DEPT OF OBSTETRICS & GYNAECOLOGY



Researcher : CHEN K

List of Research Outputs

CHEN K., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness via targeting GRB7, AACR Annual Meeting 2017. Walter E. Washington Convention Center W, American Association of Cancer Research.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.


Researcher : CHEN R

List of Research Outputs

CHEN R., Ngan H.Y.S. and Chan D.W., The AMPK/TAK1/NF-kB signaling axis is indispensable for modulating ovarian cancer cell metabolism and peritoneal metastases, The 21st Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, 1-2 Dec, 2016.
CHEN R., Ngan H.Y.S. and Chan D.W., The roles of AMPK and TAK1/NF-kB signaling cascade in governing cancer cell aggressiveness in omental microenvironemnt, the 24th Biennial European Association for Cancer Research (EACR) Congress, 9-12 July, 2016, Manchester, UK. 2016.


Researcher : Chai J

Project Title:10th RCOG International Scientific Congress A randomized clinical trial comparing the sublingual and buccal routes of administration of misoprostol after mifepristone for medical abortions of up to 63 days gestation
Investigator(s):Chai J
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2012


List of Research Outputs

Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.


Researcher : Chan DW

Project Title:Functional significance of TAK1-mediated NFkB signaling in omental metastasis of ovarian cancer
Investigator(s):Chan DW, Yam JWP, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013
Completion Date:10/2016


Project Title:The mechanism and significance of ovarian cancer cells in modulating AMPK and TNFkB signaling cascade in omental metastasis
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2015


Project Title:Identification of BCL2A1 as a novel stress-inducible factor in metastatic progression of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2015


Project Title:The functional role of Hsa-miR-141 in metastatic progression of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2015


Project Title:Investigation the impact of lipid metabolism in peritoneal metastases of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016


Project Title:Functional characterization of the MAP30 protein from bitter melon (Momordica chrantia) in combating ovarian cancer oncogenesis and chemoresistance
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2016


Project Title:Functional characterization of BCL2A1 in peritoneal metastases of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research for Resubmission of GRF/ECS Proposals
Start Date:07/2016
Completion Date:11/2016


Project Title:Cancer and Metabolism; The significance of lipid metabolism in peritoneal metastases of ovarian cancer
Investigator(s):Chan DW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2016
Completion Date:09/2016


List of Research Outputs

CHEN K., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness via targeting GRB7, AACR Annual Meeting 2017. Walter E. Washington Convention Center W, American Association of Cancer Research.
CHEN R., Ngan H.Y.S. and Chan D.W., The AMPK/TAK1/NF-kB signaling axis is indispensable for modulating ovarian cancer cell metabolism and peritoneal metastases, The 21st Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, 1-2 Dec, 2016.
CHEN R., Ngan H.Y.S. and Chan D.W., The roles of AMPK and TAK1/NF-kB signaling cascade in governing cancer cell aggressiveness in omental microenvironemnt, the 24th Biennial European Association for Cancer Research (EACR) Congress, 9-12 July, 2016, Manchester, UK. 2016.
Chan D.W., Yung M.H., Hardie D.G. and Ngan H.Y.S., AMP-activated protein kinase gamma-2 (AMPK-g2) subunit modulates AMPK activities to ensure ovarian cancer progression, AMPK 2016: NEW MECHANISMS and PHYSIOLOGY, November 11-16, 2016, Xiamen, China. 2016.
Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-b/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.
Chan D.W., Editorial Board Member, Cancer Medicine. USA, John Wiley & Sons, 2016.
Chan D.W., Editorial Board Member, Frontiers of Pharmacology of Anti-Cancer Drugs. Frontiers, 2016.
Chan D.W., Editorial Board Member, Gynecology & Obstetrics . OMICS Publishing Group, 2017.
Chan D.W., Editorial Board Member, Journal of Cancer Metastasis and Treatment. 2016.
Chan D.W., Editorial Board Member, PLoS One. San Francisco, CA, USA, plos.org, 2016.
Chan D.W., Senior Editor, In: Robert Peng, American Journal of Clinical Cancer Research. Ivy Union Publishing LLC, 2016.
Chan D.W., MAK S.L. and Ngan H.Y.S., The significance of lipid metabolism in peritoneal metastases of ovarian cancer, Cold Spring Harbour Asia: Cancer & Metabolism. Suzhou Dushu Lake Conference Center, Suzhou, PR China, 19 to 23rd, Sept., 2016.. 2016.
Chan D.W., The significance of lipid metabolism in peritoneal metastases of ovarian cancer, The 4th Meeting of the International Ovarian Cancer Consortium. Februrary 23- 25 at Seoul National University Hospital, Seoul, Republic of Korea. 2017.
LIANG R., Yung M.H., Ngan H.Y.S. and Chan D.W., BCL2A1 plays a biphasic role in ovarian cancer progression: promoting cell survival and inhibiting cell proliferation, Cold Spring Harbour Asia: Cancer & Metabolism. Suzhou Dushu Lake Conference Center, Suzhou, PR China, 19 to 23rd, Sept., 2016.. 2016.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.
YUNG M.H., ROSS F.A., HARDIE D.G., ZHAN J.B., Ngan H.Y.S. and Chan D.W., Bitter melon (Momordica charantia) extract functions as a natural AMPK activator and synergistically enhances cisplatin cytotoxicity in ovarian cancer cells, Integrat Cancer Ther. 2016, 15(3): 376-89.
Yan F., Ying L., Li X., Qiao B., Meng Q., Yu L., Yuan X., Ren S.T., Chan D.W., Shi L., Ni P., Wang X., Xu D. and Hu Y., Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer, Oncotarget. USA, Impact Journals, 2017.
Yung M.H., Ngan H.Y.S., Hardie D.G. and Chan D.W., Functional characterization of MAP30 protein from bitter melon (Momordica charantia) in combating ovarian cancer oncogenesis and chemoresistance, AMPK 2016: NEW MECHANISMS AND PHYSIOLOGY (The 9thInternational Symposium on AMP-activated Protein Kinase) Nov. 11-16, 2016, Xiamen, China. 2016.
Yung M.H., Ngan H.Y.S. and Chan D.W., Identification of MAP30 as a natural AMPK activator in targeting the tumorigenicity and chemoresistance of ovarian cancer cells, CSH Asia Conference on Cancer & Metabolism. 2016.


Researcher : Chan KKL

Project Title:Relationship between placental ratio and placental function
Investigator(s):Chan KKL, Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding for New Staff
Start Date:01/2003


Project Title:The effect of fulvestrant in epithelial ovarian cancer with differential estrogen receptor status in mice
Investigator(s):Chan KKL, Liu S, Tam KF, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2008


Project Title:Sixth International Symposium on Hormonal Oncogenesis USE OF HIGHLY SELECTIVE ESTROGEN RECEPTOR MODULATORS IN OVARIAN CANCER
Investigator(s):Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2010


Project Title:Role of pyruvate dehydrogenase kinase 1 (PDK1) in tumorigenesis and metastasis of ovarian cancer
Investigator(s):Chan KKL, Ngan HYS, Cheung ANY, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2014
Completion Date:10/2016


Project Title:Characterization of PFKFB3 in ovarian cancer
Investigator(s):Chan KKL, Ngan HYS, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2015
Completion Date:02/2017


Project Title:Hexokinase 2 (HK2) in ovarian cancer tumorigenesis and metastasis
Investigator(s):Chan KKL, Ngan HYS, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2016


Project Title:Roles of Soy Isoflavones on metastasis and CSCs regulation in ovarian cancer
Investigator(s):Chan KKL, Ngan HYS, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2017


List of Research Outputs

Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-b/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.
Chan K.K.L., Adjuvant treatment in node negative early cervical cancer, AOGIN 2016 Singapore. 2016.
Chan K.K.L., The new HKCOG guidelines on cervical cancer prevention. HKSCCP 15th Anniversary Symposium 10 Dec 2016, 2016.
Chan K.K.L.,  Robotic pelvic and para-aortic lymphadenectomy. The 2nd Asian Congress of Robotic Surgery. Gyeongju, Korea 25-26 Nov 2016, 2016.
JIANG Y., Siu K.Y., WANG J., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., Hexokinase II (HK2) regulates stemness of ovarian cancer cells, AACR Annual Meeting 2017.
Janda M., Gebski V., Davies L.C., Forder P., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K., Chan K.K.L., Wrede C.D., Pather S., Simcock B., Farrell R., Robertson G., Walker G., Armfield H.R., Graves N., McCartney A.J. and Obermair A., Effect of Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy on Disease-Free Survival Among Women With Stage I Endometrial Cancer: A Randomized Clinical Trial, JAMA. 2017, 317(12): 1224-1233.
Liu S., Chu K.H., Wei N., Lau S.K., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Circulating micro-RNAs as biomarkers for detection of cervical cancer, International Papillomavirus Conference. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.
Ngu S.F., Wei N., Kwan T.T., Chu M.Y.M., Tse K.Y., Chan K.K.L. and Ngan H.Y.S., Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial., J Psychosom Obstet Gynaecol. 2017.
WANG J., Siu K.Y., JIANG Y., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., PFKP and PFKFB3 modulate cancer metabolic switch and chemoresistance to cisplatin in ovarian cancer, AACR Annual Meeting 2017.
ZHANG N., Fielding R., Soong S.I., Chan K.K.L., Lee C., Ng A., Sze W.K., Tsang W.H.J., Lee V.H.F. and Lam W.W.T., Psychometric assessment of the Chinese version of the brief illness perception questionnaire in breast cancer survivors, PLoS One. 2017, 12(3): e0174093.


Researcher : Chan MKD

Project Title:A randomized double-blind controlled trial of use of progesterone in women with threatened miscarriage in the first trimester
Investigator(s):Chan MKD, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:12/2015


List of Research Outputs

Chan M.K.D., Cheung K.W., Yung S.F., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., A randomized double-blind controlled trial of the use of dydrogesterone in women with threatened miscarriage in the first trimester: study protocol for a randomized controlled trial, Trials. 2016, 17.


Researcher : Chan RWS

List of Research Outputs

Chan R.W.S., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Co-culture with macrophages enhances the clonogenic and invasion activity of endometriotic stromal cells, Cell Proliferation. John Wiley & Sons Ltd, 2017, 50: 1-9.
Cheng H.C., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., The role of myometrium in maintaining the endometrial mesenchymal-like stem cells through secretion of matrix metalloproteinase 3, Hong Kong Society of Endocrinology Metabolism & Reproduction, Hong Kong, 20th Nov 2016. Abstract P-03: p 17.
XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Characterization of Endometrial Mesenchymal-like Stem Cells Activity in Different Endometrial Layers and During the Menstrual Cycle, 49th Society for the Study of Reproduction. 2016.
Xu S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle, Experimental Cell Research. Elsevier Inc, 2017, 350(1): 184-189.


