DEPT OF PHARMACOLOGY & PHARMACY



Researcher : Au Yeung KW

List of Research Outputs

LIU W.Y., Au Yeung K.W., Ko J.K.S., Man R.Y.K. and Leung S.W.S., Astragalus Membranaceus (Huangqi) exerts differential angiogenic properties under physiological and pathological conditions, 5th International Meeting on Angiogenesis, 12-14 March 2014, Amsterdam, The Netherlands. 2014.


Researcher : BARETELLA OM

List of Research Outputs

BARETELLA O.M., Acidosis Prevents and Alkalosis Augments Endothelium-dependent Contractions, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
BARETELLA O.M., Xu A. and Vanhoutte P.M.G.R., Acidosis prevents and alkalosis augments endothelium-dependent contractions in mouse arteries, Pflugers Archiv : European journal of physiology. . 2013, Epub [2013 Jul 20].
BARETELLA O.M., Chung S.K., Barton M., Xu A. and Vanhoutte P.M.G.R., Obesity and heterozygous endothelial overexpression of prepro-endothelin-1 modulate responsiveness of mouse main and segmental renal arteries to vasoconstrictor agents., Life Sci. . 2014, Epub ahead of print.
Baretella O.M., Xu A. and Vanhoutte P.M.G.R., Contractions to endogenous and exogenous endothelin-1 in segmental renal arteries of the mouse: up-regulation in obesity, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Heterozygous Endothelial Endothelin-1 Overexpression Potentiates Endothelium-Dependent Contractions in the Carotid Arteries of Obese Mice, HBPR 2013, September 11-14, 2013, New Orleans, LA. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Heterozygous overexpression of preproendothelin-1 in endothelial cells enhances thromboxane-prostanoid receptor-induced contractions in the renal artery of obese mice, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Improved relaxations to acetylcholine in murine carotid arteries with heterozygous overexpression of preproendothelin-1 in the endothelium, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.


Researcher : Bai B

List of Research Outputs

Bai B., Liang Y., Xu C., Lee Y.K.M., Xu A., Wu D.H., Vanhoutte P.M.G.R. and Wang Y., CDK5-mediated hyperphosphorylation contributes to the lossof-SIRT1 function during the development of endothelial senescence, International Academy of Cardiology: 18th World congress on Heart Disease, Vancouver, Canada, July 26-29, 2013.
Bai B., Vanhoutte P.M.G.R. and Wang Y., Loss-of-SIRT1 function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5. , Trends in Cardiovascular Medicine . 2013.
Liang Y., Huang B., Song E., Bai B. and Wang Y., Constitutive activation of AMPK α1 in vascular endothelium promotes high fat diet-induced fatty liver injury: role of cyclooxygenase-2 induction., British Journal of Pharmacology. 2014, 171: 498-508.


Researcher : Baretella OM

List of Research Outputs

BARETELLA O.M., Acidosis Prevents and Alkalosis Augments Endothelium-dependent Contractions, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
BARETELLA O.M., Xu A. and Vanhoutte P.M.G.R., Acidosis prevents and alkalosis augments endothelium-dependent contractions in mouse arteries, Pflugers Archiv : European journal of physiology. . 2013, Epub [2013 Jul 20].
BARETELLA O.M., Chung S.K., Barton M., Xu A. and Vanhoutte P.M.G.R., Obesity and heterozygous endothelial overexpression of prepro-endothelin-1 modulate responsiveness of mouse main and segmental renal arteries to vasoconstrictor agents., Life Sci. . 2014, Epub ahead of print.
Baretella O.M., Xu A. and Vanhoutte P.M.G.R., Contractions to endogenous and exogenous endothelin-1 in segmental renal arteries of the mouse: up-regulation in obesity, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Heterozygous Endothelial Endothelin-1 Overexpression Potentiates Endothelium-Dependent Contractions in the Carotid Arteries of Obese Mice, HBPR 2013, September 11-14, 2013, New Orleans, LA. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Heterozygous overexpression of preproendothelin-1 in endothelial cells enhances thromboxane-prostanoid receptor-induced contractions in the renal artery of obese mice, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Improved relaxations to acetylcholine in murine carotid arteries with heterozygous overexpression of preproendothelin-1 in the endothelium, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.


Researcher : CAI Y

List of Research Outputs

CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Knockdown of Repressor Activator Protein 1 (Rap1) Suppresses NFKB-Dependent Inflammation in Human Macrophages, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Mice Lacking Prostaglandin E Receptor Subtype 4 Resist Diet-Induced Obesity Despite Hypertriglyceridemia, Arteriosclerosis, Thrombosis and Vascular Biology 2014, May 1-3, 2014, Toronto, Canada. 2014.
CAI Y. and Wang Y., Modulation of SIRT1 activity in adipose tissue affects mitochondrial function, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Role of prostaglandin E receptor subtype 4 (EP4) in the regulation of triglyceride metabolism, Seventeenth Annual Scientific Meeting, The Institute of Cardiovascular Science and Medicine, November 23, 2014, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Telomere-independent Rap1, modulates NF-kB-dependent inflammation in macrophages, 12th Meeting of the Asia Pacific Federation of Pharmacologists & Joint Meeting of Pharmacology of Chinese Pharmacological Society and Hong Kong Pharmacology Society, Shanghai, July 9-13, 2013. S11.3 (Acta Pharmacologica Sinica, Volume 34 Supplement, July 2013). 2013.


Researcher : CAI Y

List of Research Outputs

CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Knockdown of Repressor Activator Protein 1 (Rap1) Suppresses NFKB-Dependent Inflammation in Human Macrophages, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Mice Lacking Prostaglandin E Receptor Subtype 4 Resist Diet-Induced Obesity Despite Hypertriglyceridemia, Arteriosclerosis, Thrombosis and Vascular Biology 2014, May 1-3, 2014, Toronto, Canada. 2014.
CAI Y. and Wang Y., Modulation of SIRT1 activity in adipose tissue affects mitochondrial function, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Role of prostaglandin E receptor subtype 4 (EP4) in the regulation of triglyceride metabolism, Seventeenth Annual Scientific Meeting, The Institute of Cardiovascular Science and Medicine, November 23, 2014, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Telomere-independent Rap1, modulates NF-kB-dependent inflammation in macrophages, 12th Meeting of the Asia Pacific Federation of Pharmacologists & Joint Meeting of Pharmacology of Chinese Pharmacological Society and Hong Kong Pharmacology Society, Shanghai, July 9-13, 2013. S11.3 (Acta Pharmacologica Sinica, Volume 34 Supplement, July 2013). 2013.


Researcher : CHEN J

List of Research Outputs

CHEN J., Xu A., Lam K.S.L., Liu J. and Wang Y., Adiponectin deficiency promotes the development of metaplastic breast cancer-focusing on dysregulated T-cell function, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
CHEN J., Adipose-derived Stromal Cells Isolated from Adiponectin Deficient Mice Promote the Development of Metaplastic Mammary Tumors, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CHEN J. and Wang Y., Metaplastic breast cancer – a rare but challenging entity. , Trends in Cancer Research. 2013, 9: 65-71.
Liu J., Xu A., Lam K.S.L., Wong N.S., CHEN J., Shepherd P.R. and Wang Y., Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation, Oncotarget . 2013, 4: 1804-18.


Researcher : CHEN S

List of Research Outputs

CHEN S., Tong H.H.Y. and Kwok P.C.L., Spray dried oleanolic acid powder for pulmonary delivery, The 5th Asian Arden Conference, Aichi Gakuin University, Nagoya, Japan, 5-6 August 2013.


Researcher : CHEUNG C

List of Research Outputs

CHEUNG C., The Mechanism of Action of Xinmailong, A Proprietary Chinese Medicine Used in the Treatment of Heart Failure, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.


Researcher : CHOW YT

List of Research Outputs

LIANG W., Kwok P.C.L., CHOW Y.T., Tang P., Mason A.J., Chan H.K. and Lam J.K.W., Formulation of pH responsive peptide as inhalable dry powder for pulmonary delivery of nucleic acids, European Journal of Pharmaceutics and Biopharmaceutics . 2014, 86: 64.


Researcher : CHUI SLC

List of Research Outputs

CHUI S.L.C., An Investigation of the Association between Retinal Detachment and Oral Fluoroquinolones: A Self-controlled Case Series Study, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CHUI S.L.C., Man K.C.K., Cheng C.L., Chan E.W., LAU C.Y., Cheng V.C.C., Wong D.S.H., Yan-Kao Y.E. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. , J Antimicrobial chemotherapy.. 2014.
Chui S.L.C., Man K.C.K., Cheng C.L., Chan E.W., Lau C.Y., Cheng V.C.C., Wong D.S.H., Yang-Kao Y.H. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: A self-controlled case series study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 151.
HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
Leung P.S.C., Man K.C.K., Chui S.L.C., Chan E.W. and Tsui M.S.H., A retrospective study of medical staff manpower and service demand in a Hong Kong Accident and Emergency Department. , 15th International Conference on Emergency Medicine (ICEM 2014), 10-14 June 2014, Wan Chai Conference and Convention Centre. 2014.
Man K.C.K., Ip P., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W., Chow C., Yung A. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder Drug Prescribing Trend is Increasing Among Children and Adolescents in Hong Kong: 2001-2012, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
Man K.C.K., P L.P., Hsia Y.F., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A. and Wong I.C.K., Attention-deficit/hyperactivity disorder drug prescribing trend is increasing among children and adolescents in Hong Kong, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 141.
WONG Y.S., Chan E.W., CHUI S.L.C., SUTCLIFFE A.G. and Wong I.C.K., The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature., Public Health Nutrition. 2013, 17(11): 2605-2618.


Researcher : Chan EW

Project Title:Pharmacoepidmiology study of medication errors
Investigator(s):Chan EW, Wong ICK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012
Completion Date:06/2014


Project Title:The Renaissance of Pharmacovigilance; Safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis/Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy
Investigator(s):Chan EW
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


Project Title:Young adult patient experiences in clinical management of ADHD in Hong Kong
Investigator(s):Chan EW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Janssen Pharmaceutica - General Award
Start Date:01/2014


Project Title:Intramuscular olanzapine versus haloperidol or midazolam for the management of acute agitation in the emergency department  a multicentre randomised clinical trial.
Investigator(s):Chan EW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Early Career Scheme (ECS)
Start Date:01/2014


List of Research Outputs

CHUI S.L.C., Man K.C.K., Cheng C.L., Chan E.W., LAU C.Y., Cheng V.C.C., Wong D.S.H., Yan-Kao Y.E. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. , J Antimicrobial chemotherapy.. 2014.
Chan E.W., Atrial fibrillation in Hong Kong and considerations for the choice of pharmacotherapy. , Hospital Authority Head Office. 2014.
Chan E.W., Drug research development and the role of the pharmacist, 藥物科研及發展:藥物安全及藥劑師的角色, RTHK. 2013.
Chan E.W., Early Career Scheme Award: Research Grants Council, Hong Kong, Research Grants Council, Hong Kong. 2013.
Chan E.W., Fellowship, Society of Hospital Pharmacists of Australia (SHPA) . 2013.
Chan E.W., Joint media release, Pharmacists in Primary Care, Hong Kong Pharmacy Conference 2014. 2014.
Chan E.W., Local trends and safety considerations for NOACs., Pfizer expert panel meeting.. 2013.
Chan E.W., Leung L.P., Tsui M.S.H., Ho H.K., Wong C.K., Kong D.C.M., Taylor D.M.C.D., Knott J.C. and Wong I.C.K., Management of acute agitation in the Accident and Emergency setting: A survey of practice in Hong Kong. , 15th International Conference on Emergency Medicine (ICEM 2014), 10-14 June 2014, Wan Chai Conference and Convention Centre. 2014.
Chui S.L.C., Man K.C.K., Cheng C.L., Chan E.W., Lau C.Y., Cheng V.C.C., Wong D.S.H., Yang-Kao Y.H. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: A self-controlled case series study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 151.
HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
HE Y., LAU C.Y., Chan E.W., Man K.C.K., Cheng V.C. and Wong I.C.K., High-Versus-Low-Dose Histamine-2 antagonists for the Prophylaxis of Non-Steroidal Anti-Inflammatory Drug-Associated Gastrointestinal Ulcers, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
He Y., Chan E.W., Cheng V.C.C., Lau C.Y., Man K.C.K. and Wong I.C.K., High-versus-low-dose histamine-2 antagonists for the prophylaxis of non-steroidal anti-inflammatory drug-associated gastrointestinal ulcers, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 170.
Hsu W.W.Q., Sing C.W., He Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy., CNS drugs. 2013.
Hsu W.W.Q., Sing C.W., HE Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy. , International Society of Pharmacovigilance XIII meeting, Pisa, October 1-4 International Society for Pharmacoepidemiology (ISPE) 8th Asian Conference on Pharmacoepidemiology; The University of Hong Kong, 25-27 October. 2013.
Leung P.S.C., Man K.C.K., Chui S.L.C., Chan E.W. and Tsui M.S.H., A retrospective study of medical staff manpower and service demand in a Hong Kong Accident and Emergency Department. , 15th International Conference on Emergency Medicine (ICEM 2014), 10-14 June 2014, Wan Chai Conference and Convention Centre. 2014.
Man K.C.K., Ip P., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W., Chow C., Yung A. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder Drug Prescribing Trend is Increasing Among Children and Adolescents in Hong Kong: 2001-2012, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
Man K.C.K., Chan E.W., Douglas I., Ip P., Wong W.H.S., Coghill D. and Wong I.C.K., Attention-Deficit/Hyperactivity disorder (ADHD) Pharmacological Treatment and its Effect on Accident and Emergency Admission due to injury: a self-controlled case series study., 3rd EUNETHYDIS, Istanbul, Turkey, 21-24 May . 2014.
Man K.C.K., P L.P., Hsia Y.F., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A. and Wong I.C.K., Attention-deficit/hyperactivity disorder drug prescribing trend is increasing among children and adolescents in Hong Kong, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 141.
WONG Y.S., Hsia Y.F., Chan E.W., Murphy D.G.M., Simonoff E., Buitelaar J.K. and Wong I.C.K., The Variation of Psychopharmacological Prescription Rates for People With Autism Spectrum Disorder (ASD) in 30 Countries, Autism Research. 2014, n/a-n/a.
WONG Y.S., Chan E.W., CHUI S.L.C., SUTCLIFFE A.G. and Wong I.C.K., The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature., Public Health Nutrition. 2013, 17(11): 2605-2618.
Wong Y.S., Hsia Y.F., Chan E.W. and Wong I.C.K., The variation of psychopharmacological treatment for people with autistic spectrum disorder (ASD): an international study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 160.


