SCHOOL OF CHINESE MEDICINE



Researcher : CHAN WCC

List of Research Outputs

CHAN W.C.C. and Li L., Head Massage Treatment for Senile Insomnia, 7th Taipei Traditional Chinese Medicine International Forum 2015. Taipei, Taiwan.
CHAN W.C.C., LEE S.A.U. .C.H.U.N., LO K.C., WONG H.E.I. .K.I.U. and Li L., Tian Jiu Therapy For the Treatment of Asthma in Adult Patients: A Meta-Analysis, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
CHAN W.C.C., LEE S.A.U. .C.H.U.N., LO K.C., WONG H.E.I. .K.I.U. and Li L., Tian Jiu Therapy for the Treatment of Asthma in Adult Patients: A Meta-Analysis , The Journal of Alternative and Complementary Medicine. 2015, (4): 200–207.
ZHU L., ZHANG W., Wong V.C.W., Ziea E.R.I.C., LO K.C., CHAN W.C.C., Yau T.O. and Li L., Two Years versus One Year of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinical Efficacy Observation Trial, Evidence-Based Complementary and Alternative Medicine. 2015, 2014: 9.
ZHU L., CHAN W.C.C., LO K.C., Yum T.P. and Li L., Wrist-Ankle Acupuncture for the Treatment of Pain Symptoms: A systematic Review and Meta-analysis, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2014, 2014: 9.


Researcher : CHEN H

List of Research Outputs

Chen H. and Lao L., Challenges in Evaluating Acupuncture Trials, In: Lucy Chen, Acupuncture in Pain Management. Nova Science Publishers, 2014, 163-172.
Chen H., Feng Y. and Lao L., Chinese Medicine Higher Education Paper Award (Second Prize) , 全國中醫藥高等教育學會中醫藥高等教育論文二等獎, National CM Higher Education Associaton (CMEA). 全國中醫藥高等教育學會, 2014.
Chen H., Feng Y. and Lao L., Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute, 中西结合医学:香港大学医学院里的中医教育, The 25th Anniversary Foundation Meeting of National CM Higher Education Associaton. 全國中醫藥高等教育學會成 立25周年學術成果報告會, 2014.
Chen H., The important role of TGF-b/Smad in diabetic nephropathy, TGF-~!b/Smad信號在糖尿病腎病中的重要作用, The 1st International Conference of Endocrinology in Chinese Medicine. 世界中醫藥學會內分泌 專業委員會成立大會暨 第一屆國際中醫內分泌 學術論壇, 2014.
Gong J.J., Sun F.M., Li Y.H., Zhou X.L., Duan Z.Z., Duan F.G., ZHAO L., CHEN H., Qi S.H. and Shen J., Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway., Neuropharmacology . 2015, 91: 123-134.
Li X.Z., Chen H., Zheng X. and Liu N., Acupuncture combined with traction therapy for lumbar disc herniation: a systematic review, 針刺配合牽引治療腰椎間盤突出癥的系統評價, Chinese acupuncture & moxibustion. 中國針灸, 2014.
Liu G.X., LI Y.Q., Wei L.H., Zhang Y., Feng M., Meng X.M., Chen H., Shi Y.J. and Lan H.Y., Smad7 inhibits Ang II-mediated hypertensive nephropathy in a mouse model of hypertension, Clinical science (Lond). 2014, 127(3): 195-208.
Wang J., Chu E.S.H., Chen H., Man K., Go M.Y.Y., Huang X.R., Lan H.Y., Sung J.J.Y. and Yu J.U.N., microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway, Oncotarget. 2015, 7325–7338.
Zhang Z. and Chen H., Manic Psychosis, 狂病, Chinese MedicineTextbook of Psychiatry. 中醫神誌病學(供中醫類專業用), Shanghai, Shanghai Scientific & Technical Publishers, 2015, 273-278.
Zhang Z. and Chen H., Obsessive-compulsive Disorder, 強迫症, Chinese MedicineTextbook of Psychiatry. 中醫神誌病學(供中醫類專業用), Shanghai, Shanghai Scientific & Technical Publishers, 2015, 70-75.


Researcher : CHEN X

List of Research Outputs

Chen X., APPL2 ATTENUATES ADULT NEUROGENESIS IN OLFACTORY BULB, XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and XIIth International Conference on Quantification of Brain Function with PET. 2015.
Fu S., GU Y., Jiang J.Q., CHEN X., XU M., Chen X. and Shen J., Calycosin-7-O-β-d-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood–brain barrier integrity in experimental cerebral ischemia–reperfusion injury, Journal of Ethnopharmacology. 2014, 155: 692-701.
Gao L., Zhou Y., Zhong W., Zhao X., Chen C., Chen X., GU Y., Chen J., Lv Z. and Shen J., Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species, Hepatology. 2014, 60: 687-699.
HU J., WONG N.K., YE S., Chen X., LU M., ZHAO Q., GUO Y., Ma C.H., Leung A.Y.H., Shen J. and Yang D., Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In VivoJournal of the American Chemical Society, Journal of the American Chemical Society. 2015, 137: 6837-6843.
LIU J., CHEN X., Tang S.C.W., Lao L., Sze C.W.S., Lee C.K.F. and Zhang Y., Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy, In: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Yanbo Zhang, Journal of Functional Foods [IF 4.48]. 2015, 14(2015): 12-22.
Peng T., WONG N.K., Chen X., Chan Y.K., Ho H.H., Sun Z., HU J., Shen J., El-Nezamy H.S. and Yang D., Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues, Journal of the American Chemical Society. 2014, 140724122145003.
Zhu W., Zheng G., GU Y., CHEN X., Jin Y., Zhang G., Huang J. and Shen J., Clinical efficacy and sEMG analysis of a new traditional Chinese medicine therapy in the treatment of spasticity following apoplectic hemiparalysis., Acta Neurologica Belgica. 2014, 114(2): 125-129.


Researcher : CHEN X

List of Research Outputs

Chen X., APPL2 ATTENUATES ADULT NEUROGENESIS IN OLFACTORY BULB, XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and XIIth International Conference on Quantification of Brain Function with PET. 2015.
Fu S., GU Y., Jiang J.Q., CHEN X., XU M., Chen X. and Shen J., Calycosin-7-O-β-d-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood–brain barrier integrity in experimental cerebral ischemia–reperfusion injury, Journal of Ethnopharmacology. 2014, 155: 692-701.
Gao L., Zhou Y., Zhong W., Zhao X., Chen C., Chen X., GU Y., Chen J., Lv Z. and Shen J., Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species, Hepatology. 2014, 60: 687-699.
HU J., WONG N.K., YE S., Chen X., LU M., ZHAO Q., GUO Y., Ma C.H., Leung A.Y.H., Shen J. and Yang D., Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In VivoJournal of the American Chemical Society, Journal of the American Chemical Society. 2015, 137: 6837-6843.
LIU J., CHEN X., Tang S.C.W., Lao L., Sze C.W.S., Lee C.K.F. and Zhang Y., Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy, In: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Yanbo Zhang, Journal of Functional Foods [IF 4.48]. 2015, 14(2015): 12-22.
Peng T., WONG N.K., Chen X., Chan Y.K., Ho H.H., Sun Z., HU J., Shen J., El-Nezamy H.S. and Yang D., Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues, Journal of the American Chemical Society. 2014, 140724122145003.
Zhu W., Zheng G., GU Y., CHEN X., Jin Y., Zhang G., Huang J. and Shen J., Clinical efficacy and sEMG analysis of a new traditional Chinese medicine therapy in the treatment of spasticity following apoplectic hemiparalysis., Acta Neurologica Belgica. 2014, 114(2): 125-129.


Researcher : CHENG Y

List of Research Outputs

CHENG Y., Tse H.F. and Rong J., Gallic acid-L-leucine conjugate corrects lipid mediator profiles in LPS-stimulated RAW264.7 via suppressing arachidonic acid metabolism, 2014 The 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, August 15, 2014.
CHENG Y., YANG C., ZHAO J., Tse H.F. and Rong J., Proteomic identification of calcium-binding chaperone calreticulin as a potential mediator for the neuroprotective and neuritogenic activities of botanical drug amygdalin,, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, August 27 - 29, 2014.
CHENG Y., YANG C., ZHAO J., Tse H.F. and Rong J., Proteomic identification of calcium-binding chaperone calreticulin as a potential mediator for the neuroprotective and neuritogenic activities of fruit-derived glycoside amygdalin, Journal of Nutritional Biochemistry. 2014, 26: 146-54.
ZHAO J., CHENG Y., YANG C., Lau S.A.M., Lao L., Shuai B., Cai J. and Rong J., Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2, Molecular Neurobiology. 2015.
ZHAO J., CHENG Y., Fan W., YANG C., Ye S., Cui W., Wei W., Lao L., Cai J., Han Y.F. and Rong J., Botanical drug puerarin coordinates with nerve growth factor (NGF) in the regulation of neuronal survival and neuritogenesis via activating ERK1/2 and PI3K/Akt signaling pathways in the neurite extension process, CNS Neuroscience & Therapeutics. 2015, 21: 61-7.


Researcher : CHEUNG F

List of Research Outputs

Wang N., Feng Y., CHEUNG F., Wang X., Zhang Z. and Feng Y., A Chinese Medicine Formula Gegen Qinlian Decoction Suppresses Expansion of Human Renal Carcinoma With Inhibition of Matrix Metalloproteinase-2, Integrative Cancer Therapies. 2014.
Wang N., Feng Y., TAN H.Y., CHEUNG F., HONG M., Lao L. and Nagamatsu T., Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma, Journal of Ethnopharmacology. 2015.
Wang X., Feng Y., Wang N., CHEUNG F., TAN H.Y., Zhong S., Li C. and Kobayashi S., Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy, BioMed Research International. 2014, 2014: 1-14.


Researcher : CHEUNG HP

List of Research Outputs

Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof., European Patent Office. EP 2750684 A1, 2014.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., 从山药分离出的新颖生物活性蛋白及其用途, 中華人民共和國國家知 識產權局, CN103945854 A, 2014.
Sze C.W.S., WONG K.L., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof. (publication no. US 2015/0158919), USPTO. 2015.
WANG S., CHEUNG H.P., Ng T.B., Lao L., Zhang Y. and Sze C.W.S., Screening and Mechanistic Study of Estradiol-stimulating Fractions Derived from Erxian Decoction in Aged Sprague-Dawley Rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
WONG K.L., Wong R.N., ZHANG L., Liu W.K., Ng T.B., Shaw P.C., Kwok P.C.L., Lai Y.M., Zhang Z., Zhang Y., Tong Y., CHEUNG H.P., LU J. and Sze C.W., Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential., Chinese medicine. 2014, 9: 19.
ZHANG L., Ng T.B., Lao L., Zhang Y., CHEUNG H.P. and Sze C.W.S., Aberrantly up-regulated expression of transferrin and ferritin induces iron overload and thereby ovarian aging in Sprague-Dawley rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W.S., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.


Researcher : Chen H

Project Title:The protective role of wfb-120, a novel small molecule from ganoderma lucidum, in renal fibrosis
Investigator(s):Chen H, Lao L, Feng Y, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2015


List of Research Outputs

Chen H. and Lao L., Challenges in Evaluating Acupuncture Trials, In: Lucy Chen, Acupuncture in Pain Management. Nova Science Publishers, 2014, 163-172.
Chen H., Feng Y. and Lao L., Chinese Medicine Higher Education Paper Award (Second Prize) , 全國中醫藥高等教育學會中醫藥高等教育論文二等獎, National CM Higher Education Associaton (CMEA). 全國中醫藥高等教育學會, 2014.
Chen H., Feng Y. and Lao L., Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute, 中西结合医学:香港大学医学院里的中医教育, The 25th Anniversary Foundation Meeting of National CM Higher Education Associaton. 全國中醫藥高等教育學會成 立25周年學術成果報告會, 2014.
Chen H., The important role of TGF-b/Smad in diabetic nephropathy, TGF-~!b/Smad信號在糖尿病腎病中的重要作用, The 1st International Conference of Endocrinology in Chinese Medicine. 世界中醫藥學會內分泌 專業委員會成立大會暨 第一屆國際中醫內分泌 學術論壇, 2014.
Gong J.J., Sun F.M., Li Y.H., Zhou X.L., Duan Z.Z., Duan F.G., ZHAO L., CHEN H., Qi S.H. and Shen J., Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway., Neuropharmacology . 2015, 91: 123-134.
Li X.Z., Chen H., Zheng X. and Liu N., Acupuncture combined with traction therapy for lumbar disc herniation: a systematic review, 針刺配合牽引治療腰椎間盤突出癥的系統評價, Chinese acupuncture & moxibustion. 中國針灸, 2014.
Liu G.X., LI Y.Q., Wei L.H., Zhang Y., Feng M., Meng X.M., Chen H., Shi Y.J. and Lan H.Y., Smad7 inhibits Ang II-mediated hypertensive nephropathy in a mouse model of hypertension, Clinical science (Lond). 2014, 127(3): 195-208.
Wang J., Chu E.S.H., Chen H., Man K., Go M.Y.Y., Huang X.R., Lan H.Y., Sung J.J.Y. and Yu J.U.N., microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway, Oncotarget. 2015, 7325–7338.
Zhang Z. and Chen H., Manic Psychosis, 狂病, Chinese MedicineTextbook of Psychiatry. 中醫神誌病學(供中醫類專業用), Shanghai, Shanghai Scientific & Technical Publishers, 2015, 273-278.
Zhang Z. and Chen H., Obsessive-compulsive Disorder, 強迫症, Chinese MedicineTextbook of Psychiatry. 中醫神誌病學(供中醫類專業用), Shanghai, Shanghai Scientific & Technical Publishers, 2015, 70-75.


