DEPT OF MEDICINE



Researcher : Au KW

List of Research Outputs

Yiu K.H., Wong A., Pu L., Chiang R., Sit K.Y., Chan D., Lee H.Y., Lam Y.M., Chen Y., Siu D.C.W., Lau C.P., Au K.W. and Tse H.F., Prognostic value of preoperative right ventricular geometry and tricuspid valve tethering area in patients undergoing tricuspid annuloplasty, Circulation. 2014, 129: 87-92.


Researcher : Au WY

List of Research Outputs

Ho J.C.M., Au W.Y., HAN L., Kwong Y.L. and Ip M.S.M., Effect of therapeutic arsenic exposure on pulmonary function, Respiratory medicine. 2013, 107(9): 1423-1430.


Researcher : Bow HYC

List of Research Outputs

Samartzis D., Bow H.Y.C., Karppinen J.I., Luk K.D.K., Cheung B.M.Y. and Cheung K.M.C., Family history of low back pain is a significant predictor of pain and disability between extreme stages of lumbar disc degeneration, World Forum for Spine Research - Intervertebral Disc—from Degeneration to Therapeutic Motion Preservation. Xi'An, China, 2014.
Samartzis D., Bow H.Y.C., Karppinen J.I., Luk K.D.K., Cheung B.M.Y. and Cheung K.M.C., Hypertension is independently associated with lumbar disc degeneration: a large-scale population-based study, World Forum for Spine Research - Intervertebral Disc—from Degeneration to Therapeutic Motion Preservation. Xi'An, China, 2014.
Yim R., Lee J., Bow H.Y.C., Meij B., Leung V.Y.L., Cheung K.M.C., Vavken P. and Samartzis D., The safety and efficacy of mesenchymal stem cells for prevention or regeneration of intervertebral disc degeneration: a systematic review and meta-analyses, World Forum for Spine Research - Intervertebral Disc—from Degeneration to Therapeutic Motion Preservation. Xi'An, China, 2014.


Researcher : Bu L

Project Title:Investigation of the relationship between ISL1+ and WT1+ heart progenitor cells in humans
Investigator(s):Bu L, Li RA
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


Project Title:Study of cardiomyopathy through genome editing in human pluripotent stem cells
Investigator(s):Bu L, Li RA
Department:Physiology
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:12/2014




Researcher : But YKD

List of Research Outputs

Leung W.K., Lo O.S.H., Liu K.S., Tong S.M., But Y.K.D., Lam F.Y., Hsu A.S.J., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., Detection of Colorectal Adenoma by Narrow Band Imaging (HQ190) vs. High-Definition White Light Colonoscopy: A Randomized Controlled Trial, Am J Gastroenterol. 2014, 109(6): 855-63.
Liu K.S., Hung I.F.N., Seto W.K.W., Tong S.M., Hsu A.S.J., Lam F.Y., But Y.K.D., Wong S.Y. and Leung W.K., Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial, Gut. 2013.
Liu K.S.H., Hung I.F.N., Seto W.K.W., But Y.K.D., Hsu A.S.J., Tong S.M., Chan K.H., Tan V.P.Y. and Leung W.K., Immune Responses to intramuscular or intradermal trivalent influenza vaccines in patients with inflammatory bowel disease: A randomized controlled trial, Asian Organization for Crohn's and Colitis. 2014.


Researcher : CHE H

List of Research Outputs

CHE H., Yue J., Tse H.F. and Li G.R., Functional TRPV and TRPM channels in human preadipocytes, Pflügers Archiv - European Journal of Physiology. 2014, 466: 947-959.
ZHANG Y., Yue J., CHE H., Sun H., Tse H.F. and Li G.R., BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells., J Cell Physiol. . 2013, 229(2): 202-212.
ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : CHEN B

List of Research Outputs

Cheng K.Y., Zhu W., CHEN B., Wang Y., Wu D., Sweeney G., WANG B., Lam K.S.L. and Xu A., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle, Diabetes. 2014, DB_140337: Epub ahead of print.


Researcher : Chan CYJ

List of Research Outputs

Chan C.Y.J., Assistant Editor, The Hong Kong Journal of Dermatology and Venereology. MEDCOM, 2013.
Chan C.Y.J., Yap Y.H.D. and Yeung C.K., Hydralazine-induced toxic epidermal necrolysis in a patient on continuous ambulatory peritoneal dialysis, Journal of Clinical Pharmacy and Therapeutics. 2014, 39: 322-324.
Chan C.Y.J., Hwang Y.Y.G. and Luk J.K.H., Mycosis fungoides in elderly adults--a diagnostic challenge., Journal of the American Geriatrics Society . Wiley Online Library, 2014, 62(4): 786-7.
Chan C.Y.J., Updates on Drug-Induced Skin Hypersensitivity Reactions, 2013 Joint Conference of Drug Safety Research Centres, Hong Kong, Oct 2013. 2013.
Chan C.Y.J., Updates on Severe Cutaneous Adverse Reactions (SCAR) - from treatment to prevention, Annual Scientific Meeting 2014; The Hong Kong Society of Dermatology and Venereology. 2014.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Efficacy of high-intensity focused ultrasonography for noninvasive body sculpting in Chinese patients., Lasers in Surgery and Medicine. Wiley Online Library, 2014, 46(4): 263-9.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Efficiacy of a High-Intensity Focused Ultrasound Device for Non-invasive Body Contouring, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Non-invasive Cryolipolysis for Fat Reduction in Flanks in Chinese with a Modified Applicator , 19th Medical research Conference; Department of Medicine; Li KA Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Safety and Efficacy Evaluation of a Combined Device Using Infrred Light and Bi-polar Radiofrequency and Sublative Radiofrequency Applicators, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., The Efficacy of a Microwave Device for Treating Hyperhidrosis in Chinese, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.


Researcher : Chan DTM

Project Title:Provision of HBVDNA assays for immunosuppressed HBsAg-positive kidney transplant recipients and patients with kidney diseases
Investigator(s):Chan DTM, Yung SSY
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/2010


Project Title:The role of hyaluronan and effect of 4-methylumbelliferone in tubulo-interstitial fibrosis in lupus nephritis
Investigator(s):Chan DTM, Yung SSY
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2012
Completion Date:04/2014


Project Title:The Role of Annexin II in the Regulation of Inflammation and Fibrosis in Lupus Nephritis
Investigator(s):Chan DTM, Yung SSY
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:The role of connective tissue growth factor in the pathogenesis of lupus nephritis
Investigator(s):Chan DTM, Yung SSY
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:ASN Kidney Week 2013; Human anti-dsDNA antibodies induce amplification loop of transforming growth factor-beta1, fibronectin and collagen type I in proximal renal tubular epithelial cells
Investigator(s):Chan DTM
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2013
Completion Date:11/2013


Project Title:The Role of CD44 in the Pathogenesis of Lupus Nephritis
Investigator(s):Chan DTM, Yung SSY
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Gut Microbiota Products in the Pathogenesis of Lupus Nephritis
Investigator(s):Chan DTM, Yung SSY, Yap YHD
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


Project Title:The role of hepatocyte growth factor in lupus nephritis
Investigator(s):Chan DTM, Yung SSY
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2014


List of Research Outputs

Ip K.M., Yung S.S.Y., Chan D.T.M., Tsao G.S.W. and Wong A.S.T., p70 S6 kinase is a regulator of ovarian cancer metastasis via crosstalk between P-cadherin-beta1-integrin signaling axes., The 20th Hong Kong International Cancer Congress. 2013.
Ip K.M., Yung S.S.Y., Chan D.T.M., Tsao G.S.W. and Wong A.S.T., p70 S6 kinase promotes a critical step in ovarian cancer metastasis by modulating tumor-mesothelial cell adhesion through P-cadherin-beta1-integrin crosstalk., The European Cancer Congress 2013.
LAM S.N., Yung S.S.Y., Chan D.T.M., Tsao G.S.W. and Wong A.S.T., MicroRNA-145, a p70 S6 kinase-activated microRNA, regulates N-cadherin expression and epithelial-mesenchymal transition, 17thECCO - 28thESMO - 32ndESTRO European Cancer Congress, Amsterdam, Netherlands. 2013.
Li Y., Huang C., Zhao M., Liang G., Xiao R., Yung S.S.Y., Chan D.T.M. and Lu Q., A possible role of HMGB1 in DNA demethylation in CD4+ T Cells from patients with systemic lupus erythematosus, Clin Dev Immunol. 2013, Epub.
Ma K.M.M., Zuo M.L., Yap Y.H.D., Mok M.M., Kwan L.P., Chan G.C., Siu D.C.W. and Chan D.T.M., Chronotropic incompetence, echocardiographic abnormalities and exercise intolerance in renal transplant recipients., Journal of Nephrology. 2014.
Ma M.K., Kwan L.P., Mok M.M., Yap Y.H.D., Tang C.S. and Chan D.T.M., Significant reduction of Tacrolimus trough level after conversion from twice daily Prograf to once daily Advagraf in Chinese renal transplant recipients with or without concomitant diltiazem treatment, Renal Failure. 2013, 35: 942-945.
Mok C.C., Yap Y.H.D., Navarra S.V., Liu Z.H., Zhao M.H., Lu L., Takeuchi T., Avihingsanon Y., Yu X.Q., Lapid E.A., Lugue-Lizardo L.R., Sumethkul V., Shen N., Chen S.L., Chan D.T.M. and the Asian Lupus Nephritis Network (ALNN) , Overview of lupus nephritis management guidelines and perspective from Asia, International Journal of Rheumatic Diseases. 2013, 16(6): 625-636.
Mok C.C., Yap Y.H.D., Navarra S.V., Liu Z.H., Zhao M.H., Lu L., Takeuchi T., Avihingsanon Y., Yu X.Q., Lapid E.A., Lugue-Lizardo L.R., Sumethkul V., Shen N., Chen S.L., Chan D.T.M. and Asian Lupus Nephritis Network (ALNN) .., Overview of lupus nephritis management guidelines and perspective from Asia, Nephrology. 2014, 19: 11-20.
Mok M.M., Ma M.K., Yap Y.H.D., Chan D.T.M. and Lam M.F., Secondary atypical mycobacterial infection after peritoneal catheter removal, International Wound Journal. 2014, n/a-n/a.
TSUN G.S., Shiu S.W.M., Wong Y., Yung S.S.Y., Chan D.T.M. and Tan K.C.B., Impact of serum amyloid A on cellular cholesterol efflux to serum in type 2 diabetes mellitus., Atherosclerosis.. 2013, 231: 405-10.
Tan K.C.B., TSUN G.S., Yung S.S.Y., Chau K.M., Shiu S.W.M. and Chan D.T.M., Cholesterol transport proteins and diabetic nephropathy., World Diabetes Congress in Melbourne, Australia.. 2013.
Yap Y.H.D. and Chan D.T.M., An overview of current and future treatment methods for lupus nephritis, Expert Opinion Orphan Drugs. 2014, 2: 169-179.
Yap Y.H.D., Choy C.B.Y., Mok M.M., Wong T.K. and Chan D.T.M., Burkholderia cepacia-an uncommon cause of exit-site infection in a peritoneal dialysis patient, Peritoneal Dialysis International. 2014, 34(4): 471-472.
Yap Y.H.D., Chan G.S., Chan K.W., Kwan L.P., Wong W.T., Lam M.F. and Chan D.T.M., Cortical necrosis in a kidney transplant recipient due to leptospirosis, Nephrology. 2014, 19: 257-258.
Yap Y.H.D. and Chan D.T.M., Effect of long-term tacrolimus treatment in patients with lupus nephritis, European Renal Association - European Dialysis and Transplantation Association (ERA-EDTA) 51st Congress. 2014.
Yap Y.H.D., Yung S.S.Y., Tang C.S., Seto W.K.W., Ma M.K., Mok M.M., Kwan L.P., Chan G.C., Choy B.Y., Yuen R.M.F. and Chan D.T.M., Entecavir Treatment in Kidney Transplant Recipients Infected with Hepatitis B, Clinical Transplantation. 2014.
Yap Y.H.D. and Chan D.T.M., Evolution of hepatitis B management in kidney transplantation, World Journal of Gastroenterology. 2014, 20(2): 468-474.
Yap Y.H.D., Yung S.S.Y., Ma M.K., Mok M.M., Kwan L.P., Chan G.C. and Chan D.T.M., Serum immunoglobulin G level in patients with lupus nephritis and the effect of treatment with corticosteroids and mycophenolate mofetil, Lupus. 2014.
Yap Y.H.D. and Chan D.T.M., Treatment of lupus nephritis: practical issues in Asian countries, International Journal of Rheumatology Diseases. 2014, Epub ahead of print.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Chan FHW

List of Research Outputs

Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Efficacy of trivalent seasonal influenza vaccination in reducing mortality and hospitalization in Chinese nursing home older adults, Journal of the American Medical Directors Association . 2013, 14: 889-894.
Chan T.C.I., Luk J.K.H., Chan F.H.W., Chu L.W. and Hung I.F.N., Factors Associated with Seasonal Influenza Vaccination in Chinese Nursing Home Older Adults , Journal of the American Medical Directors Association . 2013, 14(10): 772-774.
Chan T.C.I., Hung I.F.N., Chan K.H., Li P.Y., Li T.W., Luk J.K.H., Chu L.W. and Chan F.H.W., Immunogenicity and Safety of Intradermal Trivalent Influenza Vaccination in Nursing Home Older Adults: A Randomized Controlled Trial., Journal of American Medical Directors Association. 2014.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Inadequate Knowledge of Pneumococcal Vaccine of Nursing Home Healthcare Workers Affects the Pneumococcal Vaccination Uptake of Older Adults in Nursing Homes , Journal of the American Geriatrics Society . 2013, 61(8): 1429-1430.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Predictor of Recurrent Hospitalization in Older Adults?, Journal of the American Medical Directors Association . 2013, 14(9): 706-707.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Risk Factor of Mortality in Chinese Older Adults?, Journal of the American Geriatrics Society . 2013, 61(8): 1430-1432.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Prevalence of Influenza Vaccination and Associated Factors in Chinese Nursing Home Healthcare Workers, Journal of the American Geriatrics Society . 2013, 61(10): 1824-1827.
Chau P.H., Kwok T., Chan F.H.W., Hui E. and Woo J., Discrepancies in perceived needs in community-based supporting services between older people with cognitive impairment and their caregivers, Poster presented at International Alzheimer's Disease Conference 2014. Hong Kong, China, 6-7 June 2014.
Chau P.H., Kwok T., Chan F.H.W., Hui E. and Woo J., Outstanding Investigator Award, International Alzheimer's Disease Conference 2014. Hong Kong, China, 6-7 June 2014. 2014.
Ho A.H.Y., Luk J.K.H. and Chan F.H.W., Approaching the End-of-Life: A Systemic Discourse of Dignity and Dignified Care in Hong Kong. , 10th International Conference on Grief and Bereavement in Contemporary Society. . 2014.
Ho A.H.Y., Luk J.K.H., Chan F.H.W., Chan C.W.K., Kwok C.K.K., Ng W.C., Yuen J.H.L., Tam M.Y.J. and Chan C.L.W., Dignified Care in LTC Settings: A Systemic-Interpretive Framework for Community-Based End-of-Life Care Pathway in Hong Kong., Asia Pacific Regional Conference on End-of-Life and Palliative Care in Long Term Care Settings.. 2013.
Lee J.S.W., Auyeung T.W., Chau P.H., Hui E., Chan F.H.W., Chi I. and Woo J., Obesity can benefit survival - a 9-year prospective study in 1614 Chinese nursing home residents, Journal of the American Medical Directors Association. 2014.
Tam M.Y.J., Ho A.H.Y., Chan C.L.W., Luk J.K.H., Chan F.H.W. and Ng W.C., An Integrated Framework for Community-Based End-of-life care pathway in Hong Kong., 10th International Conference on Grief and Bereavement in Contemporary Society.. 2014.


Researcher : Chan HHL

Project Title:The role of epidermal cooling in improving the outcome of laser therapy in the treatment of Nevus of Ota
Investigator(s):Chan HHL, Lam LK
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2000


Project Title:The use of vascular lasers in the treatment of port wine stain in chinese
Investigator(s):Chan HHL, Wei WI
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:11/2001


List of Research Outputs

Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Efficacy of high-intensity focused ultrasonography for noninvasive body sculpting in Chinese patients., Lasers in Surgery and Medicine. Wiley Online Library, 2014, 46(4): 263-9.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Efficiacy of a High-Intensity Focused Ultrasound Device for Non-invasive Body Contouring, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Non-invasive Cryolipolysis for Fat Reduction in Flanks in Chinese with a Modified Applicator , 19th Medical research Conference; Department of Medicine; Li KA Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Safety and Efficacy Evaluation of a Combined Device Using Infrred Light and Bi-polar Radiofrequency and Sublative Radiofrequency Applicators, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., The Efficacy of a Microwave Device for Treating Hyperhidrosis in Chinese, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.


Researcher : Chan HWF

List of Research Outputs

Tam M.Y.J., Ho A.H.Y., Chan C.L.W., Luk J.K.H. and Chan H.W.F., Navigating the Last Journey: A Hong Kong EoL Pathway., ADEC 36th Annual Conference. 2014.


Researcher : Chan JCK

Project Title:Application of the APACHE II and III prognostic scoring methods in the 14-bed Intensive Care Unit at Queen Mary Hospital
Investigator(s):Chan JCK, Lam WK
Department:Medicine
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:07/1995




Researcher : Chan KH

Project Title:Clinical outcome of multiple sclerosis in Hong Kong Chinese
Investigator(s):Chan KH
Department:Medicine
Source(s) of Funding:Bayer Pharmaceuticals Ltd. - General Award
Start Date:01/2008


Project Title:Study of clinical and immunological characteristics of local multiple sclerosis patients
Investigator(s):Chan KH, Ho SL
Department:Medicine
Source(s) of Funding:Bayer Pharmaceuticals Ltd. - General Award
Start Date:03/2008


Project Title:The role of Interleukin-17 a nd Interleukin-23 and magnetic resonance findings during relapse of multiple sclerosis and neuromyelitis optica
Investigator(s):Chan KH, Ho WL
Department:Medicine
Source(s) of Funding:Bayer Pharmaceuticals Ltd. - General Award
Start Date:04/2009


Project Title:Study of potential neuroprotective role of adiponectin and APPL1 in beta-amyloid neurotoxicity
Investigator(s):Chan KH, Lam KSL, Xu A, Ho SL, Ho WL
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2010


Project Title:Study of immunopathogenesis of multiple sclerosis and neuromyelitis optica
Investigator(s):Chan KH, Ho WL
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:06/2011


List of Research Outputs

Chan K.H., Cellular Therapy for Multiple Sclerosis, Second Annual Scientific Meeting Of Hong Kong Multiple Sclerosis Society 2013.
Chan K.H., Lee R., Lee J.C.Y., Tse C.T.A., Pang S.Y.Y., Lau G.K.K., Teo K.C. and Ho W.L., Central nervous system inflammatory demyelinating disorders among Hong Kong Chinese, Journal of Neuroimmunology. 2013, 262: 100-105.
Chan K.H., Chairman of Organizing Committee of Second Annual Scientific Meeting of Hong Kong Multiple Sclerosis Society, Hong Kong Multiple Sclerosis Society. 2013.
Chan K.H., Chairmanship of Poster Session of 19th Medical Research Conference, Department of Medicine, HKU. 2014.
Chan K.H., Chairmanship, International Conference on Alzheimer's Disease 2014, Hong Kong University Alzheimer's Disease Research Network, LKS Faculty of Medicine & Faculty of Social Science, the University of Hong Kong. 2014.
Chan K.H., Diabetes Mellitus and Cognitive Dysfunction, Update on Diabetes Management. 2013.
Chan K.H., Immunopathogenesis of Multiple Sclerosis, 6th Autoimmunity Congress Asia (ACA 2013). 2013.
Chan K.H., Insulin Resistance And Alzheimer's Disease, Forum on SRT Neuroscience Funding Proposals. 2014.
Chan K.H., Member of Local Organizing Committee, 6th Autoimmunity Congress Asia (ACA 2013). 2013.
Chan K.H., PACTRIMS Joint Symposium on Multiple Sclerosis: Immunologial Basis of MS and NMO, 14th Asian & Oceanian Congress of Neurology (AOCN 2014), 2 - 5 March 2014. Macao, China, 2014.
Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.
Cheung K.W., Shek N.W.M. and Chan K.H., An unusual cause of postpartum collapse:undiagnosed myasthenia gravis, Journal of Obstetrics and Gynecology . 2013, 33(5): 528.
Guo Y., Chung S.K., Siu D.C.W., Kwan S.C., Ho W.L., Yeung P.K.K., Teo K.C. and Chan K.H., Endothelin-1 overexpression exacerbate experimental allergic encephalomyelitis, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong. 2014.
Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon S.F.K., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality, PLoS One. 2014, 9(2): e88283.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S., Hon S.F., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality., Plos One . 2014, 11:9(2): e882883.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon F.K.S., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with cancer are at increased risk of recurrent stroke and cardiovascular mortality, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chan Y.H., Teo K.C., Chan K.H., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases – Relationships and comparisons with vascular markers of atherosclerosis, Atherosclerosis. 2014, 235(1): 230-235.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang R.S., Teo K.C., Hon S.F., Chan K.H., Wat K.L., Cheung R.T., Li L.S., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lau G.K.K., Wong Y.K., Chang R.S.K., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, European Journal of Neurology. 2014, 21(2): 319-325.
Lee C.Y., Lam C.L.D., Chang S.K.R., Pang Y.Y., Chang C., Lau G.K.K., Teo K.C., Ho S.L., Cheung R.T.F. and Chan K.H., Prognosis and Crisis in Generalised Myasthenia Gravis among Hong Kong Chinese, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.
Qian W., Chan K.H., Kim M. and Mak H.K.F., Comparison of efficacy of diffusion kurtosis imaging in detection of occult brain damages in neuromyelitis optica and multiple sclerosis. , International Society of Magnetic Resonance in Medicine 23rd Annual Scientific Meeting and Exhibition, May 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drug resumption after antiplatelet-related intracerebral haemorrhage, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 40.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Siu D.C.W., Leung G.K.K., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drugs resumption after antiplatelet-related intracerebral haemorrhage in Chinese , 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelt drug resumption after antiplatelet-related intracerebral haemorrhage, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Best Free Paper Award (First Runner-up): Antiplatelet Drugs Resumption after Antiplatelet-related Intra-cerebral Haemorrhage, 14th Asian & Oceanian Congress of Neurology. 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intra-cerebral haemorrhage in Hong Kong, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intracerebral hemorrhage in Hong Kong Chinese, Neurological Research. 2014, 36: 143-149.


Researcher : Chan MMW

Project Title:A surveillance program of tuberculosis in old age homes in Hong Kong
Investigator(s):Chan MMW, Chu LW, Lam WK
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:11/2001


Project Title:A surveillance program of tuberculosis in old age homes in Hong Kong
Investigator(s):Chan MMW, Chu LW, Lam WK
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2004


List of Research Outputs

Mak J.C.W., Ho S.P., Ho A.S., Law B.K., Cheung A.H.K., Ho J.C.M., Ip M.S.M. and Chan M.M.W., Sustained elevation of systemic oxidative stress and inflammation in exacerbation and remission of asthma, ISRN Allergy. 2013, 561831.


Researcher : Chan MNY

List of Research Outputs

Shea Y.F., Chu L.W., Zhou L., Li W.M., Lin O.Y., Chan M.N.Y., Xu A., Wong L.C., Ho T.Y. and Liu K.W., Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Chinese Patients: A Pilot Study, American Journal of Alzheimer's Disease and Other Dementias. 2013, 28: 769-775.


Researcher : Chan PHM

List of Research Outputs

Alegria-Barrero E., Chan P.H.M., Foin N., Syrseloudis D., Tavazzi G., Price S., Lindsay A.C., Duncan A., Moat N. and Di Mario C., Concept of the central clip: when to use one or two MitraClips, EuroIntervention. 2014, 9: 1217-1224.
Alegria-Barrero E., Foin N., Lindsay A.C., Paulo M., Chan P.H.M., Syrseloudis D., Viceconte N., Martos R., Beatt K. and Di Mario C., Minerva Cardioangiologica, How to optimize the percutaneous treatment of bifurcated lesions: dedicated stents vs. provisional stenting. 2013, 61: 575-590.
Chan P.H.M., Alegria-Barrero E., Foin N., Paulo M., Lindsay A.C., Viceconte N. and Di Mario C., Extended use of the GuideLiner in complex coronary interventions, EuroIntervention. 2014.
Chan P.H.M., Hyponatremia - its meaning on Acute HF management, The 7th Asian Pacific Congress of Heart Failure and 23rd Annual Scientific Meeting of Indonesia Heart Association. 2014.
Chan P.H.M., Liu S., Tse H.F., Chow W.H., Jim M.H., Ho H.H. and Siu D.C.W., Long-term clinical outcomes of drug-eluting stents vs. bare-metal stents in Chinese geriatric patients, Journal of Geriatric Cardiology. 2013.
Chan P.H.M., Non-pharmacological therapy for stroke prevention in atrial fibrillation, Advances in Management MIMS Lecture Series: Stroke Prevention in Atrial Fibrillation. 2014.
Chan P.H.M., Stroke Risk Stratification for atrial fibrillation patients , Advances in Management MIMS Lecture Series: Stroke Prevention in Atrial Fibrillation. 2014.
Chan P.H.M., She H.L.H. and Cheung C.W.S., Usefulness of computed tomography myocardial perfusion imaging in guiding the management of coronary artery disease, ASCI 2014: The 8th Congress of Asian Society of Cardiovascular Imaging. 2014.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.
Lindsay A.C., Paulo M., Kilickesmez K., Tejeiro R., Alegria-Barrero E., Chan P.H.M., Foin N., Syrseloudis D. and Di Mario C., Predictors of stent strut malapposition in calcified vessels using frequency-domain optical coherence tomography, Journal of Invasive Cardiology. 2013, 25: 429-434.


Researcher : Chan SY

List of Research Outputs

Chan S.Y., Gill H., Hwang Y.Y.G., Sim J., Tse C.T.A., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Annals of Hematology. 2014, 93(3): 493-498.
Chu L.W., So J.C., Wong L.C., Luk J.K.H., Chiu P.K.C., Chan S.Y., Kwan S.M., Chau J., Hui E., Woo J. and McGhee S., Community end-of-life care among Chinese older adults living in nursing homes, Geriatrics & Gerontology International. 2014, 14(2): 273-84.


Researcher : Chan TCI

List of Research Outputs

Chan F.H., Chan T.C.I., Hung I.F.N., Luk J.K.H., Chu L.W., Ng W.C., Law T.C. and Cheng V.C.C., Early Identification of an Influenza Outbreak in a Nursing Home with High Vaccination Coverage Facilitates Implementation of Infection-Control Measures and Prevents Spreading of Influenza Infection, Journal of American Medical Directors Association. 2014, 15(4): 300-1.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Efficacy of trivalent seasonal influenza vaccination in reducing mortality and hospitalization in Chinese nursing home older adults, Journal of the American Medical Directors Association . 2013, 14: 889-894.
Chan T.C.I., Luk J.K.H., Chan F.H.W., Chu L.W. and Hung I.F.N., Factors Associated with Seasonal Influenza Vaccination in Chinese Nursing Home Older Adults , Journal of the American Medical Directors Association . 2013, 14(10): 772-774.
Chan T.C.I., Hung I.F.N., Chan K.H., Li P.Y., Li T.W., Luk J.K.H., Chu L.W. and Chan F.H.W., Immunogenicity and Safety of Intradermal Trivalent Influenza Vaccination in Nursing Home Older Adults: A Randomized Controlled Trial., Journal of American Medical Directors Association. 2014.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Inadequate Knowledge of Pneumococcal Vaccine of Nursing Home Healthcare Workers Affects the Pneumococcal Vaccination Uptake of Older Adults in Nursing Homes , Journal of the American Geriatrics Society . 2013, 61(8): 1429-1430.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Predictor of Recurrent Hospitalization in Older Adults?, Journal of the American Medical Directors Association . 2013, 14(9): 706-707.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Risk Factor of Mortality in Chinese Older Adults?, Journal of the American Geriatrics Society . 2013, 61(8): 1430-1432.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Prevalence of Influenza Vaccination and Associated Factors in Chinese Nursing Home Healthcare Workers, Journal of the American Geriatrics Society . 2013, 61(10): 1824-1827.


Researcher : Chan VNY

Project Title:Hepatitis B virus array for genotyping and mutation detection
Investigator(s):Chan VNY, Lai CL, Chan K, Yuen RMF
Department:Medicine
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:11/2006




Researcher : Chan VSF

Project Title:Development of a humanized mouse systemic lupus erythematosus model for studying disease pathogenesis and evaluation of therapeutic treatment efficacy
Investigator(s):Chan VSF
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2011
Completion Date:09/2013


Project Title:Functional characterization of the novel C-type lectin-like receptor CLEC16A and its expression association in systemic lupus erythematosus
Investigator(s):Chan VSF, Lau WCS
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:Molecular profiling of pathogenic dendritic cells development in systemic lupus erythematosus
Investigator(s):Chan VSF
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012
Completion Date:09/2013


Project Title:Intracellular dynamics of CLEC16A
Investigator(s):Chan VSF, Yan S
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Chan V.S.F., Yan S., TAM C.Y., Shen N. and Lau W.C.S., MicroRNA modulations in plasmacytoid dendritic cells hyperactivity in systemic lupus erythematosus, The 15th International Congress of Immunology 2013, Milan, Italy. 2013.
Chan V.S.F., Plasmacytoid Dendritic Cells in SLE Pathogenesis, Autoimmunity Congress Asia. 2013.
Lin X., Rui K., Deng J., Tian J., Wang X., Wang S., Ko K.H., Jiao Z., Chan V.S.F., Lau W.C.S., Cao X. and Lu L., Th17 cells play a critical role in the development of experimental Sjogren's syndrome., Ann Rheum Dis. 2014.
YAN S., YIM L.Y., Lu L., Lau W.C.S. and Chan V.S.F., MicroRNA Regulation in Systemic Lupus Erythematosus Pathogenesis., Immune Netw. 2014, 14(3): 138-48.


Researcher : Chan WK

List of Research Outputs

Mok T.M.Y., WU H., Lau C.S. and Chan W.K., Phenotype and function of alternatively activated dendritic cells derived from patients with systemic lupus erythematosus, Annual Scientific meeting of Japan College of Rheumatology 2014, Japan. 2014.


Researcher : Chan YC

List of Research Outputs

Chan Y.C., TING S., Lee Y.K., Ng K.M., Zhang J., chen Z., Siu D.C.W., oh S.K.W. and Tse H.F., Electrical Stimulation Promotes Maturation of Cardiomyocytes Derived from Human Embryonic Stem Cells, Journal of Cardiovascular Translational Research. 2013, 6: 989-999.
ZHANG J., Ho J.C.Y., Chan Y.C., Lian Q., Siu D.C.W. and Tse H.F., Overexpression of myocardin induces partial transdifferentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells into cardiomyocytes, Physiological Reports. 2014, 2: n/a-n/a.


Researcher : Chan YCC

Project Title:DPP-4 inhibition protects diabetes-induced impairment in EPC function and vascular repair
Investigator(s):Chan YCC, Xu A
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:11/2014




Researcher : Chan YY

List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Leung J.C.K., Lim A.I., Chan Y.Y., Yiu W.H., Lai K.N. and Tang S.C.W., Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) Represses Albumin-Induced Chemokines and Adhesion Molecules Synthesis by Kidney Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 135A.
Lim A.I., Chan Y.Y., Tang S.C.W., Lai K.N. and Leung J.C.K., Albumin and Advanced Glycation Endproducts Activated KIM-1 Release by Proximal Tubular Epithelial Cells through Distinct Kinetics and Mechanism, J Am Soc Nephrol . 2013, 24: 326A.
Lim A.I., Chan Y.Y., Tang S.C.W., Yiu W.H., LI R., Lai K.N. and Leung J.C.K., BMP-7 represses albumin-induced chemokine synthesis in kidney tubular epithelial cells through destabilization of NF-κB-inducing kinase., Immunol Cell Biol.. 2014, 92(5): 427-35.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
Yiu W.H., WONG W.L.D., Leung J.C.K., Chan Y.Y., Lan H.Y., Lai K.N. and Tang S.C.W., Tissue Kallikrein Mediates Pro-Inflammatory Pathways in Proximal Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 315A.
Yiu W.H., WONG W.L.D., Chan Y.Y., Leung J.C.K., Chan K.W., lan H.Y., Lai K.N. and Tang S.C.W., Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells., PLoS One. 2014, 9 (2): e88894.


Researcher : Chang SKR

List of Research Outputs

Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lee C.Y., Lam C.L.D., Chang S.K.R., Pang Y.Y., Chang C., Lau G.K.K., Teo K.C., Ho S.L., Cheung R.T.F. and Chan K.H., Prognosis and Crisis in Generalised Myasthenia Gravis among Hong Kong Chinese, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drug resumption after antiplatelet-related intracerebral haemorrhage, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 40.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Siu D.C.W., Leung G.K.K., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drugs resumption after antiplatelet-related intracerebral haemorrhage in Chinese , 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.


Researcher : Chau KM

List of Research Outputs

Tan K.C.B., TSUN G.S., Yung S.S.Y., Chau K.M., Shiu S.W.M. and Chan D.T.M., Cholesterol transport proteins and diabetic nephropathy., World Diabetes Congress in Melbourne, Australia.. 2013.


Researcher : Chen C

Project Title:Potential roles of fibroblast growth factor 21 (FGF21) in the regulation of thermogenesis by thyroid hormone in brown adipose tissue
Investigator(s):Chen C, Lam KSL, Xu A
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:03/2012
Completion Date:09/2013




Researcher : Chen WH

Project Title:Enoxaparin combined with epitfibatide or abciximab versus unfractionated heparin combined with epitfibatide or abciximab in percutaneous coronary intervention: obersvations on efficacy, safety, anticoagulation profile, and level of platelet inhibition
Investigator(s):Chen WH, Lau CP
Department:Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:06/2001


Project Title:A prospective study to investigate the determinants of the quantity of embolized debris during native vessel percutaneous coronary intervention
Investigator(s):Chen WH, Lau CP
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:A prospective study to evaluate the relation between aspirin resistance and the incidence and magnitude of myonecrosis after percutaneous coronary intervention
Investigator(s):Chen WH, Lau CP
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2003




Researcher : Chen Y

List of Research Outputs

Yiu K.H., Lau G.K.K., Zhao C., Chan Y.H., Chen Y., Zhen Z., Wong A., Lau C.P. and Tse H.F., Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus, Cardiovascular Diabetology. 2014, 13:63: 1-8.
Yiu K.H., Wong A., Pu L., Chiang R., Sit K.Y., Chan D., Lee H.Y., Lam Y.M., Chen Y., Siu D.C.W., Lau C.P., Au K.W. and Tse H.F., Prognostic value of preoperative right ventricular geometry and tricuspid valve tethering area in patients undergoing tricuspid annuloplasty, Circulation. 2014, 129: 87-92.


Researcher : Cheng CTK

List of Research Outputs

Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.


Researcher : Cheng CW

Project Title:Potential oncogenic role of PIN1 in B-cell lymphoma
Investigator(s):Cheng CW, Tse EWC
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:12/2012
Completion Date:05/2014


List of Research Outputs

Cheng C.W., Kwong Y.L. and Tse E.W.C., Best Abstract in Basic Science & Translational (Poster), 19th Medical Research Conference Department of Medicine, HKU. 2014.


Researcher : Cheng KY

Project Title:The role of APPL2 in the regulation of insulin secretion and glucose homeostasis in mice
Investigator(s):Cheng KY, Xu A
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2013


Project Title:The role of hypothalamic APPL2 in energy metabolism
Investigator(s):Cheng KY, Xu A
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Cheng K.Y., Lam K.S.L., WANG B. and Xu A., Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin, Best Pract Res Clin Endocrinol Metab. 2014, 28: 3-13.
Cheng K.Y., Lam K.S.L., WANG B. and Xu A., Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin, Best Practice & Research Clinical Endocrinology & Metabolism. 2013.
Cheng K.Y., Zhu W., CHEN B., Wang Y., Wu D., Sweeney G., WANG B., Lam K.S.L. and Xu A., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle, Diabetes. 2014, DB_140337: Epub ahead of print.
Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte Fatty Acid Binding Protein Potentiates Toxic Lipids-induced Endoplasmic Reticulum Stress Via Inhibition Of JAK2-Dependent Autophagy , 12th International Congress on Obesity (ICO) . 2014.
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein potentiates palmitic acid induced endoplasmic reticulum stress in macrophages via inhibition of Janus kinase 2-dependent autophagy, Singapore Diabetes Forum 2014 . 2014.
Hoo R.L.C., LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and translational (Oral Presentation), 19th Medical Research Conference. 2014.
LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and Translational (Oral Presentation), 19th Medical Research Conference. 2014.
Li H., Wei S., Cheng K.Y., Gounko N.V., Ericksen R.E., Xu A., Hong W. and Han W., BIG3 inhibits insulin granule biogenesis and insulin secretion., EMBO Rep. 2014, [Epub ahead].
Park M., Wu D., Park T., Choi C., Li R., Cheng K.Y., Xu A. and Sweeney G., Appl1 transgenic mice are protected from high fat diet induced cardiac dysfunction, Am J Physiol Endocrinol Metab. 2013, Epub [2013 Aug 6].
Qiu B., Shi X., Wong E.T., Lim J., Bezzi M., Low D., Zhou Q., Akıncılar S.C., Lakshmanan M., Swa H.L., Tham J.M., Gunaratne J., Cheng K.Y., Hong W., Lam K.S.L., Ikawa M., Guccione E., Xu A., Han W. and Tergaonkar V., NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling., Cell Rep.. 2014, 7: 1876-1886.


Researcher : Cheng OY

List of Research Outputs

Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.


Researcher : Cheng YY

Project Title:The role of hypoxia inducible factor 1 alpha in NK/T-cell lymphoma
Investigator(s):Cheng YY, Tse EWC
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:12/2008




Researcher : Cheong MYY

List of Research Outputs

Lai Y.K.A., Lam C.M.J., Cheong M.Y.Y. and Ip M.S.M., The dose-response relationship between CPAP adherence and the daily performance in subjects with OSA, 18th Congress of the Asian Pacific Society of Respirologym Yokohama, Japan, Nov 2013. Respirology. 2013, 18(4): PS379.


Researcher : Cheung AHK

List of Research Outputs

Mak J.C.W., Ho S.P., Ho A.S., Law B.K., Cheung A.H.K., Ho J.C.M., Ip M.S.M. and Chan M.M.W., Sustained elevation of systemic oxidative stress and inflammation in exacerbation and remission of asthma, ISRN Allergy. 2013, 561831.


Researcher : Cheung BMY

Project Title:Does adrenomedullin reduce the inflammatory response caused by advanced glycation endproducts?
Investigator(s):Cheung BMY, Tan KCB, Lau WCS
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012
Completion Date:11/2013


Project Title:Does an elevated lipocalin-2 concentration in plasma lead to endothelial dysfunction and hypertension?
Investigator(s):Cheung BMY, Lam KSL, Tse HF, Wang Y
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2012


Project Title:Cost-effectiveness of testing for the HLA-B*5801 allele to prevent serious hypersensitivity reaction to allopurinol
Investigator(s):Cheung BMY, Cheung TT, Chau J, Lam MPS
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2013
Completion Date:03/2014


Project Title:Accelerating the Development of Pharmacogenomics at HKU through a Systems Biology Approach
Investigator(s):Cheung BMY
Department:Medicine
Source(s) of Funding:Innovative Research Grants
Start Date:07/2013


Project Title:Beta-2 Microglobulin as a Biomarker in Acute Coronary Syndrome
Investigator(s):Cheung BMY, Cheung CL
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Chen J., Zhou X., Li C. and Cheung B.M.Y., Risk of stroke due to spontaneous cervical artery dissection., Intern Med.. 2013, 52(19): 2237-40.
Cheung B.M.Y., 17th World Congress of Basic & Clinical Pharmacology 13-18 July 2014 at the CTICC in Cape Town, South Africa. 2014.
Cheung B.M.Y., 5th Asian Preventive Cardiology & Cardiac Rehabilitatin Conference, Hong Kong, The treatment treshold and target for hypertension should be more lenient in Elderly: the Cons.. 2014.
Cheung B.M.Y., 8th Asian Conference on Pharmacoepidemiology, Hong Kong, Pharmacoepidemiology in Hong Kong - the case for more research. 2013.
Cheung B.M.Y., Annual scientific Meeting of teh Federation of Medical societies of Hong Kong 2013, Obesity - a common cause of hypertension. 2013.
Cheung B.M.Y., Associate Editor , The Open Hypertension Journal. 2013.
Cheung B.M.Y., Editor, American Journal of Hypertension. 2013.
Cheung B.M.Y., Editor, Scientific Reports, Editorial Board. 2014.
Cheung B.M.Y., Editorial Board Member, Advances in Public Health. 2014.
Cheung B.M.Y., European Association for Clinical Pharmacology & Therapeutics , International Editorial Board Member. 2014.
Cheung B.M.Y. and Deng H., Fibroblast growth factor 21: a promising therapeutic target in obesity-related diseases., Expert Rev Cardiovasc Ther.. 2014, 12(6): 659-66.
Cheung B.M.Y., Hong Kong Cardiovascular Task Force workshop, Hong Kong, Hong Kong Cardiovascular Task Force Risk Management Programe Results Summary & Discussion. 2014.
Cheung B.M.Y., Hong Kong Medical Journal Best Original Paper Award 2013, Hong Kong Medical Association. 2013.
Cheung B.M.Y., Interview on the EXAMINE Study and the write-up titled "Study confirms alogliptin safety in diabetics with high CV risk" in Medical Tribune, MIMS Hong Kong Limited. 2013, 33.
Cheung B.M.Y., Physicians' Academy for Cardiovascular Education, Hanoi, Hypertension management in Asia: what are the current issues and unmet needs?. 2013.
Cheung B.M.Y., Resistant Hypertension, International Conference on Cardiology, CUHK-Mayo Clinic-Asia Cardiovascular Summit & 2nd Antithrombotic Pharmaceutical Symposium. 2013.
Cheung B.M.Y., Tenth Symposium on Healthy Aging, Hong Kong, New Hypertension Guidelines and teh Implications for Pharmacological Treatment. 2014.
Cheung B.M.Y., The metabolic syndrome in Asia: what are the opportunities for intervention?, The 9th Scientific Conference on Cardiovascular Sciences Across the Strait and The 1st Southern Taiwan International Scientific Conference on Cardiac-Cerebral Vascular Sciences, Taiwan, Aug 2013. 2013.
Cheung B.M.Y., What physicians need to know about biosimilars, 4th Oncology Forum, Hong Kong. 2013.
Cheung B.M.Y., What physicians need to know about biosimilars, Hong Kong J Radiol. 2013, 16(4) Suppl: S50-4.
Cheung C.L., Cheung T.T., Lam K.S.L. and Cheung B.M.Y., High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. adults., Clin Nutr. 2013, 32(6): 1055-60.
Cheung C.L., Sahni S., Cheung B.M.Y., Sing C.W. and Wong I.C., Vitamin K intake and mortality in people with chronic kidney disease from NHANES III. [Epub ahead of print], Clin Nutr.. 2014, pii:S0261-5614(14): 00086-7.
Cheung C.L., Sahni S., Cheung B.M.Y., Sing C.W. and Wong I.C.K., Vitamin K intake reduces mortality in people with chronic kidney disease, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung C.L., Tan K.C.B., Lam K.S.L. and Cheung B.M.Y., modelling approach, 19th Medical Research Conference.Hong Kong Medical Journal. 2014, 14.
Cheung T.T. and Cheung B.M.Y., Managing blood pressure control in Asian patients: safety and efficacy of losartan., Clin Interv Aging.. 2014, 9: 443-50.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Chow W.S., Yuen M.M.A., Lee P.C.H., Woo Y.C., Tso A.W.K., Xu A., Fong H.Y., Cheung B.M.Y. and Lam K.S.L., Circulation fibroblast growth factor 21 levels predict incident hyperglycaemia in Chinese subject without the metabolic syndrome, IDF World Diabetes Congress, 2-6 Dec 2013, Melbourne, Australia. 2013.
Chow W.S., Xu A., Woo Y.C., Tso A.W.K., Cheung C.W.S., Fong H.Y., Tse H.F., Chau M.T., Cheung B.M.Y. and Lam K.S.L., Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arterioscler Thromb Vasc Biol . 2013, 33: 2454-9.
Kumana C.R., Cheung B.M.Y. and Tse H.F., Relative versus absolute drug-therapy benefits and safety: Lessons from ARISTOTLE, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 25.
Ong K.L., Allison M.A., Cheung B.M.Y., Wu B.J., Barter P.J. and Rye K.A., The relationship between total bilirubin levels and total mortality in older adults: the United States National Health and Nutrition Examination Survey (NHANES) 1999-2004., PLoS One. . 2014, 9(4): e94479.
Peng H., Cai X.Q., Tsang T.K., Shen H.S., Wu X.H., Zhou Y.B., LI C. and Cheung B.M.Y., Do unsaturated fatty acids have beneficial effect on reduction of stroke risk in hypertensive population?, 17th Annual Scientific Meeting Institute of Cardiovasclar Science and Medicine 23 November 2013, Hong Kong. 2013, 21: 72.
SAMARANAYAKE N.R., Cheung S.T., Cheung K., Lai K., Chui W.C. and Cheung B.M.Y., Implementing a bar-code assisted medication administration system: effects on the dispensing process and user perceptions., Int J Med Inform.. 2014, 83(6): 450-8.
SAMARANAYAKE N.R., Dabare P.R.L., Wanigatunge C.S. and Cheung B.M.Y., SLMA 126th Anniversary Sceintific Medical Congress 2013.
SAMARANAYAKE N.R., Dabare P.R., Wanigatunge C.A. and Cheung B.M.Y., The pattern of abbreviation use in prescriptions: a way forward in eliminating error-prone abbreviations and standardisation of prescriptions., Curr Drug Saf. 2014, 9(1): 34-42.
SONG E., Fan P., Huang B., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice, J Am Heart Assoc.. 2014, 3: e000837.
Samartzis D., Bow H.Y.C., Karppinen J.I., Luk K.D.K., Cheung B.M.Y. and Cheung K.M.C., Family history of low back pain is a significant predictor of pain and disability between extreme stages of lumbar disc degeneration, World Forum for Spine Research - Intervertebral Disc—from Degeneration to Therapeutic Motion Preservation. Xi'An, China, 2014.
Samartzis D., Bow H.Y.C., Karppinen J.I., Luk K.D.K., Cheung B.M.Y. and Cheung K.M.C., Hypertension is independently associated with lumbar disc degeneration: a large-scale population-based study, World Forum for Spine Research - Intervertebral Disc—from Degeneration to Therapeutic Motion Preservation. Xi'An, China, 2014.
Shiu S.W.M., Xiao S., Wang Y., Chow W.S., Lam K.S.L. and Cheung B.M.Y., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clin Sci (Lond). 2014, 126: 175-81.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.
Thomas G.N., Macfarlane D.J., Guo B., Cheung B.M.Y., McGhee S., Chou K.L., Deeks J.J., Lam T.H. and Tomlinson B., Pedometry and 'peer support' in older Chinese adults: A 12-month cluster randomised controlled trial, Hong Kong Medical Journal. 2014, 20(Suppl 3): S11-4.
WONG H.K., Ong K.L., Leung Y.H., Lam T.H., Thomas G.N., Lam K.S.L. and Cheung B.M.Y., A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels, Clinical Endocrinology. 2013, 79(4): 504-9.
WONG H.K., Tang F., Cheung T.T. and Cheung B.M.Y., Adrenomedullin and diabetes., World J Diabetes.. 2014, 5(3): 364-71.
WONG H.K., Leung Y.H. and Cheung B.M.Y., Effects of advanced glycation endprouducts on adrenomedullin gene expression in macrophages, 17th Annual Scientific Meeting Institute of Cardiovasclar Science and Medicine 23 November 2013, Hong Kong. 2013, 21: 69.
WONG H.K., ONG K.L., Cheung C.L. and Cheung B.M.Y., Utilization of glucose, blood pressure, and lipid lowering medications among people with type II diabetes in the United States, 1999-2010., Ann Epidemiol. . 2014, 24(7): 516-21.
Yeung C.Y., Hui Y.L.E., Lam T.H., Chow W.S., Woo Y.C., Fong H.Y., Xu A., Cheung B.M.Y. and Lam K.S.L., Plasma fibrinogen level as a predictor of incident metabolic syndrome in a community-based prospective study in Hong Kong Chinese, European Association for the Study of Diabetes. 2013.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.


Researcher : Cheung CL

Project Title:Identification of susceptibility locus of Stevens-Johnson Syndrome and Toxic Epidermal Necrosis in Hong Kong Chinese
Investigator(s):Cheung CL, Cheung BMY, Wong ICK, Sham PC, Chan CYJ
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:Epidemiological study of serious adverse drug reactions in Hong Kong
Investigator(s):Cheung CL
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Cheung C.L., Best Abstract Award in Poster presentation, 19th Medical Research Conference, the University of Hong Kong. 2014.
Cheung C.L., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Genetic variant in vitamin D binding protein is associated with serum 25-hydroxyvitamin D and vitamin D insufficiency in southern Chinese., J Hum Genet. 51, 2013, 58: 749.
Cheung C.L., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Genetic variants in GREM2 are associated with bone mineral density in a southern Chinese population, Journal of Clinical Endocrinolog and Metabolism. 2013, 98: E1557-61.
Cheung C.L., Cheung T.T., Lam K.S.L. and Cheung B.M.Y., High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. adults., Clin Nutr. 2013, 32(6): 1055-60.
Cheung C.L., Lau K.S., Sham P.C. and Kung A.W.C., Research Output Prize, Faculty of Medicine, the University of Hong Kong. 2013.
Cheung C.L., Sahni S., Cheung B.M.Y., Sing C.W. and Wong I.C., Vitamin K intake and mortality in people with chronic kidney disease from NHANES III. [Epub ahead of print], Clin Nutr.. 2014, pii:S0261-5614(14): 00086-7.
Cheung C.L., Sahni S., Cheung B.M.Y., Sing C.W. and Wong I.C.K., Vitamin K intake reduces mortality in people with chronic kidney disease, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung C.L., Tan K.C.B., Lam K.S.L. and Cheung B.M.Y., modelling approach, 19th Medical Research Conference.Hong Kong Medical Journal. 2014, 14.
WONG H.K., ONG K.L., Cheung C.L. and Cheung B.M.Y., Utilization of glucose, blood pressure, and lipid lowering medications among people with type II diabetes in the United States, 1999-2010., Ann Epidemiol. . 2014, 24(7): 516-21.


Researcher : Cheung KF

Project Title:Serum levels and intra-renal expression of annexin II in patients and mice with lupus nephritis, and their correlation with disease activity
Investigator(s):Cheung KF, Chan DTM, Yung SSY
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2014




Researcher : Cheung RTF

Project Title:Role of ischemia in Alzheimer's disease - an experimental study in transgenic mice
Investigator(s):Cheung RTF
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Development of Chinese-language versions of internationally-accepted stroke training materials for healthcare professionals treating Chinese stroke patients
Investigator(s):Cheung RTF
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2005


Project Title:Neuroprotective effects of melatonin and/or electro-acupuncture (EA) on focal cerebral ischemia in rats
Investigator(s):Cheung RTF
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2009


Project Title:A pilot study of silent brain infarcts in healthy hypertensive elderly Chinese: the first 100 subjects
Investigator(s):Cheung RTF
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2012
Completion Date:04/2015


Project Title:Adverse effects of up-regulated adiponectin level on immune system in mice stroke models. Part I: effects of exogenous PPARgamma antagonist (BADGE) in wide type and transgenic mice.
Investigator(s):Cheung RTF
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:03/2013


Project Title:Neuroprotection of melatonin and calpeptin in a rat ischemic stroke model
Investigator(s):Cheung RTF
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2014


List of Research Outputs

Cheung R.T.F., Associate Editor, Advances in Alzheimer's Disease. Scientific Research Publishing, 2014.
Cheung R.T.F., Chairman of Free Paper Session 5, Chairman of Oral Session 13, Member of Scientific Committee & Faculty, Asia Pacific Stroke Conference 2013 (APSC 2013), Hong Kong Convention and Exhibition Centre, Wanchai, Hong Kong. 2013.
Cheung R.T.F., Editorial Board, Asian Journal of Neuroscience. Hindawi Publishing, 2014.
Cheung R.T.F., Editorial Board, Austin Journal of Cerebrovascular Disease & Stroke. Austin Publishing Group, 2014.
Cheung R.T.F., Editorial Board, Chinese Journal of Neurology. Chinese Medical Association, 2014.
Cheung R.T.F., Editorial Board, Chinese version of Stroke. 2014.
Cheung R.T.F., Editorial Board, Edorium Journal of Neurology. Edorium Journal, 2014.
Cheung R.T.F., Editorial Board, JSM Ophthalmology. JSciMedCentral, 2014.
Cheung R.T.F., Editorial Board, Journal of Pineal Research. Blackwell Publishing, 2014.
Cheung R.T.F., Editorial Board, Medical Progress. CMPMedica, 2013.
Cheung R.T.F., Editorial Board, Reviews on Recent Clinical Trials. Bentham Science Publishers, 2014.
Cheung R.T.F., Editorial Board, Stroke Research and Treatment. Hindawi Publishing Corporation, 2014.
Cheung R.T.F., Editorial Board, The Open Medical Imaging Journal. Bentham Science Publishers, 2014.
Cheung R.T.F., Editorial Board, The Open Neuroimaging Journal. Bentham Science Publishers, 2014.
Cheung R.T.F., Editorial Board, The Open Nuclear Medicine Journal. Bentham Science Publishers, 2014.
Cheung R.T.F., Editorial Board, The Open Physiology Journal. Bentham Science Publishers, 2014.
Cheung R.T.F., Editorial Board, World Journal of Biological Chemistry. Baishideng Publishing Group, 2014.
Cheung R.T.F., Experimental study in rat ICH model on pathophysiology and treatment, Symposium on Experimental Brain Haemorrhages, 5th World Conference of Intracerebral Haemorrhgae (ICH) and our 20th Annual Scientific meeting (ASM) of the Hong Kong Neurosurgical Society, Hong Kong Convention and Exhibition Centre, Hong Kong. 2013.
Cheung R.T.F., Member of Scientific Committee and Faculty, 5th World Conference of Intracerebral Haemorrhgae (ICH) and 20th Annual Scientific meeting (ASM) of the Hong Kong Neurosurgical Society, Hong Kong Convention and Exhibition Centre, Wanchai, Hong Kong . 2013.
Cheung R.T.F., Member of Scientific Programme Committee Session Chairperson in Breakout Session 6 - Headache and Pain (ARCH-IHS Joint Symposium), 14th Asian Oceanian Congress of Neurology (AOCN 2014), 2-5 March 2014, The Venetian Macao, Macao . 2014.
Cheung R.T.F., Pathophysiology and Treatment of Intracerebral Hemorrhage, Oral Session 13: Translational Research, Asia Pacific Stroke Conference 2013, Hong Kong Convention and Exhibition Centre, Hong Kong. 2013.
Cheung R.T.F., Regional Editor, Cardiovascular & Hematological Agents in Medicinal Chemistry. Bentham Science Publishers, 2013.
Cheung R.T.F., Stroke-related visual problems, Third Primary Eye Care Conference, Hong Kong Polytechnic University, Hong Kong. 2013.
FENG Y. and Cheung R.T.F., Neuroprotective effects of melatonin and calpeptin in a rat model of focal cerebral ischemia, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 18.
Gao J., Cheung R.T.F., Fan J., Hung Y.S., Sik H.H., So A. and Zhang Z., The complexity of brain dynamics increased with age: an EEG Study. , Human Brain Mapping. 2014, Hamburg.. 2014.
Gao J., Cheung R.T.F., Chan Y.S., Chu L.W., Mak H.K.F. and Lee T.M.C., The relevance of short-range fibers to cognitive efficiency and brain activation in aging and dementia., PLoS ONE. 2014, 9(4): e90307.
Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon S.F.K., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality, PLoS One. 2014, 9(2): e88283.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S., Hon S.F., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality., Plos One . 2014, 11:9(2): e882883.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon F.K.S., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with cancer are at increased risk of recurrent stroke and cardiovascular mortality, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chan Y.H., Teo K.C., Chan K.H., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases – Relationships and comparisons with vascular markers of atherosclerosis, Atherosclerosis. 2014, 235(1): 230-235.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lau G.K.K., Wong Y.K., Chang R.S.K., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, European Journal of Neurology. 2014, 21(2): 319-325.
Lee C.Y., Lam C.L.D., Chang S.K.R., Pang Y.Y., Chang C., Lau G.K.K., Teo K.C., Ho S.L., Cheung R.T.F. and Chan K.H., Prognosis and Crisis in Generalised Myasthenia Gravis among Hong Kong Chinese, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.
SANG Y., Yang X., Ellis-Behnke R.G., So K.F. and Cheung R.T.F., A self-assembling peptide nanofiber scaffold reduces acute brain injury and improves functional recovery in a hypertensive rat model of intracerebral hemorrhage plus clot aspiration, The Conjoint Congress of the 5th World ICH Conference 2013 & 20th Annual Scientific Meeting of Hong Kong Neurosurgical Society. 2013, 106.
SANG Y., Yang X., Su H., Leung G.K.K., Wu W. and Cheung R.T.F., Transplantation of NPCs into the hematoma cavity improves functional outcome in a rat model of intracerebral hemorrhage, The Conjoint Congress of the 5th World ICH Conference 2013 & 20th Annual Scientific Meeting of Hong Kong Neurosurgical Society. 2013, 69-70.
Sang L.Y.H., Liang Y., Li Y., Wong W.M., Tay D.K.C., So K.F., Ellis-Behnke R.G., Wu W. and Cheung R.T.F., A self-assembling nanomaterial reduces acute brain injury and enhances functional recovery in a rat model of intracerebral hemorrhage, Nanomedicine: Nanotechnology, Biology and Medicine. 2014, Epub on 2014-06-04.
Sang Y., Liang Y., Behnke E.R.G., So K.F. and Cheung R.T.F., A self-assembling peptide nanofiber scaffold reduces acute brain injury and improves functional recovery in a hypertensive rat model of intracranial hemorrhage plus clot aspiration, The 5th World Conference of Intracerebral Hemorrhage & 20th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, China, 2-4 November 2013.
Sang Y., YANG X., Su H.X., Leung G.K.K., Wu W. and Cheung R.T.F., Local transplantation pf NPC in a rat model of intracerebral hemorrhage plus hematoma evacuation, Cell Symposia: Using Stem Cells to Model and Treat Human Disease, Los Angeles, U.S.A., 21-23 November 2013.
Sang Y., YANG X., Su H.X., Leung G.K.K., Wu W. and Cheung R.T.F., Transplantation of neural progenitor cells into the hematoma cavity improves functional outcome in a rat model of intracerebral hemorrhage, The 5th World Conference of Intracerebral Hemorrhage & 20th Annual Scientific Meeting of the Hong Kong Neurosurgical Society, Hong Kong, China, 2-4 November 2013.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drug resumption after antiplatelet-related intracerebral haemorrhage, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 40.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Siu D.C.W., Leung G.K.K., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drugs resumption after antiplatelet-related intracerebral haemorrhage in Chinese , 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelt drug resumption after antiplatelet-related intracerebral haemorrhage, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Best Free Paper Award (First Runner-up): Antiplatelet Drugs Resumption after Antiplatelet-related Intra-cerebral Haemorrhage, 14th Asian & Oceanian Congress of Neurology. 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intra-cerebral haemorrhage in Hong Kong, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intracerebral hemorrhage in Hong Kong Chinese, Neurological Research. 2014, 36: 143-149.
XIE B., Au Yeung K.M., Tse H.F. and Cheung R.T.F., Aspirin resistance and silent brain infarcts in asymptomatic aspirin users, Asia Pacific Stroke Conference 2013. 36 (supp 1): 94.
XIE B., ZHANG M., Mak H.K.F. and Cheung R.T.F., Blood pressure variability, silent cerebrovascular lesions and cognitive impairment in healthy hypertensive elderly Chinese, 18th Research Postgraduate Symposium. 2013, 3.18.
XIE B., ZHANG M., Mak H.K.F. and Cheung R.T.F., Visit-to-visit blood pressure variability is associated with periventricular white matter hyperintensity in healthy hypertensive elderly Chinese, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 46.
ZHANG M., XIE B., Mak H.K.F. and Cheung R.T.F., Absence of association between arterial stiffness and white matter hyperintensities in otherwise healthy hypertensive elderly Chinese, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 51.
ZHANG M., XIE B., Mak H.K.F. and Cheung R.T.F., Arterial stiffness and white matter hyperintensities in healthy hypertensive elderly Chinese, 18th Research Postgraduate Symposium. 2013, 5.26.
Zhang L., Cheung R.T.F., Chu L.W. and Mak H.K.F., Zhang L, Cheung RTF, Chu LW, Mak HKF. Structural MRI measures in Alzheimer's disease and effects of ethnicity. , Alzheimer’s Association International Conference, 2013. . 2013.
Zhao Y., So R.H.Y., Chan C., Cheung R.T.F. and Arnold W., Cortical responses of human to linear and circular whole-body motion - a Near-Infrared Spectroscopy study, 4th International Symposium of Visual IMage Safety. 2013.