Researcher : Chan HK

List of Research Outputs

D'Addio S.M., Chan J.G.Y., Kwok P.C.L., Benson B.R., Prud'homme R.K. and Chan H.K., Aerosol delivery of nanoparticles in uniform mannitol carriers formulated by ultrasonic spray freeze drying, Pharmaceutical Research. Springer US, 2013, 30: 2891-2901.
Kwok P.C.L. and Chan H.K., Delivery of inhalation drugs to children for asthma and other respiratory diseases, Advanced Drug Delivery Reviews. Elsevier, 2014, 73: 83-88.
Kwok P.C.L. and Chan H.K., Guest editor, Therapeutic Delivery. 2013, 4.
Kwok P.C.L. and Chan H.K., Nanotechnology versus other techniques in improving drug dissolution, Current Pharmaceutical Design. Bentham Science, 2014, 20: 474-482.
Kwok P.C.L. and Chan H.K., Pulmonary drug Delivery, Therapeutic Delivery. Future Science, 2013, 4: 877-878.
Wong J., Kwok P.C.L., Fathi A., Dehghani F. and Chan H.K., Crystallinity and electrostatic charge in inhalable salbutamol sulphate powder aerosols, Drug Delivery Australia 2013, The Woolcock Institute of Medical Research, Sydney, Australia, 24-25 October 2013.
Wong J., Chan H.K. and Kwok P.C.L., Electrostatics in pharmaceutical aerosols for inhalation, Therapeutic Delivery. 2013, 4: 981-1002.
Wong J., Yang M.Y., Kwok P.C.L., Leung S.S.Y. and Chan H.K., Measuring bipolar charge from commercial DPIs using the BOLAR™, In: Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM, Traini D, Respiratory Drug Delivery 2014, Fajardo, Puerto Rico, 4-8 May 2014. River Grove, IL, USA, Davis Healthcare International Publishing, 3: 727-730.
Wong J., Leung S., Kwok P.C.L., Prud'homme R.K. and Chan H.K., Novel porous mannitol carriers for pulmonary delivery of cyclosporine nanoparticles, Asian Federation for Pharmaceutical Sciences Conference 2013, Jeju, South Korea, 20-22 November, 2013.


Researcher : Chan KYC

List of Research Outputs

Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.


Researcher : Chan WLP

List of Research Outputs

Chan W.L.P., Chu K.P.J. and Wong K.C., Introduction to Problem-based Learning, China Pharmaceutical University. 中國藥科大學, 2014.
Chan W.L.P., Ling M., Lee C.P., Ng T.F., Lam E., Li W.Y., Yung C.H.J., Chan K.C. and Ng E., Plenery Session - Young Pharmacists Forum, Hong Kong Pharmacy Conference 2014. 2014.
Chan W.L.P., Chung C.K. and Wong V., Therapeutic Debate, Hong Kong Pharmacy Conference 2014. 2014.


Researcher : Chan WYE

Project Title:Pharmacoepidmiology study of medication errors
Investigator(s):Chan EW, Wong ICK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012
Completion Date:06/2014


Project Title:The Renaissance of Pharmacovigilance; Safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis/Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy
Investigator(s):Chan EW
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


Project Title:Young adult patient experiences in clinical management of ADHD in Hong Kong
Investigator(s):Chan EW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Janssen Pharmaceutica - General Award
Start Date:01/2014


Project Title:Intramuscular olanzapine versus haloperidol or midazolam for the management of acute agitation in the emergency department  a multicentre randomised clinical trial.
Investigator(s):Chan EW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Early Career Scheme (ECS)
Start Date:01/2014


List of Research Outputs



Researcher : Che CM

Project Title:Blue light photoluminescent materials
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:Hung Hing Ying Physical Sciences Research Fund
Start Date:02/1999


Project Title:Research and development of luminescent biosensors for drug screening and environmental monitoring
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:11/2002


Project Title:Functional nanomaterials research
Investigator(s):Che CM, Chan MCW
Department:Chemistry
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Green Chemistry: Application of Nanotechnology in the Development of Highly Efficient and Environmental Friendly Chemical Synthesis
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:04/2009


Project Title:Green Chemistry: Application of Nanotechnology in the Development of Highly Efficient and Environmental Friendly Chemical Synthesis
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:04/2009


Project Title:Transition Metal-Catalysed Oxygenation Reactions. Biomimetic and Photochemical Approaches
Investigator(s):Che CM, Wong ELM, Guo Z, Ng KM
Department:Chemistry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2011
Completion Date:12/2013


Project Title:Solvent-Free Metal Nanoparticle-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry: Applications of Noble Metal Nanoparticles to the Molecular Imaging of Herbal Tissues, and Investigation of the Ion Desorption Mechanism(s)
Investigator(s):Che CM, Ng KM
Department:Chemistry
Source(s) of Funding:General Research Fund (GRF)
Start Date:08/2011


Project Title:Metal-organic materials and prototype device for organic photovoltaic cell application
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:04/2012
Completion Date:10/2013


Project Title:Metal-organic materials and prototype device for organic photovoltaic cell application (ITS/310/11)
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:04/2012
Completion Date:10/2013


Project Title:Long-Lived Triplet Excited States for Water Oxidation and Carbon Dioxide Reduction
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:CAS - Croucher Funding Scheme for Joint Laboratories
Start Date:10/2012


Project Title:R&D Laboratory for Testing of Chinese Medicine
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:The Hong Kong Jockey Club Charities Trust - General Award
Start Date:11/2012


Project Title:Molecular Design of New Classes of Phosphorescent d8 Metal Complexes with Long-Lived Emissive Excited States and Application Studies in Photo-Catalysis, Luminescent Sensors, and Molecular Self-Assembly
Investigator(s):Che CM, Ma C
Department:Chemistry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Study on High-Valent Iridium Complexes: Synthesis, Characterization and Reactivity towards Oxidative C-H Bond Functionalization
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2013
Completion Date:12/2013


Project Title:Medicinal Chemistry of Gold Complexes
Investigator(s):Che CM, Sun RWY
Department:Chemistry
Source(s) of Funding:Germany/Hong Kong Joint Research Scheme
Start Date:01/2013


Project Title:Therapeutic applications of timosaponins and their synthetic derivatives
Investigator(s):Che CM, Sy LK, Lok CN
Department:Chemistry
Source(s) of Funding:Innovation and Technology Support Programme (Tier 3)
Start Date:03/2013
Completion Date:08/2014


Project Title:Phosphorescent Metal Complexes for Solar Energy Conversion Reactions
Investigator(s):Che CM, Phillips DL
Department:Chemistry
Source(s) of Funding:SRFDP & RGC ERG Joint Research Scheme
Start Date:03/2013


Project Title:Therapeutic Applications of Timosaponins and Their Synthetic Derivatives
Investigator(s):Che CM, Sy LK, Lok CN
Department:Chemistry
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:05/2013


Project Title:Drug
Investigator(s):Che CM, Guan X, Wong AST
Department:Chemistry
Source(s) of Funding:Seed Funding for Strategic Research Theme
Start Date:06/2013


Project Title:Transition Metal-Catalyzed Oxidative C-H Functionalization. Reactive Metal-Oxygen and Metal-Nitrogen Multiple Bonded Complexes and Photochemical Catalysis
Investigator(s):Che CM, Lo KY, Guan X
Department:Chemistry
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2013


Project Title:Therapeutic Applications of Timosaponins and Their Synthetic Derivatives
Investigator(s):Che CM, Sy LK, Lok CN
Department:Chemistry
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2013


Project Title:Chiral Iron(II) Complexes Catalyzed Highly Enantioselective cis-Dihydroxylation of Alkenes with Hydrogen Peroxide as Terminal Oxidant and Alkenes in Limiting Amount
Investigator(s):Che CM
Department:Chemistry
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2014


Project Title:Research and development of phenanthrenes from Chinese medicine for therapeutic use
Investigator(s):Che CM, Sy LK, Lok CN
Department:Chemistry
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:01/2014


Project Title:Therapeutic Applications of Timosaponins and Their Synthetic Derivatives
Investigator(s):Che CM, Sy LK, Lok CN
Department:Chemistry
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2014


List of Research Outputs

Tong S.M., Chow P.K., To W.P., Che C.M. and Kwok W.M., A Theoretical Investigation into The Luminescent Properties Of d8-Transition-Metal Complexes With Tetradentate Schiff Base Ligands, Chemistry - A European Journal. 2014, 20: 6433-6443.


Researcher : Cho CH

Project Title:Advances in GI Pharmacology - From Acid Secretion to Mucosal Protection Symposium Non-ulcerogenic Dose of Dexamethasone Delays Gastric Ulcer Healing in Rats
Investigator(s):Cho CH
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2004


Project Title:Adrenaline and its receptor activation on colon cancer growth
Investigator(s):Cho CH
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2006




Researcher : Chu KPJ

List of Research Outputs

Chan W.L.P., Chu K.P.J. and Wong K.C., Introduction to Problem-based Learning, China Pharmaceutical University. 中國藥科大學, 2014.


Researcher : Chui SLC

List of Research Outputs

CHUI S.L.C., An Investigation of the Association between Retinal Detachment and Oral Fluoroquinolones: A Self-controlled Case Series Study, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CHUI S.L.C., Man K.C.K., Cheng C.L., Chan E.W., LAU C.Y., Cheng V.C.C., Wong D.S.H., Yan-Kao Y.E. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. , J Antimicrobial chemotherapy.. 2014.
Chui S.L.C., Man K.C.K., Cheng C.L., Chan E.W., Lau C.Y., Cheng V.C.C., Wong D.S.H., Yang-Kao Y.H. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: A self-controlled case series study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 151.
HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
Leung P.S.C., Man K.C.K., Chui S.L.C., Chan E.W. and Tsui M.S.H., A retrospective study of medical staff manpower and service demand in a Hong Kong Accident and Emergency Department. , 15th International Conference on Emergency Medicine (ICEM 2014), 10-14 June 2014, Wan Chai Conference and Convention Centre. 2014.
Man K.C.K., Ip P., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W., Chow C., Yung A. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder Drug Prescribing Trend is Increasing Among Children and Adolescents in Hong Kong: 2001-2012, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
Man K.C.K., P L.P., Hsia Y.F., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A. and Wong I.C.K., Attention-deficit/hyperactivity disorder drug prescribing trend is increasing among children and adolescents in Hong Kong, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 141.
WONG Y.S., Chan E.W., CHUI S.L.C., SUTCLIFFE A.G. and Wong I.C.K., The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature., Public Health Nutrition. 2013, 17(11): 2605-2618.


Researcher : Chung CK

List of Research Outputs

Chan W.L.P., Chung C.K. and Wong V., Therapeutic Debate, Hong Kong Pharmacy Conference 2014. 2014.


Researcher : DETREMMERIE CMS

List of Research Outputs

DETREMMERIE C.M.S., Leung S.W.S., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., The endothelium-dependent, soluble guanylyl cyclase-dependent augmentation caused by thymoquinone in isolated porcine coronary arteries is mediated by cIMP, Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
DETREMMERIE C.M.S., Leung S.W.S., Xu A., Alkharfy K. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation depending on activation of soluble guanylyl cyclase in isolated arteries, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.
Leung S.W.S., DETREMMERIE C.M.S., LI Z., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation of contraction depending on activation of soluble guanylyl cyclase in isolated arteries, 11th International Symposium on Mechanisms of Vasodilatation, 3 to 7 Oct 2013, Zurich, Switzerland. 2013.


Researcher : Deng H

List of Research Outputs

Cheung B.M.Y. and Deng H., Fibroblast growth factor 21: a promising therapeutic target in obesity-related diseases., Expert Rev Cardiovasc Ther.. 2014, 12(6): 659-66.
Deng H., Huang B., Lee I.K., Park S. and Xu A., Clusterin facilitates production and secretion of high molecular weight adponectin, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.
Zeng W.W., Deng H., Chu T.T.W. and Tomlinson B., Comparison of a Low Dose Bisoprolol/Hydrochlorothiazide Combination with Valsartan in the Treatment of Hypertension, The 10th Asia Pacific Congress of Hypertension. 2014.


Researcher : Dufay S

Project Title:Quantitation of Dexmedetomidine in plasma for pharmacokinetic study after intranasal administration in healthy volunteers
Investigator(s):Dufay S, Irwin MG, Wong ICK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:13th ISoP Annual Meeting "The Renaissance of Pharmacovigilance"; Reduction of toxicity of Traditional Chinese Medicine Aconite in the domestic setting./Comparison of Biosimilar Guidelines: Impact on Patient Safety
Investigator(s):Dufay S
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


List of Research Outputs

Dufay S. and Worsley A.J., Comparison of Biosimilar Guidelines: Impact on Patient Safety, International Society of Pharmacovigilance. 2013.
Dufay S. and Worsley A.J., Reduction of toxicity of Traditional Chinese Medicine Aconite in the domestic setting., International Society of Pharmacovigilance. 2013.


