SCHOOL OF CHINESE MEDICINE



Researcher : CHAN WCC

List of Research Outputs

CHAN W.C.C. and Li L., Strengthening the Spleen System to Prevent Frailty: A TCM Perspective, Ninth International Symposium on Healthy Aging. Hong Kong, 2014.
CHAN W.C.C. and Li L., The Interpretation of Chinese Medicine For “Frail Elderly”, 6th Taipei Traditional Chinese Medicine International Forum 2013. Taipei, 2014.
CHAN W.C.C. and Li L., Use Light Therapy to Treat Circadian Rhythm Sleeping Disorders of Patient with Alzheimer Disease, 2013 Chinese National Conference on Chronabiology. Nanchang, China, 2013.


Researcher : CHEN H

List of Research Outputs

CHEN H., Chen C., DENG R. and Shen J., Caveolin-1 phosphorylation plays an important role in inhibition of oxygen–/INS;glucose-deprivation-induced endothelial cell apoptosis via regulating STAT3 pathway, Journal of the Neurological Sciences. 2013, 333: e227-e228.
Chen H., Ma C.H., Cao K., Ho J.C.M., Ziea E., Wang V.T. and Zhang Z., A Systematic Review and Meta-Analysis of Herbal Medicine on Chronic Obstructive Pulmonary Diseases, Evidence-Based Complementary and Alternative Medicine. 2014, 2014: 925069.
Chen H., Lan H.Y., Roukos D.H. and Cho W.C., Application of microRNAs in diabetes mellitus, The Journal of endocrinology. 2014.
Chen H., Feng Y. and Lao L., Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute, Journal of integrative medicine. 2014, 12(3): 187-90.
Chen H., Zhong X., Huang X.R., Meng X.M., You Y.K., Chung A.C.K. and Lan H.Y., MicroRNA-29b Inhibits Diabetic Nephropathy in db/db Mice, Molecular Therapy. 2014, 22(4): 842-53.
Chen H., Li S., Cho W. and Zhang Z., The role of acupoint stimulation as an adjunct therapy for lung cancer: a systematic review and meta-analysis, BMC Complement Altern Med. 2013, 13: 362-376.
Chen H., 多样化教学在中医教育中的应用与尝试, 上海中医药大学, 2014.
Chen H., PBL教学中导师的作用与相关的导师培训, 上海中医药大学, 2014.
Chen X., CHEN H., Deng R. and Shen J., Pros and cons of current approaches for detecting peroxynitrite and their applications, Biomedical Journal. 2014, 37: 120-126.
Lan H.Y. and Chen H., TGF~!b/Smad系统与肾脏炎症和纤维化调节, 生理科学进展, Beijing, Higher Education Press, 2014.
Tong Y. and Chen H., An Implement of Outcome-based Approaches to Student Learning in Common Core Curriculum, 12th Meeting of The Consortium for Globalization of Chinese Medicine. 2013, 85.
Tong Y., Feng Y. and Chen H., Chinese Medicine Programme of the Continuing Education in HKU, 12th Meeting of The Consortium for Globalization of Chinese Medicine. 2013, 275.
Wei L.H., Huang X.R., Zhang Y., Li Y.Q., Chen H., Heuchel R., Yan B.P., Yu C.M. and Lan H.Y., Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension, PLoS One. 2013, 8(7): e70195.
Wei L.H., Huang X.R., Zhang Y., Li Y.Q., Chen H., Yan B.P., Yu C.M. and Lan H.Y., Smad7 inhibits angiotensin II-induced hypertensive cardiac remodelling, Cardiovascular Research. 2013, 99(4): 665-73.
Yeung W.F., Chen H., Chung K.F. and Zhang Z., Clinical trials of traditional Chinese medicine for insomnia: current status and future directions, World Journal of Sleep Medicine. 2014, 1: 54-58.
Zhao B.X., Chen H., Shen X.Y. and Lao L., Can moxibustion, an ancient treatment modality, be evaluated in a double-blind randomized controlled trial? - A narrative review, J Integrative Medicine. 2014, 12(3): 131-134.


Researcher : CHEN X

List of Research Outputs

Chen X., CHEN H., Deng R. and Shen J., Pros and cons of current approaches for detecting peroxynitrite and their applications, Biomedical Journal. 2014, 37: 120-126.
Pan Y., ZHAO L., Chen X., GU Y., Shen J. and Liu L.M., The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis, Asian Pacific Journal of Cancer Prevention. 2013, 14: 5761-5767.
Shen J., Chen X., CHEN X. and Deng R., Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine, Integrative Medicine International. 2014, 1: 5-18.
Xu M., Chen X., Gu Y., Peng T., Yang D., Chang R.C.C., So K.F., Liu K. and Shen J., Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury, J Ethnopharmacol. 2013, 150(1): 116-24.


Researcher : CHENG Y

List of Research Outputs

CHENG Y., YANG C., ZHAO J. and Rong J., Purification of Z-Ligustilide by AgNO3-Impregnated Silica Gel, 硝酸银改性硅胶柱色谱法纯化川芎精油中的藁本内酯, Chinese Journal of Modern Applied Pharmacy. 中国现代应用药学, 2014, 31 (5): 552-555.
YANG C., ZHAO J., CHENG Y., Li X.C. and Rong J., Bioactivity-guided fractionation identifies amygdalin as a potent neurotrophic agent from herbal medicine semen persicae extract, Biomed Research International. 2014, 2014: 306857-306867.
YANG C., Pei W.J., ZHAO J., CHENG Y., Zheng X.H. and Rong J., Bornyl caffeate induces apoptosis in human breast cancer MCF-7 cells via the ROS- and JNK-mediated pathways, Acta Pharmacol Sin.. 2014, 35(1): 113-23.
YANG C., CHENG Y., ZHAO J. and Rong J., Research progress on the pharmacological activities of dihydroflavones, 二氢黄酮的药理活性研究进展, International Journal of Traditional Chinese Medicine . 国际中医中药杂志, 2014, 4: 370-375.


Researcher : CHEUNG F

List of Research Outputs

CHEUNG F., Wang X., Wang N., Yuen R.M.F., Zia T.C., Tong Y., Wong V.C.W. and Feng Y., Chinese Medicines as an Adjuvant Therapy for Unresectable Hepatocellular Carcinoma during Transarterial Chemoembolization: A Meta-Analysis of Randomized Controlled Trials, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2013, 2013:487919.: doi: 10.1155/2013/487919.
Chan L.E.I., CHEUNG F. and Feng Y., Clinical research progress on hepatocellular carcinoma treated by Chinese medicine . 中醫藥防治原發性肝癌的臨床研究進展, Hong Kong Chinese Medical Journal, 2013.


Researcher : CHEUNG HP

List of Research Outputs

Chu S.M.E., Sze C.W., Cheung H.P., Liu Q., Ng T.B. and Tong Y., An In Vitro and In Vivo Investigation of the Antimetastatic Effects of a Chinese Medicinal Decoction, Erxian Decoction, on Human Ovarian Cancer Models, Integrative Cancer Therapies. SAGE Journals, 2013, 12: 336-346.
Sze C.W., Lai Y.M., Zhang Y., Ng T.B., Tong Y., WONG K.L., CHEUNG H.P., LU J., ZHANG L. and LEIGH A.B., Novel Bioactive Protein Isolated from Chinese Yam for Menopause, The 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria. 2013.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof, US Patent and Trademark Office. US20130217626 A1, 2013.
ZHANG L., CHEUNG H.P., Lee C.K.F., Ng T.B., Zhang Y., Lao L. and Sze C.W., Proteomics Analysis of the Ovarian Tissues of Sprague-Dawley Rats of Different Ages to Identify Aging-Associated Changes, Ninth International Symposium on Healthy Aging “Aging with Confidence”, Hong Kong. 2014.


Researcher : Cai X

List of Research Outputs

MA C.H., Lin W., Lui S., Cai X., Wong V., Ziea E. and Zhang Z., Efficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials., Asian J Androl. . 2013, 15(4): 471-82.


Researcher : Cao K

List of Research Outputs

Chen H., Ma C.H., Cao K., Ho J.C.M., Ziea E., Wang V.T. and Zhang Z., A Systematic Review and Meta-Analysis of Herbal Medicine on Chronic Obstructive Pulmonary Diseases, Evidence-Based Complementary and Alternative Medicine. 2014, 2014: 925069.


Researcher : Chan YS

List of Research Outputs

Chan Y.S., Zhang Y., Sze C.W. and Ng T.B., A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans, Journal of Enzyme Inhibition and Medicinal Chemistry. UK, 2013, 2013: 1475-6374.


Researcher : Chen H

List of Research Outputs

CHEN H., Chen C., DENG R. and Shen J., Caveolin-1 phosphorylation plays an important role in inhibition of oxygen–/INS;glucose-deprivation-induced endothelial cell apoptosis via regulating STAT3 pathway, Journal of the Neurological Sciences. 2013, 333: e227-e228.
Chen H., Ma C.H., Cao K., Ho J.C.M., Ziea E., Wang V.T. and Zhang Z., A Systematic Review and Meta-Analysis of Herbal Medicine on Chronic Obstructive Pulmonary Diseases, Evidence-Based Complementary and Alternative Medicine. 2014, 2014: 925069.
Chen H., Lan H.Y., Roukos D.H. and Cho W.C., Application of microRNAs in diabetes mellitus, The Journal of endocrinology. 2014.
Chen H., Feng Y. and Lao L., Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute, Journal of integrative medicine. 2014, 12(3): 187-90.
Chen H., Zhong X., Huang X.R., Meng X.M., You Y.K., Chung A.C.K. and Lan H.Y., MicroRNA-29b Inhibits Diabetic Nephropathy in db/db Mice, Molecular Therapy. 2014, 22(4): 842-53.
Chen H., Li S., Cho W. and Zhang Z., The role of acupoint stimulation as an adjunct therapy for lung cancer: a systematic review and meta-analysis, BMC Complement Altern Med. 2013, 13: 362-376.
Chen H., 多样化教学在中医教育中的应用与尝试, 上海中医药大学, 2014.
Chen H., PBL教学中导师的作用与相关的导师培训, 上海中医药大学, 2014.
Chen X., CHEN H., Deng R. and Shen J., Pros and cons of current approaches for detecting peroxynitrite and their applications, Biomedical Journal. 2014, 37: 120-126.
Lan H.Y. and Chen H., TGF~!b/Smad系统与肾脏炎症和纤维化调节, 生理科学进展, Beijing, Higher Education Press, 2014.
Tong Y. and Chen H., An Implement of Outcome-based Approaches to Student Learning in Common Core Curriculum, 12th Meeting of The Consortium for Globalization of Chinese Medicine. 2013, 85.
Tong Y., Feng Y. and Chen H., Chinese Medicine Programme of the Continuing Education in HKU, 12th Meeting of The Consortium for Globalization of Chinese Medicine. 2013, 275.
Wei L.H., Huang X.R., Zhang Y., Li Y.Q., Chen H., Heuchel R., Yan B.P., Yu C.M. and Lan H.Y., Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension, PLoS One. 2013, 8(7): e70195.
Wei L.H., Huang X.R., Zhang Y., Li Y.Q., Chen H., Yan B.P., Yu C.M. and Lan H.Y., Smad7 inhibits angiotensin II-induced hypertensive cardiac remodelling, Cardiovascular Research. 2013, 99(4): 665-73.
Yeung W.F., Chen H., Chung K.F. and Zhang Z., Clinical trials of traditional Chinese medicine for insomnia: current status and future directions, World Journal of Sleep Medicine. 2014, 1: 54-58.
Zhao B.X., Chen H., Shen X.Y. and Lao L., Can moxibustion, an ancient treatment modality, be evaluated in a double-blind randomized controlled trial? - A narrative review, J Integrative Medicine. 2014, 12(3): 131-134.


