Timing Of Adjuvant Radiotherapy And Treatment Outcome In Childhood Ependymoma, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li R.C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K., Kwong D.L.W. and Chan G.C.F., Timing of adjuvant radiotherapy and treatment outcome in childhood ependymoma, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 53.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K., Kwong D.L.W. and Chan G.C.F., Timing of adjuvant radiotherapy and treatment outcome in childhood ependymoma, Pediatric Blood & Cancer. 2014, 61: 606-611.
Pong C.H., Chan G.C.F. and Li C.B., HIV-1 Tat dysregulation of KSHV induced immune response through the production of IL-8., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Qiu D., Chan G.C.F., Chu J., Chan Q., Ha S.Y., Moseley M.E. and Khong P.L., MR quantitative susceptibility imaging for the evaluation of iron loading in the brains of patients with B-thalassemia, American Journal of Neuroradiology. 2014, 35(6): 1085-1090.
Tso W.Y.W., Yung A.W.Y., Lau H.Y. and Chan G.C.F., Basal ganglia germinoma: MRI classifications correlates well with neurological and cognitive outcome, Journal of Paediatric Haematology & Oncology. 2013, 36(7): e443-e447.
WONG T.W., Lau K.S.A., Ho K.Y.K., Tang M.Y.H., ROBLES J.D., WEI X., CHAN C.S., TANG H.L., Lam E.Y.M., Wong K.K.Y., Chan G.C.F., Shum H.C. and Tsia K.K.M., Asymmetric-detection time-stretch optical microscopy (ATOM) for ultrafast high-contrast cellular imaging in flow, Scientific Reports. 2014, 4: 3656.
Yu J.L., Khong P.L., Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Cystic-like liver tumours in children: two diseases with similar appearance but required different treatment approach, 45th Congress of the International Society of Paediatric Oncology. 2013.
Yuan L., Chan G.C.F., Fung K.L. and Chim J.C.S., RANKL Expression in Myeloma Cells is regulated by a network involving RANKL promoter methylation, DNMT1, microRNA and TNFα in the Microenvironment, Biochim Biophys Acta - Molecular Cell Research. 2014, 1843(9): 1834-1838.


Researcher : Chan KW

List of Research Outputs

Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L., Chan J.F.W., Woo P.C.Y., Tu W. and Lau Y.L., Penicillium marneffei infection and impaired IFN-γ immunity in humans with autosomal-dominant gain-of-phosphorylation STAT1 mutations, Journal of Allergy and Clinical Immunology. 2013.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.


Researcher : Chan LY

List of Research Outputs

Chan K.P., Wong C.M., Chiu S.S.S., Chan K.H., WANG X., Chan L.Y., Peiris J.S.M. and Yang L., A Robust Parameter Estimation Method for Estimating Disease Burden of Respiratory Viruses, PLOS One. 2014, 9(3): e90126.
Chiu S.S.S., Lo J.Y.C., Chan K.H., Chan L.Y., So L.Y., Wu P., Cowling B.J., Chen H.S.R. and Peiris J.S.M., Population-Based Hospitalization Burden of Influenza A Virus Subtypes and Antigenic Drift Variants in Children in Hong Kong (2004-2011), PLOS One. 2014, 9(4): e92914.


Researcher : Chan PL

List of Research Outputs

Chan P.L., Zheng J., Liu Y., Lam K.T., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One . 2013.
Chan P.L., Zheng J., Liu Y., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One. 2013.
Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


Researcher : Chan PYT

List of Research Outputs

Chan P.Y.T., Ho M.H.K., Cheuk K.L.D., Lee T.L., Ha S.Y. and Lau Y.L., Unrelated cord blood transplantation in a pair of siblings with X-linked severe combined immunodeficiency: the case for early diagnosis and transplant, Hong Kong Journal of Paeditrics. 2014, 19: 32-36.


Researcher : Chan S

List of Research Outputs

Chan S., Chen M.P., Cao J.M., Chan G.C.F. and Cheung Y.F., Carvedilol protects against iron-induced microparticle generation and apoptosis of endothelial cells, Acta Haematologica . 2014, 132: 200-210.


Researcher : Chan SHS

List of Research Outputs

Chan S.H.S., Lo I.F.M., Cherk S., Cheng W.W.S., Fung E., Yeung W.L., Lee W.C., Wong S., Ma C.K.L., Tai S.M., Yau M.M., Ng G., Wu S.P. and Wong V.C.N., A territory wide study for dystrophinopathy in Hong Kong, 18th International congress of the World Muscle Society. October 1st to 6th 2013. (poster presentation) Neuromuscular Disorder. 2013;23(9- 10):776 [Abstract] . 2013, 23(9-10): 776.
Chan S.H.S., Lo I.F.M., Cherk S., Cheng W.W.S., Fung E., Yeung W.L., Lee W.C., Wong S., Ma C.K.L., Tai S.M., Yau M.M., Ng G., Wu S.P. and Wong V.C.N., A territory wide study for dystrophinopathy in Hong Kong, 18th International congress of the World Muscle Society, 1-6 October 2013 [Abstract in Neuromuscular Disord 2013;23(9-10):776. 2013.
Chan S.H.S., Kan S.Y.A. and Tse H.K., An X-linked dominant mutation in LAMP2 causing Danon disease associated with myotonia expanding the spectrum, 18th International congress of the World Muscle Society. October 1st to 6th 2013. (Poster presentation). Neuromuscul Disord. 2013;23(9-10):821 [Abstract] . 2013, 23(9-10): 821.
Chan S.H.S., Kan A. and Tse H.K., An X-linked dominant mutation in LAMP2 causing Danon disease associated with myotonia expanding the spectrum, 18th International congress of the World Muscle Society, 1-6 October 2013.
Chan S.H.S., Chan K.Y., Yau E., Ng G., Wu S.P., Yau M., Fung E., Ngan M., Kwong L., Yau M.M., Ma K.M., Ma C.K., Liu K.T., Cherk S. and Wong V.C.N., Guillain Barre Syndrome (GBS) in children: Diagnosis, management and local case review, 13th Asian Oceanian Myology Meeting, Manila, The Philippines. 14-17 May 2014 (poster presentation). 2014.
Chan S.H.S., Chan K.Y., Yau E., Ng G., Wu S.P., Yau M., Fung E., Ngan M., Kwong L., Yau M.M., Ma K.M., Ma C.K., Liu K.T., Cherk S. and Wong V.C.N., Guillain Barre Syndrome (GBS) in children: Diagnosis, management and local case review, 13th Asian Oceanian Myology Meeting, Manila, Philippine, 14-17 May 2014.
Chan S.H.S., Tsang D.S.F., Wong V.C.N. and Chan G.C.F., Spinal primitive neuroectodermal tumour mimicking as chronic inflammatory demyelinating polyneuropathy - a case report and review of literatures [Epub ahead of print], Journal of Child Neurology. 2014.
Chung B.H.Y., Luk H.M., Chan S.H.S., Shen W.Y. and Hinek A., Phenotypic heterogeneity in 2 sisters with SMAD3-associated aneurysms-osteoarthritis syndrome (AOS) - insights into the pathogenesis from phenotypic assessment and immunohistochemical analysis using patient-derived dermal fibroblasts, 34th Annual David W Smith Workshop, Mont Tremblant, Quebec, Canada, 9-15 August 2013.


Researcher : Chan SY

Project Title:Behavioural phenotyping of a mouse model with social dysfunction
Investigator(s):Chan SY, Li Q
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012
Completion Date:04/2014


Project Title:Effect of the nucleosome assembly protein Tspyl2 in building the epigenetic landscape
Investigator(s):Chan SY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:Gene environment interaction in anxiety and aggressive behaviour
Investigator(s):Chan SY, Li Q
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., Enriched housing condition reduces stressful behavior in Lrrc7 mutant mice, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong, 12-14 June 2014.
LIU H. and Chan S.Y., ChIP-seq Analysis of Histone 3 Lysine 27 Trimethylation (H3K27me3) in Tspyl2 Mutant Mouse Primary Neurons, 18th Research Postgraduate Symposium, the University of Hong Kong (Hong Kong), 11-12 December 2013.
NG C.P., Li Q. and Chan S.Y., The Role of Densin180 in Anxiety Behavior and Protein Distribution, 18th Research Postgraduate Symposium, the University of Hong Kong (Hong Kong), 11-12 December 2013.
SO J., LIU H. and Chan S.Y., Comparison between the Functions of Testis-Specific Protein Y-linked-Like 1 (TSPYL1) and TSPYL2, 18th Research Postgraduate Symposium, the University of Hong Kong (Hong Kong), 11-12 December 2013.
TSANG K.H., Lai S.K., Li Q., Yung W.H., LIU H., Mak H.S., NG C.P., McAlonan G.M., Chan Y.S. and Chan S.Y., The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B, Scientific Reports. 2014, 4: 3654.


Researcher : Chau AKT

List of Research Outputs

Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Liu A.P.Y., Yung T.C., Chau A.K.T. and Chung B.H.Y., Unveiling the genetics of long QT syndrome: A local paediatric experience, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 20.
Liu A.P.Y., Yung T.C., Chau A.K.T. and Chung B.H.Y., Unveiling the genetics of long QT syndrome: a local paediatric experience, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.


Researcher : Chau CSK

List of Research Outputs

Chau C.S.K., Lee S.L., Peiris J.S.M., Chan K.H., Chan E., Wong W.H.S. and Chiu S.S.S., Adenovirus respiratory infection in hospitalized children in Hong Kong: serotype-clinical syndrome association and risk factors for lower respiratory tract infection., Eur J Pediatr. 2013.


Researcher : Chee WYY

List of Research Outputs

YEUNG K.S., Chee W.Y.Y., Luk H.M., Tang M.H.Y., Lau E.T.K., Shuen Y.A., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Evidence of spread of X chromosome inactivation on chromosome 15 in a girl with an unbalanced t(X;15) transolcation, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 64.


Researcher : Chen HSR

List of Research Outputs

Chen H.S.R., Wong S.J., Wong W.H.S. and Cheung Y.F., Arterial mechanics at rest and during exercise in adolescents and young adults after arterial switch operation for complete transposition of the great arteries , Amercian Journal of Cardiology. 2014, 113: 713-718.
Chiu S.S.S., Lo J.Y.C., Chan K.H., Chan L.Y., So L.Y., Wu P., Cowling B.J., Chen H.S.R. and Peiris J.S.M., Population-Based Hospitalization Burden of Influenza A Virus Subtypes and Antigenic Drift Variants in Children in Hong Kong (2004-2011), PLOS One. 2014, 9(4): e92914.


Researcher : Cheuk KLD

List of Research Outputs

Blink M., Zimmermann M., Neuhoff C.V., Reinhardt D., Haas V.D., Hasle H., O'Brien M.M., Stark B., Tandonnet J., Pession A., Tousovska K., Cheuk K.L.D., Kudo K., Taga T., Rubnitz J.E., Haltrich I., Balwierz W., Pieters R., Forestier E., Johnansson B., van den Heuvel-Eibrink M.M. and Zwaan C.M., Normal karyotype is a poor prognostic factor in Myeloid Leukemia of Down Syndrome: a retrospective international study, Haematologica. 2014, 99(2): 299-307.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.S.W., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Brain tumors of children <18-month-old: A population based study, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.W.S., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Uncommon types of brain tumors among Chinese children, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan P.Y.T., Ho M.H.K., Cheuk K.L.D., Lee T.L., Ha S.Y. and Lau Y.L., Unrelated cord blood transplantation in a pair of siblings with X-linked severe combined immunodeficiency: the case for early diagnosis and transplant, Hong Kong Journal of Paeditrics. 2014, 19: 32-36.
Chan W.Y.K., Cheuk K.L.D., Cheng F.W.T., Ku D.T.L., Shing M.M.K. and Chan G.C.F., Characteristics and outcomes of paediatric renal cell carcinoma in Hong Kong, SIOP Conference 2013. 45th Congress of the International Society of Paediatric Oncology 2013.
Cheng F.W.T., Yu C.C.W., Cheuk K.L.D., Li C.H., Chu Y.Y.L., So H.K., Yau J.P.W., Ling A.S.C., Chan G.C.F., LI A.M. and Li C.K., Reduced cardiopulmonary fitness in childhood acute lymphoblastic leukemia survivors, 45th Congress of the International Society of Paediatric Oncology 2013.
Cheng S.H., Lau K.M., Li C.K., Chan N.P.H., Ip R.K.L., Cheng C.K., Lee V., Shing M.M.K., Leung A.W.K., Ha S.Y., Cheuk K.L.D., Lee A.C.W., Li C.H., Luk C.W., Luk C.W., Ling S.C., Hrusak O., Mejstrikova E., Leung Y. and Ng M.H.L., Minimal residual disease-based risk stratification in Chinese childhood acute lymphoblastic leukemia by flow cytometry and plasma DNA quantitative polymerase chain reaction, PLOS One. 2013, 8(7): e69467.
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Improving outcomes of hematopoietic stem cell transplant for pediatric acute lymphoblastic leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Cheuk K.L.D., Optimal stem cell source for allogeneic stem cell transplantation for hematological malignancies, World Journal of Transplantation. 2013, 3(4): 99-112.
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation for children with acute myeloid leukemia in Hong Kong, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 37.
Cheuk K.L.D., Leung A.W.K., Luk C.W., Li C.H., Ling S.C., Lee V., Ha S.Y., Yuen H.L., Shing M.M.K. and Chan G.C.F., Outcomes of pediatric chronic myeloid leukemia diagnosed in chronic phase in Hong Kong, 45th Congress of the International Society of Paediatric Oncology 2013.
Cheung Y.F., Yu W., Cheuk K.L.D., Cheng F.W., Yang J.Y., Yau J.P., Ho K.K., Li C.K., Li R.C., Yuen H.L., Ling A.S., Li V.W., Wong W.K., Tsang K.C. and Chan G.C.F., Plasma high sensitivity troponin T levels in adult survivors of childhood leukaemias: determinants and associations with cardiac function, PLos One . 2013, 8: e77063 doi: 10.1371/journal.pone.0077063.
Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Favorable outcomes of unrelated cord blood transplant for pediatric acute myeloid leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Ha S.Y., Xiong H., Cheuk K.L.D., Li H. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation in refractory / relapsed infant leukemia, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Ling S., Li C., Yuen H., Cheuk K.L.D., Li C. and Li C., Population-based treatment results of hepatoblastoma in children of Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Lee V., Yuen H., Li C., Ling S., Cheuk K.L.D. and Lee A.C., Results of a uniform treatment protocol based on the ALCL99 study for anaplastic large cell lymphoma in children and adolescents of Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Lee V., Yuen H., Li C., Ling S., Cheuk K.L.D. and Lee A.C., Results of a uniform treatment protocol based on the FAB/LMB96 study for B cell non-hodgkin lymphoma in children and adolescents of Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Lee V., Yuen H.L., Li C.H., Ling S.C., Cheuk K.L.D. and Lee A.C.W., Results of treatment of lymphoblastic lymphoma in children and adolescents of Hong Kong, 45th Congress of the International Society of Paediatric Oncology 2013.
Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Treatment outcome of post-transplant lymphoproliferative disorder in paediatric liver transplant recipients using rituximab-based regimen, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiu S.Y., Chan H.Y., Shum S.K., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiu S.Y., Chan H.Y., Cheuk K.L.D., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Shum S.K., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 78.
Fule J.D.R., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Human herpesvirus types 6 and 7 infection in pediatric hematopoietic stem cell transplant recipients, Annals of Transplantation. 2014, 269-276.
Hung C.Y., Chiu S.Y., Shum S.K., Chan H.Y., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Surveillance on central venous catheter complications in paediatric haematology oncology unit, 45th Congress of the International Society of Paediatric Oncology. 2013.
Hung C.Y., Chiu S.Y., Shum S.K., Chan H.Y., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Surveillance on central venous catheter complications in paediatric haematology-oncology unit, European Journal of Oncology Nursing. 2013, 17: 897-898.
Lee V., Luk C.W., Cheuk K.L.D., Li C.H., Ling S.C., Leung A.W.K., Yuen H.L., Chiang A.K.S. and Shing M.M.K., Long term treatment outcome of conventional high grade osteosarcoma in Hong Kong children and adolescents – from the Hong Kong paediatric haematology and oncology study group, 45th Congress of the International Society of Paediatric Oncology. 2013.
Li C.H., Lam E., Lee M., Cheng F.W.T., Cheuk K.L.D., Yau J.P.W. and Ling S.C., Psychosocial outcomes in long term survivors of childhood cancer in Hong Kong, 45th Congress of the International Society of Paediatric Oncology 2013.
Li C.K., Ha S.Y., Lee V., Yuen H.L., Li C.H., Ling S.C., Shing M.M.K., Chan G.C.F., Luk C.W., Lee A.C.W., Cheuk K.L.D. and Leung A.W.K., Acute lymphoblastic leukaemia (ALL) in Hong Kong children: treatment outcome from 1993 to 2012, 45th Congress of the International Society of Paediatric Oncology 2013.
Yu J.L., Khong P.L., Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Cystic-like liver tumours in children: two diseases with similar appearance but required different treatment approach, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Cheung PT

Project Title:The Endocrine Society 83rd Annual Meeting Mutations of the CYP11B2 Gene in a Patient with Corticosterone Methyl Oxidase Type II Deficiency
Investigator(s):Cheung PT
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2001


Project Title:International Perinatal Collegium 2005 Meeting New Approaches in Old Models - Identification of Novel Molecular Alterations in Neonatal Mouse Hypoxic-Ischaemic Brain Damage
Investigator(s):Cheung PT
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2005


Project Title:4th Asian Epigenomics Meeting Methyl mercury induced epigenetic dysregulation of BDNF gene in NG108 cells in vitro – a possible mechanism of environment-epigenome interactions underlying neuropsychiatric and neurodevelopmental disorders.
Investigator(s):Cheung PT
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2009


Project Title:9th Joint Meeting of Paediatric Endocrinology; Effective treatment with low dose dihydrotestosterone gel on three Chinese boys with 5-alpha-reductase II deficiency
Investigator(s):Cheung PT
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2013


List of Research Outputs

Chan B.P., Chan G.C.F., Wong H.L., Cheung P.T., Cheah K.S.E. and Chan D., 1. Chan BP, GCF Chan, Wong HL, Cheung PT, Cheah K, Chan D. Cell-Matrix Microsphere, Associated Products, Methods for Preparation and Applications. US Regular Patent US 8,679,809 B2 (Patent date: 25 Mar 2014), 2014.
Chan B.P., Chan G.C.F., Wong H.L., Cheung P.T., Cheah K.S.E. and Chan D., 3. Chan BP, GCF Chan, Wong HL, Cheung PT, Cheah K, Chan D. Cell-Matrix Microsphere, Associated Products, Methods for Preparation and Applications. PCT Patent Application (filed on 18 May 2007) (Chinese Patent Application No. ZL200780018296.8 filed on 19 November 2009) (Patent granted on 18 December 2013), 2013.
Hui Y.L.E., Yeung M.C., Cheung P.T., Kwan E.Y.W., Tan K.C.B., Lam K.S.L. and Chan A.O.K., The clinical significance of aldosterone synthase deficiency: report of a novel mutation in the CYP11B2 gene., BMC Endocrine Disorder.. 2014, 14: 29.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Serum Level of Sex Hormone-Binding Globulin Is a Good Independent Predictor of Metabolic Syndrome in Women with Polycystic Ovary Syndrome, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo. 2014.