Researcher : Cheung TT

Project Title:Cost of illness of Ankylosing Spondylitis in Hong Kong
Investigator(s):Cheung TT, Lau WCS, Cheung BMY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Cheung C.L., Cheung T.T., Lam K.S.L. and Cheung B.M.Y., High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. adults., Clin Nutr. 2013, 32(6): 1055-60.
Cheung T.T. and Cheung B.M.Y., Managing blood pressure control in Asian patients: safety and efficacy of losartan., Clin Interv Aging.. 2014, 9: 443-50.
Lau W.C.S., Au Y.L., Chan Y.Y., Chan Y.T., Chan O.W., Cheung T.T., Chung H.Y., Ho C.T.K., Kowk S.K., Lee W.S., Li W.L., Lui M.S., Mok T.M.Y., Tang L.M., Tsang H.L., Yuen K.Y.C. and Wong R.W.S., Outstanding Team 2014, Hong Kong West Cluster cum Queen Mary Hospital. 2014.
Mok C.C., Tam L.S., Leung M.H., Ying K.Y., To C.H., Lee K.L., Ho L.Y., Yip M.L., Tsui H.S., Chan T.H., Lee K.W., Li E.K., Hong Kong Society of Rheumatology , Chan E.Y., Chan K.H., Chan K.M., Chan K.Y., Chan P.S., Chan Y.K., Chau S.Y., Cheung T.C., Cheung T.T., Chung H.Y., Ho C.T.K., Kun E., Kwok L.W., Kwok M.L., Kwok K., Lam C.K., Lao W.N., Lau W.C.S., Lau Y.L., Lee A.K., Lee T.K., Lee K.K., Lee M.Y., Lee S.S., Lee T.L., Yan T., Leung M.C., Li W.L., Liu H.M., Luk M.C., Ma K.Y., Mak L.W., Mok T.M.Y., Ng K.H., Ng W.L., So H., Sung C.K., Tan R.F., Tang S.K., Wan M.C., Wong C.H., Wong K.C., Man S., Wong P.Y., Wong J., Wong R.W.S., Woo W.S., Young K.Y., Yim C.W., Yu K.L., Yuen K.Y.C. and Yung K.M., Referral strategy for early recognition of axial spondyloarthritis: consensus recommendations from the Hong Kong Society of Rheumatology., Int J Rheum Dis. 2013, 16(5): 500-8.
WONG H.K., Tang F., Cheung T.T. and Cheung B.M.Y., Adrenomedullin and diabetes., World J Diabetes.. 2014, 5(3): 364-71.


Researcher : Cheung YM

List of Research Outputs

Cheung Y.M., Leung A.Y.H., Chan S.C., Trendell-Smith N.J., So C.C. and Kwong Y.L., Fatal graft-versus-host disease after unrelated cadaveric liver transplantation due to donor/recipient human leucocyte antigen matching (Letter to the Editor), Internal Medicine Journal. 2014, 44(4): 425-426.


Researcher : Cheung YY

Project Title:Impact of newly identified type 2 diabetes susceptibility loci on the risk of coronary artery disease among patients with T2DM.
Investigator(s):Cheung YY, Lam KSL
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2013


List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.


Researcher : Chim JCS

Project Title:FISH study and the use of bortezomib in high-risk multiple myeloma
Investigator(s):Chim JCS
Department:Medicine
Source(s) of Funding:Lee Hysan Foundation - General Award
Start Date:07/2008


Project Title:Study of methylation of microRNA in mantle cell lymphoma
Investigator(s):Chim JCS
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Methylation of miR-224 in haematological cancers
Investigator(s):Chim JCS
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012
Completion Date:05/2014


Project Title:Genetic study (FISH study) for personalized treatment of multiple myeloma
Investigator(s):Chim JCS
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:11/2012


Project Title:Epigenetic silencing of tumour suppressor miR-212/132 cluster in Philadelphia-negative myeloproliferative neoplasm
Investigator(s):Chim JCS
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:Use of Bortezomib during conditioning of autologous stem cell transplantation of international stage III myeloma
Investigator(s):Chim JCS, Kwong YL, Lie AKW
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:03/2014


Project Title:Epigenetic silencing of MIR-340 in haematological malignancies
Investigator(s):Chim JCS
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Chan S.Y., Gill H., Hwang Y.Y.G., Sim J., Tse C.T.A., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Annals of Hematology. 2014, 93(3): 493-498.
Chan T.S., Gill H., Hwang Y.Y., Sim P.Y.J., Tse A.C., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Ann Hematol. 2013, Epub ahead of print.
Chim J.C.S., Advances in Myeloma Treatment, 3rd Annual Updates on Breakthroughs in Hematology (AUBH2013), organized by The APHCON (Asia-Pacific Hematology Consortium), Thailand. 2013.
Chim J.C.S., American Journal of Molecular Biology, 2013.
Chim J.C.S., American Journal of Translational Research, 2014.
Chim J.C.S. and Ma E.S.K., An extraordinary survival of >20 years in a myeloma patient with an unusual combination of t(14;16) and hyperdiploidy, Oncology letter. 2013, 6(6): 1663-1664.
Chim J.C.S., Blood Cancer Journal (http://www.nature.com/bcj/about/index.html#Editors) , 2014.
Chim J.C.S., Bone Marrow Transplantation (impact factor :3.6) , 2014.
Chim J.C.S., Cancer Reports (BioMed Best), 2014.
Chim J.C.S., Carcinogenesis (impact factor :5.4) , 2014.
Chim J.C.S., Case Reports in Oncological Medicine . 2013.
Chim J.C.S., Clinical Epigenetics, 2013.
Chim J.C.S., Editor-in-Chief, Journal of Genetics Study . 2013.
Chim J.C.S., Epigenetic Alterations in multiple myeloma and/or The Myeloma Study in Hong Kong, 1st Union Summit Forum on Lymphoid Malignancies, organized by Institute of hematology and Blood Diseases hospital, Chinese Academy of Medical Sciences (IHCAMS) and Hematological Oncology Committee of China Anti-Cancer Association, Tianjin/China. 2013.
Chim J.C.S., Epigenomics (impact factor:3.429), 2013.
Chim J.C.S., Frontiers in Biological Chemistry . 2013.
Chim J.C.S., Frontiers in Epigenomics, 2013.
Chim J.C.S., Global Journal of Hematology and Blood Transfusion. 2014.
Chim J.C.S., Health (http://www.scirp.org/journal/health), 2013.
Chim J.C.S., Hematology and Leukemia (Herbert Open Access Journals), 2014.
Chim J.C.S., International Journal of Advanced Chemistry Research (IJACR) . 2013.
Chim J.C.S., International Journal of Health, 2014.
Chim J.C.S., International Journal of Health . 2014.
Chim J.C.S., International Journal of Oncology (impact factor: 2.57) , 2014.
Chim J.C.S., Journal of Applied Scientific Reports . 2013.
Chim J.C.S., Journal of Applied Scientific Reports . 2013.
Chim J.C.S., Journal of Genetics Study, 2014.
Chim J.C.S., Journal of Hematology Oncology (IF: 3.99), 2014.
Chim J.C.S., Journal of Hematology, Blood Transfusion and Disorders (HBTD. 2014.
Chim J.C.S., Journal of Life Medicine, 2014.
Chim J.C.S., Journal of Transplantation Technology, 2014.
Chim J.C.S., Management of Myeloma in countries with limited access to novel agents, 4th Conference of Myanmar Society of Haematology, organized by Myanmar Society of Haematology of Myanmar Medical Association, Myanmar. 2013.
Chim J.C.S., Modern Chemotherapy . 2013.
Chim J.C.S., Molecular Biology and Genetic Engineering , 2014.
Chim J.C.S., PLoS ONE (impact factor: 4.41), 2013.
Chim J.C.S., Scientifica, 2014.
Chim J.C.S., Senior Editor, Journal of Gene Therapy . 2013.
Chim J.C.S., The Asia-Pacific Journal of Oncology and Hematology. 2014.
Chim J.C.S., The Hong Kong Medical Diary. 2014.
Chim J.C.S., The Open Leukemia Journal. 2013.
Chim J.C.S., The Open Pathology Journal. 2014.
Chim J.C.S., The Open Surgical Oncology Journal. 2014.
Chim J.C.S., The Open Translational Medicine Journal. 2013.
Chim J.C.S., Translational Oncology (impact factor: 2.40), 2014.
Chim J.C.S., Transplant-eligible Myeloma: What is the next clinical question?, 15th Beijing/Hong Kong Medical Exchange, organized by Hong Kong Medical Association, Hunan, China. 2013.
Chim J.C.S., Transplantation Technology . 2014.
Chim J.C.S., Trends in Molecular Biology . 2013.
Chim J.C.S., Liu H., Lie A.K.W., Chan Y.T.E., Ho S., Wong M. and Kwong Y.L., Unsustained CR of less than 24 months after autologous stem cell transplantation predicts aggressive myeloma with short survival, Hematol Oncol. 2014, Epub ahead of print.
Chim J.C.S., 《白血病•淋巴瘤》雜誌 , 2014.
Chng W.J., Dispenzieri A., Chim J.C.S., Fonseca R., Goldschmidt H., Lentzsch S., Munshi N., Palumbo A., San Miguel J., Sonneveld P., Usmani S., Durie B.G. and Avet-Loiseau H., IMWG consensus on risk stratification in multiple myeloma, Leukemia. 2013, Epub ahead of print.
HO C.H.I.-.L.A.I., Chen S., Leung Y.L., Cheng T., Wong K.A.-.N.I.N., Cheung S.K., Liang R. and Chim J.C.S., 11C-Acetate for Metabolic Characterization of Multiple Myeloma – A Comparative PET/CT Study with 18F-Fluorodeoxyglucose PET/CT , Journal of Nuclear Medicine. 2014, 55(5): 749-752.
Kim K., Lee J.H., Kim J.S., Min C.K., Yoon S.S., Shimizu K., Chou T., Kosugi H., Suzuki K., Chen W., Hou J., Lu J., Huang X.J., Huang S.Y., Chng W.J., Tan D., Teoh G., Chim J.C.S., Nawarawong W., Siritanaratkul N. and Durie B.G., Clinical profiles of multiple myeloma in Asia-An Asian Myeloma Network study, Am J Hematol. 2014, 89(7): 751-756.
Kwong Y.L., Singh G.H.H., Leung A.Y.H., Tse E.W.C., Lie A.K.W., Hwang Y.Y.G., Chan T.S.Y. and Chim J.C.S., Faculty Knowledge Exchange (KE) Award 2013: 'Multi-media Haematology Protocol: Haematology Protocol Book, iPad/iPhone App, Internet Website' (Group Award) , The University of Hong Kong. 2013.
Kwong Y.L., Pang A.W.K., Leung A.Y.H., Chim J.C.S. and Tse E.W.C., Quantification of circulating Epstein-Barr virus DNA in NK/T-cell lymphoma treated with the SMILE protocol: diagnostic and prognostic significance, Leukemia. Epub ahead of print, 2013, Epub.
NG H.Y., Wan T.S.K., So J.C.C. and Chim J.C.S., Epigenetic inactivation of DAPK1, p14ARF, mir-34a and -34b/c in acute promyelocytic leukemia, Journal of Clinical Pathology. 2014, 67(6): 626-631.
Ocio E.M., Richardson P.G., Rajkumar S.V., Palumbo A., Mateos M.V., Orlowski R., Kumar S., Usmani S., Roodman D., Niesvizky R., Einsele H., Anderson K.C., Dimopoulos M.A., Avet-Loiseau H., Mellqvist U.H., Turesson I., Merlini G., Schots R., McCarthy P., Bergsagel L., Chim J.C.S., Lahuerta J.J., Shah J., Reiman A., Mikhael J., Zweegman S., Lonial S., Comenzo R., Chng W.J., Moreau P., Sonneveld P., Ludwig H., Durie B.G. and San Miguel J.F., New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the international myeloma working group (IMWG), Leukemia. 2013, 28(3): 525-542.
Tan D., Chng W.J., Chou T., Nawarawong W., Hwang S.Y., Chim J.C.S., Chen W., Durie B.G. and Lee J.H., Management of multiple myeloma in Asia: resource-stratified guidelines, Lancet Oncol. 2013, 14(12): e571-81.
WANG L., Kwong Y.L., Wong K.F., Kho C.S.B., Jin D., Tse E.W.C., Rosen A. and Chim J.C.S., Epigenetic inactivation of miR-34b/c in addition to miR-34a and DAPK1 in chronic lymphocytic leukemia, J Transl Med. 2014, 12(1): 52.
Wang L.Q., Kwong Y.L., Wong K.F., Kho C.S.B., Jin D., Tse E.W.C., Rosen A. and Chim J.C.S., Epigenetic inactivation of miR-34b/c in addition to miR-34a and DAPK1 in chronic lymphocytic leukemia, Journal of Translational Medicine. 2014, 12: 52-61.
Wang L.Q., Kwong Y.L., Kho C.S., Wong K.F., Wong K.Y., Ferracin M., Calin G.A. and Chim J.C.S., Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic leukemia - implications on constitutive activation of NFkappaB pathway, Mol Cancer.. 2013, 12: 173.
Wong K.Y., Wan T.S.K., So J.C.C. and Chim J.C.S., Establishment of a Chinese human multiple myeloma cell line: MMLAL, Cancer Cell Int. . 2013, 13(1): 122.
Yuan L., Chan G.C.F., Fung K.L. and Chim J.C.S., RANKL Expression in Myeloma Cells is regulated by a network involving RANKL promoter methylation, DNMT1, microRNA and TNFα in the Microenvironment, Biochim Biophys Acta - Molecular Cell Research. 2014, 1843(9): 1834-1838.
Zhang M.Y., Fung T.K., Chen F.Y. and Chim J.C.S., Methylation Profiling of SOCS1, SOCS2, SOCS3, CISH and SHP1 in Philadelphia-negative (Ph-ve) Myeloproliferative Neoplasm (MPN), Journal of Cellular and Molecular Medicine. 2013, 17(10): 1282-90.


Researcher : Chow CH

List of Research Outputs

HE B., SHI X., Man C.H., Ma C.H., Ekker S.C., Chow C.H., So C.W., Choi W.L., Zhang W., Zhang Y. and Leung A.Y.H., Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia., Blood. USA, American Society of Hematology, 2014, 123: 2518-2529.
Lai W.Y., Li Y.Y., Mak T., HO F.C., Chow S.T., CHOOI W.H., Chow C.H., Leung A.Y.H. and Chan B.P., Reconstitution of bone-like matrix in osteogenically differentiated mesenchymal stem cells (MSC)-collagen constructs - A 3D in vitro model to study haematopoietic stem cell (HSC) niche., Journal of Tissue Engineering. 2013.


Researcher : Chow WS

List of Research Outputs

Chow W.S., Yuen M.M.A., Lee P.C.H., Woo Y.C., Tso A.W.K., Xu A., Fong H.Y., Cheung B.M.Y. and Lam K.S.L., Circulation fibroblast growth factor 21 levels predict incident hyperglycaemia in Chinese subject without the metabolic syndrome, IDF World Diabetes Congress, 2-6 Dec 2013, Melbourne, Australia. 2013.
Chow W.S., Xu A., Woo Y.C., Tso A.W.K., Cheung C.W.S., Fong H.Y., Tse H.F., Chau M.T., Cheung B.M.Y. and Lam K.S.L., Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arterioscler Thromb Vasc Biol . 2013, 33: 2454-9.
Shiu S.W.M., Xiao S., Wang Y., Chow W.S., Lam K.S.L. and Cheung B.M.Y., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clin Sci (Lond). 2014, 126: 175-81.
Yeung C.Y., Hui Y.L.E., Lam T.H., Chow W.S., Woo Y.C., Fong H.Y., Xu A., Cheung B.M.Y. and Lam K.S.L., Plasma fibrinogen level as a predictor of incident metabolic syndrome in a community-based prospective study in Hong Kong Chinese, European Association for the Study of Diabetes. 2013.
Yuen M., Tam S., Fong C., Chow W.S., Tan K.C.B. and Lam K.S.L., Cerebrotendinous Xanthomatosis in Seven Hong Kong Chinese., 16th International Congress of Endocrinology & the Endocrine Society's 96th Annual Meeting in Chicago, USA.. 2014.


Researcher : Choy CBY

List of Research Outputs

Yap Y.H.D., Choy C.B.Y., Mok M.M., Wong T.K. and Chan D.T.M., Burkholderia cepacia-an uncommon cause of exit-site infection in a peritoneal dialysis patient, Peritoneal Dialysis International. 2014, 34(4): 471-472.


Researcher : Chu JYS

List of Research Outputs

Lee T.O., NG Y.L.S., Chu J.Y.S., SEKAR R., Harikumar K.G., Miller L.J. and Chow B.K.C., Transmembrane peptides as unique tools to demonstrate the in vivo action of GPCR hetero-complex of secretin and angiotensin, The 7th AOSCE Intercongress, Keelung, Taiwan. 2014.
Lee T.O., NG Y.L.S., Chu J.Y.S., SEKAR R., Harikumar K.G., Miller L.J. and Chow B.K.C., Transmembrane peptides as unique tools to demonstrate the in vivo action of a cross-class GPCR heterocomplex, FASEB Journal. 2014, 28(6): 2632-2644.


Researcher : Chu LW

Project Title:A dementia outreach programme in Central, Western and Southern districts of Hong Kong
Investigator(s):Chu LW, Lam KSL, Lee PWH
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2003


List of Research Outputs

Chan F.H., Chan T.C.I., Hung I.F.N., Luk J.K.H., Chu L.W., Ng W.C., Law T.C. and Cheng V.C.C., Early Identification of an Influenza Outbreak in a Nursing Home with High Vaccination Coverage Facilitates Implementation of Infection-Control Measures and Prevents Spreading of Influenza Infection, Journal of American Medical Directors Association. 2014, 15(4): 300-1.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Efficacy of trivalent seasonal influenza vaccination in reducing mortality and hospitalization in Chinese nursing home older adults, Journal of the American Medical Directors Association . 2013, 14: 889-894.
Chan T.C.I., Luk J.K.H., Chan F.H.W., Chu L.W. and Hung I.F.N., Factors Associated with Seasonal Influenza Vaccination in Chinese Nursing Home Older Adults , Journal of the American Medical Directors Association . 2013, 14(10): 772-774.
Chan T.C.I., Hung I.F.N., Chan K.H., Li P.Y., Li T.W., Luk J.K.H., Chu L.W. and Chan F.H.W., Immunogenicity and Safety of Intradermal Trivalent Influenza Vaccination in Nursing Home Older Adults: A Randomized Controlled Trial., Journal of American Medical Directors Association. 2014.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Inadequate Knowledge of Pneumococcal Vaccine of Nursing Home Healthcare Workers Affects the Pneumococcal Vaccination Uptake of Older Adults in Nursing Homes , Journal of the American Geriatrics Society . 2013, 61(8): 1429-1430.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Predictor of Recurrent Hospitalization in Older Adults?, Journal of the American Medical Directors Association . 2013, 14(9): 706-707.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Risk Factor of Mortality in Chinese Older Adults?, Journal of the American Geriatrics Society . 2013, 61(8): 1430-1432.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Prevalence of Influenza Vaccination and Associated Factors in Chinese Nursing Home Healthcare Workers, Journal of the American Geriatrics Society . 2013, 61(10): 1824-1827.
Chu L.W., So J.C., Wong L.C., Luk J.K.H., Chiu P.K.C., Chan S.Y., Kwan S.M., Chau J., Hui E., Woo J. and McGhee S., Community end-of-life care among Chinese older adults living in nursing homes, Geriatrics & Gerontology International. 2014, 14(2): 273-84.
Chu L.W., Ng K.H.Y., Law A.C.K., Lee A.M. and Kwan F., Validity of the Cantonese Chinese Montreal Cognitive Assessment in Southern Chinese, Geriatrics & Gerontology International. 2014, n/a-n/a.
Gao J., Cheung R.T.F., Chan Y.S., Chu L.W., Mak H.K.F. and Lee T.M.C., The relevance of short-range fibers to cognitive efficiency and brain activation in aging and dementia., PLoS ONE. 2014, 9(4): e90307.
Lee T.M.C., Sun D., LEUNG M.K., Chu L.W. and Keysers C., Neural activities during affective processing in people with Alzheimer’s disease, In: Paul D. Coleman, PhD, Neurobiology of Aging. 2013, 34: 706-715.
Mak H.K.F., Qian W., Ng K.S., Chan Q., Song Y., Chu L.W. and Yau K.K., Combination of MRI hippocampal volumetry and arterial spin labeling MR perfusion at 3-Tesla improves the efficacy in discriminating Alzheimer's disease from cognitively normal elderly adults, In: George Perry, Journal of Alzheimer's Disease. IOS Press, 2014, 41: 749-758.
Shea Y.F., Li L.F., Leung G.K.K. and Chu L.W., An uncommon complication of a fall in the elderly: interhemispheric subdural hematoma, Journal of Clinical Gerontology and Geriatrics. 2013, 4(3): 93-95.
Shea Y.F., Chu L.W., Zhou L., Li W.M., Lin O.Y., Chan M.N.Y., Xu A., Wong L.C., Ho T.Y. and Liu K.W., Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Chinese Patients: A Pilot Study, American Journal of Alzheimer's Disease and Other Dementias. 2013, 28: 769-775.
Yan E.C.W., Cheng S.T., Tiwari A.F.Y., Fong D.Y.T. and Chu L.W., Family Caregiving for Older Persons with Dementia: Caregiver Sense of Entrapment and its association with Potentially Harmful Behaviors. , International Alzheimer's Disease Conference. 2014.
Zhang L., Cheung R.T.F., Chu L.W. and Mak H.K.F., Zhang L, Cheung RTF, Chu LW, Mak HKF. Structural MRI measures in Alzheimer's disease and effects of ethnicity. , Alzheimer’s Association International Conference, 2013. . 2013.


Researcher : Chung ACK

Project Title:Signaling mechanisms of angiotensin II-induced epithelial-mesenchymal transition in renal tubular epithelial cells
Investigator(s):Chung ACK, Lan HY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2008




Researcher : Chung HY

List of Research Outputs

Lau W.C.S., Au Y.L., Chan Y.Y., Chan Y.T., Chan O.W., Cheung T.T., Chung H.Y., Ho C.T.K., Kowk S.K., Lee W.S., Li W.L., Lui M.S., Mok T.M.Y., Tang L.M., Tsang H.L., Yuen K.Y.C. and Wong R.W.S., Outstanding Team 2014, Hong Kong West Cluster cum Queen Mary Hospital. 2014.
Mok C.C., Tam L.S., Leung M.H., Ying K.Y., To C.H., Lee K.L., Ho L.Y., Yip M.L., Tsui H.S., Chan T.H., Lee K.W., Li E.K., Hong Kong Society of Rheumatology , Chan E.Y., Chan K.H., Chan K.M., Chan K.Y., Chan P.S., Chan Y.K., Chau S.Y., Cheung T.C., Cheung T.T., Chung H.Y., Ho C.T.K., Kun E., Kwok L.W., Kwok M.L., Kwok K., Lam C.K., Lao W.N., Lau W.C.S., Lau Y.L., Lee A.K., Lee T.K., Lee K.K., Lee M.Y., Lee S.S., Lee T.L., Yan T., Leung M.C., Li W.L., Liu H.M., Luk M.C., Ma K.Y., Mak L.W., Mok T.M.Y., Ng K.H., Ng W.L., So H., Sung C.K., Tan R.F., Tang S.K., Wan M.C., Wong C.H., Wong K.C., Man S., Wong P.Y., Wong J., Wong R.W.S., Woo W.S., Young K.Y., Yim C.W., Yu K.L., Yuen K.Y.C. and Yung K.M., Referral strategy for early recognition of axial spondyloarthritis: consensus recommendations from the Hong Kong Society of Rheumatology., Int J Rheum Dis. 2013, 16(5): 500-8.


Researcher : Epstein R

List of Research Outputs

Chiu J.W.Y., Tang Y.F., Leung R.C.Y., Wong H.Y.H., Chu K.W., Poon T.C.J., Epstein R. and Yau T.C.C., Efficacy and Tolerability of Adjuvant Oral Capecitabine plus Intravenous Oxaliplatin (XELOX) in Asian patients with Colorectal Cancer: 4-Year Analysis, Asia Pacific Journal of Cancer Prevention. 2013, 14: 6585-6590.


Researcher : FENG Y

List of Research Outputs

FENG Y. and Cheung R.T.F., Neuroprotective effects of melatonin and calpeptin in a rat model of focal cerebral ischemia, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 18.


Researcher : Feng Z

Project Title:30th Annual Meeting of the Society for Neuroscience Identifying and Cloning of B218 Gene, which was Down Regulated by Kainic Acid Treatment and in the Developmental Stages
Investigator(s):Feng Z
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2000




Researcher : Fong HY

List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Chow W.S., Yuen M.M.A., Lee P.C.H., Woo Y.C., Tso A.W.K., Xu A., Fong H.Y., Cheung B.M.Y. and Lam K.S.L., Circulation fibroblast growth factor 21 levels predict incident hyperglycaemia in Chinese subject without the metabolic syndrome, IDF World Diabetes Congress, 2-6 Dec 2013, Melbourne, Australia. 2013.
Chow W.S., Xu A., Woo Y.C., Tso A.W.K., Cheung C.W.S., Fong H.Y., Tse H.F., Chau M.T., Cheung B.M.Y. and Lam K.S.L., Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arterioscler Thromb Vasc Biol . 2013, 33: 2454-9.
Lam K.S.L., Hui Y.L.E., Yuen M.A.M., Yeung C.Y., Woo Y.C., Fong H.Y. and Xu A., Circulating fibroblast growth factor 21 level predicts the progression of diabetes nephropathy in patients with type 2 diabetes, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo, 17-24 Jun 2014, Chicago, USA.. 2014.
Yeung C.Y., Hui Y.L.E., Lam T.H., Chow W.S., Woo Y.C., Fong H.Y., Xu A., Cheung B.M.Y. and Lam K.S.L., Plasma fibrinogen level as a predictor of incident metabolic syndrome in a community-based prospective study in Hong Kong Chinese, European Association for the Study of Diabetes. 2013.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.


Researcher : Fung JYY

List of Research Outputs

Chen D.S., Chen P.J., Lu S.N., Yang P.M., Sung J., Lai C.L., Fung J.Y.Y., Bae S.H., Lee J.S., Kim H.S., Ahn S.H., Yoon G.H., Tanaka J., Wakita T., Aizaki H., Yonezawa A., Lino Y., Abe Y., Ward J., Lou L., Gore C., Mohamed R., Locarnini S., Wallace J., Wait S. and Johnston J., Report from a Viral Hepatitis Policy Forum on implementing the WHO Framework for Global Action on viral hepatitis in North Asia, Journal of hepatology : the journal of the European Association for the Study of the Liver. 2013, 59(5): 1073-80.
Chok K.S.H., Cheung T.T., Lo C.L.R., Chu S.K.F., Tsang S.H.Y., Chan A.C.Y., Sharr W.W., Fung J.Y.Y., Dai W.C., Chan S.C., Fan S.T. and Lo C.M., Pilot study of high-intensity focused ultrasound ablation as a bridging therapy for hepatocellular carcinoma patients wait-listed for liver transplantation, Liver Transplantation. 2014, Epub on 2014-04-18.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Tsang S.H.Y., Fung J.Y.Y., Poon R.T.P., Fan S.T. and Lo C.M., Good longterm survival after primary living donor liver transplantation for solitary hepatocellular carcinomas up to 8 cm in diameter, HPB (Oxford). 2014, Epub on 2014-01-28.
Dai W.C., Chan S.C., Chok K.S.H., Cheung T.T., Sharr W.W., Chan A.C.Y., Fung J.Y.Y., Wong C.L.T. and Lo C.M., Retransplantation using living-donor right-liver grafts, Journal of Hepato-Biliary-Pancreatic Sciences. 2014, Epub on 2014-02-18.
Fung J.Y.Y., Achieving The Best Outcome in HCV for Patients, APASL Conference Janssen Satellite Symposium (Brisbane). 2014.
Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Defining Normal Liver Stiffness Range in a Normal Healthy Chinese Population without Liver Disease, PLoS One. 2013, 8(12): e85067.
Fung J.Y.Y., Seto W.K.W., Lai C.L. and Yuen R.M.F., Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment, Journal of Gastroenterology and Hepatology. Blackwell Publishing, 2014, 29(3): 428-434.
Fung J.Y.Y., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Hepatitis B surface antigen levels after hepatitis B e-antigen seroclearance: a longitudinal follow-up study, Liver Int. 2014.
Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Lai C.L. and Yuen R.M.F., High Prevalence of Non-Alcoholic Fatty Liver Disease in the Chinese - Results from the Hong Kong Liver Health Census, Liver Int. 2014.
Fung J.Y.Y., Lo C.L.R., Chan S.C., Chok K.S.H., Sharr W.W., Dai W.C., Cheung T.T., Chan A.C.Y., Wong C.L.T., Ng I.O.L., Yuen R.M.F. and Lo C.M., Histological outcome after liver transplantation for chronic hepatitis B using oral antiviral therapy alone without hepatitis B immune globulin, The 2014 Joint International Congress of ILTS, ELITA & LICAGE. 2014.
Fung J.Y.Y., Lai C.L., Wong D.K.H., Seto W.K.W., Kopaniszen M. and Yuen R.M.F., Level of hepatitis B surface antigen and not HBV DNA level after HBeAg seroclearance is predictive of HBsAg seroclearance, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S259.
Fung J.Y.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Spontaneous hepatitis B e-antigen seroconversion without subsequent antiviral therapy is associated with higher rates of hepatitis B surface antigen seroclearance, Annual Meeting, American Association for the Study of Liver Disease. 2013.
Fung J.Y.Y., Poon R.T.P., Yu W.C., Chan S.C., Chan A.C.Y., Chok K.S.H., Cheung T.T., Seto W.K.W., Lo C.M., Lai C.L. and Yuen R.M.F., Use of liver stiffness measurement for liver resection surgery: correlation with indocyanine green clearance testing and post-operative outcome, PLoS One. 2013, 8(8): e72306.
Huang F.Y., Wong D.K.H., Seto W.K.W., Zhang A.Y., Lee C.K., Lin C.K., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Sequence Variations of Full-Length Hepatitis B Virus Genomes in Chinese Patients with HBsAg-Negative Hepatitis B Infection, PLoS One. 2014, 9(6): e99028.
Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.
Lam Y.F., Wong D.K.H., Seto W.K.W., To K.K.W., Hung I.F.N., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., HLA-DP and interferon gamma receptor-2 gene variants and their association with viral hepatitis activity in chronic hepatitis B infection., Journal of Gastroenterology and Hepatology. 2014, 29(3): 533-539.
Seto W.K.W., Lam Y.F., Fung J.Y.Y., Wong D.K.H., Huang F.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after five years of entecavir treatment, J Gastroenterol Hepatol. 2013, 29(5): 1028-34.
Seto W.K.W., Lam Y.F., Liu S.H.K., Mak L.Y., Ko K.L.M., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Continuous Entecavir for Treatment-Naïve Chinese Chronic Hepatitis B in the Real World Setting: The Six-Year Results, Digestive Diseases Week 2014. Gastroenterology. 2014, 146(5): Suppl 1: S963-4.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing hematopoietic stem cell transplant: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing rituximab-containing chemotherapy: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Liu K.S.H., Lai C.L. and Yuen R.M.F., Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B, Clinical Microbiology and Infection. 2014.
Seto W.K.W., Tanaka Y., Shinkai N., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Performance of a highly sensitive hepatitis B surface antigen assay among chronic hepatitis B patients after hepatitis B surface antigen seroclearance, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014. (Absno. 208). Hepatology International. 2014, 8(S1): S69.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Lai C.L. and Yuen R.M.F., Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy, Hepatology. 2013, 58(3): 923-31.
Seto W.K.W., Tsang O.T., Liu K., Chan J.M., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection, Journal of Viral Hepatitis. 2013, 20(7): 470-7.
Wong C.L.T., Fung J.Y.Y., Chok K.S.H., Cheung T.T., Chan A.C.Y., Dai W.C., Chan S.C., Poon R.T.P. and Lo C.M., Post liver transplant hepatitis B booster vaccination in chronic hepatitis B recipients with prior immune response (Poster presentation), Joint International Congress of ILTS, ELITA & LICAGE, London, United Kingdom, 4-7 June 2014.
Wong C.L.T., Fung J.Y.Y. and Lo C.M., Prevention of recurrent hepatitis B infection after liver transplantation, Hepatobiliary & Pancreatic Diseases International. 2013, 12(5): 465-472.
Wong D.K.H., Tsoi Y.Y.O., Huang F.Y., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Application of co-amplification at lower denaturation temperature-PCR (COLD-PCR) sequencing for the early detection of antiviral drug resistance mutations of hepatitis B virus, Journal of Clinical Microbiology. 2014.
Wong D.K.H., LIN S.C., Huang F.Y., Tsoi Y.Y.O., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Association of methylated histones and DNA methylases with hepatitis B virus covalently closed circular DNA and their association with hepatitis B virus replication, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S214.
Wong D.K.H., Kopaniszen M., Omagari K., Tanaka Y., Fong D.Y.T., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Zhang A.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Effect of Hepatitis B Virus Reverse Transcriptase Variations on Entecavir Treatment Response, Journal of Infectious Diseases. 2014.
Wong D.K.H., Fung J.Y.Y., Lee C.K., Seto W.K.W., Leung J., Huang D.K.H., Lin C.K., Lai C.L. and Yuen R.M.F., Hepatitis B virus serological and virological activities in blood donors with occult hepatitis B, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 868). Hepatology International. 2014, 8(S1): S149.
Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.
ZHANG A., Wong D.K.H., Huang F.Y., Fung J.Y.Y., Seto W.K.W., Poon R.T.P., Lai C.L. and Yuen R.M.F., Characterization of intrahepatic HBV quasispecies genetic variability within the pre-S region in patients with HBV-related hepatocellular carcinoma, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Zheng M.H., Seto W.K.W., Shi K.Q., Wong D.K.H., Fung J.Y.Y., Hung I.F.N., Fong D.Y.T., Yuen J.C.H., Tong T., Lai C.L. and Yuen R.M.F., Artificial neural network accurately predicts hepatitis B surface antigen seroclearance, PLoS One. 2014, 9(6): e99422.


Researcher : Fung TK

List of Research Outputs

Zhang M.Y., Fung T.K., Chen F.Y. and Chim J.C.S., Methylation Profiling of SOCS1, SOCS2, SOCS3, CISH and SHP1 in Philadelphia-negative (Ph-ve) Myeloproliferative Neoplasm (MPN), Journal of Cellular and Molecular Medicine. 2013, 17(10): 1282-90.


Researcher : GUO Y

List of Research Outputs

Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.
Guo Y., Chung S.K., Siu D.C.W., Kwan S.C., Ho W.L., Yeung P.K.K., Teo K.C. and Chan K.H., Endothelin-1 overexpression exacerbate experimental allergic encephalomyelitis, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong. 2014.
Ma C.H., SHI X., HE B., GUO Y., Wong N.S.M. and Leung A.Y.H., A novel role of Inka1 in regulating zebrafish hematopoiesis, 7th Zebrafish Disease Models Conference. 2014.


Researcher : Gao J

Project Title:The relevance of brain connectivity in resting, alert and meditation states: a concurrent EEG/fMRI study
Investigator(s):Gao J, Sik HH, Hung YS
Department:Centre of Buddhist Studies
Source(s) of Funding:Small Project Funding
Start Date:06/2013


List of Research Outputs

Gao J., Cheung R.T.F., Chan Y.S., Chu L.W., Mak H.K.F. and Lee T.M.C., The relevance of short-range fibers to cognitive efficiency and brain activation in aging and dementia., PLoS ONE. 2014, 9(4): e90307.


Researcher : Gu P

List of Research Outputs

Hui X., Gu P., Lam K.S.L. and Xu A., SIRT1 antagonizes obesity-induced vascular dysfunction via its actions in PVAT, 14th International Conference of Obesity. 2014.
Hui X., Gu P., Lam K.S.L., Vanhoutte P.M.G.R. and Xu A., SIRT1 modulates white/brown switch in PVAT, 8th Singapore Diabetes Forum. 2014.


Researcher : Guo Y

List of Research Outputs

Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.
Guo Y., Chung S.K., Siu D.C.W., Kwan S.C., Ho W.L., Yeung P.K.K., Teo K.C. and Chan K.H., Endothelin-1 overexpression exacerbate experimental allergic encephalomyelitis, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong. 2014.
Ma C.H., SHI X., HE B., GUO Y., Wong N.S.M. and Leung A.Y.H., A novel role of Inka1 in regulating zebrafish hematopoiesis, 7th Zebrafish Disease Models Conference. 2014.


Researcher : HAN L

List of Research Outputs

Ho J.C.M., Au W.Y., HAN L., Kwong Y.L. and Ip M.S.M., Effect of therapeutic arsenic exposure on pulmonary function, Respiratory medicine. 2013, 107(9): 1423-1430.


Researcher : HAN Q

List of Research Outputs

HAN Q., Yeung S.C., Ip M.S.M. and Mak J.C.W., Cellular mechanisms in intermittent hypoxia-induced cardiac damage in vivo, J Physiol Biochem. Springer, 2014, 70: 201-213.
HAN Q., Yeung S.C., Ip M.S.M. and Mak J.C.W., Intermittent hypoxia-induced NF-kB and HO-1 regulation in human endothelial EA.hy926 cells, Cell Biochem. Biophys.. 2013, 66: 431-441.


Researcher : HE B

List of Research Outputs

HE B., SHI X., Man C.H., Ma C.H., Ekker S.C., Chow C.H., So C.W., Choi W.L., Zhang W., Zhang Y. and Leung A.Y.H., Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia., Blood. USA, American Society of Hematology, 2014, 123: 2518-2529.
Ma C.H., SHI X., HE B., GUO Y., Wong N.S.M. and Leung A.Y.H., A novel role of Inka1 in regulating zebrafish hematopoiesis, 7th Zebrafish Disease Models Conference. 2014.


Researcher : HUANG Z

List of Research Outputs

Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
KONG K.Y., Tang V.H.M., Pan K., HUANG Z., LEE T.H.J., Hinnebusch A., Jin D. and Wong C.M., Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing, Nucleic Acids Research. Oxford Journals, 2014, 42: 643-660.


Researcher : Ho CTK

List of Research Outputs

Lau W.C.S., Au Y.L., Chan Y.Y., Chan Y.T., Chan O.W., Cheung T.T., Chung H.Y., Ho C.T.K., Kowk S.K., Lee W.S., Li W.L., Lui M.S., Mok T.M.Y., Tang L.M., Tsang H.L., Yuen K.Y.C. and Wong R.W.S., Outstanding Team 2014, Hong Kong West Cluster cum Queen Mary Hospital. 2014.
Mok C.C., Tam L.S., Leung M.H., Ying K.Y., To C.H., Lee K.L., Ho L.Y., Yip M.L., Tsui H.S., Chan T.H., Lee K.W., Li E.K., Hong Kong Society of Rheumatology , Chan E.Y., Chan K.H., Chan K.M., Chan K.Y., Chan P.S., Chan Y.K., Chau S.Y., Cheung T.C., Cheung T.T., Chung H.Y., Ho C.T.K., Kun E., Kwok L.W., Kwok M.L., Kwok K., Lam C.K., Lao W.N., Lau W.C.S., Lau Y.L., Lee A.K., Lee T.K., Lee K.K., Lee M.Y., Lee S.S., Lee T.L., Yan T., Leung M.C., Li W.L., Liu H.M., Luk M.C., Ma K.Y., Mak L.W., Mok T.M.Y., Ng K.H., Ng W.L., So H., Sung C.K., Tan R.F., Tang S.K., Wan M.C., Wong C.H., Wong K.C., Man S., Wong P.Y., Wong J., Wong R.W.S., Woo W.S., Young K.Y., Yim C.W., Yu K.L., Yuen K.Y.C. and Yung K.M., Referral strategy for early recognition of axial spondyloarthritis: consensus recommendations from the Hong Kong Society of Rheumatology., Int J Rheum Dis. 2013, 16(5): 500-8.


Researcher : Ho JCM

Project Title:MERIT – A phase II marker identification trial for TarcevaTM in second line NSCLC patients
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:F Hoffmann-La Roche and Co. Ltd. - General Award
Start Date:07/2005


Project Title:A Phase III, radonmized, double-blinded, parallel group, multi centre study to access the efficacy and safety of ZD6474 (ZACTIMA TM) in combination with pemetrexed (Alimta) versus pemetrexed alone in patients with locally-advanced or metastatic (stage IIIB or IV) non-small cell lung cancer (NSCLC) after failure of 1st line anti-cancer therapy
Investigator(s):Ho JCM, Wong KYM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:02/2007


Project Title:A rabdomized, double blind, placebo controlled, phase IIIB trial comparing bevacizumab therapy with or without erlotinib after completion of chemotherapy with bevacizumab for the first line treatment of locally advanced, recurrent, or metastatic non-small cell lung cancer
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:08/2007


Project Title:The effect of inhaled corticosteroids on the risk of diabetes, impaired glucose tolerance and characteristics of glucose regulation in adults with asthma: a population based matched controlled study
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:Lee Wing Tat Fund
Start Date:08/2007


Project Title:A Phase 3, multicentre, randomized, placebo-controlled, double-bind trial of AMG 706 in combination with paclitaxel and carboplatin for advanced non-small cell lung cancer
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:11/2007


Project Title:A phase III, randomized, double-blind, active-controlled, parallel-group study, conducted under in-house building conditions, to examine the safety, tolerability, and efficacy of a single dose of intravenous MK-0517 for the prevention of chemotherapy-induced nausea and vomiting (CINV) associated wtih Cisplatin chemotheray
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:06/2008


Project Title:A randomized, multicenter phase II study to explore whether biomarkers correlate with treatment outcome in chemo-naive patients with advanced or recurrent non-squamous non-small cell lung cancer, who receive treatment with bevacizumab (at a dose of either 7,5mg.kg or 15mg/kg) in addition to carboplain-based chemotherapy (gemcitabine or paclitaxed)
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:12/2008


Project Title:In-vitro combination of arsenic trioxide and chemotherapy in non-small cell lung cancer
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:Hong Kong Lung Foundation Research Grant
Start Date:02/2009


Project Title:A randomised, placebo-controlled, double-blind phase III study of sequential administration of Tarceva (erlotinib) or placebo in combination with gemcitabine/platinum as first-line treatment in patients with stage IIIB/V non-small cell lung cancer (NSCLC)
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:04/2009


Project Title:Multicenter, randomized, double-blind, phase III trial to investigate the efficacy and safety of oral BIBF 1120 plus standard pemetrexed therapy compared to placebo plus standard pemetrexed therapy in patients with stage IIIB/IV or recurrent non small cell lung cancer after failure of first line chemotherapy
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:04/2009


Project Title:A Phase III, multi-center, placebo–controlled trial of Sorafenib (BAY 43-9006) in patients with relapsed or refractory advanced predominantly non squamous Non-Small Cell Lung Cancer (NSCLC) after 2 or 3 previous treatment regimens.
Investigator(s):Ho JCM, Lam CLD, Lam CMJ, Wang KLJ, Wong KYM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:08/2009


Project Title:Phase 2, open-label single arm study of the efficacy and safety of PF 02341066 in patients with advanced non-small cell lung cancer (NSCLC) harboring a translocation or inversion involving the anaplastic lymphoma kinase (ALK) gene locus
Investigator(s):Ho JCM, Lam CLD, Wong KYM, Lam CMJ, Ip MSM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:04/2010


Project Title:Phase 3, randomized, open-label study of the efficacy and safety of PF-02341066 versus standard of care chemotherapy (pemetrexed or docetaxel) in patients with advanced nonsmall cell lung cancer (NSCLC) harbouring a translocation or inversion event involving the anaplastic lymphoma kinase (ALK) gene locus
Investigator(s):Ho JCM, Lam CLD, Wong KYM, Lam CMJ, Ip MSM
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:04/2010


Project Title:Randomized controlled trial of S-1 versus docetaxel in patients with non-small cell lung cancer who have received a platinum-based treatment
Investigator(s):Ho JCM, Lam CLD
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:08/2010


Project Title:In-vitro combination of arsenic trioxide and chemotherapy in non-small cell lung cancer
Investigator(s):Ho JCM
Department:Medicine
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:03/2011


Project Title:A Randomized, Double-Blind, Phase 2 Study of erlotinib (Tarceva®) in combination with OSI 906 or placebo in Chemonaive Patients with Advanced NSCLC with Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) Gene
Investigator(s):Ho JCM, Lam CLD
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:04/2011


Project Title:Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab in Addition to Paclitaxel and Carboplatin versus Placebo in Addition to Paclitaxel and Carboplatin in Subjects with Stage IV/Recurrent Non-Small Cell Lung Cancer (NSCLC)
Investigator(s):Ho JCM, Lam CLD
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:05/2011


Project Title:In vitro study of arsenic trioxide in treatment of malignant pleural mesothelioma
Investigator(s):Ho JCM, Lam SK
Department:Medicine
Source(s) of Funding:Pneumoconiosis Compensation Fund Board - General Award
Start Date:07/2011


Project Title:A Phase III Randomised, Double blind, Placebo controlled, Parallel, Multicentre Study to Assess the Efficacy and Safety of continuing IRESSATM 250 mg in addition to Chemotherapy versus Chemotherapy alone in Patients who have Epidermal Growth Factor Receptor (EGFR)Mutation Positive Locally advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) and have progressed on First Line IRESSATM
Investigator(s):Ho JCM, Lam CLD
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:02/2012


List of Research Outputs

Chen H., Ma C.H., Cao K., Ho J.C.M., Ziea E., Wang V.T. and Zhang Z., A Systematic Review and Meta-Analysis of Herbal Medicine on Chronic Obstructive Pulmonary Diseases, Evidence-Based Complementary and Alternative Medicine. 2014, 2014: 925069.
Cho S.H., David-Wang A., Ho J.C.M., Jeong W.J., Liam C.K., Lin J.T., Muttalif A.R., Perng D.W., Tan T.L., Yunus F. and Neira G., Discrepancy between patient-perception and guideline-defined asthma control in Asia: a survey of over 2400 patients, Respiratory Effectiveness Group (REG) Summit, London, UK, 28-29 June. 2014.
Ho J.C.M., Anti-angiogenesis therapy in lung cancer: a practical approach, Hong Kong Journal of Radiology. 2013, 16 (Suppl): S55-59.
Ho J.C.M., Au W.Y., HAN L., Kwong Y.L. and Ip M.S.M., Effect of therapeutic arsenic exposure on pulmonary function, Respiratory medicine. 2013, 107(9): 1423-1430.
Ho J.C.M., Tam C.C.T. and Lam S.K., Personalized Treatment of Lung Adenocarcinoma, Clinical Pulmonary Medicine. 2013.
Ho J.C.M., Tam C.C.T. and Lam S.K., Salvage Therapy Beyond Targeted Therapy in Lung Adenocarcinoma, Seminars in Respiratory and Critical Care Medicine. 2013.
LI Y., Lam S.K., ZHENG C. and Ho J.C.M., The Role of Autophagy Induced by Tyrosine Kinase Inhibitors in Non-small Cell Lung Carcinoma, 15th World Conference on Lung Cancer. 2013.
LI Y., Lam S.K., ZHENG C. and Ho J.C.M., The Role of Autophagy Induced by Tyrosine Kinase Inhibitors in Non-small Cell Lung Carcinoma, 20th Hong Kong International Cancer Congress. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo , 15th World Conference on Lung Cancer. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo , 20th Hong Kong International Cancer Congress. 2013.
Lam S.K., Mak J.C.W., ZHENG C., LI Y., Kwong Y.L. and Ho J.C.M., Downregulation of thymidylate synthase with arsenic trioxide in lung adenocarcinoma, International Journal of Oncology. 2014, 44: 2093-2102.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Dual Action of Arsenic Trioxide on Thymidylate Synthase and Apoptosis in Mesothelioma , Conference on joining hands to eliminate asbestos hazards. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Dual action of arsenic trioxide on thymidylate synthase and apoptosis in mesothelioma, Conference on joining hands to eliminate asbestos hazards, Pneumoconiosis Compensation Fund Board, Hong Kong. 2013.
Lee C.H., Brown C., Gralla R., Hirsh V., Thongprasert S., Tsai C.M., Tan E.H., Ho J.C.M., Chu D.T., Zaatar A., Sanchez J.O., Vu V.V., Au J.S.K., Inoue A., Lee S.M., Gebski V. and Yang J.C.H., Impact of epidermal growth factor receptor inhibitor in non-small cell lung cancer on progression-free an overall survival: a meta-analysis, Journal of the National Cancer Institute. 2013, 105(9): 595-605.
Mak J.C.W., Ho S.P., Ho A.S., Law B.K., Cheung A.H.K., Ho J.C.M., Ip M.S.M. and Chan M.M.W., Sustained elevation of systemic oxidative stress and inflammation in exacerbation and remission of asthma, ISRN Allergy. 2013, 561831.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100: 459-463.e1.
Tam T.C., Ho J.C.M., Wong M.K., Wong W.M., Wang J.K., Lam J.C., Lui M.M., Lam W.K., Ip M.S.M. and Lam C.L.D., Treatment Outcomes in Elderly with Advanced-stage Non-small Cell Lung Cancer, LUNG. Springer, 2013, 191: 645 - 654.
Thompson P., Salvi S., Lin J., Cho Y.J., Eng P., Manap R.A., Boonsawat W., Hsu J.Y., Faruqi R.A., Moreno-Cantu J.J., Fish J.E. and Ho J.C.M., Insights, attitudes,and perceptions about asthma and its treatment: Findings from a multinational survey of patients from 8 Asia-Pacific countries and Hong Kong, Respirology. 2013, 18(6): 957-967.
Wu Y.L., Lee J.S., Thongprasert S., Yu C.J., Zhang L., Ladrera G., Srimuninnimit V., Sriuranpong V., Sandoval-Tan J., Zhu Y., Liao M., Zhou C., Pan H., Lee V.H.F., Chen Y.M., Sun Y., Margono B., Fuerte F., Chang G.C., Seetalarom K., Wang J., Cheng C.K., Syahruddin E., Qian X., Ho J.C.M., Kurnianda J., Liu H.E., Jin K., Truman M., Bara I. and Mok T., Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-lung cancer (FASTACT-2): a randomised, double-blind trial, Lancet Oncology. Science Direct, 2013, 14: 777-786.
ZHENG C., Lam S.K., LI Y., Fong B.M., Mak J.C.W. and Ho J.C.M., Combination of arsenic trioxide and chemotherapy in small cell lung cancer, Lung Cancer. 2013, 82(2): 222-230.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, 15th World Conference on Lung Cancer. 2013.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, 20th Hong Kong International Cancer Congress. 2013.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, Journal of Thoracic Oncology. 2013, 8: S1041.


Researcher : Ho JCY

List of Research Outputs

Lo C.Y., Tjong Y.W., Ho J.C.Y., Siu D.C.W., Yue S., Tse H.F. and Yao X., An upregulated expression of vanilloid transient potential channels 2 enhances the hypo-osmolarity induced cytosolic calcium elevation in human induced pluripotent stem cells model of Hutchinson-Gillford Progeria Syndrome., PloS One. 2014, 9: e87273.
ZHANG J., Ho J.C.Y., Chan Y.C., Lian Q., Siu D.C.W. and Tse H.F., Overexpression of myocardin induces partial transdifferentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells into cardiomyocytes, Physiological Reports. 2014, 2: n/a-n/a.