Researcher : Chen J

Project Title:The development of multimedia tearching and learning system in TCM -prescrption subject
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:07/2011


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:01/2012
Completion Date:11/2013


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A (ITS/073/11FP)
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:Inhibiting breast cancer metastasis through TGF-β1-Induced Epithelial-Mesenchymal Transition (EMT) by Isoliquiritigenin (ISL)
Investigator(s):Chen J, Guan X
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012
Completion Date:11/2013


Project Title:Ninth AACR-Japanese Cancer Association Joint Conference: Breakthroughs in Basic and Translational Cancer Research; Isoliquiritigenin promotes breast cancer chemosensitivity by limiting cancer stem cells targeting aberrant β-catenin signaling
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:02/2013


Project Title:Identification and characterization of natural LDH-A inhibitor from Chinese Herbs for breast cancer prevention.
Investigator(s):Chen J, Wang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2013
Completion Date:06/2014


Project Title:Exploring cancer preventive function of a dietary compound Isoliquiritigenin by limiting breast cancer stem cells via beta-catenin/COX-2 pathway
Investigator(s):Chen J, Wang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2013


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2013


Project Title:A randomized, controlled trial of the efficacy of Guolin-Qigong on body-mind health of Chinese women with breast cancer
Investigator(s):Chen J, Ng SM
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014
Completion Date:07/2014


Project Title:Relationships between constitutional types of traditional Chinese medicine and Breast cancer
Investigator(s):Chen J, Sun S
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Chen J., Association of Emotional Disorders with the Physical Exercising Habits among Hospital Discharged Breast Cancer Patients in Hong Kong, 12th Meeting of Consortium for Globalization of Chinese Medicine . 2013.
Chen J., Breast Cancer prevention , 10 annual academic conference in HK by Registration HK TCM . 2013.
Chen J., How do TCM research on Breast cancer, How do TCM research on Breast cancer. 2014.
Chen J., Target on LDH-A by Chinese medicine, Jiangsu institution of TCM . 2013.
Chen J., unbanlence of breast Cancer in Left and Righ side , 4th international Chinese Medicine conference in Chengdu . 2013.
Chen J., 方劑學, 2013.
Cheng C., Wang Z. and Chen J., Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine, Evid Based Complement Alternat Med.. 2014.
GU Y., Chen J. and Shen J., Herbal Medicines for Ischemic Stroke: Combating Inflammation as Therapeutic Targets, Journal of Neuroimmune Pharmacology 31. 2014, 9: 313-339.
Han S., Tang Q., zheng F., zhao S., Wu J. and Chen J., Repression of Intergrin-linked Kinase by Antidiabetes Drugs through Cross-talk of PPARγ- and AMPKα-dependent Signaling: Role of AP-2α and Sp1., Cell Signal. 2014, 26 (3): 639-647.
Han S., Tang Q., Zheng F., Zhao S.Y., Wang Z. and Chen J., Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth., Molecular cancer. 2014.
Han S., Chen J., Wang Z., wu J., zheng F. and zhao S., Targeting EP4 by Curcumin through cross Talks of AMP-dependent Kinase Alpha and p38 Mitogen-activated Protein Kinase Signaling: The Role of PGC-1α and Sp1., Cell Signal.. 2013, 2566-2574.
Liang J., Chen J., Tan Z., Peng J., Zheng X., Nishiura K., Ng J., Wang Z., Wang D., Chen Z. and Liu L., Extracts of medicinal herb Sanguisorba officinalis inhibit the entry of human immunodeficiency virus type one. , JFDA. 2013, 21(4): 52-58.
SUN Y., Liu P., JIA L., He Y., Wang Z., WANG N. and Chen J., Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: a cross-sectional survey, Journal of translational medicine. 2014.
Wang Z., WANG N., Han S., Wang D., Mo S., Yu L., Huang H., Tsui K., Shen J. and Chen J., Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Growth And Neoangiogenesis Via Blocking Vegf/vegfr-2 Signaling Pathway, Plos One. Plos, 2013, 8: 14.


Researcher : Chen X

Project Title:Comparison of different ginsenosides on neurogenesis in vitro and in vivo
Investigator(s):Chen X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2014


List of Research Outputs

Chen X., CHEN H., Deng R. and Shen J., Pros and cons of current approaches for detecting peroxynitrite and their applications, Biomedical Journal. 2014, 37: 120-126.
Pan Y., ZHAO L., Chen X., GU Y., Shen J. and Liu L.M., The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis, Asian Pacific Journal of Cancer Prevention. 2013, 14: 5761-5767.
Shen J., Chen X., CHEN X. and Deng R., Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine, Integrative Medicine International. 2014, 1: 5-18.
Xu M., Chen X., Gu Y., Peng T., Yang D., Chang R.C.C., So K.F., Liu K. and Shen J., Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury, J Ethnopharmacol. 2013, 150(1): 116-24.


Researcher : Chen X

List of Research Outputs

Chen X., CHEN H., Deng R. and Shen J., Pros and cons of current approaches for detecting peroxynitrite and their applications, Biomedical Journal. 2014, 37: 120-126.
Pan Y., ZHAO L., Chen X., GU Y., Shen J. and Liu L.M., The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis, Asian Pacific Journal of Cancer Prevention. 2013, 14: 5761-5767.
Shen J., Chen X., CHEN X. and Deng R., Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine, Integrative Medicine International. 2014, 1: 5-18.
Xu M., Chen X., Gu Y., Peng T., Yang D., Chang R.C.C., So K.F., Liu K. and Shen J., Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury, J Ethnopharmacol. 2013, 150(1): 116-24.


Researcher : Cheung KCP

List of Research Outputs

Tsang C.M., Cheung Y.C., Lui W.Y.V., Yip Y.L., Zhang G., LIN W., Cheung K.C.P., Feng Y. and Tsao G.S.W., Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts, BMC Cancer. 2013, 13: 619.


Researcher : Chu SME

List of Research Outputs

Chu S.M.E., Sze C.W., Cheung H.P., Liu Q., Ng T.B. and Tong Y., An In Vitro and In Vivo Investigation of the Antimetastatic Effects of a Chinese Medicinal Decoction, Erxian Decoction, on Human Ovarian Cancer Models, Integrative Cancer Therapies. SAGE Journals, 2013, 12: 336-346.


Researcher : DENG R

List of Research Outputs

CHEN H., Chen C., DENG R. and Shen J., Caveolin-1 phosphorylation plays an important role in inhibition of oxygen–/INS;glucose-deprivation-induced endothelial cell apoptosis via regulating STAT3 pathway, Journal of the Neurological Sciences. 2013, 333: e227-e228.
Chen X., CHEN H., Deng R. and Shen J., Pros and cons of current approaches for detecting peroxynitrite and their applications, Biomedical Journal. 2014, 37: 120-126.
Shen J., Chen X., CHEN X. and Deng R., Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine, Integrative Medicine International. 2014, 1: 5-18.


Researcher : Deng R

List of Research Outputs

CHEN H., Chen C., DENG R. and Shen J., Caveolin-1 phosphorylation plays an important role in inhibition of oxygen–/INS;glucose-deprivation-induced endothelial cell apoptosis via regulating STAT3 pathway, Journal of the Neurological Sciences. 2013, 333: e227-e228.
Chen X., CHEN H., Deng R. and Shen J., Pros and cons of current approaches for detecting peroxynitrite and their applications, Biomedical Journal. 2014, 37: 120-126.
Shen J., Chen X., CHEN X. and Deng R., Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine, Integrative Medicine International. 2014, 1: 5-18.


Researcher : Feng Y

Project Title:The inhibitory action of berberine on hepatocellular carcinoma
Investigator(s):Feng Y, Man K, Tong Y, Tsao GSW
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011
Completion Date:09/2013


Project Title:The anti-metastasis effect and its underlying mechanism of genipin derived from Chinese herbal Gardenia jasminoides in hepatocellular caricinoma cell and animal models
Investigator(s):Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012
Completion Date:03/2014


Project Title:Exploring the mechanism underlying the anti-invasion effect of Chinese Medicine Formula Gegen Qinlian Decoction in Human Renal Carcinoma
Investigator(s):Feng Y, Wang N
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:12th The Consortium for Globalization of Chinese Medicine (CGCM); Modern scientific studies of Chinese herbal medicine treatment of renal diseases: challenges and opportunities
Investigator(s):Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


Project Title:The inhibitory effect of berberine on tumour associated macrophages in HCC tumour microenvironment
Investigator(s):Feng Y, Wang N
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:04/2014


List of Research Outputs

CHEUNG F., Wang X., Wang N., Yuen R.M.F., Zia T.C., Tong Y., Wong V.C.W. and Feng Y., Chinese Medicines as an Adjuvant Therapy for Unresectable Hepatocellular Carcinoma during Transarterial Chemoembolization: A Meta-Analysis of Randomized Controlled Trials, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2013, 2013:487919.: doi: 10.1155/2013/487919.
Chan L.E.I., CHEUNG F. and Feng Y., Clinical research progress on hepatocellular carcinoma treated by Chinese medicine . 中醫藥防治原發性肝癌的臨床研究進展, Hong Kong Chinese Medical Journal, 2013.
Chen H., Feng Y. and Lao L., Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute, Journal of integrative medicine. 2014, 12(3): 187-90.
Feng Y., Anticancer effects and the mechanism of Chinese medicines: from effect screening to mechanism studies. , HK-Swiss Mini-symposium on Traditional Chinese Medicine (Novartis Mini-symposium). 2013.
Feng Y., Editor, In: Feng Yibin (2011-), Journal of Bioequivalence & Bioavailability. Henderson NV 89074-7722, USA, OMICS Group Incorporation, 2013.
Feng Y., Hong Kong Chinese Medical Journal, In: 陈抗生, 邓春, 温桂荣, 赵中正, 冯奕斌, 吴俊来, 王如跃, 黄约爱,, Hong Kong Chinese Medical Journal. 香港中医杂志, Hong Kong, 香港中医杂志出版社, 2014.
Feng Y., Matching Grant for the Gaia Family Trust for immunology and stem cell research in Chinese Medicines and natural products, UGC (Government Matching Grant Scheme) . 2014.
Feng Y., Member of journal editorship, In: Feng Yibin, Evidence-Based Complementary and Alternative Medicine. USA, Hindawi Publishing Corporation, 2013.
Feng Y., Zhong G., Zhong Y., Yao C. and Ban S., National Textbook for diet therapy. 2013.
Feng Y., The Editoral Board member, Recent Patents on Recent Patents on Food, Nutrition & Agriculture. USA, BENTHAM SCIENCE PUBLISHERS LTD., 2013.
Lam P.Y. and Feng Y., Relationship exploration of diabetic combined with cholangiocarcinoma and one case report. 糖尿病合併膽管癌關係探討及病案分析, Hong Kong Chinese Medical Journal, 2013, 26-29.
TAN H.Y., Wang N., Tsao G.S.W., Zhang Z. and Feng Y., Suppression of Vascular Endothelial Growth Factor via Inactivation of Eukaryotic Elongation Factor 2 by Alkaloids in Coptidis rhizoma in Hepatocellular Carcinoma, Integrative Cancer Therapies. 2013.
Tong Y., Feng Y. and Chen H., Chinese Medicine Programme of the Continuing Education in HKU, 12th Meeting of The Consortium for Globalization of Chinese Medicine. 2013, 275.
Tsang C.M., Cheung Y.C., Lui W.Y.V., Yip Y.L., Zhang G., LIN W., Cheung K.C.P., Feng Y. and Tsao G.S.W., Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts, BMC Cancer. 2013, 13: 619.
Wang N. and Feng Y., A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma, Biochim Biophys Acta-Molecular Cell research. 2013, 1833(12):2890-2899.: doi: 10.1016/j.bbamcr.2013.07.018.
Wang N., Feng Y., ZHU M., Siu A.F.M., Ng K.M. and Che C.M., A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2013, 1833: 2890-2899.
Wang N., ZHU M., Wang X., TAN H.Y., Tsao G.S.W. and Feng Y., Berberine-induced tumor suppressor p53 up-regulation gets involved in the regulatory network of MIR-23a in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2014.
Wang N., Zhu M., Tsao G.S.W., Man K., Zhang Z. and Feng Y., MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma, Molecular Cancer. Elsevier, 2013, 12(1):119.: doi: 10.1186/1476-4598-12-119.
Wang Y. and Feng Y., Exploring localization of Chinese medicine in the University of Hong Kong. 香港大學中醫教育本土化的有益探索, 甘肅中醫雜誌, 2013.


