LKS MEDICAL FACULTY
| Researcher : Boheler KR |
| Project Title: | Cell surface glycoprotein to characterize and isolate “homogeneous” human pluripotent stem cell-derived retinal pigmented epithelial cells with enhanced therapeutic potential |
| Investigator(s): | Boheler KR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 09/2014 |
| Project Title: | Mechanistic Study of Vascular Ehlers-Danlos Syndrome using Induced Pluripotent Stem Cells derived from Humans with COL3A1 Mutations |
| Investigator(s): | Boheler KR, Li RA, Chan CWY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2014 |
| Project Title: | Advancing cell-based therapies for Parkinson's through Surfaceome Analyses |
| Investigator(s): | Boheler KR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | SFC / RGC Joint Research Scheme |
| Start Date: | 11/2014 |
| Project Title: | Establishing an internationally competitive Stem Cell Biotech Cluster in HK: Bioartificial Human Hearts |
| Investigator(s): | Boheler KR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 2) |
| Start Date: | 01/2015 |
| Project Title: | Establishing an Internationally Competitive Stem Cell Biotech Cluster in HK: Bioartificial Human Hearts |
| Investigator(s): | Boheler KR, Li RA |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2015 |
| Project Title: | STF31 and the Selective Ablation of Tumorigenic Human Pluripotent Stem Cells from Differentiated Cells Destined for Regenerative Medicine |
| Investigator(s): | Boheler KR, Wong DSH |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| List of Research Outputs |
| Guan D., Boheler K.R., Wang J.J. and Yan B., PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data, Nucleic Acids Research. UK, Oxford Journal, 2014, 12: W131-136. |
| Researcher : Chan KKK |
| List of Research Outputs |
| Cui G.Z., Luk C.W.S., Li R.A., Chan K.K.K., Lei S.W., Wang L., Shen H.F., Leung G.P.H. and Lee S.M.Y., Cytoprotection of Baicalein Against Oxidative Stress-induced Cardiomyocytes Injury Through the Nrf2/Keap1 Pathway, Journal of Cardiovascular Pharmacology. 2015, 65: 39-46. |
| Researcher : Chen JHK |
| Project Title: | Molecular epidemiology study of HIV-1 among the men who have sex with men (MSM) population in Hong Kong |
| Investigator(s): | Chen JHK, Yam WC |
| Department: | Microbiology |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 04/2009 |
| List of Research Outputs |
| Cheng V.C.C., Tai J.W., Lee W.M., Chan W.M., Wong S.C.Y., Chen J.H.K., Poon W.S.R., To K.K.W., Chan J.F.W., Ho P.L., Chan K.H. and Yuen K.Y., Infection Control Preparedness for Human Infection With Influenza A H7N9 in Hong Kong, Infection Control & Hospital Epidemiology. 2015, 36: 87-92. |
| Researcher : Chen Z |
| Project Title: | A novel model for the study of lung pathogenesis of SARS |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | National Institutes of Health, US Department of Health and Human Services - General Award |
| Start Date: | 08/2007 |
| Project Title: | Understanding the Ongoing HIV Epidemic in Yunnan China |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | China AIDS Initiative - General Award |
| Start Date: | 05/2008 |
| Project Title: | Preventing HIV-1 infection using a novel vaccine immunogen |
| Investigator(s): | Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Global Health Grants |
| Start Date: | 10/2008 |
| Project Title: | Establishment of a rapid, high-throughput, cost-effective HIV-1 drug resistance testing system |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 05/2011 |
| Project Title: | A Novel Vaccine for Mesothelioma Immunotherapy and Prevention; |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Pneumoconiosis Compensation Fund Board - General Award |
| Start Date: | 07/2011 |
| Project Title: | A promising mucosal prime and intramuscular boost AIDS vaccine regimen |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2011 |
| Completion Date: | 08/2014 |
