DENTAL FACULTY - ORAL BIOSCIENCES
| Researcher : Bandara HMHN |
| List of Research Outputs |
| Bandara H.M.H.N., Cheung B.P.K., Watt R.M., Jin L. and Samaranayake L.P., Secretory products of Escherichia coli biofilm modulate Candida biofilm formation and hyphal development, Journal of Investigative and Clinical Dentistry. 2013, 4: 186-199. |
| Researcher : Chan YK |
| List of Research Outputs |
| Yung C.C.M., Chan Y.K., Lacap-Bugler D.C., Perez-Ortega S., de los Rios-Murillo A., Lee C.K., Cary S.C. and Pointing S.B., Characterization of Chasmoendolithic Community in Miers Valley, McMurdo Dry Valleys, Antarctica, Microbial Ecology. 2014. |
| Researcher : Chen W |
| List of Research Outputs |
| Chen W., Cheng T., Huang J. and Watt R.M., Dissection of biophysical properties and biological activities of Bet/RecT family DNA recombination proteins, Society of General Microbiology Annual Conference, Liverpool UK, 2014. |
| SO L.Y., Chen W., Lacap-Bugler D.C., Seemann M. and Watt R.M., pZMO7-Derived shuttle vectors for heterologous protein expression and proteomic applications in the ethanol-producing bacterium Zymomonas mobilis, BMC Microbiology. BioMed Central, 2014, 14: 68. |
| XIE S., Chen W. and Watt R.M., Biochemical and biological activities of a phage-derived DNA exonuclease and partnering single strand annealing protein (SSAP) from an oral Neisseraiceae, Annual Scientific Meeting, Faculty of Dentistry, University of Hong Kong. 2013. |
| XIE S., Chen W. and Watt R.M., Functional characterization of YqaJ exonuclease and cognate RecT DNA recombination proteins from Kingella oralis, 5th EMBO Meeting, Amsterdam, Netherlands. 2013. |
| Researcher : Cheng T |
| List of Research Outputs |
| Chen W., Cheng T., Huang J. and Watt R.M., Dissection of biophysical properties and biological activities of Bet/RecT family DNA recombination proteins, Society of General Microbiology Annual Conference, Liverpool UK, 2014. |
| Cheng T., XIA W., WANG P., HUANG F., Wang J.J. and Sun H., Histidine-rich proteins in prokaryotes: metal homeostasis and environmental habitat-related occurrence, Metallomics. 2013, 5(10): 1423-1429. |
| Researcher : Epasinghe DJ |
| List of Research Outputs |
| Chu D., Kwan S., Epasinghe D.J., Yiu C.K.Y., Burrow M.F. and Mei L., Synergistic effect of proanthocyanidin and TCP on root caries remineralization. , 2013 Annual Scientific Meeting, Faculty of Dentistry, the University of Hong Kong.. 2013. |
| Epasinghe D.J., Yiu C.K.Y., Burrow M.F. and Tsoi K.H., Effect of flavonoids on biomodification of demineralized dentine., 2013 Annual Scientific Meeting, Faculty of Dentistry, the University of Hong Kong.. 2013. |
| Researcher : Jung HS |
| Project Title: | Development and regeneration; Implications for total and partial reconstruction of the tooth by dental mesenchymal progenitor cells |
| Investigator(s): | Jung HS |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2013 |
| List of Research Outputs |
| Gadi J., Jung S.H., Lee M.J., Jami A., Ruthala K., Kin K.M., Cho N.H., Jung H.S., Kim C.H. and Lim S.K., The transcription factor Sox11 enhances early osteoblast differentiation by facilitating proliferation and the survival of mesenchymal and osteoblast progenitors, Journal of Biological Chemistry. 2013. |
| Green D.W., Fu-Lai W. and Jung H.S., Evolving Marine Biomimetics for Regenerative Dentistry, Marine Drugs. 2014, 12: 2877-2912. |
| Jeon M., Song J.S., Choi B.J., Choi H.J., Shin D.M., Jung H.S. and Kim S.O., In vitro and in vivo characteristics of stem cells from human exfoliated deciduous teeth obtained by enzymatic disaggregation and outgrowth, Archives of Oral Biology. 2014, 59(10): 1013-1023. |
| Jung H.S., "How much do we know about Biotooth", 2013 Hong Kong International Dental Expo and Symposium / Hong Kong. 2013. |
| Jung H.S., Bmp4 associates with tooth root development; implications for root regeneration, 2013 Tripartite Conference on Tooth and Bone / Korea. 2013. |