Researcher : GU Y

List of Research Outputs

GU Y., Chen J. and Shen J., Herbal Medicines for Ischemic Stroke: Combating Inflammation as Therapeutic Targets, Journal of Neuroimmune Pharmacology 31. 2014, 9: 313-339.
Pan Y., ZHAO L., Chen X., GU Y., Shen J. and Liu L.M., The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis, Asian Pacific Journal of Cancer Prevention. 2013, 14: 5761-5767.
Shen J. and GU Y., 1. Shen JG*, Gu Y. Insights into mechanisms of blood brain barrier permeability: Roles of free radicals, matrix metalloproteinases and caveolin-1. , Systems Biology of Oxidative Stress. (Eds. Ismail Laher), Springer 2014,. 2014, pp 2049-2067.
Xu M., Chen X., Gu Y., Peng T., Yang D., Chang R.C.C., So K.F., Liu K. and Shen J., Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury, J Ethnopharmacol. 2013, 150(1): 116-24.


Researcher : Gu Y

List of Research Outputs

GU Y., Chen J. and Shen J., Herbal Medicines for Ischemic Stroke: Combating Inflammation as Therapeutic Targets, Journal of Neuroimmune Pharmacology 31. 2014, 9: 313-339.
Pan Y., ZHAO L., Chen X., GU Y., Shen J. and Liu L.M., The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis, Asian Pacific Journal of Cancer Prevention. 2013, 14: 5761-5767.
Shen J. and GU Y., 1. Shen JG*, Gu Y. Insights into mechanisms of blood brain barrier permeability: Roles of free radicals, matrix metalloproteinases and caveolin-1. , Systems Biology of Oxidative Stress. (Eds. Ismail Laher), Springer 2014,. 2014, pp 2049-2067.
Xu M., Chen X., Gu Y., Peng T., Yang D., Chang R.C.C., So K.F., Liu K. and Shen J., Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury, J Ethnopharmacol. 2013, 150(1): 116-24.


Researcher : He Y

List of Research Outputs

SUN Y., Liu P., JIA L., He Y., Wang Z., WANG N. and Chen J., Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: a cross-sectional survey, Journal of translational medicine. 2014.


Researcher : Hu KY

Project Title:The 6th World Congress of Chinese Medicine 2009 The International Spread Characteristics of Traditional Chinese Medicine
Investigator(s):Hu KY
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2009




Researcher : JIA L

List of Research Outputs

SUN Y., Liu P., JIA L., He Y., Wang Z., WANG N. and Chen J., Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: a cross-sectional survey, Journal of translational medicine. 2014.


Researcher : LEIGH AB

List of Research Outputs

Sze C.W., Lai Y.M., Zhang Y., Ng T.B., Tong Y., WONG K.L., CHEUNG H.P., LU J., ZHANG L. and LEIGH A.B., Novel Bioactive Protein Isolated from Chinese Yam for Menopause, The 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria. 2013.


Researcher : LO KC

List of Research Outputs

LO K.C. and Li L., A Study of the Ministerial Fire, Forum on Traditional Chinese Medicine. 2013, 28(6): 11-12.
LO K.C. and Li L., Discussing the Thinking of Yi-ology on the Burn and Plain Cool Methods in Acupuncture Manipulation, Hong Kong Chinese Medicine Journal. 2014, 9(1): 69-70.
LO K.C. and Li L., Dyndrome Differentiation of Six Channels Theory with Dyndrome Differentiation of Three-Yin and Three-Yang Theory, Guangming Journal of Chinese Medicine. 2014, 29(5): 915-917.
LO K.C. and Li L., Tao of Changes and Tao of Medicine- Concept of Position and Time in San Fu Tian Jiu Therapy, 2013 Chinese National Conference on Chronabiology. Nanchang, China, 2013.
LO K.C. and Li L., Tao of Changes and Tao of Medicine-The Influence of the Philosophy of “Concept of Time and Space” in Zhou Yi on the Theories Development of Chinese Medicine, 6th Taipei Traditional Chinese Medicine International Forum 2013. Taipei, 2014.
LO K.C. and Li L., Tao of Changes and Tao of Medicine-The Influence of the Philosophy of “Concept of Time and Space” in Zhou Yi on the Theories Development of Chinese Medicine, Journal Beijing University of Chemical Technology (Social Sciences Edition). 2014, 85(1): 58-63.
LO K.C. and Li L., The Impact of the Philosophy of “Concept of Time and Space” in“ZhouYi” on the Theories Development of Traditional Chinese Medicine, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.
LO K.C. and Li L., Visceral Manifestation Theory and Concept of Natural Law, Henan Traditional Chinese Medicine. 2013, 33(11): 1836-1837.
Li L., Tung C...W... and LO K.C., The Origin of Meridians, Chinese Medicine. 2014, (5): 71-74.
Liu J...B..., LO K.C. and Li L., Clinical Research Progress of Pediatric Massage Therapy Applied to Infantile Constipation, Chinese Manipulation & Rehabilitation Medicine. 2013, 4(9): 44-48.
WANG Z., WONG R...N...S..., Sze C.W., NG T...B..., TO W...S..., ZHANG W., LO K.C., YAU T... and Li L., Mechanistic Study of Circadian Rhythms of Tryptophan Hydroxylase and Serotonin Receptors Involved in Acupuncture-induced Analgesia, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.
Yum T.P., LO K.C. and Li L., Review of the Impact of Acupuncture on Physiological Functions of Middle-distance and Long-distance Runners, 6th Taipei Traditional Chinese Medicine International Forum 2013. Taipei, 2014.
ZHU L., LO K.C., Li L. and ZHANG W., The Clinical Research Progress of Tian Jiu Therapy for Infantile Bronchial Asthma, Hunan Journal of Traditional Chinese Medicine. 2013, 29(12): 159-160.
ZHU L., Yum T.P., LO K.C. and Li L., Wrist-ankle Acupuncture for the Treatment of Pain Symptoms: A Systematic Review and Meta-analysis, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.


Researcher : LU J

List of Research Outputs

Sze C.W., Lai Y.M., Zhang Y., Ng T.B., Tong Y., WONG K.L., CHEUNG H.P., LU J., ZHANG L. and LEIGH A.B., Novel Bioactive Protein Isolated from Chinese Yam for Menopause, The 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria. 2013.


Researcher : Lao L

Project Title:2014 International Research Congress on Integrative Medicine and Health; Acupuncture and Complementary Medicine in Pain Management/Acupuncture and Mindfulness-Based Stress Reduction among Female Child Abuse Survivors: A Randomized Waitlist-Controlled Pilot Study
Investigator(s):Lao L
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2014


List of Research Outputs

Chen H., Feng Y. and Lao L., Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute, Journal of integrative medicine. 2014, 12(3): 187-90.
ZHANG L., CHEUNG H.P., Lee C.K.F., Ng T.B., Zhang Y., Lao L. and Sze C.W., Proteomics Analysis of the Ovarian Tissues of Sprague-Dawley Rats of Different Ages to Identify Aging-Associated Changes, Ninth International Symposium on Healthy Aging “Aging with Confidence”, Hong Kong. 2014.
Zhao B.X., Chen H., Shen X.Y. and Lao L., Can moxibustion, an ancient treatment modality, be evaluated in a double-blind randomized controlled trial? - A narrative review, J Integrative Medicine. 2014, 12(3): 131-134.


Researcher : Li L

Project Title:12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM); Mechanistic Study of Circadian Rhythms of Tryptophan Hydroxylase and Serotonin Receptors Involved in Acupuncture-Induced Analgesia
Investigator(s):Li L
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


List of Research Outputs

CHAN W.C.C. and Li L., Strengthening the Spleen System to Prevent Frailty: A TCM Perspective, Ninth International Symposium on Healthy Aging. Hong Kong, 2014.
CHAN W.C.C. and Li L., The Interpretation of Chinese Medicine For “Frail Elderly”, 6th Taipei Traditional Chinese Medicine International Forum 2013. Taipei, 2014.
CHAN W.C.C. and Li L., Use Light Therapy to Treat Circadian Rhythm Sleeping Disorders of Patient with Alzheimer Disease, 2013 Chinese National Conference on Chronabiology. Nanchang, China, 2013.
LO K.C. and Li L., A Study of the Ministerial Fire, Forum on Traditional Chinese Medicine. 2013, 28(6): 11-12.
LO K.C. and Li L., Discussing the Thinking of Yi-ology on the Burn and Plain Cool Methods in Acupuncture Manipulation, Hong Kong Chinese Medicine Journal. 2014, 9(1): 69-70.
LO K.C. and Li L., Dyndrome Differentiation of Six Channels Theory with Dyndrome Differentiation of Three-Yin and Three-Yang Theory, Guangming Journal of Chinese Medicine. 2014, 29(5): 915-917.
LO K.C. and Li L., Tao of Changes and Tao of Medicine- Concept of Position and Time in San Fu Tian Jiu Therapy, 2013 Chinese National Conference on Chronabiology. Nanchang, China, 2013.
LO K.C. and Li L., Tao of Changes and Tao of Medicine-The Influence of the Philosophy of “Concept of Time and Space” in Zhou Yi on the Theories Development of Chinese Medicine, 6th Taipei Traditional Chinese Medicine International Forum 2013. Taipei, 2014.
LO K.C. and Li L., Tao of Changes and Tao of Medicine-The Influence of the Philosophy of “Concept of Time and Space” in Zhou Yi on the Theories Development of Chinese Medicine, Journal Beijing University of Chemical Technology (Social Sciences Edition). 2014, 85(1): 58-63.
LO K.C. and Li L., The Impact of the Philosophy of “Concept of Time and Space” in“ZhouYi” on the Theories Development of Traditional Chinese Medicine, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.
LO K.C. and Li L., Visceral Manifestation Theory and Concept of Natural Law, Henan Traditional Chinese Medicine. 2013, 33(11): 1836-1837.
Li L., A Systematic Review of Experimental Studies on Midnight-Noon Ebb-Flow Acupuncture, China Journal of Traditional Chinese Medicine and Pharmacy. 2014, 29(3): 816-819.
Li L., Acupuncture Prose Poems and Academic Knowledge Inheritance, International Conference on Imperial Examination and Cifu. Hong Kong, 2014.
Li L., Applied Acupuncture Point Location. 實用臨床取穴, Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 448.
Li L., Applied Acupuncture Point Location (In hardcover). 實用臨床取穴(精裝本), Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 448.
Li L., Applied Acupuncture Point Location (In traditional Chinese version). 實用臨床取穴(繁體版), Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 448.
Li L., Applied Acupuncture Point Location(In traditional Chinese version and hardcover). 實用臨床取穴(繁體精裝本), Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 448.
Li L., Emendations and Scholiumes on “Classic of Acupuncture & Moxibustion on Midnight-noon Ebb-flow”. 《子午流注針經》校注, Hong Hong, Linlan Chinese Medicine Culture Co. Ltd., 2014, 213.
Li L., Exegesis of “Zhou Yi”. 《周易》直解, Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 301.
Li L., Exegesis of “Zhou Yi” (In traditional Chinese version). 《周易》直解(繁體版), Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 301.
Li L., Impact of Nine-palaces and Eight-winds Theory on Traditional Time-acupuncture Methodology, 2013 Chinese National Conference on Chronabiology. Nanchang, China, 2013.
Li L., Methods of Acupuncture at Pain Point in “The Yellow Emperor's Internal Classic”, 6th Taipei Traditional Chinese Medicine International Forum 2013. Taipei, 2014.
Li L., On the Impact of the Pre-Qin Military Science to the Theory of Traditional Chinese Medicine, Forum on Traditional Chinese Medicine. 2013, 28(5): 51.
Li L., The Name Discrimination between “Orthopaedics and Traumatology” and “Traumatology and Orthopaedics”, Hong Kong Chinese Medicine Journal. 2013, 8(3): 9-10.
Li L., The Name Discrimination between “Orthopaedics and Traumatology” and “Traumatology and Orthopaedics”, Hong Kong Chinese Medicine Journal. Hong Kong, 《香港中醫雜誌》雜誌社, 2013, 8(3): 9-10.
Li L., Tung C...W... and LO K.C., The Origin of Meridians, Chinese Medicine. 2014, (5): 71-74.
Liu J...B..., LO K.C. and Li L., Clinical Research Progress of Pediatric Massage Therapy Applied to Infantile Constipation, Chinese Manipulation & Rehabilitation Medicine. 2013, 4(9): 44-48.
WANG Z., WONG R...N...S..., Sze C.W., NG T...B..., TO W...S..., ZHANG W., LO K.C., YAU T... and Li L., Mechanistic Study of Circadian Rhythms of Tryptophan Hydroxylase and Serotonin Receptors Involved in Acupuncture-induced Analgesia, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.
Yum T.P., LO K.C. and Li L., Review of the Impact of Acupuncture on Physiological Functions of Middle-distance and Long-distance Runners, 6th Taipei Traditional Chinese Medicine International Forum 2013. Taipei, 2014.
Yum T.P. and Li L., The Experimental Study Progress of Acupuncture on Rhythm, 2013 Chinese National Conference on Chronabiology. Nanchang, China, 2013.
ZHU L. and Li L., Different View on the Function of Gallbladder, Asia-Pacific Traditional Medicine. 2013, 9(8): 60-61.
ZHU L., LO K.C., Li L. and ZHANG W., The Clinical Research Progress of Tian Jiu Therapy for Infantile Bronchial Asthma, Hunan Journal of Traditional Chinese Medicine. 2013, 29(12): 159-160.
ZHU L., Yum T.P., LO K.C. and Li L., Wrist-ankle Acupuncture for the Treatment of Pain Symptoms: A Systematic Review and Meta-analysis, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.


