DEPT OF OBSTETRICS & GYNAECOLOGY



Researcher : CAI C

List of Research Outputs

CAI C., Shi L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling , 2014.
CAI C., SHI L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling, Oncotarget. USA, Impact Journals, LLC., 2014, 5: 7549-62.


Researcher : CAO M

List of Research Outputs

CAO M., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Label Retaining Stromal Cells Are Involved in Uterine Remodeling after Parturition., World Congress of Reproductive Biology. 2014.


Researcher : CHEN CH

List of Research Outputs

CHEN C.H., Lee C.Y.L., Fong S.W. and Yeung W.S.B., Hyperglycemia impedes hESC differentiation into definitive endoderm through modulation of histone methylation patterns, International Society of Stem Cell Research 2015.
Lee C.Y.L., Fong S.W., CHEN C.H., LI T., Yeung W.S.B. and Lee C.K.F., A NOVEL HUMAN EMBRYONIC STEM CELL-DERIVED TROPHOBLASTIC SPHEROID IMPLANTATION MODEL FOR THE STUDY OF EARLY HUMAN IMPLANTATION, International Society Of Stem Cells Research Annual Meeting 2015.


Researcher : Chai J

Project Title:10th RCOG International Scientific Congress A randomized clinical trial comparing the sublingual and buccal routes of administration of misoprostol after mifepristone for medical abortions of up to 63 days gestation
Investigator(s):Chai J
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2012


List of Research Outputs

Chai J., Howie A.F., Cameron D.A. and Anderson R.A., A highly-sensitive anti-Mullerian hormone assay improves analysis of ovarian function following chemotherapy for early breast cancer, ESHRE 2014.
Chai J., Howie A.F., Cameron D.A. and Anderson R.A., A highly-sensitive anti-Mullerian hormone assay omroves analysis of ovarian function following chemotherapy for early breast cancer, Eur J Cancer. 2014, 29(11): 2474-2481.
Chai J., Lee V.C., Yeung T.W., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment, PLoS One. 2015, 10(3).
Yeung T.W., Chai J., Li R.H.W., Lee V.C., Ho P.C. and Ng E.H.Y., The effect of endometrial injury on ongoing pregnancy rate in unselected subfertile women undergoing in vitro fertilization: a randomized controlled trial, Human Reproduction. 2014, 29: 2474-2481.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders, Fertility and Sterility. 2014, 102: 108-115.e1.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Reply: Endometrial injury and reproductive outcomes: there's more to this story than meets the horse's blind eye, Human Reproduction. 2015, 3: 749-750.


Researcher : Chan DW

Project Title:The functional impact of AMP-activated protein kinase gamma-2 (AMPK-g2)subunit expression on AMPK activity and oncogenesis in ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:12/2011


Project Title:Mechanistic and functional characterization of Bitter Melon extract (BME) and its active component, MAP30, in combating ovarian cancer chemoresistance
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013


Project Title:Functional significance of TAK1-mediated NFkB signaling in omental metastasis of ovarian cancer
Investigator(s):Chan DW, Yam JWP, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


Project Title:Identification putative genetic or epigenetic candidate genes associated with omental metastasis of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2014


Project Title:The mechanism and significance of ovarian cancer cells in modulating AMPK and TNFkB signaling cascade in omental metastasis
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2015


Project Title:Identification of BCL2A1 as a novel stress-inducible factor in metastatic progression of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2015


Project Title:Cold Spring Harbor Asia conference on Precision Cancer Biology and Medicine; Role of Has-miR-141 as a therapeutic target and predictive biomarker for ovarian cancer
Investigator(s):Chan DW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2015


List of Research Outputs

CAI C., Shi L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling , 2014.
CAI C., SHI L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling, Oncotarget. USA, Impact Journals, LLC., 2014, 5: 7549-62.
Chan D.W., Editorial Board Member, Journal of Cancer Metastasis and Treatment. 2014.
Chan D.W., Editorial Board Member, PLoS One. San Francisco, CA, USA, plos.org, 2014.
Chan D.W., Honor Certificate, 榮譽證書: 國家級科技項目獎先進個人 , Shenzhen Science Technology Institute. 深圳市科技創新委員會, 2014.
Chan D.W., MAK S.L. and Ngan H.Y.S., MiR-141 not only modulates anoikis resistance of ovarian cancer cells but also alters pre-metastatic niche for ovarian cancer cell metastatic colonization, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic. Florence of Italy, from June 20th to 23rd,2015.
Chan D.W., MAK S.L. and Ngan H.Y.S., Role of Has-miR-141 as a therapeutic target and predictive biomarker for ovarian cancer, Cold Spring Harbour Asia-Precision Cancer Biology and Medicine. 2015.
Chan D.W., Targeting AMPK as a valid therapeutic intervention in ovarian cancer, 21st Hong Kong International Cancer Congress. 2014.
LIANG R., Ngan H.Y.S. and Chan D.W., BCL2A1 Plays a Biphasic Role in Ovarian Cancer Progression, 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.
LIU J., Ngan H.Y.S. and Chan D.W., Identification of cisplatin-resistance related genes in Ovarian clear cell carcinoma using 3D cell culture model., 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.
LIU J., Ngan H.Y.S. and Chan D.W., Identification of cisplatin-resistance related genes in ovarian clear cell carcinoma using 3D cell culture system, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic held in Florence of Italy, from June 20th to 23rd, 2015.
TANG W.M., Ngan H.Y.S. and Chan D.W., The chemokines GRO-α and IL-8 secreted form omentum promotes aggressiveness of ovarian cancer cells, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic held in Florence of Italy, from June 20th to 23rd, 2015.. 2015.
TANG W.M., Ngan H.Y.S. and Chan D.W., The significance of Gro-α in modulating omental metastasis of ovarian cancer cells, 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.


Researcher : Chan KKL

Project Title:Relationship between placental ratio and placental function
Investigator(s):Chan KKL, Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding for New Staff
Start Date:01/2003


Project Title:The effect of fulvestrant in epithelial ovarian cancer with differential estrogen receptor status in mice
Investigator(s):Chan KKL, Liu S, Tam KF, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2008


Project Title:Sixth International Symposium on Hormonal Oncogenesis USE OF HIGHLY SELECTIVE ESTROGEN RECEPTOR MODULATORS IN OVARIAN CANCER
Investigator(s):Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2010


Project Title:Characterization of the Platelet Isoform of Phosphofructokinase (PFKP) in ovarian cancer
Investigator(s):Chan KKL, Siu KY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013


Project Title:Differential roles of estrogen receptor subtypes and variants in ovarian cancer: implications for personalized hormonal treatment.
Investigator(s):Chan KKL, Leung THY, Ngan HYS, Siu KY, Cheung ANY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


Project Title:Unraveling the role of pyruvate dehydrogenase kinase 1 (PDK1) in ovarian cancer chemoresistance
Investigator(s):Chan KKL, Ngan HYS, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2014


Project Title:Role of pyruvate dehydrogenase kinase 1 (PDK1) in tumorigenesis and metastasis of ovarian cancer
Investigator(s):Chan KKL, Ngan HYS, Cheung ANY, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2014


Project Title:Characterization of PFKFB3 in ovarian cancer
Investigator(s):Chan KKL, Ngan HYS, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2015


List of Research Outputs

CAI C., Shi L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling , 2014.
CAI C., SHI L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling, Oncotarget. USA, Impact Journals, LLC., 2014, 5: 7549-62.
Chan K.K.L., Editorial Board, Journal of Paediatrics, Obstetrics and Gynaecology. 2015.
Chan K.K.L., Low Risk Gestational Trophoblastic Neoplasia, 15th Biennial Meeting of International Gynecologic Cancer Society, Melbourne, Australia, November 8-11, 2014.. 2014.
Chan K.K.L., Low Risk Gestational Trophoblastic Neoplasia, 15th Bienniel Meeting of International Gynecolgica Cancer Society. 2014.
Chan K.K.L., Updates from IGCS, The 5th Ovarian Cancer South China Summit, Shenzhen, 29 Nov.2014 《中華醫學會婦產科腫瘤學分會卵巢癌專題研討會暨第五屆華南卵巢癌高峰論壇》. 2014.
Ho J., DU Y., Wong G.W., Siu K.Y., Chan K.K.L. and Cheung A.N.Y., Downregulation of the Gli Transcription Factors Regulator Kif7 Facilitates Cell Survival and Migration of Choriocarcinoma Cells, PLoS ONE. 2014, 9: e108248.
JIANG Y., Siu K.Y., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Pyruvate dehydrogenase kinase 1 (PDHK1) regulates ovarian cancer cell migration, invasion, and chemoresistance and contributes to poor prognosis in patients, EACR-AACR-SIC Special Conference; 20-23 June 2015; Florence, Italy. Abstract no. 152. 2015.
Lee E.Y.P., Hui S.K., Chan K.K.L., Tse K.Y., Kwong W.K.P., Chang T.Y., Chan Q. and Khong P.L., Relationship between intravoxel incoherent motion diffusion-weighted MRI and dynamic contrast-enhanced MRI in tissue perfusion of cervical cancers, Journal of Magnetic Resonance Imaging. 2014, n/a-n/a.
Lee J.Y., Kim E.Y., Jung K.W., Shin A., Chan K.K.L., Aoki S., Kim J.W., Low J. and Won Y.J., Trends in Gynecologic Cancer Mortality in East Asian Regions, J Gynecol Oncol. 2014, 25 (3).
Siu K.Y., JIANG Y., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Overexpression of Hexokinase 2 (HK2) in ovarian cancer contributes to cell migration, invasion and cancer stem-like cells regulation and correlates with poor patient survival., EACR-AACR-SIC Special Conference; 20-23 June 2015; Florence, Italy. Abstract no. 144. 2015.


Researcher : Chan RWS

Project Title:The Effect of Macrophages on Putative Stem/Progenitor Cells in Endometrium and Endometriosis.
Investigator(s):Chan RWS, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2013
Completion Date:08/2014


Project Title:World Congress of Reproductive Biology 2014; Label retaining stromal cells are involve in uterine remodeling after parturition
Investigator(s):Chan RWS
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2014
Completion Date:09/2014


List of Research Outputs

CAO M., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Label Retaining Stromal Cells Are Involved in Uterine Remodeling after Parturition., World Congress of Reproductive Biology. 2014.
XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Regulatory Mechanism of Endometrial Mesenchymal-like Stem Cells during Menstruation, European Society of Human Reproduction and Embryology. 2015.
Xiang L., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Slow-cycling mesenchymal stromal cells in human endometrium possess common hallmark somatic stem cell properties, Stem Cell Research & Therapy. 2014, 5: 84.


Researcher : Chan YK

Project Title:Validating and examining SNPs identified from genome-wide scanning for disease susceptibility to HBV-related liver cancer in Chinese population
Investigator(s):Chan YK, Ng IOL, Wong CM
Department:Pathology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2010


List of Research Outputs

MAK C.C.Y., Chow P.C., Chau A.K.T., Chan Y.K., Bassett A.S. and Chung B.H.Y., Clinical implications of large rare copy number variations in 110 Chinese patients with conotruncal heart disease (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014.
Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629.
YEUNG K.S., Chee W.Y.Y., Luk H.M., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Shuen A.Y., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Spread of X Inactivation on Chromosome 15 is Associated with a More Severe Phenotype in a Girl with an Unbalanced t(X;15) Translocation, American Journal of Medical Genetics (Part A). 2014, 164(10): 2521-2528.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality – A new condition identified by exome sequencing? , Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 206.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014.


