DEPT OF OBSTETRICS & GYNAECOLOGY



Researcher : CAI C

List of Research Outputs

Chan D.W., CAI C. and Ngan H.Y.S., Targeting TAK1/NF-κB signalling axis abrogates omental metastasis of ovarian cancer, COLD SPRING HARBOR ASIA CONFERENCES: Cell Signaling in Metabolism, Inflammation and Cancer. Suzhou Dushu Lake Conference Center September 2-26, 2013. Suzhou, Jiangsu Province, China. . Suzhou, Jiangsu Province, China., 2013.


Researcher : CAO M

List of Research Outputs

CAO M., Chan R.W.S. and Yeung W.S.B., Characterization of Mouse Endometrial Labeling Retaining Cells after Uterine Remodeling., 29th European Society of Human Reproduction and Embryology, London, United Kingdom, 1st – 3rd Jul 2013.. 2013.


Researcher : CHEN CH

List of Research Outputs

Lee C.Y.L., PENG Q., CHEN C.H., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 interacts with DNA repair molecules during the initiation phase of reprogramming from mouse fibroblasts to mouse induced pluripotent stem cells, ISSCR 12th Annual Meeting. 2014.


Researcher : CHEONG WYA

List of Research Outputs

CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation , Regional Best Abstract Award (Southeast Asia) - Society for the Study of Reproduction, USA. 2013.
CHEONG W.Y.A., Pang R.T.K., Liu W., KODITHUWAKKU KANKANAMGE S.P.K., Lee C.K.F. and Yeung W.S.B., MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos , Human Reproduction. 2014, 29: 750-762.
CHEONG W.Y.A., Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., Up-regulation of Lin28 and Dicer are required for the activation of mouse blastocysts. , SSR's 46th annual meeting reproductive health: Nano to Global, Montreal, Canada. 2013.


Researcher : CHEUNG TY

List of Research Outputs

TSANG H., CHEUNG T.Y., KODITHUWAKKU KANKANAMGE S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling, Reprod Toxicol. 2013, 42: 164-71.


Researcher : Chai J

Project Title:10th RCOG International Scientific Congress A randomized clinical trial comparing the sublingual and buccal routes of administration of misoprostol after mifepristone for medical abortions of up to 63 days gestation
Investigator(s):Chai J
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2012


Project Title:23th Asian and Oceanic Congress of Obstetrics and Gynecology; A pilot study on the combined use of letrozole, mifepristone and misoprostol in termination of first trimester pregnancy up to 9 weeks gestation
Investigator(s):Chai J
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


List of Research Outputs

Chai J. and Ng E.H.Y., Evidence-based investigations for subfertility , Journal of Paediatrics, Obstetric & Gynaecology. 2014, 40(3): 125-131.
Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience, Hong Kong Medical Journal. 2014.
Chai J., Lee C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, ESHRE annual meeting 2013.
Chai J. and Ho P.C., Medical abortion after 9 weeks, Abortion Care. 2014.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.
Lee V.C.Y., Li R.H.W., Chai J., Yeung T.W.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles, Fertility and Sterility. 2014, 101: 1288-1293.
TSANG H., CHEUNG T.Y., KODITHUWAKKU KANKANAMGE S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling, Reprod Toxicol. 2013, 42: 164-71.


Researcher : Chan DW

Project Title:The functional impact of AMP-activated protein kinase gamma-2 (AMPK-g2)subunit expression on AMPK activity and oncogenesis in ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2011


Project Title:Functional Characterization of Has-miR-141, a Putative Oncogene in Promoting Anchorage-Independent Growth Ability of Ovarian Cancer Cells
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012
Completion Date:02/2014


Project Title:Mechanistic and functional characterization of Bitter Melon extract (BME) and its active component, MAP30, in combating ovarian cancer chemoresistance
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013


Project Title:Cell Signaling in Metabolism, Inflammation and Cancer; Targeting TAK1/NF-kB signalling axis abrogates omental metastasis of ovarian cancer
Investigator(s):Chan DW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2013
Completion Date:09/2013


Project Title:Functional significance of TAK1-mediated NFkB signaling in omental metastasis of ovarian cancer
Investigator(s):Chan DW, Yam JWP, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


Project Title:Identification putative genetic or epigenetic candidate genes associated with omental metastasis of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2014


List of Research Outputs

Chan D.W., YUNG M.H. and Ngan H.Y.S., MAP30 protein of Momordica charantia functions as a natural AMPK activator in combating tumorigenic and chemoresistant capacities of ovarian cancer, Croucher Advanced Study Institute (ASI): Tumour Microenvironment – Cancer Cell Metabolism. LKS Faculty of Medicine, HKU. 13 November, 2013.. Croucher Advanced Study Institute (ASI), 2013.
Chan D.W. and Ngan H.Y.S., Targeting AMPK as a valid therapeutic intervention in ovarian cancer, International Workshop on Women's Reproductive Health Research. 2014.
Chan D.W., CAI C. and Ngan H.Y.S., Targeting TAK1/NF-κB signalling axis abrogates omental metastasis of ovarian cancer, COLD SPRING HARBOR ASIA CONFERENCES: Cell Signaling in Metabolism, Inflammation and Cancer. Suzhou Dushu Lake Conference Center September 2-26, 2013. Suzhou, Jiangsu Province, China. . Suzhou, Jiangsu Province, China., 2013.
Chan D.W., 有關於苦瓜的好處及醫藥價值, RTHK《緣來好食德》- 香港電台電視部, 2014.
Chan K.K.L., Leung T.H.Y., Chan D.W., WEI N., Lau T.Y., Liu S., Siu K.Y. and Ngan H.Y.S., Targeting estrogen receptor subtypes (ERalpha and ERbeta) with selective ER modulators in ovarian cancer, Journal of Endocrinology. Great Britain, Bioscientifica Ltd, 2014, 221: 325-336.
LI C., Liu V.W.S., Chiu P.M., Yao K.M., Ngan H.Y.S. and Chan D.W., Reduced expression of AMPK-beta1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer, In: Christophe Nicot, Molecular Cancer. United Kingdom, BioMed Central, 2014, 13: 49.
LIU X., Siu K.Y., Liu S., Yam J.W.P., Ngan H.Y.S. and Chan D.W., Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer., In: Andrei V. Gudkov and Mikhail V. Blagosklonny, Oncotarget. Impact Journals LLC, 2014, 5: 944–958.
Leung T.H.Y., WONG C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cells, British Journal of Cancer. 2013, 109: 965-975.
MAK S.L., Chan D.W. and Ngan H.Y.S., The upregulation of miR-141 confers anoikis resistance through targeting KLF12 in ovarian cancer cells, The 18th Research Postgraduate Symposium. LKS Faculty of Medicine, HKU. December 12-13th, 2013. LKS Faculty of Medicine, HKU.
Yao K.M., Lam A.K.Y., NGAN W.L., LEUNG M.H., KWOK C.T.D., Liu V.W.S., Chan D.W. and Leung W.Y.G., Differential Regulation of FOXM1 Isoforms by RAF/MEK/ERK Signaling, Gordon Research Conference: Posttranslational modification networks. 2013.
Yung M.H., Chan D.W., Liu V.W.S., Yao K.M. and Ngan H.Y.S., Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade, BMC Cancer. 2013, 13: 327.


Researcher : Chan KKL

Project Title:Relationship between placental ratio and placental function
Investigator(s):Chan KKL, Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding for New Staff
Start Date:01/2003


Project Title:The effect of fulvestrant in epithelial ovarian cancer with differential estrogen receptor status in mice
Investigator(s):Chan KKL, Liu S, Tam KF, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2008


Project Title:Sixth International Symposium on Hormonal Oncogenesis USE OF HIGHLY SELECTIVE ESTROGEN RECEPTOR MODULATORS IN OVARIAN CANCER
Investigator(s):Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2010


Project Title:Characterization of the Platelet Isoform of Phosphofructokinase (PFKP) in ovarian cancer
Investigator(s):Chan KKL, Siu KY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013


Project Title:Differential roles of estrogen receptor subtypes and variants in ovarian cancer: implications for personalized hormonal treatment.
Investigator(s):Chan KKL, Leung THY, Ngan HYS, Siu KY, Cheung ANY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


Project Title:Unraveling the role of pyruvate dehydrogenase kinase 1 (PDK1) in ovarian cancer chemoresistance
Investigator(s):Chan KKL, Ngan HYS, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2014


List of Research Outputs

Chan K.K.L., Editorial Board - Journal of Paediatrics, Obstetrics and Gynaecology. 2014.
Chan K.K.L., Leung T.H.Y., Chan D.W., WEI N., Lau T.Y., Liu S., Siu K.Y. and Ngan H.Y.S., Targeting estrogen receptor subtypes (ERalpha and ERbeta) with selective ER modulators in ovarian cancer, Journal of Endocrinology. Great Britain, Bioscientifica Ltd, 2014, 221: 325-336.
Kwan T.T.C., Chan K.K.L., Chu M.Y.M., Ho R.T.H., Chan C.L.W. and Ngan H.Y.S., Post-hysterectomy fatigue in women with malignant or benign gynaecologic diseases, The 20th Hong Kong International Cancer Congress (14-15 Nov, 2013). 2013.
Kwan T.T.C., Chan K.K.L., Chu M.Y.M., Ho R.T.H., Chan C.L.W. and Ngan H.Y.S., Post-hysterectomy fatigue in women with malignant or benign gynaecologic diseases, The 20th Hong Kong International Cancer Congress (14-15, November, 2013) Hong Kong. 2013.
Lee E.Y.P., Khong P.L., Tse K.Y., Chan K.K.L., Chu M.M.Y. and Ngan H.Y.S., Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value. , Nuclear Medicine Communications. 2013, 34: 1185-1189.
Lee E.Y.P., Khong P.L., Tse K.Y., Chan K.K.L., Chu M.Y.M. and Ngan H.Y.S., Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value, Nucl Med Commun. 2013, 34(12 ): 1185-1189.
Lee E.Y.P., Khong P.L., Tse K.Y., Chu M.Y., Chan K.K.L. and Ngan H.Y.S., SUVmax distinguishes the aggressive from the indolent subtypes of uterine sarcoma, International Cancer Imaging Society and 13th Annual Teaching Course. 2013.
Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Human papilloma virus E6 protein enhances CD55 expression on cervical cancer cell surface which promotes radio-resistance and cancer aggressiveness, The 2014 Controlling Cancer Summit, London, UK. 2014.
Leung T.H.Y., WONG C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cells, British Journal of Cancer. 2013, 109: 965-975.
Ngan H.Y.S. and Chan K.K.L., Gynaecological oncology, In: Ian Symonds, Sir Sabaratnam Arulkumaran, E Malcolm Symonds (Emeritus Editor), Essential Obstetrics Gynaecology, Churchill Livingstone 2013, Chapter 20, Fifth Edition. 2013, 317-339.
Ngu S.F. and Chan K.K.L., Management of Chemoresistant and Quiescent Gestational Trophoblastic Disease, Current Obstetrics and Gynecology Reports. 2014.
Siu K.Y., Wong E.S.Y., Kong S.H., Chan H.Y., JIANG L., Wong G.W., Chan K.K.L., Ngan H.Y.S., Le X.F. and Cheung A.N.Y., Stem Cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-Cadherin and Fox JI and contributes to adverse clinical outcome in ovarian cancers. 2013, 32(30): 3500-9.


Researcher : Chan RWS

Project Title:The Effect of Macrophages on Putative Stem/Progenitor Cells in Endometrium and Endometriosis.
Investigator(s):Chan RWS, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2013
Completion Date:08/2014


List of Research Outputs

CAO M., Chan R.W.S. and Yeung W.S.B., Characterization of Mouse Endometrial Labeling Retaining Cells after Uterine Remodeling., 29th European Society of Human Reproduction and Embryology, London, United Kingdom, 1st – 3rd Jul 2013.. 2013.
Chan R.W.S., Mak A.S., Yeung W.S.B., Lee C.K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S., Human female reproductive tract epithelial cell culture., Methods Mol Biol.. 2013, 945: 347-363.


Researcher : Chan YC

List of Research Outputs

Shek N.W.M., Ngai C.S.W., Lee C.P., Chan Y.C. and Lao T.T.H., Lifestyle modifications in the development of diabetes mellitus and metabolic syndrome in Chinese women who had gestational diabetes mellitus: a randomized interventional trial, Archives of Gynecology and Obstetrics . 2014, 289: 319-327.


Researcher : Chan YK

Project Title:Validating and examining SNPs identified from genome-wide scanning for disease susceptibility to HBV-related liver cancer in Chinese population
Investigator(s):Chan YK, Ng IOL, Wong CM
Department:Pathology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2010


List of Research Outputs

Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.
Lo I.F.M., Leung K.C., Luk H.M.M., Wong W.L., Tang L.Y.F., Chu Y.W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Chan Y.K. and Chung B.H.Y., Massive parallel sequencing for the genetic diagnosis of rasopathies – a study of 58 Chinese patients in Hong Kong. , Poster presentation in CCMG Annual Meeting, 2013.. 2013.
Luk H.M., Wong V.C.H., Lo I.F.M., Chan Y.K., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Tang W.F., She W.M.K., Chu W.Y., Sin W.K. and Chung B.H.Y., A prenatal case of split-hand malformation associated with 17p13.3 triplication – A dilemma in genetic counseling, European Journal of Medical Genetics. Elsevier, 2014, 57: 81-84.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
YEUNG K.S., Chee W.Y.Y., Luk H.M., Tang M.H.Y., Lau E.T.K., Shuen Y.A., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Evidence of spread of X chromosome inactivation on chromosome 15 in a girl with an unbalanced t(X;15) transolcation, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 64.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 36.


Researcher : Cheong AWY

List of Research Outputs

Cheong A.W.Y., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation. , The 46th Annual Meeting of SSR, 22–26 July 2013, Montréal, Québec, Canada.. 2013.


Researcher : Cheung KW

Project Title:A multi-center prospective study on the evaluation of paternal, maternal and obstetric factors leading to the hepatitis B immunization failure in Hong Kong
Investigator(s):Cheung KW, Seto TYM, Kan SYA, Ng EHY, Kou KOT, Lau WL, Wong RMS, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


List of Research Outputs

Cheung K.W., Shek N.W.M. and Chan K.H., An unusual cause of postpartum collapse:undiagnosed myasthenia gravis, Journal of Obstetrics and Gynecology . 2013, 33(5): 528.


Researcher : Cheung SYC

List of Research Outputs

Cheung S.Y.C., Chan C.H.Y. and Ng E.H.Y., Stress and anxiety-depression levels following first-trimester miscarriage: a comparison between women who conceived naturally and women who conceived with assisted reproduction, BJOG: An International Journal of Obstetrics & Gynaecology. 2013, 120(9): 1090-1097.