Researcher : Chen J

Project Title:The development of multimedia tearching and learning system in TCM -prescrption subject
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:07/2011


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A (ITS/073/11FP)
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:01/2012


Project Title:Ninth AACR-Japanese Cancer Association Joint Conference: Breakthroughs in Basic and Translational Cancer Research; Isoliquiritigenin promotes breast cancer chemosensitivity by limiting cancer stem cells targeting aberrant β-catenin signaling
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:02/2013


Project Title:Exploring cancer preventive function of a dietary compound Isoliquiritigenin by limiting breast cancer stem cells via beta-catenin/COX-2 pathway
Investigator(s):Chen J, Wang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2013


Project Title:Development of Novel Anti-cancer Small Molecules from Natural Herbs Targeting on Lactate Dehydrogenase A
Investigator(s):Chen J, Guan X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2013


Project Title:A randomized, controlled trial of the efficacy of Guolin-Qigong on body-mind health of Chinese women with breast cancer
Investigator(s):Chen J, Ng SM
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014
Completion Date:07/2014


Project Title:Relationships between constitutional types of traditional Chinese medicine and Breast cancer
Investigator(s):Chen J, Sun S
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


Project Title:10 EMAS; An Epidemiological Study of the Relationship between Dietary Patterns of TCM and the Risk of Breast Cancer in Hong Kong Chinese Women(A-676-0004-00358)
Investigator(s):Chen J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2015


Project Title:A novel nanoparticle PBCA-PEG-DOX-ISL target on MDR breast cancer by connecting nanocarrier system and drug combinations
Investigator(s):Chen J, Wang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2015


Project Title:Elucidating anti-angiogenesis effects of Isoliquiritigenin by attenuating endothelial differentiation potential of breast cancer stem cells via Wnt/β-catenin signaling
Investigator(s):Chen J, Wang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2015


List of Research Outputs

Chen J., Wang Z. and Wang D., 雞血藤提取物及其運用和異甘草素的新用途, China Patent. 2014.
Chen J. and JIA L., Exploration and characterization of the Role of Chronic Mild Stress in Promoting Breast Cancer, CGCM (Beijin). 2014.
Chen J., Global Chinese Medicine. 2015.
Chen J., emotion and breast cancer , Professional committee of breast disease PRC. 2014.
Chen J., prescription of TCM (commerciapress inHK. 2015-1, 2015.
Chen J., the popularization TCM in the University of Hong Kong , 2014.
Chen J., the strategy of TCM research , 2011 project annual conference in Chengdu. 2014.
Chen J., 乳癌中醫病機, 乳腺病專業委員會, 2014.
Chen J., 走好中醫科普之路, 2014.
Chen J., 我們在香港做中醫, 2014.
Gao L., Zhou Y., Zhong W., Zhao X., Chen C., Chen X., GU Y., Chen J., Lv Z. and Shen J., Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species, Hepatology. 2014, 60: 687-699.
JIA L., YOU J., Zheng X. and Chen J., Exploration and characterization of the Role of Chronic Mild Stress in Promoting Breast Cancer in Transgenic Mice, 世界中醫會, 2014.
Liu L., Chen J. and Chen Z., Patent No: 61/917,175.Title: Use of Isoflavones for the Treatment of Retroviral Infection, US patent. 2015.
Liu X., Tang H., Chen J., Song C., Yang L. and Liu P., MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple-negative breast cancer, Oncotarget. . 2015.
SUN Y., Liu P. and Chen J., Traditional Chinese Medicine Constitution Analysis as Predictors for Breast Cancer: A Cross-sectional and Case Control Study, manopause2015.
Song C., Liu L., pei X., Liu X., Yang L., Ye F., Chen J., Tang H. and Xie X., miR-200c inhibits breast cancer proliferation by targeting KRAS. , Oncotarget.. 2015.
WANG N., Wang Z., Shen J., Peng C., YOU J., PENG F., Guan X. and Chen J., Dietary compound Isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation, Oncotarget. 2015, 6(12): 9854-9876.
WANG N., Wang Z., Cheng P., YOU J., Han S., Shen J. and Chen J., Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via {beta}-catenin/ABCG2 signaling , Carcinogenesis.. 2014.
Wang Z., WANG N. and Chen J., Caveolin-1 mediates chemoresistance in breast cancer stem cells via β-catenin/ABCG2 signaling pathway, Carcinogenesis. 2014.
Wang Z., WANG N. and Chen J., MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin, Oncotaget. 2014.
Yang L., Tang H., Kong Y., Xie X., Chen J., Song C. and Liu X., LGR5 Promotes Breast Cancer Progression and Maintains Stem-Like Cells Through Activation of Wnt/β-Catenin Signaling, stem cells . 2015.
Zheng X., Loo T.Y. and Chen J., An Epidemiological Study of the Relationship between Dietary Patterns of TCM and the Risk of Breast Cancer in Hong Kong Chinese Women, 2015.


Researcher : Chen X

Project Title:Comparison of different ginsenosides on neurogenesis in vitro and in vivo
Investigator(s):Chen X, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2014
Completion Date:04/2015


Project Title:XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and the XIIth International Conference on Quantification of Brain Function with PET; APPL2 attenuates adult neurogenesis in olfactory bulb
Investigator(s):Chen X
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2015


List of Research Outputs

Chen X., APPL2 ATTENUATES ADULT NEUROGENESIS IN OLFACTORY BULB, XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and XIIth International Conference on Quantification of Brain Function with PET. 2015.
Fu S., GU Y., Jiang J.Q., CHEN X., XU M., Chen X. and Shen J., Calycosin-7-O-β-d-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood–brain barrier integrity in experimental cerebral ischemia–reperfusion injury, Journal of Ethnopharmacology. 2014, 155: 692-701.
Gao L., Zhou Y., Zhong W., Zhao X., Chen C., Chen X., GU Y., Chen J., Lv Z. and Shen J., Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species, Hepatology. 2014, 60: 687-699.
HU J., WONG N.K., YE S., Chen X., LU M., ZHAO Q., GUO Y., Ma C.H., Leung A.Y.H., Shen J. and Yang D., Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In VivoJournal of the American Chemical Society, Journal of the American Chemical Society. 2015, 137: 6837-6843.
LIU J., CHEN X., Tang S.C.W., Lao L., Sze C.W.S., Lee C.K.F. and Zhang Y., Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy, In: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Yanbo Zhang, Journal of Functional Foods [IF 4.48]. 2015, 14(2015): 12-22.
Peng T., WONG N.K., Chen X., Chan Y.K., Ho H.H., Sun Z., HU J., Shen J., El-Nezamy H.S. and Yang D., Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues, Journal of the American Chemical Society. 2014, 140724122145003.
Zhu W., Zheng G., GU Y., CHEN X., Jin Y., Zhang G., Huang J. and Shen J., Clinical efficacy and sEMG analysis of a new traditional Chinese medicine therapy in the treatment of spasticity following apoplectic hemiparalysis., Acta Neurologica Belgica. 2014, 114(2): 125-129.


Researcher : Cheung TS

List of Research Outputs

Cheung T.S., SONG T., Ng T.B., Wu F.H., Lao L., Tang S.C.W., Ho J.C.M., Zhang Y. and Sze C.W.S., Therapeutic Effects of Herbal Chemicals in Traditional Chinese Medicine on Alzheimer's Disease, Curr Med Chem . 2015, 22: 2392-2403.


Researcher : Feng Y

Project Title:Exploring the mechanism underlying the anti-invasion effect of Chinese Medicine Formula Gegen Qinlian Decoction in Human Renal Carcinoma
Investigator(s):Feng Y, Wang N
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2013


Project Title:The inhibitory effect of berberine on tumour associated macrophages in HCC tumour microenvironment
Investigator(s):Feng Y, Wang N
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:04/2014


Project Title:Reprogramming of tumour associated macrophages by baicalin through autophagy mediated IKK-alpha dependent pathway
Investigator(s):Feng Y, Wang N
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2015


Project Title:Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic; Red pigment from Saw palmetto: a natural product for potential alternative cancer treatment
Investigator(s):Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2015
Completion Date:06/2015


List of Research Outputs

Chen H., Feng Y. and Lao L., Chinese Medicine Higher Education Paper Award (Second Prize) , 全國中醫藥高等教育學會中醫藥高等教育論文二等獎, National CM Higher Education Associaton (CMEA). 全國中醫藥高等教育學會, 2014.
Chen H., Feng Y. and Lao L., Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute, 中西结合医学:香港大学医学院里的中医教育, The 25th Anniversary Foundation Meeting of National CM Higher Education Associaton. 全國中醫藥高等教育學會成 立25周年學術成果報告會, 2014.
Feng Y., Member of journal editorship, In: Feng Yibin, Evidence-Based Complementary and Alternative Medicine. USA, Hindawi Publishing Corporation, 2014.
Feng Y., The Editorial Board Member , Recent Patents on Recent Patents on Food, Nutrition & Agriculture. USA, BENTHAM SCIENCE PUBLISHERS LTD., 2014.
Tsang C.M., Cheung K.C., Cheung Y.C., Man K., Lui W.Y.V., Feng Y. and Tsao G.S.W., Berberine suppresses Id-1 expression and inhibits the growth and development of lung metastases in hepatocellular carcinoma, Biochimica et Biophysica Acta. 2014, Epub on 2014-12-08.
Wang L., Wang N., TAN H.Y., Zhang Y. and Feng Y., Protective Effect of a Chinese Medicine Formula He-Ying-Qing-Re Formula on Diabetic Retinopathy, Journal of Ethnopharmacology. 2015.
Wang N., Feng Y., CHEUNG F., Wang X., Zhang Z. and Feng Y., A Chinese Medicine Formula Gegen Qinlian Decoction Suppresses Expansion of Human Renal Carcinoma With Inhibition of Matrix Metalloproteinase-2, Integrative Cancer Therapies. 2014.
Wang N. and Feng Y., Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in State-of-Art, Biomed Res Int.. 2015.
Wang N. and Feng Y., Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in the State of the Art, BioMed Research International. 2015, 2015: 1-14.
Wang N., Feng Y., TAN H.Y., CHEUNG F., HONG M., Lao L. and Nagamatsu T., Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma, Journal of Ethnopharmacology. 2015.
Wang N., TAN H.Y. and Feng Y., Suppression of nascent protein synthesis by natural product berberine, 19th World Congress on Advances in Oncology & 17th International symposium on Molecular Medicine. 2014.
Wang X., Feng Y., Wang N., CHEUNG F., TAN H.Y., Zhong S., Li C. and Kobayashi S., Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy, BioMed Research International. 2014, 2014: 1-14.
Xu B., Wang N., Pan W., Qiu J., Cao P., ZHU M., Feng Y. and Liang G., Synthesis and anti-tumor activity evaluation of Matijin-Su derivatives, Bioorganic Chemistry. 2014, 56: 34-40.


Researcher : Fu S

List of Research Outputs

Fu S., GU Y., Jiang J.Q., CHEN X., XU M., Chen X. and Shen J., Calycosin-7-O-β-d-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood–brain barrier integrity in experimental cerebral ischemia–reperfusion injury, Journal of Ethnopharmacology. 2014, 155: 692-701.


Researcher : GU Y

List of Research Outputs

Fu S., GU Y., Jiang J.Q., CHEN X., XU M., Chen X. and Shen J., Calycosin-7-O-β-d-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood–brain barrier integrity in experimental cerebral ischemia–reperfusion injury, Journal of Ethnopharmacology. 2014, 155: 692-701.
GU Y., Lee W.S. and Shen J., Site-2 protease responds to oxidative stress and regulates oxidative injury in mammalian cells. , Scientific Reports . 2014, 4:: 6268.
Gao L., Zhou Y., Zhong W., Zhao X., Chen C., Chen X., GU Y., Chen J., Lv Z. and Shen J., Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species, Hepatology. 2014, 60: 687-699.
Zhu W., Zheng G., GU Y., CHEN X., Jin Y., Zhang G., Huang J. and Shen J., Clinical efficacy and sEMG analysis of a new traditional Chinese medicine therapy in the treatment of spasticity following apoplectic hemiparalysis., Acta Neurologica Belgica. 2014, 114(2): 125-129.


Researcher : Gao L

List of Research Outputs

Gao L., Zhou Y., Zhong W., Zhao X., Chen C., Chen X., GU Y., Chen J., Lv Z. and Shen J., Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species, Hepatology. 2014, 60: 687-699.


Researcher : HONG M

List of Research Outputs

Wang N., Feng Y., TAN H.Y., CHEUNG F., HONG M., Lao L. and Nagamatsu T., Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma, Journal of Ethnopharmacology. 2015.


Researcher : HUNG HB

List of Research Outputs

Man M.S.C., HUNG H.B., Ng R., Yu X.C., Cheung H., Fung P.M., Li L.S.W., Leung K.P., Leung K.P., Tsang W.K., Ziea E., Wong V.C.W. and Zhang Z., A pilot controlled trial of a combination of dense cranial electroacupuncture stimulation and body acupuncture for post-stroke depression, In: Tom Rowles, BMC Complementary and Alternative Medicine. London, UK, BioMed Central, 2014, 14: 255.


Researcher : Hu KY

Project Title:The 6th World Congress of Chinese Medicine 2009 The International Spread Characteristics of Traditional Chinese Medicine
Investigator(s):Hu KY
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2009




Researcher : JIA L

List of Research Outputs

Chen J. and JIA L., Exploration and characterization of the Role of Chronic Mild Stress in Promoting Breast Cancer, CGCM (Beijin). 2014.
JIA L., YOU J., Zheng X. and Chen J., Exploration and characterization of the Role of Chronic Mild Stress in Promoting Breast Cancer in Transgenic Mice, 世界中醫會, 2014.


Researcher : LEIGH AB

List of Research Outputs

LEIGH A.B., Lai Y.M., Zhang Y., Lao L. and Sze C.W.S., Comparison of effectiveness between CAM118 granules and granule mixtures of its individual herbs at different temperatures on human colon carcinoma HT-29 cells , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
LEIGH A.B., Lai Y.M., Ng T.B., Tong Y. and Sze C.W., Science-based Holistic Philosophy of Chinese Medicine Formula: Reflected in cytotoxicity of Tian-xian Liquid (in vitro) and the protein expression of p21, MMP-1 andMDR-1 in Human Colorectal Carcinoma (in vivo) in Response to Tian-xian Liquid., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
LEIGH A.B., Lai Y.M., Ng T.B., Tong Y. and Sze C.W.S., Science-based Holistic Philosophy of Chinese Medicine Formula: Reflecting in cytotoxicity (in vitro) and the protein expression of p21, MMP-1 and MDR-1 (in vivo) of Tian-xian Liquid in Human Colorectal Carcinoma , 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
Sze C.W., LU J., Lai Y.M., WONG K.L., Lao L., LEIGH A.B., ZHANG L., Zhang Y. and Ng T.B., The Magic of Chinese Yam, ITC InnoCarnival 2013. 2014.


Researcher : LIN X

List of Research Outputs

LIN X., LIU J., Chung W.Y., Sze C.W.S., Li H.Y., Lao L. and Zhang Y., Polysaccharides of Dendrobium officinale induce aquaporin 5 translocation by activating M3 muscarinic receptors, Planta Med . 2015, 81: 130-137.