| Project Title: | AIDS Vaccine 2011 A Novel Vaccine Design for Inducing Robust HIV-1 Specific Immunity |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2011 |
| Project Title: | Blocking HIV infection by gene-encoding neutralizing antibodies |
| Investigator(s): | Chen Z, Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2012 |
| Project Title: | AIDS Vaccine 2012; Mucosal Prime with a Replicating Vaccinia-based Vaccine Promotes Mucosal Immunity against SIV. |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2012 |
| Project Title: | Mechanism of a soluble PD-1-based vaccine in amplifying antiviral CD8+ T-cell immunity |
| Investigator(s): | Chen Z, Liu L |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Novel Secretory Immunoadhesins for HIV Prevention |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Project Title: | To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System |
| Investigator(s): | Chen Z, Liu L, Cheung KW, Du DY |
| Department: | Microbiology |
| Source(s) of Funding: | Guangdong-Hong Kong Technology Cooperation Funding Scheme |
| Start Date: | 07/2013 |
| Project Title: | Further optimization of live viral vector for HIV vaccine research |
| Investigator(s): | Chen Z, Wang H |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 11/2013 |
| Project Title: | To Establish a Novel and Rapid Phenotypic HIV-1 Drug Resistance Testing System |
| Investigator(s): | Chen Z, Liu L, Cheung KW, Du DY |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 12/2013 |
| Project Title: | Mechanism of potentiating HIV antigen-specific CD8+ T cells |
| Investigator(s): | Chen Z, Liu L, Yam WC, Cheung KLA, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Collaborative Research Fund (CRF) - Group Research Project |
| Start Date: | 06/2014 |
| Project Title: | A New Therapeutic Vaccine for HIV/AIDS |
| Investigator(s): | Chen Z, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Support Programme (Tier 3) |
| Start Date: | 12/2014 |
| Project Title: | Role of a newly identified PD-1 isoform in modulating immune responses |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | A New Therapeutic Vaccine for HIV/AIDS |
| Investigator(s): | Chen Z, Cheung KW |
| Department: | Microbiology |
| Source(s) of Funding: | Innovation and Technology Fund Internship Programme |
| Start Date: | 03/2015 |
| Project Title: | A novel PDI DNA-based vaccination strategy to mimic Gag-specific responses found in HIV Elite controllers |
| Investigator(s): | Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | ANR / RGC Joint Research Scheme |
| Start Date: | 04/2015 |
| Project Title: | Role of Δ42PD1 in HIV Infection |
| Investigator(s): | Chen Z, Cheung KLA |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2015 |
| Researcher : Cheng L |
| List of Research Outputs |
| GUO J., Zuo T., Cheng L., WU X., TANG J., Sun C.J., Feng L., Chen L., Zhang L.Q. and Chen Z., Simian Immunodeficiency Virus Infection Evades Vaccine-Elicited Antibody Responses to V2 Region, JAIDS Journal of Acquired Immune Deficiency Syndromes. 2015, 68: 502-510. |
| Researcher : Cheung KLA |
| Project Title: | Human cytomegalovirus and human immunodeficiency virus type 1 co-infection of CD34+ Myeloid Progenitor Cells |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2013 |
| Project Title: | Transfer of HIV-1 from HIV-1 latently infected CD34+ hematopoietic progenitors to CD4+ T cells |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | Downstream signaling pathways involved in Δ42PD1 cytokine induction |
| Investigator(s): | Cheung KLA, Chen Z |
| Department: | Microbiology |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2015 |
| Researcher : Cheung KW |
| Project Title: | Type of cell death and related mechanisms for gut homing CD4 T cells during human immunodeficiency virus-1 (HIV-1) infection |
| Investigator(s): | Cheung KW, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2013 |
| Project Title: | Role of microvesicles released by HIV-1 infected gut homing CD4 T cells in AIDS pathogenesis |
