Dept of Psychiatry

DEPT OF PSYCHIATRY

Researcher : BASIL P

List of Research Outputs

BASIL P., Li Q., Dempster E.L., Wong P.C., Sham P.C., Mill J. and McAlonan G.M., Dietary intervention on the epigenetic changes induced by environmental risk factors in the adolescent brain, HGM. 2014.

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : Butler WL

List of Research Outputs

Iyegbe C., Campbell D.D., Butler W.L., Ajnakina O. and Sham P.C., The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research, Social Psychiatry and Psychiatric Epidemiology. Springer Berlin Heidelberg, 2014, 49(2): 169-182.

Power R.A., Cohen-woods S., Ng M.Y., Butler W.L. and et al. , Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder., In: Ming T. Tsuang and Stephen V. Faraone, American Journal of Medical Genetics Part B (Neuropsychiatric Genetics). 2013, 162: 521-9.

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : CHAN CWT

List of Research Outputs

CHAN C.W.T., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and predictors of disengagement from a 2-year early intervention program for psychosis in Hong Kong, Schizophrenia Research. 2014, 153 (1-3): 204-208.

CHAN C.W.T., Chang W.C., Gold J.M., Waltz J.A., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Reward learning impairment in patients with first-episode schizophrenia-spectrum disorder, Schizophrenia Research. 2014, 153 (S1): 220.

Researcher : CHAN KSK

List of Research Outputs

Chan K.W., CHAN K.S.K., Hui C.L.M., WONG H.Y.G., Chang W.C., Lee H.M.E., TANG Y.M. and Chen E.Y.H., Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective, Psychiatry Research. 2014, 216 (2): 177-184.

Researcher : CHEN SM

List of Research Outputs

CHEN S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of suicidal behaviours in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow study, Schizophrenia Research. 2014, 153 (S1): 190.

Chang W.C., CHEN S.M., Chan K.W., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Evaluation of a community case-management program for patients with schizophrenia-spectrum disorder: a prospective 1-year case-control study, Schizophrenia Research. 2014, 153 (S1): 185-186.

Chang W.C., Chen S.M., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationships of suicidal ideation with symptoms, neurocognitive function, and psychological factors in patients with first-episode psychosis, Schizophrenia Research. 2014, 157 (1-3_: 12-18.

Researcher : CHOI SC

List of Research Outputs

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : Campbell DD

Project Title:	Whole exome sequencing of trios to identify novel genes implicated in Currarino Syndrome
Investigator(s):	Campbell DD, Tam PKH, Garcia-Barcelo MM, Sham PC, Cherny SS
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2013

List of Research Outputs

Davis L.K., et al. 1., Campbell D.D., et al. 2. and Scharf J.M., Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture, PLoS Genetics. 2013, 9(10).

Dickson H., Cullen A.E., Reichenberg A., Hodgins S., Campbell D.D., Morris R.G. and Laurens K.R., Cognitive impairment among children at-risk for schizophrenia, Journal of Psychiatric Research. 2014, 50: 92-99.

Iyegbe C., Campbell D.D., Butler W.L., Ajnakina O. and Sham P.C., The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research, Social Psychiatry and Psychiatric Epidemiology. Springer Berlin Heidelberg, 2014, 49(2): 169-182.

PORSCH R.M., Merello E., De Marco P., So M.T., Sham P.C., Tam P.K.H., Cherny S.S., Capra V., Garcia-Barcelo M.M. and Campbell D.D., De novo mutations associated with sporadic cases of caudal regression syndrome, European Conference of Human Genetics, Milan, Italy, 31 May - 3 June 2014.

Researcher : Chan CY

Project Title:	The Australasian Marce Society 2013 Conference - Perinatal mental health: from conception to kindergarten. Connecting research to clinical practice.Connecting research to clinical practice; Antenatal Anxiety at the Second Trimester: Risk Factors and Effects on Anxiety and Infant Development at 6-Week Postpartum /Maternal Anxiety across Pregnancy: Prevalence, Pattern and Relations to Postpartum Anxiety
Investigator(s):	Chan CY
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	10/2013
Completion Date:	10/2013

List of Research Outputs

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal Anxiety at the Second Trimester: Risk Factors and Effects on Anxiety and Infant Development at 6-Week Postpartum , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal anxiety in the first trimester: Risk factors and effects on anxiety and depression in the third trimester and 6-week postpartum, Open Journal of Psychiatry. 2013, 3: 301-310.

Koh Y.W., Chan C.Y., Lee A.M. and Tang C.S.K., A study of the relationship between paternal mental health, maternal factors and impact on paternal-fetal attachment: A longitudinal study, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden. Connecting Research to Clinical Practice. 2013.

Koh Y.W., Chan C.Y. and Lee A.M., The Impact of Gender Role and Traditionalism-modernity on Paternal Mental Health Problems among Hong Kong Expectant Fathers: A Longitudinal Study, Poster presentation at the 21st World Congress of Social Psychiatry, The University of Lisbon, Lisbon, Portugal (June 29-July 3, 2013). 2013.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Anxiety during Pregnancy: Prevalence and Its Relations to Postpartum Anxiety , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Depression across Pregnancy: Prevalence, Pattern and Relations to Postpartum Depression, Depression Research and Treatment 2014. 2014.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal anxiety across pregnancy: Prevalence, pattern and relations to postpartum anxiety, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden Connecting Research in Clinical Practice, Melbourne, Australia, October 21, 2013.

Wong G.K.Y., To C.K.S., Lee A.M., Chan C.Y. and Lam G.Y.H., Effect of prenatal maternal depression on early speech sound acquisition, Paper presentation at 9th Asia Pacific Conference on Speech, Language and Hearing, Taiwan. 2013.

Wong K.Y.G., To K.S., Lee A.M., Lam Y.H. and Chan C.Y., Effect of prenatal maternal depression on early speech sound acquisition, Speech, Language, and Hearing.. 2013, Maney Publisher.

Researcher : Chan KW

Project Title:	Social cognition of people with psychosis-like experiences (PLEs): behavioral and functional imaging study
Investigator(s):	Chan KW, Chen EYH, Hui CLM, Wong GHY, Lee HME, Chang WC
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2013

Project Title:	"iPEP (Internet-based psychosis education program)": Web-based self-help psychoeducation program for caregivers of patients with psychosis
Investigator(s):	Chan KW, Chen EYH, Chang WC, Lee HME, Hui CLM, Wong GHY, Tse SSK
Department:	Psychiatry
Source(s) of Funding:	Health Care and Promotion Fund - Research Grant Projects
Start Date:	09/2013

Project Title:	Treatment resistance following the first-episode schizophrenia-spectrum disorder: a retrospective case-control study
Investigator(s):	Chan KW, Chen EYH, Chang WC, Lee HME, Wong GHY, Hui CLM, Sham PC
Department:	Psychiatry
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	04/2014

Project Title:	Psychotic-like experience (PLEs) in the general population of Hong Kong: a two-year prospective follow up study
Investigator(s):	Chan KW, Chen EYH, Chang WC, Lee HME, Wong GHY, Hui CLM, Chan WC
Department:	Psychiatry
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	05/2014

Project Title:	Genetic polymorphism study on association of inflammatory process and development of treatment-resistant schizophrenia (TRS) in Han-Chinese population
Investigator(s):	Chan KW, Chen EYH, Cherny SS, Hui CLM, Lee HME, Chang WC
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2014

List of Research Outputs

CHAN C.W.T., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and predictors of disengagement from a 2-year early intervention program for psychosis in Hong Kong, Schizophrenia Research. 2014, 153 (1-3): 204-208.

CHAN C.W.T., Chang W.C., Gold J.M., Waltz J.A., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Reward learning impairment in patients with first-episode schizophrenia-spectrum disorder, Schizophrenia Research. 2014, 153 (S1): 220.

CHEN S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of suicidal behaviours in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow study, Schizophrenia Research. 2014, 153 (S1): 190.

Chan K.W., SO H.C., Hui C.L.M., Chang W.C., Lee H.M.E., Chung D.W.S., Tso S., Hung S.F., Yip K.C., Dunn E. and Chen E.Y.H., 10-year outcome study of an early intervention program for psychosis compared with standard care service, Psychological Medicine. 2014.

Chan K.W., CHAN K.S.K., Hui C.L.M., WONG H.Y.G., Chang W.C., Lee H.M.E., TANG Y.M. and Chen E.Y.H., Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective, Psychiatry Research. 2014, 216 (2): 177-184.

Chan K.W., Hui C.L.M., WONG H.Y.G., Lee H.M.E., Chang W.C. and Chen E.Y.H., Medication adherence, knowledge about psychosis, and insight among patients with a schizophrenia-spectrum disorder, Journal of Nervous and Mental Disease. 2014, 202 (1): 25-29.

Chang W.C., CHEN S.M., Chan K.W., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Evaluation of a community case-management program for patients with schizophrenia-spectrum disorder: a prospective 1-year case-control study, Schizophrenia Research. 2014, 153 (S1): 185-186.

Chang W.C., Hui C.L.M., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impacts of duration of untreated psychosis on cognition and negative symptoms in first-episode schizophrenia: a 3-year prospective follow-up study, Psychological Medicine. 2013, 43 (9): 1883-1893.

Chang W.C., Chang R., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and Predictors of depressive symptoms in non-affective psychosis patients in Jockey Club Early Psychosis (JCEP) Project in Hong Kong, Schizophrenia Research. 2014, 153 (S1): 267.

Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E., WONG H.Y.G. and Chen E.Y.H., Relationship between diminished expression and cognitive impairment in first-episode schizophrenia: A prospective three-year follow-up study, Schizophrenia Research. 2014, 152 (1): 146-151.

Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Symptomatic remission and cognitive impairment in first-episode schizophrenia: a prospective 3-year follow-up study, Journal of Clinical Psychiatry. 2013, 74 (11): e1046-1053.

Chang W.C., TANG Y.M., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationship of early premorbid adjustment with negative symptoms and cognitive functions in first-episode schizophrenia: a prospective three-year follow-up study, Psychiatry Research. 2013, 209 (3): 353-360.

Chang W.C., Chen S.M., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationships of suicidal ideation with symptoms, neurocognitive function, and psychological factors in patients with first-episode psychosis, Schizophrenia Research. 2014, 157 (1-3_: 12-18.

Chang W.C., Lau E.S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year outcome comparison between patients presenting with first-episode psychotic mania and schizophrenia to easy program in Hong Kong, Schizophrenia Research. 2014, 156 (S1): 304-305.

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013, n/a-n/a.

Hui C.L.M., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Comparing illness presentation, treatment and functioning between patients with early-and adult-onset psychosis, Schizophrenia Research. 2014, 153 (S1): 263-264.

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Hui C.L.M., TANG Y.M., Wong G.H.Y., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Predictors of help-seeking duration in adult-onset psychosis in Hong Kong, Social Psychiatry and Psychiatric Epidemiology. 2013, 48 (11): 1819-1828.

Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Li Y.K., Lee T.M. and Chen E.Y.H., Sexual dysfunction in Chinese patients with first-episode psychosis: prevalence, clinical correlates and functioning, Schizophrenia Research (Letter to the Editor). 2013, 148: 181-182.

LEE K.W., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Persistence of psychotic-like experiences (PLEs) in the general population of Hong Kong, Schizophrenia Research. 2014, 153 (S1): 137.

LEE T.M., Lee H.M.E., Chan K.W. and Chang W.C., Understanding the physical activity behavior among patients with psychosis, Schizophrenia Research. 2014, 153 (S1): 137.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Comparison of characteristics of psychosis patients with and without hospitalization at first episode, Schizophrenia Research. 2014, 153 (S1): 168.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Ching Y.N.E. and Chen E.Y.H., Differential effects of antipsychotics on quality of life and functioning in Chinese patients with first-episode psychosis, Schizophrenia Research. 2014, 153 (S1): 282.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Li Y.K., LEE T.M., Lin J. and Chen E.Y.H., Impact of physical activity on functioning of patients with first-episode psychosis-A 6 months prospective longitudinal study, Schizophrenia Research. 2013, 150 (2): 538-541.

Lin J., Lee H.M.E., Chan K.W., Chang W.C., Su W., Honer W.G., Khong P.L., Tse M.A., Chan C.L.W., So K.F. and Chen E.Y.H., The impacts of aerobic exercise and mind-body exercise (yoga) on neuro-cognition and clinical symptoms in early psychosis: a single-blind randomized controlled clinical trial , Schizophrenia Research. 2014, 153 (S1): 260.

TANG Y.M., Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E., Yeung W.S., Wong C.K., Tang W.N., Chan W.F., Pang E.P.F., Tso S., Ng R.M.K., Hung S.F., Dunn E.L.W., Sham P.C. and Chen E.Y.H., Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study, Schizophrenia Research. 2014, 153 (1-3): 1-8.

Researcher : Chan WC

Project Title:	A validation study of Cantonese version of Apathy Evaluation Scale in cognitively impaired older Chinese
Investigator(s):	Chan WC, Law ACK
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2013

Project Title:	9th Annual General Meeting of Taiwanese Society of Geriatric Psychiatry; Physical activities and the risk of progression to dementia: findings from HK-MAPS (Hong Kong Memory and Ageing Prospective Study)
Investigator(s):	Chan WC
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	03/2014
Completion Date:	03/2014

Project Title:	A randomised controlled trial of home-based exercise intervention for caregivers of persons with dementia
Investigator(s):	Chan WC
Department:	Psychiatry
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	04/2014

List of Research Outputs

Chan W.C., BPSD in Hong Kong: Findings from HK-MAPS , The 16th International Psychogeriatric Association International Congress / International Psychogeriatric Association . 2013.

Chan W.C., Behavioural & psychological symptoms of dementia:a challenge for all , The 16th Asia Pacific Regional Conference of Alzheimer’s Disease International 2013 / Alzheimer’s Disease International, Hong Kong Alzheimer's Disease Association. 2013.

Chan W.C. and Lam P.C.W., Dementia - An 'Old' Disorder with New Perspectives, East Asian Archives of Psychiatry. 2013, 23 (3): 76-77.

Chan W.C., Dementia caregiving: experience, burden and interventions, International Alzheimer’s Disease Conference 2014 / HKU Alzheimer’s Disease Research Network . 2014.

Chan W.C., Early and practical screening of dementia in clinical settings, Novel approach on dementia (major neurocognitive disorders workshop / Hong Kong Alzheimer's Association, Hong Kong Society for Rehabilitation, Hong Kong Occupational Therapist Association. 2014.

Chan W.C., Lam L.C.W., Wong C.H.Y., Leung G.T.Y. and Fung A.W.T., Outstanding Paper Presentation Award, Hong Kong Association of Gerontology. 2013.

Chan W.C., Recent advances in the management of late life depression, Annual Scientific Meeting 2014 / The Federation of Medical Societies of Hong Kong. 2014.

Lam L.C.W., Chan W.C., WONG S.M., Chen E.Y.H., Ng R.M.K., Lee H.M.E., Chang W.C., Hung S.F., CHeung E.F.C., Sham P.C., Chiu H.F.K., Lam M., Chiang T.P., J van O.S., Lau J.T.F., Lewis G., Bebbington P. and The Hong Kong Mental Morbidity Survey Team #., The Hong Kong Mental Morbidity Survey: background and Study Design, East Asian Archives of Psychiatry. 2014, 24 (1): 30-36.