Researcher : Chan YK

Project Title:Validating and examining SNPs identified from genome-wide scanning for disease susceptibility to HBV-related liver cancer in Chinese population
Investigator(s):Chan YK, Ng IOL, Wong CM
Department:Pathology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2010


List of Research Outputs

Chu W.Y., LEUNG K.C., Mak A.S.L., Chiu T.A., MAK C.C.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong V.C.N., Lee S.L., Marshall C., Scherer S., Kan S.Y.A. and Chung B.H.Y., Use of clinical chromosomal microarray in Hong Kong Chinese patients with autism spectrum disorder - Implication of a copy number variation involving DPP10, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Chung B.H.Y., Mak S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Chan Y.K., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Fung C.W. and Lee S.L., Use of chromosomal microarray in Hong Kong patients with autism spectrum disorder - implication of a copy number variation involving DPP10, ASHG 2016, Vancouver, Canada, 18-22 October 2016.
LEUNG K.C., Ying D., MAK C.C.Y., Chen X.Y., Xu W., YEUNG K.S., Wong W.L., Chu W.Y., Mok T.K.G., Chau S.K.C., McLuskey J., Ong W.P.T., Leong H.Y., Chan Y.K., Yang W., Chen J.H., Li A.M., Sham P.C., Lau Y.L., Chung B.H.Y. and Lee S.L., CFTR founder mutation causes protein trafficking defects in Chinese patients with cystic fibrosis , Molecular Genetics & Genomic Medicine. 2016.
LEUNG K.C., Ying D., MAK C.C.Y., Chen X.Y., Xu W., YEUNG K.S., Chu W.Y., Mok T.K.G., Chau S.K.C., McLuskey J., Ong W.P.T., Leong H.Y., Chan Y.K., Yang W., Chen J.H., Li A.M., Lau Y.L., Lee S.L. and Chung B.H.Y., Identification of a CFTR founder mutations, c.3068T>G:p.I1023R, which causes protein trafficking defects in Chinese patients with cystic fibrosis, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
LEUNG K.C., Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K., Ip J.K.J., Yang W., Lau Y.L. and Chung B.H.Y., Identification of a novel homozygous missense mutation in ABR causing cerebellar hypoplasia with early lethality, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Lee H.L.H., Mak A.S.L., Kou K.O.T., Poon C.F., Wong W.S., Chiu K.H., Au H.H.L., Chan Y.K., Kan S.Y.A., Tang M.H.Y. and Leung K.Y., An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations, Hemoglobin. 2016, 40(6): 431-434.
MAK C.C.Y., Chow P.C., Liu A.P.Y., Chan Y.K., Chu W.Y., Mok T.K.G., LEUNG K.C., YEUNG K.S., Chau A.K.T., Lowther C., Scherer S.W., Marshall C.R., Bassett A.S. and Chung B.H.Y., De novo large rare copy-number variations contribute to conotruncal heart disease in Chinese patients, npj Genomic Medicine. 2016, 1: 16033.


Researcher : Chen CH

List of Research Outputs

Chen C.H., Lee C.Y.L., Fong S.W., Wong C.C.Y., Ng E.H.Y. and Yeung W.S.B., Hyperglycemia impedes definitive endoderm differentiation of human embryonic stem cells by modulating histone methylation patterns, Cell and Tissue Research. 2017, 2017 Jun;368(3):563-578.


Researcher : Cheng MCM

List of Research Outputs

Yung S.F.S., Cheng M.C.M., Ma W.S.P. and Ho P.C., Candida glabrata chorioamnionitis and fungaemia complicating pregnancy following intrauterine insemination: Case report and review of the literature, 25th Asian & Oceanic Congress of Obstetrics and Gynaecology (AOCOG) 2017 (The Journal of Obstetrics and Gynaecology Research). Wiley, 2017, 43, Issue Supplement S1: 140.


Researcher : Cheung KW

Project Title:A multi-center prospective study on the evaluation of paternal, maternal and obstetric factors leading to the hepatitis B immunization failure in Hong Kong
Investigator(s):Cheung KW, Seto TYM, Kan SYA, Ng EHY, Lau WL, Wong RMS, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


List of Research Outputs

Chan M.K.D., Cheung K.W., Yung S.F., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., A randomized double-blind controlled trial of the use of dydrogesterone in women with threatened miscarriage in the first trimester: study protocol for a randomized controlled trial, Trials. 2016, 17.
Cheung K.W. and Cheung V.Y.T., Pyoadenomyosis: A Rare Complication of Adenomyosis, Journal of Obstetrics and Gynaecology Canada. 2016, 38: 789.


Researcher : Cheung SYC

List of Research Outputs

Cheung S.Y.C., Menstrual disorders in adolescents, Hong Kong Medical Diary 2016. 2016, 21(10): 22-26.


Researcher : Cheung TM

List of Research Outputs

Li R.H.W., Cheung T.M., Yeung W.S.B. and Ng E.H.Y., Relative importance of the different components of the Bologna criteria for predicting poor ovarian response in assisted reproduction., 11th European Congress on Menopause and Andropause. 2017.


Researcher : Cheung VYT

List of Research Outputs

Chan D.M.K. and Cheung V.Y.T., Urinothorax as an early sign of urinary tract injury following total laparoscopic hysterectomy, International Journal of Gynecology & Obstetrics. 2016, 134: 102-103.
Cheung K.W. and Cheung V.Y.T., Pyoadenomyosis: A Rare Complication of Adenomyosis, Journal of Obstetrics and Gynaecology Canada. 2016, 38: 789.
Cheung V.Y.T., Current status of high-intensity focused ultrasound for the management of uterine adenomyosis, Ultrasonography. 2017, 36: 95-102.
Cheung V.Y.T., Dystrophic Calcification in the Pelvis, Journal of Minimally Invasive Gynecology. 2016, 23: 1023.
Cheung V.Y.T., Efficacy and safety of ultrasound-guided high-intensity focused ultrasound in the treatment of uterine fibroids: a prospective cohort study, 3rd Congress of the Society of Endometriosis and Uterine Disorders, Singapore, April 2017.. 2017.
Cheung V.Y.T., Focused ultrasound therapy, 25th Asian and Oceanic Congress of Obstetrics and Gynaecology, Hong Kong, June 2017. 2017.
Cheung V.Y.T., Laparoscopic myomectomy and risk of uterine rupture, 3rd Congress of the Society of Endometriosis and Uterine Disorders, Singapore, April 2017. 2017.
Cheung V.Y.T., Significance of Uterine Cavity Fibroids and Polyps in Reproductive Medicine., SRL Reprod Med Gynecol. 2017, 3: 4-9.
Cheung V.Y.T., Uterine-sparing interventions for adenomyosis, HKCOG Postgraduate Seminar. 2016.
Cheung V.Y.T. and Tse K.Y., Vulval Hemangioma, Journal of Obstetrics and Gynaecology Canada. 2017.
Ko J.K. and Cheung V.Y.T., Management and outcome of sonographically diagnosed uterine enhanced myometrial vascularity / arteriovenous malformations following early pregnancy events: a single center experience., Medical Ultrasonography. 2016, 403-4.
Lui M.W.E. and Cheung V.Y.T., Three-dimensional versus two-dimensional laparoscopy for ovarian cystectomies: a prospective randomized study, 25th Asian and Oceanic Congress of Obstetrics and Gynaecology. 2017.
Shum J.W.H., Choy N.K.B., Chan J.C.H., Ho W.L., Jiang B.Y., Choi W.K., Cheung V.Y.T. and Lai J.S.M., Visual Field Compromised In Patients Suffering From Severe Menorrhagia, J Ophthalmol Open Access, 2017. 2017.
Tse K.Y., Cheung V.Y.T., Lam C.W., Lee E.Y.P., Ngan H.Y.S. and Khong P.L., Successful Treatment of a Pararenal Pregnancy Using High-Dose Methotrexate Regimen A Case Report, Journal of Reproductive Medicine. United States, Journal of Reproductive Medicine, Inc., 2016, 61 issue 11-12: 592-594.
Wai K.O.J. and Cheung V.Y.T., The Uterine-shaped Intrauterine Device, Journal of Obstetrics and Gynaecology Canada. 2017.


Researcher : Chiu CN

Project Title:The roles of protein disulfide isomerase family A, member 3 (ERp57) and surface thiol/disulfide exchange in spermatozoa-zona pellucida binding and their association with fertilization in vitro.
Investigator(s):Chiu CN, Pang TKR, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:The role of galectin-3 in spermatozoa-zona pellucida binding and its association with fertilization in vitro
Investigator(s):Chiu CN, Yeung WSB, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Control of human extravillous cytotrophoblast functions by adrenomedullin and its association with preeclampsia
Investigator(s):Chiu CN, Yeung WSB, Kan SYA
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2015


Project Title:The role of glycodelin-A on the vascular remodeling function of decidual natural killer cells during early pregnancy and its association with preeclampsia
Investigator(s):Chiu CN, Wong AST, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2015


List of Research Outputs

Lee C.L., Yeung W.S.B. and Chiu C.N., Soluble Human Leukocyte Antigen G5 Polarizes Decidual Macrophage Differentiation from Monocyte to Promotes Fetomaternal Tolerance and Placental Development, Hong Kong Society of Endocrinology, Metabolism and Reproduction - Annual Scientific Meeting. 2016.
Lee C.L., Yeung W.S.B. and Chiu C.N., Soluble Human Leukocyte Antigen G5 Polarizes Decidual Macrophage Differentiation from Monocyte to Promotes Fetomaternal Tolerance and Placental Development, Hong Kong Society of Endocrinology, Metabolism and Reproduction - Annual Scientific Meeting. 20 Nov 2016, HK. 2016.
Wong C.W., Lam K.W., Lee C.L., Yeung W.S.B., Zhao W.E., Ho P.C., Oue J.P. and Chiu C.N., The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa-zona pellucida binding, Human Reproduction. 2017, 32: 733-742.


Researcher : Chu KH

List of Research Outputs

Liu S., Chu K.H., Wei N., Lau S.K., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Circulating micro-RNAs as biomarkers for detection of cervical cancer, International Papillomavirus Conference. 2017.


Researcher : Chu MYM

List of Research Outputs

Ngu S.F., Wei N., Kwan T.T., Chu M.Y.M., Tse K.Y., Chan K.K.L. and Ngan H.Y.S., Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial., J Psychosom Obstet Gynaecol. 2017.
Ngu S.F., Chu M.Y.M., Ip P.C.P. and Ngan H.Y.S., Vulvar Hidradenitis Suppurativa: Is the Mass Malignant? , J Obstet Gynaecol Can.. 2017.


Researcher : FAN H

List of Research Outputs

FAN H., Yeung W.S.B. and Lee C.K.F., Bisphenol aA analogues: effect on gene activation and spheroid attachment in endometrial epithelial iIshikawa cells, 33th Annual Scientific Meeting of Hong Kong society of Endocrinology, Metabolism and Reproduction. Hong Kong, China. 2016.
FAN H., Yeung W.S.B. and Lee C.K.F., Effect of bisphenol aA analogues on gene regulation and spheroid attachment in endometrial epithelial iIshikawa cells, 21st Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong. Hong Kong, China. 2016.
FAN H., Wong C.K.C., Yeung W.S.B. and Lee C.K.F., Molecular and functional approach to delineate the effect of bisphenol analogues on the receptivity of human endometrial epithelial cells, 30th Anniversary Celebration of the HKU-QMH Assisted Reproduction Programme. Shenzhen, China. 2016.


Researcher : Fong SW

List of Research Outputs

Chen C.H., Lee C.Y.L., Fong S.W., Wong C.C.Y., Ng E.H.Y. and Yeung W.S.B., Hyperglycemia impedes definitive endoderm differentiation of human embryonic stem cells by modulating histone methylation patterns, Cell and Tissue Research. 2017, 2017 Jun;368(3):563-578.