Researcher : Cheung YF

Project Title:CSX/NKX2.5 mutations in patients with pulmonary atresia and intact ventricular septum
Investigator(s):Cheung YF, Chan SY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Development of a multimedia tool for teaching of paediatric cardiology
Investigator(s):Cheung YF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:04/2004


Project Title:Neo-Aortic Root Stiffness following Arterial Switch Operation: Relationship with Neo-Aortic Root Dilatation and Regurgitation
Investigator(s):Cheung YF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:05/2012
Completion Date:10/2013


Project Title:Arterial-Ventriculo-Atrial Interaction in Patients After Surgical Repair of Coarctation of the Aorta
Investigator(s):Cheung YF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:Right and Left Atrial Function in Patients After Surgical Repair of Tetralogy of Fallot
Investigator(s):Cheung YF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:01/2014


Project Title:Circulating MicroRNAs and Myocardial Damage in Paediatric Cancer Patients Receiving Anthracyline Therapy
Investigator(s):Cheung YF, Cheuk KLD, Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:03/2014


Project Title:Pediatric Academic Societies and Asian Society for Pediatric Research Joint Meeting 2014; Cardiac magnetic resonanec assessment of myocardial iron load and fibrosis in adult survivors of childhood leukaemias
Investigator(s):Cheung YF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2014
Completion Date:05/2014


List of Research Outputs

Chan S., Chen M.P., Cao J.M., Chan G.C.F. and Cheung Y.F., Carvedilol protects against iron-induced microparticle generation and apoptosis of endothelial cells, Acta Haematologica . 2014, 132: 200-210.
Chen H.S.R., Wong S.J., Wong W.H.S. and Cheung Y.F., Arterial mechanics at rest and during exercise in adolescents and young adults after arterial switch operation for complete transposition of the great arteries , Amercian Journal of Cardiology. 2014, 113: 713-718.
Chen M.P., Li S.N., Lam W.W.M., Ho Y.C., Ha S.Y., Chan G.C.F. and Cheung Y.F., Left ventricular torsional mechanics and myocardial iron load in beta-thalassaemia major: a potential role of titin degradation , BMC Cardiovascular Disorders . 2014, 14: 49 (doi:10.1186/1471-2261-14-49.
Cheung Y.F., Acyanotic Congenital Heart Disease Heart Failure in Children, First Affiliated Hospital of Sun Yat-sen University,Guangzhou, 2014.. 2014.
Cheung Y.F., Advances in assessment of ventricular function in congenital heart disease, Symposium on Congenital Heart Diseases – From Prenatal Diagnosis to Motherhood, Department of Obstetrics & Gynaecology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 2013. 2013.
Cheung Y.F., Aortic root dilation in congenital heart disease , The 19th Chinese Pediatric Cardiology Conference, He Fei, An Hui Province, Shanghai, 19 to 21 June 2014. 2014.
Cheung Y.F., Lam W.W.M., Ip J.J.K., Cheng F.W.T., Yang J.Y.K., Yau J.P.W., Ho K.K.H., Li C.K., Li R.C.H., Yuen H.L., Ling A.S.C., LI W.Y.V. and Chan G.C.F., Cardiac magnetic resonance assessment of myocardial iron load and fibrosis in adult survivors of childhood leukaemias, Pediatric Academic Societies and Asian Society for Pediatric Research Joint Meeting 2014, Vancouver, Canada. 2014.
Cheung Y.F., Congenital Heart Disease: Aetiology, Presentation, and Diagnosis, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 2014.. 2014.
Cheung Y.F., Cyanotic Congenital Heart Disease, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 2014. . 2014.
Cheung Y.F., Functional assessment for congenital heart disease , Korean Circulation Journal . 2014, 44: 59-73.
Cheung Y.F., Genetics of Kawasaki Disease, China-Japan Pediatric Cardiac Forum of Shanghai Children's Hospital, Shanghai, June 12 - 13, 2014. 2014.
Cheung Y.F., Highest ranking abstract submitted from Hong Kong “Cardiac magnetic resonance assessment of myocardial iron load and fibrosis in adult survivors of childhood leukaemias”, American College of Cardiology’s Annual Scientific Sessions in Washington, DC. . 2014.
Cheung Y.F., How should a child with severe left ventricular dysfunction be investigated? , The 5th Congress of Asia Pacific Pediatric Cardiac Surgery (APPCS) March 6 to 9 2014, New Delhi, India. 2014.
Cheung Y.F., Kawasaki disease: a risk for accelerated atherosclerosis?, 2nd Oriental Congress of Pediatrics, Shanghai, Oct 17 to 20, 2013. 2013.
Cheung Y.F., Management of Congenital Heart Disease, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 2014.. 2014.
Cheung Y.F., Novel three-dimensional wall motion tracking: potential applications in paediatric cardiac failure, 1st Beijing International Forum of Pediatric Development, Beijing, 7 - 11 Nov 2013. 2013.
Cheung Y.F., Yu W., Cheuk K.L.D., Cheng F.W., Yang J.Y., Yau J.P., Ho K.K., Li C.K., Li R.C., Yuen H.L., Ling A.S., Li V.W., Wong W.K., Tsang K.C. and Chan G.C.F., Plasma high sensitivity troponin T levels in adult survivors of childhood leukaemias: determinants and associations with cardiac function, PLos One . 2013, 8: e77063 doi: 10.1371/journal.pone.0077063.
Cheung Y.F., Pulmonary arterial hypertension - What's new? , Update in Paediatric Respiratory Diseases 2013, 2 November 2013. 2013.
Cheung Y.F., Sharing of Experience in Doing and Publishing Paediatric Cardiovascular Clinical Research, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 2014. . 2014.
Cheung Y.F., Strain, strain rate in congenital heart disease, The 49th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery, Japan, 11-13 July 2013. 2013.
Cheung Y.F. and Hou J., Travel Award (supervisor of Dr Hou Jia) Atrial Mechanics in Patients After Surgical Repair of Tetralogy of Fallot, The 49th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery. 2013.
Cheung Y.F., 剖析川崎症患者常見有關心臟的併發症 , 2013年第三季季度講座, 香港風濕病基金會, 2013.
Cheung Y.F., 中華醫學科技獎, 川崎病冠狀動脈病變的流行病學臨床處理及預測指標研究, 2013.
Hou J., Yu H.K., Wong S.J. and Cheung Y.F., Atrial mechanics after surgical repair of tetralogy of Fallot, Echocardiography . 2014, 00: 1-9 (DOI:10.1111/echo.12611).
Hou J. and Cheung Y.F., Atrial mechanics in patients after surgical repair of tetralogy of Fallot, The 49th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery, Japan, July 11 - 13, 2013.
LAI C.T.M. and Cheung Y.F., Determinants of plasma levels of high sensitivity cardiac troponin T in adults with repaired tetralogy of Fallot , The 49th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery, Japan, July 11 - 13, 2013.
LI W.Y.V. and Cheung Y.F., Right ventricular mechanics in adolescents and young adults late after repair of coarctation of the aorta, 63rd Annual Scientific Session & Expo, Washington, USA. 2014.
Lai C.T.M., Ng E.K., Chow P.C., Kwong A. and Cheung Y.F., Circulating microRNA expression profile and systemic right ventricular function in adults after atrial switch operation for complete transposition of the great arteries, BMC Cardiovasc Disord . 2013, 13: 73 doi:10.1186/1471-2261-13-73.
Li S., Wong S.J. and Cheung Y.F., Atrial an ventricular mechanics in patients after Fontan-type procedures: atriopulmonary connection versus extracardiac conduit, 63rd Annual Scientific Session & Expo, Washington, USA. 2014.
Li S.J., Wong S.J. and Cheung Y.F., Atrial and ventricular mechanics in patients after fontan-type procedures: atriopulmonary connection versus extracardiac conduit, Journal of American Society of Echocardiography. 2014, 2014: doi.org/10.1016/j.echo.2014.01.027.
Li S.J., Yu H.K., Wong S.J. and Cheung Y.F., Right and left ventricular mechanics and interaction late after ballon valvoplasty for pulmonary stenosis , European Heart Journal - Cardiovascular Imaging . 2014, doi:10.1093/ehjci/jeu058.
Li S.N., Yu W., Lai C.T.M., Wong S.J. and Cheung Y.F., Left ventricular mechanics in repaired tetralogy of Fallot with and without pulmonary valve replacement: analysis by three-dimensional speckle tracking echocardiography, PLoS One . 2013, 8: e78826 doi:10.1371/journal.pone.0078826.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Tsang F.H.F., Chow P.C., Ma Y.Y., Man K., Cheng L.C. and Cheung Y.F., Apoptosis of cardiomyocytes in children with right ventricular pressure overload with and without hypoxemia, J Card Surg. 2014, 1-6 (doi:10.1111/jocs.12337).


Researcher : Chiang AKS

Project Title:Genetic studies of tubercubosis
Investigator(s):Chiang AKS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Other Funding Scheme
Start Date:03/2002


Project Title:Prospective study of virologic and immunologic parameters of primary Epstein-Barr virus infection in Chinese children
Investigator(s):Chiang AKS, Chan KH
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2003


Project Title:Prospective study of Epstein-Barr virus (EBV) strains in primary EBV infection
Investigator(s):Chiang AKS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Longitudinal study of Epstein-Barr virus specific antibody responses in childhood infectious mononucleosis
Investigator(s):Chiang AKS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:12/2005


Project Title:Longitudinal study of Epstein-Barr virus-specific T cell immunity in post-transplant lymphoproliferative disorder
Investigator(s):Chiang AKS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2012
Completion Date:05/2014


Project Title:Investigating the function and maturation of Epstein-Barr virus (EBV)-specific T cell responses in patients with EBV-associated haemophagocytic lymphohistiocytosis
Investigator(s):Chiang AKS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:American Association for Cancer Research Annual Meeting 2014; Proteasome inhibitor synergizes with histone deacetylase inhibitor to trigger ROS- and ER stress-induced apoptosis of nasopharyngeal carcinoma independent of aggresome disruption
Investigator(s):Chiang AKS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2014
Completion Date:04/2014


Project Title:Effects of romidepsin on induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies
Investigator(s):Chiang AKS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:04/2014


List of Research Outputs

Attarbaschi A., Beishuizen A., Mann G., Rosolen A., Mori T., Uyttebroeck A., Niggli F., Csoka M., Krenova Z., Mellgren K., Kabickova E., Chiang A.K.S., Reiter A., Williams D. and Burkhardt B., Children and adolescents with follicular lymphoma have an excellent prognosis with either limited chemotherapy or with a “watch and wait” strategy after complete resection, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.S.W., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Brain tumors of children <18-month-old: A population based study, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.W.S., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Uncommon types of brain tumors among Chinese children, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F. and Chiang A.K.S., 香港大學兒科學系50周年﹕現時香港兒童面對哪些健康威脅, In: RTHK Channel 1, April 29, 2014.
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Improving outcomes of hematopoietic stem cell transplant for pediatric acute lymphoblastic leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation for children with acute myeloid leukemia in Hong Kong, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 37.
Chiang A.K.S., Clinical spectrum and biology of Epstein-Barr virus related lymphoproliferative disorders(EB病毒相關淋巴细胞增殖性疾病的臨床及生物學特性), Guangdong Anticancer Association Paediatric Oncology Specialist Committee, Paediatric Lymphoma Diagnose Senior Traning (廣東省抗癌協會小兒腫瘤專業委員會兒童淋巴瘤診治高級培訓班), Guang Zhou, China. 2013.
Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Favorable outcomes of unrelated cord blood transplant for pediatric acute myeloid leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S. and Godzinski J., Free Paper Session 24 – Renal and Sarcomas III, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Ha S.Y., Xiong H., Cheuk K.L.D., Li H. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation in refractory / relapsed infant leukemia, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Overview of Diagnosis and Treatment of Paediatric Liver Tumours, International Society of Paediatric Surgical Oncology (IPSO) Pre-Congress Education Day, Hong Kong. 2013.
Chiang A.K.S., Ling S., Li C., Yuen H., Cheuk K.L.D., Li C. and Li C., Population-based treatment results of hepatoblastoma in children of Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S. and Hui K.F., Proteasome inhibitor synergizes with histone deacetylase inhibitor to trigger ROS- and ER stress-induced apoptosis of nasopharyngeal carcinoma independent of aggresome disruption, In: Chiang AKS, Hui KF, AACR Annual Meeting 2014.
Chiang A.K.S., Recent advances in the management of childhood non-Hodgkin lymphomas(兒童非霍奇金淋巴瘤診治進展), Guangdong Anticancer Association Paediatric Oncology Specialist Committee, Paediatric Lymphoma Diagnose Senior Traning(廣東省抗癌協會小兒腫瘤專業委員會兒童淋巴瘤診治高級培訓班), Guang Zhou, China. 2013.
Chiang A.K.S., Lee V., Yuen H., Li C., Ling S., Cheuk K.L.D. and Lee A.C., Results of a uniform treatment protocol based on the ALCL99 study for anaplastic large cell lymphoma in children and adolescents of Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Lee V., Yuen H., Li C., Ling S., Cheuk K.L.D. and Lee A.C., Results of a uniform treatment protocol based on the FAB/LMB96 study for B cell non-hodgkin lymphoma in children and adolescents of Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Lee V., Yuen H.L., Li C.H., Ling S.C., Cheuk K.L.D. and Lee A.C.W., Results of treatment of lymphoblastic lymphoma in children and adolescents of Hong Kong, 45th Congress of the International Society of Paediatric Oncology 2013.
Chiang A.K.S., Yuen A.N.Y., Ho S.M.Y., Chan C.K.Y., Lee V., Yuen H.L. and Ling S.C., The relationship between hope, rumination response styles, rumination content and psychological adjustment among childhood cancer patients and survivors, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Mak N.K. and Ng W.T., Translational research in nasopharyngeal carcinoma, Oral Oncology. 2014, 345-352.
Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Treatment outcome of post-transplant lymphoproliferative disorder in paediatric liver transplant recipients using rituximab-based regimen, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Tumour board meeting (case discussion), International Society of Paediatric Surgical Oncology (IPSO) Pre-Congress Education Day, Hong Kong. 2013.
Chiu S.Y., Chan H.Y., Shum S.K., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiu S.Y., Chan H.Y., Cheuk K.L.D., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Shum S.K., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 78.
Fule J.D.R., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Human herpesvirus types 6 and 7 infection in pediatric hematopoietic stem cell transplant recipients, Annals of Transplantation. 2014, 269-276.
Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Combination of Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, In: Hui KF, Leung YY, Yeung PL, Chiang AKS, EBV 50th Anniversary. 2014.
Hui K.F. and Chiang A.K.S., Combination of proteasome and class I HDAC inhibitors induces apoptosis of NPC cells through an HDAC6-independent ER stress-induced mechanism, International Journal of Cancer. 2014.
Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, Hong Kong College of Paediatricians, Annual Scientific Meeting. 2013.
Hung C.Y., Chiu S.Y., Shum S.K., Chan H.Y., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Surveillance on central venous catheter complications in paediatric haematology oncology unit, 45th Congress of the International Society of Paediatric Oncology. 2013.
Hung C.Y., Chiu S.Y., Shum S.K., Chan H.Y., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Surveillance on central venous catheter complications in paediatric haematology-oncology unit, European Journal of Oncology Nursing. 2013, 17: 897-898.
LEUNG Y.Y., HUI K.F. and Chiang A.K.S., Effects of histone deacetylase inhibitor and proteasome inhibitor on Epstein-Barr Virus-Positive burkitt cells and lymphoblastoid cell lines, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 19.
Lee V., Luk C.W., Cheuk K.L.D., Li C.H., Ling S.C., Leung A.W.K., Yuen H.L., Chiang A.K.S. and Shing M.M.K., Long term treatment outcome of conventional high grade osteosarcoma in Hong Kong children and adolescents – from the Hong Kong paediatric haematology and oncology study group, 45th Congress of the International Society of Paediatric Oncology. 2013.
NING J., Chan K.H. and Chiang A.K.S., Development of immunodominance hierarchies concurrent with enhanced polyfunctionality in T cell immunity towards Epstein - Barr virus, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 60.
Yu J.L., Khong P.L., Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Cystic-like liver tumours in children: two diseases with similar appearance but required different treatment approach, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Chim D

List of Research Outputs

Sobowale K., Zhou N., Van Voorhees B.W., Stewart S., Tsang A.M.C., Ip P., Fabrizio C., Wong K.L. and Chim D., Adaptation of an internet-based depression prevention intervention for Chinese adolescents: from "CATCH-IT" to "grasp the opportunity", Internationl Journal of Adolescent Medicine and Health . 2013, 25: 127-137.