| Investigator(s): | Cheung KW, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Researcher : Guo J |
| List of Research Outputs |
| Shao Y., Lo C.M., Ling C., Liu X., Ng K.T.P., Guo J., Ma Y.Y., Li C., Fan S.T. and Man K., The role of regulatory B cells on hepatocellular carcinoma progression, the 21st Hong Kong International Cancer Congress. 2014. |
| Researcher : He M |
| Project Title: | Regulation of ion channels by angiotensin II in human cardiac fibroblasts |
| Investigator(s): | He M, Li GR |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2009 |
| Researcher : Ho PC |
| List of Research Outputs |
| Chai J., Lee V.C., Yeung T.W., Li R.H.W., Ho P.C. and Ng E.H.Y., Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment, PLoS One. 2015, 10(3). |
| Yeung T.W., Chai J., Li R.H.W., Lee V.C., Ho P.C. and Ng E.H.Y., The effect of endometrial injury on ongoing pregnancy rate in unselected subfertile women undergoing in vitro fertilization: a randomized controlled trial, Human Reproduction. 2014, 29: 2474-2481. |
| Researcher : Hui EC |
| Project Title: | Promotion of the reflection, dialogue and teaching of ethical issues related to the development and uses of biotechnologies among students and faculty members of health-related sciences at the University of Hong Kong |
| Investigator(s): | Hui EC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Teaching Development Grants |
| Start Date: | 03/2005 |
| Researcher : Kong MCW |
| List of Research Outputs |
| Weng J.Z., Kong M.C.W., Ren L., Karakikes I., Geng L., HE J., Chow M.Z.Y., Mok C.F., Keung W.W.Y., Chow C.H., Leung A.Y.H., Hajjar R.J., Li R.A. and Chan C.W.Y., A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells. PMID: 24564569 , Stem Cells & Development. 2014, 23(14): 1704-16. |
| Researcher : Lai WWK |
| Project Title: | Open label, prospective, double arm, randomized, pilot study to evaluate the safety and efficacy of the same day administration of PDT with verteporfin and an intravitreal injection of ranibizumab vs. ranibizumab monotherapy for the treatment of subfoveal CNV secondary to neovascular age related macular degeneration in the Asian population |
| Investigator(s): | Lai WKW, Li KKW, Wong DSH, McGhee S, Lam CLK, Chan WSC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Pharmaceutical Industry - General Award |
| Start Date: | 07/2008 |
| Project Title: | Production of Iris Pigment Epithelial Cells for transplantation to treat Age-Related Macular Degeneration |
| Investigator(s): | Lai WKW, Lo ACY, Fletcher C, Wong DSH |
| Department: | Ophthalmology |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2009 |
| Project Title: | To introduce ranibizumab (Licentis) for the treatment of diabetic macular edema to Queen Mary Hospital and to access the quality of life and utility values before and after the treatment |
| Investigator(s): | Lai WKW, Wong DSH, Li KKW |
| Department: | Ophthalmology |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 07/2010 |
| Researcher : Lam SK |
| Project Title: | Biotech Company in the Faculty of Medicine, The University of Hong Kong |
| Investigator(s): | Lam SK |
| Department: | Medicine |
| Source(s) of Funding: | The University of Hong Kong Foundation Seed Grant |
| Start Date: | 07/2003 |
| Project Title: | Treatment of gastrointestinal cancer by targeting survivin using adeno-associated virus gene delivery system |
| Investigator(s): | Lam SK, Wong BCY, Lin MC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2004 |
| Researcher : Leung GM |
| Project Title: | Evidence-based practice (EBP) learning in the undergraduate medical curriculum - where is the evidence? |
| Investigator(s): | Leung GM, Fielding R, Ho LM, Johnston JM, Lam TH |
| Department: | Community Medicine |
| Source(s) of Funding: | Leung Kau Kui Research and Teaching Endowment Fund - Teaching Grants |
| Start Date: | 01/2003 |
| Project Title: | A controlled trial of masks and hand hygiene for reducing influenza transmission |
