LKS MEDICAL FACULTY
| Researcher : Boheler KR |
| Project Title: | Cell surface glycoprotein to characterize and isolate “homogeneous” human pluripotent stem cell-derived retinal pigmented epithelial cells with enhanced therapeutic potential |
| Investigator(s): | Boheler KR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 09/2014 |
| Project Title: | Mechanistic Study of Vascular Ehlers-Danlos Syndrome using Induced Pluripotent Stem Cells derived from Humans with COL3A1 Mutations |
| Investigator(s): | Boheler KR, Li RA, Chan CWY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2014 |
| Project Title: | Advancing cell-based therapies for Parkinson's through Surfaceome Analyses |
| Investigator(s): | Boheler KR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | SFC / RGC Joint Research Scheme |
| Start Date: | 11/2014 |
| Completion Date: | 10/2015 |
| Project Title: | Establishing an internationally competitive Stem Cell Biotech Cluster in HK: Bioartificial Human Hearts |
| Investigator(s): | Boheler KR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 2) |
| Start Date: | 01/2015 |
| Project Title: | Establishing an Internationally Competitive Stem Cell Biotech Cluster in HK: Bioartificial Human Hearts |
| Investigator(s): | Boheler KR, Li RA |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2015 |
| Project Title: | STF31 and the Selective Ablation of Tumorigenic Human Pluripotent Stem Cells from Differentiated Cells Destined for Regenerative Medicine |
| Investigator(s): | Boheler KR, Lo ACY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| List of Research Outputs |
| Boheler K.R., PHF8 Mediated Histone Demethylation of pmaip Regulates Mesoderm commitment and Cardiomyogenesis of Embryonic Stem Cells, Stem Cells. 2016. |
| HU Q., Wong D.S.H. and Boheler K.R., Utilizing Human Pluripotent Stem Cell-derived RPE cells as therapeutic intervention of AMD, 20th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine of The University of Hong Kong. 2015. |
| Tang Y., Hong Y.Z., Bai H.J., Wu Q., Chen D.G., Lang J.Y., Boheler K.R. and Yang H.T., Plant Homeo Domain Finger Protein 8 Regulates Mesodermal and Cardiac Differentiation of Embryonic Stem Cells Through Mediating the Histone Demethylation of pmaip1 , STEM CELLS. 2016, 34: 1527-1540. |
| Wang Y., Li Z.C., Zhang P.I., Poon N.Y.E., Kong M.C.W., Boheler K.R., Huang Y. and Yao X., Nitric Oxide-cGMP-PKG Pathway Acts on Orai1 to Inhibit the Hypertrophy of Human Embryonic Stem Cell-Derived Cardiomyocytes, STEM CELLS. 2015, n/a-n/a. |
| Researcher : Bruzzone R |
| List of Research Outputs |
| Akhee S.J., Lestra M., Swee L.K., Fan Y., Lamers M.M., Tafesse F.G., Theile C.S., Spooner E., Bruzzone R., Ploegh H.L. and Sanyal S., Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling, Proceedings of the National Academy of Sciences. 2016, 113(6): 705-14. |
| Researcher : Chen Z |
| Project Title: | A novel model for the study of lung pathogenesis of SARS |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | National Institutes of Health, US Department of Health and Human Services - General Award |
| Start Date: | 08/2007 |
| Project Title: | Understanding the Ongoing HIV Epidemic in Yunnan China |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | China AIDS Initiative - General Award |
| Start Date: | 05/2008 |
| Project Title: | Preventing HIV-1 infection using a novel vaccine immunogen |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Global Health Grants |
| Start Date: | 10/2008 |
| Project Title: | Establishment of a rapid, high-throughput, cost-effective HIV-1 drug resistance testing system |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 05/2011 |
| Project Title: | A Novel Vaccine for Mesothelioma Immunotherapy and Prevention; |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Pneumoconiosis Compensation Fund Board - General Award |
| Start Date: | 07/2011 |
| Project Title: | AIDS Vaccine 2011 A Novel Vaccine Design for Inducing Robust HIV-1 Specific Immunity |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2011 |
| Project Title: | Blocking HIV infection by gene-encoding neutralizing antibodies |
| Investigator(s): | Chen Z, Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2012 |
| Project Title: | AIDS Vaccine 2012; Mucosal Prime with a Replicating Vaccinia-based Vaccine Promotes Mucosal Immunity against SIV. |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2012 |