Researcher : Liu C

Project Title:6th Annual Rocky Mountain Bioinformatics Conference CADEG, a Set of Software Tools for High Resolution Identification of Potential Chromosomal Abnormalities
Investigator(s):Liu C
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2008




Researcher : Liu N

List of Research Outputs

Liu N., Clinical Observations on Deep Needling of Points Dubi and Medial Xiyan for the Treatment of Knee Osteoarthritis, 深刺犢鼻、內膝眼穴治療膝骨關節炎臨床觀察, Shanghai Journal of Acupuncture and Moxibustion. 上海針灸雜志, 中国上海, 2013, 857-858.
Liu N., Discussing “Fan Zhen Jie Ci”, 辨“燔針劫刺”, Chinese Acupuncture & Moxibustion . 中國針灸, 2013, 33(S1): 102-104.
Liu N., The analysis of "pain-point needling", 析“以痛為輸”, Journal Of Clinical Acupuncture And Moxibustion . 針灸臨床雜誌, 2014, 30: 55-57.


Researcher : Liu Q

List of Research Outputs

Chu S.M.E., Sze C.W., Cheung H.P., Liu Q., Ng T.B. and Tong Y., An In Vitro and In Vivo Investigation of the Antimetastatic Effects of a Chinese Medicinal Decoction, Erxian Decoction, on Human Ovarian Cancer Models, Integrative Cancer Therapies. SAGE Journals, 2013, 12: 336-346.
Zhong L., Tong Y., Tang G.W.K., Zhang Z., Choi W.K., Cheng K., Sze C.W., Wai K., Liu Q. and Yu X., A randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong perimenopausal women, Menopause . 2013, 20: 767-776.


Researcher : MA CH

List of Research Outputs

Chen H., Ma C.H., Cao K., Ho J.C.M., Ziea E., Wang V.T. and Zhang Z., A Systematic Review and Meta-Analysis of Herbal Medicine on Chronic Obstructive Pulmonary Diseases, Evidence-Based Complementary and Alternative Medicine. 2014, 2014: 925069.
MA C.H., Lian L.W., Leung L.S., Wong V.T., Ziea E.T. and Zhang Z., Chinese herbal medicine for benign prostatic hyperplasia: systematic review and meta-analysis, Asian Journal of Andrology . 2013, 15: 471-482.
MA C.H., Lin W., Lui S., Cai X., Wong V., Ziea E. and Zhang Z., Efficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials., Asian J Androl. . 2013, 15(4): 471-82.


Researcher : Ma CH

List of Research Outputs

Chen H., Ma C.H., Cao K., Ho J.C.M., Ziea E., Wang V.T. and Zhang Z., A Systematic Review and Meta-Analysis of Herbal Medicine on Chronic Obstructive Pulmonary Diseases, Evidence-Based Complementary and Alternative Medicine. 2014, 2014: 925069.
MA C.H., Lian L.W., Leung L.S., Wong V.T., Ziea E.T. and Zhang Z., Chinese herbal medicine for benign prostatic hyperplasia: systematic review and meta-analysis, Asian Journal of Andrology . 2013, 15: 471-482.
MA C.H., Lin W., Lui S., Cai X., Wong V., Ziea E. and Zhang Z., Efficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials., Asian J Androl. . 2013, 15(4): 471-82.


Researcher : Man MSC

List of Research Outputs

Zhang Z., WANG D., Man M.S.C., Ng R., McAlonan G.M., Wong H.K., Wong W., Lee J. and Tan Q.R., Platelet 5-HT1A receptor correlates with major depressive disorder in drug-free patients, Progress in Neuro-Psychopharmacology & Biological Psychiatry. Elsevier, 2014, 53: 74-79.
Zhang Z., Ng R., Man M.S.C., Li J., Wong W., Wong H.K., WANG D., Wong M., Tsang A., Yip K. and Sze C.W., Use of electroacupuncture to accelerate the antidepressant action of selective serotonin reuptake inhibitors: a single-blind, randomised, controlled study, Hong Kong Med J. . 2013, 19(Suppl 9): 12-6.


Researcher : Pan Y

List of Research Outputs

Pan Y., ZHAO L., Chen X., GU Y., Shen J. and Liu L.M., The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis, Asian Pacific Journal of Cancer Prevention. 2013, 14: 5761-5767.


Researcher : Rong J

Project Title:The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy
Investigator(s):Rong J
Department:LKS Medical Faculty
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2006


Project Title:Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) for the resolution of neutrophil-induced myocardial injury
Investigator(s):Rong J, Lau ASY, Li XC, Tse HF, Xia Z
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2012


Project Title:Regulation of neutrophil survival and migration in ischemic stroke by Chinese medicines Radix Astragali and Radix Paeoniae Rubrae via inducing leukotriene B4 12-hydroxydehydrogenase (LTB4DH)
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013
Completion Date:05/2014


Project Title:23rd Neuropharmacology Conference 2013, Sheraton San Diego Hotel and Marina, San Diego, 7 -8 November 2013; Pharmacological induction of arginase II by C-glucosylated isoflavonone puerarin suppresses nitric oxide-induced mitochondrial dysfunction in differentiated neuronal PC12 cells
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2013
Completion Date:11/2013


Project Title:Biological characterization of botanical non-steroidal progesterone receptor modulator puerarin for potentiating nerve growth factor (NGF)-induced neuritogenesis
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

CHENG Y., YANG C., ZHAO J. and Rong J., Purification of Z-Ligustilide by AgNO3-Impregnated Silica Gel, 硝酸银改性硅胶柱色谱法纯化川芎精油中的藁本内酯, Chinese Journal of Modern Applied Pharmacy. 中国现代应用药学, 2014, 31 (5): 552-555.
Cui W., Zhang Z.J., Hu S.Q., Mak S.H., Xu D.P., Choi C.L., Wang Y.Q., Tsim W.K., Lee M.Y., Rong J. and Han Y.F., Sunitinib Produces Neuroprotective Effect Via Inhibiting Nitric Oxide Overproduction, CNS Neurosci Ther. 2014, 20(3): 244-252.
YANG C., ZHAO J., CHENG Y., Li X.C. and Rong J., Bioactivity-guided fractionation identifies amygdalin as a potent neurotrophic agent from herbal medicine semen persicae extract, Biomed Research International. 2014, 2014: 306857-306867.
YANG C., ZHAO J., Pei W.J., Zheng X.H. and Rong J., Biochemical mechanisms of bornyl caffeate induced cytotoxicity in rat pheochromocytoma PC12 cells, Chem Biol Interact. 2014, 204.
YANG C., Pei W.J., ZHAO J., CHENG Y., Zheng X.H. and Rong J., Bornyl caffeate induces apoptosis in human breast cancer MCF-7 cells via the ROS- and JNK-mediated pathways, Acta Pharmacol Sin.. 2014, 35(1): 113-23.
YANG C., CHENG Y., ZHAO J. and Rong J., Research progress on the pharmacological activities of dihydroflavones, 二氢黄酮的药理活性研究进展, International Journal of Traditional Chinese Medicine . 国际中医中药杂志, 2014, 4: 370-375.
ZHAO J., Han Y.F. and Rong J., Neurotrophic and Cytoprotective Action of Puerarin in PC12 Cells via Sequentially Activating ERK1/2 Pathway and Inducing HO-1 Expression, 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria, August 27 - 29, 2013.
ZHAO J., Lau W.Y. and Rong J., Pharmacological induction of arginase II by C-glucosylated isoflavonone puerarin suppresses nitric oxide-induced mitochondrial dysfunction in differentiated neuronal PC12 cells, 23rd Neuropharmacology Conference 2013, Sheraton San Diego Hotel and Marina, San Diego, 7 -8 November 2013.


Researcher : SUN Y

List of Research Outputs

SUN Y., Liu P., JIA L., He Y., Wang Z., WANG N. and Chen J., Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: a cross-sectional survey, Journal of translational medicine. 2014.


Researcher : Shen J

Project Title:Biochemical Society Meeting 679 University of Essex UK - Stress, Signalling and Control Reactive Oxygen Species Mediate Intracellular Cholesterol Accumulation via Modulating Caveolin-1 Pathway in Chinese Hamster Ovary Cells
Investigator(s):Shen J
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2003


Project Title:Elucidating caveolin-1 as a negative modulating protein for proliferation of neural stem/progenitor cells and neural differentiation in post-ischemic brain
Investigator(s):Shen J, Chung SK, So KF
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2010


Project Title:Molecular regulations of reactive nitrogen species inhibitors for preventing thrombolysis-induced blood brain barrier disruption and hemorrhagic transformation in experimental cererbal ischemia-reperfersion models
Investigator(s):Shen J, Cheung RTF, Chung SK, Siu DCW, Yang D
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating proliferation and neuronal differentiation of neural stem/progenitor cells under hypoxic and ischemic conditions
Investigator(s):Shen J, Yang D, So KF
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012
Completion Date:10/2013


Project Title:Using Ski as a molecular target for seeking active compounds from Qingyihuaji (QYHJ) formula for inhibiting pancreatic cancer stem cells
Investigator(s):Shen J, Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2012
Completion Date:01/2014


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating proliferation and neuronal differentiation of neural stem/progenitor cells under hypoxic and ischemic conditions
Investigator(s):Shen J, Chung SK, So KF, Yang D
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2012


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating neurogenesis under hypoxic and ischemic conditions
Investigator(s):Shen J, Yang D, Chen X
Department:School of Chinese Medicine
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2013


Project Title:Effects of endosomal adaptor protein for regulating cell fate decision during differentiation of neural stem/progenitor cells
Investigator(s):Shen J, So KF, Chung SK
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013
Completion Date:04/2014