Wong C.H., Leung G.T., Fung A.W., Chan W.C. and Lam L.C., Cognitive predictors for five-year conversion to dementia in a population based sample of Chinese older adults, International Psychogeriatrics. 2013, 25: 1125-1134.

Researcher : Chang WC

Project Title:	Validation of negative symptom scale & investigation of reward learning deficits in first-episode schizophrenia
Investigator(s):	Chang WC, Chen EYH, Lam MLM, Chan KW, Hui CLM, Wong GHY
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2011

Project Title:	Reward learning impairment in clinical high-risk individuals, first-episode psychosis patients and their non-psychotic siblings: psychosis prediction and endophenotypic investigation
Investigator(s):	Chang WC, Lee HME, Wong GHY, Chan KW, Hui CLM, Chen EYH
Department:	Psychiatry
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2014

Project Title:	4th Schizophrenia International Research Society Conference; "Evaluation of a community case“management program for patients with schizophrenia-spectrum disorder: a prospective 1-year case-control study/Prevalence and predictors of depressive symptoms in non-affective psychosis patients in Jockey Club Early Psychosis (JCEP) Project in Hong Kong/Three-year outcome comparison between patients presenting with first-episode psychotic mania and schizophrenia to EASY program in Hong Kong
Investigator(s):	Chang WC
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	04/2014
Completion Date:	04/2014

Project Title:	An fMRI study on disrupted sense of agency in psychosis patients in term of decision making dysfluency
Investigator(s):	Chang WC, Chen EYH
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	05/2014

List of Research Outputs

CHAN C.W.T., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and predictors of disengagement from a 2-year early intervention program for psychosis in Hong Kong, Schizophrenia Research. 2014, 153 (1-3): 204-208.

CHAN C.W.T., Chang W.C., Gold J.M., Waltz J.A., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Reward learning impairment in patients with first-episode schizophrenia-spectrum disorder, Schizophrenia Research. 2014, 153 (S1): 220.

CHEN S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of suicidal behaviours in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow study, Schizophrenia Research. 2014, 153 (S1): 190.

Chan K.W., SO H.C., Hui C.L.M., Chang W.C., Lee H.M.E., Chung D.W.S., Tso S., Hung S.F., Yip K.C., Dunn E. and Chen E.Y.H., 10-year outcome study of an early intervention program for psychosis compared with standard care service, Psychological Medicine. 2014.

Chan K.W., CHAN K.S.K., Hui C.L.M., WONG H.Y.G., Chang W.C., Lee H.M.E., TANG Y.M. and Chen E.Y.H., Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective, Psychiatry Research. 2014, 216 (2): 177-184.

Chan K.W., Hui C.L.M., WONG H.Y.G., Lee H.M.E., Chang W.C. and Chen E.Y.H., Medication adherence, knowledge about psychosis, and insight among patients with a schizophrenia-spectrum disorder, Journal of Nervous and Mental Disease. 2014, 202 (1): 25-29.

Chang W.C., Clinical Research Fellowship (granted by Research General Council RGC). 2014.

Chang W.C., Epidemiological study of psychosis in HKMMS, Presented in the HK Schizophrenia Research Society Scientific Symposium, May 3, 2014. 2014.

Chang W.C., CHEN S.M., Chan K.W., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Evaluation of a community case-management program for patients with schizophrenia-spectrum disorder: a prospective 1-year case-control study, Schizophrenia Research. 2014, 153 (S1): 185-186.

Chang W.C., Hui C.L.M., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impacts of duration of untreated psychosis on cognition and negative symptoms in first-episode schizophrenia: a 3-year prospective follow-up study, Psychological Medicine. 2013, 43 (9): 1883-1893.

Chang W.C., Chang R., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and Predictors of depressive symptoms in non-affective psychosis patients in Jockey Club Early Psychosis (JCEP) Project in Hong Kong, Schizophrenia Research. 2014, 153 (S1): 267.

Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E., WONG H.Y.G. and Chen E.Y.H., Relationship between diminished expression and cognitive impairment in first-episode schizophrenia: A prospective three-year follow-up study, Schizophrenia Research. 2014, 152 (1): 146-151.

Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Symptomatic remission and cognitive impairment in first-episode schizophrenia: a prospective 3-year follow-up study, Journal of Clinical Psychiatry. 2013, 74 (11): e1046-1053.

Chang W.C., TANG Y.M., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationship of early premorbid adjustment with negative symptoms and cognitive functions in first-episode schizophrenia: a prospective three-year follow-up study, Psychiatry Research. 2013, 209 (3): 353-360.

Chang W.C., Chen S.M., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationships of suicidal ideation with symptoms, neurocognitive function, and psychological factors in patients with first-episode psychosis, Schizophrenia Research. 2014, 157 (1-3_: 12-18.

Chang W.C., Lau E.S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year outcome comparison between patients presenting with first-episode psychotic mania and schizophrenia to easy program in Hong Kong, Schizophrenia Research. 2014, 156 (S1): 304-305.

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013, n/a-n/a.

Hui C.L.M., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Comparing illness presentation, treatment and functioning between patients with early-and adult-onset psychosis, Schizophrenia Research. 2014, 153 (S1): 263-264.

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Hui C.L.M., TANG Y.M., Wong G.H.Y., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Predictors of help-seeking duration in adult-onset psychosis in Hong Kong, Social Psychiatry and Psychiatric Epidemiology. 2013, 48 (11): 1819-1828.

Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Li Y.K., Lee T.M. and Chen E.Y.H., Sexual dysfunction in Chinese patients with first-episode psychosis: prevalence, clinical correlates and functioning, Schizophrenia Research (Letter to the Editor). 2013, 148: 181-182.

LEE K.W., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Persistence of psychotic-like experiences (PLEs) in the general population of Hong Kong, Schizophrenia Research. 2014, 153 (S1): 137.

LEE T.M., Lee H.M.E., Chan K.W. and Chang W.C., Understanding the physical activity behavior among patients with psychosis, Schizophrenia Research. 2014, 153 (S1): 137.

Lam L.C.W., Chan W.C., WONG S.M., Chen E.Y.H., Ng R.M.K., Lee H.M.E., Chang W.C., Hung S.F., CHeung E.F.C., Sham P.C., Chiu H.F.K., Lam M., Chiang T.P., J van O.S., Lau J.T.F., Lewis G., Bebbington P. and The Hong Kong Mental Morbidity Survey Team #., The Hong Kong Mental Morbidity Survey: background and Study Design, East Asian Archives of Psychiatry. 2014, 24 (1): 30-36.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Comparison of characteristics of psychosis patients with and without hospitalization at first episode, Schizophrenia Research. 2014, 153 (S1): 168.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Ching Y.N.E. and Chen E.Y.H., Differential effects of antipsychotics on quality of life and functioning in Chinese patients with first-episode psychosis, Schizophrenia Research. 2014, 153 (S1): 282.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Li Y.K., LEE T.M., Lin J. and Chen E.Y.H., Impact of physical activity on functioning of patients with first-episode psychosis-A 6 months prospective longitudinal study, Schizophrenia Research. 2013, 150 (2): 538-541.

Lin J., Lee H.M.E., Chan K.W., Chang W.C., Su W., Honer W.G., Khong P.L., Tse M.A., Chan C.L.W., So K.F. and Chen E.Y.H., The impacts of aerobic exercise and mind-body exercise (yoga) on neuro-cognition and clinical symptoms in early psychosis: a single-blind randomized controlled clinical trial , Schizophrenia Research. 2014, 153 (S1): 260.

TANG Y.M., Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E., Yeung W.S., Wong C.K., Tang W.N., Chan W.F., Pang E.P.F., Tso S., Ng R.M.K., Hung S.F., Dunn E.L.W., Sham P.C. and Chen E.Y.H., Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study, Schizophrenia Research. 2014, 153 (1-3): 1-8.

Researcher : Chen EYH

Project Title:	10th Biennial Winter Workshop on Schizophrenia N400 and P600 Event-Related Potential Responses to Neutral and Affect-laden Semantic Stimulus in Schizophrenic Patients 2) Predictors of Short-term Functional Outcome Following First Episode Psychosis 3) spontaneous Blink Rate in First-episode Schi Predictors of Short-term Functional Outcome Following First Episode Psychosis Spontaneous Blink Rate in First-episode Schizophrenic Patients: a Prospective Follow-up Study and Temporal Evolution of Extra-pyramidal Side-effects to Conventional Anti-psychotic Medications in First-episode Psychosis
Investigator(s):	Chen EYH
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	02/2000

Project Title:	The Impacts of Yoga and Exercise on Neuro-cognitive Function and Symptoms in Early Psychosis - A single-blinded randomized controlled clinical trial
Investigator(s):	Chen EYH, Chiu CPY, Tse MA, Khong PL, Lee TMC, Chan CLW, So KF
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	03/2011

Project Title:	The Impacts of Yoga and Aerobic Exercise on Neuro-cognitive Function and Brain Structure in Early Psychosis - A Randomized Controlled Clinical Trial
Investigator(s):	Chen EYH, Chan CLW, Chan KW, Chang WC, Chiu CPY, Honer WG, Khong PL, Lam MLM, Sham PC, So KF, Tse MA
Department:	Psychiatry
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	10/2012

Project Title:	The impact of early medication discontinuation on long-term clinical outcome in first episode psychosis
Investigator(s):	Chen EYH, Hui CLM, Chang WC, Chan KW, Lee HME
Department:	Psychiatry
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	03/2013

Project Title:	fMRI investigation of verbal Information disclosure/non-disclosure in schizophrenic patients and healthy controls
Investigator(s):	Chen EYH, Wong GHY, Hui CLM, Lee HME, Chang WC, Chan KW
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	05/2013

Project Title:	Five-year follow-up of a randomized controlled trial of the duration of early intervention for psychosis: 2 years vs. 3 years
Investigator(s):	Chen EYH, Hui CLM, Wong GHY, Chang WC, Chan KW, Lee HME
Department:	Psychiatry
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	01/2014

Project Title:	4th Schizophrenia International Research Society Conference; Yoga exercise for cognitive impairment in psychotic disorders
Investigator(s):	Chen EYH
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	04/2014

List of Research Outputs

CHAN C.W.T., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and predictors of disengagement from a 2-year early intervention program for psychosis in Hong Kong, Schizophrenia Research. 2014, 153 (1-3): 204-208.

CHAN C.W.T., Chang W.C., Gold J.M., Waltz J.A., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Reward learning impairment in patients with first-episode schizophrenia-spectrum disorder, Schizophrenia Research. 2014, 153 (S1): 220.

CHEN S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of suicidal behaviours in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow study, Schizophrenia Research. 2014, 153 (S1): 190.

Chan K.W., SO H.C., Hui C.L.M., Chang W.C., Lee H.M.E., Chung D.W.S., Tso S., Hung S.F., Yip K.C., Dunn E. and Chen E.Y.H., 10-year outcome study of an early intervention program for psychosis compared with standard care service, Psychological Medicine. 2014.

Chan K.W., CHAN K.S.K., Hui C.L.M., WONG H.Y.G., Chang W.C., Lee H.M.E., TANG Y.M. and Chen E.Y.H., Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective, Psychiatry Research. 2014, 216 (2): 177-184.

Chan K.W., Hui C.L.M., WONG H.Y.G., Lee H.M.E., Chang W.C. and Chen E.Y.H., Medication adherence, knowledge about psychosis, and insight among patients with a schizophrenia-spectrum disorder, Journal of Nervous and Mental Disease. 2014, 202 (1): 25-29.

Chang W.C., CHEN S.M., Chan K.W., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Evaluation of a community case-management program for patients with schizophrenia-spectrum disorder: a prospective 1-year case-control study, Schizophrenia Research. 2014, 153 (S1): 185-186.

Chang W.C., Hui C.L.M., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impacts of duration of untreated psychosis on cognition and negative symptoms in first-episode schizophrenia: a 3-year prospective follow-up study, Psychological Medicine. 2013, 43 (9): 1883-1893.

Chang W.C., Chang R., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and Predictors of depressive symptoms in non-affective psychosis patients in Jockey Club Early Psychosis (JCEP) Project in Hong Kong, Schizophrenia Research. 2014, 153 (S1): 267.

Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E., WONG H.Y.G. and Chen E.Y.H., Relationship between diminished expression and cognitive impairment in first-episode schizophrenia: A prospective three-year follow-up study, Schizophrenia Research. 2014, 152 (1): 146-151.

Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Symptomatic remission and cognitive impairment in first-episode schizophrenia: a prospective 3-year follow-up study, Journal of Clinical Psychiatry. 2013, 74 (11): e1046-1053.

Chang W.C., TANG Y.M., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationship of early premorbid adjustment with negative symptoms and cognitive functions in first-episode schizophrenia: a prospective three-year follow-up study, Psychiatry Research. 2013, 209 (3): 353-360.

Chang W.C., Chen S.M., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationships of suicidal ideation with symptoms, neurocognitive function, and psychological factors in patients with first-episode psychosis, Schizophrenia Research. 2014, 157 (1-3_: 12-18.

Chang W.C., Lau E.S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year outcome comparison between patients presenting with first-episode psychotic mania and schizophrenia to easy program in Hong Kong, Schizophrenia Research. 2014, 156 (S1): 304-305.

Chen E.Y.H., Editorial Board, Clinical Psychopharmacology and Neuroscience. 2014.

Chen E.Y.H., Editorial Board, Schizophrenia Research. 2014.

Chen E.Y.H., Member of the Scientific Advisory Board, European Union. 2014.

FUNG C.M.G., Cheung C., Chen E.Y.H., Lam C.A.R.M.E.N., Chiu C.I.N.D.Y., Law C.H.I.-.W.I.N.G., Leung M.K., Deng M.I.C.H.E.L.L.E., Cheung V.I.N.C.I., Li Q., YAO N., Tai K.S., Yip L.A.W.R.A.N.C.E., Suckling J.O.H.N., Sham P.C., McAlonan G.M. and Chua S.E., MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes, Neuropsychobiology. 2014, 69 (4): 243-248.

Ho R.T.H., Chan K.P.C., Lo H.Y.P. and Chen E.Y.H., Spirituality in Schizophrenia: do patients and healthcare professionals have similar understanding?, 22nd European Congress of Psychiatry. 2014.

Ho R.T.H., Wan H.Y.A., Lo H.Y.P., Au Yeung F.S.W. and Chen E.Y.H., Tai-chi Exercises for Schizophrenia, 22nd European Congress of Psychiatry. 2014.

Ho R.T.H., Potash J.S., Ho A.H.Y., Chen E.Y.H. and Ho F.L.V., Using the Arts to Increase understanding and support for People Living with Mental Illness. . Centre on Behavioral Health, The University of Hong Kong., 2013.

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013, n/a-n/a.

Hui C.L.M., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Comparing illness presentation, treatment and functioning between patients with early-and adult-onset psychosis, Schizophrenia Research. 2014, 153 (S1): 263-264.

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Hui C.L.M., TANG Y.M., Wong G.H.Y., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Predictors of help-seeking duration in adult-onset psychosis in Hong Kong, Social Psychiatry and Psychiatric Epidemiology. 2013, 48 (11): 1819-1828.

Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Li Y.K., Lee T.M. and Chen E.Y.H., Sexual dysfunction in Chinese patients with first-episode psychosis: prevalence, clinical correlates and functioning, Schizophrenia Research (Letter to the Editor). 2013, 148: 181-182.