Researcher : Cheung VYT

List of Research Outputs

Cheung V.Y.T., Embedded stainless steel ring intrauterine device., J Fam Plann Reprod Health Care. 2013, 39(2): 153-154.
Cheung V.Y.T. and Ngu S.F., Diagnosis and Follow Up of Cesarean Scar Ectopic Pregnancies by Sonography, The 23rd Asian & Oceanic Congress of Obstetrics & Gynaecology, Bangkok, Thailand. 2013.
Cheung V.Y.T., Management of ovarian cysts complicating pregnancy., Symposium on Evidence-Based Practice in Obstetrics and Gynaecology, HKU-Shenzhen Hospital. 2013.. 2013.
Cheung V.Y.T., Sonographically guided high-intensity focused ultrasound for the management of uterine fibroids., Journal of Ultrasound In Medicine. 2013, 32(8): 1353-1358.
Cheung V.Y.T., Unusual ectopic pregnancies., Symposium on Evidence-Based Practice in Obstetrics and Gynaecology, HKU-Shenzhen Hospital. 2013.. 2013.
Ko K.Y.J., Seto T.Y.M., Ngu S.F. and Cheung V.Y.T., Urethral Prolapse in a postmenopausal woman, J Obstet Gynaecol Canada. 2014, 36(2): 105.
Lui M.W.E., Ngu S.F. and Cheung V.Y.T., Mullerian Cyst of the Uterus Misdiagnosed as Ovarian Cyst on Pelvic Sonography, J Clin Ultrasound. 2013.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Surgical Management of Adnexal Masses in Pregnancy, JSLS. 2014, 18(1): 71-75.
Ngu S.F., Ko K.Y.J. and Cheung V.Y.T., Value of human chorionic gonadotropin levels in diagnosing cervical ectopic pregnancy. , Acta Obstetricia et Gynecologica Scandinavica. 2013, 92(5): 608-609.


Researcher : Chiu CN

Project Title:The roles of protein disulfide isomerase family A, member 3 (ERp57) and surface thiol/disulfide exchange in spermatozoa-zona pellucida binding and their association with fertilization in vitro.
Investigator(s):Chiu CN, Pang RTK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Defective sialyl-Lewis(x) expression on human zona pellucida as a potential cause of subfertilty
Investigator(s):Chiu CN, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2012
Completion Date:05/2014


Project Title:Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction
Investigator(s):Chiu CN, Pang RTK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Biological properties of complex N-linked oligosaccharides of human oocytes
Investigator(s):Chiu CN, Yeung WSB, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Chiu C.N., WONG S.T., Lee C.L., Lam K.W., WONG H.H.V. and Yeung W.S.B., Control of human trophoblast functions by adrenomedullin, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Ko K.Y.J., HUANG W., Li R.H.W., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Chiu C.N., Ten best paper award: An in-vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions., Asian and Oceanic Congress of Obstetrics and Gynaecology, 20-23 October 2013, Bangkok, Thailand, . 2013.
Lee C.L., Li K., Lam K.W., Ng E.H.Y., Koistinen H., Seppala M., Yeung W.S.B. and Chiu C.N., Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility, Molecular reproduction and development. 2014, 81(6): 482-3.
Lee C.L., Chiu C.N., Hautala L., Salo T., Yeung W.S.B., Stenman U.H. and Koistinen H., Human chorionic gonadotropin and its free β-subunit stimulate trophoblast invasion independent of LH/hCG receptor., Molecular and Cellular Endocrinology. 2013, 375(1-2): 43-52.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.
WONG H.H.V., WAN H.L., CHAN Y.L. and Chiu C.N., Best Oral Presentation Award: Isolation of HLAG+CK7+ Trophoblastic Cells from Endocervix for Potential Use in Prenatal Genetic., The Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction, 24 November 2013, Hong Kong. . 2013.
WONG H.H.V., WAN H.L., CHAN Y.L. and Chiu C.N., Best Poster Presentation Award: Noninvasive Recovery of Endocervical Trophoblasts for Potential Use in Prenatal Genetic Diagnosis., The 18th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 11-12 December 2013, Hong Kong.. 2013.
Wong B.S., Lam K.K., Lee C.L., WONG H.H.V., Lam M.P., Chu I.K., Yeung W.S.B. and Chiu C.N., Adrenomedullin enhances invasion of human extravillous cytotrophoblast-derived cell lines by regulation of urokinase plasminogen activator expression and s-nitrosylation. (Feb 2013), Biology of Reproduction. 2013, 88(2): 34.
Yeung W.S.B., Lee C.K.F., Chiu C.N., Lee C.Y.L. and Pang R.T.K., Interactions between gametes/preimplantation embryos with the female reproductive tract, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014. 2014.


Researcher : Choi WK

List of Research Outputs

Zhong L., Tong Y., Tang G.W.K., Zhang Z., Choi W.K., Cheng K., Sze C.W., Wai K., Liu Q. and Yu X., A randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong perimenopausal women, Menopause . 2013, 20: 767-776.


Researcher : Chu MYM

List of Research Outputs

Kwan T.T.C., Chan K.K.L., Chu M.Y.M., Ho R.T.H., Chan C.L.W. and Ngan H.Y.S., Post-hysterectomy fatigue in women with malignant or benign gynaecologic diseases, The 20th Hong Kong International Cancer Congress (14-15 Nov, 2013). 2013.
Kwan T.T.C., Chan K.K.L., Chu M.Y.M., Ho R.T.H., Chan C.L.W. and Ngan H.Y.S., Post-hysterectomy fatigue in women with malignant or benign gynaecologic diseases, The 20th Hong Kong International Cancer Congress (14-15, November, 2013) Hong Kong. 2013.
Lee E.Y.P., Khong P.L., Tse K.Y., Chan K.K.L., Chu M.Y.M. and Ngan H.Y.S., Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value, Nucl Med Commun. 2013, 34(12 ): 1185-1189.


Researcher : Gao J

List of Research Outputs

Guo Y., Lee C.L., SO K.H., Gao J., Yeung W.S.B., Yao Y.Q. and Lee C.K.F., Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast invasion, PLoS One. 2013, 8: e76023.
Lee V.C.Y., Gao J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta, Hum Reprod. 2013, 28(11): 2912-9.


Researcher : Guo Y

List of Research Outputs

Guo Y., Lee C.L., SO K.H., Gao J., Yeung W.S.B., Yao Y.Q. and Lee C.K.F., Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast invasion, PLoS One. 2013, 8: e76023.
Lee C.L., Guo Y., Yao Y.Q., Yeung W.S.B. and Lee C.K.F., Soluble human leukocyte antigen-G5 stimulates trophoblast invasion via receptor-mediated activation of Extracellular Signal-regulated Protein Kinase Signaling. , P6. The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 24 Nov 2013, Hong Kong.. 2013.


Researcher : HUANG W

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Ko K.Y.J., HUANG W., Li R.H.W., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Chiu C.N., Ten best paper award: An in-vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions., Asian and Oceanic Congress of Obstetrics and Gynaecology, 20-23 October 2013, Bangkok, Thailand, . 2013.


Researcher : Ho PC

List of Research Outputs

Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience, Hong Kong Medical Journal. 2014.
Chai J., Lee C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, ESHRE annual meeting 2013.
Ho P.C., Director of Editorial Board in Obstetrics and Gynaecology, Journal of Paediatrics, Obstetrics and Gynaecology, 1997 till now. 2014.
Ho P.C., Member of Editorial Board, Chinese Journal of Obstetrics and Gynaecology. 2014.
Ho P.C., Member of Editorial Board, Clinical Obstetrics and Gynaecology (Bailliere Tindall). 2014.
Ho P.C., Member of Editorial Board, Journal of Practical Obstetrics and Gynaecology. 2014.
Ho P.C., Member of Editorial Board, Journal of Reproductive Medicine (China). 2014.
Ho P.C., Member of the Advisory Editorial Board, Asia Oceania Journal of Obstetrics and Gynaecology, 1994 till now. 2014.
Ho P.C., Reviewer for "American Journal of Obstetrics and Gynaecology". 2014.
Ho P.C., Reviewer for "Obstetrics and Gynaecology". 2014.
KWAN C.K., Pang R.T.K., LEUNG O.N., YE T., Yeung W.S.B. and Ho P.C., Effects of In-Vitro Culture And Bisphenol A Exposure On DNA Methylation Of Imprinted Genes May Be Obtainable In High Resolution From A Single Mouse Embryo, Society for the Study of Reproduction 2013: 46th General Meeting Reproductive Health: Nano to Global. 2013.
Ko K.Y.J., HUANG W., Li R.H.W., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Chiu C.N., Ten best paper award: An in-vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions., Asian and Oceanic Congress of Obstetrics and Gynaecology, 20-23 October 2013, Bangkok, Thailand, . 2013.
LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Poster Award (Title of poster presentation: In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model), 13th Congress of the European Society of Contraception and Reproductive Health. 2014.
Lee C.K.F., LIU Y., KODITHUWAKKU KANKANAMGE S.P.K., Ng E.H.Y. and Ho P.C., Ovarian Stimulation modulates human Endometrial Gene expression and Receptivity, The 8th International Huaxia Congress of Endocrinology, 21-22 August 2013, Xi’an, China. (Plenary Lecture CPL-03). 2013.
Lee V.C.Y., Li R.H.W., Chai J., Yeung T.W.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles, Fertility and Sterility. 2014, 101: 1288-1293.
Lee V.C.Y., Gao J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta, Hum Reprod. 2013, 28(11): 2912-9.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 205-211.
Li R.H.W., LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model, The 13th European Society of Contraception Congress. 2014.
Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is a better measure of ovarian responsiveness to gonadotrophin stimulation than the number of oocytes during in-vitro fertilization treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 199-203.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is an excellent measure of ovarian responsiveness to gonadotrophin stimulation in in-vitro fertilization, The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology. 2013.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Serum Level of Sex Hormone-Binding Globulin Is a Good Independent Predictor of Metabolic Syndrome in Women with Polycystic Ovary Syndrome, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo. 2014.


Researcher : Hui PW

Project Title:31st British International Congress of Obstetrics & Gynaecology 2007 A rare cause of Thrombocytopenia in Pregnancy-EDTA-dependent Pseudothrombocytopenia
Investigator(s):Hui PW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2007




Researcher : KODITHUWAKKU KANKANAMGE SPK

List of Research Outputs

CHEONG W.Y.A., Pang R.T.K., Liu W., KODITHUWAKKU KANKANAMGE S.P.K., Lee C.K.F. and Yeung W.S.B., MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos , Human Reproduction. 2014, 29: 750-762.
Lee C.K.F., LIU Y., KODITHUWAKKU KANKANAMGE S.P.K., Ng E.H.Y. and Ho P.C., Ovarian Stimulation modulates human Endometrial Gene expression and Receptivity, The 8th International Huaxia Congress of Endocrinology, 21-22 August 2013, Xi’an, China. (Plenary Lecture CPL-03). 2013.
TSANG H., CHEUNG T.Y., KODITHUWAKKU KANKANAMGE S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling, Reprod Toxicol. 2013, 42: 164-71.


Researcher : KOTTAWATTA KSA

List of Research Outputs

KOTTAWATTA K.S.A., SO K.H., Yeung W.S.B. and Lee C.K.F., Modulation of OLFM1 and CTBP1 Expression via miR-132/-212 in Human Endometrial Epithelial Cells. P2.16. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong.. 2013.


Researcher : KWAN CK

List of Research Outputs

KWAN C.K., Pang R.T.K., LEUNG O.N., YE T., Yeung W.S.B. and Ho P.C., Effects of In-Vitro Culture And Bisphenol A Exposure On DNA Methylation Of Imprinted Genes May Be Obtainable In High Resolution From A Single Mouse Embryo, Society for the Study of Reproduction 2013: 46th General Meeting Reproductive Health: Nano to Global. 2013.


Researcher : Kan SYA

List of Research Outputs

Chan S.H.S., Kan S.Y.A. and Tse H.K., An X-linked dominant mutation in LAMP2 causing Danon disease associated with myotonia expanding the spectrum, 18th International congress of the World Muscle Society. October 1st to 6th 2013. (Poster presentation). Neuromuscul Disord. 2013;23(9-10):821 [Abstract] . 2013, 23(9-10): 821.
Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.
Ko K.O., Lee H.H., Lau B., Wong W.S., Kan S.Y.A., Tang M.H.Y., Poon C.F. and Leung K.Y., Two unusual cases of haemoglobin Bart’s hydrops fetalis screened negative on universal prenatal screening for thalassaemia. , Poster presentation in ISUOG World Congress, 2013.. 2013.
Kou K.O.T., Lee H., Lau B., Wong W.S., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Poon C.F. and Leung K.Y., Two unusual cases of haemoglobin Bart’s hydrops fetalis due to uniparental disomy or non-paternity., Fetal Diagnosis and Therapy. 2013, 14: 14.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.
Lo I.F.M., Leung K.C., Luk H.M.M., Wong W.L., Tang L.Y.F., Chu Y.W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Chan Y.K. and Chung B.H.Y., Massive parallel sequencing for the genetic diagnosis of rasopathies – a study of 58 Chinese patients in Hong Kong. , Poster presentation in CCMG Annual Meeting, 2013.. 2013.
Luk H.M., Wong V.C.H., Lo I.F.M., Chan Y.K., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Tang W.F., She W.M.K., Chu W.Y., Sin W.K. and Chung B.H.Y., A prenatal case of split-hand malformation associated with 17p13.3 triplication – A dilemma in genetic counseling, European Journal of Medical Genetics. Elsevier, 2014, 57: 81-84.
Mok Y.K.S. and Kan S.Y.A., A community health programme to increase women’s awareness of osteoporosis in Hong Kong. , Poster presentation in IOF Regionals – 4th Asia-Pacific Osteoporosis Meeting, 2013.. 2013.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
Tao Q.V., She W., Chu W.Y., Tso W.Y.W., Chan K.Y., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 23.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 36.
Zayts O.A., Sarangi S., Thong M.K., Chung B.H.Y., Lo F.M., Kan S.Y.A., Lee M.H., Padilla C.D., Cutiongco-de la Paz E.M., Faradz M.H.S. and Wasant P., Genetic counseling/consultation in South-East Asia: A report from the workshop at the 10th Asia Pacific Conference on Human Genetics, Journal of Genetic Counseling . 2013, 22 (6): 917-924.


Researcher : Ko KYJ

List of Research Outputs

Ko K.Y.J., HUANG W., Li R.H.W., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Chiu C.N., Ten best paper award: An in-vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions., Asian and Oceanic Congress of Obstetrics and Gynaecology, 20-23 October 2013, Bangkok, Thailand, . 2013.
Ko K.Y.J., Seto T.Y.M., Ngu S.F. and Cheung V.Y.T., Urethral Prolapse in a postmenopausal woman, J Obstet Gynaecol Canada. 2014, 36(2): 105.
Ngu S.F., Ko K.Y.J. and Cheung V.Y.T., Value of human chorionic gonadotropin levels in diagnosing cervical ectopic pregnancy. , Acta Obstetricia et Gynecologica Scandinavica. 2013, 92(5): 608-609.


Researcher : Kou KOT

List of Research Outputs

Kou K.O.T., Lee H., Lau B., Wong W.S., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Poon C.F. and Leung K.Y., Two unusual cases of haemoglobin Bart’s hydrops fetalis due to uniparental disomy or non-paternity., Fetal Diagnosis and Therapy. 2013, 14: 14.


Researcher : LAM KW

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Chiu C.N., WONG S.T., Lee C.L., Lam K.W., WONG H.H.V. and Yeung W.S.B., Control of human trophoblast functions by adrenomedullin, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Lee C.L., Li K., Lam K.W., Ng E.H.Y., Koistinen H., Seppala M., Yeung W.S.B. and Chiu C.N., Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility, Molecular reproduction and development. 2014, 81(6): 482-3.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.