Researcher : FAN P

List of Research Outputs

SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
SONG E., Fan P., Huang B., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice, J Am Heart Assoc.. 2014, 3: e000837.
SONG E., FAN P., Xu A., Feletou M., Vilaine J.P., Vanhoutte P.M.G.R. and Wang Y., Elevated 20-HETE contributes to the improved endothelial function in llpocalin-2 deficient mice, The 12th Meeting of the Asia Pacific Federation of Pharmacologists, Shanghai China, July 9-13, 2013.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.
Xu C., Fan P., Xu A., Vanhoutte P.M.G.R. and Wang Y., Biotin deficiency mimics the beneficial effects of calorie restriction by regulating SIRT1 and acetyl-coA carboxylase 2 in the adipose tissues, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.


Researcher : Fan P

List of Research Outputs

SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
SONG E., Fan P., Huang B., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice, J Am Heart Assoc.. 2014, 3: e000837.
SONG E., FAN P., Xu A., Feletou M., Vilaine J.P., Vanhoutte P.M.G.R. and Wang Y., Elevated 20-HETE contributes to the improved endothelial function in llpocalin-2 deficient mice, The 12th Meeting of the Asia Pacific Federation of Pharmacologists, Shanghai China, July 9-13, 2013.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.
Xu C., Fan P., Xu A., Vanhoutte P.M.G.R. and Wang Y., Biotin deficiency mimics the beneficial effects of calorie restriction by regulating SIRT1 and acetyl-coA carboxylase 2 in the adipose tissues, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.


Researcher : HE Y

List of Research Outputs

HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
HE Y., LAU C.Y., Chan E.W., Man K.C.K., Cheng V.C. and Wong I.C.K., High-Versus-Low-Dose Histamine-2 antagonists for the Prophylaxis of Non-Steroidal Anti-Inflammatory Drug-Associated Gastrointestinal Ulcers, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
HE Y., Investigation of High-dose Versus Low-dose Histamine-2 antagonists on the Prophylaxis of Gastrointestinal Ulcers in Patients Receiving Non-Steroidal Anti-inflammatory Drugs, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
He Y., Chan E.W., Cheng V.C.C., Lau C.Y., Man K.C.K. and Wong I.C.K., High-versus-low-dose histamine-2 antagonists for the prophylaxis of non-steroidal anti-inflammatory drug-associated gastrointestinal ulcers, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 170.
Hsu W.W.Q., Sing C.W., He Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy., CNS drugs. 2013.
Hsu W.W.Q., Sing C.W., HE Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy. , International Society of Pharmacovigilance XIII meeting, Pisa, October 1-4 International Society for Pharmacoepidemiology (ISPE) 8th Asian Conference on Pharmacoepidemiology; The University of Hong Kong, 25-27 October. 2013.


Researcher : He Y

List of Research Outputs

HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
HE Y., LAU C.Y., Chan E.W., Man K.C.K., Cheng V.C. and Wong I.C.K., High-Versus-Low-Dose Histamine-2 antagonists for the Prophylaxis of Non-Steroidal Anti-Inflammatory Drug-Associated Gastrointestinal Ulcers, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
HE Y., Investigation of High-dose Versus Low-dose Histamine-2 antagonists on the Prophylaxis of Gastrointestinal Ulcers in Patients Receiving Non-Steroidal Anti-inflammatory Drugs, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
He Y., Chan E.W., Cheng V.C.C., Lau C.Y., Man K.C.K. and Wong I.C.K., High-versus-low-dose histamine-2 antagonists for the prophylaxis of non-steroidal anti-inflammatory drug-associated gastrointestinal ulcers, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 170.
Hsu W.W.Q., Sing C.W., He Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy., CNS drugs. 2013.
Hsu W.W.Q., Sing C.W., HE Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy. , International Society of Pharmacovigilance XIII meeting, Pisa, October 1-4 International Society for Pharmacoepidemiology (ISPE) 8th Asian Conference on Pharmacoepidemiology; The University of Hong Kong, 25-27 October. 2013.


Researcher : Hsia Y

List of Research Outputs

Hsia Y., Neubert A., Viner R. and Wong I.C.K., Anti-obesity drug prescribing in children and adolescents: a population-based study in the UK, Hong Kong Pharmaceutical Journal, 8th Asian Conference on Pharmacoepidemiology, October 25-27, 2013, Hong Kong. 2013, 20(3): 133.
Hsia Y., WONG Y.S., Murphy D.G., Simonoff E., Buitelaar J.K. and Wong I.C.K., Psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study., Psychopharmacology . 2013, 231: 999-1009.


Researcher : Hsu WWQ

List of Research Outputs

Hsu W.W.Q., Sing C.W., He Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy., CNS drugs. 2013.
Hsu W.W.Q., Sing C.W., HE Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy. , International Society of Pharmacovigilance XIII meeting, Pisa, October 1-4 International Society for Pharmacoepidemiology (ISPE) 8th Asian Conference on Pharmacoepidemiology; The University of Hong Kong, 25-27 October. 2013.


Researcher : Huang B

List of Research Outputs

Deng H., Huang B., Lee I.K., Park S. and Xu A., Clusterin facilitates production and secretion of high molecular weight adponectin, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
Liang Y., Huang B., Song E., Bai B. and Wang Y., Constitutive activation of AMPK α1 in vascular endothelium promotes high fat diet-induced fatty liver injury: role of cyclooxygenase-2 induction., British Journal of Pharmacology. 2014, 171: 498-508.
SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.


Researcher : Ko JKS

List of Research Outputs

LIU W.Y., Au Yeung K.W., Ko J.K.S., Man R.Y.K. and Leung S.W.S., Astragalus Membranaceus (Huangqi) exerts differential angiogenic properties under physiological and pathological conditions, 5th International Meeting on Angiogenesis, 12-14 March 2014, Amsterdam, The Netherlands. 2014.


Researcher : Kwok PCL

Project Title:Inhalable dry powder aerosols for influenza prevention or treatment
Investigator(s):Kwok PCL, Yen H, Peiris JSM
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012


Project Title:Inhalable oleanolic acid dry powder for lung diseases
Investigator(s):Kwok PCL
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2013


Project Title:The 5th Asian Arden Conference; Spray dried oleanolic acid powder for pulmonary delivery
Investigator(s):Kwok PCL
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:08/2013
Completion Date:08/2013


Project Title:Inhalable macromolecule dry powder for asthma treatment in children
Investigator(s):Kwok PCL, Lam JKW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Health and Medical Research Fund - Mini Grant
Start Date:01/2014


Project Title:Inhalable antimicrobial peptide dry powder for tuberculosis treatment
Investigator(s):Kwok PCL, Lam JKW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:04/2014


List of Research Outputs

CHEN S., Tong H.H.Y. and Kwok P.C.L., Spray dried oleanolic acid powder for pulmonary delivery, The 5th Asian Arden Conference, Aichi Gakuin University, Nagoya, Japan, 5-6 August 2013.
D'Addio S.M., Chan J.G.Y., Kwok P.C.L., Benson B.R., Prud'homme R.K. and Chan H.K., Aerosol delivery of nanoparticles in uniform mannitol carriers formulated by ultrasonic spray freeze drying, Pharmaceutical Research. Springer US, 2013, 30: 2891-2901.
Kwok P.C.L. and Chan H.K., Delivery of inhalation drugs to children for asthma and other respiratory diseases, Advanced Drug Delivery Reviews. Elsevier, 2014, 73: 83-88.
Kwok P.C.L., Electrostatics of pharmaceutical aerosols, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan, 7 August 2013. 2013.
Kwok P.C.L. and Chan H.K., Guest editor, Therapeutic Delivery. 2013, 4.
Kwok P.C.L., Inhalable dry powders for pulmonary nucleic acid delivery, The University of Sydney Pharmaceutical Student Symposium 2013, Faculty of Pharmacy, The University of Sydney, Australia, 16 August 2013. 2013.
Kwok P.C.L. and Chan H.K., Nanotechnology versus other techniques in improving drug dissolution, Current Pharmaceutical Design. Bentham Science, 2014, 20: 474-482.
Kwok P.C.L. and Chan H.K., Pulmonary drug Delivery, Therapeutic Delivery. Future Science, 2013, 4: 877-878.
LIANG W., Kwok P.C.L., CHOW Y.T., Tang P., Mason A.J., Chan H.K. and Lam J.K.W., Formulation of pH responsive peptide as inhalable dry powder for pulmonary delivery of nucleic acids, European Journal of Pharmaceutics and Biopharmaceutics . 2014, 86: 64.
MAN K.W.D., Kwok P.C.L. and Lam J.K.W., Self-assembled poly(ethylene glycol)-poly(D,L-lactic acid) nanoparticles modified with PEI as gene delivery carrier, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
Syed Muhammad S.A.F., Oubani H., Abbas A., Chan H.-.K., Kwok P.C.L. and Dehghani F., The production of dry powder by the sonocrystallisation for inhalation drug delivery, Powder Technology. 2013, 246: 337-344.
Wong J., Kwok P.C.L., Fathi A., Dehghani F. and Chan H.K., Crystallinity and electrostatic charge in inhalable salbutamol sulphate powder aerosols, Drug Delivery Australia 2013, The Woolcock Institute of Medical Research, Sydney, Australia, 24-25 October 2013.
Wong J., Chan H.K. and Kwok P.C.L., Electrostatics in pharmaceutical aerosols for inhalation, Therapeutic Delivery. 2013, 4: 981-1002.
Wong J., Yang M.Y., Kwok P.C.L., Leung S.S.Y. and Chan H.K., Measuring bipolar charge from commercial DPIs using the BOLAR™, In: Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM, Traini D, Respiratory Drug Delivery 2014, Fajardo, Puerto Rico, 4-8 May 2014. River Grove, IL, USA, Davis Healthcare International Publishing, 3: 727-730.
Wong J., Leung S., Kwok P.C.L., Prud'homme R.K. and Chan H.K., Novel porous mannitol carriers for pulmonary delivery of cyclosporine nanoparticles, Asian Federation for Pharmaceutical Sciences Conference 2013, Jeju, South Korea, 20-22 November, 2013.


Researcher : LAN Y

List of Research Outputs

Abbate V., LIANG W., Patel J., LAN Y., Capriotti L., Iacobucci V., Bui T.T., Chaudhuri P., Kudsiova L., Vermeer L.S., Chan P.F.L., Kong X., Drake A.F., Lam J.K.W., Bansal S.S. and Mason A.J., Manipulating the pH response of 2,3-diaminopropionic acid rich peptides mediate highly effective gene silencing with low-toxicity, Journal of Controlled Release . 2013, 172: 929-938.
LAN Y., Lam T.H., Siu G.K.H., Yam W.C., Mason A.J. and Lam J.K.W., In vitro and ex vivo activity of D-antimicrobial peptides against drug resistant mycobacterium tuberculosis, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.


Researcher : LAU CY

List of Research Outputs

CHUI S.L.C., Man K.C.K., Cheng C.L., Chan E.W., LAU C.Y., Cheng V.C.C., Wong D.S.H., Yan-Kao Y.E. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. , J Antimicrobial chemotherapy.. 2014.
Chui S.L.C., Man K.C.K., Cheng C.L., Chan E.W., Lau C.Y., Cheng V.C.C., Wong D.S.H., Yang-Kao Y.H. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: A self-controlled case series study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 151.
HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
HE Y., LAU C.Y., Chan E.W., Man K.C.K., Cheng V.C. and Wong I.C.K., High-Versus-Low-Dose Histamine-2 antagonists for the Prophylaxis of Non-Steroidal Anti-Inflammatory Drug-Associated Gastrointestinal Ulcers, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
He Y., Chan E.W., Cheng V.C.C., Lau C.Y., Man K.C.K. and Wong I.C.K., High-versus-low-dose histamine-2 antagonists for the prophylaxis of non-steroidal anti-inflammatory drug-associated gastrointestinal ulcers, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 170.


Researcher : LI Z

List of Research Outputs

LI Z., Wang Y., Man R.Y.K. and Vanhoutte P.M.G.R., Upregulation of heme oxygenase-1 potentiates EDH-type relaxations in the mesenteric artery of the spontaneously hypertensive rat, Am J Physio Heart Circ. Physiol. 2013, 305: H1471-H1483.
Leung S.W.S., DETREMMERIE C.M.S., LI Z., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation of contraction depending on activation of soluble guanylyl cyclase in isolated arteries, 11th International Symposium on Mechanisms of Vasodilatation, 3 to 7 Oct 2013, Zurich, Switzerland. 2013.
Leung S.W.S., LI Z., Alkharfy K. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent contractions depending on activation of soluble guanylyl cyclase in isolated rat arteries, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China. 2013.


Researcher : LIANG W

List of Research Outputs

Abbate V., LIANG W., Patel J., LAN Y., Capriotti L., Iacobucci V., Bui T.T., Chaudhuri P., Kudsiova L., Vermeer L.S., Chan P.F.L., Kong X., Drake A.F., Lam J.K.W., Bansal S.S. and Mason A.J., Manipulating the pH response of 2,3-diaminopropionic acid rich peptides mediate highly effective gene silencing with low-toxicity, Journal of Controlled Release . 2013, 172: 929-938.
LIANG W., Kwok P.C.L., CHOW Y.T., Tang P., Mason A.J., Chan H.K. and Lam J.K.W., Formulation of pH responsive peptide as inhalable dry powder for pulmonary delivery of nucleic acids, European Journal of Pharmaceutics and Biopharmaceutics . 2014, 86: 64.
LIANG W., Mason A.J., Chan H.K., Poon L.L.M. and Lam J.K.W., Formulation of siRNA with pH-responsive amphipathic peptides for inhalation against respiratory infectious diseases, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
LIANG W., Mason A.J. and Lam J.K.W., pH responsive amphipathic peptide mediated siRNA delivery in lung epithelial cells., Drug Delivery Australia, The Australian Chapter of the Controlled Release Society. 2013.