Researcher : Chiu IWS

List of Research Outputs

Chiu I.W.S., Chow C.B., Ip P., Ho K.W. and Wong W.H.S., Injuries among children 0 to 19 years in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 38.
Ho K.W., Chow C.B., Ip P., Leung M., Chow Y.H., Yeung A., Wong W.H.S. and Chiu I.W.S., Creating safe playgrounds: A safety promotion approach, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 45.
Ip P., Lam T.H., Chan S.S.C., Ho K.W., Lo L.A., Chiu I.W.S., Wong W.H.S. and Chow C.B., Use of Internet viral marketing to promote smoke-free lifestyles among Chinese adolescents, PLoS One. 2014, 9: e99082.


Researcher : Chiu SSS

Project Title:Streptococcus pneumoniae carriage in young children in Hong Kong
Investigator(s):Chiu SSS, Ho PL
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:10/1999


Project Title:Impact of universal vaccination with the 7-valent conjugate pneumocccal vaccine (PCV7) in Hong Kong on the incidence of pneumonia hospitalization and carriage in children
Investigator(s):Chiu SSS, Ho PL
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Centre for Health Protection
Start Date:07/2010


List of Research Outputs

Chan K.P., Wong C.M., Chiu S.S.S., Chan K.H., WANG X., Chan L.Y., Peiris J.S.M. and Yang L., A Robust Parameter Estimation Method for Estimating Disease Burden of Respiratory Viruses, PLOS One. 2014, 9(3): e90126.
Chau C.S.K., Lee S.L., Peiris J.S.M., Chan K.H., Chan E., Wong W.H.S. and Chiu S.S.S., Adenovirus respiratory infection in hospitalized children in Hong Kong: serotype-clinical syndrome association and risk factors for lower respiratory tract infection., Eur J Pediatr. 2013.
Chiu S.S.S., Lo J.Y.C., Chan K.H., Chan L.Y., So L.Y., Wu P., Cowling B.J., Chen H.S.R. and Peiris J.S.M., Population-Based Hospitalization Burden of Influenza A Virus Subtypes and Antigenic Drift Variants in Children in Hong Kong (2004-2011), PLOS One. 2014, 9(4): e92914.
Chiu S.S.S., Streptococcus pneumonia serotype 19A bacteremia in a child fully immunized with 10-valent pneumococcal conjugate vaccine, Journal of Microbiology, Immunology and Infection. 2014, 47: 164-165.


Researcher : Chong CY

List of Research Outputs

ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Chow CB

Project Title:Use of Internet marketing in promotion of smoking cessation among youths in Hong Kong
Investigator(s):Chow CB, Ip P, Lam TH, Chan SSC
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:07/2012
Completion Date:10/2013


Project Title:A geographical study of child injury in Hong Kong: Spatial variation among 18 districts
Investigator(s):Chow CB, Ip P, Wong WHS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Health Care and Promotion Fund - Research Grant Projects
Start Date:09/2013


List of Research Outputs

Chan E.K.L., Choi W.M.A., Fong D.Y.T., Chow C.B., Leung M. and Ip P., Violence: Recognition, Management, and Prevention. Characteristics of Family Violence Victims Presenting to Emergency Departments in Hong Kong, The Journal of Emergency Medicine . 2013, 44: 249-258.
Chiu I.W.S., Chow C.B., Ip P., Ho K.W. and Wong W.H.S., Injuries among children 0 to 19 years in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 38.
Chung B.H.Y., Ip P. and Chow C.B., 醫健寶庫: 醫管局助找濫藥孕婦, 2014.
Gale S.C., Ip P., Chow C.B., Wong W.H.S., Chung B.H.Y. and Ip D.K.M., An estimate of the prevalence of down's syndrome in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 42.
Gale S.C., Chu W.Y., Ip P., Chow C.B., Wong W.H.S., Ip D.K.M. and Chung B.H.Y., Factors influencing length of stay amongst people with down's syndrome, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 43.
Ho K.W., Chow C.B., Ip P., Leung M., Chow Y.H., Yeung A., Wong W.H.S. and Chiu I.W.S., Creating safe playgrounds: A safety promotion approach, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 45.
Ip P., Chan E.K.L., Chow C.B. and Wong W.H.S., Executive Summary of Epidemiology of Child Abuse and Its Geographic Distribution in Hong Kong: An Important Social Indicator of Different Districts and Communities (A Central Policy Unit Commissioned Report), 2013.
Ip P., Chan E.K.L., Chow C.B. and Wong W.H.S., Executive Summary of Epidemiology of Child Abuse and Its Geographic Distribution in Hong Kong: An Important Social Indicator of Different Districts and Communities (A Central Policy Unit Commissioned Report). Aug 2013, 2013.
Ip P., Lam T.H., Chan S.S.C., Ho K.W., Lo L.A., Chiu I.W.S., Wong W.H.S. and Chow C.B., Use of Internet viral marketing to promote smoke-free lifestyles among Chinese adolescents, PLoS One. 2014, 9: e99082.
Ip P., Li L., Rao N., Ng S...S...N., Lau W.S. and Chow C.B., Validation study of the Chinese Early Development Instrument (CEDI), BMC Pediatrics. London, BioMed Central, 2013, 13:146.


Researcher : Chow PC

List of Research Outputs

Lai C.T.M., Ng E.K., Chow P.C., Kwong A. and Cheung Y.F., Circulating microRNA expression profile and systemic right ventricular function in adults after atrial switch operation for complete transposition of the great arteries, BMC Cardiovasc Disord . 2013, 13: 73 doi:10.1186/1471-2261-13-73.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Tsang F.H.F., Chow P.C., Ma Y.Y., Man K., Cheng L.C. and Cheung Y.F., Apoptosis of cardiomyocytes in children with right ventricular pressure overload with and without hypoxemia, J Card Surg. 2014, 1-6 (doi:10.1111/jocs.12337).


Researcher : Chu WY

List of Research Outputs

Chu W.Y., Wong W.L. and Chung B.H.Y., What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(1): 41.
Chung B.H.Y. and Chu W.Y., Inheritance and risk assessment, Commissioned Program - Clinical Genetics and Genetic Counseling for Nurses, Seminar A - Clinical Genetics in Paediatrics, 20-22 January 2014.
Chung B.H.Y., Chu W.Y. and Lee W.M., Paediatric counseling & scenarios, Commissioned Program - Clinical Genetics and Genetic Counseling for Nurses, Seminar A - Clinical Genetics in Paediatrics, 20-22 January 2014.
Gale S.C., Chu W.Y., Ip P., Chow C.B., Wong W.H.S., Ip D.K.M. and Chung B.H.Y., Factors influencing length of stay amongst people with down's syndrome, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 43.
Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.
Luk H.M., Wong V.C.H., Lo I.F.M., Chan Y.K., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Tang W.F., She W.M.K., Chu W.Y., Sin W.K. and Chung B.H.Y., A prenatal case of split-hand malformation associated with 17p13.3 triplication – A dilemma in genetic counseling, European Journal of Medical Genetics. Elsevier, 2014, 57: 81-84.
Mok T.K.G., Chu W.Y., Tan T.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(2): 129.
Mok W.K.Y., Wong W.H.S., Chu W.Y., Chung B.H.Y. and Ip P., Health-related quality of life of Chinese individuals with down syndrome in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 55.
Mok W.K.Y., Chu W.Y., Wong W.H.S., Ip P., Zayts O.A. and Chung B.H.Y., What should be said an what should not be said> - Perception of parents and caregivers of individuals with down syndrome in Hong Kong on sensitive language in Cantonese used in healthcare setting, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 39.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
Tao Q.V., She W., Chu W.Y., Tso W.Y.W., Chan K.Y., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 23.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 36.


Researcher : Chung BHY

Project Title:Genome-wide DNA methylation profiling in Chinese patients with Systemic Lupus Erythematosus (SLE)
Investigator(s):Chung BHY, Lau YL, Yang W
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2011
Completion Date:08/2013


Project Title:Provision of molecular diagnosis for patients with birth defects/genetic conditions in Hong Kong
Investigator(s):Chung BHY, Lau YL, Yang W
Department:Paediatrics & Adolescent Med
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:02/2012


Project Title:Identification of Epigenetic alterations in Imprinting Growth disorders
Investigator(s):Chung BHY, Chan KW, Wong KY, Li RHW, Tang MHY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2012
Completion Date:05/2014


Project Title:Comprehensive genetic evaluation of children with autism spectrum disorders in Hong Kong
Investigator(s):Chung BHY, Wong VCN, Lee SL, Fung CW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2012


Project Title:Copy-number variations in Chinese patients with conotruncal defects - a pilot study of 100 patients
Investigator(s):Chung BHY, Liu APY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Children's Heart Foundation - General Award
Start Date:03/2013


Project Title:Identification of DNA methylation changes in Chinese patients with early-onset Systemic Lupus Erthematosus by bisulfite-converted DNA pyrosequencing
Investigator(s):Chung BHY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:34th Annual David W. Smith Workshop on Malformations and Morphogenesis; Phenotypic heterogeneity in 2 sisters with SMAD3-associated aneurysms-osteoarthritis syndrome (AOS) - insights into the pathogenesis from phenotypic assessment and immunohistochemical analysis using patient-derived dermal fibroblasts
Investigator(s):Chung BHY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


Project Title:Cell lineage-specific differential DNA methylation in Chinese patients with early-onset systemic lupus erythematosus: implications for disease susceptibility
Investigator(s):Chung BHY, Lau YL, Yang W, Lee PPW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Genomic Medicine for All - State of Art Testing for Hong Kong Children with Genetic Conditions
Investigator(s):Chung BHY, Lau YL, Yang W, Sham PC, Chan YK
Department:Paediatrics & Adolescent Med
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2014


Project Title:Does the pattern of X Inactivation affect the phenotypic severity of patients with Triple X (XXX) syndrome?
Investigator(s):Chung BHY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:05/2014


List of Research Outputs

AU YEUNG K.Y.G., Zayts O.A., Sarangi S.K. and Chung B.H.Y., With others and for others: Accounting for decisions about genetic testing in the clinic , 12th International Conference Communication, Medicine and Ethics. Lugano, Switzerland. 2014.
AU YEUNG K.Y.G., Zayts O.A., Sarangi S. and Chung B.H.Y., With others and for others: Accounting for decisions about genetic testing in the clinic, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 19.
Chan T.K., Hui E. and Chung B.H.Y., A child born with Edward's syndrome: the legal and moral duty to accede to the request for parentage determination, Journal of Medical Ethics. 2014, 40: 383-386.
Choufani S., Cytrynbaum C., Turinsky A.L., Chen Y.A., Grafodatskaya D., Xiang J., Feigenberg M., Chung B.H.Y., Stavropoulos D.J., Mendoza R., Gibson W.T., Reardon M., Brudno M. and Weksberg R., A specific DNA methylation signature associated with NSD1+/- mutations in Sotos syndrome reveals a significant genome-wide loss of DNA methylation (DNAm) targeting CGs in regulatory regions of key developmental genes, American Society of Human Genetics, Boston, USA, 22-26 October 2013.
Chu W.Y., Wong W.L. and Chung B.H.Y., What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(1): 41.
Chung B.H.Y., ABC of Clinical Genetics, Update on Clinical Genetics - From Bench to Bedside, 19 January 2014.
Chung B.H.Y., 自閉症遺傳學, AM730 paper, 4 November 2013. 2013.
Chung B.H.Y., Adjudicators, Joint Annual Scientific Meeting 2014, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd., 15 June 2014. 2014.
Chung B.H.Y., Application of next generation sequencing in genetic clinics in Hong Kong, Special VCGS seminar, Victorian Clinical Genetics Services, Murdon Childrens Research Institute, Australia, 31 July 2013.
Chung B.H.Y., Are XXX / XXY / XYY associated with mental or behavioral abnormalities?, Clinical Genetics Symposium Series S4, Sex Chromosome Abnormalities and Disorders of Sexual Development, 6-7 July 2013. 2013.
Chung B.H.Y., Clinical Genetics - Understanding the discipline from a dental perspective, Lecture presentation to Clinical Staff from School of Dental Care Services, Hong Kong, 8-9 October 2013. 2013.
Chung B.H.Y., Clinical Genetics Symposium Series S4, Sex Chromosome Abnormalities and Disorders of Sexual Development, 6-7 July 2013. 2013.
Chung B.H.Y., Clinical application of whole genome technologies in paediatrics - hopes and hurdles, 20th Anniversary Congress, Hong Kong Academy of Medicine, 8-11 December 2013. 75.
Chung B.H.Y., Clinical approach on skeletal dysplasia from the viewpoint of clinical genetics, The 1st Gachon Skeletal Dysplasia Symposium, Korea, 31 May 2014.
Chung B.H.Y., Co-Chairperson, 6th International Conference on Birth Defects and Disabilities in the Developing World, S3-13 – Enchancing skeletal birth defects diagnosis: management and prevention, Philippines, 12 November 2013. 2013.
Chung B.H.Y., Common Genetic Disease in Children & Genetic Counselling, The Core Module of the Post-registration Certificate Course in Paediatric Specialty Nursing. 2014.
Chung B.H.Y., Common Genetic Syndromes in Paediatric Practice, 2014 Paediatric Update No. 1 - Paediaric Genetics / Genomics, HK, 27 April 2014. 2014.
Chung B.H.Y., Editorial Board Member, Hong Kong Journal of Paediatrics, 2014-2017. 2014.
Chung B.H.Y., Genetic counseling and medical care for Down syndrome in Hong Kong, 2014 World Down Syndrome Day International Symposium, Taipei, Kaohsiung, Taiwan, 21-24 March 2014. 2014.
Chung B.H.Y., Genetics of Cardiac Channelopathies, Genetics of heart disease in children. 小儿心脏病学进展 (2), 2014.
Chung B.H.Y., Genetics of Connective Tissue Vascular Diseases, Genetics of heart disease in children. 小儿心脏病学进展 (2), 2014.
Chung B.H.Y., 應否為自己及兒童做遺傳測試, HSSC Bioethics Forum, HSSC Bioethics Resources Centre, 11 June 2014. 2014.
Chung B.H.Y., Bradley T., Grosse-Wortmann L., Blaser S., Dirks P., Hinek A. and Chitayat D., Hand and fibrillin-1 deposition abnormalities in Loeys–Dietz syndrome—expanding the clinical spectrum, American Journal of Medical Genetics (Part A). Wiley, 2014, 146(2): 461-466.
Chung B.H.Y., Health care needs and utilization of patients with Down syndrome in Hong Kong, 2014 World Down Syndrome Day International Symposium, Taipei, Kaohsiung, Taiwan, 21-24 March 2014. 2014.
Chung B.H.Y., Identification of 22q11.2 deletion in patients from adult congenital heart disease clinic - a missed burden in the transition care in Hong Kong, American Society of Human Genetics (ASHG), San Digeo, USA, 22-26 October 2013.
Chung B.H.Y., Identification of genetic disorders in Hong Kong - a tailor-made approach, 6th International Conference on Birth Defects and Disabilities in the Developing World, Philippines, 12 November 2013. 2013.
Chung B.H.Y. and Chu W.Y., Inheritance and risk assessment, Commissioned Program - Clinical Genetics and Genetic Counseling for Nurses, Seminar A - Clinical Genetics in Paediatrics, 20-22 January 2014.
Chung B.H.Y., 探討遺傳測試議題 生命倫理小組講座, Kung Kao Po, 29 June 2014. 2014.
Chung B.H.Y., Making interdisciplinary research work - thoughts from the field, Sciences of Learning Strategic Research Theme, 12 May, 2014. 2014.
Chung B.H.Y., Metabolic emergencies in the neonatal period, 13th Perinatal Symposium 2013, Topic in Perinatal Medicine, 26 October 2013. 2013.
Chung B.H.Y., New Insight of Common Child Health Diseases in the Context of Epigenetics, C.M.E. in Obstetrics & Gynaecology, Hong Kong Sanatorium & Hospital, Hong Kong, 24 October 2013. 2013.
Chung B.H.Y., New insight of common child health diseases in the context of epigenetics, Danone Baby Nutrition (HK) Limited, Sheraton Hong Kong Hotel & Tower, Hong Kong, 23 October 2013. 2013.
Chung B.H.Y., Next generation sequencing from the clinical geneticist perspective, Strategic Research Theme of Development and Reproduction, Centre for Reproduction, Development and Growth, Joint Research Retreat, HKU-SZ Hospital, 14 September 2013. 2013.
Chung B.H.Y., Paediatric Genetics - All About the "Next Generation", Li Shu Pui Symposium 2013 - Recent advances in medical practice, HK Sanatorium Hospital, 15 September 2013. 2013.
Chung B.H.Y., Chu W.Y. and Lee W.M., Paediatric counseling & scenarios, Commissioned Program - Clinical Genetics and Genetic Counseling for Nurses, Seminar A - Clinical Genetics in Paediatrics, 20-22 January 2014.
Chung B.H.Y., Luk H.M., Chan S.H.S., Shen W.Y. and Hinek A., Phenotypic heterogeneity in 2 sisters with SMAD3-associated aneurysms-osteoarthritis syndrome (AOS) - insights into the pathogenesis from phenotypic assessment and immunohistochemical analysis using patient-derived dermal fibroblasts, 34th Annual David W Smith Workshop, Mont Tremblant, Quebec, Canada, 9-15 August 2013.
Chung B.H.Y., 罕有骨骼疾病 (軟骨發育不全, 脆骨病), RTHK Radio 1 Health Programme (Rare Disease), 11 March 2014. 2014.
Chung B.H.Y., Reviewer "BMG Genetics". 2014.
Chung B.H.Y., Reviewer "BMJ case report". 2014.
Chung B.H.Y., Reviewer "Gene". 2014.
Chung B.H.Y., Reviewer "PLOS One". 2014.
Chung B.H.Y., Reviewer, Hong Kong Journal of Paediatrics. 2013.
Chung B.H.Y., Reviewer, Journal of Pediatric Genetics. 2014.
Chung B.H.Y., Reviewer, The Diagnostic Pathology. 2013.
Chung B.H.Y. and Tan T.Y., Similarities and Differences in Medical Genetic Practice in Asia and Australasia: Cross-Cultural Genetic Counselling Experiences in Hong Kong, China, HGSA (Human Genetics Society of Australasia), Queenstown, New Zealand, 4-7 August 2013.
Chung B.H.Y., Two challenging patients with chromosome 15 translocation - how do the clinical geneticist and the cytogeneticist work as a team?, 2013 Annual General Meeting and Scientific Seminar, Hong Kong Society of Cytogenetics, 25 September 2013. 2013.
Chung B.H.Y., Update of Genetics in Paediatrics, Medical Specialties Summit, Association of Private Medical Specialists of Hong Kong, 26 October 2013. 2013.
Chung B.H.Y., With others and for others: Accounting for decisions about genetic testing in the clinic, COMET 2014, Switzerland. 2014.
Chung B.H.Y., Ip P. and Chow C.B., 醫健寶庫: 醫管局助找濫藥孕婦, 2014.
Chung B.H.Y. and Yung T.C., 遺傳性心律失常猝死綜合症, 香港電台精靈一點, 24 June 2014, 2014.
Gale S.C., Ip P., Chow C.B., Wong W.H.S., Chung B.H.Y. and Ip D.K.M., An estimate of the prevalence of down's syndrome in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 42.
Gale S.C., Chu W.Y., Ip P., Chow C.B., Wong W.H.S., Ip D.K.M. and Chung B.H.Y., Factors influencing length of stay amongst people with down's syndrome, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 43.
Inbar-Feigenberg M., Grafodatskaya D., Choufani S., Chung B.H.Y., Roberts L.J., Russell C., Roberts W., Hamilton J. and Weksberg R., Social skills impairments in girls with Turner syndrome, American Society of Human Genetics (ASHG), San Digeo, USA, 22-26 October 2013.
Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.
Leung W.Y., Liu A.P.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2013, 18: 182.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Liu A.P.Y., Yung T.C., Chau A.K.T. and Chung B.H.Y., Unveiling the genetics of long QT syndrome: A local paediatric experience, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 20.
Liu A.P.Y., Yung T.C., Chau A.K.T. and Chung B.H.Y., Unveiling the genetics of long QT syndrome: a local paediatric experience, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.
Lo I.F.M., Leung K.C., Luk H.M.M., Wong W.L., Tang L.Y.F., Chu Y.W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Chan Y.K. and Chung B.H.Y., Massive parallel sequencing for the genetic diagnosis of rasopathies – a study of 58 Chinese patients in Hong Kong. , Poster presentation in CCMG Annual Meeting, 2013.. 2013.
Luk H.M., Wong V.C.H., Lo I.F.M., Chan Y.K., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Tang W.F., She W.M.K., Chu W.Y., Sin W.K. and Chung B.H.Y., A prenatal case of split-hand malformation associated with 17p13.3 triplication – A dilemma in genetic counseling, European Journal of Medical Genetics. Elsevier, 2014, 57: 81-84.
Mok T.K.G., Chu W.Y., Tan T.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(2): 129.
Mok W.K.Y., Wong W.H.S., Chu W.Y., Chung B.H.Y. and Ip P., Health-related quality of life of Chinese individuals with down syndrome in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 55.
Mok W.K.Y., Chu W.Y., Wong W.H.S., Ip P., Zayts O.A. and Chung B.H.Y., What should be said an what should not be said> - Perception of parents and caregivers of individuals with down syndrome in Hong Kong on sensitive language in Cantonese used in healthcare setting, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 39.
Rosenfeld J.A., Stoate K., Asamoah A., Lebel R.R., Raskin S., Russell L., Chitayat D., Chung B.H.Y., Ellison J.W. and Schimmenti L.A., In the shadow of MEF2C: Genotype-phenotype correlation for 5q14.3q21 deletions, American Society of Human Genetics (ASHG), San Digeo, USA, 22-26 October 2013.
She W.M.K., Liu A.P.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). Medcom Limited, 2013, 18: 266-267.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
Tao Q.V., She W., Chu W.Y., Tso W.Y.W., Chan K.Y., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 23.
YEUNG K.S., Chee W.Y.Y., Luk H.M., Tang M.H.Y., Lau E.T.K., Shuen Y.A., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Evidence of spread of X chromosome inactivation on chromosome 15 in a girl with an unbalanced t(X;15) transolcation, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 64.
YEUNG K.S., Choufani S., Chen Y.A., Grafodatskaya D., Lee P.P.W., Yang W., Weksberg R., Lau Y.L. and Chung B.H.Y., Genome-wide DNA Methylation Analysis of Hong Kong Chinese Systemic Lupus Erythematosus Patients identified Hypomethylated Genes Related to Type I Interferon, Epigenomics of Common Diseases, Wellcome Trust Conference Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK, 7-10 November 2013.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 36.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.
Zayts O.A., Sarangi S., Thong M.K., Chung B.H.Y., Lo F.M., Kan S.Y.A., Lee M.H., Padilla C.D., Cutiongco-de la Paz E.M., Faradz M.H.S. and Wasant P., Genetic counseling/consultation in South-East Asia: A report from the workshop at the 10th Asia Pacific Conference on Human Genetics, Journal of Genetic Counseling . 2013, 22 (6): 917-924.
Zayts O.A. and Chung B.H.Y., Interdisciplinary collaboration between medical professionals and sociolinguists, Sciences of Learning Strategic Research Theme seminar, the University of Hong Kong . 2014.
Zeng S., Yang J., Chung B.H.Y., Lau Y.L. and Yang W., EFIN: predicting the functional impact of nonsynonymous single nucleotide polymorphisms in human genome, BMC Genomics. 2014, 15: 455-463.