Researcher : Ho PC

List of Research Outputs

Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., A randomized double-blinded controlled trial of hCG as luteal phase support in natural cycle frozen embryo transfer, Human Reproduction. 2017, 32: 1130-1137.
Li R.H.W., Lam K.S.L., Tam S., Shek A.C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum Vitamin D Concentration Is Independently Associated With Anti-mullerian Hormone Level And Obesity Measures In Hong Kong Chinese Women With Polycystic Ovary Syndrome, 17th International Congress of Endocrinology cum 15th Annual Meeting of Chinese Society of Endocrinology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum Vitamin D concentration is independently associated with anti-Mullerian hormone level and obesity measures in Hong Kong Chinese women with polycystic ovary syndrome., The 17th International Congress of Endocrinology and the 15th Annual Meeting of the Chinese Society of Endocrinology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum vitamin D concentration is independently associated with anti-Mullerian hormone and obesity measures in Hong Kong Chinese women with polycystic ovary syndrome, The 17th International Congress of Endocrinology and the 15th Annual Meeting of the Chinese Society of Endocrinology. 2016.
Wong C.W., Lam K.W., Lee C.L., Yeung W.S.B., Zhao W.E., Ho P.C., Oue J.P. and Chiu C.N., The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa-zona pellucida binding, Human Reproduction. 2017, 32: 733-742.
Yung S.F.S., Cheng M.C.M., Ma W.S.P. and Ho P.C., Candida glabrata chorioamnionitis and fungaemia complicating pregnancy following intrauterine insemination: Case report and review of the literature, 25th Asian & Oceanic Congress of Obstetrics and Gynaecology (AOCOG) 2017 (The Journal of Obstetrics and Gynaecology Research). Wiley, 2017, 43, Issue Supplement S1: 140.


Researcher : Hui MN

List of Research Outputs

Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-b/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.


Researcher : Hui PW

Project Title:31st British International Congress of Obstetrics & Gynaecology 2007 A rare cause of Thrombocytopenia in Pregnancy-EDTA-dependent Pseudothrombocytopenia
Investigator(s):Hui PW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2007




Researcher : JIANG Y

List of Research Outputs

JIANG Y., Siu K.Y., WANG J., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., Hexokinase II (HK2) regulates stemness of ovarian cancer cells, AACR Annual Meeting 2017.
WANG J., Siu K.Y., JIANG Y., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., PFKP and PFKFB3 modulate cancer metabolic switch and chemoresistance to cisplatin in ovarian cancer, AACR Annual Meeting 2017.


Researcher : KOTTAWATTA KSA

List of Research Outputs

WANG Z., KOTTAWATTA K.S.A., Kodithuwakku S.P. and Lee C.K.F., The effect of Mancozeb on ER and Wnt/β-catenin pathway during embryo implantation in vitro cell model. P15, The Hong Kong Society of Endocrinology, Metabolism and Reproduction 33rd Annual Scientific Meeting, 20 Nov, 2016, Hong Kong. 2016.
WANG Z., KOTTAWATTA K.S.A., Kodithuwakku S.P. and Lee C.K.F., The mechanistic action of fungicide Mancozeb in suppressing spheroids attachment onto Endometrial epithelial cells. P-03, HKU-QMH Assisted Reproduction Programme, 30th Anniversary Celebration Symposium. 10-13, Nov, 2016, Hong Kong and Shenzhen. 2016.


Researcher : Kan SYA

List of Research Outputs

Chiu T.A., Chu W.Y., Kan S.Y.A. and Chung B.H.Y., What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). Medcom Limited, 2016, 21(4): 298,311-314.
Chu W.Y., LEUNG K.C., Mak A.S.L., Chiu T.A., MAK C.C.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong V.C.N., Lee S.L., Marshall C., Scherer S., Kan S.Y.A. and Chung B.H.Y., Use of clinical chromosomal microarray in Hong Kong Chinese patients with autism spectrum disorder - Implication of a copy number variation involving DPP10, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Chung B.H.Y., Mak S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Chan Y.K., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Fung C.W. and Lee S.L., Use of chromosomal microarray in Hong Kong patients with autism spectrum disorder - implication of a copy number variation involving DPP10, ASHG 2016, Vancouver, Canada, 18-22 October 2016.
LEUNG K.C., Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K., Ip J.K.J., Yang W., Lau Y.L. and Chung B.H.Y., Identification of a novel homozygous missense mutation in ABR causing cerebellar hypoplasia with early lethality, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Lau C.T., Kan S.Y.A., Shek N.W.M., Tam P.K.H. and Wong K.K.Y., Is congenital pulmonary airway malformation really a rare disease? Result of a prospective registry with universal antenatal screening program, Pediatric Surgery International. 2017, 33(1): 105-108.
Lee H.L.H., Mak A.S.L., Kou K.O.T., Poon C.F., Wong W.S., Chiu K.H., Au H.H.L., Chan Y.K., Kan S.Y.A., Tang M.H.Y. and Leung K.Y., An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations, Hemoglobin. 2016, 40(6): 431-434.


Researcher : Ko KYJ

List of Research Outputs

Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.


Researcher : Kou KOT

List of Research Outputs

Lee H.L.H., Mak A.S.L., Kou K.O.T., Poon C.F., Wong W.S., Chiu K.H., Au H.H.L., Chan Y.K., Kan S.Y.A., Tang M.H.Y. and Leung K.Y., An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations, Hemoglobin. 2016, 40(6): 431-434.


Researcher : LEUNG LL

List of Research Outputs

MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.


Researcher : LIANG R

List of Research Outputs

Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-b/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.
LIANG R., Yung M.H., Ngan H.Y.S. and Chan D.W., BCL2A1 plays a biphasic role in ovarian cancer progression: promoting cell survival and inhibiting cell proliferation, Cold Spring Harbour Asia: Cancer & Metabolism. Suzhou Dushu Lake Conference Center, Suzhou, PR China, 19 to 23rd, Sept., 2016.. 2016.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.


Researcher : Lam CW

Project Title:The first prospective second generation newborn screening in Hong Kong
Investigator(s):Lam CW, Chan AYW, Mak CM
Department:Pathology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:10/2012


Project Title:Food
Investigator(s):Lam CW, Wang M
Department:Pathology
Source(s) of Funding:Seed Funding for Strategic Research Theme
Start Date:09/2013


Project Title:Undiagnosed diseases program for ending diagnostic odyssey
Investigator(s):Lam CW
Department:Pathology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:11/2014
Completion Date:10/2017


Project Title:Regulatory signatures of two novel prognostic metabotypes of lung adenocarcinomas: integrated analysis of transcriptomics and metabonomics of malignant pleural effusions
Investigator(s):Lam CW
Department:Pathology
Source(s) of Funding:General Research Fund (GRF)
Start Date:09/2016


Project Title:2016 ASHG Annula Meeting; Adenylate kinase 9 (AK9) mutation is a novel disease gene for congenital myasthenic syndrome with limb girdle myasthenia
Investigator(s):Lam CW
Department:Pathology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2016
Completion Date:10/2016


Project Title:Clinical application of pleural fluid fatty acid synthase and pleural fluid total free fatty acids as cancer biomarkers in malignant pleural effusions
Investigator(s):Lam CW
Department:Pathology
Source(s) of Funding:Health and Medical Research Fund - Mini Grant
Start Date:06/2017


List of Research Outputs

Tse K.Y., Cheung V.Y.T., Lam C.W., Lee E.Y.P., Ngan H.Y.S. and Khong P.L., Successful Treatment of a Pararenal Pregnancy Using High-Dose Methotrexate Regimen A Case Report, Journal of Reproductive Medicine. United States, Journal of Reproductive Medicine, Inc., 2016, 61 issue 11-12: 592-594.


Researcher : Lam KW

List of Research Outputs

Wong C.W., Lam K.W., Lee C.L., Yeung W.S.B., Zhao W.E., Ho P.C., Oue J.P. and Chiu C.N., The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa-zona pellucida binding, Human Reproduction. 2017, 32: 733-742.


Researcher : Lam YH

Project Title:11th World Congress on Ultrasound in Obstetrics and Gynecology Integrated First and Second Trimester Screening for Down Syndrome
Investigator(s):Lam YH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2001




Researcher : Lao TTH

Project Title:The First Congress on Obstetrics, Gynecology & Infertility Does Impaired Glucose Tolerance Impact on Pregnancy Outcome?
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/1999


Project Title:Dietary caloric intake and the development of gestational diabetes mellitus in at-risk Chinese women
Investigator(s):Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:Elevated TNF-α in gestational diabetes mellitus-cause or consequence?
Investigator(s):Lao TTH, Leung WC, Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The relationship between the antioxidant defense system with the development of gestational diabetes mellitus and its complications in the Chinese population.
Investigator(s):Lao TTH
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2005




Researcher : Lau ETK

List of Research Outputs

Chu W.Y., LEUNG K.C., Mak A.S.L., Chiu T.A., MAK C.C.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong V.C.N., Lee S.L., Marshall C., Scherer S., Kan S.Y.A. and Chung B.H.Y., Use of clinical chromosomal microarray in Hong Kong Chinese patients with autism spectrum disorder - Implication of a copy number variation involving DPP10, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Chung B.H.Y., Mak S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Chan Y.K., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Fung C.W. and Lee S.L., Use of chromosomal microarray in Hong Kong patients with autism spectrum disorder - implication of a copy number variation involving DPP10, ASHG 2016, Vancouver, Canada, 18-22 October 2016.
Siu C.W.K., Lam C.W., Mak C.M., Lau E.T.K., Tang M.H.Y., Tang W.F., Poon-Mak R.S., Lee C.C., Hung S.F., Leung P.W., Kwong K.L., Yau E.K., Ng G.S., Fong N.C. and Chan K.Y., Diagnostic yield of array CGH in patients with autism spectrum disorder in Hong Kong, Clinical and Translational Medicine. 2016, 5.


Researcher : Lau SK

List of Research Outputs

Liu S., Chu K.H., Wei N., Lau S.K., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Circulating micro-RNAs as biomarkers for detection of cervical cancer, International Papillomavirus Conference. 2017.


Researcher : Lau YLE

List of Research Outputs

Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.