Researcher : Cheung KW

Project Title:A multi-center prospective study on the evaluation of paternal, maternal and obstetric factors leading to the hepatitis B immunization failure in Hong Kong
Investigator(s):Cheung KW, Seto TYM, Kan SYA, Ng EHY, Kou KOT, Lau WL, Wong RMS, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


List of Research Outputs

Cheung K.W. and Cheung V.Y.T., Hysterectomy for abnormal cervical smear when local excision is not possible, J Low Genit Tract Dis.. 2014, 18(3): 235-239.
Cheung K.W. and Cheung V.Y.T., Recurrence of carcinoma of appendix presenting as vulvar swelling: a case report, J Obstet Gynaecol Can. 2014, 36(10): 904-906.
Cheung K.W., Ngu S.F. and Cheung V.Y.T., Sonographic Characteristics Of The Uterus In Asymptomatic Women After Second-trimester Medical Termination Of Pregnancy, J Ultrasound Med. 2015, 34(4): 611-6.


Researcher : Cheung VYT

List of Research Outputs

Cheung K.W. and Cheung V.Y.T., Hysterectomy for abnormal cervical smear when local excision is not possible, J Low Genit Tract Dis.. 2014, 18(3): 235-239.
Cheung K.W. and Cheung V.Y.T., Recurrence of carcinoma of appendix presenting as vulvar swelling: a case report, J Obstet Gynaecol Can. 2014, 36(10): 904-906.
Cheung K.W., Ngu S.F. and Cheung V.Y.T., Sonographic Characteristics Of The Uterus In Asymptomatic Women After Second-trimester Medical Termination Of Pregnancy, J Ultrasound Med. 2015, 34(4): 611-6.
Cheung V.Y.T., High intensity focused ultrasound in treating uterine fibroids., The 6th Asia Pacific Congress on Controversies in Gynecology, Infertility & Ultrasound. Ho Chi Minh City, Vietnam, November 2014.. 2014.
Cheung V.Y.T., Management of ovarian masses during pregnancy, Journal of Paediatrics, Obstetrics & Gynaecology. 2014, 40(4), Jul/Aug: 169-173.
Cheung V.Y.T., Update in the Diagnosis and Management of Abnormal Uterine Bleeding, Certificate Course on Office Gynaecology. The Federation of Medical Societies of Hong Kong. Hong Kong, December 2014.. 2014.
Ko K.Y.J., Li R.H.W. and Cheung V.Y.T., Caesarean scar pregnancy: a 10-year experience, The Australian & New Zealand journal of obstetrics & gynaecology. 2015, 55(1): 64-69.
Ko K.Y.J. and Cheung V.Y.T., In the era for 3D for laparoscopy, The Hong Kong Medical Diary. 2014, 19(9): 10-11.
Lui M.W.E., Ngu S.F. and Cheung V.Y.T., Mullerian cyst of the uterus misdiagnosed as ovarian cyst on pelvic sonography, J Clin Ultrasound. 2014, 42(3): 183-184.


Researcher : Chiu CN

Project Title:The roles of protein disulfide isomerase family A, member 3 (ERp57) and surface thiol/disulfide exchange in spermatozoa-zona pellucida binding and their association with fertilization in vitro.
Investigator(s):Chiu CN, Pang TKR, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction
Investigator(s):Chiu CN, Pang TKR, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Biological properties of complex N-linked oligosaccharides of human oocytes
Investigator(s):Chiu CN, Yeung WSB, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


Project Title:The annual conference of the Society for Reproduction and Fertility; Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human
Investigator(s):Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2014
Completion Date:09/2014


Project Title:The role of galectin-3 in spermatozoa-zona pellucida binding and its association with fertilization in vitro
Investigator(s):Chiu CN, Yeung WSB, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, In: Department of Obstetrics and Gynaecology, CUHK, Symposium on Male Infertility, The Chinese University of Hong Kong, Hong Kong, 27 August 2014. 2014.
Chiu C.N., Glycodelin-A as a paracrine regulator in early pregnancy, In: National Institute of Immunology, International Congress on Embryo Implantation & Pregnancy, National Institute of Immunology, New Delhi, India, 9-11 March 2015. 2015.
Chiu C.N., Lam K.K., Wong R.C. and Yeung W.S.B., The identity of zona pellucida receptor on spermatozoa: an unresolved issue in developmental biology, Semin Cell Dev Biol.. 2014, 30: 86-95.
Ko K.Y.J., HUANG W., Li R.H.W., Yeung W.S.B., Ho P.C. and Chiu C.N., An in vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions, Andrology. 2014, n/a-n/a.
Lee C.L., Yeung W.S.B. and Chiu C.N., Protective role of glycodelin-A on sperm motility during co-culture with macrophage, The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2014.
So K.H., Kodithuwakku S.P., Li R.H.W., Chiu C.N., Cheung A.N.Y., Yeung W.S.B. and Lee C.K.F., Embryonic derived hCG down-regulates olfactomedin-1 thrgouh microRNA-212 in tubal ectopic pregnancy. P10, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Vijayan M., Lee C.L., Lee C.K.F., Yeung W.S.B. and Chiu C.N., Role of glycodelin A in modulating monocyte differentiation and immunomodulatory function of decidual macrophages. P11., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
WONG C.W., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., IBSA poster prize: The roles of ERp57 and surface thiol/disulphide exchange in spermatozoa-zona pellucida binding , In: European Academy of Andrology, 8th European Congress of Andrology, Barcelona, Spain . 2014.


Researcher : Chow JFC

List of Research Outputs

Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C.Y., Ng E.H.Y. and Ho P.C., Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage, Reprod Biol Endocrinol. 2014, 12: 105.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau E.Y.L., Ho P.C. and Ng E.H.Y., Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre, Hong Kong Medical Journal. 2015, 21(4): 299-303.
Wang Q., Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C., Ng E.H.Y. and Ho P.C., Preimplantation genetic diagnosis using combined strategies on a breast cancer patient with a novel genomic deletion in BRCA2, Journal of Assisted Reproduction and Genetics . 2014, 31(12): 1719-1726.


Researcher : Chu MYM

List of Research Outputs

Leung T.W., Liu S., Leung C.Y., Chu M.Y.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis, Journal of Medical Virology. 2015, 87: 1022-1033.


Researcher : Fong SW

List of Research Outputs

CHEN C.H., Lee C.Y.L., Fong S.W. and Yeung W.S.B., Hyperglycemia impedes hESC differentiation into definitive endoderm through modulation of histone methylation patterns, International Society of Stem Cell Research 2015.
Lee C.Y.L., Fong S.W., CHEN C.H., LI T., Yeung W.S.B. and Lee C.K.F., A NOVEL HUMAN EMBRYONIC STEM CELL-DERIVED TROPHOBLASTIC SPHEROID IMPLANTATION MODEL FOR THE STUDY OF EARLY HUMAN IMPLANTATION, International Society Of Stem Cells Research Annual Meeting 2015.


Researcher : HUANG W

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, In: Department of Obstetrics and Gynaecology, CUHK, Symposium on Male Infertility, The Chinese University of Hong Kong, Hong Kong, 27 August 2014. 2014.
Ko K.Y.J., HUANG W., Li R.H.W., Yeung W.S.B., Ho P.C. and Chiu C.N., An in vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions, Andrology. 2014, n/a-n/a.


Researcher : Ho PC

List of Research Outputs

Chan C.H.Y., Chan T.H.Y., Chan C.L.W., Ng E.H.Y. and Ho P.C., Diagnostic ambiguity and psychosocial distress among Chinese women with idiopathic and non-idiopathic infertility , Illness, Crisis & Loss. 2015, 23(1): 45-48.
Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C.Y., Ng E.H.Y. and Ho P.C., Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage, Reprod Biol Endocrinol. 2014, 12: 105.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau E.Y.L., Ho P.C. and Ng E.H.Y., Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre, Hong Kong Medical Journal. 2015, 21(4): 299-303.
Ho P.C., Director of Editorial Board in Obstetrics and Gynaecology, Journal of Paediatrics, Obstetrics and Gynaecology, 1997 till now. 2015.
Ho P.C., Ferring Symposium: Optimisation of ovarian stimulation, National CME Symposium in Obstetrics and Gynaecology, Frontiers In Assisted Reproduction and Reproductive Genetics, October 31-November 2, 2014, Organizers: The University of Hong Kong and The University of Hong Kong, Shenzhen Hospital. 2014.
Ho P.C., Management of Polycystic Ovary Syndrome, 41st AGM and 23rd International Scientific Conference, "Promotion & Protection of Women's Health", September 25-27, 2014, Obstetrical and Gynaecological Society of Bangladesh, Dhaka, Bangladesh. 2014.
Ho P.C., Member of Editorial Board, Chinese Journal of Obstetrics and Gynaecology. 2015.
Ho P.C., Member of Editorial Board, Clinical Obstetrics and Gynaecology (Bailliere Tindall). 2015.
Ho P.C., Member of Editorial Board, Journal of Practical Obstetrics and Gynaecology. 2015.
Ho P.C., Member of Editorial Board, Journal of Reproductive Medicine (China). 2015.
Ho P.C., Member of the Advisory Editorial Board, Asia Oceania Journal of Obstetrics and Gynaecology, 1994 till now. 2015.
Ho P.C., Reviewer for "American Journal of Obstetrics and Gynaecology". 2015.
Ho P.C., Reviewer for "Obstetrics and Gynaecology". 2015.
Ko K.Y.J., HUANG W., Li R.H.W., Yeung W.S.B., Ho P.C. and Chiu C.N., An in vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions, Andrology. 2014, n/a-n/a.
Kodithuwakku S.P., Yeung W.S.B., Ho P.C. and Lee C.K.F., P263, Activation of canonical Wnt-signaling pathway, human chorionic gonadothrophin and progesterone may predispose fallopian tube epithelium to embryo attachment., Proceedings of the Peradeniya University International Research Sessions. 4-5 July 2014, Sri Lanka.. 2014.
Lam K.W., Li R.H.W., Ng E.H.Y., Ho P.C. and Yeung W.S.B., Semen analysis - what a clinician should know, Journal of Paediatrics, Obstetrics and Gynaecology. Singapore, 2015, Jan: 37-44.
Li R.H.W., Lo S.T.S. and Ho P.C., Emergency contraception, Best Practice & Research Clinical Obstetrics & Gynaecology. 2014, 28: 835-844.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Mifepristone, but not levonorgestrel, has suppressive effect on tubal function at pharmacological dose which may contribute to emergency contraceptive action, 47th Annual Meeting of the Society for the Study of Reproduction. 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian Response and Cumulative Live Birth Rate of Women Undergoing In-Vitro Fertilisation Who Had Discordant Anti-Mullerian Hormone and Antral Follicle Count Measurements: A Retrospective Study, PLoS ONE. 2014, 9: e108493.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count measurements: a retrospective study, The 21st World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI). 2015.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count, The 30th Annual Meeting of European Society of Human Reproduction and Embryology, Munich, Germany, June 29 – July 2, 2014 (poster presentation). 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of baseline antral follicle count and anti-Mullerian hormone in the index stimulation cycle of IVF treatment in predicting outcome of subsequent frozen-thawed embryo transfers, Gynecological Endocrinology. 2014, 30: 490-493.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome., Human Reproduction. 2015, 30(9): 2178-2183.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function, Human Reproduction. 2014, 29: 2156-2162.
WONG C.W., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., IBSA poster prize: The roles of ERp57 and surface thiol/disulphide exchange in spermatozoa-zona pellucida binding , In: European Academy of Andrology, 8th European Congress of Andrology, Barcelona, Spain . 2014.
Wang Q., Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C., Ng E.H.Y. and Ho P.C., Preimplantation genetic diagnosis using combined strategies on a breast cancer patient with a novel genomic deletion in BRCA2, Journal of Assisted Reproduction and Genetics . 2014, 31(12): 1719-1726.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders, Fertility and Sterility. 2014, 102: 108-115.e1.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Reply: Endometrial injury and reproductive outcomes: there's more to this story than meets the horse's blind eye, Human Reproduction. 2015, 3: 749-750.