| Project Title: | Mechanism of a soluble PD-1-based vaccine in amplifying antiviral CD8+ T-cell immunity |
| Investigator(s): | Chen Z, Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Completion Date: | 12/2015 |
| Project Title: | Novel Secretory Immunoadhesins for HIV Prevention |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Completion Date: | 06/2016 |
| Project Title: | To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System |
| Investigator(s): | Chen Z, Liu L, Cheung KW, Du DY |
| Department: | Microbiology |
| Source(s) of Funding: | Guangdong-Hong Kong Technology Cooperation Funding Scheme |
| Start Date: | 07/2013 |
| Project Title: | Further optimization of live viral vector for HIV vaccine research |
| Investigator(s): | Chen Z, Wang H |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 11/2013 |
| Completion Date: | 11/2016 |
| Project Title: | To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System |
| Investigator(s): | Chen Z, Liu L, Cheung KW, Du DY |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 12/2013 |
| Project Title: | Mechanism of potentiating HIV antigen-specific CD8+ T cells |
| Investigator(s): | Chen Z, Liu L, Yam WC, Cheung KLA, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2014 |
| Project Title: | A New Therapeutic Vaccine for HIV/AIDS |
| Investigator(s): | Chen Z, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 3) |
| Start Date: | 12/2014 |
| Project Title: | Role of a newly identified PD-1 isoform in modulating immune responses |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | A New Therapeutic Vaccine for HIV/AIDS |
| Investigator(s): | Chen Z, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2015 |
| Project Title: | A novel PDI DNA-based vaccination strategy to mimic Gag-specific responses found in HIV Elite controllers |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | ANR / RGC Joint Research Scheme |
| Start Date: | 04/2015 |
| Project Title: | Role of Δ42PD1 in HIV Infection |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Project Title: | Induction of Mesothelioma-Specific CD8+ T Cell Response for Immunotherapy and Prevention |
| Investigator(s): | Chen Z, Man K |
| Department: | Microbiology |
| Source(s) of Funding: | Pneumoconiosis Compensation Fund Board - General Award |
| Start Date: | 09/2015 |
| Project Title: | Role of PD1-Based Vaccine-Elicited CD8+ T Lymphocytes in Modulating MDSC-associated Immunosuppression |
| Investigator(s): | Chen Z, Cheung KLA, Tan Z |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2016 |
| Researcher : Cheung KLA |
| Project Title: | Human cytomegalovirus and human immunodeficiency virus type 1 co-infection of CD34+ Myeloid Progenitor Cells |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2013 |
| Completion Date: | 08/2016 |
| Project Title: | Transfer of HIV-1 from HIV-1 latently infected CD34+ hematopoietic progenitors to CD4+ T cells |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | Downstream signaling pathways involved in Δ42PD1 cytokine induction |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2015 |
| Completion Date: | 05/2016 |
| Project Title: | Characterising the role of a novel PD1 isoform expressed on gamma-delta T cells in HIV-1 infection |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 06/2016 |
| Researcher : Cheung KW |
| Project Title: | Type of cell death and related mechanisms for gut homing CD4 T cells during human immunodeficiency virus-1 (HIV-1) infection |
| Investigator(s): | Cheung KW, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Completion Date: | 10/2016 |
| Project Title: | Role of microvesicles released by HIV-1 infected gut homing CD4 T cells in AIDS pathogenesis |
| Investigator(s): | Cheung KW, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Completion Date: | 11/2015 |
| Researcher : He M |
| Project Title: | Regulation of ion channels by angiotensin II in human cardiac fibroblasts |
| Investigator(s): | He M, Li GR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2009 |
| Researcher : Hui EC |
| Project Title: | Promotion of the reflection, dialogue and teaching of ethical issues related to the development and uses of biotechnologies among students and faculty members of health-related sciences at the University of Hong Kong |