Researcher : Lee CKF

Project Title:Functional characterization of VAD1.3, a novel acrosome-specific protein by conditional tissue-specific gene inactivation
Investigator(s):Lee CKF, Cheah KSE, Yeung WSB, Luk JMC, Lee NPY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006


Project Title:Environmental Screening, Computational and Biological Characterization of Endocrine Disruptors, in Respect to Receptor Binding, Embryo and Gonad Physiology
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2009


Project Title:Human embryonic stem cell-derived trophoblastic cells for the development of a novel implantation model
Investigator(s):Lee CKF, Ng EHY, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Studies on Human Endometrial Receptivity by profiling and function studies of surface proteins of human endometrial cell lines
Investigator(s):Lee CKF, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2015


Project Title:Bisphenol A analogues: Mechanistic actions on Embryo implantation and Endometrial Receptivity
Investigator(s):Lee CKF, Ng EHY, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:Mechanistic study of endocrine disrupting chemical Mancozeb (Manganese ethylene bisdithiocarbamate) on implantation
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


List of Research Outputs

FAN H., Yeung W.S.B. and Lee C.K.F., Bisphenol aA analogues: effect on gene activation and spheroid attachment in endometrial epithelial iIshikawa cells, 33th Annual Scientific Meeting of Hong Kong society of Endocrinology, Metabolism and Reproduction. Hong Kong, China. 2016.
FAN H., Yeung W.S.B. and Lee C.K.F., Effect of bisphenol aA analogues on gene regulation and spheroid attachment in endometrial epithelial iIshikawa cells, 21st Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong. Hong Kong, China. 2016.
FAN H., Wong C.K.C., Yeung W.S.B. and Lee C.K.F., Molecular and functional approach to delineate the effect of bisphenol analogues on the receptivity of human endometrial epithelial cells, 30th Anniversary Celebration of the HKU-QMH Assisted Reproduction Programme. Shenzhen, China. 2016.
Lee C.K.F., A novel model for determination of endometrial receptivity. HKU-QMH O&G Assisted Reproduction Program, 30th anniversary Celebration Symposium. Shenzhen., 2016.
Lee C.K.F., Determination of endometrial receptivity. S-5.2. HKU-QMH O&G Assisted Reproduction Program, 30th anniversary Celebration Symposium. Hong Kong., 2016.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
Sze C.W.S., WANG S., NG T.B., Lee C.K.F. and Lam J.K.W., Steroidogenic effect of Erxian decoction for relieving menopause via the p-Akt/PKB pathway in vitro and in vivo, 11th European Congress on Menopause and Andropause.. The Netherland (EMAS 2017), 2017.
WANG S., CHEUNG H.P., Tong Y., LU J., Ng T.B., Zhang Y., Zhang Z., Lee C.K.F., Lam J.K.W. and Sze C.W.S., Steroidogenic effect of Erxian decoction for relieving menopause via the p-Akt/PKB pathway in vitro and in vivo, Journal of Ethnopharmacology. 2017, 195: 188-195.
WANG X., NG T.B., Lee C.K.F. and Sze C.W.S., Use of rodent models in the study of menopausal symptoms: A review of experimental studies., 1th European Congress on Menopause and Andropause.. Netherland (EMAS 2017), 2017.
WANG Z., KOTTAWATTA K.S.A., Kodithuwakku S.P. and Lee C.K.F., The effect of Mancozeb on ER and Wnt/β-catenin pathway during embryo implantation in vitro cell model. P15, The Hong Kong Society of Endocrinology, Metabolism and Reproduction 33rd Annual Scientific Meeting, 20 Nov, 2016, Hong Kong. 2016.
WANG Z., KOTTAWATTA K.S.A., Kodithuwakku S.P. and Lee C.K.F., The mechanistic action of fungicide Mancozeb in suppressing spheroids attachment onto Endometrial epithelial cells. P-03, HKU-QMH Assisted Reproduction Programme, 30th Anniversary Celebration Symposium. 10-13, Nov, 2016, Hong Kong and Shenzhen. 2016.


Researcher : Lee CL

List of Research Outputs

Chan R.W.S., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Co-culture with macrophages enhances the clonogenic and invasion activity of endometriotic stromal cells, Cell Proliferation. John Wiley & Sons Ltd, 2017, 50: 1-9.
Lee C.L., Doris Zimmern HKU-Cambridge Hughes Hall Fellowship, The University of Hong Kong. 2017.
Lee C.L., Yeung W.S.B. and Chiu C.N., Soluble Human Leukocyte Antigen G5 Polarizes Decidual Macrophage Differentiation from Monocyte to Promotes Fetomaternal Tolerance and Placental Development, Hong Kong Society of Endocrinology, Metabolism and Reproduction - Annual Scientific Meeting. 2016.
Lee C.L., Yeung W.S.B. and Chiu C.N., Soluble Human Leukocyte Antigen G5 Polarizes Decidual Macrophage Differentiation from Monocyte to Promotes Fetomaternal Tolerance and Placental Development, Hong Kong Society of Endocrinology, Metabolism and Reproduction - Annual Scientific Meeting. 20 Nov 2016, HK. 2016.
Wong C.W., Lam K.W., Lee C.L., Yeung W.S.B., Zhao W.E., Ho P.C., Oue J.P. and Chiu C.N., The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa-zona pellucida binding, Human Reproduction. 2017, 32: 733-742.


Researcher : Lee CYL

List of Research Outputs

Chen C.H., Lee C.Y.L., Fong S.W., Wong C.C.Y., Ng E.H.Y. and Yeung W.S.B., Hyperglycemia impedes definitive endoderm differentiation of human embryonic stem cells by modulating histone methylation patterns, Cell and Tissue Research. 2017, 2017 Jun;368(3):563-578.


Researcher : Lee HLH

List of Research Outputs

Lee H.L.H., Mak A.S.L., Kou K.O.T., Poon C.F., Wong W.S., Chiu K.H., Au H.H.L., Chan Y.K., Kan S.Y.A., Tang M.H.Y. and Leung K.Y., An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations, Hemoglobin. 2016, 40(6): 431-434.


Researcher : Lee VCY

List of Research Outputs

Chan M.K.D., Cheung K.W., Yung S.F., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., A randomized double-blind controlled trial of the use of dydrogesterone in women with threatened miscarriage in the first trimester: study protocol for a randomized controlled trial, Trials. 2016, 17.
Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., A randomized double-blinded controlled trial of hCG as luteal phase support in natural cycle frozen embryo transfer, Human Reproduction. 2017, 32: 1130-1137.
Li R.H.W., Yeung T.W.Y., Lee V.C.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Comparing the inter-cycle variation of serum anti-Mullerian hormone and antral follicle count measurements in predicting ovarian response before IVF, 32nd Annual Meeting, European Society of Human Reproduction and Embryology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek A.C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum Vitamin D Concentration Is Independently Associated With Anti-mullerian Hormone Level And Obesity Measures In Hong Kong Chinese Women With Polycystic Ovary Syndrome, 17th International Congress of Endocrinology cum 15th Annual Meeting of Chinese Society of Endocrinology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum Vitamin D concentration is independently associated with anti-Mullerian hormone level and obesity measures in Hong Kong Chinese women with polycystic ovary syndrome., The 17th International Congress of Endocrinology and the 15th Annual Meeting of the Chinese Society of Endocrinology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum vitamin D concentration is independently associated with anti-Mullerian hormone and obesity measures in Hong Kong Chinese women with polycystic ovary syndrome, The 17th International Congress of Endocrinology and the 15th Annual Meeting of the Chinese Society of Endocrinology. 2016.


Researcher : Leung KY

List of Research Outputs

Lee H.L.H., Mak A.S.L., Kou K.O.T., Poon C.F., Wong W.S., Chiu K.H., Au H.H.L., Chan Y.K., Kan S.Y.A., Tang M.H.Y. and Leung K.Y., An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations, Hemoglobin. 2016, 40(6): 431-434.


Researcher : Leung THY

List of Research Outputs

Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-b/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.
JIANG Y., Siu K.Y., WANG J., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., Hexokinase II (HK2) regulates stemness of ovarian cancer cells, AACR Annual Meeting 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.
WANG J., Siu K.Y., JIANG Y., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., PFKP and PFKFB3 modulate cancer metabolic switch and chemoresistance to cisplatin in ovarian cancer, AACR Annual Meeting 2017.


Researcher : Li RHW

Project Title:Role of adrenomedullin and inflammatory mediators in pathogenesis of tubal ectopic pregnancy
Investigator(s):Li RHW, Cheung BMY, O WS, Lee CKF, Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:32th Annual Meeting of the European Society of Human Reproduction and Embryology; Comparing the inter-cycle variation of serum anti-Mullerian hormone and antral follicle count measurements in predicting ovarian response before IVF
Investigator(s):Li RHW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2016
Completion Date:07/2016


List of Research Outputs

Chan M.K.D., Cheung K.W., Yung S.F., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., A randomized double-blind controlled trial of the use of dydrogesterone in women with threatened miscarriage in the first trimester: study protocol for a randomized controlled trial, Trials. 2016, 17.
Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., A randomized double-blinded controlled trial of hCG as luteal phase support in natural cycle frozen embryo transfer, Human Reproduction. 2017, 32: 1130-1137.
Li R.H.W., A critical look of ovarian reserve testing in fertile and infertile women., Celebration of Life: 30th Anniversary Symposium of HKU-QMH Assisted Reproduction Programme. 2016.
Li R.H.W., Yeung T.W.Y., Lee V.C.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Comparing the inter-cycle variation of serum anti-Mullerian hormone and antral follicle count measurements in predicting ovarian response before IVF, 32nd Annual Meeting, European Society of Human Reproduction and Embryology. 2016.
Li R.H.W., Editorial Board Member, British Journal of Obstetrics and Gynaecology. 2017.
Li R.H.W., Editorial Board Member, Journal of Paediatrics, Obstetrics and Gynaecology. 2017.
Li R.H.W., Long-acting reversible contraception, 25th Asian and Oceanic Congress of Obstetrics and Gynaecology. 2017.
Li R.H.W., Myths and updates in emergency contraception., 25th Asian and Oceanic Congress of Obstetrics and Gynaecology. 2017.
Li R.H.W., Cheung T.M., Yeung W.S.B. and Ng E.H.Y., Relative importance of the different components of the Bologna criteria for predicting poor ovarian response in assisted reproduction., 11th European Congress on Menopause and Andropause. 2017.
Li R.H.W., Lam K.S.L., Tam S., Shek A.C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum Vitamin D Concentration Is Independently Associated With Anti-mullerian Hormone Level And Obesity Measures In Hong Kong Chinese Women With Polycystic Ovary Syndrome, 17th International Congress of Endocrinology cum 15th Annual Meeting of Chinese Society of Endocrinology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum Vitamin D concentration is independently associated with anti-Mullerian hormone level and obesity measures in Hong Kong Chinese women with polycystic ovary syndrome., The 17th International Congress of Endocrinology and the 15th Annual Meeting of the Chinese Society of Endocrinology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum vitamin D concentration is independently associated with anti-Mullerian hormone and obesity measures in Hong Kong Chinese women with polycystic ovary syndrome, The 17th International Congress of Endocrinology and the 15th Annual Meeting of the Chinese Society of Endocrinology. 2016.


Researcher : Li TKT

List of Research Outputs

Li T.K.T., 妊娠毒血症(子癇前症), Health Action (健康動力). 2016, 120: 54.


Researcher : Liao S

Project Title:Molecular regulation of meiotic resumption and chromosome segregation in mouse and human oocytes
Investigator(s):Liao S
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014




Researcher : Liu S

List of Research Outputs

Liu S., Chu K.H., Wei N., Lau S.K., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Circulating micro-RNAs as biomarkers for detection of cervical cancer, International Papillomavirus Conference. 2017.
Liu S., HPV-related micro-RNAs in cervical pre-malignant lesions and cancer, Asia-Oceania Research Organisation in Genital Infection and Neoplasia (AOGIN 2016). 2016.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.


Researcher : Liu W

Project Title:Roles of microRNA lethal-7 on blastulation of mice embryos
Investigator(s):Liu W, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2014


Project Title:SRF 2015 annual Conference; Mechanism of microRNA lethal-7 in embryo dormancy in mice
Investigator(s):Liu W
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2015


List of Research Outputs

NIU Z., Pang T.K.R., Liu W. and Yeung W.S.B., Comparison and Characterization of Extracellular Vesicles isolated from endometrial cell lines by different methodologies, SSR 49th Annual Meeting - Society for the Study of Reproduction. 2016, 210.


Researcher : Lui MWE

List of Research Outputs

Lui M.W.E. and Cheung V.Y.T., Three-dimensional versus two-dimensional laparoscopy for ovarian cystectomies: a prospective randomized study, 25th Asian and Oceanic Congress of Obstetrics and Gynaecology. 2017.