Researcher : Fung CW

List of Research Outputs

Ho C.C.A., Kwong K.Y., Fung C.W. and Wong V.C.N., Clinical And Genetic Evaluation Of 23 Children With Infantile Onset Epileptic Encephalopathy (iee), The 3rd Hong Kong Neurological Congress Cum 26th Annual Scientific Meeting Of The Hong Kong Neurological Society. 2-3 November, 2013. (Free Paper award). 2013.
Ho C.C.A., Fung C.W., Siu T.S., Ma O.C.K., Lam C.W., Tam S. and Wong V.C.N., Lathosterolosis: A Disorder Of Cholesterol Biosynthesis Resembling Smith-lemli-opitz Syndrome, Journal Of Inherited Metabolic Disease . 2014, 12: 129-134.
Tso W.W.Y., Kwong K.Y., Wong V.C.N. and Fung C.W., Folinic acid responsive epilepsy in Ohtahara syndrome caused by STXBP1 mutation., Pediatric Neurology. 2014.. 2013, 50: 177-180.
Tso W.Y.W., Kwong A.K., Fung C.W. and Wong V.C.N., Folinic acid responsive epilepsy in Ohtahara Syndrome caused by STXBP1 mutation, Pediatric Neurology. 2014, 50(2): 177-180.


Researcher : Fung KL

List of Research Outputs

Yuan L., Chan G.C.F., Fung K.L. and Chim J.C.S., RANKL Expression in Myeloma Cells is regulated by a network involving RANKL promoter methylation, DNMT1, microRNA and TNFα in the Microenvironment, Biochim Biophys Acta - Molecular Cell Research. 2014, 1843(9): 1834-1838.


Researcher : HAN Y

List of Research Outputs

HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.


Researcher : HUI KF

List of Research Outputs

Chiang A.K.S. and Hui K.F., Proteasome inhibitor synergizes with histone deacetylase inhibitor to trigger ROS- and ER stress-induced apoptosis of nasopharyngeal carcinoma independent of aggresome disruption, In: Chiang AKS, Hui KF, AACR Annual Meeting 2014.
Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Combination of Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, In: Hui KF, Leung YY, Yeung PL, Chiang AKS, EBV 50th Anniversary. 2014.
Hui K.F. and Chiang A.K.S., Combination of proteasome and class I HDAC inhibitors induces apoptosis of NPC cells through an HDAC6-independent ER stress-induced mechanism, International Journal of Cancer. 2014.
Hui K.F., Outstanding Oral Presentation Award, Hong Kong College of Paediatricians, Annual Scientific Meeting 2013. 2013.
Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, Hong Kong College of Paediatricians, Annual Scientific Meeting. 2013.
LEUNG Y.Y., HUI K.F. and Chiang A.K.S., Effects of histone deacetylase inhibitor and proteasome inhibitor on Epstein-Barr Virus-Positive burkitt cells and lymphoblastoid cell lines, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 19.


Researcher : Ha SY

List of Research Outputs

Chan P.Y.T., Ho M.H.K., Cheuk K.L.D., Lee T.L., Ha S.Y. and Lau Y.L., Unrelated cord blood transplantation in a pair of siblings with X-linked severe combined immunodeficiency: the case for early diagnosis and transplant, Hong Kong Journal of Paeditrics. 2014, 19: 32-36.
Cheng S.H., Lau K.M., Li C.K., Chan N.P.H., Ip R.K.L., Cheng C.K., Lee V., Shing M.M.K., Leung A.W.K., Ha S.Y., Cheuk K.L.D., Lee A.C.W., Li C.H., Luk C.W., Luk C.W., Ling S.C., Hrusak O., Mejstrikova E., Leung Y. and Ng M.H.L., Minimal residual disease-based risk stratification in Chinese childhood acute lymphoblastic leukemia by flow cytometry and plasma DNA quantitative polymerase chain reaction, PLOS One. 2013, 8(7): e69467.
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Improving outcomes of hematopoietic stem cell transplant for pediatric acute lymphoblastic leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation for children with acute myeloid leukemia in Hong Kong, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 37.
Cheuk K.L.D., Leung A.W.K., Luk C.W., Li C.H., Ling S.C., Lee V., Ha S.Y., Yuen H.L., Shing M.M.K. and Chan G.C.F., Outcomes of pediatric chronic myeloid leukemia diagnosed in chronic phase in Hong Kong, 45th Congress of the International Society of Paediatric Oncology 2013.
Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Favorable outcomes of unrelated cord blood transplant for pediatric acute myeloid leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Ha S.Y., Xiong H., Cheuk K.L.D., Li H. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation in refractory / relapsed infant leukemia, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Treatment outcome of post-transplant lymphoproliferative disorder in paediatric liver transplant recipients using rituximab-based regimen, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiu S.Y., Chan H.Y., Shum S.K., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiu S.Y., Chan H.Y., Cheuk K.L.D., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Shum S.K., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 78.
Fule J.D.R., Cheuk K.L.D., Ha S.Y., Chiang A.K.S. and Chan G.C.F., Human herpesvirus types 6 and 7 infection in pediatric hematopoietic stem cell transplant recipients, Annals of Transplantation. 2014, 269-276.
Ha S.Y., Lee V., Li C.H., Luk C.W., Ling S.C., Cheuk D.K.L., Shing M.M.K. and Li C.K., Comparison of two consecutive cohorts of childhood acute myeloid leukemia in Hong Kong, 45th Congress of the International Society of Paediatric Oncology 2013.
Hung C.Y., Chiu S.Y., Shum S.K., Chan H.Y., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Surveillance on central venous catheter complications in paediatric haematology oncology unit, 45th Congress of the International Society of Paediatric Oncology. 2013.
Hung C.Y., Chiu S.Y., Shum S.K., Chan H.Y., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Surveillance on central venous catheter complications in paediatric haematology-oncology unit, European Journal of Oncology Nursing. 2013, 17: 897-898.
Li C.K., Ha S.Y., Lee V., Yuen H.L., Li C.H., Ling S.C., Shing M.M.K., Chan G.C.F., Luk C.W., Lee A.C.W., Cheuk K.L.D. and Leung A.W.K., Acute lymphoblastic leukaemia (ALL) in Hong Kong children: treatment outcome from 1993 to 2012, 45th Congress of the International Society of Paediatric Oncology 2013.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li R.C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K., Kwong D.L.W. and Chan G.C.F., Timing of adjuvant radiotherapy and treatment outcome in childhood ependymoma, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 53.
Qiu D., Chan G.C.F., Chu J., Chan Q., Ha S.Y., Moseley M.E. and Khong P.L., MR quantitative susceptibility imaging for the evaluation of iron loading in the brains of patients with B-thalassemia, American Journal of Neuroradiology. 2014, 35(6): 1085-1090.
Yu J.L., Khong P.L., Chiang A.K.S., Cheuk K.L.D., Ha S.Y. and Chan G.C.F., Cystic-like liver tumours in children: two diseases with similar appearance but required different treatment approach, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Ho CCA

List of Research Outputs

Ho C.C.A., Kwong K.Y., Fung C.W. and Wong V.C.N., Clinical And Genetic Evaluation Of 23 Children With Infantile Onset Epileptic Encephalopathy (iee), The 3rd Hong Kong Neurological Congress Cum 26th Annual Scientific Meeting Of The Hong Kong Neurological Society. 2-3 November, 2013. (Free Paper award). 2013.
Ho C.C.A., Fung C.W., Siu T.S., Ma O.C.K., Lam C.W., Tam S. and Wong V.C.N., Lathosterolosis: A Disorder Of Cholesterol Biosynthesis Resembling Smith-lemli-opitz Syndrome, Journal Of Inherited Metabolic Disease . 2014, 12: 129-134.


Researcher : Ho KW

List of Research Outputs

Chiu I.W.S., Chow C.B., Ip P., Ho K.W. and Wong W.H.S., Injuries among children 0 to 19 years in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 38.
Ho K.W., Chow C.B., Ip P., Leung M., Chow Y.H., Yeung A., Wong W.H.S. and Chiu I.W.S., Creating safe playgrounds: A safety promotion approach, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 45.
Ip P., Lam T.H., Chan S.S.C., Ho K.W., Lo L.A., Chiu I.W.S., Wong W.H.S. and Chow C.B., Use of Internet viral marketing to promote smoke-free lifestyles among Chinese adolescents, PLoS One. 2014, 9: e99082.


Researcher : Ho MHK

List of Research Outputs

Chan P.Y.T., Ho M.H.K., Cheuk K.L.D., Lee T.L., Ha S.Y. and Lau Y.L., Unrelated cord blood transplantation in a pair of siblings with X-linked severe combined immunodeficiency: the case for early diagnosis and transplant, Hong Kong Journal of Paeditrics. 2014, 19: 32-36.
Chellapandian D., Das R., Zelley K., Wiener S.J., Zhao H., Teachey D.T., Nichols K.E. and Ho M.H.K., Treatment of Epstein Barr virus-induced haemophagocytic lymphohistiocytosis with rituximab-containing chemo-immunotherapeutic regimens, British Journal of Haematology. 2013, 162(3): 376-382.
Ho M.H.K., 適量用類固醇 無懼副作用, Oriental Daily News, 19 October 2013. 2013.
Ho M.H.K., 踢爆有機食物謬誤 冇證據治食物敏感, 蘋果日報, 2014.
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L., Chan J.F.W., Woo P.C.Y., Tu W. and Lau Y.L., Penicillium marneffei infection and impaired IFN-γ immunity in humans with autosomal-dominant gain-of-phosphorylation STAT1 mutations, Journal of Allergy and Clinical Immunology. 2013.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.
Yang J., Lee P.P.W., Ying D., Ho M.H.K., Lee T.L., Yang W. and Lau Y.L., Molecular diagnosis for paediatric genetic disorders using whole exome sequencing of the next generation sequencing technology, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 17.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Hou J

List of Research Outputs

Hou J. and Cheung Y.F., Atrial mechanics in patients after surgical repair of tetralogy of Fallot, The 49th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery, Japan, July 11 - 13, 2013.


Researcher : Hui KF

Project Title:Investigation of histone modification on induction of Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma
Investigator(s):Hui KF, Chiang AKS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:02/2013
Completion Date:07/2014


List of Research Outputs

Chiang A.K.S. and Hui K.F., Proteasome inhibitor synergizes with histone deacetylase inhibitor to trigger ROS- and ER stress-induced apoptosis of nasopharyngeal carcinoma independent of aggresome disruption, In: Chiang AKS, Hui KF, AACR Annual Meeting 2014.
Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Combination of Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, In: Hui KF, Leung YY, Yeung PL, Chiang AKS, EBV 50th Anniversary. 2014.
Hui K.F. and Chiang A.K.S., Combination of proteasome and class I HDAC inhibitors induces apoptosis of NPC cells through an HDAC6-independent ER stress-induced mechanism, International Journal of Cancer. 2014.
Hui K.F., Outstanding Oral Presentation Award, Hong Kong College of Paediatricians, Annual Scientific Meeting 2013. 2013.
Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, Hong Kong College of Paediatricians, Annual Scientific Meeting. 2013.
LEUNG Y.Y., HUI K.F. and Chiang A.K.S., Effects of histone deacetylase inhibitor and proteasome inhibitor on Epstein-Barr Virus-Positive burkitt cells and lymphoblastoid cell lines, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 19.