| Investigator(s): | Hui EC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Teaching Development Grants |
| Start Date: | 03/2005 |
| Researcher : Lai WWK |
| Project Title: | Open label, prospective, double arm, randomized, pilot study to evaluate the safety and efficacy of the same day administration of PDT with verteporfin and an intravitreal injection of ranibizumab vs. ranibizumab monotherapy for the treatment of subfoveal CNV secondary to neovascular age related macular degeneration in the Asian population |
| Investigator(s): | Lai WKW, Li KKW, Wong DSH, McGhee S, Lam CLK, Chan WSC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Pharmaceutical Industry - General Award |
| Start Date: | 07/2008 |
| Project Title: | Production of Iris Pigment Epithelial Cells for transplantation to treat Age-Related Macular Degeneration |
| Investigator(s): | Lai WKW, Lo ACY, Fletcher C, Wong DSH |
| Department: | Ophthalmology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2009 |
| Project Title: | To introduce ranibizumab (Licentis) for the treatment of diabetic macular edema to Queen Mary Hospital and to access the quality of life and utility values before and after the treatment |
| Investigator(s): | Lai WKW, Wong DSH, Li KKW |
| Department: | Ophthalmology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 07/2010 |
| Researcher : Lam PK |
| List of Research Outputs |
| Lam P.K., Yip W.L., Tsui M.S., Ng S.W., Ching C.K. and Mak T.W., Severe rhabdomyolysis and acute kidney injury associated with methoxphenidine, In: Prof. E. Martin Caravati, Clin Toxicol (Phila). 2016, 54: 464-5. |
| Yeung S.H., Lam P.K., Wong T.W. and Chan L.W., Comparison of the GlideScope with the Macintosh laryngoscope in endotracheal intubation during uninterrupted mechanical chest compression: a randomised crossover manikin study, In: Tsui Kwok Leung, Hong Kong Journal of Emergency Medicine. 2016, 23: 159-167. |
| Researcher : Lam SK |
| Project Title: | Biotech Company in the Faculty of Medicine, The University of Hong Kong |
| Investigator(s): | Lam SK |
| Department: | Medicine |
| Source(s) of Funding: | The University of Hong Kong Foundation Seed Grant |
| Start Date: | 07/2003 |
| Project Title: | Treatment of gastrointestinal cancer by targeting survivin using adeno-associated virus gene delivery system |
| Investigator(s): | Lam SK, Wong BCY, Lin MC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2004 |
| Researcher : Leung AYH |
| Project Title: | Provision of free service for serum polyoma BK virus quantification to kidney transplant recipients in Hong Kong |
| Investigator(s): | Leung AYH, Kwong YL, Tang SCW |
| Department: | Medicine |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 01/2009 |
| Project Title: | Detection of WU and KI polyomaviruses from patients with acute respiratory tract infections in Hong Kong |
| Investigator(s): | Leung AYH, Kwong YL |
| Department: | Medicine |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 01/2009 |
| Project Title: | Provision of free molecular tests for patients with acute myeloid leukemia with normal cytogenetics |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 01/2010 |
| Project Title: | Provision of free sorafenib for patients with refractory or relapsed acute myeloid leukemia to bridge them to curative bone marrow transplantation |
| Investigator(s): | Leung AYH, Kwong YL |
| Department: | Medicine |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 07/2010 |
| Project Title: | Study of Microglia and Myeloid Leukemia in Zebrafish |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 05/2013 |
| Project Title: | A novel role of ADP-ribosylation factors-like 4a (arl4a) in definitive hematopoiesis |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2013 |
| Project Title: | Development of Cell Manipulation Tools for Probing Functional Mechanism of Hematopoietic Cells: Robotics, Optical tweezers, and Hematopoiesis |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2014 |
| Project Title: | Provision of free next generation sequencing (NGS) service of prognostic and therapeutic values for patients with acute myeloid leukemia in Hong Kong |
| Investigator(s): | Leung AYH |
| Department: | Medicine |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 03/2016 |
| List of Research Outputs |
| MAN K.F., Leung A.Y.H. and Ma C.H., The Role of Calreticulin (Calr) in Vertebrate Hematopoiesis, The 8th Annual Zebrafish Disease Models Conference. 2015. |