Researcher : Hui MN

List of Research Outputs

Cheung M.C.H., HO S.H., Hui M.N., Wu M.H., Cheung M.P.L., Ho C.K.Y., Niu B., Cheah K.S.E. and LIU A., Sox9 and the Molecular Network Regulating Neural Crest Cell Motility, 2014 International SOX Research Conference. 2014.


Researcher : Hui PW

Project Title:31st British International Congress of Obstetrics & Gynaecology 2007 A rare cause of Thrombocytopenia in Pregnancy-EDTA-dependent Pseudothrombocytopenia
Investigator(s):Hui PW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2007


List of Research Outputs

Wan H.L.T., Hui P.W., Li R.H.W. and Ng E.H.Y., Obstetric outcomes in women with polycystic ovary syndrome and isolated polycystic ovaries undergoing in vitro fertilization: a retrospective cohort analysis, Journal of Maternal and Fetal Neonatal Medicine. 2015, 28: 475-478.


Researcher : JIANG Y

List of Research Outputs

JIANG Y., Siu K.Y., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Pyruvate dehydrogenase kinase 1 (PDHK1) regulates ovarian cancer cell migration, invasion, and chemoresistance and contributes to poor prognosis in patients, EACR-AACR-SIC Special Conference; 20-23 June 2015; Florence, Italy. Abstract no. 152. 2015.
Siu K.Y., JIANG Y., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Overexpression of Hexokinase 2 (HK2) in ovarian cancer contributes to cell migration, invasion and cancer stem-like cells regulation and correlates with poor patient survival., EACR-AACR-SIC Special Conference; 20-23 June 2015; Florence, Italy. Abstract no. 144. 2015.


Researcher : Kan SYA

List of Research Outputs

So J.C.C., Chiang A.K.S., Kan S.Y.A., Lee V.C.Y. and Ng E.H.Y., Beta thalassaemia intermedia due to silent alpha globin gene quadruplication in an infant, Pathology. 2014, 46: 570-572.
Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629.
YEUNG K.S., Chee W.Y.Y., Luk H.M., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Shuen A.Y., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Spread of X Inactivation on Chromosome 15 is Associated with a More Severe Phenotype in a Girl with an Unbalanced t(X;15) Translocation, American Journal of Medical Genetics (Part A). 2014, 164(10): 2521-2528.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality – A new condition identified by exome sequencing? , Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 206.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014.


Researcher : Ko KYJ

List of Research Outputs

Ko K.Y.J., HUANG W., Li R.H.W., Yeung W.S.B., Ho P.C. and Chiu C.N., An in vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions, Andrology. 2014, n/a-n/a.
Ko K.Y.J., Li R.H.W. and Cheung V.Y.T., Caesarean scar pregnancy: a 10-year experience, The Australian & New Zealand journal of obstetrics & gynaecology. 2015, 55(1): 64-69.
Ko K.Y.J. and Cheung V.Y.T., In the era for 3D for laparoscopy, The Hong Kong Medical Diary. 2014, 19(9): 10-11.


Researcher : LEUNG TW

List of Research Outputs

LEUNG T.W., Liu S., Leung C.Y., Chu M.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis., J Med Virol.. 2015, 2015 Jun;87(6):1022-33..
Leung T.W., Liu S., Leung C.Y., Chu M.Y.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis, Journal of Medical Virology. 2015, 87: 1022-1033.


Researcher : LI T

List of Research Outputs

Lee C.Y.L., Fong S.W., CHEN C.H., LI T., Yeung W.S.B. and Lee C.K.F., A NOVEL HUMAN EMBRYONIC STEM CELL-DERIVED TROPHOBLASTIC SPHEROID IMPLANTATION MODEL FOR THE STUDY OF EARLY HUMAN IMPLANTATION, International Society Of Stem Cells Research Annual Meeting 2015.


Researcher : LIANG R

List of Research Outputs

LIANG R., Ngan H.Y.S. and Chan D.W., BCL2A1 Plays a Biphasic Role in Ovarian Cancer Progression, 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.


Researcher : LIU J

List of Research Outputs

CAI C., Shi L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling , 2014.
CAI C., SHI L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling, Oncotarget. USA, Impact Journals, LLC., 2014, 5: 7549-62.
LIU J., Ngan H.Y.S. and Chan D.W., Identification of cisplatin-resistance related genes in Ovarian clear cell carcinoma using 3D cell culture model., 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.
LIU J., Ngan H.Y.S. and Chan D.W., Identification of cisplatin-resistance related genes in ovarian clear cell carcinoma using 3D cell culture system, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic held in Florence of Italy, from June 20th to 23rd, 2015.


Researcher : Lam KW

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, In: Department of Obstetrics and Gynaecology, CUHK, Symposium on Male Infertility, The Chinese University of Hong Kong, Hong Kong, 27 August 2014. 2014.
Lam K.W., Li R.H.W., Ng E.H.Y., Ho P.C. and Yeung W.S.B., Semen analysis - what a clinician should know, Journal of Paediatrics, Obstetrics and Gynaecology. Singapore, 2015, Jan: 37-44.
WONG C.W., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., IBSA poster prize: The roles of ERp57 and surface thiol/disulphide exchange in spermatozoa-zona pellucida binding , In: European Academy of Andrology, 8th European Congress of Andrology, Barcelona, Spain . 2014.


Researcher : Lam KW

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, In: Department of Obstetrics and Gynaecology, CUHK, Symposium on Male Infertility, The Chinese University of Hong Kong, Hong Kong, 27 August 2014. 2014.
Lam K.W., Li R.H.W., Ng E.H.Y., Ho P.C. and Yeung W.S.B., Semen analysis - what a clinician should know, Journal of Paediatrics, Obstetrics and Gynaecology. Singapore, 2015, Jan: 37-44.
WONG C.W., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., IBSA poster prize: The roles of ERp57 and surface thiol/disulphide exchange in spermatozoa-zona pellucida binding , In: European Academy of Andrology, 8th European Congress of Andrology, Barcelona, Spain . 2014.


Researcher : Lam SK

List of Research Outputs

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Effect of Work-Family Conflict on Antenatal Maternal Depression across pregnancy, The International Marcé Scientific Society Conference, Swansea university, Wales, United Kingdom. 2014.


Researcher : Lam YH

Project Title:11th World Congress on Ultrasound in Obstetrics and Gynecology Integrated First and Second Trimester Screening for Down Syndrome
Investigator(s):Lam YH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2001




Researcher : Lao TTH

Project Title:The First Congress on Obstetrics, Gynecology & Infertility Does Impaired Glucose Tolerance Impact on Pregnancy Outcome?
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/1999


Project Title:Dietary caloric intake and the development of gestational diabetes mellitus in at-risk Chinese women
Investigator(s):Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:Elevated TNF-α in gestational diabetes mellitus-cause or consequence?
Investigator(s):Lao TTH, Leung WC, Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The relationship between the antioxidant defense system with the development of gestational diabetes mellitus and its complications in the Chinese population.
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2005




Researcher : Lau ETK

List of Research Outputs

Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629.
YEUNG K.S., Chee W.Y.Y., Luk H.M., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Shuen A.Y., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Spread of X Inactivation on Chromosome 15 is Associated with a More Severe Phenotype in a Girl with an Unbalanced t(X;15) Translocation, American Journal of Medical Genetics (Part A). 2014, 164(10): 2521-2528.


Researcher : Lau EYL

List of Research Outputs

Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C.Y., Ng E.H.Y. and Ho P.C., Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage, Reprod Biol Endocrinol. 2014, 12: 105.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau E.Y.L., Ho P.C. and Ng E.H.Y., Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre, Hong Kong Medical Journal. 2015, 21(4): 299-303.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian Response and Cumulative Live Birth Rate of Women Undergoing In-Vitro Fertilisation Who Had Discordant Anti-Mullerian Hormone and Antral Follicle Count Measurements: A Retrospective Study, PLoS ONE. 2014, 9: e108493.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count measurements: a retrospective study, The 21st World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI). 2015.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count, The 30th Annual Meeting of European Society of Human Reproduction and Embryology, Munich, Germany, June 29 – July 2, 2014 (poster presentation). 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of baseline antral follicle count and anti-Mullerian hormone in the index stimulation cycle of IVF treatment in predicting outcome of subsequent frozen-thawed embryo transfers, Gynecological Endocrinology. 2014, 30: 490-493.
Wang Q., Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C., Ng E.H.Y. and Ho P.C., Preimplantation genetic diagnosis using combined strategies on a breast cancer patient with a novel genomic deletion in BRCA2, Journal of Assisted Reproduction and Genetics . 2014, 31(12): 1719-1726.


Researcher : Lau SK

List of Research Outputs

Liu S., Chan Y.K., Leung C.Y., Yip M.W., Lau S.K., Liao X.Y., Jiang L.L., Luk M.H.M., Lo S.S., Cheung A.N.Y., Lin Z.Q. and Ngan H.Y.S., Human papillomavirus status in southern Chinese women, Hong Kong Med J. 2014, 2014;20(Suppl 6):S35-8.


Researcher : Lee CKF

Project Title:Functional characterization of VAD1.3, a novel acrosome-specific protein by conditional tissue-specific gene inactivation
Investigator(s):Lee CKF, Cheah KSE, Yeung WSB, Luk JMC, Lee NPY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006


Project Title:Environmental Screening, Computational and Biological Characterization of Endocrine Disruptors, in Respect to Receptor Binding, Embryo and Gonad Physiology
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2009


Project Title:Functional roles of human chorionic gonadotropin (hCG) and Wnt-signaling molecules on tubal ectopic pregnancy
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2013
Completion Date:10/2014


Project Title:Embryo-Female Reproductive Tract Interaction: A study on the role of embryo-derived factor(s) on endometrial receptivity through microRNA regulation
Investigator(s):Lee CKF, Ng EHY, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Mechanistic actions of embryotrophic factor iC3b on in vitro embryo development
Investigator(s):Lee CKF, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2014


Project Title:The 47th Annual Meeting of the Society for the Study of Reproduction; Bisphenol A Suppresses Trophoblastic Spheroids Attachment onto Endometrial cells through Estrogen Receptor and Wnt-Signaling Pathways
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2014
Completion Date:07/2014


Project Title:Human embryonic stem cell-derived trophoblastic cells for the development of a novel implantation model
Investigator(s):Lee CKF, Ng EHY, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Studies on Human Endometrial Receptivity by profiling and function studies of surface proteins of human endometrial cell lines
Investigator(s):Lee CKF, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2015


