DEPT OF PAEDIATRICS & ADOLESCENT MED
| Researcher : CAO J |
| List of Research Outputs |
| ROBLES J.D., Liu Y., CAO J., XIANG Z. and Chan G.C.F., Immunosuppressive mechanisms of human bone marrow derived mesenchymal stromal cells in BALB/c host graft versus host disease murine models, Exp Hematol Oncol. 2015. |
| Researcher : CHEN R |
| List of Research Outputs |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Researcher : CHOI CK |
| List of Research Outputs |
| CHOI C.K., Ho D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-positive epithelial malignancies, 21st Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| CHOI C.K., Ho D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies , 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong, . 2014. |
| CHOI C.K., HO D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies, 16th International Symposium on EBV and Associated Diseases. 2014. |
| CHOI C.K., Hui K.F., Ho D.N., Kao R.Y.T. and Chiang A.K.S., Novel organic compounds for induction of lytic cycle of EBV in nasopharyngeal carcinoma, The Croucher Foundation Advanced Study Institute on Advances in Nasopharyngeal Carcinoma Studies, Hong Kong. 2014. |
| Hui K.F., CHOI C.K., YEUNG P.L., Cheung A.K., Middeldorp J.M., Lung M.L., Tsao G.S.W. and Chiang A.K.S., A potent class I histone deacetylase inhibitor romidepsin induced lytic cycle of Epstein-Barr virus (EBV) in EBV-positive epithelial malignancies, Golden Jubilee Scientific Meeting (Oral Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., CHOI C.K., YEUNG P.L., Middeldorp J.M., Tsao G.S.W. and Chiang A.K.S., Inhibition of class I Histone Deacetylases (HDACs) by HDAC inhibitors leads to the induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-positive epithelial malignancies, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., CHOI C.K., YEUNG P.L., MIDDELDORP J.M., Tsao G.S.W. and Chiang A.K.S., Inhibition of class I histone deacetylases (HDACs) by HDAC inhibitiors leads to the induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Researcher : CHONG CH |
| List of Research Outputs |
| CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., A mouse model of emotional dysregulation with deficiency in LRRC7, 19th Research Postgraduate Symposium, 10-11 December 2014. |
| CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., A mouse model of emotional dysregulation with deficiency in LRRC7, 50th Anniversary Golden Jubilee Scientific Meeting, 29-30 November 2014. |
| Researcher : Chan GCF |
| Project Title: | Treatment protocol for childhood medulloblastoma in Hong Kong |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/2001 |
| Project Title: | Review of local experience in the management of childhood myelodysplastic syndrome |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/2001 |
| Project Title: | Survey on the prevalence on use of alternative medical treatment in paediatric patients |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 09/2001 |
| Project Title: | Direct generation and functional characterization of human dendritic cells derived from bone marrow cells of leukemic origins |
| Investigator(s): | Chan GCF, Chiu CSW, Ma ESK, Huang F |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/2002 |
| Project Title: | King's/HKU Fellowship Awards 2009-10 |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | King's/HKU Fellowship Awards |
| Start Date: | 09/2009 |
| Project Title: | Molecular diagnosis for Childhood Cancers: Defining the Prognosis and Stratifying the Proper Treatments |
| Investigator(s): | Chan GCF, Tam PKH |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 01/2014 |
| Project Title: | Human Mesenchymal Stem Cells as a Therapeutic Modality for Graft Versus Host Disease Murine Models |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| List of Research Outputs |
| Chan G.C.F., Basic biology & clinical applications of mesenchymal stem cells. Karolinska Institutet - Hong Kong Stem Cells Summit, Hong Kong Stem Cells Summit. 2014. |
| Chan G.C.F., CNS Germ Cell Tumors in Children , 9th SIOP-Asia Congress, Amman, Jordan. 2015. |