Researcher : LIU J

List of Research Outputs

LIN X., LIU J., Chung W.Y., Sze C.W.S., Li H.Y., Lao L. and Zhang Y., Polysaccharides of Dendrobium officinale induce aquaporin 5 translocation by activating M3 muscarinic receptors, Planta Med . 2015, 81: 130-137.
LIU J., Sze C.W.S., Lee C.K.F. and Zhang Y., Abstract and poster presentation: Aquaporin9 is a promising novel biomarker and therapeutic target for Alzheimer's disease. , In: Liu JY, Sze CW, Lee KF. Zhang YB*., Cell Symposia: Translational Neuroscience 2014. Nov 13-14, 2014. Arlington, VA, USA. Organization by the editors of Cell Press's leading journals. 2014.11.13-14. . 2014, P2.39.
LIU J., CHEN X., Tang S.C.W., Lao L., Sze C.W.S., Lee C.K.F. and Zhang Y., Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy, In: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Yanbo Zhang, Journal of Functional Foods [IF 4.48]. 2015, 14(2015): 12-22.
LIU J., Tang S.C.W., Sze C.W.S., Lao L., Ho J.C.M., Lee C.K.F. and Zhang Y., Paper and poster presentation: Traditional Chinese Medicine is a Promising Alternative for the Management of Diabetic Nephropathy. , In: Liu JY, Tang SCW, Sze SCW, Lao LX, Ho JCM, Lee CKF, Zhang YB*. , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum, The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research 15 -16/11/2014, Hong Kong. Organized by Commission of Free Radical Biology and Medicine, Biophysical Society of China and Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014.11.15-16. . 2014, p-60.
Liu J., Petersen N.J., Lee C.K.F., Hansen S.H., Lao L., Sze C.W. and Zhang Y., Application of temperature-correlated mobility theory for optimizing the MEKC separation of the main lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoction, Electrophoresis. 2014.
Zhang Y., Sze C.W.S., Tang S.C.W., Ho J.C.M., SONG T. and LIU J., Invention of Efficacy on Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation Though Experimental Rats. , In: Zhang YB*, Sze CW, Tang CW, Ho CW, Song TH, Liu JY., China patent office. 2014.


Researcher : LO KC

List of Research Outputs

CHAN W.C.C., LEE S.A.U. .C.H.U.N., LO K.C., WONG H.E.I. .K.I.U. and Li L., Tian Jiu Therapy For the Treatment of Asthma in Adult Patients: A Meta-Analysis, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
CHAN W.C.C., LEE S.A.U. .C.H.U.N., LO K.C., WONG H.E.I. .K.I.U. and Li L., Tian Jiu Therapy for the Treatment of Asthma in Adult Patients: A Meta-Analysis , The Journal of Alternative and Complementary Medicine. 2015, (4): 200–207.
LO K.C. and Li L., The influence of the Philosophical Concept of “Changes” in “ZhouYi” on Traditional Chinese Medicine Theories, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
Yum T.P., LO K.C. and Li L., Literature Review on Acupuncture Sensation in Different Acupoints, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
ZHU L., LO K.C. and Li L., Review of Clinical Research for Tian Jiu Therapy on Asthma, China Journal of Chinese Medicine. 2015, (6): 34-37.
ZHU L., LO K.C. and Li L., The Analysis of Factors Influencing Tian Jiu Therapy on Asthma, Guangming Journal of Chinese Medicine. 2014, (8): 1794-1796.
ZHU L., ZHANG W., Wong V.C.W., Ziea E.R.I.C., LO K.C., CHAN W.C.C., Yau T.O. and Li L., Two Years versus One Year of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinical Efficacy Observation Trial, Evidence-Based Complementary and Alternative Medicine. 2015, 2014: 9.
ZHU L., CHAN W.C.C., LO K.C., Yum T.P. and Li L., Wrist-Ankle Acupuncture for the Treatment of Pain Symptoms: A systematic Review and Meta-analysis, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2014, 2014: 9.


Researcher : LU J

List of Research Outputs

LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, In: Tianhe SONG, Kalin Yanbo ZHANG*. , The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Aug 27-30, 2014. Beijing, China. Organization by China Academy of Chinese Material Science and Institute of Chinese Material Medica, CACMS. Bejing, China. P332. . 2014.
Sze C.W., LU J., Lai Y.M., WONG K.L., Lao L., LEIGH A.B., ZHANG L., Zhang Y. and Ng T.B., The Magic of Chinese Yam, ITC InnoCarnival 2013. 2014.
WONG K.L., Wong R.N., ZHANG L., Liu W.K., Ng T.B., Shaw P.C., Kwok P.C.L., Lai Y.M., Zhang Z., Zhang Y., Tong Y., CHEUNG H.P., LU J. and Sze C.W., Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential., Chinese medicine. 2014, 9: 19.


Researcher : Lao L

Project Title:2014 International Research Congress on Integrative Medicine and Health; Acupuncture and Complementary Medicine in Pain Management/Acupuncture and Mindfulness-Based Stress Reduction among Female Child Abuse Survivors: A Randomized Waitlist-Controlled Pilot Study
Investigator(s):Lao L
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2014


Project Title:Distal acupoint stimulation sensitizes peripheral mast cells to osteoarthritis synovium via adenosine signaling
Investigator(s):Lao L, Chen H, Yeung YF
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2015


List of Research Outputs

Chen H. and Lao L., Challenges in Evaluating Acupuncture Trials, In: Lucy Chen, Acupuncture in Pain Management. Nova Science Publishers, 2014, 163-172.
Chen H., Feng Y. and Lao L., Chinese Medicine Higher Education Paper Award (Second Prize) , 全國中醫藥高等教育學會中醫藥高等教育論文二等獎, National CM Higher Education Associaton (CMEA). 全國中醫藥高等教育學會, 2014.
Chen H., Feng Y. and Lao L., Chinese integrative medicine: inclusion of a Chinese medicine programme in a conventional medical institute, 中西结合医学:香港大学医学院里的中医教育, The 25th Anniversary Foundation Meeting of National CM Higher Education Associaton. 全國中醫藥高等教育學會成 立25周年學術成果報告會, 2014.
Cheung T.S., SONG T., Ng T.B., Wu F.H., Lao L., Tang S.C.W., Ho J.C.M., Zhang Y. and Sze C.W.S., Therapeutic Effects of Herbal Chemicals in Traditional Chinese Medicine on Alzheimer's Disease, Curr Med Chem . 2015, 22: 2392-2403.
LEIGH A.B., Lai Y.M., Zhang Y., Lao L. and Sze C.W.S., Comparison of effectiveness between CAM118 granules and granule mixtures of its individual herbs at different temperatures on human colon carcinoma HT-29 cells , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
LIN X., LIU J., Chung W.Y., Sze C.W.S., Li H.Y., Lao L. and Zhang Y., Polysaccharides of Dendrobium officinale induce aquaporin 5 translocation by activating M3 muscarinic receptors, Planta Med . 2015, 81: 130-137.
LIU J., CHEN X., Tang S.C.W., Lao L., Sze C.W.S., Lee C.K.F. and Zhang Y., Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy, In: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Yanbo Zhang, Journal of Functional Foods [IF 4.48]. 2015, 14(2015): 12-22.
LIU J., Tang S.C.W., Sze C.W.S., Lao L., Ho J.C.M., Lee C.K.F. and Zhang Y., Paper and poster presentation: Traditional Chinese Medicine is a Promising Alternative for the Management of Diabetic Nephropathy. , In: Liu JY, Tang SCW, Sze SCW, Lao LX, Ho JCM, Lee CKF, Zhang YB*. , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum, The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research 15 -16/11/2014, Hong Kong. Organized by Commission of Free Radical Biology and Medicine, Biophysical Society of China and Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014.11.15-16. . 2014, p-60.
LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, In: Tianhe SONG, Kalin Yanbo ZHANG*. , The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Aug 27-30, 2014. Beijing, China. Organization by China Academy of Chinese Material Science and Institute of Chinese Material Medica, CACMS. Bejing, China. P332. . 2014.
Lao L. and Yeung W.F., Treating chronic knee pain with acupuncture (Letter to Editor), JAMA. 2015, 313: 627-8.
Lin X.I.A.N.G., Liu J.I.N.G.Y.I., Chung W.I.N.G.Y.A.N., Li H.A.N.Y.A.N., Lao L. and Zhang Y., Polysaccharides of Dendrobium officinale Induce AQP-5 Translocation by Activating M3 Muscarinic Receptor, In: Xiang Lin, Jingyi Liu, Wingyan Chung, Stephen Cho-Wing Sze, Haiyan Li, Lixing Lao, Yanbo Zhang, Planta Medica . 2015, 2(81):130-137.
Liu J., Petersen N.J., Lee C.K.F., Hansen S.H., Lao L., Sze C.W. and Zhang Y., Application of temperature-correlated mobility theory for optimizing the MEKC separation of the main lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoction, Electrophoresis. 2014.
Sze C.W., LU J., Lai Y.M., WONG K.L., Lao L., LEIGH A.B., ZHANG L., Zhang Y. and Ng T.B., The Magic of Chinese Yam, ITC InnoCarnival 2013. 2014.
WANG S., Ng T.B., Lao L. and Sze C.W., Combing Network Phytochemistry with Networking Pharmacology Approaches to Elucidate the Action Mechanism of Traditional Chinese Medicine Formula: Chemical Constitutes of Erxian Decoction Up-Regulated Estrogen Receptor Expression and Induced Estradiol-Biosynthesis for Menopause as a Study Model., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
WANG S., Ng T.B., Lao L. and Sze C.W.S., Combing Network Phytochemistry with Networking Pharmacology Approaches to Elucidate the Action Mechanism of Traditional Chinese Medicine Formula: Chemical Constitutes of Erxian Decoction Up-Regulated Estrogen Receptor Expression and Induced Estradiol-Biosynthesis for Menopause as a Study Model, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
WANG S., CHEUNG H.P., Ng T.B., Lao L., Zhang Y. and Sze C.W.S., Screening and Mechanistic Study of Estradiol-stimulating Fractions Derived from Erxian Decoction in Aged Sprague-Dawley Rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
Wang N., Feng Y., TAN H.Y., CHEUNG F., HONG M., Lao L. and Nagamatsu T., Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma, Journal of Ethnopharmacology. 2015.
ZHANG L., Ng T.B., Lao L., Zhang Y., CHEUNG H.P. and Sze C.W.S., Aberrantly up-regulated expression of transferrin and ferritin induces iron overload and thereby ovarian aging in Sprague-Dawley rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W.S., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
ZHAO J., CHENG Y., YANG C., Lau S.A.M., Lao L., Shuai B., Cai J. and Rong J., Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2, Molecular Neurobiology. 2015.
ZHAO J., CHENG Y., Fan W., YANG C., Ye S., Cui W., Wei W., Lao L., Cai J., Han Y.F. and Rong J., Botanical drug puerarin coordinates with nerve growth factor (NGF) in the regulation of neuronal survival and neuritogenesis via activating ERK1/2 and PI3K/Akt signaling pathways in the neurite extension process, CNS Neuroscience & Therapeutics. 2015, 21: 61-7.
ZHAO J., Lao L. and Rong J., Plant natural product puerarin suppressed 6-hydroxydopamine (6-OHDA)-induced neurotoxicity via inducing mitochondrial enzyme arginase-2, the XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and the XIIth International Conference on Quantification of Brain Function with PET, Vancouver, British Columbia, June 27-30, 2015.


Researcher : Lee WS

List of Research Outputs

GU Y., Lee W.S. and Shen J., Site-2 protease responds to oxidative stress and regulates oxidative injury in mammalian cells. , Scientific Reports . 2014, 4:: 6268.


Researcher : Li L

Project Title:Efficacy Observation on Tian Jiu Therapy for Asthma
Investigator(s):Li L, Lao L, Cherny SS
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


Project Title:A Systematic Study of Acupuncture Manipulation in Yellow Emperor’s Canon of Medicine
Investigator(s):Li L
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2015


List of Research Outputs

CHAN W.C.C. and Li L., Head Massage Treatment for Senile Insomnia, 7th Taipei Traditional Chinese Medicine International Forum 2015. Taipei, Taiwan.
CHAN W.C.C., LEE S.A.U. .C.H.U.N., LO K.C., WONG H.E.I. .K.I.U. and Li L., Tian Jiu Therapy For the Treatment of Asthma in Adult Patients: A Meta-Analysis, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
CHAN W.C.C., LEE S.A.U. .C.H.U.N., LO K.C., WONG H.E.I. .K.I.U. and Li L., Tian Jiu Therapy for the Treatment of Asthma in Adult Patients: A Meta-Analysis , The Journal of Alternative and Complementary Medicine. 2015, (4): 200–207.
LO K.C. and Li L., The influence of the Philosophical Concept of “Changes” in “ZhouYi” on Traditional Chinese Medicine Theories, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
Li L., Seeking Luck, Avoiding Calamity, and Choosing Time for Acupuncture: Impact of Nine-palaces and Eight-winds Theory on Traditional Time-acupuncture Methodology, 7th Taipei Traditional Chinese Medicine International Forum 2015. Taipei, Taiwan.
Li L., Chronotherapeutics of Acupuncture & Moxibustion (Revised in traditional Chinese version and hardcover) . 針灸時間治療學(修訂繁體精裝本), Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 452.
Li L., Chronotherapeutics of Acupuncture & Moxibustion (Revised in traditional Chinese version) . 針灸時間治療學(修訂繁體版), Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 452.
Li L., Chronotherapeutics of Acupuncture & Moxibustion (Revised version in hardcover) . 針灸時間治療學(修訂精裝本), Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 452.
Li L., Chronotherapeutics of Acupuncture & Moxibustion (Revised version) . 針灸時間治療學(修訂版), Taiyuan, Shanxi, Shanxi Science & Technology Publishing House, 2014, 452.
Li L., History of Chinese Medicine Culture. 中醫文化史話, Shanghai, Shanghai Scientific & Technical Publishers, 2015, 246.
Li L., Seeking Luck, Avoiding Calamity, and Choosing Time for Acupuncture: Impact of Nine-palaces and Eight-winds Theory on Traditional Time-acupuncture Methodology, Chinese Traditional Culture. 2015, (3): 7-10.
Li L., The Acupuncture Manipulation of Multi-needles at One Acupoint in the Context of Eliminating Evil-qi, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
Li L., The Truth of Medical Knowledge. 醫道求真, Shanghai, Shanghai Scientific & Technical Publishers, 2015, 221.
Li L., Treatment of Wintertime Diseases in Summer and SanFuTianJiu, In: Shenzhen Hospital of University of Hong Kong, Health Seminar. Shenzhen, China, 2015.
To Y.T. and Li L., A Single Case Study – Acupuncture in the Treatment of Thoracic Outlet Syndrome, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
Yum T.P., LO K.C. and Li L., Literature Review on Acupuncture Sensation in Different Acupoints, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
ZHU L., LO K.C. and Li L., Review of Clinical Research for Tian Jiu Therapy on Asthma, China Journal of Chinese Medicine. 2015, (6): 34-37.
ZHU L., LO K.C. and Li L., The Analysis of Factors Influencing Tian Jiu Therapy on Asthma, Guangming Journal of Chinese Medicine. 2014, (8): 1794-1796.
ZHU L., ZHANG W., Wong V.C.W., Ziea E.R.I.C., LO K.C., CHAN W.C.C., Yau T.O. and Li L., Two Years versus One Year of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinical Efficacy Observation Trial, Evidence-Based Complementary and Alternative Medicine. 2015, 2014: 9.
ZHU L., CHAN W.C.C., LO K.C., Yum T.P. and Li L., Wrist-Ankle Acupuncture for the Treatment of Pain Symptoms: A systematic Review and Meta-analysis, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2014, 2014: 9.


