DEPT OF PSYCHIATRY



Researcher : Baum LW

List of Research Outputs

Cherny S.S., WONG K.L., Sham P.C., Baum L.W. and Kwan P., Exome sequencing of mesial temporal lobe epilepsy with hippocampal sclerosis in parent-offspring trios, Annual meeting of the Behavior Genetics Association. 2015.
Cherny S.S., Gui H., Kwok M., Sham P.C., Baum L.W. and Kwan P., SNP-based HLA tagging, imputation, and association in adverse drug reaction of epilepsy patients from Hong Kong, 65th Annual Meeting of the American Society of Human Genetics. 2015, 654/W.


Researcher : Campbell DD

Project Title:Effect of Omega-3 Diet on Mouse Transcriptome Following Maternal Immune Activation
Investigator(s):Campbell DD, Li Q, Sham PC
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:04/2015
Completion Date:01/2016




Researcher : Chan CWT

List of Research Outputs

Chang W.C., Waltz J.A., Gold J.M., Chan C.W.T. and Chen E.Y.H., Mild Reinforcement Learning Deficits in Patients With First-Episode Psychosis, Schizophrenia Bulletin. 2016.


Researcher : Chan HC

List of Research Outputs

Bola J., Chan H.C., Chen E.Y.H. and Ng R., Cross-Validating Chinese Language Mental Health Recovery Measures in Hong Kong, Research on Social Work Practice. 2016.


Researcher : Chan HKG

List of Research Outputs

Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.


Researcher : Chan KW

Project Title:Social cognition of people with psychosis-like experiences (PLEs): behavioral and functional imaging study
Investigator(s):Chan KW, Chen EYH, Hui CLM, Wong GHY, Lee HME, Chang WC
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:06/2013


Project Title:"iPEP (Internet-based psychosis education program)": Web-based self-help psychoeducation program for caregivers of patients with psychosis
Investigator(s):Chan KW, Chen EYH, Chang WC, Lee HME, Hui CLM, Wong GHY, Tse SSK
Department:Psychiatry
Source(s) of Funding:Health Care and Promotion Fund - Research Grant Projects
Start Date:09/2013


Project Title:Treatment resistance following the first-episode schizophrenia-spectrum disorder: a retrospective case-control study
Investigator(s):Chan KW, Chen EYH, Chang WC, Lee HME, Wong GHY, Hui CLM, Sham PC
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2014


Project Title:Psychotic-like experience (PLEs) in the general population of Hong Kong: a two-year prospective follow up study
Investigator(s):Chan KW, Chen EYH, Chang WC, Lee HME, Wong GHY, Hui CLM, Chan WC
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2014


Project Title:Genetic polymorphism study on association of inflammatory process and development of treatment-resistant schizophrenia (TRS) in Han-Chinese population
Investigator(s):Chan KW, Chen EYH, Cherny SS, Hui CLM, Lee HME, Chang WC
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:06/2014


Project Title:Exploring the mechanisms of self-referential gaze perception and its potential as an endophenotype in patients with schizophrenia-spectrum disorder
Investigator(s):Chan KW, Chen EYH, Cheung C, Hsiao JHW, Chang WC, Lee HME, Hui CLM
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:International RANZCP Congress of Psychiatry; THE ROLE OF COGNITIVE FUNCTIONING AND SYMPTOMOLOGY IN SELF-STIGMA FORMATION IN PSYCHOSIS/SUBJECTIVE RECOVERY IN PATIENTS WITH FIRST-EPISODE PSYCHOSIS IN HONG KONG
Investigator(s):Chan KW
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2016
Completion Date:05/2016


List of Research Outputs

Chan K.W., 12-year follow-up student of mortality due to suicide among first-episode psychosis cohort: Is the early intervention program more effective in reducing excess mortality due to suicide in psychosis, SIRS 2016 (2-6/4/2016). 2016.
Chan K.W., TAM W.Y.W., LEE K.W., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., A population study of public stigma about psychosis and its contributing factors among Chinese population in Hong Kong, International Journal of Social Psychiatry. 2015, 62(3): 205-213.
Chan K.W., Early Intervention for Psychosis for Asian Populations, 4th Asian Congress of Schizophrenia Research 2015 Taipei (18-20/11/2015). 2015.
Chan K.W., Chau H.S., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong, Early Intervention in Psychiatry. 2016, n/a-n/a.
Chan K.W., Ching Y.N.E., Lam S.C., So H.C., Hui C.L.M., Lee H.M.E., Chang W.C. and Chen E.Y.H., Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis, Early Intervention in Psychiatry. 2015, n/a-n/a.
Chan K.W., Subjective Recovery in Patients with First-Episode Psychosis in Hong Kong, 2016 International RANZCP Congress of Psychiatry (8-12/5/2016). 2016.
Chan K.W., The Role of Cognitive Functioning and Symptomology in Self-Stigma Formation in Psychosis, 2016 International RANZCP Congress of Psychiatry (8-12/5/2016). 2016.
Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impact of avolition and cognitive impairment on functional outcome in first-episode schizophrenia-spectrum disorder: a prospective one-year follow-up study, Schizophrenia Research. 2016, 170: 318-321.
Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.
Chang W.C., Lau F.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E., Lin J. and Chen E.Y.H., Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis, Psychiatry Research. 2016, 242: 144-149.
Chang W.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and risk factors for violent behavior in young people presenting with first-episode psychosis in Hong Kong: A 3-year follow-up study, Australian & New Zealand Journal of Psychiatry. 2015, 49: 914-922.
Chang W.C., Cheung T.Y., Hui C.L.M., Lin J., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and risk factors of depressive symptoms in Chinese patients presenting with first-episode non-affective psychosis in Hong Kong, Schizophrenia Research. 2015.
Chang W.C., Lau S.K., Chiu S.S., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year clinical and functional outcome comparison between first-episode mania with psychotic features and first-episode schizophrenia, Journal of Affective Disorders. 2016, 200: 1-5.
Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].
Chen S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Self-stigma and affiliate stigma in first-episode psychosis patients and their caregivers, Social Psychiatry and Psychiatric Epidemiology. 2016, 1-7.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Lin J., Xu J. and Chen E.Y.H., Delusional disorder and schizophrenia: a comparison of the neurocognitive and clinical characteristics in first-episode patients, Psychological Medicine. 2015.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W. and Chen E.Y.H., Letter to the Editor: Comparing delusional disorder and schizophrenia: a comment on Hui et al. (2015) – a reply, Psychological Medicine. 2016, 46: 1561-1562.
Hui C.L.M., Poon W.Y.V., Kwok S.K.V., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and predictors of medication non-adherence among Chinese patients with first-episode psychosis, Psychiatry Research. 2015, 228 (3): 680-687.
Hui C.L.M., Poon W.Y.V., Ko W.T., Miao H.Y., Chang W.C., Lee H.M.E., Chan K.W., Lin J. and Chen E.Y.H., Risk factors for antipsychotic medication non-adherence behaviors and attitudes in adult-onset psychosis, Schizophrenia Research. 2016.
Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Demographic correlates of medication knowledge in Hong Kong early psychosis patients, Early Intervention in Psychiatry. 2016.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Psychosis patients’ knowledge, adherence and attitudes towards the naming of antipsychotic medication in Hong Kong, Early Interv Psychiatry. 2015, 9 (5): 422-427.
Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.
Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Lin J. and Chen E.Y.H., Letter to the Editor: Comparison of cognitive functions, pre-morbid conditions and clinical characteristics between brief psychotic disorder and schizophrenia, Psychological Medicine. 2016, 46(9): 1-3.
Lee H.M.E., Hui C.L.M., Ching Y.N.E., Lin J., Chang W.C., Chan K.W. and Chen E.Y.H., Public Stigma in China Associated With Schizophrenia, Depression, Attenuated Psychosis Syndrome, and Psychosis-Like Experiences, Psychiatry Services. 2016.
Lee W.Y., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., A systematic review on definitions and assessments of psychotic-like experiences, Early Interv Psychiatry. 2016, 10 (1): 3-16.
Lin J., Chan K.W., Lee H.M.E., Chang W.C., Tse M.A., Su W.W., Sham P.C., Hui C.L.M., Joe G.M., Chan C.L.W., Khong P.L., So K.F., Honer W. and Chen E.Y.H., Aerobic Exercise and Yoga Improve Neuro-Cognitive Function in Women with Early Psychosis: Effects of a Randomized Controlled Trial, NPJ Schizophrenia. 2015.
Tong A.C., Lin J., Cheung V.Y., Lau K.M., Chang W.C., Chan K.W., Hui C.L.M., Lee H.M.E. and Chen E.Y.H., A Low-Intensity Mindfulness-Based Intervention for Mood Symptoms in People with Early Psychosis: Development and Pilot Evaluation, Clin Psychol Psychother. 2015.


Researcher : Chan SI

List of Research Outputs

Chang W.C., Lau F.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E., Lin J. and Chen E.Y.H., Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis, Psychiatry Research. 2016, 242: 144-149.
Chang W.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and risk factors for violent behavior in young people presenting with first-episode psychosis in Hong Kong: A 3-year follow-up study, Australian & New Zealand Journal of Psychiatry. 2015, 49: 914-922.


Researcher : Chan WC

Project Title:A validation study of Cantonese version of Apathy Evaluation Scale in cognitively impaired older Chinese
Investigator(s):Chan WC, Law ACK
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2013


Project Title:A randomised controlled trial of home-based exercise intervention for caregivers of persons with dementia
Investigator(s):Chan WC
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2014


List of Research Outputs

Au A., Yip H.M., Chan W.C., Bai X. and Tsien T., Ageing and mental health: challenges and innovations in Hong Kong, Ageing and Mental Health: Global Perspectives. Nova Science Publishers Inc, 2016, 81-96.
Chan W.C., Efficacy of home-based Tai Chi in alleviating depression among caregivers of persons with dementia, The 9th Pong Ding Yuen International Symposium on Traditional Chinese Medicine. 2015.
Chan W.C., Efficacy of home-based exercise in alleviating depression among caregivers of persons with dementia, 9th International Congress of the Asian Society Against Dementia. 2015.
Chan W.C., Evidence-based interventions for older adults with cognitive impairment, Suwon International Mental Health Symposium. 2016.
Chan W.C., Pressure to adhere to treatment among mental health service users in Hong Kong, 12th World Congress of World Association for Psychosocial Rehabilitation. 2015.
Chan W.C., Prevalence of mental disorders and service utilisation in Hong Kong, Moving Ahead: Early Intervention in Mental Health. 2015.
Chan W.C., Recent advances in management of late-life depression, 11th International Symposium on Healthy Aging. 2016.
Chan W.C., Understanding stigma at different ecological levels, 112th Annual Meeting of the Japanese Society of Psychiatry and Neurology. 2016.
Cheng P.W.C., Chan S.S.M., Mak A.D.P., Chan W.C., Cheng S.T., Shi L., Wang D. and Lam L.C.W., Would transcranial direct current stimulation (tDCS) enhance the effects of working memory training in older adults with mild neurocognitive disorder due to Alzheimer’s disease: study protocol for a randomized controlled trial, Trials. 2015, 16.
Cheng S.T., Fung H.H., Chan W.C. and Lam L.C.W., Short-Term Effects of a Gain-Focused Reappraisal Intervention for Dementia Caregivers: A Double-Blind Cluster-Randomized Controlled Trial, The American Journal of Geriatric Psychiatry. 2016.
Ho R.T.H., Cheung K.K.J., Chan W.C., Cheung K.M. and Lam L.C.W., A 3-arm randomized controlled trial on the effects of dance movement intervention and exercises on elderly with early dementia, BMC Geriatrics. 2015, 15.
Lee A.T.C., Richards M., Chan W.C., Chiu H.F.K., Lee R.S.Y. and Lam L.C.W., Intensity and Types of Physical Exercise in Relation to Dementia Risk Reduction in Community-Living Older Adults, Journal of the American Medical Directors Association. 2015, 16: 899.e1-899.e7.
Lee A.T.C., Richards M., Chan W.C., Chiu H.F.K., Lee R.S.Y. and Lam L.C.W., Poor balance as a noncognitive predictor of incident dementia, Journal of the American Geriatrics Society. 2015, 63(8): 1701-1702.
Yang Y.H., Meguro K., Kim S.Y., Shim Y.S., Yu X., Chen C.L.H., Wang H., Lam L., Senanarong V., Dominguez J., Lu P.Y., Lin Y.T., Hu C.J., Chiu P.Y., Fuh J.L., Wang W.F., Yu B.C., Li T., Wang M.W., Situmeang R.F.V., Jang J.W., Zhang J., Chan W.C., Zhou Y.Y., Lou H., Zhang L., Ye M. and Chen X., Impact of Alzheimer's Disease in Nine Asian Countries, Gerontology. 2016.
Yim L.C.L., Leung H.C.M., Chan W.C., Lam M.H.B. and Lim V.W.M., Prevalence of Mental Illness among Homeless People in Hong Kong, PLOS ONE. 2015, 10: e0140940.