| Ma C.H., Man C.H., HAN H.C. and Leung A.Y.H., A novel role of Aldh16a1 in vertebrate erythropoiesis, The 8th Annual Zebrafish Disease Models ConferenceA novel role of Aldh16a1 in vertebrate erythropoiesis. 2015. |
| Singh G.H.H., Leung A.Y.H., Chan C.C., Lau J.S.M., Chan C., Yip S.F., Liu H., Kho B., Mak V., Lee H.K.K., Lin S.Y., Lau C.K. and Kwong Y.L., Clinicopathologic features and prognostic indicators in Chinese patients with myelofibrosis, Hematology. 2015, 150820070832008. |
| Singh G.H.H., Leung A.Y.H. and Kwong Y.L., Molecularly targeted therapy in acute myeloid leukemia, Future Oncology. 2016. |
| Researcher : Leung GM |
| Project Title: | Evidence-based practice (EBP) learning in the undergraduate medical curriculum - where is the evidence? |
| Investigator(s): | Leung GM, Fielding R, Ho LM, Johnston JM, Lam TH |
| Department: | Community Medicine |
| Source(s) of Funding: | Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants |
| Start Date: | 01/2003 |
| Project Title: | A controlled trial of masks and hand hygiene for reducing influenza transmission |
| Investigator(s): | Leung GM, Cowling BJ, Peiris JSM, Ho LM |
| Department: | Community Medicine |
| Source(s) of Funding: | National Center for Infectious Diseases (NCID) |
| Start Date: | 09/2006 |
| Project Title: | 11th World Congress "Health Economics and Nutrition; Valuing diabetes care in Hong Kong: implications for developing health services in mainland China |
| Investigator(s): | Leung GM |
| Department: | School of Public Health |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2015 |
| Completion Date: | 07/2015 |
| Project Title: | Preventing breast cancer in Hong Kong Chinese women through personalised risk stratification and characterisation: an epidemiologic modelling study and the development of a biorepository of cases and controls |
| Investigator(s): | Leung GM, Kwong A, Wong OL, Lam WWT, Khoo US |
| Department: | School of Public Health |
| Source(s) of Funding: | Commissioned Study on Risk of Breast Cancer in Hong Kong |
| Start Date: | 10/2015 |
| Project Title: | Evaluating the health and health care impact of Hong Kong’s pilot colorectal cancer screening programme |
| Investigator(s): | Leung GM, Law WL, Leung WK |
| Department: | School of Public Health |
| Source(s) of Funding: | Commissioned Study on Evaluation of Government's Colorectal Cancer Screening Pilot Programme |
| Start Date: | 12/2015 |
| List of Research Outputs |
| Cheung D.H., TSANG K.L., Fang J., Xu J., Chan K.H., Ip D.K.M., Peiris J.S.M., Leung G.M. and Cowling B.J., Association of Oseltamivir Treatment With Virus Shedding, Illness, and Household Transmission of Influenza Viruses, Journal of Infectious Diseases. 2015, 212(3): 391-6. |
| Cowling B.J. and Leung G.M., Effectiveness of an internet-delivered handwashing intervention (letter), The Lancet. 2016, 387: 337. |
| Gostin L.O., Tomori O., Wibulpolprasert S., Jha A.K., Frenk J., Moon S., Phumaphi J., Piot P., Stocking B., Dzau V.J. and Leung G.M., Toward a Common Secure Future: Four Global Commissions in the Wake of Ebola, PLOS Medicine. 2016, 13: e1002042. |
| Hui L.L., Leung G.M. and Schooling C.M., Social patterning in adiposity in adolescence: prospective observations from the chinese birth cohort ‘‘Children of 1997’’, PLoS One. 2016, 11: e0146198. |
| Hui L.L., Wong M.Y., Leung G.M. and Schooling C.M., The Association of Infant Growth Patterns with Adiposity in Adolescence: Prospective Observations from Hong Kong's 'Children of 1997' Birth Cohort, Paediatric and Perinatal Epidemiology. 2015, 29(4): 326-34. |
| Ip D.K.M., Lau L.L., Chan K.H., Fang J., Leung G.M., Peiris J.S.M. and Cowling B.J., The dynamic relationship between clinical symptomatology and viral shedding In naturally acquired seasonal and pandemic influenza virus infections, Clinical Infectious Diseases. 2015, 62(4): 431-7. |
| Kwok M.K., Leung G.M. and Schooling C.M., Associations of birth order with early adolescent growth, pubertal onset, blood pressure and size: Evidence from Hong Kong’s “Children of 1997” birth cohort, PLOS ONE. 2016, 11: e0153787. |
| Kwok M.K., Au Yeung S.L.R., Leung G.M. and Schooling C.M., Birth weight and adult cardiovascular risk factors using multiple birth status as an instrumental variable in the 1958 British Birth Cohort, Preventive Medicine. 2016, 84: 69-75. |
