DEPT OF ANAESTHESIOLOGY



Researcher : Cheung CW

Project Title:Implantation of intrathecal pump for cancer pain patients
Investigator(s):Cheung CW, Tsang JWH
Department:Anaesthesiology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2012


Project Title:Central Administration of ETAR Antagonist BQ-123 Ameliorate Mechanical Allodynia in Rats Using a Sciatic Nerve Ligation Model
Investigator(s):Cheung CW, Ng JKF
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:03/2013


Project Title:Cash donation to support service and clinical research (Pain Management)
Investigator(s):Cheung CW, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:Cash donation for supporting service and clinical research
Start Date:11/2013


Project Title:CXCL12/CXCR4 chemokine signaling in astrocytes following noxious stimulation
Investigator(s):Cheung CW, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:01/2014


Project Title:Central CXCL12/CXCR4 axis contributes to the induction of peripheral neuropathic pain
Investigator(s):Cheung CW, Irwin MG, Wong SCS
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:01/2015


List of Research Outputs

Au A.H., Choi S.W., Cheung C.W. and Leung M.Y.Y., The Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis., PLoS One. 2015, 10: e0127611.
Au A.H., Choi S.W., Cheung C.W. and Leung Y.Y., he Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis., In: Au AH, Choi SW, Cheung CW, Leung YY, PLOS One. 2015.
Cheung C.W., Chronic Opioid Therapy in Chronic Pain Patients: What do we need? , AGM and Annual Scientific Symposium, 2nd December 2014, Hong Kong.. 2014.
Cheung C.W., QIU Q., Choi S.W., Moore B.J., Goucke C.R. and Irwin M.G., Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines, Pain Physician 2014. In press. 2014.
Cheung C.W., Conscious Sedation in the EP laboratory, CardioRhythm 2015, 1st February 2015, Hong Kong.. 2015.
Cheung C.W., Wang J.S., Choo C.Y., KIm Y.C., Lin F.S., Moon S.H., Osio-Salido E., Pan S.F., Singh V.A., Yoon S.H., Ward L., Bahadur N. and Bhagat A., Current Practices of chronic non-cancer pain management: Physicians' perspectives from a Pan Asian Survey., 15th World Congress on Pain, Buenos Aires, Argentina. 6-11 October 2014.
Cheung C.W., Founding the Pain Fellowship Training in Hong Kong, Founding the Pain Fellowship Training in Hong Kong. 2015.
Cheung C.W., QIU Q., Liu J.T.C., Chu K.M. and Irwin M.G., Intranasal dexmedetomidine in combination with patient-controlled sedation during upper gastrointestinal endoscopy: a randomised trial, Acta Anaesthesiologica Scandinavica. 2015, 59: 215-223.
Cheung C.W., Peer Reviewer, Annals, Academy of Medicine, Singapore. 2015.
Cheung C.W., Peer Reviewer, Annals, Academy of Medicine, Singapore. 2015.
Cheung C.W., Peer Reviewer, BMC Anesthesiology . 2015.
Cheung C.W., Peer Reviewer, Clinical Neuropharmacology. 2015.
Cheung C.W., Peer Reviewer, Cochrane Review. 2015.
Cheung C.W., Peer Reviewer, Cochrane Review. 2015.
Cheung C.W., Peer Reviewer, Current Medical Research and Opinion. 2015.
Cheung C.W., Peer Reviewer, Medicine. 2015.
Cheung C.W., Peer Reviewer, PLoS One. 2015.
Cheung C.W., Peer Reviewer, World Journal of Anesthesiology. 2015.
Cheung C.W., Perioperative Pain Management, Combined Scientific Meeting of the Oriental Congress of Anaesthesiology and Preoperative Medicine (OCAP 2015) & International Federation of Societies of Intravenous Anaesthesia (IFIVA 2015), 19th-21st June, 2015, Shanghai.. 2015.
Cheung C.W., Principles of Use of Strong Opioids in Chronic Non-cancer Pain, The 2014 Chinese Society of Anesthesiologists (CSA) Annual Meeting. 2014.
Cheung C.W., Speaker, Endothelin-1 and Neuropathic Pain., 臨床麻醉知識更新學習班暨學術研討會. 25-28 July 2014. 河南開封, 中國.. 2014.
Cheung C.W., Speaker, 麻醉科管理香港經驗分享, 廣東省醫院協會麻醉管理專業委員會暨廣州國際麻醉科管理高峰論壇. 5th July 2014. 廣州中國.. 2014.
Cheung C.W., LUO X., TAI W.L., Hung K.L., Chung S.K. and Xiao M.W., Targeted over-expression of astrocytic endothelin-1 attenuates neuropathic pain by up-regulating spinal excitatory amino acid transporter-2, In: Victor KL Hung, Lydia W Tai1, Xin Luo, Xiao Min Wang, Sookja K Chung and Chi Wai Cheung, Journal of Molecular Neuroscience. 2015, 2015 (In Press).
Cheung C.W., Use of Opioids in Cancer Pain Management, 21st Hong Kong International Cancer Congress. 2014.
Cheung C.W., Vocational Training in Anaesthesiology in Hong Kong, 2014 Congress of Shanghai Association of Anesthesiologists (CSAA2014), 28th to 30th November, 2014. 2014.
Cheung C.W., 港台口腔門診靜脈鎮靜麻醉培訓經驗, 兩岸三地口腔門診靜脈鎮靜麻醉研討會, Tai Chung, Taiwan, 25th January 2015.. 2015.
Cheung C.W., 脊髓電刺治療慢性腰痛, Chinese Society of Integrative Anesthesiology, 26th-28th June, 2015, Shandong, China. 2015.
Irwin M.G., Cheung C.W. and Wong G.T.C., Conscious sedation for surgical procedures, In: MG Irwin and GTC Wong, Dexmedetomidine: handbook of clinical applications (second edition). 2015.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central Cxcl12/cxcr4 Axis Contributes To The Pain Induction In A Mouse Model Of Complex Regional Pain Syndrome-type I, International Anesthesia Research Society 2015 Annual Meeting And International Science Symposium. 2015.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central administration of C-x-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice, PLoS One. 2014, 9(8): e104860.
Li Q., Chen Y.M., LUO X., Ko J.K.S., Hu Y.G. and Cheung C.W., Synthesis and biological activity of fused furo[2,3-d] pyrimidinone derivate as analgesic and antitumor agent., In: Li Qing, Chen Yong Mei, Luo Xin, Ko Joshua Ka Shun, Hu Yang Gen, Cheung Chi Wai, Research on Chemical Intermediates. 2015.
Liman S., Cheung C.W., Wong K., TAI W.L., QIU Q., Ng J.K.F., Choi S.W. and Irwin M.G., Preventive Treatment with Ketamine attenuates the ischaemia-reperfusion response in a chronic postichaemia pain model, Oxid Med Cell Longev. 2015, 2015: 380403.
Osio Salido E., Singh V.A., Wang J.S., Cheung C.W., Choo C.Y., Kim Y.C., Lin F.S., Moon S.H., Pan S.F., Yoon S.H., Ward L., Bahadur N. and Bhagat A., Patients' Perspectives on chronic non-cancer pain management in Asia., 15th World Congress on Pain, Buenos Aires, Argentina. 6-11 October 2014.. 2014.
Sun L.T., TAI W.L., QIU Q., LUO X., MITCHELL R., FLEETWOOD-WALKER S. and Cheung C.W., Role Of Endocannabinoids In Epidural Spinal Cord Stimulation-induced Analgesia In Rats. , The Combined Scientific Meeting Of The Oriental Congress Of Anesthesiology And Perioperative Medicine (ocap 2015) & International Federation Of Societies Of Intravenous Anaesthesia (ifiva 2015). 2015.
TAI W.L., Sun L.T., PAN Z., QIU Q. and Cheung C.W., Inhibition Of Spinal Endothelin Type A Receptor Ameliorates Neuropathic Pain Through Down-regulation Of Mapk And Nf--κb P65 In Rats, 2015.
Tsui P.Y., Cheung C.W., Lee Y., Leung S.W.S. and Ng J.K.F., The effectiveness of low-dose desmopressin in improving hypothermia-induced impairment of primary haemostasis under influence of aspirin - a randomized controlled trial., BMC Anesthesiol. 2015, 15: 80.
Wang X.M.A., Walitt B., Saligan L., Tiwari A.F.Y., Cheung C.W. and Zhang Z., Chemobrain: a critical review and causal hypothesis of link between cytokines and epigenetic reprogramming associated with chemotherapy, Cytokine. 2015, 72(1): 86-96.
Wong K., Wu Y.R., Cheng K.S., Chan P., Cheung C.W., Lu D.Y., Su T.H., Liu Z.M. and King Y.M., Palmitic acid-induced lipotoxicity and protection by (+)- catechin in rat cortical astrocytes, Pharmacological reports 2014. In press. 2014.
Wong K., Cheung C.W., Chao C.Z., SO E.C., Huang B.M. and Leung Y.M., The molecular mechanism of the anti-oxidative effects of tannic acid on palmitic acid-induced cytotoxicity in pneumocytes., 19th World Congress on Heart Disease, Boston, July 25-28 2014.
Wong K.L., Cheung C.W., Chao C.Z., So E.C., Huang B.M. and Leung Y.M., THE MOLECULAR MECHANISM OF THE ANTI-OXIDATIVE EFFECTS OF TANNIC ACID ON PALMITIC ACID-INDUCED CYTOTOXICITY IN PNEUMOCYTES, In: KL Wong, CW Cheung, CZ Chao, EC So, BM Huang, YM Leung, 19th World Congress on Heart Disease, Boston. 2014.
Xu J., LI H., Irwin M.G., Xia Z.Y., MAO X., Lei S., Wong G.T.C., Hung V., Cheung C.W., Fang X., Clanachan A.S. and Xia Z., Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Crit Care Med. 2014, 42(8): e583-94.