Researcher : Ip P

Project Title:The Gap Between the Rich and the Poor: From School Readiness to School Success
Investigator(s):Ip P, Bacon-Shone J, Rao N, Vere JP
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Can physical activity enhance sleep quality among adolescents? A randomised controlled trial
Investigator(s):Ip P
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Bray M., Chen E., Ip P., Lee D., Rao N., Shaeffer S., Sun J., Weekes B., Wong J. and Young M., Early Childhood Development and Cognitive Deveolpment in Developing Countries: A Rigorous Literature Review. Initial Report submitted to Department for International Department in 2013. , 2013.
Chan D.F.Y., Lau T., Wong W.H.S., Ip P., Kwong N.S. and Li C.K., Cluster evaluation on teenage pregnancy management in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 31.
Chan E.K.L., Choi W.M.A., Fong D.Y.T., Chow C.B., Leung M. and Ip P., Violence: Recognition, Management, and Prevention. Characteristics of Family Violence Victims Presenting to Emergency Departments in Hong Kong, The Journal of Emergency Medicine . 2013, 44: 249-258.
Chiu I.W.S., Chow C.B., Ip P., Ho K.W. and Wong W.H.S., Injuries among children 0 to 19 years in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 38.
Chung B.H.Y., Ip P. and Chow C.B., 醫健寶庫: 醫管局助找濫藥孕婦, 2014.
Gale S.C., Ip P., Chow C.B., Wong W.H.S., Chung B.H.Y. and Ip D.K.M., An estimate of the prevalence of down's syndrome in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 42.
Gale S.C., Chu W.Y., Ip P., Chow C.B., Wong W.H.S., Ip D.K.M. and Chung B.H.Y., Factors influencing length of stay amongst people with down's syndrome, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 43.
Ho K.W., Chow C.B., Ip P., Leung M., Chow Y.H., Yeung A., Wong W.H.S. and Chiu I.W.S., Creating safe playgrounds: A safety promotion approach, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 45.
Ip P., Chan E.K.L., Chow C.B. and Wong W.H.S., Executive Summary of Epidemiology of Child Abuse and Its Geographic Distribution in Hong Kong: An Important Social Indicator of Different Districts and Communities (A Central Policy Unit Commissioned Report), 2013.
Ip P., Chan E.K.L., Chow C.B. and Wong W.H.S., Executive Summary of Epidemiology of Child Abuse and Its Geographic Distribution in Hong Kong: An Important Social Indicator of Different Districts and Communities (A Central Policy Unit Commissioned Report). Aug 2013, 2013.
Ip P., Lam T.H., Chan S.S.C., Ho K.W., Lo L.A., Chiu I.W.S., Wong W.H.S. and Chow C.B., Use of Internet viral marketing to promote smoke-free lifestyles among Chinese adolescents, PLoS One. 2014, 9: e99082.
Ip P., Li L., Rao N., Ng S...S...N., Lau W.S. and Chow C.B., Validation study of the Chinese Early Development Instrument (CEDI), BMC Pediatrics. London, BioMed Central, 2013, 13:146.
Ip P., 醫管局助找濫藥孕婦 (Oriental Daily News), 2014.
Li S.L., Lau Y.L., Lam T.H., Yip P.S.F., Fan S.Y.S. and Ip P., HPV vaccination in Hong Kong: Uptake and reasons for non-vaccination amongst Chinese adolescent girls, Vaccine. 2013, 31: 5785-5788.
Man K.C.K., Ip P., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W., Chow C., Yung A. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder Drug Prescribing Trend is Increasing Among Children and Adolescents in Hong Kong: 2001-2012, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
Man K.C.K., Chan E.W., Douglas I., Ip P., Wong W.H.S., Coghill D. and Wong I.C.K., Attention-Deficit/Hyperactivity disorder (ADHD) Pharmacological Treatment and its Effect on Accident and Emergency Admission due to injury: a self-controlled case series study., 3rd EUNETHYDIS, Istanbul, Turkey, 21-24 May . 2014.
Mok W.K.Y., Wong W.H.S., Chu W.Y., Chung B.H.Y. and Ip P., Health-related quality of life of Chinese individuals with down syndrome in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 55.
Mok W.K.Y., Chu W.Y., Wong W.H.S., Ip P., Zayts O.A. and Chung B.H.Y., What should be said an what should not be said> - Perception of parents and caregivers of individuals with down syndrome in Hong Kong on sensitive language in Cantonese used in healthcare setting, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 39.
Rao N., Sun J., Wong J.M.S., Weekes B.S., Ip P., Sheldon S., Young M., Bray T.M., Chen E. and Lee P.L.D., Early Childhood Development And Cognitive Development In Developing Countries: A Rigorous Literature Review, Department for International Development. 2013.
Rao N., Sun J., Wong J.M.S., Weekes B.S., Ip P., Sheldon S., Young M., Bray T.M. and Chen E., Early Childhood Development And Cognitive Development In Developing Countries: A Rigorous Literature Review, Department for International Development, United Kingdom. 2013.
Sobowale K., Zhou N., Van Voorhees B.W., Stewart S., Tsang A.M.C., Ip P., Fabrizio C., Wong K.L. and Chim D., Adaptation of an internet-based depression prevention intervention for Chinese adolescents: from "CATCH-IT" to "grasp the opportunity", Internationl Journal of Adolescent Medicine and Health . 2013, 25: 127-137.


Researcher : Kwan EYW

List of Research Outputs

Hui Y.L.E., Yeung M.C., Cheung P.T., Kwan E.Y.W., Tan K.C.B., Lam K.S.L. and Chan A.O.K., The clinical significance of aldosterone synthase deficiency: report of a novel mutation in the CYP11B2 gene., BMC Endocrine Disorder.. 2014, 14: 29.


Researcher : Kwong KY

List of Research Outputs

Ho C.C.A., Kwong K.Y., Fung C.W. and Wong V.C.N., Clinical And Genetic Evaluation Of 23 Children With Infantile Onset Epileptic Encephalopathy (iee), The 3rd Hong Kong Neurological Congress Cum 26th Annual Scientific Meeting Of The Hong Kong Neurological Society. 2-3 November, 2013. (Free Paper award). 2013.
Tso W.W.Y., Kwong K.Y., Wong V.C.N. and Fung C.W., Folinic acid responsive epilepsy in Ohtahara syndrome caused by STXBP1 mutation., Pediatric Neurology. 2014.. 2013, 50: 177-180.


Researcher : Kwong L

List of Research Outputs

Chan S.H.S., Chan K.Y., Yau E., Ng G., Wu S.P., Yau M., Fung E., Ngan M., Kwong L., Yau M.M., Ma K.M., Ma C.K., Liu K.T., Cherk S. and Wong V.C.N., Guillain Barre Syndrome (GBS) in children: Diagnosis, management and local case review, 13th Asian Oceanian Myology Meeting, Manila, The Philippines. 14-17 May 2014 (poster presentation). 2014.


Researcher : LAI CTM

List of Research Outputs

LAI C.T.M. and Cheung Y.F., Determinants of plasma levels of high sensitivity cardiac troponin T in adults with repaired tetralogy of Fallot , The 49th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery, Japan, July 11 - 13, 2013.
Lai C.T.M., Ng E.K., Chow P.C., Kwong A. and Cheung Y.F., Circulating microRNA expression profile and systemic right ventricular function in adults after atrial switch operation for complete transposition of the great arteries, BMC Cardiovasc Disord . 2013, 13: 73 doi:10.1186/1471-2261-13-73.
Li S.N., Yu W., Lai C.T.M., Wong S.J. and Cheung Y.F., Left ventricular mechanics in repaired tetralogy of Fallot with and without pulmonary valve replacement: analysis by three-dimensional speckle tracking echocardiography, PLoS One . 2013, 8: e78826 doi:10.1371/journal.pone.0078826.


Researcher : LEUNG YY

List of Research Outputs

Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Combination of Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, In: Hui KF, Leung YY, Yeung PL, Chiang AKS, EBV 50th Anniversary. 2014.
Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, Hong Kong College of Paediatricians, Annual Scientific Meeting. 2013.
LEUNG Y.Y., HUI K.F. and Chiang A.K.S., Effects of histone deacetylase inhibitor and proteasome inhibitor on Epstein-Barr Virus-Positive burkitt cells and lymphoblastoid cell lines, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 19.


Researcher : LI WYV

List of Research Outputs

Cheung Y.F., Lam W.W.M., Ip J.J.K., Cheng F.W.T., Yang J.Y.K., Yau J.P.W., Ho K.K.H., Li C.K., Li R.C.H., Yuen H.L., Ling A.S.C., LI W.Y.V. and Chan G.C.F., Cardiac magnetic resonance assessment of myocardial iron load and fibrosis in adult survivors of childhood leukaemias, Pediatric Academic Societies and Asian Society for Pediatric Research Joint Meeting 2014, Vancouver, Canada. 2014.
LI W.Y.V. and Cheung Y.F., Right ventricular mechanics in adolescents and young adults late after repair of coarctation of the aorta, 63rd Annual Scientific Session & Expo, Washington, USA. 2014.


Researcher : LING MT

List of Research Outputs

HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.


Researcher : LIU H

List of Research Outputs

LIU H. and Chan S.Y., ChIP-seq Analysis of Histone 3 Lysine 27 Trimethylation (H3K27me3) in Tspyl2 Mutant Mouse Primary Neurons, 18th Research Postgraduate Symposium, the University of Hong Kong (Hong Kong), 11-12 December 2013.
SO J., LIU H. and Chan S.Y., Comparison between the Functions of Testis-Specific Protein Y-linked-Like 1 (TSPYL1) and TSPYL2, 18th Research Postgraduate Symposium, the University of Hong Kong (Hong Kong), 11-12 December 2013.
TSANG K.H., Lai S.K., Li Q., Yung W.H., LIU H., Mak H.S., NG C.P., McAlonan G.M., Chan Y.S. and Chan S.Y., The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B, Scientific Reports. 2014, 4: 3654.


Researcher : Lai CTM

List of Research Outputs

LAI C.T.M. and Cheung Y.F., Determinants of plasma levels of high sensitivity cardiac troponin T in adults with repaired tetralogy of Fallot , The 49th Annual Meeting of Japanese Society of Pediatric Cardiology and Cardiac Surgery, Japan, July 11 - 13, 2013.
Lai C.T.M., Ng E.K., Chow P.C., Kwong A. and Cheung Y.F., Circulating microRNA expression profile and systemic right ventricular function in adults after atrial switch operation for complete transposition of the great arteries, BMC Cardiovasc Disord . 2013, 13: 73 doi:10.1186/1471-2261-13-73.
Li S.N., Yu W., Lai C.T.M., Wong S.J. and Cheung Y.F., Left ventricular mechanics in repaired tetralogy of Fallot with and without pulmonary valve replacement: analysis by three-dimensional speckle tracking echocardiography, PLoS One . 2013, 8: e78826 doi:10.1371/journal.pone.0078826.


Researcher : Lam IWT

List of Research Outputs

Wang L., Lam I.W.T., Ling W.L. and Li C.B., The role of c-Myc in methicillin-resistant staphylococcus aureus induced cytokines production., Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.


Researcher : Lam KT

List of Research Outputs

Chan P.L., Zheng J., Liu Y., Lam K.T., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One . 2013.
HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


Researcher : Lau ASY

Project Title:Cytokines, Signaling & Diseases 2003 The Role of Protein Kinase PKR in the Induction of Cytokine Expression by Bacillus Calmette Guerin Through NF-kappaB
Investigator(s):Lau ASY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2003


Project Title:Cytokine Dysregulation and Virus-Induced Cell Death in Avian Influenza Virus Infections
Investigator(s):Lau ASY, Peiris JSM
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:11/2005


Project Title:Factors affecting mycobacteria evasion of immunity: effects of HIV on cellular signaling and kinases
Investigator(s):Lau ASY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:09/2009


List of Research Outputs

Au K.Y., Li C.B. and Lau A.S.Y., Micro-RNAs mediated-regulation of mycobacteria-induced cytokines production, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.
El-Nezamy H.S., Tam P.K.H., Chen Y., Lau A.S.Y., Leung F.C.C., Chen S.F., Lan C.L.L. and Leung F.C.C., Impact of melamine-tainted milk of foetal kidneys and disease development later in life, Hong Kong Medical Journal. 2013, 19(supplement 8): S34-38.
LI H., Seneviratne C.J., Lau A.S.Y., Wang C.Y. and Jin L., Oral commensals and pathogens enhance hBD-2 expression in HOKs, Journal of Dental Research. 2013, 92 (Spec Iss B): 14 (APR).
Leon Y.Y., Yim H.C.H., Li C.B. and Lau A.S.Y., The role of MXD1 in influenza infection, Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.
Ling W.L., Wang L., Pong C.H., Lau A.S.Y. and Li C.B., A ROLE OF INTERLEUKIN-17A IN MODULATING INTRACELLULAR SURVIVAL OF MYCOBACTERIUM BOVIS BCG IN MURINE MACROPHAGES. , The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Pong C.H., Li C.B., Yim H.C.H. and Lau A.S.Y., Regulation of HIV-Tat induction of cytokine expression and consequent opportunistic infection by the proto-oncogene c-Myc, The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Sun W., Yang L.H., Lau A.S.Y. and Li C.B., Inhibitory Effect of Panax Notoginseng (PNG) Extracts on the TNF-α-induced MMP-9 Activity in Cardiomyoblasts, 17th International Congress "PHYTOPHARM 2013". 2013.
Wang L., Ling W.L., Lau A.S.Y. and Li C.B., The role of c-Myc in myocbateria-induced autophagy in human macrophages, Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.
Wang L., Ling W.L., Li C.B. and Lau A.S.Y., The role of c-Myc in phagocytosis of mycobacterial in human macrophages., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Wang L., Ling W.L., Lau A.S.Y. and Li C.B., The role of oncogene in mycobacteria-induced autophagy in human macrophages, The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Yang L.H., Law H.Y., Or C.T., Au K.Y., Li C.B. and Lau A.S.Y., Identification of an anti-viral compound with inhibitory effects on influenza replication, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.


Researcher : Lau WS

List of Research Outputs

Ip P., Li L., Rao N., Ng S...S...N., Lau W.S. and Chow C.B., Validation study of the Chinese Early Development Instrument (CEDI), BMC Pediatrics. London, BioMed Central, 2013, 13:146.


Researcher : Lau YL

Project Title:A community-based educational program on thalassaemias to enhance awareness with the aim to reduce burden of thalassaemia related health problems in Hong Kong
Investigator(s):Lau YL, Ha SY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Health Promotion Projects
Start Date:09/1997


Project Title:Comparison of process upgrade varicella vaccine (Puvv) with VARILRIX-TM
Investigator(s):Lau YL
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Other Funding Scheme
Start Date:07/1999


Project Title:p21 gene polymorphism with systemic lupus erythematosus and rheumatoid arthritis
Investigator(s):Lau YL, Lau WCS
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:Association of cytokine and chemokine genes polymorphism with susceptibility to SARS and severity of SARS
Investigator(s):Lau YL, Peiris JSM
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:09/2005


Project Title:Identification of coding variants associated with early-onset and familial systemic lupus erythematosus through whole exome sequencing and replication
Investigator(s):Lau YL, Sham PC, Yang W
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2011


Project Title:The effects of BTK mutation on TLR3-mediated type I IFN response against poliovirus infection in X-linked agammaglobulinemia
Investigator(s):Lau YL, Tu W, Lee PPW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


List of Research Outputs

Chan P.L., Zheng J., Liu Y., Lam K.T., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One . 2013.
Chan P.L., Zheng J., Liu Y., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One. 2013.
Chan P.Y.T., Ho M.H.K., Cheuk K.L.D., Lee T.L., Ha S.Y. and Lau Y.L., Unrelated cord blood transplantation in a pair of siblings with X-linked severe combined immunodeficiency: the case for early diagnosis and transplant, Hong Kong Journal of Paeditrics. 2014, 19: 32-36.
HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Lau Y.L. and Tu W., Case-control study of Sichuan and Hong Kong children with melamine-associated renal stones: renal ultrasonography and urinary IL-8 and MCP-1 levels, Hong Kong Medical Journal. 2013, 19(suppl 8): 26-30.
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L., Chan J.F.W., Woo P.C.Y., Tu W. and Lau Y.L., Penicillium marneffei infection and impaired IFN-γ immunity in humans with autosomal-dominant gain-of-phosphorylation STAT1 mutations, Journal of Allergy and Clinical Immunology. 2013.
Li S.L., Lau Y.L., Lam T.H., Yip P.S.F., Fan S.Y.S. and Ip P., HPV vaccination in Hong Kong: Uptake and reasons for non-vaccination amongst Chinese adolescent girls, Vaccine. 2013, 31: 5785-5788.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Mao H., Yen H., Liu Y., Lau Y.L., Peiris J.S.M. and Tu W., Conservation of T cell epitopes between seasonal influenza viruses and the novel influenza A H7N9 virus, Virologica Sinica. 2014, 29(3): 170-5.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.
Sattler S., Ling G.S., Xu D., Hussaarts L., Romaine A., Zhao H.Z., Fossati-Jimack L., Malik T., Cook H.T., Botto M., Lau Y.L., Smits H.H., Liew F.Y. and Huang F., IL-10-producing regulatory B cells induced by IL-33 (BregIL-33) effectively attenuate mucosal inflammatory responses in the gut, In: M.E. Gershwin, Journal of Autoimmunity. Elsevier, 2014, 50: 107-122.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
Tao Q.V., She W., Chu W.Y., Tso W.Y.W., Chan K.Y., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 23.
Tu W., yang H., luo H., mao M. and Lau Y.L., One-year follow up of melamine-associated renal stones in Sichuan and Hong Kong, Hong Kong Journal of Paediatrics. 2013.
Wu J.T.K., Leung S.M., Perera R.A.P.M., Chu K.W., Lee C.K., Hung I.F.N., Lin C.K., Lo S.V., Lau Y.L., Leung G.M., Cowling B.J. and Peiris J.S.M., Inferring influenza infection attack rate from seroprevalence data (abstract & poster presentation), Hong Kong College of Community Medicine Annual Scientific Meeting, 28 September 2013, Hong Kong. Hong Kong, HKCCM, 2013.
YEUNG K.S., Choufani S., Chen Y.A., Grafodatskaya D., Lee P.P.W., Yang W., Weksberg R., Lau Y.L. and Chung B.H.Y., Genome-wide DNA Methylation Analysis of Hong Kong Chinese Systemic Lupus Erythematosus Patients identified Hypomethylated Genes Related to Type I Interferon, Epigenomics of Common Diseases, Wellcome Trust Conference Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK, 7-10 November 2013.
Yang J., Lee P.P.W., Ying D., Ho M.H.K., Lee T.L., Yang W. and Lau Y.L., Molecular diagnosis for paediatric genetic disorders using whole exome sequencing of the next generation sequencing technology, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 17.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.
Zeng S., Yang J., Chung B.H.Y., Lau Y.L. and Yang W., EFIN: predicting the functional impact of nonsynonymous single nucleotide polymorphisms in human genome, BMC Genomics. 2014, 15: 455-463.
Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


Researcher : Law HY

List of Research Outputs

Yang L.H., Law H.Y., Or C.T., Au K.Y., Li C.B. and Lau A.S.Y., Identification of an anti-viral compound with inhibitory effects on influenza replication, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.