| LAI T.C., Au Yeung S.L.R., Lin S.C., Leung G.M. and Schooling C.M., Brief Report: Maternal age of menarche and adiposity: Evidence from Hong Kong's "Children of 1997" birth cohort, Epidemiology. 2016, 27: 433-437. |
| Leung G.M., Hong Kong's Role as an Epidemiologic Sentinel in Global Outbreak Preparedness and Response (Power Point Presentation), International Forum on Quality and Safety in Healthcare, 28-30 September 2015, Hong Kong. 2015. |
| Leung G.M., International Governance: Opportunities for Harmonizing GOF Research Policy and Practice (Discussants), Gain-of-Function Research: The Second Symposium, 10-11 March 2016, Washington DC, USA. 2016. |
| Leung G.M., Primary Health Care and Policy Dimensions, 6th Annual PHFI Research Symposium, 16-18 March 2016, New Delhi. 2016. |
| Leung G.M., The Science and Practice of Public Health Preparedness Against Directly Transmissible Respiratory Pathogens (Power Point Presentation), 1st International Meeting on Respiratory Pathogens, 2-4 September 2015, Singapore. 2015. |
| Leung Y.Y.J., Kwok M.K., Leung G.M. and Schooling C.M., Breastfeeding and childhood hospitalizations for asthma and other wheezing disorders, Annals of Epidemiology. 2016, 26: 21-27.e3. |
| Liao Q., Cowling B.J., Wu P., Leung G.M., Fielding R. and Lam W.W.T., Population Behavior Patterns in Response to the Risk of Influenza A(H7N9) in Hong Kong, December 2013–February 2014, International Journal of Behavioral Medicine. 2015, 22: 672-682. |
| Liao Q., Wu P., Lam W.W.T., Fang J., Wu J.T.K., Leung G.M., Fielding R. and Cowling B.J., Public risk perception and attitudes towards live poultry markets before and after their closure due to influenza A(H7N9), Hong Kong, January–February 2014, Journal of Public Health. 2016, 38: 34-43. |
| Moon S., Sridhar D., Pate M.A., Jha A.K., Clinton C., Delaunay S., Edwin V., Fallah M., Fidler D.P., Garrett L., Goosby E., Gostin L.O., Heymann D.L., Lee K., Leung G.M., Morrison J.S., Saavedra J., Tanner M., Leigh J.A., Hawkins B., Woskie L.R. and Piot P., Will Ebola change the game? Ten essential reforms before the next pandemic. The report of the Harvard-LSHTM Independent Panel on the Global Response to Ebola, The Lancet. 2015, 386: 2204-2221. |
| Ni M.Y., Chan B.H.Y., Leung G.M., Lau E.H.Y. and Pang H.M.H., Transmissibility of the Ice Bucket Challenge among globally influential celebrities: retrospective cohort study, Hong Kong College of Community Medicine Annual Scientific Meeting. 2015. |
| Qin Y., Horby P.W., TSANG K.L., Chen E., Gao L., Ou J., Nguyen T.H., Duong T.N., Gasimov V., Feng L., Wu P., Jiang H., Ren X., Peng Z., Li S., Li M., Zheng J., Liu S., Hu S., Hong R., Farrar J.J., Leung G.M., Gao G.F., Cowling B.J. and Yu H., Differences in the Epidemiology of Human Cases of Avian Influenza A(H7N9) and A(H5N1) Viruses Infection, Clinical Infectious Diseases. 2015, 61(4): 563-71. |
| Schooling C.M. and Leung G.M., Testosterone and cardiovascular risk (Correspondence), The Lancet, Diabetes & Endocrinology. 2015, 3(9): 682. |
| TSANG K.L., Fang J., Perera R.A.P.M., Ip D.K.M., Leung G.M., Peiris J.S.M., Cauchemez S.T. and Cowling B.J., Interpreting Seroepidemiologic Studies of Influenza in a Context of Nonbracketing Sera, Epidemiology. 2016, 27: 152-158. |
| Takahashi S., Liao Q., Van Boeckel T.P., Xing W., Sun J., Hsiao V.Y., Metcalf C.J.E., Chang Z., Liu F., Zhang J., Wu J.T.K., Cowling B.J., Leung G.M., Farrar J.J., Van Doorn H.R., Grenfell B.T. and Yu H., Hand, foot, and mouth disease in China: modeling epidemic dynamics of enterovirus serotypes and implications for vaccination, PLOS Medicine. 2016, 13: e1001958. |
| Tsang K.L., Fang J., Chan K.H., Ip D.K.M., Leung G.M., Peiris J.S.M., Cowling B.J. and Cauchemez S.T., Individual correlates of infectivity of influenza A Virus infections in households, PLoS One. 2016, 11: e0154418. |
| Tsang K.L., Cowling B.J., Fang J., Chan K.H., Ip D.K.M., Leung G.M., Peiris J.S.M. and Cauchemez S.T., Influenza A virus shedding and infectivity in households, Journal of Infectious Diseases. 2015, 212: 1420-1428. |
| Virlogeux V.M.L., Fang J., Wu J.T.K., Ho L.M., Peiris J.S.M., Leung G.M. and Cowling B.J., Brief Report: Incubation Period Duration and Severity of Clinical Disease Following Severe Acute Respiratory Syndrome Coronavirus Infection, Epidemiology. 2015, 26(5): 666-9. |