LEE K.W., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Persistence of psychotic-like experiences (PLEs) in the general population of Hong Kong, Schizophrenia Research. 2014, 153 (S1): 137.

Lam L.C.W., Chan W.C., WONG S.M., Chen E.Y.H., Ng R.M.K., Lee H.M.E., Chang W.C., Hung S.F., CHeung E.F.C., Sham P.C., Chiu H.F.K., Lam M., Chiang T.P., J van O.S., Lau J.T.F., Lewis G., Bebbington P. and The Hong Kong Mental Morbidity Survey Team #., The Hong Kong Mental Morbidity Survey: background and Study Design, East Asian Archives of Psychiatry. 2014, 24 (1): 30-36.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Comparison of characteristics of psychosis patients with and without hospitalization at first episode, Schizophrenia Research. 2014, 153 (S1): 168.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Ching Y.N.E. and Chen E.Y.H., Differential effects of antipsychotics on quality of life and functioning in Chinese patients with first-episode psychosis, Schizophrenia Research. 2014, 153 (S1): 282.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Li Y.K., LEE T.M., Lin J. and Chen E.Y.H., Impact of physical activity on functioning of patients with first-episode psychosis-A 6 months prospective longitudinal study, Schizophrenia Research. 2013, 150 (2): 538-541.

Leung M.C., Stone W.S., Lee H.M.E., Seidman L.J. and Chen E.Y.H., Impaired facilitation of self-control cognition by glucose in patients with schizophrenia: A randomized controlled study, Schizophrenia Research. 2014, 156 (1): 38-45.

Lin J., Lee H.M.E. and Chen E.Y.H., HKU study reveals yoga improves neurocognitive functions in early psychosis, Press release of HKU, 2014.

Lin J., Lee H.M.E., Chan K.W., Chang W.C., Su W., Honer W.G., Khong P.L., Tse M.A., Chan C.L.W., So K.F. and Chen E.Y.H., The impacts of aerobic exercise and mind-body exercise (yoga) on neuro-cognition and clinical symptoms in early psychosis: a single-blind randomized controlled clinical trial , Schizophrenia Research. 2014, 153 (S1): 260.

TANG Y.M., Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E., Yeung W.S., Wong C.K., Tang W.N., Chan W.F., Pang E.P.F., Tso S., Ng R.M.K., Hung S.F., Dunn E.L.W., Sham P.C. and Chen E.Y.H., Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study, Schizophrenia Research. 2014, 153 (1-3): 1-8.

Tam W.W.Y. and Chen E.Y.H., Cognitive Behavioral Case Management (CBCM) for Early Psychosis: A Hong Kong Experience, Advances in Psychology Research. 2013, 97: 117-131.

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : Chen RYL

List of Research Outputs

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : Chen SM

List of Research Outputs

Researcher : Cherny SS

Project Title:	Variance components models for mapping QTLs
Investigator(s):	Cherny SS, Sham PC
Department:	Psychiatry
Source(s) of Funding:	National Institutes of Health, US Department of Health and Human Services - General Award
Start Date:	09/2006

Project Title:	Exome sequencing of mesial temporal lobe epilepsy with hippocampal sclerosis in parent-offspring trios
Investigator(s):	Cherny SS, Sham PC
Department:	Psychiatry
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2013

Project Title:	Annual Meeting of the American Society of Human Genetics; Influence of Alzheimer’s disease genes on cognitive decline: the Guangzhou Biobank Cohort Study
Investigator(s):	Cherny SS
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	10/2013
Completion Date:	10/2013

Project Title:	Do de novo chromosomal abnormalities lead to sporadic biliary atresia?
Investigator(s):	Cherny SS, Garcia-Barcelo MM, Tam PKH
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2014

List of Research Outputs

CHENG G., Tang S.M., Wong H.M.E., Cheng W.C., So M.T., Miao X., ZHANG R., CUI L., Liu X., Ngan E.S.W., Lui V.C.H., Chung H.Y., Chan I.H.Y., Liu J.C., Zhong W., Xia H.M., Yu J.K., Qiu X., Wu X.Z., Wang B., Dong X., Tou J.F., Huang L.M., Yi B., Ren H.X., Chan E.K.W., Ye K., O'Reilly P.F., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Common genetic variants regulating ADD3 gene expression alter biliary atresia risk, Journal of Hepatology. 2013, 59(6): 1285-1291.

Cherny S.S., GUI H., Jiang C.Q., Sham P.C., Xu L., Liu B., Jin Y.L., Zhu T., Zhang W.S., Thomas G.N., Cheng K.K. and Lam T.H., Influence of Alzheimer's disease genes on cognitive decline: the Guangzhou Biobank Cohort Study, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 1190W, Boston, Massachusetts, October 23, 2013.

Haerian B.S., Baum L., Kwan P., Cherny S.S., Tan H.J., Raymond A.A. and Mohamed Z., Association of GABRG2 rs211037 polymorphism with susceptibility to epilepsy in Asians: a multicenter cohort study and meta-analysis, The FASEB Journal. 2014, 28 (1).

Ip D.K.M., Cherny S.S., Leung G.M. and Cowling B.J., Host genetic factors as determinants on immunologic and adverse response on influenza vaccination in human. (Abstract and poster presentation), Options for the Control of Influenza VIII, 5-10 September 2013, Cape Town, South Africa. isirv, 2013.

PORSCH R.M., Merello E., De Marco P., So M.T., Sham P.C., Tam P.K.H., Cherny S.S., Capra V., Garcia-Barcelo M.M. and Campbell D.D., De novo mutations associated with sporadic cases of caudal regression syndrome, European Conference of Human Genetics, Milan, Italy, 31 May - 3 June 2014.

Song Y., Karasugi T., Cheung K.M.C., Chiba K., Ho D.W.H., Miyake A., Kao P.Y.P., Sze K.L., Yee F.Y.A., Takahashi A., Kawaguchi Y., Mikami Y., Matsumoto M., Togawa D., Kanayama M., Shi D., Dai J., Jiang Q., Wu C., Tian W., Wang N., Leong J.C.Y., Luk K.D.K., Yip S.P., Cherny S.S., Wang J.J., Mundlos S., Kelempisioti A., Eskola P.J., Mannikko M., Makela P., Karppinen J., Jarvelin M.R., O'Reilly P.F., Kubo M., Kimura T., Kubo T., Toyoma Y., Mizuta H., Cheah K.S.E., Tsunoda T., Sham P.C., Ikegawa S. and Chan D., Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant., J. Clin. Invest . 2013, 123: 4909-4917.

Tang S.M., WONG H.M.E., GUI H., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Comprehensive comparison of copy number variations detection using Illumina Omni 2.5M and Affymetrix CytoScan arrays, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 552T, Boston, Massachusetts, October 24, 2013.

WONG H.M.E., NG C.L., Lui V.C.H., So M.T., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Gene network analysis of candidate loci for human anorectal malformations. , PLoS One . 2013, 8(8): e69142.

WONG H.M.E., Ng C.L., Lui V.C.H., So M.T., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Gene network analysis of candidate loci for human anorectal malformations, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 1027T. Boston, Massachusetts, October 24, 2013.

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.

Zhang X.W., Sham P.C., Cherny S.S., Meng H.Q., Fu Y.X., Huang Y. and Li T., Parents and teachers report on different aspect[s] of children's and adolescent's conduct disorder and hyperactivity/inattention behavior, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 1255F, Boston, Massachusetts, October 25, 2013.

Researcher : Cheung C

Project Title:	A single cohort prospective MRI study of symptoms and brain structure maturation in autism
Investigator(s):	Cheung C, McAlonan GM, Chua SE, Sham PC
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	12/2008

List of Research Outputs

Cheung C., Drug abuse and the developing brain, The Mental Health Association of Hong Kong, Volunteer Training Camp. 2013.

FUNG C.M.G., Cheung C., Chen E.Y.H., Lam C.A.R.M.E.N., Chiu C.I.N.D.Y., Law C.H.I.-.W.I.N.G., Leung M.K., Deng M.I.C.H.E.L.L.E., Cheung V.I.N.C.I., Li Q., YAO N., Tai K.S., Yip L.A.W.R.A.N.C.E., Suckling J.O.H.N., Sham P.C., McAlonan G.M. and Chua S.E., MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes, Neuropsychobiology. 2014, 69 (4): 243-248.

Researcher : Chiang TP

List of Research Outputs

Lam L.C.W., Chan W.C., WONG S.M., Chen E.Y.H., Ng R.M.K., Lee H.M.E., Chang W.C., Hung S.F., CHeung E.F.C., Sham P.C., Chiu H.F.K., Lam M., Chiang T.P., J van O.S., Lau J.T.F., Lewis G., Bebbington P. and The Hong Kong Mental Morbidity Survey Team #., The Hong Kong Mental Morbidity Survey: background and Study Design, East Asian Archives of Psychiatry. 2014, 24 (1): 30-36.

Researcher : Ching YNE

List of Research Outputs

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Ching Y.N.E. and Chen E.Y.H., Differential effects of antipsychotics on quality of life and functioning in Chinese patients with first-episode psychosis, Schizophrenia Research. 2014, 153 (S1): 282.

Researcher : Chiu CPY

Project Title:	Paternal age effect on the outcome of first episode psychosis
Investigator(s):	Chiu CPY, Chen EYH, Lam MLM, Chan KW, Hui CLM
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2009

List of Research Outputs

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Researcher : Chua SE

Project Title:	King's/HKU Fellowship Awards 2010-11
Investigator(s):	Chua SE
Department:	Psychiatry
Source(s) of Funding:	King's/HKU Fellowship Awards
Start Date:	09/2010

List of Research Outputs

FUNG C.M.G., Cheung C., Chen E.Y.H., Lam C.A.R.M.E.N., Chiu C.I.N.D.Y., Law C.H.I.-.W.I.N.G., Leung M.K., Deng M.I.C.H.E.L.L.E., Cheung V.I.N.C.I., Li Q., YAO N., Tai K.S., Yip L.A.W.R.A.N.C.E., Suckling J.O.H.N., Sham P.C., McAlonan G.M. and Chua S.E., MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes, Neuropsychobiology. 2014, 69 (4): 243-248.

LI T.H., Yao N., Chua S.E., Ho S.L., Khong P.L. and Mak H.K.F., Li DTH, Yao N, Chua S, Ho SL, Khong PL, Mak HKF. Brain Iron Deposition in Parkinson’s Disease by High Resolution Susceptibility MR Phase Imaging. , 20th World Congress of Parkinson's Disease. 2013.

Lam S.S.Y., Wakuda T., Li Q., WEI R., ZHANG X., Chua S.E., Sham P.C., Takei N. and McAlonan G.M., Altered Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Autism, HUPO 2013.

Researcher : Chung KF

Project Title:	Seizure threshold of unilateral electroconvulsive therapy
Investigator(s):	Chung KF, Wong SJ
Department:	Psychiatry
Source(s) of Funding:	Other Funding Scheme
Start Date:	07/2001

Project Title:	Influence of a psychiatric clerkship on medical students' attitudes toward psychiatry and mental patients
Investigator(s):	Chung KF
Department:	Psychiatry
Source(s) of Funding:	Other Funding Scheme
Start Date:	01/2002

Project Title:	Response to moderately suprathreshold unilateral (UL) electroconvulsive therapy (ECT): an examination of possible predictors
Investigator(s):	Chung KF, Irwin MG
Department:	Psychiatry
Source(s) of Funding:	Other Funding Scheme
Start Date:	06/2002

Project Title:	Combined Electroacupuncture and Auricular Acupuncture for Primary Insomnia: A Randomized Controlled Trial of Dose-Response Effect
Investigator(s):	Chung KF, Zhang Z, Yeung WF
Department:	Psychiatry
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	01/2013

Project Title:	Validity and Reliability of the Chinese Version of the Brief Insomnia Questionnaire
Investigator(s):	Chung KF, Yeung WF
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2013
Completion Date:	06/2014

Project Title:	Validity and Reliability of the Chinese Version of the Brief Insomnia Questionnaire (BIQ) in Adolescents
Investigator(s):	Chung KF, Yeung WF
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2014

List of Research Outputs

Chung K.F., Yeung W.F., Yu Y.M., Yung K.P., Zhang S.P., Wong M.T., Lee W.K. and Chan L.W., Acupuncture for residual insomnia associated with major depressive disorder: a placebo- and sham-controlled, subject- and assessor-blind, randomized trial, Journal of Clinical Psychiatry . 2014, accepted..

Chung K.F., Asia-Pacific Psychiatry (Editorial Board, since 2014). 2014.

Chung K.F., Yu Y.M.B., YUNG K.P., Yeung W.F., NG H.Y. and HO Y.Y.F., Assessment of fatigue using the Multidimensional Fatigue Inventory in patients with major depressive disorder, Comprehensive Psychiatry. 2014.

Chung K.F., Chinese Journal of Behavioral Medicine and Brain Science (Editorial Board, 2014-2018). 2014.

Chung K.F., Evidence-Based Complementary and Alternative Medicine (Issue Editor, 2014). 2014.

Chung K.F., Kan K.K.K. and Yeung W.F., Insomnia in adolescents: prevalence, help-seeking behaviors, and types of interventions, Child and Adolescent Mental Health. 2014, 19 (1): 57-63.

Chung K.F., Yeung W.F., HO Y.Y.F., Ho L.M. and YUNG K.P., Validity and reliability of the Brief Insomnia Questionnaire in the general population in Hong Kong, Journal of Psychiatric Research. 2014, 76 (5): 374-379.

Gadau M., Yeung W.F., Liu H., Zaslawski C., Tan Y.S., Wang F.C., Bangrazi S., Chung K.F., Bian Z.X. and Zhang S.P., Acupuncture and moxibustion for lateral elbow pain: a systematic review of randomized controlled trials, BMC Complementary and Alternative Medicine. 2014, 14.

Tse S., Davidson L., Chung K.F., Ng K.L. and Yu C.H., Differences and similarities between functional and personal recovery in an Asian population: a cluster analytic approach, Psychiatry. 2014, 77 (1): 41-56.

Tse S., Murray G., Chung K.F., Davidson L., Ng K.L. and Yu C.H., Exploring the recovery concept in bipolar disorder: a decision tree analysis of psychosocial correlates of recovery stages, Bipolar Disorders. 2014.

Tse S., Davidson L., Chung K.F., Yu C.H., Ng K.L. and Tsoi E., Logistic regression analysis of psychosocial correlates associated with recovery from schizophrenia in a Chinese community, International Journal of Social Psychiatry. 2014.

Tse S.S.K., Murray G., Chung K.F., Davidson L., Ng K.L.J. and Yu C.H., Exploring the recovery concept in bipolar disorder: A decision tree analysis of psychosocial correlates of recovery stages, Bipolar Disorders. 2014, 16: 366-377.

Yeung W.F., Chung K.F., Ng K.Y., Yu Y.M.B., Ziea E.T.C. and Ng B.F.L., A Systematic Review on the Efficacy, Safety and Types of Chinese Herbal Medicine for Depression, Journal of Psychiatric Research. 2014.

Yeung W.F., Chung K.F., Ng K.Y., Yu Y.M.B., Ziea E.T.C. and Ng B.F.L., A meta-analysis of the efficacy and safety of traditional Chinese medicine formula Ganmai Dazao decoction for depression, Journal of Ethnopharmacology. 2014, 153 (2): 309-317.