Researcher : Lee PPW

Project Title:Activation of autophagy limits IL-1beta production in monocytes expressing gain-of-function NLRP3 mutations
Investigator(s):Lee PPW, Lau YL
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:04/2014


List of Research Outputs

Chiu S.Y., Chan H.Y., Cheuk K.L.D., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Shum S.K., Treatment of children with drug-resistant graft-versus-host-disease by extracorporeal photopheresis, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 78.
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L., Chan J.F.W., Woo P.C.Y., Tu W. and Lau Y.L., Penicillium marneffei infection and impaired IFN-γ immunity in humans with autosomal-dominant gain-of-phosphorylation STAT1 mutations, Journal of Allergy and Clinical Immunology. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.
YEUNG K.S., Choufani S., Chen Y.A., Grafodatskaya D., Lee P.P.W., Yang W., Weksberg R., Lau Y.L. and Chung B.H.Y., Genome-wide DNA Methylation Analysis of Hong Kong Chinese Systemic Lupus Erythematosus Patients identified Hypomethylated Genes Related to Type I Interferon, Epigenomics of Common Diseases, Wellcome Trust Conference Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK, 7-10 November 2013.
Yang J., Lee P.P.W., Ying D., Ho M.H.K., Lee T.L., Yang W. and Lau Y.L., Molecular diagnosis for paediatric genetic disorders using whole exome sequencing of the next generation sequencing technology, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 17.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Lee SL

List of Research Outputs

Chau C.S.K., Lee S.L., Peiris J.S.M., Chan K.H., Chan E., Wong W.H.S. and Chiu S.S.S., Adenovirus respiratory infection in hospitalized children in Hong Kong: serotype-clinical syndrome association and risk factors for lower respiratory tract infection., Eur J Pediatr. 2013.


Researcher : Lee TL

List of Research Outputs

Chan P.Y.T., Ho M.H.K., Cheuk K.L.D., Lee T.L., Ha S.Y. and Lau Y.L., Unrelated cord blood transplantation in a pair of siblings with X-linked severe combined immunodeficiency: the case for early diagnosis and transplant, Hong Kong Journal of Paeditrics. 2014, 19: 32-36.
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L., Chan J.F.W., Woo P.C.Y., Tu W. and Lau Y.L., Penicillium marneffei infection and impaired IFN-γ immunity in humans with autosomal-dominant gain-of-phosphorylation STAT1 mutations, Journal of Allergy and Clinical Immunology. 2013.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.
Yang J., Lee P.P.W., Ying D., Ho M.H.K., Lee T.L., Yang W. and Lau Y.L., Molecular diagnosis for paediatric genetic disorders using whole exome sequencing of the next generation sequencing technology, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 17.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Leon YY

List of Research Outputs

Leon Y.Y., Yim H.C.H., Li C.B. and Lau A.S.Y., The role of MXD1 in influenza infection, Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.


Researcher : Li CB

Project Title:A role for oncogenes in the regulation of immune response to Mycobacterial infection
Investigator(s):Li CB
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2010


Project Title:Cellular Oncogene Dysregulation of Chemokine and Cytokine Expression in Influenza Virus Infection
Investigator(s):Li CB, Leon YY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:09/2011


Project Title:A role for proto-oncogene c-Myc in antibiotics-sensitive and -resistant bacteria-induced immune responses: a potential building block for the new treatment development
Investigator(s):Li CB
Department:LKS Medical Faculty
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:12/2011


Project Title:The role of c-Myc in anti-mycobaterial responses: from bacterial killing to T cell activation
Investigator(s):Li CB, Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:02/2014


Project Title:The effects of Coriolus Versicolor on TGF-beta induced tumor cell migration
Investigator(s):Li CB
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Au K.Y., Li C.B. and Lau A.S.Y., Micro-RNAs mediated-regulation of mycobacteria-induced cytokines production, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.
Leon Y.Y., Yim H.C.H., Li C.B. and Lau A.S.Y., The role of MXD1 in influenza infection, Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.
Ling W.L., Wang L., Pong C.H., Lau A.S.Y. and Li C.B., A ROLE OF INTERLEUKIN-17A IN MODULATING INTRACELLULAR SURVIVAL OF MYCOBACTERIUM BOVIS BCG IN MURINE MACROPHAGES. , The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Ling W.L., Wang L., Pong C.H., Chan G.C.F. and Li C.B., Investigating the role of inteleukin-17A on cytokines production by macrophages in response to bacterial infections., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Pong C.H., Chan G.C.F. and Li C.B., HIV-1 Tat dysregulation of KSHV induced immune response through the production of IL-8., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Pong C.H., Li C.B., Yim H.C.H. and Lau A.S.Y., Regulation of HIV-Tat induction of cytokine expression and consequent opportunistic infection by the proto-oncogene c-Myc, The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Sun W., Yang L.H., Lau A.S.Y. and Li C.B., Inhibitory Effect of Panax Notoginseng (PNG) Extracts on the TNF-α-induced MMP-9 Activity in Cardiomyoblasts, 17th International Congress "PHYTOPHARM 2013". 2013.
Wang L., Lam I.W.T., Ling W.L. and Li C.B., The role of c-Myc in methicillin-resistant staphylococcus aureus induced cytokines production., Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.
Wang L., Ling W.L., Lau A.S.Y. and Li C.B., The role of c-Myc in myocbateria-induced autophagy in human macrophages, Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.
Wang L., Ling W.L., Li C.B. and Lau A.S.Y., The role of c-Myc in phagocytosis of mycobacterial in human macrophages., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Wang L., Ling W.L., Lau A.S.Y. and Li C.B., The role of oncogene in mycobacteria-induced autophagy in human macrophages, The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Yang L.H., Law H.Y., Or C.T., Au K.Y., Li C.B. and Lau A.S.Y., Identification of an anti-viral compound with inhibitory effects on influenza replication, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.


Researcher : Li CH

List of Research Outputs

Lee V., Luk C.W., Cheuk K.L.D., Li C.H., Ling S.C., Leung A.W.K., Yuen H.L., Chiang A.K.S. and Shing M.M.K., Long term treatment outcome of conventional high grade osteosarcoma in Hong Kong children and adolescents – from the Hong Kong paediatric haematology and oncology study group, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Li CK

List of Research Outputs

Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.S.W., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Brain tumors of children <18-month-old: A population based study, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.W.S., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Uncommon types of brain tumors among Chinese children, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Li H

List of Research Outputs

Chiang A.K.S., Ha S.Y., Xiong H., Cheuk K.L.D., Li H. and Chan G.C.F., Outcome of hematopoietic stem cell transplantation in refractory / relapsed infant leukemia, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Li L

List of Research Outputs

Ip P., Li L., Rao N., Ng S...S...N., Lau W.S. and Chow C.B., Validation study of the Chinese Early Development Instrument (CEDI), BMC Pediatrics. London, BioMed Central, 2013, 13:146.


Researcher : Li S

List of Research Outputs

Li S., Wong S.J. and Cheung Y.F., Atrial an ventricular mechanics in patients after Fontan-type procedures: atriopulmonary connection versus extracardiac conduit, 63rd Annual Scientific Session & Expo, Washington, USA. 2014.


Researcher : Ling MT

List of Research Outputs

HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.


Researcher : Ling SC

List of Research Outputs

Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.S.W., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Brain tumors of children <18-month-old: A population based study, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.W.S., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Uncommon types of brain tumors among Chinese children, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Yuen A.N.Y., Ho S.M.Y., Chan C.K.Y., Lee V., Yuen H.L. and Ling S.C., The relationship between hope, rumination response styles, rumination content and psychological adjustment among childhood cancer patients and survivors, 45th Congress of the International Society of Paediatric Oncology. 2013.
Lee V., Luk C.W., Cheuk K.L.D., Li C.H., Ling S.C., Leung A.W.K., Yuen H.L., Chiang A.K.S. and Shing M.M.K., Long term treatment outcome of conventional high grade osteosarcoma in Hong Kong children and adolescents – from the Hong Kong paediatric haematology and oncology study group, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Ling WL

List of Research Outputs

Ling W.L., Wang L., Pong C.H., Lau A.S.Y. and Li C.B., A ROLE OF INTERLEUKIN-17A IN MODULATING INTRACELLULAR SURVIVAL OF MYCOBACTERIUM BOVIS BCG IN MURINE MACROPHAGES. , The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Ling W.L., Wang L., Pong C.H., Chan G.C.F. and Li C.B., Investigating the role of inteleukin-17A on cytokines production by macrophages in response to bacterial infections., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Wang L., Lam I.W.T., Ling W.L. and Li C.B., The role of c-Myc in methicillin-resistant staphylococcus aureus induced cytokines production., Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.
Wang L., Ling W.L., Lau A.S.Y. and Li C.B., The role of c-Myc in myocbateria-induced autophagy in human macrophages, Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.
Wang L., Ling W.L., Li C.B. and Lau A.S.Y., The role of c-Myc in phagocytosis of mycobacterial in human macrophages., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Wang L., Ling W.L., Lau A.S.Y. and Li C.B., The role of oncogene in mycobacteria-induced autophagy in human macrophages, The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.


Researcher : Liu APY

Project Title:Language and Communication in Genetic Counseling for Sudden Arrhythmia Death Syndromes (SADS) in Hong Kong: An Exploratory Study
Investigator(s):Liu APY, Chung BHY, Chau AKT, Yung TC, Zayts OA
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:01/2012
Completion Date:12/2013


Project Title:Copy-number variations in Chinese patients with conotruncal defects
Investigator(s):Liu APY, Wong WL, Chung BHY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:Immunogenicity and immunomodulatory activitiy of induced pluripotent stem cells-derived cardiomyocytes from human mesenchymal stem cells
Investigator(s):Liu APY, Poon NYE, Boheler KR, Chan GCF
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Leung W.Y., Liu A.P.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2013, 18: 182.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K. and Chan G.C.F., Central Nervous System Tumors In Children Under The Age Of Three: A Population Study By The Hong Kong Paediatric Haematology/oncology Study Group, Joint Annual Scientific Meeting 2014 of the Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd . 2014.
Liu A.P.Y., Sing M.M.K., Yuen H.L., Li C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K. and Chan G.C.F., Central Nervous System Tumors in Chinese Children Under The Age of 3, Journal of Pediatric Hematology/Oncology. 2014, 1.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K. and Chan G.C.F., Central nervous system tumors in Chinese children under the age of three: a population study by the Hong Kong Paediatric Haematology/Oncology Study Group, 16th International Symposium on Pediatric Neuro-Oncology, ISPNO 2014.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li R.C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K., Kwong D.L.W. and Chan G.C.F., Timing Of Adjuvant Radiotherapy And Treatment Outcome In Childhood Ependymoma, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li R.C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K., Kwong D.L.W. and Chan G.C.F., Timing of adjuvant radiotherapy and treatment outcome in childhood ependymoma, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 53.
Liu A.P.Y., Shing M.M.K., Yuen H.L., Li C.H., Ling S.C., Luk C.W., Ha S.Y., Li C.K., Kwong D.L.W. and Chan G.C.F., Timing of adjuvant radiotherapy and treatment outcome in childhood ependymoma, Pediatric Blood & Cancer. 2014, 61: 606-611.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Liu A.P.Y., Yung T.C., Chau A.K.T. and Chung B.H.Y., Unveiling the genetics of long QT syndrome: A local paediatric experience, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 20.
Liu A.P.Y., Yung T.C., Chau A.K.T. and Chung B.H.Y., Unveiling the genetics of long QT syndrome: a local paediatric experience, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
She W.M.K., Liu A.P.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). Medcom Limited, 2013, 18: 266-267.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.


Researcher : Liu Y

List of Research Outputs

Chan P.L., Zheng J., Liu Y., Lam K.T., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One . 2013.
Chan P.L., Zheng J., Liu Y., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One. 2013.
HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Mao H., Yen H., Liu Y., Lau Y.L., Peiris J.S.M. and Tu W., Conservation of T cell epitopes between seasonal influenza viruses and the novel influenza A H7N9 virus, Virologica Sinica. 2014, 29(3): 170-5.
Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


Researcher : Liu Y

List of Research Outputs

Chan P.L., Zheng J., Liu Y., Lam K.T., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One . 2013.
Chan P.L., Zheng J., Liu Y., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One. 2013.
HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Mao H., Yen H., Liu Y., Lau Y.L., Peiris J.S.M. and Tu W., Conservation of T cell epitopes between seasonal influenza viruses and the novel influenza A H7N9 virus, Virologica Sinica. 2014, 29(3): 170-5.
Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


Researcher : Low LCK

Project Title:12th Asia Pacific Congress of Paediatrics and 2nd Asia Pacific Congress of Paediatric Nursing The Role of Nutritional Intake and Total Energy Expenditure on Early Growth of Babies Born with Intrauterine Growth Retardation
Investigator(s):Low LCK
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2006




Researcher : Luk CW

List of Research Outputs

Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.S.W., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Brain tumors of children <18-month-old: A population based study, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.W.S., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Uncommon types of brain tumors among Chinese children, 45th Congress of the International Society of Paediatric Oncology. 2013.
Lee V., Luk C.W., Cheuk K.L.D., Li C.H., Ling S.C., Leung A.W.K., Yuen H.L., Chiang A.K.S. and Shing M.M.K., Long term treatment outcome of conventional high grade osteosarcoma in Hong Kong children and adolescents – from the Hong Kong paediatric haematology and oncology study group, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Luk HM

List of Research Outputs

YEUNG K.S., Chee W.Y.Y., Luk H.M., Tang M.H.Y., Lau E.T.K., Shuen Y.A., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Evidence of spread of X chromosome inactivation on chromosome 15 in a girl with an unbalanced t(X;15) transolcation, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 64.


Researcher : Mak HS

List of Research Outputs

CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., Enriched housing condition reduces stressful behavior in Lrrc7 mutant mice, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong, 12-14 June 2014.
TSANG K.H., Lai S.K., Li Q., Yung W.H., LIU H., Mak H.S., NG C.P., McAlonan G.M., Chan Y.S. and Chan S.Y., The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B, Scientific Reports. 2014, 4: 3654.


Researcher : Mao H

List of Research Outputs

HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L., Chan J.F.W., Woo P.C.Y., Tu W. and Lau Y.L., Penicillium marneffei infection and impaired IFN-γ immunity in humans with autosomal-dominant gain-of-phosphorylation STAT1 mutations, Journal of Allergy and Clinical Immunology. 2013.
Mao H., Yen H., Liu Y., Lau Y.L., Peiris J.S.M. and Tu W., Conservation of T cell epitopes between seasonal influenza viruses and the novel influenza A H7N9 virus, Virologica Sinica. 2014, 29(3): 170-5.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.


Researcher : Mok TKG

List of Research Outputs

Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Mok T.K.G., Chu W.Y., Tan T.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(2): 129.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.


Researcher : NG CP

List of Research Outputs

CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., Enriched housing condition reduces stressful behavior in Lrrc7 mutant mice, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong, 12-14 June 2014.
NG C.P., Li Q. and Chan S.Y., The Role of Densin180 in Anxiety Behavior and Protein Distribution, 18th Research Postgraduate Symposium, the University of Hong Kong (Hong Kong), 11-12 December 2013.
TSANG K.H., Lai S.K., Li Q., Yung W.H., LIU H., Mak H.S., NG C.P., McAlonan G.M., Chan Y.S. and Chan S.Y., The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B, Scientific Reports. 2014, 4: 3654.


Researcher : NI K

List of Research Outputs

Xia Q., Zhou L., Peng C., Hao R., NI K., Zang N., Ren L., Deng Y., Xie X., He L., Tian D., Wang L., Huang A., Zhao Y., Zhao X., Fu Z., Tu W. and Liu E., Detection of respiratory syncytial virus fusion protein variants between 2009 and 2012 in China, Archives of Virology. 2013.