Researcher : LIU WY

List of Research Outputs

LIU W.Y., Au Yeung K.W., Ko J.K.S., Man R.Y.K. and Leung S.W.S., Astragalus Membranaceus (Huangqi) exerts differential angiogenic properties under physiological and pathological conditions, 5th International Meeting on Angiogenesis, 12-14 March 2014, Amsterdam, The Netherlands. 2014.
LIU W.Y., Auyeung K.K.W., Ko J.K.S., Man R.Y.K. and Leung S.W.S., The effect of Astragalus Membranaceus on pathological angiogenesis, Seventeenth Annual Scientific meeting of the Institute of Cardiovascular Science and Medicine, “Translating Advances in Science into Improvements in Cardiovascular Health, 23 Nov 2013, Hong Kong. 2013.


Researcher : Lam JKW

Project Title:Chitosan-based dry powder nasal formulation for delivering therapeutic peptides – development of technology platform for intranasal delivery study
Investigator(s):Lam JKW, Kwok PCL
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2012
Completion Date:03/2014


Project Title:The use of N-acetyl cysteine grafted chitosan as mucosal adjuvant in intranasal formulation of DNA vaccine
Investigator(s):Lam JKW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:04/2013


Project Title:King's/HKU Fellowship Awards 2013-14
Investigator(s):Lam JKW
Department:Pharmacology & Pharmacy
Source(s) of Funding:King's/HKU Fellowship Awards
Start Date:09/2013


Project Title:Intranasal Delivery of DNA Vaccine using Oligochitosan/PLGA Nanoparticles
Investigator(s):Lam JKW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2014


Project Title:Intravaginal delivery of antiretroviral drug using polymeric micelle gel formulation to prevent HIV infection
Investigator(s):Lam JKW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:04/2014


Project Title:Dry powder formulation of lorazepam for intranasal delivery (for the treatment of emergency seizures)
Investigator(s):Lam JKW, Wong ICK, Kwok PCL
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2014


List of Research Outputs

Abbate V., LIANG W., Patel J., LAN Y., Capriotti L., Iacobucci V., Bui T.T., Chaudhuri P., Kudsiova L., Vermeer L.S., Chan P.F.L., Kong X., Drake A.F., Lam J.K.W., Bansal S.S. and Mason A.J., Manipulating the pH response of 2,3-diaminopropionic acid rich peptides mediate highly effective gene silencing with low-toxicity, Journal of Controlled Release . 2013, 172: 929-938.
LAN Y., Lam T.H., Siu G.K.H., Yam W.C., Mason A.J. and Lam J.K.W., In vitro and ex vivo activity of D-antimicrobial peptides against drug resistant mycobacterium tuberculosis, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
LIANG W., Kwok P.C.L., CHOW Y.T., Tang P., Mason A.J., Chan H.K. and Lam J.K.W., Formulation of pH responsive peptide as inhalable dry powder for pulmonary delivery of nucleic acids, European Journal of Pharmaceutics and Biopharmaceutics . 2014, 86: 64.
LIANG W., Mason A.J., Chan H.K., Poon L.L.M. and Lam J.K.W., Formulation of siRNA with pH-responsive amphipathic peptides for inhalation against respiratory infectious diseases, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
LIANG W., Mason A.J. and Lam J.K.W., pH responsive amphipathic peptide mediated siRNA delivery in lung epithelial cells., Drug Delivery Australia, The Australian Chapter of the Controlled Release Society. 2013.
Lam J.K.W., Editorial Board Member, Journal of Drug Design and Research. 2014.
Lam J.K.W., Guest Reviewer, Journal of Biosciences and Medicines. 2014.
Lam J.K.W., Xu Y., Worsley A.J. and Wong I.C.K., Oral Transmucosal Drug Delivery for Paediatric Use. , Adv Drug Deliv Rev.. 2013, 73: 50-62.
Lam J.K.W., Pulmonary delivery of antiviral siRNA using pH responsive peptides for influenza, Global RNAi Carrier Initiative, Korea Institute of Science and Technology, Seoul, Korea. 2014.
Lam J.K.W., Pulmonary delivery of nucleic acids, Institute of Pharmaceutical Science (IPS) Seminar Series King's College London, UK. 2014.
Lam J.K.W., The use of antimicrobial peptides and therapeutic siRNA against Mycobacterium tuberculosis, Inhaled therapies for TB 2013 - The Tokyo University of Science, Japan. 2013.
MAN K.W.D., Kwok P.C.L. and Lam J.K.W., Self-assembled poly(ethylene glycol)-poly(D,L-lactic acid) nanoparticles modified with PEI as gene delivery carrier, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
XU Y., YE Y. and Lam J.K.W., Reversible permeability enhancement of DNA-loaded chitosan oligosaccharide nanoparticle across Calu-3 epithelial cell model for airway gene delivery, 40th Annual Meeting & Exposition of the Controlled Release Society, 21-24 July 2013. Hawaii, USA. 2013.


Researcher : Lam MPS

Project Title:An evaluation of the prescribing appropriateness of Hong Kong elderly and the prevalence of preventable drug related admissions to hospital
Investigator(s):Lam MPS, Cheung BMY, Wong ICK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Health and Medical Research Fund - Mini Grant
Start Date:01/2013


List of Research Outputs

Man K.C.K., Ip P., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W., Chow C., Yung A. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder Drug Prescribing Trend is Increasing Among Children and Adolescents in Hong Kong: 2001-2012, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
Man K.C.K., P L.P., Hsia Y.F., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A. and Wong I.C.K., Attention-deficit/hyperactivity disorder drug prescribing trend is increasing among children and adolescents in Hong Kong, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 141.


Researcher : Lau CY

List of Research Outputs

CHUI S.L.C., Man K.C.K., Cheng C.L., Chan E.W., LAU C.Y., Cheng V.C.C., Wong D.S.H., Yan-Kao Y.E. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. , J Antimicrobial chemotherapy.. 2014.
Chui S.L.C., Man K.C.K., Cheng C.L., Chan E.W., Lau C.Y., Cheng V.C.C., Wong D.S.H., Yang-Kao Y.H. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: A self-controlled case series study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 151.
HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
HE Y., LAU C.Y., Chan E.W., Man K.C.K., Cheng V.C. and Wong I.C.K., High-Versus-Low-Dose Histamine-2 antagonists for the Prophylaxis of Non-Steroidal Anti-Inflammatory Drug-Associated Gastrointestinal Ulcers, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
He Y., Chan E.W., Cheng V.C.C., Lau C.Y., Man K.C.K. and Wong I.C.K., High-versus-low-dose histamine-2 antagonists for the prophylaxis of non-steroidal anti-inflammatory drug-associated gastrointestinal ulcers, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 170.


Researcher : Lee YKM

List of Research Outputs

Bai B., Liang Y., Xu C., Lee Y.K.M., Xu A., Wu D.H., Vanhoutte P.M.G.R. and Wang Y., CDK5-mediated hyperphosphorylation contributes to the lossof-SIRT1 function during the development of endothelial senescence, International Academy of Cardiology: 18th World congress on Heart Disease, Vancouver, Canada, July 26-29, 2013.


Researcher : Leung GPH

Project Title:Cloning and characterization of novel equilibrative nucleoside transporter type 4 (ENT4)
Investigator(s):Leung GPH
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2005


Project Title:Inhibitory effect of emodin on nucleoside transporters: potential implication in cancer therapy
Investigator(s):Leung GPH
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:04/2012
Completion Date:09/2013


Project Title:Vascular protective effect of ADTM
Investigator(s):Leung GPH
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:Vascular protective effect of narirutin
Investigator(s):Leung GPH
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Kwok C.Y., Li C., Cheng H.L., Ng Y.F., Chan T.Y., Kwan Y.W., Leung G.P.H., Lee S.M.Y., Mok D.K.W., Yu P.H.F. and Chan S.W., Cholesterol lowering and vascular protective effects of ethanolic extract of dried fruit of Crataegus pinnatifida, hawthorn (Shan Zha), in diet-induced hypercholesterolaemic rat model, Journal of Functional Foods. Nethelands, ELSEVIER SCIENCE, 2013, 5: 1326-1335.
Li W.S.R. and Leung G.P.H., Vasodilatory Effect of Narirutin in rat mesenteric arteries and aortae, 11th International Symposium on Mechanisms of Vasodilatation, Univ Hosp Zurich, Zurich, Switzerland, 04-06 October, 2013 . 2013.
Li W.Y., Ng Y.F., Zhang H., Guo Z.D., Guo D.J., Kwan Y.W., Leung G.P.H., Lee S.M.Y., Yu P.H.F. and Chan S.W., Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis, Inflammopharmacology. 2014, 22: 127-134.
Wu J.H., Leung G.P.H., Kwan Y.W., Sham T.T., Tang J.Y., Wang Y.H., Wan J.B., Lee S.M.Y. and Chan S.W., Suppression of Diet-Induced Hypercholesterolaemia by Saponins from Panax notoginseng in Rats, Journal of Functional Foods . Nethelands, ELSEVIER SCIENCE, 2013, 5: 1159-1169.


Researcher : Leung SWS

Project Title:Vascular effects of milk casein
Investigator(s):Leung SWS
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2012
Completion Date:11/2013


Project Title:Effects of non-nucleoside and nucleoside reverse transcriptase inhibitors on vascular inflammation
Investigator(s):Leung SWS, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:11th International Symposium on Mechanisms of Vasodilatation; Thymoquinone causes endothelium-dependent augmentation of contraction depending on activation of soluble guanylyl cyclase in isolated arteries
Investigator(s):Leung SWS
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


Project Title:Therapeutic potential of herbal flavonoids in the management of chronic obstructive pulmonary disease
Investigator(s):Leung SWS, Mak JCW, Man RYK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:11/2013


Project Title:Regulation of endothelium-derived contracting factor release by nitric oxide
Investigator(s):Leung SWS, Man RYK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

DETREMMERIE C.M.S., Leung S.W.S., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., The endothelium-dependent, soluble guanylyl cyclase-dependent augmentation caused by thymoquinone in isolated porcine coronary arteries is mediated by cIMP, Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
DETREMMERIE C.M.S., Leung S.W.S., Xu A., Alkharfy K. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation depending on activation of soluble guanylyl cyclase in isolated arteries, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.
LIU W.Y., Au Yeung K.W., Ko J.K.S., Man R.Y.K. and Leung S.W.S., Astragalus Membranaceus (Huangqi) exerts differential angiogenic properties under physiological and pathological conditions, 5th International Meeting on Angiogenesis, 12-14 March 2014, Amsterdam, The Netherlands. 2014.
LIU W.Y., Auyeung K.K.W., Ko J.K.S., Man R.Y.K. and Leung S.W.S., The effect of Astragalus Membranaceus on pathological angiogenesis, Seventeenth Annual Scientific meeting of the Institute of Cardiovascular Science and Medicine, “Translating Advances in Science into Improvements in Cardiovascular Health, 23 Nov 2013, Hong Kong. 2013.
Leung S.W.S., DETREMMERIE C.M.S., LI Z., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation of contraction depending on activation of soluble guanylyl cyclase in isolated arteries, 11th International Symposium on Mechanisms of Vasodilatation, 3 to 7 Oct 2013, Zurich, Switzerland. 2013.
Leung S.W.S., LI Z., Alkharfy K. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent contractions depending on activation of soluble guanylyl cyclase in isolated rat arteries, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China. 2013.
Mokhtar S.S., Vanhoutte P.M.G.R., Leung S.W.S., Yusoi M.I., Sulaiman W.A.W., Saad A.Z.M., Suppian R. and Rasool A.H.G., Reduced expression of prostacyclin synthase and nitric oxide synthase in subcutaneous arteries of Type 2 diabetic patients, The Tohoku Journal of Experimental Medicine. 2013, 231: 217-222.
Shen K., Leung S.W.S., Huang Y., Hou M., Xu A., Wang Z. and Vanhoutte P.M.G.R., Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries, Biochem Pharmacol. 2014, Epub ahead of print.
YEUNG Y.T., LEE S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Prolonged exposure to lopinavir impairs endothelium-dependent hyperpolarization-mediated relaxation in rat mesenteric arteries, Journal of Cardiovascular Pharmacology. 2013, 62: 397-404.
Yeung D.K.Y., Pu Q., Man R.Y.K. and Leung S.W.S., Involvement of calcium.camodulin-dependent kinase II in the regulation of vascular tone in porcine coronary arteries, Seventeenth Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine “Translating advances in science into improvements in cardiovascular health”, 23 Nov 2013, Hong Kong. 2013.
ZHANG Y., Leung S.W.S. and Man R.Y.K., Anti-inflammatory effect of MIR-17-3P via NF-KB pathway in human endothelial cells, Seventeenth Annual Scientific Meeting, The Institute of Cardiovascular Science and Medicine, November 23, 2014, Hong Kong. 2013.
ZHANG Y., Leung S.W.S. and Man R.Y.K., Anti-inflammatory effect of miR-17-3p in human umbilical vein endothelial cells , Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
ZHANG Y., Leung S.W.S. and Man R.Y.K., Role of miR-17-3p in vascular inflammation, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.
ZHAO Y., Leung S.W.S. and Vanhoutte P.M.G.R., Activation of α1-adrenergic receptors causes thromboxane-prostanoid receptor desensitization in the aorta of the spontaneously hypertensive rat, Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
ZOU Q., Leung S.W.S. and Vanhoutte P.M.G.R., Endogenous acetylcholine contributes to mild hypothermia induced endothelium-dependent relaxations in the SHR aorta, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.