| Jung H.S., Cell manipulation and tissue regeneration, Innovative Research for Biosis-Abiosis Intelligent Interface Symposium (The 5th International Symposium for Interface Oral Health Science). 2014. |
| Jung H.S., Cytoskeletal Remodelling and Adherens Junctions Regulate Epithelial Morphogenesis in Response to FGF4 Signaling, International Conference of the Korean Society for Molecular and Cellular Biology. 2013. |
| Jung H.S., Kyudai Oral Bioscience. 2014. |
| Jung H.S., National Engineering Laboratory for Oral Regenerative Medicine, Sichuan University. 2013. |
| Kim E.J., Lee M.J., Li L.I.W.E.N., Yoon K.S., Kim K.S. and Jung H.S., Failure of tooth formation mediated by miR-135a overexpression via Bmp signaling, Journal of Dental Research. 2014, 93(6): 571-575. |
| Lai W.F. and Jung H.S., Cell transfection with a b-Cyclodextrin-PEI-Propane-1,2,3 Triol Nanopolymer, PLoS One. 2014, 9(6): e100258. |
| Lai W.F., Lee J.M. and Jung H.S., Molecular and engineering approaches to regenerate and repair teeth in mammals, Cellular and Molecular Life Sciences. 2014, 71(9): 1691-701. |
| Lee H.S., Kim S.H., Kim S.O., Lee J.H., Choi H.J., Jung H.S. and Song J.S., A new type of dental anomaly: molar-incisor malformation (MIM), Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology. 2014, 118(1): 101-109.e3. |
| Lee H.S., Lee J., Kim S.O., Song J.S., Lee J.H., Lee S.I., Jung H.S. and Choi B.J., Comparative gene-expression analysis of the dental folicle and periodontal ligament in humans., PLoS One. 2013, 8(12): e84201. |
| Lee J.M., Kwon H.J., Lai W.F. and Jung H.S., Requirement of Runx3 in pulmonary vasculogenesis, Cell Tissue Research. 2014, 356(2): 445-9. |
| Lee M.J., Ran Byun M., Furutani-Seik M., Hong J.H. and Jung H.S., YAP and TAZ regulate skin wound healing, Journal of Investigative Dermatology. 2014, 134(2): 518-25. |
| Park R., Kim J.H., Choi H., Park Y.B., Jung H.S. and Moon H.S., Effect of alendronate on bone remodeling around implant in the rat, Journal of Advanced Prosthodontics. 2013, 5(4): 374-81. |
| Tsang W.K., Wong P.K., Jung H.S. and Fong W.P., Sub-MIC levels of purpurin inhibit membrane ATPase-mediated proton efflux activity in the human fungal pathogen Candida albicans, Journal of Antibiotics. 2014, 67: 349-350. |
| Researcher : Li NF |
| List of Research Outputs |
| Tsang W.K., Wong P.K., Lam O.L.T., Tsang P.C.S. and Li N.F., Purpurin inhibits biofilm development in non-albicans Candida fungi, Journal of Dental Research. 2013, 92 (Special Issue B): 548. |
| Tsang W.K., Wong P.K., YANG H. and Li N.F., Purpurin triggers caspase-independent apoptosis in Candida dubliniensis biofilms, PLoS ONE. United States of America, 2013, 8: e86032. |
| Researcher : Samaranayake LP |
| Project Title: | 79th General Session and Exhibition of the International Association for Dental Research Turbidometric Evaluation of Polyene-azole Antagonism in C. Albicans |
| Investigator(s): | Samaranayake LP |
| Department: | Dental Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2001 |
| Project Title: | Identification of Immuno-proteome of Candida albicans using a murine candidiasis model |
| Investigator(s): | Samaranayake LP, Seneviratne CJ, Wang Y |
| Department: | Dental Faculty |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2010 |
| Project Title: | Proteomics of a fluconazole resistant, Candida glabrata strain |
| Investigator(s): | Samaranayake LP, Samaranayake YH |
| Department: | Dental Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| Project Title: | Evaluation of biofilm interactions of Candida and gram negative bacteria on the catheter surface |
| Investigator(s): | Samaranayake LP, Samaranayake YH |
| Department: | Dental Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2011 |
| List of Research Outputs |
| Wong S.S.W., Samaranayake L.P. and Seneviratne C.J., In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules, Drug Discovery Today. 2014. |