Researcher : Ho SL

Project Title:Biochemical markers in a large Chinese kindred with autosomal dominant motor neurone disease associated with SOD1 mutation
Investigator(s):Ho SL, Song Y, Wang Y
Department:Medicine
Source(s) of Funding:Liu Po Shan/Dr Vincent Liu Endowment Fund for Motor Neuron diseases - General Award
Start Date:04/2007


Project Title:Pathophysiological study of Parkinson's disease associated with leucine-rich repeat kinase 2 (LRRK2) gene mutation
Investigator(s):Ho SL, Ho WL, Siu DCW
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


List of Research Outputs

Ho S.L., Associate Editor, Clinical Neuropharmacology. USA, Lippincott Williams&Wilkins, 2014.
Ho S.L., Editorial Board Member, Brain and Behavior. USA, John Wiley & Sons Inc, 2014.
Ho S.L., Editorial Board Member, Clinical Neuropharmacology. USA, Lippincott Williams & Wilkins, 2013.
Ho S.L., Editorial Board Member, Clinical Neuropharmacology. USA, Lippincott Williams & Wilkins, 2014.
Ho S.L., Invited Speaker, Mitochondrial and synaptic dysfunction: implications for Parkinson’s disease , 5th East Asia Neurology Forum, Kaohsiung, Taiwan . Taiwan, 2014.
Ho S.L., Invited Speaker, Outreach Trip by HKU to National Institute of Mental Health and Neurosciences, Bangalore, India. Bangalore, India, 2013.
Ho S.L., Section Editor, Translational Neruodegeneration. UK, BioMed Central, 2014.
Ho W.L., Tse H.M., Liu H., Lu S., Ho W.M., Kung M.H.W., Ramsden D.B. and Ho S.L., Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System, PLoS ONE. 2013, 8(9): e74065.
LI T.H., Yao N., Chua S.E., Ho S.L., Khong P.L. and Mak H.K.F., Li DTH, Yao N, Chua S, Ho SL, Khong PL, Mak HKF. Brain Iron Deposition in Parkinson’s Disease by High Resolution Susceptibility MR Phase Imaging. , 20th World Congress of Parkinson's Disease. 2013.
Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon S.F.K., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality, PLoS One. 2014, 9(2): e88283.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S., Hon S.F., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality., Plos One . 2014, 11:9(2): e882883.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon F.K.S., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with cancer are at increased risk of recurrent stroke and cardiovascular mortality, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chan Y.H., Teo K.C., Chan K.H., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases – Relationships and comparisons with vascular markers of atherosclerosis, Atherosclerosis. 2014, 235(1): 230-235.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang R.S., Teo K.C., Hon S.F., Chan K.H., Wat K.L., Cheung R.T., Li L.S., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lau G.K.K., Wong Y.K., Chang R.S.K., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, European Journal of Neurology. 2014, 21(2): 319-325.
Lee C.Y., Lam C.L.D., Chang S.K.R., Pang Y.Y., Chang C., Lau G.K.K., Teo K.C., Ho S.L., Cheung R.T.F. and Chan K.H., Prognosis and Crisis in Generalised Myasthenia Gravis among Hong Kong Chinese, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.
Lee Y.K., Ho W.L., Schick R., Lau V.Y.M., Lai K.W.H., Zhou T., Li Y., Ng K.M., Ho S.L., Esteban M.A., Binah O., Tse H.F. and Siu D.C.W., Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells., Pflügers Archiv - European Journal of Physiology. 2013.
Liu H., Lu S., Ho W.L., Tse H.M., Pang S.Y.Y., Kung M.H.W., Ho W.M., Ramsden D.B., Zhou Z. and Ho S.L., LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. , Annals of Clinical and Translational Neurology. 2014, 1(3): 199-208.
Liu H., Ho W.L., Tse H.M., Leung C.T.G., Kung M.H.W., Zhou Z., Ramsden D.B. and Ho S.L., Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity , 18th International Congress of Parkinson’s Disease and Movement Disorders, June 2014, sweden.. 2014, 29.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drug resumption after antiplatelet-related intracerebral haemorrhage, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 40.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Siu D.C.W., Leung G.K.K., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drugs resumption after antiplatelet-related intracerebral haemorrhage in Chinese , 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelt drug resumption after antiplatelet-related intracerebral haemorrhage, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Best Free Paper Award (First Runner-up): Antiplatelet Drugs Resumption after Antiplatelet-related Intra-cerebral Haemorrhage, 14th Asian & Oceanian Congress of Neurology. 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intra-cerebral haemorrhage in Hong Kong, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intracerebral hemorrhage in Hong Kong Chinese, Neurological Research. 2014, 36: 143-149.


Researcher : Ho WL

Project Title:Pathogenic mechanism of leucine-rich repeat kinase 2 (LRRK2) R1441G mutation on synaptic mitochondrial dysfunction associated with Parkinson’s disease
Investigator(s):Ho WL, Ho SL, Liu H
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2014


List of Research Outputs

Chan K.H., Lee R., Lee J.C.Y., Tse C.T.A., Pang S.Y.Y., Lau G.K.K., Teo K.C. and Ho W.L., Central nervous system inflammatory demyelinating disorders among Hong Kong Chinese, Journal of Neuroimmunology. 2013, 262: 100-105.
Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.
Guo Y., Chung S.K., Siu D.C.W., Kwan S.C., Ho W.L., Yeung P.K.K., Teo K.C. and Chan K.H., Endothelin-1 overexpression exacerbate experimental allergic encephalomyelitis, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong. 2014.
Ho W.L., Tse H.M., Liu H., Lu S., Ho W.M., Kung M.H.W., Ramsden D.B. and Ho S.L., Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System, PLoS ONE. 2013, 8(9): e74065.
Ho W.L., Functional Studies of Neuronal Mitochondrial Uncoupling Proteins: Implication in Parkinson’s Disease , The 5th East Asia Neurology Forum (EANF), Apr 11-12, 2014, Kaosiung, Taiwan. Organizer: Taiwan Neurological Society. 2014.
Lee Y.K., Ho W.L., Schick R., Lau V.Y.M., Lai K.W.H., Zhou T., Li Y., Ng K.M., Ho S.L., Esteban M.A., Binah O., Tse H.F. and Siu D.C.W., Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells., Pflügers Archiv - European Journal of Physiology. 2013.
Liu H., Lu S., Ho W.L., Tse H.M., Pang S.Y.Y., Kung M.H.W., Ho W.M., Ramsden D.B., Zhou Z. and Ho S.L., LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. , Annals of Clinical and Translational Neurology. 2014, 1(3): 199-208.
Liu H., Ho W.L., Tse H.M., Leung C.T.G., Kung M.H.W., Zhou Z., Ramsden D.B. and Ho S.L., Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity , 18th International Congress of Parkinson’s Disease and Movement Disorders, June 2014, sweden.. 2014, 29.


Researcher : Ho WM

List of Research Outputs

Ho W.L., Tse H.M., Liu H., Lu S., Ho W.M., Kung M.H.W., Ramsden D.B. and Ho S.L., Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System, PLoS ONE. 2013, 8(9): e74065.
Liu H., Lu S., Ho W.L., Tse H.M., Pang S.Y.Y., Kung M.H.W., Ho W.M., Ramsden D.B., Zhou Z. and Ho S.L., LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. , Annals of Clinical and Translational Neurology. 2014, 1(3): 199-208.


Researcher : Hon FKS

List of Research Outputs

Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon F.K.S., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with cancer are at increased risk of recurrent stroke and cardiovascular mortality, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.


Researcher : Hoo RLC

Project Title:Adipocyte-derived small lipid-binding proteins as a mediator of obesity-induced cardiac dysfunction and heart failure
Investigator(s):Hoo RLC, Xu A, Lam KSL
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012
Completion Date:02/2014


Project Title:Interplay between adipocyte fatty acid binding protein and endoplasmic reticulum stress in toxic lipids-induced inflammation in macrophages
Investigator(s):Hoo RLC, Xu A
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:The role of adipocyte fatty acid binding protein in diet-induced obesity
Investigator(s):Hoo RLC, Xu A, Lam KSL
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:Adipocyte fatty acid binding protein (A-FABP) as a potential mediator of cardiac dysfunction and heart failure related to diabetes and obesity
Investigator(s):Hoo RLC, Xia Z, Xu A
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:The pathological role of adipocyte fatty acid binding protein in alcoholic fatty liver disease.
Investigator(s):Hoo RLC, Xu A
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2014


List of Research Outputs

Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte Fatty Acid Binding Protein Potentiates Toxic Lipids-induced Endoplasmic Reticulum Stress Via Inhibition Of JAK2-Dependent Autophagy , 12th International Congress on Obesity (ICO) . 2014.
Hoo R.L.C., SHU L., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein (A-FABP) potentiates toxic lipids-induced endoplasmic reticulum stress via suppression of JAK2-dependent autophagy, 19th Medical Research Conference. 2014.
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein potentiates palmitic acid induced endoplasmic reticulum stress in macrophages via inhibition of Janus kinase 2-dependent autophagy, Singapore Diabetes Forum 2014 . 2014.
Hoo R.L.C., Xu A. and Lam K.S.L., Adipocyte fatty acid binding proten in the pathogenesis of obesity-related nonalcoholic steatohepatitis, Asia-Pacific Diabetes & Obesity Study Group Symposium, 12-13 Oct 2013, Tokyo, Japan. 2013.
Hoo R.L.C., LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and translational (Oral Presentation), 19th Medical Research Conference. 2014.
Zhou M., PAN Y., SHU L., Lam K.S.L., Xu A. and Hoo R.L.C., Adipocyte fatty acid binding protein (A-FABP) is a potential mediator of diabetic cardiomyopathy and ischemic reperfusion induced cardiac injury , Ninth International Symposium on Healthy Aging “Aging with Confidence” . 2014.


Researcher : Hsu ASJ

List of Research Outputs

Leung W.K., Lo O.S.H., Liu K.S., Tong S.M., But Y.K.D., Lam F.Y., Hsu A.S.J., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., Detection of Colorectal Adenoma by Narrow Band Imaging (HQ190) vs. High-Definition White Light Colonoscopy: A Randomized Controlled Trial, Am J Gastroenterol. 2014, 109(6): 855-63.
Liu K.S., Hung I.F.N., Seto W.K.W., Tong S.M., Hsu A.S.J., Lam F.Y., But Y.K.D., Wong S.Y. and Leung W.K., Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial, Gut. 2013.
Liu K.S.H., Hung I.F.N., Seto W.K.W., But Y.K.D., Hsu A.S.J., Tong S.M., Chan K.H., Tan V.P.Y. and Leung W.K., Immune Responses to intramuscular or intradermal trivalent influenza vaccines in patients with inflammatory bowel disease: A randomized controlled trial, Asian Organization for Crohn's and Colitis. 2014.


Researcher : Hu HC

Project Title:A study to validate a symptom severity questionnaire for patents with functional dyspepsia
Investigator(s):Hu HC, Lam CLK
Department:Medicine
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:10/1998




Researcher : Huang FY

Project Title:Role of estorgen-inducible MiR23a in hepatocellular carcinoma
Investigator(s):Huang FY, Wong DKH, Fung JYY, Seto WKW, Lai CL, Yuen RMF
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2014


List of Research Outputs

Huang F.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Estrogen represses anti-apoptotic genes expression via MiR-23a: contribution to sex differences in the development of hepatocellular carcinoma, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 667). Hepatology International. 2014, 8(S1): S243.
Huang F.Y., Wong D.K.H., Seto W.K.W., Zhang A.Y., Lee C.K., Lin C.K., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Sequence Variations of Full-Length Hepatitis B Virus Genomes in Chinese Patients with HBsAg-Negative Hepatitis B Infection, PLoS One. 2014, 9(6): e99028.
Seto W.K.W., Lam Y.F., Fung J.Y.Y., Wong D.K.H., Huang F.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after five years of entecavir treatment, J Gastroenterol Hepatol. 2013, 29(5): 1028-34.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Liu K.S.H., Lai C.L. and Yuen R.M.F., Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B, Clinical Microbiology and Infection. 2014.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Lai C.L. and Yuen R.M.F., Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy, Hepatology. 2013, 58(3): 923-31.
Wong D.K.H., Tsoi Y.Y.O., Huang F.Y., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Application of co-amplification at lower denaturation temperature-PCR (COLD-PCR) sequencing for the early detection of antiviral drug resistance mutations of hepatitis B virus, Journal of Clinical Microbiology. 2014.
Wong D.K.H., LIN S.C., Huang F.Y., Tsoi Y.Y.O., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Association of methylated histones and DNA methylases with hepatitis B virus covalently closed circular DNA and their association with hepatitis B virus replication, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S214.
Wong D.K.H., Kopaniszen M., Omagari K., Tanaka Y., Fong D.Y.T., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Zhang A.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Effect of Hepatitis B Virus Reverse Transcriptase Variations on Entecavir Treatment Response, Journal of Infectious Diseases. 2014.
Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.
ZHANG A., Wong D.K.H., Huang F.Y., Fung J.Y.Y., Seto W.K.W., Poon R.T.P., Lai C.L. and Yuen R.M.F., Characterization of intrahepatic HBV quasispecies genetic variability within the pre-S region in patients with HBV-related hepatocellular carcinoma, Liver Meeting, American Association for the Study of Liver Disease. 2013.


Researcher : Hui CK

Project Title:Significance of occult hepatitis B infection in patients undergoing autologous HSCT
Investigator(s):Hui CK, Liang RHS, Lau G, Lie AKW
Department:Medicine
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:10/2006




Researcher : Hui X

Project Title:Sirt1 in adipocyte as a regulator of adipose tissue senescence and systemic energy homeostasis
Investigator(s):Hui X, Xu A
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2012
Completion Date:10/2013


Project Title:Cell Symposia: Immunometabolism---from Mechanisms to Therapy; Adipose selective disruption of SIRT1 impairs insulin sensitivity via modulation of macrophage infiltration and polarization in mice
Investigator(s):Hui X
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2013


List of Research Outputs

Hui X., Gu P., Lam K.S.L. and Xu A., SIRT1 antagonizes obesity-induced vascular dysfunction via its actions in PVAT, 14th International Conference of Obesity. 2014.
Hui X., Gu P., Lam K.S.L., Vanhoutte P.M.G.R. and Xu A., SIRT1 modulates white/brown switch in PVAT, 8th Singapore Diabetes Forum. 2014.
Li H., Hui X., Yang S., Hu X., Tang X., Li P., Li S., Yang L., Jin S., Wang Y., Xu A. and Wu D., High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pichia pastoris, Protein Expr Purif. 2013, 91: 221-227.
Li H., Hui X., Yang S., Hu X., Tang X., Li P., Li S., Yang L., Jin S. and Wang Y., High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pichia pastoris, Protein Expression and Purification. 2013, 91: 221-227.
Yang S., Kuang Y., Li H., Liu Y., Hui X., Li P., Jiang Z., Zhou Y., Wang Y., Xu A., Li S., Liu P. and Wu D., Enhanced production of recombinant secretory proteins in Pichia pastoris by optimizing Kex2 P1' site., Plos One. 2013, 8: e75347.


Researcher : Hui YLE

Project Title:Genetic markers of severe diabetic retinopathy in Southern Chinese subjects with type 2 diabetes
Investigator(s):Hui YLE, Lam KSL, Xu A, Wong DSH, Cheung YY, Chan JTJ
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013


List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Hui Y.L.E., Managing Hypertension and Dyslipidaemia in diabetic patients, Update on Diabetes Management 2013. 2013.
Hui Y.L.E., Xu A., Yang H.B. and Lam K.S.L., Obesity as the common soil of non-alcoholic fatty liver disease and diabetes: Role of adipokines., J Diabetes Investig. . 2013, 4: 413-425.
Hui Y.L.E., Yeung M.C., Cheung P.T., Kwan E.Y.W., Tan K.C.B., Lam K.S.L. and Chan A.O.K., The clinical significance of aldosterone synthase deficiency: report of a novel mutation in the CYP11B2 gene., BMC Endocrine Disorder.. 2014, 14: 29.
Lam K.S.L., Hui Y.L.E., Yuen M.A.M., Yeung C.Y., Woo Y.C., Fong H.Y. and Xu A., Circulating fibroblast growth factor 21 level predicts the progression of diabetes nephropathy in patients with type 2 diabetes, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo, 17-24 Jun 2014, Chicago, USA.. 2014.
Loong C.H., Woo Y.C., Hui Y.L.E., Leung E.L., Yee S.W., Lam K.S.L. and Tan K.C.B., Advanced osteoporosis triage system shortens the waiting time for osteoporosis clinic., Health Authority Convention in Hong Kong.. 2014.
Loong C.H., Woo Y.C., Hui Y.L.E. and Tan K.C.B., Simple risk assessment tools to identify post-menopausal women with fracture risk in community., 15th Regional Osteoporosis Conference.. 2014.
Woo Y.C., Loong N.H.C., Hui Y.L.E., Leung E., Kung A.W.C. and Tan K.C.B., History- an physical examination-based model showed good discrimination ability in fracture prediction., World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Disease in Seville.. 2014.
Yeung C.Y., Hui Y.L.E., Lam T.H., Chow W.S., Woo Y.C., Fong H.Y., Xu A., Cheung B.M.Y. and Lam K.S.L., Plasma fibrinogen level as a predictor of incident metabolic syndrome in a community-based prospective study in Hong Kong Chinese, European Association for the Study of Diabetes. 2013.


Researcher : Hung I.F.N.

Project Title:Efficacy and safety of a novel intradermal live-attenuated varicella zoster vaccine in hematopoietic stem cell transplantation donors: a randomized double-blind placebo-controlled trial
Investigator(s):Hung IFN, Lie AKW, Leung AYH, To KKW, Yuen KY
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2013


List of Research Outputs



Researcher : Hung IFN

Project Title:Efficacy and safety of a novel intradermal live-attenuated varicella zoster vaccine in hematopoietic stem cell transplantation donors: a randomized double-blind placebo-controlled trial
Investigator(s):Hung IFN, Lie AKW, Leung AYH, To KKW, Yuen KY
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2013


List of Research Outputs

Chan F.H., Chan T.C.I., Hung I.F.N., Luk J.K.H., Chu L.W., Ng W.C., Law T.C. and Cheng V.C.C., Early Identification of an Influenza Outbreak in a Nursing Home with High Vaccination Coverage Facilitates Implementation of Infection-Control Measures and Prevents Spreading of Influenza Infection, Journal of American Medical Directors Association. 2014, 15(4): 300-1.
Chan S.S.C., Leung D.Y., Leung A.Y.M., Lam C.L.K., Hung I.F.N., Chu D., Chan C.K., Johnston J.M., Liu S.H., Liang R.H.S., Lam T.H. and Yuen K.Y., A nurse-delivered brief health education intervention to improve pneumococcal vaccination rate among older patients with chronic diseases: A cluster randomized controlled trial., International journal of nursing studies. 2014.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Efficacy of trivalent seasonal influenza vaccination in reducing mortality and hospitalization in Chinese nursing home older adults, Journal of the American Medical Directors Association . 2013, 14: 889-894.
Chan T.C.I., Luk J.K.H., Chan F.H.W., Chu L.W. and Hung I.F.N., Factors Associated with Seasonal Influenza Vaccination in Chinese Nursing Home Older Adults , Journal of the American Medical Directors Association . 2013, 14(10): 772-774.
Chan T.C.I., Hung I.F.N., Chan K.H., Li P.Y., Li T.W., Luk J.K.H., Chu L.W. and Chan F.H.W., Immunogenicity and Safety of Intradermal Trivalent Influenza Vaccination in Nursing Home Older Adults: A Randomized Controlled Trial., Journal of American Medical Directors Association. 2014.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Inadequate Knowledge of Pneumococcal Vaccine of Nursing Home Healthcare Workers Affects the Pneumococcal Vaccination Uptake of Older Adults in Nursing Homes , Journal of the American Geriatrics Society . 2013, 61(8): 1429-1430.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Predictor of Recurrent Hospitalization in Older Adults?, Journal of the American Medical Directors Association . 2013, 14(9): 706-707.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Risk Factor of Mortality in Chinese Older Adults?, Journal of the American Geriatrics Society . 2013, 61(8): 1430-1432.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Prevalence of Influenza Vaccination and Associated Factors in Chinese Nursing Home Healthcare Workers, Journal of the American Geriatrics Society . 2013, 61(10): 1824-1827.
Cheng V.C.C., Tai J.W.M., Chen J.H.K., So S.Y., Ng W.C., Hung I.F.N., Leung S.S., Wong S.C.Y., Chan T.C., Chan F.H., Ho P.L. and Yuen K.Y., Proactive infection control measures to prevent nosocomial transmission of vancomycin-resistant enterococci in Hong Kong.ournal of the Formosan Medical Association, Journal of the Formosan Medical Association. 2014.
Hung I.F.N., China Experience on H7N9 Infection , Continuing Threat of Influenza: Epidemiology, Transmission, Management, and Control Policy, Taiwan, 16 Nov 2013. 2013.
Hung I.F.N., Complications and Prevention of Influenza and Pneumonia, Lecture for Baptist Hospital, Hong Kong, 22 Oct 2013. 2013.
Hung I.F.N., Current Trend of MRSA & Streptococcus Pneumoniae Infections in Hong Kong , The Hong Kong Society for Infectious Disease Evening Symposium 2013, Hong Kong, 12 Dec 2013. 2013.
Hung I.F.N., Li T.W., To K.K.W., Ho T.Y., Chan J.F.W., Chan K.H. and Yuen K.Y., Efficacy of Combined Influenza and 23-valent Polysaccharide Pneumococcal Vaccines in Chronic Smoker, Pathogenesis of Respiratory Viruses at Keystone Resort, Colorado, USA, 19-24 January 2014.
Hung I.F.N., Facts about Pneumococcal Disease, The 2nd Beijing-Hong Kong Specialists in Infectious Diseases Forum, Beijing, China, 14 Nov 2013. 2013.
Hung I.F.N., Intestinal Microbiota in Health & Disease , The Hong Kong Society of Gastroenterology 15th Joint Annual Scientific Meeting, Hong Kong, 31 Aug 2013. 2013.
Hung I.F.N., New Guidelines on the Prevention of Pneumococcal Disease in Adults - An Interactive Forum, Hong Kong Primary Care Conference 2014 and 4-Party General Practice / Family Conference 2014, "With The Patients, For The Patients - Achieving Health Equity in Primary Care", Hong Kong College of Physicians, Hong Kong, 7 Jun 2014 . 2014.
Hung I.F.N. and Yuen K.Y., Response, Chest. 2014, 145(2): 435.
Hung I.F.N., Update on Helicobacter pylori Infection , The 4th Cross-straits Digestive Forum and the World Chinese Digestive Summit, Xiamen, China, 21-24 Nov 2013. 2013.
Hung I.F.N., Updates on Influenza Vaccination , The 4th Annual World Congress of Virus and Infection (WCVI-2013), Wuhan, China, 31 Jul 2013. 2013.
Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.
Lam Y.F., Wong D.K.H., Seto W.K.W., To K.K.W., Hung I.F.N., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., HLA-DP and interferon gamma receptor-2 gene variants and their association with viral hepatitis activity in chronic hepatitis B infection., Journal of Gastroenterology and Hepatology. 2014, 29(3): 533-539.
Leung W.K., Lo O.S.H., Liu K.S., Tong S.M., But Y.K.D., Lam F.Y., Hsu A.S.J., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., Detection of Colorectal Adenoma by Narrow Band Imaging (HQ190) vs. High-Definition White Light Colonoscopy: A Randomized Controlled Trial, Am J Gastroenterol. 2014, 109(6): 855-63.
Leung W.K., Liu K.S.H., Seto W.K.W., Chan K.H., Tong S.M., Yuen R.M.F. and Hung I.F.N., Factors for hepatitis B vaccination and abnormal liver function in Chinese patients with inflammatory bowel disease: a single center experience, J Dig Dis. 2013, 14: 596-603.
Liu K.S., Hung I.F.N., Seto W.K.W., Tong S.M., Hsu A.S.J., Lam F.Y., But Y.K.D., Wong S.Y. and Leung W.K., Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial, Gut. 2013.
Liu K.S.H., Hung I.F.N., Seto W.K.W., But Y.K.D., Hsu A.S.J., Tong S.M., Chan K.H., Tan V.P.Y. and Leung W.K., Immune Responses to intramuscular or intradermal trivalent influenza vaccines in patients with inflammatory bowel disease: A randomized controlled trial, Asian Organization for Crohn's and Colitis. 2014.
Lo O.S.H., Liu K.S.H., Tong S.M., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., New High Definition Narrow Band Imaging vs Conventional White Light Colonoscopy for Detection of Colorectal Adenomas in Symptomatic Patients: A Randomized Controlled Trial with Tandem Colonoscopy, United European Gastroenterology Week, 12-16 Oct 2013, Berlin, Germany. 2013.
Seto W.K.W., Lam Y.F., Fung J.Y.Y., Wong D.K.H., Huang F.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after five years of entecavir treatment, J Gastroenterol Hepatol. 2013, 29(5): 1028-34.
To K.K.W., Zhou J., Song Y., Hung I.F.N., Ip W.C.T., Cheng Z., Chan S.F., Kao R.Y.T., Wu A.K.L., Chau S.S., Luk W.K., Ip M.S.M., Chan K.H. and Yuen K.Y., Surfactant protein B gene polymorphism is associated with severe influenza., Chest. 2014, 145(6): 1237-1243.
Wong D.K.H., Kopaniszen M., Omagari K., Tanaka Y., Fong D.Y.T., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Zhang A.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Effect of Hepatitis B Virus Reverse Transcriptase Variations on Entecavir Treatment Response, Journal of Infectious Diseases. 2014.
Wu J.T.K., Leung S.M., Perera R.A.P.M., Chu K.W., Lee C.K., Hung I.F.N., Lin C.K., Lo S.V., Lau Y.L., Leung G.M., Cowling B.J. and Peiris J.S.M., Inferring influenza infection attack rate from seroprevalence data (abstract & poster presentation), Hong Kong College of Community Medicine Annual Scientific Meeting, 28 September 2013, Hong Kong. Hong Kong, HKCCM, 2013.
Zhang J., Li C., To K.K.W., Zhu H., Lee C.Y., Li C., Chan J.F.W., Hung I.F.N. and Yuen K.Y., Toll-like receptor 7 agonist imiquimod in combination with influenza vaccine expedites and augments humoral immune responses against influenza A(H1N1)pdm09 virus infection in BALB/c mice., Clinical and vaccine immunology. 2014, 21(4): 570-579.
Zheng M.H., Seto W.K.W., Shi K.Q., Wong D.K.H., Fung J.Y.Y., Hung I.F.N., Fong D.Y.T., Yuen J.C.H., Tong T., Lai C.L. and Yuen R.M.F., Artificial neural network accurately predicts hepatitis B surface antigen seroclearance, PLoS One. 2014, 9(6): e99422.


Researcher : Hwang YYG

List of Research Outputs

Chan C.Y.J., Hwang Y.Y.G. and Luk J.K.H., Mycosis fungoides in elderly adults--a diagnostic challenge., Journal of the American Geriatrics Society . Wiley Online Library, 2014, 62(4): 786-7.
Chan S.Y., Gill H., Hwang Y.Y.G., Sim J., Tse C.T.A., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Annals of Hematology. 2014, 93(3): 493-498.
Kwong Y.L., Singh G.H.H., Leung A.Y.H., Tse E.W.C., Lie A.K.W., Hwang Y.Y.G., Chan T.S.Y. and Chim J.C.S., Faculty Knowledge Exchange (KE) Award 2013: 'Multi-media Haematology Protocol: Haematology Protocol Book, iPad/iPhone App, Internet Website' (Group Award) , The University of Hong Kong. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing hematopoietic stem cell transplant: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing rituximab-containing chemotherapy: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Singh G.H.H., Hwang Y.Y.G., Chan S.Y.T., Pang A.W.K., Leung A.Y.H., Tse E.W.C. and Kwong Y.L., Valganciclovir suppressed Epstein Barr virus reactivation during immunosuppression with alemtuzumab, Journal of Clinical Virology. 2014, 59: 255-258.


Researcher : Ip MSM

Project Title:The efficacy of the modified oral appliance in the treatment of mild and moderate obstructive Sleep Apnoea
Investigator(s):Ip MSM
Department:Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:02/1997


Project Title:The effect of oral appliance (OA) in treatment of obstructive sleep apnoea
Investigator(s):Ip MSM, Peh WCG, Cooke MS
Department:Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:06/1997


Project Title:Role of adiponectin in obstructive sleep apnoea
Investigator(s):Ip MSM, Lam KSL
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:Candidate genes of obstructive sleep apnoea syndrome in Hong Kong Chinese
Investigator(s):Ip MSM, Lam KSL, Song Y, Sham PC
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2005


List of Research Outputs

HAN Q., Yeung S.C., Ip M.S.M. and Mak J.C.W., Cellular mechanisms in intermittent hypoxia-induced cardiac damage in vivo, J Physiol Biochem. Springer, 2014, 70: 201-213.
HAN Q., Yeung S.C., Ip M.S.M. and Mak J.C.W., Intermittent hypoxia-induced NF-kB and HO-1 regulation in human endothelial EA.hy926 cells, Cell Biochem. Biophys.. 2013, 66: 431-441.
Ho J.C.M., Au W.Y., HAN L., Kwong Y.L. and Ip M.S.M., Effect of therapeutic arsenic exposure on pulmonary function, Respiratory medicine. 2013, 107(9): 1423-1430.
Ip M.S.M., Asian Pacific Society of Respirology Medal, Asian Pacific Society of Respirology . 2013.
Ip M.S.M., Co-chairman, Cocktail Symposium - New Targeted Therapy in Lung Cancer , 19th Hong Kong Medical Forum, Hong Kong, May 2014. 2014.
Ip M.S.M., Co-chairman, Modern view of the common sleep-disordered breathing, The 2nd ASEAN Sleep Congress, Bangkok, Thailand. 2013.
Ip M.S.M., Co-chairman, Oral Session : OS21; Others 1, 18th Asian Pacific Society of Respirology, Yokohama, Japan, Nov 2013. 2013.
Ip M.S.M., Co-chairman, Poster Session : 2-D2; COPD 7, 18th Asian Pacific Society of Respirology, Yokohama, Japan, Nov 2013. 2013.
Ip M.S.M., Co-chairman, Poster Session : 2-E3; Respiratory Neurology and Sleep 2, 18th Asian Pacific Society of Respirology, Yokohama, Japan, Nov 2013. 2013.
Ip M.S.M., Co-chairman, Symposium on Sleep Apnoea & Respiratory Failure, Autumn Respiratory Seminar, HKTS/ACCP (HK & Macau Chapter), Hong Kong, Nov 2013. 2013.
Ip M.S.M., Glucose metabolism dysregulation in OSA, Chest World Congress, Madrid, Spain, Mar 2014. 2014.
Ip M.S.M., Improving CPAP compliance in OSA, The 2nd ASEAN Sleep Congress, Bangkok, Thailand. 2013.
Ip M.S.M., Member of Advisory Board, Sleep and Biological Rhythms. 2013.
Ip M.S.M., Member of Editorial Board, Journal of Thoracic Disease. 2013.
Ip M.S.M., Member of Editorial Board, Sleep Medicine. 2013.
Ip M.S.M., OSA and cardiometabolic disorders - so near yet so far, Joint Congress of Asia Sleep Society of Medicine (ASSM) & 8th National Congress of the Chinese Sleep Research Society (CSRS), Beijing, China, Jun 2014. 2014.
Ip M.S.M., Treatment of OSA - What really matters?, 3rd International Conference on Respiratory Diseases, Guangzhou, China, Oct . 2013.
Ip M.S.M., Treatment of sleep apnea - Practical advances, Sleep Symposium, HKU, Sep 2013. 2013.
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Lai A.Y.K., Fong D.Y.T., Lam C.M.J., Weaver T. and Ip M.S.M., Linguistic and psychometric validation of the Chinese version of the self-efficacy measures for sleep apnea, Sleep Medicine. 2013, 14(11): 1192-1198.
Lai Y.K.A., Lam C.M.J., Fong D.Y.T. and Ip M.S.M., Long-term efficacy of motivational interviewing on improving continuous positive airway pressure adherence in obstructive sleep apnea: A randomized controlled trial, European Respiratory Society Annual Congress, Barcelona, Spain, Sep 2013. Programme Book: p. 374 (P3595).
Lai Y.K.A., Lam C.M.J., Cheong M.Y.Y. and Ip M.S.M., The dose-response relationship between CPAP adherence and the daily performance in subjects with OSA, 18th Congress of the Asian Pacific Society of Respirologym Yokohama, Japan, Nov 2013. Respirology. 2013, 18(4): PS379.
Lam C.L.D., Chan L.K. and Ip M.S.M., Enhancement of teaching and learning with Clinical Respiratory Medicine Image MOODLE: bridging the knowledge gaps in clinical teaching, Frontiers in Medical and Health Sciences Education, December 6-7 2013, Hong Kong. 2013.
Lam C.M.J. and Ip M.S.M., OSA: Metabolic consequences: Pathophysiology and Clinical Implications, In: Patrick Levy, Electronic Book on Sleep Disordered Breathing. 2014.
Lee Y.K.M., Mak J.C.W. and Ip M.S.M., Intermittent hypoxia-induced endothelial activation in EA.hy926 cells in vitro, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal . 2014, 20 (Supp 1): P.31 (46).
Liang Y., Ip M.S.M. and Mak J.C.W., Differential effects of epigallocatechin gallate on cigarette smoke-induced upregulation of CINC-1 and IL-6 in Rat H9c2 cardiomyocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Suppl 1): P 33 (50).
Lui M.M., Tse H.F., Mak J.C.W., Lam C.M.J., Lam C.L.D., Tan K.C.B. and Ip M.S.M., Altered profile of circulating endothelial progenitor cells in obstructive sleep apnea, Sleep and Breathing. Springer, 2013, 17: 937-942.
Mak J.C.W., Lau K.W. and Ip M.S.M., Effects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cells , 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Suppl 1): P 34 (52).
Mak J.C.W., Ho S.P., Ho A.S., Law B.K., Cheung A.H.K., Ho J.C.M., Ip M.S.M. and Chan M.M.W., Sustained elevation of systemic oxidative stress and inflammation in exacerbation and remission of asthma, ISRN Allergy. 2013, 561831.
Tam T.C., Ho J.C.M., Wong M.K., Wong W.M., Wang J.K., Lam J.C., Lui M.M., Lam W.K., Ip M.S.M. and Lam C.L.D., Treatment Outcomes in Elderly with Advanced-stage Non-small Cell Lung Cancer, LUNG. Springer, 2013, 191: 645 - 654.
To K.K.W., Zhou J., Song Y., Hung I.F.N., Ip W.C.T., Cheng Z., Chan S.F., Kao R.Y.T., Wu A.K.L., Chau S.S., Luk W.K., Ip M.S.M., Chan K.H. and Yuen K.Y., Surfactant protein B gene polymorphism is associated with severe influenza., Chest. 2014, 145(6): 1237-1243.
WU L.K., Chan C.H., Ip M.S.M. and Shum D.K.Y., The Role of Heparanase in Controlling Airway Syndecan-1 Shedding and Airway Inflammation , 2013.
WU L.K., Chan C.H., Mak J.C.W., Tan C., Lam C.L.D., Ip M.S.M. and Shum D.K.Y., Using Polyanionic Heparin Mimetics for the treatment of COPD, 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, June 14, 2014.
Wang Y., Yeung S.C., Ip M.S.M. and Mak J.C.W., Suppression of inflammation during adipogenic differentiation in human preadipocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Supp 1): P 42 (68).


Researcher : Jim MH

List of Research Outputs

Chan P.H.M., Liu S., Tse H.F., Chow W.H., Jim M.H., Ho H.H. and Siu D.C.W., Long-term clinical outcomes of drug-eluting stents vs. bare-metal stents in Chinese geriatric patients, Journal of Geriatric Cardiology. 2013.


Researcher : Jin Y

Project Title:Cytogenetic and molecular genetic characterization of esophageal carcinomas
Investigator(s):Jin Y, Kwong YL, Tsao GSW
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:10/2002




Researcher : Kam KM

List of Research Outputs

Kam K.M., Cheung M.C.H., Zhu J.J., Cheng W.W., Sat E.W.Y., Tam P.K.H. and Lui V.C.H., Perturbation of Hoxb5 signaling in vagal and trunk neural crest cells causes apoptosis and neurocristopathies in mice, Cell Death & Differentiation. 2013, 21(2): 278-289.


Researcher : Keung WWY

Project Title:Promoting maturation of hESC-derived cardiomyocytes: the interplay between mitochondria, calcium and reactive oxygen species
Investigator(s):Keung WWY, Li RA
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:01/2013
Completion Date:06/2014




Researcher : Kong MCW

Project Title:Characterization of early-staged human embryonic stem cells cardiomyocytes (hESC-CMs): A potential cell source for successful cardiomyoplasty
Investigator(s):Kong MCW, Li RA
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012
Completion Date:04/2014


Project Title:Generation of homogeneous ventricular cardiomyocytes (VCMs) from human pluripotent stem cells (hPSC)
Investigator(s):Kong MCW
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:12/2012
Completion Date:05/2014




Researcher : Kopaniszen M

List of Research Outputs

Fung J.Y.Y., Lai C.L., Wong D.K.H., Seto W.K.W., Kopaniszen M. and Yuen R.M.F., Level of hepatitis B surface antigen and not HBV DNA level after HBeAg seroclearance is predictive of HBsAg seroclearance, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S259.
Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.


Researcher : Kumana CR

List of Research Outputs

Kumana C.R., Cheung B.M.Y. and Tse H.F., Relative versus absolute drug-therapy benefits and safety: Lessons from ARISTOTLE, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 25.


Researcher : Kung AWC

Project Title:Cost-effective osteoporosis intervention thresholds for Hong Kong Southern Chinese postmenopausal women
Investigator(s):Kung AWC, McGhee S
Department:Medicine
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:10/2009


List of Research Outputs

Cheung C.L., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Genetic variant in vitamin D binding protein is associated with serum 25-hydroxyvitamin D and vitamin D insufficiency in southern Chinese., J Hum Genet. 51, 2013, 58: 749.
Cheung C.L., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Genetic variants in GREM2 are associated with bone mineral density in a southern Chinese population, Journal of Clinical Endocrinolog and Metabolism. 2013, 98: E1557-61.
Cheung C.L., Lau K.S., Sham P.C. and Kung A.W.C., Research Output Prize, Faculty of Medicine, the University of Hong Kong. 2013.
Cheung E., Kung A.W.C. and Tan K.C.B., Outcomes of applying the NOF, NOGG and Taiwanese guidelines to a cohort of Chinese early postmenopausal women., Clinical endocrinology (Oxford). 2014, 80: 200-7.
Woo Y.C., Loong N.H.C., Hui Y.L.E., Leung E., Kung A.W.C. and Tan K.C.B., History- an physical examination-based model showed good discrimination ability in fracture prediction., World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Disease in Seville.. 2014.
Xiao S.M., Kung A.W.C., Sham P.C. and Tan K.C.B., Genetic analysis of recently identified osteoporosis susceptibility genes in southern Chinese., Journal of Clinical Endocrinology and Metabolism. 2013, 98: 1827-34.


Researcher : Kung MHW

List of Research Outputs

Ho W.L., Tse H.M., Liu H., Lu S., Ho W.M., Kung M.H.W., Ramsden D.B. and Ho S.L., Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System, PLoS ONE. 2013, 8(9): e74065.
Liu H., Lu S., Ho W.L., Tse H.M., Pang S.Y.Y., Kung M.H.W., Ho W.M., Ramsden D.B., Zhou Z. and Ho S.L., LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. , Annals of Clinical and Translational Neurology. 2014, 1(3): 199-208.
Liu H., Ho W.L., Tse H.M., Leung C.T.G., Kung M.H.W., Zhou Z., Ramsden D.B. and Ho S.L., Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity , 18th International Congress of Parkinson’s Disease and Movement Disorders, June 2014, sweden.. 2014, 29.


Researcher : Kwan SC

List of Research Outputs

Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.
Guo Y., Chung S.K., Siu D.C.W., Kwan S.C., Ho W.L., Yeung P.K.K., Teo K.C. and Chan K.H., Endothelin-1 overexpression exacerbate experimental allergic encephalomyelitis, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong. 2014.


Researcher : Kwan SKJ

List of Research Outputs

Kwan S.K.J., Sykes L. and Wood E., Antiepileptic drugs for the prevention of post-stroke seizures: results of a Cochrane Systematic Review, Asia Pacific Geriatric Conference. 2014, 9;2: 56.
Kwan S.K.J., Nordin N., Poynter L. and Vassallo M., Body Mass Index and nutritional status are predictors of functional improvement from rehabilitation in older patients, Annual General Meeting of Hong Kong Geriatrics Society. 2014.
Kwan S.K.J., Editorial Board Member, Journal of Heart Surgery and Treatment . ScienceScript LLC, 2014.
Kwan S.K.J., Kwan J. and Vassallo M., How does cognitive impairment impact on functional improvement following the rehabilitation of elderly patients?, International Journal of Clinical Practice. 2013, 67: 811-815.
Kwan S.K.J., Horsfield G., Bryant T., Gawne-Cain M., Durward G., Byrne C.D. and Englyst N.A., IL-6 is a predictive biomarker for stroke associated infection and future mortality in the elderly after an ischemic stroke, Experimental Gerontology. 2013, 48: 960-965.
Kwan S.K.J., Post-stroke infection, Postgraduate Meeting on Stroke Medicine, Princess Margaret Hospital. 2014.
Kwan S.K.J., Study on the interaction between vascular risk factors, MRI, cognition and outcome ($300,000), Start-Up Grant, Department of Medicine, HKU. 2014.
Kwan S.K.J., The art of medicine: the humanistic care of a person with stroke, Guest Seminar, Medical Ethics and Humanities Unit, The University of Hong Kong. 2014.
Kwan S.K.J. and Englyst N., Weight loss after a stroke and inflammation, Asia Pacific Geriatric Conference. 2014, 9;2: 52.
Sykes L., Wood E. and Kwan S.K.J., Antiepileptic drugs for the primary and secondary prevention of seizures after stroke, In: The Cochrane Collaboration, Cochrane Database of Systematic Reviews: Reviews. Chichester, UK, John Wiley & Sons, Ltd, 2014.


Researcher : Kwan SM

List of Research Outputs

Chu L.W., So J.C., Wong L.C., Luk J.K.H., Chiu P.K.C., Chan S.Y., Kwan S.M., Chau J., Hui E., Woo J. and McGhee S., Community end-of-life care among Chinese older adults living in nursing homes, Geriatrics & Gerontology International. 2014, 14(2): 273-84.


Researcher : Kwong YL

Project Title:Provision of purine analogues for the treatment of patients with chronic lymphoid malignancies
Investigator(s):Kwong YL, Liang RHS
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/1997


Project Title:Molecular mechanisms and consequences of downregulation of p73 in natural killer cell lymphoma
Investigator(s):Kwong YL
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:Molecular basis of arsenic resistance in tumours
Investigator(s):Kwong YL, Tse EWC
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Provision of free cytogenetic and molecular testing for monitoring of disease relapse after bone marrow transplantation
Investigator(s):Kwong YL, Liang RHS, Lie AKW, Au WY
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:11/2004


Project Title:Provision of ibritumomab for the treatment of lymphoma
Investigator(s):Kwong YL, Liu KY
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2008


Project Title:Provision of oral arsenic trioxide free to patients with cancers
Investigator(s):Kwong YL, Au WY, Chim JCS
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2008


Project Title:Provision of ibritumomab for the treatment of Iymphoma
Investigator(s):Kwong YL, Liu KY
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:05/2010


Project Title:Provision of clofarabine for the treatment of relapsed or refractory acute leukaemia
Investigator(s):Kwong YL, Leung AYH, Tse EWC
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Provision of bendamustine for the treatment of non-Hodgkin lymphoma and chronic lymphocytic leukemia
Investigator(s):Kwong YL, Leung AYH, Tse EWC
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2012


Project Title:Provision of free azacitidine for high-risk patient with myelodysplastic syndrome (MDS)
Investigator(s):Kwong YL, Leung AYH
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2014


List of Research Outputs

Chan S.Y., Gill H., Hwang Y.Y.G., Sim J., Tse C.T.A., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Annals of Hematology. 2014, 93(3): 493-498.
Chan S.Y.T., Kwong Y.L. and Tse E.W.C., Novel therapeutic agents for T-cell lymphomas, Discovery Medicine. 2013, 16(86): 27-35.
Chan T.S., Gill H., Hwang Y.Y., Sim P.Y.J., Tse A.C., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Ann Hematol. 2013, Epub ahead of print.
Cheng C.W., Kwong Y.L. and Tse E.W.C., Best Abstract in Basic Science & Translational (Poster), 19th Medical Research Conference Department of Medicine, HKU. 2014.
Cheung C.Y., Wong Y.H.I., Yan K.W. and Kwong Y.L., Cytomegalovirus oral lesions: harbinger of retinitis in the absence of viraemia, Ann Hematol. 2014.
Cheung Y.M., Leung A.Y.H., Chan S.C., Trendell-Smith N.J., So C.C. and Kwong Y.L., Fatal graft-versus-host disease after unrelated cadaveric liver transplantation due to donor/recipient human leucocyte antigen matching (Letter to the Editor), Internal Medicine Journal. 2014, 44(4): 425-426.
Chim J.C.S., Liu H., Lie A.K.W., Chan Y.T.E., Ho S., Wong M. and Kwong Y.L., Unsustained CR of less than 24 months after autologous stem cell transplantation predicts aggressive myeloma with short survival, Hematol Oncol. 2014, Epub ahead of print.
Gill H., Au W.Y. and Kwong Y.L., Oral Arsenic Trioxide - Based Maintenance Without Hematopoietic Stem Cell Transplantation At Second Remission In Acute Promyelocytic Leukemia - A Prospective Follow-Up Study Of 65 Patients, 55th ASH Annual Meeting and Exposition, New Orleans. Blood, Blood, 2013, 122 (21).
Gill H., Au W.Y., Cheung W.W. and Kwong Y.L., Oral Arsenic Trioxide Based Regimen As Salvage Treatment For Relapsed Or Refractory Mantle Cell Lymphoma, 55th ASH Annual Meeting and Exposition, New Orleans. Blood, Blood, 2013, 122 (21).
Ho J.C.M., Au W.Y., HAN L., Kwong Y.L. and Ip M.S.M., Effect of therapeutic arsenic exposure on pulmonary function, Respiratory medicine. 2013, 107(9): 1423-1430.
Khong P.L., Huang B., Lee E.Y.P., Chan K.S. and Kwong Y.L., Midtreatment 18F-FDG PET/CT scan for early response assessment of SMILE therapy in natural killer/T-ccll lymphoma: a prospective study from a single center, Journal of Nuclear Medicine . 2014, 55(6): 911-916.
Kwok G., Kan A., Leung R.Y., Tam S., Lau W.C.S. and Kwong Y.L., Pyrexia, massive hepatomegaly, and extreme hyperferritinemia, Am J Med. 2014, 127(6): e13-4.
Kwong Y.L., Singh G.H.H., Leung A.Y.H., Tse E.W.C., Lie A.K.W., Hwang Y.Y.G., Chan T.S.Y. and Chim J.C.S., Faculty Knowledge Exchange (KE) Award 2013: 'Multi-media Haematology Protocol: Haematology Protocol Book, iPad/iPhone App, Internet Website' (Group Award) , The University of Hong Kong. 2013.
Kwong Y.L., Pang A.W.K., Leung A.Y.H., Chim J.C.S. and Tse E.W.C., Quantification of circulating Epstein-Barr virus DNA in NK/T-cell lymphoma treated with the SMILE protocol: diagnostic and prognostic significance, Leukemia. Epub ahead of print, 2013, Epub.
Lam S.K., Mak J.C.W., ZHENG C., LI Y., Kwong Y.L. and Ho J.C.M., Downregulation of thymidylate synthase with arsenic trioxide in lung adenocarcinoma, International Journal of Oncology. 2014, 44: 2093-2102.
MAN C.H., LAM S.Y., Sun M.K.H., Chow H.C.H., Singh G.H.H., Kwong Y.L. and Leung A.Y.H., A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML, Blood. 2014, 123: 2530-2539.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing hematopoietic stem cell transplant: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing rituximab-containing chemotherapy: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Singh G.H.H., Hwang Y.Y.G., Chan S.Y.T., Pang A.W.K., Leung A.Y.H., Tse E.W.C. and Kwong Y.L., Valganciclovir suppressed Epstein Barr virus reactivation during immunosuppression with alemtuzumab, Journal of Clinical Virology. 2014, 59: 255-258.
Tse E.W.C., Leung R.Y.Y. and Kwong Y.L., Invasive fungal infections after obinutuzumab monotherapy for refractory chronic lymphocytic leukemia, Annals of Hematology. 2014.
Tse E.W.C. and Kwong Y.L., Management of Advanced NK/T-Cell Lymphoma, Current Hematologic Malignancy Reports. 2014.
WANG L., Kwong Y.L., Wong K.F., Kho C.S.B., Jin D., Tse E.W.C., Rosen A. and Chim J.C.S., Epigenetic inactivation of miR-34b/c in addition to miR-34a and DAPK1 in chronic lymphocytic leukemia, J Transl Med. 2014, 12(1): 52.
Wang L.Q., Kwong Y.L., Wong K.F., Kho C.S.B., Jin D., Tse E.W.C., Rosen A. and Chim J.C.S., Epigenetic inactivation of miR-34b/c in addition to miR-34a and DAPK1 in chronic lymphocytic leukemia, Journal of Translational Medicine. 2014, 12: 52-61.
Wang L.Q., Kwong Y.L., Kho C.S., Wong K.F., Wong K.Y., Ferracin M., Calin G.A. and Chim J.C.S., Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic leukemia - implications on constitutive activation of NFkappaB pathway, Mol Cancer.. 2013, 12: 173.


Researcher : LAM SY

List of Research Outputs

MAN C.H., LAM S.Y., Sun M.K.H., Chow H.C.H., Singh G.H.H., Kwong Y.L. and Leung A.Y.H., A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML, Blood. 2014, 123: 2530-2539.


Researcher : LEE PC

List of Research Outputs

Hoo R.L.C., LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and translational (Oral Presentation), 19th Medical Research Conference. 2014.
LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and Translational (Oral Presentation), 19th Medical Research Conference. 2014.


Researcher : LEE THJ

List of Research Outputs

KONG K.Y., Tang V.H.M., Pan K., HUANG Z., LEE T.H.J., Hinnebusch A., Jin D. and Wong C.M., Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing, Nucleic Acids Research. Oxford Journals, 2014, 42: 643-660.


Researcher : LI A

List of Research Outputs

Yau S.Y., LI A., Zhang E., Christie B.R., Xu A., Lee T.M.C. and So K.F., Sustained Running in Rats Adminstered Corticosterone Prevents the Development of Depressive Behaviors and Enhances Hoppocampal Neurogenesis and Synaptic Plasticity Without Increasing Neurotrophic Factor Levels. Cell Transplantation, 2014, 23: 481-492.


Researcher : LI C

List of Research Outputs

Peng H., Cai X.Q., Tsang T.K., Shen H.S., Wu X.H., Zhou Y.B., LI C. and Cheung B.M.Y., Do unsaturated fatty acids have beneficial effect on reduction of stroke risk in hypertensive population?, 17th Annual Scientific Meeting Institute of Cardiovasclar Science and Medicine 23 November 2013, Hong Kong. 2013, 21: 72.


Researcher : LI R

List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Lim A.I., Chan Y.Y., Tang S.C.W., Yiu W.H., LI R., Lai K.N. and Leung J.C.K., BMP-7 represses albumin-induced chemokine synthesis in kidney tubular epithelial cells through destabilization of NF-κB-inducing kinase., Immunol Cell Biol.. 2014, 92(5): 427-35.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.


Researcher : LI X

List of Research Outputs

Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.


Researcher : LI Y

List of Research Outputs

LI Y., Lam S.K., ZHENG C. and Ho J.C.M., The Role of Autophagy Induced by Tyrosine Kinase Inhibitors in Non-small Cell Lung Carcinoma, 15th World Conference on Lung Cancer. 2013.
LI Y., Lam S.K., ZHENG C. and Ho J.C.M., The Role of Autophagy Induced by Tyrosine Kinase Inhibitors in Non-small Cell Lung Carcinoma, 20th Hong Kong International Cancer Congress. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo , 15th World Conference on Lung Cancer. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo , 20th Hong Kong International Cancer Congress. 2013.
Lam S.K., Mak J.C.W., ZHENG C., LI Y., Kwong Y.L. and Ho J.C.M., Downregulation of thymidylate synthase with arsenic trioxide in lung adenocarcinoma, International Journal of Oncology. 2014, 44: 2093-2102.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Dual Action of Arsenic Trioxide on Thymidylate Synthase and Apoptosis in Mesothelioma , Conference on joining hands to eliminate asbestos hazards. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Dual action of arsenic trioxide on thymidylate synthase and apoptosis in mesothelioma, Conference on joining hands to eliminate asbestos hazards, Pneumoconiosis Compensation Fund Board, Hong Kong. 2013.
ZHENG C., Lam S.K., LI Y., Fong B.M., Mak J.C.W. and Ho J.C.M., Combination of arsenic trioxide and chemotherapy in small cell lung cancer, Lung Cancer. 2013, 82(2): 222-230.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, 15th World Conference on Lung Cancer. 2013.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, 20th Hong Kong International Cancer Congress. 2013.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, Journal of Thoracic Oncology. 2013, 8: S1041.


Researcher : LIANG Y

List of Research Outputs

LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Liang Y., Ip M.S.M. and Mak J.C.W., Differential effects of epigallocatechin gallate on cigarette smoke-induced upregulation of CINC-1 and IL-6 in Rat H9c2 cardiomyocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Suppl 1): P 33 (50).


Researcher : LIN M

List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.


Researcher : LIN SC

List of Research Outputs

Wong D.K.H., LIN S.C., Huang F.Y., Tsoi Y.Y.O., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Association of methylated histones and DNA methylases with hepatitis B virus covalently closed circular DNA and their association with hepatitis B virus replication, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S214.


Researcher : Lai AYK

List of Research Outputs

Lai A.Y.K., Fong D.Y.T., Lam C.M.J., Weaver T. and Ip M.S.M., Linguistic and psychometric validation of the Chinese version of the self-efficacy measures for sleep apnea, Sleep Medicine. 2013, 14(11): 1192-1198.