Researcher : LEUNG ON

List of Research Outputs

KWAN C.K., Pang R.T.K., LEUNG O.N., YE T., Yeung W.S.B. and Ho P.C., Effects of In-Vitro Culture And Bisphenol A Exposure On DNA Methylation Of Imprinted Genes May Be Obtainable In High Resolution From A Single Mouse Embryo, Society for the Study of Reproduction 2013: 46th General Meeting Reproductive Health: Nano to Global. 2013.
LEUNG O.N., Deng W., Ye T., Ngan H.Y.S., Tsao G.S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.
Pang R.T.K., LEUNG O.N., YE T., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., CERVICAL CANCER CD133 POSITIVE CELLS POSSESS TUMOR INITIATING CELLS PROPERTIES, 18th International Meeting of the European Society of Gynaecological Oncology (ESGO). International Journal of Gynecological Cancer, 2013.


Researcher : LI C

List of Research Outputs

LI C., Liu V.W.S., Chiu P.M., Yao K.M., Ngan H.Y.S. and Chan D.W., Reduced expression of AMPK-beta1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer, In: Christophe Nicot, Molecular Cancer. United Kingdom, BioMed Central, 2014, 13: 49.


Researcher : LI T

List of Research Outputs

LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Poster Award (Title of poster presentation: In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model), 13th Congress of the European Society of Contraception and Reproductive Health. 2014.
Li R.H.W., LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model, The 13th European Society of Contraception Congress. 2014.


Researcher : LI Y

List of Research Outputs

LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Poster Award (Title of poster presentation: In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model), 13th Congress of the European Society of Contraception and Reproductive Health. 2014.
Li R.H.W., LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model, The 13th European Society of Contraception Congress. 2014.


Researcher : LIU X

List of Research Outputs

LIU X., Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer., Oncotarget. 2014, 28.
LIU X., Siu K.Y., Liu S., Yam J.W.P., Ngan H.Y.S. and Chan D.W., Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer., In: Andrei V. Gudkov and Mikhail V. Blagosklonny, Oncotarget. Impact Journals LLC, 2014, 5: 944–958.


Researcher : LIU Y

List of Research Outputs

Lee C.K.F., LIU Y., KODITHUWAKKU KANKANAMGE S.P.K., Ng E.H.Y. and Ho P.C., Ovarian Stimulation modulates human Endometrial Gene expression and Receptivity, The 8th International Huaxia Congress of Endocrinology, 21-22 August 2013, Xi’an, China. (Plenary Lecture CPL-03). 2013.


Researcher : Lam KW

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Chiu C.N., WONG S.T., Lee C.L., Lam K.W., WONG H.H.V. and Yeung W.S.B., Control of human trophoblast functions by adrenomedullin, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Lee C.L., Li K., Lam K.W., Ng E.H.Y., Koistinen H., Seppala M., Yeung W.S.B. and Chiu C.N., Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility, Molecular reproduction and development. 2014, 81(6): 482-3.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.


Researcher : Lam KW

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Chiu C.N., WONG S.T., Lee C.L., Lam K.W., WONG H.H.V. and Yeung W.S.B., Control of human trophoblast functions by adrenomedullin, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Lee C.L., Li K., Lam K.W., Ng E.H.Y., Koistinen H., Seppala M., Yeung W.S.B. and Chiu C.N., Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility, Molecular reproduction and development. 2014, 81(6): 482-3.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.


Researcher : Lam SK

List of Research Outputs

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal Anxiety at the Second Trimester: Risk Factors and Effects on Anxiety and Infant Development at 6-Week Postpartum , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.
Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal anxiety in the first trimester: Risk factors and effects on anxiety and depression in the third trimester and 6-week postpartum, Open Journal of Psychiatry. 2013, 3: 301-310.
Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Anxiety during Pregnancy: Prevalence and Its Relations to Postpartum Anxiety , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.
Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Depression across Pregnancy: Prevalence, Pattern and Relations to Postpartum Depression, Depression Research and Treatment 2014. 2014.
Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal anxiety across pregnancy: Prevalence, pattern and relations to postpartum anxiety, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden Connecting Research in Clinical Practice, Melbourne, Australia, October 21, 2013.


Researcher : Lam YH

Project Title:11th World Congress on Ultrasound in Obstetrics and Gynecology Integrated First and Second Trimester Screening for Down Syndrome
Investigator(s):Lam YH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2001




Researcher : Lao TTH

Project Title:The First Congress on Obstetrics, Gynecology & Infertility Does Impaired Glucose Tolerance Impact on Pregnancy Outcome?
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/1999


Project Title:Dietary caloric intake and the development of gestational diabetes mellitus in at-risk Chinese women
Investigator(s):Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:Elevated TNF-α in gestational diabetes mellitus-cause or consequence?
Investigator(s):Lao TTH, Leung WC, Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The relationship between the antioxidant defense system with the development of gestational diabetes mellitus and its complications in the Chinese population.
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2005




Researcher : Lau ETK

List of Research Outputs

Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.
Kou K.O.T., Lee H., Lau B., Wong W.S., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Poon C.F. and Leung K.Y., Two unusual cases of haemoglobin Bart’s hydrops fetalis due to uniparental disomy or non-paternity., Fetal Diagnosis and Therapy. 2013, 14: 14.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Luk H.M., Wong V.C.H., Lo I.F.M., Chan Y.K., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Tang W.F., She W.M.K., Chu W.Y., Sin W.K. and Chung B.H.Y., A prenatal case of split-hand malformation associated with 17p13.3 triplication – A dilemma in genetic counseling, European Journal of Medical Genetics. Elsevier, 2014, 57: 81-84.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
Tao Q.V., She W., Chu W.Y., Tso W.Y.W., Chan K.Y., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 23.
YEUNG K.S., Chee W.Y.Y., Luk H.M., Tang M.H.Y., Lau E.T.K., Shuen Y.A., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Evidence of spread of X chromosome inactivation on chromosome 15 in a girl with an unbalanced t(X;15) transolcation, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 64.


Researcher : Lau EYL

List of Research Outputs

Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience, Hong Kong Medical Journal. 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 205-211.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is an excellent measure of ovarian responsiveness to gonadotrophin stimulation in in-vitro fertilization, The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology. 2013.


Researcher : Lau TY

List of Research Outputs

Chan K.K.L., Leung T.H.Y., Chan D.W., WEI N., Lau T.Y., Liu S., Siu K.Y. and Ngan H.Y.S., Targeting estrogen receptor subtypes (ERalpha and ERbeta) with selective ER modulators in ovarian cancer, Journal of Endocrinology. Great Britain, Bioscientifica Ltd, 2014, 221: 325-336.


Researcher : Lee CKF

Project Title:Functional characterization of VAD1.3, a novel acrosome-specific protein by conditional tissue-specific gene inactivation
Investigator(s):Lee CKF, Cheah KSE, Yeung WSB, Luk JMC, Lee NPY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006


Project Title:Environmental Screening, Computational and Biological Characterization of Endocrine Disruptors, in Respect to Receptor Binding, Embryo and Gonad Physiology
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2009


Project Title:Study of Electroacupuncture on modulating rodent spermatogenesis after scrotal heat treatment
Investigator(s):Lee CKF, Yeung WSB, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2012
Completion Date:10/2013


Project Title:Functional roles of human chorionic gonadotropin (hCG) and Wnt-signaling molecules on tubal ectopic pregnancy
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:Embryo-Female Reproductive Tract Interaction: A study on the role of embryo-derived factor(s) on endometrial receptivity through microRNA regulation
Investigator(s):Lee CKF, Ng EHY, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:International Workshop on Women’s Reproductive Health Research; Roles of Human Chorionic Gonadotrophin on embryo attachment onto Fallopian tube
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2014
Completion Date:04/2014


Project Title:Mechanistic actions of embryotrophic factor iC3b on in vitro embryo development
Investigator(s):Lee CKF, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2014


List of Research Outputs

CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation , Regional Best Abstract Award (Southeast Asia) - Society for the Study of Reproduction, USA. 2013.
CHEONG W.Y.A., Pang R.T.K., Liu W., KODITHUWAKKU KANKANAMGE S.P.K., Lee C.K.F. and Yeung W.S.B., MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos , Human Reproduction. 2014, 29: 750-762.
CHEONG W.Y.A., Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., Up-regulation of Lin28 and Dicer are required for the activation of mouse blastocysts. , SSR's 46th annual meeting reproductive health: Nano to Global, Montreal, Canada. 2013.
Chan R.W.S., Mak A.S., Yeung W.S.B., Lee C.K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S., Human female reproductive tract epithelial cell culture., Methods Mol Biol.. 2013, 945: 347-363.
Cheong A.W.Y., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation. , The 46th Annual Meeting of SSR, 22–26 July 2013, Montréal, Québec, Canada.. 2013.
Guo Y., Lee C.L., SO K.H., Gao J., Yeung W.S.B., Yao Y.Q. and Lee C.K.F., Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast invasion, PLoS One. 2013, 8: e76023.
Horne A.W., Brown J.K., Nio-Kobayashi J., Abidin H.B., Adin Z.E., Boswell L., Burgess S., Lee C.K.F. and Duncan W.C., The Association between Smoking and Ectopic Pregnancy: Why Nicotine Is BAD for Your Fallopian Tube. , PLoS One. 2014, 9(2): e89400.
KOTTAWATTA K.S.A., SO K.H., Yeung W.S.B. and Lee C.K.F., Modulation of OLFM1 and CTBP1 Expression via miR-132/-212 in Human Endometrial Epithelial Cells. P2.16. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong.. 2013.
LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Poster Award (Title of poster presentation: In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model), 13th Congress of the European Society of Contraception and Reproductive Health. 2014.
Lee C.K.F., LIU Y., KODITHUWAKKU KANKANAMGE S.P.K., Ng E.H.Y. and Ho P.C., Ovarian Stimulation modulates human Endometrial Gene expression and Receptivity, The 8th International Huaxia Congress of Endocrinology, 21-22 August 2013, Xi’an, China. (Plenary Lecture CPL-03). 2013.
Lee C.L., Guo Y., Yao Y.Q., Yeung W.S.B. and Lee C.K.F., Soluble human leukocyte antigen-G5 stimulates trophoblast invasion via receptor-mediated activation of Extracellular Signal-regulated Protein Kinase Signaling. , P6. The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 24 Nov 2013, Hong Kong.. 2013.
Lee V.C.Y., Gao J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta, Hum Reprod. 2013, 28(11): 2912-9.
Li R.H.W., LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model, The 13th European Society of Contraception Congress. 2014.
Li T.K.T., Li R.H.W., Yeung T.W.Y., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The Endocrine Disruptor Perflurooctane sulfonate (PFOS) modulates Spheroids attachment onto Endometrial cells through Wnt/-catenin inhibition. P2.21. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong. . 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Human chorionic gonadotropin enhances receptivity of Fallopian tube through down-regulation of Olfactomedin-1., The 46th Annual Meeting of SSR, 22–26 July, 2013, Montréal, Québec, Canada.. 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast onto endometrial epithelial cells through activation of ERK and Wnt/beta-catenin signaling pathway. , The 8th International Huaxia Congress of Endocrinology, 21-22 August, 2013, Xi’an, China.. 2013.
So K.H., Lee C.Y.L., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast surrogate onto endometrial/Oviductal epithelial cell monolayer through activation of ERK and Wnt/beta-catenin signaling pathway. OP3., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 24 November, 2013, Hong Kong.. 2013.
TSANG H., CHEUNG T.Y., KODITHUWAKKU KANKANAMGE S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling, Reprod Toxicol. 2013, 42: 164-71.
YEUNG A.S.-.Y., So K.H., Yeung W.S.B. and Lee C.K.F., Generation of Trs4 knockout mice for spermatogenesis studies. P1.29., The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 December, 2013, Hong Kong.. 2013.
Yeung W.S.B., Lee C.K.F., Chiu C.N., Lee C.Y.L. and Pang R.T.K., Interactions between gametes/preimplantation embryos with the female reproductive tract, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014. 2014.
ZHANG L., CHEUNG H.P., Lee C.K.F., Ng T.B., Zhang Y., Lao L. and Sze C.W., Proteomics Analysis of the Ovarian Tissues of Sprague-Dawley Rats of Different Ages to Identify Aging-Associated Changes, Ninth International Symposium on Healthy Aging “Aging with Confidence”, Hong Kong. 2014.


Researcher : Lee CL

Project Title:The role of soluble human leukocyte antigen G5 on decidual macrophage differentiation
Investigator(s):Lee CL, Yeung WSB, Chiu CN, Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Chiu C.N., WONG S.T., Lee C.L., Lam K.W., WONG H.H.V. and Yeung W.S.B., Control of human trophoblast functions by adrenomedullin, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Guo Y., Lee C.L., SO K.H., Gao J., Yeung W.S.B., Yao Y.Q. and Lee C.K.F., Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast invasion, PLoS One. 2013, 8: e76023.
Lee C.L., Li K., Lam K.W., Ng E.H.Y., Koistinen H., Seppala M., Yeung W.S.B. and Chiu C.N., Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility, Molecular reproduction and development. 2014, 81(6): 482-3.
Lee C.L., Chiu C.N., Hautala L., Salo T., Yeung W.S.B., Stenman U.H. and Koistinen H., Human chorionic gonadotropin and its free β-subunit stimulate trophoblast invasion independent of LH/hCG receptor., Molecular and Cellular Endocrinology. 2013, 375(1-2): 43-52.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.
Lee C.L., Guo Y., Yao Y.Q., Yeung W.S.B. and Lee C.K.F., Soluble human leukocyte antigen-G5 stimulates trophoblast invasion via receptor-mediated activation of Extracellular Signal-regulated Protein Kinase Signaling. , P6. The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 24 Nov 2013, Hong Kong.. 2013.
Wong B.S., Lam K.K., Lee C.L., WONG H.H.V., Lam M.P., Chu I.K., Yeung W.S.B. and Chiu C.N., Adrenomedullin enhances invasion of human extravillous cytotrophoblast-derived cell lines by regulation of urokinase plasminogen activator expression and s-nitrosylation. (Feb 2013), Biology of Reproduction. 2013, 88(2): 34.


Researcher : Lee CP

List of Research Outputs

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal Anxiety at the Second Trimester: Risk Factors and Effects on Anxiety and Infant Development at 6-Week Postpartum , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.
Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal anxiety in the first trimester: Risk factors and effects on anxiety and depression in the third trimester and 6-week postpartum, Open Journal of Psychiatry. 2013, 3: 301-310.
Cheung C.S., Li T.K.T. and Lee C.P., Maternal atrial fibrillation after sequential use of nifedipine and atosiban for treatment of preterm labor: case report, 2013 Feb , European Journal of Obstetrics and Gynecology and Reproductive Biology. 2013, 166(2): 299.
Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.
Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Anxiety during Pregnancy: Prevalence and Its Relations to Postpartum Anxiety , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.
Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Depression across Pregnancy: Prevalence, Pattern and Relations to Postpartum Depression, Depression Research and Treatment 2014. 2014.
Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal anxiety across pregnancy: Prevalence, pattern and relations to postpartum anxiety, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden Connecting Research in Clinical Practice, Melbourne, Australia, October 21, 2013.
Lee C.P., Gestational Diabetes, Symposium on endocrine disorders in pregnancy, HKU-Shenzhen Hospital. 2014.
Lee C.P., Gestational Diabetes, Update of Diabetes Management 2013, KK Leung Diabetes, Centre, Queen Mary Hospital and Research Centre of Heart, Brain, Hormone and Healthy Aging , the University of Hong Kong. 2013.
Lee C.P., Management of Pre-eclampsia, Symposium on Evidence-Based Practice in Obstetrics and Gynaecology, HKU-Shenzhen Hospital. 2013.
Shek N.W.M., Ngai C.S.W., Lee C.P., Chan Y.C. and Lao T.T.H., Lifestyle modifications in the development of diabetes mellitus and metabolic syndrome in Chinese women who had gestational diabetes mellitus: a randomized interventional trial, Archives of Gynecology and Obstetrics . 2014, 289: 319-327.