| Wong S.S.W., Kao R.Y.T., Yuen K.Y., Wang Y., Yang D., Samaranayake L.P. and Seneviratne C.J., In vitro and In vivo activity of a novel antifungal small molecule against Candida infections, PloS one. 2014, 9(1): e85836. |
| Wong S.S.W., Seneviratne C.J., Kao R.Y.T., Yang D., Vizcaino J.A., Alpi E., Egusa H. and Samaranayake L.P., Proposed mechanism of a novel small molecule antifungal for Candida , 2014 IADR General Session. 2014. |
| Researcher : Seneviratne CJ |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Seneviratne CJ |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 12/2011 |
| List of Research Outputs |
| LI H., Seneviratne C.J., Lau A.S.Y., Wang C.Y. and Jin L., Oral commensals and pathogens enhance hBD-2 expression in HOKs, Journal of Dental Research. 2013, 92 (Spec Iss B): 14 (APR). |
| Seneviratne C.J., Lok S., Tong A., Kot C.C.S., Martelli P., Chan T.F., Yim A.K., Yu C., Zhu L., Samaranayake L.P. and Jin L., Common and specific dental plaque microbiomes of human and giant-panda, Journal of Dental Research. 2013, 92 (Spec Iss B): 724 (APR). |
| Tan C.M., Tsoi K.H., Seneviratne C.J. and Matinlinna J.P., Effects of Denture Cleaning by Low-cost Electric Toothbrush, 2nd Meeting of the International Association for Dental Research Asia Pacific Region, Plaza Atheneé, Bangkok, Thailand, 21-23 August 2013. Abstract #103. |
| WANG S., Guo L.I.H.O.N.G., Seneviratne C.J., Huang B., Han J.W.W., Peng L., Liu X. and Zhang C., Biofilm formation of salivary microbiota on dental restorative materials analyzed by denaturing gradient gel electrophoresis and sequencing, Dental Materials Journal. 2014, 33(3): 325-331. |
| Wong S.S.W., Samaranayake L.P. and Seneviratne C.J., In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules, Drug Discovery Today. 2014. |
| Wong S.S.W., Kao R.Y.T., Yuen K.Y., Wang Y., Yang D., Samaranayake L.P. and Seneviratne C.J., In vitro and In vivo activity of a novel antifungal small molecule against Candida infections, PloS one. 2014, 9(1): e85836. |
| Wong S.S.W., Seneviratne C.J., Kao R.Y.T., Yang D., Vizcaino J.A., Alpi E., Egusa H. and Samaranayake L.P., Proposed mechanism of a novel small molecule antifungal for Candida , 2014 IADR General Session. 2014. |
| Researcher : Tsang WK |
| Project Title: | Generation of focused libraries by combinatorial biocatalysis with anti-Candidal activity: synthesis and in vitro study |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Mini Grants |
| Start Date: | 01/2009 |
| Project Title: | Investigation of the functional significance of phytase activity in Candida albicans: gene disruption, pH regulation, and virulence study |
| Investigator(s): | Tsang WK, Samaranayake LP |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 03/2012 |
| Project Title: | Perturbation of pH homeostasis: a comparative study on the inhibitory effect of purpurin on membrane-bound ATPases in Candida albicans |
| Investigator(s): | Tsang WK, Samaranayake LP |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Project Title: | Construction of "arming yeast" for cell surface display of phytase |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2013 |
| Completion Date: | 07/2014 |
| Project Title: | The 5th Congress of European Microbiologists (FEMS2013); Purpurin specifically inhibits Candida albicans efflux pump Cdr2p |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2013 |
| Completion Date: | 07/2013 |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 01/2014 |
| List of Research Outputs |
| Tsang P.C.S., Pow E.H.N., Ip J. and Tsang W.K., Effect of YSGG laser on bacteria adhered to zirconia surfaces, Journal of Dental Research. 2013, 92(Spec Iss B): 181964. |
| Tsang W.K., Editor, Edorium Journal of Dentistry. 2014. |
| Tsang W.K., Wong P.K., Lam O.L.T., Tsang P.C.S. and Li N.F., Purpurin inhibits biofilm development in non-albicans Candida fungi, Journal of Dental Research. 2013, 92 (Special Issue B): 548. |
| Tsang W.K., YANG H. and Tsang P.C.S., Purpurin specifically inhibits Candida albicans efflux pump Cdr2p, FEMS 2013 the 5th Congress of European Microbiologists. 2013. |