Researcher : Li WSR

List of Research Outputs

Li W.S.R. and Leung G.P.H., Vasodilatory Effect of Narirutin in rat mesenteric arteries and aortae, 11th International Symposium on Mechanisms of Vasodilatation, Univ Hosp Zurich, Zurich, Switzerland, 04-06 October, 2013 . 2013.


Researcher : Liang Y

List of Research Outputs

Bai B., Liang Y., Xu C., Lee Y.K.M., Xu A., Wu D.H., Vanhoutte P.M.G.R. and Wang Y., CDK5-mediated hyperphosphorylation contributes to the lossof-SIRT1 function during the development of endothelial senescence, International Academy of Cardiology: 18th World congress on Heart Disease, Vancouver, Canada, July 26-29, 2013.
Liang Y., Huang B., Song E., Bai B. and Wang Y., Constitutive activation of AMPK α1 in vascular endothelium promotes high fat diet-induced fatty liver injury: role of cyclooxygenase-2 induction., British Journal of Pharmacology. 2014, 171: 498-508.


Researcher : Lin Z

List of Research Outputs

Lin Z., Wu F., Lin S., Pan X., Jin L., Lu T., Shi L., Wang Y., Xu A. and Li X., Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice. , Journal of Hepatology. 2014, Epub ahead of print.


Researcher : Liu J

Project Title:Identification and characterization of tumor-initiating cells in non-small cell lung carcinoma
Investigator(s):Liu J, Wong MP
Department:Pathology
Source(s) of Funding:Small Project Funding
Start Date:02/2013
Completion Date:07/2014


List of Research Outputs

CHEN J., Xu A., Lam K.S.L., Liu J. and Wang Y., Adiponectin deficiency promotes the development of metaplastic breast cancer-focusing on dysregulated T-cell function, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
Liu J., Xu A., Lam K.S.L., Wong N.S., CHEN J., Shepherd P.R. and Wang Y., Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation, Oncotarget . 2013, 4: 1804-18.


Researcher : Lui WYV

List of Research Outputs

Tsang C.M., Cheung Y.C., Lui W.Y.V., Yip Y.L., Zhang G., LIN W., Cheung K.C.P., Feng Y. and Tsao G.S.W., Berberine suppresses tumorigenicity and growth of nasopharyngeal carcinoma cells by inhibiting STAT3 activation induced by tumor associated fibroblasts, BMC Cancer. 2013, 13: 619.


Researcher : MAN KWD

List of Research Outputs

MAN K.W.D., Kwok P.C.L. and Lam J.K.W., Self-assembled poly(ethylene glycol)-poly(D,L-lactic acid) nanoparticles modified with PEI as gene delivery carrier, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.


Researcher : Man KCK

List of Research Outputs

CHUI S.L.C., Man K.C.K., Cheng C.L., Chan E.W., LAU C.Y., Cheng V.C.C., Wong D.S.H., Yan-Kao Y.E. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. , J Antimicrobial chemotherapy.. 2014.
Chui S.L.C., Man K.C.K., Cheng C.L., Chan E.W., Lau C.Y., Cheng V.C.C., Wong D.S.H., Yang-Kao Y.H. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: A self-controlled case series study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 151.
HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
HE Y., LAU C.Y., Chan E.W., Man K.C.K., Cheng V.C. and Wong I.C.K., High-Versus-Low-Dose Histamine-2 antagonists for the Prophylaxis of Non-Steroidal Anti-Inflammatory Drug-Associated Gastrointestinal Ulcers, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
He Y., Chan E.W., Cheng V.C.C., Lau C.Y., Man K.C.K. and Wong I.C.K., High-versus-low-dose histamine-2 antagonists for the prophylaxis of non-steroidal anti-inflammatory drug-associated gastrointestinal ulcers, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 170.
Iessa N., Murray M.L. and Man K.C.K., Leukotriene receptor antagonists and suicide: a self-controlled case series study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 141.
Leung P.S.C., Man K.C.K., Chui S.L.C., Chan E.W. and Tsui M.S.H., A retrospective study of medical staff manpower and service demand in a Hong Kong Accident and Emergency Department. , 15th International Conference on Emergency Medicine (ICEM 2014), 10-14 June 2014, Wan Chai Conference and Convention Centre. 2014.
Man K.C.K., Ip P., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W., Chow C., Yung A. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder Drug Prescribing Trend is Increasing Among Children and Adolescents in Hong Kong: 2001-2012, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
Man K.C.K., Chan E.W., Douglas I., Ip P., Wong W.H.S., Coghill D. and Wong I.C.K., Attention-Deficit/Hyperactivity disorder (ADHD) Pharmacological Treatment and its Effect on Accident and Emergency Admission due to injury: a self-controlled case series study., 3rd EUNETHYDIS, Istanbul, Turkey, 21-24 May . 2014.
Man K.C.K., P L.P., Hsia Y.F., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A. and Wong I.C.K., Attention-deficit/hyperactivity disorder drug prescribing trend is increasing among children and adolescents in Hong Kong, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 141.


Researcher : Man RYK

Project Title:Outstanding Research Student Supervisor Award 2007-2008
Investigator(s):Man RYK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Outstanding Research Student Supervisor Award
Start Date:10/2008


Project Title:Peroxisome Proliferator-Activated Receptors and Vascular Function
Investigator(s):Man RYK, Leung SWS, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2011


Project Title:Involvement of cyclooxygenase pathway in the vascular actions of estrogen
Investigator(s):Man RYK, Leung SWS
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2012
Completion Date:11/2013


Project Title:Potential protective effects of L-citrulline supplementation against endothelial dysfunction: role of arginase
Investigator(s):Man RYK, Leung SWS
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:03/2013
Completion Date:08/2014


Project Title:Vascular effects of 8-pCPT, an Epac activator
Investigator(s):Man RYK, Leung SWS
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

LI Z., Wang Y., Man R.Y.K. and Vanhoutte P.M.G.R., Upregulation of heme oxygenase-1 potentiates EDH-type relaxations in the mesenteric artery of the spontaneously hypertensive rat, Am J Physio Heart Circ. Physiol. 2013, 305: H1471-H1483.
LIU W.Y., Au Yeung K.W., Ko J.K.S., Man R.Y.K. and Leung S.W.S., Astragalus Membranaceus (Huangqi) exerts differential angiogenic properties under physiological and pathological conditions, 5th International Meeting on Angiogenesis, 12-14 March 2014, Amsterdam, The Netherlands. 2014.
LIU W.Y., Auyeung K.K.W., Ko J.K.S., Man R.Y.K. and Leung S.W.S., The effect of Astragalus Membranaceus on pathological angiogenesis, Seventeenth Annual Scientific meeting of the Institute of Cardiovascular Science and Medicine, “Translating Advances in Science into Improvements in Cardiovascular Health, 23 Nov 2013, Hong Kong. 2013.
Yeung D.K.Y., Pu Q., Man R.Y.K. and Leung S.W.S., Involvement of calcium.camodulin-dependent kinase II in the regulation of vascular tone in porcine coronary arteries, Seventeenth Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine “Translating advances in science into improvements in cardiovascular health”, 23 Nov 2013, Hong Kong. 2013.
ZHANG Y., Leung S.W.S. and Man R.Y.K., Anti-inflammatory effect of MIR-17-3P via NF-KB pathway in human endothelial cells, Seventeenth Annual Scientific Meeting, The Institute of Cardiovascular Science and Medicine, November 23, 2014, Hong Kong. 2013.
ZHANG Y., Leung S.W.S. and Man R.Y.K., Anti-inflammatory effect of miR-17-3p in human umbilical vein endothelial cells , Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
ZHANG Y., Leung S.W.S. and Man R.Y.K., Role of miR-17-3p in vascular inflammation, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.


Researcher : SONG E

List of Research Outputs

Liang Y., Huang B., Song E., Bai B. and Wang Y., Constitutive activation of AMPK α1 in vascular endothelium promotes high fat diet-induced fatty liver injury: role of cyclooxygenase-2 induction., British Journal of Pharmacology. 2014, 171: 498-508.
SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
SONG E., Fan P., Huang B., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice, J Am Heart Assoc.. 2014, 3: e000837.
SONG E., FAN P., Xu A., Feletou M., Vilaine J.P., Vanhoutte P.M.G.R. and Wang Y., Elevated 20-HETE contributes to the improved endothelial function in llpocalin-2 deficient mice, The 12th Meeting of the Asia Pacific Federation of Pharmacologists, Shanghai China, July 9-13, 2013.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.


Researcher : Shen K

List of Research Outputs

Shen K., Leung S.W.S., Huang Y., Hou M., Xu A., Wang Z. and Vanhoutte P.M.G.R., Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries, Biochem Pharmacol. 2014, Epub ahead of print.


Researcher : Sing CW

List of Research Outputs

Botzenhardt S., Sing C.W., Wong I.C.K. and Neubert A., Serious adverse drug events during deferiprone therapy in paediatric thalassaemia Patients, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 143.
Cheung C.L., Sahni S., Cheung B.M.Y., Sing C.W. and Wong I.C.K., Vitamin K intake reduces mortality in people with chronic kidney disease, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Hsu W.W.Q., Sing C.W., He Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy., CNS drugs. 2013.
Hsu W.W.Q., Sing C.W., HE Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy. , International Society of Pharmacovigilance XIII meeting, Pisa, October 1-4 International Society for Pharmacoepidemiology (ISPE) 8th Asian Conference on Pharmacoepidemiology; The University of Hong Kong, 25-27 October. 2013.


Researcher : Song E

List of Research Outputs

Liang Y., Huang B., Song E., Bai B. and Wang Y., Constitutive activation of AMPK α1 in vascular endothelium promotes high fat diet-induced fatty liver injury: role of cyclooxygenase-2 induction., British Journal of Pharmacology. 2014, 171: 498-508.
SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
SONG E., Fan P., Huang B., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice, J Am Heart Assoc.. 2014, 3: e000837.
SONG E., FAN P., Xu A., Feletou M., Vilaine J.P., Vanhoutte P.M.G.R. and Wang Y., Elevated 20-HETE contributes to the improved endothelial function in llpocalin-2 deficient mice, The 12th Meeting of the Asia Pacific Federation of Pharmacologists, Shanghai China, July 9-13, 2013.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.


Researcher : Tang EHC

Project Title:EP4 agonists alleviate inflammation in mouse models of atherosclerosis and obesity.
Investigator(s):Tang EHC, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012
Completion Date:04/2014


Project Title:Activation of prostaglandin E receptor 4: a novel anti-inflammatory mechanism that protects against adipose tissue inflammation and obesity-related complications.
Investigator(s):Tang EHC, Vanhoutte PMGR, Xu A
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:08/2012


Project Title:Regulation of triglyceride metabolism by prostaglandin E receptor subtype 4
Investigator(s):Tang EHC
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013


Project Title:Rap1 aggravates the development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice.
Investigator(s):Tang EHC
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Knockdown of Repressor Activator Protein 1 (Rap1) Suppresses NFKB-Dependent Inflammation in Human Macrophages, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Mice Lacking Prostaglandin E Receptor Subtype 4 Resist Diet-Induced Obesity Despite Hypertriglyceridemia, Arteriosclerosis, Thrombosis and Vascular Biology 2014, May 1-3, 2014, Toronto, Canada. 2014.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Role of prostaglandin E receptor subtype 4 (EP4) in the regulation of triglyceride metabolism, Seventeenth Annual Scientific Meeting, The Institute of Cardiovascular Science and Medicine, November 23, 2014, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Telomere-independent Rap1, modulates NF-kB-dependent inflammation in macrophages, 12th Meeting of the Asia Pacific Federation of Pharmacologists & Joint Meeting of Pharmacology of Chinese Pharmacological Society and Hong Kong Pharmacology Society, Shanghai, July 9-13, 2013. S11.3 (Acta Pharmacologica Sinica, Volume 34 Supplement, July 2013). 2013.
Rocha V.Z., Sheikine Y., Christen T., Folco E.J., Sukhova G., Tang E.H.C., Luster A. and Libby P., CXCR3 controls T cell accumulation in fat accumulation, Arterioscler Thromb Vasc Biol. 2014, 34: 1374-81.


Researcher : Tang HC

Project Title:EP4 agonists alleviate inflammation in mouse models of atherosclerosis and obesity.
Investigator(s):Tang EHC, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2012
Completion Date:04/2014


Project Title:Activation of prostaglandin E receptor 4: a novel anti-inflammatory mechanism that protects against adipose tissue inflammation and obesity-related complications.
Investigator(s):Tang EHC, Vanhoutte PMGR, Xu A
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:08/2012


Project Title:Regulation of triglyceride metabolism by prostaglandin E receptor subtype 4
Investigator(s):Tang EHC
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013


Project Title:Rap1 aggravates the development of angiotensin II-induced aortic abdominal aneurysm in apolipoprotein E-deficient mice.
Investigator(s):Tang EHC
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs



Researcher : Tom WM

Project Title:VII World Conference on Clinical Pharmacology and Therapeutics 4th Congress of the European Association for Clinical Pharmacology and Therapeutics Antidotal Mechanisms of Hydroxyacetone and Dihydroxyacetone in the Treatment of Acute Acetonitrile Poisoning
Investigator(s):Tom WM
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2000




Researcher : Tong HHY

List of Research Outputs

CHEN S., Tong H.H.Y. and Kwok P.C.L., Spray dried oleanolic acid powder for pulmonary delivery, The 5th Asian Arden Conference, Aichi Gakuin University, Nagoya, Japan, 5-6 August 2013.