List of Research Outputs

Kodithuwakku S.P., Yeung W.S.B., Ho P.C. and Lee C.K.F., P263, Activation of canonical Wnt-signaling pathway, human chorionic gonadothrophin and progesterone may predispose fallopian tube epithelium to embryo attachment., Proceedings of the Peradeniya University International Research Sessions. 4-5 July 2014, Sri Lanka.. 2014.
Kottawatta S.A., So K.H., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., OP3. The 3’-UTR of olfactomedin-1 and C-terminal binding protein-1 contain miR-212 regulatory sequence responsible for hCG regulation in human endometrial cells, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Krishanthe K.A.C., Abegunawardana W.W., Rathnayake C., Wijayagunawardane M.P.B., Lee C.K.F. and Kodithuwakku S.P., P163. Effects of fungicide “Mancozeb” on bovine spermatozoa, Proceedings of the Peradeniya Univ. International Research Sessions. 4-5 July 2014, Sri Lanka. .. 2014.
LIU J., Sze C.W.S., Lee C.K.F. and Zhang Y., Abstract and poster presentation: Aquaporin9 is a promising novel biomarker and therapeutic target for Alzheimer's disease. , In: Liu JY, Sze CW, Lee KF. Zhang YB*., Cell Symposia: Translational Neuroscience 2014. Nov 13-14, 2014. Arlington, VA, USA. Organization by the editors of Cell Press's leading journals. 2014.11.13-14. . 2014, P2.39.
LIU J., CHEN X., Tang S.C.W., Lao L., Sze C.W.S., Lee C.K.F. and Zhang Y., Edible plants from traditional Chinese medicine is a promising alternative for the management of diabetic nephropathy, In: Jing-Yi Liu, Xiao-Xin Chen, Sydney Chi-Wai Tang, Li-Xing Lao, Stephen Cho-Wing Sze, Kai-Fai Lee, Yanbo Zhang, Journal of Functional Foods [IF 4.48]. 2015, 14(2015): 12-22.
LIU J., Tang S.C.W., Sze C.W.S., Lao L., Ho J.C.M., Lee C.K.F. and Zhang Y., Paper and poster presentation: Traditional Chinese Medicine is a Promising Alternative for the Management of Diabetic Nephropathy. , In: Liu JY, Tang SCW, Sze SCW, Lao LX, Ho JCM, Lee CKF, Zhang YB*. , The 8th Pong Ding Yuen International Symposium on Traditional Chinese Medicine cum, The 2nd International Chinese Symposium on Free Radical Research & The 6th Symposium for Three Districts of Cross-straits on Free Radical Research 15 -16/11/2014, Hong Kong. Organized by Commission of Free Radical Biology and Medicine, Biophysical Society of China and Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014.11.15-16. . 2014, p-60.
Lee C.Y.L., Fong S.W., CHEN C.H., LI T., Yeung W.S.B. and Lee C.K.F., A NOVEL HUMAN EMBRYONIC STEM CELL-DERIVED TROPHOBLASTIC SPHEROID IMPLANTATION MODEL FOR THE STUDY OF EARLY HUMAN IMPLANTATION, International Society Of Stem Cells Research Annual Meeting 2015.
Li T.K.T., Li Y.X., Li R.H.W., Yeung T.T., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The endocrine disruptor perflurooctanesulfonate (PFOS) modulates embryo implantation through Wnt/b-catenin inhibition. P06., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Liu J., Petersen N.J., Lee C.K.F., Hansen S.H., Lao L., Sze C.W. and Zhang Y., Application of temperature-correlated mobility theory for optimizing the MEKC separation of the main lignans from Schisandra Chinensis Fructus and its prescription Yuye Decoction, Electrophoresis. 2014.
So K.H., Kodithuwakku S.P., Li R.H.W., Chiu C.N., Cheung A.N.Y., Yeung W.S.B. and Lee C.K.F., Embryonic derived hCG down-regulates olfactomedin-1 thrgouh microRNA-212 in tubal ectopic pregnancy. P10, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Vijayan M., Lee C.L., Lee C.K.F., Yeung W.S.B. and Chiu C.N., Role of glycodelin A in modulating monocyte differentiation and immunomodulatory function of decidual macrophages. P11., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.


Researcher : Lee CL

Project Title:The role of soluble human leukocyte antigen G5 on decidual macrophage differentiation
Investigator(s):Lee CL, Yeung WSB, Chiu CN, Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, In: Department of Obstetrics and Gynaecology, CUHK, Symposium on Male Infertility, The Chinese University of Hong Kong, Hong Kong, 27 August 2014. 2014.
Lee C.L., Yeung W.S.B. and Chiu C.N., Protective role of glycodelin-A on sperm motility during co-culture with macrophage, The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2014.
Vijayan M., Lee C.L., Lee C.K.F., Yeung W.S.B. and Chiu C.N., Role of glycodelin A in modulating monocyte differentiation and immunomodulatory function of decidual macrophages. P11., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.


Researcher : Lee CP

List of Research Outputs

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Effect of Work-Family Conflict on Antenatal Maternal Depression across pregnancy, The International Marcé Scientific Society Conference, Swansea university, Wales, United Kingdom. 2014.
Cheuk Q.K.Y., Lo T.K., Lee C.P. and Yeung A.P.C., Double balloon catheter for induction of labour in Chinese women with previous caesarean section: one-year experience and literature review, Hong Kong Medical Journal. 2015.


Researcher : Lee CYL

List of Research Outputs

CHEN C.H., Lee C.Y.L., Fong S.W. and Yeung W.S.B., Hyperglycemia impedes hESC differentiation into definitive endoderm through modulation of histone methylation patterns, International Society of Stem Cell Research 2015.
Lee C.Y.L., Fong S.W., CHEN C.H., LI T., Yeung W.S.B. and Lee C.K.F., A NOVEL HUMAN EMBRYONIC STEM CELL-DERIVED TROPHOBLASTIC SPHEROID IMPLANTATION MODEL FOR THE STUDY OF EARLY HUMAN IMPLANTATION, International Society Of Stem Cells Research Annual Meeting 2015.


Researcher : Lee VCY

List of Research Outputs

Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C.Y., Ng E.H.Y. and Ho P.C., Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage, Reprod Biol Endocrinol. 2014, 12: 105.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau E.Y.L., Ho P.C. and Ng E.H.Y., Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre, Hong Kong Medical Journal. 2015, 21(4): 299-303.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian Response and Cumulative Live Birth Rate of Women Undergoing In-Vitro Fertilisation Who Had Discordant Anti-Mullerian Hormone and Antral Follicle Count Measurements: A Retrospective Study, PLoS ONE. 2014, 9: e108493.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count measurements: a retrospective study, The 21st World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI). 2015.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count, The 30th Annual Meeting of European Society of Human Reproduction and Embryology, Munich, Germany, June 29 – July 2, 2014 (poster presentation). 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of baseline antral follicle count and anti-Mullerian hormone in the index stimulation cycle of IVF treatment in predicting outcome of subsequent frozen-thawed embryo transfers, Gynecological Endocrinology. 2014, 30: 490-493.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome., Human Reproduction. 2015, 30(9): 2178-2183.
So J.C.C., Chiang A.K.S., Kan S.Y.A., Lee V.C.Y. and Ng E.H.Y., Beta thalassaemia intermedia due to silent alpha globin gene quadruplication in an infant, Pathology. 2014, 46: 570-572.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders, Fertility and Sterility. 2014, 102: 108-115.e1.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Reply: Endometrial injury and reproductive outcomes: there's more to this story than meets the horse's blind eye, Human Reproduction. 2015, 3: 749-750.


Researcher : Leung CY

List of Research Outputs

LEUNG T.W., Liu S., Leung C.Y., Chu M.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis., J Med Virol.. 2015, 2015 Jun;87(6):1022-33..
Leung T.W., Liu S., Leung C.Y., Chu M.Y.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis, Journal of Medical Virology. 2015, 87: 1022-1033.
Liu S., Chan Y.K., Leung C.Y., Yip M.W., Lau S.K., Liao X.Y., Jiang L.L., Luk M.H.M., Lo S.S., Cheung A.N.Y., Lin Z.Q. and Ngan H.Y.S., Human papillomavirus status in southern Chinese women, Hong Kong Med J. 2014, 2014;20(Suppl 6):S35-8.


Researcher : Leung KC

List of Research Outputs

Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014.


Researcher : Leung KY

List of Research Outputs

Chan C.Y., Lee A.M., Lam S.K., Lee C.P., Leung K.Y., Koh Y.W. and Tang C.S.K., Effect of Work-Family Conflict on Antenatal Maternal Depression across pregnancy, The International Marcé Scientific Society Conference, Swansea university, Wales, United Kingdom. 2014.


Researcher : Leung ON

Project Title:Epigenetic modulation of Sox9 in HCC
Investigator(s):Leung ON, Lo CLR
Department:Pathology
Source(s) of Funding:Small Project Funding
Start Date:06/2015


List of Research Outputs

Pang T.K.R., Leung O.N., YUEN C.K. and Yeung W.S.B., MicroRNA-135a induced formation of CD133+ cell sub-population with cancer-initiating cell properties in cervical cancer, 15th Society of Chinese Bioscientists in America International Symposium. Taiwan, 2015.
Pang T.K.R., Leung O.N., Ngan H.Y.S. and Yeung W.S.B., miR-135a induced formation of cancer-initialing cell subpopulation in cervical cancer, EMBO Conference Stem Cells in Cancer and Regenerative Medicine. 2014, 130.
Ye T., Pang T.K.R., Leung O.N., Chiu J.F. and Yeung W.S.B., Two-dimensional liquid chromatography with tandem mass spectrometry-based proteomic characterization of endometrial luminal epithelial surface proteins responsible for embryo implantation., In: Craig Niederberger, MD, Chicago, Illinois, USA Antonio Pellicer, MD, Valencia, Spain, Fertility and Sterility. USA, Elsevier, 2015, 103: 853-61e3.


Researcher : Leung THY

Project Title:Clinical correlation of DNp73/C35/HER2 and their cooperative effects in ovarian cancer.
Investigator(s):Leung THY, Ngan HYS, Cheung ANY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:05/2013
Completion Date:11/2014


List of Research Outputs

CAI C., Shi L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling , 2014.
CAI C., SHI L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling, Oncotarget. USA, Impact Journals, LLC., 2014, 5: 7549-62.


Researcher : Leung TW

List of Research Outputs

LEUNG T.W., Liu S., Leung C.Y., Chu M.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis., J Med Virol.. 2015, 2015 Jun;87(6):1022-33..
Leung T.W., Liu S., Leung C.Y., Chu M.Y.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis, Journal of Medical Virology. 2015, 87: 1022-1033.


Researcher : Li RHW

Project Title:An in vitro study of endocrine factors regulating expression of anti-Mullerian hormone in human granulosa cells
Investigator(s):Li RHW, Yeung WSB, Cheung ANY, Ng EHY, Ho PC, O WS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2013


Project Title:A randomised trial to compare antral follicle count and serum anti-Mullerian hormone level for determination of gonadotrophin dosing in in-vitro fertilisation
Investigator(s):Li RHW, Lee VCY, Yeung TWY, Chai J, Lau EYL, Yeung WSB, Ho PC, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


Project Title:Evaluation of the diagnostic performance of serum anti-Mullerian hormone for polycystic ovary syndrome using the ultrasensitive ELISA kit
Investigator(s):Li RHW, Yeung WSB, Ho PC, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2015


Project Title:Role of adrenomedullin and inflammatory mediators in pathogenesis of tubal ectopic pregnancy
Investigator(s):Li RHW, Cheung BMY, O WS, Lee CKF, Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