Researcher : Choi SW

List of Research Outputs

Au A.H., Choi S.W., Cheung C.W. and Leung M.Y.Y., The Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis., PLoS One. 2015, 10: e0127611.
Au A.H., Choi S.W., Cheung C.W. and Leung Y.Y., he Efficacy and Clinical Safety of Various Analgesic Combinations for Post-Operative Pain after Third Molar Surgery: A Systematic Review and Meta-Analysis., In: Au AH, Choi SW, Cheung CW, Leung YY, PLOS One. 2015.
Cheung C.W., QIU Q., Choi S.W., Moore B.J., Goucke C.R. and Irwin M.G., Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines, Pain Physician 2014. In press. 2014.
Liman S., Cheung C.W., Wong K., TAI W.L., QIU Q., Ng J.K.F., Choi S.W. and Irwin M.G., Preventive Treatment with Ketamine attenuates the ischaemia-reperfusion response in a chronic postichaemia pain model, Oxid Med Cell Longev. 2015, 2015: 380403.


Researcher : Chu MT

List of Research Outputs

Chu M.T., Lau C.F., Chang R.C.C. and Wong G.T.C., Exploring the potential impact of endurance exercise in Alzheimer’s disease, International Alzheimer’s Disease Conference 2015.
HUANG C., Ng T.W., Chu M.T., Chang R.C.C. and Wong G.T.C., Correlation between tau hyperphosphorylation and inflammation in post operative cognitive dysfunction, International Alzheimer’s Disease Conference 2015.
LEUNG W.Y.Y., Ng T.W., Chu M.T., Chang R.C.C. and Wong G.T.C., Investigating the modulatory effects of sevoflurane on systemic inflammation-induced cognitive dysfunction, International Alzheimer’s Disease Conference 2015.


Researcher : Goucke CR

List of Research Outputs

Cheung C.W., QIU Q., Choi S.W., Moore B.J., Goucke C.R. and Irwin M.G., Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines, Pain Physician 2014. In press. 2014.


Researcher : HUANG C

List of Research Outputs

HUANG C., Ng T.W., Chu M.T., Chang R.C.C. and Wong G.T.C., Correlation between tau hyperphosphorylation and inflammation in post operative cognitive dysfunction, International Alzheimer’s Disease Conference 2015.
HUANG C., Ho Y.S., Ng T.W., Irwin M.G., Chang R.C.C. and Wong G.T.C., Dexmedetomidine directly increases tau phosphorylation, Journal of Alzheimer's Disease. 2015, 44: 839-850.
Ng T.W., HUANG C., Lau C.F., Wong G.T.C. and Chang R.C.C., The potential impact of anaesthesia induced synaptic proteins changes on post-operative cognitive dysfunction (POCD), International Alzheimer’s Disease Conference 2015.


Researcher : Hung KL

List of Research Outputs

Cheung C.W., LUO X., TAI W.L., Hung K.L., Chung S.K. and Xiao M.W., Targeted over-expression of astrocytic endothelin-1 attenuates neuropathic pain by up-regulating spinal excitatory amino acid transporter-2, In: Victor KL Hung, Lydia W Tai1, Xin Luo, Xiao Min Wang, Sookja K Chung and Chi Wai Cheung, Journal of Molecular Neuroscience. 2015, 2015 (In Press).


Researcher : Irwin MG

Project Title:A comparative study of hydroxyethyl starch (130/0.4) and gelatin on the immune response in paediatric scoliosis surgery
Investigator(s):Irwin MG, Wylie SJ
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:01/2009


Project Title:Radiofrequency therapy for chronic and cancer pain patient
Investigator(s):Irwin MG, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:08/2010


Project Title:Effects of ketamine on the CGRP-CRLR ligand-receptor complex and pain signaling
Investigator(s):Irwin MG, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:05/2014


Project Title:The effect of over-expression of astrocytic ET-1 on Complex Regional Pain Syndrome I in a chronic post-ischaemia pain model.
Investigator(s):Irwin MG, Cheung CW, Wong SCS
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:03/2015


