DENTAL FACULTY - ORAL BIOSCIENCES
| Researcher : Chan YK |
| Project Title: | Oral Treponemes Phylogenomics: establishing a robust set of genetic markers |
| Investigator(s): | Chan YK, Watt RM, Leung WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2015 |
| List of Research Outputs |
| Chan Y.K., Ma P.Y., Lacap-Bugler D.C., HUO Y., Leung W.K., Leung F.C.C. and Watt R.M., Complete Genome Sequence for Treponema sp. OMZ 838 (ATCC 700772, DSM 16789), Isolated from a Necrotizing Ulcerative Gingivitis Lesion, Genome Announcements. 2014, 2: e01333-14-e01333-14. |
| Lacap-Bugler D.C., Jiang J., HUO Y., Chan Y.K., Leung F.C.C. and Watt R.M., Complete Genome Sequence of the Oral Spirochete Bacterium Treponema putidum Strain OMZ 758T (ATCC 700334T), Genome Announcements. 2014, 2: e01076-14-e01076-14. |
| Researcher : Chau KY |
| List of Research Outputs |
| Chau K.Y., Li N.F., YANG H. and Tsang W.K., Inhibition of Candida albicans hyphal development by sub-lethal levels of solasodine, ASM 2014 - The Australian Society for Microbiology's Annual Scientific Meeting and Exhibition. 2014. |
| Researcher : Epasinghe DJ |
| Project Title: | ISSCR 2015 annual meeting; Immortalization and characterization of mouse dental papilla cells |
| Investigator(s): | Epasinghe DJ |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2015 |
| Researcher : Jung HS |
| Project Title: | Development and regeneration; Implications for total and partial reconstruction of the tooth by dental mesenchymal progenitor cells |
| Investigator(s): | Jung HS |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2013 |
| Project Title: | Harnessing the osteogenic potential of marine biostructures in the development of a new dental "Bioimplant" for seniors (CRF) |
| Investigator(s): | Jung HS |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding for Incubating Group-based Collaborative Research Projects |
| Start Date: | 01/2015 |
| Project Title: | Wound Healing and Dermal Reconstruction to Control the Regenerative Skin |
| Investigator(s): | Jung HS, Green DW |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2015 |
| List of Research Outputs |
| Cha J.Y., Hwang C.J., Kwong S.H., Jung H.S., Kim K.M. and Yu H.S., Strain of bone-implant interface and insertion torque regarding different miniscrew thread designs using an artificial bone model, The European Journal of Orthodontics. 2015, 37: 268-274. |
| Cho E.S., Kim K.J., Lee K.E., Lee E.J., Yun C.Y., Lee M.J., Shin T.J., Hyun H.K., Kim Y.J., Lee S.H., Jung H.S., Lee Z.H. and Kim J.W., Alteration of Conserved Alternative Splicing in AMELX Causes Enamel Defects, Journal of Dental Research. 2015, 93(10): 980-987. |
| Fu-Lai W., Green D.W. and Jung H.S., Linear Poly(ethylenimine) Cross-Linked by Methyl-β-Cyclodextrin for Gene Delivery, Current Gene Therapy. 2014. |
| Green D.W., Goto T. and Jung H.S., Calcifying tissue regeneration via biomimetic materials chemistry, J. R. Soc. Interface. 2014. |
| Green D.W., Kwon H.J. and Jung H.S., Osteogenic Potency of Nacre on Human Mesenchymal Stem Cells, Molecules and Cells. 2015, 38: 267-272. |
| Green D.W., Jung K.M. and Jung H.S., Spontaneous gene transfection of human bone cells using 3D mineralized alginate-chitosan macrocapsules, Journal of Biomedical Materials Research Part A. 2015, n/a-n/a. |
| Ishii A., Muramatsu T., Lee J.M., Higa K., Shinozaki N., Jung H.S. and Shibahara T., Expression of p75NGFR, a Proliferative and Basal Cell Marker, in the Buccal Mucosa Epithelium during Re-epithelialization, The Japan Society of Histochemistry and Cytochemistry. 2014, 47(4): 145-153. |
| Jeong H.S., Lee J.M., Suresh B., Cho K.W., Jung H.S. and Kim K.S., Temporal and Spatial Expression Patterns of miR-302 and miR-367 During Early Embryonic Chick Development, International Journal of Stem Cells. 2014, 7: 162-166. |