Yeung W.F., Chen H., Chung K.F. and Zhang Z., Clinical trials of traditional Chinese medicine for insomnia: current status and future directions, World Journal of Sleep Medicine. 2014, 1: 54-58.

Yeung W.F., Chung K.F., YUNG K.P. and NG H.Y., Doxepin for Insomnia: A Systematic Review of Randomized Placebo-controlled Trials, Sleep Medicine Reviews. 2014.

Researcher : FUNG CMG

List of Research Outputs

FUNG C.M.G., Cheung C., Chen E.Y.H., Lam C.A.R.M.E.N., Chiu C.I.N.D.Y., Law C.H.I.-.W.I.N.G., Leung M.K., Deng M.I.C.H.E.L.L.E., Cheung V.I.N.C.I., Li Q., YAO N., Tai K.S., Yip L.A.W.R.A.N.C.E., Suckling J.O.H.N., Sham P.C., McAlonan G.M. and Chua S.E., MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes, Neuropsychobiology. 2014, 69 (4): 243-248.

Researcher : GUI H

List of Research Outputs

Cherny S.S., GUI H., Jiang C.Q., Sham P.C., Xu L., Liu B., Jin Y.L., Zhu T., Zhang W.S., Thomas G.N., Cheng K.K. and Lam T.H., Influence of Alzheimer's disease genes on cognitive decline: the Guangzhou Biobank Cohort Study, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 1190W, Boston, Massachusetts, October 23, 2013.

Tang S.M., WONG H.M.E., GUI H., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Comprehensive comparison of copy number variations detection using Illumina Omni 2.5M and Affymetrix CytoScan arrays, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 552T, Boston, Massachusetts, October 24, 2013.

Researcher : HO YYF

List of Research Outputs

Chung K.F., Yu Y.M.B., YUNG K.P., Yeung W.F., NG H.Y. and HO Y.Y.F., Assessment of fatigue using the Multidimensional Fatigue Inventory in patients with major depressive disorder, Comprehensive Psychiatry. 2014.

Chung K.F., Yeung W.F., HO Y.Y.F., Ho L.M. and YUNG K.P., Validity and reliability of the Brief Insomnia Questionnaire in the general population in Hong Kong, Journal of Psychiatric Research. 2014, 76 (5): 374-379.

Researcher : Hui CLM

Project Title:	4th Biennial Schizophrenia International Research Society Conference; Comparing Illness Presentation, Treatment and Functioning between Patients with Early- and Adult-onset Psychosis
Investigator(s):	Hui CLM
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	04/2014

List of Research Outputs

CHAN C.W.T., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and predictors of disengagement from a 2-year early intervention program for psychosis in Hong Kong, Schizophrenia Research. 2014, 153 (1-3): 204-208.

CHAN C.W.T., Chang W.C., Gold J.M., Waltz J.A., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Reward learning impairment in patients with first-episode schizophrenia-spectrum disorder, Schizophrenia Research. 2014, 153 (S1): 220.

CHEN S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of suicidal behaviours in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow study, Schizophrenia Research. 2014, 153 (S1): 190.

Chan K.W., SO H.C., Hui C.L.M., Chang W.C., Lee H.M.E., Chung D.W.S., Tso S., Hung S.F., Yip K.C., Dunn E. and Chen E.Y.H., 10-year outcome study of an early intervention program for psychosis compared with standard care service, Psychological Medicine. 2014.

Chan K.W., CHAN K.S.K., Hui C.L.M., WONG H.Y.G., Chang W.C., Lee H.M.E., TANG Y.M. and Chen E.Y.H., Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective, Psychiatry Research. 2014, 216 (2): 177-184.

Chan K.W., Hui C.L.M., WONG H.Y.G., Lee H.M.E., Chang W.C. and Chen E.Y.H., Medication adherence, knowledge about psychosis, and insight among patients with a schizophrenia-spectrum disorder, Journal of Nervous and Mental Disease. 2014, 202 (1): 25-29.

Chang W.C., CHEN S.M., Chan K.W., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Evaluation of a community case-management program for patients with schizophrenia-spectrum disorder: a prospective 1-year case-control study, Schizophrenia Research. 2014, 153 (S1): 185-186.

Chang W.C., Hui C.L.M., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impacts of duration of untreated psychosis on cognition and negative symptoms in first-episode schizophrenia: a 3-year prospective follow-up study, Psychological Medicine. 2013, 43 (9): 1883-1893.

Chang W.C., Chang R., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and Predictors of depressive symptoms in non-affective psychosis patients in Jockey Club Early Psychosis (JCEP) Project in Hong Kong, Schizophrenia Research. 2014, 153 (S1): 267.

Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E., WONG H.Y.G. and Chen E.Y.H., Relationship between diminished expression and cognitive impairment in first-episode schizophrenia: A prospective three-year follow-up study, Schizophrenia Research. 2014, 152 (1): 146-151.

Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Symptomatic remission and cognitive impairment in first-episode schizophrenia: a prospective 3-year follow-up study, Journal of Clinical Psychiatry. 2013, 74 (11): e1046-1053.

Chang W.C., TANG Y.M., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationship of early premorbid adjustment with negative symptoms and cognitive functions in first-episode schizophrenia: a prospective three-year follow-up study, Psychiatry Research. 2013, 209 (3): 353-360.

Chang W.C., Chen S.M., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationships of suicidal ideation with symptoms, neurocognitive function, and psychological factors in patients with first-episode psychosis, Schizophrenia Research. 2014, 157 (1-3_: 12-18.

Chang W.C., Lau E.S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year outcome comparison between patients presenting with first-episode psychotic mania and schizophrenia to easy program in Hong Kong, Schizophrenia Research. 2014, 156 (S1): 304-305.

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013.

Hui C.L.M., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Comparing illness presentation, treatment and functioning between patients with early-and adult-onset psychosis, Schizophrenia Research. 2014, 153 (S1): 263-264.

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Hui C.L.M., TANG Y.M., Wong G.H.Y., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Predictors of help-seeking duration in adult-onset psychosis in Hong Kong, Social Psychiatry and Psychiatric Epidemiology. 2013, 48 (11): 1819-1828.

Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Li Y.K., Lee T.M. and Chen E.Y.H., Sexual dysfunction in Chinese patients with first-episode psychosis: prevalence, clinical correlates and functioning, Schizophrenia Research (Letter to the Editor). 2013, 148: 181-182.

LEE K.W., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Persistence of psychotic-like experiences (PLEs) in the general population of Hong Kong, Schizophrenia Research. 2014, 153 (S1): 137.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Comparison of characteristics of psychosis patients with and without hospitalization at first episode, Schizophrenia Research. 2014, 153 (S1): 168.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Ching Y.N.E. and Chen E.Y.H., Differential effects of antipsychotics on quality of life and functioning in Chinese patients with first-episode psychosis, Schizophrenia Research. 2014, 153 (S1): 282.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Li Y.K., LEE T.M., Lin J. and Chen E.Y.H., Impact of physical activity on functioning of patients with first-episode psychosis-A 6 months prospective longitudinal study, Schizophrenia Research. 2013, 150 (2): 538-541.

TANG Y.M., Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E., Yeung W.S., Wong C.K., Tang W.N., Chan W.F., Pang E.P.F., Tso S., Ng R.M.K., Hung S.F., Dunn E.L.W., Sham P.C. and Chen E.Y.H., Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study, Schizophrenia Research. 2014, 153 (1-3): 1-8.

Researcher : Hui TCK

List of Research Outputs

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : Koh YW

Project Title:	The Australasian Marce Society 2013 conference; A study of relationship between paternal mental health, maternal factors and impact on paternal fetal attachment: a longitudinal study.
Investigator(s):	Koh YW
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	10/2013
Completion Date:	10/2013

List of Research Outputs

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal Anxiety at the Second Trimester: Risk Factors and Effects on Anxiety and Infant Development at 6-Week Postpartum , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal anxiety in the first trimester: Risk factors and effects on anxiety and depression in the third trimester and 6-week postpartum, Open Journal of Psychiatry. 2013, 3: 301-310.

Koh Y.W., Chan C.Y., Lee A.M. and Tang C.S.K., A study of the relationship between paternal mental health, maternal factors and impact on paternal-fetal attachment: A longitudinal study, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden. Connecting Research to Clinical Practice. 2013.

Koh Y.W., Chan C.Y. and Lee A.M., The Impact of Gender Role and Traditionalism-modernity on Paternal Mental Health Problems among Hong Kong Expectant Fathers: A Longitudinal Study, Poster presentation at the 21st World Congress of Social Psychiatry, The University of Lisbon, Lisbon, Portugal (June 29-July 3, 2013). 2013.

Koh Y.W. and Lee A.M., The Prevalence of Paternal Depression in Antenatal and Postpartum period and the Relationships between Antenatal and Postpartum Depression among Fathers in Hong Kong, Depression Research and Treatment 2014. 2014.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Anxiety during Pregnancy: Prevalence and Its Relations to Postpartum Anxiety , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Depression across Pregnancy: Prevalence, Pattern and Relations to Postpartum Depression, Depression Research and Treatment 2014. 2014.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal anxiety across pregnancy: Prevalence, pattern and relations to postpartum anxiety, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden Connecting Research in Clinical Practice, Melbourne, Australia, October 21, 2013.

Researcher : Kwan SH

Project Title:	Statistical method for detecting disease associations with rare genetic variants, with application to analysis of osteoporosis genetic data
Investigator(s):	Kwan SH, Li M, Sham PC
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2014

Researcher : LEE KW

List of Research Outputs

LEE K.W., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Persistence of psychotic-like experiences (PLEs) in the general population of Hong Kong, Schizophrenia Research. 2014, 153 (S1): 137.

Researcher : LEE TM

List of Research Outputs

Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Li Y.K., Lee T.M. and Chen E.Y.H., Sexual dysfunction in Chinese patients with first-episode psychosis: prevalence, clinical correlates and functioning, Schizophrenia Research (Letter to the Editor). 2013, 148: 181-182.

LEE T.M., Lee H.M.E., Chan K.W. and Chang W.C., Understanding the physical activity behavior among patients with psychosis, Schizophrenia Research. 2014, 153 (S1): 137.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Li Y.K., LEE T.M., Lin J. and Chen E.Y.H., Impact of physical activity on functioning of patients with first-episode psychosis-A 6 months prospective longitudinal study, Schizophrenia Research. 2013, 150 (2): 538-541.

Researcher : LI Y

List of Research Outputs

LI Y., Samartzis D., Campbell D., Cheung K.M.C., Luk K.D.K., Karppinen J., Cheah K.S.E., Chan D. and Sham P.C., Best Short Talk Award, World Forum for Spine Research - Intervertebral Disc - from Degeneration to Therapeutic Motion Preservation, Xian, PR China, May 15-17, 2014. 2014.

LI Y., Samartzis D., Campbell D., Cheung K.M.C., Luk K.D.K., Karppinen J., Cheah K.S.E., Chan D. and Sham P.C., Comprehensive analysis of MRI-phenotypes provides new insights into lumbar disc degeneration for genetic studies, 41st Annual Meeting of International Society for the Study of the Lumbar Spine, Seoul, Korea, June 3-7, 2014.

Researcher : Lam M

List of Research Outputs

Lam L.C.W., Chan W.C., WONG S.M., Chen E.Y.H., Ng R.M.K., Lee H.M.E., Chang W.C., Hung S.F., CHeung E.F.C., Sham P.C., Chiu H.F.K., Lam M., Chiang T.P., J van O.S., Lau J.T.F., Lewis G., Bebbington P. and The Hong Kong Mental Morbidity Survey Team #., The Hong Kong Mental Morbidity Survey: background and Study Design, East Asian Archives of Psychiatry. 2014, 24 (1): 30-36.

Researcher : Lam MLM

List of Research Outputs

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Researcher : Lam SSY

Project Title:	Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Related Disorders
Investigator(s):	Lam SSY, McAlonan GM, Chua SE
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	12/2012
Completion Date:	02/2014

Project Title:	12th Human Proteome Organisation Congress; Altered Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Autism
Investigator(s):	Lam SSY
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	09/2013
Completion Date:	09/2013

List of Research Outputs

Lam S.S.Y., Wakuda T., Li Q., WEI R., ZHANG X., Chua S.E., Sham P.C., Takei N. and McAlonan G.M., Altered Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Autism, HUPO 2013.

Lam S.S.Y., liu Y., Ng K.M., Liong E.C., Tipoe G.L., Leung P.S. and Fung M.L., Upregulation of a local renin-angiotensin system in the rat carotid body during chronic intermittent hypoxia, Experimental Physiology. 2014, 99: 220-231.

Researcher : Lau WY

List of Research Outputs

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013, n/a-n/a.

Researcher : Law ACK

Project Title:	Linking the blood and the brain: The involvement of endothelial cell dysfunction in dementia pathogenesis.
Investigator(s):	Law ACK, Vanhoutte PMGR, Chang RCC
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2010

Project Title:	Intraneuronal transport defects and synaptic dysfunction: The common denominators for psychiatric disorders
Investigator(s):	Law ACK, McAlonan GM, Chang RCC
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2011

List of Research Outputs

Chang R.C.C., Wuwongse S., Wong S., Wong M.T.H., TSANG A.W.-.T., Zhang E., CHENG S.Y., Hung C.H.L., Lau W.M., Ho Y.S., So K.F. and Law A.C.K., Investigating biological mechanisms of corticosterone-induced neurodegeneration: Implication of how depression promotes cognitive impairment in Alzheimer's disease, Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2013, 9 Issue 4 Supplement: 561-562.

Chang R.C.C., Ho Y.S., WONG T.H.G., TSANG A.W.-.T., WUWONGSE S., POON C.H., YOU R., HUANG C., Ng T.W., CHENG S.Y., Hung C.H.L., LEUNG Y., Yang X., Law A.C.K., Chiu K., Lau W.M., Mak J.C.W., Wong G.T.C., Lee S.M.Y. and Hoi M.P.M., Investigating mechanisms of risk factors for Alzheimer’s disease to learn how to prevent disease progression., International Alzheimer’s Disease Conference 2014. 24.

Chang R.C.C., TSANG A.W.-.T., Wong G.T.H., CHENG S.Y., Hung C.H.L., Ho Y.S. and Law A.C.K., Targeting depression to prevent dementia and Alzheimer's disease, International Conference on Pharmacology and Drug Development, Singapore 2013.. 2013, : 65.

Chu L.W., Ng K.H.Y., Law A.C.K., Lee A.M. and Kwan F., Validity of the Cantonese Chinese Montreal Cognitive Assessment in Southern Chinese, Geriatrics & Gerontology International. 2014, n/a-n/a.

Jo W.K., Law A.C.K. and Chung S.K., The neglected co-star in the dementia drama: the putative roles of astrocytes in the pathogeneses of major neurocognitive disorders, Molecular Psychiatry. 2014, 19 (2): 159-167.

Leung A.Y.M., Chu D.W.S., Yung A., Wong J.G.W.S. and Law A.C.K., Depression care management programme in primary care setting: A pilot study, The Journal of Nutrition, Health & Aging. Springer Link, 2013, 17(1): S352.