| Chan G.C.F., Current management of low and intermediate risk childhood neuroblastoma, 9th Pediatric Oncology Symposium, SYS Oncology Hospital, Guangzhou , PRC. 2014. |
| Chan G.C.F., Focus on future therapies: Stem cell therapy for disease of children, 5th Mid West China Pediatric Conference, Chongqing, PRC. 2015. |
| Chan G.C.F., Novel Pediatric Therapy: Gene & Stem Cell Therapy, 50th Anniversary of the University Paediatric & Adolescent Medicine Department, Hong Kong. 2014. |
| Chan G.C.F., Novel Therapy in Paediatrics of the New Era, Private Practice Paediatrician Association Monthly Meeting, Hong Kong. 2014. |
| Chan G.C.F., Novel compound Bismuth Zinc can protect against cisplatinum induced nephrotoxicity, 6th Cross Strait Symposium on Pediatric Oncology, Taichung, Taiwan. 2014. |
| Chan G.C.F., Pre-opeative hematologic clearance, 33rd Post-Graduate Course in Pediatrics, Department of Pediatrics, University of East, Manila, Philippines. 2015. |
| Chan G.C.F., Proposal of risk stratified treatment protocol for childhood medulloblastoma, Visiting Professor Lecture, SYS University Oncology Hospital, Guangzhou, PRC. 2015. |
| Chan G.C.F., Recent advances in cellular therapy for pediatric patients, Annual National Pediatric Meeting, Chongqing, PRC. 2014. |
| Chan G.C.F., Recent advances in childhood AML & MDS, Paediatric Oncology Workshop, Wuhan Women & Children Hospital, Wuhan, PRC. 2014. |
| Chan G.C.F., Recent advances in neuroblastoma, National Cancer Congress, Jinan, PRC. 2014. |
| Chan G.C.F., Recent advances in pediatric intracranial tumors, National Pediatric Hematology Oncology Meeting, Qingdao, PRC. 2015. |
| Chan G.C.F., Recent advances in pediatric oncology: is achieving high cure rate the only concern?, 21st Hong Kong International Cancer Congress & 11th Annual Meeting of Centre for Cancer Research, Hong Kong. 2014. |
| Chan G.C.F., Recent advances in the management of pediatric cancers, 1st Hong Kong Shenzhen International Cancer Congress, Shenzhen, PRC. 2014. |
| Chan G.C.F., Stem cell therapy in pediatrics, 33rd Post-Graduate Course in Pediatrics, Department of Pediatrics, University of the East, Manila, Philippines. 2015. |
| Chan G.C.F., Targeted therapy for inherited monogenetic disease: What can we learn from the treatment of tuberous sclerosis?, Macau Central Hospital Visiting Consultant Lecture. 2014. |
| Chan G.C.F., The evolution of treatment in childhood neuroblastoma, 11th ASPR Annual Meeting, Osaka, Japan. 2015. |
| Chen M.P., Cabantchik Z.I., Chan S., Chan G.C.F., Cheung Y.F. and Obukhov A.G., Iron Overload and Apoptosis of HL-1 Cardiomyocytes: Effects of Calcium Channel Blockade, PLoS ONE. 2014, 9: e112915. |
| Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Interventions for prophylaxis of hepatic veno-occlusive disease in people undergoing heamatopoietic stem cell transplantation, Cochrane Database Systematic Review. 2015, 5: CD009311. |
| Cheuk K.L.D., Chiang A.K.S., Chan G.C.F. and Ha S.Y., Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer, Cochrane database of Systematic Reviews. 2014, CD006945. |
| Cheung Y.F., Lam W.W., Ip J.J., Cheuk D.K., Cheng F.W., Yang J.Y., Yau J.P., Ho K.K., Li C.K., Li R.C., Yuen H.L., Ling A.S., Li W.W. and Chan G.C.F., Myocardial iron load and fibrosis in long term survivors of childhood leukemia, Pediatr Blood Cancer . 2015. |
| Chu W.Y., Cheuk K.L.D., Chung B.H.Y., Bowers N.L., Ha S.Y., Chiang A.K.S. and Chan G.C.F., A patient with mosaic neurofibromatosis type 2 presenting with early onset meningioma, British Medical Journal. 2014. |
| DEE C.M.A., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Incidence of deferasirox-induced renal tubular dysfunction in children and young adults with beta-thalassemia., British Journal of Haematology. 2014, 167: 434-436. |
| HONG Y., LAI Y.T., Chan G.C.F. and Sun H., Glutathione and multidrug resistance protein transporter mediate a self-propelled disposal of bismuth in human cells, Proc Natl Acad Sci USA. 2015, 112: 3211-3216. |