Researcher : Lai CL

Project Title:A preliminary assessment of safety and antiviral activity of open-label entecavir plus lamivudine therapy in subjects with chronic hepatitis B who have viremia on monotherapy in other entecavir trials
Investigator(s):Lai CL, Yuen RMF
Department:Medicine
Source(s) of Funding:Bristol-Myers-Squibb (HK) - General Award
Start Date:01/2003


Project Title:Long-term assessment of treatment outcomes with entecavir and lamivudine for chronic hepatitis B infection in patients who have enrolled in phase iii entecavir trials
Investigator(s):Lai CL, Yuen RMF
Department:Medicine
Source(s) of Funding:Bristol-Myers-Squibb (HK) - General Award
Start Date:10/2003


Project Title:A randomized, double-blind trial of Telbivudine (LdT) versus Lamivudine in adults with decompensated chronic hepatitis B and evidence of cirrhosis
Investigator(s):Lai CL, Yuen RMF
Department:Medicine
Source(s) of Funding:Idenix Pharmaceuticals, Inc - General Award
Start Date:01/2004


List of Research Outputs

Chen D.S., Chen P.J., Lu S.N., Yang P.M., Sung J., Lai C.L., Fung J.Y.Y., Bae S.H., Lee J.S., Kim H.S., Ahn S.H., Yoon G.H., Tanaka J., Wakita T., Aizaki H., Yonezawa A., Lino Y., Abe Y., Ward J., Lou L., Gore C., Mohamed R., Locarnini S., Wallace J., Wait S. and Johnston J., Report from a Viral Hepatitis Policy Forum on implementing the WHO Framework for Global Action on viral hepatitis in North Asia, Journal of hepatology : the journal of the European Association for the Study of the Liver. 2013, 59(5): 1073-80.
Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Defining Normal Liver Stiffness Range in a Normal Healthy Chinese Population without Liver Disease, PLoS One. 2013, 8(12): e85067.
Fung J.Y.Y., Seto W.K.W., Lai C.L. and Yuen R.M.F., Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment, Journal of Gastroenterology and Hepatology. Blackwell Publishing, 2014, 29(3): 428-434.
Fung J.Y.Y., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Hepatitis B surface antigen levels after hepatitis B e-antigen seroclearance: a longitudinal follow-up study, Liver Int. 2014.
Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Lai C.L. and Yuen R.M.F., High Prevalence of Non-Alcoholic Fatty Liver Disease in the Chinese - Results from the Hong Kong Liver Health Census, Liver Int. 2014.
Fung J.Y.Y., Lai C.L., Wong D.K.H., Seto W.K.W., Kopaniszen M. and Yuen R.M.F., Level of hepatitis B surface antigen and not HBV DNA level after HBeAg seroclearance is predictive of HBsAg seroclearance, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S259.
Fung J.Y.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Spontaneous hepatitis B e-antigen seroconversion without subsequent antiviral therapy is associated with higher rates of hepatitis B surface antigen seroclearance, Annual Meeting, American Association for the Study of Liver Disease. 2013.
Fung J.Y.Y., Poon R.T.P., Yu W.C., Chan S.C., Chan A.C.Y., Chok K.S.H., Cheung T.T., Seto W.K.W., Lo C.M., Lai C.L. and Yuen R.M.F., Use of liver stiffness measurement for liver resection surgery: correlation with indocyanine green clearance testing and post-operative outcome, PLoS One. 2013, 8(8): e72306.
Gane E.J., Lai C.L., Xie Q., Liaw Y.F., Thongsawat S., Chan H.L.Y., Wang Y., Hwang S.G., Safadi R., Jung M., Uddin A., Janssens N. and Trylesinski A., Evaluation of estimated glomerular filtration rate during continuous 4-year treatment with telbivudine in patients with bridging fibrosis/cirrhosis, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S426.
Gane E.J., Deray G., Liaw Y.F., Lim S.G., Lai C.L., Rasenack J., Wang Y., Papatheodoridis G., Di Bisceglie A., Buti M., Samuel D., Uddin A., Bosset S. and Trylesinski A., Telbivudine improves renal function in patients with chronic hepatitis B, Gastroenterology. 2014, 146: 138-146.
Huang F.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Estrogen represses anti-apoptotic genes expression via MiR-23a: contribution to sex differences in the development of hepatocellular carcinoma, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 667). Hepatology International. 2014, 8(S1): S243.
Huang F.Y., Wong D.K.H., Seto W.K.W., Zhang A.Y., Lee C.K., Lin C.K., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Sequence Variations of Full-Length Hepatitis B Virus Genomes in Chinese Patients with HBsAg-Negative Hepatitis B Infection, PLoS One. 2014, 9(6): e99028.
Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.
Lai C.L., Advisor, AbbVie APASL JAPAC Advisory Board Meeting, Brisbane, Australia, March 11. 2014.
Lai C.L., Antiviral Treatment: Are We Achieving our Goal?, HKASLD Expert Standalone Meeting 'Chronic hepatitis B management: learning from around the Asia region', Hong Kong, July 20. 2013.
Lai C.L., Chairman, Keynote Lecture II and Co-Chairman, Clinical Research Presentation II, SKLLR Symposium 2013 with a theme “From Bench Research to Patient Care”, State Key Laboratory for Liver Research (SKLLR), The University of Hong Kong, Hong Kong, October 5. 2013.
Lai C.L., Co-Convenor, Expert Panel Meeting: Recommendations for the management of chronic hepatitis B infection, organized by Department of Medicine, The University of Hong Kong, Cyberport, Hong Kong, December 7-8. 2013.
Lai C.L., Co-chairman, 19th Hong Kong Medical Forum (19th HKMF), Session: 'Gastrointestinal and Liver Diseases', Department of Medicine, The University of Hong Kong, May 3-4. 2014.
Lai C.L., Co-chairman, Panel Discussion, Session 1: Update on HBV-related HCC, 3rd Asia Hepatology Perspectives Forum, Busan, Korea, November 29-30. 2013.
Lai C.L., Debate: Immune tolerant patients: To treat or not to treat?, Session 2: Current HBV Issues in Asia, 3rd Asia Hepatology Perspectives Forum, Busan, Korea, November 29-30. 2013.
Lai C.L., Duration/endpoints of treatment, Expert Panel Meeting: Recommendations for the management of chronic hepatitis B infection, organized by Department of Medicine, The University of Hong Kong, Cyberport, Hong Kong, December 7-8. 2013.
Lai C.L., Future therapy, Expert Panel Meeting: Recommendations for the management of chronic hepatitis B infection, organized by Department of Medicine, The University of Hong Kong, Cyberport, Hong Kong, December 7-8. 2013.
Lai C.L., HCV epidemiology and unmet needs across the APAC region, Gilead HCV symposium ' Transforming HCV care across the Asia-Pacific region' during the Asian Pacific Association for The Study of the Liver (APASL) 2014, Brisbane, Australia, March 12. 2014.
Lai C.L., Hepatitis A, B, C, D, E and more, Wah Yan College, Kowloon, with a theme 'Public Health', Hong Kong, November 13. 2013.
Lai C.L., Hepatitis C Virus: Pegylated interferon (pegIFN) a2a vs a2b, GASTRO 2013 APDW/WOCG, Shanghai, China, September 21 – 24. 2013.
Lai C.L., Long term efficacy and safety of nucleoside analogues, Special Symposium: Optimizing treatment outcomes in hepatitis, 3rd APASL (Asian Pacific Association for the Study of the Liver) HCC (Hepatocellular Carcinoma) Conference with the concept, HCC in 3D: Dimension, Detection, Decision, Cebu City, Philippines, November 21-23. 2013.
Lai C.L., Long-term management of CHB: the ultimate endpoints, 8th HBV-Focus (第八届聚焦乙肝論坛), Chinese Hospital Association, Beijing, China, May 17. 2014.
Lai C.L., Member of the Organizing Committee, State Key Lab for Liver Research (SKLLR) Symposium. 2013.
Lai C.L., Member, Review Committee, American Association for the Study of Liver Diseases (AASLD). 2014.
Lai C.L., Member, External Review Committee (ERC) of Hong Kong Sanatorium & Hospital, Hong Kong. 2013.
Lai C.L., Panel member , 5th Hong Kong Hepatitis C Expert Input Forum in Hong Kong on March 1, 2014th Hong Kong Hepatitis C Expert Input Forum in Hong Kong, March 1. 2014.
Lai C.L., Ahn S.H., Lee K.S., Um S.H., Cho M., Yoon S.K., Lee J.W., Park N.H., Kweon Y.O., Sohn J.H., Lee J., Kim J.A., Han K.H. and Yuen R.M.F., Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B, Gut. BMJ Publishing Group, 2013, 63(6): 996-1004.
Lai C.L. and Yuen R.M.F., Reply, Hepatology. John Wiley and Sons Ltd, 2013, 58(5): 1857.
Lai C.L., Reviewer, Hepatology Research. 2013.
Lai C.L., Role of Antivirals in HBV-related HCC, Symposium 1: Risk Factors and Prevention of HCC in Asia Pacific, 3rd APASL (Asian Pacific Association for the Study of the Liver) HCC (Hepatocellular Carcinoma) Conference with the concept, HCC in 3D: Dimension, Detection, Decision, Cebu City, Philippines, November 21-23. 2013.
Lai C.L., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBV DNA and covalently closed circular DNA in chronic hepatitis B patients (Poster presentation), 49th Annual Meeting of the European Association for The Study of the Liver (EASL), London, United Kingdom, April 9-13. 2014.
Lai C.L., The treatment of chronic hepatitis B: The past, the present and the future, 302 Beijing Hospital Meeting, Beijing, China, May 20. 2014.
Lai C.L., The treatment of chronic hepatritis B: The past, the present and the future, Symposium IV: Future in the Managemnt of Chronic Liver Diseases, 26th Annual Scientific Meeting of the Hong Kong Association for the Study of Liver Disease, Hong Kong, November 10. 2013.
Lai C.L., Transforming your mind, Medical Humanities Guest Speaker Series – Year One “Conversations and Connections”, Medical Ethics and Humanities Unit, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, February 18. 2014.
Lai C.L., Treatment of chronic hepatitis B, Seminar on Viral Hepatitis for Nurses and Allied Health Professionals 2014, Centre of Health Protection, Department of Health, Hong Kong, May 15. 2014.
Lai C.L., Turning points in CHC care: how fast are things changing?, The Liver Week 2014, the 20th Annual Meeting of the Korean Association for the Study of the Liver (KASL) & Postgraduate Course, Jeju Island, Korea, June 12-14. 2014.
Lai C.L., 乙型及其他肝炎, Public seminar organized by the Hong Kong Hep B Free Foundation, Hong Kong, June 27. 2014.
Lam Y.F., Wong D.K.H., Seto W.K.W., To K.K.W., Hung I.F.N., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., HLA-DP and interferon gamma receptor-2 gene variants and their association with viral hepatitis activity in chronic hepatitis B infection., Journal of Gastroenterology and Hepatology. 2014, 29(3): 533-539.
Lu T., Seto W.K.W., Zhu R.X., Lai C.L. and Yuen R.M.F., Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection, World J Gastroenterol. 2013, 19(47): 8887-8894.
Seto W.K.W., Lam Y.F., Fung J.Y.Y., Wong D.K.H., Huang F.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after five years of entecavir treatment, J Gastroenterol Hepatol. 2013, 29(5): 1028-34.
Seto W.K.W., Lam Y.F., Liu S.H.K., Mak L.Y., Ko K.L.M., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Continuous Entecavir for Treatment-Naïve Chinese Chronic Hepatitis B in the Real World Setting: The Six-Year Results, Digestive Diseases Week 2014. Gastroenterology. 2014, 146(5): Suppl 1: S963-4.
Seto W.K.W., Hui A.J., Wong V.W.S., Wong G.L.H., Liu K., Lai C.L., Yuen R.M.F. and Chan H.L.Y., HBsAg and HBV DNA levels guiding entecavir cessation in HBeAg-negative chronic hepatitis B, Poster Presentation at the Gastro 2013 APDW/WCOG Shanghai, Asian Pacific Digestive Week 2013 ∣ World Congress of Gastroenterology, 21-24 September 2013, Shanghai, China. Journal of Gastroenterology and Hepatology. 2013, 28(Suppl 3): 414.
Seto W.K.W., Lai C.L. and Yuen R.M.F., Hepatitis viruses and hepatocellular carcinoma (Chapter 23), In: Prof. Shosuke Kawanishi (Suzuka University of Medical Science, Japan) and Prof. Hiroshi Ohshima (University of Shizuoka, Japan). , Cancer and Inflammation Mechanisms: Chemical, Biological and Clinical Aspects. 2014.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing hematopoietic stem cell transplant: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing rituximab-containing chemotherapy: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Liu K.S.H., Lai C.L. and Yuen R.M.F., Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B, Clinical Microbiology and Infection. 2014.
Seto W.K.W., Tanaka Y., Shinkai N., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Performance of a highly sensitive hepatitis B surface antigen assay among chronic hepatitis B patients after hepatitis B surface antigen seroclearance, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014. (Absno. 208). Hepatology International. 2014, 8(S1): S69.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Lai C.L. and Yuen R.M.F., Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy, Hepatology. 2013, 58(3): 923-31.
Seto W.K.W., Tsang O.T., Liu K., Chan J.M., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection, Journal of Viral Hepatitis. 2013, 20(7): 470-7.
Seto W.K.W., Hui A.J., Wong V.W., Wong G.L., Liu K.S., Lai C.L., Yuen R.M.F. and Chan H.L., Treatment cessation of entecavir in Asian patients with hepatitis B e antigen negative chronic hepatitis B: a multicentre prospective study, Gut. 2014.
Wong D.K.H., Tsoi Y.Y.O., Huang F.Y., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Application of co-amplification at lower denaturation temperature-PCR (COLD-PCR) sequencing for the early detection of antiviral drug resistance mutations of hepatitis B virus, Journal of Clinical Microbiology. 2014.
Wong D.K.H., LIN S.C., Huang F.Y., Tsoi Y.Y.O., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Association of methylated histones and DNA methylases with hepatitis B virus covalently closed circular DNA and their association with hepatitis B virus replication, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S214.
Wong D.K.H., Kopaniszen M., Omagari K., Tanaka Y., Fong D.Y.T., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Zhang A.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Effect of Hepatitis B Virus Reverse Transcriptase Variations on Entecavir Treatment Response, Journal of Infectious Diseases. 2014.
Wong D.K.H., Fung J.Y.Y., Lee C.K., Seto W.K.W., Leung J., Huang D.K.H., Lin C.K., Lai C.L. and Yuen R.M.F., Hepatitis B virus serological and virological activities in blood donors with occult hepatitis B, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 868). Hepatology International. 2014, 8(S1): S149.
Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.
ZHANG A., Wong D.K.H., Huang F.Y., Fung J.Y.Y., Seto W.K.W., Poon R.T.P., Lai C.L. and Yuen R.M.F., Characterization of intrahepatic HBV quasispecies genetic variability within the pre-S region in patients with HBV-related hepatocellular carcinoma, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Zheng M.H., Seto W.K.W., Shi K.Q., Wong D.K.H., Fung J.Y.Y., Hung I.F.N., Fong D.Y.T., Yuen J.C.H., Tong T., Lai C.L. and Yuen R.M.F., Artificial neural network accurately predicts hepatitis B surface antigen seroclearance, PLoS One. 2014, 9(6): e99422.


Researcher : Lai KN

Project Title:The role of the renin-angiotensin system in the tubulointerstitial injury of IgA nephropathy (IgAN)
Investigator(s):Lai KN, Leung JCK
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2004


List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Lai A.S., Cheung S.C., Tang S.C.W. and Lai K.N., Myocardial calcification following liver transplant, Chin Med J. 2014, 126.
Leung J.C.K., Lim A.I., Chan Y.Y., Yiu W.H., Lai K.N. and Tang S.C.W., Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) Represses Albumin-Induced Chemokines and Adhesion Molecules Synthesis by Kidney Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 135A.
Leung J.C.K., Lai K.N. and Tang S.C.W., Crosstalk between podocytes and tubular epithelial cells, Contrib Nephrol. 2014, 183: 54-63.
Lim A.I., Chan Y.Y., Tang S.C.W., Lai K.N. and Leung J.C.K., Albumin and Advanced Glycation Endproducts Activated KIM-1 Release by Proximal Tubular Epithelial Cells through Distinct Kinetics and Mechanism, J Am Soc Nephrol . 2013, 24: 326A.
Lim A.I., Chan Y.Y., Tang S.C.W., Yiu W.H., LI R., Lai K.N. and Leung J.C.K., BMP-7 represses albumin-induced chemokine synthesis in kidney tubular epithelial cells through destabilization of NF-κB-inducing kinase., Immunol Cell Biol.. 2014, 92(5): 427-35.
Tang S.C.W., Leung J.C.K. and Lai K.N., Crosstalk between podocytes and tubular epithelial cells, In: Z.H. Liu and J.C. He, Podocytopathy. KARGER, 2014.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
Yiu W.H., WONG W.L.D., Leung J.C.K., Chan Y.Y., Lan H.Y., Lai K.N. and Tang S.C.W., Tissue Kallikrein Mediates Pro-Inflammatory Pathways in Proximal Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 315A.
Yiu W.H., WONG W.L.D., Chan Y.Y., Leung J.C.K., Chan K.W., lan H.Y., Lai K.N. and Tang S.C.W., Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells., PLoS One. 2014, 9 (2): e88894.


Researcher : Lai KWH

List of Research Outputs

Lee Y.K., Ho W.L., Schick R., Lau V.Y.M., Lai K.W.H., Zhou T., Li Y., Ng K.M., Ho S.L., Esteban M.A., Binah O., Tse H.F. and Siu D.C.W., Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells., Pflügers Archiv - European Journal of Physiology. 2013.


Researcher : Lai YKA

List of Research Outputs

Lai Y.K.A., Lam C.M.J., Fong D.Y.T. and Ip M.S.M., Long-term efficacy of motivational interviewing on improving continuous positive airway pressure adherence in obstructive sleep apnea: A randomized controlled trial, European Respiratory Society Annual Congress, Barcelona, Spain, Sep 2013. Programme Book: p. 374 (P3595).
Lai Y.K.A., Lam C.M.J., Cheong M.Y.Y. and Ip M.S.M., The dose-response relationship between CPAP adherence and the daily performance in subjects with OSA, 18th Congress of the Asian Pacific Society of Respirologym Yokohama, Japan, Nov 2013. Respirology. 2013, 18(4): PS379.


Researcher : Lam CL

Project Title:The role of nicotinic acetylcholine receptor (nAChR) in bronchial epithelium in relation to lung carcinogenesis
Investigator(s):Lam CLD, Ip MSM, Tsao GSW, Lam WK
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2010


Project Title:Establishment of molecular tests for personalized therapy regime for lung cancer
Investigator(s):Lam CLD, Chan VNY, Ip MSM, Lee VHF
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2010


Project Title:Therapeutic target gene mutation analysis for newly established lung cancer cell lines from local Chinese patients
Investigator(s):Lam CLD
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2011


Project Title:Clinical applications of different driver mutations and biomarkers in lung cancer
Investigator(s):Lam CLD, Wan TSK
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2012


Project Title:Application of an EGFR array for the detection of Epidermal Growth Factor Receptor (EGFR) gene mutation in patients with Non-Small Cell Lung Cancer (NSCLC)
Investigator(s):Lam CLD
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


List of Research Outputs



Researcher : Lam CLD

Project Title:The role of nicotinic acetylcholine receptor (nAChR) in bronchial epithelium in relation to lung carcinogenesis
Investigator(s):Lam CLD, Ip MSM, Tsao GSW, Lam WK
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2010


Project Title:Establishment of molecular tests for personalized therapy regime for lung cancer
Investigator(s):Lam CLD, Chan VNY, Ip MSM, Lee VHF
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2010


Project Title:Therapeutic target gene mutation analysis for newly established lung cancer cell lines from local Chinese patients
Investigator(s):Lam CLD
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2011


Project Title:Clinical applications of different driver mutations and biomarkers in lung cancer
Investigator(s):Lam CLD, Wan TSK
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:09/2012


Project Title:Application of an EGFR array for the detection of Epidermal Growth Factor Receptor (EGFR) gene mutation in patients with Non-Small Cell Lung Cancer (NSCLC)
Investigator(s):Lam CLD
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


List of Research Outputs

Cooper W.A., Lam C.L.D., O'Toole S.A. and Minna J.D., Molecular biology of lung cancer, Journal of Thoracic Diseases. Pioneer Bioscience Publishing Company, 2013, 5 (Suppl 5): S479 - S490.
Lam C.L.D., Associate Editor, Respirology Case Reports. 2013.
Lam C.L.D., Clinical experience with Afatinib in EGFR mutant NSCLC patients who had failed prior treatment, Macau Chest Disease & Tuberculosis Association Scientific Meeting, Macau, 23, May, 2014. 2014.
Lam C.L.D., Chan L.K. and Ip M.S.M., Enhancement of teaching and learning with Clinical Respiratory Medicine Image MOODLE: bridging the knowledge gaps in clinical teaching, Frontiers in Medical and Health Sciences Education, December 6-7 2013, Hong Kong. 2013.
Lam C.L.D., Faculty Teaching Medal, LKS Faculty of Medicine, University of Hong Kong. 2013.
Lam C.L.D., Non-invasive ventilation in the elderly, Annual Scientific Meeting, Hong Kong Geriatrics Society. 2014.
Lam C.L.D., Respirology. 2014.
Lam C.L.D., Screening and early diagnosis of lung cancer, Annual Scientific Meeting, Hong Kong Geriatrics Society. 2014.
Lam C.L.D., Targeted Therapies and Personalized Medicine in Non-small Cell Lung Cancer, International Symposium on Respiratory Diseases (ISRD) 2013, Shanghai, China. 2013.
Lee C.Y., Lam C.L.D., Chang S.K.R., Pang Y.Y., Chang C., Lau G.K.K., Teo K.C., Ho S.L., Cheung R.T.F. and Chan K.H., Prognosis and Crisis in Generalised Myasthenia Gravis among Hong Kong Chinese, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.
Lui M.M., Tse H.F., Mak J.C.W., Lam C.M.J., Lam C.L.D., Tan K.C.B. and Ip M.S.M., Altered profile of circulating endothelial progenitor cells in obstructive sleep apnea, Sleep and Breathing. Springer, 2013, 17: 937-942.
Schraufnagel D.E., Blasi F., Drummond M.B., Lam C.L.D., Latif E., Rosen M.J., Sansores R. and Van Zyl-Smit R., Electronic Cigarettes: A Position Statement of the Forum of International Respiratory Societies., American Journal of Respiratory and Critical Care Medicine. American Thoracic Society, 2014.
Tam T.C., Ho J.C.M., Wong M.K., Wong W.M., Wang J.K., Lam J.C., Lui M.M., Lam W.K., Ip M.S.M. and Lam C.L.D., Treatment Outcomes in Elderly with Advanced-stage Non-small Cell Lung Cancer, LUNG. Springer, 2013, 191: 645 - 654.
WU L.K., Chan C.H., Mak J.C.W., Tan C., Lam C.L.D., Ip M.S.M. and Shum D.K.Y., Using Polyanionic Heparin Mimetics for the treatment of COPD, 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, June 14, 2014.


Researcher : Lam CLK

Project Title:Evaluation Study on Quality of Care of Healthcare Programmes
Investigator(s):Lam CLK, Lam TP, Chin WY, Chen JY, Lam TP
Department:Med - Family Medicine Unit
Source(s) of Funding:Hospital Authority - General Award
Start Date:04/2010


Project Title:Epidemiological Study on Different Body Constitution for the "Treatment of Not Yet ill " Programme.
Investigator(s):Lam CLK, Wong W
Department:Med - Family Medicine Unit
Source(s) of Funding:Hospital Authority - General Award
Start Date:04/2010


Project Title:Extended evaluation of quality of care of chronic disease management programmes and public-private partnership programmes of the Hospital Authority
Investigator(s):Lam CLK, Wong WCW, Chin WY, Chen JY, Fung SCC, Fong DYT, Yu YTE
Department:Family Med & Primary Care
Source(s) of Funding:Commissioned Study on Enhanced Primary Care
Start Date:07/2011


Project Title:International Society for Quality of Life Research 20th Annual Conference; Free oral paper: Health-related quality of life associated with imbalanced body constitution.
Investigator(s):Lam CLK
Department:Family Med & Primary Care
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


List of Research Outputs

CHOI P.H., Lam C.L.K., Chin W.Y., Dai D. and Kwok R., Pilot study of a multi-centre nurse-led continence care programme for management of urinary problems in primary care., 2nd NUS-NUH International Nursing Conference & 18th Singapore-Malaysia Nursing Conference. 2013.
Chan S.S.C., Leung D.Y., Leung A.Y.M., Lam C.L.K., Hung I.F.N., Chu D., Chan C.K., Johnston J.M., Liu S.H., Liang R.H.S., Lam T.H. and Yuen K.Y., A nurse-delivered brief health education intervention to improve pneumococcal vaccination rate among older patients with chronic diseases: A cluster randomized controlled trial., International journal of nursing studies. 2014.
Gangwani R.A., McGhee S., Lam C.L.K., Lai J.S.M. and Wong D.S.H., Prevalence of diabetic retinopathy and sight threatening diabetic retinopathy in Hong Kong. Are we more or less at risk?’ , Hospital Authority Convention 2014, Hong Kong . 2014.


Researcher : Lam CMJ

List of Research Outputs

Lai A.Y.K., Fong D.Y.T., Lam C.M.J., Weaver T. and Ip M.S.M., Linguistic and psychometric validation of the Chinese version of the self-efficacy measures for sleep apnea, Sleep Medicine. 2013, 14(11): 1192-1198.
Lai Y.K.A., Lam C.M.J., Fong D.Y.T. and Ip M.S.M., Long-term efficacy of motivational interviewing on improving continuous positive airway pressure adherence in obstructive sleep apnea: A randomized controlled trial, European Respiratory Society Annual Congress, Barcelona, Spain, Sep 2013. Programme Book: p. 374 (P3595).
Lai Y.K.A., Lam C.M.J., Cheong M.Y.Y. and Ip M.S.M., The dose-response relationship between CPAP adherence and the daily performance in subjects with OSA, 18th Congress of the Asian Pacific Society of Respirologym Yokohama, Japan, Nov 2013. Respirology. 2013, 18(4): PS379.
Lam C.M.J. and Ip M.S.M., OSA: Metabolic consequences: Pathophysiology and Clinical Implications, In: Patrick Levy, Electronic Book on Sleep Disordered Breathing. 2014.
Lui M.M., Tse H.F., Mak J.C.W., Lam C.M.J., Lam C.L.D., Tan K.C.B. and Ip M.S.M., Altered profile of circulating endothelial progenitor cells in obstructive sleep apnea, Sleep and Breathing. Springer, 2013, 17: 937-942.


Researcher : Lam KSL

Project Title:The Endocrine Society's 88th Annual Meeting Adipocyte Fatty Acid Binding Protein as a Potential Circulating Metabolic Hormone: Clinical and Functional Studies
Investigator(s):Lam KSL
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2006


Project Title:Obesity, adipose tissue inflammation and atherosclerosis: role of JNK activation
Investigator(s):Lam KSL, Xu A
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2011


Project Title:To Establish a Metabolic Study Centre in Hong Kong: Focusing on the Emerging Metabolic Hormones
Investigator(s):Lam KSL, Xu A, Wang Y, Cheung BMY, Wong CM
Department:Medicine
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2013


Project Title:Ageing
Investigator(s):Lam KSL, Xu A, Lum TYS
Department:Medicine
Source(s) of Funding:Seed Funding for Strategic Research Theme
Start Date:09/2013


Project Title:Establishing a Phase 1 Clinical Trials Centre in Queen Mary Hospital: Extending Hong Kong's Competitive Edges in Healthcare, Education and Life Sciences Research and Development
Investigator(s):Lam KSL, Lau YL, Cheung BMY, Lam CW, Yau HKC
Department:Medicine
Source(s) of Funding:Commissioned Programme on Phase 1 Clinical Trials Centre
Start Date:02/2014


Project Title:16th International Congress of Endocrinology cum The Endocrine Society's 96th Annual Meeting & Expo; Circulating Fibroblast Growth Factor 21 Level Predicts the Progression of Diabetic Nephropathy in Patients with Type 2 Diabetes
Investigator(s):Lam KSL
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2014


List of Research Outputs

CHEN J., Xu A., Lam K.S.L., Liu J. and Wang Y., Adiponectin deficiency promotes the development of metaplastic breast cancer-focusing on dysregulated T-cell function, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
Cheng K.Y., Lam K.S.L., WANG B. and Xu A., Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin, Best Pract Res Clin Endocrinol Metab. 2014, 28: 3-13.
Cheng K.Y., Lam K.S.L., WANG B. and Xu A., Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin, Best Practice & Research Clinical Endocrinology & Metabolism. 2013.
Cheng K.Y., Zhu W., CHEN B., Wang Y., Wu D., Sweeney G., WANG B., Lam K.S.L. and Xu A., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle, Diabetes. 2014, DB_140337: Epub ahead of print.
Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.
Cheung C.L., Cheung T.T., Lam K.S.L. and Cheung B.M.Y., High ferritin and low transferrin saturation are associated with pre-diabetes among a national representative sample of U.S. adults., Clin Nutr. 2013, 32(6): 1055-60.
Cheung C.L., Tan K.C.B., Lam K.S.L. and Cheung B.M.Y., modelling approach, 19th Medical Research Conference.Hong Kong Medical Journal. 2014, 14.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Chow W.S., Yuen M.M.A., Lee P.C.H., Woo Y.C., Tso A.W.K., Xu A., Fong H.Y., Cheung B.M.Y. and Lam K.S.L., Circulation fibroblast growth factor 21 levels predict incident hyperglycaemia in Chinese subject without the metabolic syndrome, IDF World Diabetes Congress, 2-6 Dec 2013, Melbourne, Australia. 2013.
Chow W.S., Xu A., Woo Y.C., Tso A.W.K., Cheung C.W.S., Fong H.Y., Tse H.F., Chau M.T., Cheung B.M.Y. and Lam K.S.L., Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arterioscler Thromb Vasc Biol . 2013, 33: 2454-9.
Fong D.Y.T., Rai S.N. and Lam K.S.L., Estimating the effect of multiple imputation on incomplete longitudinal data with application to a randomized clinical study, Journal of Biopharmaceutical Statistcs. 2013, 23(5): 1004-1022.
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte Fatty Acid Binding Protein Potentiates Toxic Lipids-induced Endoplasmic Reticulum Stress Via Inhibition Of JAK2-Dependent Autophagy , 12th International Congress on Obesity (ICO) . 2014.
Hoo R.L.C., SHU L., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein (A-FABP) potentiates toxic lipids-induced endoplasmic reticulum stress via suppression of JAK2-dependent autophagy, 19th Medical Research Conference. 2014.
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein potentiates palmitic acid induced endoplasmic reticulum stress in macrophages via inhibition of Janus kinase 2-dependent autophagy, Singapore Diabetes Forum 2014 . 2014.
Hoo R.L.C., Xu A. and Lam K.S.L., Adipocyte fatty acid binding proten in the pathogenesis of obesity-related nonalcoholic steatohepatitis, Asia-Pacific Diabetes & Obesity Study Group Symposium, 12-13 Oct 2013, Tokyo, Japan. 2013.
Hoo R.L.C., LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and translational (Oral Presentation), 19th Medical Research Conference. 2014.
Huang G., Yeung C.Y., Lee K.K., Liu J., Ho K.L., Yiu M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu C.W., Androgen deprivation therapy and cardiovascular risk in Chinese patients with nonmetastatic carcinoma of prostate, Journal of Oncology. 2014, Epub on 2014-04-07.
Huang G., Yeung C.Y., LEE K.K., LIU J., Ho K.L., YIU M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu D.C.W., Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate., Journal of Oncology. Hindawi, 2014, 2014.
Hui X., Gu P., Lam K.S.L. and Xu A., SIRT1 antagonizes obesity-induced vascular dysfunction via its actions in PVAT, 14th International Conference of Obesity. 2014.
Hui X., Gu P., Lam K.S.L., Vanhoutte P.M.G.R. and Xu A., SIRT1 modulates white/brown switch in PVAT, 8th Singapore Diabetes Forum. 2014.
Hui Y.L.E., Xu A., Yang H.B. and Lam K.S.L., Obesity as the common soil of non-alcoholic fatty liver disease and diabetes: Role of adipokines., J Diabetes Investig. . 2013, 4: 413-425.
Hui Y.L.E., Yeung M.C., Cheung P.T., Kwan E.Y.W., Tan K.C.B., Lam K.S.L. and Chan A.O.K., The clinical significance of aldosterone synthase deficiency: report of a novel mutation in the CYP11B2 gene., BMC Endocrine Disorder.. 2014, 14: 29.
LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and Translational (Oral Presentation), 19th Medical Research Conference. 2014.
Lam K.S.L., Hui Y.L.E., Yuen M.A.M., Yeung C.Y., Woo Y.C., Fong H.Y. and Xu A., Circulating fibroblast growth factor 21 level predicts the progression of diabetes nephropathy in patients with type 2 diabetes, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo, 17-24 Jun 2014, Chicago, USA.. 2014.
Lam K.S.L., FGF21 as a novel metabolic hormone, The 7th Oriental Congress of Endocrinology and Metabolism, 18-20 April 2014, Shanghai. 2014.
Leung A.Y.M., Lam K.S.L., Lam C.L.K., Yu Y.T.E. and Cheung M.K.T., Diabetes Risk Score smartphone application (DRS app): its application in diabetes prevention and health education, Knowledge Exchange (KE) Fund Exercise 2013/14 – Impact Project, UGC. 2013.
Leung A.Y.M., Cheung M.K.T., Yu Y.T.E., Lam C.L.K. and Lam K.S.L., The Development of a Diabetes Risk Score Smartphone Application (DRS app): views from the stakeholders, The 20th Annual Congress of Gerontology, Hong Kong Association of Gerontology, November 23, 2013. Hong Kong SAR, China.
Leung T.M., Lam K.S.L., Wong C.Y. and Khong P.L., Prevalence and factors associated with brown adipose tissue detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography in Southern Chinese, Hong Kong Journal of Radiology . 2014, 16: 183-190.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Serum Level of Sex Hormone-Binding Globulin Is a Good Independent Predictor of Metabolic Syndrome in Women with Polycystic Ovary Syndrome, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo. 2014.
Liu J., Xu A., Lam K.S.L., Wong N.S., CHEN J., Shepherd P.R. and Wang Y., Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation, Oncotarget . 2013, 4: 1804-18.
Loong C.H., Woo Y.C., Hui Y.L.E., Leung E.L., Yee S.W., Lam K.S.L. and Tan K.C.B., Advanced osteoporosis triage system shortens the waiting time for osteoporosis clinic., Health Authority Convention in Hong Kong.. 2014.
Qiu B., Shi X., Wong E.T., Lim J., Bezzi M., Low D., Zhou Q., Akıncılar S.C., Lakshmanan M., Swa H.L., Tham J.M., Gunaratne J., Cheng K.Y., Hong W., Lam K.S.L., Ikawa M., Guccione E., Xu A., Han W. and Tergaonkar V., NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling., Cell Rep.. 2014, 7: 1876-1886.
Shiu S.W.M., Xiao S., Wang Y., Chow W.S., Lam K.S.L. and Cheung B.M.Y., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clin Sci (Lond). 2014, 126: 175-81.
Shiu S.W.M., Xiao S., Wong Y., Chow W.S., Lam K.S.L. and Tan K.C.B., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clinical Science. Great Britain, 2014, 126: 175-181.
So W.Y., Cheng Q., Chen L., Evans-Molina C., Xu A., Lam K.S.L. and Leung P.S., High glucose represses beta-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: Involvement of peroxisome proliferator-activated receptor gamma signaling, Diabetes. 2013, Epub [2013 Jul 29].
WONG H.K., Ong K.L., Leung Y.H., Lam T.H., Thomas G.N., Lam K.S.L. and Cheung B.M.Y., A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels, Clinical Endocrinology. 2013, 79(4): 504-9.
Yaghootkar H., Lamina C., Scott R.A., Dastani Z., Hivert M.F., Warren L.L., Stancáková A., Buxbaum S.G., Lyytikäinen L.P., Henneman P., Wu Y., Cheung C.Y., Pankow J.S., Jackson A.U., Gustafsson S., Zhao J.H., Ballantyne C.M., Xie W., Bergman R.N., Boehnke M., El Bouazzaoui F., Collins F.S., Dunn S.H., Dupuis J., Forouhi N.G., Gillson C., Hattersley A.T., Hong J., Kähönen M., Kuusisto J., Kedenko L., Kronenberg F., Doria A., Assimes T.L., Ferrannini E., Hansen T., Hao K., Häring H., Knowles J.W., Lindgren C.M., Nolan J.J., Paananen J., Pedersen O., Quertermous T., Smith U., the GENESIS consortium .., the RISC consortium .., Lehtimäki T., Liu C.T., Loos R.J., McCarthy M., Morris A.D., Vasan R., Spector T.D., Teslovich T.M., Tuomilehto J., van Dijk K.W., Viikari J.R., Zhu N., Langenberg C., Ingelsson E., Semple R.K., Sinaiko A.R., Palmer C.N., Walker M., Lam K.S.L., Paulweber K., Mohlke K.L., van Duijn C., Raitakari O.T., Bidulescu A., Wareham N.J., Laakso M., Waterworth D.M., Lawlor D.A., Meigs J.B., Richards J.B. and Frayling T.M., Mendelian Randomisation Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes, Diabetes . 2013, 62(10): 3589-98.
Ye D., Wang Y., Li H., Jia W., Man K., Lo C.M., Wang Y., Lam K.S.L. and Xu A., Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice, Hepatology. 2014, Epub on 2014-02-06.
Yeung C.Y., Hui Y.L.E., Lam T.H., Chow W.S., Woo Y.C., Fong H.Y., Xu A., Cheung B.M.Y. and Lam K.S.L., Plasma fibrinogen level as a predictor of incident metabolic syndrome in a community-based prospective study in Hong Kong Chinese, European Association for the Study of Diabetes. 2013.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.
Yuen M., Tam S., Fong C., Chow W.S., Tan K.C.B. and Lam K.S.L., Cerebrotendinous Xanthomatosis in Seven Hong Kong Chinese., 16th International Congress of Endocrinology & the Endocrine Society's 96th Annual Meeting in Chicago, USA.. 2014.
Zhou M., PAN Y., SHU L., Lam K.S.L., Xu A. and Hoo R.L.C., Adipocyte fatty acid binding protein (A-FABP) is a potential mediator of diabetic cardiomyopathy and ischemic reperfusion induced cardiac injury , Ninth International Symposium on Healthy Aging “Aging with Confidence” . 2014.


Researcher : Lam SK

Project Title:Biotech Company in the Faculty of Medicine, The University of Hong Kong
Investigator(s):Lam SK
Department:Medicine
Source(s) of Funding:The University of Hong Kong Foundation Seed Grant
Start Date:07/2003


Project Title:Treatment of gastrointestinal cancer by targeting survivin using adeno-associated virus gene delivery system
Investigator(s):Lam SK, Wong BCY, Lin MC
Department:LKS Medical Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2004




Researcher : Lam SK

Project Title:15th World Conference on Lung Cancer; Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo
Investigator(s):Lam SK
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


Project Title:Investigation of apoptotic and E2F1 pathways induced by arsenic trioxide in non-small cell lung carcinoma
Investigator(s):Lam SK, Ho JCM
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:01/2014


List of Research Outputs

Ho J.C.M., Tam C.C.T. and Lam S.K., Personalized Treatment of Lung Adenocarcinoma, Clinical Pulmonary Medicine. 2013.
Ho J.C.M., Tam C.C.T. and Lam S.K., Salvage Therapy Beyond Targeted Therapy in Lung Adenocarcinoma, Seminars in Respiratory and Critical Care Medicine. 2013.
LI Y., Lam S.K., ZHENG C. and Ho J.C.M., The Role of Autophagy Induced by Tyrosine Kinase Inhibitors in Non-small Cell Lung Carcinoma, 15th World Conference on Lung Cancer. 2013.
LI Y., Lam S.K., ZHENG C. and Ho J.C.M., The Role of Autophagy Induced by Tyrosine Kinase Inhibitors in Non-small Cell Lung Carcinoma, 20th Hong Kong International Cancer Congress. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo , 15th World Conference on Lung Cancer. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo , 20th Hong Kong International Cancer Congress. 2013.
Lam S.K., Mak J.C.W., ZHENG C., LI Y., Kwong Y.L. and Ho J.C.M., Downregulation of thymidylate synthase with arsenic trioxide in lung adenocarcinoma, International Journal of Oncology. 2014, 44: 2093-2102.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Dual Action of Arsenic Trioxide on Thymidylate Synthase and Apoptosis in Mesothelioma , Conference on joining hands to eliminate asbestos hazards. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Dual action of arsenic trioxide on thymidylate synthase and apoptosis in mesothelioma, Conference on joining hands to eliminate asbestos hazards, Pneumoconiosis Compensation Fund Board, Hong Kong. 2013.
ZHENG C., Lam S.K., LI Y., Fong B.M., Mak J.C.W. and Ho J.C.M., Combination of arsenic trioxide and chemotherapy in small cell lung cancer, Lung Cancer. 2013, 82(2): 222-230.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, 15th World Conference on Lung Cancer. 2013.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, 20th Hong Kong International Cancer Congress. 2013.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, Journal of Thoracic Oncology. 2013, 8: S1041.


Researcher : Lam WK

List of Research Outputs

Tam T.C., Ho J.C.M., Wong M.K., Wong W.M., Wang J.K., Lam J.C., Lui M.M., Lam W.K., Ip M.S.M. and Lam C.L.D., Treatment Outcomes in Elderly with Advanced-stage Non-small Cell Lung Cancer, LUNG. Springer, 2013, 191: 645 - 654.


Researcher : Lam YM

List of Research Outputs

Yiu K.H., Wong A., Pu L., Chiang R., Sit K.Y., Chan D., Lee H.Y., Lam Y.M., Chen Y., Siu D.C.W., Lau C.P., Au K.W. and Tse H.F., Prognostic value of preoperative right ventricular geometry and tricuspid valve tethering area in patients undergoing tricuspid annuloplasty, Circulation. 2014, 129: 87-92.


Researcher : Lan HY

Project Title:Essential role of SMAD3 in cardiac repair and fibrosis
Investigator(s):Lan HY
Department:Medicine
Source(s) of Funding:Sun Chieh Yeh Heart Foundation - General Award
Start Date:08/2006


Project Title:Role of Smad signalling in the pathogenesis of hypertensive nephropathy and a novel therapeutic potential using ultrasound-microbubble-mediated transfer of inducible Smad7
Investigator(s):Lan HY
Department:Medicine
Source(s) of Funding:Baxter Health Care Ltd. - General Award
Start Date:05/2008


Project Title:Gene therapy for diabetic nephropathy using ultrasound-microbubble-mediated transfer of inducible smad7
Investigator(s):Lan HY
Department:Medicine
Source(s) of Funding:Pharmaceutical Industry - General Award
Start Date:05/2008




Researcher : Lan XR

Project Title:Mechanisms of Peritoneal Fibrosis: Role of TGF-beta Signaling
Investigator(s):Lan XR, Lan HY, Leung JCK
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2008




Researcher : Lau CP

Project Title:Evaluation of the antianginal efficacy and safety of oral chronic administration of ivabradine (5mg b.i.d. then 7.5mg b.i.d or 10mg b.i.d) compared to atenolol (50mg o.d then 100mg o.d), in patients with stable effort angina pectorals
Investigator(s):Lau CP, Lee KLF
Department:Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:05/2000


Project Title:Roles of macrophage migration inhibitory factor (MIF) in acute myocardial infarction
Investigator(s):Lau CP, Yu CM, Lan HY
Department:Medicine
Source(s) of Funding:Low Budget High Impact Programme
Start Date:11/2000


List of Research Outputs

Lau C.P., Tachapong N., Wang C.C., Wang J.F., Abe H., Kong C.W., Liew R., Shin D.G., Padeletti L., Kim Y.H., Omar R., Jirarohanakorn K., Kim Y.M., Chen M.C., Sriratanasathavorn C., Munawar M., Kam R., Chen J.Y., Cho Y.K. and Li Y.G., Prospective Randomized Study to Assess the Efficacy of Site and Rate of Atrial Pacing on Long-Term Progression of Atrial Fibrillation in Sick Sinus Syndrome: Septal Pacing for Atrial Fibrillation Suppression Evaluation (SAFE) Study., In: Joseph Loscalzo, Circulation. 2013, 128: 687-693.
Lau C.P. and Tse H.F., Response or non-response to cardiac resynchronization therapy in heart failure: Lessons from the real world., Heart Rhythm. 2014, 1147-8.
Yiu K.H., Lau G.K.K., Zhao C., Chan Y.H., Chen Y., Zhen Z., Wong A., Lau C.P. and Tse H.F., Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus, Cardiovascular Diabetology. 2014, 13:63: 1-8.
Yiu K.H., Wong A., Pu L., Chiang R., Sit K.Y., Chan D., Lee H.Y., Lam Y.M., Chen Y., Siu D.C.W., Lau C.P., Au K.W. and Tse H.F., Prognostic value of preoperative right ventricular geometry and tricuspid valve tethering area in patients undergoing tricuspid annuloplasty, Circulation. 2014, 129: 87-92.


Researcher : Lau G

Project Title:Prevalence and Natural History of Non-Alcoholic Fatty Liver Diseases in Hong Kong Chinese
Investigator(s):Lau G
Department:Medicine
Source(s) of Funding:Hong Kong Liver Foundation - General Award
Start Date:02/2005


Project Title:Basic science study on the disease mechanism, clinical surveillance and outcomes of severe hepatitis B infection
Investigator(s):Lau G
Department:Medicine
Source(s) of Funding:Matching Fund for National Key Basic Research Development Scheme (973 Projects)
Start Date:12/2007




Researcher : Lau GKK

Project Title:Prevalence and Natural History of Non-Alcoholic Fatty Liver Diseases in Hong Kong Chinese
Investigator(s):Lau G
Department:Medicine
Source(s) of Funding:Hong Kong Liver Foundation - General Award
Start Date:02/2005


Project Title:Basic science study on the disease mechanism, clinical surveillance and outcomes of severe hepatitis B infection
Investigator(s):Lau G
Department:Medicine
Source(s) of Funding:Matching Fund for National Key Basic Research Development Scheme (973 Projects)
Start Date:12/2007




Researcher : Lau GKK

Project Title:Cytochrome P450 polymorphisms and clopidogrel resistance in Chinese with ischaemic stroke
Investigator(s):Lau GKK, Chan KH, Siu DCW, Tse HF, Cheung BMY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:12/2011
Completion Date:11/2013


List of Research Outputs

Chan K.H., Lee R., Lee J.C.Y., Tse C.T.A., Pang S.Y.Y., Lau G.K.K., Teo K.C. and Ho W.L., Central nervous system inflammatory demyelinating disorders among Hong Kong Chinese, Journal of Neuroimmunology. 2013, 262: 100-105.
Lau G.K.K., Blood Pressure Variability - A Novel Risk Factor for Cardiovascular Diseases and Dementia, 19th International Symposium on Healthy Aging, Hong Kong. 2014.
Lau G.K.K., Blood Pressure Variability – A Novel Risk Factor for Cardiovascular Diseases and Dementia, Department of Social Work & Social Administration, The University of Hong Kong . 2014.
Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon S.F.K., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality, PLoS One. 2014, 9(2): e88283.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S., Hon S.F., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality., Plos One . 2014, 11:9(2): e882883.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon F.K.S., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with cancer are at increased risk of recurrent stroke and cardiovascular mortality, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., University of Oxford Croucher Scholarship, The University of Oxford and Croucher Foundation . 2014.
Lau G.K.K., Wong Y.K., Chan Y.H., Teo K.C., Chan K.H., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases – Relationships and comparisons with vascular markers of atherosclerosis, Atherosclerosis. 2014, 235(1): 230-235.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang R.S., Teo K.C., Hon S.F., Chan K.H., Wat K.L., Cheung R.T., Li L.S., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lau G.K.K., Wong Y.K., Chang R.S.K., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, European Journal of Neurology. 2014, 21(2): 319-325.
Lee C.Y., Lam C.L.D., Chang S.K.R., Pang Y.Y., Chang C., Lau G.K.K., Teo K.C., Ho S.L., Cheung R.T.F. and Chan K.H., Prognosis and Crisis in Generalised Myasthenia Gravis among Hong Kong Chinese, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drug resumption after antiplatelet-related intracerebral haemorrhage, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 40.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Siu D.C.W., Leung G.K.K., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drugs resumption after antiplatelet-related intracerebral haemorrhage in Chinese , 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelt drug resumption after antiplatelet-related intracerebral haemorrhage, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Best Free Paper Award (First Runner-up): Antiplatelet Drugs Resumption after Antiplatelet-related Intra-cerebral Haemorrhage, 14th Asian & Oceanian Congress of Neurology. 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intra-cerebral haemorrhage in Hong Kong, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intracerebral hemorrhage in Hong Kong Chinese, Neurological Research. 2014, 36: 143-149.
Tse W.S., Lau Y.M., Lai W.H., Kung H.W., Tse H.F., Lau G.K.K. and Siu D.C.W., Modelling Friedreich ataxia using patient-specific induced pluripotent stem cells, 9th International Symposium of Healthy Aging, March 2014.
Yiu K.H., Lau G.K.K., Zhao C., Chan Y.H., Chen Y., Zhen Z., Wong A., Lau C.P. and Tse H.F., Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus, Cardiovascular Diabetology. 2014, 13:63: 1-8.


Researcher : Lau KS

List of Research Outputs

Cheung C.L., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Genetic variant in vitamin D binding protein is associated with serum 25-hydroxyvitamin D and vitamin D insufficiency in southern Chinese., J Hum Genet. 51, 2013, 58: 749.
Cheung C.L., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Genetic variants in GREM2 are associated with bone mineral density in a southern Chinese population, Journal of Clinical Endocrinolog and Metabolism. 2013, 98: E1557-61.
Cheung C.L., Lau K.S., Sham P.C. and Kung A.W.C., Research Output Prize, Faculty of Medicine, the University of Hong Kong. 2013.


Researcher : Lau KW

List of Research Outputs

Mak J.C.W., Lau K.W. and Ip M.S.M., Effects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cells , 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Suppl 1): P 34 (52).


Researcher : Lau VYM

List of Research Outputs

Lee Y.K., Ho W.L., Schick R., Lau V.Y.M., Lai K.W.H., Zhou T., Li Y., Ng K.M., Ho S.L., Esteban M.A., Binah O., Tse H.F. and Siu D.C.W., Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells., Pflügers Archiv - European Journal of Physiology. 2013.


Researcher : Lau WCS

Project Title:Prospective study of the clinical pattern of systemic lupus erythematosus in Hong Kong
Investigator(s):Lau WCS
Department:Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:01/1993


Project Title:Effects of sex hormones on lymphocyte function in systemic lupus erythematosus
Investigator(s):Lau WCS, Mok TMY
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:A study to evaluate the immunopathology of Severe Acute Respiratory Syndrome
Investigator(s):Lau WCS, Chan YTE, Cheung BMY
Department:Medicine
Source(s) of Funding:VCO SARS Research Fund
Start Date:07/2003


Project Title:Evaluation of the effects of sex hormones on neutrophils and macrophage apoptosis and macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus
Investigator(s):Lau WCS
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Dendritic cell function and their effects on B cell activation in systemic lupus erythematosus
Investigator(s):Lau WCS
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:12/2005


Project Title:Interactions between plasmacytoid dendritic cells and T regulatory / interleukin-17 producing T-helper cells in systemic lupus erythematosus
Investigator(s):Lau WCS
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012


Project Title:The role of plasmacytoid dendritic cells in systemic lupus erythematosus
Investigator(s):Lau WCS, Chan VSF
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:The role of regulatory microRNAs in plasmacytoid dendritic cell functions in systemic lupus erythematosus immunopathogenesis
Investigator(s):Lau WCS, Chan VSF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


List of Research Outputs

Chan V.S.F., Yan S., TAM C.Y., Shen N. and Lau W.C.S., MicroRNA modulations in plasmacytoid dendritic cells hyperactivity in systemic lupus erythematosus, The 15th International Congress of Immunology 2013, Milan, Italy. 2013.
Kwok G., Kan A., Leung R.Y., Tam S., Lau W.C.S. and Kwong Y.L., Pyrexia, massive hepatomegaly, and extreme hyperferritinemia, Am J Med. 2014, 127(6): e13-4.
Lau W.C.S., An update in the management of ankylosing spondylitis. , Pfizer India International Speaker Program, India 28-29 June 2014. 2014.
Lau W.C.S., Chairman, Faculty Curriculum Development Committee. 2013.
Lau W.C.S., Dendritic Cell Studies in Systemic Lupus Erythematosus. , International Symposium on Immunology and Genetics of Rheumatic Diseases & National Continuing Medical Edication Workshop, Department of Rheumatology, Sun Yet Sen University, Guangzhou, December 2013. 2013.
Lau W.C.S., Evaluation of the flipped classroom in undergraduate medical teaching. , Frontiers in Medical and Health Sciences Education – HKU 2013, Hong Kong, December 2013. 2013.
Lau W.C.S., Evolving paradigm of SLE management. , Centro Januario Hospital, Macau, August 2013. 2013.
Lau W.C.S., Highlight of APLAR 2013 symposium and 2nd IJREF., Symposium of Asia Pacific League of Associations for Rheumatology (APLAR), Bali, Indonesia, August 2013. 2013.
Lau W.C.S., Interrelationship between pregnancy and autoimmune rheumatic disease. , Symposium of Asia Pacific League of Associations for Rheumatology (APLAR), Bali, Indonesia, August 2013. 2013.
Lau W.C.S., Lupus in Asia: Unmet needs. , 2nd Asian Lupus Summit and the Lupus Academy, Cebu, the Philippines, April 2014. 2014.
Lau W.C.S., Lupus research in Asia - Seizing the opportunity. , The International Symposium for Rheumatic Disease in Asia, Japan, August 2013. 2013.
Lau W.C.S., Au Y.L., Chan Y.Y., Chan Y.T., Chan O.W., Cheung T.T., Chung H.Y., Ho C.T.K., Kowk S.K., Lee W.S., Li W.L., Lui M.S., Mok T.M.Y., Tang L.M., Tsang H.L., Yuen K.Y.C. and Wong R.W.S., Outstanding Team 2014, Hong Kong West Cluster cum Queen Mary Hospital. 2014.
Lau W.C.S., Rheumatoid arthritis: Western medicine perspectives. , Seminar on Research and Development in Chinese Medicine, Hong Kong, September 2013. 2013.
Lau W.C.S., Systemic lupus erythematosus. , Chief Pharmacist’s Office, Hospital Authority, Hong Kong, January 2014. 2014.
Lau W.C.S., The JAK pathway and to facitinib mechanism of action., ASIA Reach Symposium, Hong Kong, February 2014. 2014.
Lau W.C.S., The role of anti-interleukin 6 (IL-6) in the treatment of patients with rheumatoid arthritis. , Advance Management of Rheumatic Arthritis, The Centro Hospitalar Conde de Sao Januario, Macau, January 2014. 2014.
Lau W.C.S., Training in Rheumatology in Hong Kong., 5th International Forum on Rheumatoid Arthritis, Beijing, China, September 2013. 2013.
Lau W.C.S., Unmet needs and challenges in treatment of systemic lupus erythematosus., 14th Singapore Society of Rheumatology / Malaysian Society of Rheumatology Workshop in Rheumatology, Singapore, September 2013. 2013.
Lau W.C.S., Update on systemic lupus erythematosus - Pathogenesis and treatment, , The International Symposium for Rheumatic Disease in Asia, Japan, August 2013. 2013.
Lau W.C.S., Update on the Pathogenesis of Systemic Lupus Erythematosus. , The Fall Conference of the Korean Association of Immunologists, Korea, November 2013. 2013.
Lau W.C.S., Who are the Tocilizumab Patients?, Actemra Symposium, Vietnam , September 2013. 2013.
Lin X., Rui K., Deng J., Tian J., Wang X., Wang S., Ko K.H., Jiao Z., Chan V.S.F., Lau W.C.S., Cao X. and Lu L., Th17 cells play a critical role in the development of experimental Sjogren's syndrome., Ann Rheum Dis. 2014.
Mok C.C., Tam L.S., Leung M.H., Ying K.Y., To C.H., Lee K.L., Ho L.Y., Yip M.L., Tsui H.S., Chan T.H., Lee K.W., Li E.K., Hong Kong Society of Rheumatology , Chan E.Y., Chan K.H., Chan K.M., Chan K.Y., Chan P.S., Chan Y.K., Chau S.Y., Cheung T.C., Cheung T.T., Chung H.Y., Ho C.T.K., Kun E., Kwok L.W., Kwok M.L., Kwok K., Lam C.K., Lao W.N., Lau W.C.S., Lau Y.L., Lee A.K., Lee T.K., Lee K.K., Lee M.Y., Lee S.S., Lee T.L., Yan T., Leung M.C., Li W.L., Liu H.M., Luk M.C., Ma K.Y., Mak L.W., Mok T.M.Y., Ng K.H., Ng W.L., So H., Sung C.K., Tan R.F., Tang S.K., Wan M.C., Wong C.H., Wong K.C., Man S., Wong P.Y., Wong J., Wong R.W.S., Woo W.S., Young K.Y., Yim C.W., Yu K.L., Yuen K.Y.C. and Yung K.M., Referral strategy for early recognition of axial spondyloarthritis: consensus recommendations from the Hong Kong Society of Rheumatology., Int J Rheum Dis. 2013, 16(5): 500-8.
Mok T.M.Y., Lau W.C.S. and Nikpour M., Consensus definition of a low disease activity state in systemic lupus erythematosus, International Journal of Rheumatic Diseases . 2013, 16: APLAR-0487.
Sharma N., Lau W.C.S. and Doherty I., Medical school pedagogy should be culture-dependent, Academic Medicine. 2014, 89: 194.
YAN S., YIM L.Y., Lu L., Lau W.C.S. and Chan V.S.F., MicroRNA Regulation in Systemic Lupus Erythematosus Pathogenesis., Immune Netw. 2014, 14(3): 138-48.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Lee KK

List of Research Outputs

Huang G., Yeung C.Y., Lee K.K., Liu J., Ho K.L., Yiu M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu C.W., Androgen deprivation therapy and cardiovascular risk in Chinese patients with nonmetastatic carcinoma of prostate, Journal of Oncology. 2014, Epub on 2014-04-07.


Researcher : Lee YK

List of Research Outputs

Chan Y.C., TING S., Lee Y.K., Ng K.M., Zhang J., chen Z., Siu D.C.W., oh S.K.W. and Tse H.F., Electrical Stimulation Promotes Maturation of Cardiomyocytes Derived from Human Embryonic Stem Cells, Journal of Cardiovascular Translational Research. 2013, 6: 989-999.
Lee Y.K., Ho W.L., Schick R., Lau V.Y.M., Lai K.W.H., Zhou T., Li Y., Ng K.M., Ho S.L., Esteban M.A., Binah O., Tse H.F. and Siu D.C.W., Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells., Pflügers Archiv - European Journal of Physiology. 2013.


Researcher : Lee YKM

List of Research Outputs

Lee Y.K.M., Mak J.C.W. and Ip M.S.M., Intermittent hypoxia-induced endothelial activation in EA.hy926 cells in vitro, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal . 2014, 20 (Supp 1): P.31 (46).