| Tsang W.K., Wong P.K., YANG H. and Li N.F., Purpurin triggers caspase-independent apoptosis in Candida dubliniensis biofilms, PLoS ONE. United States of America, 2013, 8: e86032. |
| Tsang W.K., Wong P.K., Jung H.S. and Fong W.P., Sub-MIC levels of purpurin inhibit membrane ATPase-mediated proton efflux activity in the human fungal pathogen Candida albicans, Journal of Antibiotics. 2014, 67: 349-350. |
| YANG H., Tsang P.C.S. and Tsang W.K., Melatonin interferes with the biofilm development in Candida parapsilosis, Journal of Dental Research. 2013, 92 (Special Issue B): 660. |
| Researcher : WONG SWS |
| List of Research Outputs |
| WONG S.W.S., Runner-up, International Association for Dental Research (IADR)/Unilever Divisional Award Competition (South-East Asia division) (Senior category), 2nd IADR-Asia Pacific Region meeting, International Association for Dental Research. 2013. |
| WONG S.W.S., Travel award, 5th Hiroshima Conference on Education and Science in Dentistry , Hiroshima University, Japan. 2013. |
| Researcher : Watt RM |
| Project Title: | Treponema denticola and periodontal disease: novel analytical approaches to probe host-pathogen relationships |
| Investigator(s): | Watt RM, Leung WK, Tanner JA |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2012 |
| Project Title: | Stress response in the oral pathogen Fusobacterium nucleatum: the interplay between polyphosphate metabolism and the stringent response |
| Investigator(s): | Watt RM, Seneviratne CJ, Choi MY |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2012 |
| Completion Date: | 03/2014 |
| Project Title: | Raising the alarmone in Staphylococcus aureus: establishing the molecular basis of the stringent response |
| Investigator(s): | Watt RM, Seneviratne CJ, Tanner JA |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Watt RM |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 01/2013 |
| Project Title: | Molecular analysis of Synergistetes communities associated with chronic and aggressive forms of periodontitis |
| Investigator(s): | Watt RM, Leung WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2013 |
| Project Title: | Whats in your pockets? Single-site analysis of Treponema and Synergistetes populations associated with periodontal health and disease |
| Investigator(s): | Watt RM, Leung WK, Lacap-Bugler DC |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Project Title: | EOMW Aarhus 2014: 11th European Oral icrobiology Workshop; Opening the door to a stable subgingival microbiota |
| Investigator(s): | Watt RM |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2014 |
| Completion Date: | 05/2014 |
| List of Research Outputs |
| ACHARYA A., Mattheos N., Watt R.M., Kheur S., Gopalakrishnan D. and Jin L., Salivary P. gingivalis and PISF IL-1b in periodontally susceptible/non-susceptible individuals, Journal of Dental Research. 2014, 93 (Spec Iss B): 382. |
| Bandara H.M.H.N., Cheung B.P.K., Watt R.M., Jin L. and Samaranayake L.P., Secretory products of Escherichia coli biofilm modulate Candida biofilm formation and hyphal development, Journal of Investigative and Clinical Dentistry. 2013, 4: 186-199. |
| Chen W., Cheng T., Huang J. and Watt R.M., Dissection of biophysical properties and biological activities of Bet/RecT family DNA recombination proteins, Society of General Microbiology Annual Conference, Liverpool UK, 2014. |
| Gao W., You M., Tanner J.A., Leung W.K. and Watt R.M., Development of DNA aptamers against Treponema denticola, Journal of Dental Research. 2014, 93 (Spec Iss B): 388. |
| LU B. and Watt R.M., Comparative biochemical dissection of exopolyphosphatase proteins involved in bacterial polyphosphate metabolism, Annual Scientific Meeting, Faculty of Dentistry, University of Hong Kong. 2013. |
| SO L.Y., Chen W., Lacap-Bugler D.C., Seemann M. and Watt R.M., pZMO7-Derived shuttle vectors for heterologous protein expression and proteomic applications in the ethanol-producing bacterium Zymomonas mobilis, BMC Microbiology. BioMed Central, 2014, 14: 68. |