| Jin C., Lee J.M., Tang Q., Li L., Lee M.J., Baik H.S. and Jung H.S., Morphological and molecular changes associated with Pitchfork during mouse palate development, Cell Tissue Research. 2014. |
| Jung H.S., Czech Science Foundation, the Czech Republic. 2015. |
| Jung H.S., Editorial Board, Congenital Anomalies Editorial Board. 2015. |
| Jung H.S., Editorial Board, Experimental and Molecular Medicine. 2015. |
| Jung H.S., Editorial Board, Frontiers in Craniofacial Biology. 2015. |
| Jung H.S., Editorial Board, Journal of Oral Biosciences. 2015. |
| Jung H.S., Editorial Board, Regenerative Medicine. 2015. |
| Jung H.S., Immortalization And Characterization Of Mouse Dental Papilla Cells, In: International society for stem cell research, International Society For Stem Cell Research Annual Meetings 2015. |
| Jung H.S., Invited lecture, "A contrasting function for miR-137 in embryonic mammogenesis and adult breast carcinogenesis", Gordon Research Conference - Tissue repair & Regeneration, NH, USA. 2015. |
| Jung H.S., Invited lecture, "Tooth angiogenesis within pulp tissues", Gordon Research Conference - Vascular cell biology, LA, USA. 2015. |
| Jung H.S., Keynote, "Tooth formation by iPS cells", 2015 Kyudai Dental Conference, Fukuoka, Japan. 2015. |
| Jung H.S., Keynotes, "Current opinion in tooth morphogenesis", The 4th Tripartie Conference on Tooth and Bone, Chiba, Japan. 2015. |
| Jung H.S., Poster, "miR-137 in embryonic mammogenesis and adult breast carcinogenesis", Society of Developmental Biology, Seattle, USA. 2014. |
| Jung H.S., Royal Society, International Research Grants, UK. 2015. |
| Kim J.H., Jeon M., Song J.S., Li J.H., Choi B.J., Jung H.S., Moon S.J., DenBesten P.K. and Kim S.O., Distinctive Genetic Activity Pattern of the Human Dental Pulp between Deciduous and Permanent Teeth, PLoS One. 2014, 9(7): 1-7. |
| Kim W.T., Choi H.S., Hwang H.J., Jung H.S., Ryu C.J. and Schnell M.J., Epitope Mapping of Antibodies Suggests the Novel Membrane Topology of B-Cell Receptor Associated Protein 31 on the Cell Surface of Embryonic Stem Cells: The Novel Membrane Topology of BAP31, PLOS ONE. 2015, 10: e0130670. |
| Lai W.F., Oka K. and Jung H.S., Advanced Functional Polymers for Regenerative and Therapeutic Dentistry, Oral Diseases. 2014. |
| Lai W.F., Green D.W. and Jung H.S., Linear poly(ethylenimine) Cross-Linked by Methylb-Cyclodextrain for Gene Delivery, Current Gene Therapy. 2014, 14(4): 258-268. |
| Lee J.M., Cho K.W., Kim E.J., Tang Q., Kim K.S., Tickle C. and Jung H.S., A contrasting function for miR-137 in embryonic mammogenesis and adult breast carcinogenesis, Oncotarget. 2015, 1-10. |
| Lee M.J., Kim E.J., LI L. and Jung H.S., Roles of Wnt inhibitory factor 1 during tooth morphogenesis, Cell and Tissue Research. 2015. |
| Takaichi S., Muramatsu T., Lee J.M., Jung H.S., Shinozaki N., Katakura A. and Yamane G.Y., Re-epithelialization of the Buccal Mucosa after Alkaline Chemical Injury, The Japan Society of Histochemistry and Cytochemistry. 2014, 47(5): 1-7. |
| Researcher : Li NF |
| List of Research Outputs |
| Chau K.Y., Li N.F., YANG H. and Tsang W.K., Inhibition of Candida albicans hyphal development by sub-lethal levels of solasodine, ASM 2014 - The Australian Society for Microbiology's Annual Scientific Meeting and Exhibition. 2014. |
| Researcher : Samaranayake LP |
| Project Title: | 79th General Session and Exhibition of the International Association for Dental Research Turbidometric Evaluation of Polyene-azole Antagonism in C. Albicans |
| Investigator(s): | Samaranayake LP |
| Department: | Dental Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2001 |
| Project Title: | Proteomics of a fluconazole resistant, Candida glabrata strain |
| Investigator(s): | Samaranayake LP, Samaranayake YH |
| Department: | Dental Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2011 |
| Project Title: | Evaluation of biofilm interactions of Candida and gram negative bacteria on the catheter surface |