Researcher : NING J

List of Research Outputs

NING J., Chan K.H. and Chiang A.K.S., Development of immunodominance hierarchies concurrent with enhanced polyfunctionality in T cell immunity towards Epstein - Barr virus, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2013. 60.


Researcher : Or CT

List of Research Outputs

Yang L.H., Law H.Y., Or C.T., Au K.Y., Li C.B. and Lau A.S.Y., Identification of an anti-viral compound with inhibitory effects on influenza replication, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.


Researcher : Pong CH

List of Research Outputs

Ling W.L., Wang L., Pong C.H., Lau A.S.Y. and Li C.B., A ROLE OF INTERLEUKIN-17A IN MODULATING INTRACELLULAR SURVIVAL OF MYCOBACTERIUM BOVIS BCG IN MURINE MACROPHAGES. , The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.
Ling W.L., Wang L., Pong C.H., Chan G.C.F. and Li C.B., Investigating the role of inteleukin-17A on cytokines production by macrophages in response to bacterial infections., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Pong C.H., Chan G.C.F. and Li C.B., HIV-1 Tat dysregulation of KSHV induced immune response through the production of IL-8., The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2014.
Pong C.H., Li C.B., Yim H.C.H. and Lau A.S.Y., Regulation of HIV-Tat induction of cytokine expression and consequent opportunistic infection by the proto-oncogene c-Myc, The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.


Researcher : Poon WKG

List of Research Outputs

Lee H.H.C., Mak C.M., Poon W.K.G., Wong K.Y. and Lam C.W., Cost-benefit analysis of Hyperphenylalaninemia Due to 6-Pyruvoyl-Tetrahydropterin Synthase (PTPS) Deficiency: For Consideration of Expanded Newborn Screening in Hong Kong, In: Lee HH, Mak CM, Poon GW, Wong KY, Lam CW, J Med Screen. 2014.


Researcher : QIN G

List of Research Outputs

Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


Researcher : ROBLES JD

List of Research Outputs

LAU K.S., WONG T.W., Ho K.Y., TANG Y.H., ROBLES J.D., WEI X., CHAN C.S., TANG H.L., Lam E.Y.M., Wong K.K.Y., Chan G.C.F., Shum H.C. and Tsia K.K.M., Ultrafast high-contrast microfluidic cellular imaging by asymmetric-detection time-stretch optical microscopy (ATOM), 2013 Frontiers in Optics/Laser Science XXIX (FiO/LS). 2013.
WONG T.W., Lau K.S.A., Ho K.Y.K., Tang M.Y.H., ROBLES J.D., WEI X., CHAN C.S., TANG H.L., Lam E.Y.M., Wong K.K.Y., Chan G.C.F., Shum H.C. and Tsia K.K.M., Asymmetric-detection time-stretch optical microscopy (ATOM) for ultrafast high-contrast cellular imaging in flow, Scientific Reports. 2014, 4: 3656.


Researcher : SO J

List of Research Outputs

SO J., LIU H. and Chan S.Y., Comparison between the Functions of Testis-Specific Protein Y-linked-Like 1 (TSPYL1) and TSPYL2, 18th Research Postgraduate Symposium, the University of Hong Kong (Hong Kong), 11-12 December 2013.


Researcher : Shuen YA

List of Research Outputs

YEUNG K.S., Chee W.Y.Y., Luk H.M., Tang M.H.Y., Lau E.T.K., Shuen Y.A., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Evidence of spread of X chromosome inactivation on chromosome 15 in a girl with an unbalanced t(X;15) transolcation, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 64.


Researcher : So LY

List of Research Outputs

Chiu S.S.S., Lo J.Y.C., Chan K.H., Chan L.Y., So L.Y., Wu P., Cowling B.J., Chen H.S.R. and Peiris J.S.M., Population-Based Hospitalization Burden of Influenza A Virus Subtypes and Antigenic Drift Variants in Children in Hong Kong (2004-2011), PLOS One. 2014, 9(4): e92914.


Researcher : TSANG KH

List of Research Outputs

TSANG K.H., Lai S.K., Li Q., Yung W.H., LIU H., Mak H.S., NG C.P., McAlonan G.M., Chan Y.S. and Chan S.Y., The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B, Scientific Reports. 2014, 4: 3654.


Researcher : Tan TY

List of Research Outputs

Chung B.H.Y. and Tan T.Y., Similarities and Differences in Medical Genetic Practice in Asia and Australasia: Cross-Cultural Genetic Counselling Experiences in Hong Kong, China, HGSA (Human Genetics Society of Australasia), Queenstown, New Zealand, 4-7 August 2013.
Mok T.K.G., Chu W.Y., Tan T.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(2): 129.


Researcher : Tao QV

List of Research Outputs

Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
Tao Q.V., She W., Chu W.Y., Tso W.Y.W., Chan K.Y., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 23.


Researcher : Tsang AMC

List of Research Outputs

Sobowale K., Zhou N., Van Voorhees B.W., Stewart S., Tsang A.M.C., Ip P., Fabrizio C., Wong K.L. and Chim D., Adaptation of an internet-based depression prevention intervention for Chinese adolescents: from "CATCH-IT" to "grasp the opportunity", Internationl Journal of Adolescent Medicine and Health . 2013, 25: 127-137.


Researcher : Tso WWY

Project Title:Genetic basis of autism and macrocephaly
Investigator(s):Tso WYW, Wong VCN, Fung CW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012


List of Research Outputs



Researcher : Tso WYW

Project Title:Genetic basis of autism and macrocephaly
Investigator(s):Tso WYW, Wong VCN, Fung CW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012


List of Research Outputs

Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
Tao Q.V., She W., Chu W.Y., Tso W.Y.W., Chan K.Y., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 23.
Tso W.Y.W., Yung A.W.Y., Lau H.Y. and Chan G.C.F., Basal ganglia germinoma: MRI classifications correlates well with neurological and cognitive outcome, Journal of Paediatric Haematology & Oncology. 2013, 36(7): e443-e447.
Tso W.Y.W., Kwong A.K., Fung C.W. and Wong V.C.N., Folinic acid responsive epilepsy in Ohtahara Syndrome caused by STXBP1 mutation, Pediatric Neurology. 2014, 50(2): 177-180.
Tso W.Y.W., Wong V.C.N., Ao L.J., Li M., Zhang X., Jiao F.Y., Xu X., Du K.X., Farragher B., Xia X.L. and Challis D., Griffiths Mental Developmental Scales (GMDS): Validation for Chinese children, Annual Scientific Meeting, Hong Kong College of Paediatricians, Hong Kong, 7 December 2013. (Free paper Award). 2013.


Researcher : Tu W

Project Title:Humanized mouse as a model to study the antiviral activity of human gammadelta-T cells against human and avian influenza A viruses in vivo
Investigator(s):Tu W, Lau YL, Peiris JSM, Law HKW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:08/2007


Project Title:Antiviral Activity of Human gammadelta-T Cells against Epstein-Barr Virus Infection
Investigator(s):Tu W, Lau YL, Liu Y, Tsao GSW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:Immune Evasion of Natural Killer Cells for Influenza Virus in Vivo
Investigator(s):Tu W, Lau YL, Mao H, Liu Y
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:12/2011


Project Title:Induction of tolerance by alloantigen-specific regulatory T cells in humanized mice and non-human primates
Investigator(s):Tu W, Lau YL, Liu Y
Department:Paediatrics & Adolescent Med
Source(s) of Funding:NSFC/RGC Joint Research Scheme
Start Date:01/2012


Project Title:15th International Congress of Immunology; TLR5 signaling enhances the proliferation of human allogeneic CD40-activated-B-cell-induced regulatory CD4 T cells
Investigator(s):Tu W
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


Project Title:Role of human gammadelta-T cells in the generation of influenza virus-specific antibody
Investigator(s):Tu W, Lau YL, Liu Y
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


Project Title:Antiviral Activity of Human γδ-T cells against Enterovirus 71
Investigator(s):Tu W, Lau YL, Liu Y, Zheng J
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


Project Title:Interaction between human NK cells and other immune cells and its effects on the fate decision of NK cells during influenza virus infection.
Investigator(s):Tu W
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Chan P.L., Zheng J., Liu Y., Lam K.T., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One . 2013.
Chan P.L., Zheng J., Liu Y., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One. 2013.
Dou Y., Zhao Y., Zhang Z.Y., Mao H., Tu W. and Zhao X., Respiratory syncytial virus infection induces higher Toll-like receptor-3 expression and TNF-α production than human metapneumovirus infection, Plos One. 2013, 8(9): e73488.
HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Lau Y.L. and Tu W., Case-control study of Sichuan and Hong Kong children with melamine-associated renal stones: renal ultrasonography and urinary IL-8 and MCP-1 levels, Hong Kong Medical Journal. 2013, 19(suppl 8): 26-30.
Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L., Chan J.F.W., Woo P.C.Y., Tu W. and Lau Y.L., Penicillium marneffei infection and impaired IFN-γ immunity in humans with autosomal-dominant gain-of-phosphorylation STAT1 mutations, Journal of Allergy and Clinical Immunology. 2013.
Li J., Li H., Mo H., Mao M. and Tu W., Impaired NK cell antiviral cytokine response against influenza virus in small-for-gestational-age neonates, Cellular and Molecular Immunology. 2013.
Liu T., Zang N., Zhou N., Li W., Xie X., Deng Y., Li S., Luo R., Long X., Zhou L., Zhao X., Tu W., Wang L., Tan B. and Liu E., Resveratrol inhibits the TRIF dependent pathway by up-regulating SARM, contributing to anti-inflammatory effects after respiratory syncytial virus infection, Journal of Virology. 2014.
Mao H., Yen H., Liu Y., Lau Y.L., Peiris J.S.M. and Tu W., Conservation of T cell epitopes between seasonal influenza viruses and the novel influenza A H7N9 virus, Virologica Sinica. 2014, 29(3): 170-5.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.
Tu W., yang H., luo H., mao M. and Lau Y.L., One-year follow up of melamine-associated renal stones in Sichuan and Hong Kong, Hong Kong Journal of Paediatrics. 2013.
Xia Q., Zhou L., Peng C., Hao R., NI K., Zang N., Ren L., Deng Y., Xie X., He L., Tian D., Wang L., Huang A., Zhao Y., Zhao X., Fu Z., Tu W. and Liu E., Detection of respiratory syncytial virus fusion protein variants between 2009 and 2012 in China, Archives of Virology. 2013.
Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


Researcher : WONG PTY

List of Research Outputs

Wong V.C.N., Fung C.K.Y. and WONG P.T.Y., Use of Dysmorphology for Subgroup Classification on Autism Spectrum Disorder in Chinese Children. , Journal of autism and developmental disorders. . 2014, 44(1): 9-18.


Researcher : Wong KY

List of Research Outputs

Lee H.H.C., Mak C.M., Poon W.K.G., Wong K.Y. and Lam C.W., Cost-benefit analysis of Hyperphenylalaninemia Due to 6-Pyruvoyl-Tetrahydropterin Synthase (PTPS) Deficiency: For Consideration of Expanded Newborn Screening in Hong Kong, In: Lee HH, Mak CM, Poon GW, Wong KY, Lam CW, J Med Screen. 2014.


Researcher : Wong SJ

List of Research Outputs

Chen H.S.R., Wong S.J., Wong W.H.S. and Cheung Y.F., Arterial mechanics at rest and during exercise in adolescents and young adults after arterial switch operation for complete transposition of the great arteries , Amercian Journal of Cardiology. 2014, 113: 713-718.
Hou J., Yu H.K., Wong S.J. and Cheung Y.F., Atrial mechanics after surgical repair of tetralogy of Fallot, Echocardiography . 2014, 00: 1-9 (DOI:10.1111/echo.12611).
Li S., Wong S.J. and Cheung Y.F., Atrial an ventricular mechanics in patients after Fontan-type procedures: atriopulmonary connection versus extracardiac conduit, 63rd Annual Scientific Session & Expo, Washington, USA. 2014.
Li S.J., Wong S.J. and Cheung Y.F., Atrial and ventricular mechanics in patients after fontan-type procedures: atriopulmonary connection versus extracardiac conduit, Journal of American Society of Echocardiography. 2014, 2014: doi.org/10.1016/j.echo.2014.01.027.
Li S.J., Yu H.K., Wong S.J. and Cheung Y.F., Right and left ventricular mechanics and interaction late after ballon valvoplasty for pulmonary stenosis , European Heart Journal - Cardiovascular Imaging . 2014, doi:10.1093/ehjci/jeu058.
Li S.N., Yu W., Lai C.T.M., Wong S.J. and Cheung Y.F., Left ventricular mechanics in repaired tetralogy of Fallot with and without pulmonary valve replacement: analysis by three-dimensional speckle tracking echocardiography, PLoS One . 2013, 8: e78826 doi:10.1371/journal.pone.0078826.


Researcher : Wong VCN

Project Title:Rett Syndrome :Systematic screening of MECP2 in children with autistic traits and or unexplained mental retardation/ encephalopathy to define the spectrum of Rett Syndrome phenotypes resulting from mutations in MECP2
Investigator(s):Wong VCN
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:01/2006


Project Title:Genetic analysis of PCDH19 and TSPYL mutation in Chinese children with GEFS+ and Dravet Syndromeencephaolpathy
Investigator(s):Wong VCN, Kwong KY, Fung CW, Chan SY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:05/2012


Project Title:Mutation analysis of CDKL5, STXBP1 and GABA receptor subunit genes in Chinese children with infantile spasms (IS)
Investigator(s):Wong VCN, Kwong KY, Fung CW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:A study of copy number variations (CNVs) of genes NRXN1, GRIN2A, GRIN2B and PCDH19 associated with synaptic function in Chinese children with infantile epileptic encephalopathies
Investigator(s):Wong VCN, Kwong KY, Fung CW
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:05/2014


List of Research Outputs

Baum L., Haerin B.S., Ng H.K., Wong V.C.N., Ng P.W., Lui C.H.T., Sin N.C., Zhang C., Tomlinson B., Wong G.W.K., Tan H.J., Raymond A.A., Mohamed Z. and Kwan P., Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy, Human Genetics. 2014. Springer, 2013, 133: 651-659.
Bolte S., de Schipper E., Robison J.E., Wong V.C.N., Selb M., Singhal N., de Vries P.J. and Zwaigenbaum L., Classification of Functioning and Impairment: The Development of ICF Core Sets for Autism Spectrum Disorder, Autism Research. 2014, 7: 167-172.
Bonhoeffer J., Imoukhuede E.B., Aldrovandi G., Bachtiar N.S., Chan E.S., Chang S., Chen R.T., Fernandopulle R., Goldenthal K.L., Heffelfinger J.D., Hossain S., Jevaji I., Khamesipour A., Kochhar S., Makhene M., Malkin E., Nalin D., Prevots R., Ramasamy R., Sellers S., Vekemans J., Walker K.B., Wilson P., Wong V.C.N., Zaman K. and Heininger U., Template Protocol For Clinical Trials Investigating Vaccines—focus On Safety Elements, Vaccine. 2013, 31: 5602-620.
Chan S.H.S., Lo I.F.M., Cherk S., Cheng W.W.S., Fung E., Yeung W.L., Lee W.C., Wong S., Ma C.K.L., Tai S.M., Yau M.M., Ng G., Wu S.P. and Wong V.C.N., A territory wide study for dystrophinopathy in Hong Kong, 18th International congress of the World Muscle Society. October 1st to 6th 2013. (poster presentation) Neuromuscular Disorder. 2013;23(9- 10):776 [Abstract] . 2013, 23(9-10): 776.
Chan S.H.S., Lo I.F.M., Cherk S., Cheng W.W.S., Fung E., Yeung W.L., Lee W.C., Wong S., Ma C.K.L., Tai S.M., Yau M.M., Ng G., Wu S.P. and Wong V.C.N., A territory wide study for dystrophinopathy in Hong Kong, 18th International congress of the World Muscle Society, 1-6 October 2013 [Abstract in Neuromuscular Disord 2013;23(9-10):776. 2013.
Chan S.H.S., Chan K.Y., Yau E., Ng G., Wu S.P., Yau M., Fung E., Ngan M., Kwong L., Yau M.M., Ma K.M., Ma C.K., Liu K.T., Cherk S. and Wong V.C.N., Guillain Barre Syndrome (GBS) in children: Diagnosis, management and local case review, 13th Asian Oceanian Myology Meeting, Manila, The Philippines. 14-17 May 2014 (poster presentation). 2014.
Chan S.H.S., Chan K.Y., Yau E., Ng G., Wu S.P., Yau M., Fung E., Ngan M., Kwong L., Yau M.M., Ma K.M., Ma C.K., Liu K.T., Cherk S. and Wong V.C.N., Guillain Barre Syndrome (GBS) in children: Diagnosis, management and local case review, 13th Asian Oceanian Myology Meeting, Manila, Philippine, 14-17 May 2014.
Chan S.H.S., Tsang D.S.F., Wong V.C.N. and Chan G.C.F., Spinal primitive neuroectodermal tumour mimicking as chronic inflammatory demyelinating polyneuropathy - a case report and review of literatures [Epub ahead of print], Journal of Child Neurology. 2014.
Ho C.C.A., Kwong K.Y., Fung C.W. and Wong V.C.N., Clinical And Genetic Evaluation Of 23 Children With Infantile Onset Epileptic Encephalopathy (iee), The 3rd Hong Kong Neurological Congress Cum 26th Annual Scientific Meeting Of The Hong Kong Neurological Society. 2-3 November, 2013. (Free Paper award). 2013.
Ho C.C.A., Fung C.W., Siu T.S., Ma O.C.K., Lam C.W., Tam S. and Wong V.C.N., Lathosterolosis: A Disorder Of Cholesterol Biosynthesis Resembling Smith-lemli-opitz Syndrome, Journal Of Inherited Metabolic Disease . 2014, 12: 129-134.
Tso W.W.Y., Kwong K.Y., Wong V.C.N. and Fung C.W., Folinic acid responsive epilepsy in Ohtahara syndrome caused by STXBP1 mutation., Pediatric Neurology. 2014.. 2013, 50: 177-180.
Tso W.Y.W., Kwong A.K., Fung C.W. and Wong V.C.N., Folinic acid responsive epilepsy in Ohtahara Syndrome caused by STXBP1 mutation, Pediatric Neurology. 2014, 50(2): 177-180.
Tso W.Y.W., Wong V.C.N., Ao L.J., Li M., Zhang X., Jiao F.Y., Xu X., Du K.X., Farragher B., Xia X.L. and Challis D., Griffiths Mental Developmental Scales (GMDS): Validation for Chinese children, Annual Scientific Meeting, Hong Kong College of Paediatricians, Hong Kong, 7 December 2013. (Free paper Award). 2013.
Wong V.C.N., Accreditation of Subspecialty of Paediatrics Neurology (PN), (Program Director for QMH-DKCH) - 2013, The Hong Kong College of Paediatricians . 2013.
Wong V.C.N., Accreditation of the Subspecialty of Developmental Behavioural Paediatrics (DBP), (Program Director for DKCH) - 2013, The Hong Kong College of Paediatricians . 2013.
Wong V.C.N., Accreditation of the Subspecialty of Paediatrics Neurology (PN), (Chairman of Working Group for Paediatric Subspecialty Accreditation - Provisional Board of Paediatric Neurology) - 2013 , The Hong Kong College of Paediatricians . 2013.
Wong V.C.N., American Journal of Physical Medicine & Rehabilitation, 2014.
Wong V.C.N., Editorial Board Member (Since 2012), Evidence-Based Complementary and Alternative Medicine. 2014.
Wong V.C.N., Reviewer (Since 2000), Medical Progress. 2014.
Wong V.C.N., Reviewer (Since 2000), Pediatrics. 2014.
Wong V.C.N., Reviewer (Since 2010), Evidence Bases Complementary and Alternative Medicine. 2014.
Wong V.C.N., Fung C.K.Y. and WONG P.T.Y., Use of Dysmorphology for Subgroup Classification on Autism Spectrum Disorder in Chinese Children. , Journal of autism and developmental disorders. . 2014, 44(1): 9-18.