| Investigator(s): | Leung GM, Cowling BJ, Peiris JSM, Ho LM |
| Department: | Community Medicine |
| Source(s) of Funding: | National Center for Infectious Diseases (NCID) |
| Start Date: | 09/2006 |
| List of Research Outputs |
| Cowling B.J., Perera R.A.P.M., Fang J., Chan K.H., Lim Wai S.K.W., So H.C., Chu K.W., Wong Y.T., Shiu E.Y.C., Ng S., Ip D.K.M., Peiris J.S.M. and Leung G.M., Incidence of influenza virus infections in children in Hong Kong in a 3-year randomized placebo-controlled vaccine study, 2009-2012, Clinical Infectious Diseases . 2014, 59(4): 517-24. |
| Cowling B.J., Perera R.A.P.M., Fang J., Chan K.H., Wong Y.T., Ng S., Ip D.K.M., Peiris J.S.M. and Leung G.M., Incidence of influenza virus infections in children in Hong Kong in a three year randomized placebo-controlled vaccine study (abstract & poster presentation), Influenza 2014: One Influenza, One World, One Health, 9-11 September 2014, Oxford, UK. UK, LibPubMedia Ltd, 2014. |
| Cowling B.J., Ip D.K.M., Fang J., Suntarattiwong P., Olsen S.J., Levy J., Uyeki T.M., Leung G.M., Peiris J.S.M., Chotpitayasunondh T., Nishiura H. and Simmerman J.M., Modes of Transmission of Influenza B Virus in Households, PLoS One . 2014, 9(9): e108850. |
| Cowling B.J., PARK M.A., Fang J., Wu P., Leung G.M. and Wu J.T.K., Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015, Eurosurveillance. 2015, 2015;20(25):pii=21163. |
| Cowling B.J., Peiris J.S.M. and Leung G.M., Reply to Collignon et al., Clinical Infectious Diseases. 2015, 2015;60(3): 489–90. |
| Feng L., Wu J.T.K., Liu X., Yang P., TSANG K.L., Jiang H., Wu P., Yang J., Fang J., Qin Y., Lau E.H.Y., Li M., Zheng J., Peng Z., Xie Y., Wang Q., Li Z., Leung G.M., Gao G.F., Yu H. and Cowling B.J., Clinical severity of human infections with avian influenza A(H7N9) virus, China, 2013/14, Eurosurveillance. 2014, 2014;19(49): pii=20984. |
| Ip D.K.M., Lau E.H.Y., Tam Y.H., So H.C., Lam C.K., Cowling B.J. and Leung G.M., Evaluation of an electronic smart-card based school absenteeism surveillance system , 2014 International Society for Disease Surveillance Conference, Philadelphia, USA, 9– 11 December 2014. USA, Int'l Society for Disease Surveillance. |
| Ip D.K.M., Cowling B.J., Yu H., Wu P., Lau E.H.Y. and Leung G.M., Public Health considerations for influenza A(H7N9) infection., 46th APACPH Conference, Kuala Lumpar, Malaysia, 17-19 October 2014. APACPH. |
| LEUNG Y.C., Leung G.M. and Schooling C.M., Migrant status and child and adolescent psychological well-being: evidence from Hong Kong's 'Children of 1997' birth cohort, Journal of Epidemiology and Community Health. 2015, 2015;69: 156–161. |
| Lam T.Y., Wang J., Shen Y., Zhou B., Duan L., Cheung C.L., MA C., Lycett S., Leung C.Y.H., Chen X., Li L., Hong W., CHAI Y., Zhou L., LIANG H., OU Z., Liu Y., Farooqui A., Kelvin D., Poon L.L.M., Smith D.K., Pybus O., Leung G.M., Shu Y., Webster R., Webby R., Peiris J.S.M., Rambaut A., Zhu H. and Guan Y., Research Output Prize, The University of Hong Kong. 2014. |
| Lau E.H.Y., Wu P., Wong Y.T., Wu J.T.K., Leung G.M. and Cowling B.J., Age-specific seriousness of avian influenza A(H7N9) in the second-wave epidemic in China (Poster presentation) , International Meeting on Emerging Diseases and Surveillance, Vienna, Austria, 31 October–3 November 2014. Austria, Int'l Society for Infectious Diseases. |
| Lau E.H.Y., Zheng J., TSANG K.L., Liao Q., Lewis B., Brownstein J.S., Sanders S., Mekaru S.R., Rivers C., Leung G.M., Feng L., Cowling B.J. and Yu H., Epidemiological inferences using public information, influenza H7N9 epidemic in China (Poster presentation), 2014 International Society for Disease Surveillance Conference, Philadelphia, USA, 9–11 December 2014. USA, Int'l Society for Disease Surveillance. |
| Leung G.M., "One Belt, One Road" Opportunities and Challenges for Health (Power Point Presentation), The Silk Road Economic Belt Strategy and Health Promotion Seminar of 2015, 23 May 2015, Xi'an, China. 2015. |