Researcher : Lee CYL

List of Research Outputs

KWOK C.T.D., LEUNG M.H., Lee C.Y.L. and Yao K.M., Investigating the role of FOXM1 in the maintenance of human embryonic stem cell pluripotency, 12th Annual Meeting of the International Society for Stem Cell Research, Vancouver, Canada, June 18-21, 2014.
LEUNG M.H., KWOK C.T.D., Lee C.Y.L. and Yao K.M., Investigating the protective role of FOXM1 against oxidative stress and DNA damage in human embryonic stem cells, 12th Annual Meeting of the International Society for Stem Cell Research, Vancouver, Canada, June 18-21, 2014.
Lee C.Y.L., PENG Q., CHEN C.H., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 interacts with DNA repair molecules during the initiation phase of reprogramming from mouse fibroblasts to mouse induced pluripotent stem cells, ISSCR 12th Annual Meeting. 2014.
So K.H., Lee C.Y.L., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast surrogate onto endometrial/Oviductal epithelial cell monolayer through activation of ERK and Wnt/beta-catenin signaling pathway. OP3., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 24 November, 2013, Hong Kong.. 2013.
Yeung W.S.B., Lee C.K.F., Chiu C.N., Lee C.Y.L. and Pang R.T.K., Interactions between gametes/preimplantation embryos with the female reproductive tract, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014. 2014.


Researcher : Lee VCY

List of Research Outputs

Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience, Hong Kong Medical Journal. 2014.
Lee V.C.Y., Li R.H.W., Chai J., Yeung T.W.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles, Fertility and Sterility. 2014, 101: 1288-1293.
Lee V.C.Y., Gao J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta, Hum Reprod. 2013, 28(11): 2912-9.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 205-211.
Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is a better measure of ovarian responsiveness to gonadotrophin stimulation than the number of oocytes during in-vitro fertilization treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 199-203.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is an excellent measure of ovarian responsiveness to gonadotrophin stimulation in in-vitro fertilization, The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology. 2013.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Serum Level of Sex Hormone-Binding Globulin Is a Good Independent Predictor of Metabolic Syndrome in Women with Polycystic Ovary Syndrome, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo. 2014.


Researcher : Leung KC

List of Research Outputs

Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.
Lo I.F.M., Leung K.C., Luk H.M.M., Wong W.L., Tang L.Y.F., Chu Y.W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Chan Y.K. and Chung B.H.Y., Massive parallel sequencing for the genetic diagnosis of rasopathies – a study of 58 Chinese patients in Hong Kong. , Poster presentation in CCMG Annual Meeting, 2013.. 2013.


Researcher : Leung KY

List of Research Outputs

Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.
Ko K.O., Lee H.H., Lau B., Wong W.S., Kan S.Y.A., Tang M.H.Y., Poon C.F. and Leung K.Y., Two unusual cases of haemoglobin Bart’s hydrops fetalis screened negative on universal prenatal screening for thalassaemia. , Poster presentation in ISUOG World Congress, 2013.. 2013.
Kou K.O.T., Lee H., Lau B., Wong W.S., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Poon C.F. and Leung K.Y., Two unusual cases of haemoglobin Bart’s hydrops fetalis due to uniparental disomy or non-paternity., Fetal Diagnosis and Therapy. 2013, 14: 14.
Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Depression across Pregnancy: Prevalence, Pattern and Relations to Postpartum Depression, Depression Research and Treatment 2014. 2014.
Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal anxiety across pregnancy: Prevalence, pattern and relations to postpartum anxiety, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden Connecting Research in Clinical Practice, Melbourne, Australia, October 21, 2013.


Researcher : Leung THY

Project Title:Clinical correlation of DNp73/C35/HER2 and their cooperative effects in ovarian cancer.
Investigator(s):Leung THY, Ngan HYS, Cheung ANY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:The 2014 Controlling Cancer Summit ; Human Papilloma Virus E6 protein enhances CD55 expression on cervical cancer cell surface which promotes radio-resistance and cancer aggressiveness
Investigator(s):Leung THY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2014
Completion Date:05/2014


List of Research Outputs

Chan K.K.L., Leung T.H.Y., Chan D.W., WEI N., Lau T.Y., Liu S., Siu K.Y. and Ngan H.Y.S., Targeting estrogen receptor subtypes (ERalpha and ERbeta) with selective ER modulators in ovarian cancer, Journal of Endocrinology. Great Britain, Bioscientifica Ltd, 2014, 221: 325-336.
Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Human papilloma virus E6 protein enhances CD55 expression on cervical cancer cell surface which promotes radio-resistance and cancer aggressiveness, The 2014 Controlling Cancer Summit, London, UK. 2014.
Leung T.H.Y., WONG C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cells, British Journal of Cancer. 2013, 109: 965-975.


Researcher : Leung WC

List of Research Outputs

Chan E.K.L., Yan E.C.W., Fong D.Y.T., Tiwari A.F.Y. and Leung W.C., Child Sexual Abuse and Health Outcomes in the Chinese Context, International Psychiatry. 2013, 10: 81-83.
Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.


Researcher : Li RHW

Project Title:An in vitro study of endocrine factors regulating expression of anti-Mullerian hormone in human granulosa cells
Investigator(s):Li RHW, Yeung WSB, Cheung ANY, Ng EHY, Ho PC, O WS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2013


Project Title:13th Congress of the European Society of Contraception and Reproductive Health; In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model
Investigator(s):Li RHW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2014


Project Title:A randomised trial to compare antral follicle count and serum anti-Mullerian hormone level for determination of gonadotrophin dosing in in-vitro fertilisation
Investigator(s):Li RHW, Lee VCY, Yeung TWY, Chai J, Lau EYL, Yeung WSB, Ho PC, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience, Hong Kong Medical Journal. 2014.
Chai J., Lee C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, ESHRE annual meeting 2013.
Ko K.Y.J., HUANG W., Li R.H.W., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Chiu C.N., Ten best paper award: An in-vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions., Asian and Oceanic Congress of Obstetrics and Gynaecology, 20-23 October 2013, Bangkok, Thailand, . 2013.
Lee V.C.Y., Li R.H.W., Chai J., Yeung T.W.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles, Fertility and Sterility. 2014, 101: 1288-1293.
Li R.H.W., Antimullerian hormone in reproductive medicine, The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology. Bangkok, 2013.
Li R.H.W., Contraception in the obese women, 5th Congress of Asia Pacific Council on Contraception. Kuala Lumpur, 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 205-211.
Li R.H.W., Emergency contraception, 4th Annual Scientific Meeting, Obstetrical and Gynaecological Society of Hong Kong. Hong Kong, 2014.
Li R.H.W., Extending the golden life of women: management of the menopause, Ninth International Symposium on Healthy Aging. Hong Kong, 2014.
Li R.H.W., LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model, The 13th European Society of Contraception Congress. 2014.
Li R.H.W., Management of anovulatory infertility, The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology. Bangkok, 2013.
Li R.H.W., Management of polycystic ovary syndrome, Symposium on Evidence-Based Practice in Obstetrics and Gynaecology. Shenzhen, 2013.
Li R.H.W., New developments in oral hormonal contraception, Postgraduate Seminar, Hong Kong College of Obstetricians and Gynaecologists. Hong Kong, 2013.
Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is a better measure of ovarian responsiveness to gonadotrophin stimulation than the number of oocytes during in-vitro fertilization treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 199-203.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is an excellent measure of ovarian responsiveness to gonadotrophin stimulation in in-vitro fertilization, The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology. 2013.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Serum Level of Sex Hormone-Binding Globulin Is a Good Independent Predictor of Metabolic Syndrome in Women with Polycystic Ovary Syndrome, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo. 2014.
Li R.H.W., AMH 在生殖醫學中的應用, 全國生殖内分泌与辅助生殖技术研修班, Shenzhen, 2013.
Li T.K.T., Li R.H.W., Yeung T.W.Y., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The Endocrine Disruptor Perflurooctane sulfonate (PFOS) modulates Spheroids attachment onto Endometrial cells through Wnt/-catenin inhibition. P2.21. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong. . 2013.
Lui M.W.E., Shek N.W.M., Li R.H.W., Chu S.K.F. and Pun T.C., Management of heterotopic cesarean scar pregnancy by repeated transvaginal ultrasonographic-guided aspiration with successful preservation of normal intrauterine pregnancy and complicated by arteriovenous malformation, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2014, 175: 209-210.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100: 459-463.e1.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Human chorionic gonadotropin enhances receptivity of Fallopian tube through down-regulation of Olfactomedin-1., The 46th Annual Meeting of SSR, 22–26 July, 2013, Montréal, Québec, Canada.. 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast onto endometrial epithelial cells through activation of ERK and Wnt/beta-catenin signaling pathway. , The 8th International Huaxia Congress of Endocrinology, 21-22 August, 2013, Xi’an, China.. 2013.
So K.H., Lee C.Y.L., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast surrogate onto endometrial/Oviductal epithelial cell monolayer through activation of ERK and Wnt/beta-catenin signaling pathway. OP3., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 24 November, 2013, Hong Kong.. 2013.


Researcher : Li TKT

List of Research Outputs

Cheung C.S., Li T.K.T. and Lee C.P., Maternal atrial fibrillation after sequential use of nifedipine and atosiban for treatment of preterm labor: case report, 2013 Feb , European Journal of Obstetrics and Gynecology and Reproductive Biology. 2013, 166(2): 299.
Li T.K.T., Li R.H.W., Yeung T.W.Y., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The Endocrine Disruptor Perflurooctane sulfonate (PFOS) modulates Spheroids attachment onto Endometrial cells through Wnt/-catenin inhibition. P2.21. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong. . 2013.


Researcher : Liao S

Project Title:Molecular regulation of meiotic resumption and chromosome segregation in mouse and human oocytes
Investigator(s):Liao S
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Liao S., Cheung K.H., O W.S. and Tang F., Adrenomedullin Increases the Short-Circuit Current in the Mouse Seminal Vesicle: Actions on Chloride Secretion, Biology of Reproduction. 2014.
Liao S., Cheung K.H., Cheung M.P.L., Wong P.F., O W.S. and Tang F., Adrenomedullin increases the short-circuit current in the rat prostate: Receptors, chloride channels, the effects of cAMP and calcium ions and implications on fluid secretion, Andrology. 2014, 2: 474-480.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100: 459-463.e1.


Researcher : Liu S

List of Research Outputs

Chan K.K.L., Leung T.H.Y., Chan D.W., WEI N., Lau T.Y., Liu S., Siu K.Y. and Ngan H.Y.S., Targeting estrogen receptor subtypes (ERalpha and ERbeta) with selective ER modulators in ovarian cancer, Journal of Endocrinology. Great Britain, Bioscientifica Ltd, 2014, 221: 325-336.
LIU X., Siu K.Y., Liu S., Yam J.W.P., Ngan H.Y.S. and Chan D.W., Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer., In: Andrei V. Gudkov and Mikhail V. Blagosklonny, Oncotarget. Impact Journals LLC, 2014, 5: 944–958.


Researcher : Liu VWS

List of Research Outputs

LI C., Liu V.W.S., Chiu P.M., Yao K.M., Ngan H.Y.S. and Chan D.W., Reduced expression of AMPK-beta1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer, In: Christophe Nicot, Molecular Cancer. United Kingdom, BioMed Central, 2014, 13: 49.
Yung M.H., Chan D.W., Liu V.W.S., Yao K.M. and Ngan H.Y.S., Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade, BMC Cancer. 2013, 13: 327.


Researcher : Liu W

Project Title:The Society for Reproduction and Fertility Annual Conference 2013 ; microRNA-34asuppresses embryo implantation through down-regulation of Notch1 in mice
Investigator(s):Liu W
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2013
Completion Date:07/2013


Project Title:Roles of microRNA lethal-7 on blastulation of mice embryos
Investigator(s):Liu W, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2014


List of Research Outputs

CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation , Regional Best Abstract Award (Southeast Asia) - Society for the Study of Reproduction, USA. 2013.
CHEONG W.Y.A., Pang R.T.K., Liu W., KODITHUWAKKU KANKANAMGE S.P.K., Lee C.K.F. and Yeung W.S.B., MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos , Human Reproduction. 2014, 29: 750-762.
CHEONG W.Y.A., Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., Up-regulation of Lin28 and Dicer are required for the activation of mouse blastocysts. , SSR's 46th annual meeting reproductive health: Nano to Global, Montreal, Canada. 2013.
Cheong A.W.Y., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation. , The 46th Annual Meeting of SSR, 22–26 July 2013, Montréal, Québec, Canada.. 2013.


Researcher : Lui MWE

List of Research Outputs

Lui M.W.E., Shek N.W.M., Li R.H.W., Chu S.K.F. and Pun T.C., Management of heterotopic cesarean scar pregnancy by repeated transvaginal ultrasonographic-guided aspiration with successful preservation of normal intrauterine pregnancy and complicated by arteriovenous malformation, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2014, 175: 209-210.
Lui M.W.E., Ngu S.F. and Cheung V.Y.T., Mullerian Cyst of the Uterus Misdiagnosed as Ovarian Cyst on Pelvic Sonography, J Clin Ultrasound. 2013.


Researcher : Luk HMM

List of Research Outputs

Lo I.F.M., Leung K.C., Luk H.M.M., Wong W.L., Tang L.Y.F., Chu Y.W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Chan Y.K. and Chung B.H.Y., Massive parallel sequencing for the genetic diagnosis of rasopathies – a study of 58 Chinese patients in Hong Kong. , Poster presentation in CCMG Annual Meeting, 2013.. 2013.


Researcher : MAK SL

List of Research Outputs

MAK S.L., Chan D.W. and Ngan H.Y.S., The upregulation of miR-141 confers anoikis resistance through targeting KLF12 in ovarian cancer cells, The 18th Research Postgraduate Symposium. LKS Faculty of Medicine, HKU. December 12-13th, 2013. LKS Faculty of Medicine, HKU.


Researcher : Ma WLT

List of Research Outputs

Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.


Researcher : Mok YKS

List of Research Outputs

Mok Y.K.S. and Kan S.Y.A., A community health programme to increase women’s awareness of osteoporosis in Hong Kong. , Poster presentation in IOF Regionals – 4th Asia-Pacific Osteoporosis Meeting, 2013.. 2013.