Researcher : Liu C

Project Title:6th Annual Rocky Mountain Bioinformatics Conference CADEG, a Set of Software Tools for High Resolution Identification of Potential Chromosomal Abnormalities
Investigator(s):Liu C
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:12/2008




Researcher : Liu KJ

List of Research Outputs

Qi Z., Yan F., Shi W., Zhang C., Dong W., Zhao Y., Shen J., Ji X., Liu K.J. and Luo Y.M., AKT-related autophagy contributes to the neuroprotective efficacy of Hydroxysafflor Yellow A against ischemic stroke in rats., Translational Stroke Research 5(4):501-9, 2014. 2014.


Researcher : Liu N

List of Research Outputs

Li X.Z., Chen H., Zheng X. and Liu N., Acupuncture combined with traction therapy for lumbar disc herniation: a systematic review, 針刺配合牽引治療腰椎間盤突出癥的系統評價, Chinese acupuncture & moxibustion. 中國針灸, 2014.


Researcher : Loo TY

List of Research Outputs

Zheng X., Loo T.Y. and Chen J., An Epidemiological Study of the Relationship between Dietary Patterns of TCM and the Risk of Breast Cancer in Hong Kong Chinese Women, 2015.


Researcher : Man MSC

List of Research Outputs

Man M.S.C., HUNG H.B., Ng R., Yu X.C., Cheung H., Fung P.M., Li L.S.W., Leung K.P., Leung K.P., Tsang W.K., Ziea E., Wong V.C.W. and Zhang Z., A pilot controlled trial of a combination of dense cranial electroacupuncture stimulation and body acupuncture for post-stroke depression, In: Tom Rowles, BMC Complementary and Alternative Medicine. London, UK, BioMed Central, 2014, 14: 255.


Researcher : Ng TB

List of Research Outputs

LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, In: Tianhe SONG, Kalin Yanbo ZHANG*. , The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Aug 27-30, 2014. Beijing, China. Organization by China Academy of Chinese Material Science and Institute of Chinese Material Medica, CACMS. Bejing, China. P332. . 2014.


Researcher : PENG F

List of Research Outputs

WANG N., Wang Z., Shen J., Peng C., YOU J., PENG F., Guan X. and Chen J., Dietary compound Isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation, Oncotarget. 2015, 6(12): 9854-9876.


Researcher : Rong J

Project Title:The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy
Investigator(s):Rong J
Department:LKS Medical Faculty
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2006


Project Title:Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) for the resolution of neutrophil-induced myocardial injury
Investigator(s):Rong J, Lau ASY, Li XC, Tse HF, Xia Z
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2012


Project Title:Biological characterization of botanical non-steroidal progesterone receptor modulator puerarin for potentiating nerve growth factor (NGF)-induced neuritogenesis
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


Project Title:N-Propargyl caffeamide promotes macrophage transformation from inflammatory M1 to anti-inflammatory M2 phenotypes in the context of myocardial infarction
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2015


Project Title:The XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and the XIIth International Conference on Quantification of Brain Function with PET ; Plant natural product puerarin suppressed 6-hydroxydopamine (6-OHDA)-induced neurotoxicity via inducing mitochondrial enzyme arginase-2
Investigator(s):Rong J
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2015


List of Research Outputs

CHENG Y., Tse H.F. and Rong J., Gallic acid-L-leucine conjugate corrects lipid mediator profiles in LPS-stimulated RAW264.7 via suppressing arachidonic acid metabolism, 2014 The 10th International Postgraduate Symposium on Chinese Medicine, Hong Kong Convention and Exhibition Center, Hong Kong, August 15, 2014.
CHENG Y., YANG C., ZHAO J., Tse H.F. and Rong J., Proteomic identification of calcium-binding chaperone calreticulin as a potential mediator for the neuroprotective and neuritogenic activities of botanical drug amygdalin,, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, August 27 - 29, 2014.
CHENG Y., YANG C., ZHAO J., Tse H.F. and Rong J., Proteomic identification of calcium-binding chaperone calreticulin as a potential mediator for the neuroprotective and neuritogenic activities of fruit-derived glycoside amygdalin, Journal of Nutritional Biochemistry. 2014, 26: 146-54.
Rong J., Networking the Active Compounds From Chinese Medicines and Molecular Targets in Mammalian Cells for Drug Discovery in the Post-Genomic Era, the 12th Annual Congress of International Drug Discovery Science and Technology (IDDST-2014), November 18-20, 2014, Tongli Lakeview Hotel, Suzhou, China. 2014.
Shuai B., Yang Y.P., Shen L., Zhu R., Xu X.J., Ma C., Lv L., ZHAO J. and Rong J., Local renin-angiotensin system is associated with bone mineral density of glucocorticoid-induced osteoporosis patients, Osteoporosis International. 2015, 26: 1063-1071.
YANG C., Li X.C. and Rong J., Amygdalin isolated from Semen Persicae (Tao Ren) extracts induces the expression of follistatin in HepG2 and C2C12 cell lines, Chinese Medicine. 2014, 9: 23.
YANG C. and Rong J., Click chemistry-assisted identification of caffeic acid propargylamide (CAPA)-modified protein Keap1 demonstrates a general mechanism underlying the neuroprotective and neuritogenic activities of o-catechol-bearing natural products, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research, Hong Kong, China, November 15-16, 2014.
ZHAO J., Han Y. and Rong J., Botanical C-glucosylated isoflavone puerarin suppresses nitric oxide-induced neurotoxicity via inducing arginase-2 expression, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, August 27 - 29, 2014.
ZHAO J., CHENG Y., YANG C., Lau S.A.M., Lao L., Shuai B., Cai J. and Rong J., Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2, Molecular Neurobiology. 2015.
ZHAO J., CHENG Y., Fan W., YANG C., Ye S., Cui W., Wei W., Lao L., Cai J., Han Y.F. and Rong J., Botanical drug puerarin coordinates with nerve growth factor (NGF) in the regulation of neuronal survival and neuritogenesis via activating ERK1/2 and PI3K/Akt signaling pathways in the neurite extension process, CNS Neuroscience & Therapeutics. 2015, 21: 61-7.
ZHAO J. and Rong J., Pharmacological Induction of Arginase II by C-glucosylated Isoflavonone Puerarin Suppresses Nitric Oxide-induced Mitochondrial Dysfunction in Differentiated Neuronal PC12 Cells, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research, Hong Kong, China, November 15-16, 2014.
ZHAO J. and Rong J., Pharmacological induction of arginase II by C-glucosylated isoflavonone puerarin suppresses nitric oxide-induced mitochondrial dysfunction in differentiated neuronal PC12 cells, Experimental Biology 2015, Boston, MA, USA, March 28-April 1, 2015.. 2015.
ZHAO J., Lao L. and Rong J., Plant natural product puerarin suppressed 6-hydroxydopamine (6-OHDA)-induced neurotoxicity via inducing mitochondrial enzyme arginase-2, the XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and the XIIth International Conference on Quantification of Brain Function with PET, Vancouver, British Columbia, June 27-30, 2015.


Researcher : SONG T

List of Research Outputs

Cheung T.S., SONG T., Ng T.B., Wu F.H., Lao L., Tang S.C.W., Ho J.C.M., Zhang Y. and Sze C.W.S., Therapeutic Effects of Herbal Chemicals in Traditional Chinese Medicine on Alzheimer's Disease, Curr Med Chem . 2015, 22: 2392-2403.
SONG T. and Zhang Y., Abstract and poster presentation: Enhanced antitumor effect of dendrobine combined with cisplatin for treating non-small cell lung cancer. , In: Song TH, Zhang KYB*. , Conference in Translation of the Cancer Genome. February 7-9, 2015, Fairmont San Francisco, San Francisco, California. Organization by American Association for Cancer Research. 2015.02.07-09. . 2015, A2-69.
SONG T. and Zhang Y., Abstract and poster presentation: Investigation on the anti-inflammatory activity and mechanism of Dendrobium extract in vitro and in vivo. P332. , In: Song TH, Zhang YB* , 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Organizer by China Academy of Chinese Medical Sciences. International Conference Centre. Bejing, China. 2014.08.27-30.. 2014, p332.
SONG T., Sze C.W.S., Ng T.B., Tang S.C.W., Ho J.C.M. and Zhang Y., Session 3 Chairman. Speaking and abstract: Investigation of Effect Mechanisms and Clinical Study of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced COPD. , In: Song TH, Sze CW, Ng TB, Tang CW, Ho CM, Zhang YB*. , Shanghai, China. Co-organized by the Phytochemical Society of Europe and the Phytochemical Society of Asia. Jun 26-29, 2015. . 2015, p-18.
Zhang Y., Sze C.W.S., Tang S.C.W., Ho J.C.M., SONG T. and LIU J., Invention of Efficacy on Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation Though Experimental Rats. , In: Zhang YB*, Sze CW, Tang CW, Ho CW, Song TH, Liu JY., China patent office. 2014.


Researcher : SUN Y

List of Research Outputs

SUN Y., Liu P. and Chen J., Traditional Chinese Medicine Constitution Analysis as Predictors for Breast Cancer: A Cross-sectional and Case Control Study, manopause2015.


Researcher : Shen J

Project Title:Biochemical Society Meeting 679 University of Essex UK - Stress, Signalling and Control Reactive Oxygen Species Mediate Intracellular Cholesterol Accumulation via Modulating Caveolin-1 Pathway in Chinese Hamster Ovary Cells
Investigator(s):Shen J
Department:Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2003


Project Title:Elucidating caveolin-1 as a negative modulating protein for proliferation of neural stem/progenitor cells and neural differentiation in post-ischemic brain
Investigator(s):Shen J, Chung SK, So KF
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2010


Project Title:Molecular regulations of reactive nitrogen species inhibitors for preventing thrombolysis-induced blood brain barrier disruption and hemorrhagic transformation in experimental cererbal ischemia-reperfersion models
Investigator(s):Shen J, Cheung RTF, Chung SK, Siu DCW, Yang D
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011
Completion Date:09/2014


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating proliferation and neuronal differentiation of neural stem/progenitor cells under hypoxic and ischemic conditions
Investigator(s):Shen J, Chung SK, So KF, Yang D
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2012


Project Title:Elucidating peroxynitrite as a cellular signaling molecule for regulating neurogenesis under hypoxic and ischemic conditions
Investigator(s):Shen J, Yang D, Chen X
Department:School of Chinese Medicine
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2013


Project Title:Exploration of dietary compound isoliquiritigenin in chemosensitizing breast cancer stem cells by targeting aberrant β–catenin signalling
Investigator(s):Shen J, Chen J, Wang Z
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:11/2013


Project Title:Elucidating effects of APPL2 on regulating proliferation and cell fate decision of neural stem/progenitor cells through activating Notch signaling pathway
Investigator(s):Shen J, So KF, Chung SK
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Roles of Caveolin-1 in Regulating T lymphocytes Infiltration through Blood Brain Barrier in Pathological Process of Experimental Autoimmune Encephalomyelitis
Investigator(s):Shen J, Chan GCF, Wu W
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


Project Title:Exploring Caveolin-1 as a Novel Molecular Target for Hampering T lymphocytes Infiltration through Blood Brain Barrier and Attenuating Disease Progress in Experimental Autoimmune Encephalomyelitis
Investigator(s):Shen J, Chan GCF, Wu W
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Exploring the neuroprotective effect and toxickinetics of An-Gong-Niu-Huang Wan in ischemic rat stroke model
Investigator(s):Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:03/2015


Project Title:Elucidating the role of HMGB1in blood brain barrier disruption and hemorrhage transformation in ischemia-reperfused brain with delayed thrombolytic therapy
Investigator(s):Shen J, Chen X, Chung SK
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2015