| Leung G.M., Challenges for Ageing and Fiscal Sustainability (Moderator), Ministerial Meeting on Universal Health Coverage The Post - 2015 Challenge, 10-11 February 2015, Singapore. 2015. |
| Leung G.M., Clinical Governance as Turnkey in HKU's Academic Medical Enterprise (powerpoint presentation), Peking University Health Forum, 4 December 2014, China . 2014. |
| Leung G.M., Collaboration Across Sector (powerpoint presentation), 1st Annual National Health Professional Education Reform Forum : ANHPERF International High Level Meeting, 17 November 2014, Thailand. 2014. |
| Leung G.M., Healthcare Policy Research: Does Hong Kong Still Aspire to Lead in Medical and Health Research? (powerpoint presentation), Health Research Symposium 2014, 15 November 2014, Hong Kong. 2014. |
| Leung G.M., Hong Kong's Experience with PPP in a Mixed Health Care Economy (PowerPoint Presentation), Public-Private Partnership (PPP) in Health Service Provision: Regulation and Financial Incentives, 12 February 2015, Seoul, Korea. 2015. |
| Leung G.M., Public Health Medicine - A Road Less Travelled (PowerPoint Presentation), 20th Hong Kong Medical Forum, Advances, Challenges and Controversies in Clinical Medicine, 16-17 May 2015, Hong Kong. 2015. |
| Ma X., Liao Q., Yuan J., Liu Y., Liu Y., Chen J., Liu J., Cai W., Cowling B.J., Di B., Fielding R., Wang M., Yang Z., Leung G.M. and Lau E.H.Y., Knowledge, attitudes and practices relating to influenza A(H7N9) risk among live poultry traders in Guangzhou City, China, BMC Infectious Diseases. 2014, 14(1): 554. |
| Schooling C.M., Au Yeung S.L.R. and Leung G.M., Why do statins reduce cardiovascular disease more than other lipid modulating therapies?, European Journal of Clinical Investigation. 2014, 2014; 44(11): 1135-40. |
| Tarrant A.M., Schooling C.M., Leung S.L.S., Mak K.H., Ho L.M. and Leung G.M., Impact of breastfeeding on infectious disease hospitalisation: the Children of 1997 cohort, Hong Kong Medical Journal. 2014, 20(S4): 5-6. |
| WANG H., Leung G.M. and Schooling C.M., Adiposity and Early Adolescent Emotional/Behavioral Problems, Journal Of Pediatrics. 2015, 2015, 166(6): 1404-9. |
| WANG H., Leung G.M. and Schooling C.M., Life Course Body Mass Index and Adolescent Self-Esteem: Evidence from Hong Kong’s “Children of 1997” Birth Cohort, Obesity (Silver Spring, Md. : Online). 2015, 2015; 23(2): 429–435. |
| Wu P., Jiang H., Wu J.T.K., Chen E., He J., Zhou H., WEI L., Yang J., YANG B., Qin Y., Fang J., Li M., TSANG K.L., Zheng J., Lau E.H.Y., Cao Y., Chai C., Zhong H., Li Z., Leung G.M., Feng L., Gao G.F., Cowling B.J. and Yu H., Poultry Market Closures and Human Infection with Influenza A(H7N9) Virus, China, 2013-14, Emerging Infectious Diseases . 2014, 20(11): 1891-4. |
| Xu C., Perera R.A.P.M., Chan Y.H., Fang J., Ng S., Ip D.K.M., Kam A.M., Leung G.M., Peiris J.S.M. and Cowling B.J., Determinants of serum 25-hydroxyvitamin D in Hong Kong., Br J Nutr.. 2015, 8: 1-8. |
| Xu C., Perera R.A.P.M., Chan Y.H., Fang J., Ng S., Ip D.K.M., Kam M.S., Leung G.M., Peiris J.S.M. and Cowling B.J., Determinants of serum 25-hydroxyvitamin D in Hong Kong, British journal of nutrition . 2015, 2015 Jul;114(1): 144-51. |
| Researcher : Li G |
| Project Title: | The 10th International Conference on Alzheimer's Disease and Related Disorders High Field MRI Study of the Beta Amyloid and Plaque Desposits in the Brain of APP/PS1 Mice CoQ10 Delays the Brain Atrophy in Transgenic Aged Mice: in Vivo Volume MRI Study |
| Investigator(s): | Li G |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2006 |
| Project Title: | Effect of imbalance of kinases and protein phosphatases on deposit of B amyloid and Tau Pathology in double transgenic APP/PS1 Mice |
| Investigator(s): | Li G, Yang X, Yang ES |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Germany/Hong Kong Joint Research Scheme |
| Start Date: | 01/2007 |
| Researcher : Li RA |
| Project Title: | Cell-based Heart Regeneration |