| KUI L., Chan G.C.F., Lee P.P.W. and Lee P.P.W., Regulatory role of TSG-6 in TLR-9 signaling of type 1 interferon and cytokines in the innate immunity (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Lam H.W., Chan G.C.F., Marcet M.M., Wong W.H.S., Wong J. and Wong D.S.H., Spontaneous Self-Concept Among Chinese University Undergraduates in Hong Kong, Social Behavior and Personality. 2014. |
| Ling W.L., Chan G.C.F. and Li C.B., A possible role of IL-17 during Salmonella typhimurium infection, 5th International Human Microbiome Congress. 2015. |
| Liu A.P.Y., Chan G.C.F., Chung B.H.Y. and So J.C.C., Infant onset pancytopenia: A Case Report of Fanconi Anaemia managed with Matched-Sibling Cord Blood Transplantation (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Liu A.P.Y., Chang K.O., Au Yeung K.H.R., Chan A. and Chan G.C.F., Succinate Dehydrogenase Subunit B (sdhb) Gene Mutations In Paediatric Metastatic Paraganglioma: A Report Of Two Cases, Hong Kong College of Paediatricians Annual Scientific Meeting 2014. |
| ROBLES J.D., Liu Y., CAO J., XIANG Z. and Chan G.C.F., Immunosuppressive mechanisms of human bone marrow derived mesenchymal stromal cells in BALB/c host graft versus host disease murine models, Exp Hematol Oncol. 2015. |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |
| YEUNG K.S., LEUNG K.C., Wong W.L., Li R.C.H., Choi K.Y., Kuong E.Y.L., Chow W., To M., Chan G.C.F. and Chung B.H.Y., Somatic Mosicism of PIK3CA mutation In PIK3CA-related overgrowth disorders (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Researcher : Chan KW |
| List of Research Outputs |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| Researcher : Chan LY |
| List of Research Outputs |
| Chiu S.S.S., Ho P.L., Peiris J.S.M., Chan K.H. and Chan L.Y., Population-based hospitalization incidence of respiratory viruses in community-acquired pneumonia in children younger than 5 years of age, Influenza and Other Respiratory Viruses. 2014, 8(6): 626-7. |
| Chiu S.S.S., Ho P.L., Khong P.L., Ooi C.G.C., So L.Y., Wong W.H.S. and Chan L.Y., Population-based incidence of community-acquired pneumonia hospitalization in Hong Kong children younger than 5 years before universal conjugate pneumococcal immunization. , Journal of Microbiology, Immunology and Infection. 2014. |
| Cowling B.J., Chan K.H., Feng S., Chan L.Y., Lo J.Y.C., Peiris J.S.M. and Chiu S.S.S., The effectiveness of influenza vaccination in preventing hospitalizations in children in Hong Kong, 2009–2013, Vaccine. Elsevier, 2014, 32: 5278-5284. |
| Ho P.L., Chiu S.S.S., LAW Y.T., Chan L.Y., Lai E.L.Y. and Chow K.H., Increase in the nasopharyngeal carriage of non-vaccine serogroup 15 Streptococcus pneumoniae after introduction of children pneumococcal conjugate vaccination in Hong Kong, Diagnostic Microbiology and Infectious Disease. 2015, 81: 145-148. |
| Researcher : Chan SHS |
| List of Research Outputs |
| Bladen C.J., Salgado D., Monges S., Fonchuberta M.E., Kekou K., Kosma K., Dawkins H., Lamont L., Roy A., Chamova T., Guergueltcheva V., Chan S.H.S., Korngut L., Campbell C., Dai Y., Wang J., Barisic N., Barbec P., Lahdetie J., Walter M.C., Schreiber-Katz O., Karcagi V., Garami M., Viswanathan V., Bayat F., Buccella F., Kimura E., Koeks Z., van den Bergen J.C., Rodriguess M., Roxburgh R., Lusakowska A., Kostera-Pruszczyk A., Zimowski J., Santos R., Neagu E., Artemieva S., Rasic V.M., Vojinovic D., Posada M., Bloetzer C., Jeannet P.Y., Joncourt F., Diaz-Manera J., Gallardo E., Karaduman A.A., Topaloglu H., Sherif R.E., Stringer A., Shatillo A., Martin A.S., Peay H.L., Bellgard M.I., Kirschner J., Flanigan K.M., Straub V., Bushby K., Verschuuren J., Aartsma-Rus A., Beroud C. and Lochmuller H., The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations, Human Mutation. 2015, 36: 395-402. |
| Chan S.H.S., Foley A.R., Phadke R., Mathew A.A., Pitt M., Sewry C. and Muntoni F., Limb girdle muscular dystrophy due to LAMA2 mutations: diagnostic difficulties due to associated peripheral neuropathy, Neuromuscular Disorder. 2014, 24: 677-683. |
| Researcher : Chan SSK |
| List of Research Outputs |