WONG T.H.G., Hung C.H.L., TSANG A.W.-.T., Chang R.C.C. and Law A.C.K., Microtubule dysfunction in corticosterone and oligomeric beta-amyloid in vitro model and its effect on actin morphology., The 9th International Symposium of Healthy Aging. 2014, 50.

WUWONGSE S., CHENG S.Y., WONG T.H.G., Hung C.H.L., ZHANG Q., HO Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone and amyloid-beta on proteins essential for synaptic function: Implications for depression and Alzheimer's disease, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2013.

Wong G.T.H., Hung C.H.L., Law A.C.K. and Chang R.C.C., Oligomeric beta-amyloid and corticosterone trigger similar morphologic and dynamic changes in microtubules of cultured hippocampal neurons, Neuroscience 2013. Program # 40.11: Poster # G31.

Researcher : Law CW

List of Research Outputs

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Researcher : Lee AM

Project Title:	Psychosocial Group Therapy for Menopausal Women: A model for the non-pharmacological management of menopausal distress
Investigator(s):	Lee AM
Department:	Psychiatry
Source(s) of Funding:	Centre on Behavioral Health Seed Funding Scheme - General Award
Start Date:	07/2003

Project Title:	Prevalence and risk factors for paternal depression and anxiety in the antenatal period
Investigator(s):	Lee AM, Chung KF, Fong DYT, Law ACK, Leung KY
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	02/2009

List of Research Outputs

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal Anxiety at the Second Trimester: Risk Factors and Effects on Anxiety and Infant Development at 6-Week Postpartum , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Antenatal anxiety in the first trimester: Risk factors and effects on anxiety and depression in the third trimester and 6-week postpartum, Open Journal of Psychiatry. 2013, 3: 301-310.

Cheung Y.T.D., Wong P.W.C., Lee A.M., Lam T.H., Fan Y. and Yip P.S.F., Non-suicidal self-injury and suicidal behavior: prevalence, co-occurrence, and correlates of suicide among adolescents in Hong Kong, Social Psychiatry and Psychiatric Epidemiology. Springer-Verlag, 2013, 48(7): 1133-1144.

Chu L.W., Ng K.H.Y., Law A.C.K., Lee A.M. and Kwan F., Validity of the Cantonese Chinese Montreal Cognitive Assessment in Southern Chinese, Geriatrics & Gerontology International. 2014, n/a-n/a.

Koh Y.W., Chan C.Y., Lee A.M. and Tang C.S.K., A study of the relationship between paternal mental health, maternal factors and impact on paternal-fetal attachment: A longitudinal study, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden. Connecting Research to Clinical Practice. 2013.

Koh Y.W., Chan C.Y. and Lee A.M., The Impact of Gender Role and Traditionalism-modernity on Paternal Mental Health Problems among Hong Kong Expectant Fathers: A Longitudinal Study, Poster presentation at the 21st World Congress of Social Psychiatry, The University of Lisbon, Lisbon, Portugal (June 29-July 3, 2013). 2013.

Koh Y.W. and Lee A.M., The Prevalence of Paternal Depression in Antenatal and Postpartum period and the Relationships between Antenatal and Postpartum Depression among Fathers in Hong Kong, Depression Research and Treatment 2014. 2014.

Lee A.M., Anorexia Nervosa, AM730, March 24, 2014. 2014.

Lee A.M., Bulimia Nervosa, AM730, March 31, 2014. 2014.

Lee A.M., Expert Consultant & Panel Member, Primary Care Foundation 2013. 2013.

Lee A.M., Expert Consultant & Panel Member, Primary Care Foundation, Public Hospital and University Doctors' Association (PHUDA). 2014.

Lee A.M., Expert Consultant, Baby Magazine 2013-2014. 2013.

Lee A.M., Expert Consultant, Health Action Magazine 2013 and 2014. 2013.

Lee A.M., Founding Panel Consultant, E-Motion Alliance, Primary Care Foundation. 2014.

Lee A.M., Knowledge, Attitudes and Practices Working Group, Family Planning Association (2012-December 2013). 2013.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Anxiety during Pregnancy: Prevalence and Its Relations to Postpartum Anxiety , The Australasian Marcé Society 2013 Conference, Melbourne, Australia . 2013.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal Depression across Pregnancy: Prevalence, Pattern and Relations to Postpartum Depression, Depression Research and Treatment 2014. 2014.

Lee A.M., Chan C.Y., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Maternal anxiety across pregnancy: Prevalence, pattern and relations to postpartum anxiety, The Australian Marce Society 2013 Conference on Perinatal Mental Health: From Conception to Kindergarden Connecting Research in Clinical Practice, Melbourne, Australia, October 21, 2013.

Lee A.M., Research Subcommittee, Family Planning Association of HK (since March 2006-December 2014). 2014.

Lee A.M., Study of Psychology and Career Paths for Psychologists , SCMP Online 2013. 2013.

Lee A.M., Youth Sexuality Study Working Group, Family Planning Association (March 2013-December 2014). 2014.

Lee A.M., 齊來關心更年期女士, AM730. 2013.

Wong G.K.Y., To C.K.S., Lee A.M., Chan C.Y. and Lam G.Y.H., Effect of prenatal maternal depression on early speech sound acquisition, Paper presentation at 9th Asia Pacific Conference on Speech, Language and Hearing, Taiwan. 2013.

Wong K.Y.G., To K.S., Lee A.M., Lam Y.H. and Chan C.Y., Effect of prenatal maternal depression on early speech sound acquisition, Speech, Language, and Hearing.. 2013, Maney Publisher.

Yip P.S.F., Zhang H., Lam T.H., Lam K.F., Lee A.M., Chan J. and Fan S., Sex knowledge, attitudes, and high-risk sexual behaviors among unmarried youth in Hong Kong, In: William R Brieger, Till Bärnighausen, Mark R Cullen, William Cumberland, Jascha de Nooijer , BMC Public Health. BioMed Central, 2013, 13: 691.

Researcher : Lee HME

Project Title:	A Single-blinded Randomized Controlled Clinical Trial of Internet-assisted Aerobic Exercise (FitMind Program) in Patients with Early Psychosis
Investigator(s):	Lee HME, Chen EYH, Chan KW, Chang WC, Hui CLM, Wong GHY
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	09/2012

Project Title:	FitMind exercise for improving cognition: A train-the-trainer program for mental health caregivers in the community
Investigator(s):	Lee HME, Chen EYH, Chang WC, Chan KW, Hui CLM, Wong GHY, Tse MA
Department:	Psychiatry
Source(s) of Funding:	Health Care and Promotion Fund - Research Grant Projects
Start Date:	09/2013

Project Title:	WPA International Congress 2013; Promoting exercise habit in psychosis patients in the community: the Fitmind program in Hong Kong/Impact of physical inactivity on functioning of patients with first-episode psychosis - a 6 months prospective longitudinal study
Investigator(s):	Lee HME
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	10/2013
Completion Date:	10/2013

List of Research Outputs

Au R.W.C., Man D., Shum D., Lee H.M.E., Xiang Y.T., Ungvari G.S. and Tang W.K., Assessment of prospective memory in schizophrenia using the Chinese version of the Cambridge Prospective Memory Test: A controlled study, Asia Pacific Psychiatry. 2014, 6 (1): 54-61.

Au R.W.C., Ungvari G.S., Lee H.M.E., Man D., Shum D.H.K., Xiang Y.T. and Tang W.K., Prospective memory impairment and its implications for community living skills in bipolar disorder, Bipolar Disorders. 2013, 15 (8): 885-892.

CHAN C.W.T., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and predictors of disengagement from a 2-year early intervention program for psychosis in Hong Kong, Schizophrenia Research. 2014, 153 (1-3): 204-208.

CHAN C.W.T., Chang W.C., Gold J.M., Waltz J.A., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Reward learning impairment in patients with first-episode schizophrenia-spectrum disorder, Schizophrenia Research. 2014, 153 (S1): 220.

CHEN S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of suicidal behaviours in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow study, Schizophrenia Research. 2014, 153 (S1): 190.

Chan K.W., SO H.C., Hui C.L.M., Chang W.C., Lee H.M.E., Chung D.W.S., Tso S., Hung S.F., Yip K.C., Dunn E. and Chen E.Y.H., 10-year outcome study of an early intervention program for psychosis compared with standard care service, Psychological Medicine. 2014.

Chan K.W., CHAN K.S.K., Hui C.L.M., WONG H.Y.G., Chang W.C., Lee H.M.E., TANG Y.M. and Chen E.Y.H., Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective, Psychiatry Research. 2014, 216 (2): 177-184.

Chan K.W., Hui C.L.M., WONG H.Y.G., Lee H.M.E., Chang W.C. and Chen E.Y.H., Medication adherence, knowledge about psychosis, and insight among patients with a schizophrenia-spectrum disorder, Journal of Nervous and Mental Disease. 2014, 202 (1): 25-29.

Chang W.C., CHEN S.M., Chan K.W., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Evaluation of a community case-management program for patients with schizophrenia-spectrum disorder: a prospective 1-year case-control study, Schizophrenia Research. 2014, 153 (S1): 185-186.

Chang W.C., Hui C.L.M., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impacts of duration of untreated psychosis on cognition and negative symptoms in first-episode schizophrenia: a 3-year prospective follow-up study, Psychological Medicine. 2013, 43 (9): 1883-1893.

Chang W.C., Chang R., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and Predictors of depressive symptoms in non-affective psychosis patients in Jockey Club Early Psychosis (JCEP) Project in Hong Kong, Schizophrenia Research. 2014, 153 (S1): 267.

Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E., WONG H.Y.G. and Chen E.Y.H., Relationship between diminished expression and cognitive impairment in first-episode schizophrenia: A prospective three-year follow-up study, Schizophrenia Research. 2014, 152 (1): 146-151.

Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Symptomatic remission and cognitive impairment in first-episode schizophrenia: a prospective 3-year follow-up study, Journal of Clinical Psychiatry. 2013, 74 (11): e1046-1053.

Chang W.C., TANG Y.M., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationship of early premorbid adjustment with negative symptoms and cognitive functions in first-episode schizophrenia: a prospective three-year follow-up study, Psychiatry Research. 2013, 209 (3): 353-360.

Chang W.C., Chen S.M., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationships of suicidal ideation with symptoms, neurocognitive function, and psychological factors in patients with first-episode psychosis, Schizophrenia Research. 2014, 157 (1-3_: 12-18.

Chang W.C., Lau E.S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year outcome comparison between patients presenting with first-episode psychotic mania and schizophrenia to easy program in Hong Kong, Schizophrenia Research. 2014, 156 (S1): 304-305.

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013, n/a-n/a.

Hui C.L.M., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Comparing illness presentation, treatment and functioning between patients with early-and adult-onset psychosis, Schizophrenia Research. 2014, 153 (S1): 263-264.

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Hui C.L.M., TANG Y.M., Wong G.H.Y., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Predictors of help-seeking duration in adult-onset psychosis in Hong Kong, Social Psychiatry and Psychiatric Epidemiology. 2013, 48 (11): 1819-1828.

Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Li Y.K., Lee T.M. and Chen E.Y.H., Sexual dysfunction in Chinese patients with first-episode psychosis: prevalence, clinical correlates and functioning, Schizophrenia Research (Letter to the Editor). 2013, 148: 181-182.

LEE K.W., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., Persistence of psychotic-like experiences (PLEs) in the general population of Hong Kong, Schizophrenia Research. 2014, 153 (S1): 137.

LEE T.M., Lee H.M.E., Chan K.W. and Chang W.C., Understanding the physical activity behavior among patients with psychosis, Schizophrenia Research. 2014, 153 (S1): 137.

Lam L.C.W., Chan W.C., WONG S.M., Chen E.Y.H., Ng R.M.K., Lee H.M.E., Chang W.C., Hung S.F., CHeung E.F.C., Sham P.C., Chiu H.F.K., Lam M., Chiang T.P., J van O.S., Lau J.T.F., Lewis G., Bebbington P. and The Hong Kong Mental Morbidity Survey Team #., The Hong Kong Mental Morbidity Survey: background and Study Design, East Asian Archives of Psychiatry. 2014, 24 (1): 30-36.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Comparison of characteristics of psychosis patients with and without hospitalization at first episode, Schizophrenia Research. 2014, 153 (S1): 168.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Ching Y.N.E. and Chen E.Y.H., Differential effects of antipsychotics on quality of life and functioning in Chinese patients with first-episode psychosis, Schizophrenia Research. 2014, 153 (S1): 282.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Li Y.K., LEE T.M., Lin J. and Chen E.Y.H., Impact of physical activity on functioning of patients with first-episode psychosis-A 6 months prospective longitudinal study, Schizophrenia Research. 2013, 150 (2): 538-541.

Leung M.C., Stone W.S., Lee H.M.E., Seidman L.J. and Chen E.Y.H., Impaired facilitation of self-control cognition by glucose in patients with schizophrenia: A randomized controlled study, Schizophrenia Research. 2014, 156 (1): 38-45.

Lin J., Lee H.M.E. and Chen E.Y.H., HKU study reveals yoga improves neurocognitive functions in early psychosis, Press release of HKU, 2014.

Lin J., Lee H.M.E., Chan K.W., Chang W.C., Su W., Honer W.G., Khong P.L., Tse M.A., Chan C.L.W., So K.F. and Chen E.Y.H., The impacts of aerobic exercise and mind-body exercise (yoga) on neuro-cognition and clinical symptoms in early psychosis: a single-blind randomized controlled clinical trial , Schizophrenia Research. 2014, 153 (S1): 260.

TANG Y.M., Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E., Yeung W.S., Wong C.K., Tang W.N., Chan W.F., Pang E.P.F., Tso S., Ng R.M.K., Hung S.F., Dunn E.L.W., Sham P.C. and Chen E.Y.H., Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study, Schizophrenia Research. 2014, 153 (1-3): 1-8.

Xiang Y.T., Li Y., Correll C.U., Ungvari G.S., Chiu H.F.K., Lai K.Y.C., Tang Q.S., Hao W., Si T.M., Wang C.Y., Lee H.M.E., He Y.L., Yang S.Y., Chong M.Y., Kua E.H., Fujii S., Sim K., Yong M.K.H., Trivedi J.K., Chung E.K., Udomratn P., Chee K.Y., Sartorius N., Tan C.H. and Shinfuku N., Common use of high doses of antipsychotic medications in older Asian patients with schizophrenia (2001-2009), International Journal of Geriatric Psychiatry. 2014, 29 (4): 359-366.

Zhou J.J., Xiang Y.T., Wang C.Y., Zhou F.C., Ungvari G.S., Dickerson F., Chiu H.F., Lai K.Y., Shum D.H., Lee H.M.E., Au R.W., Tang W.K. and Man D., Prospective memory deficits in euthymic bipolar disorder patients: a preliminary study, Asia Pacific Psychiatry. 2013, 5 (3): 183-190.

Researcher : Lee PWH

Project Title:	A study of risk factors for exposure to AIDS in high risk adolescent Chinese females
Investigator(s):	Lee PWH
Department:	Psychiatry
Source(s) of Funding:	Council for the AIDS Trust Fund - General Award
Start Date:	04/1997

Project Title:	Psychological adjustment and stresses of nurses working in acute hospital
Investigator(s):	Lee PWH
Department:	Psychiatry
Source(s) of Funding:	Other Funding Scheme
Start Date:	06/1997

Project Title:	The psychosocial outcomes and well-being of living related donors involved in liver transplantation surgery: a follow-up study of risk factors, resilience, and outcome predictors
Investigator(s):	Lee PWH, Fan ST, Fung ASM
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	11/2003

List of Research Outputs

Chin W.Y., Lam C.L.K., Wong S.Y.S., Lo Y.C.Y., Fong D.Y.T., Lam T.P., Lee P.W.H., Wong J.G.W.S. and Chan T.Y., Findings of a longitudinal cohort study on depressive disorders in Hong Kong’s primary care, WONCA Asia Pacific 2014.