| Investigator(s): | Samaranayake LP, Samaranayake YH |
| Department: | Dental Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2011 |
| List of Research Outputs |
| Parahitiyawa N., Chu F.C.S., Leung W.K., Yam W.C., Jin L. and Samaranayake L.P., Clonality of bacterial consortia in root canals and subjacent gingival crevices, Journal of Investigative and Clinical Dentistry. 2015, 6(1): 32-39. |
| Taschieri S., Fabbro M.D., Samaranayake L.P. and Chang J.W.W., Microbial Invasion Of Dentinal Tubules: A Literature Review And A New Perspective, Journal of Investigative and Clinical Dentistry. Wiley, 2014, 5: 163 - 170. |
| Researcher : Seneviratne CJ |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Seneviratne CJ |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 12/2011 |
| List of Research Outputs |
| Seneviratne C.J., Fong H.L., Wong S.S.W. and Lee V.H.F., Antifungal susceptibility and phenotypic characterization of oral isolates of a black fungus from a nasopharyngeal carcinoma patient under radiotherapy, BMC oral health. 2015, 15. |
| Tan C.M., Tsoi K.H., Seneviratne C.J. and Matinlinna J.P., Evaluation of the Candida albicans removal and mechanical properties of denture acrylics cleaned by a low-cost powered toothbrush, Journal of Prosthodontic Research. 2014, 58: 243-251. |
| Researcher : Tsang WK |
| Project Title: | Generation of focused libraries by combinatorial biocatalysis with anti-Candidal activity: synthesis and in vitro study |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Mini Grants |
| Start Date: | 01/2009 |
| Project Title: | Investigation of the functional significance of phytase activity in Candida albicans: gene disruption, pH regulation, and virulence study |
| Investigator(s): | Tsang WK, Samaranayake LP |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 03/2012 |
| Project Title: | Perturbation of pH homeostasis: a comparative study on the inhibitory effect of purpurin on membrane-bound ATPases in Candida albicans |
| Investigator(s): | Tsang WK, Samaranayake LP, Lam OLT |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Project Title: | Construction of "arming yeast" for cell surface display of phytase |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 05/2013 |
| Completion Date: | 07/2014 |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Tsang WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 01/2014 |
| List of Research Outputs |
| Chau K.Y., Li N.F., YANG H. and Tsang W.K., Inhibition of Candida albicans hyphal development by sub-lethal levels of solasodine, ASM 2014 - The Australian Society for Microbiology's Annual Scientific Meeting and Exhibition. 2014. |
| Researcher : Watt RM |
| Project Title: | Raising the alarmone in Staphylococcus aureus: establishing the molecular basis of the stringent response |
| Investigator(s): | Watt RM, Seneviratne CJ, Tanner JA |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Research Output Prize (Faculty of Dentistry) |
| Investigator(s): | Watt RM |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Research Output Prize (in Faculty) |
| Start Date: | 01/2013 |
| Project Title: | Molecular analysis of Synergistetes communities associated with chronic and aggressive forms of periodontitis |
| Investigator(s): | Watt RM, Leung WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2013 |
| Project Title: | Whats in your pockets? Single-site analysis of Treponema and Synergistetes populations associated with periodontal health and disease |
| Investigator(s): | Watt RM, Leung WK, Lacap-Bugler DC |
| Department: | Dental Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Project Title: | Breaking the chain or making magic? Establishing the roles of polyphosphate hydrolase proteins in pathogenic bacteria |
| Investigator(s): | Watt RM, Tanner JA, Lacap-Bugler DC |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | Amine production and acid tolerance in oral treponemes: identifying species-specific and conserved pathways |