List of Research Outputs

Fu S., GU Y., Jiang J.Q., CHEN X., XU M., Chen X. and Shen J., Calycosin-7-O-β-d-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood–brain barrier integrity in experimental cerebral ischemia–reperfusion injury, Journal of Ethnopharmacology. 2014, 155: 692-701.
GU Y., Lee W.S. and Shen J., Site-2 protease responds to oxidative stress and regulates oxidative injury in mammalian cells. , Scientific Reports . 2014, 4:: 6268.
Gao L., Zhou Y., Zhong W., Zhao X., Chen C., Chen X., GU Y., Chen J., Lv Z. and Shen J., Caveolin-1 is essential for protecting against binge drinking-induced liver damage through inhibiting reactive nitrogen species, Hepatology. 2014, 60: 687-699.
Gong J.J., Sun F.M., Li Y.H., Zhou X.L., Duan Z.Z., Duan F.G., ZHAO L., CHEN H., Qi S.H. and Shen J., Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway., Neuropharmacology . 2015, 91: 123-134.
HU J., WONG N.K., YE S., Chen X., LU M., ZHAO Q., GUO Y., Ma C.H., Leung A.Y.H., Shen J. and Yang D., Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In VivoJournal of the American Chemical Society, Journal of the American Chemical Society. 2015, 137: 6837-6843.
Hua Y.Q., Chen Z., Meng Z.Q., Chen H., Shen J., WANG K., Peng W., Shen Y.H. and Liu L.M., High expression of erythropoietin producing hepatoma cell line-B2 (EphB2) predicts the efficiency of the Qingyihuaji formula treatment in pancreatic cancer CFPAC‑1 cells through the EphrinB1‑EphB2 pathway. , Oncology Letters . 2014, 8(1): 17-24.
Peng T., WONG N.K., Chen X., Chan Y.K., Ho H.H., Sun Z., HU J., Shen J., El-Nezamy H.S. and Yang D., Molecular Imaging of Peroxynitrite with HKGreen-4 in Live Cells and Tissues, Journal of the American Chemical Society. 2014, 140724122145003.
Qi Z., Yan F., Shi W., Zhang C., Dong W., Zhao Y., Shen J., Ji X., Liu K.J. and Luo Y.M., AKT-related autophagy contributes to the neuroprotective efficacy of Hydroxysafflor Yellow A against ischemic stroke in rats., Translational Stroke Research 5(4):501-9, 2014. 2014.
Shen J., Big data and drug development: New opportunity for Chinese Medicine. , 2011 Joint Innovation Platform Center Meeting for Native Herbal Medicine. Chengdu Chinese Medical University, March 29-31, 2015, Chengdu, China. 2015.
Shen J., Big data and pharmacological progress of Chinese herbal medicine: New opportunity for network pharmacology, Department of Physiology, University of Toronto, April 30-May 1, 2015, Toronto, Canada. 2015.
Shen J., Big data based approaches for understanding pharmacological principles of Chinese herbal formula and drug discovery., Big Data Symposium, Chinese University of Hong Kong/National Natural Science Foundation of China. September 23-24, 2014, Hong Kong, China. 2014.
Shen J., Current progress of Free Radical Biology in Chinese Medicine and New Drug Development., The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research &The 6th Symposium for Three Districts of Cross-straits on Free Radical Research November 15-16, 2014, Hong Kong, Hong Kong SAR, China . 2014.
Shen J., Development of big data approaches for drug development targeting neurogenesis for post-stroke treatment. , Joint Congress for Professional Committee of Chinese Medicinal Pharmacology, World Federation of Chinese Medicine Societies 2014 &, 20th Sino-Japan Health Science Symposium, December 24-26, 2014, Guangzhou, China. 2014.
Shen J., Molecular Targets of Buyang Huanwu Decoction for Promoting Adult Neurogenesis in Post-ischemic cerebral Injury. Plenary Speaker , 12th Meeting of Consortium for Globalization of Chinese Medicine (CGCM) , Graz, Austria, August 27-29, 2013. 2014.
Shen J., Peroxynitrite could regulate proliferation and neuronal differentiation of neural stem/progenitor cells through activating Wnt/b-catenin signaling pathway. , XXI World Congress of Neurology, Vienna, Austria, September 20-26, 2013. 2014.
Shen J., Reactive nitrogen species are critical targets for blood brain barrier integrity and brain repairs in cerebral ischemia and reperfusion injury. , The First Hospital, Shenzhen University, March 23, 2015, Shenzhen, China.. 2015.
Shen J., Reactive nitrogen species: A crucial molecular targets for drug discovery to treat cerebral ischemia-reperfusion injury, 2013 SFRR-Asia Biennial Meeting, Oxidative Stress and Mitochondrial Alterations in Ageing and Disease, Taipei, Taiwan, October 16-19, 2013. . 2014.
Shen J., Recent trend in Chinese medicine research on stroke rehabilitation., Seminar on Research and Development of Chinese Medicines 2014, Hong Kong Convention and Exhibition Centre, Hong Kong, September 4-5, 2014.
Shen J., Systematic review for toxic metal element contamination and therapeutic components of herbal medicine and herbal pharmaceutical preparations., 8th Conference on Metal Toxicity and Carcinogenesis, October 26-29, 2014, Albuquerque, New Mexico, USA. 2014.
Shen J., The Yin-Yang roles of peroxynitrite in regulating neurotoxicity and neurogenesis: Implication for stroke treatment. Invited speaker, Free Radical Research Special Symposium, Beijing, October 13-14, 2013. 2014.
Sun H., Shen J., Liu T., Tan Y., Tian D., Lai W., Dai M. and Guo Z., Heat shock protein 65 promotes atherosclerosis through impairing the properties of high density lipoprotein, Atherosclerosis . 2014, 237(2): 853-861.
WANG N., Wang Z., Shen J., Peng C., YOU J., PENG F., Guan X. and Chen J., Dietary compound Isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation, Oncotarget. 2015, 6(12): 9854-9876.
WANG N., Wang Z., Cheng P., YOU J., Han S., Shen J. and Chen J., Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via {beta}-catenin/ABCG2 signaling , Carcinogenesis.. 2014.
Zhu W., Zheng G., GU Y., CHEN X., Jin Y., Zhang G., Huang J. and Shen J., Clinical efficacy and sEMG analysis of a new traditional Chinese medicine therapy in the treatment of spasticity following apoplectic hemiparalysis., Acta Neurologica Belgica. 2014, 114(2): 125-129.


Researcher : Shi J

List of Research Outputs

Chen L.Y., Shi J. and Zhang Y., Articles: 中醫藥治療腦退化症的臨床和基礎研究., In: 陳立義,石军,張艷波. , Bamboos (HK), Jan 2015. . 2015, 2015(1): 27.
Lam Y.A.U., Ng T.B., Yiu Y.M., Shi J., Xu K., Zhang Y. and Sze C.W.S., Evaluation of Chemical Constituents and Important Mechanism of Pharmacological Biology in Dendrobium Plants., In: Yau Lam, Tzi Bun Ng, Ren Ming Yao, Jun Shi, Kai Xu, Yanbo Zhang*, Stephen Cho Wing Sze, Evidence-Based Complementary and Alternative Medicine. Volume 2015, Article ID 841752, 25 pages.. 2015, 25:25p.


Researcher : Sze CW

Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS, Zhang Y, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:12/2009


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2010


Project Title:Mechanistic study of iron metabolism in gonadal and extra-gonadal tissues during aging
Investigator(s):Sze CWS, Tong Y, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013


Project Title:Mechanistic study of CAM118, a Chinese Medicine Formula, as an adjuvant therapy for colon cancer and relieving chemotherapy-induced osteoporosis
Investigator(s):Sze CWS, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2014


Project Title:Mechanistic study of iron-dependent ovarian aging in naturally aged Sprague-Dawley rats
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2015


List of Research Outputs

LEIGH A.B., Lai Y.M., Ng T.B., Tong Y. and Sze C.W., Science-based Holistic Philosophy of Chinese Medicine Formula: Reflected in cytotoxicity of Tian-xian Liquid (in vitro) and the protein expression of p21, MMP-1 andMDR-1 in Human Colorectal Carcinoma (in vivo) in Response to Tian-xian Liquid., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
Li P., Zhang Z.M., Li T., Zhang Y., Sze C.W., Wang G.C., Li Y.L. and Ye W.C., Monoterpene derivatives from the roots of Paeonia lactiflora and their anti-proliferative activity, Fitoterapia. 2014, 98c: 124-129.
Liu J., Petersen N.J., Lee C.K.F., Hansen S.H., Lao L., Sze C.W. and Zhang Y., Application of temperature-correlated mobility theory for optimizing the MEKC separation of the main lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoction, Electrophoresis. 2014.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof., European Patent Office. EP 2750684 A1, 2014.
Sze C.W., LU J., Lai Y.M., WONG K.L., Lao L., LEIGH A.B., ZHANG L., Zhang Y. and Ng T.B., The Magic of Chinese Yam, ITC InnoCarnival 2013. 2014.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., 从山药分离出的新颖生物活性蛋白及其用途, 中華人民共和國國家知 識產權局, CN103945854 A, 2014.
WANG S., Ng T.B., Lao L. and Sze C.W., Combing Network Phytochemistry with Networking Pharmacology Approaches to Elucidate the Action Mechanism of Traditional Chinese Medicine Formula: Chemical Constitutes of Erxian Decoction Up-Regulated Estrogen Receptor Expression and Induced Estradiol-Biosynthesis for Menopause as a Study Model., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
WONG K.L., Wong R.N., ZHANG L., Liu W.K., Ng T.B., Shaw P.C., Kwok P.C.L., Lai Y.M., Zhang Z., Zhang Y., Tong Y., CHEUNG H.P., LU J. and Sze C.W., Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential., Chinese medicine. 2014, 9: 19.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.


Researcher : Sze CWS

Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS, Zhang Y, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Support Programme (Tier 2)
Start Date:12/2009


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:02/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:07/2010


Project Title:A Novel Estrogenic Protein from Edible Chinese Yam (Dioscorea Opposita Thunb.) as a Potential Drug Candidate for Relieving Menopausal Syndrome
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Innovation and Technology Fund Internship Programme
Start Date:09/2010


Project Title:Mechanistic study of iron metabolism in gonadal and extra-gonadal tissues during aging
Investigator(s):Sze CWS, Tong Y, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2013


Project Title:Mechanistic study of CAM118, a Chinese Medicine Formula, as an adjuvant therapy for colon cancer and relieving chemotherapy-induced osteoporosis
Investigator(s):Sze CWS, Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2014


Project Title:Mechanistic study of iron-dependent ovarian aging in naturally aged Sprague-Dawley rats
Investigator(s):Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2015


List of Research Outputs

Cheung T.S., SONG T., Ng T.B., Wu F.H., Lao L., Tang S.C.W., Ho J.C.M., Zhang Y. and Sze C.W.S., Therapeutic Effects of Herbal Chemicals in Traditional Chinese Medicine on Alzheimer's Disease, Curr Med Chem . 2015, 22: 2392-2403.
LEIGH A.B., Lai Y.M., Zhang Y., Lao L. and Sze C.W.S., Comparison of effectiveness between CAM118 granules and granule mixtures of its individual herbs at different temperatures on human colon carcinoma HT-29 cells , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
LEIGH A.B., Lai Y.M., Ng T.B., Tong Y. and Sze C.W.S., Science-based Holistic Philosophy of Chinese Medicine Formula: Reflecting in cytotoxicity (in vitro) and the protein expression of p21, MMP-1 and MDR-1 (in vivo) of Tian-xian Liquid in Human Colorectal Carcinoma , 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
LIN X., LIU J., Chung W.Y., Sze C.W.S., Li H.Y., Lao L. and Zhang Y., Polysaccharides of Dendrobium officinale induce aquaporin 5 translocation by activating M3 muscarinic receptors, Planta Med . 2015, 81: 130-137.
LIU J., Sze C.W.S., Lee C.K.F. and Zhang Y., Abstract and poster presentation: Aquaporin9 is a promising novel biomarker and therapeutic target for Alzheimer's disease. , In: Liu JY, Sze CW, Lee KF. Zhang YB*., Cell Symposia: Translational Neuroscience 2014. Nov 13-14, 2014. Arlington, VA, USA. Organization by the editors of Cell Press's leading journals. 2014.11.13-14. . 2014, P2.39.
LIU J., CHEN X., Tang S.C.W., Lao L., Sze C.W.S., Lee C.K.F. and Zhang Y., Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy, In: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Yanbo Zhang, Journal of Functional Foods [IF 4.48]. 2015, 14(2015): 12-22.
LIU J., Tang S.C.W., Sze C.W.S., Lao L., Ho J.C.M., Lee C.K.F. and Zhang Y., Paper and poster presentation: Traditional Chinese Medicine is a Promising Alternative for the Management of Diabetic Nephropathy. , In: Liu JY, Tang SCW, Sze SCW, Lao LX, Ho JCM, Lee CKF, Zhang YB*. , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum, The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research 15 -16/11/2014, Hong Kong. Organized by Commission of Free Radical Biology and Medicine, Biophysical Society of China and Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014.11.15-16. . 2014, p-60.
LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, In: Tianhe SONG, Kalin Yanbo ZHANG*. , The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Aug 27-30, 2014. Beijing, China. Organization by China Academy of Chinese Material Science and Institute of Chinese Material Medica, CACMS. Bejing, China. P332. . 2014.
Lam Y.A.U., Ng T.B., Yiu Y.M., Shi J., Xu K., Zhang Y. and Sze C.W.S., Evaluation of Chemical Constituents and Important Mechanism of Pharmacological Biology in Dendrobium Plants., In: Yau Lam, Tzi Bun Ng, Ren Ming Yao, Jun Shi, Kai Xu, Yanbo Zhang*, Stephen Cho Wing Sze, Evidence-Based Complementary and Alternative Medicine. Volume 2015, Article ID 841752, 25 pages.. 2015, 25:25p.
Man K.W.D., Casettari L., Cepsi C., Bonacucina G., Palmieri F., Sze C.W.S., Leung G.P.H., Lam J.K.W. and Kwok P.C.L., Oleanolic acid loaded PEGylated PLA and PLGA nanoparticles with enhanced cytotoxic activity against cancer cells, Molecular Pharmaceutics. 2015, 12: 2112-2125.
SONG T., Sze C.W.S., Ng T.B., Tang S.C.W., Ho J.C.M. and Zhang Y., Session 3 Chairman. Speaking and abstract: Investigation of Effect Mechanisms and Clinical Study of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced COPD. , In: Song TH, Sze CW, Ng TB, Tang CW, Ho CM, Zhang YB*. , Shanghai, China. Co-organized by the Phytochemical Society of Europe and the Phytochemical Society of Asia. Jun 26-29, 2015. . 2015, p-18.
Sze C.W.S., Bioactive Proteins and Peptides Isolated from Chinese Medicines with Pharmaceutical Potentials, The Joint Workshop on “Good Research and Scientific Publishing” & “Clinical Research for Chinese Medicine Globalization”. The workshop is co-organized by BioMed Central, the Beijing University of Chinese Medicine, Guangdong Province TCM Hospital, Hong Kong Baptist University, and International Society for Chinese Medicine, and Institute of Chinese Medical Sciences (University of Macau).. 2014.
Sze C.W.S., Donation for Cancer Research, Personal Donation. 2015.
Sze C.W.S., Donation for Chinese medicine and Cancer Prevention Research, Donation from Morning Sunshine Cancer Charity Association . 2015.
Sze C.W.S., WONG K.L., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof. (publication no. US 2015/0158919), USPTO. 2015.
WANG S., Ng T.B., Lao L. and Sze C.W.S., Combing Network Phytochemistry with Networking Pharmacology Approaches to Elucidate the Action Mechanism of Traditional Chinese Medicine Formula: Chemical Constitutes of Erxian Decoction Up-Regulated Estrogen Receptor Expression and Induced Estradiol-Biosynthesis for Menopause as a Study Model, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
WANG S., CHEUNG H.P., Ng T.B., Lao L., Zhang Y. and Sze C.W.S., Screening and Mechanistic Study of Estradiol-stimulating Fractions Derived from Erxian Decoction in Aged Sprague-Dawley Rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
ZHANG L., Ng T.B., Lao L., Zhang Y., CHEUNG H.P. and Sze C.W.S., Aberrantly up-regulated expression of transferrin and ferritin induces iron overload and thereby ovarian aging in Sprague-Dawley rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W.S., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
Zhang Y., Sze C.W.S., Tang S.C.W., Ho J.C.M., SONG T. and LIU J., Invention of Efficacy on Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation Though Experimental Rats. , In: Zhang YB*, Sze CW, Tang CW, Ho CW, Song TH, Liu JY., China patent office. 2014.


Researcher : TAN HY

List of Research Outputs

Wang L., Wang N., TAN H.Y., Zhang Y. and Feng Y., Protective Effect of a Chinese Medicine Formula He-Ying-Qing-Re Formula on Diabetic Retinopathy, Journal of Ethnopharmacology. 2015.
Wang N., Feng Y., TAN H.Y., CHEUNG F., HONG M., Lao L. and Nagamatsu T., Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma, Journal of Ethnopharmacology. 2015.
Wang N., TAN H.Y. and Feng Y., Suppression of nascent protein synthesis by natural product berberine, 19th World Congress on Advances in Oncology & 17th International symposium on Molecular Medicine. 2014.
Wang X., Feng Y., Wang N., CHEUNG F., TAN H.Y., Zhong S., Li C. and Kobayashi S., Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy, BioMed Research International. 2014, 2014: 1-14.


Researcher : Tang H

List of Research Outputs

Liu X., Tang H., Chen J., Song C., Yang L. and Liu P., MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple-negative breast cancer, Oncotarget. . 2015.
Song C., Liu L., pei X., Liu X., Yang L., Ye F., Chen J., Tang H. and Xie X., miR-200c inhibits breast cancer proliferation by targeting KRAS. , Oncotarget.. 2015.
Yang L., Tang H., Kong Y., Xie X., Chen J., Song C. and Liu X., LGR5 Promotes Breast Cancer Progression and Maintains Stem-Like Cells Through Activation of Wnt/β-Catenin Signaling, stem cells . 2015.