Researcher : MAK SL

List of Research Outputs

Chan D.W., MAK S.L. and Ngan H.Y.S., The significance of lipid metabolism in peritoneal metastases of ovarian cancer, Cold Spring Harbour Asia: Cancer & Metabolism. Suzhou Dushu Lake Conference Center, Suzhou, PR China, 19 to 23rd, Sept., 2016.. 2016.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.


Researcher : Ma WSP

List of Research Outputs

Ma W.S.P. and Pun T.C., Prevalence of Domestic Violence in Hong Kong Chinese Women Presenting with Urinary Symptoms, PLoS One. 2016, 11(7).
Yung S.F.S., Cheng M.C.M., Ma W.S.P. and Ho P.C., Candida glabrata chorioamnionitis and fungaemia complicating pregnancy following intrauterine insemination: Case report and review of the literature, 25th Asian & Oceanic Congress of Obstetrics and Gynaecology (AOCOG) 2017 (The Journal of Obstetrics and Gynaecology Research). Wiley, 2017, 43, Issue Supplement S1: 140.


Researcher : Mak ASL

List of Research Outputs

Chu W.Y., LEUNG K.C., Mak A.S.L., Chiu T.A., MAK C.C.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong V.C.N., Lee S.L., Marshall C., Scherer S., Kan S.Y.A. and Chung B.H.Y., Use of clinical chromosomal microarray in Hong Kong Chinese patients with autism spectrum disorder - Implication of a copy number variation involving DPP10, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Lee H.L.H., Mak A.S.L., Kou K.O.T., Poon C.F., Wong W.S., Chiu K.H., Au H.H.L., Chan Y.K., Kan S.Y.A., Tang M.H.Y. and Leung K.Y., An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations, Hemoglobin. 2016, 40(6): 431-434.


Researcher : NIU Z

List of Research Outputs

NIU Z., Pang T.K.R., Liu W. and Yeung W.S.B., Comparison and Characterization of Extracellular Vesicles isolated from endometrial cell lines by different methodologies, SSR 49th Annual Meeting - Society for the Study of Reproduction. 2016, 210.


Researcher : Ng EHY

Project Title:The 17th IFFS World Congress on Fertility and Sterility 1) Measurement of Serum CA-125 Concentrations Does not Improve the Value of Chlamydia Trachomatis Antibody (CAT) in Predicting Tubal Pathology at Laparoscopy 2) A Comparison of the Pain Levels During Egg Collection and Postoperative Side Effects Using Paracervical Block with and without Conscious Sedation
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2001


Project Title:Comparison of the prevalence of polycystic ovary only and polycystic ovary syndrome between two different ethnic populations
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:A randomized controlled trial on the effect of endometrial injury on improving the live birth rate in infertile women undergoing in vitro fertilization treatment with repeated implantation failure
Investigator(s):Ng EHY, Chai J, Li RHW, Lee CKF, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2015
Completion Date:05/2017


Project Title:Myometrial cells modulate the activities of endometrial mesenchymal-like stem cells
Investigator(s):Ng EHY, Lee CKF, Yeung WSB, Chan RWS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation.
Investigator(s):Ng EHY, Yeung WSB, Chan RWS, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2017


List of Research Outputs

Chan C.H.Y., Lau H.P., Tam M.Y.J. and Ng E.H.Y., A longitudinal study investigating the role of decisional conflicts and regret and short-term psychological adjustment after IVF treatment failure, Human Reproduction. 2016, 31: 1-9.
Chan C.H.Y., Ng E.H.Y., Chan C.L.W., Tam M.Y.J., WONG S. and Lau H.P., Effects of Fertility Treatment Decisions on Psychosocial Well-Being: A Study with Women Undergoing in vitro fertilization (IVF) treatment in Hong Kong, Asia mental health conference 2016, Hong Kong. 2016.
Chan C.H.Y., Chan T.H.Y., Tam M.Y.J., WONG S., Ng E.H.Y. and Chan C.L.W., Preferred roles in treatment decision-making, decisional conflict and depression: A longitudinal study of Chinese women making decisions on IVF treatment, Human Reproduction. 2016, 31(Suppl 1): i348.
Chan M.K.D., Cheung K.W., Yung S.F., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., A randomized double-blind controlled trial of the use of dydrogesterone in women with threatened miscarriage in the first trimester: study protocol for a randomized controlled trial, Trials. 2016, 17.
Chan R.W.S., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Co-culture with macrophages enhances the clonogenic and invasion activity of endometriotic stromal cells, Cell Proliferation. John Wiley & Sons Ltd, 2017, 50: 1-9.
Chen C.H., Lee C.Y.L., Fong S.W., Wong C.C.Y., Ng E.H.Y. and Yeung W.S.B., Hyperglycemia impedes definitive endoderm differentiation of human embryonic stem cells by modulating histone methylation patterns, Cell and Tissue Research. 2017, 2017 Jun;368(3):563-578.
Cheng H.C., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., The role of myometrium in maintaining the endometrial mesenchymal-like stem cells through secretion of matrix metalloproteinase 3, Hong Kong Society of Endocrinology Metabolism & Reproduction, Hong Kong, 20th Nov 2016. Abstract P-03: p 17.
Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., A randomized double-blinded controlled trial of hCG as luteal phase support in natural cycle frozen embryo transfer, Human Reproduction. 2017, 32: 1130-1137.
Li J., Ng E.H.Y., Stener-Victorin E., Hu Z., Wu W., Lai M., Wu T. and Ma H., Comparison of acupuncture pretreatment followed by letrozole versus letrozole alone on live birth in anovulatory infertile women with polycystic ovary syndrome: a study protocol for a randomised controlled trial, British Medical Journal Open. 2016, 6(10): e010955.
Li R.H.W., Yeung T.W.Y., Lee V.C.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Comparing the inter-cycle variation of serum anti-Mullerian hormone and antral follicle count measurements in predicting ovarian response before IVF, 32nd Annual Meeting, European Society of Human Reproduction and Embryology. 2016.
Li R.H.W., Cheung T.M., Yeung W.S.B. and Ng E.H.Y., Relative importance of the different components of the Bologna criteria for predicting poor ovarian response in assisted reproduction., 11th European Congress on Menopause and Andropause. 2017.
Li R.H.W., Lam K.S.L., Tam S., Shek A.C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum Vitamin D Concentration Is Independently Associated With Anti-mullerian Hormone Level And Obesity Measures In Hong Kong Chinese Women With Polycystic Ovary Syndrome, 17th International Congress of Endocrinology cum 15th Annual Meeting of Chinese Society of Endocrinology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum Vitamin D concentration is independently associated with anti-Mullerian hormone level and obesity measures in Hong Kong Chinese women with polycystic ovary syndrome., The 17th International Congress of Endocrinology and the 15th Annual Meeting of the Chinese Society of Endocrinology. 2016.
Li R.H.W., Lam K.S.L., Tam S., Shek C.C., Lee V.C.Y., Ho P.C. and Ng E.H.Y., Serum vitamin D concentration is independently associated with anti-Mullerian hormone and obesity measures in Hong Kong Chinese women with polycystic ovary syndrome, The 17th International Congress of Endocrinology and the 15th Annual Meeting of the Chinese Society of Endocrinology. 2016.
Tam M.Y.J., Chan C.H.Y., Ng E.H.Y., Chan C.L.W., Chan T.H.Y., WONG S., Wong A.W.Y. and Chan C.K.L., Abstracts of the 32nd Annual Meeting of the European Society of Human Reproduction and Embryology, Human Reproduction. 2016, 31: i1-i513.
Tam M.Y.J., Chan C.H.Y., Ng E.H.Y., Chan C.L.W., Chan H.Y., WONG S., Wong W.Y. and Chan K.L., Impact of Treatment Decisions and Significance of Cultural Beliefs in Predicting Quality of Life of Chinese Infertile Women., Impact of Treatment Decisions and Significance of Cultural Beliefs in Predicting Quality of Life of Chinese Infertile Women. 2016.
Tam M.Y.J., Chan C.H.Y., Ng E.H.Y., Chan C.L.W., WONG S., Wong W.Y. and Chan K.L., Impact of treatment decisions and significance of cultural beliefs in predicting quality of life of Chinese infertile women. Human Reproduction, Human Reproduction. 2016, 31(Suppl 1): i358.
Wang R., Kim B.V., Wely M.V., Johnson N.P., Costello M.F., Zhang H., Ng E.H.Y., Legro R.S., Bhattacharya S., Norman R.J. and Mol B.W.J., Treatment strategies for women with WHO group II anovulation: systematic review and network meta-analysis, British Medical Journal Open. 2017, 356: j138.
XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Characterization of Endometrial Mesenchymal-like Stem Cells Activity in Different Endometrial Layers and During the Menstrual Cycle, 49th Society for the Study of Reproduction. 2016.
Xu S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle, Experimental Cell Research. Elsevier Inc, 2017, 350(1): 184-189.


Researcher : Ng TY

Project Title:A propective randomised controlled trial: prevention of lymphedema by omentoplasty after pelvic lymphadenectomy
Investigator(s):Ng TY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Low Budget High Impact Programme
Start Date:11/2001




Researcher : Ngai CSW

Project Title:Vaginal misoprostol for first trimester termination of pregnancy prior to 9 weeks of gestation
Investigator(s):Ngai CSW, Tang FOS, Chan YM, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:05/1999


Project Title:Cervical assessment in prediction of preterm labour: is three-dimensional ultrasonography a better choice?
Investigator(s):Ngai CSW, Lao TTH, Chen M, Leung KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Multiple pregnancy and gestational diabetes: a physiological response or a pathologic condition?
Investigator(s):Ngai CSW, Lao TTH, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The XIXth Asian and Oceanic Congress of Obstetrics & Gynaecology Should We Screen Sexually Transmitted Diseases for Women Requesting for Termination of Pregnancy?
Investigator(s):Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2005




Researcher : Ngan HYS

Project Title:High dose cis-platinum and cyclophosphamide vs taxol in ovarian cancer
Investigator(s):Ngan HYS, Wong LCR
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:07/1994


Project Title:Clinical significance and application of HPV-related microRNAs in cervical pre-maglinant lesions and cancer
Investigator(s):Ngan HYS, Liu S, Ng EKO, Cheung ANY, Chan KKL, Kwong A
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2013
Completion Date:08/2016


Project Title:Roles of HPV-E6 protein and CD55(+) population in regulating radio-resistance in cervical cancer cells
Investigator(s):Ngan HYS, Chan KKL, Leung THY, Cheung ANY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2013
Completion Date:10/2016


Project Title:Functional characterization of CD71(+) population and the roles of HPV-E6 protein in cervical cancer
Investigator(s):Ngan HYS, Chan KKL, Cheung ANY, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2014
Completion Date:10/2016


Project Title:Elucidating the potential role of CD109 as a cancer stem-like cell marker in cervical cancer
Investigator(s):Ngan HYS, Leung THY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2015
Completion Date:09/2016


Project Title:Investigation on the oncogenic roles of HPV-E6 and mCRPs in cervical cancer cells
Investigator(s):Ngan HYS, Leung THY, Siu KY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016


Project Title:Functional characterization of the roles of NR4A2 in cervical cancer cells
Investigator(s):Ngan HYS, Leung THY, Siu KY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