List of Research Outputs

Cheung C.W., QIU Q., Choi S.W., Moore B.J., Goucke C.R. and Irwin M.G., Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines, Pain Physician 2014. In press. 2014.
Cheung C.W., QIU Q., Liu J.T.C., Chu K.M. and Irwin M.G., Intranasal dexmedetomidine in combination with patient-controlled sedation during upper gastrointestinal endoscopy: a randomised trial, Acta Anaesthesiologica Scandinavica. 2015, 59: 215-223.
HUANG C., Ho Y.S., Ng T.W., Irwin M.G., Chang R.C.C. and Wong G.T.C., Dexmedetomidine directly increases tau phosphorylation, Journal of Alzheimer's Disease. 2015, 44: 839-850.
Irwin M.G., Advisory Board Member, Medical Grapevine. 2015.
Irwin M.G., Annual Scientific Meeting, Chengdu, China, Chinese Society of Anaesthetists. 2014.
Irwin M.G., Annual Scientific Meeting, UK, Association of Anaesthetists Great Britain and Ireland. 2014.
Irwin M.G., Board Member, Children's Surgical Centre Cambodia. 2015.
Irwin M.G., Board Member, Health Services Research Committee. 2015.
Irwin M.G., Chinese Society of Anaesthetists, Annual Scientific Meeting, Chengdu. 2014.
Irwin M.G., Cheung C.W. and Wong G.T.C., Conscious sedation for surgical procedures, In: MG Irwin and GTC Wong, Dexmedetomidine: handbook of clinical applications (second edition). 2015.
Irwin M.G., Editorial Board Member (Senior Editor), Hong Kong Medical Journal. 2015.
Irwin M.G., Editorial Board Member, Acta Anaesthesia Taiwancia. 2015.
Irwin M.G., Editorial Board Member, Anaesthesia. 2015.
Irwin M.G., Editorial Board Member, Anaesthesia & Intensive Care Medicine. 2015.
Irwin M.G., Editorial Board Member, CPD Anaesthesia (UK). 2015.
Irwin M.G., Editorial Board Member, Journal of International Medical Research. 2015.
Irwin M.G., Editorial Board Member, Opinion on Pharmacotherapy. 2015.
Irwin M.G., Editorial Board Member, Pain Research and Treatment. 2015.
Irwin M.G., Editorial Board Member, Perioperative Medicine. 2015.
Irwin M.G., Thompson J., Telford R. and Hoewell S., Foreword, Oxford textbook of Vascular Anaesthesia. 2015.
Irwin M.G., Member, HK Hospital Authority Expert Panel in Anaesthesiology. 2015.
Irwin M.G. and Wong G.T.C., Myocardial protection during cardiac surgery, In: R Peter Alston, Paul S. Myles and Marco Ranucci, Oxford Textbook of Cardiothoracic Anaesthesia. 2015.
Irwin M.G., Peer Revieweer, Anaesthesia and Intensive Care. 2015.
Irwin M.G., Peer Reviewer, Anaesthesia and Intensive Care. 2015.
Irwin M.G., Peer Reviewer, Anesthesia and Analgesia. 2015.
Irwin M.G., Peer Reviewer, Anesthesiology. 2015.
Irwin M.G., Peer Reviewer, Asean Journal of Anaesthesiology. 2015.
Irwin M.G., Peer Reviewer, British Journal of Anaesthesia. 2015.
Irwin M.G., Peer Reviewer, Canadian Journal of Anaesthesia. 2015.
Irwin M.G., Peer Reviewer, Canadian Journal of Physiolology & Pharmacology. 2015.
Irwin M.G., Peer Reviewer, Expert Opinion on Pharmacotherapy. 2015.
Irwin M.G., Peer Reviewer, Hong Kong Medical Journal. 2015.
Irwin M.G., Peer Reviewer, Journal of Clinical Anaesthesia. 2015.
Irwin M.G., Peer Reviewer, Journal of Molecular and Cellular Cardiology. 2015.
Irwin M.G., Peer Reviewer, Journal of Paediatrics, Obstetrics and Gynaecology. 2015.
Irwin M.G., Peer Reviewer, Journal of Pharmaceutical & Biomedical Analysis. 2015.
Irwin M.G., Peer Reviewer, Lancet. 2015.
Irwin M.G., Peer Reviewer, Medical science Monitor. 2015.
Irwin M.G., Peer Reviewer, Surgical Practice. 2015.
Irwin M.G., Peer reviewer, Anaesthesia. 2015.
Irwin M.G. and Kong K.F.V., Quantifying and communicating peri-operative risk, Anaesthesia. 2014, 69 (12): 1299-1303.
Irwin M.G. and Wong G.T.C., Remifentanil and Opioid-Induced Cardioprotection, Journal of Cardiothoracic and Vascular Anesthesia. 2015, 29: S23-S26.
Irwin M.G. and Gan T.J., Volume therapy with hydroxyethyl starches: are we throwing the anaesthesia baby out with the intensive care unit bathwater?, Anesth Analg. 2014 Sep. 2014, 119(3): 737-739.
LI H., Irwin M.G. and Xia Z., AHA International travel award, American Heart Association (AHA). 2014.
LI H., Irwin M.G. and Xia Z., Caveolin-3/AdipoR1 dependent mitochondrial STAT3 activation in ischemic postconditioning cardioprotection, Experimental Biology 2015. FASEB, 2015, 29(1):777.3: 777.3.
LI H., Irwin M.G. and Xia Z., Graduate Student Scientist Award, American Society of Pharmacology and Experimental Therapeutics (ASPET). 2015.
LI H., Irwin M.G. and Xia Z., Ischemic postconditioning confers cardioprotection through adiponectin-dependent mitochondrial STAT3 activation in mice, American Heart Association Scientific Sessions, Chicago, USA, 15-19 Nov, 2014.. 2014, Circulation, 2014, 130: A13879.
LI H., Yao W., Irwin M.G. and Xia Z., Propofol postconditioning confers hepatic protection via activating nrf2 in the early minutes of reperfusion which requires adiponectin in mice., IARS Annunal Meeting 2015. Anesth Analg 2015; 120;: S-154.
LI H., Tian Y., Liu P., Xu J.M., Irwin M.G., Tian G.G. and Xia Z., captopril pre-treatment produces additive cardioprotective effects to isoflurane preconditioning in attenuating myocardial ischemia reperfusion injury in rabbits and in humans, IARS Annunal Meeting. 2015, Anesth Analg 2015; 120.: S-34.
LIU Y., JIN J., LI H., Huang H., Irwin M.G. and Xia Z., nhibition of PKCβ2 Attenuates Myocardial Ischemia Reperfusion Injury in Diabetic Rat Through Cavolin-3-dependant Akt Activation, American Heart Association Annunal meeting. 2014, Circulation. 2014:130: A18247.
Li H., Yao W., Irwin M.G., Wang T., Wang S., Zhang T. and Xia Z., Adiponectin ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction by concomitantly activating Nrf2 and Brg1, Free Radic Biol Med. 2015, 84: 311-321.
Liman S., Cheung C.W., Wong K., TAI W.L., QIU Q., Ng J.K.F., Choi S.W. and Irwin M.G., Preventive Treatment with Ketamine attenuates the ischaemia-reperfusion response in a chronic postichaemia pain model, Oxid Med Cell Longev. 2015, 2015: 380403.
Liu Y., Jin J., Qiao S., Lei S., Liao S., Ge Z.D., Li H., Wong G.T.C., Irwin M.G. and Xia Z., Inhibition of PKCb2 overexpression ameliorates myocardial ischaemia/reperfusion injury in diabetic rats via restoring caveolin-3/Akt signaling, Clin Sci (Lond). 2015, 129(4): 331-344.
Luo C., Yuan D., Li X., Yao W., Luo G., Chi X., LI H., Irwin M.G., Xia Z. and Hei Z., Propofol attenuated acute kidney injury after orthotopic liver transplantation via inhibiting gap junction composed of connexion 32, Anesthesiology. 2015, 122(1): 72-86.
Xu J., LI H., Irwin M.G., Xia Z.Y., MAO X., Lei S., Wong G.T.C., Hung V., Cheung C.W., Fang X., Clanachan A.S. and Xia Z., Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Crit Care Med. 2014, 42(8): e583-94.


Researcher : JIN J

List of Research Outputs

LIU Y., JIN J., LI H., Huang H., Irwin M.G. and Xia Z., nhibition of PKCβ2 Attenuates Myocardial Ischemia Reperfusion Injury in Diabetic Rat Through Cavolin-3-dependant Akt Activation, American Heart Association Annunal meeting. 2014, Circulation. 2014:130: A18247.


Researcher : Jenkins CR

List of Research Outputs

Wong G.T.C., Jenkins C.R., Tsang J.W.H., Chen J.Y., Chan L.C. and Tanner J.A., Finalist for Best Free Communication , Asia Pacific Medical Education Conference. 2015.
Wong G.T.C., Jenkins C.R., Tsang J.W.H., Chen J.Y., Chan L.C. and Tanner J.A., Use of film to build student empathy and enable reflective thought in a new Medical Humanities programme embedded within the undergraduate MBBS curriculum., 12th Asia Pacific Medical Education Conference, Singapore (awarded Finalist prize in the Free Communication Session) (2015). 2015.
Wong G.T.C., Jenkins C.R., Tsang J.W.H., Chen J.Y., Chan L.C. and Tanner J.A., Use of film to build student empathy and enable reflective thought, Asia Pacific Medical Education Conference. 2015.