Researcher : Tian D

List of Research Outputs

Tian D. and Hu Z., CYP3A4-mediated pharmacokinetic interactions in cancer therapy., Curr Drug Metab.. 2014, 15(8): 808-17.
Wang W., Tian D., Zheng B., Wang D., Tan Q., Wang C. and Zhang Z., Peony-Glycyrrhiza Decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models, Drug Metab Dispos. 2015, 43(7): 1147-53.


Researcher : To YT

List of Research Outputs

To Y.T. and Li L., A Single Case Study – Acupuncture in the Treatment of Thoracic Outlet Syndrome, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.


Researcher : Tong Y

Project Title:A pilot study of teaching Chinese Medicine Diagnostics with problem-based learning tutorials
Investigator(s):Tong Y, Shen J, Zhong L, Diu CK
Department:School of Chinese Medicine
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:09/2009


Project Title:A pure chemical isolated from cortex phellodendri as a potential drug candidate for treating menopausal syndrome
Investigator(s):Tong Y, Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2011


List of Research Outputs

LEIGH A.B., Lai Y.M., Ng T.B., Tong Y. and Sze C.W., Science-based Holistic Philosophy of Chinese Medicine Formula: Reflected in cytotoxicity of Tian-xian Liquid (in vitro) and the protein expression of p21, MMP-1 andMDR-1 in Human Colorectal Carcinoma (in vivo) in Response to Tian-xian Liquid., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
LEIGH A.B., Lai Y.M., Ng T.B., Tong Y. and Sze C.W.S., Science-based Holistic Philosophy of Chinese Medicine Formula: Reflecting in cytotoxicity (in vitro) and the protein expression of p21, MMP-1 and MDR-1 (in vivo) of Tian-xian Liquid in Human Colorectal Carcinoma , 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof., European Patent Office. EP 2750684 A1, 2014.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., 从山药分离出的新颖生物活性蛋白及其用途, 中華人民共和國國家知 識產權局, CN103945854 A, 2014.
WONG K.L., Wong R.N., ZHANG L., Liu W.K., Ng T.B., Shaw P.C., Kwok P.C.L., Lai Y.M., Zhang Z., Zhang Y., Tong Y., CHEUNG H.P., LU J. and Sze C.W., Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential., Chinese medicine. 2014, 9: 19.


Researcher : WANG N

List of Research Outputs

WANG N., Wang Z., Shen J., Peng C., YOU J., PENG F., Guan X. and Chen J., Dietary compound Isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation, Oncotarget. 2015, 6(12): 9854-9876.
WANG N., Wang Z., Cheng P., YOU J., Han S., Shen J. and Chen J., Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via {beta}-catenin/ABCG2 signaling , Carcinogenesis.. 2014.
Wang L., Wang N., TAN H.Y., Zhang Y. and Feng Y., Protective Effect of a Chinese Medicine Formula He-Ying-Qing-Re Formula on Diabetic Retinopathy, Journal of Ethnopharmacology. 2015.
Wang N., Feng Y., CHEUNG F., Wang X., Zhang Z. and Feng Y., A Chinese Medicine Formula Gegen Qinlian Decoction Suppresses Expansion of Human Renal Carcinoma With Inhibition of Matrix Metalloproteinase-2, Integrative Cancer Therapies. 2014.
Wang N. and Feng Y., Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in State-of-Art, Biomed Res Int.. 2015.
Wang N. and Feng Y., Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in the State of the Art, BioMed Research International. 2015, 2015: 1-14.
Wang N., Feng Y., TAN H.Y., CHEUNG F., HONG M., Lao L. and Nagamatsu T., Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma, Journal of Ethnopharmacology. 2015.
Wang N., TAN H.Y. and Feng Y., Suppression of nascent protein synthesis by natural product berberine, 19th World Congress on Advances in Oncology & 17th International symposium on Molecular Medicine. 2014.
Wang X., Feng Y., Wang N., CHEUNG F., TAN H.Y., Zhong S., Li C. and Kobayashi S., Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy, BioMed Research International. 2014, 2014: 1-14.
Wang Z., WANG N. and Chen J., Caveolin-1 mediates chemoresistance in breast cancer stem cells via β-catenin/ABCG2 signaling pathway, Carcinogenesis. 2014.
Wang Z., WANG N. and Chen J., MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin, Oncotaget. 2014.
Xu B., Wang N., Pan W., Qiu J., Cao P., ZHU M., Feng Y. and Liang G., Synthesis and anti-tumor activity evaluation of Matijin-Su derivatives, Bioorganic Chemistry. 2014, 56: 34-40.


Researcher : WANG S

List of Research Outputs

WANG S., Ng T.B., Lao L. and Sze C.W., Combing Network Phytochemistry with Networking Pharmacology Approaches to Elucidate the Action Mechanism of Traditional Chinese Medicine Formula: Chemical Constitutes of Erxian Decoction Up-Regulated Estrogen Receptor Expression and Induced Estradiol-Biosynthesis for Menopause as a Study Model., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
WANG S., Ng T.B., Lao L. and Sze C.W.S., Combing Network Phytochemistry with Networking Pharmacology Approaches to Elucidate the Action Mechanism of Traditional Chinese Medicine Formula: Chemical Constitutes of Erxian Decoction Up-Regulated Estrogen Receptor Expression and Induced Estradiol-Biosynthesis for Menopause as a Study Model, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
WANG S., CHEUNG H.P., Ng T.B., Lao L., Zhang Y. and Sze C.W.S., Screening and Mechanistic Study of Estradiol-stimulating Fractions Derived from Erxian Decoction in Aged Sprague-Dawley Rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W.S., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.


Researcher : WONG KL

List of Research Outputs

Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof., European Patent Office. EP 2750684 A1, 2014.
Sze C.W., LU J., Lai Y.M., WONG K.L., Lao L., LEIGH A.B., ZHANG L., Zhang Y. and Ng T.B., The Magic of Chinese Yam, ITC InnoCarnival 2013. 2014.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., 从山药分离出的新颖生物活性蛋白及其用途, 中華人民共和國國家知 識產權局, CN103945854 A, 2014.
Sze C.W.S., WONG K.L., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof. (publication no. US 2015/0158919), USPTO. 2015.
WONG K.L., Wong R.N., ZHANG L., Liu W.K., Ng T.B., Shaw P.C., Kwok P.C.L., Lai Y.M., Zhang Z., Zhang Y., Tong Y., CHEUNG H.P., LU J. and Sze C.W., Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential., Chinese medicine. 2014, 9: 19.


Researcher : Wang L

List of Research Outputs

Wang L., Experience on Syndrome-differentiation and Treatment of Children with Atopic Dermatitis, In: PCM OF WFCMS, The 6th International Academic Exchange Conference of Pediatrics . 2014.
Wang L., Wang N., TAN H.Y., Zhang Y. and Feng Y., Protective Effect of a Chinese Medicine Formula He-Ying-Qing-Re Formula on Diabetic Retinopathy, Journal of Ethnopharmacology. 2015.


Researcher : Wang L

List of Research Outputs

Wang L., Experience on Syndrome-differentiation and Treatment of Children with Atopic Dermatitis, In: PCM OF WFCMS, The 6th International Academic Exchange Conference of Pediatrics . 2014.
Wang L., Wang N., TAN H.Y., Zhang Y. and Feng Y., Protective Effect of a Chinese Medicine Formula He-Ying-Qing-Re Formula on Diabetic Retinopathy, Journal of Ethnopharmacology. 2015.


Researcher : Wang MN

Project Title:Establishment of Dual-Bioluminescent In Vivo Imaging of Autophagy in Orthotopical HCC-Implanted Mice Model To Examine the Anti-Tumor Effect of Chinese Medicine
Investigator(s):Wang N, Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:12/2014


Project Title:Inhibition of carcinogenesis by geniposide isolated from Chinese Medicinal herbs
Investigator(s):Wang N, Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2015


List of Research Outputs



Researcher : Wang N

Project Title:Establishment of Dual-Bioluminescent In Vivo Imaging of Autophagy in Orthotopical HCC-Implanted Mice Model To Examine the Anti-Tumor Effect of Chinese Medicine
Investigator(s):Wang N, Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:12/2014


Project Title:Inhibition of carcinogenesis by geniposide isolated from Chinese Medicinal herbs
Investigator(s):Wang N, Feng Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2015


List of Research Outputs

WANG N., Wang Z., Shen J., Peng C., YOU J., PENG F., Guan X. and Chen J., Dietary compound Isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation, Oncotarget. 2015, 6(12): 9854-9876.
WANG N., Wang Z., Cheng P., YOU J., Han S., Shen J. and Chen J., Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via {beta}-catenin/ABCG2 signaling , Carcinogenesis.. 2014.
Wang L., Wang N., TAN H.Y., Zhang Y. and Feng Y., Protective Effect of a Chinese Medicine Formula He-Ying-Qing-Re Formula on Diabetic Retinopathy, Journal of Ethnopharmacology. 2015.
Wang N., Feng Y., CHEUNG F., Wang X., Zhang Z. and Feng Y., A Chinese Medicine Formula Gegen Qinlian Decoction Suppresses Expansion of Human Renal Carcinoma With Inhibition of Matrix Metalloproteinase-2, Integrative Cancer Therapies. 2014.
Wang N. and Feng Y., Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in State-of-Art, Biomed Res Int.. 2015.
Wang N. and Feng Y., Elaborating the Role of Natural Products-Induced Autophagy in Cancer Treatment: Achievements and Artifacts in the State of the Art, BioMed Research International. 2015, 2015: 1-14.
Wang N., Feng Y., TAN H.Y., CHEUNG F., HONG M., Lao L. and Nagamatsu T., Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma, Journal of Ethnopharmacology. 2015.
Wang N., TAN H.Y. and Feng Y., Suppression of nascent protein synthesis by natural product berberine, 19th World Congress on Advances in Oncology & 17th International symposium on Molecular Medicine. 2014.
Wang X., Feng Y., Wang N., CHEUNG F., TAN H.Y., Zhong S., Li C. and Kobayashi S., Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy, BioMed Research International. 2014, 2014: 1-14.
Wang Z., WANG N. and Chen J., Caveolin-1 mediates chemoresistance in breast cancer stem cells via β-catenin/ABCG2 signaling pathway, Carcinogenesis. 2014.
Wang Z., WANG N. and Chen J., MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin, Oncotaget. 2014.
Xu B., Wang N., Pan W., Qiu J., Cao P., ZHU M., Feng Y. and Liang G., Synthesis and anti-tumor activity evaluation of Matijin-Su derivatives, Bioorganic Chemistry. 2014, 56: 34-40.


Researcher : Wang X

List of Research Outputs

Wang N., Feng Y., CHEUNG F., Wang X., Zhang Z. and Feng Y., A Chinese Medicine Formula Gegen Qinlian Decoction Suppresses Expansion of Human Renal Carcinoma With Inhibition of Matrix Metalloproteinase-2, Integrative Cancer Therapies. 2014.
Wang X., Feng Y., Wang N., CHEUNG F., TAN H.Y., Zhong S., Li C. and Kobayashi S., Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy, BioMed Research International. 2014, 2014: 1-14.


Researcher : Wang Z

Project Title:Elucidating Caveolin-1 as a negative regulator for breast cancer glycolysis activity via activating the c-Myc induced energy metabolism reprogramming
Investigator(s):Wang Z, Chen J, Shen J
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:05/2013


List of Research Outputs

Chen J., Wang Z. and Wang D., 雞血藤提取物及其運用和異甘草素的新用途, China Patent. 2014.
WANG N., Wang Z., Shen J., Peng C., YOU J., PENG F., Guan X. and Chen J., Dietary compound Isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation, Oncotarget. 2015, 6(12): 9854-9876.
WANG N., Wang Z., Cheng P., YOU J., Han S., Shen J. and Chen J., Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via {beta}-catenin/ABCG2 signaling , Carcinogenesis.. 2014.
Wang Z., WANG N. and Chen J., Caveolin-1 mediates chemoresistance in breast cancer stem cells via β-catenin/ABCG2 signaling pathway, Carcinogenesis. 2014.
Wang Z., WANG N. and Chen J., MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin, Oncotaget. 2014.


Researcher : Wong VCW

List of Research Outputs

Man M.S.C., HUNG H.B., Ng R., Yu X.C., Cheung H., Fung P.M., Li L.S.W., Leung K.P., Leung K.P., Tsang W.K., Ziea E., Wong V.C.W. and Zhang Z., A pilot controlled trial of a combination of dense cranial electroacupuncture stimulation and body acupuncture for post-stroke depression, In: Tom Rowles, BMC Complementary and Alternative Medicine. London, UK, BioMed Central, 2014, 14: 255.
ZHU L., ZHANG W., Wong V.C.W., Ziea E.R.I.C., LO K.C., CHAN W.C.C., Yau T.O. and Li L., Two Years versus One Year of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinical Efficacy Observation Trial, Evidence-Based Complementary and Alternative Medicine. 2015, 2014: 9.


Researcher : Wu J

Project Title:Anti-cystic hyperplasia of breast herbal medicine research
Investigator(s):Wu J, Chow LWC
Department:School of Chinese Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:05/2001


Project Title:Anti-prostatomegaly herbal medicine research
Investigator(s):Wu J, Leung SYL
Department:School of Chinese Medicine
Source(s) of Funding:Other Funding Scheme
Start Date:06/2001




Researcher : XU M

List of Research Outputs

Fu S., GU Y., Jiang J.Q., CHEN X., XU M., Chen X. and Shen J., Calycosin-7-O-β-d-glucoside regulates nitric oxide /caveolin-1/matrix metalloproteinases pathway and protects blood–brain barrier integrity in experimental cerebral ischemia–reperfusion injury, Journal of Ethnopharmacology. 2014, 155: 692-701.


Researcher : Xu K

List of Research Outputs

Lam Y.A.U., Ng T.B., Yiu Y.M., Shi J., Xu K., Zhang Y. and Sze C.W.S., Evaluation of Chemical Constituents and Important Mechanism of Pharmacological Biology in Dendrobium Plants., In: Yau Lam, Tzi Bun Ng, Ren Ming Yao, Jun Shi, Kai Xu, Yanbo Zhang*, Stephen Cho Wing Sze, Evidence-Based Complementary and Alternative Medicine. Volume 2015, Article ID 841752, 25 pages.. 2015, 25:25p.
Xu K. and Zhang Y., Invited lecture to HKU, In: Xu Kai, Zhang YB, Research Progress of Pharmacology and Toxicology of Chinese Medicines. P. lecturer Xu Kai, SCM, 2015.04.. 2015.