Researcher : Ng EHY

Project Title:The 17th IFFS World Congress on Fertility and Sterility 1) Measurement of Serum CA-125 Concentrations Does not Improve the Value of Chlamydia Trachomatis Antibody (CAT) in Predicting Tubal Pathology at Laparoscopy 2) A Comparison of the Pain Levels During Egg Collection and Postoperative Side Effects Using Paracervical Block with and without Conscious Sedation
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2001


Project Title:Comparison of the prevalence of polycystic ovary only and polycystic ovary syndrome between two different ethnic populations
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:Role of Sirt1 in generation of mouse induced pluripotent stem cells
Investigator(s):Ng EHY, Lee CKF, Lee CYL, Ng RK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Control of human decidual macrophage differentiation by glycodelin-A
Investigator(s):Ng EHY, Chiu CN, Lee CL, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2012


Project Title:23rd Asian and Oceanic Congress of Obstetrics and Gynaecology; Use of DHEA in Patients with Poor Ovarian Responders
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


Project Title:A randomized controlled trial on the effect of endometrial injury on improving ongoing pregnancy rate in subfertile women undergoing in vitro fertilization treatment
Investigator(s):Ng EHY, Li RHW, Lee CKF, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2014


List of Research Outputs

Cao H., Han M., Ng E.H.Y., Wu X., Flower A., Lewith G. and Liu J.P., Can Chinese herbal medicine improve outcomes of in vitro fertilization? A systematic review and meta-analysis of randomized controlled trials., PLoS One. 2013, 10; 8(12): e81650.
Chai J. and Ng E.H.Y., Evidence-based investigations for subfertility , Journal of Paediatrics, Obstetric & Gynaecology. 2014, 40(3): 125-131.
Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience, Hong Kong Medical Journal. 2014.
Chai J., Lee C.Y., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth rates following in vitro fertilization in women with thyroid autoimmunity and/or subclinical hypothyroidism, ESHRE annual meeting 2013.
Cheung S.Y.C., Chan C.H.Y. and Ng E.H.Y., Stress and anxiety-depression levels following first-trimester miscarriage: a comparison between women who conceived naturally and women who conceived with assisted reproduction, BJOG: An International Journal of Obstetrics & Gynaecology. 2013, 120(9): 1090-1097.
Hu M., Zhang Y., Ma H., Ng E.H.Y. and Wu X., Eastern medicine approaches to male infertility., Seminar In Reproductive Medicine. 2013, 31: 301-310.
Ko K.Y.J., HUANG W., Li R.H.W., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Chiu C.N., Ten best paper award: An in-vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions., Asian and Oceanic Congress of Obstetrics and Gynaecology, 20-23 October 2013, Bangkok, Thailand, . 2013.
Kuang H., Li Y., Wu X., Hou L., Wu T., Liu J. and Ng E.H.Y., Stener-Victorin E, Legro RS, Zhang H (2013) Acupuncture and clomiphene citrate for live birth in polycystic ovary syndrome: study design of a randomized controlled trial. , Evidence-Based Complementary and Alternative Medicine. 2013, 527303.
LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Poster Award (Title of poster presentation: In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model), 13th Congress of the European Society of Contraception and Reproductive Health. 2014.
Lai C.W., Yung S.F. and Ng E.H.Y., Endometrial vascularity is lower in pregnancies with pregnancy-induced hypertension or small-for-gestational age in livebirth after IVF, Ultrasound Obstet Gynecol. 2014.
Lee C.K.F., LIU Y., KODITHUWAKKU KANKANAMGE S.P.K., Ng E.H.Y. and Ho P.C., Ovarian Stimulation modulates human Endometrial Gene expression and Receptivity, The 8th International Huaxia Congress of Endocrinology, 21-22 August 2013, Xi’an, China. (Plenary Lecture CPL-03). 2013.
Lee C.L., Li K., Lam K.W., Ng E.H.Y., Koistinen H., Seppala M., Yeung W.S.B. and Chiu C.N., Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility, Molecular reproduction and development. 2014, 81(6): 482-3.
Lee C.Y.L., PENG Q., CHEN C.H., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 interacts with DNA repair molecules during the initiation phase of reprogramming from mouse fibroblasts to mouse induced pluripotent stem cells, ISSCR 12th Annual Meeting. 2014.
Lee V.C.Y., Li R.H.W., Chai J., Yeung T.W.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles, Fertility and Sterility. 2014, 101: 1288-1293.
Lee V.C.Y., Gao J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta, Hum Reprod. 2013, 28(11): 2912-9.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 205-211.
Li R.H.W., LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model, The 13th European Society of Contraception Congress. 2014.
Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is a better measure of ovarian responsiveness to gonadotrophin stimulation than the number of oocytes during in-vitro fertilization treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 199-203.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is an excellent measure of ovarian responsiveness to gonadotrophin stimulation in in-vitro fertilization, The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology. 2013.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Serum Level of Sex Hormone-Binding Globulin Is a Good Independent Predictor of Metabolic Syndrome in Women with Polycystic Ovary Syndrome, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo. 2014.
Li T.K.T., Li R.H.W., Yeung T.W.Y., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The Endocrine Disruptor Perflurooctane sulfonate (PFOS) modulates Spheroids attachment onto Endometrial cells through Wnt/-catenin inhibition. P2.21. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong. . 2013.
Li Y., Ma H., Zhang Y., Kuang H., Ng E.H.Y., Hou L. and Wu X., Effect of berberine on insulin resistance in women with polycystic ovary syndrome: study protocol for a randomized multicenter controlled trial. , Trials . 2013, 14: 210-226.
Ng E.H.Y., Clinical comparison of gonadotrophin in GnRH antagonist cycles., The Singapore General Hospital Starting Out on Assisted Reproduction (SGH SOAR) organized by Singapore General Hospital, 16-19 September 2013 in Singapore. 2013.
Ng E.H.Y., Controversies in IVF management. , The Singapore General Hospital Starting Out on Assisted Reproduction (SGH SOAR) organized by Singapore General Hospital, 16-19 September, 2013 in Singapore, . 2013.
Ng E.H.Y., Debate: transfer fresh or later. , The 5th Asia Pacific Congress on Building Consensus out of Controversies in Gynecology and Infertility (BCGI-COGI), 21-24 November, 2013, Shanghai, China,. 2013.
Ng E.H.Y., Female reproductive endocrinology., Master Class Reproductive Medicine organized by Obstetrics & Gynaecology Training Centre, Kuala Lumpur Hospital, 20 September, 2013, Kuala Lumpur, Malaysia. 2013.
Ng E.H.Y., IVF: the long and short of it., Master Class Reproductive Medicine organized by Obstetrics & Gynaecology Training Centre, Kuala Lumpur Hospital, 20 September, 2013, Kuala Lumpur, Malaysia,. 2013.
Ng E.H.Y., Luteal phase support: what works and what doesn’t. , The Singapore General Hospital Starting Out on Assisted Reproduction (SGH SOAR) organized by Singapore General Hospital, 16-19 September, 2013 in Singapore, . 2013.
Ng E.H.Y., Proposed trial on the use of traditional Chinese Medicine in IVF methods in clinical trials., Meeting of the project “A national multi-centre randomized controlled trial of acupuncture/clomiphene in polycystic ovary syndrome’ organized by Department of Obstetrics and Gynaecology, Heilongjiang University of Chinese Medicine, 23 August, 2013, Harbin, China, . 2013.
Ng E.H.Y., Proposed trial on the use of traditional Chinese Medicine in IVF methods in clinical trials., The steering committee of the national multi-centre randomized trial of acupuncture/clomiphene in polycystic ovary syndrome organized by Department of Obstetrics and Gynaecology, Heilongjiang University of Chinese Medicine, 14-15 December 2013, Beijing, China . 2013.
Ng E.H.Y., Research ethics in infertility trials. Improving the quality of infertility trials-, The Harbin consensus conference organized by Department of Obstetrics and Gynaecology, Heilongjiang University of Chinese Medicine, 24-26 August 2013, Harbin, China . 2013.
Ng E.H.Y., Ultrasound diagnosis of polycystic ovarian syndrome., Organized by Fertility Society of Australia 2013, September 1-4, 2013, Sydney, Australia . 2013.
Ng E.H.Y., Use of DHEA in poor ovarian responders. , The XXIII Asian & Oceanic Congress of Obstetrics & Gynaecology organized by Asian & Oceanic Federation of Obstetrics & Gynaecology, 20-23 October 2013, Bangkok, Thailand,. 2013.
Ng E.H.Y., Use of acupuncture in mild oligozoospermia., The steering committee of the national multi-centre randomized trial of acupuncture/clomiphene in polycystic ovary syndrome organized by Department of Obstetrics and Gynaecology, Heilongjiang University of Chinese Medicine, 14-15 December, 2013, Beijing, China. 2013.
Ng E.H.Y., Use of atosiban in repeated implantation failure., The 5th International Seminar on repeated IVF-ET failure organized by Southern Medical University, 3-5 August 2013,Guangzhou, China. 2013.
Ng E.H.Y., Uterine contractions and use of oxytocin inhibitors in IVF, Meeting organized by Malaysian Society of ART, 19 September, 2013, Kuala Lumpur, Malaysia, . 2013.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100: 459-463.e1.
Shen W., Zhang Y., Li W., Cong J., Zhou Y., Ng E.H.Y. and Wu X., Effects of tanshinone on hyperandrogenism and the quality of life in women with polycystic ovary syndrome: protocol of a double-blind, placebo-controlled, randomised trial., British Medical Journal. 2013, 3: e003646.
Wang H.Y., Quan S., Zhang R.L., Ye H.Y., Bi Y.L., Jiang Z.M. and Ng E.H.Y., Comparison of serum anti-Mullerian hormone levels following hysterectomy and myomectomy for benign gynaecological conditions., European Journal of Obstetrics and Gynecology and Reproductive Biology. 2013, 171: 368-371.


Researcher : Ng TY

Project Title:A propective randomised controlled trial: prevention of lymphedema by omentoplasty after pelvic lymphadenectomy
Investigator(s):Ng TY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Low Budget High Impact Programme
Start Date:11/2001




Researcher : Ngai CSW

Project Title:Vaginal misoprostol for first trimester termination of pregnancy prior to 9 weeks of gestation
Investigator(s):Ngai CSW, Tang FOS, Chan YM, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:05/1999


Project Title:Cervical assessment in prediction of preterm labour: is three-dimensional ultrasonography a better choice?
Investigator(s):Ngai CSW, Lao TTH, Chen M, Leung KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Multiple pregnancy and gestational diabetes: a physiological response or a pathologic condition?
Investigator(s):Ngai CSW, Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The XIXth Asian and Oceanic Congress of Obstetrics & Gynaecology Should We Screen Sexually Transmitted Diseases for Women Requesting for Termination of Pregnancy?
Investigator(s):Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2005


List of Research Outputs

Shek N.W.M., Ngai C.S.W., Lee C.P., Chan Y.C. and Lao T.T.H., Lifestyle modifications in the development of diabetes mellitus and metabolic syndrome in Chinese women who had gestational diabetes mellitus: a randomized interventional trial, Archives of Gynecology and Obstetrics . 2014, 289: 319-327.


Researcher : Ngan HYS

Project Title:High dose cis-platinum and cyclophosphamide vs taxol in ovarian cancer
Investigator(s):Ngan HYS, Wong RLC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:07/1994


Project Title:Functional characterization and clinical significance of DNp73-C35 in ovarian cancer
Investigator(s):Ngan HYS, Chan KKL, Cheung ANY, Leung THY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2011


Project Title:Characterization of tumor initiating cell population expressing CD55 in cervical cancer.
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012
Completion Date:02/2014


Project Title:Clinical significance and application of HPV-related microRNAs in cervical pre-maglinant lesions and cancer
Investigator(s):Ngan HYS, Liu S, Ng EKO, Cheung ANY, Chan KKL, Kwong A
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013


Project Title:Roles of CD55(+) population and HPV viral proteins on tumor progression in cervical cancer cells
Investigator(s):Ngan HYS, Leung THY, Cheung ANY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013
Completion Date:08/2014


Project Title:Roles of HPV-E6 protein and CD55(+) population in regulating radio-resistance in cervical cancer cells
Investigator(s):Ngan HYS, Chan KKL, Leung THY, Cheung ANY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