| Investigator(s): | Li RA, Boheler KR, Chan BP, Chan CWY, Chan GCF, Chien KR, Lee HC, Yue J, Ng RK, Ngan AHW |
| Department: | Medicine |
| Source(s) of Funding: | Theme-based Research Scheme |
| Start Date: | 09/2011 |
| Project Title: | Human WT1 epicardial progenitor cells |
| Investigator(s): | Li RA |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Stem Cell and Regenerative Medicine |
| Investigator(s): | Li RA, Chan GCF, Tse HF |
| Department: | Physiology |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 06/2013 |
| Project Title: | Engineering Calcium Homeostasis of hESC-derived cardiomyocytes |
| Investigator(s): | Li RA |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2013 |
| Project Title: | Ontogenic combinatorial conditioning of 3D human pluripotent stem cell ventricular models for facilitated maturation |
| Investigator(s): | Li RA |
| Department: | Physiology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2014 |
| Project Title: | International Society for Stem Cell Research 2015 Annual meeting; IMMUNOSUPPRESSIVE EFFECTS OF HUMAN PLURIPOTENT STEM CELL – DERIVED VENTRICULAR CARDIOMYOCYTES TOWARD HUMAN DENDRITIC CELLS |
| Investigator(s): | Li RA |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2015 |
| List of Research Outputs |
| CHEN G., LI S., Karakikes I., Ren L., Chow M.Z.Y., Chopra A., Keung W.W.Y., Yan B., Chan C.W.Y., Costa K.D., Kong M.C.W., Hajjar R.J., Chen C.S. and Li R.A., Phospholamban as a Crucial Determinant of the Inotropic Response of Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes and Engineered 3D Tissue Constructs, Circulation: Arrhythmia and Electrophysiology. 2014. |
| Cui G.Z., Luk C.W.S., Li R.A., Chan K.K.K., Lei S.W., Wang L., Shen H.F., Leung G.P.H. and Lee S.M.Y., Cytoprotection of Baicalein Against Oxidative Stress-induced Cardiomyocytes Injury Through the Nrf2/Keap1 Pathway, Journal of Cardiovascular Pharmacology. 2015, 65: 39-46. |
| Weng J.Z., Kong M.C.W., Ren L., Karakikes I., Geng L., HE J., Chow M.Z.Y., Mok C.F., Keung W.W.Y., Chow C.H., Leung A.Y.H., Hajjar R.J., Li R.A. and Chan C.W.Y., A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells. PMID: 24564569 , Stem Cells & Development. 2014, 23(14): 1704-16. |
| Zhang P., Ma Y., Wang Y., Ma X.L., Huang Y., Li R.A., Wan S. and Yao X., Nitric oxide and protein kinase G act on TRPC1 to inhibit 11,12-EET-induced vascular relaxation. PMID: 25139746 , Cardiovascular Research. 2014, 104 (1): 138-46. |
| Researcher : Liu L |
| Project Title: | Early HIV-1 diagnosis using in-house real-time PCR amplification on dried blood spots for men who have sex with men in Hong Kong |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Council for the AIDS Trust Fund - General Award |
| Start Date: | 09/2009 |
| Project Title: | Identification of small molecule HIV-1 inhibitors with distinct new targets |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 02/2012 |
| Project Title: | The role of HIV-1/SIV Nef in immune activation through regulating the expression of PD-1 and delta-PD-1 |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 03/2012 |
| Project Title: | Molecular mechanisms of Nef mediated regulation of PD-1 expression during HIV/SIV infection |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | A novel small molecule from natural product as a potential agent for purging HIV-1 from the latent reservoir |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2014 |
| Project Title: | AIDS 2014; Community-based HIV-1 Early Diagnosis and Risk Behavior Analysis of Men Having Sex with Men in Hong Kong |
| Investigator(s): | Liu L |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2014 |
| Completion Date: | 07/2014 |
| Project Title: | Defining the role of monocyte-derived dendritic cells in potentiating durable and protective T-cell immunity by a newly identified PD-1 isoform |
| Investigator(s): | Liu L, Chen Z |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| List of Research Outputs |