Researcher : Leung AYH

Project Title:Provision of free alemtuzumab (anti-CD52) to patients with chronic lymphocytic leukemia refractory to conventional chemotherapy
Investigator(s):Leung AYH, Kwong YL
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:11/2007


Project Title:Detection of WU and KI polyomaviruses from patients with acute respiratory tract infections in Hong Kong
Investigator(s):Leung AYH, Kwong YL
Department:Medicine
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:01/2009


Project Title:Provision of free service for serum polyoma BK virus quantification to kidney transplant recipients in Hong Kong
Investigator(s):Leung AYH, Kwong YL, Tang SCW
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2009


Project Title:Provision of free molecular tests for patients with acute myeloid leukemia with normal cytogenetics
Investigator(s):Leung AYH
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2010


Project Title:Provision of free sorafenib for patients with refractory or relapsed acute myeloid leukemia to bridge them to curative bone marrow transplantation
Investigator(s):Leung AYH, Kwong YL
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:07/2010


Project Title:Is sox7 a tumour suppressor in acute myeloid leukemia?
Investigator(s):Leung AYH
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Study of Microglia and Myeloid Leukemia in Zebrafish
Investigator(s):Leung AYH
Department:Medicine
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:05/2013


Project Title:A novel role of ADP-ribosylation factors-like 4a (arl4a) in definitive hematopoiesis
Investigator(s):Leung AYH
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2013


Project Title:Provision of free Sorafenib for patients with refractory or relapsed acute myeloid leukemia to bridge them to curative bone marrow transplantation
Investigator(s):Leung AYH
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2014


Project Title:Development of Cell Manipulation Tools for Probing Functional Mechanism of Hematopoietic Cells: Robotics, Optical tweezers, and Hematopoiesis
Investigator(s):Leung AYH
Department:Medicine
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2014


List of Research Outputs

Chan S.Y., Gill H., Hwang Y.Y.G., Sim J., Tse C.T.A., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Annals of Hematology. 2014, 93(3): 493-498.
Chan T.S., Gill H., Hwang Y.Y., Sim P.Y.J., Tse A.C., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Ann Hematol. 2013, Epub ahead of print.
Cheung Y.M., Leung A.Y.H., Chan S.C., Trendell-Smith N.J., So C.C. and Kwong Y.L., Fatal graft-versus-host disease after unrelated cadaveric liver transplantation due to donor/recipient human leucocyte antigen matching (Letter to the Editor), Internal Medicine Journal. 2014, 44(4): 425-426.
HE B., SHI X., Man C.H., Ma C.H., Ekker S.C., Chow C.H., So C.W., Choi W.L., Zhang W., Zhang Y. and Leung A.Y.H., Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia., Blood. USA, American Society of Hematology, 2014, 123: 2518-2529.
Kwong Y.L., Singh G.H.H., Leung A.Y.H., Tse E.W.C., Lie A.K.W., Hwang Y.Y.G., Chan T.S.Y. and Chim J.C.S., Faculty Knowledge Exchange (KE) Award 2013: 'Multi-media Haematology Protocol: Haematology Protocol Book, iPad/iPhone App, Internet Website' (Group Award) , The University of Hong Kong. 2013.
Kwong Y.L., Pang A.W.K., Leung A.Y.H., Chim J.C.S. and Tse E.W.C., Quantification of circulating Epstein-Barr virus DNA in NK/T-cell lymphoma treated with the SMILE protocol: diagnostic and prognostic significance, Leukemia. Epub ahead of print, 2013, Epub.
Lai W.Y., Li Y.Y., Mak T., HO F.C., Chow S.T., CHOOI W.H., Chow C.H., Leung A.Y.H. and Chan B.P., Reconstitution of bone-like matrix in osteogenically differentiated mesenchymal stem cells (MSC)-collagen constructs - A 3D in vitro model to study haematopoietic stem cell (HSC) niche., Journal of Tissue Engineering. 2013.
Li Y.Y., Lai W.Y., Mak T., Ho F.C., Chow S.T., CHOOI W.H., Leung A.Y.H. and Chan B.P., A 3D in vitro model to study interactions between HSCs and their niche cells. , TERMIS-AP 2013 Annual Conference. October 23-26, 2013, Shanghai-Wuzhen, P. R. China. . 2013, S12-O-2 (page 241).
MAN C.H., LAM S.Y., Sun M.K.H., Chow H.C.H., Singh G.H.H., Kwong Y.L. and Leung A.Y.H., A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML, Blood. 2014, 123: 2530-2539.
Ma C.H., SHI X., HE B., GUO Y., Wong N.S.M. and Leung A.Y.H., A novel role of Inka1 in regulating zebrafish hematopoiesis, 7th Zebrafish Disease Models Conference. 2014.
Singh G.H.H., Hwang Y.Y.G., Chan S.Y.T., Pang A.W.K., Leung A.Y.H., Tse E.W.C. and Kwong Y.L., Valganciclovir suppressed Epstein Barr virus reactivation during immunosuppression with alemtuzumab, Journal of Clinical Virology. 2014, 59: 255-258.


Researcher : Leung CTG

List of Research Outputs

Liu H., Ho W.L., Tse H.M., Leung C.T.G., Kung M.H.W., Zhou Z., Ramsden D.B. and Ho S.L., Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity , 18th International Congress of Parkinson’s Disease and Movement Disorders, June 2014, sweden.. 2014, 29.


Researcher : Leung JCK

Project Title:Renin-angiotensin system within the podocytes in IgA nephropathy
Investigator(s):Leung JCK, Lai KN
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2011


Project Title:Macrophage–Myofibroblast-Transition in Organ Fibrosis: Molecular Mechanisms and Clinical Implications
Investigator(s):Leung JCK
Department:Medicine
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2013


Project Title:The role of kidney injury molecule in the reparative process of injured kidney tubular epithelial cells
Investigator(s):Leung JCK
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Leung J.C.K., Lim A.I., Chan Y.Y., Yiu W.H., Lai K.N. and Tang S.C.W., Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) Represses Albumin-Induced Chemokines and Adhesion Molecules Synthesis by Kidney Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 135A.
Leung J.C.K., Lai K.N. and Tang S.C.W., Crosstalk between podocytes and tubular epithelial cells, Contrib Nephrol. 2014, 183: 54-63.
Lim A.I., Chan Y.Y., Tang S.C.W., Lai K.N. and Leung J.C.K., Albumin and Advanced Glycation Endproducts Activated KIM-1 Release by Proximal Tubular Epithelial Cells through Distinct Kinetics and Mechanism, J Am Soc Nephrol . 2013, 24: 326A.
Lim A.I., Chan Y.Y., Tang S.C.W., Yiu W.H., LI R., Lai K.N. and Leung J.C.K., BMP-7 represses albumin-induced chemokine synthesis in kidney tubular epithelial cells through destabilization of NF-κB-inducing kinase., Immunol Cell Biol.. 2014, 92(5): 427-35.
Tang S.C.W., Leung J.C.K. and Lai K.N., Crosstalk between podocytes and tubular epithelial cells, In: Z.H. Liu and J.C. He, Podocytopathy. KARGER, 2014.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
Yiu W.H., WONG W.L.D., Leung J.C.K., Chan Y.Y., Lan H.Y., Lai K.N. and Tang S.C.W., Tissue Kallikrein Mediates Pro-Inflammatory Pathways in Proximal Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 315A.
Yiu W.H., WONG W.L.D., Chan Y.Y., Leung J.C.K., Chan K.W., lan H.Y., Lai K.N. and Tang S.C.W., Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells., PLoS One. 2014, 9 (2): e88894.


Researcher : Leung RCY

List of Research Outputs

Cheung P.S.Y., Tong A.C., Leung R.C.Y., Kwan W.H. and Yau T.C.C., Initial experience with the Oncotype DX assay in decision-making for adjuvant therapy of early oestrogen receptor–positive breast cancer in Hong Kong, Hong Kong Medical Journal. 2014, 20.
Chiu J.W.Y., Tang Y.F., Leung R.C.Y., Wong H.Y.H., Chu K.W., Poon T.C.J., Epstein R. and Yau T.C.C., Efficacy and Tolerability of Adjuvant Oral Capecitabine plus Intravenous Oxaliplatin (XELOX) in Asian patients with Colorectal Cancer: 4-Year Analysis, Asia Pacific Journal of Cancer Prevention. 2013, 14: 6585-6590.
Kwong A., Chau W.W., Mang W.K., Wong H.N., Suen T.K.D., Leung R.C.Y., Wong K.L.M., Lee A. and Law C.K., Male breast cancer: a population-based comparison with female breast cancer in Hong Kong, Southern China: 1997–2006, Annals of Surgical Oncology. 2013, 21(4): 1246-1253.
Yau T.C.C., Leung R.C.Y., Wong H.Y.H., Chiu J.W.Y., Chan P., Tang Y.F., Cheung T.T., Pang R.W.C., Fan S.T. and Poon R.T.P., Efficacy and safety of single agent sunitinib in treating sorafenib refractory advanced hepatocellular carcinoma patients: a prospective, open-label, phase II study, The 4th Asia-Pacific Primary Liver Cancer Expert Meeting, Busan, Korea, 5-7 July 2013.


Researcher : Leung WK

Project Title:Molecular characterization of bacterial microbiota in the stomach of patients with H. pylori infection
Investigator(s):Leung WK, Woo PCY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:09/2011
Completion Date:08/2013


Project Title:A prospective randomized trial to compare the safety and immunogenicity of intradermal and intramuscular influenza vaccines in patients with inflammatory bowel disease in Hong Kong
Investigator(s):Leung WK, Hung IFN, Chan KH
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013


Project Title:Molecular characterization of gastric microbiome in individuals at different stages of H. pylori associated gastric carcinogenesis cascade
Investigator(s):Leung WK, Sham PC
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


Project Title:Detection of methylated Septin 9 DNA in blood for diagnosis, prognosis and surveillance of patients with colorectal cancer
Investigator(s):Leung WK, Shin VY
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:03/2014


List of Research Outputs

Leung W.K., Colon capsule endoscopy, Guest Lecture of the National Hospital of Sri Lanka, organized by the Sri Lanka Society of Gastroenterology, Colombo, Sri Lanka. 2014.
Leung W.K., Consensus Statements on Use of Biologics for Inflammatory Bowel Disease in Hong Kong, Annual Scientific Meeting of Macao Society of Gastroenterology & Hepatology, Macau. 2013.
Leung W.K., Lo O.S.H., Liu K.S., Tong S.M., But Y.K.D., Lam F.Y., Hsu A.S.J., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., Detection of Colorectal Adenoma by Narrow Band Imaging (HQ190) vs. High-Definition White Light Colonoscopy: A Randomized Controlled Trial, Am J Gastroenterol. 2014, 109(6): 855-63.
Leung W.K., Editorial Board Member, Helicobacter . 2014.
Leung W.K., Editorial Board Member, Helicobacter . 2014.
Leung W.K., Editorial Board Member, Journal of Digestive Diseases. 2014.
Leung W.K., Editorial Board Member, Journal of the Society of Physicians of Hong Kong. 2014.
Leung W.K., Liu K.S.H., Seto W.K.W., Chan K.H., Tong S.M., Yuen R.M.F. and Hung I.F.N., Factors for hepatitis B vaccination and abnormal liver function in Chinese patients with inflammatory bowel disease: a single center experience, J Dig Dis. 2013, 14: 596-603.
Leung W.K., GI cancer prevention, 1st Macau Medical Association Forum, Macao. 2013.
Leung W.K., How to prevent post-sphincterotomy bleeding?, Fifth Eastern Biliary-Pancreatic Endoscopy Forum, Shanghai, China. 2013.
Leung W.K., Immunomodulators in IBD: What is the best way?, the 2nd Annual Meeting of Asian Organization of Crohn’s and Colitis (AOCC2014) in Seoul, Korea. 2014.
Leung W.K., Isolated upper GI Crohn’s disease, Clinical Forum on Inflammatory Bowel Disease organized by the Asian Pacific Association of Gastroenterology and Malaysian Society of Gastroenterology and Hepatology, Penang, Malaysia. 2014.
Leung W.K., Latest Development of Pillcam Capsule Endoscopy, 2014 National Small Bowel Endoscopy Meeting organized by the Chinese Medical Association and Shanghai Digestive Endoscopy Society, Shanghai, China. 2014.
Leung W.K., Tong D.K.H., Tong S.M. and Law S.Y.K., Poster Sessions: Treatment of gastric dysplasia and metaplasia by endoscopic radiofrequency ablation: a pilot study, GASTRO 2013, Asian Pacific Digestive Week 2013 / World Congress of Gastroenterology, Shanghai, China, 21-24 September 2013.
Leung W.K., Real World Experience of Dexilant in Hong Kong, Advisory Board Meeting of Takeda Pharmaceuticals Limited, Beijing, China. 2014.
Leung W.K., Role of capsule endoscopy on acute obscure GI bleeding, 2014 National Small Bowel Endoscopy Meeting organized by the Chinese Medical Association and Shanghai Digestive Endoscopy Society, Shanghai, China. 2014.
Leung W.K., Small bowel diagnostics by advanced capsule endoscopy, SIGNEA Quadrennial Congress of the World Congress of Gastroenterology/Asia Pacific Digestive Week 2013, Shanghai, China. 2013.
Leung W.K., Tong D.K.H., Tong S.M. and Law S.Y.K., Treatment of gastric dysplasia and metaplasia by endoscopic radiofrequency ablation: a pilot study, Journal of Gastroenterology and Hepatology. 2013, 28 (Suppl 3): 68.
Leung W.K., World Journal of Gastroenterology. 2014.
Liu K.S., Hung I.F.N., Seto W.K.W., Tong S.M., Hsu A.S.J., Lam F.Y., But Y.K.D., Wong S.Y. and Leung W.K., Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial, Gut. 2013.
Liu K.S.H., Hung I.F.N., Seto W.K.W., But Y.K.D., Hsu A.S.J., Tong S.M., Chan K.H., Tan V.P.Y. and Leung W.K., Immune Responses to intramuscular or intradermal trivalent influenza vaccines in patients with inflammatory bowel disease: A randomized controlled trial, Asian Organization for Crohn's and Colitis. 2014.


Researcher : Leung YH

List of Research Outputs

WONG H.K., Ong K.L., Leung Y.H., Lam T.H., Thomas G.N., Lam K.S.L. and Cheung B.M.Y., A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels, Clinical Endocrinology. 2013, 79(4): 504-9.
WONG H.K., Leung Y.H. and Cheung B.M.Y., Effects of advanced glycation endprouducts on adrenomedullin gene expression in macrophages, 17th Annual Scientific Meeting Institute of Cardiovasclar Science and Medicine 23 November 2013, Hong Kong. 2013, 21: 69.


Researcher : Li G

Project Title:Volume-sensitive chloride current and cell volume regulation in human atrial myocytes
Investigator(s):Li GR, Lau CP, Chiu SW, Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2001


Project Title:Roles of Functional Ion Channels in Migration and Proliferation of Human Cardiac c-Kit+ Cells
Investigator(s):Li GR, Cheng LC, Li X
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2012


Project Title:58th Annual Meeting of Biophysical Society ; Store-Operated Ca2+ Entry Channels Regulate Cell Growth and Migration in Human Cardiac c-Kit+ Progenitor Cells
Investigator(s):Li GR
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:02/2014
Completion Date:02/2014


List of Research Outputs

ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.


Researcher : Li G

List of Research Outputs

ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.


Researcher : Li GR

Project Title:Volume-sensitive chloride current and cell volume regulation in human atrial myocytes
Investigator(s):Li GR, Lau CP, Chiu SW, Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2001


Project Title:Roles of Functional Ion Channels in Migration and Proliferation of Human Cardiac c-Kit+ Cells
Investigator(s):Li GR, Cheng LC, Li X
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2012


Project Title:58th Annual Meeting of Biophysical Society ; Store-Operated Ca2+ Entry Channels Regulate Cell Growth and Migration in Human Cardiac c-Kit+ Progenitor Cells
Investigator(s):Li GR
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:02/2014
Completion Date:02/2014


List of Research Outputs

CHE H., Yue J., Tse H.F. and Li G.R., Functional TRPV and TRPM channels in human preadipocytes, Pflügers Archiv - European Journal of Physiology. 2014, 466: 947-959.
Che H., Yue J., Tse H.F. and Li G.R., Functional TRPV and TRPM channels in human preadipocytes. , Pflugers Arch. . 2013.
Chen K., Sun H. and Li G.R., Acacetin is a unique natural flavone blocking multiple atrial-selective channels for anti-atrial fibrillation, Cardiac Arrhythmias 2014/The 12th IDSS on Innovations in Technology, Treatment and Prevention of Cardiac Arrhythmias, Tel Aviv, Israel. Mar 3-5.. 2014.
Chen K., Xu X.H., Liu Y., Hu Y., Jin M.W. and Li G.R., TRPM7 channels regulate proliferation and adipogenesis in 3T3-L1 Preadipocytes, J Cell Physiol. 2014, 229(1): 60-67.
Li G.R., Ultrarapid Delayed Recifier(Ikur) and Acetylcholine-Activated Potassium Channels (Ikach) as Atrial Selective Targets for AF., 6th APHRS Cardio Rhythm 2013. 3-6 Oct, Hong Kong. 2013.
Sun H., Xiao G.S., Wang Y. and Li G.R., Ionic mechanism underlying distinctive excitability in atrium and ventricle of the heart, Acta Physiologica Sinica. 2014, 66(1): 85-95.
WU W., Wang Y., Deng X.L., Sun H. and Li G.R., Cholesterol Down-Regulates BK Channels Stably Expressed in HEK 293 Cells., PLoS One. 2013, 8(11): e79952.
ZHANG Y., Yue J., CHE H., Sun H., Tse H.F. and Li G.R., BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells., J Cell Physiol. . 2013, 229(2): 202-212.
ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : Li LSW

List of Research Outputs

Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon S.F.K., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality, PLoS One. 2014, 9(2): e88283.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S., Hon S.F., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality., Plos One . 2014, 11:9(2): e882883.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon F.K.S., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with cancer are at increased risk of recurrent stroke and cardiovascular mortality, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chan Y.H., Teo K.C., Chan K.H., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases – Relationships and comparisons with vascular markers of atherosclerosis, Atherosclerosis. 2014, 235(1): 230-235.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lau G.K.K., Wong Y.K., Chang R.S.K., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, European Journal of Neurology. 2014, 21(2): 319-325.


Researcher : Li OY

List of Research Outputs

Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.


Researcher : Li RA

Project Title:Cell-based Heart Regeneration
Investigator(s):Li RA, Boheler KR, Chan BP, Chan CWY, Chan GCF, Chien KR, Lee HC, Yue J, Ng RK, Ngan AHW
Department:Medicine
Source(s) of Funding:Theme-based Research Scheme
Start Date:09/2011


Project Title:Human WT1 epicardial progenitor cells
Investigator(s):Li RA
Department:Physiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Stem Cell and Regenerative Medicine
Investigator(s):Li RA, Chan GCF, Tse HF
Department:Physiology
Source(s) of Funding:Seed Funding for Strategic Research Theme
Start Date:06/2013


Project Title:Engineering Calcium Homeostasis of hESC-derived cardiomyocytes
Investigator(s):Li RA
Department:Physiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2013




Researcher : Li TW

List of Research Outputs

Hung I.F.N., Li T.W., To K.K.W., Ho T.Y., Chan J.F.W., Chan K.H. and Yuen K.Y., Efficacy of Combined Influenza and 23-valent Polysaccharide Pneumococcal Vaccines in Chronic Smoker, Pathogenesis of Respiratory Viruses at Keystone Resort, Colorado, USA, 19-24 January 2014.


Researcher : Li X

List of Research Outputs

Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.


Researcher : Lian Q

Project Title:The Roles and Mechanisms of human mesenchymal stem cell-mediated cardial protection against anthracycline-induced cardiomyopathy
Investigator(s):Lian Q
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


Project Title:Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application
Investigator(s):Lian Q, Tse HF, Poon MW
Department:Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:01/2013


Project Title:Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application
Investigator(s):Lian Q, Tse HF, Poon MW
Department:Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:04/2013


Project Title:Generation, Purification and Transplantation of human Pluripotent Stem Cell -derived Cone and Rod Photoreceptor Cells for Retinal Degenerative Disease
Investigator(s):Lian Q, Wong DSH
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013


Project Title:International Society for Stem Cell Research 11th Annual Meeting; ACTIVATION OF NRG1/ERBB4 SIGNALING PATHYWAY IN MESENCHYMAL STEM CELLS ENHANCES CELL SURVIAL AND PARACRINE POTENTIALS AGAINST MYOCARDIAL INFARCTION
Investigator(s):Lian Q
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2013


Project Title:Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application
Investigator(s):Lian Q, Tse HF, Poon MW
Department:Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2013


Project Title:Functional roles of human ESC/iPSC-derived mesenchymal stem cell-deposited matrixes for improving survive and functions of retinal pigment epithelial cell (RPE)
Investigator(s):Lian Q
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
Lian Q., A stem cell-based platform for cardiovascular regeneration, The 1st Winter Forum on international stem cell and regenerative medicine , 2013,12.5-7 Xiamen, China. 2013.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.


Researcher : Liang RHS

List of Research Outputs

Chan S.S.C., Leung D.Y., Leung A.Y.M., Lam C.L.K., Hung I.F.N., Chu D., Chan C.K., Johnston J.M., Liu S.H., Liang R.H.S., Lam T.H. and Yuen K.Y., A nurse-delivered brief health education intervention to improve pneumococcal vaccination rate among older patients with chronic diseases: A cluster randomized controlled trial., International journal of nursing studies. 2014.


Researcher : Liang Y

List of Research Outputs

LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Liang Y., Ip M.S.M. and Mak J.C.W., Differential effects of epigallocatechin gallate on cigarette smoke-induced upregulation of CINC-1 and IL-6 in Rat H9c2 cardiomyocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Suppl 1): P 33 (50).


Researcher : Liao S

List of Research Outputs

Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.
Liao S. and Tse H.F., Multipotent (adult) and pluripotent stem cells for heart regeneration: what are the pros and cons?, Stem Cell Res Ther.. 2013, 4(6): 151.


Researcher : Lie AKW

List of Research Outputs

Chan S.Y., Gill H., Hwang Y.Y.G., Sim J., Tse C.T.A., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Annals of Hematology. 2014, 93(3): 493-498.
Chan T.S., Gill H., Hwang Y.Y., Sim P.Y.J., Tse A.C., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Ann Hematol. 2013, Epub ahead of print.
Chim J.C.S., Liu H., Lie A.K.W., Chan Y.T.E., Ho S., Wong M. and Kwong Y.L., Unsustained CR of less than 24 months after autologous stem cell transplantation predicts aggressive myeloma with short survival, Hematol Oncol. 2014, Epub ahead of print.
Kwong Y.L., Singh G.H.H., Leung A.Y.H., Tse E.W.C., Lie A.K.W., Hwang Y.Y.G., Chan T.S.Y. and Chim J.C.S., Faculty Knowledge Exchange (KE) Award 2013: 'Multi-media Haematology Protocol: Haematology Protocol Book, iPad/iPhone App, Internet Website' (Group Award) , The University of Hong Kong. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing hematopoietic stem cell transplant: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing rituximab-containing chemotherapy: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.


Researcher : Lim AI

List of Research Outputs

Leung J.C.K., Lim A.I., Chan Y.Y., Yiu W.H., Lai K.N. and Tang S.C.W., Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) Represses Albumin-Induced Chemokines and Adhesion Molecules Synthesis by Kidney Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 135A.
Lim A.I., Chan Y.Y., Tang S.C.W., Yiu W.H., LI R., Lai K.N. and Leung J.C.K., BMP-7 represses albumin-induced chemokine synthesis in kidney tubular epithelial cells through destabilization of NF-κB-inducing kinase., Immunol Cell Biol.. 2014, 92(5): 427-35.


Researcher : Liu H

List of Research Outputs

Ho W.L., Tse H.M., Liu H., Lu S., Ho W.M., Kung M.H.W., Ramsden D.B. and Ho S.L., Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System, PLoS ONE. 2013, 8(9): e74065.
Liu H., Lu S., Ho W.L., Tse H.M., Pang S.Y.Y., Kung M.H.W., Ho W.M., Ramsden D.B., Zhou Z. and Ho S.L., LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. , Annals of Clinical and Translational Neurology. 2014, 1(3): 199-208.
Liu H., Ho W.L., Tse H.M., Leung C.T.G., Kung M.H.W., Zhou Z., Ramsden D.B. and Ho S.L., Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity , 18th International Congress of Parkinson’s Disease and Movement Disorders, June 2014, sweden.. 2014, 29.


Researcher : Liu KW

List of Research Outputs

Shea Y.F., Chu L.W., Zhou L., Li W.M., Lin O.Y., Chan M.N.Y., Xu A., Wong L.C., Ho T.Y. and Liu K.W., Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Chinese Patients: A Pilot Study, American Journal of Alzheimer's Disease and Other Dementias. 2013, 28: 769-775.


Researcher : Liu S

Project Title:Rescue of post ischemic myocardial dysfunction by human induced pluripotent stem cells via cell-to-cell mitochondrial transfer
Investigator(s):Liu S, Tse HF
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013


List of Research Outputs

Chan P.H.M., Liu S., Tse H.F., Chow W.H., Jim M.H., Ho H.H. and Siu D.C.W., Long-term clinical outcomes of drug-eluting stents vs. bare-metal stents in Chinese geriatric patients, Journal of Geriatric Cardiology. 2013.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.


Researcher : Lo Y

List of Research Outputs

Mok T.M.Y., Lo Y. and Lau C.S., A needs assessment and review curriculum of content of teaching on systemic lupus erythematosus, American College of Rheumatology Congress. 2013, 2013: S414.


Researcher : Lu S

List of Research Outputs

Ho W.L., Tse H.M., Liu H., Lu S., Ho W.M., Kung M.H.W., Ramsden D.B. and Ho S.L., Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System, PLoS ONE. 2013, 8(9): e74065.
Liu H., Lu S., Ho W.L., Tse H.M., Pang S.Y.Y., Kung M.H.W., Ho W.M., Ramsden D.B., Zhou Z. and Ho S.L., LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. , Annals of Clinical and Translational Neurology. 2014, 1(3): 199-208.


Researcher : Lui OLK

Project Title:Induction of transplantation tolerance to human pluripotent stem cell-derived tissues
Investigator(s):Lui OLK, Chan CWY, Li RA
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2012
Completion Date:11/2013




Researcher : Luk JKH

List of Research Outputs

Chan C.Y.J., Hwang Y.Y.G. and Luk J.K.H., Mycosis fungoides in elderly adults--a diagnostic challenge., Journal of the American Geriatrics Society . Wiley Online Library, 2014, 62(4): 786-7.
Chan F.H., Chan T.C.I., Hung I.F.N., Luk J.K.H., Chu L.W., Ng W.C., Law T.C. and Cheng V.C.C., Early Identification of an Influenza Outbreak in a Nursing Home with High Vaccination Coverage Facilitates Implementation of Infection-Control Measures and Prevents Spreading of Influenza Infection, Journal of American Medical Directors Association. 2014, 15(4): 300-1.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Efficacy of trivalent seasonal influenza vaccination in reducing mortality and hospitalization in Chinese nursing home older adults, Journal of the American Medical Directors Association . 2013, 14: 889-894.
Chan T.C.I., Luk J.K.H., Chan F.H.W., Chu L.W. and Hung I.F.N., Factors Associated with Seasonal Influenza Vaccination in Chinese Nursing Home Older Adults , Journal of the American Medical Directors Association . 2013, 14(10): 772-774.
Chan T.C.I., Hung I.F.N., Chan K.H., Li P.Y., Li T.W., Luk J.K.H., Chu L.W. and Chan F.H.W., Immunogenicity and Safety of Intradermal Trivalent Influenza Vaccination in Nursing Home Older Adults: A Randomized Controlled Trial., Journal of American Medical Directors Association. 2014.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Inadequate Knowledge of Pneumococcal Vaccine of Nursing Home Healthcare Workers Affects the Pneumococcal Vaccination Uptake of Older Adults in Nursing Homes , Journal of the American Geriatrics Society . 2013, 61(8): 1429-1430.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Predictor of Recurrent Hospitalization in Older Adults?, Journal of the American Medical Directors Association . 2013, 14(9): 706-707.
Chan T.C.I., Hung I.F.N., Cheng V.C.C., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Is Nursing Home Residence an Independent Risk Factor of Mortality in Chinese Older Adults?, Journal of the American Geriatrics Society . 2013, 61(8): 1430-1432.
Chan T.C.I., Hung I.F.N., Luk J.K.H., Woo P.C.Y., Chu L.W. and Chan F.H.W., Prevalence of Influenza Vaccination and Associated Factors in Chinese Nursing Home Healthcare Workers, Journal of the American Geriatrics Society . 2013, 61(10): 1824-1827.
Ho A.H.Y., Luk J.K.H. and Chan F.H.W., Approaching the End-of-Life: A Systemic Discourse of Dignity and Dignified Care in Hong Kong. , 10th International Conference on Grief and Bereavement in Contemporary Society. . 2014.
Tam M.Y.J., Ho A.H.Y., Chan C.L.W., Luk J.K.H., Chan F.H.W. and Ng W.C., An Integrated Framework for Community-Based End-of-life care pathway in Hong Kong., 10th International Conference on Grief and Bereavement in Contemporary Society.. 2014.
Tam M.Y.J., Ho A.H.Y., Chan C.L.W., Luk J.K.H. and Chan H.W.F., Navigating the Last Journey: A Hong Kong EoL Pathway., ADEC 36th Annual Conference. 2014.


Researcher : MAN CH

List of Research Outputs

HE B., SHI X., Man C.H., Ma C.H., Ekker S.C., Chow C.H., So C.W., Choi W.L., Zhang W., Zhang Y. and Leung A.Y.H., Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia., Blood. USA, American Society of Hematology, 2014, 123: 2518-2529.
MAN C.H., LAM S.Y., Sun M.K.H., Chow H.C.H., Singh G.H.H., Kwong Y.L. and Leung A.Y.H., A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML, Blood. 2014, 123: 2530-2539.


Researcher : Ma CH

Project Title:The role of inka1b in zebrafish hematopoiesis
Investigator(s):Ma CH, Leung AYH
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2014


Project Title:7th Zebrafish Disease Models Conference; A novel role of Inka1 in regulating zebrafish hematopoiesis
Investigator(s):Ma CH
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2014


List of Research Outputs

HE B., SHI X., Man C.H., Ma C.H., Ekker S.C., Chow C.H., So C.W., Choi W.L., Zhang W., Zhang Y. and Leung A.Y.H., Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia., Blood. USA, American Society of Hematology, 2014, 123: 2518-2529.
Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.
Ma C.H., SHI X., HE B., GUO Y., Wong N.S.M. and Leung A.Y.H., A novel role of Inka1 in regulating zebrafish hematopoiesis, 7th Zebrafish Disease Models Conference. 2014.
Ma C.H., Efficient Genome Editing with TALEN, Joint Theme-based Research Scheme Symposium of LKS Faculty of Medicine. 2014.


Researcher : Ma KMM

List of Research Outputs

Ma K.M.M., Zuo M.L., Yap Y.H.D., Mok M.M., Kwan L.P., Chan G.C., Siu D.C.W. and Chan D.T.M., Chronotropic incompetence, echocardiographic abnormalities and exercise intolerance in renal transplant recipients., Journal of Nephrology. 2014.


Researcher : Mak JCW

Project Title:Role of transforming growth factor-beta1 variants in susceptibility to tuberculosis in Hong Kong Chinese population
Investigator(s):Mak JCW, Chan MMW
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2005


Project Title:Involvement of fatty acid-binding proteins in cigarette smoke-induced inflammatory responses in human airway epithelial cells
Investigator(s):Mak JCW
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012
Completion Date:09/2013


Project Title:Investigating the mechanisms of cigarette smoke-induced disruption of serotonin homeostasis in the airways in vitro and in vivo - relevant to chronic obstructive pulmonary disease
Investigator(s):Mak JCW
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2012


Project Title:The role of visfatin in cigarette smoke-induced inflammatory responses in human airway epithelial cells and macrophages
Investigator(s):Mak JCW
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:Biological roles of estrogen in the modulation of cigarette smoke-induced inflammation in human airway epithelial cells
Investigator(s):Mak JCW
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Chang R.C.C., Ho Y.S., WONG T.H.G., TSANG A.W.-.T., WUWONGSE S., POON C.H., YOU R., HUANG C., Ng T.W., CHENG S.Y., Hung C.H.L., LEUNG Y., Yang X., Law A.C.K., Chiu K., Lau W.M., Mak J.C.W., Wong G.T.C., Lee S.M.Y. and Hoi M.P.M., Investigating mechanisms of risk factors for Alzheimer’s disease to learn how to prevent disease progression., International Alzheimer’s Disease Conference 2014. 24.
HAN Q., Yeung S.C., Ip M.S.M. and Mak J.C.W., Cellular mechanisms in intermittent hypoxia-induced cardiac damage in vivo, J Physiol Biochem. Springer, 2014, 70: 201-213.
HAN Q., Yeung S.C., Ip M.S.M. and Mak J.C.W., Intermittent hypoxia-induced NF-kB and HO-1 regulation in human endothelial EA.hy926 cells, Cell Biochem. Biophys.. 2013, 66: 431-441.
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Lam S.K., Mak J.C.W., ZHENG C., LI Y., Kwong Y.L. and Ho J.C.M., Downregulation of thymidylate synthase with arsenic trioxide in lung adenocarcinoma, International Journal of Oncology. 2014, 44: 2093-2102.
Lee Y.K.M., Mak J.C.W. and Ip M.S.M., Intermittent hypoxia-induced endothelial activation in EA.hy926 cells in vitro, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal . 2014, 20 (Supp 1): P.31 (46).
Liang Y., Ip M.S.M. and Mak J.C.W., Differential effects of epigallocatechin gallate on cigarette smoke-induced upregulation of CINC-1 and IL-6 in Rat H9c2 cardiomyocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Suppl 1): P 33 (50).
Lui M.M., Tse H.F., Mak J.C.W., Lam C.M.J., Lam C.L.D., Tan K.C.B. and Ip M.S.M., Altered profile of circulating endothelial progenitor cells in obstructive sleep apnea, Sleep and Breathing. Springer, 2013, 17: 937-942.
Mak J.C.W., Lau K.W. and Ip M.S.M., Effects of cigarette smoke on 5-hydrotrytamine metabolism in human bronchial epithelial cells , 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Suppl 1): P 34 (52).
Mak J.C.W., Stem cell research in respiratory medicine, Update in Paediatric Respiratory Diseases 2013. 2013.
Mak J.C.W., Ho S.P., Ho A.S., Law B.K., Cheung A.H.K., Ho J.C.M., Ip M.S.M. and Chan M.M.W., Sustained elevation of systemic oxidative stress and inflammation in exacerbation and remission of asthma, ISRN Allergy. 2013, 561831.
WU L.K., Chan C.H., Mak J.C.W., Tan C., Lam C.L.D., Ip M.S.M. and Shum D.K.Y., Using Polyanionic Heparin Mimetics for the treatment of COPD, 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, June 14, 2014.
Wang Y., Yeung S.C., Ip M.S.M. and Mak J.C.W., Suppression of inflammation during adipogenic differentiation in human preadipocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Supp 1): P 42 (68).
ZHENG C., Lam S.K., LI Y., Fong B.M., Mak J.C.W. and Ho J.C.M., Combination of arsenic trioxide and chemotherapy in small cell lung cancer, Lung Cancer. 2013, 82(2): 222-230.


Researcher : Mak W

List of Research Outputs

Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.


Researcher : Man CH

Project Title:55th ASH Annual Meeting and Exposition; A Novel Role Of Tescalcin-Sodium/Hydrogen Exchange Axis Underlying Sorafenib Resistance In FLT3-ITD+ AML
Investigator(s):Man CH
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2013
Completion Date:12/2013


List of Research Outputs

HE B., SHI X., Man C.H., Ma C.H., Ekker S.C., Chow C.H., So C.W., Choi W.L., Zhang W., Zhang Y. and Leung A.Y.H., Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia., Blood. USA, American Society of Hematology, 2014, 123: 2518-2529.
MAN C.H., LAM S.Y., Sun M.K.H., Chow H.C.H., Singh G.H.H., Kwong Y.L. and Leung A.Y.H., A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML, Blood. 2014, 123: 2530-2539.


Researcher : Mok TMY

Project Title:The generation of a mouse model to study the role of IL-33 in systemic lupus erythematosus
Investigator(s):Mok TMY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:The role of IL-33 in the modulation of macrophage differentiation and immunoregulatory functions in systemic lupus erythematosus
Investigator(s):Mok TMY, Lau WCS, Chan GCF, Chan KW
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Subgingival microbiota in patients with early and established rheumatoid arthritis
Investigator(s):Mok TMY, Leung WK
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Lau W.C.S., Au Y.L., Chan Y.Y., Chan Y.T., Chan O.W., Cheung T.T., Chung H.Y., Ho C.T.K., Kowk S.K., Lee W.S., Li W.L., Lui M.S., Mok T.M.Y., Tang L.M., Tsang H.L., Yuen K.Y.C. and Wong R.W.S., Outstanding Team 2014, Hong Kong West Cluster cum Queen Mary Hospital. 2014.
Mok C.C., Tam L.S., Leung M.H., Ying K.Y., To C.H., Lee K.L., Ho L.Y., Yip M.L., Tsui H.S., Chan T.H., Lee K.W., Li E.K., Hong Kong Society of Rheumatology , Chan E.Y., Chan K.H., Chan K.M., Chan K.Y., Chan P.S., Chan Y.K., Chau S.Y., Cheung T.C., Cheung T.T., Chung H.Y., Ho C.T.K., Kun E., Kwok L.W., Kwok M.L., Kwok K., Lam C.K., Lao W.N., Lau W.C.S., Lau Y.L., Lee A.K., Lee T.K., Lee K.K., Lee M.Y., Lee S.S., Lee T.L., Yan T., Leung M.C., Li W.L., Liu H.M., Luk M.C., Ma K.Y., Mak L.W., Mok T.M.Y., Ng K.H., Ng W.L., So H., Sung C.K., Tan R.F., Tang S.K., Wan M.C., Wong C.H., Wong K.C., Man S., Wong P.Y., Wong J., Wong R.W.S., Woo W.S., Young K.Y., Yim C.W., Yu K.L., Yuen K.Y.C. and Yung K.M., Referral strategy for early recognition of axial spondyloarthritis: consensus recommendations from the Hong Kong Society of Rheumatology., Int J Rheum Dis. 2013, 16(5): 500-8.
Mok T.M.Y., Lo Y. and Lau C.S., A needs assessment and review curriculum of content of teaching on systemic lupus erythematosus, American College of Rheumatology Congress. 2013, 2013: S414.
Mok T.M.Y., Column Editor, News and Views from the APLAR region, International Journal of Rheumatic Diseases. 2014.
Mok T.M.Y., Lau W.C.S. and Nikpour M., Consensus definition of a low disease activity state in systemic lupus erythematosus, International Journal of Rheumatic Diseases . 2013, 16: APLAR-0487.
Mok T.M.Y., Current Diagnosis and Management of IgG4 related disease, The 14th Congress of Asia Pacific League of Associations of Rheumatology, Bali, Indonesia, Aug 2013. 2013.
Mok T.M.Y., Dendritic cells: Role and therapeutic implications in autoimmunity, Department of Rheumatology, The University of Tokyo, Japan. 2014.
Mok T.M.Y., Dendritic cells: Role and therapeutic implications in autoimmunity, The 15th Congress of Asia Pacific League of Associations of Rheumatology 2013, Bali, Indonesia. 2013.
Mok T.M.Y., Guest editor, Special Issue on Asian Lupus, International Journal of Rheumatic Diseases. 2014.
Mok T.M.Y., Guideline on management and treatment of rheumatoid arthritis, The Hong Kong Medical Forum, Department of Medicine, The University of Hong Kong. 2014.
Mok T.M.Y., Immunosuppressants in systemic lupus erythematosus – treatment options and potential toxicity, . Journal of the Society of Physicians of Hong Kong . 2014.
Mok T.M.Y., Management of microvascular and macrovascular disease in systemic sclerosis, The 14th Congress of Asia Pacific League of Associations of Rheumatology, Bali, Indonesia. 2013.
Mok T.M.Y., Modern approach to management and treatment of rheumatoid arthritis, University of Hong Kong Certificate Course: Management of Rheumatoid Arthritis and Limb Pain. 2014.
Mok T.M.Y., News and Views from APLAR region (June 2014), International Journal of Rheumatic Diseases. 2014.
Mok T.M.Y., News and Views from APLAR region (May 2014), International Journal of Rheumatic Diseases . 2014.
Mok T.M.Y., News and Views from the APLAR region, International Journal of Rheumatic Diseases. 2014, June 2014.
Mok T.M.Y., Pathogenesis of neuropsychiatric lupus, 6th Autoimmunity Congress Asia, Hong Kong. 2013.
Mok T.M.Y., WU H., Lau C.S. and Chan W.K., Phenotype and function of alternatively activated dendritic cells derived from patients with systemic lupus erythematosus, Annual Scientific meeting of Japan College of Rheumatology 2014, Japan. 2014.
Mok T.M.Y., Satellite Symposium: rheumatoid arthritis and tocilizumab (TCZ), The Vietnam Rheumatology Association Annual Scientific Conference, Ninh Binh, Vietnam, Nov 2013. 2013.
Mok T.M.Y., Systemic sclerosis, macro and microvascular problem and its management, The 14th Congress of Asia Pacific League of Associations of Rheumatology, Bali, Indonesia, Aug 2013. 2013.
Mok T.M.Y., Target-to-target and outcome for RA patients. Key points on consensus on biologics treatment in Rheumatoid Arthritis, The Vietnam Rheumatology Association Annual Scientific Conference, Ninh Binh, Vietnam, Nov 2013. 2013.
Mok T.M.Y. and Danda D., Treat to target for rheumatoid arthritis in 2014 – time tested triple therapy or logical biologics? , International Journal of Rheumatic Diseases . 2014, 17: 1-3.
Mok T.M.Y., Update in diagnosis and treatment of IgG4 related disease, The 14th Congress of Asia Pacific League of Associations of Rheumatology 2013, Bali, Indonesia. 2013.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : NG HY

List of Research Outputs

NG H.Y., Wan T.S.K., So J.C.C. and Chim J.C.S., Epigenetic inactivation of DAPK1, p14ARF, mir-34a and -34b/c in acute promyelocytic leukemia, Journal of Clinical Pathology. 2014, 67(6): 626-631.


Researcher : Ng KM

Project Title:Creation of a LAMP2-deficient human pluripotent stem cell-based model for studying lysosomal dysfunction induced cardiomyopathy
Investigator(s):Ng KM, Tse HF, Siu DCW
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2012
Completion Date:04/2014


Project Title:Novel Therapeutic Approach for X-linked related Danon Disease  Insight from Patient-specific Pluripotent Stem Cells Platform.
Investigator(s):Ng KM, Siu DCW, Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


List of Research Outputs

Chan Y.C., TING S., Lee Y.K., Ng K.M., Zhang J., chen Z., Siu D.C.W., oh S.K.W. and Tse H.F., Electrical Stimulation Promotes Maturation of Cardiomyocytes Derived from Human Embryonic Stem Cells, Journal of Cardiovascular Translational Research. 2013, 6: 989-999.
Lam S.S.Y., liu Y., Ng K.M., Liong E.C., Tipoe G.L., Leung P.S. and Fung M.L., Upregulation of a local renin-angiotensin system in the rat carotid body during chronic intermittent hypoxia, Experimental Physiology. 2014, 99: 220-231.
Lee Y.K., Ho W.L., Schick R., Lau V.Y.M., Lai K.W.H., Zhou T., Li Y., Ng K.M., Ho S.L., Esteban M.A., Binah O., Tse H.F. and Siu D.C.W., Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells., Pflügers Archiv - European Journal of Physiology. 2013.


Researcher : Ngai WS

List of Research Outputs

Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.


Researcher : ONG KL

List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Ong K.L., Allison M.A., Cheung B.M.Y., Wu B.J., Barter P.J. and Rye K.A., The relationship between total bilirubin levels and total mortality in older adults: the United States National Health and Nutrition Examination Survey (NHANES) 1999-2004., PLoS One. . 2014, 9(4): e94479.
WONG H.K., Ong K.L., Leung Y.H., Lam T.H., Thomas G.N., Lam K.S.L. and Cheung B.M.Y., A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels, Clinical Endocrinology. 2013, 79(4): 504-9.
WONG H.K., ONG K.L., Cheung C.L. and Cheung B.M.Y., Utilization of glucose, blood pressure, and lipid lowering medications among people with type II diabetes in the United States, 1999-2010., Ann Epidemiol. . 2014, 24(7): 516-21.


Researcher : Ong KL

List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Ong K.L., Allison M.A., Cheung B.M.Y., Wu B.J., Barter P.J. and Rye K.A., The relationship between total bilirubin levels and total mortality in older adults: the United States National Health and Nutrition Examination Survey (NHANES) 1999-2004., PLoS One. . 2014, 9(4): e94479.
WONG H.K., Ong K.L., Leung Y.H., Lam T.H., Thomas G.N., Lam K.S.L. and Cheung B.M.Y., A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels, Clinical Endocrinology. 2013, 79(4): 504-9.
WONG H.K., ONG K.L., Cheung C.L. and Cheung B.M.Y., Utilization of glucose, blood pressure, and lipid lowering medications among people with type II diabetes in the United States, 1999-2010., Ann Epidemiol. . 2014, 24(7): 516-21.


Researcher : PAN Y

List of Research Outputs

Zhou M., PAN Y., SHU L., Lam K.S.L., Xu A. and Hoo R.L.C., Adipocyte fatty acid binding protein (A-FABP) is a potential mediator of diabetic cardiomyopathy and ischemic reperfusion induced cardiac injury , Ninth International Symposium on Healthy Aging “Aging with Confidence” . 2014.


Researcher : Pan K

List of Research Outputs

KONG K.Y., Tang V.H.M., Pan K., HUANG Z., LEE T.H.J., Hinnebusch A., Jin D. and Wong C.M., Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing, Nucleic Acids Research. Oxford Journals, 2014, 42: 643-660.


Researcher : Pang AWK

List of Research Outputs

Kwong Y.L., Pang A.W.K., Leung A.Y.H., Chim J.C.S. and Tse E.W.C., Quantification of circulating Epstein-Barr virus DNA in NK/T-cell lymphoma treated with the SMILE protocol: diagnostic and prognostic significance, Leukemia. Epub ahead of print, 2013, Epub.
Singh G.H.H., Hwang Y.Y.G., Chan S.Y.T., Pang A.W.K., Leung A.Y.H., Tse E.W.C. and Kwong Y.L., Valganciclovir suppressed Epstein Barr virus reactivation during immunosuppression with alemtuzumab, Journal of Clinical Virology. 2014, 59: 255-258.


Researcher : Pang R.W.C.

Project Title:Study of a novel role of Pin1 in regulating invasiveness and metastasis of hepatocellular carcinoma via Rho signaling
Investigator(s):Pang RWC, Kwong YL, Tse EWC
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


Project Title:A study on the functional role of a novel focal adhesion protein Actopaxin and its potential regulation by Pin1 in hepatocellular carcinoma
Investigator(s):Pang RWC
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs



Researcher : Pang RWC

Project Title:Study of a novel role of Pin1 in regulating invasiveness and metastasis of hepatocellular carcinoma via Rho signaling
Investigator(s):Pang RWC, Kwong YL, Tse EWC
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2010


Project Title:A study on the functional role of a novel focal adhesion protein Actopaxin and its potential regulation by Pin1 in hepatocellular carcinoma
Investigator(s):Pang RWC
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Yau T.C.C., Leung R.C.Y., Wong H.Y.H., Chiu J.W.Y., Chan P., Tang Y.F., Cheung T.T., Pang R.W.C., Fan S.T. and Poon R.T.P., Efficacy and safety of single agent sunitinib in treating sorafenib refractory advanced hepatocellular carcinoma patients: a prospective, open-label, phase II study, The 4th Asia-Pacific Primary Liver Cancer Expert Meeting, Busan, Korea, 5-7 July 2013.


Researcher : Pang SYY

List of Research Outputs

Chan K.H., Lee R., Lee J.C.Y., Tse C.T.A., Pang S.Y.Y., Lau G.K.K., Teo K.C. and Ho W.L., Central nervous system inflammatory demyelinating disorders among Hong Kong Chinese, Journal of Neuroimmunology. 2013, 262: 100-105.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.
Liu H., Lu S., Ho W.L., Tse H.M., Pang S.Y.Y., Kung M.H.W., Ho W.M., Ramsden D.B., Zhou Z. and Ho S.L., LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. , Annals of Clinical and Translational Neurology. 2014, 1(3): 199-208.


Researcher : Ramsden DB

List of Research Outputs

Liu H., Ho W.L., Tse H.M., Leung C.T.G., Kung M.H.W., Zhou Z., Ramsden D.B. and Ho S.L., Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity , 18th International Congress of Parkinson’s Disease and Movement Disorders, June 2014, sweden.. 2014, 29.


Researcher : SAMARANAYAKE NR

List of Research Outputs

SAMARANAYAKE N.R., Cheung S.T., Cheung K., Lai K., Chui W.C. and Cheung B.M.Y., Implementing a bar-code assisted medication administration system: effects on the dispensing process and user perceptions., Int J Med Inform.. 2014, 83(6): 450-8.
SAMARANAYAKE N.R., Dabare P.R.L., Wanigatunge C.S. and Cheung B.M.Y., SLMA 126th Anniversary Sceintific Medical Congress 2013.
SAMARANAYAKE N.R., Dabare P.R., Wanigatunge C.A. and Cheung B.M.Y., The pattern of abbreviation use in prescriptions: a way forward in eliminating error-prone abbreviations and standardisation of prescriptions., Curr Drug Saf. 2014, 9(1): 34-42.


Researcher : SANG Y

List of Research Outputs

SANG Y., Yang X., Ellis-Behnke R.G., So K.F. and Cheung R.T.F., A self-assembling peptide nanofiber scaffold reduces acute brain injury and improves functional recovery in a hypertensive rat model of intracerebral hemorrhage plus clot aspiration, The Conjoint Congress of the 5th World ICH Conference 2013 & 20th Annual Scientific Meeting of Hong Kong Neurosurgical Society. 2013, 106.
SANG Y., Yang X., Su H., Leung G.K.K., Wu W. and Cheung R.T.F., Transplantation of NPCs into the hematoma cavity improves functional outcome in a rat model of intracerebral hemorrhage, The Conjoint Congress of the 5th World ICH Conference 2013 & 20th Annual Scientific Meeting of Hong Kong Neurosurgical Society. 2013, 69-70.


Researcher : SHI X

List of Research Outputs

HE B., SHI X., Man C.H., Ma C.H., Ekker S.C., Chow C.H., So C.W., Choi W.L., Zhang W., Zhang Y. and Leung A.Y.H., Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia., Blood. USA, American Society of Hematology, 2014, 123: 2518-2529.
Ma C.H., SHI X., HE B., GUO Y., Wong N.S.M. and Leung A.Y.H., A novel role of Inka1 in regulating zebrafish hematopoiesis, 7th Zebrafish Disease Models Conference. 2014.


Researcher : SHU L

List of Research Outputs

Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte Fatty Acid Binding Protein Potentiates Toxic Lipids-induced Endoplasmic Reticulum Stress Via Inhibition Of JAK2-Dependent Autophagy , 12th International Congress on Obesity (ICO) . 2014.
Hoo R.L.C., SHU L., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein (A-FABP) potentiates toxic lipids-induced endoplasmic reticulum stress via suppression of JAK2-dependent autophagy, 19th Medical Research Conference. 2014.
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein potentiates palmitic acid induced endoplasmic reticulum stress in macrophages via inhibition of Janus kinase 2-dependent autophagy, Singapore Diabetes Forum 2014 . 2014.
Hoo R.L.C., LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and translational (Oral Presentation), 19th Medical Research Conference. 2014.
LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and Translational (Oral Presentation), 19th Medical Research Conference. 2014.
Zhou M., PAN Y., SHU L., Lam K.S.L., Xu A. and Hoo R.L.C., Adipocyte fatty acid binding protein (A-FABP) is a potential mediator of diabetic cardiomyopathy and ischemic reperfusion induced cardiac injury , Ninth International Symposium on Healthy Aging “Aging with Confidence” . 2014.