Researcher : Chang WC

Project Title:Reward learning impairment in clinical high-risk individuals, first-episode psychosis patients and their non-psychotic siblings: psychosis prediction and endophenotypic investigation
Investigator(s):Chang WC, Lee HME, Wong GHY, Chan KW, Hui CLM, Chen EYH
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:An fMRI study on disrupted sense of agency in psychosis patients in term of decision making dysfluency
Investigator(s):Chang WC, Chen EYH
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:05/2014
Completion Date:05/2016


Project Title:Pathway to care and three-year outcome comparison of extended early intervention service and standard psychiatric care for adults presenting with first-episode psychosis
Investigator(s):Chang WC, Chan KW, Lee HME, Hui CLM, Chen EYH
Department:Psychiatry
Source(s) of Funding:Commissioned Research on Mental Health Policy and Services
Start Date:11/2014


Project Title:A longitudinal multimodal MRI investigation for clinical and functional outcome prediction in individuals at clinical high-risk for psychosis: a prospective 2-year follow-up study
Investigator(s):Chang WC, Chen EYH, Cheung C, Chan KW, Hui CLM, Lee HME, Sham PC, Geng X
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


List of Research Outputs

CHUI S.L.C., WONG Y.S., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Potential association between the use of oral fluoroquinolones and acute neuropsychiatric disorders in Hong Kong: A self-controlled case series study, The ISPE's 9th Asian Conference on Pharmacoepidemiology, Bangkok, Thailand November 14-16, 2015.
Chan K.W., TAM W.Y.W., LEE K.W., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., A population study of public stigma about psychosis and its contributing factors among Chinese population in Hong Kong, International Journal of Social Psychiatry. 2015, 62(3): 205-213.
Chan K.W., Chau H.S., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong, Early Intervention in Psychiatry. 2016, n/a-n/a.
Chan K.W., Ching Y.N.E., Lam S.C., So H.C., Hui C.L.M., Lee H.M.E., Chang W.C. and Chen E.Y.H., Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis, Early Intervention in Psychiatry. 2015, n/a-n/a.
Chang W.C., Demographic and clinical profiles of young people with at-risk mental state for psychosis in Hong Kong, International Symposium cum Training workshop for Jockey Club Early Psychosis Project (JCEP): Moving Ahead: Early Intervention in Mental Health on Nov 28, 2015.. 2015.
Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impact of avolition and cognitive impairment on functional outcome in first-episode schizophrenia-spectrum disorder: a prospective one-year follow-up study, Schizophrenia Research. 2016, 170: 318-321.
Chang W.C., Waltz J.A., Gold J.M., Chan C.W.T. and Chen E.Y.H., Mild Reinforcement Learning Deficits in Patients With First-Episode Psychosis, Schizophrenia Bulletin. 2016.
Chang W.C., Nature and Nurture in Brain Functions, the Annual Scientific Conference of the Hong Kong Society of Neurosciences. 2016.
Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.
Chang W.C., Lau F.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E., Lin J. and Chen E.Y.H., Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis, Psychiatry Research. 2016, 242: 144-149.
Chang W.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and risk factors for violent behavior in young people presenting with first-episode psychosis in Hong Kong: A 3-year follow-up study, Australian & New Zealand Journal of Psychiatry. 2015, 49: 914-922.
Chang W.C., Cheung T.Y., Hui C.L.M., Lin J., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and risk factors of depressive symptoms in Chinese patients presenting with first-episode non-affective psychosis in Hong Kong, Schizophrenia Research. 2015.
Chang W.C., Reinforcement learning deficits in patients with first-episode schizophrenia-spectrum disorder, Neuroscience Symposium 2016. 2016.
Chang W.C., Lau S.K., Chiu S.S., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year clinical and functional outcome comparison between first-episode mania with psychotic features and first-episode schizophrenia, Journal of Affective Disorders. 2016, 200: 1-5.
Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].
Chen S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Self-stigma and affiliate stigma in first-episode psychosis patients and their caregivers, Social Psychiatry and Psychiatric Epidemiology. 2016, 1-7.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Lin J., Xu J. and Chen E.Y.H., Delusional disorder and schizophrenia: a comparison of the neurocognitive and clinical characteristics in first-episode patients, Psychological Medicine. 2015.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W. and Chen E.Y.H., Letter to the Editor: Comparing delusional disorder and schizophrenia: a comment on Hui et al. (2015) – a reply, Psychological Medicine. 2016, 46: 1561-1562.
Hui C.L.M., Poon W.Y.V., Kwok S.K.V., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and predictors of medication non-adherence among Chinese patients with first-episode psychosis, Psychiatry Research. 2015, 228 (3): 680-687.
Hui C.L.M., Poon W.Y.V., Ko W.T., Miao H.Y., Chang W.C., Lee H.M.E., Chan K.W., Lin J. and Chen E.Y.H., Risk factors for antipsychotic medication non-adherence behaviors and attitudes in adult-onset psychosis, Schizophrenia Research. 2016.
Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Demographic correlates of medication knowledge in Hong Kong early psychosis patients, Early Intervention in Psychiatry. 2016.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Psychosis patients’ knowledge, adherence and attitudes towards the naming of antipsychotic medication in Hong Kong, Early Interv Psychiatry. 2015, 9 (5): 422-427.
Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.
Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Lin J. and Chen E.Y.H., Letter to the Editor: Comparison of cognitive functions, pre-morbid conditions and clinical characteristics between brief psychotic disorder and schizophrenia, Psychological Medicine. 2016, 46(9): 1-3.
Lee H.M.E., Hui C.L.M., Ching Y.N.E., Lin J., Chang W.C., Chan K.W. and Chen E.Y.H., Public Stigma in China Associated With Schizophrenia, Depression, Attenuated Psychosis Syndrome, and Psychosis-Like Experiences, Psychiatry Services. 2016.
Lee W.Y., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., A systematic review on definitions and assessments of psychotic-like experiences, Early Interv Psychiatry. 2016, 10 (1): 3-16.
Lin J., Chan K.W., Lee H.M.E., Chang W.C., Tse M.A., Su W.W., Sham P.C., Hui C.L.M., Joe G.M., Chan C.L.W., Khong P.L., So K.F., Honer W. and Chen E.Y.H., Aerobic Exercise and Yoga Improve Neuro-Cognitive Function in Women with Early Psychosis: Effects of a Randomized Controlled Trial, NPJ Schizophrenia. 2015.
Tong A.C., Lin J., Cheung V.Y., Lau K.M., Chang W.C., Chan K.W., Hui C.L.M., Lee H.M.E. and Chen E.Y.H., A Low-Intensity Mindfulness-Based Intervention for Mood Symptoms in People with Early Psychosis: Development and Pilot Evaluation, Clin Psychol Psychother. 2015.
WONG Y.S., Wong I.C.K., Chui S.L.C., Lee H.M.E., Chang W.C., Chen E.Y.H., Leung W.K. and Chan E.W., Association Between Acute Neuropsychiatric Events and Helicobacter pylori Therapy Containing Clarithromycin , JAMA Internal Medicine. 2016, 176(6): 828-834.
WONG Y.S., CHUI S.L.C., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Neuropsychiatric disorders associated with the use of helicobacterpylori eradication therapy containing-clarithromyclin_self-controlled case series, The ISPE's 9th Asian Conference on Pfharmacoepidemiology, Bangkok, Thailand, November 14-16, 2015.


Researcher : Chau HS

List of Research Outputs

Chan K.W., Chau H.S., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong, Early Intervention in Psychiatry. 2016, n/a-n/a.
Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].


Researcher : Chen EYH

Project Title:10th Biennial Winter Workshop on Schizophrenia N400 and P600 Event-Related Potential Responses to Neutral and Affect-laden Semantic Stimulus in Schizophrenic Patients 2) Predictors of Short-term Functional Outcome Following First Episode Psychosis 3) spontaneous Blink Rate in First-episode Schi Predictors of Short-term Functional Outcome Following First Episode Psychosis Spontaneous Blink Rate in First-episode Schizophrenic Patients: a Prospective Follow-up Study and Temporal Evolution of Extra-pyramidal Side-effects to Conventional Anti-psychotic Medications in First-episode Psychosis
Investigator(s):Chen EYH
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:02/2000


Project Title:The Impacts of Yoga and Exercise on Neuro-cognitive Function and Symptoms in Early Psychosis - A single-blinded randomized controlled clinical trial
Investigator(s):Chen EYH, Chiu CPY, Tse MA, Khong PL, Lee TMC, Chan CLW, So KF
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:03/2011


Project Title:The Impacts of Yoga and Aerobic Exercise on Neuro-cognitive Function and Brain Structure in Early Psychosis - A Randomized Controlled Clinical Trial
Investigator(s):Chen EYH, Chan CLW, Chan KW, Chang WC, Chiu CPY, Honer WG, Khong PL, Lam MLM, Sham PC, So KF, Tse MA
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2012


Project Title:fMRI investigation of verbal Information disclosure/non-disclosure in schizophrenic patients and healthy controls
Investigator(s):Chen EYH, Wong GHY, Hui CLM, Lee HME, Chang WC, Chan KW
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:05/2013


Project Title:Five-year follow-up of a randomized controlled trial of the duration of early intervention for psychosis: 2 years vs. 3 years
Investigator(s):Chen EYH, Hui CLM, Wong GHY, Chang WC, Chan KW, Lee HME
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014
Completion Date:11/2016


Project Title:4th Schizophrenia International Research Society Conference; Yoga exercise for cognitive impairment in psychotic disorders
Investigator(s):Chen EYH
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:04/2014


Project Title:Predicting treatment response in first-episode psychosis
Investigator(s):Chen EYH, Hui CLM, Chang WC, Chan KW, Lee HME
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2014


Project Title:12th World Congress of Biological Psychiatry; Treatment guideline for early phase of schiziophrenia
Investigator(s):Chen EYH
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2015


Project Title:Incorporating both traditional mental health recovery and service-user defined personal recovery measures in an outcomes-driven Hong Kong mental health system
Investigator(s):Chen EYH
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2015


Project Title:Neurodevelopmental eflect of gene-environment interaction among early-onset schizophrenia patients: a combined genetic and neuroimaging approach
Investigator(s):Chen EYH, Lee HME, Chang WC, Chan KW, Hui CLM, Lin JJ
Department:Psychiatry
Source(s) of Funding:NSFC/RGC Joint Research Scheme
Start Date:01/2016


Project Title:An exploration of psychotic symptoms and their vulnerability traits by evaluating large-scale semantic networks in psychotic disorders
Investigator(s):Chen EYH, Chang WC, Lee HME, Hui CLM, Chan KW
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