Researcher : Lee TM

List of Research Outputs

LEE T.M., Lee H.M.E., Chan K.W. and Chang W.C., Understanding the physical activity behavior among patients with psychosis, Schizophrenia Research. 2014, 153 (S1): 137.

Researcher : Leung MC

List of Research Outputs

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013.

Leung M.C., Stone W.S., Lee H.M.E., Seidman L.J. and Chen E.Y.H., Impaired facilitation of self-control cognition by glucose in patients with schizophrenia: A randomized controlled study, Schizophrenia Research. 2014, 156 (1): 38-45.

Researcher : Li M

Project Title:	Mine host genetic factors affecting progression of chronic Hepatitis B virus infection in an exome sequencing data set
Investigator(s):	Li M, Sham PC
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2013

Project Title:	Statistical method to identify risk genes of complex diseases based on functional gene sets and networks, with a genetic data mining application to hepatocellular carcinoma
Investigator(s):	Li M, Sham PC, Ng IOL, Kwan SH
Department:	Psychiatry
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	05/2014

Project Title:	A method and tool to combine statistics and functional evidences for characterizing cancer-driver genes and pathways in exome sequencing study
Investigator(s):	Li M, Kwan SH, Ng IOL, Sham PC
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	06/2014

List of Research Outputs

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Zhou K.X., Donnelly L., Yang J., Li M., Deshmukh H., Zuydam N.V., Ahlqvist E., Spencer C.C., Groop L., Morris A.D., Colhoun H.M., Sham P.C., McCarthy M.L., Palmer C.N.A. and Pearson E.R., Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis, The Lancet Diabetes & Endocrinology. 2014, 2 (6): 481-487.

Researcher : Li Q

Project Title:	Effects of DNA methylation of reelin and glutamic acid decarboxylase 67 (GAD67) on cognitive function in mice exposed to immune challenge in early or late pregnancy
Investigator(s):	Li Q, McAlonan GM, Chua SE
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2012
Completion Date:	05/2014

Project Title:	Serotonin transporter (Sert) gene silence in the frontal cortex by in utero electroporation: a promising platform for generating a novel mouse model for neurodevelopmental psychiatric disorders
Investigator(s):	Li Q, Chen EYH, Cheung MCH, Lee HME, Chan SY
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	01/2014

List of Research Outputs

BASIL P., Li Q., Dempster E.L., Wong P.C., Sham P.C., Mill J. and McAlonan G.M., Dietary intervention on the epigenetic changes induced by environmental risk factors in the adolescent brain, HGM. 2014.

CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., Enriched housing condition reduces stressful behavior in Lrrc7 mutant mice, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong, 12-14 June 2014.

FUNG C.M.G., Cheung C., Chen E.Y.H., Lam C.A.R.M.E.N., Chiu C.I.N.D.Y., Law C.H.I.-.W.I.N.G., Leung M.K., Deng M.I.C.H.E.L.L.E., Cheung V.I.N.C.I., Li Q., YAO N., Tai K.S., Yip L.A.W.R.A.N.C.E., Suckling J.O.H.N., Sham P.C., McAlonan G.M. and Chua S.E., MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes, Neuropsychobiology. 2014, 69 (4): 243-248.

Lam S.S.Y., Wakuda T., Li Q., WEI R., ZHANG X., Chua S.E., Sham P.C., Takei N. and McAlonan G.M., Altered Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Autism, HUPO 2013.

Li Q., Chan W.M., Rudd J.A., Wang C.M., Lam P.H.O.E.B.E., Wai M.A.R.I.A., Wood D.A.V.I.D., Dargan P.A.U.L. and Yew D.A.V.I.D., Ketamine, In: Paul Dargan & David Wood, Novel Psychoactive Substances, 1st Edition. Elsevier, 2013.

NG C.P., Li Q. and Chan S.Y., The Role of Densin180 in Anxiety Behavior and Protein Distribution, 18^th Research Postgraduate Symposium, the University of Hong Kong (Hong Kong), 11-12 December 2013.

TSANG K.H., Lai S.K., Li Q., Yung W.H., LIU H., Mak H.S., NG C.P., McAlonan G.M., Chan Y.S. and Chan S.Y., The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B, Scientific Reports. 2014, 4: 3654.

Zhou J.I.A.N.S.O.N.G., Cao X.I.A., Mar A.D.A.M. .C., Ding Y.U.Q.I.A.N.G., Wang X.I.A.O.P.I.N.G., Li Q. and Li L.I.N.G.J.I.A.N.G., Activation of post-synaptic 5-HT1A receptors improve stress adaptation, Psychopharmacology. 2014, 231 (10): 2067-75.

Researcher : Li YK

List of Research Outputs

Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Li Y.K., Lee T.M. and Chen E.Y.H., Sexual dysfunction in Chinese patients with first-episode psychosis: prevalence, clinical correlates and functioning, Schizophrenia Research (Letter to the Editor). 2013, 148: 181-182.

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Li Y.K., LEE T.M., Lin J. and Chen E.Y.H., Impact of physical activity on functioning of patients with first-episode psychosis-A 6 months prospective longitudinal study, Schizophrenia Research. 2013, 150 (2): 538-541.

Researcher : Lin J

List of Research Outputs

Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Li Y.K., LEE T.M., Lin J. and Chen E.Y.H., Impact of physical activity on functioning of patients with first-episode psychosis-A 6 months prospective longitudinal study, Schizophrenia Research. 2013, 150 (2): 538-541.

Lin J., Lee H.M.E. and Chen E.Y.H., HKU study reveals yoga improves neurocognitive functions in early psychosis, Press release of HKU, 2014.

Lin J., The Impacts of Aerobic Exercise and Mind-body Exercise (Yoga) on Neuro-Cognition and Clinical Symptoms in Early Psychosis-A Single-Blind Randomized Controlled Clinical Trial , The University of Hong Kong. 2013.

Lin J., Lee H.M.E., Chan K.W., Chang W.C., Su W., Honer W.G., Khong P.L., Tse M.A., Chan C.L.W., So K.F. and Chen E.Y.H., The impacts of aerobic exercise and mind-body exercise (yoga) on neuro-cognition and clinical symptoms in early psychosis: a single-blind randomized controlled clinical trial , Schizophrenia Research. 2014, 153 (S1): 260.

Researcher : Mak KY

Project Title:	Program enhancement for the mental-ill patients at the S.K. Yee Mental Health Resource and Rehabilitation Centre
Investigator(s):	Mak KY, Wong MMC, Mak-Lieh F, Yau EFY
Department:	Psychiatry
Source(s) of Funding:	S.K. Yee Medical Foundation - General Award
Start Date:	09/2000

Researcher : McAlonan GM

Project Title:	King's/HKU Fellowship Awards 2008-09
Investigator(s):	McAlonan GM
Department:	Psychiatry
Source(s) of Funding:	King's/HKU Fellowship Awards
Start Date:	09/2008

Project Title:	Preventing schizophrenia-like phenotype in the mouse model
Investigator(s):	McAlonan GM, Chua SE, Lam SSY, Wang Y, Li Q
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	03/2010

Project Title:	MRI aided diagnosis of autism
Investigator(s):	McAlonan GM, Cheung C, Chua SE
Department:	Psychiatry
Source(s) of Funding:	Seed Funding Programme for Basic Research
Start Date:	01/2011

List of Research Outputs

BASIL P., Li Q., Dempster E.L., Wong P.C., Sham P.C., Mill J. and McAlonan G.M., Dietary intervention on the epigenetic changes induced by environmental risk factors in the adolescent brain, HGM. 2014.

CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., Enriched housing condition reduces stressful behavior in Lrrc7 mutant mice, Physiology Symposium 2014 & Joint Scientific Conference of The Hong Kong Society of Neurosciences & The Biophysical Society of Hong Kong, 12-14 June 2014.

FUNG C.M.G., Cheung C., Chen E.Y.H., Lam C.A.R.M.E.N., Chiu C.I.N.D.Y., Law C.H.I.-.W.I.N.G., Leung M.K., Deng M.I.C.H.E.L.L.E., Cheung V.I.N.C.I., Li Q., YAO N., Tai K.S., Yip L.A.W.R.A.N.C.E., Suckling J.O.H.N., Sham P.C., McAlonan G.M. and Chua S.E., MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes, Neuropsychobiology. 2014, 69 (4): 243-248.

Lam S.S.Y., Wakuda T., Li Q., WEI R., ZHANG X., Chua S.E., Sham P.C., Takei N. and McAlonan G.M., Altered Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Autism, HUPO 2013.

TSANG K.H., Lai S.K., Li Q., Yung W.H., LIU H., Mak H.S., NG C.P., McAlonan G.M., Chan Y.S. and Chan S.Y., The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B, Scientific Reports. 2014, 4: 3654.

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : NG HY

List of Research Outputs

Chung K.F., Yu Y.M.B., YUNG K.P., Yeung W.F., NG H.Y. and HO Y.Y.F., Assessment of fatigue using the Multidimensional Fatigue Inventory in patients with major depressive disorder, Comprehensive Psychiatry. 2014.

Yeung W.F., Chung K.F., YUNG K.P. and NG H.Y., Doxepin for Insomnia: A Systematic Review of Randomized Placebo-controlled Trials, Sleep Medicine Reviews. 2014.

Researcher : Ng KY

List of Research Outputs

Yeung W.F., Chung K.F., Ng K.Y., Yu Y.M.B., Ziea E.T.C. and Ng B.F.L., A Systematic Review on the Efficacy, Safety and Types of Chinese Herbal Medicine for Depression, Journal of Psychiatric Research. 2014.

Yeung W.F., Chung K.F., Ng K.Y., Yu Y.M.B., Ziea E.T.C. and Ng B.F.L., A meta-analysis of the efficacy and safety of traditional Chinese medicine formula Ganmai Dazao decoction for depression, Journal of Ethnopharmacology. 2014, 153 (2): 309-317.

Researcher : Ng ML

Project Title:	Violence on male genitalia - a ten year review of cases in Hong Kong
Investigator(s):	Ng ML
Department:	Psychiatry
Source(s) of Funding:	Other Funding Scheme
Start Date:	05/2002

Researcher : PORSCH RM

List of Research Outputs

PORSCH R.M., Merello E., De Marco P., So M.T., Sham P.C., Tam P.K.H., Cherny S.S., Capra V., Garcia-Barcelo M.M. and Campbell D.D., De novo mutations associated with sporadic cases of caudal regression syndrome, European Conference of Human Genetics, Milan, Italy, 31 May - 3 June 2014.

Researcher : SO HC

List of Research Outputs

Chan K.W., SO H.C., Hui C.L.M., Chang W.C., Lee H.M.E., Chung D.W.S., Tso S., Hung S.F., Yip K.C., Dunn E. and Chen E.Y.H., 10-year outcome study of an early intervention program for psychosis compared with standard care service, Psychological Medicine. 2014.

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : Sham PC

Project Title:	Replication study of susceptibility genes for colorectal cancer
Investigator(s):	Sham PC, Ho JWC, Cheng KK
Department:	LKS Medical Faculty
Source(s) of Funding:	Small Project Funding
Start Date:	10/2007

Project Title:	The State Key Laboratory of Brain and Cognitive Sciences
Investigator(s):	Sham PC, So KF, Tan L
Department:	Centre for Genomic Sciences
Source(s) of Funding:	Matching Fund for State Key Laboratory (SKL)
Start Date:	10/2008

Project Title:	Visiting Research Professors Scheme 2009-10
Investigator(s):	Sham PC
Department:	LKS Medical Faculty
Source(s) of Funding:	Visiting Research Professors Scheme
Start Date:	09/2009

Project Title:	To determine the functional variants of candidate genes identified by Genome-wide Association Study of Osteoporosis
Investigator(s):	Sham PC, Gao RY, Xiao S, Kung AWC
Department:	LKS Medical Faculty
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	07/2010

Project Title:	Predicting and preventing schizophrenia in the mouse model.
Investigator(s):	Sham PC, Wu EX, McAlonan GM, Cheung C, Chua SE
Department:	LKS Medical Faculty
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	12/2010

Project Title:	Method and Software for Personal Risk Profiling of Complex Diseases
Investigator(s):	Sham PC, Cherny SS, Garcia-Barcelo MM, Kung AWC, Li M, Yang W
Department:	Psychiatry
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2012

Project Title:	Bioinformatics tools for identifying disease loci from exome sequencing data
Investigator(s):	Sham PC, Cherny SS, Garcia-Barcelo MM, Li M, Yang W
Department:	Psychiatry
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2013

Project Title:	Genomics
Investigator(s):	Sham PC, Chin FYL, Leung FCC
Department:	LKS Medical Faculty
Source(s) of Funding:	Seed Funding for Strategic Research Theme
Start Date:	06/2013

Project Title:	Statistical methods for characterizing the genetic component of polygenic diseases
Investigator(s):	Sham PC, Cherny SS
Department:	Psychiatry
Source(s) of Funding:	General Research Fund (GRF)
Start Date:	01/2014

Project Title:	Mutational spectrum for dilated cardiomyopathy in Hong Kong
Investigator(s):	Sham PC, Tse HF, Cherny SS, Garcia-Barcelo MM, Tang SM, Li M
Department:	Centre for Genomic Sciences
Source(s) of Funding:	Health and Medical Research Fund - Full Grant
Start Date:	04/2014

List of Research Outputs

CHENG G., Tang S.M., Wong H.M.E., Cheng W.C., So M.T., Miao X., ZHANG R., CUI L., Liu X., Ngan E.S.W., Lui V.C.H., Chung H.Y., Chan I.H.Y., Liu J.C., Zhong W., Xia H.M., Yu J.K., Qiu X., Wu X.Z., Wang B., Dong X., Tou J.F., Huang L.M., Yi B., Ren H.X., Chan E.K.W., Ye K., O'Reilly P.F., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Common genetic variants regulating ADD3 gene expression alter biliary atresia risk, Journal of Hepatology. 2013, 59(6): 1285-1291.

Cherny S.S., GUI H., Jiang C.Q., Sham P.C., Xu L., Liu B., Jin Y.L., Zhu T., Zhang W.S., Thomas G.N., Cheng K.K. and Lam T.H., Influence of Alzheimer's disease genes on cognitive decline: the Guangzhou Biobank Cohort Study, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 1190W, Boston, Massachusetts, October 23, 2013.

Cheung J.P.Y., Samartzis D., Kao P.Y.P., Shigematsu H.I.D.E.K.I., Cheah K.S.E., Song Y., Sham P.C., Chan D. and Cheung K.M.C., AR Hodgson Award - Prediction of Lumbar Spinal Stenosis in Chinese: Findings from a Genome-wide Association Study, 33rd Annual Congress of The Hong Kong Orthopaedic Association. 2013.