Researcher : Seto WKW

Project Title:Risk of Hepatitis B Reactivation after Hematopoietic Stem Cell Transplantation in Donors and Recipients with Prior HBV Exposure
Investigator(s):Seto WKW, Kwong YL, Lie AKW, Wong DKH, Lai CL, Yuen RMF
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:02/2013


Project Title:Association between IL-1B, PSCA and MUC1 genes polymorphism with E-cadherin methylation and H. pylori infection to gastric cancer susceptibility
Investigator(s):Seto WKW, Huang FY, Chu KM, Yuen RMF, Leung WK
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


List of Research Outputs

Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Defining Normal Liver Stiffness Range in a Normal Healthy Chinese Population without Liver Disease, PLoS One. 2013, 8(12): e85067.
Fung J.Y.Y., Seto W.K.W., Lai C.L. and Yuen R.M.F., Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment, Journal of Gastroenterology and Hepatology. Blackwell Publishing, 2014, 29(3): 428-434.
Fung J.Y.Y., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Hepatitis B surface antigen levels after hepatitis B e-antigen seroclearance: a longitudinal follow-up study, Liver Int. 2014.
Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Lai C.L. and Yuen R.M.F., High Prevalence of Non-Alcoholic Fatty Liver Disease in the Chinese - Results from the Hong Kong Liver Health Census, Liver Int. 2014.
Fung J.Y.Y., Lai C.L., Wong D.K.H., Seto W.K.W., Kopaniszen M. and Yuen R.M.F., Level of hepatitis B surface antigen and not HBV DNA level after HBeAg seroclearance is predictive of HBsAg seroclearance, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S259.
Fung J.Y.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Spontaneous hepatitis B e-antigen seroconversion without subsequent antiviral therapy is associated with higher rates of hepatitis B surface antigen seroclearance, Annual Meeting, American Association for the Study of Liver Disease. 2013.
Fung J.Y.Y., Poon R.T.P., Yu W.C., Chan S.C., Chan A.C.Y., Chok K.S.H., Cheung T.T., Seto W.K.W., Lo C.M., Lai C.L. and Yuen R.M.F., Use of liver stiffness measurement for liver resection surgery: correlation with indocyanine green clearance testing and post-operative outcome, PLoS One. 2013, 8(8): e72306.
Huang F.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Estrogen represses anti-apoptotic genes expression via MiR-23a: contribution to sex differences in the development of hepatocellular carcinoma, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 667). Hepatology International. 2014, 8(S1): S243.
Huang F.Y., Wong D.K.H., Seto W.K.W., Zhang A.Y., Lee C.K., Lin C.K., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Sequence Variations of Full-Length Hepatitis B Virus Genomes in Chinese Patients with HBsAg-Negative Hepatitis B Infection, PLoS One. 2014, 9(6): e99028.
Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.
Lam Y.F., Wong D.K.H., Seto W.K.W., To K.K.W., Hung I.F.N., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., HLA-DP and interferon gamma receptor-2 gene variants and their association with viral hepatitis activity in chronic hepatitis B infection., Journal of Gastroenterology and Hepatology. 2014, 29(3): 533-539.
Leung W.K., Lo O.S.H., Liu K.S., Tong S.M., But Y.K.D., Lam F.Y., Hsu A.S.J., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., Detection of Colorectal Adenoma by Narrow Band Imaging (HQ190) vs. High-Definition White Light Colonoscopy: A Randomized Controlled Trial, Am J Gastroenterol. 2014, 109(6): 855-63.
Leung W.K., Liu K.S.H., Seto W.K.W., Chan K.H., Tong S.M., Yuen R.M.F. and Hung I.F.N., Factors for hepatitis B vaccination and abnormal liver function in Chinese patients with inflammatory bowel disease: a single center experience, J Dig Dis. 2013, 14: 596-603.
Liu K.S., Hung I.F.N., Seto W.K.W., Tong S.M., Hsu A.S.J., Lam F.Y., But Y.K.D., Wong S.Y. and Leung W.K., Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial, Gut. 2013.
Liu K.S.H., Hung I.F.N., Seto W.K.W., But Y.K.D., Hsu A.S.J., Tong S.M., Chan K.H., Tan V.P.Y. and Leung W.K., Immune Responses to intramuscular or intradermal trivalent influenza vaccines in patients with inflammatory bowel disease: A randomized controlled trial, Asian Organization for Crohn's and Colitis. 2014.
Lo O.S.H., Liu K.S.H., Tong S.M., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., New High Definition Narrow Band Imaging vs Conventional White Light Colonoscopy for Detection of Colorectal Adenomas in Symptomatic Patients: A Randomized Controlled Trial with Tandem Colonoscopy, United European Gastroenterology Week, 12-16 Oct 2013, Berlin, Germany. 2013.
Lu T., Seto W.K.W., Zhu R.X., Lai C.L. and Yuen R.M.F., Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection, World J Gastroenterol. 2013, 19(47): 8887-8894.
Nishida N., Sawai H., Kashiwase K., Minami M., Sugiyama M., Seto W.K.W., Yuen R.M.F., Posuwan N., Poovorawan Y., Ahn S.H., Han K.H., Matsuura K., Tanaka Y., Kurosaki M., Asahina Y., Izumi N., Kang J.H., Hige S., Ide T., Yamamoto K., Sakaida I., Murawaki Y., Itoh Y., Tamori A., Orito E., Hiasa Y., Honda M., Kaneko S., Mita E., Suzuki K., Hino K., Tanaka E., Mochida S., Watanabe M., Eguchi Y., Masaki N., Murata K., Korenaga M., Mawatari Y., Ohashi J., Kawashima M., Tokunaga K. and Mizokami M., New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia, PLoS One. 2014, 9(2): e86449.
Nishida N., Sawai H., Kashiwase K., Minami M., Sugiyama M., Seto W.K.W., Yuen R.M.F., Poovorawan Y., Ahn S.H., Han K.H., Matsuura K., Tanaka Y., Kurosaki M., Asahina Y., Izumi N., Kang J.H., Hige S., Ide T., Yamamoto K., Sakaida I., Murawaki Y., Itoh Y., Tamori A., Orito E., Hiasa Y., Honda M., Kaneko S., Mita E., Suzuki K., Hino K., Tanaka E., Mochida S., Watanabe M., Eguchi Y., Korenaga M., Mawatari Y., Kawashima M., Tokunaga K. and Mizokami M., Trans-ethnic analyses of HLA-DPA1, DPB1 haplotypes to be associated with hepatitis B virus infection, Poster presentation at the 64th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2013. Hepatology. 2013, 58(4)(Suppl): 102A.
Seto W.K.W., Lam Y.F., Fung J.Y.Y., Wong D.K.H., Huang F.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after five years of entecavir treatment, J Gastroenterol Hepatol. 2013, 29(5): 1028-34.
Seto W.K.W., Lam Y.F., Liu S.H.K., Mak L.Y., Ko K.L.M., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Continuous Entecavir for Treatment-Naïve Chinese Chronic Hepatitis B in the Real World Setting: The Six-Year Results, Digestive Diseases Week 2014. Gastroenterology. 2014, 146(5): Suppl 1: S963-4.
Seto W.K.W., Distinguished Young Fellow, Hong Kong Academy of Medicine. 2013.
Seto W.K.W., HBsAg and HBV DNA levels guiding entecavir cessation in HBeAg-negative chronic hepatitis B, Gastro 2013 APDW/WCOG Shanghai, Asian Pacific Digestive Week 2013 ∣ World Congress of Gastroenterology, 21-24 September 2013, Shanghai, China. Journal of Gastroenterology and Hepatology. 2013, 28(Suppl 3): 414.
Seto W.K.W., Hui A.J., Wong V.W.S., Wong G.L.H., Liu K., Lai C.L., Yuen R.M.F. and Chan H.L.Y., HBsAg and HBV DNA levels guiding entecavir cessation in HBeAg-negative chronic hepatitis B, Poster Presentation at the Gastro 2013 APDW/WCOG Shanghai, Asian Pacific Digestive Week 2013 ∣ World Congress of Gastroenterology, 21-24 September 2013, Shanghai, China. Journal of Gastroenterology and Hepatology. 2013, 28(Suppl 3): 414.
Seto W.K.W., Lai C.L. and Yuen R.M.F., Hepatitis viruses and hepatocellular carcinoma (Chapter 23), In: Prof. Shosuke Kawanishi (Suzuka University of Medical Science, Japan) and Prof. Hiroshi Ohshima (University of Shizuoka, Japan). , Cancer and Inflammation Mechanisms: Chemical, Biological and Clinical Aspects. 2014.
Seto W.K.W., Host factors predicting disease outcomes in chronic hepatitis B, State Key Laboratory for Liver Research Symposium 2013. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing hematopoietic stem cell transplant: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing rituximab-containing chemotherapy: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Journal of Gastroenterology, Pancreatology and Liver Disorders. Symbiosis Group, 2014.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Liu K.S.H., Lai C.L. and Yuen R.M.F., Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B, Clinical Microbiology and Infection. 2014.
Seto W.K.W., Tanaka Y., Shinkai N., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Performance of a highly sensitive hepatitis B surface antigen assay among chronic hepatitis B patients after hepatitis B surface antigen seroclearance, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014. (Absno. 208). Hepatology International. 2014, 8(S1): S69.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Lai C.L. and Yuen R.M.F., Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy, Hepatology. 2013, 58(3): 923-31.
Seto W.K.W., Tsang O.T., Liu K., Chan J.M., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection, Journal of Viral Hepatitis. 2013, 20(7): 470-7.
Seto W.K.W., State Key Laboratory for Liver Research Symposium 2013, 2013.
Seto W.K.W., Hui A.J., Wong V.W., Wong G.L., Liu K.S., Lai C.L., Yuen R.M.F. and Chan H.L., Treatment cessation of entecavir in Asian patients with hepatitis B e antigen negative chronic hepatitis B: a multicentre prospective study, Gut. 2014.
Seto W.K.W., Treatment endpoints in chronic hepatitis B, Liver Expert Meeting, Shenzhen 2014. 2014.
Seto W.K.W., Writing a case report, HKU-Shenzhen Medicine CME Meeting: Common Medical Conditions, New Diagnosis, Guidelines and Standardized Therapy. 2013.
Wong D.K.H., Tsoi Y.Y.O., Huang F.Y., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Application of co-amplification at lower denaturation temperature-PCR (COLD-PCR) sequencing for the early detection of antiviral drug resistance mutations of hepatitis B virus, Journal of Clinical Microbiology. 2014.
Wong D.K.H., LIN S.C., Huang F.Y., Tsoi Y.Y.O., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Association of methylated histones and DNA methylases with hepatitis B virus covalently closed circular DNA and their association with hepatitis B virus replication, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S214.
Wong D.K.H., Kopaniszen M., Omagari K., Tanaka Y., Fong D.Y.T., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Zhang A.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Effect of Hepatitis B Virus Reverse Transcriptase Variations on Entecavir Treatment Response, Journal of Infectious Diseases. 2014.
Wong D.K.H., Fung J.Y.Y., Lee C.K., Seto W.K.W., Leung J., Huang D.K.H., Lin C.K., Lai C.L. and Yuen R.M.F., Hepatitis B virus serological and virological activities in blood donors with occult hepatitis B, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 868). Hepatology International. 2014, 8(S1): S149.
Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.
Yap Y.H.D., Yung S.S.Y., Tang C.S., Seto W.K.W., Ma M.K., Mok M.M., Kwan L.P., Chan G.C., Choy B.Y., Yuen R.M.F. and Chan D.T.M., Entecavir Treatment in Kidney Transplant Recipients Infected with Hepatitis B, Clinical Transplantation. 2014.
ZHANG A., Wong D.K.H., Huang F.Y., Fung J.Y.Y., Seto W.K.W., Poon R.T.P., Lai C.L. and Yuen R.M.F., Characterization of intrahepatic HBV quasispecies genetic variability within the pre-S region in patients with HBV-related hepatocellular carcinoma, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Zheng M.H., Seto W.K.W., Shi K.Q., Wong D.K.H., Fung J.Y.Y., Hung I.F.N., Fong D.Y.T., Yuen J.C.H., Tong T., Lai C.L. and Yuen R.M.F., Artificial neural network accurately predicts hepatitis B surface antigen seroclearance, PLoS One. 2014, 9(6): e99422.


Researcher : Shek SYN

List of Research Outputs

Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Efficacy of high-intensity focused ultrasonography for noninvasive body sculpting in Chinese patients., Lasers in Surgery and Medicine. Wiley Online Library, 2014, 46(4): 263-9.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Efficiacy of a High-Intensity Focused Ultrasound Device for Non-invasive Body Contouring, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Non-invasive Cryolipolysis for Fat Reduction in Flanks in Chinese with a Modified Applicator , 19th Medical research Conference; Department of Medicine; Li KA Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Safety and Efficacy Evaluation of a Combined Device Using Infrred Light and Bi-polar Radiofrequency and Sublative Radiofrequency Applicators, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., The Efficacy of a Microwave Device for Treating Hyperhidrosis in Chinese, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.


Researcher : Shen J

Project Title:Biochemical Society Meeting 679 University of Essex UK - Stress, Signalling and Control Reactive Oxygen Species Mediate Intracellular Cholesterol Accumulation via Modulating Caveolin-1 Pathway in Chinese Hamster Ovary Cells
Investigator(s):Shen J
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2003


Project Title:Elucidating caveolin-1 as a negative modulating protein for proliferation of neural stem/progenitor cells and neural differentiation in post-ischemic brain
Investigator(s):Shen J, Chung SK, So KF
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2010


Project Title:Molecular regulations of reactive nitrogen species inhibitors for preventing thrombolysis-induced blood brain barrier disruption and hemorrhagic transformation in experimental cererbal ischemia-reperfersion models
Investigator(s):Shen J, Cheung RTF, Chung SK, Siu DCW, Yang D
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating proliferation and neuronal differentiation of neural stem/progenitor cells under hypoxic and ischemic conditions
Investigator(s):Shen J, Yang D, So KF
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012
Completion Date:10/2013


Project Title:Using Ski as a molecular target for seeking active compounds from Qingyihuaji (QYHJ) formula for inhibiting pancreatic cancer stem cells
Investigator(s):Shen J, Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2012
Completion Date:01/2014


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating proliferation and neuronal differentiation of neural stem/progenitor cells under hypoxic and ischemic conditions
Investigator(s):Shen J, Chung SK, So KF, Yang D
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2012


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating neurogenesis under hypoxic and ischemic conditions
Investigator(s):Shen J, Yang D, Chen X
Department:School of Chinese Medicine
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2013


Project Title:Effects of endosomal adaptor protein for regulating cell fate decision during differentiation of neural stem/progenitor cells
Investigator(s):Shen J, So KF, Chung SK
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013
Completion Date:04/2014


Project Title:Elucidating effects of APPL2 on regulating proliferation and cell fate decision of neural stem/progenitor cells through activating Notch signaling pathway
Investigator(s):Shen J, So KF, Chung SK
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Gordon Conference on Oxygen Radicals ; NITRIC OXIDE/CAVEOLIN-1/MATRIX METALLOPROTEINASES SIGNALING CASCADES IS A CRUCIAL PATHWAY IN BLOOD BRAIN BARRIER DISRUPTION DURING CEREBRAL ISCHEMIA-REPERFUSION INJURY
Investigator(s):Shen J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:02/2014
Completion Date:02/2014


Project Title:Roles of Caveolin-1 in Regulating T lymphocytes Infiltration through Blood Brain Barrier in Pathological Process of Experimental Autoimmune Encephalomyelitis
Investigator(s):Shen J, Chan GCF, Wu W
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014




Researcher : Shiu SWM

List of Research Outputs

Shiu S.W.M., Xiao S., Wang Y., Chow W.S., Lam K.S.L. and Cheung B.M.Y., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clin Sci (Lond). 2014, 126: 175-81.
Shiu S.W.M., Xiao S., Wong Y., Chow W.S., Lam K.S.L. and Tan K.C.B., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clinical Science. Great Britain, 2014, 126: 175-181.
TSUN G.S., Shiu S.W.M., Wong Y., Yung S.S.Y., Chan D.T.M. and Tan K.C.B., Impact of serum amyloid A on cellular cholesterol efflux to serum in type 2 diabetes mellitus., Atherosclerosis.. 2013, 231: 405-10.
Tan K.C.B., Lee A.C., Lam J.K., Shiu S.W.M. and Wong Y., Association between Soluble Receptor for Advanced Glycation End Products and A Disintegrin And Metalloproteinase 10 in Type 1 Diabetes., 16th International Congress of Endocrinology and the Endocrine Society's 96th Annual Meeting in Chicago, USA.. 2014.
Tan K.C.B., TSUN G.S., Yung S.S.Y., Chau K.M., Shiu S.W.M. and Chan D.T.M., Cholesterol transport proteins and diabetic nephropathy., World Diabetes Congress in Melbourne, Australia.. 2013.


Researcher : Sim PYJ

List of Research Outputs

Chan T.S., Gill H., Hwang Y.Y., Sim P.Y.J., Tse A.C., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Ann Hematol. 2013, Epub ahead of print.


Researcher : Singh GHH

List of Research Outputs

MAN C.H., LAM S.Y., Sun M.K.H., Chow H.C.H., Singh G.H.H., Kwong Y.L. and Leung A.Y.H., A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML, Blood. 2014, 123: 2530-2539.
Singh G.H.H., Hwang Y.Y.G., Chan S.Y.T., Pang A.W.K., Leung A.Y.H., Tse E.W.C. and Kwong Y.L., Valganciclovir suppressed Epstein Barr virus reactivation during immunosuppression with alemtuzumab, Journal of Clinical Virology. 2014, 59: 255-258.


Researcher : Siu DCW

Project Title:Dynamic Conformational Changes of the P-S6 linker of the Pacemaker (HCN) Channels Identified by Sulfhydryl Modification: Pore-to-Gate Coupling Model
Investigator(s):Siu DCW, Tse HF
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:10/2008


Project Title:Human Induced Pluripotent Stem Cells as a Disease Modeling and Drug Screening Platform for Friedreich Ataxia
Investigator(s):Siu DCW, Ho WL, Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2012


Project Title:Cardiac fibroblasts derived Human induced pluripotent cells for cardiac regeneration
Investigator(s):Siu DCW, Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


List of Research Outputs

Chan P.H.M., Liu S., Tse H.F., Chow W.H., Jim M.H., Ho H.H. and Siu D.C.W., Long-term clinical outcomes of drug-eluting stents vs. bare-metal stents in Chinese geriatric patients, Journal of Geriatric Cardiology. 2013.
Chan Y.C., TING S., Lee Y.K., Ng K.M., Zhang J., chen Z., Siu D.C.W., oh S.K.W. and Tse H.F., Electrical Stimulation Promotes Maturation of Cardiomyocytes Derived from Human Embryonic Stem Cells, Journal of Cardiovascular Translational Research. 2013, 6: 989-999.
Guo Y., Chung S.K., Siu D.C.W., Kwan S.C., Ho W.L., Yeung P.K.K., Teo K.C. and Chan K.H., Endothelin-1 overexpression exacerbate experimental allergic encephalomyelitis, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong. 2014.
Huang G., Yeung C.Y., LEE K.K., LIU J., Ho K.L., YIU M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu D.C.W., Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate., Journal of Oncology. Hindawi, 2014, 2014.
Jim M.H., Fung R.C., Yiu K.H., Ng A.K., Siu D.C.W. and Fan K.Y., Combined Paclitaxel-Eluting Balloon and Genous Cobalt-Chromium Alloy Stent Utilization in De Novo Coronary Stenoses (PEGASUS). , J Interv Cardiol. . 2013, 26(5): 556-560.
Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon S.F.K., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality, PLoS One. 2014, 9(2): e88283.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S., Hon S.F., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality., Plos One . 2014, 11:9(2): e882883.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon F.K.S., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with cancer are at increased risk of recurrent stroke and cardiovascular mortality, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chan Y.H., Teo K.C., Chan K.H., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases – Relationships and comparisons with vascular markers of atherosclerosis, Atherosclerosis. 2014, 235(1): 230-235.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang R.S., Teo K.C., Hon S.F., Chan K.H., Wat K.L., Cheung R.T., Li L.S., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lau G.K.K., Wong Y.K., Chang R.S.K., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, European Journal of Neurology. 2014, 21(2): 319-325.
Lee Y.K., Ho W.L., Schick R., Lau V.Y.M., Lai K.W.H., Zhou T., Li Y., Ng K.M., Ho S.L., Esteban M.A., Binah O., Tse H.F. and Siu D.C.W., Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells., Pflügers Archiv - European Journal of Physiology. 2013.
Lo C.Y., Tjong Y.W., Ho J.C.Y., Siu D.C.W., Yue S., Tse H.F. and Yao X., An upregulated expression of vanilloid transient potential channels 2 enhances the hypo-osmolarity induced cytosolic calcium elevation in human induced pluripotent stem cells model of Hutchinson-Gillford Progeria Syndrome., PloS One. 2014, 9: e87273.
Ma K.M.M., Zuo M.L., Yap Y.H.D., Mok M.M., Kwan L.P., Chan G.C., Siu D.C.W. and Chan D.T.M., Chronotropic incompetence, echocardiographic abnormalities and exercise intolerance in renal transplant recipients., Journal of Nephrology. 2014.
Siu D.C.W., 2013 Interviewee, The Standard “A survey conducted by specialists in the Netherlands which say that sleeping for more than 7 hours a day helps to prevent heart disease. . 2013.
Siu D.C.W., Frequent premature atrial complexes... truly a benign finding? Author Reply. , Europace . 2013, 15: 306-307.
Siu D.C.W., Invited Speaker, Asian Interchange on Diabetes Seoul, Korea, “ Unravelling the relationship between diabetes and cardiovascular diseases”, 2014.
Siu D.C.W., Invited Speaker,“中國杭州人胚胎干细胞治疗心肌梗死的基础和临床应用关键科学问题研究” , 2014.
Siu D.C.W., 2013 Interviewee, China Daily interview request: Deep Vein Thrombosis. 2013.
Siu D.C.W., 2013 Invited Speaker, Asian Interchange on Diabetes Seoul, Korea, “ Unravelling the relationship between diabetes and cardiovascular diseases”, 2013.
Siu D.C.W., 2013 Invited Speaker, Lecture for Macau cardiologists, Macau “ New Pharmacological Treatment in Acute Heart Failure”, 2013.
Siu D.C.W., 2013 Invited Speaker, Thrombosis Academy, Philippines “ Background of AF, risk factors of AF and the balance between bleeding (ICH) and stroke, data on aspirin and effectiveness in stroke”, 2013.
Siu D.C.W., 2013 Speaker, Public health talk “細心聆聽 –更,「脂」你「心」” co-organized by Hong Kong College of Cardiology. 2013.
Siu D.C.W., 2014 Interviewee , Oriental Daily, Treatment for Nonmetastatic Carcinoma of Prostate . 2014.
Siu D.C.W., 2014 Interviewee , RTHK "Doctor and You 2014" - 心律不正. 2014.
Siu D.C.W., 2014 Interviewee, Carnation - Health Education at Headline Daily”三低一高的飲食文化”. 2014.
Siu D.C.W., 2014 Public Talk, The Jockey Club ‘Heart Safe School’ “Hennessy Road Government Primary School . 2014.
Siu D.C.W., 2014 Public Talk, The Jockey Club “Heart-Safe School Project”. 2014.
Siu D.C.W., 2014 Public Talk” HKU Faculty, " HKU Successfully performs the First implantation of a newly developed defibrillator in Asia”. 2014.
Siu D.C.W., Chairperson ,The 16th South China International Congress of Cardiology, Guangzhou China , 心脏起搏论坛:起搏专场 . 2014.
Siu D.C.W., Invited Speaker Scientific Sessions of World Congress of Cardiology, Melbourne, Australia , Supraventricular Arrhythmias: New insights and real-life challenges. 2014.
Siu D.C.W., Invited Speaker, The Macau Cardiology Annual Scientific Meeting,”, Outcomes of Antithrombotic Therapies in SPAF Insights from a local registry. 2014.
Siu D.C.W., Invited Speaker, Lecture for Macau cardiologists, Macau “ New Pharmacological Treatment in Acute Heart Failure”, 2014.
Siu D.C.W., Invited Speaker, Lecture for Venice Arrhythmias 2013, Venice Italy, “ Genetic differences in AF susceptibility, 2013.
Siu D.C.W., Invited Speaker, Thrombosis Academy, Philippines “ Stroke Prevention with Antiplatelets Controversy or Consensus?”, 2014.
Siu D.C.W. and Tse H.F., Net clinical benefit of warfarin therapy in elderly Chinese patients with atrial fibrillation., Circulation. LWW, 2014, 7(2): 300-306.
Siu D.C.W., Lip G.Y., Lam K.F. and Tse H.F., Risk of stroke and intracranial hemorrhage in 9,727 chinese with atrial fibrillation in Hong Kong., Heart Rhythm. 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drug resumption after antiplatelet-related intracerebral haemorrhage, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 40.
Teo K.C., Lau G.K.K., Lee R., Chang S.K.R., Siu D.C.W., Leung G.K.K., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelet drugs resumption after antiplatelet-related intracerebral haemorrhage in Chinese , 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Antiplatelt drug resumption after antiplatelet-related intracerebral haemorrhage, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Teo K.C., Lau G.K.K., Lee R., Chang S.K., Leung G.K.K., Siu D.C.W., Cheung R.T.F., Ho S.L. and Chan K.H., Best Free Paper Award (First Runner-up): Antiplatelet Drugs Resumption after Antiplatelet-related Intra-cerebral Haemorrhage, 14th Asian & Oceanian Congress of Neurology. 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intra-cerebral haemorrhage in Hong Kong, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Teo K.C., Mahboobani N.R., Lee R., Siu D.C.W., Cheung R.T.F., Ho S.L., Lau G.K.K. and Chan K.H., Warfarin associated intracerebral hemorrhage in Hong Kong Chinese, Neurological Research. 2014, 36: 143-149.
Tse W.S., Lau Y.M., Lai W.H., Kung H.W., Tse H.F., Lau G.K.K. and Siu D.C.W., Modelling Friedreich ataxia using patient-specific induced pluripotent stem cells, 9th International Symposium of Healthy Aging, March 2014.
Yiu K.H., Yeung C.K., Zhao C., Chan J.C., Siu D.C.W., Tam S., Wong C.S., Yan G.H., Yue W.S., Khong P.L., Cha H. and Tse H.F., Prevalence and extent of subclinical atherosclerosis in patients with psoriasis, J Intern Med. 2013, 3: 273-282.
Yiu K.H., Wong A., Pu L., Chiang R., Sit K.Y., Chan D., Lee H.Y., Lam Y.M., Chen Y., Siu D.C.W., Lau C.P., Au K.W. and Tse H.F., Prognostic value of preoperative right ventricular geometry and tricuspid valve tethering area in patients undergoing tricuspid annuloplasty, Circulation. 2014, 129: 87-92.
ZHANG J., Ho J.C.Y., Chan Y.C., Lian Q., Siu D.C.W. and Tse H.F., Overexpression of myocardin induces partial transdifferentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells into cardiomyocytes, Physiological Reports. 2014, 2: n/a-n/a.
Zuo M., Yue W., Yip T., Ng F., Lam K.F., Yiu K.H., Lui S.L., Tse H.F., Siu D.C.W. and Lo W.K., Prevalence of and Associations With Reduced Exercise Capacity in Peritoneal Dialysis Patients, In: Andrew S. Levey, Daniel E. Weiner, American Journal of Kidney Diseases. Elsevier, 2013, 62: 939-946.


Researcher : Siu SC

List of Research Outputs

Wong C.K.H., Fung S.C.C., Siu S.C., Lo Y.C.Y., Wong K.W., Fong D.Y.T. and Lam C.L.K., A short message service (SMS) intervention to prevent diabetes in Chinese professional drivers with pre-diabetes: A pilot single-blinded randomized controlled trial, Diabetes Research and Clinical Practice. 2013, 102 (3): 158-166.


Researcher : Sun H

List of Research Outputs

Chen K., Sun H. and Li G.R., Acacetin is a unique natural flavone blocking multiple atrial-selective channels for anti-atrial fibrillation, Cardiac Arrhythmias 2014/The 12th IDSS on Innovations in Technology, Treatment and Prevention of Cardiac Arrhythmias, Tel Aviv, Israel. Mar 3-5.. 2014.
Sun H., Xiao G.S., Wang Y. and Li G.R., Ionic mechanism underlying distinctive excitability in atrium and ventricle of the heart, Acta Physiologica Sinica. 2014, 66(1): 85-95.
WU W., Wang Y., Deng X.L., Sun H. and Li G.R., Cholesterol Down-Regulates BK Channels Stably Expressed in HEK 293 Cells., PLoS One. 2013, 8(11): e79952.
ZHANG Y., Yue J., CHE H., Sun H., Tse H.F. and Li G.R., BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells., J Cell Physiol. . 2013, 229(2): 202-212.
ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : TAM CY

List of Research Outputs

Chan V.S.F., Yan S., TAM C.Y., Shen N. and Lau W.C.S., MicroRNA modulations in plasmacytoid dendritic cells hyperactivity in systemic lupus erythematosus, The 15th International Congress of Immunology 2013, Milan, Italy. 2013.


Researcher : TSUN GS

List of Research Outputs

TSUN G.S., Shiu S.W.M., Wong Y., Yung S.S.Y., Chan D.T.M. and Tan K.C.B., Impact of serum amyloid A on cellular cholesterol efflux to serum in type 2 diabetes mellitus., Atherosclerosis.. 2013, 231: 405-10.
Tan K.C.B., TSUN G.S., Yung S.S.Y., Chau K.M., Shiu S.W.M. and Chan D.T.M., Cholesterol transport proteins and diabetic nephropathy., World Diabetes Congress in Melbourne, Australia.. 2013.


Researcher : Tam CCT

List of Research Outputs

Ho J.C.M., Tam C.C.T. and Lam S.K., Personalized Treatment of Lung Adenocarcinoma, Clinical Pulmonary Medicine. 2013.
Ho J.C.M., Tam C.C.T. and Lam S.K., Salvage Therapy Beyond Targeted Therapy in Lung Adenocarcinoma, Seminars in Respiratory and Critical Care Medicine. 2013.


Researcher : Tam S

List of Research Outputs

Yiu K.H., Yeung C.K., Zhao C., Chan J.C., Siu D.C.W., Tam S., Wong C.S., Yan G.H., Yue W.S., Khong P.L., Cha H. and Tse H.F., Prevalence and extent of subclinical atherosclerosis in patients with psoriasis, J Intern Med. 2013, 3: 273-282.


Researcher : Tan C

List of Research Outputs

WU L.K., Chan C.H., Mak J.C.W., Tan C., Lam C.L.D., Ip M.S.M. and Shum D.K.Y., Using Polyanionic Heparin Mimetics for the treatment of COPD, 2014 Hong Kong Inter-University Biochemistry Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, June 14, 2014.


Researcher : Tan KCB

Project Title:Advanced glycation end product receptors in diabetes
Investigator(s):Tan KCB
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Genetic Screening of Familial Hypercholesterolemia in Hong Kong
Investigator(s):Tan KCB, Yeung CY, Siu DCW, Leung JYY, Pang HK, Cheung CL
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2014


List of Research Outputs

CHAU T.K., Chan S.S.C., Wong J.Y.H., Fong D.Y.T., Li W.H.C., Leung A.Y.M., Tan K.C.B. and Lam T.H., Smoking Behaviors in Patients with Type 2 Diabetes Mellitus: A Qualitative Study, 18th Research Postgraduate Symposium, Faculty of Medicine, The University of Hong Kong, December 11,2013. .
Cheung C.L., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Genetic variant in vitamin D binding protein is associated with serum 25-hydroxyvitamin D and vitamin D insufficiency in southern Chinese., J Hum Genet. 51, 2013, 58: 749.
Cheung C.L., Lau K.S., Sham P.C., Tan K.C.B. and Kung A.W.C., Genetic variants in GREM2 are associated with bone mineral density in a southern Chinese population, Journal of Clinical Endocrinolog and Metabolism. 2013, 98: E1557-61.
Cheung C.L., Tan K.C.B., Lam K.S.L. and Cheung B.M.Y., modelling approach, 19th Medical Research Conference.Hong Kong Medical Journal. 2014, 14.
Cheung E., Kung A.W.C. and Tan K.C.B., Outcomes of applying the NOF, NOGG and Taiwanese guidelines to a cohort of Chinese early postmenopausal women., Clinical endocrinology (Oxford). 2014, 80: 200-7.
Hui Y.L.E., Yeung M.C., Cheung P.T., Kwan E.Y.W., Tan K.C.B., Lam K.S.L. and Chan A.O.K., The clinical significance of aldosterone synthase deficiency: report of a novel mutation in the CYP11B2 gene., BMC Endocrine Disorder.. 2014, 14: 29.
Leung E.L., Yeung C.Y., Yee A.S., Leung C.Y., Wong Y.F., Wong K.K. and Tan K.C.B., Effectiveness of a nurse-led treatment intensification program in treating type 2 DM patient with poor glycaemic control., Health Authority Convention in Hong Kong.. 2014.
Loong C.H., Woo Y.C., Hui Y.L.E., Leung E.L., Yee S.W., Lam K.S.L. and Tan K.C.B., Advanced osteoporosis triage system shortens the waiting time for osteoporosis clinic., Health Authority Convention in Hong Kong.. 2014.
Loong C.H., Woo Y.C., Hui Y.L.E. and Tan K.C.B., Simple risk assessment tools to identify post-menopausal women with fracture risk in community., 15th Regional Osteoporosis Conference.. 2014.
Lui M.M., Tse H.F., Mak J.C.W., Lam C.M.J., Lam C.L.D., Tan K.C.B. and Ip M.S.M., Altered profile of circulating endothelial progenitor cells in obstructive sleep apnea, Sleep and Breathing. Springer, 2013, 17: 937-942.
Shiu S.W.M., Xiao S., Wong Y., Chow W.S., Lam K.S.L. and Tan K.C.B., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clinical Science. Great Britain, 2014, 126: 175-181.
TSUN G.S., Shiu S.W.M., Wong Y., Yung S.S.Y., Chan D.T.M. and Tan K.C.B., Impact of serum amyloid A on cellular cholesterol efflux to serum in type 2 diabetes mellitus., Atherosclerosis.. 2013, 231: 405-10.
Tan K.C.B., Lee A.C., Lam J.K., Shiu S.W.M. and Wong Y., Association between Soluble Receptor for Advanced Glycation End Products and A Disintegrin And Metalloproteinase 10 in Type 1 Diabetes., 16th International Congress of Endocrinology and the Endocrine Society's 96th Annual Meeting in Chicago, USA.. 2014.
Tan K.C.B., TSUN G.S., Yung S.S.Y., Chau K.M., Shiu S.W.M. and Chan D.T.M., Cholesterol transport proteins and diabetic nephropathy., World Diabetes Congress in Melbourne, Australia.. 2013.
Tan K.C.B., DPP-4 Inhibitor FDC Use in Type 2 Diabetes: New Approaches for Meeting Unmet Needs., Macau Physician Society Symposium in Macau.. 2014.
Tan K.C.B., Diagnosis and Treatment of Polycystic Ovary Syndrome., Guangdong Province CME Meeting for Physicians in Shenzhen.. 2014.
Tan K.C.B., How to make sense of the New cholesterol Guidelines., Annual Scientific Meeting of the Federation of Medical Societies of Hong Kong.. 2014.
Tan K.C.B., Pre-diabetes perspective in Hong Kong., Asia Pacific Regional Pre-diabetes Meeting in Manila.. 2014.
Tan K.C.B., Update on Diabetic Nephropathy., Macau Physician Society Annual Scientific Meeting in Macau.. 2013.
Woo Y.C., Loong N.H.C., Hui Y.L.E., Leung E., Kung A.W.C. and Tan K.C.B., History- an physical examination-based model showed good discrimination ability in fracture prediction., World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Disease in Seville.. 2014.
Xiao S.M., Kung A.W.C., Sham P.C. and Tan K.C.B., Genetic analysis of recently identified osteoporosis susceptibility genes in southern Chinese., Journal of Clinical Endocrinology and Metabolism. 2013, 98: 1827-34.
Yuen M., Tam S., Fong C., Chow W.S., Tan K.C.B. and Lam K.S.L., Cerebrotendinous Xanthomatosis in Seven Hong Kong Chinese., 16th International Congress of Endocrinology & the Endocrine Society's 96th Annual Meeting in Chicago, USA.. 2014.


Researcher : Tan V.P.Y.

Project Title:Prevalence of Fermentable Oligo-, Di- and Mono- saccharides and Polyols (FODMAPS) malabsorption in Chinese Control, Functional Dyspepsia, Irritable Bowel and Inflammatory Bowel Disease Patients
Investigator(s):Tan VPY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:Influence of phytochemicals present in plant based supplementation on stool microbiota of control versus colon cancer subjects: A feasibility study
Investigator(s):Tan VPY, Panagiotou I, Dufay S, Poon TCJ
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs



Researcher : Tan VPY

Project Title:Prevalence of Fermentable Oligo-, Di- and Mono- saccharides and Polyols (FODMAPS) malabsorption in Chinese Control, Functional Dyspepsia, Irritable Bowel and Inflammatory Bowel Disease Patients
Investigator(s):Tan VPY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:Influence of phytochemicals present in plant based supplementation on stool microbiota of control versus colon cancer subjects: A feasibility study
Investigator(s):Tan VPY, Panagiotou I, Dufay S, Poon TCJ
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Liu K.S.H., Hung I.F.N., Seto W.K.W., But Y.K.D., Hsu A.S.J., Tong S.M., Chan K.H., Tan V.P.Y. and Leung W.K., Immune Responses to intramuscular or intradermal trivalent influenza vaccines in patients with inflammatory bowel disease: A randomized controlled trial, Asian Organization for Crohn's and Colitis. 2014.


Researcher : Tang CW

Project Title:Provision of free mycophenolate mofetil for IgA nephropathy patients with persistent proteinuria despite maximal angiotensin blockade therapy in Hong Kong
Investigator(s):Tang SCW, Lai KN
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Aliskiren combined with losartan in immunoglobulin A nephropathy: an open-label pilot study
Investigator(s):Tang SCW, Lai KN
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:10/2010


Project Title:Exploring the role of the kallikrein-kinin system in diabetic nephropathy
Investigator(s):Tang SCW, Yiu WH
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Potential therapeutic role of bone marrow-derived mesenchymal stromal/stem cells in diabetic nephropathy
Investigator(s):Tang SCW, Yiu WH
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012
Completion Date:11/2013


Project Title:King's/HKU Fellowship Awards 2012-13
Investigator(s):Tang SCW
Department:Medicine
Source(s) of Funding:King's/HKU Fellowship Awards
Start Date:07/2012


Project Title:Exploring the role of bone marrow-derived mesenchymal stromal/stem cells in nephropathies
Investigator(s):Tang SCW, Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:ISN Forefronts Symposium on 'Stem Cells and Kidney Regeneration'; Potential role of embryonic stem cell-derived microvesicles in kidney repair
Investigator(s):Tang SCW
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2013
Completion Date:09/2013


Project Title:Wnt/beta-catenin signaling in kidney proximal tubular cells
Investigator(s):Tang SCW
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs



Researcher : Tang SCW

Project Title:Provision of free mycophenolate mofetil for IgA nephropathy patients with persistent proteinuria despite maximal angiotensin blockade therapy in Hong Kong
Investigator(s):Tang SCW, Lai KN
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Aliskiren combined with losartan in immunoglobulin A nephropathy: an open-label pilot study
Investigator(s):Tang SCW, Lai KN
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:10/2010


Project Title:Exploring the role of the kallikrein-kinin system in diabetic nephropathy
Investigator(s):Tang SCW, Yiu WH
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Potential therapeutic role of bone marrow-derived mesenchymal stromal/stem cells in diabetic nephropathy
Investigator(s):Tang SCW, Yiu WH
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012
Completion Date:11/2013


Project Title:King's/HKU Fellowship Awards 2012-13
Investigator(s):Tang SCW
Department:Medicine
Source(s) of Funding:King's/HKU Fellowship Awards
Start Date:07/2012


Project Title:Exploring the role of bone marrow-derived mesenchymal stromal/stem cells in nephropathies
Investigator(s):Tang SCW, Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:ISN Forefronts Symposium on 'Stem Cells and Kidney Regeneration'; Potential role of embryonic stem cell-derived microvesicles in kidney repair
Investigator(s):Tang SCW
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2013
Completion Date:09/2013


Project Title:Wnt/beta-catenin signaling in kidney proximal tubular cells
Investigator(s):Tang SCW
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Lai A.S., Cheung S.C., Tang S.C.W. and Lai K.N., Myocardial calcification following liver transplant, Chin Med J. 2014, 126.
Leung J.C.K., Lim A.I., Chan Y.Y., Yiu W.H., Lai K.N. and Tang S.C.W., Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) Represses Albumin-Induced Chemokines and Adhesion Molecules Synthesis by Kidney Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 135A.
Leung J.C.K., Lai K.N. and Tang S.C.W., Crosstalk between podocytes and tubular epithelial cells, Contrib Nephrol. 2014, 183: 54-63.
Lim A.I., Chan Y.Y., Tang S.C.W., Lai K.N. and Leung J.C.K., Albumin and Advanced Glycation Endproducts Activated KIM-1 Release by Proximal Tubular Epithelial Cells through Distinct Kinetics and Mechanism, J Am Soc Nephrol . 2013, 24: 326A.
Lim A.I., Chan Y.Y., Tang S.C.W., Yiu W.H., LI R., Lai K.N. and Leung J.C.K., BMP-7 represses albumin-induced chemokine synthesis in kidney tubular epithelial cells through destabilization of NF-κB-inducing kinase., Immunol Cell Biol.. 2014, 92(5): 427-35.
Lin M. and Tang S.C.W., Toll-like receptors: sensing and reacting to diabetic injury in the kidney, Nephrol Dial Transplant. 2014, 29(4): 746-54.
Tang S.C.W., A journey from Guy’s Hospital and back, Guest speaker, Renal Unit Seminar, Guy’s Hospital, King’s College London (London, UK). 2013.
Tang S.C.W., American Journal of Nephrology, Editorial Board. KARGER, 2014.
Tang S.C.W., Leung J.C.K. and Lai K.N., Crosstalk between podocytes and tubular epithelial cells, In: Z.H. Liu and J.C. He, Podocytopathy. KARGER, 2014.
Tang S.C.W., Current treatment in IgAN, lupus and other nephritis, Associacao de Nefrologia de Macau (Macau Society of Nephrology). 2014.
Tang S.C.W., Diabetes and the Kidney, Department of Internal medicine, Kaohsiung Chang Gung Memorial Hospital (Taiwan) . 2013.
Tang S.C.W., Diabetic nephropathy and proximal tubular damage, 8th International Congress of Uremia Research and Toxicity (Okinawa, Japan). 2014.
Tang S.C.W., Diabetic tubular injury, Guest speaker at the Centre for Nephrology, Royal Free Hospital, University College London (London, UK). 2013.
Tang S.C.W., It’s all about inflammation: the tubulointerstitium in diabetic nephropathy, American Society of Nephrology Kidney Week (Atlanta, GA, USA). 2013.
Tang S.C.W., Lipid Management in CKD Patients, 9th International Symposium on Healthy Aging “Aging with Confidence” Symposium (Hong Kong). 2014.
Tang S.C.W., Mediators of Inflammation, Guest Editor. Hindawi Publishing Corporation, 2014.
Tang S.C.W., Nephrology Dialysis Transplantation, Editorial Board. Oxford University Press, 2013.
Tang S.C.W., Nephrology Dialysis Transplantation, Theme and Subspecialties Editor (Clinical Nephrology and Diabetes). Oxford University Press, 2014.
Tang S.C.W., Novel targets in diabetic nephropathy, Sun Yat-sen International Forum on Bio-Medicine (Guangzhou, China). 2013.
Tang S.C.W., Renal Regeneration in proteinuric CKD, 14th Asian Pacific Congress of Nephrology (Tokyo, Japan). 2014.
Tang S.C.W., Role of Toll-like receptors in nephropathies, Chinese Society of Nephrology (Fuzhou, China). 中华医学会肾脏病学分会2013年学术年会, 2013.
Tang S.C.W., Sleep quality in PD patients, 6th International Society for Peritoneal Dialysis-Asian Chapter Meeting (Taipei, Taiwan). 2013.
Tang S.C.W., TSC Case Presentations in Renal Angiolipoma, Multidisciplinary and Integrated Approach to Tuberous Sclerosis (Paris, France). 2013.
Tang S.C.W., 育醫造才: 探索醫學世界 第三冊, 香港大學李嘉城醫學院, 2014.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
Yiu W.H., WONG W.L.D., Leung J.C.K., Chan Y.Y., Lan H.Y., Lai K.N. and Tang S.C.W., Tissue Kallikrein Mediates Pro-Inflammatory Pathways in Proximal Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 315A.
Yiu W.H., WONG W.L.D., Chan Y.Y., Leung J.C.K., Chan K.W., lan H.Y., Lai K.N. and Tang S.C.W., Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells., PLoS One. 2014, 9 (2): e88894.


Researcher : Tang YF

List of Research Outputs

Chiu J.W.Y., Tang Y.F., Leung R.C.Y., Wong H.Y.H., Chu K.W., Poon T.C.J., Epstein R. and Yau T.C.C., Efficacy and Tolerability of Adjuvant Oral Capecitabine plus Intravenous Oxaliplatin (XELOX) in Asian patients with Colorectal Cancer: 4-Year Analysis, Asia Pacific Journal of Cancer Prevention. 2013, 14: 6585-6590.
Yau T.C.C., Leung R.C.Y., Wong H.Y.H., Chiu J.W.Y., Chan P., Tang Y.F., Cheung T.T., Pang R.W.C., Fan S.T. and Poon R.T.P., Efficacy and safety of single agent sunitinib in treating sorafenib refractory advanced hepatocellular carcinoma patients: a prospective, open-label, phase II study, The 4th Asia-Pacific Primary Liver Cancer Expert Meeting, Busan, Korea, 5-7 July 2013.


Researcher : Tiu TMRJ

List of Research Outputs

Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.


Researcher : Tjong YW

List of Research Outputs

Lo C.Y., Tjong Y.W., Ho J.C.Y., Siu D.C.W., Yue S., Tse H.F. and Yao X., An upregulated expression of vanilloid transient potential channels 2 enhances the hypo-osmolarity induced cytosolic calcium elevation in human induced pluripotent stem cells model of Hutchinson-Gillford Progeria Syndrome., PloS One. 2014, 9: e87273.


Researcher : Tong SM

List of Research Outputs

Leung W.K., Lo O.S.H., Liu K.S., Tong S.M., But Y.K.D., Lam F.Y., Hsu A.S.J., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., Detection of Colorectal Adenoma by Narrow Band Imaging (HQ190) vs. High-Definition White Light Colonoscopy: A Randomized Controlled Trial, Am J Gastroenterol. 2014, 109(6): 855-63.
Leung W.K., Liu K.S.H., Seto W.K.W., Chan K.H., Tong S.M., Yuen R.M.F. and Hung I.F.N., Factors for hepatitis B vaccination and abnormal liver function in Chinese patients with inflammatory bowel disease: a single center experience, J Dig Dis. 2013, 14: 596-603.
Leung W.K., Tong D.K.H., Tong S.M. and Law S.Y.K., Poster Sessions: Treatment of gastric dysplasia and metaplasia by endoscopic radiofrequency ablation: a pilot study, GASTRO 2013, Asian Pacific Digestive Week 2013 / World Congress of Gastroenterology, Shanghai, China, 21-24 September 2013.
Leung W.K., Tong D.K.H., Tong S.M. and Law S.Y.K., Treatment of gastric dysplasia and metaplasia by endoscopic radiofrequency ablation: a pilot study, Journal of Gastroenterology and Hepatology. 2013, 28 (Suppl 3): 68.
Liu K.S., Hung I.F.N., Seto W.K.W., Tong S.M., Hsu A.S.J., Lam F.Y., But Y.K.D., Wong S.Y. and Leung W.K., Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial, Gut. 2013.
Liu K.S.H., Hung I.F.N., Seto W.K.W., But Y.K.D., Hsu A.S.J., Tong S.M., Chan K.H., Tan V.P.Y. and Leung W.K., Immune Responses to intramuscular or intradermal trivalent influenza vaccines in patients with inflammatory bowel disease: A randomized controlled trial, Asian Organization for Crohn's and Colitis. 2014.
Lo O.S.H., Liu K.S.H., Tong S.M., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., New High Definition Narrow Band Imaging vs Conventional White Light Colonoscopy for Detection of Colorectal Adenomas in Symptomatic Patients: A Randomized Controlled Trial with Tandem Colonoscopy, United European Gastroenterology Week, 12-16 Oct 2013, Berlin, Germany. 2013.


Researcher : Tse CTA

List of Research Outputs

Chan K.H., Lee R., Lee J.C.Y., Tse C.T.A., Pang S.Y.Y., Lau G.K.K., Teo K.C. and Ho W.L., Central nervous system inflammatory demyelinating disorders among Hong Kong Chinese, Journal of Neuroimmunology. 2013, 262: 100-105.
Chan S.Y., Gill H., Hwang Y.Y.G., Sim J., Tse C.T.A., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Annals of Hematology. 2014, 93(3): 493-498.
Lee J.C.Y., Pang S.Y.Y., Lam C.L.D., Tse C.T.A., Lau G.K.K., Chang S.K.R., Ho S.L., Cheung R.T.F., Mak W., Hon F.K.S., Chang C.K.L., Teo K.C. and Chan K.H., Myasthenic crisis in patients with generalised myasthenia gravis, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 30.


Researcher : Tse EWC

Project Title:Outstanding Young Researcher Award 2009-10
Investigator(s):Tse EWC
Department:Medicine
Source(s) of Funding:Outstanding Young Researcher Award
Start Date:12/2010


Project Title:Enhancing the anti-leukaemia effect of arsenic tiroxide by dexamethasone
Investigator(s):Tse EWC
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2012
Completion Date:10/2013


Project Title:PIN1 and CKS proteins cooperate in the regulation of cell cycle progression
Investigator(s):Tse EWC
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:01/2013


Project Title:Extending the therapeutic application of arsenic trioxide in acute myeloid leukaemia
Investigator(s):Tse EWC, Kwong YL
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


List of Research Outputs

Chan S.Y., Gill H., Hwang Y.Y.G., Sim J., Tse C.T.A., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Annals of Hematology. 2014, 93(3): 493-498.
Chan S.Y.T., Kwong Y.L. and Tse E.W.C., Novel therapeutic agents for T-cell lymphomas, Discovery Medicine. 2013, 16(86): 27-35.
Chan T.S., Gill H., Hwang Y.Y., Sim P.Y.J., Tse A.C., Loong F., Khong P.L., Tse E.W.C., Leung A.Y.H., Chim J.C.S., Lie A.K.W. and Kwong Y.L., Breakthrough invasive fungal diseases during echinocandin treatment in high-risk hospitalized hematologic patients, Ann Hematol. 2013, Epub ahead of print.
Cheng C.W., Kwong Y.L. and Tse E.W.C., Best Abstract in Basic Science & Translational (Poster), 19th Medical Research Conference Department of Medicine, HKU. 2014.
Kwong Y.L., Singh G.H.H., Leung A.Y.H., Tse E.W.C., Lie A.K.W., Hwang Y.Y.G., Chan T.S.Y. and Chim J.C.S., Faculty Knowledge Exchange (KE) Award 2013: 'Multi-media Haematology Protocol: Haematology Protocol Book, iPad/iPhone App, Internet Website' (Group Award) , The University of Hong Kong. 2013.
Kwong Y.L., Pang A.W.K., Leung A.Y.H., Chim J.C.S. and Tse E.W.C., Quantification of circulating Epstein-Barr virus DNA in NK/T-cell lymphoma treated with the SMILE protocol: diagnostic and prognostic significance, Leukemia. Epub ahead of print, 2013, Epub.
Singh G.H.H., Hwang Y.Y.G., Chan S.Y.T., Pang A.W.K., Leung A.Y.H., Tse E.W.C. and Kwong Y.L., Valganciclovir suppressed Epstein Barr virus reactivation during immunosuppression with alemtuzumab, Journal of Clinical Virology. 2014, 59: 255-258.
Tse E.W.C., Leung R.Y.Y. and Kwong Y.L., Invasive fungal infections after obinutuzumab monotherapy for refractory chronic lymphocytic leukemia, Annals of Hematology. 2014.
Tse E.W.C. and Kwong Y.L., Management of Advanced NK/T-Cell Lymphoma, Current Hematologic Malignancy Reports. 2014.
Tse E.W.C., Sir David Todd Lectureship, The Hong Kong College of Physicians. 2013.
WANG L., Kwong Y.L., Wong K.F., Kho C.S.B., Jin D., Tse E.W.C., Rosen A. and Chim J.C.S., Epigenetic inactivation of miR-34b/c in addition to miR-34a and DAPK1 in chronic lymphocytic leukemia, J Transl Med. 2014, 12(1): 52.
Wang L.Q., Kwong Y.L., Wong K.F., Kho C.S.B., Jin D., Tse E.W.C., Rosen A. and Chim J.C.S., Epigenetic inactivation of miR-34b/c in addition to miR-34a and DAPK1 in chronic lymphocytic leukemia, Journal of Translational Medicine. 2014, 12: 52-61.
Yeoh A.E., Tan D., Li C.K., Hori H., Tse E.W.C. and Pui C.H., Management of adult and paediatric acute lymphoblastic leukaemia in Asia: resource-stratified guidelines from the Asian Oncology Summit 2013, The Lancet Oncology. 2013, 14: e508-e523.


Researcher : Tse HF

Project Title:Direct intramyocardial implantation of autologous bone marrow cells for enhancement of neovascularization in patients with "End-Staged" coronary artery disease
Investigator(s):Tse HF, Lau CP, Kwong YL
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2004


Project Title:Outstanding Researcher Award 2007-2008
Investigator(s):Tse HF
Department:Medicine
Source(s) of Funding:Outstanding Researcher Award
Start Date:10/2008


Project Title:Direct endomyocardial injection of autologous bone marrow cells for treatment of patients with "end-stage" ischaemic heart failure
Investigator(s):Tse HF, Lau CP, Kwong YL, Siu DCW, Lee SWL, Chan HWF, Lam L, Lee KLF, Chan WS, Lam YM
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2009


Project Title:Attenuation of Left Ventricular Remodeling and Improvement of Myocardial Function with Spinal Cord Stimulation in Post-myocardial Infarction Heart Failure
Investigator(s):Tse HF, Siu DCW, Wang MM, Yiu KH
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:07/2011
Completion Date:07/2013


Project Title:Personalized Medicine for Cardiovascular Diseases: From Genomic Testing and Biomarkers to Human Pluripotent Stem Cell Platform
Investigator(s):Tse HF, Xu A, Sham PC, Lam KSL, Lam TH, Cheung BMY, Tan KCB, Siu DCW, Lian Q, Cherny SS, Lam CW
Department:Medicine
Source(s) of Funding:Theme-based Research Scheme
Start Date:01/2012


Project Title:Therapeutic Effects and Mechanism of Sympathorenal Axis Modulation by Catheter-based Renal Denervation in Porcine Model of Ischemic Heart Failure
Investigator(s):Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Targeted gene correction and disease modeling using Wilson's disease induced pluripotent stem cells
Investigator(s):Tse HF, Ho JCY
Department:Medicine
Source(s) of Funding:NSFC/RGC Joint Research Scheme
Start Date:01/2013


Project Title:Viral-Vector Integration-Free Human Induced Pluripotent Stem Cells Platform Derived from Urine Samples for Disease Diagnosis and Drug Screening
Investigator(s):Tse HF, Ho JCY, Lai KWH
Department:Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:07/2013


Project Title:Effects of Catheter-based Splanchnic Denervation on Blood Pressure Control and Left Ventricular Remodeling in Porcine Model of Hypertensive Cardiomyopathy
Investigator(s):Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


List of Research Outputs

CHE H., Yue J., Tse H.F. and Li G.R., Functional TRPV and TRPM channels in human preadipocytes, Pflügers Archiv - European Journal of Physiology. 2014, 466: 947-959.
Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.
Chan P.H.M., Liu S., Tse H.F., Chow W.H., Jim M.H., Ho H.H. and Siu D.C.W., Long-term clinical outcomes of drug-eluting stents vs. bare-metal stents in Chinese geriatric patients, Journal of Geriatric Cardiology. 2013.
Chan Y.C., TING S., Lee Y.K., Ng K.M., Zhang J., chen Z., Siu D.C.W., oh S.K.W. and Tse H.F., Electrical Stimulation Promotes Maturation of Cardiomyocytes Derived from Human Embryonic Stem Cells, Journal of Cardiovascular Translational Research. 2013, 6: 989-999.
Che H., Yue J., Tse H.F. and Li G.R., Functional TRPV and TRPM channels in human preadipocytes. , Pflugers Arch. . 2013.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Chow W.S., Xu A., Woo Y.C., Tso A.W.K., Cheung C.W.S., Fong H.Y., Tse H.F., Chau M.T., Cheung B.M.Y. and Lam K.S.L., Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arterioscler Thromb Vasc Biol . 2013, 33: 2454-9.
Huang G., Yeung C.Y., Lee K.K., Liu J., Ho K.L., Yiu M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu C.W., Androgen deprivation therapy and cardiovascular risk in Chinese patients with nonmetastatic carcinoma of prostate, Journal of Oncology. 2014, Epub on 2014-04-07.
Huang G., Yeung C.Y., LEE K.K., LIU J., Ho K.L., YIU M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu D.C.W., Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate., Journal of Oncology. Hindawi, 2014, 2014.
Kumana C.R., Cheung B.M.Y. and Tse H.F., Relative versus absolute drug-therapy benefits and safety: Lessons from ARISTOTLE, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 25.
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Lau C.P. and Tse H.F., Response or non-response to cardiac resynchronization therapy in heart failure: Lessons from the real world., Heart Rhythm. 2014, 1147-8.
Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Long-term prognostic implications of visit-to-visit blood pressure variability in patients with ischaemic stroke, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 28.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon S.F.K., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality, PLoS One. 2014, 9(2): e88283.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S., Hon S.F., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality., Plos One . 2014, 11:9(2): e882883.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon F.K.S., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke patients with cancer are at increased risk of recurrent stroke and cardiovascular mortality, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chan Y.H., Teo K.C., Chan K.H., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases – Relationships and comparisons with vascular markers of atherosclerosis, Atherosclerosis. 2014, 235(1): 230-235.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon F.K.S., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 29.
Lau G.K.K., Wong Y.K., Chang R.S., Teo K.C., Hon S.F., Chan K.H., Wat K.L., Cheung R.T., Li L.S., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lau G.K.K., Wong Y.K., Chang R.S.K., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, European Journal of Neurology. 2014, 21(2): 319-325.
Lee Y.K., Ho W.L., Schick R., Lau V.Y.M., Lai K.W.H., Zhou T., Li Y., Ng K.M., Ho S.L., Esteban M.A., Binah O., Tse H.F. and Siu D.C.W., Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells., Pflügers Archiv - European Journal of Physiology. 2013.
Liao S. and Tse H.F., Multipotent (adult) and pluripotent stem cells for heart regeneration: what are the pros and cons?, Stem Cell Res Ther.. 2013, 4(6): 151.
Lo C.Y., Tjong Y.W., Ho J.C.Y., Siu D.C.W., Yue S., Tse H.F. and Yao X., An upregulated expression of vanilloid transient potential channels 2 enhances the hypo-osmolarity induced cytosolic calcium elevation in human induced pluripotent stem cells model of Hutchinson-Gillford Progeria Syndrome., PloS One. 2014, 9: e87273.
Lui M.M., Tse H.F., Mak J.C.W., Lam C.M.J., Lam C.L.D., Tan K.C.B. and Ip M.S.M., Altered profile of circulating endothelial progenitor cells in obstructive sleep apnea, Sleep and Breathing. Springer, 2013, 17: 937-942.
Siu D.C.W. and Tse H.F., Net clinical benefit of warfarin therapy in elderly Chinese patients with atrial fibrillation., Circulation. LWW, 2014, 7(2): 300-306.
Siu D.C.W., Lip G.Y., Lam K.F. and Tse H.F., Risk of stroke and intracranial hemorrhage in 9,727 chinese with atrial fibrillation in Hong Kong., Heart Rhythm. 2014.
Ting S., Lecina M., Chan Y.C., Tse H.F., Reuveny S. and Oh S.K., Nutrient supplemented serum-free medium increases cardiomyogenesis efficiency of human pluripotent stem cells. , World J Stem Cells.. 2013, 5: 86-97.
Tse H.F., Invited Speaker, AF Global Advisory Board, Tokyo Japan,” Real world and current standard care in AF patients –regional perspectives, 2014.
Tse H.F., Invited Speaker, ESC 2013, Netherlands, 2013.
Tse H.F., The 6th Ventricular Arrhythmia Symposium of China, Nanjing, China” “ Future device therapy for heart failure and ventricular arrhythmias”, 2014.
Tse H.F., Chair, 2014 Asia- Pacific Cardiovascular Symposium Guangzhou, China,” Beta Blockers for Management of Cardiovascular diseases: are all beta-blockers the same?”, 2014.
Tse H.F., Chair, Cardiostim 2014, Nice, France, “ Meet the Experts”Using CHADS2-VASC and has bled in everyday clinical practice, 2014.
Tse H.F., Chair, Heart Rhythm 2014, US , New Technologies and new approaches, 2014.
Tse H.F., Chief Editor, Hong Kong Edition of the Journal of American College of Cardiology, 2014.
Tse H.F., HKU performs the first implant of a newly developed defibrillator in Asia, 2014.
Tse H.F., Invited Speaker, 2014 心血管病治療進展會議, 澳門急性肺梗死旳處理, 2014.
Tse H.F., Invited Speaker, 28th Annual Meeting of the Japanese Heart Rhythm Society, “ Atrial Fibrillation and Stroke. New horizon in anticoagulation”, 2013.
Tse H.F., Invited Speaker, 7th Asia Pacific Cardiology Update USM 2013, Malaysia “ Evaluation for Cardiac Resynchronsastion Device Therapy” & “ Stem Cell Therapy in Heart Failure” , 2013.
Tse H.F., Invited Speaker, APHRS Summit Scientific Programme, Singapore 2014, “An MRI conditional device is needed for all patient”, 2014.
Tse H.F., Invited Speaker, Annual meeting of Taiwan Heart Rhythm Society in Taipei, Taiwan ,”Atrial Fibrillation and Stroke Burden in Asia: From Guideline to Real World Practice”, 2014.
Tse H.F., Invited Speaker, Heart Rhythm 2014, US , Dual-targeted Thoracic Spinal Cord Stimulation for Heart Failure as a Restorative Treatment (SCS Heart):First-in man Experience, 2014.
Tse H.F., Invited Speaker, Macau Association of Cardiovascular Interventions 2013, “ Interpretation of the ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012”, 2013.
Tse H.F., Invited Speaker, Macau Cardiology Association“Cardioprotection of Beta-blockers in Cardiovascular diseases”, 2014.
Tse H.F., Invited Speaker, NOACs Stroke Prevention in Atrial Fibrillation, Malaysia 2014 “NOACs for Stroke Prevention in Atrial Fibrillation- Selecting the Right Treatment for the Right Patient ‘ , “Stroke prevention in AF – Translating Guidelines into Clinical Practice”, 2014.
Tse H.F., Invited Speaker, Pacing Summit, Haizhou, China, “香港起搏植入臨床研究發展與近況", 2014.
Tse H.F., Invited Speaker, The 16th South China International Congress of Cardiology, Guangzhou, China,” Treatment of ventricular tachycardia storm in patients with LMNA A/C related dilated cardiomyopathy, 2014.
Tse H.F., Invited Speaker, The 7th Qianjiang International Cardiovascular Congress, Hangzhou, China, “ Futuristic Cardiac Implantable Electronic Device For Cardiac Rhythm Management” “心衰的神经调节治疗”, 2013.
Tse H.F., Invited Speaker, 利伐沙班SPAF中港專家諮詢會2013, 上海, “新型口服抗凝藥 物的合理應用及出血管理”, 2013.
Tse H.F., Invited Speaker, 協和心臟會議2013, Beijing“香港病例”, 2013.
Tse H.F., Invited Speaker, 拜耳區域心血管專家顧問會, 廣洲, “新型口服抗凝藥 物的合理應用及出血管理”, 2013.
Tse H.F., Member of the Editorial Board, European Heart Journal – Cardiovascular Pharmacotherapy, 2014.
Tse H.F., Member of the Editorial Board, Journal of Cardiovascular Translational Research, 2014.
Tse H.F., Wang Y.J., Ai-abdullah M.A., Pizarro-Borromeo A.B., Chiang C.E., Krittayaphong J., Singh B., Vora A., Wang X., Zubaid M., Clemens A., Lim P. and Hu D., Stroke prevention in atrial fibrillation – An Asian stroke perspective. , Heart Rhythm . 2013, 10: 1082-1088.
Tse W.S., Lau Y.M., Lai W.H., Kung H.W., Tse H.F., Lau G.K.K. and Siu D.C.W., Modelling Friedreich ataxia using patient-specific induced pluripotent stem cells, 9th International Symposium of Healthy Aging, March 2014.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
XIE B., Au Yeung K.M., Tse H.F. and Cheung R.T.F., Aspirin resistance and silent brain infarcts in asymptomatic aspirin users, Asia Pacific Stroke Conference 2013. 36 (supp 1): 94.
YUNG S.Y.J., Tse H.F., Tam P.K.H. and Ngan E.S.W., A patient-specific iPSC model for studying the pathophysiology of Hirschsprung's disease [poster], The 12th Annual Meeting of the International Society for Stem Cell Research, Vancouver, Canada, 18-21 June 2014.
Yiu K.H., Lau G.K.K., Zhao C., Chan Y.H., Chen Y., Zhen Z., Wong A., Lau C.P. and Tse H.F., Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus, Cardiovascular Diabetology. 2014, 13:63: 1-8.
Yiu K.H., Yeung C.K., Zhao C., Chan J.C., Siu D.C.W., Tam S., Wong C.S., Yan G.H., Yue W.S., Khong P.L., Cha H. and Tse H.F., Prevalence and extent of subclinical atherosclerosis in patients with psoriasis, J Intern Med. 2013, 3: 273-282.
Yiu K.H., Wong A., Pu L., Chiang R., Sit K.Y., Chan D., Lee H.Y., Lam Y.M., Chen Y., Siu D.C.W., Lau C.P., Au K.W. and Tse H.F., Prognostic value of preoperative right ventricular geometry and tricuspid valve tethering area in patients undergoing tricuspid annuloplasty, Circulation. 2014, 129: 87-92.
Yiu K.H. and Tse H.F., Specific role of impaired glucose metabolism and diabetes in endothelial progenitor cell characteristics and function., Arterioscler Thromb Vasc Biol. 2014, 34: 1136-1143.
ZHANG J., Ho J.C.Y., Chan Y.C., Lian Q., Siu D.C.W. and Tse H.F., Overexpression of myocardin induces partial transdifferentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells into cardiomyocytes, Physiological Reports. 2014, 2: n/a-n/a.
ZHANG Y., Yue J., CHE H., Sun H., Tse H.F. and Li G.R., BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells., J Cell Physiol. . 2013, 229(2): 202-212.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.
Zuo M., Yue W., Yip T., Ng F., Lam K.F., Yiu K.H., Lui S.L., Tse H.F., Siu D.C.W. and Lo W.K., Prevalence of and Associations With Reduced Exercise Capacity in Peritoneal Dialysis Patients, In: Andrew S. Levey, Daniel E. Weiner, American Journal of Kidney Diseases. Elsevier, 2013, 62: 939-946.