List of Research Outputs

Bola J., Chan H.C., Chen E.Y.H. and Ng R., Cross-Validating Chinese Language Mental Health Recovery Measures in Hong Kong, Research on Social Work Practice. 2016.
CHUI S.L.C., WONG Y.S., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Potential association between the use of oral fluoroquinolones and acute neuropsychiatric disorders in Hong Kong: A self-controlled case series study, The ISPE's 9th Asian Conference on Pharmacoepidemiology, Bangkok, Thailand November 14-16, 2015.
Chan K.W., TAM W.Y.W., LEE K.W., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., A population study of public stigma about psychosis and its contributing factors among Chinese population in Hong Kong, International Journal of Social Psychiatry. 2015, 62(3): 205-213.
Chan K.W., Chau H.S., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong, Early Intervention in Psychiatry. 2016, n/a-n/a.
Chan K.W., Ching Y.N.E., Lam S.C., So H.C., Hui C.L.M., Lee H.M.E., Chang W.C. and Chen E.Y.H., Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis, Early Intervention in Psychiatry. 2015, n/a-n/a.
Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impact of avolition and cognitive impairment on functional outcome in first-episode schizophrenia-spectrum disorder: a prospective one-year follow-up study, Schizophrenia Research. 2016, 170: 318-321.
Chang W.C., Waltz J.A., Gold J.M., Chan C.W.T. and Chen E.Y.H., Mild Reinforcement Learning Deficits in Patients With First-Episode Psychosis, Schizophrenia Bulletin. 2016.
Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.
Chang W.C., Lau F.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E., Lin J. and Chen E.Y.H., Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis, Psychiatry Research. 2016, 242: 144-149.
Chang W.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and risk factors for violent behavior in young people presenting with first-episode psychosis in Hong Kong: A 3-year follow-up study, Australian & New Zealand Journal of Psychiatry. 2015, 49: 914-922.
Chang W.C., Cheung T.Y., Hui C.L.M., Lin J., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and risk factors of depressive symptoms in Chinese patients presenting with first-episode non-affective psychosis in Hong Kong, Schizophrenia Research. 2015.
Chang W.C., Lau S.K., Chiu S.S., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year clinical and functional outcome comparison between first-episode mania with psychotic features and first-episode schizophrenia, Journal of Affective Disorders. 2016, 200: 1-5.
Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].
Chen E.Y.H., Early Intervention in psychosis in a real life setting, Australasian Schizophrenia Congress, International Congress of Schizophrenia Research Schizophrenia International Research Society.. 2015.
Chen E.Y.H., Efficacy of early intervention for psychosis, International Symposium on Youth Mental Health. 2015.
Chen E.Y.H., Optimizing management of early schizophrenia disorders, Royal Australian and New Zealand College of Psychiatrists International conference. 2016.
Chen E.Y.H., Strategies and Outcomes in real-life early psychosis Intervention, International Symposium for Mental Health, Chonnam National University Medical School, Korea. 2016.
Chen E.Y.H., Tackling Discrimination Towards Psychosis: Concepts and Evidence, Japanese Society of Psychiatry and Neurology International Symposium. 2016.
Chen S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Self-stigma and affiliate stigma in first-episode psychosis patients and their caregivers, Social Psychiatry and Psychiatric Epidemiology. 2016, 1-7.
Csillag C., Nordentoft M., Mizuno M., Jones P.B., Killackey E., Taylor M., Chen E.Y.H., Kane J. and McDaid D., Early intervention services in psychosis: from evidence to wide implementation, Early Intervention in Psychiatry. 2015, n/a-n/a.
De Deyne S., Elvevåg B., Hui C.L.M., Poon W.Y.V. and Chen E.Y.H., Rich semantic networks applied to schizophrenia: A new framework, Schizophrenia Research. 2016.
Ho R.T.H., Chan K.P.C., Lo H.Y.P., Wong P.H., Chan C.L.W., Leung P.P.Y. and Chen E.Y.H., Understandings of spirituality and its role in illness recovery in persons with schizophrenia and mental-health professionals: a qualitative study, Bmc Psychiatry. 2016, 16.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Lin J., Xu J. and Chen E.Y.H., Delusional disorder and schizophrenia: a comparison of the neurocognitive and clinical characteristics in first-episode patients, Psychological Medicine. 2015.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W. and Chen E.Y.H., Letter to the Editor: Comparing delusional disorder and schizophrenia: a comment on Hui et al. (2015) – a reply, Psychological Medicine. 2016, 46: 1561-1562.
Hui C.L.M., Poon W.Y.V., Kwok S.K.V., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and predictors of medication non-adherence among Chinese patients with first-episode psychosis, Psychiatry Research. 2015, 228 (3): 680-687.
Hui C.L.M., Poon W.Y.V., Ko W.T., Miao H.Y., Chang W.C., Lee H.M.E., Chan K.W., Lin J. and Chen E.Y.H., Risk factors for antipsychotic medication non-adherence behaviors and attitudes in adult-onset psychosis, Schizophrenia Research. 2016.
Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Demographic correlates of medication knowledge in Hong Kong early psychosis patients, Early Intervention in Psychiatry. 2016.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Psychosis patients’ knowledge, adherence and attitudes towards the naming of antipsychotic medication in Hong Kong, Early Interv Psychiatry. 2015, 9 (5): 422-427.
Lee H.M.E., So H.C. and Chen E.Y.H., Admission Rates and Psychiatric Beds in Hong Kong, 1999–2014: A Population-Based Study, Psychiatric Services. 2016, 67: 579-579.
Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.
Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Lin J. and Chen E.Y.H., Letter to the Editor: Comparison of cognitive functions, pre-morbid conditions and clinical characteristics between brief psychotic disorder and schizophrenia, Psychological Medicine. 2016, 46(9): 1-3.
Lee H.M.E., Hui C.L.M., Ching Y.N.E., Lin J., Chang W.C., Chan K.W. and Chen E.Y.H., Public Stigma in China Associated With Schizophrenia, Depression, Attenuated Psychosis Syndrome, and Psychosis-Like Experiences, Psychiatry Services. 2016.
Lee W.Y., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., A systematic review on definitions and assessments of psychotic-like experiences, Early Interv Psychiatry. 2016, 10 (1): 3-16.
Lin J., Chan K.W., Lee H.M.E., Chang W.C., Tse M.A., Su W.W., Sham P.C., Hui C.L.M., Joe G.M., Chan C.L.W., Khong P.L., So K.F., Honer W. and Chen E.Y.H., Aerobic Exercise and Yoga Improve Neuro-Cognitive Function in Women with Early Psychosis: Effects of a Randomized Controlled Trial, NPJ Schizophrenia. 2015.
Longenecker J., Hui C.L.M., Chen E.Y.H. and Elvevag B., Concepts of ‘self’ in delusion resolution, Schizophrenia Research: Cognition. 2016, 3: 8-10.
Ran M., WENG X., Chan C.L.W., Chen E.Y.H., Tang C.P., Lin F.R., Mao W.J., Hu S.H., Huang Y.Q. and Xiang M.Z., Different outcomes of never-treated and treated patients with schizophrenia: 14-year follow-up study in rural China, The British Journal of Psychiatry. 2015, 207 (6): 495-500.
Tong A.C., Lin J., Cheung V.Y., Lau K.M., Chang W.C., Chan K.W., Hui C.L.M., Lee H.M.E. and Chen E.Y.H., A Low-Intensity Mindfulness-Based Intervention for Mood Symptoms in People with Early Psychosis: Development and Pilot Evaluation, Clin Psychol Psychother. 2015.
WONG Y.S., Wong I.C.K., Chui S.L.C., Lee H.M.E., Chang W.C., Chen E.Y.H., Leung W.K. and Chan E.W., Association Between Acute Neuropsychiatric Events and Helicobacter pylori Therapy Containing Clarithromycin , JAMA Internal Medicine. 2016, 176(6): 828-834.
WONG Y.S., CHUI S.L.C., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Neuropsychiatric disorders associated with the use of helicobacterpylori eradication therapy containing-clarithromyclin_self-controlled case series, The ISPE's 9th Asian Conference on Pfharmacoepidemiology, Bangkok, Thailand, November 14-16, 2015.


Researcher : Chen SM

List of Research Outputs

Chen S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Self-stigma and affiliate stigma in first-episode psychosis patients and their caregivers, Social Psychiatry and Psychiatric Epidemiology. 2016, 1-7.


Researcher : Cheng PWC

List of Research Outputs

Cheng P.W.C., Chan S.S.M., Mak A.D.P., Chan W.C., Cheng S.T., Shi L., Wang D. and Lam L.C.W., Would transcranial direct current stimulation (tDCS) enhance the effects of working memory training in older adults with mild neurocognitive disorder due to Alzheimer’s disease: study protocol for a randomized controlled trial, Trials. 2015, 16.


Researcher : Cherny SS

Project Title:Variance components models for mapping QTLs
Investigator(s):Cherny SS, Sham PC
Department:Psychiatry
Source(s) of Funding:National Institutes of Health, US Department of Health and Human Services - General Award
Start Date:09/2006


Project Title:Exome sequencing of mesial temporal lobe epilepsy with hippocampal sclerosis in parent-offspring trios
Investigator(s):Cherny SS, Sham PC
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Do de novo chromosomal abnormalities lead to sporadic biliary atresia?
Investigator(s):Cherny SS, Garcia-Barcelo MM, Tam PKH
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2014


Project Title:American Society of Human Genetics Annual Meeting; SNP-based HLA tagging, imputation, and association in adverse drug reaction of epilepsy patients from Hong Kong
Investigator(s):Cherny SS
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2015
Completion Date:10/2015


List of Research Outputs

Cherny S.S., Associate Editor (from 1997 to present), Behavior Genetics. 2015.
Cherny S.S., WONG K.L., Sham P.C., Baum L.W. and Kwan P., Exome sequencing of mesial temporal lobe epilepsy with hippocampal sclerosis in parent-offspring trios, Annual meeting of the Behavior Genetics Association. 2015.
Cherny S.S., Member, Advisory Board (from 2004 - present), Journal of Child Psychology and Psychiatry. 2015.
Cherny S.S., PLoS One. 2015.
Cherny S.S., Gui H., Kwok M., Sham P.C., Baum L.W. and Kwan P., SNP-based HLA tagging, imputation, and association in adverse drug reaction of epilepsy patients from Hong Kong, 65th Annual Meeting of the American Society of Human Genetics. 2015, 654/W.
Chiu Y.T., Wong K.L., Choi S.W., Sze M.F., Ho D.W.H., Chan L.K., Lee M.F., Man K., Cherny S.S., Yang W., Wong C.M., Sham P.C. and Ng I.O.L., Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma, Journal of Hepatology. 2016, 64(6): 1256-64.
Gui H., Kwan J., Sham P.C., Cherny S.S. and Li M., Genome-wide gene-set analysis identifies different patterns of genetic sharing across complex phenotypes, American Society of Human Genetics Annual Meeting 2015, Baltimore, USA, 6- 10 October 2015.
Haerian B.S., Baum L., Kwan P., Cherny S.S., Shin J.G., Kim S.E., Han B.G., Tan H.J., Raymond A.A., Tan C.T. and Mohamed Z., Contribution of GABRG2 Polymorphisms to Risk of Epilepsy and Febrile Seizure: a Multicenter Cohort Study and Meta-analysis, Molecular Neurobiology. 2015.
LI Y., Samartzis D., Campbell D.D., Cherny S.S., Cheung K.M.C., Luk K.D.K., Karppinen J., Song Y., Cheah K.S.E., Chan D. and Sham P.C., Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study, The Spine Journal. 2016, pii: S1529-9430(16)30095-X.
Liu W., WONG K.L., He Q.M., Wong H.M.E., Tang S.M., ZHANG R., So M.T., Wong K.K.Y., Nicholls J.M., Cherny S.S., Sham P.C., Tam P.K.H., Garcia-Barcelo M.M. and Xia H.M., Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism, BMC Medical Genetics. 2015, 16(1): 49.
Luzón-Toro B., Gui H., Tang S.M., Garcia-Barcelo M.M., Tam P.K.H., Sham P.C. and Cherny S.S., Exome sequencing reveals a high genetic heterogeneity on familial Hirschsprung disease, Scientific reports. 2015.
PORSCH R.M., Middeldorp C.M., Cherny S.S., Krapohl E., van Beijsterveldt C.E.M., Luokola A., Korhonen T., Pulkkinen L., Corley R., Rhee S., Kaprio J., Rose R.R., Hewitt J.K., Sham P.C., Plomin R., Boomsma D.I. and Barteis M., Longitudinal heritability of childhood aggression, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2016, n/a-n/a.
Tang S.M., Zhang H., Cheung Y.Y., Xu M., Ho J.C.Y., Zhou W., Cherny S.S., Zhang Y., Holmen O., Au K.W., Yu H., Xu L., Jia J., PORSCH R.M., Sun L., Xu W., Zheng H., Wong L.Y., Mu Y., Dou J., Fong H.Y., Wang S., Hong X., Dong L., Liao Y., Wang J., Lam S.M.L., Su X., Yan H., Yang M.L., Chen J., Siu D.C.W., Xie G., Woo Y.C., Wu Y., Tan K.C.B., Hveem K., Cheung B.M.Y., Zöllner S., Xu A., Eugene Chen Y., Jiamg C.Q., Jiang Y., Lam T.H., Ganesh S.K., Huo Y., Sham P.C., Lam K.S.L., Willer C.J., Tse H.F. and Gao W., Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese, Nature Communications. 2015, 6: 10206.
Tang S.M., So M.T., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Rare variants in sporadic Hirshcsprung disease patients (Abstract and Poster presentation), 65th Annual Meeting of American Society of Human Genetics, Baltimore, U.S.A. 6-10 October 2015.
Tang S.M., Gui H., Cherny S.S., Sham P.C., Tam P.K.H. and Kim J.H., Trans-ethnic meta-analysis of Hirschsprung disease (Abstract and Poster Presentation), European Human Genetics Conference (ESHG) 2016, Barcelona, Spain, 21-24 May 2016.
Waye M.M.Y., Baum L., Boyde T.R.C., Chan K.K.K., Cherny S.S., Choy F., Garcia-Barcelo M.M., Gong Z., Kagawa H., Kotaka M., Lee C.Y., Lee S.M.Y., Li H.Y., Meng H., Ng R.K., Ng T.B., Pollard J., Qi R., Shen D.W., Tam S.S.W., Tsang F.S.Y., Wasylyk B., Xue H. and Siu C.O., Journal of Biochemistry and Molecular Biology in the Post Genomic Era. 2015.
ZHANG J., ZHANG L., ZHANG Y., Yang J., GUO M., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W.G., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong W.S.R., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Cui Y., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations , Arthritis & Rheumatology. 2015, 67(11): 2966-77.
ZHAO J., Lam T.H., Jiang C., Cherny S.S., Liu B., Cheng K.K., Zhang W., Leung G.M. and Schooling C.M., A Mendelian randomization study of testosterone and cognition in men, Scientific Reports. 2016, 6: 21306.


Researcher : Cheung C

Project Title:A single cohort prospective MRI study of symptoms and brain structure maturation in autism
Investigator(s):Cheung C, McAlonan GM, Chua SE, Sham PC
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:12/2008


List of Research Outputs

Li Q., Chan S.Y., Wong K.K., Wei R., Leung Y.O., Ding A.Y., Hui T.C.K., Cheung C., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice, Behavior Genetics. Springer, 2016, 46(4): 529–537.