Project Title:Functional characterization of subpopulation cells expressing transferrin receptor (CD71) and the roles of HPV viral protein in cervical cancer
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Chan D.W., YUNG M.H. and Ngan H.Y.S., MAP30 protein of Momordica charantia functions as a natural AMPK activator in combating tumorigenic and chemoresistant capacities of ovarian cancer, Croucher Advanced Study Institute (ASI): Tumour Microenvironment – Cancer Cell Metabolism. LKS Faculty of Medicine, HKU. 13 November, 2013.. Croucher Advanced Study Institute (ASI), 2013.
Chan D.W. and Ngan H.Y.S., Targeting AMPK as a valid therapeutic intervention in ovarian cancer, International Workshop on Women's Reproductive Health Research. 2014.
Chan D.W., CAI C. and Ngan H.Y.S., Targeting TAK1/NF-κB signalling axis abrogates omental metastasis of ovarian cancer, COLD SPRING HARBOR ASIA CONFERENCES: Cell Signaling in Metabolism, Inflammation and Cancer. Suzhou Dushu Lake Conference Center September 2-26, 2013. Suzhou, Jiangsu Province, China. . Suzhou, Jiangsu Province, China., 2013.
Chan K.K.L., Leung T.H.Y., Chan D.W., WEI N., Lau T.Y., Liu S., Siu K.Y. and Ngan H.Y.S., Targeting estrogen receptor subtypes (ERalpha and ERbeta) with selective ER modulators in ovarian cancer, Journal of Endocrinology. Great Britain, Bioscientifica Ltd, 2014, 221: 325-336.
Chan R.W.S., Mak A.S., Yeung W.S.B., Lee C.K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S., Human female reproductive tract epithelial cell culture., Methods Mol Biol.. 2013, 945: 347-363.
Kwan T.T.C., Chan K.K.L., Chu M.Y.M., Ho R.T.H., Chan C.L.W. and Ngan H.Y.S., Post-hysterectomy fatigue in women with malignant or benign gynaecologic diseases, The 20th Hong Kong International Cancer Congress (14-15 Nov, 2013). 2013.
Kwan T.T.C., Chan K.K.L., Chu M.Y.M., Ho R.T.H., Chan C.L.W. and Ngan H.Y.S., Post-hysterectomy fatigue in women with malignant or benign gynaecologic diseases, The 20th Hong Kong International Cancer Congress (14-15, November, 2013) Hong Kong. 2013.
LEUNG O.N., Deng W., Ye T., Ngan H.Y.S., Tsao G.S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
LI C., Liu V.W.S., Chiu P.M., Yao K.M., Ngan H.Y.S. and Chan D.W., Reduced expression of AMPK-beta1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer, In: Christophe Nicot, Molecular Cancer. United Kingdom, BioMed Central, 2014, 13: 49.
LIU X., Siu K.Y., Liu S., Yam J.W.P., Ngan H.Y.S. and Chan D.W., Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer., In: Andrei V. Gudkov and Mikhail V. Blagosklonny, Oncotarget. Impact Journals LLC, 2014, 5: 944–958.
Lam S.N., Mak A.S.C., Yam J.W.P., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S.T., Targeting estrogen-related receptor alpha inhibits epithelial-to-mesenchymal transition and stem cell properties of ovarian cancer cells, In: Lam SS, Mak AS, Yam JW, Cheung AN, Ngan HY, Wong AS, Mol Ther. 2014.
Lee E.Y.P., Khong P.L., Tse K.Y., Chan K.K.L., Chu M.M.Y. and Ngan H.Y.S., Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value. , Nuclear Medicine Communications. 2013, 34: 1185-1189.
Lee E.Y.P., Khong P.L., Tse K.Y., Chan K.K.L., Chu M.Y.M. and Ngan H.Y.S., Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value, Nucl Med Commun. 2013, 34(12 ): 1185-1189.
Lee E.Y.P., Khong P.L., Tse K.Y., Chu M.Y., Chan K.K.L. and Ngan H.Y.S., SUVmax distinguishes the aggressive from the indolent subtypes of uterine sarcoma, International Cancer Imaging Society and 13th Annual Teaching Course. 2013.
Leung C.O., Deng W., Ye T.M., Ngan H.Y.S., Tsao S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
Leung T.H.Y., Chan K.K.L. and Ngan H.Y.S., Human papilloma virus E6 protein enhances CD55 expression on cervical cancer cell surface which promotes radio-resistance and cancer aggressiveness, The 2014 Controlling Cancer Summit, London, UK. 2014.
Leung T.H.Y., WONG C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cells, British Journal of Cancer. 2013, 109: 965-975.
MAK S.L., Chan D.W. and Ngan H.Y.S., The upregulation of miR-141 confers anoikis resistance through targeting KLF12 in ovarian cancer cells, The 18th Research Postgraduate Symposium. LKS Faculty of Medicine, HKU. December 12-13th, 2013. LKS Faculty of Medicine, HKU.
Ngan H.Y.S., How imaging help a gynaecological oncologist, 5th Joint Scientific Meeting of The Royal College of Radiologists & Hong Kong College of Radiologists and 21st Annual Scientific Meeting of Hong Kong College of Radiologists, Hong Kong, November 3. 2013.
Ngan H.Y.S., Chien Tien Hsu Memorial Lecture: “From bench to bedside”, Bangkok, Thailand, XXIII Asia Oceanic of Obstetrics & Gynecology Congress (AOCOG), October 20-23. 2013.
Ngan H.Y.S., Differential roles of estrogen receptor subtypes and variants in ovarian cancer: implications for personalized hormonal treatment , International Workshop on Women’s Reproductive Health Research, Ottawa, Canada, April 11-13. 2014.
Ngan H.Y.S., Editorial Board Member - Journal of Clinical Oncology (Chinese Edition) since 2000. 2014.
Ngan H.Y.S., Editorial Board Member - Journal of Medical Association of Thailand. 2014.
Ngan H.Y.S., Editorial Board Member - Journal of Obstetrics and Gynaecology Research since 1997. 2014.
Ngan H.Y.S., Editorial Board Member - Journal of Paediatrics, Gynaecology and Obstetrics since 1997. 2014.
Ngan H.Y.S., Editorial Board Member - The Hong Kong Medical Journal. 2014.
Ngan H.Y.S., Editorial Board Member of 实用婦產科雜誌(編 委). 2014.
Ngan H.Y.S., Editorial Member - 中華婦產科雜誌. 2014.
Ngan H.Y.S., Editorial Member - 國際婦產科學雜誌第七屆編輯委員會. 2014.
Ngan H.Y.S., Endometrial Cancer – standard of care, 23rd Malaysian Congress of O&G, Selangor, Malaysia, June 6-8. 2014.
Ngan H.Y.S., FIGO guidelines and new staging in ovarian cancer, 第四屆華南卵巢癌高峰論壇, Guangzhou, December 7. 2013.
Ngan H.Y.S., Gold Medal in recognition of the significant contribution to our knowledge of trophoblastic disease at the conference, International Society for the Study of Trophoblastic Diseases (ISSTD), VII World Congress on Gestational Trophoblasic Diseases, September 19-23. 2013.
Ngan H.Y.S. and Chan K.K.L., Gynaecological oncology, In: Ian Symonds, Sir Sabaratnam Arulkumaran, E Malcolm Symonds (Emeritus Editor), Essential Obstetrics Gynaecology, Churchill Livingstone 2013, Chapter 20, Fifth Edition. 2013, 317-339.
Ngan H.Y.S., HPV Symposium: “HPV infection: cervical cancer burden and prevention strategies”, Bangkok, Thailand, XXIII Asia Oceanic of Obstetrics & Gynecology Congress (AOCOG), October 20-23. 2013.
Ngan H.Y.S., Minimally Invasive Radical Hysterectomy in Hong Kong, International Symposium on Radical Hysterectomy, Seoul, Korea, August 2-4. 2013.
Ngan H.Y.S., New advances in surgical treatment of gynaecological , cancersSymposium on Evidence-Based Practice in Obstetrics & Gynaecology, HKU-Shenzhen Hospital, November 30. 2013.
Ngan H.Y.S., Overview on Cervical Cancer Control and Prevention in Hong Kong, HKCOG Postgraduate Seminar, March 9, 2014. 2014.
Ngan H.Y.S., Overview on cervical cancer and prevention in Asian Countries, The 3rd Biennial Meeting of the Asian Society of Gynecology Oncology and the 55th Meeting of Japan Society of Gynecologic Oncology, Kyoto, Japan, December 13-15. 2013.
Ngan H.Y.S., Placental site trophoblastic tumour and epitheloid trophoblastic tumour, XVII World Congress on Gestational Trophoblastic Diseases, Chicago, USA, September 19-23. 2013.
Ngan H.Y.S., Plenary Speaker of "Significance of p73 in the sensitivity of cancer treatment in gynaecological cancers" and Modulator of Gynecologic Cancer session, International Workshop on Women’s Reproductive Health Research, Ottawa, Canada, 12 April. 2014.
Ngan H.Y.S., Recent update on Cervical Intra-epithelial Neoplasia & Cancer , Symposium of Update on Cervical Intra-epithelial Neoplasia and Cancer, Hong Kong, June 22. 2014.
Ngan H.Y.S., Robotic Gyn Oncology Adoption in Hong Kong, speak for Asia distrubutors and Intuitive Surgical management team, Hong Kong, December 5. 2013.
Ngan H.Y.S., Robotic assisted laparoscopic surgery in gynaecological cancer , 5th Beijing/Hong Kong Medical Exchange Conference, Changsha, PRC, October 12-13. 2013.
Ngan H.Y.S., Surgical Management of Abnormalities in Cervical Neoplasia, Asia Oceania Research Organization on Genital Infections and Neoplasia (AOGIN) Biennial Conference, Beijing, April 25-27. 2014.
Ngan H.Y.S., World trends of gynecologic malignancies in young women, AGOG-AOFOG Oncology Committee Joint Symposium, Tokyo, Japan, July 19. 2013.
Pang R.T.K., LEUNG O.N., YE T., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., CERVICAL CANCER CD133 POSITIVE CELLS POSSESS TUMOR INITIATING CELLS PROPERTIES, 18th International Meeting of the European Society of Gynaecological Oncology (ESGO). International Journal of Gynecological Cancer, 2013.
Siu K.Y., Wong E.S.Y., Kong S.H., Chan H.Y., JIANG L., Wong G.W., Chan K.K.L., Ngan H.Y.S., Le X.F. and Cheung A.N.Y., Stem Cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-Cadherin and Fox JI and contributes to adverse clinical outcome in ovarian cancers. 2013, 32(30): 3500-9.
Tang K.S., Kwong A., Tam K.F., Cheung A.N.Y., Ngan H.Y.S., Xia W. and Wong A.S.T., BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis, In: Tang MK, Kwong A, Tam KF, Cheung AN, Ngan HY, Xia W, Wong AS, Cancer Lett. 2014.
Yung M.H., Chan D.W., Liu V.W.S., Yao K.M. and Ngan H.Y.S., Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade, BMC Cancer. 2013, 13: 327.
Zhao F., Siu K.Y., Wong G.W., Wong E.S.Y., Jiang L.L., Tam K.F., Ngan H.Y.S., Le X.F., Lam E.W.F. and Cheung A.N.Y., Role of FOXM1 in ovarian carcinogenesis, In: Zhao F, Siu MK, Wong OG, Wong ES, Jiang LL, Tam KF, Ngan HY, Le XF, Lam EWF, Cheung AN, AACR conference Advances in Ovarian Cancer Research: From Concept to Clinic. September 18-21, 2013. Miami, USA. Proceedings of the American Association for Cancer Research. 2013.


Researcher : Ngu SF

Project Title:Vaginal microflora in women who use ring pessary for pelvic organ prolapse
Investigator(s):Ngu SF, Seneviratne CJ, Ma WSP, Cheung VYT, Pun TC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:06/2014


Project Title:Clinical significance of JAG1/NOTCH1 signaling in cisplatin-resistance of ovarian clear cell carcinoma
Investigator(s):Ngu SF, Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Cheung V.Y.T. and Ngu S.F., Diagnosis and Follow Up of Cesarean Scar Ectopic Pregnancies by Sonography, The 23rd Asian & Oceanic Congress of Obstetrics & Gynaecology, Bangkok, Thailand. 2013.
Ko K.Y.J., Seto T.Y.M., Ngu S.F. and Cheung V.Y.T., Urethral Prolapse in a postmenopausal woman, J Obstet Gynaecol Canada. 2014, 36(2): 105.
Lui M.W.E., Ngu S.F. and Cheung V.Y.T., Mullerian Cyst of the Uterus Misdiagnosed as Ovarian Cyst on Pelvic Sonography, J Clin Ultrasound. 2013.
Ngai F.W. and Ngu S.F., Family Sense Of Coherence And Family Adaptation Among Childbearing Couples, Journal of Nursing Scholarship. 2014, 46: 82-90.
Ngai F.W. and Ngu S.F., Family sense of coherence and quality of life during the transition to parenthood, 21st IUHPE World Conference on Health Promotion. 2013.
Ngai F.W. and Ngu S.F., Quality of life during the transition to parenthood in Hong Kong: a longitudinal study, Journal of Psychosomatic Obstetrics and Gynecology. 2013, 34: 157-162.
Ngu S.F. and Chan K.K.L., Management of Chemoresistant and Quiescent Gestational Trophoblastic Disease, Current Obstetrics and Gynecology Reports. 2014.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Surgical Management of Adnexal Masses in Pregnancy, JSLS. 2014, 18(1): 71-75.
Ngu S.F., Ko K.Y.J. and Cheung V.Y.T., Value of human chorionic gonadotropin levels in diagnosing cervical ectopic pregnancy. , Acta Obstetricia et Gynecologica Scandinavica. 2013, 92(5): 608-609.
Seto T.Y.M., Ip P.P.C., Ngu S.F., Cheung A.N.Y. and Pun T.C., Diagnostic Accuracy of Endometrial Polyps in Pipelle Endometrial Samples: A Clinicopathologic Study of 195 Cases, United States & Canadian Academy of Pathology’s 103rd Annual Meeting. 2014.


Researcher : Ong CYT

Project Title:To determine the correlation of changes in maternal levels of pregnancy-associated plasma protein A (PAPP-A) and free [beta] human chorionic gonadotrophin (F[beta]-hCG) with placental development and fetal outcomes
Investigator(s):Ong CYT, Lao TTH, Leung WC, Leung KY, Lam HSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:First trimester prediction of fetal α-thalassaemia-1 with maternal serum markers, nuchal translucency measurement and three dimentional ultrasound measurement of placental volume
Investigator(s):Ong CYT, Chen M, Leung KY, Tang MHY, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Maternal serum level of ADAM 12 as an early marker of trisomy 21, trisomy 13 and trisomy 18
Investigator(s):Ong CYT, Lee CP, Lau ETK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2007




Researcher : PENG Q

List of Research Outputs

Lee C.Y.L., PENG Q., CHEN C.H., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 interacts with DNA repair molecules during the initiation phase of reprogramming from mouse fibroblasts to mouse induced pluripotent stem cells, ISSCR 12th Annual Meeting. 2014.


Researcher : Pang RTK

Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang RTK, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007


Project Title:The 18th ESGO International Meeting; CERVICAL CANCER CD133 POSITIVE CELLS POSSESS TUMOR INITIATING CELLS PROPERTIES
Investigator(s):Pang RTK
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


List of Research Outputs

CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation , Regional Best Abstract Award (Southeast Asia) - Society for the Study of Reproduction, USA. 2013.
CHEONG W.Y.A., Pang R.T.K., Liu W., KODITHUWAKKU KANKANAMGE S.P.K., Lee C.K.F. and Yeung W.S.B., MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos , Human Reproduction. 2014, 29: 750-762.
CHEONG W.Y.A., Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., Up-regulation of Lin28 and Dicer are required for the activation of mouse blastocysts. , SSR's 46th annual meeting reproductive health: Nano to Global, Montreal, Canada. 2013.
Cheong A.W.Y., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation. , The 46th Annual Meeting of SSR, 22–26 July 2013, Montréal, Québec, Canada.. 2013.
KWAN C.K., Pang R.T.K., LEUNG O.N., YE T., Yeung W.S.B. and Ho P.C., Effects of In-Vitro Culture And Bisphenol A Exposure On DNA Methylation Of Imprinted Genes May Be Obtainable In High Resolution From A Single Mouse Embryo, Society for the Study of Reproduction 2013: 46th General Meeting Reproductive Health: Nano to Global. 2013.
LEUNG O.N., Deng W., Ye T., Ngan H.Y.S., Tsao G.S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.
Leung C.O., Deng W., Ye T.M., Ngan H.Y.S., Tsao S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
Pang R.T.K., LEUNG O.N., YE T., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., CERVICAL CANCER CD133 POSITIVE CELLS POSSESS TUMOR INITIATING CELLS PROPERTIES, 18th International Meeting of the European Society of Gynaecological Oncology (ESGO). International Journal of Gynecological Cancer, 2013.
Yeung W.S.B., Lee C.K.F., Chiu C.N., Lee C.Y.L. and Pang R.T.K., Interactions between gametes/preimplantation embryos with the female reproductive tract, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014. 2014.


Researcher : Pun TC

List of Research Outputs

Lui M.W.E., Shek N.W.M., Li R.H.W., Chu S.K.F. and Pun T.C., Management of heterotopic cesarean scar pregnancy by repeated transvaginal ultrasonographic-guided aspiration with successful preservation of normal intrauterine pregnancy and complicated by arteriovenous malformation, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2014, 175: 209-210.
Ngu S.F., Cheung V.Y.T. and Pun T.C., Surgical Management of Adnexal Masses in Pregnancy, JSLS. 2014, 18(1): 71-75.
Seto T.Y.M., Ip P.P.C., Ngu S.F., Cheung A.N.Y. and Pun T.C., Diagnostic Accuracy of Endometrial Polyps in Pipelle Endometrial Samples: A Clinicopathologic Study of 195 Cases, United States & Canadian Academy of Pathology’s 103rd Annual Meeting. 2014.


Researcher : SO KH

List of Research Outputs

Guo Y., Lee C.L., SO K.H., Gao J., Yeung W.S.B., Yao Y.Q. and Lee C.K.F., Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast invasion, PLoS One. 2013, 8: e76023.
KOTTAWATTA K.S.A., SO K.H., Yeung W.S.B. and Lee C.K.F., Modulation of OLFM1 and CTBP1 Expression via miR-132/-212 in Human Endometrial Epithelial Cells. P2.16. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong.. 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Human chorionic gonadotropin enhances receptivity of Fallopian tube through down-regulation of Olfactomedin-1., The 46th Annual Meeting of SSR, 22–26 July, 2013, Montréal, Québec, Canada.. 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast onto endometrial epithelial cells through activation of ERK and Wnt/beta-catenin signaling pathway. , The 8th International Huaxia Congress of Endocrinology, 21-22 August, 2013, Xi’an, China.. 2013.
So K.H., Lee C.Y.L., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast surrogate onto endometrial/Oviductal epithelial cell monolayer through activation of ERK and Wnt/beta-catenin signaling pathway. OP3., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 24 November, 2013, Hong Kong.. 2013.
YEUNG A.S.-.Y., So K.H., Yeung W.S.B. and Lee C.K.F., Generation of Trs4 knockout mice for spermatogenesis studies. P1.29., The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 December, 2013, Hong Kong.. 2013.