Researcher : Tse HM

List of Research Outputs

Ho W.L., Tse H.M., Liu H., Lu S., Ho W.M., Kung M.H.W., Ramsden D.B. and Ho S.L., Assessment of Cellular Estrogenic Activity Based on Estrogen Receptor-Mediated Reduction of Soluble-Form Catechol-O-Methyltransferase (COMT) Expression in an ELISA-Based System, PLoS ONE. 2013, 8(9): e74065.
Liu H., Lu S., Ho W.L., Tse H.M., Pang S.Y.Y., Kung M.H.W., Ho W.M., Ramsden D.B., Zhou Z. and Ho S.L., LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. , Annals of Clinical and Translational Neurology. 2014, 1(3): 199-208.
Liu H., Ho W.L., Tse H.M., Leung C.T.G., Kung M.H.W., Zhou Z., Ramsden D.B. and Ho S.L., Leucine-rich repeat kinase-2 (LRRK2) R1441G knockin mice are more susceptible to rotenone toxicity , 18th International Congress of Parkinson’s Disease and Movement Disorders, June 2014, sweden.. 2014, 29.


Researcher : Tso AWK

Project Title:A population-based prospective study to investigate the associations of obesity and adipokines with the incidence of cardiovascular disease and cancer
Investigator(s):Tso AWK, Cheung BMY, Lam KSL, Lam TH, Tse HF, Wat NMS
Department:Medicine
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:12/2008


Project Title:Adipocyte fatty acid-binding protein – an adipocytokine with a role in diabetic nephropathy ?
Investigator(s):Tso AWK, Lam KSL, Chan DTM, Xu A
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2009


List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Chow W.S., Yuen M.M.A., Lee P.C.H., Woo Y.C., Tso A.W.K., Xu A., Fong H.Y., Cheung B.M.Y. and Lam K.S.L., Circulation fibroblast growth factor 21 levels predict incident hyperglycaemia in Chinese subject without the metabolic syndrome, IDF World Diabetes Congress, 2-6 Dec 2013, Melbourne, Australia. 2013.
Chow W.S., Xu A., Woo Y.C., Tso A.W.K., Cheung C.W.S., Fong H.Y., Tse H.F., Chau M.T., Cheung B.M.Y. and Lam K.S.L., Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arterioscler Thromb Vasc Biol . 2013, 33: 2454-9.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.


Researcher : Tsoi YYO

List of Research Outputs

Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.
Wong D.K.H., Tsoi Y.Y.O., Huang F.Y., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Application of co-amplification at lower denaturation temperature-PCR (COLD-PCR) sequencing for the early detection of antiviral drug resistance mutations of hepatitis B virus, Journal of Clinical Microbiology. 2014.
Wong D.K.H., LIN S.C., Huang F.Y., Tsoi Y.Y.O., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Association of methylated histones and DNA methylases with hepatitis B virus covalently closed circular DNA and their association with hepatitis B virus replication, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S214.


Researcher : WANG B

List of Research Outputs

Cheng K.Y., Lam K.S.L., WANG B. and Xu A., Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin, Best Pract Res Clin Endocrinol Metab. 2014, 28: 3-13.
Cheng K.Y., Lam K.S.L., WANG B. and Xu A., Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin, Best Practice & Research Clinical Endocrinology & Metabolism. 2013.
Cheng K.Y., Zhu W., CHEN B., Wang Y., Wu D., Sweeney G., WANG B., Lam K.S.L. and Xu A., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle, Diabetes. 2014, DB_140337: Epub ahead of print.
Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].


Researcher : WANG L

List of Research Outputs

WANG L., Kwong Y.L., Wong K.F., Kho C.S.B., Jin D., Tse E.W.C., Rosen A. and Chim J.C.S., Epigenetic inactivation of miR-34b/c in addition to miR-34a and DAPK1 in chronic lymphocytic leukemia, J Transl Med. 2014, 12(1): 52.


Researcher : WONG HK

List of Research Outputs

WONG H.K., Ong K.L., Leung Y.H., Lam T.H., Thomas G.N., Lam K.S.L. and Cheung B.M.Y., A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels, Clinical Endocrinology. 2013, 79(4): 504-9.
WONG H.K., Tang F., Cheung T.T. and Cheung B.M.Y., Adrenomedullin and diabetes., World J Diabetes.. 2014, 5(3): 364-71.
WONG H.K., Leung Y.H. and Cheung B.M.Y., Effects of advanced glycation endprouducts on adrenomedullin gene expression in macrophages, 17th Annual Scientific Meeting Institute of Cardiovasclar Science and Medicine 23 November 2013, Hong Kong. 2013, 21: 69.
WONG H.K., ONG K.L., Cheung C.L. and Cheung B.M.Y., Utilization of glucose, blood pressure, and lipid lowering medications among people with type II diabetes in the United States, 1999-2010., Ann Epidemiol. . 2014, 24(7): 516-21.


Researcher : WONG WLD

List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
Yiu W.H., WONG W.L.D., Leung J.C.K., Chan Y.Y., Lan H.Y., Lai K.N. and Tang S.C.W., Tissue Kallikrein Mediates Pro-Inflammatory Pathways in Proximal Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 315A.
Yiu W.H., WONG W.L.D., Chan Y.Y., Leung J.C.K., Chan K.W., lan H.Y., Lai K.N. and Tang S.C.W., Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells., PLoS One. 2014, 9 (2): e88894.


Researcher : WU H

List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Mok T.M.Y., WU H., Lau C.S. and Chan W.K., Phenotype and function of alternatively activated dendritic cells derived from patients with systemic lupus erythematosus, Annual Scientific meeting of Japan College of Rheumatology 2014, Japan. 2014.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : WU H

List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Mok T.M.Y., WU H., Lau C.S. and Chan W.K., Phenotype and function of alternatively activated dendritic cells derived from patients with systemic lupus erythematosus, Annual Scientific meeting of Japan College of Rheumatology 2014, Japan. 2014.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : WU W

List of Research Outputs

WU W., Wang Y., Deng X.L., Sun H. and Li G.R., Cholesterol Down-Regulates BK Channels Stably Expressed in HEK 293 Cells., PLoS One. 2013, 8(11): e79952.


Researcher : Wang AYM

Project Title:An epidemiologic survey of vitamin D deficiency in Chinese patients with moderate to severe chronic kidney disease
Investigator(s):Wang AYM, Kwan CW, Lai KN
Department:Medicine
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:07/2008


Project Title:Providing intravenous paricalcitol treatment to the sick and poor chronic hemodialysis patients with severe secondary hyperparathyroidism resistant to existing vitamin D analogs
Investigator(s):Wang AYM
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010




Researcher : Wang J

Project Title:Characterization of the interaction between XAF1 and FHL2 in carcinogenesis and differentiation of gastrointestinal cancers
Investigator(s):Wang J, Wong BCY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2008


Project Title:Elucidation of the role of Sp1 in maintaining the survival and renewal of colon cancer stem cells
Investigator(s):Wang J, Wong BCY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2009




Researcher : Wang J.

Project Title:Characterization of the interaction between XAF1 and FHL2 in carcinogenesis and differentiation of gastrointestinal cancers
Investigator(s):Wang J, Wong BCY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2008


Project Title:Elucidation of the role of Sp1 in maintaining the survival and renewal of colon cancer stem cells
Investigator(s):Wang J, Wong BCY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2009




Researcher : Wang Y

List of Research Outputs

WU W., Wang Y., Deng X.L., Sun H. and Li G.R., Cholesterol Down-Regulates BK Channels Stably Expressed in HEK 293 Cells., PLoS One. 2013, 8(11): e79952.
Wang Y., Yeung S.C., Ip M.S.M. and Mak J.C.W., Suppression of inflammation during adipogenic differentiation in human preadipocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Supp 1): P 42 (68).
Ye D., Wang Y., Li H., Jia W., Man K., Lo C.M., Wang Y., Lam K.S.L. and Xu A., Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice, Hepatology. 2014, Epub on 2014-02-06.


Researcher : Wang Y

List of Research Outputs

WU W., Wang Y., Deng X.L., Sun H. and Li G.R., Cholesterol Down-Regulates BK Channels Stably Expressed in HEK 293 Cells., PLoS One. 2013, 8(11): e79952.
Wang Y., Yeung S.C., Ip M.S.M. and Mak J.C.W., Suppression of inflammation during adipogenic differentiation in human preadipocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Supp 1): P 42 (68).
Ye D., Wang Y., Li H., Jia W., Man K., Lo C.M., Wang Y., Lam K.S.L. and Xu A., Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice, Hepatology. 2014, Epub on 2014-02-06.


Researcher : Wat KL

List of Research Outputs

Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.


Researcher : Wat NMS

List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.


Researcher : Wong B.C.Y.

Project Title:Effect of XAF1 gene on tumor growth in gastric and colon cancer
Investigator(s):Wong BCY, Tu S
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2003


Project Title:Role of Bcl-2 family proteins in non-steroidal anti-inflammatory drug-induced apoptosis of gastric cancer
Investigator(s):Wong BCY, Xia HHX
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2004


List of Research Outputs



Researcher : Wong BCY

Project Title:Effect of XAF1 gene on tumor growth in gastric and colon cancer
Investigator(s):Wong BCY, Tu S
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2003


Project Title:Role of Bcl-2 family proteins in non-steroidal anti-inflammatory drug-induced apoptosis of gastric cancer
Investigator(s):Wong BCY, Xia HHX
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2004


List of Research Outputs

Dai Y., Wilson G., Huang B., Peng M., Teng G., Zhang D., Zhang R., Ebert M.P., Chen J., Wong B.C.Y., Chan K.W., George J. and Qiao L., Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer, Cell Death Dis. 2014, 5: e1170.


Researcher : Wong CM

Project Title:The role of beta Klotho in regulation of metabolic homeostasis: Molecular Basis and Physiological Implications
Investigator(s):Wong CM, Xu A
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:04/2012
Completion Date:03/2014


Project Title:Deciphering the role of lipocalin 13 in obesity and diabetes: from molecular analysis to physiological relevance
Investigator(s):Wong CM, Xu A
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:To study the role of mouse G-protein couple receptor GPR110 in the pathogenesis of obesity related medical complication
Investigator(s):Wong CM
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Chan C.P., Kok K.H., Tang V.H.M., Wong C.M. and Jin D., Internal ribosome entry site-mediated translational regulation of ATF4 splice variant in mammalian unfolded protein response, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2013, 1833: 2165-2175.
KONG K.Y., Tang V.H.M., Pan K., HUANG Z., LEE T.H.J., Hinnebusch A., Jin D. and Wong C.M., Cotranscriptional recruitment of yeast TRAMP complex to intronic sequences promotes optimal pre-mRNA splicing, Nucleic Acids Research. Oxford Journals, 2014, 42: 643-660.


Researcher : Wong DKH

Project Title:Mutational analysis of the hepatitis B core protein DNA-binding domain and its role in HBV transcription regulation
Investigator(s):Wong DKH, Huang FY, Lai CL, Yuen RMF
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013


Project Title:Hepatitis B X protein primary structure and epigenetic regulation of HBV replication
Investigator(s):Wong DKH, Huang FY, Seto WKW, Fung JYY, Lai CL, Yuen RMF
Department:Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:03/2014


List of Research Outputs

Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Defining Normal Liver Stiffness Range in a Normal Healthy Chinese Population without Liver Disease, PLoS One. 2013, 8(12): e85067.
Fung J.Y.Y., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Hepatitis B surface antigen levels after hepatitis B e-antigen seroclearance: a longitudinal follow-up study, Liver Int. 2014.
Fung J.Y.Y., Lai C.L., Wong D.K.H., Seto W.K.W., Kopaniszen M. and Yuen R.M.F., Level of hepatitis B surface antigen and not HBV DNA level after HBeAg seroclearance is predictive of HBsAg seroclearance, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S259.
Fung J.Y.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Spontaneous hepatitis B e-antigen seroconversion without subsequent antiviral therapy is associated with higher rates of hepatitis B surface antigen seroclearance, Annual Meeting, American Association for the Study of Liver Disease. 2013.
Huang F.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Estrogen represses anti-apoptotic genes expression via MiR-23a: contribution to sex differences in the development of hepatocellular carcinoma, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 667). Hepatology International. 2014, 8(S1): S243.
Huang F.Y., Wong D.K.H., Seto W.K.W., Zhang A.Y., Lee C.K., Lin C.K., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Sequence Variations of Full-Length Hepatitis B Virus Genomes in Chinese Patients with HBsAg-Negative Hepatitis B Infection, PLoS One. 2014, 9(6): e99028.
Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.
Lam Y.F., Wong D.K.H., Seto W.K.W., To K.K.W., Hung I.F.N., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., HLA-DP and interferon gamma receptor-2 gene variants and their association with viral hepatitis activity in chronic hepatitis B infection., Journal of Gastroenterology and Hepatology. 2014, 29(3): 533-539.
Lin X.F., Shi K.Q., You J., Liu W.Y., Luo Y.W., Wu F.L., Chen Y.P., Wong D.K.H., Yuen R.M.F. and Zheng M.H., Increased risk of colorectal malignant neoplasm in patients with nonalcoholic fatty liver disease: a large study, Molecular Biology Reports. Springer Netherlands, 2014, 41(5): 2989-97.
Seto W.K.W., Lam Y.F., Fung J.Y.Y., Wong D.K.H., Huang F.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after five years of entecavir treatment, J Gastroenterol Hepatol. 2013, 29(5): 1028-34.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing hematopoietic stem cell transplant: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing rituximab-containing chemotherapy: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Liu K.S.H., Lai C.L. and Yuen R.M.F., Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B, Clinical Microbiology and Infection. 2014.
Seto W.K.W., Tanaka Y., Shinkai N., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Performance of a highly sensitive hepatitis B surface antigen assay among chronic hepatitis B patients after hepatitis B surface antigen seroclearance, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014. (Absno. 208). Hepatology International. 2014, 8(S1): S69.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Lai C.L. and Yuen R.M.F., Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy, Hepatology. 2013, 58(3): 923-31.
Seto W.K.W., Tsang O.T., Liu K., Chan J.M., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection, Journal of Viral Hepatitis. 2013, 20(7): 470-7.
Shi K.Q., Wu F.L., Liu W.Y., Zhao C.C., Chen C.X., Xie Y.Y., Wu S.J., Lin X.F., Chen Y.P., Wong D.K.H., Yuen R.M.F. and Zheng M.H., Non-alcoholic fatty liver disease and risk of in-stent restenosis after bare metal stenting in native coronary arteries, Molecular Biology Reports. Springer Netherlands, 2014.
Wong D.K.H., Tsoi Y.Y.O., Huang F.Y., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Application of co-amplification at lower denaturation temperature-PCR (COLD-PCR) sequencing for the early detection of antiviral drug resistance mutations of hepatitis B virus, Journal of Clinical Microbiology. 2014.
Wong D.K.H., LIN S.C., Huang F.Y., Tsoi Y.Y.O., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Association of methylated histones and DNA methylases with hepatitis B virus covalently closed circular DNA and their association with hepatitis B virus replication, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S214.
Wong D.K.H., Kopaniszen M., Omagari K., Tanaka Y., Fong D.Y.T., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Zhang A.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Effect of Hepatitis B Virus Reverse Transcriptase Variations on Entecavir Treatment Response, Journal of Infectious Diseases. 2014.
Wong D.K.H., Fung J.Y.Y., Lee C.K., Seto W.K.W., Leung J., Huang D.K.H., Lin C.K., Lai C.L. and Yuen R.M.F., Hepatitis B virus serological and virological activities in blood donors with occult hepatitis B, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 868). Hepatology International. 2014, 8(S1): S149.
Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.
ZHANG A., Wong D.K.H., Huang F.Y., Fung J.Y.Y., Seto W.K.W., Poon R.T.P., Lai C.L. and Yuen R.M.F., Characterization of intrahepatic HBV quasispecies genetic variability within the pre-S region in patients with HBV-related hepatocellular carcinoma, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Zheng M.H., Seto W.K.W., Shi K.Q., Wong D.K.H., Fung J.Y.Y., Hung I.F.N., Fong D.Y.T., Yuen J.C.H., Tong T., Lai C.L. and Yuen R.M.F., Artificial neural network accurately predicts hepatitis B surface antigen seroclearance, PLoS One. 2014, 9(6): e99422.


Researcher : Wong HYH

List of Research Outputs

Chiu J.W.Y., Tang Y.F., Leung R.C.Y., Wong H.Y.H., Chu K.W., Poon T.C.J., Epstein R. and Yau T.C.C., Efficacy and Tolerability of Adjuvant Oral Capecitabine plus Intravenous Oxaliplatin (XELOX) in Asian patients with Colorectal Cancer: 4-Year Analysis, Asia Pacific Journal of Cancer Prevention. 2013, 14: 6585-6590.
Yau T.C.C., Leung R.C.Y., Wong H.Y.H., Chiu J.W.Y., Chan P., Tang Y.F., Cheung T.T., Pang R.W.C., Fan S.T. and Poon R.T.P., Efficacy and safety of single agent sunitinib in treating sorafenib refractory advanced hepatocellular carcinoma patients: a prospective, open-label, phase II study, The 4th Asia-Pacific Primary Liver Cancer Expert Meeting, Busan, Korea, 5-7 July 2013.


Researcher : Wong KY

Project Title:Epigenetic regulation of tumour suppressor miR-33b in multiple myeloma
Investigator(s):Wong KY, Chim JCS
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:04/2013


List of Research Outputs

Wang L.Q., Kwong Y.L., Kho C.S., Wong K.F., Wong K.Y., Ferracin M., Calin G.A. and Chim J.C.S., Epigenetic inactivation of miR-9 family microRNAs in chronic lymphocytic leukemia - implications on constitutive activation of NFkappaB pathway, Mol Cancer.. 2013, 12: 173.
Wong K.Y., Wan T.S.K., So J.C.C. and Chim J.C.S., Establishment of a Chinese human multiple myeloma cell line: MMLAL, Cancer Cell Int. . 2013, 13(1): 122.


Researcher : Wong LC

List of Research Outputs

Shea Y.F., Chu L.W., Zhou L., Li W.M., Lin O.Y., Chan M.N.Y., Xu A., Wong L.C., Ho T.Y. and Liu K.W., Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Chinese Patients: A Pilot Study, American Journal of Alzheimer's Disease and Other Dementias. 2013, 28: 769-775.


Researcher : Wong LYF

Project Title:Involvement of NF-κB and cAMP-dependent protein kinase pathways in adrenomedullin-induced cytokine responses in macrophages
Investigator(s):Wong LYF, Cheung BMY
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Mechanism of the modulation of cytokine responses by adrenomedullin and adrenomedullin binding protein-1 in macrophages: a novel pathway in sepsis with therapeutic implications
Investigator(s):Wong LYF, Cheung BMY
Department:Medicine
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:10/2006




Researcher : Wong RWS

List of Research Outputs

Lau W.C.S., Au Y.L., Chan Y.Y., Chan Y.T., Chan O.W., Cheung T.T., Chung H.Y., Ho C.T.K., Kowk S.K., Lee W.S., Li W.L., Lui M.S., Mok T.M.Y., Tang L.M., Tsang H.L., Yuen K.Y.C. and Wong R.W.S., Outstanding Team 2014, Hong Kong West Cluster cum Queen Mary Hospital. 2014.
Mok C.C., Tam L.S., Leung M.H., Ying K.Y., To C.H., Lee K.L., Ho L.Y., Yip M.L., Tsui H.S., Chan T.H., Lee K.W., Li E.K., Hong Kong Society of Rheumatology , Chan E.Y., Chan K.H., Chan K.M., Chan K.Y., Chan P.S., Chan Y.K., Chau S.Y., Cheung T.C., Cheung T.T., Chung H.Y., Ho C.T.K., Kun E., Kwok L.W., Kwok M.L., Kwok K., Lam C.K., Lao W.N., Lau W.C.S., Lau Y.L., Lee A.K., Lee T.K., Lee K.K., Lee M.Y., Lee S.S., Lee T.L., Yan T., Leung M.C., Li W.L., Liu H.M., Luk M.C., Ma K.Y., Mak L.W., Mok T.M.Y., Ng K.H., Ng W.L., So H., Sung C.K., Tan R.F., Tang S.K., Wan M.C., Wong C.H., Wong K.C., Man S., Wong P.Y., Wong J., Wong R.W.S., Woo W.S., Young K.Y., Yim C.W., Yu K.L., Yuen K.Y.C. and Yung K.M., Referral strategy for early recognition of axial spondyloarthritis: consensus recommendations from the Hong Kong Society of Rheumatology., Int J Rheum Dis. 2013, 16(5): 500-8.
ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.


Researcher : Wong SY

List of Research Outputs

Leung W.K., Lo O.S.H., Liu K.S., Tong S.M., But Y.K.D., Lam F.Y., Hsu A.S.J., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., Detection of Colorectal Adenoma by Narrow Band Imaging (HQ190) vs. High-Definition White Light Colonoscopy: A Randomized Controlled Trial, Am J Gastroenterol. 2014, 109(6): 855-63.
Liu K.S., Hung I.F.N., Seto W.K.W., Tong S.M., Hsu A.S.J., Lam F.Y., But Y.K.D., Wong S.Y. and Leung W.K., Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial, Gut. 2013.
Lo O.S.H., Liu K.S.H., Tong S.M., Wong S.Y., Seto W.K.W., Hung I.F.N. and Law W.L., New High Definition Narrow Band Imaging vs Conventional White Light Colonoscopy for Detection of Colorectal Adenomas in Symptomatic Patients: A Randomized Controlled Trial with Tandem Colonoscopy, United European Gastroenterology Week, 12-16 Oct 2013, Berlin, Germany. 2013.


Researcher : Wong Y

List of Research Outputs

Shiu S.W.M., Xiao S., Wong Y., Chow W.S., Lam K.S.L. and Tan K.C.B., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clinical Science. Great Britain, 2014, 126: 175-181.
TSUN G.S., Shiu S.W.M., Wong Y., Yung S.S.Y., Chan D.T.M. and Tan K.C.B., Impact of serum amyloid A on cellular cholesterol efflux to serum in type 2 diabetes mellitus., Atherosclerosis.. 2013, 231: 405-10.
Tan K.C.B., Lee A.C., Lam J.K., Shiu S.W.M. and Wong Y., Association between Soluble Receptor for Advanced Glycation End Products and A Disintegrin And Metalloproteinase 10 in Type 1 Diabetes., 16th International Congress of Endocrinology and the Endocrine Society's 96th Annual Meeting in Chicago, USA.. 2014.


Researcher : Wong YK

List of Research Outputs

Lau G.K.K., Wong Y.K., Chan K.H., Teo K.C., Hon S.F.K., Mak W., Cheung R.T.F., Ho S.L., Li L.S.W., Tse H.F. and Siu D.C.W., Cancer patients are at increased risk of recurrent stroke and cardiovascular mortality, Journal of the Neurological Sciences. 2013, 333, e204.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Wong Y.K., Teo K.C., Chang S.K.R., Chan K.H., Hon F.K.S., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W. and Tse H.F., Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke, American Journal of Hypertension [Epub ahead of print]. 2014.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Chan K.H., Li O.Y., Tong S., Wong D., Shu X.O., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Mediterranean-style diet reduces blood pressure variability and subsequent stroke risk in patients with coronary artery disease , 9th International Symposium of Healthy Aging, March 2014.
Lau G.K.K., Wong Y.K., Teo K.C., Chang R.S.K., Hon S.F.K., Chan K.H., Cheung R.T.F., Li L.S.W., Tse H.F., Ho S.L. and Siu D.C.W., Stroke Patients with a Past History of Cancer Are at Increased Risk of Recurrent Stroke and Cardiovascular Mortality, PLoS One. 2014, 9(2): e88283.
Lau G.K.K., Wong Y.K., Chan Y.H., Teo K.C., Chan K.H., Li L.S.W., Cheung R.T.F., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases – Relationships and comparisons with vascular markers of atherosclerosis, Atherosclerosis. 2014, 235(1): 230-235.
Lau G.K.K., Wong Y.K., Chang R.S., Teo K.C., Hon S.F., Chan K.H., Wat K.L., Cheung R.T., Li L.S., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 14th Asian & Oceanian Congress of Neurology, Macao, China. 2014.
Lau G.K.K., Wong Y.K., Chang S.K.R., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, 66th American Academy of Neurology Annual Meeting, Philadelphia, USA, April 26 - May 3, 2014.
Lau G.K.K., Wong Y.K., Chang R.S.K., Teo K.C., Hon S.F.K., Chan K.H., Wat K.L., Cheung R.T.F., Li L.S.W., Siu D.C.W., Ho S.L. and Tse H.F., Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct, European Journal of Neurology. 2014, 21(2): 319-325.


Researcher : Woo YC

List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Chow W.S., Yuen M.M.A., Lee P.C.H., Woo Y.C., Tso A.W.K., Xu A., Fong H.Y., Cheung B.M.Y. and Lam K.S.L., Circulation fibroblast growth factor 21 levels predict incident hyperglycaemia in Chinese subject without the metabolic syndrome, IDF World Diabetes Congress, 2-6 Dec 2013, Melbourne, Australia. 2013.
Chow W.S., Xu A., Woo Y.C., Tso A.W.K., Cheung C.W.S., Fong H.Y., Tse H.F., Chau M.T., Cheung B.M.Y. and Lam K.S.L., Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arterioscler Thromb Vasc Biol . 2013, 33: 2454-9.
Lam K.S.L., Hui Y.L.E., Yuen M.A.M., Yeung C.Y., Woo Y.C., Fong H.Y. and Xu A., Circulating fibroblast growth factor 21 level predicts the progression of diabetes nephropathy in patients with type 2 diabetes, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo, 17-24 Jun 2014, Chicago, USA.. 2014.
Loong C.H., Woo Y.C., Hui Y.L.E., Leung E.L., Yee S.W., Lam K.S.L. and Tan K.C.B., Advanced osteoporosis triage system shortens the waiting time for osteoporosis clinic., Health Authority Convention in Hong Kong.. 2014.
Loong C.H., Woo Y.C., Hui Y.L.E. and Tan K.C.B., Simple risk assessment tools to identify post-menopausal women with fracture risk in community., 15th Regional Osteoporosis Conference.. 2014.
Woo Y.C., Loong N.H.C., Hui Y.L.E., Leung E., Kung A.W.C. and Tan K.C.B., History- an physical examination-based model showed good discrimination ability in fracture prediction., World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Disease in Seville.. 2014.
Yeung C.Y., Hui Y.L.E., Lam T.H., Chow W.S., Woo Y.C., Fong H.Y., Xu A., Cheung B.M.Y. and Lam K.S.L., Plasma fibrinogen level as a predictor of incident metabolic syndrome in a community-based prospective study in Hong Kong Chinese, European Association for the Study of Diabetes. 2013.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.


Researcher : Wu CH

List of Research Outputs

Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.


Researcher : Wu H

List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Mok T.M.Y., WU H., Lau C.S. and Chan W.K., Phenotype and function of alternatively activated dendritic cells derived from patients with systemic lupus erythematosus, Annual Scientific meeting of Japan College of Rheumatology 2014, Japan. 2014.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : XIE B

List of Research Outputs

XIE B., Au Yeung K.M., Tse H.F. and Cheung R.T.F., Aspirin resistance and silent brain infarcts in asymptomatic aspirin users, Asia Pacific Stroke Conference 2013. 36 (supp 1): 94.
XIE B., ZHANG M., Mak H.K.F. and Cheung R.T.F., Blood pressure variability, silent cerebrovascular lesions and cognitive impairment in healthy hypertensive elderly Chinese, 18th Research Postgraduate Symposium. 2013, 3.18.
XIE B., ZHANG M., Mak H.K.F. and Cheung R.T.F., Visit-to-visit blood pressure variability is associated with periventricular white matter hyperintensity in healthy hypertensive elderly Chinese, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 46.
ZHANG M., XIE B., Mak H.K.F. and Cheung R.T.F., Absence of association between arterial stiffness and white matter hyperintensities in otherwise healthy hypertensive elderly Chinese, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 51.
ZHANG M., XIE B., Mak H.K.F. and Cheung R.T.F., Arterial stiffness and white matter hyperintensities in healthy hypertensive elderly Chinese, 18th Research Postgraduate Symposium. 2013, 5.26.


Researcher : Xia HHX

Project Title:Homeobox genes in gastric carcinogenesis: an in vivo and in vitro study
Investigator(s):Xia HHX, Wong BCY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2003


Project Title:Role of cyclooxygenase in helicobacter pylori-induced gastric carcinogenesis
Investigator(s):Xia HHX, Wong BCY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2004


Project Title:Role of macrophage migration inhibitory factor in Helicobacter pylori-induced gastric carcinogenesis
Investigator(s):Xia HHX, Wong BCY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2005




Researcher : Xiao S

List of Research Outputs

Shiu S.W.M., Xiao S., Wang Y., Chow W.S., Lam K.S.L. and Cheung B.M.Y., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clin Sci (Lond). 2014, 126: 175-81.
Shiu S.W.M., Xiao S., Wong Y., Chow W.S., Lam K.S.L. and Tan K.C.B., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clinical Science. Great Britain, 2014, 126: 175-181.


Researcher : Xiong J

Project Title:2008 NCRI Cancer Conference Growth inhibitory effect of 5-aza-2'-deoxycytidine on cancer cells is independent of p16 ink4a and p14ARF
Investigator(s):Xiong J
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2008




Researcher : Xu A

Project Title:Molecular mechanism underlaying the pathogenesis of type 2 diabetes
Investigator(s):Xu A
Department:Medicine
Source(s) of Funding:Matching Fund for National Key Basic Research Development Scheme (973 Projects)
Start Date:05/2007


Project Title:APPL2 as a Negative Regulator of Insulin Sensitivity and Glucose Uptake in Skeletal Muscle: A Novel Pathway Leading to Insulin Resistance?
Investigator(s):Xu A
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2011
Completion Date:12/2013


Project Title:Genetic and pathogenic pathways leading to type 2 diabetes Mellitus
Investigator(s):Xu A
Department:Medicine
Source(s) of Funding:Matching Fund for National Key Basic Research Development Scheme (973 Projects)
Start Date:05/2011


Project Title:71th Scientific Sessions of the American Diabetes Association Genetic Inactivation of Toll-Like Receptor 4 Alleviates Diet-Induced Nonalcoholic Steatohepatitis by Inhibiting Reactive Oxygen Species-Evoked Activation of X-box Binding Protein-1 in ApoE-Deficient Mice
Investigator(s):Xu A
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2011


Project Title:A Multi-disciplinary Approach to Investigate Vascular Dysfunction in Obesity and Diabetes: From Molecular Mechanism to Therapeutic Intervention
Investigator(s):Xu A, Vanhoutte PMGR, Wang Y, Lam KSL
Department:Medicine
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2011


Project Title:The Liver-derived Hormone FGF21 as a Novel Regulator of Vascular Function: Molecular Basis and Physiological Implications
Investigator(s):Xu A, Vanhoutte PMGR
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:The adaptor protein APPL1 as a physiological regulator of insulin secretion in pancreatic ?cells
Investigator(s):Xu A, Cheng KY
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:CPT1a as a novel mediator of diabetes-induced oxidative stress and endothelial dysfunction: Mechanisms and physiological implications
Investigator(s):Xu A, Cheng KY
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013
Completion Date:05/2014


Project Title:Physical exercise promotes vascular health: impact of mechano-transduction and novel endothelium-derived regulators
Investigator(s):Xu A
Department:Medicine
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2013


Project Title:Fibroblast growth factor 21 maintains glucose homeostasis during fasting by mediating the crosstalk between liver and brain
Investigator(s):Xu A, Cheng KY
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Adipocyte fatty acid binding protein as a mediator of obesity-related medical complications
Investigator(s):Xu A, Hoo RLC
Department:Medicine
Source(s) of Funding:Germany/Hong Kong Joint Research Scheme
Start Date:01/2014


Project Title:American Diabetes Association 74th Scientific Sessions (2014); Fibroblast Growth Factor 21 and Cardiovascular Outcome Events in the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study
Investigator(s):Xu A
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2014


Project Title:Targetting Neutrophil Serine Proteases for Management of Autoimmune Diabetes
Investigator(s):Xu A, Lam KSL
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2014


Project Title:FGF21 resistance in obese adipose tissues as a mediator of systemic insulin resistance: molecular mechanisms and clinical significance
Investigator(s):Xu A, Hui X
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

BARETELLA O.M., Xu A. and Vanhoutte P.M.G.R., Acidosis prevents and alkalosis augments endothelium-dependent contractions in mouse arteries, Pflugers Archiv : European journal of physiology. . 2013, Epub [2013 Jul 20].
BARETELLA O.M., Chung S.K., Barton M., Xu A. and Vanhoutte P.M.G.R., Obesity and heterozygous endothelial overexpression of prepro-endothelin-1 modulate responsiveness of mouse main and segmental renal arteries to vasoconstrictor agents., Life Sci. . 2014, Epub ahead of print.
Bai B., Liang Y., Xu C., Lee Y.K.M., Xu A., Wu D.H., Vanhoutte P.M.G.R. and Wang Y., CDK5-mediated hyperphosphorylation contributes to the lossof-SIRT1 function during the development of endothelial senescence, International Academy of Cardiology: 18th World congress on Heart Disease, Vancouver, Canada, July 26-29, 2013.
Baretella O.M., Xu A. and Vanhoutte P.M.G.R., Contractions to endogenous and exogenous endothelin-1 in segmental renal arteries of the mouse: up-regulation in obesity, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Heterozygous Endothelial Endothelin-1 Overexpression Potentiates Endothelium-Dependent Contractions in the Carotid Arteries of Obese Mice, HBPR 2013, September 11-14, 2013, New Orleans, LA. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Heterozygous overexpression of preproendothelin-1 in endothelial cells enhances thromboxane-prostanoid receptor-induced contractions in the renal artery of obese mice, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Improved relaxations to acetylcholine in murine carotid arteries with heterozygous overexpression of preproendothelin-1 in the endothelium, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
CHEN J., Xu A., Lam K.S.L., Liu J. and Wang Y., Adiponectin deficiency promotes the development of metaplastic breast cancer-focusing on dysregulated T-cell function, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.
Chatzigeorgiou A., Seijkens T., Zarzycka B., Engel D., Poggi M., van den Berg S., Xu A., Nicolaes G., Chavakis T. and Lutgens E., Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance, Proc Natl Acad Sci USA.. 2014, [Epub ahead of print].
Cheng K.Y., Lam K.S.L., WANG B. and Xu A., Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin, Best Pract Res Clin Endocrinol Metab. 2014, 28: 3-13.
Cheng K.Y., Lam K.S.L., WANG B. and Xu A., Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin, Best Practice & Research Clinical Endocrinology & Metabolism. 2013.
Cheng K.Y., Zhu W., CHEN B., Wang Y., Wu D., Sweeney G., WANG B., Lam K.S.L. and Xu A., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle, Diabetes. 2014, DB_140337: Epub ahead of print.
Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
Cheng O.Y., Lam K.S.L., Chung S.K., Xu A., Yeung P.K.K., Kwan S.C., Ho W.L., Cheng K.Y., Guo Y. and Chan K.H., Cognitive impairment in adiponectin-knockout mice, 19th Medical Research Conference, Department of Medicine, The University of Hong Kong,. Hong Kong, Hong Kong Medicine Journal, 2014, 20 Number 1 (Suppl 1): 14.
Cheng Q., Ng K.T.P., Xu A., Li C., Liu X., Guo D., Poon R.T.P., Fan S.T., Lo C.M. and Man K., The Roles of Lipocalin-2 in Small-for-Size Fatty Liver Graft Injury, Ann Surg. 2013, Epub ahead of print.
Cheng Q., Ng K.T.P., Xu A., Li C., Liu X., Guo D.Y., Poon R.T.P., Fan S.T., Lo C.M. and Man K., The roles of lipocalin-2 in small-for-size fatty liver graft injury, Annals of Surgery. 2013, Epub on 2013-12-26.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Chow W.S., Yuen M.M.A., Lee P.C.H., Woo Y.C., Tso A.W.K., Xu A., Fong H.Y., Cheung B.M.Y. and Lam K.S.L., Circulation fibroblast growth factor 21 levels predict incident hyperglycaemia in Chinese subject without the metabolic syndrome, IDF World Diabetes Congress, 2-6 Dec 2013, Melbourne, Australia. 2013.
Chow W.S., Xu A., Woo Y.C., Tso A.W.K., Cheung C.W.S., Fong H.Y., Tse H.F., Chau M.T., Cheung B.M.Y. and Lam K.S.L., Serum fibroblast growth factor-21 levels are associated with carotid atherosclerosis independent of established cardiovascular risk factors, Arterioscler Thromb Vasc Biol . 2013, 33: 2454-9.
DETREMMERIE C.M.S., Leung S.W.S., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., The endothelium-dependent, soluble guanylyl cyclase-dependent augmentation caused by thymoquinone in isolated porcine coronary arteries is mediated by cIMP, Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
DETREMMERIE C.M.S., Leung S.W.S., Xu A., Alkharfy K. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation depending on activation of soluble guanylyl cyclase in isolated arteries, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.
Deng H., Huang B., Lee I.K., Park S. and Xu A., Clusterin facilitates production and secretion of high molecular weight adponectin, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
Heilbronn L.K., Campbell L.V., Xu A. and Samocha-Bonet D., Metabolically protective cytokines adiponectin and fibroblast growth factor-21 are increased by acute overfeeding in healthy humans., PLoS One. 2013, 8: e78864.
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte Fatty Acid Binding Protein Potentiates Toxic Lipids-induced Endoplasmic Reticulum Stress Via Inhibition Of JAK2-Dependent Autophagy , 12th International Congress on Obesity (ICO) . 2014.
Hoo R.L.C., SHU L., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein (A-FABP) potentiates toxic lipids-induced endoplasmic reticulum stress via suppression of JAK2-dependent autophagy, 19th Medical Research Conference. 2014.
Hoo R.L.C., SHU L., Cheng K.Y., Lam K.S.L. and Xu A., Adipocyte fatty acid binding protein potentiates palmitic acid induced endoplasmic reticulum stress in macrophages via inhibition of Janus kinase 2-dependent autophagy, Singapore Diabetes Forum 2014 . 2014.
Hoo R.L.C., Xu A. and Lam K.S.L., Adipocyte fatty acid binding proten in the pathogenesis of obesity-related nonalcoholic steatohepatitis, Asia-Pacific Diabetes & Obesity Study Group Symposium, 12-13 Oct 2013, Tokyo, Japan. 2013.
Hoo R.L.C., LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and translational (Oral Presentation), 19th Medical Research Conference. 2014.
Hui X., Gu P., Lam K.S.L. and Xu A., SIRT1 antagonizes obesity-induced vascular dysfunction via its actions in PVAT, 14th International Conference of Obesity. 2014.
Hui X., Gu P., Lam K.S.L., Vanhoutte P.M.G.R. and Xu A., SIRT1 modulates white/brown switch in PVAT, 8th Singapore Diabetes Forum. 2014.
Hui Y.L.E., Xu A., Yang H.B. and Lam K.S.L., Obesity as the common soil of non-alcoholic fatty liver disease and diabetes: Role of adipokines., J Diabetes Investig. . 2013, 4: 413-425.
Jüllig M., Yip S., Xu A., Smith G., Middleditch M., Booth M., Babor R., Beban G. and Murphy R., Lower fetuin-a, retinol binding protein 4 and several metabolites after gastric bypass compared to sleeve gastrectomy in patients with type 2 diabetes., PLoS One. 2014, 9: e96489.
LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and Translational (Oral Presentation), 19th Medical Research Conference. 2014.
LI H., LIU Z., Xu A., Cheung C.W., Wong G.T.C., Irwin M.G. and Xia Z., Ischemia postconditioning attenuates myocardial ischemia-reperfusion injury by up-regulating cardiac adeponectin expression in mice, J Diabetes Metab. 2013, 4(6):: 109.
LI T., Yan C.H., Xu A., Song Y. and Chiu P.K.Y., Assessment Of Systemic Inflammation In Oa Patients By Testing Fatty-acid-binding Protein 4 And Adiponectin In Plasma, The 33rd Hong Kong Orthopaedic Association Annual Congress. 2013, 21.
LI T., Yan C.H., Xu A., Song Y. and Chiu P.K.Y., Comparison Of Fatty-acid-binding Protein 4 And Adiponectin Levels In Infrapatellar Fat Pad And Subcutaneous Adipose Tissue, Synovial Fluid And Plasma In Subjects With Knee Osteoarthritis, 33rd Hong Kong Orthopaedic Association Annual Congress. 2013, 21.
Lam K.S.L., Hui Y.L.E., Yuen M.A.M., Yeung C.Y., Woo Y.C., Fong H.Y. and Xu A., Circulating fibroblast growth factor 21 level predicts the progression of diabetes nephropathy in patients with type 2 diabetes, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo, 17-24 Jun 2014, Chicago, USA.. 2014.
Leung S.W.S., DETREMMERIE C.M.S., LI Z., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation of contraction depending on activation of soluble guanylyl cyclase in isolated arteries, 11th International Symposium on Mechanisms of Vasodilatation, 3 to 7 Oct 2013, Zurich, Switzerland. 2013.
Li H., Wei S., Cheng K.Y., Gounko N.V., Ericksen R.E., Xu A., Hong W. and Han W., BIG3 inhibits insulin granule biogenesis and insulin secretion., EMBO Rep. 2014, [Epub ahead].
Li H., Hui X., Yang S., Hu X., Tang X., Li P., Li S., Yang L., Jin S., Wang Y., Xu A. and Wu D., High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pichia pastoris, Protein Expr Purif. 2013, 91: 221-227.
Lin Z., Wu F., Lin S., Pan X., Jin L., Lu T., Shi L., Wang Y., Xu A. and Li X., Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice. , Journal of Hepatology. 2014, Epub ahead of print.
Lin Z., Wu F., Lin S., Pan X., Jin L., Lu T., Wang Y., Xu A. and Li X., Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice, J Hepatol.. 2014, pii: S0168-8278: [Epub ahead of print].
Liu J., Xu A., Lam K.S.L., Wong N.S., CHEN J., Shepherd P.R. and Wang Y., Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation, Oncotarget . 2013, 4: 1804-18.
Liu L., Liu J., Tian X.Y., Wong W.T., Lau C.W., Xu A., Xu G., Ng C.F., Yao X., Gao Y. and Huang Y., Uncoupling Protein-2 Mediates DPP-4 Inhibitor-Induced Restoration of Endothelial Function in Hypertension through Reducing Oxidative Stress., Antioxid Redox Signal. 2013, Epub ahead of print.
Park M., Wu D., Park T., Choi C., Li R., Cheng K.Y., Xu A. and Sweeney G., Appl1 transgenic mice are protected from high fat diet induced cardiac dysfunction, Am J Physiol Endocrinol Metab. 2013, Epub [2013 Aug 6].
Qiu B., Shi X., Wong E.T., Lim J., Bezzi M., Low D., Zhou Q., Akıncılar S.C., Lakshmanan M., Swa H.L., Tham J.M., Gunaratne J., Cheng K.Y., Hong W., Lam K.S.L., Ikawa M., Guccione E., Xu A., Han W. and Tergaonkar V., NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling., Cell Rep.. 2014, 7: 1876-1886.
SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
SONG E., Fan P., Huang B., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice, J Am Heart Assoc.. 2014, 3: e000837.
SONG E., FAN P., Xu A., Feletou M., Vilaine J.P., Vanhoutte P.M.G.R. and Wang Y., Elevated 20-HETE contributes to the improved endothelial function in llpocalin-2 deficient mice, The 12th Meeting of the Asia Pacific Federation of Pharmacologists, Shanghai China, July 9-13, 2013.
Shea Y.F., Chu L.W., Zhou L., Li W.M., Lin O.Y., Chan M.N.Y., Xu A., Wong L.C., Ho T.Y. and Liu K.W., Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Chinese Patients: A Pilot Study, American Journal of Alzheimer's Disease and Other Dementias. 2013, 28: 769-775.
Shen K., Leung S.W.S., Huang Y., Hou M., Xu A., Wang Z. and Vanhoutte P.M.G.R., Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries, Biochem Pharmacol. 2014, Epub ahead of print.
So W.Y., Cheng Q., Chen L., Evans-Molina C., Xu A., Lam K.S.L. and Leung P.S., High glucose represses beta-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: Involvement of peroxisome proliferator-activated receptor gamma signaling, Diabetes. 2013, Epub [2013 Jul 29].
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.
Wu J., Li H., Zhou M., Fang Q., Bao Y., Xu A. and Jia W., Mechanism and clinical evidence of lipocalin-2 and adipocyte fatty acid-binding protein linking obesity and atherosclerosis, Diabetes Metab Res Rev. 2013, Epub ahead of print.
Xu A., Deputy Chair, Biochemical Journal. 2013.
Xu A., FGF21 as a novel metabolic regulator: from bench to bed, 2014中国糖尿病转化医学论坛, 厦门, 2014.
Xu A., FGF21 resistance in adipose tissues as a cause of insulin resistance?, 2013 International Conference on Diabetes and Metabolism & 5th Asian Association for the Study of Diabetes. 2013.
Xu A., FGF21 resistance in adipose tissues as a mediator of systemic insulin resistance, The 7th Asia-Pacific Organization for Cell Biology Congress and American Society for Cell Biology Workshops . 2014.
Xu A., Interplay between adipokines and hepatokines in obesity-related metabolic complications, The 12th International Congress of Obesity, Kuala Lumpur, Malaysia. 2014.
Xu A., The FGF21-adiponectin axis in adipose tissues as a target for obesity-related metabolic disorders, The 5th National Forum on New Technologies in Drug Discovery, Shanghai. 2014.
Xu A., The Metabolic Actions of FGF21 in Adipocytes: Molecular Mechanisms and Therapeutic Implications, 5th Singapore Symposium on Metabolic Diseases. 2013.
Xu A., The Metabolic Hormone FGF21 in Regulating Glucose Homeostasis: Friend or Foe?, 16th Asia-Pacific International Molecular Biology Network (A-IMBN) Annual Conference 2013, Singapore. 2013.
Xu A., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal Muscle, 2014 Asia Obesity and Diabetes Symposium, Osaka, Japan. 2014.
Xu A., The hypothalamic APPL2 as a novel regulator of energy homeostasis, 2014 Seoul International Congress of Endocrinology and Metabolism. 2014.
Xu C., Fan P., Xu A., Vanhoutte P.M.G.R. and Wang Y., Biotin deficiency mimics the beneficial effects of calorie restriction by regulating SIRT1 and acetyl-coA carboxylase 2 in the adipose tissues, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
Yang S., Kuang Y., Li H., Liu Y., Hui X., Li P., Jiang Z., Zhou Y., Wang Y., Xu A., Li S., Liu P. and Wu D., Enhanced production of recombinant secretory proteins in Pichia pastoris by optimizing Kex2 P1' site., Plos One. 2013, 8: e75347.
Yau S.Y., LI A., Zhang E., Christie B.R., Xu A., Lee T.M.C. and So K.F., Sustained Running in Rats Adminstered Corticosterone Prevents the Development of Depressive Behaviors and Enhances Hoppocampal Neurogenesis and Synaptic Plasticity Without Increasing Neurotrophic Factor Levels. Cell Transplantation, 2014, 23: 481-492.
Yau S.Y., Li A., Zhang E., Christie B.R., Xu A., Lee T.M.C. and So K.F., Sustained running in rats administered corticosterone prevents the development of depressive behaviors and enhances hippocampal neurogenesis and synaptic plasticity without increasing neurotrophic factor levels, Cell Transplantaton. 2014, 23: 481-492.
Ye D., Wang Y., Li H., Jia W., Man K., Lo C.M., Wang Y., Lam K.S.L. and Xu A., Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice, Hepatology. 2014, Epub on 2014-02-06.
Yeung C.Y., Hui Y.L.E., Lam T.H., Chow W.S., Woo Y.C., Fong H.Y., Xu A., Cheung B.M.Y. and Lam K.S.L., Plasma fibrinogen level as a predictor of incident metabolic syndrome in a community-based prospective study in Hong Kong Chinese, European Association for the Study of Diabetes. 2013.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.
Zhou M., PAN Y., SHU L., Lam K.S.L., Xu A. and Hoo R.L.C., Adipocyte fatty acid binding protein (A-FABP) is a potential mediator of diabetic cardiomyopathy and ischemic reperfusion induced cardiac injury , Ninth International Symposium on Healthy Aging “Aging with Confidence” . 2014.


Researcher : YAN S

List of Research Outputs

Chan V.S.F., Yan S., TAM C.Y., Shen N. and Lau W.C.S., MicroRNA modulations in plasmacytoid dendritic cells hyperactivity in systemic lupus erythematosus, The 15th International Congress of Immunology 2013, Milan, Italy. 2013.
YAN S., YIM L.Y., Lu L., Lau W.C.S. and Chan V.S.F., MicroRNA Regulation in Systemic Lupus Erythematosus Pathogenesis., Immune Netw. 2014, 14(3): 138-48.


Researcher : YIM LY

List of Research Outputs

YAN S., YIM L.Y., Lu L., Lau W.C.S. and Chan V.S.F., MicroRNA Regulation in Systemic Lupus Erythematosus Pathogenesis., Immune Netw. 2014, 14(3): 138-48.


Researcher : Yan S

List of Research Outputs

Chan V.S.F., Yan S., TAM C.Y., Shen N. and Lau W.C.S., MicroRNA modulations in plasmacytoid dendritic cells hyperactivity in systemic lupus erythematosus, The 15th International Congress of Immunology 2013, Milan, Italy. 2013.
YAN S., YIM L.Y., Lu L., Lau W.C.S. and Chan V.S.F., MicroRNA Regulation in Systemic Lupus Erythematosus Pathogenesis., Immune Netw. 2014, 14(3): 138-48.