Researcher : Cheung TY

List of Research Outputs

Chang W.C., Cheung T.Y., Hui C.L.M., Lin J., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and risk factors of depressive symptoms in Chinese patients presenting with first-episode non-affective psychosis in Hong Kong, Schizophrenia Research. 2015.


Researcher : Ching YNE

List of Research Outputs

Chan K.W., Ching Y.N.E., Lam S.C., So H.C., Hui C.L.M., Lee H.M.E., Chang W.C. and Chen E.Y.H., Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis, Early Intervention in Psychiatry. 2015, n/a-n/a.
Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.
Lee H.M.E., Hui C.L.M., Ching Y.N.E., Lin J., Chang W.C., Chan K.W. and Chen E.Y.H., Public Stigma in China Associated With Schizophrenia, Depression, Attenuated Psychosis Syndrome, and Psychosis-Like Experiences, Psychiatry Services. 2016.


Researcher : Chiu CPY

Project Title:Paternal age effect on the outcome of first episode psychosis
Investigator(s):Chiu CPY, Chen EYH, Lam MLM, Chan KW, Hui CLM
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2009


List of Research Outputs

Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.


Researcher : Chiu SS

List of Research Outputs

Chang W.C., Lau S.K., Chiu S.S., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year clinical and functional outcome comparison between first-episode mania with psychotic features and first-episode schizophrenia, Journal of Affective Disorders. 2016, 200: 1-5.


Researcher : Choi SW

List of Research Outputs

Chiu Y.T., Wong K.L., Choi S.W., Sze M.F., Ho D.W.H., Chan L.K., Lee M.F., Man K., Cherny S.S., Yang W., Wong C.M., Sham P.C. and Ng I.O.L., Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma, Journal of Hepatology. 2016, 64(6): 1256-64.


Researcher : Chua SE

Project Title:King's/HKU Fellowship Awards 2010-11
Investigator(s):Chua SE
Department:Psychiatry
Source(s) of Funding:King's/HKU Fellowship Awards
Start Date:09/2010


List of Research Outputs

Li Q., Leung Y.O., Zhou I., Ho L.C., Kong W.K.W., Basil P., Wei R., Lam S.S.Y., Zhang X., Law A.C.K., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational Psychiatry. 2015, 5: e641.
Li Q., Chan S.Y., Wong K.K., Wei R., Leung Y.O., Ding A.Y., Hui T.C.K., Cheung C., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice, Behavior Genetics. Springer, 2016, 46(4): 529–537.


Researcher : Chung KF

Project Title:Seizure threshold of unilateral electroconvulsive therapy
Investigator(s):Chung KF, Wong SJ
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:07/2001


Project Title:Influence of a psychiatric clerkship on medical students' attitudes toward psychiatry and mental patients
Investigator(s):Chung KF
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:01/2002


Project Title:Response to moderately suprathreshold unilateral (UL) electroconvulsive therapy (ECT): an examination of possible predictors
Investigator(s):Chung KF, Irwin MG
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:06/2002


Project Title:Combined Electroacupuncture and Auricular Acupuncture for Primary Insomnia: A Randomized Controlled Trial of Dose-Response Effect
Investigator(s):Chung KF, Zhang Z, Yeung WF
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013
Completion Date:05/2016


Project Title:Incidence, persistence and remission of insomnia: a population-based 2-year longitudinal study
Investigator(s):Chung KF, Yeung WF, Ho LM
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:08/2015


List of Research Outputs

Chan M.S., Chung K.F., YUNG K.P. and Yeung W.F., Sleep in schizophrenia: A systematic review and meta-analysis of polysomnographic findings in case-control studies, Sleep Medicine Reviews. 2016.
Chung K.F., Yeung W.F., Zhang S.P., Zhang Z., Wong M.T., Lee W.K. and Chan K.W., Acupuncture for persistent insomnia associated with major depressive disorder: a randomised controlled trial, Hong Kong Medical Journal. 2016, 22 Suppl 2: 9-14.
Chung K.F., Asia-Pacific Psychiatry (Editorial Board, since 2014). 2016.
Chung K.F., Chinese Journal of Behavioral Medicine and Brain Science (Editorial Board, 2014-2018). 2016.
Chung K.F., Yu Y.M.B. and Yeung W.F., Correlates of residual fatigue in patients with major depressive disorder: The role of psychotropic medication, Journal of Affective Disorders. 2015, 186: 192-197.
Chung K.F., HO Y.Y.F. and Yeung W.F., Psychometric Comparison of the Full and Abbreviated Versions of the Dysfunctional Beliefs and Attitudes about Sleep Scale, Journal of Clinical Sleep Medicine. 2016, 12: 821-828.
Chung K.F., Research on acupuncture for insomnia: a summary of our experience, The 9th Pong Ding Yuen International Symposium on Traditional Chinese Medicine, Hong Kong, Dec, 2015.
LAM T.H., Chung K.F., Yeung W.F., Yu Y.M.B., YUNG K.P. and NG H.Y., Hypnotherapy for insomnia: A systematic review and meta-analysis of randomized controlled trials, Complementary Therapies in Medicine. 2015, 23: 719-732.
Leung S.S., Lee A.M., Wong D.F., Wong C.M., Leung K.Y., Chiang V.C., Yung W.K., Chan S.W. and Chung K.F., A brief group intervention using a cognitive behavioural approach to reduce postnatal depressive symptoms: a randomised controlled trial, Hong Kong Medical Journal. 2016, 22 Suppl 2: 4-8.
Ng T.H., Chung K.F., Lee C.T., Yeung W.F. and HO Y.Y.F., Eveningness and Its Associated Impairments in Remitted Bipolar Disorder, Behavioral Sleep Medicine. 2015, 1-15.
Ngai F.W., Wong P.W.C., Leung K.Y., Chau P.H. and Chung K.F., The Effect of Telephone-Based Cognitive-Behavioral Therapy on Postnatal Depression: A Randomized Controlled Trial, Psychotherapy and Psychosomatics. 2015, 84: 294-303.
Yeung W.F., Chung K.F., Zhang N.L.W., Zhang S.P., YUNG K.P., Chen P.X. and HO Y.Y.F., Identification of Chinese medicine syndromes in persistent insomnia associated with major depressive disorder: a latent tree analysis, Chinese Medicine. 2016, 11.
Yeung W.F., Chung K.F., HO Y.Y.F. and Ho L.M., Predictors of dropout from internet-based self-help cognitive behavioral therapy for insomnia, Behaviour Research and Therapy. 2015, 73: 19-24.
Yeung W.F., Chung K.F., Yu Y.M.B. and Lao L., Response to placebo acupuncture in insomnia: a secondary analysis of three randomized controlled trials, Sleep Medicine. 2015, 16: 1372-1376.


Researcher : Deng SJ

List of Research Outputs

Kwan S.H., Li M., Deng S.J. and Sham P.C., FAPI: Fast and Accurate P-value Imputation for genome-wide association study., European Journal of Human Genetics. 2015.


Researcher : GUI H

List of Research Outputs

LIU A., Lai P.L., GUI H., Sham M.H., Tam P.K.H., Garcia-Barcelo M.M., Hui C.C. and Ngan E.S.W., Identification of GLI mutations in patients with Hirschsprung disease that disrupt enteric nervous system development in mice, Gastroenterology. 2015, 149(7): 1837-1848.


Researcher : HO YYF

List of Research Outputs

Chung K.F., HO Y.Y.F. and Yeung W.F., Psychometric Comparison of the Full and Abbreviated Versions of the Dysfunctional Beliefs and Attitudes about Sleep Scale, Journal of Clinical Sleep Medicine. 2016, 12: 821-828.
Yeung W.F., Chung K.F., Zhang N.L.W., Zhang S.P., YUNG K.P., Chen P.X. and HO Y.Y.F., Identification of Chinese medicine syndromes in persistent insomnia associated with major depressive disorder: a latent tree analysis, Chinese Medicine. 2016, 11.


Researcher : Hui CLM

Project Title:Semantic ambiguation in Chinese patients with schizophrenia
Investigator(s):Hui CLM, Lee HME, Chan KW, Chang WC, Lin JJ, Vinas Guasch N, Chen EYH
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2016


List of Research Outputs

Chan K.W., TAM W.Y.W., LEE K.W., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., A population study of public stigma about psychosis and its contributing factors among Chinese population in Hong Kong, International Journal of Social Psychiatry. 2015, 62(3): 205-213.
Chan K.W., Chau H.S., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong, Early Intervention in Psychiatry. 2016, n/a-n/a.
Chan K.W., Ching Y.N.E., Lam S.C., So H.C., Hui C.L.M., Lee H.M.E., Chang W.C. and Chen E.Y.H., Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis, Early Intervention in Psychiatry. 2015, n/a-n/a.
Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impact of avolition and cognitive impairment on functional outcome in first-episode schizophrenia-spectrum disorder: a prospective one-year follow-up study, Schizophrenia Research. 2016, 170: 318-321.
Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.
Chang W.C., Lau F.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E., Lin J. and Chen E.Y.H., Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis, Psychiatry Research. 2016, 242: 144-149.
Chang W.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and risk factors for violent behavior in young people presenting with first-episode psychosis in Hong Kong: A 3-year follow-up study, Australian & New Zealand Journal of Psychiatry. 2015, 49: 914-922.
Chang W.C., Cheung T.Y., Hui C.L.M., Lin J., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and risk factors of depressive symptoms in Chinese patients presenting with first-episode non-affective psychosis in Hong Kong, Schizophrenia Research. 2015.
Chang W.C., Lau S.K., Chiu S.S., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year clinical and functional outcome comparison between first-episode mania with psychotic features and first-episode schizophrenia, Journal of Affective Disorders. 2016, 200: 1-5.
Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].
Chen S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Self-stigma and affiliate stigma in first-episode psychosis patients and their caregivers, Social Psychiatry and Psychiatric Epidemiology. 2016, 1-7.
De Deyne S., Elvevåg B., Hui C.L.M., Poon W.Y.V. and Chen E.Y.H., Rich semantic networks applied to schizophrenia: A new framework, Schizophrenia Research. 2016.
Fusar-Poli P., Cappucciati M., Bonoldi I., Hui C.L.M., Rutigliano G., Stahl D.R., Borgwardt S., Politi P., Mishara A.L., Lawrie S.M., Carpenter W.T. and McGuire P.K., Prognosis of Brief Psychotic Episodes, JAMA Psychiatry. 2016, 73 (3): 211.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Lin J., Xu J. and Chen E.Y.H., Delusional disorder and schizophrenia: a comparison of the neurocognitive and clinical characteristics in first-episode patients, Psychological Medicine. 2015.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W. and Chen E.Y.H., Letter to the Editor: Comparing delusional disorder and schizophrenia: a comment on Hui et al. (2015) – a reply, Psychological Medicine. 2016, 46: 1561-1562.
Hui C.L.M., Poon W.Y.V., Kwok S.K.V., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and predictors of medication non-adherence among Chinese patients with first-episode psychosis, Psychiatry Research. 2015, 228 (3): 680-687.
Hui C.L.M., Poon W.Y.V., Ko W.T., Miao H.Y., Chang W.C., Lee H.M.E., Chan K.W., Lin J. and Chen E.Y.H., Risk factors for antipsychotic medication non-adherence behaviors and attitudes in adult-onset psychosis, Schizophrenia Research. 2016.
Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Demographic correlates of medication knowledge in Hong Kong early psychosis patients, Early Intervention in Psychiatry. 2016.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Psychosis patients’ knowledge, adherence and attitudes towards the naming of antipsychotic medication in Hong Kong, Early Interv Psychiatry. 2015, 9 (5): 422-427.
Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.
Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Lin J. and Chen E.Y.H., Letter to the Editor: Comparison of cognitive functions, pre-morbid conditions and clinical characteristics between brief psychotic disorder and schizophrenia, Psychological Medicine. 2016, 46(9): 1-3.
Lee H.M.E., Hui C.L.M., Ching Y.N.E., Lin J., Chang W.C., Chan K.W. and Chen E.Y.H., Public Stigma in China Associated With Schizophrenia, Depression, Attenuated Psychosis Syndrome, and Psychosis-Like Experiences, Psychiatry Services. 2016.
Lee W.Y., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., A systematic review on definitions and assessments of psychotic-like experiences, Early Interv Psychiatry. 2016, 10 (1): 3-16.
Lin J., Chan K.W., Lee H.M.E., Chang W.C., Tse M.A., Su W.W., Sham P.C., Hui C.L.M., Joe G.M., Chan C.L.W., Khong P.L., So K.F., Honer W. and Chen E.Y.H., Aerobic Exercise and Yoga Improve Neuro-Cognitive Function in Women with Early Psychosis: Effects of a Randomized Controlled Trial, NPJ Schizophrenia. 2015.
Longenecker J., Hui C.L.M., Chen E.Y.H. and Elvevag B., Concepts of ‘self’ in delusion resolution, Schizophrenia Research: Cognition. 2016, 3: 8-10.
Tong A.C., Lin J., Cheung V.Y., Lau K.M., Chang W.C., Chan K.W., Hui C.L.M., Lee H.M.E. and Chen E.Y.H., A Low-Intensity Mindfulness-Based Intervention for Mood Symptoms in People with Early Psychosis: Development and Pilot Evaluation, Clin Psychol Psychother. 2015.