| WANG H., Lin S.C., Leung G.M. and Schooling C.M., Age at onset of puberty and adolescent depression: "Children of 1997" birth cohort, Pediatrics. 2016, 137: e20153231. |
| WANG H., Leung G.M., Lam H.S. and Schooling C.M., Gestational age and adolescent mental health: evidence from Hong Kong's 'Children of 1997' birth cohort, Archives Of Disease In Childhood. 2015, 100(9): 856-62. |
| Wei L., Chan K.H., Ip D.K.M., Fang J., Fung R.O.P., Leung G.M., Peiris J.S.M. and Cowling B.J., Burden, seasonal pattern, and symptomatology of acute respiratory illnesses of different viral etiology in children presenting at outpatient clinics in Hong Kong. , Clinical Microbiology and Infection . 2015, 21(9): 861-6. |
| Wu J.T.K., Jit M., Zheng Y., Leung S.M., Xing W., Yang J., Liao Q., Cowling B.J., YANG B., Lau E.H.Y., Takahashi S., Farrar J.J., Grenfell B.T., Leung G.M. and Yu H., Correction: Routine pediatric enterovirus 71 vaccination in China: a cost-effectiveness analysis, PLoS Medicine. 2016, 13: e1002013. |
| Wu J.T.K., Jit M., Zheng Y., LEUNG S.M., Xing W., Yang J., Liao Q., Cowling B.J., YANG B., Lau E.H.Y., Takahashi S., Farrar J.J., Grenfell B.T., Leung G.M. and Yu H., Routine pediatric enterovirus 71 vaccination in China: a cost-effectiveness analysis, PLoS Medicine. 2016, 13(3): e1001975. |
| Wu P., Peng Z., Fang J., Feng L., Tsang K.L., Jiang H., Lau E.H.Y., Yang J., Zheng J., Qin Y., Li Z., Leung G.M., Yu H. and Cowling B.J., Human infection with influenza A(H7N9) virus during 3 major epidemic waves, China, 2013–2015, Emerging Infectious Diseases. 2016, 22: 964-972. |
| Wu P., Wang L., Cowling B.J., Yu J., Fang J., Li F., Zeng L., Wu J.T.K., Li Z., Leung G.M. and Yu H., Live Poultry Exposure and Public Response to Influenza A(H7N9) in Urban and Rural China during Two Epidemic Waves in 2013-2014., PLoS One. 2015, 10(9):e0137831. |
| Xu C., Chan K.H., Tsang K.L., Fang J., Fung R.O.P., Ip D.K.M., Cauchemez S.T., Leung G.M., Peiris J.S.M. and Cowling B.J., Comparative epidemiology of influenza B Yamagata- and Victoria-lineage viruses in households, American Journal of Epidemiology. 2015, 182: 705-713. |
| YANG B., Wu P., Wu J.T.K., Lau E.H.Y., Leung G.M., Yu H. and Cowling B.J., Seroprevalence of Enterovirus 71 Antibody Among Children in China: A Systematic Review And Meta-Analysis., Pediatric Infectious Disease Journal. 2015. |
| Yuan J., Lau E.H.Y., Li K., Leung C.Y.H., Yang Z., Xie C., Liu Y., Liu Y., Ma X., Liu J., Li X., Chen K., Luo L., Di B., Cowling B.J., Tang X., Leung G.M., Wang M. and Peiris J.S.M., Effect of Live Poultry Market Closure on Avian Influenza A(H7N9) Virus Activity in Guangzhou, China, 2014, Emerging Infectious Diseases. 2015, 21(10): 1784-93. |
| Researcher : Li G |
| Project Title: | The 10th International Conference on Alzheimer's Disease and Related Disorders High Field MRI Study of the Beta Amyloid and Plaque Desposits in the Brain of APP/PS1 Mice CoQ10 Delays the Brain Atrophy in Transgenic Aged Mice: in Vivo Volume MRI Study |
| Investigator(s): | Li G |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2006 |
| Project Title: | Effect of imbalance of kinases and protein phosphatases on deposit of B amyloid and Tau Pathology in double transgenic APP/PS1 Mice |
| Investigator(s): | Li G, Yang X, Yang ES |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Germany/Hong Kong Joint Research Scheme |
| Start Date: | 01/2007 |
| Researcher : Li RA |
| Project Title: | Cell-based Heart Regeneration |
| Investigator(s): | Li RA, Boheler KR, Chan BP, Chan CWY, Chan GCF, Chien KR, Lee HC, Yue J, Ng RK, Ngan AHW |
| Department: | Medicine |
| Source(s) of Funding: | Theme-based Research Scheme |
| Start Date: | 09/2011 |
| Project Title: | Human WT1 epicardial progenitor cells |
| Investigator(s): | Li RA |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Stem Cell and Regenerative Medicine |
| Investigator(s): | Li RA, Chan GCF, Tse HF |
| Department: | Physiology |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 06/2013 |
| Project Title: | Engineering Calcium Homeostasis of hESC-derived cardiomyocytes |
| Investigator(s): | Li RA |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2013 |
| Project Title: | Ontogenic combinatorial conditioning of 3D human pluripotent stem cell ventricular models for facilitated maturation |
| Investigator(s): | Li RA |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2014 |