Researcher : Vanhoutte P.M.G.

Project Title:Annual Summer School in Danish Cardiovascular Research Academy Veins in health and disease
Investigator(s):Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2007


Project Title:Visiting Research Professors Scheme 2009-10
Investigator(s):Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:Visiting Research Professors Scheme
Start Date:09/2009


Project Title:A Study of the Relative Significance of Nitric Oxide Synthase vs NADPH oxidase in Endothelial Senescence
Investigator(s):Vanhoutte PMGR, Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:10/2009


List of Research Outputs



Researcher : Vanhoutte PMGR

Project Title:Annual Summer School in Danish Cardiovascular Research Academy Veins in health and disease
Investigator(s):Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2007


Project Title:Visiting Research Professors Scheme 2009-10
Investigator(s):Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:Visiting Research Professors Scheme
Start Date:09/2009


Project Title:A Study of the Relative Significance of Nitric Oxide Synthase vs NADPH oxidase in Endothelial Senescence
Investigator(s):Vanhoutte PMGR, Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:10/2009


List of Research Outputs

Al-Daghri N.M., Khan N., Alkharfy K.M., Al-Attas O.S., Alokail M.S., Alfawaz H.A., Alothman A. and Vanhoutte P.M.G.R., Selected Dietary Nutrients and the Prevalence of Metabolic Syndrome in Adult Males and Females in Saudi Arabia: A Pilot Study, Nutrients. 2013, 5: 4587-4604.
Alokail M.S., Sabico S., Al-Saleh Y., Al-Daghri N.M., Alkharfy K.M., Vanhoutte P.M.G.R. and McTernan P.G., Effects of probiotics in patients with diabetes mellitus type 2: study protocol for a randomized, double-blind, placebo-controlled trial, TRIALS. 2013, 14: 195.
BARETELLA O.M., Xu A. and Vanhoutte P.M.G.R., Acidosis prevents and alkalosis augments endothelium-dependent contractions in mouse arteries, Pflugers Archiv : European journal of physiology. . 2013, Epub [2013 Jul 20].
BARETELLA O.M., Chung S.K., Barton M., Xu A. and Vanhoutte P.M.G.R., Obesity and heterozygous endothelial overexpression of prepro-endothelin-1 modulate responsiveness of mouse main and segmental renal arteries to vasoconstrictor agents., Life Sci. . 2014, Epub ahead of print.
Bai B., Liang Y., Xu C., Lee Y.K.M., Xu A., Wu D.H., Vanhoutte P.M.G.R. and Wang Y., CDK5-mediated hyperphosphorylation contributes to the lossof-SIRT1 function during the development of endothelial senescence, International Academy of Cardiology: 18th World congress on Heart Disease, Vancouver, Canada, July 26-29, 2013.
Bai B., Vanhoutte P.M.G.R. and Wang Y., Loss-of-SIRT1 function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5. , Trends in Cardiovascular Medicine . 2013.
Baretella O.M., Xu A. and Vanhoutte P.M.G.R., Contractions to endogenous and exogenous endothelin-1 in segmental renal arteries of the mouse: up-regulation in obesity, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Heterozygous Endothelial Endothelin-1 Overexpression Potentiates Endothelium-Dependent Contractions in the Carotid Arteries of Obese Mice, HBPR 2013, September 11-14, 2013, New Orleans, LA. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Heterozygous overexpression of preproendothelin-1 in endothelial cells enhances thromboxane-prostanoid receptor-induced contractions in the renal artery of obese mice, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
Baretella O.M., Chung S.K., Xu A. and Vanhoutte P.M.G.R., Improved relaxations to acetylcholine in murine carotid arteries with heterozygous overexpression of preproendothelin-1 in the endothelium, 13th International Conference on Endothelin, September 8-11, 2013, University of Tsukuba, Tokyo. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Knockdown of Repressor Activator Protein 1 (Rap1) Suppresses NFKB-Dependent Inflammation in Human Macrophages, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Mice Lacking Prostaglandin E Receptor Subtype 4 Resist Diet-Induced Obesity Despite Hypertriglyceridemia, Arteriosclerosis, Thrombosis and Vascular Biology 2014, May 1-3, 2014, Toronto, Canada. 2014.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Role of prostaglandin E receptor subtype 4 (EP4) in the regulation of triglyceride metabolism, Seventeenth Annual Scientific Meeting, The Institute of Cardiovascular Science and Medicine, November 23, 2014, Hong Kong. 2013.
CAI Y., Vanhoutte P.M.G.R. and Tang E.H.C., Telomere-independent Rap1, modulates NF-kB-dependent inflammation in macrophages, 12th Meeting of the Asia Pacific Federation of Pharmacologists & Joint Meeting of Pharmacology of Chinese Pharmacological Society and Hong Kong Pharmacology Society, Shanghai, July 9-13, 2013. S11.3 (Acta Pharmacologica Sinica, Volume 34 Supplement, July 2013). 2013.
Chan K.Y.C., Liao S., Zhang Y., Xu A., Tse H.F. and Vanhoutte P.M.G.R., Protective effects of histamine on Gq-mediated relaxation in regenerated endothelium, Am J Physiol Heart Circ Physiol. 2014, 306: H286-90.
DETREMMERIE C.M.S., Leung S.W.S., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., The endothelium-dependent, soluble guanylyl cyclase-dependent augmentation caused by thymoquinone in isolated porcine coronary arteries is mediated by cIMP, Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
DETREMMERIE C.M.S., Leung S.W.S., Xu A., Alkharfy K. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation depending on activation of soluble guanylyl cyclase in isolated arteries, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.
De Mey J.G.R. and Vanhoutte P.M.G.R., End O' The Line Revised: Moving on from nitric oxide to CGRP, Life Sciences. 2014.
Eskildsen M.P., Hansen P.B.L., Stubbe J., Toft A., Walter S., Marcussen N., Rasmussen L.M., Vanhoutte P.M.G.R. and Jensen B.L., Prostaglandin I2 and Prostaglandin E2 Modulate Human Intrarenal Artery Contractility Through Prostaglandin E2-EP4, Prostacyclin-IP, and Thromboxane A2-TP Receptors., Hypertension. 2014, 64: 551-556.
Hui X., Gu P., Lam K.S.L., Vanhoutte P.M.G.R. and Xu A., SIRT1 modulates white/brown switch in PVAT, 8th Singapore Diabetes Forum. 2014.
LI H., MAO X., Irwin M.G., Wong G.T.C., Clananchan A.S., Vanhoutte P.M.G.R. and Xia Z., PROPOFOL CONFERS CARDIOPROTECTION VIA HO-1 DEPENDENT STAT3 ACTIVATION IN NORMAL RATS BUT VIA ADIPONECTIN DEPENDENT STAT3 ACTIVATION IN TYPE 1 DIABETIC RATS, Anesth Analg: International Anesthesia Research Society (IARS) annual meeting 2014. 118: S-1 – S-319.
LI H., MAO X., Irwin M.G., Wong G.T.C., Clananchan A.S., Vanhoutte P.M.G.R. and Xia Z., Resident Abstract Award Finalist: "Propofol Confers Cardioprotection via HO-1 Dependent STAT3 Activation in Normal Rats but via Adiponectin Dependent STAT3 Activation in Type 1 Diabetic Rats", International Anesthesia Research Society (IARS) (ANESTH ANALG ). 2014, 118: S-1 – S-319.
LI Z., Wang Y., Man R.Y.K. and Vanhoutte P.M.G.R., Upregulation of heme oxygenase-1 potentiates EDH-type relaxations in the mesenteric artery of the spontaneously hypertensive rat, Am J Physio Heart Circ. Physiol. 2013, 305: H1471-H1483.
Leung S.W.S., DETREMMERIE C.M.S., LI Z., Xu A., Alkharfy K., Gao Y. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent augmentation of contraction depending on activation of soluble guanylyl cyclase in isolated arteries, 11th International Symposium on Mechanisms of Vasodilatation, 3 to 7 Oct 2013, Zurich, Switzerland. 2013.
Leung S.W.S., LI Z., Alkharfy K. and Vanhoutte P.M.G.R., Thymoquinone causes endothelium-dependent contractions depending on activation of soluble guanylyl cyclase in isolated rat arteries, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China. 2013.
MAO X., Wang T., LIU Y., Irwin M.G., Ou J., Liao X.L., Gao X., Xu Y., Ng J.K.F., Vanhoutte P.M.G.R. and Xia Z., N-Acetylcysteine and Allopurinol Confer Synergy in Attenuating Myocardial Ischemia Injury via Restoring HIF-1α/HO-1 Signaling in Diabetic Rats, PLoS ONE. 2013, 8(7):e68949.: e68949.
Mokhtar S.S., Vanhoutte P.M.G.R., Leung S.W.S., Yusoi M.I., Sulaiman W.A.W., Saad A.Z.M., Suppian R. and Rasool A.H.G., Reduced expression of prostacyclin synthase and nitric oxide synthase in subcutaneous arteries of Type 2 diabetic patients, The Tohoku Journal of Experimental Medicine. 2013, 231: 217-222.
Raffai G., Kim B., Park S., Khang G., Lee D. and Vanhoutte P.M.G.R., Cinnamaldehyde and cinnamaldehyde-containing micelles induce relaxation of isolated porcine coronary arteries: role of nitric oxide and calcium, International Journal of Nanomedicine. 2014, 9: 1-10.
SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
SONG E., Fan P., Huang B., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice, J Am Heart Assoc.. 2014, 3: e000837.
SONG E., FAN P., Xu A., Feletou M., Vilaine J.P., Vanhoutte P.M.G.R. and Wang Y., Elevated 20-HETE contributes to the improved endothelial function in llpocalin-2 deficient mice, The 12th Meeting of the Asia Pacific Federation of Pharmacologists, Shanghai China, July 9-13, 2013.
Shen K., Leung S.W.S., Huang Y., Hou M., Xu A., Wang Z. and Vanhoutte P.M.G.R., Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries, Biochem Pharmacol. 2014, Epub ahead of print.
Shi Y. and Vanhoutte P.M.G.R., Reactive Oxygen Species and Endothelium-Derived Contracting Factor (EDCF) – Partners in Endothelial Dysfunction, Systems Biology of Free Radicals and Antioxidants. 2014, 2014: 1325-1342.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.
Vanhoutte P.M.G.R., The Endothelial saga: From Function to Dysfunction, The 87th Annual Meeting of The Japanese Pharmacological Society, March 19-21, 2014, Sendai, Japan. 2014.
Wang P., Xu T.Y., Guan Y.F., Zhao Y., Li Z.Y., Lan X.H., Wang X., Yang P.Y., Kang Z.M., Vanhoutte P.M.G.R. and Miao C.Y., Vascular smooth muscle cell apoptosis is an early trigger for hypothyroid atherosclerosis, Cardiovascular Research. 2014, 102: 448-459.
Wang Y. and Vanhoutte P.M.G.R., Targeting Endothelial Senescence for Atherosclerosis Treatment: an Approach Based on SIRT1 Modification , IAS (International Atherosclerosis Society). 2013.
Xu C., Fan P., Xu A., Vanhoutte P.M.G.R. and Wang Y., Biotin deficiency mimics the beneficial effects of calorie restriction by regulating SIRT1 and acetyl-coA carboxylase 2 in the adipose tissues, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
YEUNG Y.T., LEE S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Prolonged exposure to lopinavir impairs endothelium-dependent hyperpolarization-mediated relaxation in rat mesenteric arteries, Journal of Cardiovascular Pharmacology. 2013, 62: 397-404.
ZHAO Y., Leung S.W.S. and Vanhoutte P.M.G.R., Activation of α1-adrenergic receptors causes thromboxane-prostanoid receptor desensitization in the aorta of the spontaneously hypertensive rat, Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
ZOU Q., Leung S.W.S. and Vanhoutte P.M.G.R., Endogenous acetylcholine contributes to mild hypothermia induced endothelium-dependent relaxations in the SHR aorta, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.


Researcher : WONG YS

List of Research Outputs

HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
Hsia Y., WONG Y.S., Murphy D.G., Simonoff E., Buitelaar J.K. and Wong I.C.K., Psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study., Psychopharmacology . 2013, 231: 999-1009.
WONG Y.S., Hsia Y.F., Chan E.W., Murphy D.G.M., Simonoff E., Buitelaar J.K. and Wong I.C.K., The Variation of Psychopharmacological Prescription Rates for People With Autism Spectrum Disorder (ASD) in 30 Countries, Autism Research. 2014, n/a-n/a.
WONG Y.S., Chan E.W., CHUI S.L.C., SUTCLIFFE A.G. and Wong I.C.K., The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature., Public Health Nutrition. 2013, 17(11): 2605-2618.
Wong Y.S., Hsia Y.F., Chan E.W. and Wong I.C.K., The variation of psychopharmacological treatment for people with autistic spectrum disorder (ASD): an international study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 160.