Researcher : YANG C

List of Research Outputs

CHENG Y., YANG C., ZHAO J., Tse H.F. and Rong J., Proteomic identification of calcium-binding chaperone calreticulin as a potential mediator for the neuroprotective and neuritogenic activities of botanical drug amygdalin,, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, August 27 - 29, 2014.
CHENG Y., YANG C., ZHAO J., Tse H.F. and Rong J., Proteomic identification of calcium-binding chaperone calreticulin as a potential mediator for the neuroprotective and neuritogenic activities of fruit-derived glycoside amygdalin, Journal of Nutritional Biochemistry. 2014, 26: 146-54.
YANG C., Li X.C. and Rong J., Amygdalin isolated from Semen Persicae (Tao Ren) extracts induces the expression of follistatin in HepG2 and C2C12 cell lines, Chinese Medicine. 2014, 9: 23.
YANG C. and Rong J., Click chemistry-assisted identification of caffeic acid propargylamide (CAPA)-modified protein Keap1 demonstrates a general mechanism underlying the neuroprotective and neuritogenic activities of o-catechol-bearing natural products, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research, Hong Kong, China, November 15-16, 2014.
ZHAO J., CHENG Y., YANG C., Lau S.A.M., Lao L., Shuai B., Cai J. and Rong J., Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2, Molecular Neurobiology. 2015.
ZHAO J., CHENG Y., Fan W., YANG C., Ye S., Cui W., Wei W., Lao L., Cai J., Han Y.F. and Rong J., Botanical drug puerarin coordinates with nerve growth factor (NGF) in the regulation of neuronal survival and neuritogenesis via activating ERK1/2 and PI3K/Akt signaling pathways in the neurite extension process, CNS Neuroscience & Therapeutics. 2015, 21: 61-7.


Researcher : YOU J

List of Research Outputs

JIA L., YOU J., Zheng X. and Chen J., Exploration and characterization of the Role of Chronic Mild Stress in Promoting Breast Cancer in Transgenic Mice, 世界中醫會, 2014.
WANG N., Wang Z., Shen J., Peng C., YOU J., PENG F., Guan X. and Chen J., Dietary compound Isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation, Oncotarget. 2015, 6(12): 9854-9876.
WANG N., Wang Z., Cheng P., YOU J., Han S., Shen J. and Chen J., Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via {beta}-catenin/ABCG2 signaling , Carcinogenesis.. 2014.


Researcher : Yeung WF

Project Title:A Systemic Review on the Effectiveness of Chinese Herbal Medicine for Depression
Investigator(s):Yeung WF, Chung KF
Department:Psychiatry
Source(s) of Funding:Hospital Authority - General Award
Start Date:02/2013


Project Title:Use of Complementary and Alternative Medicine for Insomnia in Hong Kong
Investigator(s):Yeung WF, Chung KF
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:06/2013
Completion Date:08/2014


Project Title:Validity and Reliability of the Chinese Version of Uterine Fibroid Symptom and Quality of Life (UFS-QOL) Questionnaire in Hong Kong Chinese Population
Investigator(s):Yeung WF, Meng W, Chen H, Lao L, Lin WL, Chung KF
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2015


List of Research Outputs

Chan W.C., Yeung W.F., WONG S.M., Lam L.C.W., Chung K.F., Luk J.K.H., Lee J.S.W. and Law A.C.K., Efficacy of Physical Exercise in Preventing Falls in Older Adults With Cognitive Impairment: A Systematic Review and Meta-Analysis, Journal of the American Medical Directors Association. 2015, 16: 149-154.
HO Y.Y.F., Chung K.F., Yeung W.F., NG H.Y. and Cheng K.W., Internet-based self-help cognitive behavioral therapy for Chinese adults with insomnia disorder: a randomized controlled trial, Behav Res Ther. 2014.
Lam M.Y. and Yeung W.F., 論睡眠衛生與《內經》對失眠之認識, 世界睡眠醫學雜誌, 2014, 1: 239-242.
Lao L. and Yeung W.F., Treating chronic knee pain with acupuncture (Letter to Editor), JAMA. 2015, 313: 627-8.


Researcher : Yiu YM

List of Research Outputs

Lam Y.A.U., Ng T.B., Yiu Y.M., Shi J., Xu K., Zhang Y. and Sze C.W.S., Evaluation of Chemical Constituents and Important Mechanism of Pharmacological Biology in Dendrobium Plants., In: Yau Lam, Tzi Bun Ng, Ren Ming Yao, Jun Shi, Kai Xu, Yanbo Zhang*, Stephen Cho Wing Sze, Evidence-Based Complementary and Alternative Medicine. Volume 2015, Article ID 841752, 25 pages.. 2015, 25:25p.
Yiu Y.M., Acupuncture Combined with Herb Treatment of Infertility: A report of 3 cases, 針藥并用治療不孕症驗案3則, 2015 San Francisco International Symposium on Chinese Medicine . San Francisco, California, California Certified Acupuncturists Association, 2015, 03/2015: 100-102.


Researcher : Yum TP

List of Research Outputs

Yum T.P., LO K.C. and Li L., Literature Review on Acupuncture Sensation in Different Acupoints, The 13th Meeting of The Consortium for Globalization of Chinese Medicine(CGCM). Beijing, China, 2014.
ZHU L., CHAN W.C.C., LO K.C., Yum T.P. and Li L., Wrist-Ankle Acupuncture for the Treatment of Pain Symptoms: A systematic Review and Meta-analysis, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2014, 2014: 9.


Researcher : ZHANG L

List of Research Outputs

LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, In: Tianhe SONG, Kalin Yanbo ZHANG*. , The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Aug 27-30, 2014. Beijing, China. Organization by China Academy of Chinese Material Science and Institute of Chinese Material Medica, CACMS. Bejing, China. P332. . 2014.
Sze C.W., LU J., Lai Y.M., WONG K.L., Lao L., LEIGH A.B., ZHANG L., Zhang Y. and Ng T.B., The Magic of Chinese Yam, ITC InnoCarnival 2013. 2014.
WONG K.L., Wong R.N., ZHANG L., Liu W.K., Ng T.B., Shaw P.C., Kwok P.C.L., Lai Y.M., Zhang Z., Zhang Y., Tong Y., CHEUNG H.P., LU J. and Sze C.W., Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential., Chinese medicine. 2014, 9: 19.
ZHANG L., Ng T.B., Lao L., Zhang Y., CHEUNG H.P. and Sze C.W.S., Aberrantly up-regulated expression of transferrin and ferritin induces iron overload and thereby ovarian aging in Sprague-Dawley rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging., The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, China. 2014.
ZHANG L., CHEUNG H.P., WANG S., Lao L., Ng T.B. and Sze C.W.S., Proteomics Analysis of the effects of Erxian Decoction on Retarding Ovarian Aging, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.


Researcher : ZHANG W

List of Research Outputs

ZHU L., ZHANG W., Wong V.C.W., Ziea E.R.I.C., LO K.C., CHAN W.C.C., Yau T.O. and Li L., Two Years versus One Year of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinical Efficacy Observation Trial, Evidence-Based Complementary and Alternative Medicine. 2015, 2014: 9.


Researcher : ZHAO J

List of Research Outputs

CHENG Y., YANG C., ZHAO J., Tse H.F. and Rong J., Proteomic identification of calcium-binding chaperone calreticulin as a potential mediator for the neuroprotective and neuritogenic activities of botanical drug amygdalin,, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, August 27 - 29, 2014.
CHENG Y., YANG C., ZHAO J., Tse H.F. and Rong J., Proteomic identification of calcium-binding chaperone calreticulin as a potential mediator for the neuroprotective and neuritogenic activities of fruit-derived glycoside amygdalin, Journal of Nutritional Biochemistry. 2014, 26: 146-54.
Shuai B., Yang Y.P., Shen L., Zhu R., Xu X.J., Ma C., Lv L., ZHAO J. and Rong J., Local renin-angiotensin system is associated with bone mineral density of glucocorticoid-induced osteoporosis patients, Osteoporosis International. 2015, 26: 1063-1071.
ZHAO J., Han Y. and Rong J., Botanical C-glucosylated isoflavone puerarin suppresses nitric oxide-induced neurotoxicity via inducing arginase-2 expression, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Beijing, August 27 - 29, 2014.
ZHAO J., CHENG Y., YANG C., Lau S.A.M., Lao L., Shuai B., Cai J. and Rong J., Botanical Drug Puerarin Attenuates 6-Hydroxydopamine (6-OHDA)-Induced Neurotoxicity via Upregulating Mitochondrial Enzyme Arginase-2, Molecular Neurobiology. 2015.
ZHAO J., CHENG Y., Fan W., YANG C., Ye S., Cui W., Wei W., Lao L., Cai J., Han Y.F. and Rong J., Botanical drug puerarin coordinates with nerve growth factor (NGF) in the regulation of neuronal survival and neuritogenesis via activating ERK1/2 and PI3K/Akt signaling pathways in the neurite extension process, CNS Neuroscience & Therapeutics. 2015, 21: 61-7.
ZHAO J. and Rong J., Pharmacological Induction of Arginase II by C-glucosylated Isoflavonone Puerarin Suppresses Nitric Oxide-induced Mitochondrial Dysfunction in Differentiated Neuronal PC12 Cells, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research, Hong Kong, China, November 15-16, 2014.
ZHAO J. and Rong J., Pharmacological induction of arginase II by C-glucosylated isoflavonone puerarin suppresses nitric oxide-induced mitochondrial dysfunction in differentiated neuronal PC12 cells, Experimental Biology 2015, Boston, MA, USA, March 28-April 1, 2015.. 2015.
ZHAO J., Lao L. and Rong J., Plant natural product puerarin suppressed 6-hydroxydopamine (6-OHDA)-induced neurotoxicity via inducing mitochondrial enzyme arginase-2, the XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and the XIIth International Conference on Quantification of Brain Function with PET, Vancouver, British Columbia, June 27-30, 2015.


Researcher : ZHAO L

List of Research Outputs

Gong J.J., Sun F.M., Li Y.H., Zhou X.L., Duan Z.Z., Duan F.G., ZHAO L., CHEN H., Qi S.H. and Shen J., Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway., Neuropharmacology . 2015, 91: 123-134.


Researcher : ZHU L

List of Research Outputs

ZHU L., LO K.C. and Li L., Review of Clinical Research for Tian Jiu Therapy on Asthma, China Journal of Chinese Medicine. 2015, (6): 34-37.
ZHU L., LO K.C. and Li L., The Analysis of Factors Influencing Tian Jiu Therapy on Asthma, Guangming Journal of Chinese Medicine. 2014, (8): 1794-1796.
ZHU L., ZHANG W., Wong V.C.W., Ziea E.R.I.C., LO K.C., CHAN W.C.C., Yau T.O. and Li L., Two Years versus One Year of Tianjiu Therapy in Sanfu Days for Chronic Asthma: A Clinical Efficacy Observation Trial, Evidence-Based Complementary and Alternative Medicine. 2015, 2014: 9.
ZHU L., CHAN W.C.C., LO K.C., Yum T.P. and Li L., Wrist-Ankle Acupuncture for the Treatment of Pain Symptoms: A systematic Review and Meta-analysis, Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation, 2014, 2014: 9.


Researcher : ZHU M

List of Research Outputs

Xu B., Wang N., Pan W., Qiu J., Cao P., ZHU M., Feng Y. and Liang G., Synthesis and anti-tumor activity evaluation of Matijin-Su derivatives, Bioorganic Chemistry. 2014, 56: 34-40.


Researcher : Zhang Y

Project Title:Evidencing effect of RHY in regulation of aquaporin-9 expression from damaged astrocytes closely associated with Alzheimer’s disease
Investigator(s):Zhang Y, Sze CWS, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


Project Title:International Symposium on Phytochemicals in Medicine and Food (ISPMF 2015); Investigation of Effect Mechanisms and Clinical Study of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced COPD
Investigator(s):Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2015


Project Title:Development of a nanoparticle based diagnostic platform for screening active ingredients from Traditional Chinese Medicine extracts
Investigator(s):Zhang Y
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2015