Researcher : Hui TCK

List of Research Outputs

Li Q., Chan S.Y., Wong K.K., Wei R., Leung Y.O., Ding A.Y., Hui T.C.K., Cheung C., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice, Behavior Genetics. Springer, 2016, 46(4): 529–537.


Researcher : Hung BKG

List of Research Outputs

Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].


Researcher : Jim TT

List of Research Outputs

Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.


Researcher : Ko WT

List of Research Outputs

Hui C.L.M., Poon W.Y.V., Ko W.T., Miao H.Y., Chang W.C., Lee H.M.E., Chan K.W., Lin J. and Chen E.Y.H., Risk factors for antipsychotic medication non-adherence behaviors and attitudes in adult-onset psychosis, Schizophrenia Research. 2016.


Researcher : Kong WKW

List of Research Outputs

Li Q., Leung Y.O., Zhou I., Ho L.C., Kong W.K.W., Basil P., Wei R., Lam S.S.Y., Zhang X., Law A.C.K., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational Psychiatry. 2015, 5: e641.


Researcher : Kwan SH

Project Title:Statistical method for detecting disease associations with rare genetic variants, with application to analysis of osteoporosis genetic data
Investigator(s):Kwan SH, Li M, Sham PC
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:06/2014
Completion Date:12/2015


List of Research Outputs

Kwan S.H., Li M., Deng S.J. and Sham P.C., FAPI: Fast and Accurate P-value Imputation for genome-wide association study., European Journal of Human Genetics. 2015.


Researcher : Kwong WY

List of Research Outputs

Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.


Researcher : LAM TH

List of Research Outputs

LAM T.H., Chung K.F., Yeung W.F., Yu Y.M.B., YUNG K.P. and NG H.Y., Hypnotherapy for insomnia: A systematic review and meta-analysis of randomized controlled trials, Complementary Therapies in Medicine. 2015, 23: 719-732.


Researcher : LEE KW

List of Research Outputs

Chan K.W., TAM W.Y.W., LEE K.W., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., A population study of public stigma about psychosis and its contributing factors among Chinese population in Hong Kong, International Journal of Social Psychiatry. 2015, 62(3): 205-213.


Researcher : LI Y

List of Research Outputs

LI Y., Samartzis D., Campbell D.D., Cherny S.S., Cheung K.M.C., Luk K.D.K., Karppinen J., Song Y., Cheah K.S.E., Chan D. and Sham P.C., Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study, The Spine Journal. 2016, pii: S1529-9430(16)30095-X.
XIONG C., LI Y., Rai F.M., Sham P.C., ZHANG Y., Song Y., Cheah K.S.E. and Chan D., Genetic contribution to intervertebral discs integrity maintenance in mouse model, Hong Kong Inter-University Postgraduate Symposium in Biochemical Sciences. 2016.


Researcher : Lam SSY

List of Research Outputs

Li Q., Leung Y.O., Zhou I., Ho L.C., Kong W.K.W., Basil P., Wei R., Lam S.S.Y., Zhang X., Law A.C.K., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational Psychiatry. 2015, 5: e641.


Researcher : Lau CK

List of Research Outputs

Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Demographic correlates of medication knowledge in Hong Kong early psychosis patients, Early Intervention in Psychiatry. 2016.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Psychosis patients’ knowledge, adherence and attitudes towards the naming of antipsychotic medication in Hong Kong, Early Interv Psychiatry. 2015, 9 (5): 422-427.


Researcher : Lau EYY

Project Title:Sleep quality, hall residency, and mental health in university students
Investigator(s):Lau EYY, Hui HCC, Ng CW
Department:Psychology
Source(s) of Funding:Wu Jieh-Yee Research Fund
Start Date:11/2010


Project Title:Effects of Brief Daytime Napping and Caffeine Consumption on Declarative and Procedural Memory in Healthy Elderly
Investigator(s):Lau EYY
Department:Psychology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2013
Completion Date:08/2015


Project Title:What makes poor sleepers anxious and depressed? Testing the mediating role of cognitive deficits between poor sleep and anxiety and depressive disorders
Investigator(s):Lau EYY
Department:Psychology
Source(s) of Funding:Health and Medical Research Fund - Mini Grant
Start Date:01/2014


Project Title:Insomnia as a risk factor for depression: the role of sleep in emotional processing
Investigator(s):Lau EYY, Tseng CH
Department:Psychology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2014
Completion Date:08/2015


Project Title:Effects of sleep disturbances on disrupted affective cognition in individuals with depression
Investigator(s):Lau EYY, Tseng CH, Chung KF, Chan CS
Department:Psychology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2015


Project Title:Sleep and Risk-related Decision-making in Adolescents and Young Adults
Investigator(s):Lau EYY, Lee TMC, Tseng CH
Department:Psychology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016
Completion Date:08/2015


List of Research Outputs

Lau E.Y.Y., CHOI E.W.M., LAI E.S.K., LAU N.T., AU C.T., Yung W.H. and LI A.M., Working memory impairment and its associated sleep-related respiratory parameters in children with obstructive sleep apnea, Sleep Medicine. 2015, 16: 1109-1115.


Researcher : Lau FC

List of Research Outputs

Chang W.C., Lau F.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E., Lin J. and Chen E.Y.H., Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis, Psychiatry Research. 2016, 242: 144-149.


Researcher : Lau KM

List of Research Outputs

Tong A.C., Lin J., Cheung V.Y., Lau K.M., Chang W.C., Chan K.W., Hui C.L.M., Lee H.M.E. and Chen E.Y.H., A Low-Intensity Mindfulness-Based Intervention for Mood Symptoms in People with Early Psychosis: Development and Pilot Evaluation, Clin Psychol Psychother. 2015.


Researcher : Lau KW

List of Research Outputs

Lau K.W., Leung M.K., Chan C.C.H., Wong S.S.Y. and Lee T.M.C., Can the neural–cortisol association be moderated by experience-induced changes in awareness?, Scientific Reports. 2015, 5: 16620.
Lau K.W., Leung M.K., Lee T.M.C. and Law A.C.K., Resting-state abnormalities in amnestic mild cognitive impairment: a meta-analysis, Translational Psychiatry. 2016, 6: e790.


Researcher : Lau SK

List of Research Outputs

Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.
Chang W.C., Lau S.K., Chiu S.S., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year clinical and functional outcome comparison between first-episode mania with psychotic features and first-episode schizophrenia, Journal of Affective Disorders. 2016, 200: 1-5.


Researcher : Law ACK

Project Title:Basic Neuroscience research on dementing disorders
Investigator(s):Law ACK
Department:Psychiatry
Source(s) of Funding:Chow Tai Fook Charity Foundation Limited
Start Date:07/2015


List of Research Outputs

Lau K.W., Leung M.K., Lee T.M.C. and Law A.C.K., Resting-state abnormalities in amnestic mild cognitive impairment: a meta-analysis, Translational Psychiatry. 2016, 6: e790.
Li Q., Leung Y.O., Zhou I., Ho L.C., Kong W.K.W., Basil P., Wei R., Lam S.S.Y., Zhang X., Law A.C.K., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational Psychiatry. 2015, 5: e641.


Researcher : Law CW

List of Research Outputs

Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.


Researcher : Lee AM

Project Title:Prevalence and risk factors for paternal depression and anxiety in the antenatal period
Investigator(s):Lee AM, Chung KF, Fong DYT, Law ACK, Leung KY
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:02/2009


List of Research Outputs

Lee C.F., Ho J.W.C., Fong D.Y.T., Macfarlane D.J., Cerin E., Lee A.M., Leung S., Taylor A. and Cheng K.K., Effects of Dietary and Physical Activity Interventions on Health-Related Quality of Life Outcomes in Colorectal Cancer Survivors, In: Wan Chong Hua, 2nd World Chinese Quality of Life Conference cum 7th National Quality of Life Conference. 2016, 73.
Leung S.S., Lee A.M., Wong D.F., Wong C.M., Leung K.Y., Chiang V.C., Yung W.K., Chan S.W. and Chung K.F., A brief group intervention using a cognitive behavioural approach to reduce postnatal depressive symptoms: a randomised controlled trial, Hong Kong Medical Journal. 2016, 22 Suppl 2: 4-8.


Researcher : Lee HME

Project Title:FitMind exercise for improving cognition: A train-the-trainer program for mental health caregivers in the community
Investigator(s):Lee HME, Chen EYH, Chang WC, Chan KW, Hui CLM, Wong GHY, Tse MA
Department:Psychiatry
Source(s) of Funding:Health Care and Promotion Fund - Research Grant Projects
Start Date:09/2013


Project Title:Biomarkers for treatment response in first-episode psychosis
Investigator(s):Lee HME, Hui CLM, Lin JJ, Chang WC, Chan KW, Chen EYH
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2015


List of Research Outputs

CHUI S.L.C., WONG Y.S., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Potential association between the use of oral fluoroquinolones and acute neuropsychiatric disorders in Hong Kong: A self-controlled case series study, The ISPE's 9th Asian Conference on Pharmacoepidemiology, Bangkok, Thailand November 14-16, 2015.
Chan K.W., TAM W.Y.W., LEE K.W., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., A population study of public stigma about psychosis and its contributing factors among Chinese population in Hong Kong, International Journal of Social Psychiatry. 2015, 62(3): 205-213.
Chan K.W., Chau H.S., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., Long term effect of early intervention service on duration of untreated psychosis in youth and adult population in Hong Kong, Early Intervention in Psychiatry. 2016, n/a-n/a.
Chan K.W., Ching Y.N.E., Lam S.C., So H.C., Hui C.L.M., Lee H.M.E., Chang W.C. and Chen E.Y.H., Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis, Early Intervention in Psychiatry. 2015, n/a-n/a.
Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Impact of avolition and cognitive impairment on functional outcome in first-episode schizophrenia-spectrum disorder: a prospective one-year follow-up study, Schizophrenia Research. 2016, 170: 318-321.
Chang W.C., Kwong W.Y., Chan H.K.G., Jim T.T., Lau S.K., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prediction of functional remission in first-episode psychosis: 12-month follow-up of the randomized-controlled trial on extended early intervention in Hong Kong, Schizophrenia Research. 2016, 173: 79-83.
Chang W.C., Lau F.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E., Lin J. and Chen E.Y.H., Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis, Psychiatry Research. 2016, 242: 144-149.
Chang W.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and risk factors for violent behavior in young people presenting with first-episode psychosis in Hong Kong: A 3-year follow-up study, Australian & New Zealand Journal of Psychiatry. 2015, 49: 914-922.
Chang W.C., Cheung T.Y., Hui C.L.M., Lin J., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and risk factors of depressive symptoms in Chinese patients presenting with first-episode non-affective psychosis in Hong Kong, Schizophrenia Research. 2015.
Chang W.C., Lau S.K., Chiu S.S., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Three-year clinical and functional outcome comparison between first-episode mania with psychotic features and first-episode schizophrenia, Journal of Affective Disorders. 2016, 200: 1-5.
Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].
Chen S.M., Chang W.C., Hui C.L.M., Chan K.W., Lee H.M.E. and Chen E.Y.H., Self-stigma and affiliate stigma in first-episode psychosis patients and their caregivers, Social Psychiatry and Psychiatric Epidemiology. 2016, 1-7.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Lin J., Xu J. and Chen E.Y.H., Delusional disorder and schizophrenia: a comparison of the neurocognitive and clinical characteristics in first-episode patients, Psychological Medicine. 2015.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W. and Chen E.Y.H., Letter to the Editor: Comparing delusional disorder and schizophrenia: a comment on Hui et al. (2015) – a reply, Psychological Medicine. 2016, 46: 1561-1562.
Hui C.L.M., Poon W.Y.V., Kwok S.K.V., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and predictors of medication non-adherence among Chinese patients with first-episode psychosis, Psychiatry Research. 2015, 228 (3): 680-687.
Hui C.L.M., Poon W.Y.V., Ko W.T., Miao H.Y., Chang W.C., Lee H.M.E., Chan K.W., Lin J. and Chen E.Y.H., Risk factors for antipsychotic medication non-adherence behaviors and attitudes in adult-onset psychosis, Schizophrenia Research. 2016.
Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Demographic correlates of medication knowledge in Hong Kong early psychosis patients, Early Intervention in Psychiatry. 2016.
Lau C.K., Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W. and Chen E.Y.H., Psychosis patients’ knowledge, adherence and attitudes towards the naming of antipsychotic medication in Hong Kong, Early Interv Psychiatry. 2015, 9 (5): 422-427.
Lee H.M.E., So H.C. and Chen E.Y.H., Admission Rates and Psychiatric Beds in Hong Kong, 1999–2014: A Population-Based Study, Psychiatric Services. 2016, 67: 579-579.
Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.
Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Lin J. and Chen E.Y.H., Letter to the Editor: Comparison of cognitive functions, pre-morbid conditions and clinical characteristics between brief psychotic disorder and schizophrenia, Psychological Medicine. 2016, 46(9): 1-3.
Lee H.M.E., Hui C.L.M., Ching Y.N.E., Lin J., Chang W.C., Chan K.W. and Chen E.Y.H., Public Stigma in China Associated With Schizophrenia, Depression, Attenuated Psychosis Syndrome, and Psychosis-Like Experiences, Psychiatry Services. 2016.
Lee W.Y., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., A systematic review on definitions and assessments of psychotic-like experiences, Early Interv Psychiatry. 2016, 10 (1): 3-16.
Lin J., Chan K.W., Lee H.M.E., Chang W.C., Tse M.A., Su W.W., Sham P.C., Hui C.L.M., Joe G.M., Chan C.L.W., Khong P.L., So K.F., Honer W. and Chen E.Y.H., Aerobic Exercise and Yoga Improve Neuro-Cognitive Function in Women with Early Psychosis: Effects of a Randomized Controlled Trial, NPJ Schizophrenia. 2015.
Tong A.C., Lin J., Cheung V.Y., Lau K.M., Chang W.C., Chan K.W., Hui C.L.M., Lee H.M.E. and Chen E.Y.H., A Low-Intensity Mindfulness-Based Intervention for Mood Symptoms in People with Early Psychosis: Development and Pilot Evaluation, Clin Psychol Psychother. 2015.
WONG Y.S., Wong I.C.K., Chui S.L.C., Lee H.M.E., Chang W.C., Chen E.Y.H., Leung W.K. and Chan E.W., Association Between Acute Neuropsychiatric Events and Helicobacter pylori Therapy Containing Clarithromycin , JAMA Internal Medicine. 2016, 176(6): 828-834.
WONG Y.S., CHUI S.L.C., Lee H.M.E., Chang W.C., Chen E.Y.H., Wong I.C.K. and Chan E.W., Neuropsychiatric disorders associated with the use of helicobacterpylori eradication therapy containing-clarithromyclin_self-controlled case series, The ISPE's 9th Asian Conference on Pfharmacoepidemiology, Bangkok, Thailand, November 14-16, 2015.