Researcher : Seto TYM

List of Research Outputs

Ko K.Y.J., Seto T.Y.M., Ngu S.F. and Cheung V.Y.T., Urethral Prolapse in a postmenopausal woman, J Obstet Gynaecol Canada. 2014, 36(2): 105.
Seto T.Y.M., Ip P.P.C., Ngu S.F., Cheung A.N.Y. and Pun T.C., Diagnostic Accuracy of Endometrial Polyps in Pipelle Endometrial Samples: A Clinicopathologic Study of 195 Cases, United States & Canadian Academy of Pathology’s 103rd Annual Meeting. 2014.


Researcher : Shek NWM

List of Research Outputs

Cheung K.W., Shek N.W.M. and Chan K.H., An unusual cause of postpartum collapse:undiagnosed myasthenia gravis, Journal of Obstetrics and Gynecology . 2013, 33(5): 528.
Lui M.W.E., Shek N.W.M., Li R.H.W., Chu S.K.F. and Pun T.C., Management of heterotopic cesarean scar pregnancy by repeated transvaginal ultrasonographic-guided aspiration with successful preservation of normal intrauterine pregnancy and complicated by arteriovenous malformation, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2014, 175: 209-210.
Shek N.W.M., Ngai C.S.W., Lee C.P., Chan Y.C. and Lao T.T.H., Lifestyle modifications in the development of diabetes mellitus and metabolic syndrome in Chinese women who had gestational diabetes mellitus: a randomized interventional trial, Archives of Gynecology and Obstetrics . 2014, 289: 319-327.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 36.


Researcher : Siu KY

Project Title:Effects of folate and folate receptor on ovarian and endometrial cancer: an in vitro study
Investigator(s):Siu KY, Cheung ANY
Department:Pathology
Source(s) of Funding:American Institute for Cancer Research (AICR) - General Award
Start Date:07/2006


Project Title:p21-activated kinase 4: a prognostic and therapeutic target for ovarian carcinoma?
Investigator(s):Siu KY, Cheung ANY, Ngan HYS
Department:Pathology
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:10/2007


List of Research Outputs

Chan K.K.L., Leung T.H.Y., Chan D.W., WEI N., Lau T.Y., Liu S., Siu K.Y. and Ngan H.Y.S., Targeting estrogen receptor subtypes (ERalpha and ERbeta) with selective ER modulators in ovarian cancer, Journal of Endocrinology. Great Britain, Bioscientifica Ltd, 2014, 221: 325-336.
LIU X., Siu K.Y., Liu S., Yam J.W.P., Ngan H.Y.S. and Chan D.W., Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer., In: Andrei V. Gudkov and Mikhail V. Blagosklonny, Oncotarget. Impact Journals LLC, 2014, 5: 944–958.
Siu K.Y., Wong E.S.Y., Kong S.H., Chan H.Y., JIANG L., Wong G.W., Chan K.K.L., Ngan H.Y.S., Le X.F. and Cheung A.N.Y., Stem Cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-Cadherin and Fox JI and contributes to adverse clinical outcome in ovarian cancers. 2013, 32(30): 3500-9.


Researcher : So KH

List of Research Outputs

Guo Y., Lee C.L., SO K.H., Gao J., Yeung W.S.B., Yao Y.Q. and Lee C.K.F., Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast invasion, PLoS One. 2013, 8: e76023.
KOTTAWATTA K.S.A., SO K.H., Yeung W.S.B. and Lee C.K.F., Modulation of OLFM1 and CTBP1 Expression via miR-132/-212 in Human Endometrial Epithelial Cells. P2.16. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong.. 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Human chorionic gonadotropin enhances receptivity of Fallopian tube through down-regulation of Olfactomedin-1., The 46th Annual Meeting of SSR, 22–26 July, 2013, Montréal, Québec, Canada.. 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast onto endometrial epithelial cells through activation of ERK and Wnt/beta-catenin signaling pathway. , The 8th International Huaxia Congress of Endocrinology, 21-22 August, 2013, Xi’an, China.. 2013.
So K.H., Lee C.Y.L., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast surrogate onto endometrial/Oviductal epithelial cell monolayer through activation of ERK and Wnt/beta-catenin signaling pathway. OP3., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 24 November, 2013, Hong Kong.. 2013.
YEUNG A.S.-.Y., So K.H., Yeung W.S.B. and Lee C.K.F., Generation of Trs4 knockout mice for spermatogenesis studies. P1.29., The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 December, 2013, Hong Kong.. 2013.


Researcher : TSANG H

List of Research Outputs

TSANG H., CHEUNG T.Y., KODITHUWAKKU KANKANAMGE S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling, Reprod Toxicol. 2013, 42: 164-71.


Researcher : Tam KF

List of Research Outputs

Tang K.S., Kwong A., Tam K.F., Cheung A.N.Y., Ngan H.Y.S., Xia W. and Wong A.S.T., BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis, In: Tang MK, Kwong A, Tam KF, Cheung AN, Ngan HY, Xia W, Wong AS, Cancer Lett. 2014.
Zhao F., Siu K.Y., Wong G.W., Wong E.S.Y., Jiang L.L., Tam K.F., Ngan H.Y.S., Le X.F., Lam E.W.F. and Cheung A.N.Y., Role of FOXM1 in ovarian carcinogenesis, In: Zhao F, Siu MK, Wong OG, Wong ES, Jiang LL, Tam KF, Ngan HY, Le XF, Lam EWF, Cheung AN, AACR conference Advances in Ovarian Cancer Research: From Concept to Clinic. September 18-21, 2013. Miami, USA. Proceedings of the American Association for Cancer Research. 2013.


Researcher : Tang FOS

Project Title:A prospective randomized comparison of sublingual and vaginal misoprostol in termination of pregnancy in the second trimester
Investigator(s):Tang FOS, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:10/2000




Researcher : Tang GWK

Project Title:A cross sectional health care study of Chinese perimenopausal women in Hong Kong
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:01/1993


List of Research Outputs

Tang G.W.K., Adviser of Editor Board, The Hong Kong Practitioner, 2014.
Tang G.W.K., Getting through complaints with difficult patients in challenging situations, "Doctor, I will sue you!" Coping with adverse events, complaints or litigations in Obstetrics & Gynaecology. Postgraduate Study Day,Dept. of O&G, QMH, 2014.
Tang G.W.K., Reviewer for ISRN Obstetrics and Gynecology, 2014.
Tang G.W.K., The New Reality in Medicine-Caring for Patients with Multiple Co-Morbidities, 2nd AMM-AMS-HKAM Tripartite Congress & 46th Singapore-Malaysia Congress of Medicine, 23-24/8/2013 Grand Copthorne Waterfront Hotel. Singapore, 2013.
Tang G.W.K., 深港合作與思路創新 "香港大學深圳醫院運作 - 更廣泛的醫療合作", 第七屆"深港合作論壇" 15/11/2013 . 深圳馬哥孛羅好日子酒店 深圳福田中心區福華一路28號, 2013.
Tang G.W.K., 開放與合作: 創新醫改體制 "香港大學深圳醫院經驗分享", 第七屆中國醫院院長年會, 16/11/2013. 深圳, 邁瑞公司 深圳市南區新技術產業園區科技南12號, 2013.
Zhong L., Tong Y., Tang G.W.K., Zhang Z., Choi W.K., Cheng K., Sze C.W., Wai K., Liu Q. and Yu X., A randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong perimenopausal women, Menopause . 2013, 20: 767-776.


Researcher : Tang MHY

List of Research Outputs

Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.
Ko K.O., Lee H.H., Lau B., Wong W.S., Kan S.Y.A., Tang M.H.Y., Poon C.F. and Leung K.Y., Two unusual cases of haemoglobin Bart’s hydrops fetalis screened negative on universal prenatal screening for thalassaemia. , Poster presentation in ISUOG World Congress, 2013.. 2013.
Kou K.O.T., Lee H., Lau B., Wong W.S., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Poon C.F. and Leung K.Y., Two unusual cases of haemoglobin Bart’s hydrops fetalis due to uniparental disomy or non-paternity., Fetal Diagnosis and Therapy. 2013, 14: 14.
Lo I.F.M., Leung K.C., Luk H.M., Tang V.H.M., Gao W., Wong W.L., Tang L.Y.F., Chu W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Ma C.H., Jin D., Chan Y.K. and Chung B.H.Y., Identifying genetic mutations in patients with RASopathies using a new generation sequencing diagnostic pipeline in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 19.
Lo I.F.M., Leung K.C., Luk H.M.M., Wong W.L., Tang L.Y.F., Chu Y.W.Y., Kan S.Y.A., Tang M.H.Y., Lam S.T.S., Yang W., Chan Y.K. and Chung B.H.Y., Massive parallel sequencing for the genetic diagnosis of rasopathies – a study of 58 Chinese patients in Hong Kong. , Poster presentation in CCMG Annual Meeting, 2013.. 2013.
Luk H.M., Wong V.C.H., Lo I.F.M., Chan Y.K., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Tang W.F., She W.M.K., Chu W.Y., Sin W.K. and Chung B.H.Y., A prenatal case of split-hand malformation associated with 17p13.3 triplication – A dilemma in genetic counseling, European Journal of Medical Genetics. Elsevier, 2014, 57: 81-84.
Tao Q.V., Chu W.Y., Chan Y.K., Lau E.T.K., Mok T.K.G., Tso W.Y.W., Liu A.P.Y., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Annual Scientific Meeting, Hong Kong College of Paediatricians, HK, 7 December 2013. 37.
Tao Q.V., She W., Chu W.Y., Tso W.Y.W., Chan K.Y., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., Integration of chromosomal microarray into paediatric clinical care in Hong Kong, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 23.
YEUNG K.S., Chee W.Y.Y., Luk H.M., Tang M.H.Y., Lau E.T.K., Shuen Y.A., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Evidence of spread of X chromosome inactivation on chromosome 15 in a girl with an unbalanced t(X;15) transolcation, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 64.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, Joint Annual Scientific Meeting, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd, , 15 June 2014. 36.


Researcher : Tang WF

List of Research Outputs

Kan S.Y.A., Lau E.T.K., Tang W.F., Chan S.S.Y., Ding S.C.K., Chan Y.K., Lee C.P., Hui P.W., Chung B.H.Y., Leung K.Y., Ma W.L.T., Leung W.C. and Tang M.H.Y., Whole-genome Array CGH Evaluation for Replacing Prenatal Karyotyping in Hong Kong [in-press], PLOS One. 2014, 9(2): e87988.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan K.Y., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patient with conotruncal anomalies: Dysmorphisms, clinical features and under-diagnosis, Joint Annual Scientific Meeting 2013, The HK Paediatric Society and HK Paediatrics Nurses Association Ltd., QEH, 8 September 2013. 52.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., 22q11.2 deletion syndrome in adult Chinese patients with conotruncal anomalies: dysmorphisms, clinical features and under-diagnosis, Hong Kong Paediatric Society Annual Scientific Meeting. 2013.
Liu A.P.Y., Chow P.C., Lee P.P.W., Mok T.K.G., Tang W.F., Lau E.T.K., Lam S.T.S., Chan Y.K., Kan S.Y.A., Chau A.K.T., Cheung Y.F., Lau Y.L. and Chung B.H.Y., Under-recognition of 22q11.2 deletion in adult Chinese patients with conotruncal anomalies: Implications in transitional care, European Journal of Medical Genetics. Elsevier, 2014, 57: 306-311.
Luk H.M., Wong V.C.H., Lo I.F.M., Chan Y.K., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Tang W.F., She W.M.K., Chu W.Y., Sin W.K. and Chung B.H.Y., A prenatal case of split-hand malformation associated with 17p13.3 triplication – A dilemma in genetic counseling, European Journal of Medical Genetics. Elsevier, 2014, 57: 81-84.


Researcher : Tse KY

List of Research Outputs

Lee E.Y.P., Khong P.L., Tse K.Y., Chan K.K.L., Chu M.M.Y. and Ngan H.Y.S., Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value. , Nuclear Medicine Communications. 2013, 34: 1185-1189.
Lee E.Y.P., Khong P.L., Tse K.Y., Chan K.K.L., Chu M.Y.M. and Ngan H.Y.S., Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value, Nucl Med Commun. 2013, 34(12 ): 1185-1189.
Lee E.Y.P., Khong P.L., Tse K.Y., Chu M.Y., Chan K.K.L. and Ngan H.Y.S., SUVmax distinguishes the aggressive from the indolent subtypes of uterine sarcoma, International Cancer Imaging Society and 13th Annual Teaching Course. 2013.


Researcher : WANG Y

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.


Researcher : WEI N

List of Research Outputs

Chan K.K.L., Leung T.H.Y., Chan D.W., WEI N., Lau T.Y., Liu S., Siu K.Y. and Ngan H.Y.S., Targeting estrogen receptor subtypes (ERalpha and ERbeta) with selective ER modulators in ovarian cancer, Journal of Endocrinology. Great Britain, Bioscientifica Ltd, 2014, 221: 325-336.


Researcher : WONG CS

List of Research Outputs

Leung T.H.Y., WONG C.S., Chan K.K.L., Chan D.W., Cheung A.N.Y. and Ngan H.Y.S., The interaction between C35 and ΔNp73 promotes chemo-resistance in ovarian cancer cells, British Journal of Cancer. 2013, 109: 965-975.


Researcher : WONG HHV

List of Research Outputs

Chiu C.N., WONG S.T., Lee C.L., Lam K.W., WONG H.H.V. and Yeung W.S.B., Control of human trophoblast functions by adrenomedullin, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
WONG H.H.V., WAN H.L., CHAN Y.L. and Chiu C.N., Best Oral Presentation Award: Isolation of HLAG+CK7+ Trophoblastic Cells from Endocervix for Potential Use in Prenatal Genetic., The Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction, 24 November 2013, Hong Kong. . 2013.
WONG H.H.V., WAN H.L., CHAN Y.L. and Chiu C.N., Best Poster Presentation Award: Noninvasive Recovery of Endocervical Trophoblasts for Potential Use in Prenatal Genetic Diagnosis., The 18th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 11-12 December 2013, Hong Kong.. 2013.
Wong B.S., Lam K.K., Lee C.L., WONG H.H.V., Lam M.P., Chu I.K., Yeung W.S.B. and Chiu C.N., Adrenomedullin enhances invasion of human extravillous cytotrophoblast-derived cell lines by regulation of urokinase plasminogen activator expression and s-nitrosylation. (Feb 2013), Biology of Reproduction. 2013, 88(2): 34.


Researcher : WONG ST

List of Research Outputs

Chiu C.N., WONG S.T., Lee C.L., Lam K.W., WONG H.H.V. and Yeung W.S.B., Control of human trophoblast functions by adrenomedullin, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.


Researcher : Wan HLT

List of Research Outputs

Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.


Researcher : Wong CK

List of Research Outputs

Li T.K.T., Li R.H.W., Yeung T.W.Y., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The Endocrine Disruptor Perflurooctane sulfonate (PFOS) modulates Spheroids attachment onto Endometrial cells through Wnt/-catenin inhibition. P2.21. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong. . 2013.


Researcher : YE T

List of Research Outputs

KWAN C.K., Pang R.T.K., LEUNG O.N., YE T., Yeung W.S.B. and Ho P.C., Effects of In-Vitro Culture And Bisphenol A Exposure On DNA Methylation Of Imprinted Genes May Be Obtainable In High Resolution From A Single Mouse Embryo, Society for the Study of Reproduction 2013: 46th General Meeting Reproductive Health: Nano to Global. 2013.
LEUNG O.N., Deng W., Ye T., Ngan H.Y.S., Tsao G.S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
Pang R.T.K., LEUNG O.N., YE T., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., CERVICAL CANCER CD133 POSITIVE CELLS POSSESS TUMOR INITIATING CELLS PROPERTIES, 18th International Meeting of the European Society of Gynaecological Oncology (ESGO). International Journal of Gynecological Cancer, 2013.