List of Research Outputs

CHEN K., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness via targeting GRB7, AACR Annual Meeting 2017. Walter E. Washington Convention Center W, American Association of Cancer Research.
CHEN R., Ngan H.Y.S. and Chan D.W., The AMPK/TAK1/NF-kB signaling axis is indispensable for modulating ovarian cancer cell metabolism and peritoneal metastases, The 21st Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong, 1-2 Dec, 2016.
CHEN R., Ngan H.Y.S. and Chan D.W., The roles of AMPK and TAK1/NF-kB signaling cascade in governing cancer cell aggressiveness in omental microenvironemnt, the 24th Biennial European Association for Cancer Research (EACR) Congress, 9-12 July, 2016, Manchester, UK. 2016.
Chan D.W., Yung M.H., Hardie D.G. and Ngan H.Y.S., AMP-activated protein kinase gamma-2 (AMPK-g2) subunit modulates AMPK activities to ensure ovarian cancer progression, AMPK 2016: NEW MECHANISMS and PHYSIOLOGY, November 11-16, 2016, Xiamen, China. 2016.
Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-b/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.
Chan D.W., MAK S.L. and Ngan H.Y.S., The significance of lipid metabolism in peritoneal metastases of ovarian cancer, Cold Spring Harbour Asia: Cancer & Metabolism. Suzhou Dushu Lake Conference Center, Suzhou, PR China, 19 to 23rd, Sept., 2016.. 2016.
Chow K.L., Tse K.Y., Cheung C.L., Wong K.W., Cheung A.N.Y., Wong W.C., Chan A.N.H., Yuen N.W.F., Ngan H.Y.S. and Ip P.C.P., The mitosis-specific marker phosphohistone-H3 (PHH3) is an independent prognosticator in uterine smooth muscle tumours: an outcome-based study, Histopathology. United Kingdom, Wiley, 2017, 70: 746-755.
Chuang L.T., Temin S., Camacho R., Dueñas-Gonzalez A., Feldman S., Gultekin M., Gupta V., Horton S., Jacob G., Kidd E.A., Lishimpi K., Nakisige C., Nam J.H., Ngan H.Y.S., Small W., Thomas G. and Berek J.S., Management and Care of Women With Invasive Cervical Cancer: American Society of Clinical Oncology Resource-Stratified Clinical Practice Guideline, Journal of Global Oncology. 2016, 2: 311-340.
JIANG Y., Siu K.Y., WANG J., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., Hexokinase II (HK2) regulates stemness of ovarian cancer cells, AACR Annual Meeting 2017.
Janda M., Gebski V., Davies L.C., Forder P., Brand A., Hogg R., Jobling T.W., Land R., Manolitsas T., Nascimento M., Neesham D., Nicklin J.L., Oehler M.K., Otton G., Perrin L., Salfinger S., Hammond I., Leung Y., Sykes P., Ngan H.Y.S., Garrett A., Laney M., Ng T.Y., Tam K., Chan K.K.L., Wrede C.D., Pather S., Simcock B., Farrell R., Robertson G., Walker G., Armfield H.R., Graves N., McCartney A.J. and Obermair A., Effect of Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy on Disease-Free Survival Among Women With Stage I Endometrial Cancer: A Randomized Clinical Trial, JAMA. 2017, 317(12): 1224-1233.
LIANG R., Yung M.H., Ngan H.Y.S. and Chan D.W., BCL2A1 plays a biphasic role in ovarian cancer progression: promoting cell survival and inhibiting cell proliferation, Cold Spring Harbour Asia: Cancer & Metabolism. Suzhou Dushu Lake Conference Center, Suzhou, PR China, 19 to 23rd, Sept., 2016.. 2016.
Liu S., Chu K.H., Wei N., Lau S.K., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Circulating micro-RNAs as biomarkers for detection of cervical cancer, International Papillomavirus Conference. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.
Ngan H.Y.S., 16th Biennial Meeting of the International Gynecologic Cancer Society (IGCS), Lisbon, Portugal, October 29-31, PSTT and ETT: an analysis of the world data set. 2016.
Ngan H.Y.S., ASCO guideline in the management of cervical cancer , The 2nd International Symposium on Gynecologic Oncology and APAGE Regional Meeting, Seoul, Korea, February 10-11. 2017.
Ngan H.Y.S., Advances in the Mangement of Germ cell and stromal cell tumour of the ovary , 19th Annual Meeting of the Chinese Society of Clinical Oncology (CSCO), Xiamen, China, September 21-25. 2016.
Ngan H.Y.S., Advances in the Mangement of Germ cell and stromal cell tumour of the ovary, 19th Annual Meeting of the Chinese Society of Clinical Oncology (CSCO), Xiamen, China, September 21-25, 2016.
Ngan H.Y.S., Cancer Prevention in the Most Populous Country in the World , 2017 IFCPC World Congress for Cervical Pathology and Colposcopy, Orlando, Florida, USA, April 4-7. 2017.
Ngan H.Y.S., Local Lynparza Experience Sharing , The Lynparza Hong Kong Launch Meeting: Transforming Outcomes in Ovarian Cancer, Hong Kong, September 6. 2016.
Ngan H.Y.S., Local Lynparza Experience Sharing, the Lynparza Hong Kong Launch Meeting: Transforming Outcomes in Ovarian Cancer, Hong Kong, September 6, 2016.
Ngan H.Y.S., Management of Cervical Intraepithelial Neoplasia, The 3rd Conference of Chinese Society for Colposcopy and Cervical Pathology, Beijng, May 18-21. 2017.
Ngan H.Y.S., Nerve sparing radical hysterectomy , The 2nd Asian Congress of Robotic Surgery (ARCS) 2016, Gyeongju, Korea, November 25-26. 2016.
Ngan H.Y.S., Nerve sparing radical hysterectomy, The 2nd Asian Congress of Robotic Surgery (ARCS) 2016, Gyeongju, Korea, November 25-26, 2016.
Ngan H.Y.S., Outcome of treatment for Gestational Trophoblastic Neoplasia – A multicenter retrospective study, The 56th Annual Meeting of the Japan Society of Gynecologic Oncology (“JSGO) and Asian Gynecologic Oncology Group (“AGOG”), Yonago, Japan, July 8-10. 2016.
Ngan H.Y.S., Outcome of treatment for Gestational Trophoblastic Neoplasia – A multicenter retrospective study, The 56th Annual Meeting of the Japan Society of Gynecologic Oncology (“JSGO) and Asian Gynecologic Oncology Group (“AGOG”), Yonago, Japan, July 8-10, 2016.
Ngan H.Y.S., PSTT and ETT: an analysis of the world data set, 16th Biennial Meeting of the International Gynecologic Cancer Society (IGCS), Lisbon, Portugal, October 29-31, 2016.
Ngan H.Y.S., Pitfalls in the diagnosis and management of endometrial cancer, 2016妇科肿瘤暨腔镜技术新进展研讨会, HKU-Shenzhen Hospital, Shenzhen, China, October 22. 2016.
Ngan H.Y.S., Pitfalls in the diagnosis and management of endometrial cancer, 2016妇科肿瘤暨腔镜技术新进展研讨会, HKU-Shenzhen Hospital, Shenzhen, China, October 22, 2016.
Ngan H.Y.S., Precision medicine in ovarian cancer, 中国医疗保健国际交流促进会 - 第三届华夏妇产科论坛, Beijing, April 20-22,. 2017.
Ngan H.Y.S., Role of Adjuvant Chemotherapy for Cervical Cancer, Asia-Oceania Research Organisation in Genital Infection and Neoplasia (“AOGIN”) 2016 Congress, Singapore, August 12-14, 2016.
Ngan H.Y.S., Role of Adjuvant Chemotherapy for Cervical Cancer, Asia-Oceania Research Organisation in Genital Infection and Neoplasia (“AOGIN”) 2016 Congress,Singapore, August 12-14. 2016.
Ngan H.Y.S., Surgical treatment of cervical cancer – can it be less radical , 25th Asian & Oceanic Congress of Obstetrics & Gynaecology (AOCOG), Hong Kong, June 16-18. 2017.
Ngan H.Y.S., The use of PARP inhibitors: The present and future, The 12th New Progress in Obstetrics & Gynaecology Academic Conference, Beijing, China, July 1-3. 2016.
Ngan H.Y.S., The use of PARP inhibitors: The present and future, The 12th New Progress in Obstetrics & Gynaecology Academic Conference, Beijing, China, July 1-3, 2016.
Ngan H.Y.S., Understanding pelvic anatomy through robotic surgery, 2nd Joint Minimally Invastive Surgery Symposium, Hong Kong, July 24. 2016.
Ngan H.Y.S., Understanding pelvic anatomy through robotic surgery, 2nd Joint Minimally Invastive Surgery Symposium, Hong Kong, July 24, 2016.
Ngu S.F., Wei N., Kwan T.T., Chu M.Y.M., Tse K.Y., Chan K.K.L. and Ngan H.Y.S., Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial., J Psychosom Obstet Gynaecol. 2017.
Ngu S.F., Chu M.Y.M., Ip P.C.P. and Ngan H.Y.S., Vulvar Hidradenitis Suppurativa: Is the Mass Malignant? , J Obstet Gynaecol Can.. 2017.
Tse K.Y., Lau S.K., Lui M.W., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Patient compliance with cervical smear surveillance in a shared-care setting, International Journal of Gynecology & Obstetrics. 2016.
Tse K.Y., Cheung V.Y.T., Lam C.W., Lee E.Y.P., Ngan H.Y.S. and Khong P.L., Successful Treatment of a Pararenal Pregnancy Using High-Dose Methotrexate Regimen A Case Report, Journal of Reproductive Medicine. United States, Journal of Reproductive Medicine, Inc., 2016, 61 issue 11-12: 592-594.
WANG J., Siu K.Y., JIANG Y., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., PFKP and PFKFB3 modulate cancer metabolic switch and chemoresistance to cisplatin in ovarian cancer, AACR Annual Meeting 2017.
YUNG M.H., ROSS F.A., HARDIE D.G., ZHAN J.B., Ngan H.Y.S. and Chan D.W., Bitter melon (Momordica charantia) extract functions as a natural AMPK activator and synergistically enhances cisplatin cytotoxicity in ovarian cancer cells, Integrat Cancer Ther. 2016, 15(3): 376-89.
Yung M.H., Ngan H.Y.S., Hardie D.G. and Chan D.W., Functional characterization of MAP30 protein from bitter melon (Momordica charantia) in combating ovarian cancer oncogenesis and chemoresistance, AMPK 2016: NEW MECHANISMS AND PHYSIOLOGY (The 9thInternational Symposium on AMP-activated Protein Kinase) Nov. 11-16, 2016, Xiamen, China. 2016.
Yung M.H., Ngan H.Y.S. and Chan D.W., Identification of MAP30 as a natural AMPK activator in targeting the tumorigenicity and chemoresistance of ovarian cancer cells, CSH Asia Conference on Cancer & Metabolism. 2016.