Researcher : Lee PWH

Project Title:A study of risk factors for exposure to AIDS in high risk adolescent Chinese females
Investigator(s):Lee WHP
Department:Psychiatry
Source(s) of Funding:Council for the AIDS Trust Fund - General Award
Start Date:04/1997


Project Title:Psychological adjustment and stresses of nurses working in acute hospital
Investigator(s):Lee WHP
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:06/1997


Project Title:The psychosocial outcomes and well-being of living related donors involved in liver transplantation surgery: a follow-up study of risk factors, resilience, and outcome predictors
Investigator(s):Lee WHP, Fan ST, Fung ASM
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:11/2003




Researcher : Lee WY

List of Research Outputs

Lee W.Y., Chan K.W., Chang W.C., Lee H.M.E., Hui C.L.M. and Chen E.Y.H., A systematic review on definitions and assessments of psychotic-like experiences, Early Interv Psychiatry. 2016, 10 (1): 3-16.


Researcher : Leung WG

List of Research Outputs

Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.


Researcher : Leung YO

List of Research Outputs

Li Q., Leung Y.O., Zhou I., Ho L.C., Kong W.K.W., Basil P., Wei R., Lam S.S.Y., Zhang X., Law A.C.K., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational Psychiatry. 2015, 5: e641.
Li Q., Chan S.Y., Wong K.K., Wei R., Leung Y.O., Ding A.Y., Hui T.C.K., Cheung C., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice, Behavior Genetics. Springer, 2016, 46(4): 529–537.


Researcher : Li M

Project Title:Statistical method to identify risk genes of complex diseases based on functional gene sets and networks, with a genetic data mining application to hepatocellular carcinoma
Investigator(s):Li M, Sham PC, Ng IOL, Kwan SH
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2014


Project Title:A method and tool to combine statistics and functional evidences for characterizing cancer-driver genes and pathways in exome sequencing study
Investigator(s):Li M, Kwan SH, Ng IOL, Sham PC
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2014
Completion Date:09/2016


Project Title:2014 World Congress of Psychiatric Genetics; Gene- And Pathway-Based Association Analyses of Shared Psychiatric Genomics Consortium Data
Investigator(s):Li M
Department:Psychiatry
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2014


Project Title:Prioritizing genes on disease susceptibility by comprehensive biological features
Investigator(s):Li M, Sham PC
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2015


Project Title:Development of multivariate gene-based association analysis approaches for endophenotypes of complex diseases and their application to genetic mapping in a Chinese schizophrenia sample
Investigator(s):Li M, Sham PC, Kwan SH
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2015


Project Title:Haplotype-based gene expression prediction and its application in genome-wide association studies
Investigator(s):Li M, Sham PC, Ying D
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2016


List of Research Outputs

Deng J.E., Sham P.C. and Li M., SNPTracker: A Swift Tool for Comprehensive Tracking and Unifying dbSNP rs IDs and Genomic Coordinates of Massive Sequence Variants, G3: Genes|Genomes|Genetics. 2015, 6: 205-207.
Gui H., Kwan J., Sham P.C., Cherny S.S. and Li M., Genome-wide gene-set analysis identifies different patterns of genetic sharing across complex phenotypes, American Society of Human Genetics Annual Meeting 2015, Baltimore, USA, 6- 10 October 2015.
Gui H., Li M., Baum L., Kwan P. and Cherny S.S., Patterns of epilepsy-schizophrenia genetic correlation and sharing revealed by secondary analyses of GWAS data, 11th Asian & Oceanian Epilepsy Congress 2016, Hong Kong, China, 13-16 May 2016.. 2016.
Kwan S.H., Li M., Deng S.J. and Sham P.C., FAPI: Fast and Accurate P-value Imputation for genome-wide association study., European Journal of Human Genetics. 2015.
LI J., Song Y., Sham P.C. and Li M., KGGSeq: a rapid and robust framework for large-scale whole genome sequencing downstream analysis with integrative functions, Hong Kong Inter-University Postgraduate Symposium in Biochemical Sciences. 2016.
LI J., Sham P.C., Song Y. and Li M., SPS: A Simulation Tool for Calculating Power of Set-Based Genetic Association Tests, Genetic Epidemiology. 2015, 39: 395-397.
Liu C., Saffen D., Schulze T.G., Burmeister M., Sham P.C., Yao Y.G., Kuo P.H., Chen C., An Y., Dai J., Yue W., Li M., Xue H., Su B., Chen L., Shi Y., Qiao M., Liu T., Xia K. and Chan R.C.K., Psychiatric genetics in China: achievements and challenges, Molecular Psychiatry. 2016, 21: 4-9.
Wang Q., Li M., Yang Z., Hu X., Wu H.M., Ni P., Ren H., Deng W., Li M., Ma X., Guo W., Zhao L., Wang Y., Xiang B., Lei W., Sham P.C. and Li T., Increased co-expression of genes harboring the damaging de novo mutations in Chinese schizophrenic patients during prenatal development, Scientific Reports. 2015, 5: 18209.
Wang Q., Cheng W., Li M., Ren H., Hu X., Deng W., Ma X., Zhao L., Wang Y., Xiang B., Wu H.M., Sham P.C., Feng J. and Li T., The CHRM3 gene is implicated in abnormal thalamo-orbital frontal cortex functional connectivity in first-episode treatment-naive patients with schizophrenia, Psychological Medicine. 2016, 46: 1523-1534.


Researcher : Li Q

Project Title:Serotonin transporter (Sert) gene silence in the frontal cortex by in utero electroporation: a promising platform for generating a novel mouse model for neurodevelopmental psychiatric disorders
Investigator(s):Li Q, Chen EYH, Cheung MCH, Lee HME, Chan SY
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:01/2014


List of Research Outputs

CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., Joint neuroscience symposium on Nature and Nurture in Brain Functions: First Runner up Oral Presentation, title of the presentation--LRRC7 mutant mice model developmental emotional dysregulation, The State Key Laboratory of Brain & Cognitive Sciences, HKU and Hong Kong Society of Neurosciences. 2016.
Li Q., Leung Y.O., Zhou I., Ho L.C., Kong W.K.W., Basil P., Wei R., Lam S.S.Y., Zhang X., Law A.C.K., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational Psychiatry. 2015, 5: e641.
Li Q., Chan S.Y., Wong K.K., Wei R., Leung Y.O., Ding A.Y., Hui T.C.K., Cheung C., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice, Behavior Genetics. Springer, 2016, 46(4): 529–537.


Researcher : Li SP

List of Research Outputs

Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.


Researcher : Li YK

List of Research Outputs

Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.


Researcher : Lin J

Project Title:Mindfulness-based intervention for patients with psychosis: A RCT and Neuroimaging study
Investigator(s):Lin JJ, Chen EYH, Lee HME, Geng X, Chang WC, Chan KW, Hui CLM, Tong CY
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:07/2016


List of Research Outputs

Chang W.C., Lau F.C., Chan S.I., Hui C.L.M., Chan K.W., Lee H.M.E., Lin J. and Chen E.Y.H., Premorbid, clinical and cognitive correlates of primary negative symptoms in first-episode psychosis, Psychiatry Research. 2016, 242: 144-149.
Chang W.C., Cheung T.Y., Hui C.L.M., Lin J., Chan K.W., Lee H.M.E. and Chen E.Y.H., Rate and risk factors of depressive symptoms in Chinese patients presenting with first-episode non-affective psychosis in Hong Kong, Schizophrenia Research. 2015.
Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Lin J., Xu J. and Chen E.Y.H., Delusional disorder and schizophrenia: a comparison of the neurocognitive and clinical characteristics in first-episode patients, Psychological Medicine. 2015.
Hui C.L.M., Poon W.Y.V., Ko W.T., Miao H.Y., Chang W.C., Lee H.M.E., Chan K.W., Lin J. and Chen E.Y.H., Risk factors for antipsychotic medication non-adherence behaviors and attitudes in adult-onset psychosis, Schizophrenia Research. 2016.
Lee H.M.E., Hui C.L.M., Chang W.C., Chan K.W., Lin J. and Chen E.Y.H., Letter to the Editor: Comparison of cognitive functions, pre-morbid conditions and clinical characteristics between brief psychotic disorder and schizophrenia, Psychological Medicine. 2016, 46(9): 1-3.
Lee H.M.E., Hui C.L.M., Ching Y.N.E., Lin J., Chang W.C., Chan K.W. and Chen E.Y.H., Public Stigma in China Associated With Schizophrenia, Depression, Attenuated Psychosis Syndrome, and Psychosis-Like Experiences, Psychiatry Services. 2016.
Lin J., Chan K.W., Lee H.M.E., Chang W.C., Tse M.A., Su W.W., Sham P.C., Hui C.L.M., Joe G.M., Chan C.L.W., Khong P.L., So K.F., Honer W. and Chen E.Y.H., Aerobic Exercise and Yoga Improve Neuro-Cognitive Function in Women with Early Psychosis: Effects of a Randomized Controlled Trial, NPJ Schizophrenia. 2015.
Tong A.C., Lin J., Cheung V.Y., Lau K.M., Chang W.C., Chan K.W., Hui C.L.M., Lee H.M.E. and Chen E.Y.H., A Low-Intensity Mindfulness-Based Intervention for Mood Symptoms in People with Early Psychosis: Development and Pilot Evaluation, Clin Psychol Psychother. 2015.


Researcher : Lin JJ

Project Title:Mindfulness-based intervention for patients with psychosis: A RCT and Neuroimaging study
Investigator(s):Lin JJ, Chen EYH, Lee HME, Geng X, Chang WC, Chan KW, Hui CLM, Tong CY
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:07/2016


List of Research Outputs

Lee H.M.E., Hui C.L.M., Lin J.J., Ching Y.N.E., Li S.P., Leung W.G., Chang W.C., Chan K.W. and Chen E.Y.H., Incidence of hospitalization and its associated factor in first episode psychosis in Hong Kong, Early Interv Psychiatry. 2016, 10 (3): 263-266.


Researcher : Lui SY

List of Research Outputs

Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].


Researcher : McAlonan GM

Project Title:Preventing schizophrenia-like phenotype in the mouse model
Investigator(s):McAlonan GM, Chua SE, Lam SSY, Wang Y, Li Q
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2010


Project Title:MRI aided diagnosis of autism
Investigator(s):McAlonan GM, Cheung C, Chua SE
Department:Psychiatry
Source(s) of Funding:Seed Fund for Basic Research
Start Date:01/2011


List of Research Outputs

CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., Joint neuroscience symposium on Nature and Nurture in Brain Functions: First Runner up Oral Presentation, title of the presentation--LRRC7 mutant mice model developmental emotional dysregulation, The State Key Laboratory of Brain & Cognitive Sciences, HKU and Hong Kong Society of Neurosciences. 2016.
Li Q., Leung Y.O., Zhou I., Ho L.C., Kong W.K.W., Basil P., Wei R., Lam S.S.Y., Zhang X., Law A.C.K., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational Psychiatry. 2015, 5: e641.
Li Q., Chan S.Y., Wong K.K., Wei R., Leung Y.O., Ding A.Y., Hui T.C.K., Cheung C., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice, Behavior Genetics. Springer, 2016, 46(4): 529–537.