Researcher : Yap YHD

Project Title:American Society of Nephrology Kidney Week 2012; Outcome of long-term treatment with mycophenolate mofetil in patients with severe lupus nephritis
Investigator(s):Yap YHD
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2012


Project Title:The effect of activated T lymphocytes on cytokine secretion in renal proximal tubular epithelial cells - implications in lupus nephritis
Investigator(s):Yap YHD, Yung SSY, Chan DTM
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2013
Completion Date:01/2014


Project Title:A Therapeutic Drug Monitoring Program of Mycophenolic Acid in patients with Lupus Nephrities
Investigator(s):Yap YHD
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:12/2013


List of Research Outputs

Chan C.Y.J., Yap Y.H.D. and Yeung C.K., Hydralazine-induced toxic epidermal necrolysis in a patient on continuous ambulatory peritoneal dialysis, Journal of Clinical Pharmacy and Therapeutics. 2014, 39: 322-324.
Chan K.Y., Cheng H.W., Yap Y.H.D., Yip T., Li C.W., Sham M.K., Wong P.C. and Lau W.K., Reduction of Acute Hospital Admissions and Improvement in Outpatient Attendance by Intensified Renal Palliative Care Clinic Follow-Up: The Hong Kong Experience., Journal of Pain Symptom Management. 2014.
Ma K.M.M., Zuo M.L., Yap Y.H.D., Mok M.M., Kwan L.P., Chan G.C., Siu D.C.W. and Chan D.T.M., Chronotropic incompetence, echocardiographic abnormalities and exercise intolerance in renal transplant recipients., Journal of Nephrology. 2014.
Ma M.K., Kwan L.P., Mok M.M., Yap Y.H.D., Tang C.S. and Chan D.T.M., Significant reduction of Tacrolimus trough level after conversion from twice daily Prograf to once daily Advagraf in Chinese renal transplant recipients with or without concomitant diltiazem treatment, Renal Failure. 2013, 35: 942-945.
Mok C.C., Yap Y.H.D., Navarra S.V., Liu Z.H., Zhao M.H., Lu L., Takeuchi T., Avihingsanon Y., Yu X.Q., Lapid E.A., Lugue-Lizardo L.R., Sumethkul V., Shen N., Chen S.L., Chan D.T.M. and the Asian Lupus Nephritis Network (ALNN) , Overview of lupus nephritis management guidelines and perspective from Asia, International Journal of Rheumatic Diseases. 2013, 16(6): 625-636.
Mok C.C., Yap Y.H.D., Navarra S.V., Liu Z.H., Zhao M.H., Lu L., Takeuchi T., Avihingsanon Y., Yu X.Q., Lapid E.A., Lugue-Lizardo L.R., Sumethkul V., Shen N., Chen S.L., Chan D.T.M. and Asian Lupus Nephritis Network (ALNN) .., Overview of lupus nephritis management guidelines and perspective from Asia, Nephrology. 2014, 19: 11-20.
Mok M.M., Ma M.K., Yap Y.H.D., Chan D.T.M. and Lam M.F., Secondary atypical mycobacterial infection after peritoneal catheter removal, International Wound Journal. 2014, n/a-n/a.
Shea Y.F., Tsang H.H.L., Yap Y.H.D., Li L.F. and Ho W.W.S., A "tricky" subarachnoid hemorrhage, Chinese Medical Journal. 2013, 126(18): 3598.
Yap Y.H.D. and Chan D.T.M., An overview of current and future treatment methods for lupus nephritis, Expert Opinion Orphan Drugs. 2014, 2: 169-179.
Yap Y.H.D., Associate Editor, Hong Kong Journal of Nephrology. Elsevier, 2014.
Yap Y.H.D., Choy C.B.Y., Mok M.M., Wong T.K. and Chan D.T.M., Burkholderia cepacia-an uncommon cause of exit-site infection in a peritoneal dialysis patient, Peritoneal Dialysis International. 2014, 34(4): 471-472.
Yap Y.H.D., Chan G.S., Chan K.W., Kwan L.P., Wong W.T., Lam M.F. and Chan D.T.M., Cortical necrosis in a kidney transplant recipient due to leptospirosis, Nephrology. 2014, 19: 257-258.
Yap Y.H.D. and Chan D.T.M., Effect of long-term tacrolimus treatment in patients with lupus nephritis, European Renal Association - European Dialysis and Transplantation Association (ERA-EDTA) 51st Congress. 2014.
Yap Y.H.D., Yung S.S.Y., Tang C.S., Seto W.K.W., Ma M.K., Mok M.M., Kwan L.P., Chan G.C., Choy B.Y., Yuen R.M.F. and Chan D.T.M., Entecavir Treatment in Kidney Transplant Recipients Infected with Hepatitis B, Clinical Transplantation. 2014.
Yap Y.H.D. and Chan D.T.M., Evolution of hepatitis B management in kidney transplantation, World Journal of Gastroenterology. 2014, 20(2): 468-474.
Yap Y.H.D., Yung S.S.Y., Ma M.K., Mok M.M., Kwan L.P., Chan G.C. and Chan D.T.M., Serum immunoglobulin G level in patients with lupus nephritis and the effect of treatment with corticosteroids and mycophenolate mofetil, Lupus. 2014.
Yap Y.H.D., Serum immunoglobulin levels and mesangial cell-binding activity in patients with severe lupus nephritis , Hong Kong Society of Nephrology Annual Scientific Meeting 2013. 2013.
Yap Y.H.D. and Chan D.T.M., Treatment of lupus nephritis: practical issues in Asian countries, International Journal of Rheumatology Diseases. 2014, Epub ahead of print.


Researcher : Yau TCC

Project Title:The Role of Serial Changes in Circulating Angiogenic Markers in Predicting the Clinical Outcome of Advanced Hepatocellular Carcinoma (HCC) Patients on Sorafenib
Investigator(s):Yau TCC, Fan ST, Poon RTP, Pang RWC
Department:Surgery
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2011


Project Title:A Pilot Study to Evaluate the Prophylactic Effects of Telbivudine for Prevention of Hepatitis B Reactivation in HBsAg Positive Patients Receiving Sorafenib Treatment for Advanced Hepatocellular Carcinoma
Investigator(s):Yau TCC, Poon RTP
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:06/2012


Project Title:4th Biennial Congress of the Asian-Pacific Hepato-Pancreato-Biliary Association; Systemic treatment of metastatic neuroendocrine tumors to the liver/Local-regional therapy for colorectal liver metastases
Investigator(s):Yau TCC
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2013


Project Title:The Role of Insulin Growth Factor (IGF) Level in Cachexia and Treatment Outcome in Advanced Pancreatic Cancer Patients
Investigator(s):Yau TCC, Poon RTP
Department:Surgery
Source(s) of Funding:Small Project Funding
Start Date:06/2013


List of Research Outputs

Cheung P.S.Y., Tong A.C., Leung R.C.Y., Kwan W.H. and Yau T.C.C., Initial experience with the Oncotype DX assay in decision-making for adjuvant therapy of early oestrogen receptor–positive breast cancer in Hong Kong, Hong Kong Medical Journal. 2014, 20.
Cheung T.T., Chok K.S.H., Chan A.C.Y., Tsang S.H.Y., Dai W.C., Lang H.H.B., Yau T.C.C., Chan S.C., Poon R.T.P., Fan S.T. and Lo C.M., Long term survival analysis of hepatectomy for neuroendocrine tumour liver metastases, The Scientific World Journal. 2014, Epub on 2014-01-12.
Chiu J.W.Y., Tang Y.F., Leung R.C.Y., Wong H.Y.H., Chu K.W., Poon T.C.J., Epstein R. and Yau T.C.C., Efficacy and Tolerability of Adjuvant Oral Capecitabine plus Intravenous Oxaliplatin (XELOX) in Asian patients with Colorectal Cancer: 4-Year Analysis, Asia Pacific Journal of Cancer Prevention. 2013, 14: 6585-6590.
Huang G., Yeung C.Y., Lee K.K., Liu J., Ho K.L., Yiu M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu C.W., Androgen deprivation therapy and cardiovascular risk in Chinese patients with nonmetastatic carcinoma of prostate, Journal of Oncology. 2014, Epub on 2014-04-07.
Huang G., Yeung C.Y., LEE K.K., LIU J., Ho K.L., YIU M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu D.C.W., Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate., Journal of Oncology. Hindawi, 2014, 2014.
Yau T.C.C., 45 Years Old Gentleman with Pancreatic Neuroendocrine Tumour: Advances in the Therapeutic Options, Asia-Pacific Gastroenterology Cancer Summit 2013. 2013.
Yau T.C.C., Abraxane-An Overview of Clinical Efficacy, Celgene East Asia Clinical Management Meeting. 2014.
Yau T.C.C., Best Oral Abstract in Clinical Medicine (Abstract title not provided), 20th Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014.
Yau T.C.C., Clinical Medicine Oral Session Chairman, 20th Medical Research Conference, Department of Medicine, The University of Hong Kong, Hong Kong. 2014.
Yau T.C.C., Contemporary Strategies for Battling Breast Cancer D2 Summary, Eisai Symposium of Comtemporary Oncology 2014. 2014.
Yau T.C.C., Management of Ras Wild Type Metastatic Colorectal Cancer, GlaxoSmithKline Vertibix Launch Symposium. 2014.
Yau T.C.C., Member, GlaxoSmithKline Melanoma Advisory Board, Hong Kong. 2014.
Yau T.C.C., Member, Multidisciplinary Tumour Boards Panel, Asia-Pacific Gastroenterology Cancer Summit 2013, Singapore. 2013.
Yau T.C.C., Member, Sanofi Aflibercept Hong Kong Advisory Board, Hong Kong. 2013.
Yau T.C.C., Molecular Therapy of NETs, Inaugural Conference of The Asia Pacific Neuroendocrine Tumour Society. 2013.
Yau T.C.C., Neoadjuvant therapy of Advanced Pancreatic Cancer: Dream or Fallacy, Hong Kong Sanatorium Hospital Tumour Board Meeting. 2014.
Yau T.C.C., New Drug Development for Advanced Hepatocellular Carcinoma, Asian Oncology Summit 2014. 2014.
Yau T.C.C., New Perspective in the Targeted Therapy of Advanced Colorectal Cancer, Hong Kong Pathology Forum. 2014.
Yau T.C.C., Novel Targeted Therapies in the Management of Hepatocellular Carcinoma, Asia-Pacific Gastroenterology Cancer Summit 2013. 2013.
Yau T.C.C., Perspectives in Multidisciplinary Team Management of Metastatic Colorectal Cancer, The 11th Asia Pacific Congress of Endoscopic and Laparoscopic Surgery. 2013.
Yau T.C.C., Plenary Session Chairman, 20th Medical Research Conference, Department of Medicine, The University of Hong Kong, Hong Kong. 2014.
Yau T.C.C., Reviewer, Annals of Oncology. 2013.
Yau T.C.C., Reviewer, Cutaneous and Ocular Toxicology. 2014.
Yau T.C.C., Reviewer, Gastroenterology. 2014.
Yau T.C.C., Reviewer, Hepatic Oncology. 2014.
Yau T.C.C., San Antonio Updates of Breast Cancer 2013, Novartis San Antonio Breast Cancer Update Meeting. 2014.
Yau T.C.C., Session Chairman, Eisai Symposium of Comtemporary Oncology 2014, Jeju, South Korea. 2014.
Yau T.C.C., Therapeutic Advances in the Systemic Therapy of Hepatocellular Carcinoma, International Congress and the Third IASGO CME Postgraduate Course. 2014.
Yau T.C.C., Treatment for Refractory Colorectal Cancer: Any Hope in 2014?, Asian Oncology Summit 2014. 2014.
Zhu A.X., Borger D.R., Kim Y., Cosgrove D., Ejaz A., Alexandrescu S., Groeschl R.T., Deshpande V., Lindberg J.M., Ferrone C., Sempoux C., Yau T.C.C., Poon R.T.P., Popescu I., Bauer T.W., Gamblin T.C., Gigot J.F., Anders R.A. and Pawlik T.M., Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets, Annals of Surgical Oncology. 2014.


Researcher : Ye D

Project Title:Role of lipocalin-2 in nonalcoholic fatty liver disease
Investigator(s):Ye D, Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:Lipocalin-2 in acute and chronic liver diseases: focusing on neutrophil-mediated innate immune responses
Investigator(s):Ye D, Wang Y, Wong ICK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:10/2013


List of Research Outputs

Ye D., Wang Y., Li H., Jia W., Man K., Lo C.M., Wang Y., Lam K.S.L. and Xu A., Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice, Hepatology. 2014, Epub on 2014-02-06.


Researcher : Yeung CK

Project Title:HLA-B* 58:01 allele screening to reduce allopurinol-induced severe cutaneous reactions in patients with chronic kidney disease in Hong Kong
Investigator(s):Yeung CK, Tang SCW, Cheung BMY
Department:Medicine
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:01/2012


List of Research Outputs

Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Efficacy of high-intensity focused ultrasonography for noninvasive body sculpting in Chinese patients., Lasers in Surgery and Medicine. Wiley Online Library, 2014, 46(4): 263-9.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Efficiacy of a High-Intensity Focused Ultrasound Device for Non-invasive Body Contouring, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Non-invasive Cryolipolysis for Fat Reduction in Flanks in Chinese with a Modified Applicator , 19th Medical research Conference; Department of Medicine; Li KA Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., Safety and Efficacy Evaluation of a Combined Device Using Infrred Light and Bi-polar Radiofrequency and Sublative Radiofrequency Applicators, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Shek S.Y.N., Yeung C.K., Chan C.Y.J. and Chan H.H.L., The Efficacy of a Microwave Device for Treating Hyperhidrosis in Chinese, 19th Medical Research Conference; Department of Medicine; Li Ka Shing Faculty of Medicine; The University of Hong Kong. 2013.
Yiu K.H., Yeung C.K., Zhao C., Chan J.C., Siu D.C.W., Tam S., Wong C.S., Yan G.H., Yue W.S., Khong P.L., Cha H. and Tse H.F., Prevalence and extent of subclinical atherosclerosis in patients with psoriasis, J Intern Med. 2013, 3: 273-282.


Researcher : Yeung CY

List of Research Outputs

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Woo Y.C., Xu A., Fong H.Y., Ong K.L., Yeung C.Y., Janus E.D. and Tse H.F., Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study, European Journal of Endocrinology. 2014, 171: 107-115.
Huang G., Yeung C.Y., Lee K.K., Liu J., Ho K.L., Yiu M.K., Lam K.S.L., Tse H.F., Yau T.C.C. and Siu C.W., Androgen deprivation therapy and cardiovascular risk in Chinese patients with nonmetastatic carcinoma of prostate, Journal of Oncology. 2014, Epub on 2014-04-07.
Lam K.S.L., Hui Y.L.E., Yuen M.A.M., Yeung C.Y., Woo Y.C., Fong H.Y. and Xu A., Circulating fibroblast growth factor 21 level predicts the progression of diabetes nephropathy in patients with type 2 diabetes, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo, 17-24 Jun 2014, Chicago, USA.. 2014.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.
Leung E.L., Yeung C.Y., Yee A.S., Leung C.Y., Wong Y.F., Wong K.K. and Tan K.C.B., Effectiveness of a nurse-led treatment intensification program in treating type 2 DM patient with poor glycaemic control., Health Authority Convention in Hong Kong.. 2014.
Yeung C.Y., Hui Y.L.E., Lam T.H., Chow W.S., Woo Y.C., Fong H.Y., Xu A., Cheung B.M.Y. and Lam K.S.L., Plasma fibrinogen level as a predictor of incident metabolic syndrome in a community-based prospective study in Hong Kong Chinese, European Association for the Study of Diabetes. 2013.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.


Researcher : Yeung SC

List of Research Outputs

HAN Q., Yeung S.C., Ip M.S.M. and Mak J.C.W., Cellular mechanisms in intermittent hypoxia-induced cardiac damage in vivo, J Physiol Biochem. Springer, 2014, 70: 201-213.
HAN Q., Yeung S.C., Ip M.S.M. and Mak J.C.W., Intermittent hypoxia-induced NF-kB and HO-1 regulation in human endothelial EA.hy926 cells, Cell Biochem. Biophys.. 2013, 66: 431-441.
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
Wang Y., Yeung S.C., Ip M.S.M. and Mak J.C.W., Suppression of inflammation during adipogenic differentiation in human preadipocytes, 19th Medical Research Conference, The University of Hong Kong, Hong Kong Medical Journal. 2014, 20 (Supp 1): P 42 (68).


Researcher : Yiu KH

Project Title:Mechanism and Reversibility of Myocardial Fibrosis in Patients with Diabetic Cardiomyopathy: Role of Aliskiren.
Investigator(s):Yiu KH, Lam KSL, Tse HF, Wang MM
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Relationship between matrix G1a protein and osteogenic endothelial progenitor cells with vascular and valvular calcification in patients with rheumatoid arthritis: Potential therapeutic role of vitamin K
Investigator(s):Yiu KH, Lau WCS, Tse HF
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2013


List of Research Outputs

Jim M.H., Fung R.C., Yiu K.H., Ng A.K., Siu D.C.W. and Fan K.Y., Combined Paclitaxel-Eluting Balloon and Genous Cobalt-Chromium Alloy Stent Utilization in De Novo Coronary Stenoses (PEGASUS). , J Interv Cardiol. . 2013, 26(5): 556-560.
Lau G.K.K., Chan Y.H., Wong Y.K., Teo K.C., Yiu K.H., Liu S., Li L.S.W., Shu X.O., Ho S.L., Chan K.H., Siu D.C.W. and Tse H.F., Garlic intake is an independent predictor of endothelial function in patients with ischemic stroke, Journal of Nutrition, Health and Aging. 2013, 17(7): 600-604.
Lau G.K.K., Chan P.H.M., Yiu K.H., Chan Y.H., Liu S., Chan K.H., Yeung C.Y., Li L.S.W., Tse H.F. and Siu D.C.W., Roles of the CHADS2 and CHA2DS2-VASc scores in post-myocardial infarction patients: Risk of new occurrence of atrial fibrillation and ischemic stroke, Cardiology Journal. 2014.
Lee H.L.R., Chiu P.K.Y., Yiu K.H., Ng F.Y., Yan C.H. and Chan P.K., Perioperative Antithrombotic Management In Joint Replacement Surgeries, Hong Kong Medical Journal. 2013, 19: 531-8.
Yiu K.H., Invited Speaker, ESC 2013, The Netherlands “Predictive value of high-sensitivity troponin-l for adverse cardiovascular outcomes in patients with type 2 diabetes mellitus & “Electromechanical interplay in diabetic cardiomyopathy: relationship between diastolic dysfunction and T-wave alternans., 2013.
Yiu K.H., Chairperson, “ Cardiovascular Interventional Summit 2013 (CIS), “介入創新.新技術高峰論壇”Hong Kong College of Cardiology, 2013.
Yiu K.H., Distinguished Research Paper Award for Young Investigator 2014: Hong Kong College of Physician, 2014.
Yiu K.H., Invited Speaker, 7th Asia Pacific Cardiology Update USM 2013, Malaysia, “Evaluation for cardiac resynchronization device therapy, 2013.
Yiu K.H., Invited Speaker, Boehringer Lunch Symposium, “Preventing Stoke in Patients with Atrial Fibrillation with NOACs”, 2014.
Yiu K.H., Invited Speaker, EchoHK, “”4D echocardiography in clinical practice”, 2013.
Yiu K.H., Invited Speaker, Hong Kong College of Cardiology, “Prevention of Stroke in East Asian AF Patients”, 2014.
Yiu K.H., Invited Speaker, The University of Hong Kong-Shenzhen Hospital Pharmacy Department, “Therapeutic management of heart failure”, 2014.
Yiu K.H., Invited Speaker, “ 第十二中國介入心臟病學大會上海2014”, 2014.
Yiu K.H., Merck Serono Cardiovascular Scientific Forum Macau 2014” Cardioprotective role of beta-blockers in Hypertension and Other Comorbidities , 2014.
Yiu K.H., Lau G.K.K., Zhao C., Chan Y.H., Chen Y., Zhen Z., Wong A., Lau C.P. and Tse H.F., Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus, Cardiovascular Diabetology. 2014, 13:63: 1-8.
Yiu K.H., Yeung C.K., Zhao C., Chan J.C., Siu D.C.W., Tam S., Wong C.S., Yan G.H., Yue W.S., Khong P.L., Cha H. and Tse H.F., Prevalence and extent of subclinical atherosclerosis in patients with psoriasis, J Intern Med. 2013, 3: 273-282.
Yiu K.H., Wong A., Pu L., Chiang R., Sit K.Y., Chan D., Lee H.Y., Lam Y.M., Chen Y., Siu D.C.W., Lau C.P., Au K.W. and Tse H.F., Prognostic value of preoperative right ventricular geometry and tricuspid valve tethering area in patients undergoing tricuspid annuloplasty, Circulation. 2014, 129: 87-92.
Yiu K.H. and Tse H.F., Specific role of impaired glucose metabolism and diabetes in endothelial progenitor cell characteristics and function., Arterioscler Thromb Vasc Biol. 2014, 34: 1136-1143.
Yiu K.H., •2014 : Supervisor of the Best Abstract Awards in Poster Presentation in Clinical Medicine (poster), 19th Medical Research Conference, Department of Medicine, The University of Hong Kong Best Abstract in Clinical Medicine (Poster), Yan Chen Division of Cardiology, Assessment of Carotid Intima-media Thickness in Patients with Axial Spondyloarthritis: Relationship with Disease Severity, 2014.
Zuo M., Yue W., Yip T., Ng F., Lam K.F., Yiu K.H., Lui S.L., Tse H.F., Siu D.C.W. and Lo W.K., Prevalence of and Associations With Reduced Exercise Capacity in Peritoneal Dialysis Patients, In: Andrew S. Levey, Daniel E. Weiner, American Journal of Kidney Diseases. Elsevier, 2013, 62: 939-946.


Researcher : Yiu WH

Project Title:ASN Kidney Week 2013 Annual Meeting ; Tissue Kallikrein Mediates Pro-inflammatory Pathways in Proximal Tubular Epithelial Cells
Investigator(s):Yiu WH
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2013


Project Title:The role of coagulation system in renal fibrosis
Investigator(s):Yiu WH, Tang SCW
Department:Medicine
Source(s) of Funding:Small Project Funding
Start Date:01/2014


List of Research Outputs

LI R., Yiu W.H., Wu H., LIN M., WONG W.L.D., Chan Y.Y., Leung J.C.K., Lai K.N. and Tang S.C.W., Role of Bone Morphogenetic Protein-7 (BMP7) in Diabetic Tubulopathy, J Am Soc Nephrol. 2013, 24: 697A.
Leung J.C.K., Lim A.I., Chan Y.Y., Yiu W.H., Lai K.N. and Tang S.C.W., Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) Represses Albumin-Induced Chemokines and Adhesion Molecules Synthesis by Kidney Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 135A.
Lim A.I., Chan Y.Y., Tang S.C.W., Yiu W.H., LI R., Lai K.N. and Leung J.C.K., BMP-7 represses albumin-induced chemokine synthesis in kidney tubular epithelial cells through destabilization of NF-κB-inducing kinase., Immunol Cell Biol.. 2014, 92(5): 427-35.
WONG W.L.D., Yiu W.H., Wu H., LI R., Leung J.C.K., Chan Y.Y., Lai K.N. and Tang S.C.W., Protein Overload Induces Renal Proximal Tubular Epithelial Cell Apoptosis by Down-Regulating WNT/β-Catenin Signalling, J Am Soc Nephrol. 2013, 24: 409A.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
Yiu W.H., WONG W.L.D., Leung J.C.K., Chan Y.Y., Lan H.Y., Lai K.N. and Tang S.C.W., Tissue Kallikrein Mediates Pro-Inflammatory Pathways in Proximal Tubular Epithelial Cells, J Am Soc Nephrol. 2013, 24: 315A.
Yiu W.H., WONG W.L.D., Chan Y.Y., Leung J.C.K., Chan K.W., lan H.Y., Lai K.N. and Tang S.C.W., Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells., PLoS One. 2014, 9 (2): e88894.


Researcher : Yue W

List of Research Outputs

Zuo M., Yue W., Yip T., Ng F., Lam K.F., Yiu K.H., Lui S.L., Tse H.F., Siu D.C.W. and Lo W.K., Prevalence of and Associations With Reduced Exercise Capacity in Peritoneal Dialysis Patients, In: Andrew S. Levey, Daniel E. Weiner, American Journal of Kidney Diseases. Elsevier, 2013, 62: 939-946.


Researcher : Yuen JCH

List of Research Outputs

Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.
Zheng M.H., Seto W.K.W., Shi K.Q., Wong D.K.H., Fung J.Y.Y., Hung I.F.N., Fong D.Y.T., Yuen J.C.H., Tong T., Lai C.L. and Yuen R.M.F., Artificial neural network accurately predicts hepatitis B surface antigen seroclearance, PLoS One. 2014, 9(6): e99422.


Researcher : Yuen KYC

List of Research Outputs

Lau W.C.S., Au Y.L., Chan Y.Y., Chan Y.T., Chan O.W., Cheung T.T., Chung H.Y., Ho C.T.K., Kowk S.K., Lee W.S., Li W.L., Lui M.S., Mok T.M.Y., Tang L.M., Tsang H.L., Yuen K.Y.C. and Wong R.W.S., Outstanding Team 2014, Hong Kong West Cluster cum Queen Mary Hospital. 2014.
Mok C.C., Tam L.S., Leung M.H., Ying K.Y., To C.H., Lee K.L., Ho L.Y., Yip M.L., Tsui H.S., Chan T.H., Lee K.W., Li E.K., Hong Kong Society of Rheumatology , Chan E.Y., Chan K.H., Chan K.M., Chan K.Y., Chan P.S., Chan Y.K., Chau S.Y., Cheung T.C., Cheung T.T., Chung H.Y., Ho C.T.K., Kun E., Kwok L.W., Kwok M.L., Kwok K., Lam C.K., Lao W.N., Lau W.C.S., Lau Y.L., Lee A.K., Lee T.K., Lee K.K., Lee M.Y., Lee S.S., Lee T.L., Yan T., Leung M.C., Li W.L., Liu H.M., Luk M.C., Ma K.Y., Mak L.W., Mok T.M.Y., Ng K.H., Ng W.L., So H., Sung C.K., Tan R.F., Tang S.K., Wan M.C., Wong C.H., Wong K.C., Man S., Wong P.Y., Wong J., Wong R.W.S., Woo W.S., Young K.Y., Yim C.W., Yu K.L., Yuen K.Y.C. and Yung K.M., Referral strategy for early recognition of axial spondyloarthritis: consensus recommendations from the Hong Kong Society of Rheumatology., Int J Rheum Dis. 2013, 16(5): 500-8.


Researcher : Yuen MAM

List of Research Outputs

Lam K.S.L., Hui Y.L.E., Yuen M.A.M., Yeung C.Y., Woo Y.C., Fong H.Y. and Xu A., Circulating fibroblast growth factor 21 level predicts the progression of diabetes nephropathy in patients with type 2 diabetes, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo, 17-24 Jun 2014, Chicago, USA.. 2014.


Researcher : Yuen MF

Project Title:An open label study of adefovir dipivoxil for the treatment of patients with chronic hepatitis B (CHB) related advanced fibrosis or cirrhosis
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:Glaxo Wellcome Hong Kong Ltd. - General Award
Start Date:07/2005


Project Title:Randomized, open-label, comparative study to evaluate early viral load reductions and exploratory viral kinetics following administration of entecavir or adefovir in nucleoside-naïve adults with chronic hepatitis B infection
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:Bristol-Myers-Squibb (HK) - General Award
Start Date:01/2006


Project Title:A phase I, multi-centre, randomised, placebo-controlled, dose escalation study to assess the local and systemic tolerability of the therapeutic DNA plasmid pdpSC18 vaccine administered by particle mediated epidermal delivery using the powderject ND 10 delivery system in subjects with chronic hepatitis B infection
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:PowderMed Ltd - General Award
Start Date:11/2006


Project Title:Significance of HBV DNA in the natural history of chronic hepatitis B: impact on disease outcome including significant fibrosis and hepatocellular carcinoma
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:Bristol-Myers-Squibb (HK) - General Award
Start Date:09/2007


Project Title:Virological and clinico-pathological factors in estimating the chance of recurrence of hepatocellular carcinoma after surgical resection in patients with Chronic Hepatitis B
Investigator(s):Yuen RMF, Hung IFN, Poon RTP, Fong DYT, Wong DKH, Lai CL
Department:Medicine
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:01/2010


Project Title:Outstanding Researcher Award 2009-10
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:Outstanding Researcher Award
Start Date:12/2010


List of Research Outputs



Researcher : Yuen RMF

Project Title:An open label study of adefovir dipivoxil for the treatment of patients with chronic hepatitis B (CHB) related advanced fibrosis or cirrhosis
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:Glaxo Wellcome Hong Kong Ltd. - General Award
Start Date:07/2005


Project Title:Randomized, open-label, comparative study to evaluate early viral load reductions and exploratory viral kinetics following administration of entecavir or adefovir in nucleoside-naïve adults with chronic hepatitis B infection
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:Bristol-Myers-Squibb (HK) - General Award
Start Date:01/2006


Project Title:A phase I, multi-centre, randomised, placebo-controlled, dose escalation study to assess the local and systemic tolerability of the therapeutic DNA plasmid pdpSC18 vaccine administered by particle mediated epidermal delivery using the powderject ND 10 delivery system in subjects with chronic hepatitis B infection
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:PowderMed Ltd - General Award
Start Date:11/2006


Project Title:Significance of HBV DNA in the natural history of chronic hepatitis B: impact on disease outcome including significant fibrosis and hepatocellular carcinoma
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:Bristol-Myers-Squibb (HK) - General Award
Start Date:09/2007


Project Title:Virological and clinico-pathological factors in estimating the chance of recurrence of hepatocellular carcinoma after surgical resection in patients with Chronic Hepatitis B
Investigator(s):Yuen RMF, Hung IFN, Poon RTP, Fong DYT, Wong DKH, Lai CL
Department:Medicine
Source(s) of Funding:Research Fund for the Control of Infectious Diseases - Full Grants
Start Date:01/2010


Project Title:Outstanding Researcher Award 2009-10
Investigator(s):Yuen RMF
Department:Medicine
Source(s) of Funding:Outstanding Researcher Award
Start Date:12/2010


List of Research Outputs

CHEUNG F., Wang X., Wang N., Yuen R.M.F., Zia T.C., Tong Y., Wong V.C.W. and Feng Y., Chinese Medicines as an Adjuvant Therapy for Unresectable Hepatocellular Carcinoma during Transarterial Chemoembolization: A Meta-Analysis of Randomized Controlled Trials, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2013, 2013:487919.: doi: 10.1155/2013/487919.
Ferrante S.A., Yuen R.M.F., Wong V.W., Loo C.K., Chhatwal J. and Elbasha E., Cost-Effectiveness Modeling Study of boceprevir for the treatment of patients with genotype 1 chronic hepatitis C virus infection in Hong Kong, Poster presentation at the 64th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2013. Hepatology. 2013, 58(4)(Suppl): 186A.
Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Defining Normal Liver Stiffness Range in a Normal Healthy Chinese Population without Liver Disease, PLoS One. 2013, 8(12): e85067.
Fung J.Y.Y., Seto W.K.W., Lai C.L. and Yuen R.M.F., Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment, Journal of Gastroenterology and Hepatology. Blackwell Publishing, 2014, 29(3): 428-434.
Fung J.Y.Y., Seto W.K.W., Wong D.K.H., Lai C.L. and Yuen R.M.F., Hepatitis B surface antigen levels after hepatitis B e-antigen seroclearance: a longitudinal follow-up study, Liver Int. 2014.
Fung J.Y.Y., Lee C.K., Chan M., Seto W.K.W., Lai C.L. and Yuen R.M.F., High Prevalence of Non-Alcoholic Fatty Liver Disease in the Chinese - Results from the Hong Kong Liver Health Census, Liver Int. 2014.
Fung J.Y.Y., Lo C.L.R., Chan S.C., Chok K.S.H., Sharr W.W., Dai W.C., Cheung T.T., Chan A.C.Y., Wong C.L.T., Ng I.O.L., Yuen R.M.F. and Lo C.M., Histological outcome after liver transplantation for chronic hepatitis B using oral antiviral therapy alone without hepatitis B immune globulin, The 2014 Joint International Congress of ILTS, ELITA & LICAGE. 2014.
Fung J.Y.Y., Lai C.L., Wong D.K.H., Seto W.K.W., Kopaniszen M. and Yuen R.M.F., Level of hepatitis B surface antigen and not HBV DNA level after HBeAg seroclearance is predictive of HBsAg seroclearance, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S259.
Fung J.Y.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Spontaneous hepatitis B e-antigen seroconversion without subsequent antiviral therapy is associated with higher rates of hepatitis B surface antigen seroclearance, Annual Meeting, American Association for the Study of Liver Disease. 2013.
Fung J.Y.Y., Poon R.T.P., Yu W.C., Chan S.C., Chan A.C.Y., Chok K.S.H., Cheung T.T., Seto W.K.W., Lo C.M., Lai C.L. and Yuen R.M.F., Use of liver stiffness measurement for liver resection surgery: correlation with indocyanine green clearance testing and post-operative outcome, PLoS One. 2013, 8(8): e72306.
Huang F.Y., Wong D.K.H., Seto W.K.W., Lai C.L. and Yuen R.M.F., Estrogen represses anti-apoptotic genes expression via MiR-23a: contribution to sex differences in the development of hepatocellular carcinoma, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 667). Hepatology International. 2014, 8(S1): S243.
Huang F.Y., Wong D.K.H., Seto W.K.W., Zhang A.Y., Lee C.K., Lin C.K., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Sequence Variations of Full-Length Hepatitis B Virus Genomes in Chinese Patients with HBsAg-Negative Hepatitis B Infection, PLoS One. 2014, 9(6): e99028.
Hung I.F.N., Wong D.K.H., Fong D.Y.T., Chui A.H., Seto W.K.W., Fung J.Y.Y., Yuen J.C.H., Tiu T.M.R.J., Tsoi Y.Y.O., Lai C.L., Poon R.T.P. and Yuen R.M.F., Virological and clinico-pathological factors in predicting recurrence of hepatitis B related hepatocellular carcinoma after surgical resection, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S258-9.
Lai C.L., Ahn S.H., Lee K.S., Um S.H., Cho M., Yoon S.K., Lee J.W., Park N.H., Kweon Y.O., Sohn J.H., Lee J., Kim J.A., Han K.H. and Yuen R.M.F., Phase IIb multicentred randomised trial of besifovir (LB80380) versus entecavir in Asian patients with chronic hepatitis B, Gut. BMJ Publishing Group, 2013, 63(6): 996-1004.
Lai C.L. and Yuen R.M.F., Reply, Hepatology. John Wiley and Sons Ltd, 2013, 58(5): 1857.
Lam Y.F., Wong D.K.H., Seto W.K.W., To K.K.W., Hung I.F.N., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., HLA-DP and interferon gamma receptor-2 gene variants and their association with viral hepatitis activity in chronic hepatitis B infection., Journal of Gastroenterology and Hepatology. 2014, 29(3): 533-539.
Leung W.K., Liu K.S.H., Seto W.K.W., Chan K.H., Tong S.M., Yuen R.M.F. and Hung I.F.N., Factors for hepatitis B vaccination and abnormal liver function in Chinese patients with inflammatory bowel disease: a single center experience, J Dig Dis. 2013, 14: 596-603.
Lin X.F., Shi K.Q., You J., Liu W.Y., Luo Y.W., Wu F.L., Chen Y.P., Wong D.K.H., Yuen R.M.F. and Zheng M.H., Increased risk of colorectal malignant neoplasm in patients with nonalcoholic fatty liver disease: a large study, Molecular Biology Reports. Springer Netherlands, 2014, 41(5): 2989-97.
Lu T., Seto W.K.W., Zhu R.X., Lai C.L. and Yuen R.M.F., Prevention of hepatocellular carcinoma in chronic viral hepatitis B and C infection, World J Gastroenterol. 2013, 19(47): 8887-8894.
Nishida N., Sawai H., Kashiwase K., Minami M., Sugiyama M., Seto W.K.W., Yuen R.M.F., Posuwan N., Poovorawan Y., Ahn S.H., Han K.H., Matsuura K., Tanaka Y., Kurosaki M., Asahina Y., Izumi N., Kang J.H., Hige S., Ide T., Yamamoto K., Sakaida I., Murawaki Y., Itoh Y., Tamori A., Orito E., Hiasa Y., Honda M., Kaneko S., Mita E., Suzuki K., Hino K., Tanaka E., Mochida S., Watanabe M., Eguchi Y., Masaki N., Murata K., Korenaga M., Mawatari Y., Ohashi J., Kawashima M., Tokunaga K. and Mizokami M., New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia, PLoS One. 2014, 9(2): e86449.
Nishida N., Sawai H., Kashiwase K., Minami M., Sugiyama M., Seto W.K.W., Yuen R.M.F., Poovorawan Y., Ahn S.H., Han K.H., Matsuura K., Tanaka Y., Kurosaki M., Asahina Y., Izumi N., Kang J.H., Hige S., Ide T., Yamamoto K., Sakaida I., Murawaki Y., Itoh Y., Tamori A., Orito E., Hiasa Y., Honda M., Kaneko S., Mita E., Suzuki K., Hino K., Tanaka E., Mochida S., Watanabe M., Eguchi Y., Korenaga M., Mawatari Y., Kawashima M., Tokunaga K. and Mizokami M., Trans-ethnic analyses of HLA-DPA1, DPB1 haplotypes to be associated with hepatitis B virus infection, Poster presentation at the 64th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2013. Hepatology. 2013, 58(4)(Suppl): 102A.
Seto W.K.W., Lam Y.F., Fung J.Y.Y., Wong D.K.H., Huang F.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Changes of HBsAg and HBV DNA levels in Chinese chronic hepatitis B patients after five years of entecavir treatment, J Gastroenterol Hepatol. 2013, 29(5): 1028-34.
Seto W.K.W., Lam Y.F., Liu S.H.K., Mak L.Y., Ko K.L.M., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Continuous Entecavir for Treatment-Naïve Chinese Chronic Hepatitis B in the Real World Setting: The Six-Year Results, Digestive Diseases Week 2014. Gastroenterology. 2014, 146(5): Suppl 1: S963-4.
Seto W.K.W., Hui A.J., Wong V.W.S., Wong G.L.H., Liu K., Lai C.L., Yuen R.M.F. and Chan H.L.Y., HBsAg and HBV DNA levels guiding entecavir cessation in HBeAg-negative chronic hepatitis B, Poster Presentation at the Gastro 2013 APDW/WCOG Shanghai, Asian Pacific Digestive Week 2013 ∣ World Congress of Gastroenterology, 21-24 September 2013, Shanghai, China. Journal of Gastroenterology and Hepatology. 2013, 28(Suppl 3): 414.
Seto W.K.W., Lai C.L. and Yuen R.M.F., Hepatitis viruses and hepatocellular carcinoma (Chapter 23), In: Prof. Shosuke Kawanishi (Suzuka University of Medical Science, Japan) and Prof. Hiroshi Ohshima (University of Shizuoka, Japan). , Cancer and Inflammation Mechanisms: Chemical, Biological and Clinical Aspects. 2014.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing hematopoietic stem cell transplant: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Chan T.S., Hwang Y.Y.G., Choi O., Wong D.K.H., Fung J.Y.Y., Lie A.K.W., Lai C.L., Kwong Y.L. and Yuen R.M.F., Interim analysis of hepatitis B reactivation in patients with prior HBV exposure undergoing rituximab-containing chemotherapy: a prospective study, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Liu K.S.H., Lai C.L. and Yuen R.M.F., Linearized hepatitis B surface antigen and hepatitis B core-related antigen in the natural history of chronic hepatitis B, Clinical Microbiology and Infection. 2014.
Seto W.K.W., Tanaka Y., Shinkai N., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Performance of a highly sensitive hepatitis B surface antigen assay among chronic hepatitis B patients after hepatitis B surface antigen seroclearance, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014. (Absno. 208). Hepatology International. 2014, 8(S1): S69.
Seto W.K.W., Wong D.K.H., Fung J.Y.Y., Huang F.Y., Lai C.L. and Yuen R.M.F., Reduction of hepatitis B surface antigen levels and hepatitis B surface antigen seroclearance in chronic hepatitis B patients receiving 10 years of nucleoside analogue therapy, Hepatology. 2013, 58(3): 923-31.
Seto W.K.W., Tsang O.T., Liu K., Chan J.M., Wong D.K.H., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection, Journal of Viral Hepatitis. 2013, 20(7): 470-7.
Seto W.K.W., Hui A.J., Wong V.W., Wong G.L., Liu K.S., Lai C.L., Yuen R.M.F. and Chan H.L., Treatment cessation of entecavir in Asian patients with hepatitis B e antigen negative chronic hepatitis B: a multicentre prospective study, Gut. 2014.
Shi K.Q., Wu F.L., Liu W.Y., Zhao C.C., Chen C.X., Xie Y.Y., Wu S.J., Lin X.F., Chen Y.P., Wong D.K.H., Yuen R.M.F. and Zheng M.H., Non-alcoholic fatty liver disease and risk of in-stent restenosis after bare metal stenting in native coronary arteries, Molecular Biology Reports. Springer Netherlands, 2014.
Wong D.K.H., Tsoi Y.Y.O., Huang F.Y., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Application of co-amplification at lower denaturation temperature-PCR (COLD-PCR) sequencing for the early detection of antiviral drug resistance mutations of hepatitis B virus, Journal of Clinical Microbiology. 2014.
Wong D.K.H., LIN S.C., Huang F.Y., Tsoi Y.Y.O., Seto W.K.W., Fung J.Y.Y., Lai C.L. and Yuen R.M.F., Association of methylated histones and DNA methylases with hepatitis B virus covalently closed circular DNA and their association with hepatitis B virus replication, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S214.
Wong D.K.H., Kopaniszen M., Omagari K., Tanaka Y., Fong D.Y.T., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Zhang A.Y., Hung I.F.N., Lai C.L. and Yuen R.M.F., Effect of Hepatitis B Virus Reverse Transcriptase Variations on Entecavir Treatment Response, Journal of Infectious Diseases. 2014.
Wong D.K.H., Fung J.Y.Y., Lee C.K., Seto W.K.W., Leung J., Huang D.K.H., Lin C.K., Lai C.L. and Yuen R.M.F., Hepatitis B virus serological and virological activities in blood donors with occult hepatitis B, 23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2014), Brisbane, Australia, March 12-15, 2014.(Absno: 868). Hepatology International. 2014, 8(S1): S149.
Wong D.K.H., Lai C.L., Ip P.P.C., Kopaniszen M., Seto W.K.W., Fung J.Y.Y., Huang F.Y., Wu C.H., Cheng C.T.K., Ngai W.S. and Yuen R.M.F., The effect of long-term nucleoside/tide analogue treatment on intrahepatic HBVDNA and covalently closed circular DNA in chronic hepatitis B patients, Poster presentation at the International Liver Congress™ 2014 – 49th Annual meeting of the European Association for the Study of the Liver. Journal of hepatology : the journal of the European Association for the Study of the Liver. 2014, 60(1): S435.
Yap Y.H.D., Yung S.S.Y., Tang C.S., Seto W.K.W., Ma M.K., Mok M.M., Kwan L.P., Chan G.C., Choy B.Y., Yuen R.M.F. and Chan D.T.M., Entecavir Treatment in Kidney Transplant Recipients Infected with Hepatitis B, Clinical Transplantation. 2014.
Yuen R.M.F., Antiviral therapy in acute-on-chronic liver failure, APASL-ACLF Research Consortium (AARC), New Dehli, India, February 22-23. 2014.
Yuen R.M.F., Antiviral treatment update: Are we achieving our treatment goal? , Asian Pacific Association for the Study of Liver – Single Topic Conference, Jakarta, Indonesia, November 30 –December 1. 2013.
Yuen R.M.F., Antiviral treatment: Are we achieving our treatment goals?, Beyond clinical trial: Chronic hepatitis B updates in Asia Pacific, Kuala Lumpur, Malaysia, March 8. 2014.
Yuen R.M.F., Controversies in Liver Diseases: chronic hepatitis , Multi-specialty Medical Mega conference, Hong Kong, May 3-4. 2014.
Yuen R.M.F., Convenor, Recommendations for the management of chronic hepatitis B infection – Expert Panel Meeding, December 7-8. 2013.
Yuen R.M.F., Editorial Board Member, Gut and Liver, Member of Editorial Board . 2013.
Yuen R.M.F., Epidemiology and risk factors in the Asia-Pacific, Conjoint APASL/ AASLD Symposium Hepatocellular Carcinoma, APASL, Brisbane, Australia, March 12-15. 2014.
Yuen R.M.F., HBsAg-negative hepatitis B disease, Master’s perspectives on chronic viral hepatitis and HCC. TASL Single Topic Conference, Taipei, Taiwan. 2013.
Yuen R.M.F., How to interpret liver function test?, CME Lecture, Shatin International Medical Centre, Union Hospital, Hong Kong. 2013.
Yuen R.M.F., Internal Medicine. 2013.
Yuen R.M.F., Internal Reviewer, AXA Research Fund – Post-doctoral Fellowships 2014, The University of Hong Kong. 2013.
Yuen R.M.F., Member, Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association of the Study to the Liver (APASL) 2014. 2014.
Yuen R.M.F., Updates in antiviral: Are we treating CHB patients to reduce ultimate end-points?, Annual Scientific Meeting, Macao Society of Gastroenterology and Hepatology, Macau. 2013.
Yuen R.M.F., Who should be treated? , Expert Panel Meeting for the Management of Chronic Hepatitis B, Hong Kong, December 7 – 8 . 2013.
ZHANG A., Wong D.K.H., Huang F.Y., Fung J.Y.Y., Seto W.K.W., Poon R.T.P., Lai C.L. and Yuen R.M.F., Characterization of intrahepatic HBV quasispecies genetic variability within the pre-S region in patients with HBV-related hepatocellular carcinoma, Liver Meeting, American Association for the Study of Liver Disease. 2013.
Zheng M.H., Seto W.K.W., Shi K.Q., Wong D.K.H., Fung J.Y.Y., Hung I.F.N., Fong D.Y.T., Yuen J.C.H., Tong T., Lai C.L. and Yuen R.M.F., Artificial neural network accurately predicts hepatitis B surface antigen seroclearance, PLoS One. 2014, 9(6): e99422.


Researcher : Yung SSY

Project Title:The role of annexin II and IL-6 in peritoneal inflammation and fibrosis
Investigator(s):Yung SSY, Chan DTM
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012
Completion Date:04/2014


Project Title:The Role of Fibronectin in Peritoneal Inflammation and Fibrosis
Investigator(s):Yung SSY, Chan DTM
Department:Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:The role of microRNAs in fibrogenic processes in mesothelial cells
Investigator(s):Yung SSY, Chan DTM
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013


Project Title:ASN Kidney Week 2013 Annual Meeting; Hyaluronan Exacerbates Renal Fibrosis in NZB/W Mice through Increased MCP-1 and TGF-β1 Secretion by Mesangial Cells
Investigator(s):Yung SSY
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2013
Completion Date:11/2013


Project Title:The role of hyaluronan in peritoneal inflammation and fibrosis
Investigator(s):Yung SSY, Chan DTM
Department:Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

LAM S.N., Yung S.S.Y., Chan D.T.M., Tsao G.S.W. and Wong A.S.T., MicroRNA-145, a p70 S6 kinase-activated microRNA, regulates N-cadherin expression and epithelial-mesenchymal transition, 17thECCO - 28thESMO - 32ndESTRO European Cancer Congress, Amsterdam, Netherlands. 2013.
Li Y., Huang C., Zhao M., Liang G., Xiao R., Yung S.S.Y., Chan D.T.M. and Lu Q., A possible role of HMGB1 in DNA demethylation in CD4+ T Cells from patients with systemic lupus erythematosus, Clin Dev Immunol. 2013, Epub.
TSUN G.S., Shiu S.W.M., Wong Y., Yung S.S.Y., Chan D.T.M. and Tan K.C.B., Impact of serum amyloid A on cellular cholesterol efflux to serum in type 2 diabetes mellitus., Atherosclerosis.. 2013, 231: 405-10.
Tan K.C.B., TSUN G.S., Yung S.S.Y., Chau K.M., Shiu S.W.M. and Chan D.T.M., Cholesterol transport proteins and diabetic nephropathy., World Diabetes Congress in Melbourne, Australia.. 2013.
Yap Y.H.D., Yung S.S.Y., Tang C.S., Seto W.K.W., Ma M.K., Mok M.M., Kwan L.P., Chan G.C., Choy B.Y., Yuen R.M.F. and Chan D.T.M., Entecavir Treatment in Kidney Transplant Recipients Infected with Hepatitis B, Clinical Transplantation. 2014.
Yap Y.H.D., Yung S.S.Y., Ma M.K., Mok M.M., Kwan L.P., Chan G.C. and Chan D.T.M., Serum immunoglobulin G level in patients with lupus nephritis and the effect of treatment with corticosteroids and mycophenolate mofetil, Lupus. 2014.


Researcher : ZHANG A

List of Research Outputs

ZHANG A., Wong D.K.H., Huang F.Y., Fung J.Y.Y., Seto W.K.W., Poon R.T.P., Lai C.L. and Yuen R.M.F., Characterization of intrahepatic HBV quasispecies genetic variability within the pre-S region in patients with HBV-related hepatocellular carcinoma, Liver Meeting, American Association for the Study of Liver Disease. 2013.


Researcher : ZHANG J

List of Research Outputs

ZHANG J., Ho J.C.Y., Chan Y.C., Lian Q., Siu D.C.W. and Tse H.F., Overexpression of myocardin induces partial transdifferentiation of human-induced pluripotent stem cell-derived mesenchymal stem cells into cardiomyocytes, Physiological Reports. 2014, 2: n/a-n/a.


Researcher : ZHANG M

List of Research Outputs

Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
XIE B., ZHANG M., Mak H.K.F. and Cheung R.T.F., Blood pressure variability, silent cerebrovascular lesions and cognitive impairment in healthy hypertensive elderly Chinese, 18th Research Postgraduate Symposium. 2013, 3.18.
XIE B., ZHANG M., Mak H.K.F. and Cheung R.T.F., Visit-to-visit blood pressure variability is associated with periventricular white matter hyperintensity in healthy hypertensive elderly Chinese, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 46.
ZHANG M., XIE B., Mak H.K.F. and Cheung R.T.F., Absence of association between arterial stiffness and white matter hyperintensities in otherwise healthy hypertensive elderly Chinese, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 51.
ZHANG M., XIE B., Mak H.K.F. and Cheung R.T.F., Arterial stiffness and white matter hyperintensities in healthy hypertensive elderly Chinese, 18th Research Postgraduate Symposium. 2013, 5.26.


Researcher : ZHANG Y

List of Research Outputs

Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
ZHANG Y., Yue J., CHE H., Sun H., Tse H.F. and Li G.R., BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells., J Cell Physiol. . 2013, 229(2): 202-212.
ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : ZHANG Y

List of Research Outputs

Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
ZHANG Y., Yue J., CHE H., Sun H., Tse H.F. and Li G.R., BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells., J Cell Physiol. . 2013, 229(2): 202-212.
ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : ZHANG Y

List of Research Outputs

Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
ZHANG Y., Yue J., CHE H., Sun H., Tse H.F. and Li G.R., BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells., J Cell Physiol. . 2013, 229(2): 202-212.
ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : ZHENG C

List of Research Outputs

LI Y., Lam S.K., ZHENG C. and Ho J.C.M., The Role of Autophagy Induced by Tyrosine Kinase Inhibitors in Non-small Cell Lung Carcinoma, 15th World Conference on Lung Cancer. 2013.
LI Y., Lam S.K., ZHENG C. and Ho J.C.M., The Role of Autophagy Induced by Tyrosine Kinase Inhibitors in Non-small Cell Lung Carcinoma, 20th Hong Kong International Cancer Congress. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo , 15th World Conference on Lung Cancer. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Downregulation of Thymidylate Synthase with Arsenic Trioxide in Non-Small Cell Lung Cancer: in vitro and in vivo , 20th Hong Kong International Cancer Congress. 2013.
Lam S.K., Mak J.C.W., ZHENG C., LI Y., Kwong Y.L. and Ho J.C.M., Downregulation of thymidylate synthase with arsenic trioxide in lung adenocarcinoma, International Journal of Oncology. 2014, 44: 2093-2102.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Dual Action of Arsenic Trioxide on Thymidylate Synthase and Apoptosis in Mesothelioma , Conference on joining hands to eliminate asbestos hazards. 2013.
Lam S.K., LI Y., ZHENG C. and Ho J.C.M., Dual action of arsenic trioxide on thymidylate synthase and apoptosis in mesothelioma, Conference on joining hands to eliminate asbestos hazards, Pneumoconiosis Compensation Fund Board, Hong Kong. 2013.
ZHENG C., Lam S.K., LI Y., Fong B.M., Mak J.C.W. and Ho J.C.M., Combination of arsenic trioxide and chemotherapy in small cell lung cancer, Lung Cancer. 2013, 82(2): 222-230.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, 15th World Conference on Lung Cancer. 2013.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, 20th Hong Kong International Cancer Congress. 2013.
ZHENG C., Lam S.K., LI Y. and Ho J.C.M., Genetic Alterations and Cellular Properties of Acquired Arsenic Resistance in Small Cell Lung Cancer, Journal of Thoracic Oncology. 2013, 8: S1041.


Researcher : Zhang M

List of Research Outputs

Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
XIE B., ZHANG M., Mak H.K.F. and Cheung R.T.F., Blood pressure variability, silent cerebrovascular lesions and cognitive impairment in healthy hypertensive elderly Chinese, 18th Research Postgraduate Symposium. 2013, 3.18.
XIE B., ZHANG M., Mak H.K.F. and Cheung R.T.F., Visit-to-visit blood pressure variability is associated with periventricular white matter hyperintensity in healthy hypertensive elderly Chinese, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 46.
ZHANG M., XIE B., Mak H.K.F. and Cheung R.T.F., Absence of association between arterial stiffness and white matter hyperintensities in otherwise healthy hypertensive elderly Chinese, Nineteenth Medical Research Conference, Department of Medicine, The University of Hong Kong. 2014, 20 (supp 1): 51.
ZHANG M., XIE B., Mak H.K.F. and Cheung R.T.F., Arterial stiffness and white matter hyperintensities in healthy hypertensive elderly Chinese, 18th Research Postgraduate Symposium. 2013, 5.26.


Researcher : Zhang Y

List of Research Outputs

Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.
LI X., Zhang Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Best Abstract - Mitochondrial Transfer Of Human Induced Pluripotent Stem Cells-derived Mesenchymal Stem Cells To Airway Epithelial Cells Attenuates Cigarette Smoke-induced Damage, ATS 2014 International Conference. 2014.
LI X., ZHANG Y., LIANG Y., Yeung S.C., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Mitochondrial transfer of human induced pluripotent stem cell-derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke-induced damage, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A5295.
LIANG Y., LI X., ZHANG Y., Ip M.S.M., Tse H.F., Lian Q. and Mak J.C.W., Attenuation of cigarette smoke-induced cardiac dysfunction and inflammation by mesenchymal stem cells in rat, American Thoracic Society International Conference 2014, Am J Respir Crit Care Med. 2014, 189: A6550.
Wu H., Yiu W.H., LI R., WONG W.L.D., Leung J.C.K., Chan Y.Y., Zhang Y., Lian Q., LIN M., Tse H.F., Lai K.N. and Tang S.C.W., Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis., PLoS One. 2014, 9 (3): e90883.
ZHANG Y., Yue J., CHE H., Sun H., Tse H.F. and Li G.R., BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells., J Cell Physiol. . 2013, 229(2): 202-212.
ZHANG Y., Li G., CHE H., Sun H., Li X., Au T.W.K., Xiao G.S., Wang Y. and Li G.R., Characterization of functional ion channels in human cardiac c-kit+ progenitor cells, Basic Res Cardiol. 2014, 109(3): 407.
ZHANG Y., WU H., CHE H., Sun H., Cheng L.C., Li X., Au T.W.K., Tse H.F. and Li G.R., Functional transient receptor potential canonical type 1 channels in human atrial myocytes, Pflügers Archiv - European Journal of Physiology. 2013, 465: 1439-1449.


Researcher : Zhao C

List of Research Outputs

Yiu K.H., Lau G.K.K., Zhao C., Chan Y.H., Chen Y., Zhen Z., Wong A., Lau C.P. and Tse H.F., Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus, Cardiovascular Diabetology. 2014, 13:63: 1-8.
Yiu K.H., Yeung C.K., Zhao C., Chan J.C., Siu D.C.W., Tam S., Wong C.S., Yan G.H., Yue W.S., Khong P.L., Cha H. and Tse H.F., Prevalence and extent of subclinical atherosclerosis in patients with psoriasis, J Intern Med. 2013, 3: 273-282.


Researcher : Zhen Z

List of Research Outputs

Yiu K.H., Lau G.K.K., Zhao C., Chan Y.H., Chen Y., Zhen Z., Wong A., Lau C.P. and Tse H.F., Predictive value of high-sensitivity troponin-I for future adverse cardiovascular outcome in stable patients with type 2 diabetes mellitus, Cardiovascular Diabetology. 2014, 13:63: 1-8.


Researcher : Zhou L

List of Research Outputs

Shea Y.F., Chu L.W., Zhou L., Li W.M., Lin O.Y., Chan M.N.Y., Xu A., Wong L.C., Ho T.Y. and Liu K.W., Cerebrospinal Fluid Biomarkers of Alzheimer's Disease in Chinese Patients: A Pilot Study, American Journal of Alzheimer's Disease and Other Dementias. 2013, 28: 769-775.


Researcher : Zhou M

List of Research Outputs

Hoo R.L.C., LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and translational (Oral Presentation), 19th Medical Research Conference. 2014.
LEE P.C., SHU L., Zhou M., Cheng K.Y., Lam K.S.L. and Xu A., Best Abstract in Basic Science and Translational (Oral Presentation), 19th Medical Research Conference. 2014.
Zhou M., PAN Y., SHU L., Lam K.S.L., Xu A. and Hoo R.L.C., Adipocyte fatty acid binding protein (A-FABP) is a potential mediator of diabetic cardiomyopathy and ischemic reperfusion induced cardiac injury , Ninth International Symposium on Healthy Aging “Aging with Confidence” . 2014.


Researcher : Zhu W

Project Title:Feedback effects of insulin on insulin release in pancreatic β-cells
Investigator(s):Zhu W, Lee HC
Department:Physiology
Source(s) of Funding:Small Project Funding
Start Date:04/2012
Completion Date:07/2013


List of Research Outputs

Cheng K.Y., Zhu W., CHEN B., Wang Y., Wu D., Sweeney G., WANG B., Lam K.S.L. and Xu A., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle, Diabetes. 2014, DB_140337: Epub ahead of print.


Researcher : Zuo M

List of Research Outputs

Zuo M., Yue W., Yip T., Ng F., Lam K.F., Yiu K.H., Lui S.L., Tse H.F., Siu D.C.W. and Lo W.K., Prevalence of and Associations With Reduced Exercise Capacity in Peritoneal Dialysis Patients, In: Andrew S. Levey, Daniel E. Weiner, American Journal of Kidney Diseases. Elsevier, 2013, 62: 939-946.


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