| Completion Date: | 12/2015 |
| List of Research Outputs |
| chen G., Karakilkes I., Chow M.Z.Y., Chopra A., Keung W., Chan C.W.Y., Costa K.D., Kong M.C.W., Hajjar R.J., Chen C.S. and Li R.A., Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs., 2015, 8. |
| Researcher : Liu L |
| Project Title: | Early HIV-1 diagnosis using in-house real-time PCR amplification on dried blood spots for men who have sex with men in Hong Kong |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 09/2009 |
| Project Title: | Molecular mechanisms of Nef mediated regulation of PD-1 expression during HIV/SIV infection |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | A novel small molecule from natural product as a potential agent for purging HIV-1 from the latent reservoir |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2014 |
| Project Title: | Defining the role of monocyte-derived dendritic cells in potentiating durable and protective T-cell immunity by a newly identified PD-1 isoform |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | 4th European Congress of Immunology; Spatiotemporal Interplay of Severe Acute Respiratory Syndrome Coronavirus and Respiratory Mucosal Cells Drives Viral Dissemination in Rhesus Macaques |
| Investigator(s): | Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2015 |
| Completion Date: | 09/2015 |
| Project Title: | Mechanisms of viral evasion of vaccine induced T cell immune response |
| Investigator(s): | Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| Researcher : Lok S |
| Project Title: | Generation of ferret (Mustela putorius furo) genomic resources for respiratory infectious disease research: Transcriptomics and comprehensive characterization of cDNAs in a model of influenza infection |
| Investigator(s): | Lok S, Tong AHY, Lee MY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 04/2011 |
| Researcher : Rong J |
| Project Title: | The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy |
| Investigator(s): | Rong J |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2006 |
| Project Title: | Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) for the resolution of neutrophil-induced myocardial injury |
| Investigator(s): | Rong J, Lau ASY, Li XC, Tse HF, Xia Z |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2012 |
| Completion Date: | 09/2015 |
| Project Title: | N-Propargyl caffeamide promotes macrophage transformation from inflammatory M1 to anti-inflammatory M2 phenotypes in the context of myocardial infarction |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 03/2015 |
| Project Title: | Novel caffeic acid derivatives promote the phenotypic and functional switch of macrophages toward resolution of inflammation and cardiac regeneration after myocardial infarction |
| Investigator(s): | Rong J, Li XC |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2015 |
| Project Title: | Characterization of ω-alkynyl arachidonic acid metabolites for the transformation of macrophages from inflammatory M1 to anti-inflammatory M2 phenotype in acute myocardial infarction via suicide inhibition of glycolytic enzyme PKM2 |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2016 |
| Researcher : Sham PC |
| Project Title: | Replication study of susceptibility genes for colorectal cancer |
| Investigator(s): | Sham PC, Ho JWC, Cheng KK |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2007 |
| Project Title: | Partner State Key Laboratory of Brain and Cognitive Sciences |
| Investigator(s): | Sham PC, So KF, Tan L |
| Department: | Centre for Genomic Sciences |
| Source(s) of Funding: | Matching Fund for State Key Laboratory (SKL) |
| Start Date: | 10/2008 |
| Project Title: | Visiting Research Professors Scheme 2009-10 |
| Investigator(s): | Sham PC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Visiting Research Professors Scheme |
| Start Date: | 09/2009 |
| Project Title: | Method and Software for Personal Risk Profiling of Complex Diseases |
| Investigator(s): | Sham PC, Cherny SS, Garcia-Barcelo MM, Kung AWC, Li M, Yang W |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2012 |
| Completion Date: | 12/2015 |
| Project Title: | Bioinformatics tools for identifying disease loci from exome sequencing data |
| Investigator(s): | Sham PC, Cherny SS, Garcia-Barcelo MM, Li M, Yang W |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Genomics |