Researcher : NG HY

List of Research Outputs

LAM T.H., Chung K.F., Yeung W.F., Yu Y.M.B., YUNG K.P. and NG H.Y., Hypnotherapy for insomnia: A systematic review and meta-analysis of randomized controlled trials, Complementary Therapies in Medicine. 2015, 23: 719-732.


Researcher : Ng ML

Project Title:Violence on male genitalia - a ten year review of cases in Hong Kong
Investigator(s):Ng ML
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:05/2002




Researcher : PORSCH RM

List of Research Outputs

PORSCH R.M., Middeldorp C.M., Cherny S.S., Krapohl E., van Beijsterveldt C.E.M., Luokola A., Korhonen T., Pulkkinen L., Corley R., Rhee S., Kaprio J., Rose R.R., Hewitt J.K., Sham P.C., Plomin R., Boomsma D.I. and Barteis M., Longitudinal heritability of childhood aggression, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2016, n/a-n/a.
Tang S.M., Zhang H., Cheung Y.Y., Xu M., Ho J.C.Y., Zhou W., Cherny S.S., Zhang Y., Holmen O., Au K.W., Yu H., Xu L., Jia J., PORSCH R.M., Sun L., Xu W., Zheng H., Wong L.Y., Mu Y., Dou J., Fong H.Y., Wang S., Hong X., Dong L., Liao Y., Wang J., Lam S.M.L., Su X., Yan H., Yang M.L., Chen J., Siu D.C.W., Xie G., Woo Y.C., Wu Y., Tan K.C.B., Hveem K., Cheung B.M.Y., Zöllner S., Xu A., Eugene Chen Y., Jiamg C.Q., Jiang Y., Lam T.H., Ganesh S.K., Huo Y., Sham P.C., Lam K.S.L., Willer C.J., Tse H.F. and Gao W., Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese, Nature Communications. 2015, 6: 10206.


Researcher : Poon WYV

List of Research Outputs

De Deyne S., Elvevåg B., Hui C.L.M., Poon W.Y.V. and Chen E.Y.H., Rich semantic networks applied to schizophrenia: A new framework, Schizophrenia Research. 2016.
Hui C.L.M., Poon W.Y.V., Kwok S.K.V., Chang W.C., Chan K.W., Lee H.M.E. and Chen E.Y.H., Prevalence and predictors of medication non-adherence among Chinese patients with first-episode psychosis, Psychiatry Research. 2015, 228 (3): 680-687.
Hui C.L.M., Poon W.Y.V., Ko W.T., Miao H.Y., Chang W.C., Lee H.M.E., Chan K.W., Lin J. and Chen E.Y.H., Risk factors for antipsychotic medication non-adherence behaviors and attitudes in adult-onset psychosis, Schizophrenia Research. 2016.


Researcher : Sham PC

Project Title:Replication study of susceptibility genes for colorectal cancer
Investigator(s):Sham PC, Ho JWC, Cheng KK
Department:LKS Medical Faculty
Source(s) of Funding:Small Project Funding
Start Date:10/2007


Project Title:Partner State Key Laboratory of Brain and Cognitive Sciences
Investigator(s):Sham PC, So KF, Tan L
Department:Centre for Genomic Sciences
Source(s) of Funding:Matching Fund for State Key Laboratory (SKL)
Start Date:10/2008


Project Title:Visiting Research Professors Scheme 2009-10
Investigator(s):Sham PC
Department:LKS Medical Faculty
Source(s) of Funding:Visiting Research Professors Scheme
Start Date:09/2009


Project Title:Method and Software for Personal Risk Profiling of Complex Diseases
Investigator(s):Sham PC, Cherny SS, Garcia-Barcelo MM, Kung AWC, Li M, Yang W
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012
Completion Date:12/2015


Project Title:Bioinformatics tools for identifying disease loci from exome sequencing data
Investigator(s):Sham PC, Cherny SS, Garcia-Barcelo MM, Li M, Yang W
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2013


Project Title:Genomics
Investigator(s):Sham PC, Chin FYL, Leung FCC
Department:LKS Medical Faculty
Source(s) of Funding:Seed Funding for Strategic Research Theme
Start Date:06/2013


Project Title:Cross Cultural Differences in Biased Cognition
Investigator(s):Sham PC, Chen EYH, Toulopoulou T
Department:LKS Medical Faculty
Source(s) of Funding:ESRC/RGC Joint Research Scheme
Start Date:09/2013


Project Title:Statistical methods for characterizing the genetic component of polygenic diseases
Investigator(s):Sham PC, Cherny SS
Department:Psychiatry
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:Mutational spectrum for dilated cardiomyopathy in Hong Kong
Investigator(s):Sham PC, Tse HF, Cherny SS, Garcia-Barcelo MM, Tang SM, Li M
Department:Centre for Genomic Sciences
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:04/2014


Project Title:A novel computational framework to identify transcription factor-DNA interaction for cancer genomics
Investigator(s):Sham PC, Yao KM, Wong MP, Wang JJ
Department:LKS Medical Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:08/2014


Project Title:Schizophrenia-related de novo and compound heterozygous mutations
Investigator(s):Sham PC, Chen EYH, Chang WC, Chan KW, Lee HME, Cherny SS, Li M
Department:LKS Medical Faculty
Source(s) of Funding:NSFC/RGC Joint Research Scheme
Start Date:01/2015


Project Title:Method and software tool for estimating and dissecting the heritability of complex diseases
Investigator(s):Sham PC, Cherny SS, Li M
Department:LKS Medical Faculty
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2015


List of Research Outputs

Chen H., Zhou X., Wang J., Wang X., Liu L., Wu S., Li T., Chen S., Yang J., Sham P.C., Zhu G., Zhang X. and Wang B., Exome Sequencing and Gene Prioritization Correct Misdiagnosis in a Chinese Kindred with Familial Amyloid Polyneuropathy, Scientific Reports. Nature Publishing Group, 2016.
Chiu P.W., Chan Q., Lui S.Y., Hung K.S.Y., Aman R.R.A.R., Chan R.C.K., Sham P.C., Cheung E.F.C., Edden R.A.E. and Mak H.K.F., Reduced Gamma-amino Butyric Acid And Elevated Glu/gln Complex In The Anterior Cingulate Cortex Of Medicated Schizophrenic Patients, The 24th Annual Meeting of ISMRM, Singapore. 2016, 4133.
Chiu Y.T., Wong K.L., Choi S.W., Sze M.F., Ho D.W.H., Chan L.K., Lee M.F., Man K., Cherny S.S., Yang W., Wong C.M., Sham P.C. and Ng I.O.L., Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma, Journal of Hepatology. 2016, 64(6): 1256-64.
Deng J.E., Sham P.C. and Li M., SNPTracker: A Swift Tool for Comprehensive Tracking and Unifying dbSNP rs IDs and Genomic Coordinates of Massive Sequence Variants, G3: Genes|Genomes|Genetics. 2015, 6: 205-207.
Hui C.L.M., Chiu C.P.Y., Li Y.K., Law C.W., Chang W.C., Chan K.W., Lee H.M.E., Sham P.C. and Chen E.Y.H., The Effect of Paternal Age on Relapse in First-Episode Schizophrenia, Canadian Journal of Psychiatry. 2015, 60 (8): 346-353.
LI J., Sham P.C., Song Y. and Li M., SPS: A Simulation Tool for Calculating Power of Set-Based Genetic Association Tests, Genetic Epidemiology. 2015, 39: 395-397.
Li Q., Leung Y.O., Zhou I., Ho L.C., Kong W.K.W., Basil P., Wei R., Lam S.S.Y., Zhang X., Law A.C.K., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Dietary supplementation with n-3 fatty acids from weaning limits brain biochemistry and behavioural changes elicited by prenatal exposure to maternal inflammation in the mouse model, Translational Psychiatry. 2015, 5: e641.
Li Q., Chan S.Y., Wong K.K., Wei R., Leung Y.O., Ding A.Y., Hui T.C.K., Cheung C., Chua S.E., Sham P.C., Wu E.X. and McAlonan G.M., Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice, Behavior Genetics. Springer, 2016, 46(4): 529–537.
Lin J., Chan K.W., Lee H.M.E., Chang W.C., Tse M.A., Su W.W., Sham P.C., Hui C.L.M., Joe G.M., Chan C.L.W., Khong P.L., So K.F., Honer W. and Chen E.Y.H., Aerobic Exercise and Yoga Improve Neuro-Cognitive Function in Women with Early Psychosis: Effects of a Randomized Controlled Trial, NPJ Schizophrenia. 2015.
Liu C., Saffen D., Schulze T.G., Burmeister M., Sham P.C., Yao Y.G., Kuo P.H., Chen C., An Y., Dai J., Yue W., Li M., Xue H., Su B., Chen L., Shi Y., Qiao M., Liu T., Xia K. and Chan R.C.K., Psychiatric genetics in China: achievements and challenges, Molecular Psychiatry. 2016, 21: 4-9.
Liu W., WONG K.L., He Q.M., Wong H.M.E., Tang S.M., ZHANG R., So M.T., Wong K.K.Y., Nicholls J.M., Cherny S.S., Sham P.C., Tam P.K.H., Garcia-Barcelo M.M. and Xia H.M., Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism, BMC Medical Genetics. 2015, 16(1): 49.
PORSCH R.M., Middeldorp C.M., Cherny S.S., Krapohl E., van Beijsterveldt C.E.M., Luokola A., Korhonen T., Pulkkinen L., Corley R., Rhee S., Kaprio J., Rose R.R., Hewitt J.K., Sham P.C., Plomin R., Boomsma D.I. and Barteis M., Longitudinal heritability of childhood aggression, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2016, n/a-n/a.
Tang S.M., Zhang H., Cheung Y.Y., Xu M., Ho J.C.Y., Zhou W., Cherny S.S., Zhang Y., Holmen O., Au K.W., Yu H., Xu L., Jia J., PORSCH R.M., Sun L., Xu W., Zheng H., Wong L.Y., Mu Y., Dou J., Fong H.Y., Wang S., Hong X., Dong L., Liao Y., Wang J., Lam S.M.L., Su X., Yan H., Yang M.L., Chen J., Siu D.C.W., Xie G., Woo Y.C., Wu Y., Tan K.C.B., Hveem K., Cheung B.M.Y., Zöllner S., Xu A., Eugene Chen Y., Jiamg C.Q., Jiang Y., Lam T.H., Ganesh S.K., Huo Y., Sham P.C., Lam K.S.L., Willer C.J., Tse H.F. and Gao W., Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese, Nature Communications. 2015, 6: 10206.
Tang S.M., So M.T., Cherny S.S., Sham P.C., Tam P.K.H. and Garcia-Barcelo M.M., Rare variants in sporadic Hirshcsprung disease patients (Abstract and Poster presentation), 65th Annual Meeting of American Society of Human Genetics, Baltimore, U.S.A. 6-10 October 2015.
Tang S.M., Gui H., Cherny S.S., Sham P.C., Tam P.K.H. and Kim J.H., Trans-ethnic meta-analysis of Hirschsprung disease (Abstract and Poster Presentation), European Human Genetics Conference (ESHG) 2016, Barcelona, Spain, 21-24 May 2016.
Wang B., Ji T., Zhou X., Wang J., Wang X., Wang J.M., Zhu D., Zhang X.J., Sham P.C., Zhang X.G., Ma X. and Jiang Y., CNV analysis in Chinese children of mental retardation highlights a sex differentiation in parental contribution to de novo and inherited mutational burdens, Scientific Reports. Nature Publishing Group, 2016.
Wang Q., Li M., Yang Z., Hu X., Wu H.M., Ni P., Ren H., Deng W., Li M., Ma X., Guo W., Zhao L., Wang Y., Xiang B., Lei W., Sham P.C. and Li T., Increased co-expression of genes harboring the damaging de novo mutations in Chinese schizophrenic patients during prenatal development, Scientific Reports. 2015, 5: 18209.
Wang Q., Cheng W., Li M., Ren H., Hu X., Deng W., Ma X., Zhao L., Wang Y., Xiang B., Wu H.M., Sham P.C., Feng J. and Li T., The CHRM3 gene is implicated in abnormal thalamo-orbital frontal cortex functional connectivity in first-episode treatment-naive patients with schizophrenia, Psychological Medicine. 2016, 46: 1523-1534.
XIONG C., LI Y., RAI F.M., SANDELL L., ZHANG Y., Song Y., Cheah K.S.E., Sham P.C. and Chan D., Genetic contribution to degeneration and repair potentials of the intervertebral disc in mice, 20th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine of The University of Hong Kong. 2015.
ZHANG J., ZHANG L., ZHANG Y., Yang J., GUO M., Sun L., Pan H.F., Hirankarn N., Ying D., Zeng S., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W.G., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong W.S.R., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Cui Y., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations , Arthritis & Rheumatology. 2015, 67(11): 2966-77.