Researcher : Kong KFV

List of Research Outputs

Irwin M.G. and Kong K.F.V., Quantifying and communicating peri-operative risk, Anaesthesia. 2014, 69 (12): 1299-1303.


Researcher : LEUNG WYY

List of Research Outputs

LEUNG W.Y.Y., Ng T.W., Chu M.T., Chang R.C.C. and Wong G.T.C., Investigating the modulatory effects of sevoflurane on systemic inflammation-induced cognitive dysfunction, International Alzheimer’s Disease Conference 2015.


Researcher : LI H

List of Research Outputs

LI H., Irwin M.G. and Xia Z., AHA International travel award, American Heart Association (AHA). 2014.
LI H., Irwin M.G. and Xia Z., Caveolin-3/AdipoR1 dependent mitochondrial STAT3 activation in ischemic postconditioning cardioprotection, Experimental Biology 2015. FASEB, 2015, 29(1):777.3: 777.3.
LI H., Irwin M.G. and Xia Z., Graduate Student Scientist Award, American Society of Pharmacology and Experimental Therapeutics (ASPET). 2015.
LI H., Irwin M.G. and Xia Z., Ischemic postconditioning confers cardioprotection through adiponectin-dependent mitochondrial STAT3 activation in mice, American Heart Association Scientific Sessions, Chicago, USA, 15-19 Nov, 2014.. 2014, Circulation, 2014, 130: A13879.
LI H., Yao W., Irwin M.G. and Xia Z., Propofol postconditioning confers hepatic protection via activating nrf2 in the early minutes of reperfusion which requires adiponectin in mice., IARS Annunal Meeting 2015. Anesth Analg 2015; 120;: S-154.
LI H., Tian Y., Liu P., Xu J.M., Irwin M.G., Tian G.G. and Xia Z., captopril pre-treatment produces additive cardioprotective effects to isoflurane preconditioning in attenuating myocardial ischemia reperfusion injury in rabbits and in humans, IARS Annunal Meeting. 2015, Anesth Analg 2015; 120.: S-34.
LIU Y., JIN J., LI H., Huang H., Irwin M.G. and Xia Z., nhibition of PKCβ2 Attenuates Myocardial Ischemia Reperfusion Injury in Diabetic Rat Through Cavolin-3-dependant Akt Activation, American Heart Association Annunal meeting. 2014, Circulation. 2014:130: A18247.
Li T., Li J., LI H., Xia Z., Shi X., Li X. and Liu Y., [Effects of hypertonic sodium chloride hydroxyethyl starch solution on cerebral vasospasm following subarachnoid hemorrhage and its mechanism]., Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2014, 26(8): 589-93.
Wang L., Wu Z.Q., Liu S.M., LI H., Xia Z. and Huang H., Dexmedetomidine enhances cerebral cortex GIRK1 protein expression and attenuates Acute Postoperative Pain in rats, Experimental Biology 2015. FASEB J. 29:LB503: LB503.
Xu J., LI H., Irwin M.G., Xia Z.Y., MAO X., Lei S., Wong G.T.C., Hung V., Cheung C.W., Fang X., Clanachan A.S. and Xia Z., Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Crit Care Med. 2014, 42(8): e583-94.


Researcher : LIU Y

List of Research Outputs

LIU Y., JIN J., LI H., Huang H., Irwin M.G. and Xia Z., nhibition of PKCβ2 Attenuates Myocardial Ischemia Reperfusion Injury in Diabetic Rat Through Cavolin-3-dependant Akt Activation, American Heart Association Annunal meeting. 2014, Circulation. 2014:130: A18247.
Li T., Li J., LI H., Xia Z., Shi X., Li X. and Liu Y., [Effects of hypertonic sodium chloride hydroxyethyl starch solution on cerebral vasospasm following subarachnoid hemorrhage and its mechanism]., Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2014, 26(8): 589-93.


Researcher : LUO X

List of Research Outputs

Cheung C.W., LUO X., TAI W.L., Hung K.L., Chung S.K. and Xiao M.W., Targeted over-expression of astrocytic endothelin-1 attenuates neuropathic pain by up-regulating spinal excitatory amino acid transporter-2, In: Victor KL Hung, Lydia W Tai1, Xin Luo, Xiao Min Wang, Sookja K Chung and Chi Wai Cheung, Journal of Molecular Neuroscience. 2015, 2015 (In Press).
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central Cxcl12/cxcr4 Axis Contributes To The Pain Induction In A Mouse Model Of Complex Regional Pain Syndrome-type I, International Anesthesia Research Society 2015 Annual Meeting And International Science Symposium. 2015.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central administration of C-x-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice, PLoS One. 2014, 9(8): e104860.
Li Q., Chen Y.M., LUO X., Ko J.K.S., Hu Y.G. and Cheung C.W., Synthesis and biological activity of fused furo[2,3-d] pyrimidinone derivate as analgesic and antitumor agent., In: Li Qing, Chen Yong Mei, Luo Xin, Ko Joshua Ka Shun, Hu Yang Gen, Cheung Chi Wai, Research on Chemical Intermediates. 2015.
Sun L.T., TAI W.L., QIU Q., LUO X., MITCHELL R., FLEETWOOD-WALKER S. and Cheung C.W., Role Of Endocannabinoids In Epidural Spinal Cord Stimulation-induced Analgesia In Rats. , The Combined Scientific Meeting Of The Oriental Congress Of Anesthesiology And Perioperative Medicine (ocap 2015) & International Federation Of Societies Of Intravenous Anaesthesia (ifiva 2015). 2015.


Researcher : Lau CF

List of Research Outputs

Chu M.T., Lau C.F., Chang R.C.C. and Wong G.T.C., Exploring the potential impact of endurance exercise in Alzheimer’s disease, International Alzheimer’s Disease Conference 2015.
Ng T.W., HUANG C., Lau C.F., Wong G.T.C. and Chang R.C.C., The potential impact of anaesthesia induced synaptic proteins changes on post-operative cognitive dysfunction (POCD), International Alzheimer’s Disease Conference 2015.


Researcher : Lee Y

List of Research Outputs

Tsui P.Y., Cheung C.W., Lee Y., Leung S.W.S. and Ng J.K.F., The effectiveness of low-dose desmopressin in improving hypothermia-induced impairment of primary haemostasis under influence of aspirin - a randomized controlled trial., BMC Anesthesiol. 2015, 15: 80.


Researcher : Lei S

List of Research Outputs

Xu J., LI H., Irwin M.G., Xia Z.Y., MAO X., Lei S., Wong G.T.C., Hung V., Cheung C.W., Fang X., Clanachan A.S. and Xia Z., Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Crit Care Med. 2014, 42(8): e583-94.


Researcher : Leung KMM

List of Research Outputs

Cheung A.H.K., Li L.F., So V.C., Leung K.M.M. and Lui W.M., Transient monoplegia and paraesthesia after an epidural blood patch for a spinal cerebrospinal fluid leak, Clinical Neuroscience. 2015.


Researcher : Liu JTC

List of Research Outputs

Cheung C.W., QIU Q., Liu J.T.C., Chu K.M. and Irwin M.G., Intranasal dexmedetomidine in combination with patient-controlled sedation during upper gastrointestinal endoscopy: a randomised trial, Acta Anaesthesiologica Scandinavica. 2015, 59: 215-223.