Project Title:Elucidating effects of APPL2 on regulating proliferation and cell fate decision of neural stem/progenitor cells through activating Notch signaling pathway
Investigator(s):Shen J, So KF, Chung SK
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Gordon Conference on Oxygen Radicals ; NITRIC OXIDE/CAVEOLIN-1/MATRIX METALLOPROTEINASES SIGNALING CASCADES IS A CRUCIAL PATHWAY IN BLOOD BRAIN BARRIER DISRUPTION DURING CEREBRAL ISCHEMIA-REPERFUSION INJURY
Investigator(s):Shen J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:02/2014
Completion Date:02/2014


Project Title:Roles of Caveolin-1 in Regulating T lymphocytes Infiltration through Blood Brain Barrier in Pathological Process of Experimental Autoimmune Encephalomyelitis
Investigator(s):Shen J, Chan GCF, Wu W
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

CHEN H., Chen C., DENG R. and Shen J., Caveolin-1 phosphorylation plays an important role in inhibition of oxygen–/INS;glucose-deprivation-induced endothelial cell apoptosis via regulating STAT3 pathway, Journal of the Neurological Sciences. 2013, 333: e227-e228.
Chen X., CHEN H., Deng R. and Shen J., Pros and cons of current approaches for detecting peroxynitrite and their applications, Biomedical Journal. 2014, 37: 120-126.
Chen Y., WU H., Nie Y.C., Li P.B., Shen J. and So W.W., Mucoactive effects of naringin in lipoploysaccharide-induced acute lung injury mice and beagle dogs. , Environmental Toxicology and Pharmacology 2014 . 2014, 38(1): 279-287.
GU Y., Chen J. and Shen J., Herbal Medicines for Ischemic Stroke: Combating Inflammation as Therapeutic Targets, Journal of Neuroimmune Pharmacology 31. 2014, 9: 313-339.
Pan Y., ZHAO L., Chen X., GU Y., Shen J. and Liu L.M., The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis, Asian Pacific Journal of Cancer Prevention. 2013, 14: 5761-5767.
Shen J., . Chinese herbal medicine: A great source for drug discovery targeting neurogenesis and brain repair for post stroke treatment. Keynote speaker,, Natural Health Products Scientific Workshop, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada, May 29-30, 2014. 2014.
Shen J., . From Genomics to Stem Cell Biology: Applications of Multidiscipline Approaches for Understanding Therapeutic Principles of A Classic Chinese Medicinal Formula for Post-Stroke treatment. Invited speaker, Guanganmen Hospital, Chinese Academy of Chinese Medicine, July 26, 2013 . 2013.
Shen J., . From genomics to stem cell biology: Applications of multidiscipline approaches for understanding therapeutic principles of A classic Chinese medicinal formula for post-stroke treatment. , The 2nd Forum of Integrated Medicine for Neurological diseases, Beijing, October 12-13, 2013. . 2013.
Shen J. and GU Y., 1. Shen JG*, Gu Y. Insights into mechanisms of blood brain barrier permeability: Roles of free radicals, matrix metalloproteinases and caveolin-1. , Systems Biology of Oxidative Stress. (Eds. Ismail Laher), Springer 2014,. 2014, pp 2049-2067.
Shen J., Bioactivity guided drug discovery from Spatholobus suberectus targeting glycolysis for breast cancer treatment. Keynote speaker , 2013 International Symposium on Anticancer Drugs from Natural Products, RCAA, Seoul National University, August 22-23, 2013. 2013.
Shen J., Bioactivity guided drug discovery from Spatholobus suberectus targeting glycolysis for breast cancer treatment. Plenary speaker,, XI. International Ethnobotany Symposio, Antalya-TURKEY, November 2-5, 2013.
Shen J., Chinese herbal medicine: A drug candidate bank for targeting neural stem cells and promoting adult neurogenesis in stroke treatment. , 3rd International Neural Regeneration Symposium (INRS2013), Shenyang, China, October 9-11, 2013.
Shen J., Chinese herbal medicine: A great source for promoting adult neurogenesis in stroke treatment and drug discovery. Invited speaker, Appointment Ceremony of Guest Professorship and Mini-symposium, Jinan University, Guangzhou, China, October 29, 2013. 2013.
Shen J., Current Progress in Medical Imaging Diagnosis and Therapeutic Strategies for Stroke: Opportunities and Challenges for Chinese Medicine. Invited speaker, , National Lab Lectureship, Central China University of Science and Technology, Wuhan, Hubei, March 12, 2014. 2014.
Shen J., Diarylamine-Based Fluorogenic Probes for Detection of Peroxynitrite, WO2013113279 A1 , 2013.
Shen J., Dose-dependent Effects and Pharmacokinetics of Buyang Huanwu Decoction for Stroke Treatment: Exploring Therapeutic Model of Chinese Medicinal Formula., 973 State Key Project Rrogress Report and Symposium__Chinese Medicine Chapter, Beijing, March 21-22, 2014. 2014.
Shen J., Exploring a novel pharmacological and therapeutic model of Chinese herbal formula: A lessen from Buyang Huanwu Decoction. Invited speaker , Qishun Lecturship, Fujian Chinese Medical University, Fuzhou, China . 2014.
Shen J., Nitric Oxide/Caveolin-1/MMP pathway: A novel therapeutic strategy for drug discovery from herbal medicine targeting blood-brain-barrier disruption during cerebral Ischemia-reperfusion injury., International Conference for Microcirculation and the 13th Annual Conference of the Professional Committee for Microcirculaion, Chinese Association of Integrative Medicine. Beijing, China. September 6-8, 2013.
Shen J., Nitric oxide/caveolin-1/matrix metalloproteinases signaling cascades is a crucial pathway in blood brain disruption during cerebral ischemia-rperfusion injury , Gordon Research Conference for Oxygen Radicals, Ventura, CA, February 9-14, 2014 . 2014.
Shen J., Perspectives of Chinese herbal medicine for translational medicine and drug discovery targeting neural stem cells: A opportunity for stroke and neurodegenerative diseases. Keynote speaker , Open Ceremony for Standard Committee of Translational Medicine in Guangdong Integrative Medicine Society & 1th Translational Medicine Symposium, Guangzhou, China, December 14-15, 2013 . 2013.
Shen J., Perspectives of targeting neural stem cells for drug discovery to promoting neurogenesis in stroke treatment with Chinese herbal medicine. Invited speaker, National Key Lab Lectureship, Chinese Pharmaceutical University, Nanjing, China, November 14, 2013 . 2013.
Shen J., Reactive nitrogen species are critical targets for blood brain barrier integrity and brain repairs in cerebral ischemia and reperfusion injury. Plenary speaker, , Nitric Oxide, Cardiovascular Diseases and Health Symposium, Beijing, China, April 18, 2014. 2014.
Shen J., Targeting neural stem cells : A novel therapeutic strategy of Chinese medicinal formula for stroke treatment., Excellent Scholar Lectureship, The Second Chinese Medical Hospital in Guangdong Province, Guangzhou, China, March 29, 2014. . 2014.
Shen J., Chen X., CHEN X. and Deng R., Targeting neurogenesis: a promising therapeutic strategy for post-stroke treatment with Chinese herbal medicine, Integrative Medicine International. 2014, 1: 5-18.
Shen J., 中醫藥治療中風循證醫學临床評價現狀及中醫诊断治療研究的機遇與挑戰, 中醫藥學會聯合會中醫診斷學專業委員會成立大會暨第一次學術會議, 湖南長沙 June 20-22, 2014. 2014.
Wang Z., WANG N., Han S., Wang D., Mo S., Yu L., Huang H., Tsui K., Shen J. and Chen J., Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Growth And Neoangiogenesis Via Blocking Vegf/vegfr-2 Signaling Pathway, Plos One. Plos, 2013, 8: 14.
Xu M., Chen X., Gu Y., Peng T., Yang D., Chang R.C.C., So K.F., Liu K. and Shen J., Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury, J Ethnopharmacol. 2013, 150(1): 116-24.
Zhang E., Shen J. and So K.F., Chinese traditional medicine and adult neurogenesis in the hippocampus. , Journal of Traditional and Complementary Medicine . 2014, 4: 77-81.
仝小林 , Shen J., 王躍生 , 傅延齡 , 徐國良 , 連鳳梅 , 饒毅 , 餘日躍 , 劉安 , 宋軍 , 劉文科 , 陳欣燕 , 徐立鵬 , 趙錫艷 , 周強 and 趙林華 , 慢病方藥合理用量理論探討, 世界中醫藥. 2014, (1): 1-2,7.


Researcher : Sze CW

Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS, Zhang Y, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:12/2009


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2010


Project Title:Mechanistic study of a Steriodogenic Protein from Dioscorea opposite Thunb for cardiovascular protection in menopausal rat model
Investigator(s):Sze CWS, Tong Y, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012
Completion Date:10/2013


Project Title:Mechanistic study of iron metabolism in gonadal and extra-gonadal tissues during aging
Investigator(s):Sze CWS, Tong Y, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013


Project Title:Mechanistic study of CAM118, a Chinese Medicine Formula, as an adjuvant therapy for colon cancer and relieving chemotherapy-induced osteoporosis
Investigator(s):Sze CWS, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2014


List of Research Outputs

Chan Y.S., Zhang Y., Sze C.W. and Ng T.B., A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans, Journal of Enzyme Inhibition and Medicinal Chemistry. UK, 2013, 2013: 1475-6374.
Chu S.M.E., Sze C.W., Cheung H.P., Liu Q., Ng T.B. and Tong Y., An In Vitro and In Vivo Investigation of the Antimetastatic Effects of a Chinese Medicinal Decoction, Erxian Decoction, on Human Ovarian Cancer Models, Integrative Cancer Therapies. SAGE Journals, 2013, 12: 336-346.
Lam Y., Sze C.W., Tong Y., Ng T.B., Shaw P.C. and Zhang Y., A review of the potential issues of pollution caused by the Mineral elements, Mercury, Lead and Arsenic, its possible impacts on the human beings and the suggested solutions, In: Y Lam, CW Sze, Tong Y, TB Ng, PC Shaw, YB Zhang*, Chinese Medicine. 2013, 3: 167-78.
Sze C.W., Lai Y.M., Zhang Y., Ng T.B., Tong Y., WONG K.L., CHEUNG H.P., LU J., ZHANG L. and LEIGH A.B., Novel Bioactive Protein Isolated from Chinese Yam for Menopause, The 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria. 2013.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof, US Patent and Trademark Office. US20130217626 A1, 2013.
WANG Z., WONG R...N...S..., Sze C.W., NG T...B..., TO W...S..., ZHANG W., LO K.C., YAU T... and Li L., Mechanistic Study of Circadian Rhythms of Tryptophan Hydroxylase and Serotonin Receptors Involved in Acupuncture-induced Analgesia, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.
ZHANG L., CHEUNG H.P., Lee C.K.F., Ng T.B., Zhang Y., Lao L. and Sze C.W., Proteomics Analysis of the Ovarian Tissues of Sprague-Dawley Rats of Different Ages to Identify Aging-Associated Changes, Ninth International Symposium on Healthy Aging “Aging with Confidence”, Hong Kong. 2014.
Zhang Z., Ng R., Man M.S.C., Li J., Wong W., Wong H.K., WANG D., Wong M., Tsang A., Yip K. and Sze C.W., Use of electroacupuncture to accelerate the antidepressant action of selective serotonin reuptake inhibitors: a single-blind, randomised, controlled study, Hong Kong Med J. . 2013, 19(Suppl 9): 12-6.
Zhong L., Tong Y., Tang G.W.K., Zhang Z., Choi W.K., Cheng K., Sze C.W., Wai K., Liu Q. and Yu X., A randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong perimenopausal women, Menopause . 2013, 20: 767-776.


Researcher : TAN HY

List of Research Outputs

TAN H.Y., Wang N., Tsao G.S.W., Zhang Z. and Feng Y., Suppression of Vascular Endothelial Growth Factor via Inactivation of Eukaryotic Elongation Factor 2 by Alkaloids in Coptidis rhizoma in Hepatocellular Carcinoma, Integrative Cancer Therapies. 2013.
Wang N., ZHU M., Wang X., TAN H.Y., Tsao G.S.W. and Feng Y., Berberine-induced tumor suppressor p53 up-regulation gets involved in the regulatory network of MIR-23a in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2014.