Researcher : Ngu SF

Project Title:Investigation of the Synergistic Anticancer Effect of Gedatolisib (PKI-587, PF-05212384) and Cisplatin in Ovarian Clear Cell Carcinoma (OCCC)
Investigator(s):Ngu SF, Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2017


List of Research Outputs

Lee E.Y.P., PERUCHO J.A.U., Vardhanabhuti V., He J., Siu W.K.S., Ngu S.F., Mayr N.A., Yuh W.T.C., Chan Q. and Khong P.L., Intravoxel incoherent motion MRI assessment of chemoradiation-induced pelvic bone marrow changes in cervical cancer and correlation with hematological toxicity, Journal of Magnetic Resonance Imaging. 2017.
Ngu S.F., Wei N., Kwan T.T., Chu M.Y.M., Tse K.Y., Chan K.K.L. and Ngan H.Y.S., Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial., J Psychosom Obstet Gynaecol. 2017.
Ngu S.F., Quiz on management of abnormal cervical cytology, 2016 HKU-SZH Gynaecological Oncology and Laparoscopic Surgery Conference . 2016.
Ngu S.F., Three Interesting Cases on Vulval Pathology, Clinical Pathological Conference, The Hong Kong Society for Colposcopy and Cervical Pathology. 2016.
Ngu S.F., Treatment option for invasive cervical cancer during pregnancy, The 25th Asian and Oceanic Congress of Obstetrics and Gynaecology (AOCOG) - ASGO Symposium. 2017.
Ngu S.F., Update in Cervical Cancer Management: Sharing of Local Experience with Targeted Therapy, The Hong Kong Society for Colposcopy and Cervical Pathology 15th Anniversary Symposium cum Biennial General Meeting. 2016.
Ngu S.F., Chu M.Y.M., Ip P.C.P. and Ngan H.Y.S., Vulvar Hidradenitis Suppurativa: Is the Mass Malignant? , J Obstet Gynaecol Can.. 2017.


Researcher : Ong CYT

Project Title:To determine the correlation of changes in maternal levels of pregnancy-associated plasma protein A (PAPP-A) and free [beta] human chorionic gonadotrophin (F[beta]-hCG) with placental development and fetal outcomes
Investigator(s):Ong CYT, Lao TTH, Leung WC, Leung KY, Lam HSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:First trimester prediction of fetal α-thalassaemia-1 with maternal serum markers, nuchal translucency measurement and three dimentional ultrasound measurement of placental volume
Investigator(s):Ong CYT, Chen M, Leung KY, Tang MHY, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Maternal serum level of ADAM 12 as an early marker of trisomy 21, trisomy 13 and trisomy 18
Investigator(s):Ong CYT, Lee CP, Lau ETK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2007




Researcher : Pang RTK

Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang TKR, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007


List of Research Outputs



Researcher : Pang TKR

Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang TKR, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007


List of Research Outputs

NIU Z., Pang T.K.R., Liu W. and Yeung W.S.B., Comparison and Characterization of Extracellular Vesicles isolated from endometrial cell lines by different methodologies, SSR 49th Annual Meeting - Society for the Study of Reproduction. 2016, 210.


Researcher : Pun TC

List of Research Outputs

Ma W.S.P. and Pun T.C., Prevalence of Domestic Violence in Hong Kong Chinese Women Presenting with Urinary Symptoms, PLoS One. 2016, 11(7).


Researcher : Shek NWM

List of Research Outputs

LEUNG K.C., Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K., Ip J.K.J., Yang W., Lau Y.L. and Chung B.H.Y., Identification of a novel homozygous missense mutation in ABR causing cerebellar hypoplasia with early lethality, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Lau C.T., Kan S.Y.A., Shek N.W.M., Tam P.K.H. and Wong K.K.Y., Is congenital pulmonary airway malformation really a rare disease? Result of a prospective registry with universal antenatal screening program, Pediatric Surgery International. 2017, 33(1): 105-108.


Researcher : Siu KY

Project Title:Effects of folate and folate receptor on ovarian and endometrial cancer: an in vitro study
Investigator(s):Siu KY, Cheung ANY
Department:Pathology
Source(s) of Funding:American Institute for Cancer Research (AICR) - General Award
Start Date:07/2006


Project Title:p21-activated kinase 4: a prognostic and therapeutic target for ovarian carcinoma?
Investigator(s):Siu KY, Cheung ANY, Ngan HYS
Department:Pathology
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:10/2007


List of Research Outputs

JIANG Y., Siu K.Y., WANG J., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., Hexokinase II (HK2) regulates stemness of ovarian cancer cells, AACR Annual Meeting 2017.
WANG J., Siu K.Y., JIANG Y., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., PFKP and PFKFB3 modulate cancer metabolic switch and chemoresistance to cisplatin in ovarian cancer, AACR Annual Meeting 2017.


Researcher : Tang FOS

Project Title:A prospective randomized comparison of sublingual and vaginal misoprostol in termination of pregnancy in the second trimester
Investigator(s):Tang FOS, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:10/2000




Researcher : Tang GWK

Project Title:A cross sectional health care study of Chinese perimenopausal women in Hong Kong
Investigator(s):Tang GWK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:01/1993




Researcher : Tang MHY

List of Research Outputs

Chu W.Y., LEUNG K.C., Mak A.S.L., Chiu T.A., MAK C.C.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong V.C.N., Lee S.L., Marshall C., Scherer S., Kan S.Y.A. and Chung B.H.Y., Use of clinical chromosomal microarray in Hong Kong Chinese patients with autism spectrum disorder - Implication of a copy number variation involving DPP10, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Chung B.H.Y., Mak S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Chan Y.K., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Fung C.W. and Lee S.L., Use of chromosomal microarray in Hong Kong patients with autism spectrum disorder - implication of a copy number variation involving DPP10, ASHG 2016, Vancouver, Canada, 18-22 October 2016.
LEUNG K.C., Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Tang M.H.Y., Kan S.Y.A., Chan Y.K., Ip J.K.J., Yang W., Lau Y.L. and Chung B.H.Y., Identification of a novel homozygous missense mutation in ABR causing cerebellar hypoplasia with early lethality, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Lee H.L.H., Mak A.S.L., Kou K.O.T., Poon C.F., Wong W.S., Chiu K.H., Au H.H.L., Chan Y.K., Kan S.Y.A., Tang M.H.Y. and Leung K.Y., An Unusual Hydrops Fetalis Associated with Compound Heterozygosity for Krüppel-like Factor 1 mutations, Hemoglobin. 2016, 40(6): 431-434.
Siu C.W.K., Lam C.W., Mak C.M., Lau E.T.K., Tang M.H.Y., Tang W.F., Poon-Mak R.S., Lee C.C., Hung S.F., Leung P.W., Kwong K.L., Yau E.K., Ng G.S., Fong N.C. and Chan K.Y., Diagnostic yield of array CGH in patients with autism spectrum disorder in Hong Kong, Clinical and Translational Medicine. 2016, 5.


Researcher : Tang WF

List of Research Outputs

Chu W.Y., LEUNG K.C., Mak A.S.L., Chiu T.A., MAK C.C.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong V.C.N., Lee S.L., Marshall C., Scherer S., Kan S.Y.A. and Chung B.H.Y., Use of clinical chromosomal microarray in Hong Kong Chinese patients with autism spectrum disorder - Implication of a copy number variation involving DPP10, Asian Society for Pediatric Research (ASPR) and Faculty of Medicine Ramathibodi Hospital 2016, Thailand, Bangkok, 10-12 November 2016.
Siu C.W.K., Lam C.W., Mak C.M., Lau E.T.K., Tang M.H.Y., Tang W.F., Poon-Mak R.S., Lee C.C., Hung S.F., Leung P.W., Kwong K.L., Yau E.K., Ng G.S., Fong N.C. and Chan K.Y., Diagnostic yield of array CGH in patients with autism spectrum disorder in Hong Kong, Clinical and Translational Medicine. 2016, 5.


Researcher : Tse KY

List of Research Outputs

Cheung V.Y.T. and Tse K.Y., Vulval Hemangioma, Journal of Obstetrics and Gynaecology Canada. 2017.
Chow K.L., Tse K.Y., Cheung C.L., Wong K.W., Cheung A.N.Y., Wong W.C., Chan A.N.H., Yuen N.W.F., Ngan H.Y.S. and Ip P.C.P., The mitosis-specific marker phosphohistone-H3 (PHH3) is an independent prognosticator in uterine smooth muscle tumours: an outcome-based study, Histopathology. United Kingdom, Wiley, 2017, 70: 746-755.
Ngu S.F., Wei N., Kwan T.T., Chu M.Y.M., Tse K.Y., Chan K.K.L. and Ngan H.Y.S., Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial., J Psychosom Obstet Gynaecol. 2017.
Tse K.Y., Cheung V.Y.T., Lam C.W., Lee E.Y.P., Ngan H.Y.S. and Khong P.L., Successful Treatment of a Pararenal Pregnancy Using High-Dose Methotrexate Regimen A Case Report, Journal of Reproductive Medicine. United States, Journal of Reproductive Medicine, Inc., 2016, 61 issue 11-12: 592-594.


Researcher : WANG J

List of Research Outputs

JIANG Y., Siu K.Y., WANG J., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., Hexokinase II (HK2) regulates stemness of ovarian cancer cells, AACR Annual Meeting 2017.
WANG J., Siu K.Y., JIANG Y., Leung T.H.Y., Ngan H.Y.S., Cheung A.N.Y. and Chan K.K.L., PFKP and PFKFB3 modulate cancer metabolic switch and chemoresistance to cisplatin in ovarian cancer, AACR Annual Meeting 2017.


Researcher : WANG Z

List of Research Outputs

WANG Z., KOTTAWATTA K.S.A., Kodithuwakku S.P. and Lee C.K.F., The effect of Mancozeb on ER and Wnt/β-catenin pathway during embryo implantation in vitro cell model. P15, The Hong Kong Society of Endocrinology, Metabolism and Reproduction 33rd Annual Scientific Meeting, 20 Nov, 2016, Hong Kong. 2016.
WANG Z., KOTTAWATTA K.S.A., Kodithuwakku S.P. and Lee C.K.F., The mechanistic action of fungicide Mancozeb in suppressing spheroids attachment onto Endometrial epithelial cells. P-03, HKU-QMH Assisted Reproduction Programme, 30th Anniversary Celebration Symposium. 10-13, Nov, 2016, Hong Kong and Shenzhen. 2016.


Researcher : Wai KOJ

List of Research Outputs

Wai K.O.J. and Cheung V.Y.T., The Uterine-shaped Intrauterine Device, Journal of Obstetrics and Gynaecology Canada. 2017.


Researcher : Wei N

List of Research Outputs

Liu S., Chu K.H., Wei N., Lau S.K., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., Circulating micro-RNAs as biomarkers for detection of cervical cancer, International Papillomavirus Conference. 2017.
Ngu S.F., Wei N., Kwan T.T., Chu M.Y.M., Tse K.Y., Chan K.K.L. and Ngan H.Y.S., Impact of different educational interventions on psychosocial well-being of women with a positive high-risk human papillomavirus and normal cervical cytology: a randomised trial., J Psychosom Obstet Gynaecol. 2017.


Researcher : Wong CW

List of Research Outputs

Wong C.W., Lam K.W., Lee C.L., Yeung W.S.B., Zhao W.E., Ho P.C., Oue J.P. and Chiu C.N., The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa-zona pellucida binding, Human Reproduction. 2017, 32: 733-742.


Researcher : XU S

List of Research Outputs

XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Characterization of Endometrial Mesenchymal-like Stem Cells Activity in Different Endometrial Layers and During the Menstrual Cycle, 49th Society for the Study of Reproduction. 2016.
Xu S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle, Experimental Cell Research. Elsevier Inc, 2017, 350(1): 184-189.


Researcher : Xu S

List of Research Outputs

XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Characterization of Endometrial Mesenchymal-like Stem Cells Activity in Different Endometrial Layers and During the Menstrual Cycle, 49th Society for the Study of Reproduction. 2016.
Xu S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle, Experimental Cell Research. Elsevier Inc, 2017, 350(1): 184-189.