Researcher : Liu Y

List of Research Outputs

LIU Y., JIN J., LI H., Huang H., Irwin M.G. and Xia Z., nhibition of PKCβ2 Attenuates Myocardial Ischemia Reperfusion Injury in Diabetic Rat Through Cavolin-3-dependant Akt Activation, American Heart Association Annunal meeting. 2014, Circulation. 2014:130: A18247.
Li T., Li J., LI H., Xia Z., Shi X., Li X. and Liu Y., [Effects of hypertonic sodium chloride hydroxyethyl starch solution on cerebral vasospasm following subarachnoid hemorrhage and its mechanism]., Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2014, 26(8): 589-93.


Researcher : MAO X

List of Research Outputs

Xu J., LI H., Irwin M.G., Xia Z.Y., MAO X., Lei S., Wong G.T.C., Hung V., Cheung C.W., Fang X., Clanachan A.S. and Xia Z., Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Crit Care Med. 2014, 42(8): e583-94.


Researcher : Moore BJ

List of Research Outputs

Cheung C.W., QIU Q., Choi S.W., Moore B.J., Goucke C.R. and Irwin M.G., Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines, Pain Physician 2014. In press. 2014.


Researcher : Ng JKF

Project Title:The role of endothelial arginine, arginase and nitric oxide on dexmedetomidine induced vascular contraction
Investigator(s):Ng JKF, Leung SWS
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2012


List of Research Outputs

Liman S., Cheung C.W., Wong K., TAI W.L., QIU Q., Ng J.K.F., Choi S.W. and Irwin M.G., Preventive Treatment with Ketamine attenuates the ischaemia-reperfusion response in a chronic postichaemia pain model, Oxid Med Cell Longev. 2015, 2015: 380403.
Tsui P.Y., Cheung C.W., Lee Y., Leung S.W.S. and Ng J.K.F., The effectiveness of low-dose desmopressin in improving hypothermia-induced impairment of primary haemostasis under influence of aspirin - a randomized controlled trial., BMC Anesthesiol. 2015, 15: 80.


Researcher : Ng TW

Project Title:Evaluating the effect of prostaglandin-E2 EP4 receptor signaling
Investigator(s):Ng TW, Chang RCC
Department:Anatomy
Source(s) of Funding:Small Project Funding
Start Date:04/2015


List of Research Outputs

LEUNG W.Y.Y., Ng T.W., Chu M.T., Chang R.C.C. and Wong G.T.C., Investigating the modulatory effects of sevoflurane on systemic inflammation-induced cognitive dysfunction, International Alzheimer’s Disease Conference 2015.


Researcher : QIU Q

List of Research Outputs

Cheung C.W., QIU Q., Choi S.W., Moore B.J., Goucke C.R. and Irwin M.G., Chronic opioid therapy for chronic non-cancer pain: a review and comparison of treatment guidelines, Pain Physician 2014. In press. 2014.
Cheung C.W., QIU Q., Liu J.T.C., Chu K.M. and Irwin M.G., Intranasal dexmedetomidine in combination with patient-controlled sedation during upper gastrointestinal endoscopy: a randomised trial, Acta Anaesthesiologica Scandinavica. 2015, 59: 215-223.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central Cxcl12/cxcr4 Axis Contributes To The Pain Induction In A Mouse Model Of Complex Regional Pain Syndrome-type I, International Anesthesia Research Society 2015 Annual Meeting And International Science Symposium. 2015.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central administration of C-x-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice, PLoS One. 2014, 9(8): e104860.
Liman S., Cheung C.W., Wong K., TAI W.L., QIU Q., Ng J.K.F., Choi S.W. and Irwin M.G., Preventive Treatment with Ketamine attenuates the ischaemia-reperfusion response in a chronic postichaemia pain model, Oxid Med Cell Longev. 2015, 2015: 380403.
Sun L.T., TAI W.L., QIU Q., LUO X., MITCHELL R., FLEETWOOD-WALKER S. and Cheung C.W., Role Of Endocannabinoids In Epidural Spinal Cord Stimulation-induced Analgesia In Rats. , The Combined Scientific Meeting Of The Oriental Congress Of Anesthesiology And Perioperative Medicine (ocap 2015) & International Federation Of Societies Of Intravenous Anaesthesia (ifiva 2015). 2015.
TAI W.L., Sun L.T., PAN Z., QIU Q. and Cheung C.W., Inhibition Of Spinal Endothelin Type A Receptor Ameliorates Neuropathic Pain Through Down-regulation Of Mapk And Nf--κb P65 In Rats, 2015.


Researcher : Rodrigo MRC

Project Title:4th South Asian Confederation of Anaesthesiologists Congress Anaesthesia for Orthognathic Surgery
Investigator(s):Rodrigo MRC
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/1999


Project Title:The Association of Dental Anaesthetists 25th Anniversary Summer Scientific Meeting Patient Controlled Sedation with Propolfol
Investigator(s):Rodrigo MRC
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2002




Researcher : Sun LT

List of Research Outputs

LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central Cxcl12/cxcr4 Axis Contributes To The Pain Induction In A Mouse Model Of Complex Regional Pain Syndrome-type I, International Anesthesia Research Society 2015 Annual Meeting And International Science Symposium. 2015.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central administration of C-x-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice, PLoS One. 2014, 9(8): e104860.
Sun L.T., TAI W.L., QIU Q., LUO X., MITCHELL R., FLEETWOOD-WALKER S. and Cheung C.W., Role Of Endocannabinoids In Epidural Spinal Cord Stimulation-induced Analgesia In Rats. , The Combined Scientific Meeting Of The Oriental Congress Of Anesthesiology And Perioperative Medicine (ocap 2015) & International Federation Of Societies Of Intravenous Anaesthesia (ifiva 2015). 2015.
Sun L.T., “恩华杯”两岸四地青年麻醉医师论文大赛优秀奖, 上海市医学会, 2015.
TAI W.L., Sun L.T., PAN Z., QIU Q. and Cheung C.W., Inhibition Of Spinal Endothelin Type A Receptor Ameliorates Neuropathic Pain Through Down-regulation Of Mapk And Nf--κb P65 In Rats, 2015.


Researcher : TAI WL

List of Research Outputs

Cheung C.W., LUO X., TAI W.L., Hung K.L., Chung S.K. and Xiao M.W., Targeted over-expression of astrocytic endothelin-1 attenuates neuropathic pain by up-regulating spinal excitatory amino acid transporter-2, In: Victor KL Hung, Lydia W Tai1, Xin Luo, Xiao Min Wang, Sookja K Chung and Chi Wai Cheung, Journal of Molecular Neuroscience. 2015, 2015 (In Press).
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central Cxcl12/cxcr4 Axis Contributes To The Pain Induction In A Mouse Model Of Complex Regional Pain Syndrome-type I, International Anesthesia Research Society 2015 Annual Meeting And International Science Symposium. 2015.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central administration of C-x-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice, PLoS One. 2014, 9(8): e104860.
Liman S., Cheung C.W., Wong K., TAI W.L., QIU Q., Ng J.K.F., Choi S.W. and Irwin M.G., Preventive Treatment with Ketamine attenuates the ischaemia-reperfusion response in a chronic postichaemia pain model, Oxid Med Cell Longev. 2015, 2015: 380403.
Sun L.T., TAI W.L., QIU Q., LUO X., MITCHELL R., FLEETWOOD-WALKER S. and Cheung C.W., Role Of Endocannabinoids In Epidural Spinal Cord Stimulation-induced Analgesia In Rats. , The Combined Scientific Meeting Of The Oriental Congress Of Anesthesiology And Perioperative Medicine (ocap 2015) & International Federation Of Societies Of Intravenous Anaesthesia (ifiva 2015). 2015.
TAI W.L., Sun L.T., PAN Z., QIU Q. and Cheung C.W., Inhibition Of Spinal Endothelin Type A Receptor Ameliorates Neuropathic Pain Through Down-regulation Of Mapk And Nf--κb P65 In Rats, 2015.