| Tanner J.A., Cheung Y.W., Watt R.M. and Kotaka M., Loops, hairpins and flipped bases: a DNA aptamer that discriminates Plasmodium lactate dehydrogenase from the blind watchmaker, 9th Annual Meeting of the Oligonucleotide Therapeutics Society, Naples, Italy. 2013. |
| Tanner J.A., Cheung Y.W., KWOK H.C.J., LAW W.L., ALBANO D.R.B., Fung Y.S., Watt R.M. and Kotaka M., Towards aptamer-mediated malaria diagnostics: structural insight into discriminatory molecular recognition by a DNA aptamer, Aptamers in Medicine and Perspectives, Naples, Italy . 2013. |
| Watt R.M., Lacap-Bugler D.C., You M., Gao W. and Leung W.K., Opening the Door to a Stable Microbiota, 11th European Oral Microbiology Workshop, Aarhus, Denmark, 2014. |
| XIE S., Chen W. and Watt R.M., Biochemical and biological activities of a phage-derived DNA exonuclease and partnering single strand annealing protein (SSAP) from an oral Neisseraiceae, Annual Scientific Meeting, Faculty of Dentistry, University of Hong Kong. 2013. |
| XIE S., Chen W. and Watt R.M., Functional characterization of YqaJ exonuclease and cognate RecT DNA recombination proteins from Kingella oralis, 5th EMBO Meeting, Amsterdam, Netherlands. 2013. |
| Xiong L., Teng L.L., Watt R.M., Kan B.I.A.O., Lau S.K.P. and Woo P.C.Y., Arginine deiminase pathway is far more important than urease for acid resistance and intracellular survival in Laribacter hongkongensis: a possible result of arc gene cassette duplication., BMC microbiology. 2014, 14http://www.biomedcentral.com/1471-2180/14/42. |
| You M., GAO W., Tanner J.A., Leung W.K. and Watt R.M., The selection of DNA aptamers against an oral treponeme cell surface protein, Annual Scientific Meeting, Faculty of Dentistry, University of Hong Kong. 2013. |
| ZHUANG L., Lang N.P., Mattheos N., Si M., Lai H.C. and Watt R.M., Periodontal and peri-implant microbiota in patients with both healthy and inflamed peri-implant tissues, Annual Scientific Meeting, Faculty of Dentistry, University of Hong Kong. 2013. |
| ZHUANG L., Watt R.M., Steiner S., LANG-HUA B.H., Wang R., Ramseier C.A. and Lang N.P., Subgingival microbiota of Sri Lankan tea labourers naïve to oral hygiene measures, Journal of Clinical Periodontology. 2014, 41(5): 433-41. |
| Researcher : Wong SSW |
| Project Title: | IADR General Session 2014; Proposed mechanism of a novel small molecule antifungal for Candida |
| Investigator(s): | Wong SSW |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2014 |
| List of Research Outputs |
| Wong S.S.W., Samaranayake L.P. and Seneviratne C.J., In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules, Drug Discovery Today. 2014. |
| Wong S.S.W., Kao R.Y.T., Yuen K.Y., Wang Y., Yang D., Samaranayake L.P. and Seneviratne C.J., In vitro and In vivo activity of a novel antifungal small molecule against Candida infections, PloS one. 2014, 9(1): e85836. |
| Wong S.S.W., Seneviratne C.J., Kao R.Y.T., Yang D., Vizcaino J.A., Alpi E., Egusa H. and Samaranayake L.P., Proposed mechanism of a novel small molecule antifungal for Candida , 2014 IADR General Session. 2014. |
| Researcher : XIE S |
| List of Research Outputs |
| XIE S., Chen W. and Watt R.M., Biochemical and biological activities of a phage-derived DNA exonuclease and partnering single strand annealing protein (SSAP) from an oral Neisseraiceae, Annual Scientific Meeting, Faculty of Dentistry, University of Hong Kong. 2013. |
| XIE S., Chen W. and Watt R.M., Functional characterization of YqaJ exonuclease and cognate RecT DNA recombination proteins from Kingella oralis, 5th EMBO Meeting, Amsterdam, Netherlands. 2013. |
| Researcher : Yip WY |
| List of Research Outputs |
| Seneviratne C.J., Yip W.Y., Chang J.W.W., Zhang C. and Samaranayake L.P., Effect of culture media and nutrients on biofilm growth kinetics of laboratory and clinical strains of Enterococcus faecalis, Archives of Oral Biology. 2013, 58(10): 1327-1334. |