Researcher : Wang Y

Project Title:Protective effect of lipocalin-2 deficiency on aging- and dietary obesity-induced endothelial dysfunction
Investigator(s):Wang Y, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2010
Completion Date:09/2013


Project Title:Outstanding Young Researcher Award 2009-10
Investigator(s):Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Outstanding Young Researcher Award
Start Date:12/2010


Project Title:Vascular protective functions of the anti-aging protein SIRT1 by targeting LKB1/AMPK pathway in endothelial cells: tipping the balance towards vascular homeostasis
Investigator(s):Wang Y, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2011


Project Title:Role of adipose SIRT1 in regulating systemic energy homeostasis and vascular function: focus on biotin, biotinyl enzymes and lipid metabolism
Investigator(s):Wang Y, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2012


Project Title:HERC2 in regulating endothelial senescence and vascular homeostasis
Investigator(s):Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013
Completion Date:05/2014


Project Title:HERC2 as a regulator of endothelial senescence by modulating SIRT1/LKB1 signaling axis
Investigator(s):Wang Y, Tse HF
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Activation of lipocalin-2 by deamidation in peri-vascular adipose tissues
Investigator(s):Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Bai B., Liang Y., Xu C., Lee Y.K.M., Xu A., Wu D.H., Vanhoutte P.M.G.R. and Wang Y., CDK5-mediated hyperphosphorylation contributes to the lossof-SIRT1 function during the development of endothelial senescence, International Academy of Cardiology: 18th World congress on Heart Disease, Vancouver, Canada, July 26-29, 2013.
Bai B., Vanhoutte P.M.G.R. and Wang Y., Loss-of-SIRT1 function during vascular ageing: hyperphosphorylation mediated by cyclin-dependent kinase 5. , Trends in Cardiovascular Medicine . 2013.
CAI Y. and Wang Y., Modulation of SIRT1 activity in adipose tissue affects mitochondrial function, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
CHEN J., Xu A., Lam K.S.L., Liu J. and Wang Y., Adiponectin deficiency promotes the development of metaplastic breast cancer-focusing on dysregulated T-cell function, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
CHEN J. and Wang Y., Metaplastic breast cancer – a rare but challenging entity. , Trends in Cancer Research. 2013, 9: 65-71.
Che C.M., Sun R.W.Y., Wang Y. and Chow K.H., Treating cancer (e.g. cervical epithelioid carcinoma, hepatocellular carcinoma, breast carcinoma and/or lung carcinoma) comprises administering composition comprising new or known substituted gold(III) porphyrin complexes, European Patent Office. 2014, EP2493897-B1.
Cheng K.Y., Zhu W., CHEN B., Wang Y., Wu D., Sweeney G., WANG B., Lam K.S.L. and Xu A., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle, Diabetes. 2014, DB_140337: Epub ahead of print.
Cheng K.Y., Lam K.S.L., Wang Y., Wu D., Zhang M., WANG B., Li X., Hoo R.L.C., HUANG Z., Sweeney G. and Xu A., Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of akt, Biochem J. 2013, Epub [2013 Aug 5].
LI Z., Wang Y., Man R.Y.K. and Vanhoutte P.M.G.R., Upregulation of heme oxygenase-1 potentiates EDH-type relaxations in the mesenteric artery of the spontaneously hypertensive rat, Am J Physio Heart Circ. Physiol. 2013, 305: H1471-H1483.
Li H., Hui X., Yang S., Hu X., Tang X., Li P., Li S., Yang L., Jin S., Wang Y., Xu A. and Wu D., High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pichia pastoris, Protein Expr Purif. 2013, 91: 221-227.
Li H., Hui X., Yang S., Hu X., Tang X., Li P., Li S., Yang L., Jin S. and Wang Y., High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pichia pastoris, Protein Expression and Purification. 2013, 91: 221-227.
Liang Y., Huang B., Song E., Bai B. and Wang Y., Constitutive activation of AMPK α1 in vascular endothelium promotes high fat diet-induced fatty liver injury: role of cyclooxygenase-2 induction., British Journal of Pharmacology. 2014, 171: 498-508.
Lin Z., Wu F., Lin S., Pan X., Jin L., Lu T., Shi L., Wang Y., Xu A. and Li X., Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice. , Journal of Hepatology. 2014, Epub ahead of print.
Lin Z., Wu F., Lin S., Pan X., Jin L., Lu T., Wang Y., Xu A. and Li X., Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice, J Hepatol.. 2014, pii: S0168-8278: [Epub ahead of print].
Liu J., Xu A., Lam K.S.L., Wong N.S., CHEN J., Shepherd P.R. and Wang Y., Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation, Oncotarget . 2013, 4: 1804-18.
SONG E., Fan P., Huang B., Deng H., Feletou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin-2 Induces Endothelial Dysfunction in Dietary Obese Mice, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.
SONG E., Fan P., Huang B., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction and hypertension in dietary obese mice, J Am Heart Assoc.. 2014, 3: e000837.
SONG E., FAN P., Xu A., Feletou M., Vilaine J.P., Vanhoutte P.M.G.R. and Wang Y., Elevated 20-HETE contributes to the improved endothelial function in llpocalin-2 deficient mice, The 12th Meeting of the Asia Pacific Federation of Pharmacologists, Shanghai China, July 9-13, 2013.
Shiu S.W.M., Xiao S., Wang Y., Chow W.S., Lam K.S.L. and Cheung B.M.Y., Carbamylation of LDL and its relationship with myeloperoxidase in type 2 diabetes mellitus, Clin Sci (Lond). 2014, 126: 175-81.
Song E., Fan P., Huang B., Deng H., Cheung B.M.Y., Félétou M., Vilaine J.P., Villeneuve N., Xu A., Vanhoutte P.M.G.R. and Wang Y., Deamidated Lipocalin‐2 Induces Endothelial Dysfunction and Hypertension in Dietary Obese Mice, Journal of America Heart Association. 2014, 3.
Wang Y., Adipokines as biomarkers and drug targets for obesity-related cardiometabolic diseases. , 2013 AAPS@China Symposium. 2013.
Wang Y., Calorie restriction prevents adipose SIRT1 dysfunction-induced metabolic ageing., 2014 Seoul International Congress of Endocrinology and Metabolism & Asia-Pacific Diabetes and Obesity Study Group. 2014.
Wang Y., Deamidated lipocalin-2 induces endothelial dysfunction in dietary obese mice. , 2014 Osaka Symposium on Obesity and Diabetes. 2014.
Wang Y., Lipocalin-2 activation by deamidation causes endothelial dysfunction and hypertension in obese mice. , Danish Cardiovascular Research Academy 2014 Summer Meeting. 2014.
Wang Y., Modulation of SIRT1 Activity in Adipose Tissue: Biotin versus Caloric Restriction, 5th Singapore Symposium on Metabolic Diseases. 2013.
Wang Y., Modulation of SIRT1 activity in adipose tissue – biotin versus caloric restriction., 2013 Summer Symposium by Vascular Cell Research Council in Korean Diabetes Association. 2013.
Wang Y. and Vanhoutte P.M.G.R., Targeting Endothelial Senescence for Atherosclerosis Treatment: an Approach Based on SIRT1 Modification , IAS (International Atherosclerosis Society). 2013.
Wang Y., Targeting endothelial senescence for atherosclerosis treatment: an approach based on SIRT1 modification. , International Conference on Diabetes and Metabolism (ICDM) & the 5th Scientific Meeting of Asian Association for the Study of Diabetes (AASD). 2013.
Wang Y., The vascular protective functions of SIRT1. , 2013 Young-Honam Endocrinology and Metabolism Meeting. 2013.
Wong S.S.W., Kao R.Y.T., Yuen K.Y., Wang Y., Yang D., Samaranayake L.P. and Seneviratne C.J., In vitro and In vivo activity of a novel antifungal small molecule against Candida infections, PloS one. 2014, 9(1): e85836.
Xu C., Fan P., Xu A., Vanhoutte P.M.G.R. and Wang Y., Biotin deficiency mimics the beneficial effects of calorie restriction by regulating SIRT1 and acetyl-coA carboxylase 2 in the adipose tissues, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.
Yang S., Kuang Y., Li H., Liu Y., Hui X., Li P., Jiang Z., Zhou Y., Wang Y., Xu A., Li S., Liu P. and Wu D., Enhanced production of recombinant secretory proteins in Pichia pastoris by optimizing Kex2 P1' site., Plos One. 2013, 8: e75347.
Ye D., Wang Y., Li H., Jia W., Man K., Lo C.M., Wang Y., Lam K.S.L. and Xu A., Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice, Hepatology. 2014, Epub on 2014-02-06.
Yeung C.Y., Tso A.W.K., Xu A., Wang Y., Woo Y.C., Lam T.H., Lo S.V., Fong H.Y., Wat N.M.S., Woo J., Cheung B.M.Y. and Lam K.S.L., Pro-inflammatory adipokines as predictors of incident cancers in a Chinese cohort of low obesity prevalence in Hong Kong, PLoS One . 2013, 8: e78594.


Researcher : Wang Y.

Project Title:Protective effect of lipocalin-2 deficiency on aging- and dietary obesity-induced endothelial dysfunction
Investigator(s):Wang Y, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2010
Completion Date:09/2013


Project Title:Outstanding Young Researcher Award 2009-10
Investigator(s):Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Outstanding Young Researcher Award
Start Date:12/2010


Project Title:Vascular protective functions of the anti-aging protein SIRT1 by targeting LKB1/AMPK pathway in endothelial cells: tipping the balance towards vascular homeostasis
Investigator(s):Wang Y, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2011


Project Title:Role of adipose SIRT1 in regulating systemic energy homeostasis and vascular function: focus on biotin, biotinyl enzymes and lipid metabolism
Investigator(s):Wang Y, Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2012


Project Title:HERC2 in regulating endothelial senescence and vascular homeostasis
Investigator(s):Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013
Completion Date:05/2014


Project Title:HERC2 as a regulator of endothelial senescence by modulating SIRT1/LKB1 signaling axis
Investigator(s):Wang Y, Tse HF
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Activation of lipocalin-2 by deamidation in peri-vascular adipose tissues
Investigator(s):Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs



Researcher : Wong ICK

Project Title:Oral Transmucosal Drug Delivery System for Paediatric and Emergency Medications.
Investigator(s):Wong ICK, Lam JKW, Kwok PCL
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2012
Completion Date:02/2014


Project Title:‘’The Renaissance of Pharmacovigilance“; Medication-related problems in children/Reporting and analyzing medication errors, abuses and misuses
Investigator(s):Wong ICK
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2013
Completion Date:10/2013


Project Title:Effects of Attention Deficit Hyperactivity Disorder (ADHD) pharmacotherapy on hospital accident and emergency admission due to injury-related events. Acronym: ATHAN (ADHD Treatments and Hospital Accident and emergency admission aNalysis)
Investigator(s):Wong ICK, Ip P, Wong WHS
Department:Pharmacology & Pharmacy
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2013


Project Title:The association between oral fluoroquinolones and incident seizure event
Investigator(s):Wong ICK, Chan EW
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:05/2014


Project Title:Mother’s preferences and willingness to pay for human papillomavirus vaccination for their daughters: a discrete choice experiment in Hong Kong
Investigator(s):Wong ICK, McGhee S, Tse VC, Wong CKH, Ip DKM, Chau J
Department:Pharmacology & Pharmacy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2014