Researcher : Tong Y

Project Title:A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials
Investigator(s):Tong Y, Shen J, Zhong L, Diu CK
Department:School of Chinese Medicine
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:09/2009


Project Title:A pure chemical isolated from cortex phellodendri as a potential drug candidate for treating menopausal syndrome
Investigator(s):Tong Y, Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2011


List of Research Outputs

CHEUNG F., Wang X., Wang N., Yuen R.M.F., Zia T.C., Tong Y., Wong V.C.W. and Feng Y., Chinese Medicines as an Adjuvant Therapy for Unresectable Hepatocellular Carcinoma during Transarterial Chemoembolization: A Meta-Analysis of Randomized Controlled Trials, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2013, 2013:487919.: doi: 10.1155/2013/487919.
Chu S.M.E., Sze C.W., Cheung H.P., Liu Q., Ng T.B. and Tong Y., An In Vitro and In Vivo Investigation of the Antimetastatic Effects of a Chinese Medicinal Decoction, Erxian Decoction, on Human Ovarian Cancer Models, Integrative Cancer Therapies. SAGE Journals, 2013, 12: 336-346.
Lam Y., Sze C.W., Tong Y., Ng T.B., Shaw P.C. and Zhang Y., A review of the potential issues of pollution caused by the Mineral elements, Mercury, Lead and Arsenic, its possible impacts on the human beings and the suggested solutions, In: Y Lam, CW Sze, Tong Y, TB Ng, PC Shaw, YB Zhang*, Chinese Medicine. 2013, 3: 167-78.
Sze C.W., Lai Y.M., Zhang Y., Ng T.B., Tong Y., WONG K.L., CHEUNG H.P., LU J., ZHANG L. and LEIGH A.B., Novel Bioactive Protein Isolated from Chinese Yam for Menopause, The 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria. 2013.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof, US Patent and Trademark Office. US20130217626 A1, 2013.
Tong Y. and Chen H., An Implement of Outcome-based Approaches to Student Learning in Common Core Curriculum, 12th Meeting of The Consortium for Globalization of Chinese Medicine. 2013, 85.
Tong Y., Feng Y. and Chen H., Chinese Medicine Programme of the Continuing Education in HKU, 12th Meeting of The Consortium for Globalization of Chinese Medicine. 2013, 275.
Zhong L., Tong Y., Tang G.W.K., Zhang Z., Choi W.K., Cheng K., Sze C.W., Wai K., Liu Q. and Yu X., A randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong perimenopausal women, Menopause . 2013, 20: 767-776.


Researcher : WANG D

List of Research Outputs

Zhang Z., WANG D., Man M.S.C., Ng R., McAlonan G.M., Wong H.K., Wong W., Lee J. and Tan Q.R., Platelet 5-HT1A receptor correlates with major depressive disorder in drug-free patients, Progress in Neuro-Psychopharmacology & Biological Psychiatry. Elsevier, 2014, 53: 74-79.
Zhang Z., Ng R., Man M.S.C., Li J., Wong W., Wong H.K., WANG D., Wong M., Tsang A., Yip K. and Sze C.W., Use of electroacupuncture to accelerate the antidepressant action of selective serotonin reuptake inhibitors: a single-blind, randomised, controlled study, Hong Kong Med J. . 2013, 19(Suppl 9): 12-6.


Researcher : WANG N

List of Research Outputs

CHEUNG F., Wang X., Wang N., Yuen R.M.F., Zia T.C., Tong Y., Wong V.C.W. and Feng Y., Chinese Medicines as an Adjuvant Therapy for Unresectable Hepatocellular Carcinoma during Transarterial Chemoembolization: A Meta-Analysis of Randomized Controlled Trials, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2013, 2013:487919.: doi: 10.1155/2013/487919.
SUN Y., Liu P., JIA L., He Y., Wang Z., WANG N. and Chen J., Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: a cross-sectional survey, Journal of translational medicine. 2014.
TAN H.Y., Wang N., Tsao G.S.W., Zhang Z. and Feng Y., Suppression of Vascular Endothelial Growth Factor via Inactivation of Eukaryotic Elongation Factor 2 by Alkaloids in Coptidis rhizoma in Hepatocellular Carcinoma, Integrative Cancer Therapies. 2013.
Wang N. and Feng Y., A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma, Biochim Biophys Acta-Molecular Cell research. 2013, 1833(12):2890-2899.: doi: 10.1016/j.bbamcr.2013.07.018.
Wang N., Feng Y., ZHU M., Siu A.F.M., Ng K.M. and Che C.M., A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2013, 1833: 2890-2899.
Wang N., ZHU M., Wang X., TAN H.Y., Tsao G.S.W. and Feng Y., Berberine-induced tumor suppressor p53 up-regulation gets involved in the regulatory network of MIR-23a in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2014.
Wang N., Zhu M., Tsao G.S.W., Man K., Zhang Z. and Feng Y., MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma, Molecular Cancer. Elsevier, 2013, 12(1):119.: doi: 10.1186/1476-4598-12-119.
Wang Z., WANG N., Han S., Wang D., Mo S., Yu L., Huang H., Tsui K., Shen J. and Chen J., Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Growth And Neoangiogenesis Via Blocking Vegf/vegfr-2 Signaling Pathway, Plos One. Plos, 2013, 8: 14.


Researcher : WANG Z

List of Research Outputs

Cheng C., Wang Z. and Chen J., Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine, Evid Based Complement Alternat Med.. 2014.
Han S., Tang Q., Zheng F., Zhao S.Y., Wang Z. and Chen J., Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth., Molecular cancer. 2014.
Han S., Chen J., Wang Z., wu J., zheng F. and zhao S., Targeting EP4 by Curcumin through cross Talks of AMP-dependent Kinase Alpha and p38 Mitogen-activated Protein Kinase Signaling: The Role of PGC-1α and Sp1., Cell Signal.. 2013, 2566-2574.
Liang J., Chen J., Tan Z., Peng J., Zheng X., Nishiura K., Ng J., Wang Z., Wang D., Chen Z. and Liu L., Extracts of medicinal herb Sanguisorba officinalis inhibit the entry of human immunodeficiency virus type one. , JFDA. 2013, 21(4): 52-58.
SUN Y., Liu P., JIA L., He Y., Wang Z., WANG N. and Chen J., Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: a cross-sectional survey, Journal of translational medicine. 2014.
WANG Z., WONG R...N...S..., Sze C.W., NG T...B..., TO W...S..., ZHANG W., LO K.C., YAU T... and Li L., Mechanistic Study of Circadian Rhythms of Tryptophan Hydroxylase and Serotonin Receptors Involved in Acupuncture-induced Analgesia, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.
Wang Z., WANG N., Han S., Wang D., Mo S., Yu L., Huang H., Tsui K., Shen J. and Chen J., Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Growth And Neoangiogenesis Via Blocking Vegf/vegfr-2 Signaling Pathway, Plos One. Plos, 2013, 8: 14.
Zhou Y., Tang Q., Zhao S., Zhang F., Li L., Wu W., Wang Z. and Han S., Targeting signal transducer and activator of transcription 3 contributes to the solamargine-inhibited growth and -induced apoptosis of human lung cancer cells., Tumor Biology. 2014.


Researcher : WONG KL

List of Research Outputs

Sze C.W., Lai Y.M., Zhang Y., Ng T.B., Tong Y., WONG K.L., CHEUNG H.P., LU J., ZHANG L. and LEIGH A.B., Novel Bioactive Protein Isolated from Chinese Yam for Menopause, The 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria. 2013.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof, US Patent and Trademark Office. US20130217626 A1, 2013.


Researcher : WU H

List of Research Outputs

Chen Y., WU H., Nie Y.C., Li P.B., Shen J. and So W.W., Mucoactive effects of naringin in lipoploysaccharide-induced acute lung injury mice and beagle dogs. , Environmental Toxicology and Pharmacology 2014 . 2014, 38(1): 279-287.


Researcher : Wang L

List of Research Outputs

Wang L., Application Experience Of Xiaofeng Powder In Treatment Of Infantile Eczema, 消風散在治療嬰幼兒濕瘡中的應用體會, In: World Federation Of Chinese Medicine Societies, Specialty Committee of Dermatology, The Fourth Tcm Dermatology International Academic Conference Of the World Federation Of Chinese Medicine Societies. 世界中醫藥學會聯合會第四屆中醫皮膚科國際學術大會, 2013.


Researcher : Wang MN

Project Title:Establishment of Dual-Bioluminescent In Vivo Imaging of Autophagy in Orthotopical HCC-Implanted Mice Model To Examine the Anti-Tumor Effect of Chinese Medicine
Investigator(s):Wang N, Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:12th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM); The anti-metastatic effect of genipin, a natural product in Gardenia jasminoides Ellis on hepatocellular carcinoma and its underlying mechanism
Investigator(s):Wang N
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


List of Research Outputs



Researcher : Wang N

Project Title:Establishment of Dual-Bioluminescent In Vivo Imaging of Autophagy in Orthotopical HCC-Implanted Mice Model To Examine the Anti-Tumor Effect of Chinese Medicine
Investigator(s):Wang N, Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:12th Meeting of the Consortium for Globalization of Chinese Medicine (CGCM); The anti-metastatic effect of genipin, a natural product in Gardenia jasminoides Ellis on hepatocellular carcinoma and its underlying mechanism
Investigator(s):Wang N
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


List of Research Outputs

CHEUNG F., Wang X., Wang N., Yuen R.M.F., Zia T.C., Tong Y., Wong V.C.W. and Feng Y., Chinese Medicines as an Adjuvant Therapy for Unresectable Hepatocellular Carcinoma during Transarterial Chemoembolization: A Meta-Analysis of Randomized Controlled Trials, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2013, 2013:487919.: doi: 10.1155/2013/487919.
SUN Y., Liu P., JIA L., He Y., Wang Z., WANG N. and Chen J., Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: a cross-sectional survey, Journal of translational medicine. 2014.
TAN H.Y., Wang N., Tsao G.S.W., Zhang Z. and Feng Y., Suppression of Vascular Endothelial Growth Factor via Inactivation of Eukaryotic Elongation Factor 2 by Alkaloids in Coptidis rhizoma in Hepatocellular Carcinoma, Integrative Cancer Therapies. 2013.
Wang N. and Feng Y., A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma, Biochim Biophys Acta-Molecular Cell research. 2013, 1833(12):2890-2899.: doi: 10.1016/j.bbamcr.2013.07.018.
Wang N., Feng Y., ZHU M., Siu A.F.M., Ng K.M. and Che C.M., A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2013, 1833: 2890-2899.
Wang N., ZHU M., Wang X., TAN H.Y., Tsao G.S.W. and Feng Y., Berberine-induced tumor suppressor p53 up-regulation gets involved in the regulatory network of MIR-23a in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2014.
Wang N., Zhu M., Tsao G.S.W., Man K., Zhang Z. and Feng Y., MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma, Molecular Cancer. Elsevier, 2013, 12(1):119.: doi: 10.1186/1476-4598-12-119.
Wang Z., WANG N., Han S., Wang D., Mo S., Yu L., Huang H., Tsui K., Shen J. and Chen J., Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Growth And Neoangiogenesis Via Blocking Vegf/vegfr-2 Signaling Pathway, Plos One. Plos, 2013, 8: 14.


Researcher : Wang X

List of Research Outputs

CHEUNG F., Wang X., Wang N., Yuen R.M.F., Zia T.C., Tong Y., Wong V.C.W. and Feng Y., Chinese Medicines as an Adjuvant Therapy for Unresectable Hepatocellular Carcinoma during Transarterial Chemoembolization: A Meta-Analysis of Randomized Controlled Trials, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2013, 2013:487919.: doi: 10.1155/2013/487919.
Wang N., ZHU M., Wang X., TAN H.Y., Tsao G.S.W. and Feng Y., Berberine-induced tumor suppressor p53 up-regulation gets involved in the regulatory network of MIR-23a in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2014.