| Investigator(s): | Watt RM, Leung WK |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2015 |
| Project Title: | IADR/AADR/CADR General Session and exhibition, Boston Massachusetts; Autocatalytic processing of the Tpr thiol protease from Porphyromonas gingivalis |
| Investigator(s): | Watt RM |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 03/2015 |
| Completion Date: | 03/2015 |
| List of Research Outputs |
| ACHARYA A., Koh M.L., Kheur S., Watt R.M., Jin L. and Mattheos N., Salivary IL-1 beta, 'red complex bacteria' and maintenance frequency as predictors of periimplant crevicular fluid IL-1 beta response in periimplant mucositis, Journal of Dental Research. 2015, 94 (Spec Iss A): 3282. |
| Botelho M.G., Lam O.L.T., Watt R.M., Yip V.S.P., Shum D.K.Y. and Lung M.A.K.Y., Peer generated MCQs to assess and support for learning in a Problem Based Learning Programme, International Conference: Assessment for Learning in Higher Education 2015. . |
| Chan Y.K., Ma P.Y., Lacap-Bugler D.C., HUO Y., Leung W.K., Leung F.C.C. and Watt R.M., Complete Genome Sequence for Treponema sp. OMZ 838 (ATCC 700772, DSM 16789), Isolated from a Necrotizing Ulcerative Gingivitis Lesion, Genome Announcements. 2014, 2: e01333-14-e01333-14. |
| KHONG M.L., Li L., Szeto S.C., Watt R.M. and Tanner J.A., Cloning, Expression, Purification and Characterisation of Escherichia coli Polyphosphate Binding Domain as a New Tool to Understanding Polyphosphate Synthesis and Function, 19th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, December 10 & 11, 2014.. 2014. |
| KHONG M.L., Li L., Lu B., Watt R.M. and Tanner J.A., Towards demystifying the implications of polyphosphate-protein binding., Hong Kong Inter-University Postgraduate Symposium on Life Science 2015, Hong Kong. 2015. |
| LU B., Kotaka M. and Watt R.M., Functional characterization of Zymomonas mobilis polyphosphate kinase 2 (PPK2); implications for polyphosphate and nucleotide metabolism, FEBS-EMBO 2014 Conference, Paris, France. 2014. |
| Lacap-Bugler D.C., Jiang J., HUO Y., Chan Y.K., Leung F.C.C. and Watt R.M., Complete Genome Sequence of the Oral Spirochete Bacterium Treponema putidum Strain OMZ 758T (ATCC 700334T), Genome Announcements. 2014, 2: e01076-14-e01076-14. |
| Xiong L., Teng L.L., Watt R.M., Liu C., Lau S.K.P. and Woo P.C.Y., Molecular characterization of arginine deiminase pathway in Laribacter hongkongensis and unique regulation of arginine catabolism and anabolism by multiple environmental stresses, Environmental Microbiology. 2015. |
| ZHUANG L., Watt R.M., Mattheos N., Si M.S., Lai H.C. and Lang N.P., Periodontal and peri-implant microbiota in patients with healthy and inflamed periodontal and peri-implant tissues, Clinical Oral Implants Research. 2014, n/a-n/a. |
| Researcher : Wong SSW |
| Project Title: | Transcriptomic and proteomic view on cellular aging in the model of Candida albicans (OMICS biology perspective) |
| Investigator(s): | Wong SSW, Jin L, Wang Y |
| Department: | Dental Faculty - Oral Biosciences |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2015 |
| List of Research Outputs |
| Herath Mudiyanselage T.D.K.H., Goh B., Sim C., Ong S., Seneviratne C.J., Darveau R.P., Jin L. and Wong S.S.W., Differential response of human monocyte subsets to heterogeneous Pg-LPS Lipid-A structures, Journal of Dental Research. 2015, 94 (Spec Iss A): 4226. |
| LI P., Seneviratne C.J., Wong S.S.W., Vizcaino J.A. and Jin L., Candida biofilm persistence triggered by metabolic inhibition and anti-oxidative response, Journal of Dental Research. 2014, 93 (Spec Iss C): IP_038 (SEA Division). |
| Seneviratne C.J., Fong H.L., Wong S.S.W. and Lee V.H.F., Antifungal susceptibility and phenotypic characterization of oral isolates of a black fungus from a nasopharyngeal carcinoma patient under radiotherapy, BMC oral health. 2015, 15. |