| Liu L., Liang J., Cheung M., Lee M. and Chen Z., Community-based HIV-1 Early Diagnosis and Risk Behavior Analysis of Men Having Sex with Men in Hong Kong. , 20th International AIDS Conference . 2014. |
| Liu L., Early events of SARS-CoV infection in Chinese macaques, University of Adelaide Discipline of Surgery (TQEH), Adelaide, Australia. 2014. |
| Researcher : Lok S |
| Project Title: | Generation of ferret (Mustela putorius furo) genomic resources for respiratory infectious disease research: Transcriptomics and comprehensive characterization of cDNAs in a model of influenza infection |
| Investigator(s): | Lok S, Tong AHY, Lee MY |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 04/2011 |
| Researcher : Rong J |
| Project Title: | The 7th International Conference on Systems Biology Genome-wide Biological Response Fingerprinting (BioReF) of Traditional Chinese Medicine Formula ISF-1 Reveals a Potential Role of Heme Oxygenase-1 Pathway in the Antioxidant Therapy |
| Investigator(s): | Rong J |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2006 |
| Project Title: | Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) for the resolution of neutrophil-induced myocardial injury |
| Investigator(s): | Rong J, Lau ASY, Li XC, Tse HF, Xia Z |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2012 |
| Project Title: | Biological characterization of botanical non-steroidal progesterone receptor modulator puerarin for potentiating nerve growth factor (NGF)-induced neuritogenesis |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2014 |
| Project Title: | N-Propargyl caffeamide promotes macrophage transformation from inflammatory M1 to anti-inflammatory M2 phenotypes in the context of myocardial infarction |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2015 |
| Project Title: | The XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function and the XIIth International Conference on Quantification of Brain Function with PET ; Plant natural product puerarin suppressed 6-hydroxydopamine (6-OHDA)-induced neurotoxicity via inducing mitochondrial enzyme arginase-2 |
| Investigator(s): | Rong J |
| Department: | School of Chinese Medicine |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2015 |
| Researcher : Sham PC |
| Project Title: | Replication study of susceptibility genes for colorectal cancer |
| Investigator(s): | Sham PC, Ho JWC, Cheng KK |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 10/2007 |
| Project Title: | Partner State Key Laboratory of Brain and Cognitive Sciences |
| Investigator(s): | Sham PC, So KF, Tan L |
| Department: | Centre for Genomic Sciences |
| Source(s) of Funding: | Matching Fund for State Key Laboratory (SKL) |
| Start Date: | 10/2008 |
| Project Title: | Visiting Research Professors Scheme 2009-10 |
| Investigator(s): | Sham PC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Visiting Research Professors Scheme |
| Start Date: | 09/2009 |
| Project Title: | To determine the functional variants of candidate genes identified by Genome-wide Association Study of Osteoporosis |
| Investigator(s): | Sham PC, Gao RY, Xiao S, Kung AWC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 07/2010 |
| Project Title: | Method and Software for Personal Risk Profiling of Complex Diseases |
| Investigator(s): | Sham PC, Cherny SS, Garcia-Barcelo MM, Kung AWC, Li M, Yang W |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2012 |
| Project Title: | Bioinformatics tools for identifying disease loci from exome sequencing data |
| Investigator(s): | Sham PC, Cherny SS, Garcia-Barcelo MM, Li M, Yang W |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2013 |
| Project Title: | Genomics |
| Investigator(s): | Sham PC, Chin FYL, Leung FCC |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 06/2013 |
| Project Title: | Cross Cultural Differences in Biased Cognition |
| Investigator(s): | Sham PC, Chen EYH, Toulopoulou T |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | ESRC/RGC Joint Research Scheme |