Researcher : Vanhoutte PMGR

Project Title:Annual Summer School in Danish Cardiovascular Research Academy Veins in health and disease
Investigator(s):Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2007


Project Title:Visiting Research Professors Scheme 2009-10
Investigator(s):Vanhoutte PMGR
Department:Pharmacology & Pharmacy
Source(s) of Funding:Visiting Research Professors Scheme
Start Date:09/2009


Project Title:A Study of the Relative Significance of Nitric Oxide Synthase vs NADPH oxidase in Endothelial Senescence
Investigator(s):Vanhoutte PMGR, Wang Y
Department:Pharmacology & Pharmacy
Source(s) of Funding:Small Project Funding
Start Date:10/2009


List of Research Outputs

Gu P., Hui X., Vanhoutte P.M.G.R., Lam K.S.L. and Xu A., Deletion of SIRT1 in perivascular adipose tissue accelerates obesity-induced endothelial dysfunction , ASCEPT-BPS2015.


Researcher : Wang T

List of Research Outputs

Sun W., Wang Z.P., Gui P., Xia W., Xia Z., Zhang X.C., Deng Q.Z., Xuan W., Marie C., Wang L.L., Wu Q.P., Wang T. and Lin Y., Endogenous expression pattern of resolvin D1 in a rat model of self-resolution of lipopolysaccharide-induced acute respiratory distress syndrome and inflammation, International Immunopharmacology. 2014, 23: 247-253.


Researcher : Wong GTC

Project Title:The cardiac preconditioning effect of surgery patients
Investigator(s):Wong GTC, Irwin MG, Hiong YT, Das SR
Department:Anaesthesiology
Source(s) of Funding:Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme
Start Date:10/2007


Project Title:Evaluation of the association between the stress and inflammatory response with cognitive function after surgery in aged mice
Investigator(s):Wong GTC, Chang RCC
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:01/2014


Project Title:The impact of preoperative and postoperative haemoglobin level on rehabilitation duration in fracture hip patients
Investigator(s):Wong GTC, Leung FKL
Department:Anaesthesiology
Source(s) of Funding:AOTrauma
Start Date:09/2014


Project Title:The evaluation of insulin resistance as a precipitating factor for postoperative cognitive dysfunction
Investigator(s):Wong GTC, Chang RCC
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:05/2015


List of Research Outputs

Chu M.T., Lau C.F., Chang R.C.C. and Wong G.T.C., Exploring the potential impact of endurance exercise in Alzheimer’s disease, International Alzheimer’s Disease Conference 2015.
HUANG C., Ng T.W., Chu M.T., Chang R.C.C. and Wong G.T.C., Correlation between tau hyperphosphorylation and inflammation in post operative cognitive dysfunction, International Alzheimer’s Disease Conference 2015.
HUANG C., Ho Y.S., Ng T.W., Irwin M.G., Chang R.C.C. and Wong G.T.C., Dexmedetomidine directly increases tau phosphorylation, Journal of Alzheimer's Disease. 2015, 44: 839-850.
Irwin M.G., Cheung C.W. and Wong G.T.C., Conscious sedation for surgical procedures, In: MG Irwin and GTC Wong, Dexmedetomidine: handbook of clinical applications (second edition). 2015.
Irwin M.G. and Wong G.T.C., Myocardial protection during cardiac surgery, In: R Peter Alston, Paul S. Myles and Marco Ranucci, Oxford Textbook of Cardiothoracic Anaesthesia. 2015.
Irwin M.G. and Wong G.T.C., Remifentanil and Opioid-Induced Cardioprotection, Journal of Cardiothoracic and Vascular Anesthesia. 2015, 29: S23-S26.
LEUNG W.Y.Y., Ng T.W., Chu M.T., Chang R.C.C. and Wong G.T.C., Investigating the modulatory effects of sevoflurane on systemic inflammation-induced cognitive dysfunction, International Alzheimer’s Disease Conference 2015.
Liu Y., Jin J., Qiao S., Lei S., Liao S., Ge Z.D., Li H., Wong G.T.C., Irwin M.G. and Xia Z., Inhibition of PKCb2 overexpression ameliorates myocardial ischaemia/reperfusion injury in diabetic rats via restoring caveolin-3/Akt signaling, Clin Sci (Lond). 2015, 129(4): 331-344.
Ng T.W., HUANG C., Lau C.F., Wong G.T.C. and Chang R.C.C., The potential impact of anaesthesia induced synaptic proteins changes on post-operative cognitive dysfunction (POCD), International Alzheimer’s Disease Conference 2015.
Wong G.T.C., Airway Management in the ICU, Covidien's Asia 1st advance course in respiratory care. 2015.
Wong G.T.C., Associate Editor, Journal of Alzheimer's Disease. 2015.
Wong G.T.C., BIS, Entropy, Spectral Array: putting awareness monitoring in perspective, Fortis Memorial Research Institute Continual Education Program. 2014.
Wong G.T.C., Cognitive dysfunction in the elderly post anesthesia: prevalence, financial and social impact, 4th Asia Anaesthesia Forum Scientific Meeting / 91st Annual Scientific Meeting of the Korean Society of Anesthesiologist. 2014.
Wong G.T.C., Jenkins C.R., Tsang J.W.H., Chen J.Y., Chan L.C. and Tanner J.A., Finalist for Best Free Communication , Asia Pacific Medical Education Conference. 2015.
Wong G.T.C., Internal Examiner for PhD Thesis titled "In vivo exposure to lipopolysaccharide unmasks contractions to the alpha2-adrenergic agonist dexmedetomidine in the rat aorta", 2014.
Wong G.T.C., Internal Examiner for PhD Thesis titled "Patient Outcome and Brain State Monitoring During General Anesthesia", 2015.
Wong G.T.C., Post-surgical Performance in Alzheimer’s Disease Patients, International Alzheimer’s Disease Conference 2015. 2015.
Wong G.T.C., Reviewer for Manuscript Paper ID 1920333 Open Journal of Anesthesiology, 2015.
Wong G.T.C., Reviewer for manuscript Paper ID: 1920356, Open Journal of Anesthesiology. 2015.
Wong G.T.C., Reviewer for manuscript number 1920312 of the Open Journal of Anesthesiology, 2014.
Wong G.T.C., Reviewer for manuscript number 4385, Hong Kong Medical Journal, 2014.
Wong G.T.C., Reviewer for manuscript number 4563 Hong Kong Medical Journal, 2015.
Wong G.T.C., Reviewer for manuscript number ACRGROUP-14-644 Journal of Addiction Research & Therapy, 2014.
Wong G.T.C., Reviewer for manuscript number JNIP-D-14-00095 of the Journal of Neuroimmune Pharmacology, 2014.
Wong G.T.C., Reviewer for manuscript number LFS-D-15-00217 Life Sciences, 2015.
Wong G.T.C., Reviewer for manuscript number NSC-14-1694 Neuroscience, 2014.
Wong G.T.C., Jenkins C.R., Tsang J.W.H., Chen J.Y., Chan L.C. and Tanner J.A., Use of film to build student empathy and enable reflective thought in a new Medical Humanities programme embedded within the undergraduate MBBS curriculum., 12th Asia Pacific Medical Education Conference, Singapore (awarded Finalist prize in the Free Communication Session) (2015). 2015.
Wong G.T.C., Jenkins C.R., Tsang J.W.H., Chen J.Y., Chan L.C. and Tanner J.A., Use of film to build student empathy and enable reflective thought, Asia Pacific Medical Education Conference. 2015.
Xu J., LI H., Irwin M.G., Xia Z.Y., MAO X., Lei S., Wong G.T.C., Hung V., Cheung C.W., Fang X., Clanachan A.S. and Xia Z., Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Crit Care Med. 2014, 42(8): e583-94.