Researcher : So HC

List of Research Outputs

Chan K.W., Ching Y.N.E., Lam S.C., So H.C., Hui C.L.M., Lee H.M.E., Chang W.C. and Chen E.Y.H., Newspaper coverage of mental illness in Hong Kong between 2002 and 2012: impact of introduction of a new Chinese name of psychosis, Early Intervention in Psychiatry. 2015, n/a-n/a.
Lee H.M.E., So H.C. and Chen E.Y.H., Admission Rates and Psychiatric Beds in Hong Kong, 1999–2014: A Population-Based Study, Psychiatric Services. 2016, 67: 579-579.


Researcher : TAM WYW

List of Research Outputs

Chan K.W., TAM W.Y.W., LEE K.W., Hui C.L.M., Chang W.C., Lee H.M.E. and Chen E.Y.H., A population study of public stigma about psychosis and its contributing factors among Chinese population in Hong Kong, International Journal of Social Psychiatry. 2015, 62(3): 205-213.


Researcher : Tang SM

Project Title:A transethnic meta-analysis of genome-wide association studies for Hirschsprung disease
Investigator(s):Tang SM, Tam PKH, Sham PC, Garcia-Barcelo MM, Cherny SS
Department:Psychiatry
Source(s) of Funding:Health and Medical Research Fund - Mini Grant
Start Date:01/2014
Completion Date:07/2016


Project Title:Copy number variation in syndromic Hirschsprung disease patients
Investigator(s):Tang SM, Garcia-Barcelo MM, Cherny SS, Sham PC, Tam PKH
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:06/2014
Completion Date:11/2015


Project Title:European Society of Human Genetics; Trans-ethnic meta-analysis of Hirschsprung disease
Investigator(s):Tang SM
Department:Surgery
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:05/2016
Completion Date:05/2016


Project Title:Deciphering the co-morbidity between Hirschsprung disease and Down syndrome
Investigator(s):Tang SM, Garcia-Barcelo MM, Tam PKH
Department:Surgery
Source(s) of Funding:Seed Fund for Basic Research
Start Date:06/2016


List of Research Outputs

Liu W., WONG K.L., He Q.M., Wong H.M.E., Tang S.M., ZHANG R., So M.T., Wong K.K.Y., Nicholls J.M., Cherny S.S., Sham P.C., Tam P.K.H., Garcia-Barcelo M.M. and Xia H.M., Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism, BMC Medical Genetics. 2015, 16(1): 49.
Tang S.M., Zhang H., Cheung Y.Y., Xu M., Ho J.C.Y., Zhou W., Cherny S.S., Zhang Y., Holmen O., Au K.W., Yu H., Xu L., Jia J., PORSCH R.M., Sun L., Xu W., Zheng H., Wong L.Y., Mu Y., Dou J., Fong H.Y., Wang S., Hong X., Dong L., Liao Y., Wang J., Lam S.M.L., Su X., Yan H., Yang M.L., Chen J., Siu D.C.W., Xie G., Woo Y.C., Wu Y., Tan K.C.B., Hveem K., Cheung B.M.Y., Zöllner S., Xu A., Eugene Chen Y., Jiamg C.Q., Jiang Y., Lam T.H., Ganesh S.K., Huo Y., Sham P.C., Lam K.S.L., Willer C.J., Tse H.F. and Gao W., Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese, Nature Communications. 2015, 6: 10206.


Researcher : Vinas Guasch N

List of Research Outputs

Mueller-Gathercole V.C.M., Thomas E.M. and Vinas Guasch N., Teasing apart factors influencing executive function performance in bilinguals and monolinguals at different ages, In: Irina A. Sekerina Lauren Spradlin, Linguistic Approaches To Bilingualism. 2016.


Researcher : WONG KL

List of Research Outputs

Cherny S.S., WONG K.L., Sham P.C., Baum L.W. and Kwan P., Exome sequencing of mesial temporal lobe epilepsy with hippocampal sclerosis in parent-offspring trios, Annual meeting of the Behavior Genetics Association. 2015.
Chiu Y.T., Wong K.L., Choi S.W., Sze M.F., Ho D.W.H., Chan L.K., Lee M.F., Man K., Cherny S.S., Yang W., Wong C.M., Sham P.C. and Ng I.O.L., Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma, Journal of Hepatology. 2016, 64(6): 1256-64.
Liu W., WONG K.L., He Q.M., Wong H.M.E., Tang S.M., ZHANG R., So M.T., Wong K.K.Y., Nicholls J.M., Cherny S.S., Sham P.C., Tam P.K.H., Garcia-Barcelo M.M. and Xia H.M., Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism, BMC Medical Genetics. 2015, 16(1): 49.


Researcher : Wong HME

List of Research Outputs

Liu W., WONG K.L., He Q.M., Wong H.M.E., Tang S.M., ZHANG R., So M.T., Wong K.K.Y., Nicholls J.M., Cherny S.S., Sham P.C., Tam P.K.H., Garcia-Barcelo M.M. and Xia H.M., Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism, BMC Medical Genetics. 2015, 16(1): 49.


Researcher : Wong JGWS

Project Title:What makes a good clinical teacher in the new medical curriculum? A focus group study on student perception
Investigator(s):Wong JGWS, Lam TP, Mak-Lieh F
Department:Psychiatry
Source(s) of Funding:Other Funding Scheme
Start Date:01/2002


Project Title:A follow-up study on the severity of psychological sequelae in SARS patients
Investigator(s):Wong JGWS, Sham PC, Wong PC, McAlonan GM, Chu CM, Lee AM, Lee WHP, Tsang KWT, Chua SE
Department:Psychiatry
Source(s) of Funding:Small Project Funding
Start Date:11/2004


List of Research Outputs

Chau H.S., Chong W.S., Wong J.G.W.S., Hung B.K.G., Lui S.Y., Chan K.W., Chang W.C., Hui C.L.M., Lee H.M.E., McGorry P.D., Jones P.B. and Chen E.Y.H., Early intervention for incipient insanity: early notions from the 19th century English literature., Early Intervention in Psychiatry. 2016, 2016 Jun 7. doi: 10.1111/eip.12355. [Epub ahead of print].


Researcher : Wong KL

List of Research Outputs

Cherny S.S., WONG K.L., Sham P.C., Baum L.W. and Kwan P., Exome sequencing of mesial temporal lobe epilepsy with hippocampal sclerosis in parent-offspring trios, Annual meeting of the Behavior Genetics Association. 2015.
Chiu Y.T., Wong K.L., Choi S.W., Sze M.F., Ho D.W.H., Chan L.K., Lee M.F., Man K., Cherny S.S., Yang W., Wong C.M., Sham P.C. and Ng I.O.L., Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma, Journal of Hepatology. 2016, 64(6): 1256-64.
Liu W., WONG K.L., He Q.M., Wong H.M.E., Tang S.M., ZHANG R., So M.T., Wong K.K.Y., Nicholls J.M., Cherny S.S., Sham P.C., Tam P.K.H., Garcia-Barcelo M.M. and Xia H.M., Chinese family with diffuse oesophageal leiomyomatosis: a new COL4A5/COL4A6 deletion and a case of gonosomal mosaicism, BMC Medical Genetics. 2015, 16(1): 49.


Researcher : Wong MMC

Project Title:Enrichment of collections in the library of the S.K. Yee Mental Health Resources and Rehabilitation Centre
Investigator(s):Wong MMC, Mak KY, Mak-Lieh F, Yau FYE
Department:Psychiatry
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2001




Researcher : Wu HM

List of Research Outputs

Wang Q., Li M., Yang Z., Hu X., Wu H.M., Ni P., Ren H., Deng W., Li M., Ma X., Guo W., Zhao L., Wang Y., Xiang B., Lei W., Sham P.C. and Li T., Increased co-expression of genes harboring the damaging de novo mutations in Chinese schizophrenic patients during prenatal development, Scientific Reports. 2015, 5: 18209.
Wang Q., Cheng W., Li M., Ren H., Hu X., Deng W., Ma X., Zhao L., Wang Y., Xiang B., Wu H.M., Sham P.C., Feng J. and Li T., The CHRM3 gene is implicated in abnormal thalamo-orbital frontal cortex functional connectivity in first-episode treatment-naive patients with schizophrenia, Psychological Medicine. 2016, 46: 1523-1534.


Researcher : Xu J

List of Research Outputs

Hui C.L.M., Lee H.M.E., Chang W.C., Chan K.W., Lin J., Xu J. and Chen E.Y.H., Delusional disorder and schizophrenia: a comparison of the neurocognitive and clinical characteristics in first-episode patients, Psychological Medicine. 2015.


Researcher : YUNG KP

List of Research Outputs

Chan M.S., Chung K.F., YUNG K.P. and Yeung W.F., Sleep in schizophrenia: A systematic review and meta-analysis of polysomnographic findings in case-control studies, Sleep Medicine Reviews. 2016.
LAM T.H., Chung K.F., Yeung W.F., Yu Y.M.B., YUNG K.P. and NG H.Y., Hypnotherapy for insomnia: A systematic review and meta-analysis of randomized controlled trials, Complementary Therapies in Medicine. 2015, 23: 719-732.
Yeung W.F., Chung K.F., Zhang N.L.W., Zhang S.P., YUNG K.P., Chen P.X. and HO Y.Y.F., Identification of Chinese medicine syndromes in persistent insomnia associated with major depressive disorder: a latent tree analysis, Chinese Medicine. 2016, 11.


Researcher : Yang Z

List of Research Outputs

Wang Q., Li M., Yang Z., Hu X., Wu H.M., Ni P., Ren H., Deng W., Li M., Ma X., Guo W., Zhao L., Wang Y., Xiang B., Lei W., Sham P.C. and Li T., Increased co-expression of genes harboring the damaging de novo mutations in Chinese schizophrenic patients during prenatal development, Scientific Reports. 2015, 5: 18209.


Researcher : Yeung WF

Project Title:A Systemic Review on the Effectiveness of Chinese Herbal Medicine for Depression
Investigator(s):Yeung WF, Chung KF
Department:Psychiatry
Source(s) of Funding:Hospital Authority - General Award
Start Date:02/2013


Project Title:Validity and Reliability of the Chinese Version of Uterine Fibroid Symptom and Quality of Life (UFS-QOL) Questionnaire in Hong Kong Chinese Population
Investigator(s):Yeung WF, Meng W, Chen H, Lao L, Lin WL, Chung KF
Department:School of Chinese Medicine
Source(s) of Funding:Small Project Funding
Start Date:06/2015
Completion Date:05/2016


Project Title:Electroacupuncture for tapering off long-term benzodiazepine use: a randomized controlled trial
Investigator(s):Yeung WF, Chung KF, Zhang Z, Chan WC, Ho LM, Lao L
Department:School of Chinese Medicine
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:07/2015
Completion Date:06/2016


List of Research Outputs

LAM T.H., Chung K.F., Yeung W.F., Yu Y.M.B., YUNG K.P. and NG H.Y., Hypnotherapy for insomnia: A systematic review and meta-analysis of randomized controlled trials, Complementary Therapies in Medicine. 2015, 23: 719-732.


Researcher : Yu YMB

List of Research Outputs

Chung K.F., Yu Y.M.B. and Yeung W.F., Correlates of residual fatigue in patients with major depressive disorder: The role of psychotropic medication, Journal of Affective Disorders. 2015, 186: 192-197.
LAM T.H., Chung K.F., Yeung W.F., Yu Y.M.B., YUNG K.P. and NG H.Y., Hypnotherapy for insomnia: A systematic review and meta-analysis of randomized controlled trials, Complementary Therapies in Medicine. 2015, 23: 719-732.


Researcher : Zhang MQ

List of Research Outputs

Cheah K.S.E., Au Y.K., Niu B., Chan D. and Zhang M.Q., SPINE-GEL: a global gene expression library for the developing nucleus pulposus., Spine Week, Singapore, May 16-20, 2016.


Researcher : Zhou X

List of Research Outputs

Chen H., Zhou X., Wang J., Wang X., Liu L., Wu S., Li T., Chen S., Yang J., Sham P.C., Zhu G., Zhang X. and Wang B., Exome Sequencing and Gene Prioritization Correct Misdiagnosis in a Chinese Kindred with Familial Amyloid Polyneuropathy, Scientific Reports. Nature Publishing Group, 2016.
Wang B., Ji T., Zhou X., Wang J., Wang X., Wang J.M., Zhu D., Zhang X.J., Sham P.C., Zhang X.G., Ma X. and Jiang Y., CNV analysis in Chinese children of mental retardation highlights a sex differentiation in parental contribution to de novo and inherited mutational burdens, Scientific Reports. Nature Publishing Group, 2016.


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