Researcher : YEUNG AS-Y

List of Research Outputs

YEUNG A.S.-.Y., So K.H., Yeung W.S.B. and Lee C.K.F., Generation of Trs4 knockout mice for spermatogenesis studies. P1.29., The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 December, 2013, Hong Kong.. 2013.


Researcher : YUNG MH

List of Research Outputs

Chan D.W., YUNG M.H. and Ngan H.Y.S., MAP30 protein of Momordica charantia functions as a natural AMPK activator in combating tumorigenic and chemoresistant capacities of ovarian cancer, Croucher Advanced Study Institute (ASI): Tumour Microenvironment – Cancer Cell Metabolism. LKS Faculty of Medicine, HKU. 13 November, 2013.. Croucher Advanced Study Institute (ASI), 2013.
Yung M.H., Chan D.W., Liu V.W.S., Yao K.M. and Ngan H.Y.S., Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade, BMC Cancer. 2013, 13: 327.


Researcher : Ye T

List of Research Outputs

KWAN C.K., Pang R.T.K., LEUNG O.N., YE T., Yeung W.S.B. and Ho P.C., Effects of In-Vitro Culture And Bisphenol A Exposure On DNA Methylation Of Imprinted Genes May Be Obtainable In High Resolution From A Single Mouse Embryo, Society for the Study of Reproduction 2013: 46th General Meeting Reproductive Health: Nano to Global. 2013.
LEUNG O.N., Deng W., Ye T., Ngan H.Y.S., Tsao G.S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
Pang R.T.K., LEUNG O.N., YE T., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., CERVICAL CANCER CD133 POSITIVE CELLS POSSESS TUMOR INITIATING CELLS PROPERTIES, 18th International Meeting of the European Society of Gynaecological Oncology (ESGO). International Journal of Gynecological Cancer, 2013.


Researcher : Yeung TWY

List of Research Outputs

Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience, Hong Kong Medical Journal. 2014.
Lee V.C.Y., Li R.H.W., Chai J., Yeung T.W.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles, Fertility and Sterility. 2014, 101: 1288-1293.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Serum Level of Sex Hormone-Binding Globulin Is a Good Independent Predictor of Metabolic Syndrome in Women with Polycystic Ovary Syndrome, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo. 2014.
Li T.K.T., Li R.H.W., Yeung T.W.Y., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The Endocrine Disruptor Perflurooctane sulfonate (PFOS) modulates Spheroids attachment onto Endometrial cells through Wnt/-catenin inhibition. P2.21. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong. . 2013.


Researcher : Yeung WSB

Project Title:Role of microRNA let-7 in implantation of mouse blastocysts
Investigator(s):Yeung WSB, Lee CKF, Liu W, Pang RTK
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2011


Project Title:MicroRNA-135a induction transforms normal human papillomarvirus infected cervical cells into cells with cancer stem cell-like properties.
Investigator(s):Yeung WSB, Pang RTK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012
Completion Date:04/2014


Project Title:MicroRNA-135a transforms normal HPV infected cervical cells into cancer cells and cells with cancer stem cell-like properties
Investigator(s):Yeung WSB, Tsao GSW, Ngan HYS, Pang RTK, Cheung ANY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Identification and characterization of label-retaining cells in cervical cancer
Investigator(s):Yeung WSB, Pang RTK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

CAO M., Chan R.W.S. and Yeung W.S.B., Characterization of Mouse Endometrial Labeling Retaining Cells after Uterine Remodeling., 29th European Society of Human Reproduction and Embryology, London, United Kingdom, 1st – 3rd Jul 2013.. 2013.
CHEONG W.Y.A., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation , Regional Best Abstract Award (Southeast Asia) - Society for the Study of Reproduction, USA. 2013.
CHEONG W.Y.A., Pang R.T.K., Liu W., KODITHUWAKKU KANKANAMGE S.P.K., Lee C.K.F. and Yeung W.S.B., MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos , Human Reproduction. 2014, 29: 750-762.
CHEONG W.Y.A., Pang R.T.K., Liu W., Lee C.K.F. and Yeung W.S.B., Up-regulation of Lin28 and Dicer are required for the activation of mouse blastocysts. , SSR's 46th annual meeting reproductive health: Nano to Global, Montreal, Canada. 2013.
Chai J., Yeung T.W.Y., Lee V.C.Y., Li R.H.W., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Live birth rate, multiple pregnancy rate, and obstetric outcomes of elective single and double embryo transfers: Hong Kong experience, Hong Kong Medical Journal. 2014.
Chan R.W.S., Mak A.S., Yeung W.S.B., Lee C.K.F., Cheung A.N.Y., Ngan H.Y.S. and Wong A.S., Human female reproductive tract epithelial cell culture., Methods Mol Biol.. 2013, 945: 347-363.
Cheong A.W.Y., Liu W., Pang R.T.K., Lee C.K.F. and Yeung W.S.B., Concomitant Regulatory Effect of Lin28 and Dicer on MicroRNA Let-7a Expression Alters the State of the Blastocysts During Embryo Implantation. , The 46th Annual Meeting of SSR, 22–26 July 2013, Montréal, Québec, Canada.. 2013.
Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Chiu C.N., WONG S.T., Lee C.L., Lam K.W., WONG H.H.V. and Yeung W.S.B., Control of human trophoblast functions by adrenomedullin, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014.
Guo Y., Lee C.L., SO K.H., Gao J., Yeung W.S.B., Yao Y.Q. and Lee C.K.F., Soluble human leukocyte antigen-g5 activates extracellular signal-regulated protein kinase signaling and stimulates trophoblast invasion, PLoS One. 2013, 8: e76023.
KOTTAWATTA K.S.A., SO K.H., Yeung W.S.B. and Lee C.K.F., Modulation of OLFM1 and CTBP1 Expression via miR-132/-212 in Human Endometrial Epithelial Cells. P2.16. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong.. 2013.
KWAN C.K., Pang R.T.K., LEUNG O.N., YE T., Yeung W.S.B. and Ho P.C., Effects of In-Vitro Culture And Bisphenol A Exposure On DNA Methylation Of Imprinted Genes May Be Obtainable In High Resolution From A Single Mouse Embryo, Society for the Study of Reproduction 2013: 46th General Meeting Reproductive Health: Nano to Global. 2013.
Ko K.Y.J., HUANG W., Li R.H.W., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Chiu C.N., Ten best paper award: An in-vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions., Asian and Oceanic Congress of Obstetrics and Gynaecology, 20-23 October 2013, Bangkok, Thailand, . 2013.
LEUNG O.N., Deng W., Ye T., Ngan H.Y.S., Tsao G.S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Poster Award (Title of poster presentation: In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model), 13th Congress of the European Society of Contraception and Reproductive Health. 2014.
Lee C.L., Li K., Lam K.W., Ng E.H.Y., Koistinen H., Seppala M., Yeung W.S.B. and Chiu C.N., Glycodelin-A treatment reduces the adverse effect of macrophage co-culture on human sperm motility, Molecular reproduction and development. 2014, 81(6): 482-3.
Lee C.L., Chiu C.N., Hautala L., Salo T., Yeung W.S.B., Stenman U.H. and Koistinen H., Human chorionic gonadotropin and its free β-subunit stimulate trophoblast invasion independent of LH/hCG receptor., Molecular and Cellular Endocrinology. 2013, 375(1-2): 43-52.
Lee C.L., LAM P.Y., LAM K.W., LEUNG O.N., Pang R.T.K., Chu I.K., Wan H.L.T., Chai J., Yeung W.S.B. and Chiu C.N., Identification of CD147 (basigin) as a mediator of trophoblast functions. , Human Reproduction. 2013, 28: 2920-2929.
Lee C.L., Guo Y., Yao Y.Q., Yeung W.S.B. and Lee C.K.F., Soluble human leukocyte antigen-G5 stimulates trophoblast invasion via receptor-mediated activation of Extracellular Signal-regulated Protein Kinase Signaling. , P6. The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual scientific meeting, 24 Nov 2013, Hong Kong.. 2013.
Lee C.Y.L., PENG Q., CHEN C.H., Ng E.H.Y. and Yeung W.S.B., Sirtuin 1 interacts with DNA repair molecules during the initiation phase of reprogramming from mouse fibroblasts to mouse induced pluripotent stem cells, ISSCR 12th Annual Meeting. 2014.
Lee V.C.Y., Li R.H.W., Chai J., Yeung T.W.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen–thawed embryo transfer in natural cycles, Fertility and Sterility. 2014, 101: 1288-1293.
Lee V.C.Y., Gao J., Lee C.K.F., Ng E.H.Y., Yeung W.S.B. and Ho P.C., The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta, Hum Reprod. 2013, 28(11): 2912-9.
Leung C.O., Deng W., Ye T.M., Ngan H.Y.S., Tsao S.W., Cheung A.N.Y., Pang R.T.K. and Yeung W.S.B., miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway, Carcinogenesis. 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Cumulative live-birth rate in women with polycystic ovary syndrome or isolated polycystic ovaries undergoing in-vitro fertilisation treatment, Journal of Assisted Reproduction and Genetics. 2014, 31: 205-211.
Li R.H.W., LI T., LI Y., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., In-vitro study on the effect of ulipristal acetate on human embryo implantation using a trophoblastic spheroid and endometrial cell co-culture model, The 13th European Society of Contraception Congress. 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian sensitivity index is an excellent measure of ovarian responsiveness to gonadotrophin stimulation in in-vitro fertilization, The 23rd Asian and Oceanic Congress of Obstetrics and Gynaecology. 2013.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Serum Level of Sex Hormone-Binding Globulin Is a Good Independent Predictor of Metabolic Syndrome in Women with Polycystic Ovary Syndrome, The 16th International Congress of Endocrinology & the Endocrine Society’s 96th Annual Meeting & Expo. 2014.
Li T.K.T., Li R.H.W., Yeung T.W.Y., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The Endocrine Disruptor Perflurooctane sulfonate (PFOS) modulates Spheroids attachment onto Endometrial cells through Wnt/-catenin inhibition. P2.21. , The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 Dec 2013, Hong Kong. . 2013.
O W.S., Li R.H.W., Liao S., Cheung A.N.Y., Ng E.H.Y., Yeung W.S.B., Ho J.C.M. and Tang F., Decreases in adrenomedullin expression and ciliary beat frequency in the nasal epithelium in tubal pregnancy, Fertility and Sterility. 2013, 100: 459-463.e1.
Pang R.T.K., LEUNG O.N., YE T., Ngan H.Y.S., Cheung A.N.Y. and Yeung W.S.B., CERVICAL CANCER CD133 POSITIVE CELLS POSSESS TUMOR INITIATING CELLS PROPERTIES, 18th International Meeting of the European Society of Gynaecological Oncology (ESGO). International Journal of Gynecological Cancer, 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Human chorionic gonadotropin enhances receptivity of Fallopian tube through down-regulation of Olfactomedin-1., The 46th Annual Meeting of SSR, 22–26 July, 2013, Montréal, Québec, Canada.. 2013.
So K.H., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast onto endometrial epithelial cells through activation of ERK and Wnt/beta-catenin signaling pathway. , The 8th International Huaxia Congress of Endocrinology, 21-22 August, 2013, Xi’an, China.. 2013.
So K.H., Lee C.Y.L., Li R.H.W., Yeung W.S.B. and Lee C.K.F., Role of hCG on attachment of trophoblast surrogate onto endometrial/Oviductal epithelial cell monolayer through activation of ERK and Wnt/beta-catenin signaling pathway. OP3., The Hong Kong Society of Endocrinology, Metabolism and Reproduction Annual Scientific Meeting, 24 November, 2013, Hong Kong.. 2013.
TSANG H., CHEUNG T.Y., KODITHUWAKKU KANKANAMGE S.P.K., Chai J., Yeung W.S.B., Wong C.K. and Lee C.K.F., Perfluorooctanoate suppresses spheroid attachment on endometrial epithelial cells through peroxisome proliferator-activated receptor alpha and down-regulation of Wnt signaling, Reprod Toxicol. 2013, 42: 164-71.
Wong B.S., Lam K.K., Lee C.L., WONG H.H.V., Lam M.P., Chu I.K., Yeung W.S.B. and Chiu C.N., Adrenomedullin enhances invasion of human extravillous cytotrophoblast-derived cell lines by regulation of urokinase plasminogen activator expression and s-nitrosylation. (Feb 2013), Biology of Reproduction. 2013, 88(2): 34.
Wu R., Wang Z.P., Fung Y.S., Seah D.Y.P. and Yeung W.S.B., Assessment of adulteration of soybean proteins in dairy products by 2D microchip-CE device, Electrophoresis. 2014, 35: 1728-1734.
Wu R., Wang Z.P., Zhao W., Yeung W.S.B. and Fung Y.S., Multi-dimension Microchip-capillary Electrophoresis Device For Determination Of Functional Proteins In Infant Milk Formula, Journal of Chromatography A. 2013, 1304: 220-226.
Wu R., Wang Z., Zhao W., Yeung W.S.B. and Fung Y.S., Multi-dimension microchip-capillary electrophoresis device for determination of functional proteins in infant milk formula. , J Chromatogr A. . 2013, 1304: 220-226.
YEUNG A.S.-.Y., So K.H., Yeung W.S.B. and Lee C.K.F., Generation of Trs4 knockout mice for spermatogenesis studies. P1.29., The 18th Research Postgraduate Symposium, The University of Hong Kong. 11-12 December, 2013, Hong Kong.. 2013.
Yeung W.S.B., Lee C.K.F., Chiu C.N., Lee C.Y.L. and Pang R.T.K., Interactions between gametes/preimplantation embryos with the female reproductive tract, International Workshop on Women’s Reproductive Health Research, The Ottawa Hospital, Ottawa, Canada, 11-13 April 2014. 2014.


Researcher : Yung MH

List of Research Outputs

Chan D.W., YUNG M.H. and Ngan H.Y.S., MAP30 protein of Momordica charantia functions as a natural AMPK activator in combating tumorigenic and chemoresistant capacities of ovarian cancer, Croucher Advanced Study Institute (ASI): Tumour Microenvironment – Cancer Cell Metabolism. LKS Faculty of Medicine, HKU. 13 November, 2013.. Croucher Advanced Study Institute (ASI), 2013.
Yung M.H., Chan D.W., Liu V.W.S., Yao K.M. and Ngan H.Y.S., Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade, BMC Cancer. 2013, 13: 327.


Researcher : Yung SF

Project Title:A randomized comparative trial to compare the efficacy of vaginal misoprostol moistened with 5% acetic acid with dry vaginal misoprostol in the medical management of first trimester silent miscarriage
Investigator(s):Yung SF, Ho PC, Ng EHY, Lee VCY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2011


Project Title:Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps
Investigator(s):Yung SF, Lee CKF, Ng EHY, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2013


List of Research Outputs

Lai C.W., Yung S.F. and Ng E.H.Y., Endometrial vascularity is lower in pregnancies with pregnancy-induced hypertension or small-for-gestational age in livebirth after IVF, Ultrasound Obstet Gynecol. 2014.


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