List of Research Outputs

Almandil N.B., Ohlsen R., Murray M.L., Besag F.M.C., Aitchison K.J. and Wong I.C.K., Pharmacogenetics of weight gain in young people treated with Risperidone, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 142.
Botzenhardt S., Sing C.W., Wong I.C.K. and Neubert A., Serious adverse drug events during deferiprone therapy in paediatric thalassaemia Patients, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 143.
CHUI S.L.C., Man K.C.K., Cheng C.L., Chan E.W., LAU C.Y., Cheng V.C.C., Wong D.S.H., Yan-Kao Y.E. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: a self-controlled case series study. , J Antimicrobial chemotherapy.. 2014.
Chan E.W., Leung L.P., Tsui M.S.H., Ho H.K., Wong C.K., Kong D.C.M., Taylor D.M.C.D., Knott J.C. and Wong I.C.K., Management of acute agitation in the Accident and Emergency setting: A survey of practice in Hong Kong. , 15th International Conference on Emergency Medicine (ICEM 2014), 10-14 June 2014, Wan Chai Conference and Convention Centre. 2014.
Cheung C.L., Sahni S., Cheung B.M.Y., Sing C.W. and Wong I.C.K., Vitamin K intake reduces mortality in people with chronic kidney disease, 19th Medical Research Conference. Hong Kong Medical Journal. 2014, 16.
Christie D., Thompson R., Sawtell M., Allen E., Cairns J., Smith F., Jamieson E., Hargreaves K., Ingold A., Brooks L., Wiggins M., Oliver S., Jones R., Elbourne D., Santos A., Wong I.C.K., O'Neill S., Strange V., Hindmarsh P., Annan F. and Viner R., Structured intensive education maximising engagement, motivation and long term change for children and young people with diabetes: cluster randomised controlled trial with integral process and economic evaluation: The CASCADE study, Health Technol Assess Journal. 2014, 18(20).
Chui S.L.C., Man K.C.K., Cheng C.L., Chan E.W., Lau C.Y., Cheng V.C.C., Wong D.S.H., Yang-Kao Y.H. and Wong I.C.K., An investigation of the association between retinal detachment and oral fluoroquinolones: A self-controlled case series study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 151.
Glennon J., Purper-Ouakil D., Bakker M., Zuddas A., Hoekstra P., Schulze U., Castro-Fornieles J., Santosh P.J., Arango C., Kölch M., Coghill D., Flamarique I., Penzol M.J., Wan M., Murray M., Wong I.C.K., Danckaerts M., Bonnot O., Falissard B., Masi G., Fegert J.M., Vicari S., Carucci S., Dittmann R.W., Buitelaar J.K. and The PERS C.O.N.S.O.R.T.I.U.M., The PERS Consortium. Paediatric European Risperidone Studies (PERS): context, rationale, objectives, strategy, and challenges.[Epub ahead of print], Eur Child Adolesc Psychiatry. 2013.
HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
HE Y., LAU C.Y., Chan E.W., Man K.C.K., Cheng V.C. and Wong I.C.K., High-Versus-Low-Dose Histamine-2 antagonists for the Prophylaxis of Non-Steroidal Anti-Inflammatory Drug-Associated Gastrointestinal Ulcers, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
He Y., Chan E.W., Cheng V.C.C., Lau C.Y., Man K.C.K. and Wong I.C.K., High-versus-low-dose histamine-2 antagonists for the prophylaxis of non-steroidal anti-inflammatory drug-associated gastrointestinal ulcers, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 170.
Hsia Y., Neubert A., Viner R. and Wong I.C.K., Anti-obesity drug prescribing in children and adolescents: a population-based study in the UK, Hong Kong Pharmaceutical Journal, 8th Asian Conference on Pharmacoepidemiology, October 25-27, 2013, Hong Kong. 2013, 20(3): 133.
Hsia Y., WONG Y.S., Murphy D.G., Simonoff E., Buitelaar J.K. and Wong I.C.K., Psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study., Psychopharmacology . 2013, 231: 999-1009.
Hsu W.W.Q., Sing C.W., He Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy., CNS drugs. 2013.
Hsu W.W.Q., Sing C.W., HE Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy. , International Society of Pharmacovigilance XIII meeting, Pisa, October 1-4 International Society for Pharmacoepidemiology (ISPE) 8th Asian Conference on Pharmacoepidemiology; The University of Hong Kong, 25-27 October. 2013.
Ibrahim N., Tomlin S., Sinha M.D., Wong I.C.K., Rees L. and Jani Y., Risk factors associated with drug-related problems in hospitalized paediatric nephrology patients, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 143.
Lam J.K.W., Xu Y., Worsley A.J. and Wong I.C.K., Oral Transmucosal Drug Delivery for Paediatric Use. , Adv Drug Deliv Rev.. 2013, 73: 50-62.
Leung A.Y.M., Wong I.C.K., Chen J.Y. and Lou V.W., Would dementia literacy play a role in positive caregiving in dementia., 16th Asia Pacific Regional Conference of Alzheimer’s Disease International, Hong Kong,. 2013.
Man K.C.K., Ip P., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W., Chow C., Yung A. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder Drug Prescribing Trend is Increasing Among Children and Adolescents in Hong Kong: 2001-2012, 13th ISOP Annual Meeting PISA Oct 1-4, 2013.
Man K.C.K., Chan E.W., Douglas I., Ip P., Wong W.H.S., Coghill D. and Wong I.C.K., Attention-Deficit/Hyperactivity disorder (ADHD) Pharmacological Treatment and its Effect on Accident and Emergency Admission due to injury: a self-controlled case series study., 3rd EUNETHYDIS, Istanbul, Turkey, 21-24 May . 2014.
Man K.C.K., P L.P., Hsia Y.F., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A. and Wong I.C.K., Attention-deficit/hyperactivity disorder drug prescribing trend is increasing among children and adolescents in Hong Kong, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 141.
Murray M.L., Hsia Y.F., El-Turki A., Sharland M., Saxena S., Long P. and Wong I.C.K., Impact of Pneumococcal Conjugate Vaccines (PCV) on the incidence of community acquired pneumonia (CAP) in the UK, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 149.
Murray M.L., Hsia Y.F., Glaser K., Simonoff E., Murphy D.G.M., Asherson P.J., Eklund H. and Wong I.C.K., Pharmacological treatments prescribed to young people with autism spectrum disorder (ASD) in UK primary care, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 142.
Rashed A.N., Wilton L., Tomlin S., Wong I.C.K. and Neubert A., Drug utilization patterns in hospitalized children: An international perspective, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 140.
Rashed A.N., Wilton L., Lo C.C.H., Kwong B.Y.S., Leung S. and Wong I.C.K., Epidemiology and potential risk factors of drug-related problems in Hong Kong Paediatric wards., British Journal of Clinical Pharmacology. 2013, 77(5): 873-9.
Saxena S., Ismael Z., Murray M.L., Barker C., Wong I.C.K., Sharland M. and Long P.F., Oral penicillin prescribing for children in the UK: a comparison with BNF for Children age-band recommendations., British Journal of General Practice. 2014, 64(621): e217-22.
Stevenson J., Buitelaar J., Cortese S., Ferrin M., Konofal E., Lecendreux M., Simonoff E., Wong I.C.K. and Sonuga-Barke E., Research Review: The role of diet in the treatment of attention-deficit/hyperactivity disorder - an appraisal of the evidence on efficacy and recommendations on the design of future studies, Journal child Psychology Psychiatry. 2014, 55(5): 416-427.
WONG Y.S., Hsia Y.F., Chan E.W., Murphy D.G.M., Simonoff E., Buitelaar J.K. and Wong I.C.K., The Variation of Psychopharmacological Prescription Rates for People With Autism Spectrum Disorder (ASD) in 30 Countries, Autism Research. 2014, n/a-n/a.
WONG Y.S., Chan E.W., CHUI S.L.C., SUTCLIFFE A.G. and Wong I.C.K., The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature., Public Health Nutrition. 2013, 17(11): 2605-2618.
Wahab M., Sutcliffe A., Wong I.C.K. and Jani Y., Complementary and alternative medicine use in the first trimester: safety perceptions and preference of pregnant women, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong. 2013, 20(3): 138.
Wong I.C.K., Antibiotic stewardship in Hong Kong, Medicines in Health: Shaping Our Future, Brisbane, 21-23 May 2014.
Wong I.C.K., Executive Editor , British Journal of Clinical Pharmacology. 2013.
Wong Y.S., Hsia Y.F., Chan E.W. and Wong I.C.K., The variation of psychopharmacological treatment for people with autistic spectrum disorder (ASD): an international study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 160.


Researcher : Wong KC

List of Research Outputs

Chan W.L.P., Chu K.P.J. and Wong K.C., Introduction to Problem-based Learning, China Pharmaceutical University. 中國藥科大學, 2014.


Researcher : Wong YS

List of Research Outputs

HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
Hsia Y., WONG Y.S., Murphy D.G., Simonoff E., Buitelaar J.K. and Wong I.C.K., Psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study., Psychopharmacology . 2013, 231: 999-1009.
WONG Y.S., Hsia Y.F., Chan E.W., Murphy D.G.M., Simonoff E., Buitelaar J.K. and Wong I.C.K., The Variation of Psychopharmacological Prescription Rates for People With Autism Spectrum Disorder (ASD) in 30 Countries, Autism Research. 2014, n/a-n/a.
WONG Y.S., Chan E.W., CHUI S.L.C., SUTCLIFFE A.G. and Wong I.C.K., The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature., Public Health Nutrition. 2013, 17(11): 2605-2618.
Wong Y.S., Hsia Y.F., Chan E.W. and Wong I.C.K., The variation of psychopharmacological treatment for people with autistic spectrum disorder (ASD): an international study, Hong Kong Pharmaceutical Journal: 8th Asian Conference on Pharmacoepidemiology, October 25 - 27, 2013, Hong Kong . 2013, 20(3): 160.


Researcher : Woo WHC

Project Title:Role of Toll-like Receptor in Obesity-induced Non-Alcohol Fatty Liver Disease
Investigator(s):Woo WHC, Xu A
Department:Pharmacology & Pharmacy
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:02/2014




Researcher : Worsley AJ

Project Title:The quantification and elucidation of alkaloid content of Strychnos angustiflora Benth Seeds and pericarp
Investigator(s):Worsley AJ, Dufay S
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:06/2014


List of Research Outputs

Dufay S. and Worsley A.J., Comparison of Biosimilar Guidelines: Impact on Patient Safety, International Society of Pharmacovigilance. 2013.
Dufay S. and Worsley A.J., Reduction of toxicity of Traditional Chinese Medicine Aconite in the domestic setting., International Society of Pharmacovigilance. 2013.
HE Y., WONG Y.S., Chan E.W., LAU C.Y., Man K.C.K., CHUI S.L.C., Worsley A.J. and Wong I.C.K., Efficacy and safety of tofacitinib in the treatment of rheumatoid arthritis: a systematic review and meta-analysis, BMC Musculoskeletal Disorders. 2013, 14: 298.
Hsu W.W.Q., Sing C.W., He Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Efficacy and Safety of Perampanel in the Treatment of Partial-Onset Epilepsy., CNS drugs. 2013.
Hsu W.W.Q., Sing C.W., HE Y., Worsley A.J., Wong I.C.K. and Chan E.W., Systematic Review and Meta-Analysis of the Safety of Perampanel in the Treatment of Partial-onset Epilepsy. , International Society of Pharmacovigilance XIII meeting, Pisa, October 1-4 International Society for Pharmacoepidemiology (ISPE) 8th Asian Conference on Pharmacoepidemiology; The University of Hong Kong, 25-27 October. 2013.
Lam J.K.W., Xu Y., Worsley A.J. and Wong I.C.K., Oral Transmucosal Drug Delivery for Paediatric Use. , Adv Drug Deliv Rev.. 2013, 73: 50-62.


Researcher : XU Y

List of Research Outputs

Lam J.K.W., Xu Y., Worsley A.J. and Wong I.C.K., Oral Transmucosal Drug Delivery for Paediatric Use. , Adv Drug Deliv Rev.. 2013, 73: 50-62.
XU Y., YE Y. and Lam J.K.W., Reversible permeability enhancement of DNA-loaded chitosan oligosaccharide nanoparticle across Calu-3 epithelial cell model for airway gene delivery, 40th Annual Meeting & Exposition of the Controlled Release Society, 21-24 July 2013. Hawaii, USA. 2013.


Researcher : Xu C

List of Research Outputs

Bai B., Liang Y., Xu C., Lee Y.K.M., Xu A., Wu D.H., Vanhoutte P.M.G.R. and Wang Y., CDK5-mediated hyperphosphorylation contributes to the lossof-SIRT1 function during the development of endothelial senescence, International Academy of Cardiology: 18th World congress on Heart Disease, Vancouver, Canada, July 26-29, 2013.
Xu C., Fan P., Xu A., Vanhoutte P.M.G.R. and Wang Y., Biotin deficiency mimics the beneficial effects of calorie restriction by regulating SIRT1 and acetyl-coA carboxylase 2 in the adipose tissues, Ninth International Symposium on Healthy Aging, March 8-9, 2014, Hong Kong. 2014.


Researcher : Xu Y

List of Research Outputs

Lam J.K.W., Xu Y., Worsley A.J. and Wong I.C.K., Oral Transmucosal Drug Delivery for Paediatric Use. , Adv Drug Deliv Rev.. 2013, 73: 50-62.
XU Y., YE Y. and Lam J.K.W., Reversible permeability enhancement of DNA-loaded chitosan oligosaccharide nanoparticle across Calu-3 epithelial cell model for airway gene delivery, 40th Annual Meeting & Exposition of the Controlled Release Society, 21-24 July 2013. Hawaii, USA. 2013.


Researcher : YEUNG YT

List of Research Outputs

YEUNG Y.T., LEE S.S., Vanhoutte P.M.G.R. and Leung S.W.S., Prolonged exposure to lopinavir impairs endothelium-dependent hyperpolarization-mediated relaxation in rat mesenteric arteries, Journal of Cardiovascular Pharmacology. 2013, 62: 397-404.


Researcher : Ye D

Project Title:Role of lipocalin-2 in nonalcoholic fatty liver disease
Investigator(s):Ye D, Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:Lipocalin-2 in acute and chronic liver diseases: focusing on neutrophil-mediated innate immune responses
Investigator(s):Ye D, Wang Y, Wong ICK
Department:Pharmacology & Pharmacy
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:10/2013




Researcher : ZHANG Y

List of Research Outputs

ZHANG Y., Leung S.W.S. and Man R.Y.K., Anti-inflammatory effect of MIR-17-3P via NF-KB pathway in human endothelial cells, Seventeenth Annual Scientific Meeting, The Institute of Cardiovascular Science and Medicine, November 23, 2014, Hong Kong. 2013.
ZHANG Y., Leung S.W.S. and Man R.Y.K., Anti-inflammatory effect of miR-17-3p in human umbilical vein endothelial cells , Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
ZHANG Y., Leung S.W.S. and Man R.Y.K., Role of miR-17-3p in vascular inflammation, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.


Researcher : ZHAO Y

List of Research Outputs

ZHAO Y., Leung S.W.S. and Vanhoutte P.M.G.R., Activation of α1-adrenergic receptors causes thromboxane-prostanoid receptor desensitization in the aorta of the spontaneously hypertensive rat, Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
Zhao Y., Endothelial Nitric Oxide Synthase-Independent Release of Nitric Oxide in the Aorta of the Spontaneously Hypertensive Rat, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.


Researcher : ZOU Q

List of Research Outputs

ZOU Q., Leung S.W.S. and Vanhoutte P.M.G.R., Endogenous acetylcholine contributes to mild hypothermia induced endothelium-dependent relaxations in the SHR aorta, The 12th Meeting of The Asia Pacific Federation of Pharmacologists, Shanghai, China . 2013.


Researcher : Zhao Y

List of Research Outputs

ZHAO Y., Leung S.W.S. and Vanhoutte P.M.G.R., Activation of α1-adrenergic receptors causes thromboxane-prostanoid receptor desensitization in the aorta of the spontaneously hypertensive rat, Experimental Biology 2014, 26 to 30 April 2014, San Diego, CA, USA. 2014.
Zhao Y., Endothelial Nitric Oxide Synthase-Independent Release of Nitric Oxide in the Aorta of the Spontaneously Hypertensive Rat, 18th Research Postgraduate Symposium, December 11-12, 2013, Hong Kong. 2013.


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