Cheung J.P.Y., Samartzis D., Kao P.Y.P., Shigematsu H.I.D.E.K.I., Cheah K.S.E., Song Y., Sham P.C., Chan D. and Cheung K.M.C., Prediction of Lumbar Spinal Stenosis in Chinese: Findings from a Genome-wide Association Study (Awards session AR Hodgson Winner), 33rd Hong Kong Orthopaedic Association Annual Congress. 2013.

Cheung J.P.Y., Samartzis D., Kao P.Y.P., Shigematsu H., Cheah K.S.E., Song Y., Sham P.C., Chan D. and Cheung K.M.C., Prediction of Lumbar Spinal Stenosis in Chinese: Findings from a Genome-wide Association StudyGenome-wide association study of Spinal Stenosis in Southern Chinese: The first of its kind, 33rd Hong Kong Orthopaedic Association Annual Congress. Hong Kong, 2013.

Cheung Y.Y., Hui Y.L.E., Cheung B.M.Y., Tso A.W.K., Xu A., Fong H.Y., Ong K.L., Wat N.M.S., Janus E.D., Tse H.F., Sham P.C. and Lam K.S.L., Adiponectin gene variant +276G>T independently predicts incident coronary heart disease in men: a 16-year prospective study, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.

Chiang K.M., Yang H.C., Liang Y.J., Chen J.W., Hwang S.M., Ho H.Y., Ting C.T., Lin T.H., Sheu S.H., Tsai W.C., Chen J.H., Leu H.B., Yin W.H., Chiu T.Y., Chen C.I., Lin S.J., Thomas G.N., Tomlinson B., Guo Y.L., Gui H.S., Sham P.C., Lam T.H. and Pan W.H., A three-stage genome-wide association study combining multilocus test and gene expression analysis for young-onset hypertension in Taiwan Han Chinese, American Journal of Hypertension. 2014, 27(6): 819-27.

FUNG C.M.G., Cheung C., Chen E.Y.H., Lam C.A.R.M.E.N., Chiu C.I.N.D.Y., Law C.H.I.-.W.I.N.G., Leung M.K., Deng M.I.C.H.E.L.L.E., Cheung V.I.N.C.I., Li Q., YAO N., Tai K.S., Yip L.A.W.R.A.N.C.E., Suckling J.O.H.N., Sham P.C., McAlonan G.M. and Chua S.E., MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes, Neuropsychobiology. 2014, 69 (4): 243-248.

LI J., Wang Y., Xia Z.Y., Sham P.C. and Wang J.J., GWAS3D: Detecting Human Regulatory Variants by Integrative Analysis of Genome-wide Associations and Chromosome States , 18th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, December 11 & 12, 2013.

LI J., WANG Y., Xia Z., Sham P.C. and Wang J.J., GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications, Nucleic Acids Res. 2013, 41(W1): W150-W158.

LI J., WANG Y., Xia Z., Wong M.P., Sham P.C. and Wang J.J., The best poster presentation award, The 5th International Conference on Computational and Systems Biology, SUSTC, Shenzhen, Nov15, 2013 . 2013.

LI J., WANG Y., Xia Z., Wong M.P., Sham P.C. and Wang J.J., dbPSHP: a database of recent positive selection across human populations, Nucleic Acids Res. 2013.

LI J., WANG Y., Xia Z., Wong M.P., Sham P.C. and Wang J.J., dbPSHP: a database of recent positive selection across human populations, Nucleic Acids Res. 2014, 42(Database issue): D910-6.

LI Y., Samartzis D., Campbell D., Cheung K.M.C., Luk K.D.K., Karppinen J., Cheah K.S.E., Chan D. and Sham P.C., Best Short Talk Award, World Forum for Spine Research - Intervertebral Disc - from Degeneration to Therapeutic Motion Preservation, Xian, PR China, May 15-17, 2014. 2014.

LI Y., Samartzis D., Campbell D., Cheung K.M.C., Luk K.D.K., Karppinen J., Cheah K.S.E., Chan D. and Sham P.C., Comprehensive analysis of MRI-phenotypes provides new insights into lumbar disc degeneration for genetic studies, 41st Annual Meeting of International Society for the Study of the Lumbar Spine, Seoul, Korea, June 3-7, 2014.

Lam L.C.W., Chan W.C., WONG S.M., Chen E.Y.H., Ng R.M.K., Lee H.M.E., Chang W.C., Hung S.F., CHeung E.F.C., Sham P.C., Chiu H.F.K., Lam M., Chiang T.P., J van O.S., Lau J.T.F., Lewis G., Bebbington P. and The Hong Kong Mental Morbidity Survey Team #., The Hong Kong Mental Morbidity Survey: background and Study Design, East Asian Archives of Psychiatry. 2014, 24 (1): 30-36.

Lam S.S.Y., Wakuda T., Li Q., WEI R., ZHANG X., Chua S.E., Sham P.C., Takei N. and McAlonan G.M., Altered Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Autism, HUPO 2013.

Li Y., Samartzis D., Campbell D., Cheung K.M.C., Luk K.D.K., Karppinen J.I., Cheah K.S.E., Chan D. and Sham P.C., Comprehensive Analysis of MRI-Phenotypes Provides New Insights into Lumbar Disc Degeneration for Genetic Studies, World Forum for Spine Research - Intervertebral Disc—from Degeneration to Therapeutic Motion Preservation. Xi'An, China, 2014.

Li Y., Samartzis D., Campbell D., Cheung K.M.C., Luk K.D.K., Karppinen J.I., Cheah K.S.E., Chan D. and Sham P.C., Comprehensive analaysis of MRI-phenotypes provides new insights into lumbar disc degeneration for genetic studies, 43rd Annual Meeting of the International Society for the Study of the Lumbar Spine. Seoul, Korea, 2014.

Londono D., Kou I., Johnson T.A., Sharma S., Ogura Y., Tsunoda T., Takahashi A., Matsumoto M., Herring J.A., Lam T.P., Wang X., Tam E.M., Song Y., Fan Y., Chan D., Cheah K.S.E., Qiu X., Jiang H., Huang D., Japanese Scoliosis Clinical Research Group ,., TSRHC IS Clinical Group ,., the International Consortium for Scoliosis Genetics ,., Su P., Sham P.C., Cheung K.M.C., Luk K.D.K., Gordon D., Qiu Y. and Cheng J., Tang N., Ikegawa S., Wise C.A., A meta-analysis identifies adolescent idiopathic scoliosis association with LBX1 locus in multiple ethnic groups. , J Med Genet. . 2014, 51: 401-406.

PORSCH R.M., Merello E., De Marco P., So M.T., Sham P.C., Tam P.K.H., Cherny S.S., Capra V., Garcia-Barcelo M.M. and Campbell D.D., De novo mutations associated with sporadic cases of caudal regression syndrome, European Conference of Human Genetics, Milan, Italy, 31 May - 3 June 2014.

Song Y., Karasugi T., Cheung K.M.C., Chiba K., Ho D.W.H., Miyake A., Kao P.Y.P., Sze K.L., Yee F.Y.A., Takahashi A., Kawaguchi Y., Mikami Y., Matsumoto M., Togawa D., Kanayama M., Shi D., Dai J., Jiang Q., Wu C., Tian W., Wang N., Leong J.C.Y., Luk K.D.K., Yip S.P., Cherny S.S., Wang J.J., Mundlos S., Kelempisioti A., Eskola P.J., Mannikko M., Makela P., Karppinen J., Jarvelin M.R., O'Reilly P.F., Kubo M., Kimura T., Kubo T., Toyoma Y., Mizuta H., Cheah K.S.E., Tsunoda T., Sham P.C., Ikegawa S. and Chan D., Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant., J. Clin. Invest . 2013, 123: 4909-4917.

TANG Y.M., Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E., Yeung W.S., Wong C.K., Tang W.N., Chan W.F., Pang E.P.F., Tso S., Ng R.M.K., Hung S.F., Dunn E.L.W., Sham P.C. and Chen E.Y.H., Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study, Schizophrenia Research. 2014, 153 (1-3): 1-8.

Tang S.M., WONG H.M.E., GUI H., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Comprehensive comparison of copy number variations detection using Illumina Omni 2.5M and Affymetrix CytoScan arrays, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 552T, Boston, Massachusetts, October 24, 2013.

WANG W., XU F., WANG P., LI J., Sham P.C. and Wang J.J., Assessment of Aligner and SNP Caller for Next Generation Sequencing and a Fast and Accurate SNP Detection Method., The 21st Annual International Conference on Intelligent Systems for Molecular Biology (ISMB 2013) and the 12th Annual European Conference on Computational Biology (ECCB), Berlin, Germany,19-23 July, 2013.

WONG H.M.E., NG C.L., Lui V.C.H., So M.T., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Gene network analysis of candidate loci for human anorectal malformations. , PLoS One . 2013, 8(8): e69142.

WONG H.M.E., Ng C.L., Lui V.C.H., So M.T., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Gene network analysis of candidate loci for human anorectal malformations, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 1027T. Boston, Massachusetts, October 24, 2013.

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

ZHANG J., ZHANG Y., Yang J., Zhang L., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians, Human Molecular Genetics. 2014, 23(2): 524-533.

Zeng H., Lee T.M.C., Walters J.H., So K.F., Sham P.C., Schottenfeld R.S., Marienfeld C. and Chawarski M.C., Impulsivity, cognitive function, and their relationship in heroin-dependent individuals, Journal of Clinical and Experimental Neuropsychology. 2013, 35(9): 897-905.

Zhang X.W., Sham P.C., Cherny S.S., Meng H.Q., Fu Y.X., Huang Y. and Li T., Parents and teachers report on different aspect[s] of children's and adolescent's conduct disorder and hyperactivity/inattention behavior, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 1255F, Boston, Massachusetts, October 25, 2013.

Zhou K.X., Donnelly L., Yang J., Li M., Deshmukh H., Zuydam N.V., Ahlqvist E., Spencer C.C., Groop L., Morris A.D., Colhoun H.M., Sham P.C., McCarthy M.L., Palmer C.N.A. and Pearson E.R., Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis, The Lancet Diabetes & Endocrinology. 2014, 2 (6): 481-487.

Researcher : TANG YM

List of Research Outputs

Chan K.W., CHAN K.S.K., Hui C.L.M., WONG H.Y.G., Chang W.C., Lee H.M.E., TANG Y.M. and Chen E.Y.H., Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective, Psychiatry Research. 2014, 216 (2): 177-184.

Chang W.C., Hui C.L.M., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impacts of duration of untreated psychosis on cognition and negative symptoms in first-episode schizophrenia: a 3-year prospective follow-up study, Psychological Medicine. 2013, 43 (9): 1883-1893.

Chang W.C., TANG Y.M., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationship of early premorbid adjustment with negative symptoms and cognitive functions in first-episode schizophrenia: a prospective three-year follow-up study, Psychiatry Research. 2013, 209 (3): 353-360.

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013.

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Hui C.L.M., TANG Y.M., Wong G.H.Y., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Predictors of help-seeking duration in adult-onset psychosis in Hong Kong, Social Psychiatry and Psychiatric Epidemiology. 2013, 48 (11): 1819-1828.

TANG Y.M., Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E., Yeung W.S., Wong C.K., Tang W.N., Chan W.F., Pang E.P.F., Tso S., Ng R.M.K., Hung S.F., Dunn E.L.W., Sham P.C. and Chen E.Y.H., Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study, Schizophrenia Research. 2014, 153 (1-3): 1-8.

Researcher : Tam WWY

List of Research Outputs

Tam W.W.Y. and Chen E.Y.H., Cognitive Behavioral Case Management (CBCM) for Early Psychosis: A Hong Kong Experience, Advances in Psychology Research. 2013, 97: 117-131.

Researcher : Tang SM

Project Title:	American Society of Human Genetics 2013; Comprehensive comparison of copy number variations detection using Illumina Omni 2.5M and Affymetrix CytoScan arrays
Investigator(s):	Tang SM
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	10/2013
Completion Date:	10/2013

Project Title:	A transethnic meta-analysis of genome-wide association studies for Hirschsprung disease
Investigator(s):	Tang SM, Tam PKH, Sham PC, Garcia-Barcelo MM, Cherny SS
Department:	Psychiatry
Source(s) of Funding:	Health and Medical Research Fund - Mini Grant
Start Date:	01/2014

Project Title:	Copy number variation in syndromic Hirschsprung disease patients
Investigator(s):	Tang SM, Garcia-Barcelo MM, Cherny SS, Sham PC, Tam PKH
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2014

List of Research Outputs

CHENG G., Tang S.M., Wong H.M.E., Cheng W.C., So M.T., Miao X., ZHANG R., CUI L., Liu X., Ngan E.S.W., Lui V.C.H., Chung H.Y., Chan I.H.Y., Liu J.C., Zhong W., Xia H.M., Yu J.K., Qiu X., Wu X.Z., Wang B., Dong X., Tou J.F., Huang L.M., Yi B., Ren H.X., Chan E.K.W., Ye K., O'Reilly P.F., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Common genetic variants regulating ADD3 gene expression alter biliary atresia risk, Journal of Hepatology. 2013, 59(6): 1285-1291.

Ferreira M.A.R., Matheson M.C., Tang S.M., Granell R., Ang W., Hui J., Kiefer A.K., Duffy D.L., Baltic S. and Danoy P., Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype, Journal of Allergy and Clinical Immunology. 2014, 133: 1564-1571.

Hofstra R.M.W., Gui H., Schriemer D., Griseri P., Pelet A., Ruiz-Ferrer M., Berrios C., van Ijcken W., van den Hout M., Tam P.K.H., Cheng W., Tang S.M., Eggen B.J.L., Matera I., Ceccherini I., Amiel J., Lyonnet S., Antinolo G., Borrego S., Chakravarti A. and Garcia-Barcelo M.M., Exonic de novo mutations in sporadic Hirschsprung disease, European Conference of Human Genetics, Milan, Italy, 31 May - 3 June 2014.

Tang S.M., WONG H.M.E., GUI H., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Comprehensive comparison of copy number variations detection using Illumina Omni 2.5M and Affymetrix CytoScan arrays, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 552T, Boston, Massachusetts, October 24, 2013.

Researcher : WEI R

List of Research Outputs

Lam S.S.Y., Wakuda T., Li Q., WEI R., ZHANG X., Chua S.E., Sham P.C., Takei N. and McAlonan G.M., Altered Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Autism, HUPO 2013.

Researcher : WONG HME

List of Research Outputs

CHENG G., Tang S.M., Wong H.M.E., Cheng W.C., So M.T., Miao X., ZHANG R., CUI L., Liu X., Ngan E.S.W., Lui V.C.H., Chung H.Y., Chan I.H.Y., Liu J.C., Zhong W., Xia H.M., Yu J.K., Qiu X., Wu X.Z., Wang B., Dong X., Tou J.F., Huang L.M., Yi B., Ren H.X., Chan E.K.W., Ye K., O'Reilly P.F., Wong K.K.Y., Sham P.C., Cherny S.S., Tam P.K.H. and Garcia-Barcelo M.M., Common genetic variants regulating ADD3 gene expression alter biliary atresia risk, Journal of Hepatology. 2013, 59(6): 1285-1291.

Tang S.M., WONG H.M.E., GUI H., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Comprehensive comparison of copy number variations detection using Illumina Omni 2.5M and Affymetrix CytoScan arrays, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 552T, Boston, Massachusetts, October 24, 2013.