| Chu W.Y., Chan S.S.K., Parents of Little People H.K. and Chung B.H.Y., Challenges faced by little people of Hong Kong - Narrative medicine in clinical genetics practice (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Researcher : Chan SY |
| Project Title: | Effect of the nucleosome assembly protein Tspyl2 in building the epigenetic landscape |
| Investigator(s): | Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2013 |
| Completion Date: | 05/2015 |
| Project Title: | Gene environment interaction in anxiety and aggressive behaviour |
| Investigator(s): | Chan SY, Li Q |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| Project Title: | Role of TSPYL2 in epigenetic control of gene expression |
| Investigator(s): | Chan SY, Chan KMJ |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2014 |
| Project Title: | Multiplex gene targeting of TSPYL family in embryonic stem cells |
| Investigator(s): | Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2015 |
| List of Research Outputs |
| CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., A mouse model of emotional dysregulation with deficiency in LRRC7, 19th Research Postgraduate Symposium, 10-11 December 2014. |
| CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., A mouse model of emotional dysregulation with deficiency in LRRC7, 50th Anniversary Golden Jubilee Scientific Meeting, 29-30 November 2014. |
| Chan S.Y., Facilitator, Workshop on Animal Research Ethics, 2014. |
| Liu H., SO J., TSANG K.H., Mak H.S. and Chan S.Y., A novel role of nucleosome assembly protein in histone modification, Stem Cells and Epigenetics in Cancer, HK, 16-18 October 2014. |
| Researcher : Chau AKT |
| List of Research Outputs |
| Chau A.K.T., Application of stent implantation in congenital heart disease, Chinese Medical Journal. 2014, 127(21): 3814-3824. |
| Chau A.K.T., Stenting of Coarctation of Aorta in Children, Interventional Medicine & Technology. 介入医疗与技术, 2014, 4: 20-29. |
| MAK C.C.Y., Chow P.C., Chau A.K.T., Chan Y.K., Bassett A.S. and Chung B.H.Y., Clinical implications of large rare copy number variations in 110 Chinese patients with conotruncal heart disease (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Researcher : Chau CSK |
| List of Research Outputs |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Researcher : Chee WYY |
| List of Research Outputs |
| YEUNG K.S., Chee W.Y.Y., Luk H.M., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Shuen A.Y., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Spread of X Inactivation on Chromosome 15 is Associated with a More Severe Phenotype in a Girl with an Unbalanced t(X;15) Translocation, American Journal of Medical Genetics (Part A). 2014, 164(10): 2521-2528. |
| Researcher : Chen HSR |
| List of Research Outputs |
| Li W.Y.V., Chen H.S.R., Wong W.H.S. and Cheung Y.F., Left ventricular cotractile reserve in young adults long-term after repair of coarctation of the aorta , Am J Cardiol . 2015, 115: 348-53. |
| Researcher : Cheuk KLD |
| List of Research Outputs |
| Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Interventions for prophylaxis of hepatic veno-occlusive disease in people undergoing heamatopoietic stem cell transplantation, Cochrane Database Systematic Review. 2015, 5: CD009311. |
| Cheuk K.L.D., Chiang A.K.S., Chan G.C.F. and Ha S.Y., Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer, Cochrane database of Systematic Reviews. 2014, CD006945. |
| Chu W.Y., Cheuk K.L.D., Chung B.H.Y., Bowers N.L., Ha S.Y., Chiang A.K.S. and Chan G.C.F., A patient with mosaic neurofibromatosis type 2 presenting with early onset meningioma, British Medical Journal. 2014. |
| Chua G.T., Chow K.C., So J.C.C. and Cheuk K.L.D., Aleukaemic leukaemia presenting with pathological fracture, Case Reports. 2014, 2014: bcr2014204690-bcr2014204690. |
| DEE C.M.A., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Incidence of deferasirox-induced renal tubular dysfunction in children and young adults with beta-thalassemia., British Journal of Haematology. 2014, 167: 434-436. |
| Researcher : Cheung PT |
| Project Title: | The Endocrine Society 83rd Annual Meeting Mutations of the CYP11B2 Gene in a Patient with Corticosterone Methyl Oxidase Type II Deficiency |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2001 |