| Investigator(s): | Sham PC, Chin FYL, Leung FCC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 06/2013 |
| Project Title: | Cross Cultural Differences in Biased Cognition |
| Investigator(s): | Sham PC, Chen EYH, Toulopoulou T |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | ESRC/RGC Joint Research Scheme |
| Start Date: | 09/2013 |
| Project Title: | Statistical methods for characterizing the genetic component of polygenic diseases |
| Investigator(s): | Sham PC, Cherny SS |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Project Title: | Mutational spectrum for dilated cardiomyopathy in Hong Kong |
| Investigator(s): | Sham PC, Tse HF, Cherny SS, Garcia-Barcelo MM, Tang SM, Li M |
| Department: | Centre for Genomic Sciences |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2014 |
| Project Title: | A novel computational framework to identify transcription factor-DNA interaction for cancer genomics |
| Investigator(s): | Sham PC, Yao KM, Wong MP, Wang JJ |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 08/2014 |
| Project Title: | Schizophrenia-related de novo and compound heterozygous mutations |
| Investigator(s): | Sham PC, Chen EYH, Chang WC, Chan KW, Lee HME, Cherny SS, Li M |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2015 |
| Project Title: | Method and software tool for estimating and dissecting the heritability of complex diseases |
| Investigator(s): | Sham PC, Cherny SS, Li M |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2015 |
| List of Research Outputs |
| Cheung C.L., SING C.W., Tang S.M., CHENG K.F., Pirmohamed M., Choi C.H., Hung C.S., Lau E.Y., Lee K.F., Mak M.W., Leung J.Y., Wong T.W., Ho A.Y., Chan K.W., Hung V.H., Tam V., Siu S.C., Sham P.C., Cheung B.M.Y., Wong I.C.K., Tan K.C.B. and Kung A.W.C., HLA-B*38:02:01 Predicts Carbimazole/Methimazole-Induced Agranulocytosis , Clinical Pharmacology & Therapeutics. 2015, 99: 555-61. |
| Dai W., ZHENG H., Cheung A.K.L., Tang S.M., Ko J.M.Y., Wong W.Y., LEONG M.L., Sham P.C., Cheung M.F.F., Kwong D.L.W., Ngan K.C., Ng W.T., Yau C.C., Chiang A.K.S., Lee W.M.A., Lee V.H.F., Lam K.O., Au G.K.H. and Lung M.L., Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma , Proceedings of the National Academy of Sciences. 2016, 113: 3317-3322. |
| Researcher : Wong DSH |
| Project Title: | To introduce bevacizumab for the treatment of macular degeneration and diabetic retinopathy to Queen Mary Hospital |
| Investigator(s): | Wong DSH, Lai WKW, Li KKW |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 03/2008 |
| Project Title: | The Royal College of Ophthalmologists Annual Congress 2009 Can Lutein Protect the Outer Retina? |
| Investigator(s): | Wong DSH |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2009 |
| Researcher : Wong TW |
| List of Research Outputs |
| Yeung S.H., Lam P.K., Wong T.W. and Chan L.W., Comparison of the GlideScope with the Macintosh laryngoscope in endotracheal intubation during uninterrupted mechanical chest compression: a randomised crossover manikin study, In: Tsui Kwok Leung, Hong Kong Journal of Emergency Medicine. 2016, 23: 159-167. |
| Researcher : Wu YH |
| List of Research Outputs |
| Wu Y.H., From Racialization to World Citizenship: The Transnationality of Taiwan and the Early Psychiatric Epidemiological Studies of the World Health Organization, East Asian Science, Technology and Society. Duke University Press, 2016, 10.2. |
| Wu Y.H. and Wang W.J., Making and Mapping Psy Sciences in East and Southeast Asia, East Asian Science, Technology and Society. Duke University Press, 2016, 10.2. |
| Wu Y.H., The Moral Career of ‘Outmates’: Towards a History of Manufactured Mental Disorders in Post-Socialist China, Medical History. Cambridge University Press, 2016, 60: 87-104. |
| Researcher : Yau JMH |
| Project Title: | Angiopoietin-like proteins 3 and 4 as novel inhibitors of lipoprotein lipase: functional and structural studies |
| Investigator(s): | Yau JMH, Xu A, Lam KSL |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2006 |
| Researcher : Zhi H |
| List of Research Outputs |
| Lang H.H.B., Zhi H. and Cowling B.J., Assessing perioperative body weight changes in patients thyroidectomised for a benign non-toxic nodular goitre, Clinical Endocrinology. 2015, Epub on 2015-09-19. |
| Zhi H., Precision care for stroke patients, INFORMS International Conference. 2016. |