Researcher : Wong K

List of Research Outputs

Liman S., Cheung C.W., Wong K., TAI W.L., QIU Q., Ng J.K.F., Choi S.W. and Irwin M.G., Preventive Treatment with Ketamine attenuates the ischaemia-reperfusion response in a chronic postichaemia pain model, Oxid Med Cell Longev. 2015, 2015: 380403.
Wong K., Wu Y.R., Cheng K.S., Chan P., Cheung C.W., Lu D.Y., Su T.H., Liu Z.M. and King Y.M., Palmitic acid-induced lipotoxicity and protection by (+)- catechin in rat cortical astrocytes, Pharmacological reports 2014. In press. 2014.
Wong K., Cheung C.W., Chao C.Z., SO E.C., Huang B.M. and Leung Y.M., The molecular mechanism of the anti-oxidative effects of tannic acid on palmitic acid-induced cytotoxicity in pneumocytes., 19th World Congress on Heart Disease, Boston, July 25-28 2014.


Researcher : Wong SCS

Project Title:Spinal neuron plasticity following propofol treatment in vitro
Investigator(s):Wong SCS, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:01/2014


Project Title:Intrathecal administration of RhoA, ROCK and ERK inhibitors reduces thermal and inflammatory hyperalgesia in DLC2-/- (knockout) mice
Investigator(s):Wong SCS, Chung SK, Cheung CW
Department:Anaesthesiology
Source(s) of Funding:Small Project Funding
Start Date:04/2015




Researcher : Xia Z

Project Title:Nitrate tolerance compromises propofol protection of the endothelium against inflammation: The role of PKC-beta2 and NADPH oxidase interaction
Investigator(s):Xia Z
Department:Anaesthesiology
Source(s) of Funding:SCA Research Starter and MidCareer Grants
Start Date:07/2008


Project Title:Effects of Adiponectin on Diabetic Heart Sensitivity to Ischemic Postconditioning: Role of STAT-3 activation
Investigator(s):Xia Z, Irwin MG, Ng JKF, Vanhoutte PMGR, Wang Y, Xu A
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2011
Completion Date:09/2014


Project Title:PKC-β2 through downregulating Caveolin-3 increases diabetic heart vulnerability to ischemia-reperfusion injury
Investigator(s):Xia Z, Irwin MG, Vanhoutte PMGR
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:06/2014


Project Title:The role of FoxO1 in diabetic heart susceptibility to ischemia/reperfusion injury and sensitivity to ischemic postconditioning and its interplay with adiponectin
Investigator(s):Xia Z, Vanhoutte PMGR, Xu A, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2014


Project Title:Role of Brg1 in Sevoflurane Postconditioning Cardioprotection in Normal and Diabetic rodents and its interplay with STAT3
Investigator(s):Xia Z, Irwin MG, Wong GTC, Xu A, Wang JJ
Department:Anaesthesiology
Source(s) of Funding:Seed Funding Programme for Basic Research
Start Date:03/2015


Project Title:Experimental Biology 2015; Dexmedetomidine enhances cerebral cortex GIRK1 protein expression and attenuates Acute Postoperative Pain in rats.
Investigator(s):Xia Z
Department:Anaesthesiology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2015