| Project Title: | International Perinatal Collegium 2005 Meeting New Approaches in Old Models - Identification of Novel Molecular Alterations in Neonatal Mouse Hypoxic-Ischaemic Brain Damage |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2005 |
| Project Title: | 4th Asian Epigenomics Meeting Methyl mercury induced epigenetic dysregulation of BDNF gene in NG108 cells in vitro – a possible mechanism of environment-epigenome interactions underlying neuropsychiatric and neurodevelopmental disorders. |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 08/2009 |
| Project Title: | 9th Joint Meeting of Paediatric Endocrinology; Effective treatment with low dose dihydrotestosterone gel on three Chinese boys with 5-alpha-reductase II deficiency |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2013 |
| List of Research Outputs |
| Li R.H.W., Lam K.S.L., Tam S., Lee V.C.Y., Yeung T.W.Y., Cheung P.T., Yeung W.S.B., Ho P.C. and Ng E.H.Y., Screening for dysglycaemia by oral glucose tolerance test should be recommended in all women with polycystic ovary syndrome., Human Reproduction. 2015, 30(9): 2178-2183. |
| Researcher : Cheung TK |
| List of Research Outputs |
| Abraham A., Wong W.H.S., Lee A., Louie L.H.T., Nelson E.A.S., Ho K.W., So H.K., Wong R.S.M., Yu C., Cheung T.K., Yue S.K., Lam S.F., Chow W.C., Chow C.B. and Ip P., Promoting Physical Activity among Adolescents in Hong Kong, Hong Kong College of Paediatricans, Annual Scientific Meeting, 6 December 2014. |
| Researcher : Cheung YF |
| Project Title: | CSX/NKX2.5 mutations in patients with pulmonary atresia and intact ventricular septum |
| Investigator(s): | Cheung YF, Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Project Title: | Development of a multimedia tool for teaching of paediatric cardiology |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants |
| Start Date: | 04/2004 |
| Project Title: | Arterial-Ventriculo-Atrial Interaction in Patients After Surgical Repair of Coarctation of the Aorta |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2013 |
| Completion Date: | 11/2014 |
| Project Title: | Right and Left Atrial Function in Patients After Surgical Repair of Tetralogy of Fallot |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2014 |
| Project Title: | Circulating MicroRNAs and Myocardial Damage in Paediatric Cancer Patients Receiving Anthracyline Therapy |
| Investigator(s): | Cheung YF, Cheuk KLD, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2014 |
| Project Title: | Left Atrial Mechanics and Remodeling in Anthracycline-Treated Long-Term Survivors of Childhood Cancers |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2015 |
| Project Title: | Circulating Transforming Growth Factor-β and Aortic Dilation in Patients with Repaired Congenital Heart Disease |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2015 |
| List of Research Outputs |
| Chen M.P., Cabantchik Z.I., Chan S., Chan G.C.F., Cheung Y.F. and Obukhov A.G., Iron Overload and Apoptosis of HL-1 Cardiomyocytes: Effects of Calcium Channel Blockade, PLoS ONE. 2014, 9: e112915. |
| Cheung Y.F., Assessment of right ventriculr function in pulmonary hypertension, Updates in management of paediatric pulmonary hypertension 2014, Hong Kong Society of Paediatric Cardiology, Hong Kong. 2014. |
| Cheung Y.F., Congenital Heart Diseases: Presentations and Management in Neonates , Practical Paediatrics Update Course 2015, HKU Shenzhen Hospital, 14 March 2015. 2015. |
| Cheung Y.F., Echocardiographic evaluation of right ventricular function in congenital heart disease., Chin Med J (Engl). 2014, 127: 3789-97. |
| Cheung Y.F., Evaluation of Cardiac function, the 17th Annual Meeting of Japanese Society for Adult Congenital Heart Disease, Tokyo. 2015. |
| Cheung Y.F., Fontan post-operative management, 8th AATS/ASCVTS post graduate course, 23rd Annual Meeting of the Asian Society for Cardiovascular and Thoraic Surgery, Hong Kong. 2015. |
| Cheung Y.F., Fontan: Post-operative management , AATS / ASCVTS Hong Kong Congenital Post-graduate Course, May 2015. 2015. |