List of Research Outputs

Chai J., Lee V.C., Yeung T.W., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment, PLoS One. 2015, 10(3).
Ko K.Y.J., HUANG W., Li R.H.W., Yeung W.S.B., Ho P.C. and Chiu C.N., An in vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions, Andrology. 2014, n/a-n/a.
Ko K.Y.J., Li R.H.W. and Cheung V.Y.T., Caesarean scar pregnancy: a 10-year experience, The Australian & New Zealand journal of obstetrics & gynaecology. 2015, 55(1): 64-69.
Lam K.W., Li R.H.W., Ng E.H.Y., Ho P.C. and Yeung W.S.B., Semen analysis - what a clinician should know, Journal of Paediatrics, Obstetrics and Gynaecology. Singapore, 2015, Jan: 37-44.
Li R.H.W., Lo S.T.S. and Ho P.C., Emergency contraception, Best Practice & Research Clinical Obstetrics & Gynaecology. 2014, 28: 835-844.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Mifepristone, but not levonorgestrel, has suppressive effect on tubal function at pharmacological dose which may contribute to emergency contraceptive action, 47th Annual Meeting of the Society for the Study of Reproduction. 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian Response and Cumulative Live Birth Rate of Women Undergoing In-Vitro Fertilisation Who Had Discordant Anti-Mullerian Hormone and Antral Follicle Count Measurements: A Retrospective Study, PLoS ONE. 2014, 9: e108493.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count measurements: a retrospective study, The 21st World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI). 2015.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count, The 30th Annual Meeting of European Society of Human Reproduction and Embryology, Munich, Germany, June 29 – July 2, 2014 (poster presentation). 2014.
Li R.H.W., Cheung C.L., Tan K.C.B., Sham P.C., Kung A.W.C. and Tang G.W.K., Replication study of genetic loci influencing age at menopause in Southern Chinese women., The 10th European Congress on Menopause and Andropause, Madrid, May 2015.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of baseline antral follicle count and anti-Mullerian hormone in the index stimulation cycle of IVF treatment in predicting outcome of subsequent frozen-thawed embryo transfers, Gynecological Endocrinology. 2014, 30: 490-493.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome., Human Reproduction. 2015, 30(9): 2178-2183.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function, Human Reproduction. 2014, 29: 2156-2162.
Li T.K.T., Li Y.X., Li R.H.W., Yeung T.T., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The endocrine disruptor perflurooctanesulfonate (PFOS) modulates embryo implantation through Wnt/b-catenin inhibition. P06., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Ng E.H.Y., Li R.H.W., Chen L., Lan V.T.N., Tuong H.M. and Quan S., A randomized double blind comparison of atosiban in patients undergoing IVF treatment, Human Reproduction. 2014, 29: 2687-2694.
So K.H., Kodithuwakku S.P., Li R.H.W., Chiu C.N., Cheung A.N.Y., Yeung W.S.B. and Lee C.K.F., Embryonic derived hCG down-regulates olfactomedin-1 thrgouh microRNA-212 in tubal ectopic pregnancy. P10, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Wan H.L.T., Hui P.W., Li R.H.W. and Ng E.H.Y., Obstetric outcomes in women with polycystic ovary syndrome and isolated polycystic ovaries undergoing in vitro fertilization: a retrospective cohort analysis, Journal of Maternal and Fetal Neonatal Medicine. 2015, 28: 475-478.
Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014.
Yeung T.W., Chai J., Li R.H.W., Lee V.C., Ho P.C. and Ng E.H.Y., The effect of endometrial injury on ongoing pregnancy rate in unselected subfertile women undergoing in vitro fertilization: a randomized controlled trial, Human Reproduction. 2014, 29: 2474-2481.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders, Fertility and Sterility. 2014, 102: 108-115.e1.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Reply: Endometrial injury and reproductive outcomes: there's more to this story than meets the horse's blind eye, Human Reproduction. 2015, 3: 749-750.


Researcher : Li TKT

List of Research Outputs

Li T.K.T., Li Y.X., Li R.H.W., Yeung T.T., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The endocrine disruptor perflurooctanesulfonate (PFOS) modulates embryo implantation through Wnt/b-catenin inhibition. P06., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.


Researcher : Liao S

Project Title:Molecular regulation of meiotic resumption and chromosome segregation in mouse and human oocytes
Investigator(s):Liao S
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


List of Research Outputs

Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Mifepristone, but not levonorgestrel, has suppressive effect on tubal function at pharmacological dose which may contribute to emergency contraceptive action, 47th Annual Meeting of the Society for the Study of Reproduction. 2014.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function, Human Reproduction. 2014, 29: 2156-2162.


Researcher : Liu S

List of Research Outputs

LEUNG T.W., Liu S., Leung C.Y., Chu M.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis., J Med Virol.. 2015, 2015 Jun;87(6):1022-33..
Leung T.W., Liu S., Leung C.Y., Chu M.Y.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis, Journal of Medical Virology. 2015, 87: 1022-1033.
Liu S., Chan Y.K., Leung C.Y., Yip M.W., Lau S.K., Liao X.Y., Jiang L.L., Luk M.H.M., Lo S.S., Cheung A.N.Y., Lin Z.Q. and Ngan H.Y.S., Human papillomavirus status in southern Chinese women, Hong Kong Med J. 2014, 2014;20(Suppl 6):S35-8.


Researcher : Liu VWS

List of Research Outputs

CAI C., Shi L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling , 2014.
CAI C., SHI L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling, Oncotarget. USA, Impact Journals, LLC., 2014, 5: 7549-62.


Researcher : Liu W

Project Title:Roles of microRNA lethal-7 on blastulation of mice embryos
Investigator(s):Liu W, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2014




Researcher : Lo STS

List of Research Outputs

Li R.H.W., Lo S.T.S. and Ho P.C., Emergency contraception, Best Practice & Research Clinical Obstetrics & Gynaecology. 2014, 28: 835-844.


Researcher : Lui MWE

List of Research Outputs

Lui M.W.E., Ngu S.F. and Cheung V.Y.T., Mullerian cyst of the uterus misdiagnosed as ovarian cyst on pelvic sonography, J Clin Ultrasound. 2014, 42(3): 183-184.


Researcher : MAK SL

List of Research Outputs

Chan D.W., MAK S.L. and Ngan H.Y.S., MiR-141 not only modulates anoikis resistance of ovarian cancer cells but also alters pre-metastatic niche for ovarian cancer cell metastatic colonization, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic. Florence of Italy, from June 20th to 23rd,2015.
Chan D.W., MAK S.L. and Ngan H.Y.S., Role of Has-miR-141 as a therapeutic target and predictive biomarker for ovarian cancer, Cold Spring Harbour Asia-Precision Cancer Biology and Medicine. 2015.


Researcher : Ng EHY

Project Title:The 17th IFFS World Congress on Fertility and Sterility 1) Measurement of Serum CA-125 Concentrations Does not Improve the Value of Chlamydia Trachomatis Antibody (CAT) in Predicting Tubal Pathology at Laparoscopy 2) A Comparison of the Pain Levels During Egg Collection and Postoperative Side Effects Using Paracervical Block with and without Conscious Sedation
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2001


Project Title:Comparison of the prevalence of polycystic ovary only and polycystic ovary syndrome between two different ethnic populations
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:Role of Sirt1 in generation of mouse induced pluripotent stem cells
Investigator(s):Ng EHY, Lee CKF, Lee CYL, Ng RK, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:Control of human decidual macrophage differentiation by glycodelin-A
Investigator(s):Ng EHY, Chiu CN, Lee CL, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2012


Project Title:A randomized controlled trial on the effect of endometrial injury on improving ongoing pregnancy rate in subfertile women undergoing in vitro fertilization treatment
Investigator(s):Ng EHY, Li RHW, Lee CKF, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2014
Completion Date:12/2014


Project Title:2014 ASRM Annual meeting ; A RANDOMIZED DOUBLE BLIND COMPARISON OF ATOSIBAN IN UNSELECTED PATIETNS UNDERGOING IN VITRO FERTILIZATION TREATMENT
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2014
Completion Date:10/2014


Project Title:A randomized controlled trial on the effect of endometrial injury on improving the live birth rate in infertile women undergoing in vitro fertilization treatment with repeated implantation failure
Investigator(s):Ng EHY, Chai J, Li RHW, Lee CKF, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2015


List of Research Outputs

CAO M., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Label Retaining Stromal Cells Are Involved in Uterine Remodeling after Parturition., World Congress of Reproductive Biology. 2014.
Chai J., Lee V.C., Yeung T.W., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment, PLoS One. 2015, 10(3).
Chan C.H.Y., Chan T.H.Y., Chan C.L.W., Ng E.H.Y. and Ho P.C., Diagnostic ambiguity and psychosocial distress among Chinese women with idiopathic and non-idiopathic infertility , Illness, Crisis & Loss. 2015, 23(1): 45-48.
Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C.Y., Ng E.H.Y. and Ho P.C., Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage, Reprod Biol Endocrinol. 2014, 12: 105.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau E.Y.L., Ho P.C. and Ng E.H.Y., Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre, Hong Kong Medical Journal. 2015, 21(4): 299-303.
Glasier A., Gemzell-Danielsson K., Bouchard P., Genazzani A.R., Al-Azzawi F., Berga S., Birkhaeuser M., Brincat M., De Melo N.R., Foidart J.M., Kenemans P., Lunenfeld B, Maruo T., Milewicz A., Naftolin F., Ng E.H.Y., Schindler A., Simon C., Simoncini T., Simpson E., Siseles N., Smetnik V. and Tarlatzis B., von Schoultz B., ISGE statement on oral emergency contraception, Gynecological Endocrinology. 2014, 30: 681-682.
Kottawatta S.A., So K.H., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., OP3. The 3’-UTR of olfactomedin-1 and C-terminal binding protein-1 contain miR-212 regulatory sequence responsible for hCG regulation in human endometrial cells, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Lam K.W., Li R.H.W., Ng E.H.Y., Ho P.C. and Yeung W.S.B., Semen analysis - what a clinician should know, Journal of Paediatrics, Obstetrics and Gynaecology. Singapore, 2015, Jan: 37-44.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Mifepristone, but not levonorgestrel, has suppressive effect on tubal function at pharmacological dose which may contribute to emergency contraceptive action, 47th Annual Meeting of the Society for the Study of Reproduction. 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian Response and Cumulative Live Birth Rate of Women Undergoing In-Vitro Fertilisation Who Had Discordant Anti-Mullerian Hormone and Antral Follicle Count Measurements: A Retrospective Study, PLoS ONE. 2014, 9: e108493.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count measurements: a retrospective study, The 21st World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI). 2015.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count, The 30th Annual Meeting of European Society of Human Reproduction and Embryology, Munich, Germany, June 29 – July 2, 2014 (poster presentation). 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of baseline antral follicle count and anti-Mullerian hormone in the index stimulation cycle of IVF treatment in predicting outcome of subsequent frozen-thawed embryo transfers, Gynecological Endocrinology. 2014, 30: 490-493.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome., Human Reproduction. 2015, 30(9): 2178-2183.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function, Human Reproduction. 2014, 29: 2156-2162.
Li T.K.T., Li Y.X., Li R.H.W., Yeung T.T., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The endocrine disruptor perflurooctanesulfonate (PFOS) modulates embryo implantation through Wnt/b-catenin inhibition. P06., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Ng E.H.Y., 2014年度国家科技进步奖二等多囊卵巢综合征病证结合研究的示范和应用in collaboration with the Heilongjiang University of Chinese Medicine, 2014.
Ng E.H.Y., Li R.H.W., Chen L., Lan V.T.N., Tuong H.M. and Quan S., A randomized double blind comparison of atosiban in patients undergoing IVF treatment, Human Reproduction. 2014, 29: 2687-2694.
Ng E.H.Y., Current opinion on the use of LH in IVF, 20th Annual Convention of The Philippine Society of Reproductive Endocrinology and Infertility, Manila, Philippine, 8-10 October 2014. 2014.
Ng E.H.Y., Harbin Consensus Conference Workshop Group. (2014) Improving the Reporting of Clinical Trials of Infertility Treatments (IMPRINT): modifying the CONSORT statement, Fertility and Sterility. 2014, 102(4): 952-959.e15.
Ng E.H.Y., Legro R.S., Wu X., Barnhart K.T., Farquhar C., Fauser B.C. and Mol B., Harbin Consensus Conference Workshop Group; Conference Chairs: Improving the Reporting of Clinical Trials of Infertility Treatments (IMPRINT): modifying the CONSORT statement, Human Reproduction. 2014, 29(10): 2075-2082.
Ng E.H.Y., International Cooperation Award in Chinese Reproductive Medicine, Specialty Committee of Reproductive Medicine, World Federation of Chinese Medicine Societies, 2015.
Ng E.H.Y., Luteal Phase Support in ART, 20th Annual Convention of The Philippine Society of Reproductive Endocrinology and Infertility, Manila, Philippine, 8-10 October 2014. 2014.
Ng E.H.Y., Management of repeated implantation failure, 20th Annual Convention of The Philippine Society of Reproductive Endocrinology and Infertility, Manila, Philippine, 8-10 October 2014. 2014.
Ng E.H.Y., The Usefulness of Serum Progesterone Levels on Day of HCG Administration, 20th Annual Convention of The Philippine Society of Reproductive Endocrinology and Infertility, Manila, Philippine, 8-10 October 2014. 2014.
Ng E.H.Y., 不孕症临床试验的研究伦理学 , National CME Symposium in Obstetrics and Gynaecology, Frontiers In Assisted Reproduction and Reproductive Genetics, October 31-November 2, 2014, Organizers: The University of Hong Kong and The University of Hong Kong, Shenzhen Hospital. 2014.
Ng E.H.Y., 如何设计临床试验 , National CME Symposium in Obstetrics and Gynaecology, Frontiers In Assisted Reproduction and Reproductive Genetics, October 31-November 2, 2014, Organizers: The University of Hong Kong and The University of Hong Kong, Shenzhen Hospital. 2014.
So J.C.C., Chiang A.K.S., Kan S.Y.A., Lee V.C.Y. and Ng E.H.Y., Beta thalassaemia intermedia due to silent alpha globin gene quadruplication in an infant, Pathology. 2014, 46: 570-572.
Wan H.L.T., Hui P.W., Li R.H.W. and Ng E.H.Y., Obstetric outcomes in women with polycystic ovary syndrome and isolated polycystic ovaries undergoing in vitro fertilization: a retrospective cohort analysis, Journal of Maternal and Fetal Neonatal Medicine. 2015, 28: 475-478.
Wang Q., Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C., Ng E.H.Y. and Ho P.C., Preimplantation genetic diagnosis using combined strategies on a breast cancer patient with a novel genomic deletion in BRCA2, Journal of Assisted Reproduction and Genetics . 2014, 31(12): 1719-1726.
Wu X., Ng E.H.Y., Stener-Victorin E. and Legro R.S., Effects and Mechanisms of Complementary and Alternative Medicine during the Reproductive Process, Evidence-Based Complementary and Alternative Medicine. 2014, 2014: 1-2.
XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Regulatory Mechanism of Endometrial Mesenchymal-like Stem Cells during Menstruation, European Society of Human Reproduction and Embryology. 2015.
Xiang L., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Slow-cycling mesenchymal stromal cells in human endometrium possess common hallmark somatic stem cell properties, Stem Cell Research & Therapy. 2014, 5: 84.
Yeung T.W., Chai J., Li R.H.W., Lee V.C., Ho P.C. and Ng E.H.Y., The effect of endometrial injury on ongoing pregnancy rate in unselected subfertile women undergoing in vitro fertilization: a randomized controlled trial, Human Reproduction. 2014, 29: 2474-2481.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders, Fertility and Sterility. 2014, 102: 108-115.e1.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Reply: Endometrial injury and reproductive outcomes: there's more to this story than meets the horse's blind eye, Human Reproduction. 2015, 3: 749-750.
Zheng Y., Stener-Victorin E., Ng E.H.Y., Li J., Wu X. and Ma H., How does acupuncture affect insulin sensitivity in women with polycystic ovary syndrome and insulin resistance? Study protocol of a prospective pilot study, British Medical Journal Open. 2015, 5(4): e007757-e007757.