List of Research Outputs

Jiang Y., Zhou Z., Meng Q.T., Sun Q., Su W., Lei S., Xia Z. and Xia Z.Y., Ginsenoside Rb1 Treatment Attenuates Pulmonary Inflammatory Cytokine Release and Tissue Injury following Intestinal Ischemia Reperfusion Injury in Mice, Oxidative Medicine and Cellular Longevity. 2015, 2015: 1-12.
LI H., Irwin M.G. and Xia Z., AHA International travel award, American Heart Association (AHA). 2014.
LI H., Irwin M.G. and Xia Z., Caveolin-3/AdipoR1 dependent mitochondrial STAT3 activation in ischemic postconditioning cardioprotection, Experimental Biology 2015. FASEB, 2015, 29(1):777.3: 777.3.
LI H., Irwin M.G. and Xia Z., Graduate Student Scientist Award, American Society of Pharmacology and Experimental Therapeutics (ASPET). 2015.
LI H., Irwin M.G. and Xia Z., Ischemic postconditioning confers cardioprotection through adiponectin-dependent mitochondrial STAT3 activation in mice, American Heart Association Scientific Sessions, Chicago, USA, 15-19 Nov, 2014.. 2014, Circulation, 2014, 130: A13879.
LI H., Yao W., Irwin M.G. and Xia Z., Propofol postconditioning confers hepatic protection via activating nrf2 in the early minutes of reperfusion which requires adiponectin in mice., IARS Annunal Meeting 2015. Anesth Analg 2015; 120;: S-154.
LI H., Tian Y., Liu P., Xu J.M., Irwin M.G., Tian G.G. and Xia Z., captopril pre-treatment produces additive cardioprotective effects to isoflurane preconditioning in attenuating myocardial ischemia reperfusion injury in rabbits and in humans, IARS Annunal Meeting. 2015, Anesth Analg 2015; 120.: S-34.
LIU Y., JIN J., LI H., Huang H., Irwin M.G. and Xia Z., nhibition of PKCβ2 Attenuates Myocardial Ischemia Reperfusion Injury in Diabetic Rat Through Cavolin-3-dependant Akt Activation, American Heart Association Annunal meeting. 2014, Circulation. 2014:130: A18247.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central Cxcl12/cxcr4 Axis Contributes To The Pain Induction In A Mouse Model Of Complex Regional Pain Syndrome-type I, International Anesthesia Research Society 2015 Annual Meeting And International Science Symposium. 2015.
LUO X., TAI W.L., Sun L.T., QIU Q., Xia Z., Chung S.K. and Cheung C.W., Central administration of C-x-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice, PLoS One. 2014, 9(8): e104860.
Li H., Yao W., Irwin M.G., Wang T., Wang S., Zhang T. and Xia Z., Adiponectin ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction by concomitantly activating Nrf2 and Brg1, Free Radic Biol Med. 2015, 84: 311-321.
Li M.J., Liu Z., Wang P., Wong M.P., Yeager M., Sham P.C., Chanock S.J., Xia Z. and Wang J.J., A Comprehensive Database for GWAS ¬identified Human Genetic Variants: An Update of GWASdb, The 2015 American College of Medical Genetics and Genomics (ACMG) Annual Clinical Genetics Meeting, Salt Lake City, US, 24-28 Mar 2015.. 2015.
Li T., Li J., LI H., Xia Z., Shi X., Li X. and Liu Y., [Effects of hypertonic sodium chloride hydroxyethyl starch solution on cerebral vasospasm following subarachnoid hemorrhage and its mechanism]., Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2014, 26(8): 589-93.
Liu B., Huang W.H., Xiao X., Yu Y., Ma S. and Xia Z., Neuroprotective Effect of Ulinastatin on Spinal Cord Ischemia-Reperfusion Injury in Rabbits, Oxidative Medicine and Cellular Longevity. 2015, 2015: 1-8.
Liu Y., Jin J., Qiao S., Lei S., Liao S., Ge Z.D., Li H., Wong G.T.C., Irwin M.G. and Xia Z., Inhibition of PKCb2 overexpression ameliorates myocardial ischaemia/reperfusion injury in diabetic rats via restoring caveolin-3/Akt signaling, Clin Sci (Lond). 2015, 129(4): 331-344.
Luo C., Yuan D., Li X., Yao W., Luo G., Chi X., LI H., Irwin M.G., Xia Z. and Hei Z., Propofol attenuated acute kidney injury after orthotopic liver transplantation via inhibiting gap junction composed of connexion 32, Anesthesiology. 2015, 122(1): 72-86.
Sun W., Wang Z.P., Gui P., Xia W., Xia Z., Zhang X.C., Deng Q.Z., Xuan W., Marie C., Wang L.L., Wu Q.P., Wang T. and Lin Y., Endogenous expression pattern of resolvin D1 in a rat model of self-resolution of lipopolysaccharide-induced acute respiratory distress syndrome and inflammation, International Immunopharmacology. 2014, 23: 247-253.
WANG Y., WANG P., Xia Z., Lian Q., Zhang M.Q. and Wang J.J., EATdb: A Database of Human Enhancers and Their Putative Targets, 19th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, December 10 & 11, 2014.. 2014.
Wang L., Wu Z.Q., Liu S.M., LI H., Xia Z. and Huang H., Dexmedetomidine enhances cerebral cortex GIRK1 protein expression and attenuates Acute Postoperative Pain in rats, Experimental Biology 2015. FASEB J. 29:LB503: LB503.
Wang P., Wang L.Y., Lian Q., Zhang M.Q., Xia Z. and Wang J.J., EATdb: a database of human enhancers and their putative targets, The 2015 American College of Medical Genetics and Genomics (ACMG) Annual Clinical Genetics Meeting, Salt Lake City, US, 24-28 March 2015.. 2015.
Wen S.H., Ling Y.H., Liu W.F., Qiu Y.X., Li Y.S., Wu Y., Shen J.T., Xia Z. and Liu K.X., Role of 15-F2t-isoprostane in intestinal injury induced by intestinal ischemia/reperfusion in rats, Free Radic Res. 2014, 48(8): 907-18.
Xia Z., 2015 China Integrated Western and Chinese Anesthesiology Annual meeting, Oxidative stress-mediated myocardial ischemia reperfusion injury and its preoperative intervention. 2015.
Xia Z., 2015 Congress of Chinese Association of Anesthesiologists, Role of Oxidative stress in myocardial ischemia reperfusion injury and its prevention. 2015.
Xia Z., Academic editor, Mediators of Inflammation. 2014, 2014.
Xia Z., Anesthetic protection of the diabetic heart from ischemia reperfusion injury in patients. , Guangdong Provincial Anesthesiologists Society 2014 Annual Meeting (Invited Speaker, and Organising Committe Co-Chair). 2014.
Xia Z., Editor, edited 20 papers for Oxidative Med Cellular Longevity as lead guest editor, Oxidative Med Cellular Longevity. 2015.
Xia Z., Editorial Board Member, Journal of Geriatric Cardiology. 2015.
Xia Z., Executive Editor, Journal of diabetes and metabolism. 2015.
Xia Z., Grant reviewer for NSFC (19 grants reviewed in 2015), NSFC (National Natural Science Foundation of China). 2015.
Xia Z., Guangdong Provincial Hospital Association Anesthesia Management Academic Meeting and Guangzhou International Conference 2014, Medical Scientific Research and NSFC Grant application from a Clinician's Perspective. 2014.
Xia Z., Harvard Medical School/MGH Symposium, Ischemic and anesthetic pre- and post-conditioning: the challenge of protecting the diabetic heart. 2015.
Xia Z., Mediators of Inflammation Guest editor for a Special issue, Mediators of Inflammation. 2015.
Xia Z., Peer Reviewer,, Reviewed 1 research article for "Oxidative Medicine & Ceullar Longevity" .. 2014.
Xia Z., Peer reviewer for Oxidative Medicine & Cellular Longevity (4 papers reviewed), Oxidative Medicine & Cellular Longevity. 2015.
Xia Z., Peer reviewer for PLOS ONE (3 papers reviewed), PLOS ONE. 2015.
Xia Z., Peer reviewer for academic journal, The Lancet (MS# THELANCET-D-14-08887). 2015.
Xia Z., Peer reviewer for journal (Anesthesiology), Anesthesiology. 2015.
Xia Z., Peer reviewer for journal (Anesthesiology), Anesthesiology. 2015.
Xia Z., Peer reviewer for journal (Can J Anesth, reviewed 1 paper), Can J. Anesthesia. 2015.
Xia Z., Peer reviewer for journal (Diabetes, MS# DB15-0311), Diabetes. 2015.
Xia Z., Peer reviewer for journal (Diabetes, MS#DB15-0590), Diabetes. 2015.
Xia Z., Peer reviewer for journal (J Diabetes Research, reviewed 1 paper), J Diabetes Research. 2014.
Xia Z., Peer reviewer for journal (Molecular and Cellular Biochemistry, reviewed 1 paper), Molecular and Cellular Biochemistry. 2014.
Xia Z., Peer reviewer for journal (Scientific Reports), 1 paper reviewed, Scientific Reports. 2015.
Xia Z., Peer reviewer, Reviewed 3 manuscripts for Diabetes from Oct 2013 to August 2014, Diabetes. 2014.
Xia Z., Peer reviewer, , Reviewed 4 research articles for "PLoS One" between OCt 2013 to July 2014. 2014.
Xia Z., Peer reviewer: reviewed 3 manuscripts for Diabetes, reviewed 3 manuscripts for Diabetes, from Oct 2013 to Aug 2014. 2014.
Xia Z., Speech Title: Anesthetic Protection of Myocardial Ischemia-reperfusion Injury in Diabetes, Chinese Society of Anesthesiologist (CSA) . 2014.
Xia Z., The effects and disadvantage of antioxidant intervention for organ ischemia injury, Zhejiang Provincial Key Lab of Anesthesiology Research symposium. 2015.
Xia Z., Western China Anesthesiologist Annual Meeting 2015 at Enshi, Anesthetic preconditioning cardioprotection in normal and diabetic subjects. 2015.
Xia Z., Zunyi Medical University Anesthesiology Symposium, Medical Research from research design to SCI publication. 2015.
Xia Z., reviewer and Executive Editor,, Review and edited 5 research articles for "J Diabetes & Metabolism", between Oct 2013 to Aug 2014. 2014.
Xu J., LI H., Irwin M.G., Xia Z.Y., MAO X., Lei S., Wong G.T.C., Hung V., Cheung C.W., Fang X., Clanachan A.S. and Xia Z., Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Crit Care Med. 2014, 42(8): e583-94.


Researcher : Xu J

List of Research Outputs

Xu J., LI H., Irwin M.G., Xia Z.Y., MAO X., Lei S., Wong G.T.C., Hung V., Cheung C.W., Fang X., Clanachan A.S. and Xia Z., Propofol Ameliorates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction via Heme Oxygenase-1/Signal Transducer and Activator of Transcription 3 Signaling Pathway in Rats, Crit Care Med. 2014, 42(8): e583-94.


Researcher : Yao W

List of Research Outputs

LI H., Yao W., Irwin M.G. and Xia Z., Propofol postconditioning confers hepatic protection via activating nrf2 in the early minutes of reperfusion which requires adiponectin in mice., IARS Annunal Meeting 2015. Anesth Analg 2015; 120;: S-154.


Researcher : Yuen VMY

Project Title:Comparison of oral chloral hydrate and intranasal dexmedetomidine for sedation in children undergoing computerised tomography in Queen Mary Hospital
Investigator(s):Yuen VMY, Hui TWC, Wong ICK, Irwin MG
Department:Anaesthesiology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:03/2014




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