Researcher : Wang Z

Project Title:Elucidating Caveolin-1 as a negative regulator for breast cancer glycolysis activity via activating the c-Myc induced energy metabolism reprogramming
Investigator(s):Wang Z, Chen J, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:International Congress on Naturopathic Medicine; Bioactivity-guided Identification and Cell Signaling Technology to Delineate the Lactate Dehydrogenase A Inhibition Effects of Spatholobus suberectus on Breast Cancer
Investigator(s):Wang Z
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2013
Completion Date:07/2013


Project Title:Exploration of dietary compound isoliquiritigenin in chemosensitizing breast cancer stem cells by targeting aberrant β–catenin signalling
Investigator(s):Wang Z, Chen J, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:11/2013


List of Research Outputs

Cheng C., Wang Z. and Chen J., Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine, Evid Based Complement Alternat Med.. 2014.
Han S., Tang Q., Zheng F., Zhao S.Y., Wang Z. and Chen J., Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth., Molecular cancer. 2014.
Han S., Chen J., Wang Z., wu J., zheng F. and zhao S., Targeting EP4 by Curcumin through cross Talks of AMP-dependent Kinase Alpha and p38 Mitogen-activated Protein Kinase Signaling: The Role of PGC-1α and Sp1., Cell Signal.. 2013, 2566-2574.
Liang J., Chen J., Tan Z., Peng J., Zheng X., Nishiura K., Ng J., Wang Z., Wang D., Chen Z. and Liu L., Extracts of medicinal herb Sanguisorba officinalis inhibit the entry of human immunodeficiency virus type one. , JFDA. 2013, 21(4): 52-58.
SUN Y., Liu P., JIA L., He Y., Wang Z., WANG N. and Chen J., Characteristics of TCM constitutions of adult Chinese women in Hong Kong and identification of related influencing factors: a cross-sectional survey, Journal of translational medicine. 2014.
WANG Z., WONG R...N...S..., Sze C.W., NG T...B..., TO W...S..., ZHANG W., LO K.C., YAU T... and Li L., Mechanistic Study of Circadian Rhythms of Tryptophan Hydroxylase and Serotonin Receptors Involved in Acupuncture-induced Analgesia, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.
Wang Z., WANG N., Han S., Wang D., Mo S., Yu L., Huang H., Tsui K., Shen J. and Chen J., Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Growth And Neoangiogenesis Via Blocking Vegf/vegfr-2 Signaling Pathway, Plos One. Plos, 2013, 8: 14.
Zhou Y., Tang Q., Zhao S., Zhang F., Li L., Wu W., Wang Z. and Han S., Targeting signal transducer and activator of transcription 3 contributes to the solamargine-inhibited growth and -induced apoptosis of human lung cancer cells., Tumor Biology. 2014.


Researcher : Wong HK

List of Research Outputs

Zhang Z., WANG D., Man M.S.C., Ng R., McAlonan G.M., Wong H.K., Wong W., Lee J. and Tan Q.R., Platelet 5-HT1A receptor correlates with major depressive disorder in drug-free patients, Progress in Neuro-Psychopharmacology & Biological Psychiatry. Elsevier, 2014, 53: 74-79.
Zhang Z., Ng R., Man M.S.C., Li J., Wong W., Wong H.K., WANG D., Wong M., Tsang A., Yip K. and Sze C.W., Use of electroacupuncture to accelerate the antidepressant action of selective serotonin reuptake inhibitors: a single-blind, randomised, controlled study, Hong Kong Med J. . 2013, 19(Suppl 9): 12-6.


Researcher : Wong VCW

List of Research Outputs

CHEUNG F., Wang X., Wang N., Yuen R.M.F., Zia T.C., Tong Y., Wong V.C.W. and Feng Y., Chinese Medicines as an Adjuvant Therapy for Unresectable Hepatocellular Carcinoma during Transarterial Chemoembolization: A Meta-Analysis of Randomized Controlled Trials, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2013, 2013:487919.: doi: 10.1155/2013/487919.


Researcher : Wu J

Project Title:Anti-cystic hyperplasia of breast herbal medicine research
Investigator(s):Wu J, Chow LWC
Department:School of Chinese Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:05/2001


Project Title:Anti-prostatomegaly herbal medicine research
Investigator(s):Wu J, Leung SYL
Department:School of Chinese Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:06/2001




Researcher : Xu M

List of Research Outputs

Xu M., Chen X., Gu Y., Peng T., Yang D., Chang R.C.C., So K.F., Liu K. and Shen J., Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury, J Ethnopharmacol. 2013, 150(1): 116-24.


Researcher : YANG C

List of Research Outputs

CHENG Y., YANG C., ZHAO J. and Rong J., Purification of Z-Ligustilide by AgNO3-Impregnated Silica Gel, 硝酸银改性硅胶柱色谱法纯化川芎精油中的藁本内酯, Chinese Journal of Modern Applied Pharmacy. 中国现代应用药学, 2014, 31 (5): 552-555.
YANG C., ZHAO J., CHENG Y., Li X.C. and Rong J., Bioactivity-guided fractionation identifies amygdalin as a potent neurotrophic agent from herbal medicine semen persicae extract, Biomed Research International. 2014, 2014: 306857-306867.
YANG C., ZHAO J., Pei W.J., Zheng X.H. and Rong J., Biochemical mechanisms of bornyl caffeate induced cytotoxicity in rat pheochromocytoma PC12 cells, Chem Biol Interact. 2014, 204.
YANG C., Pei W.J., ZHAO J., CHENG Y., Zheng X.H. and Rong J., Bornyl caffeate induces apoptosis in human breast cancer MCF-7 cells via the ROS- and JNK-mediated pathways, Acta Pharmacol Sin.. 2014, 35(1): 113-23.
YANG C., CHENG Y., ZHAO J. and Rong J., Research progress on the pharmacological activities of dihydroflavones, 二氢黄酮的药理活性研究进展, International Journal of Traditional Chinese Medicine . 国际中医中药杂志, 2014, 4: 370-375.


Researcher : Yeung WF

Project Title:A Systemic Review on the Effectiveness of Chinese Herbal Medicine for Depression
Investigator(s):Yeung WF, Chung KF
Department:Psychiatry
Source(s) of Funding:Hospital Authority - General Award
Start Date:02/2013


Project Title:Use of Complementary and Alternative Medicine for Insomnia in Hong Kong
Investigator(s):Yeung WF, Chung KF
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:08/2014


Project Title:12th Meeting of the Consortium for Globalization of Chinese Medicine ; Utilization of Traditional Chinese Medicine and Other Complementary and Alternative Medicine for Improving Sleep in Hong Kong: A Telephone Survey
Investigator(s):Yeung WF
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


List of Research Outputs

Chung K.F., Yeung W.F., Yu Y.M., Yung K.P., Zhang S.P., Wong M.T., Lee W.K. and Chan L.W., Acupuncture for residual insomnia associated with major depressive disorder: a placebo- and sham-controlled, subject- and assessor-blind, randomized trial, Journal of Clinical Psychiatry . 2014, accepted..


Researcher : Yiu YM

List of Research Outputs

Yiu Y.M. and Chen F.H., 針灸治療非酒精性脂肪性肝病的臨床研究進展, Hong Kong Journal Of Traditional Chinese Medicine. 香港中醫雜志, 香港, 2014, 9(1): 83-84.
Yiu Y.M. and U W.S., Research on the Life Events of Patients with Eczema and the Proposal of Corresponding Acupuncture Treatment, 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). 2013.
Yiu Y.M. and Luo W.J., 中藥熱敷治療退行性膝骨關節炎的臨床觀察, 香港中醫雜志, 香港, 香港中醫雜志, 2013, 8(3): 25-26.


Researcher : Yu X

Project Title:Anti-angiogenic activity of Erxian Decoction, a traditional Chinese herbal formula, in zebrafish and HUVECs
Investigator(s):Yu X, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2012
Completion Date:08/2013


List of Research Outputs

Zhong L., Tong Y., Tang G.W.K., Zhang Z., Choi W.K., Cheng K., Sze C.W., Wai K., Liu Q. and Yu X., A randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong perimenopausal women, Menopause . 2013, 20: 767-776.


Researcher : Yum TP

List of Research Outputs

Yum T.P., LO K.C. and Li L., Review of the Impact of Acupuncture on Physiological Functions of Middle-distance and Long-distance Runners, 6th Taipei Traditional Chinese Medicine International Forum 2013. Taipei, 2014.
Yum T.P. and Li L., The Experimental Study Progress of Acupuncture on Rhythm, 2013 Chinese National Conference on Chronabiology. Nanchang, China, 2013.
ZHU L., Yum T.P., LO K.C. and Li L., Wrist-ankle Acupuncture for the Treatment of Pain Symptoms: A Systematic Review and Meta-analysis, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.


Researcher : ZHANG L

List of Research Outputs

Sze C.W., Lai Y.M., Zhang Y., Ng T.B., Tong Y., WONG K.L., CHEUNG H.P., LU J., ZHANG L. and LEIGH A.B., Novel Bioactive Protein Isolated from Chinese Yam for Menopause, The 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria. 2013.
ZHANG L., CHEUNG H.P., Lee C.K.F., Ng T.B., Zhang Y., Lao L. and Sze C.W., Proteomics Analysis of the Ovarian Tissues of Sprague-Dawley Rats of Different Ages to Identify Aging-Associated Changes, Ninth International Symposium on Healthy Aging “Aging with Confidence”, Hong Kong. 2014.


Researcher : ZHANG W

List of Research Outputs

WANG Z., WONG R...N...S..., Sze C.W., NG T...B..., TO W...S..., ZHANG W., LO K.C., YAU T... and Li L., Mechanistic Study of Circadian Rhythms of Tryptophan Hydroxylase and Serotonin Receptors Involved in Acupuncture-induced Analgesia, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.
ZHU L., LO K.C., Li L. and ZHANG W., The Clinical Research Progress of Tian Jiu Therapy for Infantile Bronchial Asthma, Hunan Journal of Traditional Chinese Medicine. 2013, 29(12): 159-160.


Researcher : ZHAO J

List of Research Outputs

CHENG Y., YANG C., ZHAO J. and Rong J., Purification of Z-Ligustilide by AgNO3-Impregnated Silica Gel, 硝酸银改性硅胶柱色谱法纯化川芎精油中的藁本内酯, Chinese Journal of Modern Applied Pharmacy. 中国现代应用药学, 2014, 31 (5): 552-555.
YANG C., ZHAO J., CHENG Y., Li X.C. and Rong J., Bioactivity-guided fractionation identifies amygdalin as a potent neurotrophic agent from herbal medicine semen persicae extract, Biomed Research International. 2014, 2014: 306857-306867.
YANG C., ZHAO J., Pei W.J., Zheng X.H. and Rong J., Biochemical mechanisms of bornyl caffeate induced cytotoxicity in rat pheochromocytoma PC12 cells, Chem Biol Interact. 2014, 204.
YANG C., Pei W.J., ZHAO J., CHENG Y., Zheng X.H. and Rong J., Bornyl caffeate induces apoptosis in human breast cancer MCF-7 cells via the ROS- and JNK-mediated pathways, Acta Pharmacol Sin.. 2014, 35(1): 113-23.
YANG C., CHENG Y., ZHAO J. and Rong J., Research progress on the pharmacological activities of dihydroflavones, 二氢黄酮的药理活性研究进展, International Journal of Traditional Chinese Medicine . 国际中医中药杂志, 2014, 4: 370-375.
ZHAO J., Han Y.F. and Rong J., Neurotrophic and Cytoprotective Action of Puerarin in PC12 Cells via Sequentially Activating ERK1/2 Pathway and Inducing HO-1 Expression, 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria, August 27 - 29, 2013.
ZHAO J., Lau W.Y. and Rong J., Pharmacological induction of arginase II by C-glucosylated isoflavonone puerarin suppresses nitric oxide-induced mitochondrial dysfunction in differentiated neuronal PC12 cells, 23rd Neuropharmacology Conference 2013, Sheraton San Diego Hotel and Marina, San Diego, 7 -8 November 2013.