Researcher : Wong WHS

List of Research Outputs

Chan D.F.Y., Lau T., Wong W.H.S., Ip P., Kwong N.S. and Li C.K., Cluster evaluation on teenage pregnancy management in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 31.
Chau C.S.K., Lee S.L., Peiris J.S.M., Chan K.H., Chan E., Wong W.H.S. and Chiu S.S.S., Adenovirus respiratory infection in hospitalized children in Hong Kong: serotype-clinical syndrome association and risk factors for lower respiratory tract infection., Eur J Pediatr. 2013.
Chen H.S.R., Wong S.J., Wong W.H.S. and Cheung Y.F., Arterial mechanics at rest and during exercise in adolescents and young adults after arterial switch operation for complete transposition of the great arteries , Amercian Journal of Cardiology. 2014, 113: 713-718.
Chiu I.W.S., Chow C.B., Ip P., Ho K.W. and Wong W.H.S., Injuries among children 0 to 19 years in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 38.
Gale S.C., Ip P., Chow C.B., Wong W.H.S., Chung B.H.Y. and Ip D.K.M., An estimate of the prevalence of down's syndrome in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 42.
Gale S.C., Chu W.Y., Ip P., Chow C.B., Wong W.H.S., Ip D.K.M. and Chung B.H.Y., Factors influencing length of stay amongst people with down's syndrome, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 43.
Ho K.W., Chow C.B., Ip P., Leung M., Chow Y.H., Yeung A., Wong W.H.S. and Chiu I.W.S., Creating safe playgrounds: A safety promotion approach, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 45.
Ip P., Chan E.K.L., Chow C.B. and Wong W.H.S., Executive Summary of Epidemiology of Child Abuse and Its Geographic Distribution in Hong Kong: An Important Social Indicator of Different Districts and Communities (A Central Policy Unit Commissioned Report), 2013.
Ip P., Chan E.K.L., Chow C.B. and Wong W.H.S., Executive Summary of Epidemiology of Child Abuse and Its Geographic Distribution in Hong Kong: An Important Social Indicator of Different Districts and Communities (A Central Policy Unit Commissioned Report). Aug 2013, 2013.
Ip P., Lam T.H., Chan S.S.C., Ho K.W., Lo L.A., Chiu I.W.S., Wong W.H.S. and Chow C.B., Use of Internet viral marketing to promote smoke-free lifestyles among Chinese adolescents, PLoS One. 2014, 9: e99082.
Man K.C.K., Chan E.W., Douglas I., Ip P., Wong W.H.S., Coghill D. and Wong I.C.K., Attention-Deficit/Hyperactivity disorder (ADHD) Pharmacological Treatment and its Effect on Accident and Emergency Admission due to injury: a self-controlled case series study., 3rd EUNETHYDIS, Istanbul, Turkey, 21-24 May . 2014.
Mok W.K.Y., Wong W.H.S., Chu W.Y., Chung B.H.Y. and Ip P., Health-related quality of life of Chinese individuals with down syndrome in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 55.
Mok W.K.Y., Chu W.Y., Wong W.H.S., Ip P., Zayts O.A. and Chung B.H.Y., What should be said an what should not be said> - Perception of parents and caregivers of individuals with down syndrome in Hong Kong on sensitive language in Cantonese used in healthcare setting, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 39.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Wong WL

List of Research Outputs

Chu W.Y., Wong W.L. and Chung B.H.Y., What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(1): 41.
Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.


Researcher : XIANG Z

List of Research Outputs

Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


Researcher : YEUNG KS

List of Research Outputs

YEUNG K.S., Chee W.Y.Y., Luk H.M., Tang M.H.Y., Lau E.T.K., Shuen Y.A., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Evidence of spread of X chromosome inactivation on chromosome 15 in a girl with an unbalanced t(X;15) transolcation, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 64.
YEUNG K.S., Choufani S., Chen Y.A., Grafodatskaya D., Lee P.P.W., Yang W., Weksberg R., Lau Y.L. and Chung B.H.Y., Genome-wide DNA Methylation Analysis of Hong Kong Chinese Systemic Lupus Erythematosus Patients identified Hypomethylated Genes Related to Type I Interferon, Epigenomics of Common Diseases, Wellcome Trust Conference Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK, 7-10 November 2013.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 36.


Researcher : YEUNG PL

List of Research Outputs

Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Combination of Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, In: Hui KF, Leung YY, Yeung PL, Chiang AKS, EBV 50th Anniversary. 2014.
Hui K.F., LEUNG Y.Y., YEUNG P.L. and Chiang A.K.S., Suberoylanilide Hydroxamic Acid and Brotezomib Synergistically Induces Apoptosis of EBV-Positive Burkitt Lymphoma Cells of Wp-Restricted or Type III Latency, Hong Kong College of Paediatricians, Annual Scientific Meeting. 2013.


Researcher : Yang J

List of Research Outputs

Yang J., Lee P.P.W., Ying D., Ho M.H.K., Lee T.L., Yang W. and Lau Y.L., Molecular diagnosis for paediatric genetic disorders using whole exome sequencing of the next generation sequencing technology, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 17.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.
Zeng S., Yang J., Chung B.H.Y., Lau Y.L. and Yang W., EFIN: predicting the functional impact of nonsynonymous single nucleotide polymorphisms in human genome, BMC Genomics. 2014, 15: 455-463.


Researcher : Yang LH

Project Title:Discovery and Validation of antiviral small-molecule inhibitors for influenza virus replication
Investigator(s):Yang LH, Law HY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:02/2012


List of Research Outputs

Sun W., Yang L.H., Lau A.S.Y. and Li C.B., Inhibitory Effect of Panax Notoginseng (PNG) Extracts on the TNF-α-induced MMP-9 Activity in Cardiomyoblasts, 17th International Congress "PHYTOPHARM 2013". 2013.
Yang L.H., Law H.Y., Or C.T., Au K.Y., Li C.B. and Lau A.S.Y., Identification of an anti-viral compound with inhibitory effects on influenza replication, 11th Joint Meeting of the ICS and ISICR: Cytokines 2013.


Researcher : Yang M

Project Title:Protective effect of thrombopoietin on iron-induced cardiomyopathy
Investigator(s):Yang M
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Children's Thalassaemia Foundation - General Awards
Start Date:07/2007


Project Title:The effect of melatonin in the treatment of thrombocytopenia
Investigator(s):Yang M
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme
Start Date:01/2008


Project Title:The protective effects of thrombopoietin and amlodipine on iron overload-induced human mesenchymal stem cell damage: its impact on iron overload related osteopenia & osteoporosis
Investigator(s):Yang M, Chan GCF, Cheung YF, Liu C
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Children's Thalassaemia Foundation - General Awards
Start Date:01/2009




Researcher : Yang W

Project Title:Meta-Analysis of two Asian GWAS datasets for identification of novel genetic variants associated with systemic lupus erythematosus
Investigator(s):Yang W, Lau YL, Sham PC, Yang J
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:Gene-based meta-analysis and further replication of SLE susceptibility genes in Asians
Investigator(s):Yang W
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013
Completion Date:06/2014


Project Title:Annual meeting of American Society of Human Genetics; Massively parallel sequencing as a tool for HLA typing
Investigator(s):Yang W
Department:Paediatrics & Adolescent Med
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013


Project Title:Identifying susceptibility genes in the human MHC region independently associated with systemic lupus erythematosus (SLE) in Chinese populations
Investigator(s):Yang W, Lau YL, Sham PC
Department:Paediatrics & Adolescent Med
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Molecular diagnosis for severe combined immunodeficiencies (SCID) using whole exome sequencing
Investigator(s):Yang W, Lau YL, Lee PPW, Chung BHY, Yang J
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:02/2014


Project Title:Development of a database on genetic variants found by Whole Exome Sequencing to aid variant filtering and prioritization in genetic studies
Investigator(s):Yang W, Ying D, Yang J
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Lee P.P.W., Mao H., Yang W., Chan K.W., Ho M.H.K., Lee T.L., Chan J.F.W., Woo P.C.Y., Tu W. and Lau Y.L., Penicillium marneffei infection and impaired IFN-γ immunity in humans with autosomal-dominant gain-of-phosphorylation STAT1 mutations, Journal of Allergy and Clinical Immunology. 2013.
Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.
Lo I.F.M., Leung K.C., Luk H.M.M., Wong W.L., Tang L.Y.F., Chu Y.W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Chan Y.K. and Chung B.H.Y., Massive parallel sequencing for the genetic diagnosis of rasopathies – a study of 58 Chinese patients in Hong Kong. , Poster presentation in CCMG Annual Meeting, 2013.. 2013.
Mao H., Lee P.P.W., Yang W., Ling M.T., Chan K.W., Ho M.H.K., Lee T.L., Tu W. and Lau Y.L., Mycobacterial and candida infections in a patient with novel dominant negative mutation of STAT1 linker domain, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 20.
WANG P., Siu K.L., Zhang Y., Yang W., Kok K.H. and Jin D., Roles of a novel splice variant of human IFI16 in innate immune response, 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, June 14, 2014.
YEUNG K.S., Choufani S., Chen Y.A., Grafodatskaya D., Lee P.P.W., Yang W., Weksberg R., Lau Y.L. and Chung B.H.Y., Genome-wide DNA Methylation Analysis of Hong Kong Chinese Systemic Lupus Erythematosus Patients identified Hypomethylated Genes Related to Type I Interferon, Epigenomics of Common Diseases, Wellcome Trust Conference Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK, 7-10 November 2013.
Yang J., Lee P.P.W., Ying D., Ho M.H.K., Lee T.L., Yang W. and Lau Y.L., Molecular diagnosis for paediatric genetic disorders using whole exome sequencing of the next generation sequencing technology, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 17.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.
Zeng S., Yang J., Chung B.H.Y., Lau Y.L. and Yang W., EFIN: predicting the functional impact of nonsynonymous single nucleotide polymorphisms in human genome, BMC Genomics. 2014, 15: 455-463.


Researcher : Yick LW

Project Title:Defining the roles of epidermal growth factor (EGF) in the regulation of chondrocyte differentiation and endochondral bone formation
Investigator(s):Yick LW, Chan SY
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:11/2004




Researcher : Yim HCH

List of Research Outputs

Leon Y.Y., Yim H.C.H., Li C.B. and Lau A.S.Y., The role of MXD1 in influenza infection, Meeting on gene expression and signaling in the immune system, Cold spring harbor laboratory. 2014.
Pong C.H., Li C.B., Yim H.C.H. and Lau A.S.Y., Regulation of HIV-Tat induction of cytokine expression and consequent opportunistic infection by the proto-oncogene c-Myc, The Hong Kong Paediatric Society and Hong Kong Paediatrics Nurses Association joint annual scientific meeting 2013.


Researcher : Ying D

List of Research Outputs

Yang J., Lee P.P.W., Ying D., Ho M.H.K., Lee T.L., Yang W. and Lau Y.L., Molecular diagnosis for paediatric genetic disorders using whole exome sequencing of the next generation sequencing technology, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 17.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 36.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Yuen ANY

List of Research Outputs

Chiang A.K.S., Yuen A.N.Y., Ho S.M.Y., Chan C.K.Y., Lee V., Yuen H.L. and Ling S.C., The relationship between hope, rumination response styles, rumination content and psychological adjustment among childhood cancer patients and survivors, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Yuen HL

List of Research Outputs

Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.S.W., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Brain tumors of children <18-month-old: A population based study, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chan G.C.F., Shing M.K., Luk C.W., Li R.C.H., Ling S.C., Cheuk K.L.D., Lee V.W.S., Yuen H.L., Lee A.C.W., Li C.K. and Chiang A.K.S., Uncommon types of brain tumors among Chinese children, 45th Congress of the International Society of Paediatric Oncology. 2013.
Chiang A.K.S., Yuen A.N.Y., Ho S.M.Y., Chan C.K.Y., Lee V., Yuen H.L. and Ling S.C., The relationship between hope, rumination response styles, rumination content and psychological adjustment among childhood cancer patients and survivors, 45th Congress of the International Society of Paediatric Oncology. 2013.
Lee V., Luk C.W., Cheuk K.L.D., Li C.H., Ling S.C., Leung A.W.K., Yuen H.L., Chiang A.K.S. and Shing M.M.K., Long term treatment outcome of conventional high grade osteosarcoma in Hong Kong children and adolescents – from the Hong Kong paediatric haematology and oncology study group, 45th Congress of the International Society of Paediatric Oncology. 2013.


Researcher : Yung AWY

List of Research Outputs

Tso W.Y.W., Yung A.W.Y., Lau H.Y. and Chan G.C.F., Basal ganglia germinoma: MRI classifications correlates well with neurological and cognitive outcome, Journal of Paediatric Haematology & Oncology. 2013, 36(7): e443-e447.


Researcher : Yung TC

List of Research Outputs

Chung B.H.Y. and Yung T.C., 遺傳性心律失常猝死綜合症, 香港電台精靈一點, 24 June 2014, 2014.
Liu A.P.Y., Yung T.C., Chau A.K.T. and Chung B.H.Y., Unveiling the genetics of long QT syndrome: A local paediatric experience, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 20.
Liu A.P.Y., Yung T.C., Chau A.K.T. and Chung B.H.Y., Unveiling the genetics of long QT syndrome: a local paediatric experience, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.


Researcher : ZHANG J

List of Research Outputs

ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : ZHANG Y

List of Research Outputs

WANG P., Siu K.L., Zhang Y., Yang W., Kok K.H. and Jin D., Roles of a novel splice variant of human IFI16 in innate immune response, 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, June 14, 2014.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Zeng S

List of Research Outputs

ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.
Zeng S., Yang J., Chung B.H.Y., Lau Y.L. and Yang W., EFIN: predicting the functional impact of nonsynonymous single nucleotide polymorphisms in human genome, BMC Genomics. 2014, 15: 455-463.


Researcher : Zhang L

List of Research Outputs

ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Zhang Y

Project Title:Gene-gene Epistatic interaction study for systemic lupus erythematosus
Investigator(s):Zhang Y, Yang W
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:02/2013
Completion Date:01/2014


List of Research Outputs

WANG P., Siu K.L., Zhang Y., Yang W., Kok K.H. and Jin D., Roles of a novel splice variant of human IFI16 in innate immune response, 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, June 14, 2014.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Zheng J

Project Title:regulatory roles of human gammadelta-T cells in transplantation
Investigator(s):Zheng J, Tu W, Liu Y, Lau YL
Department:Paediatrics & Adolescent Med
Source(s) of Funding:Small Project Funding
Start Date:05/2014


List of Research Outputs

Chan P.L., Zheng J., Liu Y., Lam K.T., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One . 2013.
Chan P.L., Zheng J., Liu Y., Lau Y.L. and Tu W., TLR5 signaling enhances the proliferation of human allogeneic CD40-activated B cell induced CD4hiCD25+ regulatory T cells, Plos One. 2013.
HAN Y., LING M.T., Mao H., Zheng J., Liu M., Lam K.T., Liu Y., Tu W. and Lau Y.L., Influenza Virus-Induced Lung Inflammation Was Modulated by Cigarette Smoke Exposure in Mice, PLoS ONE. 2014, 9: e86166.
Zheng J., Chan P.L., Liu Y., QIN G., XIANG Z., Lam K.T., Lewis D.B., Lau Y.L. and Tu W., ICOS Regulates the Generation and Function of Human CD4+ Treg in a CTLA-4 Dependent Manner, PLoS ONE. 2013, 8: e82203.


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