List of Research Outputs

Chan Y.S., Zhang Y. and Ng T.B., A thermostable trypsin inhibitor with antiproliferative activity from small pinto beans. , In: Chan YS, Zhang Y, Sze SC, Ng TB., J Enzyme Inhib Med Chem. 2014 Aug; 29(4): 485-90. . 2014, 29(4): 485-90.
Chen L.Y., Shi J. and Zhang Y., Articles: 中醫藥治療腦退化症的臨床和基礎研究., In: 陳立義,石军,張艷波. , Bamboos (HK), Jan 2015. . 2015, 2015(1): 27.
Cheung T.S., SONG T., Ng T.B., Wu F.H., Lao L., Tang S.C.W., Ho J.C.M., Zhang Y. and Sze C.W.S., Therapeutic Effects of Herbal Chemicals in Traditional Chinese Medicine on Alzheimer's Disease, Curr Med Chem . 2015, 22: 2392-2403.
LEIGH A.B., Lai Y.M., Zhang Y., Lao L. and Sze C.W.S., Comparison of effectiveness between CAM118 granules and granule mixtures of its individual herbs at different temperatures on human colon carcinoma HT-29 cells , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
LIN X., LIU J., Chung W.Y., Sze C.W.S., Li H.Y., Lao L. and Zhang Y., Polysaccharides of Dendrobium officinale induce aquaporin 5 translocation by activating M3 muscarinic receptors, Planta Med . 2015, 81: 130-137.
LIU J., Sze C.W.S., Lee C.K.F. and Zhang Y., Abstract and poster presentation: Aquaporin9 is a promising novel biomarker and therapeutic target for Alzheimer's disease. , In: Liu JY, Sze CW, Lee KF. Zhang YB*., Cell Symposia: Translational Neuroscience 2014. Nov 13-14, 2014. Arlington, VA, USA. Organization by the editors of Cell Press's leading journals. 2014.11.13-14. . 2014, P2.39.
LIU J., CHEN X., Tang S.C.W., Lao L., Sze C.W.S., Lee C.K.F. and Zhang Y., Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy, In: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Yanbo Zhang, Journal of Functional Foods [IF 4.48]. 2015, 14(2015): 12-22.
LIU J., Tang S.C.W., Sze C.W.S., Lao L., Ho J.C.M., Lee C.K.F. and Zhang Y., Paper and poster presentation: Traditional Chinese Medicine is a Promising Alternative for the Management of Diabetic Nephropathy. , In: Liu JY, Tang SCW, Sze SCW, Lao LX, Ho JCM, Lee CKF, Zhang YB*. , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum, The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research 15 -16/11/2014, Hong Kong. Organized by Commission of Free Radical Biology and Medicine, Biophysical Society of China and Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014.11.15-16. . 2014, p-60.
LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Beijing, 2014.
LU J., Wong R.N.S., ZHANG L., Lao L., Zhang Y., Ng T.B. and Sze C.W.S., Comparative analysis of estradiol-stimulating proteins from four different Dioscorea species, In: Tianhe SONG, Kalin Yanbo ZHANG*. , The 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM), Aug 27-30, 2014. Beijing, China. Organization by China Academy of Chinese Material Science and Institute of Chinese Material Medica, CACMS. Bejing, China. P332. . 2014.
Lam C.H. and Zhang Y., Invited lecture, In: Lam CH, Zhang YB, background of manager and develop in Chinese medicine-II. (Dr Lam CH, HA, HK government, 2015.01). 2015.
Lam J.K.W. and Zhang Y., invited lecture to HKU, In: Jenny K.W. LAM, Sze CW, Zhang YB. , modern development and trade of Chinese medicines-I. Dr. Jenny K.W. LAM, Pharmaceutical & Phamacy, LKS Faculty of Medicine, 2015.01.. 2015.
Lam Y.A.U., Ng T.B., Yiu Y.M., Shi J., Xu K., Zhang Y. and Sze C.W.S., Evaluation of Chemical Constituents and Important Mechanism of Pharmacological Biology in Dendrobium Plants., In: Yau Lam, Tzi Bun Ng, Ren Ming Yao, Jun Shi, Kai Xu, Yanbo Zhang*, Stephen Cho Wing Sze, Evidence-Based Complementary and Alternative Medicine. Volume 2015, Article ID 841752, 25 pages.. 2015, 25:25p.
Leung G.P.H. and Zhang Y., Invited lecture to HKU, In: Leung PH, Zhang YB, western drug development and direction. Dr Leung PH, Pharmaceutical & Phamacy, LKS Faculty of Medicine, 2014.10. . 2014.
Li P., Zhang Z.M., Li T., Zhang Y., Sze C.W., Wang G.C., Li Y.L. and Ye W.C., Monoterpene derivatives from the roots of Paeonia lactiflora and their anti-proliferative activity, Fitoterapia. 2014, 98c: 124-129.
Lin G. and Zhang Y., Invited lecture to HKU, In: Lin Ge, Zhang YB, quality analysis study in Chinese medicines-I. Prof Lin Ge, CUHK, 2014.12. . 2014.
Lin G. and Zhang Y., Lectures, In: Lin G, Zhang Yanbo , quality analysis study in Chinese medicines-I (Prof Lin Ge, School of Biomedical Science, CUHK. 11/2014). 2014.
Lin X.I.A.N.G., Liu J.I.N.G.Y.I., Chung W.I.N.G.Y.A.N., Li H.A.N.Y.A.N., Lao L. and Zhang Y., Polysaccharides of Dendrobium officinale Induce AQP-5 Translocation by Activating M3 Muscarinic Receptor, In: Xiang Lin, Jingyi Liu, Wingyan Chung, Stephen Cho-Wing Sze, Haiyan Li, Lixing Lao, Yanbo Zhang, Planta Medica . 2015, 2(81):130-137.
Liu J., Petersen N.J., Lee C.K.F., Hansen S.H., Lao L., Sze C.W. and Zhang Y., Application of temperature-correlated mobility theory for optimizing the MEKC separation of the main lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoction, Electrophoresis. 2014.
SONG T. and Zhang Y., Abstract and poster presentation: Enhanced antitumor effect of dendrobine combined with cisplatin for treating non-small cell lung cancer. , In: Song TH, Zhang KYB*. , Conference in Translation of the Cancer Genome. February 7-9, 2015, Fairmont San Francisco, San Francisco, California. Organization by American Association for Cancer Research. 2015.02.07-09. . 2015, A2-69.
SONG T. and Zhang Y., Abstract and poster presentation: Investigation on the anti-inflammatory activity and mechanism of Dendrobium extract in vitro and in vivo. P332. , In: Song TH, Zhang YB* , 13th Meeting of Consortium for Globalization of Chinese Medicine (CGCM). Organizer by China Academy of Chinese Medical Sciences. International Conference Centre. Bejing, China. 2014.08.27-30.. 2014, p332.
SONG T., Sze C.W.S., Ng T.B., Tang S.C.W., Ho J.C.M. and Zhang Y., Session 3 Chairman. Speaking and abstract: Investigation of Effect Mechanisms and Clinical Study of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced COPD. , In: Song TH, Sze CW, Ng TB, Tang CW, Ho CM, Zhang YB*. , Shanghai, China. Co-organized by the Phytochemical Society of Europe and the Phytochemical Society of Asia. Jun 26-29, 2015. . 2015, p-18.
Shao R. and Zhang Y., Invited lecture to HKU, In: Shao R, Zhang Yanbo, Lecture in modern development and trade of Chinese medicine-I. (Prof Shao Rong, China Pharmaceutical University, 12/2014). 2014.
Shaw P.C. and Zhang Y., Lectures, In: Shaw PC, Zhang Yanbo, quality analysis study in Chinese medicines-II (Prof Shaw PC, School of Life Science, CUHK. 11/2014) . 2014.
Shaw P.C. and Zhang Y., invited lecture to HKU, In: Shaw PC, Zhang YB. , quality analysis study in Chinese medicines-II. Prof Shaw PC, CUHK, 2015.01.. 2015.
Sun L.H. and Zhang Y., Invited lecture in HKU, In: Sun LH, modern development and trade of Chinese medicine-II. (Prof Sun LH, Shenyang Pharmaceutical University, 12/2014). 2014.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof., European Patent Office. EP 2750684 A1, 2014.
Sze C.W., LU J., Lai Y.M., WONG K.L., Lao L., LEIGH A.B., ZHANG L., Zhang Y. and Ng T.B., The Magic of Chinese Yam, ITC InnoCarnival 2013. 2014.
Sze C.W., WONG K.L., Tong Y., Zhang Y. and CHEUNG H.P., 从山药分离出的新颖生物活性蛋白及其用途, 中華人民共和國國家知 識產權局, CN103945854 A, 2014.
Sze C.W.S., WONG K.L., Zhang Y. and CHEUNG H.P., Novel Bioactive Protein Isolated from Chinese Yam and uses thereof. (publication no. US 2015/0158919), USPTO. 2015.
Tang M.H. and Zhang Y., invited lecture to HKU, In: Tang MH, Zhang YB, R&D and registration of Chinese medicine. Dr Tang MH, Bright Future Pharmaceutical Laboratories Ltd (HK), 2015.04. . 2015.
WANG S., CHEUNG H.P., Ng T.B., Lao L., Zhang Y. and Sze C.W.S., Screening and Mechanistic Study of Estradiol-stimulating Fractions Derived from Erxian Decoction in Aged Sprague-Dawley Rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
WONG K.L., Wong R.N., ZHANG L., Liu W.K., Ng T.B., Shaw P.C., Kwok P.C.L., Lai Y.M., Zhang Z., Zhang Y., Tong Y., CHEUNG H.P., LU J. and Sze C.W., Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential., Chinese medicine. 2014, 9: 19.
Xu K. and Zhang Y., Invited lecture to HKU, In: Xu Kai, Zhang YB, Research Progress of Pharmacology and Toxicology of Chinese Medicines. P. lecturer Xu Kai, SCM, 2015.04.. 2015.
ZHANG L., Ng T.B., Lao L., Zhang Y., CHEUNG H.P. and Sze C.W.S., Aberrantly up-regulated expression of transferrin and ferritin induces iron overload and thereby ovarian aging in Sprague-Dawley rats, The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research . Hong Kong, 2014.
Zhang Y., Sze C.W.S., Tang S.C.W., Ho J.C.M., SONG T. and LIU J., Invention of Efficacy on Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced Pulmonary Inflammation Though Experimental Rats. , In: Zhang YB*, Sze CW, Tang CW, Ho CW, Song TH, Liu JY., China patent office. 2014.
Zhang Y., Invited lecture, In: Zhang Yanbo, Scientific validation of Chinese medicines. Advancement on Pharmacology research of Chinese medicine. Hong Kong Central Library. Public Lecture Series 2015 - May (2015-05-09) . 2015.
Zhang Y., PI: D-research on the safety and quality control of clinical Chinese medicine compounds., In: Zhang Yanbo, Donation funding from HK company ALAGATE group LTD. HKU account No. 200007377.07/10/2014. 2015.
Zhang Y., PI: Development of a nanoparticle based diagnostic platform for screening active ingredients from Traditional Chinese Medicine extracts., In: Zhang Yanbo, Small Project Funding from HKU. Project No. 201409176059. 25/02/2015. 2015.
Zhang Y., PI: Evidencing effect of RHY in regulation of aquaporin-9 expression from damaged astrocytes closely associated with Alzheimer’s disease. , In: Zhang Yanbo, Seed Funding Programme for Basic Research from HKU. Award: 14/05/2014. Project No.201311159022. . 2015.
Zhang Y., PI: Investigation of Effect Mechanisms and Clinical Study of Polysaccharide of Dendrobium officinale in Alleviating Cigarette-Induced COPD. , In: Zhang Yanbo, URC/CRCG - Conference Support for Teaching Staff. 09/06/2015. Project No. 201407170563. . 2015, P18.
Zhang Y., international journal editor, In: Zhang Yanbo, Pharmacologia. Jul 1, 2014-present. 2014.


Researcher : Zhang Z

Project Title:The Establishment of Neurobehavioral Experiments into the Acupuncture Course (BCHM3003, 針灸學) of Undergraduate Chinese Medicine Programs
Investigator(s):Zhang Z, Tong Y
Department:School of Chinese Medicine
Source(s) of Funding:Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants
Start Date:07/2007


Project Title:The development of a clinical-case search system to introduce case-study learning mode into Chinese medical curricula
Investigator(s):Zhang Z, Wong HK
Department:School of Chinese Medicine
Source(s) of Funding:Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants
Start Date:09/2008


Project Title:The identification of central neural network for antidepressant effects of dense cranial electroacupuncture stimulation - a positron emission topographic (PET) study
Investigator(s):Zhang Z, Chung KF, Cowling BJ, Law ACK, Wong CS
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:The herbal medicine Peony-Glycyrrhiza Decoction (PGD) as an adjunctive therapy to treat antipsychotic-induced hyperprolactinemia in female patients with schizophrenia: a double-blind, randomized, placebo-controlled study
Investigator(s):Zhang Z, Chen EYH
Department:School of Chinese Medicine
Source(s) of Funding:Health and Health Services Research Fund - Full Grants
Start Date:02/2012


Project Title:Does concomitant use with Chinese medicines alter pharmacokinetic and toxicological profiles of antipsychotic drugs in experimental rats? Implication for herb-drug interactions
Investigator(s):Zhang Z, Sze CWS
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013


Project Title:The identification of psychopharmacological mechanisms of glycyrrhetinic acid in reducing antipsychotic-induced hyperprolactinemia
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Acupuncture prevents chemobrain in patients with breast cancer: is it associated with the protection against cytokine production, epigenetic modification and microstructural changes of the brain?
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


Project Title:A novel therapeutic equipement called Acupoint-based Cranial Electromechanical Stimulator (ACEMS) for stress-associated symptoms
Investigator(s):Zhang Z, Hu Y
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Applied Research
Start Date:06/2014
Completion Date:06/2015


Project Title:Serotonin type 3 (5-HT3) receptor antagonists protect against traumatic brain injury
Investigator(s):Zhang Z
Department:School of Chinese Medicine
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2015


List of Research Outputs

Hsu W.W.Q., Chan E.W., Zhang Z., Lin Z.X., Bian Z.X., Hsia Y. and Wong I.C.K., A survey to investigate attitudes and perceptions of Chinese medicine professionals in health information technology in Hong Kong, Eur J Integr Med. 2015, 7(1): 36-46.
Hsu W.W.Q., Chan E.W., Zhang Z., Lin Z.X., Bian Z.X. and Wong I.C.K., Chinese medicine students’ view on electronic prescribing: A survey in Hong Kong, Eur J Integr Med. 2015, 7(1): 47-54.
Man M.S.C., HUNG H.B., Ng R., Yu X.C., Cheung H., Fung P.M., Li L.S.W., Leung K.P., Leung K.P., Tsang W.K., Ziea E., Wong V.C.W. and Zhang Z., A pilot controlled trial of a combination of dense cranial electroacupuncture stimulation and body acupuncture for post-stroke depression, In: Tom Rowles, BMC Complementary and Alternative Medicine. London, UK, BioMed Central, 2014, 14: 255.
Qu L.F., Zhang W.H., Zhang Z., Shi Y., Cai J. and Chai K.F., Mental Diseases in Traditional Chinese Medicine. 中医神志病学, Shanghai Publish House of Sciences and Technology, 2015.
WONG K.L., Wong R.N., ZHANG L., Liu W.K., Ng T.B., Shaw P.C., Kwok P.C.L., Lai Y.M., Zhang Z., Zhang Y., Tong Y., CHEUNG H.P., LU J. and Sze C.W., Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential., Chinese medicine. 2014, 9: 19.
Wang N., Feng Y., CHEUNG F., Wang X., Zhang Z. and Feng Y., A Chinese Medicine Formula Gegen Qinlian Decoction Suppresses Expansion of Human Renal Carcinoma With Inhibition of Matrix Metalloproteinase-2, Integrative Cancer Therapies. 2014.
Wang W., Tian D., Zheng B., Wang D., Tan Q., Wang C. and Zhang Z., Peony-Glycyrrhiza Decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models, Drug Metab Dispos. 2015, 43(7): 1147-53.
Wang X.M.A., Walitt B., Saligan L., Tiwari A.F.Y., Cheung C.W. and Zhang Z., Chemobrain: a critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy, Cytokine. 2015, 72(1): 86-96.
Zhang Z. and Chen H., Manic Psychosis, 狂病, Chinese MedicineTextbook of Psychiatry. 中醫神誌病學(供中醫類專業用), Shanghai, Shanghai Scientific & Technical Publishers, 2015, 273-278.
Zhang Z. and Chen H., Obsessive-compulsive Disorder, 強迫症, Chinese MedicineTextbook of Psychiatry. 中醫神誌病學(供中醫類專業用), Shanghai, Shanghai Scientific & Technical Publishers, 2015, 70-75.
Zheng Y., Zhang Z., Han X.M., Ding Y., Chen Y.Y., Wang X.F., Wei X.W., Wang M.J., Cheng Y., Nie Z.H., Zhao M. and Zheng X.X., A proprietary herbal medicine (5-Ling Granule) for Tourette syndrome: a randomized controlled trial, Journal of Child Psychology and Psychiatry. 2015, n/a-n/a.


Researcher : Zhu W

List of Research Outputs

Zhu W., Zheng G., GU Y., CHEN X., Jin Y., Zhang G., Huang J. and Shen J., Clinical efficacy and sEMG analysis of a new traditional Chinese medicine therapy in the treatment of spasticity following apoplectic hemiparalysis., Acta Neurologica Belgica. 2014, 114(2): 125-129.


-- End of Listing --