Researcher : Ng TY

Project Title:A propective randomised controlled trial: prevention of lymphedema by omentoplasty after pelvic lymphadenectomy
Investigator(s):Ng TY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Low Budget High Impact Programme
Start Date:11/2001




Researcher : Ngai CSW

Project Title:Vaginal misoprostol for first trimester termination of pregnancy prior to 9 weeks of gestation
Investigator(s):Ngai CSW, Tang FOS, Chan YM, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:05/1999


Project Title:Cervical assessment in prediction of preterm labour: is three-dimensional ultrasonography a better choice?
Investigator(s):Ngai CSW, Lao TTH, Chen M, Leung KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Multiple pregnancy and gestational diabetes: a physiological response or a pathologic condition?
Investigator(s):Ngai CSW, Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The XIXth Asian and Oceanic Congress of Obstetrics & Gynaecology Should We Screen Sexually Transmitted Diseases for Women Requesting for Termination of Pregnancy?
Investigator(s):Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2005




Researcher : Ngan HYS

Project Title:High dose cis-platinum and cyclophosphamide vs taxol in ovarian cancer
Investigator(s):Ngan HYS, Wong RLC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:07/1994


Project Title:Functional characterization and clinical significance of DNp73-C35 in ovarian cancer
Investigator(s):Ngan HYS, Chan KKL, Cheung ANY, Leung THY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2011
Completion Date:09/2014


Project Title:Clinical significance and application of HPV-related microRNAs in cervical pre-maglinant lesions and cancer
Investigator(s):Ngan HYS, Liu S, Ng EKO, Cheung ANY, Chan KKL, Kwong A
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013


Project Title:Roles of CD55(+) population and HPV viral proteins on tumor progression in cervical cancer cells
Investigator(s):Ngan HYS, Leung THY, Cheung ANY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2013
Completion Date:08/2014


Project Title:Roles of HPV-E6 protein and CD55(+) population in regulating radio-resistance in cervical cancer cells
Investigator(s):Ngan HYS, Chan KKL, Leung THY, Cheung ANY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013


Project Title:Functional characterization of subpopulation cells expressing transferrin receptor (CD71) and the roles of HPV viral protein in cervical cancer
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


Project Title:Functional characterization of CD71(+) population and the roles of HPV-E6 protein in cervical cancer
Investigator(s):Ngan HYS, Chan KKL, Cheung ANY, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2014


Project Title:Elucidating the potential role of CD109 as a cancer stem-like cell marker in cervical cancer
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:04/2015


List of Research Outputs

CAI C., Shi L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling , 2014.
CAI C., SHI L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling, Oncotarget. USA, Impact Journals, LLC., 2014, 5: 7549-62.
Chan D.W., MAK S.L. and Ngan H.Y.S., MiR-141 not only modulates anoikis resistance of ovarian cancer cells but also alters pre-metastatic niche for ovarian cancer cell metastatic colonization, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic. Florence of Italy, from June 20th to 23rd,2015.
Chan D.W., MAK S.L. and Ngan H.Y.S., Role of Has-miR-141 as a therapeutic target and predictive biomarker for ovarian cancer, Cold Spring Harbour Asia-Precision Cancer Biology and Medicine. 2015.
Cheung A.N.Y., Guan X. and Ngan H.Y.S., Cervical cancer screening by enhanced cytology: application of novel markers, Hong Kong Med J. 2014.
Cheung A.N.Y., Wong G.W., Chan K.K., Yang M.S., Tsang C.H., Ji S.L., Lo C.K., Szeto E., Wong E.S.Y. and Ngan H.Y.S., Integrated human papillomavirus analysis as an adjunct for triage of atypical cervical cytology, In: ANY Cheung, OG Wong, KKY Chan, MS Yang, CH Tsang, SL Ji, CK Lo, E Szeto, E Wong, HYS Ngan, Hong Kong Med J. 2014.
JIANG Y., Siu K.Y., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Pyruvate dehydrogenase kinase 1 (PDHK1) regulates ovarian cancer cell migration, invasion, and chemoresistance and contributes to poor prognosis in patients, EACR-AACR-SIC Special Conference; 20-23 June 2015; Florence, Italy. Abstract no. 152. 2015.
LEUNG T.W., Liu S., Leung C.Y., Chu M.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis., J Med Virol.. 2015, 2015 Jun;87(6):1022-33..
LIANG R., Ngan H.Y.S. and Chan D.W., BCL2A1 Plays a Biphasic Role in Ovarian Cancer Progression, 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.
LIU J., Ngan H.Y.S. and Chan D.W., Identification of cisplatin-resistance related genes in Ovarian clear cell carcinoma using 3D cell culture model., 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.
LIU J., Ngan H.Y.S. and Chan D.W., Identification of cisplatin-resistance related genes in ovarian clear cell carcinoma using 3D cell culture system, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic held in Florence of Italy, from June 20th to 23rd, 2015.
Lee E.Y.P., YU X., Chu M.M.Y., Ngan H.Y.S., Siu S.W.K., Soong I.S., Chan Q. and Khong P.L., Perfusion and diffusion characteristics of cervical cancer based on intraxovel incoherent motion MR imaging-a pilot study , European Radiology. 2014, 24(7): 1506-1513.
Leung T.W., Liu S., Leung C.Y., Chu M.Y.M., Cheung A.N.Y. and Ngan H.Y.S., HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis, Journal of Medical Virology. 2015, 87: 1022-1033.
Liu S., Chan Y.K., Leung C.Y., Yip M.W., Lau S.K., Liao X.Y., Jiang L.L., Luk M.H.M., Lo S.S., Cheung A.N.Y., Lin Z.Q. and Ngan H.Y.S., Human papillomavirus status in southern Chinese women, Hong Kong Med J. 2014, 2014;20(Suppl 6):S35-8.
Mangili G., Lorusso D., Brown J., Pfisterer J., Massuger L., Vaughan M., Ngan H.Y.S., Golfier F., Sekharan P.K., Charry R.C., Poveda A., Kim J.W., Xiang Y., Berkowtiz R. and Seckl M.J., Trophoblastic disease review for diagnosis and management: a joint report from the International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup, Int J Gynecol Cancer. 2014, 24(9 Suppl 3): S109-16.
Ngan H.Y.S., AMP-activated protein kinase (AMPK) modulation as a potential therapeutic target for ovarian cancers, 2015 SNUCRI Cancer Symposium, Seoul, Korea, April 1-4. 2015.
Ngan H.Y.S., Cervical Cancer - (1) Overview: Epidemiology, Prevention, Screening, Diagnosis (2) Treatment, 2nd Joint Meeting of International Cancer Imaging Society & Hong Kong College of Radiologists, Hong Kong, February 1. 2015.
Ngan H.Y.S., Editorial Board Member - Journal of Clinical Oncology (Chinese Edition) since 2000. 2015.
Ngan H.Y.S., Editorial Board Member - Journal of Medical Association of Thailand. 2015.
Ngan H.Y.S., Editorial Board Member - Journal of Obstetrics and Gynaecology Research since 1997. 2015.
Ngan H.Y.S., Editorial Board Member - Journal of Paediatrics, Gynaecology and Obstetrics since 1997. 2015.
Ngan H.Y.S., Editorial Board Member - The Hong Kong Medical Journal. 2015.
Ngan H.Y.S., Editorial Board Member of 实用婦產科雜誌(編委). 2015.
Ngan H.Y.S., Editorial Member - 中華婦產科雜誌. 2015.
Ngan H.Y.S., Editorial Member - 國際婦產科學雜誌第七屆編輯委員會. 2015.
Ngan H.Y.S., Keynote speaker in plenary session “Robotic Assisted Laparoscopic Surgery in Gynecologic Cancers – Adoption in HK”, 12th Military Academic Congress of Obstetrics & Gynaecology, Xian, China, August 8-9. 2014.
Ngan H.Y.S., Robotic Assisted Laparoscopic Surgery inGynaecological Cancers – our experience , The Scientific Committee of the Obstetrics & Gynaecology Conference 2014 (International Lecture Series I), Matilda International Hospital, October 5. 2014.
Ngan H.Y.S., Robotic Surgery in Gynaecology Oncology, Red House Forum of the 3rd International Obstetrics & Gynecology Peak Forum, Shanghai, China, June 20-21, 2015.
Ngan H.Y.S., 卵巢生殖細胞腫瘤治療進展, The 5th Ovarian Cancer South China Summit, Shenzhen, 29 Nov. 中華醫學會婦產科腫瘤學分會卵巢癌專題研討會暨第五屆華南卵巢癌高峰論壇, 2014.
Ngan H.Y.S., The value and opportunities of HPV vaccines, 21st World Congress on Controversies in Obs, Gyn & Infertility (COGI), Guilin, China, March 8. 2015.
Ngan H.Y.S., Updates in cervical cancer prevention and control, 3rd Asian Society of Gynecologic Oncology (ASGO) Workshop, Seoul, Korea, August 22-23. 2014.
Ngan H.Y.S., Updates on trophoblastic neoplasia, The 2014 General Assembly and Annual Meeting of AGOG, Melbourne, Australia, Nov 8. 2014.
Pang T.K.R., Leung O.N., Ngan H.Y.S. and Yeung W.S.B., miR-135a induced formation of cancer-initialing cell subpopulation in cervical cancer, EMBO Conference Stem Cells in Cancer and Regenerative Medicine. 2014, 130.
Siu K.Y., JIANG Y., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Overexpression of Hexokinase 2 (HK2) in ovarian cancer contributes to cell migration, invasion and cancer stem-like cells regulation and correlates with poor patient survival., EACR-AACR-SIC Special Conference; 20-23 June 2015; Florence, Italy. Abstract no. 144. 2015.
TANG W.M., Ngan H.Y.S. and Chan D.W., The chemokines GRO-α and IL-8 secreted form omentum promotes aggressiveness of ovarian cancer cells, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic held in Florence of Italy, from June 20th to 23rd, 2015.. 2015.
TANG W.M., Ngan H.Y.S. and Chan D.W., The significance of Gro-α in modulating omental metastasis of ovarian cancer cells, 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.
Tse K.Y. and Ngan H.Y.S., The role of laparoscopy in staging of different gynaecological cancers, Best Pract Res Clin Obstet Gynaecol. . 2015, S1521-6934(15)00030-9.
Zhao F., Siu K.Y., Jiang L.L., Tam K.F., Ngan H.Y.S., Le X.F., Wong G.W., Wong E.S.Y., Gomes A.R., Bella L., Khongkow P., Lam E.W. and Cheung A.N.Y., Overexpression of Forkhead Box Protein M1 (FOXM1) in Ovarian Cancer Correlates with Poor Patient Survival and Contributes to Paclitaxel Resistance, PLoS ONE. 2014, 9: e113478.