| Start Date: | 09/2013 |
| Project Title: | Statistical methods for characterizing the genetic component of polygenic diseases |
| Investigator(s): | Sham PC, Cherny SS |
| Department: | Psychiatry |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Project Title: | Mutational spectrum for dilated cardiomyopathy in Hong Kong |
| Investigator(s): | Sham PC, Tse HF, Cherny SS, Garcia-Barcelo MM, Tang SM, Li M |
| Department: | Centre for Genomic Sciences |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 04/2014 |
| Project Title: | Schizophrenia-related de novo and compound heterozygous mutations |
| Investigator(s): | Sham PC, Chen EYH, Chang WC, Chan KW, Lee HME, Cherny SS, Li M |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2015 |
| List of Research Outputs |
| Cheng J., Zhou X., Lu Y., Chen J., Han B., Zhu Y., Liu Y., Choy K.W., Sham P.C., Zhang M.Q., Zhang X. and Yuan H., Exome Sequencing Identifies a Novel Frameshift Mutation of MYO6 as the Cause of Autosomal Dominant Nonsyndromic Hearing Loss in a Chinese Family, In: Mark G. Thomas, Annals of Human Genetics. Wiely, 2014, 78: 410-423. |
| Li Q., Chan K.W., Sun L.I.N., Chan W.C., Chen E.Y.H. and Sham P.C., Imaging the effects of ketamine use and abuse in the brain, In: David Yew, Ketamine: Use and Abuse. CRC Press, 2015, 145-172. |
| Researcher : Sun W |
| List of Research Outputs |
| Sun W., Yang L.H., Lau A.S.Y. and Li C.B., Inhibitory Effect of Panax Notoginseng (PNG) Extracts on the TNF-α-induced MMP-9 Activity in Cardiomyoblasts, 2014 Annual Scientific Meeting, Hong Kong College of Paediatricians. 2014. |
| Researcher : Wong DSH |
| Project Title: | To introduce bevacizumab for the treatment of macular degeneration and diabetic retinopathy to Queen Mary Hospital |
| Investigator(s): | Wong DSH, Lai WKW, Li KKW |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 03/2008 |
| Project Title: | The Royal College of Ophthalmologists Annual Congress 2009 Can Lutein Protect the Outer Retina? |
| Investigator(s): | Wong DSH |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2009 |
| Project Title: | Effectiveness of lens extraction with intraocular lens implantation for the treatment of primary angle closure glaucoma: A randomized controlled trial (EAGLE) |
| Investigator(s): | Wong DSH, Lai JSM |
| Department: | Ophthalmology |
| Source(s) of Funding: | Medical Research Council (MRC) - General Award |
| Start Date: | 09/2009 |
| Completion Date: | 01/2015 |
| Project Title: | XXVIIIth Meeting of the Club Jules Gonin WHAT IS THE MOST EFFECTIVE WAY OF PREVENTING EMULSIFICATION OF SILICONE OIL |
| Investigator(s): | Wong DSH |
| Department: | Ophthalmology |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2012 |
| Project Title: | Neuroscience |
| Investigator(s): | Wong DSH, Lee TMC |
| Department: | Ophthalmology |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 11/2013 |
| Project Title: | Randomised double-masked controlled trial of Lutein as an adjunct to surgery to improve the visual outcome of rhegmatogenous retinal detachment |
| Investigator(s): | Wong DSH, McGhee S, Lo ACY, Wong YHI |
| Department: | Ophthalmology |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2013 |
| Completion Date: | 08/2014 |
| List of Research Outputs |
| Lam H.W., Chan G.C.F., Marcet M.M., Wong W.H.S., Wong J. and Wong D.S.H., Spontaneous Self-Concept Among Chinese University Undergraduates in Hong Kong, Social Behavior and Personality. 2014. |
| Researcher : Wu HY |
| List of Research Outputs |
| Wu H.Y., World citizenship and the emergence of the social psychiatry project of the World Health Organization, 1948-c.1965, History of Psychiatry. 2015, 26: 166-181. |
| Researcher : Yau JMH |
| Project Title: | Angiopoietin-like proteins 3 and 4 as novel inhibitors of lipoprotein lipase: functional and structural studies |
| Investigator(s): | Yau JMH, Xu A, Lam KSL |
| Department: | LKS Medical Faculty |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2006 |