Researcher : ZHAO L

List of Research Outputs

Pan Y., ZHAO L., Chen X., GU Y., Shen J. and Liu L.M., The XRCC1 Arg399Gln Genetic Polymorphism Contributes to Hepatocellular Carcinoma Susceptibility: An Updated Meta-analysis, Asian Pacific Journal of Cancer Prevention. 2013, 14: 5761-5767.


Researcher : ZHU L

List of Research Outputs

ZHU L. and Li L., Different View on the Function of Gallbladder, Asia-Pacific Traditional Medicine. 2013, 9(8): 60-61.
ZHU L., LO K.C., Li L. and ZHANG W., The Clinical Research Progress of Tian Jiu Therapy for Infantile Bronchial Asthma, Hunan Journal of Traditional Chinese Medicine. 2013, 29(12): 159-160.
ZHU L., Yum T.P., LO K.C. and Li L., Wrist-ankle Acupuncture for the Treatment of Pain Symptoms: A Systematic Review and Meta-analysis, The 12th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Graz, Austria, 2013.


Researcher : ZHU M

List of Research Outputs

Wang N., Feng Y., ZHU M., Siu A.F.M., Ng K.M. and Che C.M., A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2013, 1833: 2890-2899.
Wang N., ZHU M., Wang X., TAN H.Y., Tsao G.S.W. and Feng Y., Berberine-induced tumor suppressor p53 up-regulation gets involved in the regulatory network of MIR-23a in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2014.
Wang N., Zhu M., Tsao G.S.W., Man K., Zhang Z. and Feng Y., MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma, Molecular Cancer. Elsevier, 2013, 12(1):119.: doi: 10.1186/1476-4598-12-119.


Researcher : Zhang E

List of Research Outputs

Zhang E., Shen J. and So K.F., Chinese traditional medicine and adult neurogenesis in the hippocampus. , Journal of Traditional and Complementary Medicine . 2014, 4: 77-81.


Researcher : Zhang Y

Project Title:Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation
Investigator(s):Zhang Y, Sze CWS, Tong Y, Ho JCM, Tang SCW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:05/2012
Completion Date:11/2013


Project Title:Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation
Investigator(s):Zhang Y, Sze CWS, Tong Y, Ho JCM, Tang SCW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:05/2012
Completion Date:11/2013


Project Title:Investigation of Therapeutic Efficacy and Mechanisms of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation (ITS/313/11)
Investigator(s):Zhang Y, Sze CWS, Tong Y, Ho JCM, Tang SCW
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:05/2012
Completion Date:11/2013


Project Title:QSAR and Transport Mechanism Studies of Chrysotoxin, a Novel Nuroprotective Compound
Investigator(s):Zhang Y, Tong Y, Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012
Completion Date:06/2014


Project Title:the 3rd Annual Conference and EXPO of AnalytiX-2014; DNA Microarray for Authentication of Medicinal Dendrobium Species
Investigator(s):Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2014


Project Title:Evidencing effect of RHY in regulation of aquaporin-9 expression from damaged astrocytes closely associated with Alzheimer’s disease
Investigator(s):Zhang Y, Sze CWS, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Chan Y.S., Zhang Y., Sze C.W. and Ng T.B., A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans, Journal of Enzyme Inhibition and Medicinal Chemistry. UK, 2013, 2013: 1475-6374.
Chung W.Y. and Zhang Y., 中藥石斛研究進展., In: Chung Wing Yan, Zhang Yanbo., Traditional Chinese Medicine Today (Hong Kong).. 2013, 3: 19-20.
Lam Y., Sze C.W., Tong Y., Ng T.B., Shaw P.C. and Zhang Y., A review of the potential issues of pollution caused by the Mineral elements, Mercury, Lead and Arsenic, its possible impacts on the human beings and the suggested solutions, In: Y Lam, CW Sze, Tong Y, TB Ng, PC Shaw, YB Zhang*, Chinese Medicine. 2013, 3: 167-78.
Sze C.W., Lai Y.M., Zhang Y., Ng T.B., Tong Y., WONG K.L., CHEUNG H.P., LU J., ZHANG L. and LEIGH A.B., Novel Bioactive Protein Isolated from Chinese Yam for Menopause, The 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Graz, Austria. 2013.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof, US Patent and Trademark Office. US20130217626 A1, 2013.
ZHANG L., CHEUNG H.P., Lee C.K.F., Ng T.B., Zhang Y., Lao L. and Sze C.W., Proteomics Analysis of the Ovarian Tissues of Sprague-Dawley Rats of Different Ages to Identify Aging-Associated Changes, Ninth International Symposium on Healthy Aging “Aging with Confidence”, Hong Kong. 2014.


Researcher : Zhang Z

Project Title:The Establishment of Neurobehavioral Experiments into the Acupuncture Course (BCHM3003, 針灸學) of Undergraduate Chinese Medicine Programs
Investigator(s):Zhang Z, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:07/2007


Project Title:The development of a clinical-case search system to introduce case-study learning mode into Chinese medical curricula
Investigator(s):Zhang Z, Wong HK
Department:School of Chinese Medicine
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:09/2008


Project Title:The identification of central neural network for antidepressant effects of dense cranial electroacupuncture stimulation - a positron emission topographic (PET) study
Investigator(s):Zhang Z, Chung KF, Cowling BJ, Law ACK, Wong CS
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:The herbal medicine Peony-Glycyrrhiza Decoction (PGD) as an adjunctive therapy to treat antipsychotic-induced hyperprolactinemia in female patients with schizophrenia: a double-blind, randomized, placebo-controlled study
Investigator(s):Zhang Z, Chen EYH
Department:School of Chinese Medicine
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:02/2012


Project Title:Does concomitant use with Chinese medicines alter pharmacokinetic and toxicological profiles of antipsychotic drugs in experimental rats? Implication for herb-drug interactions
Investigator(s):Zhang Z, Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013


Project Title:The identification of psychopharmacological mechanisms of glycyrrhetinic acid in reducing antipsychotic-induced hyperprolactinemia
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013
Completion Date:04/2014


Project Title:The 12th Annual Meeting of Consortium for Globalization of Chinese Medicine (CGCM); A 6-week randomized controlled trial with 4-week follow-up of acupuncture combined with paroxetine in patients with major depressive disorder
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


Project Title:The identification of psychopharmacological mechanisms of glycyrrhetinic acid in reducing antipsychotic-induced hyperprolactinemia
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Acupuncture prevents chemobrain in patients with breast cancer: is it associated with the protection against cytokine production, epigenetic modification and microstructural changes of the brain?
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


Project Title:A novel therapeutic equipement called Acupoint-based Cranial Electromechanical Stimulator (ACEMS) for stress-associated symptoms
Investigator(s):Zhang Z, Hu Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2014


List of Research Outputs

Chen H., Ma C.H., Cao K., Ho J.C.M., Ziea E., Wang V.T. and Zhang Z., A Systematic Review and Meta-Analysis of Herbal Medicine on Chronic Obstructive Pulmonary Diseases, Evidence-Based Complementary and Alternative Medicine. 2014, 2014: 925069.
Chen H., Li S., Cho W. and Zhang Z., The role of acupoint stimulation as an adjunct therapy for lung cancer: a systematic review and meta-analysis, BMC Complement Altern Med. 2013, 13: 362-376.
Cheong K., Zhang J., Huang Y. and Zhang Z., The Effectiveness of Acupuncture in Prevention and Treatment of Postoperative Nausea and Vomiting - A Systematic Review and Meta-Analysis, PLoS One.. 2013, 8(12): e82474.
Huang Y., Chen J.Q., Lai X.S., Tang C.Z., Yang J.J., Chen H., Wu J.X., Xiao H.L., Qu S.S., Zhang Y.D. and Zhang Z., Lateralisation of cerebral response to active acupuncture in patients with unilateral ischemic stroke – an fMRI study., Acupunct Med. 2013, 31: 290-296.
Lian W., Pan M., Zhou D. and Zhang Z., Effectiveness of acupuncture for palliative care in cancer patients: A systematic review, Chin J Integr Med. . 2013, 20(2): 136-147.
MA C.H., Lian L.W., Leung L.S., Wong V.T., Ziea E.T. and Zhang Z., Chinese herbal medicine for benign prostatic hyperplasia: systematic review and meta-analysis, Asian Journal of Andrology . 2013, 15: 471-482.
MA C.H., Lin W., Lui S., Cai X., Wong V., Ziea E. and Zhang Z., Efficacy and safety of Chinese herbal medicine for benign prostatic hyperplasia: systematic review of randomized controlled trials., Asian J Androl. . 2013, 15(4): 471-82.
TAN H.Y., Wang N., Tsao G.S.W., Zhang Z. and Feng Y., Suppression of Vascular Endothelial Growth Factor via Inactivation of Eukaryotic Elongation Factor 2 by Alkaloids in Coptidis rhizoma in Hepatocellular Carcinoma, Integrative Cancer Therapies. 2013.
Wang H., Zhang R., Qiao Y., Xue F., Nie H., Zhang Z., Wang Y., Peng Z. and Tan Q., Gastrodin ameliorates depression-like behaviors and up-regulates proliferation of hippocampal-derived neural stem cells in rats: Involvement of its anti-inflammatory action, Behavioural Brain Research. 2014, 266: 153-160.
Wang N., Zhu M., Tsao G.S.W., Man K., Zhang Z. and Feng Y., MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma, Molecular Cancer. Elsevier, 2013, 12(1):119.: doi: 10.1186/1476-4598-12-119.
Yeung W.F., Chen H., Chung K.F. and Zhang Z., Clinical trials of traditional Chinese medicine for insomnia: current status and future directions, World Journal of Sleep Medicine. 2014, 1: 54-58.
Zhang Z., WANG D., Man M.S.C., Ng R., McAlonan G.M., Wong H.K., Wong W., Lee J. and Tan Q.R., Platelet 5-HT1A receptor correlates with major depressive disorder in drug-free patients, Progress in Neuro-Psychopharmacology & Biological Psychiatry. Elsevier, 2014, 53: 74-79.
Zhang Z., Ng R., Man M.S.C., Li J., Wong W., Wong H.K., WANG D., Wong M., Tsang A., Yip K. and Sze C.W., Use of electroacupuncture to accelerate the antidepressant action of selective serotonin reuptake inhibitors: a single-blind, randomised, controlled study, Hong Kong Med J. . 2013, 19(Suppl 9): 12-6.
Zhong L., Tong Y., Tang G.W.K., Zhang Z., Choi W.K., Cheng K., Sze C.W., Wai K., Liu Q. and Yu X., A randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong perimenopausal women, Menopause . 2013, 20: 767-776.


Researcher : Zhong L

List of Research Outputs

Zhong L., Tong Y., Tang G.W.K., Zhang Z., Choi W.K., Cheng K., Sze C.W., Wai K., Liu Q. and Yu X., A randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong perimenopausal women, Menopause . 2013, 20: 767-776.


Researcher : Zhu M

List of Research Outputs

Wang N., Feng Y., ZHU M., Siu A.F.M., Ng K.M. and Che C.M., A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2013, 1833: 2890-2899.
Wang N., ZHU M., Wang X., TAN H.Y., Tsao G.S.W. and Feng Y., Berberine-induced tumor suppressor p53 up-regulation gets involved in the regulatory network of MIR-23a in hepatocellular carcinoma, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2014.
Wang N., Zhu M., Tsao G.S.W., Man K., Zhang Z. and Feng Y., MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma, Molecular Cancer. Elsevier, 2013, 12(1):119.: doi: 10.1186/1476-4598-12-119.


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