Researcher : YUNG MH

List of Research Outputs

Chan D.W., Yung M.H., Hardie D.G. and Ngan H.Y.S., AMP-activated protein kinase gamma-2 (AMPK-g2) subunit modulates AMPK activities to ensure ovarian cancer progression, AMPK 2016: NEW MECHANISMS and PHYSIOLOGY, November 11-16, 2016, Xiamen, China. 2016.
Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-b/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.
LIANG R., Yung M.H., Ngan H.Y.S. and Chan D.W., BCL2A1 plays a biphasic role in ovarian cancer progression: promoting cell survival and inhibiting cell proliferation, Cold Spring Harbour Asia: Cancer & Metabolism. Suzhou Dushu Lake Conference Center, Suzhou, PR China, 19 to 23rd, Sept., 2016.. 2016.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.
YUNG M.H., ROSS F.A., HARDIE D.G., ZHAN J.B., Ngan H.Y.S. and Chan D.W., Bitter melon (Momordica charantia) extract functions as a natural AMPK activator and synergistically enhances cisplatin cytotoxicity in ovarian cancer cells, Integrat Cancer Ther. 2016, 15(3): 376-89.
Yung M.H., Ngan H.Y.S., Hardie D.G. and Chan D.W., Functional characterization of MAP30 protein from bitter melon (Momordica charantia) in combating ovarian cancer oncogenesis and chemoresistance, AMPK 2016: NEW MECHANISMS AND PHYSIOLOGY (The 9thInternational Symposium on AMP-activated Protein Kinase) Nov. 11-16, 2016, Xiamen, China. 2016.
Yung M.H., Ngan H.Y.S. and Chan D.W., Identification of MAP30 as a natural AMPK activator in targeting the tumorigenicity and chemoresistance of ovarian cancer cells, CSH Asia Conference on Cancer & Metabolism. 2016.


Researcher : Yeung TWY

List of Research Outputs

Li R.H.W., Yeung T.W.Y., Lee V.C.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Comparing the inter-cycle variation of serum anti-Mullerian hormone and antral follicle count measurements in predicting ovarian response before IVF, 32nd Annual Meeting, European Society of Human Reproduction and Embryology. 2016.


Researcher : Yeung WSB

Project Title:MicroRNA-135a transforms normal HPV infected cervical cells into cancer cells and cells with cancer stem cell-like properties
Investigator(s):Yeung WSB, Tsao GSW, Ngan HYS, Pang TKR, Cheung ANY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2014


Project Title:The conserved functions of let-7 in embryonic diapause
Investigator(s):Yeung WSB, Liu W, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2015


Project Title:A study on the effect of targeted DNA methylation of PDX-1 on pancreatic lineage differentiation of human embryonic stem cells
Investigator(s):Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2015
Completion Date:06/2017


Project Title:Polyamine/Let-7 signaling in embryo implantation and diapause
Investigator(s):Yeung WSB, Lee CKF, Liu W
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


List of Research Outputs

Chan R.W.S., Lee C.L., Ng E.H.Y. and Yeung W.S.B., Co-culture with macrophages enhances the clonogenic and invasion activity of endometriotic stromal cells, Cell Proliferation. John Wiley & Sons Ltd, 2017, 50: 1-9.
Chen C.H., Lee C.Y.L., Fong S.W., Wong C.C.Y., Ng E.H.Y. and Yeung W.S.B., Hyperglycemia impedes definitive endoderm differentiation of human embryonic stem cells by modulating histone methylation patterns, Cell and Tissue Research. 2017, 2017 Jun;368(3):563-578.
Cheng H.C., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., The role of myometrium in maintaining the endometrial mesenchymal-like stem cells through secretion of matrix metalloproteinase 3, Hong Kong Society of Endocrinology Metabolism & Reproduction, Hong Kong, 20th Nov 2016. Abstract P-03: p 17.
FAN H., Yeung W.S.B. and Lee C.K.F., Bisphenol aA analogues: effect on gene activation and spheroid attachment in endometrial epithelial iIshikawa cells, 33th Annual Scientific Meeting of Hong Kong society of Endocrinology, Metabolism and Reproduction. Hong Kong, China. 2016.
FAN H., Yeung W.S.B. and Lee C.K.F., Effect of bisphenol aA analogues on gene regulation and spheroid attachment in endometrial epithelial iIshikawa cells, 21st Research Postgraduate Symposium, LKS Faculty of Medicine, The University of Hong Kong. Hong Kong, China. 2016.
FAN H., Wong C.K.C., Yeung W.S.B. and Lee C.K.F., Molecular and functional approach to delineate the effect of bisphenol analogues on the receptivity of human endometrial epithelial cells, 30th Anniversary Celebration of the HKU-QMH Assisted Reproduction Programme. Shenzhen, China. 2016.
Ko K.Y.J., Chai J., Lee V.C.Y., Li R.H.W., Lau Y.L.E., Ho K.L., Tam P.C., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Sperm retrieval rate and pregnancy rate in infertile couples undergoing in-vitro fertilisation and testicular sperm extraction for non-obstructive azoospermia in Hong Kong, Hong Kong Medical Journal. 2016, 22(6): 556-562.
Lee C.L., Yeung W.S.B. and Chiu C.N., Soluble Human Leukocyte Antigen G5 Polarizes Decidual Macrophage Differentiation from Monocyte to Promotes Fetomaternal Tolerance and Placental Development, Hong Kong Society of Endocrinology, Metabolism and Reproduction - Annual Scientific Meeting. 2016.
Lee C.L., Yeung W.S.B. and Chiu C.N., Soluble Human Leukocyte Antigen G5 Polarizes Decidual Macrophage Differentiation from Monocyte to Promotes Fetomaternal Tolerance and Placental Development, Hong Kong Society of Endocrinology, Metabolism and Reproduction - Annual Scientific Meeting. 20 Nov 2016, HK. 2016.
Lee V.C.Y., Li R.H.W., Yeung W.S.B., Ho P.C. and Ng E.H.Y., A randomized double-blinded controlled trial of hCG as luteal phase support in natural cycle frozen embryo transfer, Human Reproduction. 2017, 32: 1130-1137.
Li R.H.W., Yeung T.W.Y., Lee V.C.Y., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Comparing the inter-cycle variation of serum anti-Mullerian hormone and antral follicle count measurements in predicting ovarian response before IVF, 32nd Annual Meeting, European Society of Human Reproduction and Embryology. 2016.
Li R.H.W., Cheung T.M., Yeung W.S.B. and Ng E.H.Y., Relative importance of the different components of the Bologna criteria for predicting poor ovarian response in assisted reproduction., 11th European Congress on Menopause and Andropause. 2017.
NIU Z., Pang T.K.R., Liu W. and Yeung W.S.B., Comparison and Characterization of Extracellular Vesicles isolated from endometrial cell lines by different methodologies, SSR 49th Annual Meeting - Society for the Study of Reproduction. 2016, 210.
Wong C.W., Lam K.W., Lee C.L., Yeung W.S.B., Zhao W.E., Ho P.C., Oue J.P. and Chiu C.N., The roles of protein disulphide isomerase family A, member 3 (ERp57) and surface thiol/disulphide exchange in human spermatozoa-zona pellucida binding, Human Reproduction. 2017, 32: 733-742.
XU S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Characterization of Endometrial Mesenchymal-like Stem Cells Activity in Different Endometrial Layers and During the Menstrual Cycle, 49th Society for the Study of Reproduction. 2016.
Xu S., Chan R.W.S., Ng E.H.Y. and Yeung W.S.B., Spatial and temporal characterization of endometrial mesenchymal stem-like cells activity during the menstrual cycle, Experimental Cell Research. Elsevier Inc, 2017, 350(1): 184-189.


Researcher : Yung MH

Project Title:CSHA Meeting - Cancer and Metabolism ; Identification of MAP30 as a natural AMPK activator in targeting the tumorigenicity and chemoresistance of ovarian cancer cells
Investigator(s):Yung MH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2016
Completion Date:09/2016


List of Research Outputs

Chan D.W., Yung M.H., Hardie D.G. and Ngan H.Y.S., AMP-activated protein kinase gamma-2 (AMPK-g2) subunit modulates AMPK activities to ensure ovarian cancer progression, AMPK 2016: NEW MECHANISMS and PHYSIOLOGY, November 11-16, 2016, Xiamen, China. 2016.
Chan D.W., Hui W.W., Wang J.J., Yung M.H., Hui M.N., Qin Y.I.M.I.N.G., LIANG R., Leung T.H.Y., Xu D., Chan K.K.L., Yao K.M., Tsang B.K. and Ngan H.Y.S., DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-b/SMAD4 signaling, In: Drs. Douglas Green and Justin Stebbing , Oncogene. UK, Macmillan Publishers Limited, 2016, 36: 1404-1416.
LIANG R., Yung M.H., Ngan H.Y.S. and Chan D.W., BCL2A1 plays a biphasic role in ovarian cancer progression: promoting cell survival and inhibiting cell proliferation, Cold Spring Harbour Asia: Cancer & Metabolism. Suzhou Dushu Lake Conference Center, Suzhou, PR China, 19 to 23rd, Sept., 2016.. 2016.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Liu S., QIN Y., Lee C.K.F., Chan K.K.L., Ngan H.Y.S. and Chan D.W., Dysregulation of miR-141/KLF12/Sp1/surviving signaling promotes anoikis resistance in ovarian cancer metastatic progression, Molecular Cancer. 2017.
MAK S.L., Yung M.H., Hui M.N., LEUNG L.L., LIANG R., CHEN K., Leung T.H.Y., Chan K.K.L., Ngan H.Y.S. and Chan D.W., MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis, Molecular cancer. 2017.
YUNG M.H., ROSS F.A., HARDIE D.G., ZHAN J.B., Ngan H.Y.S. and Chan D.W., Bitter melon (Momordica charantia) extract functions as a natural AMPK activator and synergistically enhances cisplatin cytotoxicity in ovarian cancer cells, Integrat Cancer Ther. 2016, 15(3): 376-89.
Yung M.H., Ngan H.Y.S., Hardie D.G. and Chan D.W., Functional characterization of MAP30 protein from bitter melon (Momordica charantia) in combating ovarian cancer oncogenesis and chemoresistance, AMPK 2016: NEW MECHANISMS AND PHYSIOLOGY (The 9thInternational Symposium on AMP-activated Protein Kinase) Nov. 11-16, 2016, Xiamen, China. 2016.
Yung M.H., Ngan H.Y.S. and Chan D.W., Identification of MAP30 as a natural AMPK activator in targeting the tumorigenicity and chemoresistance of ovarian cancer cells, CSH Asia Conference on Cancer & Metabolism. 2016.


Researcher : Yung SF

Project Title:Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps
Investigator(s):Yung SFS, Lee CKF, Ng EHY, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2013


List of Research Outputs

Chan M.K.D., Cheung K.W., Yung S.F., Lee V.C.Y., Li R.H.W. and Ng E.H.Y., A randomized double-blind controlled trial of the use of dydrogesterone in women with threatened miscarriage in the first trimester: study protocol for a randomized controlled trial, Trials. 2016, 17.


Researcher : Yung SFS

Project Title:Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps
Investigator(s):Yung SFS, Lee CKF, Ng EHY, Yeung WSB, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2013


List of Research Outputs

Yung S.F.S., Cheng M.C.M., Ma W.S.P. and Ho P.C., Candida glabrata chorioamnionitis and fungaemia complicating pregnancy following intrauterine insemination: Case report and review of the literature, 25th Asian & Oceanic Congress of Obstetrics and Gynaecology (AOCOG) 2017 (The Journal of Obstetrics and Gynaecology Research). Wiley, 2017, 43, Issue Supplement S1: 140.


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