Researcher : Ngu SF

Project Title:Clinical significance of JAG1/NOTCH1 signaling in cisplatin-resistance of ovarian clear cell carcinoma
Investigator(s):Ngu SF, Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


List of Research Outputs

Cheung K.W., Ngu S.F. and Cheung V.Y.T., Sonographic Characteristics Of The Uterus In Asymptomatic Women After Second-trimester Medical Termination Of Pregnancy, J Ultrasound Med. 2015, 34(4): 611-6.
Lui M.W.E., Ngu S.F. and Cheung V.Y.T., Mullerian cyst of the uterus misdiagnosed as ovarian cyst on pelvic sonography, J Clin Ultrasound. 2014, 42(3): 183-184.
Ngai F.W. and Ngu S.F., Predictors Of Family And Marital Functioning At Early Postpartum, J Adv Nurs. 2014, 70(11): 2588-97.
Ngai F.W. and Ngu S.F., Predictors Of Maternal And Paternal Depressive Symptoms At Postpartum, J Psychosom Res. 2015, 78(2): 156-61.
Ngu S.F., Common Gynaecological Malignancies: Management and Early Detection, Department of Family Medicine & Primary Healthcare (HKWC). 2014.
Ngu S.F., Refresher Course for Accredited Colposcopists, The Hong Kong Society of Colposcopy and Cervical Pathology. 2014.
Ngu S.F., Relationship of HPV and cervical premalignant conditions, The Cervical Smear Taker Course, The Family Planning Association of Hong Kong. 2015.


Researcher : O WS

List of Research Outputs

Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Mifepristone, but not levonorgestrel, has suppressive effect on tubal function at pharmacological dose which may contribute to emergency contraceptive action, 47th Annual Meeting of the Society for the Study of Reproduction. 2014.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function, Human Reproduction. 2014, 29: 2156-2162.


Researcher : Ong CYT

Project Title:To determine the correlation of changes in maternal levels of pregnancy-associated plasma protein A (PAPP-A) and free [beta] human chorionic gonadotrophin (F[beta]-hCG) with placental development and fetal outcomes
Investigator(s):Ong CYT, Lao TTH, Leung WC, Leung KY, Lam HSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:First trimester prediction of fetal α-thalassaemia-1 with maternal serum markers, nuchal translucency measurement and three dimentional ultrasound measurement of placental volume
Investigator(s):Ong CYT, Chen M, Leung KY, Tang MHY, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Maternal serum level of ADAM 12 as an early marker of trisomy 21, trisomy 13 and trisomy 18
Investigator(s):Ong CYT, Lee CP, Lau ETK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2007




Researcher : Pang RTK

Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang TKR, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007


List of Research Outputs



Researcher : Pang TKR

Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang TKR, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007


List of Research Outputs

Pang T.K.R., Leung O.N., YUEN C.K. and Yeung W.S.B., MicroRNA-135a induced formation of CD133+ cell sub-population with cancer-initiating cell properties in cervical cancer, 15th Society of Chinese Bioscientists in America International Symposium. Taiwan, 2015.
Pang T.K.R., Leung O.N., Ngan H.Y.S. and Yeung W.S.B., miR-135a induced formation of cancer-initialing cell subpopulation in cervical cancer, EMBO Conference Stem Cells in Cancer and Regenerative Medicine. 2014, 130.
Ye T., Pang T.K.R., Leung O.N., Chiu J.F. and Yeung W.S.B., Two-dimensional liquid chromatography with tandem mass spectrometry-based proteomic characterization of endometrial luminal epithelial surface proteins responsible for embryo implantation., In: Craig Niederberger, MD, Chicago, Illinois, USA Antonio Pellicer, MD, Valencia, Spain, Fertility and Sterility. USA, Elsevier, 2015, 103: 853-61e3.


Researcher : Shek NWM

List of Research Outputs

Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality – A new condition identified by exome sequencing? , Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 206.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014.


Researcher : Siu KY

Project Title:Effects of folate and folate receptor on ovarian and endometrial cancer: an in vitro study
Investigator(s):Siu KY, Cheung ANY
Department:Pathology
Source(s) of Funding:American Institute for Cancer Research (AICR) - General Award
Start Date:07/2006


Project Title:p21-activated kinase 4: a prognostic and therapeutic target for ovarian carcinoma?
Investigator(s):Siu KY, Cheung ANY, Ngan HYS
Department:Pathology
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:10/2007


List of Research Outputs

Ho J., DU Y., Wong G.W., Siu K.Y., Chan K.K.L. and Cheung A.N.Y., Downregulation of the Gli Transcription Factors Regulator Kif7 Facilitates Cell Survival and Migration of Choriocarcinoma Cells, PLoS ONE. 2014, 9: e108248.
JIANG Y., Siu K.Y., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Pyruvate dehydrogenase kinase 1 (PDHK1) regulates ovarian cancer cell migration, invasion, and chemoresistance and contributes to poor prognosis in patients, EACR-AACR-SIC Special Conference; 20-23 June 2015; Florence, Italy. Abstract no. 152. 2015.
Siu K.Y., JIANG Y., Cheung A.N.Y., Ngan H.Y.S. and Chan K.K.L., Overexpression of Hexokinase 2 (HK2) in ovarian cancer contributes to cell migration, invasion and cancer stem-like cells regulation and correlates with poor patient survival., EACR-AACR-SIC Special Conference; 20-23 June 2015; Florence, Italy. Abstract no. 144. 2015.
Zhao F., Siu K.Y., Jiang L.L., Tam K.F., Ngan H.Y.S., Le X.F., Wong G.W., Wong E.S.Y., Gomes A.R., Bella L., Khongkow P., Lam E.W. and Cheung A.N.Y., Overexpression of Forkhead Box Protein M1 (FOXM1) in Ovarian Cancer Correlates with Poor Patient Survival and Contributes to Paclitaxel Resistance, PLoS ONE. 2014, 9: e113478.


Researcher : So KH

List of Research Outputs

Kottawatta S.A., So K.H., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., OP3. The 3’-UTR of olfactomedin-1 and C-terminal binding protein-1 contain miR-212 regulatory sequence responsible for hCG regulation in human endometrial cells, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
So K.H., Kodithuwakku S.P., Li R.H.W., Chiu C.N., Cheung A.N.Y., Yeung W.S.B. and Lee C.K.F., Embryonic derived hCG down-regulates olfactomedin-1 thrgouh microRNA-212 in tubal ectopic pregnancy. P10, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.


Researcher : TANG WM

List of Research Outputs

CAI C., Shi L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling , 2014.
CAI C., SHI L., Liu V.W.S., TANG W.M., LIU J., Leung T.H.Y., Chan K.K.L., Yam J.W.P., Yao K.M., Ngan H.Y.S. and Chan D.W., Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling, Oncotarget. USA, Impact Journals, LLC., 2014, 5: 7549-62.
TANG W.M., Ngan H.Y.S. and Chan D.W., The chemokines GRO-α and IL-8 secreted form omentum promotes aggressiveness of ovarian cancer cells, EACR-AACR-SIC Special Conference on Anticancer Drug Action and Drug Resistance: from Cancer Biology to the Clinic held in Florence of Italy, from June 20th to 23rd, 2015.. 2015.
TANG W.M., Ngan H.Y.S. and Chan D.W., The significance of Gro-α in modulating omental metastasis of ovarian cancer cells, 19th RPG Symposium, Faculty of Medicine, HKU. 10-11 Dec 2014.


Researcher : Tam KF

List of Research Outputs

Zhao F., Siu K.Y., Jiang L.L., Tam K.F., Ngan H.Y.S., Le X.F., Wong G.W., Wong E.S.Y., Gomes A.R., Bella L., Khongkow P., Lam E.W. and Cheung A.N.Y., Overexpression of Forkhead Box Protein M1 (FOXM1) in Ovarian Cancer Correlates with Poor Patient Survival and Contributes to Paclitaxel Resistance, PLoS ONE. 2014, 9: e113478.


Researcher : Tang FOS

Project Title:A prospective randomized comparison of sublingual and vaginal misoprostol in termination of pregnancy in the second trimester
Investigator(s):Tang FOS, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:10/2000




Researcher : Tang GWK

Project Title:A cross sectional health care study of Chinese perimenopausal women in Hong Kong
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:01/1993


List of Research Outputs

Li R.H.W., Cheung C.L., Tan K.C.B., Sham P.C., Kung A.W.C. and Tang G.W.K., Replication study of genetic loci influencing age at menopause in Southern Chinese women., The 10th European Congress on Menopause and Andropause, Madrid, May 2015.
Tang G.W.K., 35 year Long Service Award, HKU 2015. 2015.
Tang G.W.K., Adviser of Editorial Board, The Hong Kong College of Family Physicians, 2015.


Researcher : Tang MHY

List of Research Outputs

Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629.
Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014.
YEUNG K.S., Chee W.Y.Y., Luk H.M., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Shuen A.Y., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Spread of X Inactivation on Chromosome 15 is Associated with a More Severe Phenotype in a Girl with an Unbalanced t(X;15) Translocation, American Journal of Medical Genetics (Part A). 2014, 164(10): 2521-2528.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality – A new condition identified by exome sequencing? , Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 206.
Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014.


Researcher : Tang WF

List of Research Outputs

Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629.


Researcher : Tse KY

List of Research Outputs

Lee E.Y.P., Hui S.K., Chan K.K.L., Tse K.Y., Kwong W.K.P., Chang T.Y., Chan Q. and Khong P.L., Relationship between intravoxel incoherent motion diffusion-weighted MRI and dynamic contrast-enhanced MRI in tissue perfusion of cervical cancers, Journal of Magnetic Resonance Imaging. 2014, n/a-n/a.


Researcher : WANG Y

List of Research Outputs

Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, In: Department of Obstetrics and Gynaecology, CUHK, Symposium on Male Infertility, The Chinese University of Hong Kong, Hong Kong, 27 August 2014. 2014.


Researcher : WONG CW

List of Research Outputs

WONG C.W., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., IBSA poster prize: The roles of ERp57 and surface thiol/disulphide exchange in spermatozoa-zona pellucida binding , In: European Academy of Andrology, 8th European Congress of Andrology, Barcelona, Spain . 2014.