WONG H.M.E., NG C.L., Lui V.C.H., So M.T., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Gene network analysis of candidate loci for human anorectal malformations. , PLoS One . 2013, 8(8): e69142.

WONG H.M.E., Ng C.L., Lui V.C.H., So M.T., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Gene network analysis of candidate loci for human anorectal malformations, 63nd Annual Meeting of the American Society of Human Genetics, Abstract 1027T. Boston, Massachusetts, October 24, 2013.

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : WONG HYG

List of Research Outputs

Chan K.W., CHAN K.S.K., Hui C.L.M., WONG H.Y.G., Chang W.C., Lee H.M.E., TANG Y.M. and Chen E.Y.H., Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: A longitudinal perspective, Psychiatry Research. 2014, 216 (2): 177-184.

Chan K.W., Hui C.L.M., WONG H.Y.G., Lee H.M.E., Chang W.C. and Chen E.Y.H., Medication adherence, knowledge about psychosis, and insight among patients with a schizophrenia-spectrum disorder, Journal of Nervous and Mental Disease. 2014, 202 (1): 25-29.

Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E., WONG H.Y.G. and Chen E.Y.H., Relationship between diminished expression and cognitive impairment in first-episode schizophrenia: A prospective three-year follow-up study, Schizophrenia Research. 2014, 152 (1): 146-151.

Hui C.L.M., WONG H.Y.G., TANG Y.M., Chang W.C., Chan K.W., Lee H.M.E., Lam M.L.M., Chiu C.P.Y., Law C.W., Chung D.W.S., Tso S., Pang E.P.F., Chan K.T., Wong Y.C., Mo F.Y.M., Chan K.P.M., Hung S.F., Honer W.G. and Chen E.Y.H., Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis, Schizophrenia Research. 2013, 150 (1): 297-302.

Researcher : WONG KL

List of Research Outputs

LIU A., Lau C.S.T., WONG K.L., Briscoe J., Hui C.C. and Ngan E.S.W., Dysregulation of Gli signaling underlies defective enteric nervous system development [poster], The 12th Annual Meeting of the International Society for Stem Cell Research, Vancouver, Canada, 18-21 June 2014.

Researcher : WONG SM

List of Research Outputs

Lam L.C.W., Chan W.C., WONG S.M., Chen E.Y.H., Ng R.M.K., Lee H.M.E., Chang W.C., Hung S.F., CHeung E.F.C., Sham P.C., Chiu H.F.K., Lam M., Chiang T.P., J van O.S., Lau J.T.F., Lewis G., Bebbington P. and The Hong Kong Mental Morbidity Survey Team #., The Hong Kong Mental Morbidity Survey: background and Study Design, East Asian Archives of Psychiatry. 2014, 24 (1): 30-36.

Researcher : WONG THG

List of Research Outputs

Chang R.C.C., Ho Y.S., WONG T.H.G., TSANG A.W.-.T., WUWONGSE S., POON C.H., YOU R., HUANG C., Ng T.W., CHENG S.Y., Hung C.H.L., LEUNG Y., Yang X., Law A.C.K., Chiu K., Lau W.M., Mak J.C.W., Wong G.T.C., Lee S.M.Y. and Hoi M.P.M., Investigating mechanisms of risk factors for Alzheimer’s disease to learn how to prevent disease progression., International Alzheimer’s Disease Conference 2014. 24.

WONG T.H.G., Hung C.H.L., TSANG A.W.-.T., Chang R.C.C. and Law A.C.K., Microtubule dysfunction in corticosterone and oligomeric beta-amyloid in vitro model and its effect on actin morphology., The 9th International Symposium of Healthy Aging. 2014, 50.

WUWONGSE S., CHENG S.Y., WONG T.H.G., Hung C.H.L., ZHANG Q., HO Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone and amyloid-beta on proteins essential for synaptic function: Implications for depression and Alzheimer's disease, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2013.

Researcher : WU HM

List of Research Outputs

Wong H.M.E., SO H.C., Li M., Wang Q., Butler W.L., BASIL P., WU H.M., Hui T.C.K., CHOI S.C., So M.T., Garcia-Barcelo M.M., McAlonan G.M., Chen E.Y.H., Cheung E.F.C., Chan R.C.K., Purcell S.M., Cherny S.S., Chen R.Y.L., Li T. and Sham P.C., Common Variants on Xq28 Conferring Risk of Schizophrenia in Han Chinese, Schizophrenia Bulletin. 2013.

Researcher : WUWONGSE S

List of Research Outputs

Chang R.C.C., Ho Y.S., WONG T.H.G., TSANG A.W.-.T., WUWONGSE S., POON C.H., YOU R., HUANG C., Ng T.W., CHENG S.Y., Hung C.H.L., LEUNG Y., Yang X., Law A.C.K., Chiu K., Lau W.M., Mak J.C.W., Wong G.T.C., Lee S.M.Y. and Hoi M.P.M., Investigating mechanisms of risk factors for Alzheimer’s disease to learn how to prevent disease progression., International Alzheimer’s Disease Conference 2014. 24.

WUWONGSE S., CHENG S.Y., WONG T.H.G., Hung C.H.L., ZHANG Q., HO Y.S., Law A.C.K. and Chang R.C.C., Effects of corticosterone and amyloid-beta on proteins essential for synaptic function: Implications for depression and Alzheimer's disease, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2013.

Researcher : Wong GHY

List of Research Outputs

Chang W.C., Hui C.L.M., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impacts of duration of untreated psychosis on cognition and negative symptoms in first-episode schizophrenia: a 3-year prospective follow-up study, Psychological Medicine. 2013, 43 (9): 1883-1893.

Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Symptomatic remission and cognitive impairment in first-episode schizophrenia: a prospective 3-year follow-up study, Journal of Clinical Psychiatry. 2013, 74 (11): e1046-1053.

Chang W.C., TANG Y.M., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., The relationship of early premorbid adjustment with negative symptoms and cognitive functions in first-episode schizophrenia: a prospective three-year follow-up study, Psychiatry Research. 2013, 209 (3): 353-360.

Hui C.L.M., Lau W.Y., Leung M.C., Chang W.C., TANG Y.M., Wong G.H.Y., Chan K.W., Lee H.M.E. and Chen E.Y.H., Clinical and social correlates of duration of untreated psychosis among adult-onset psychosis in Hong Kong Chinese: the JCEP study, Early Intervention in Psychiatry. 2013.

Hui C.L.M., TANG Y.M., Wong G.H.Y., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Predictors of help-seeking duration in adult-onset psychosis in Hong Kong, Social Psychiatry and Psychiatric Epidemiology. 2013, 48 (11): 1819-1828.

TANG Y.M., Chang W.C., Hui C.L.M., Wong G.H.Y., Chan K.W., Lee H.M.E., Yeung W.S., Wong C.K., Tang W.N., Chan W.F., Pang E.P.F., Tso S., Ng R.M.K., Hung S.F., Dunn E.L.W., Sham P.C. and Chen E.Y.H., Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study, Schizophrenia Research. 2014, 153 (1-3): 1-8.

Researcher : Wong HME

List of Research Outputs

Researcher : Wong JGWS

Project Title:	What makes a good clinical teacher in the new medical curriculum? A focus group study on student perception
Investigator(s):	Wong JGWS, Lam TP, Mak-Lieh F
Department:	Psychiatry
Source(s) of Funding:	Other Funding Scheme
Start Date:	01/2002

Project Title:	A follow-up study on the severity of psychological sequelae in SARS patients
Investigator(s):	Wong JGWS, Sham PC, Wong PC, McAlonan GM, Chu CM, Lee AM, Lee PWH, Tsang KWT, Chua SE
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	11/2004

List of Research Outputs

Chin W.Y., Lam C.L.K., Wong S.Y.S., Lo Y.C.Y., Fong D.Y.T., Lam T.P., Lee P.W.H., Wong J.G.W.S. and Chan T.Y., Findings of a longitudinal cohort study on depressive disorders in Hong Kong’s primary care, WONCA Asia Pacific 2014.

Leung A.Y.M., Chu D.W.S., Yung A., Wong J.G.W.S. and Law A.C.K., Depression care management programme in primary care setting: A pilot study, The Journal of Nutrition, Health & Aging. Springer Link, 2013, 17(1): S352.

Researcher : Wong MMC

Project Title:	Enrichment of collections in the library of the S.K. Yee Mental Health Resources and Rehabilitation Centre
Investigator(s):	Wong MMC, Mak KY, Mak-Lieh F, Yau EFY
Department:	Psychiatry
Source(s) of Funding:	S.K. Yee Medical Foundation - General Award
Start Date:	10/2001

Researcher : Wong MTH

List of Research Outputs

Chang R.C.C., Wuwongse S., Wong S., Wong M.T.H., TSANG A.W.-.T., Zhang E., CHENG S.Y., Hung C.H.L., Lau W.M., Ho Y.S., So K.F. and Law A.C.K., Investigating biological mechanisms of corticosterone-induced neurodegeneration: Implication of how depression promotes cognitive impairment in Alzheimer's disease, Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2013, 9 Issue 4 Supplement: 561-562.

Researcher : YAO N

List of Research Outputs

FUNG C.M.G., Cheung C., Chen E.Y.H., Lam C.A.R.M.E.N., Chiu C.I.N.D.Y., Law C.H.I.-.W.I.N.G., Leung M.K., Deng M.I.C.H.E.L.L.E., Cheung V.I.N.C.I., Li Q., YAO N., Tai K.S., Yip L.A.W.R.A.N.C.E., Suckling J.O.H.N., Sham P.C., McAlonan G.M. and Chua S.E., MRI predicts remission at 1 year in first-episode schizophrenia in females with larger striato-thalamic volumes, Neuropsychobiology. 2014, 69 (4): 243-248.

LI T.H., Yao N., Chua S.E., Ho S.L., Khong P.L. and Mak H.K.F., Li DTH, Yao N, Chua S, Ho SL, Khong PL, Mak HKF. Brain Iron Deposition in Parkinson’s Disease by High Resolution Susceptibility MR Phase Imaging. , 20th World Congress of Parkinson's Disease. 2013.

Researcher : YUNG KP

List of Research Outputs

Chung K.F., Yu Y.M.B., YUNG K.P., Yeung W.F., NG H.Y. and HO Y.Y.F., Assessment of fatigue using the Multidimensional Fatigue Inventory in patients with major depressive disorder, Comprehensive Psychiatry. 2014.

Chung K.F., Yeung W.F., HO Y.Y.F., Ho L.M. and YUNG K.P., Validity and reliability of the Brief Insomnia Questionnaire in the general population in Hong Kong, Journal of Psychiatric Research. 2014, 76 (5): 374-379.

Yeung W.F., Chung K.F., YUNG K.P. and NG H.Y., Doxepin for Insomnia: A Systematic Review of Randomized Placebo-controlled Trials, Sleep Medicine Reviews. 2014.

Researcher : Yao N

List of Research Outputs

Researcher : Yeung WF

Project Title:	A Systemic Review on the Effectiveness of Chinese Herbal Medicine for Depression
Investigator(s):	Yeung WF, Chung KF
Department:	Psychiatry
Source(s) of Funding:	Hospital Authority - General Award
Start Date:	02/2013

Project Title:	Use of Complementary and Alternative Medicine for Insomnia in Hong Kong
Investigator(s):	Yeung WF, Chung KF
Department:	Psychiatry
Source(s) of Funding:	Small Project Funding
Start Date:	06/2013
Completion Date:	08/2014

Project Title:	12th Meeting of the Consortium for Globalization of Chinese Medicine ; Utilization of Traditional Chinese Medicine and Other Complementary and Alternative Medicine for Improving Sleep in Hong Kong: A Telephone Survey
Investigator(s):	Yeung WF
Department:	Psychiatry
Source(s) of Funding:	URC/CRCG - Conference Support for Teaching Staff
Start Date:	08/2013
Completion Date:	08/2013

List of Research Outputs

Chung K.F., Yu Y.M.B., YUNG K.P., Yeung W.F., NG H.Y. and HO Y.Y.F., Assessment of fatigue using the Multidimensional Fatigue Inventory in patients with major depressive disorder, Comprehensive Psychiatry. 2014.

Chung K.F., Kan K.K.K. and Yeung W.F., Insomnia in adolescents: prevalence, help-seeking behaviors, and types of interventions, Child and Adolescent Mental Health. 2014, 19 (1): 57-63.

Chung K.F., Yeung W.F., HO Y.Y.F., Ho L.M. and YUNG K.P., Validity and reliability of the Brief Insomnia Questionnaire in the general population in Hong Kong, Journal of Psychiatric Research. 2014, 76 (5): 374-379.

Gadau M., Yeung W.F., Liu H., Zaslawski C., Tan Y.S., Wang F.C., Bangrazi S., Chung K.F., Bian Z.X. and Zhang S.P., Acupuncture and moxibustion for lateral elbow pain: a systematic review of randomized controlled trials, BMC Complementary and Alternative Medicine. 2014, 14.

HO Y.Y.F., Yeung W.F., Ng T.H. and Chan C.S., The efficacy and cost- effectiveness of stepped care prevention and treatment for depressive and/or anxiety disorders: A systematic review and meta-analysis., The Hong Kong Psychological Society Annual Conference 2014.

Yeung W.F., Chung K.F., Ng K.Y., Yu Y.M.B., Ziea E.T.C. and Ng B.F.L., A Systematic Review on the Efficacy, Safety and Types of Chinese Herbal Medicine for Depression, Journal of Psychiatric Research. 2014.

Yeung W.F., Chung K.F., Ng K.Y., Yu Y.M.B., Ziea E.T.C. and Ng B.F.L., A meta-analysis of the efficacy and safety of traditional Chinese medicine formula Ganmai Dazao decoction for depression, Journal of Ethnopharmacology. 2014, 153 (2): 309-317.

Yeung W.F., Chen H., Chung K.F. and Zhang Z., Clinical trials of traditional Chinese medicine for insomnia: current status and future directions, World Journal of Sleep Medicine. 2014, 1: 54-58.

Yeung W.F., Chung K.F., YUNG K.P. and NG H.Y., Doxepin for Insomnia: A Systematic Review of Randomized Placebo-controlled Trials, Sleep Medicine Reviews. 2014.

Researcher : Yu YMB

List of Research Outputs

Chung K.F., Yu Y.M.B., YUNG K.P., Yeung W.F., NG H.Y. and HO Y.Y.F., Assessment of fatigue using the Multidimensional Fatigue Inventory in patients with major depressive disorder, Comprehensive Psychiatry. 2014.

Yeung W.F., Chung K.F., Ng K.Y., Yu Y.M.B., Ziea E.T.C. and Ng B.F.L., A Systematic Review on the Efficacy, Safety and Types of Chinese Herbal Medicine for Depression, Journal of Psychiatric Research. 2014.

Yeung W.F., Chung K.F., Ng K.Y., Yu Y.M.B., Ziea E.T.C. and Ng B.F.L., A meta-analysis of the efficacy and safety of traditional Chinese medicine formula Ganmai Dazao decoction for depression, Journal of Ethnopharmacology. 2014, 153 (2): 309-317.

Researcher : ZHANG X

List of Research Outputs

Lam S.S.Y., Wakuda T., Li Q., WEI R., ZHANG X., Chua S.E., Sham P.C., Takei N. and McAlonan G.M., Altered Protein Expression of Rat Prefrontal Cortex following Perinatal Asphyxia: Implications of Schizophrenia and Autism, HUPO 2013.

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