Researcher : Wan HLT

List of Research Outputs

Wan H.L.T., Hui P.W., Li R.H.W. and Ng E.H.Y., Obstetric outcomes in women with polycystic ovary syndrome and isolated polycystic ovaries undergoing in vitro fertilization: a retrospective cohort analysis, Journal of Maternal and Fetal Neonatal Medicine. 2015, 28: 475-478.


Researcher : Wang Q

List of Research Outputs

Wang Q., Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C., Ng E.H.Y. and Ho P.C., Preimplantation genetic diagnosis using combined strategies on a breast cancer patient with a novel genomic deletion in BRCA2, Journal of Assisted Reproduction and Genetics . 2014, 31(12): 1719-1726.


Researcher : Wong CK

List of Research Outputs

Li T.K.T., Li Y.X., Li R.H.W., Yeung T.T., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The endocrine disruptor perflurooctanesulfonate (PFOS) modulates embryo implantation through Wnt/b-catenin inhibition. P06., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.


Researcher : XU S

List of Research Outputs

XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Regulatory Mechanism of Endometrial Mesenchymal-like Stem Cells during Menstruation, European Society of Human Reproduction and Embryology. 2015.


Researcher : Xiang L

List of Research Outputs

Xiang L., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Slow-cycling mesenchymal stromal cells in human endometrium possess common hallmark somatic stem cell properties, Stem Cell Research & Therapy. 2014, 5: 84.


Researcher : YUEN CK

List of Research Outputs

Pang T.K.R., Leung O.N., YUEN C.K. and Yeung W.S.B., MicroRNA-135a induced formation of CD133+ cell sub-population with cancer-initiating cell properties in cervical cancer, 15th Society of Chinese Bioscientists in America International Symposium. Taiwan, 2015.


Researcher : Ye T

List of Research Outputs

Ye T., Pang T.K.R., Leung O.N., Chiu J.F. and Yeung W.S.B., Two-dimensional liquid chromatography with tandem mass spectrometry-based proteomic characterization of endometrial luminal epithelial surface proteins responsible for embryo implantation., In: Craig Niederberger, MD, Chicago, Illinois, USA Antonio Pellicer, MD, Valencia, Spain, Fertility and Sterility. USA, Elsevier, 2015, 103: 853-61e3.


Researcher : Yeung TWY

List of Research Outputs

Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome., Human Reproduction. 2015, 30(9): 2178-2183.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., A randomized, controlled, pilot trial on the effect of dehydroepiandrosterone on ovarian response markers, ovarian response, and in vitro fertilization outcomes in poor responders, Fertility and Sterility. 2014, 102: 108-115.e1.
Yeung T.W.Y., Chai J., Li R.H.W., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Reply: Endometrial injury and reproductive outcomes: there's more to this story than meets the horse's blind eye, Human Reproduction. 2015, 3: 749-750.


Researcher : Yeung WSB

Project Title:MicroRNA-135a transforms normal HPV infected cervical cells into cancer cells and cells with cancer stem cell-like properties
Investigator(s):Yeung WSB, Tsao GSW, Ngan HYS, Pang TKR, Cheung ANY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Identification and characterization of label-retaining cells in cervical cancer
Investigator(s):Yeung WSB, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014


Project Title:The conserved functions of let-7 in embryonic diapause
Investigator(s):Yeung WSB, Liu W, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2015


Project Title:A study on the effect of targeted DNA methylation of PDX-1 on pancreatic lineage differentiation of human embryonic stem cells
Investigator(s):Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2015


List of Research Outputs

CAO M., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Label Retaining Stromal Cells Are Involved in Uterine Remodeling after Parturition., World Congress of Reproductive Biology. 2014.
CHEN C.H., Lee C.Y.L., Fong S.W. and Yeung W.S.B., Hyperglycemia impedes hESC differentiation into definitive endoderm through modulation of histone methylation patterns, International Society of Stem Cell Research 2015.
Chiu C.N., WANG Y., HUANG W., Lee C.L., Lam K.W. and Yeung W.S.B., Complementary role of sperm sialyl-Lewis(x) binding proteins and sialidase on sperm-zona pellucida interaction in human, In: Department of Obstetrics and Gynaecology, CUHK, Symposium on Male Infertility, The Chinese University of Hong Kong, Hong Kong, 27 August 2014. 2014.
Chiu C.N., Lam K.K., Wong R.C. and Yeung W.S.B., The identity of zona pellucida receptor on spermatozoa: an unresolved issue in developmental biology, Semin Cell Dev Biol.. 2014, 30: 86-95.
Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C.Y., Ng E.H.Y. and Ho P.C., Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage, Reprod Biol Endocrinol. 2014, 12: 105.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau E.Y.L., Ho P.C. and Ng E.H.Y., Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre, Hong Kong Medical Journal. 2015, 21(4): 299-303.
Ko K.Y.J., HUANG W., Li R.H.W., Yeung W.S.B., Ho P.C. and Chiu C.N., An in vitro study of the effect of mifepristone and ulipristal acetate on human sperm functions, Andrology. 2014, n/a-n/a.
Kodithuwakku S.P., Yeung W.S.B., Ho P.C. and Lee C.K.F., P263, Activation of canonical Wnt-signaling pathway, human chorionic gonadothrophin and progesterone may predispose fallopian tube epithelium to embryo attachment., Proceedings of the Peradeniya University International Research Sessions. 4-5 July 2014, Sri Lanka.. 2014.
Kottawatta S.A., So K.H., Ng E.H.Y., Yeung W.S.B. and Lee C.K.F., OP3. The 3’-UTR of olfactomedin-1 and C-terminal binding protein-1 contain miR-212 regulatory sequence responsible for hCG regulation in human endometrial cells, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Lam K.W., Li R.H.W., Ng E.H.Y., Ho P.C. and Yeung W.S.B., Semen analysis - what a clinician should know, Journal of Paediatrics, Obstetrics and Gynaecology. Singapore, 2015, Jan: 37-44.
Lee C.L., Yeung W.S.B. and Chiu C.N., Protective role of glycodelin-A on sperm motility during co-culture with macrophage, The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2014.
Lee C.Y.L., Fong S.W., CHEN C.H., LI T., Yeung W.S.B. and Lee C.K.F., A NOVEL HUMAN EMBRYONIC STEM CELL-DERIVED TROPHOBLASTIC SPHEROID IMPLANTATION MODEL FOR THE STUDY OF EARLY HUMAN IMPLANTATION, International Society Of Stem Cells Research Annual Meeting 2015.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Mifepristone, but not levonorgestrel, has suppressive effect on tubal function at pharmacological dose which may contribute to emergency contraceptive action, 47th Annual Meeting of the Society for the Study of Reproduction. 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian Response and Cumulative Live Birth Rate of Women Undergoing In-Vitro Fertilisation Who Had Discordant Anti-Mullerian Hormone and Antral Follicle Count Measurements: A Retrospective Study, PLoS ONE. 2014, 9: e108493.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count measurements: a retrospective study, The 21st World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI). 2015.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Ovarian response and cumulative live birth rate of women undergoing in-vitro fertilisation who had discordant anti-Mullerian hormone and antral follicle count, The 30th Annual Meeting of European Society of Human Reproduction and Embryology, Munich, Germany, June 29 – July 2, 2014 (poster presentation). 2014.
Li R.H.W., Lee V.C.Y., Lau E.Y.L., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Role of baseline antral follicle count and anti-Mullerian hormone in the index stimulation cycle of IVF treatment in predicting outcome of subsequent frozen-thawed embryo transfers, Gynecological Endocrinology. 2014, 30: 490-493.
Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome., Human Reproduction. 2015, 30(9): 2178-2183.
Li R.H.W., Liao S., Yeung W.S.B., Ng E.H.Y., O W.S. and Ho P.C., Ulipristal acetate resembles mifepristone in modulating human Fallopian tube function, Human Reproduction. 2014, 29: 2156-2162.
Li T.K.T., Li Y.X., Li R.H.W., Yeung T.T., Yeung W.S.B., Ng E.H.Y., Wong C.K. and Lee C.K.F., The endocrine disruptor perflurooctanesulfonate (PFOS) modulates embryo implantation through Wnt/b-catenin inhibition. P06., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Pang T.K.R., Leung O.N., YUEN C.K. and Yeung W.S.B., MicroRNA-135a induced formation of CD133+ cell sub-population with cancer-initiating cell properties in cervical cancer, 15th Society of Chinese Bioscientists in America International Symposium. Taiwan, 2015.
Pang T.K.R., Leung O.N., Ngan H.Y.S. and Yeung W.S.B., miR-135a induced formation of cancer-initialing cell subpopulation in cervical cancer, EMBO Conference Stem Cells in Cancer and Regenerative Medicine. 2014, 130.
So K.H., Kodithuwakku S.P., Li R.H.W., Chiu C.N., Cheung A.N.Y., Yeung W.S.B. and Lee C.K.F., Embryonic derived hCG down-regulates olfactomedin-1 thrgouh microRNA-212 in tubal ectopic pregnancy. P10, The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
Vijayan M., Lee C.L., Lee C.K.F., Yeung W.S.B. and Chiu C.N., Role of glycodelin A in modulating monocyte differentiation and immunomodulatory function of decidual macrophages. P11., The 31st Annual Scientific Meeting of HKSEMR. 9 Nov 2014, Hong Kong.. 2014.
WONG C.W., Lam K.W., Yeung W.S.B., Ho P.C. and Chiu C.N., IBSA poster prize: The roles of ERp57 and surface thiol/disulphide exchange in spermatozoa-zona pellucida binding , In: European Academy of Andrology, 8th European Congress of Andrology, Barcelona, Spain . 2014.
Wang Q., Chow J.F.C., Yeung W.S.B., Lau E.Y.L., Lee V.C., Ng E.H.Y. and Ho P.C., Preimplantation genetic diagnosis using combined strategies on a breast cancer patient with a novel genomic deletion in BRCA2, Journal of Assisted Reproduction and Genetics . 2014, 31(12): 1719-1726.
XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Regulatory Mechanism of Endometrial Mesenchymal-like Stem Cells during Menstruation, European Society of Human Reproduction and Embryology. 2015.
Xiang L., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Slow-cycling mesenchymal stromal cells in human endometrium possess common hallmark somatic stem cell properties, Stem Cell Research & Therapy. 2014, 5: 84.
Ye T., Pang T.K.R., Leung O.N., Chiu J.F. and Yeung W.S.B., Two-dimensional liquid chromatography with tandem mass spectrometry-based proteomic characterization of endometrial luminal epithelial surface proteins responsible for embryo implantation., In: Craig Niederberger, MD, Chicago, Illinois, USA Antonio Pellicer, MD, Valencia, Spain, Fertility and Sterility. USA, Elsevier, 2015, 103: 853-61e3.
Yeung W.S.B., 单基因植入前遗传诊断, National CME Symposium in Obstetrics and Gynaecology, Frontiers In Assisted Reproduction and Reproductive Genetics, October 31-November 2, 2014, Organizers: The University of Hong Kong and The University of Hong Kong, Shenzhen Hospital. 2014.


Researcher : Yip MW

List of Research Outputs

Liu S., Chan Y.K., Leung C.Y., Yip M.W., Lau S.K., Liao X.Y., Jiang L.L., Luk M.H.M., Lo S.S., Cheung A.N.Y., Lin Z.Q. and Ngan H.Y.S., Human papillomavirus status in southern Chinese women, Hong Kong Med J. 2014, 2014;20(Suppl 6):S35-8.


Researcher : Yung SF

Project Title:A randomized comparative trial to compare the efficacy of vaginal misoprostol moistened with 5% acetic acid with dry vaginal misoprostol in the medical management of first trimester silent miscarriage
Investigator(s):Yung SF, Ho PC, Ng EHY, Lee VCY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2011
Completion Date:11/2014


Project Title:Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps
Investigator(s):Yung SF, Lee CKF, Ng EHY, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2013




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