| Cheung Y.F., Lam W.W., Ip J.J., Cheuk D.K., Cheng F.W., Yang J.Y., Yau J.P., Ho K.K., Li C.K., Li R.C., Yuen H.L., Ling A.S., Li W.W. and Chan G.C.F., Myocardial iron load and fibrosis in long term survivors of childhood leukemia, Pediatr Blood Cancer . 2015. |
| Cheung Y.F., Right Ventricular Dysfunction In Congenital Heart Disease: New Insights On Pathogenesis, Assessment, And Management, 第十九次全国儿科学术大会, 2014. |
| Cheung Y.F., Roles of ECMO in pediatric heart failure , NHAM Annual Scientific Meeting 2015, Kuala Lumpur, 9 to 12 April 2015. 2015. |
| Cheung Y.F., The 5th Shanghai Symposium on Pediatric Cardiovascular Disease in Shanghai, 第五届上海国际儿科心血管疾病研讨会, Clinical Usefulness of Brain Natriuretic Peptide in Congenital Heart Disease. 2014. |
| Cheung Y.F., Timing for Pulmonary Valve Replacement , Pediatric and Adult Interventional Cardiac Symposium, Asia Pacific, Taipei, Taiwan. 2015. |
| Cheung Y.F., Understanding heart failure - back to basics, NHAM Annual Scientific Meeting 2015, Kuala Lumpur, 9 - 12 April 2015. 2015. |
| Cheung Y.F., Update on Kawasaki Disease: Diagnosis and Management, CME Lecture in Paediatrics, Canossa Hospital (Caritas) . 2015. |
| Cheung Y.F., Use of Beta Blocker in pediatric heart failure: who, when and how to give? , NHAM Annual Scientific Meeting 2015, Kuala Lumpur, 9 to 12 April 2015. 2015. |
| Cheung Y.F., Vascular health late after Kawasaki disease: implications for accelerated atherosclerosis, Korean Journal of Pediatrics. 2014, 57: 472. |
| Cheung Y.F., What happens to the right ventricle after biventricular repair for PA-IVS – presented to the Congress of Congenital Heart Disease Right Heart Interventions from A to Z, Ho Chi Minh City, Vietnam, 2015. 2015. |
| Cheung Y.F., 心功能的超聲學評價 , 第六屆中日小兒高峰論壇暨《小兒心臟電生理基礎及臨床應用進展》《川崎病診斷與治療研究新進展》學習班, 2015. |
| Li W.Y.V. and Cheung Y.F., Arterial-left ventricular-left atrial coupling late after repair of aortic coarctation and interruption , European Heart Journal - Cardiovascular Imaging . 2015, doi:10.1093/ehjci/jeu309. |
| Li W.Y.V., Chen H.S.R., Wong W.H.S. and Cheung Y.F., Left ventricular cotractile reserve in young adults long-term after repair of coarctation of the aorta , Am J Cardiol . 2015, 115: 348-53. |
| Li W.Y.V. and Cheung Y.F., Right ventricular myocardial motion and deformation in adolescents and young adults after repair of coarctation of the Aorta (doi:10.1111/echo.12868), Echocardiography. 2015, 797-804. |
| Researcher : Chiang AKS |
| Project Title: | Genetic studies of tubercubosis |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 03/2002 |
| Project Title: | Prospective study of virologic and immunologic parameters of primary Epstein-Barr virus infection in Chinese children |
| Investigator(s): | Chiang AKS, Chan KH |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2003 |
| Project Title: | Prospective study of Epstein-Barr virus (EBV) strains in primary EBV infection |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Project Title: | Longitudinal study of Epstein-Barr virus specific antibody responses in childhood infectious mononucleosis |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2005 |
| Project Title: | Investigating the function and maturation of Epstein-Barr virus (EBV)-specific T cell responses in patients with EBV-associated haemophagocytic lymphohistiocytosis |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2013 |
| Project Title: | Effects of romidepsin on induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2014 |
| Project Title: | 16th International Symposium on EBV and Associated Diseases; Emergence of highly functional antigen-specific T cells towards Epstein-Barr virus corresponds to viral control and enhanced cytotoxicity in children with infectious mononucleosis and primary asymptomatic infection/Genomic diversity of Epstein-Barr virus genomes isolated from primary nasopharyngeal carcinoma biopsies |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2014 |
| Completion Date: | 07/2014 |
| Project Title: | Delineating pathogenic mutations in Epstein-Barr virus genomes of nasopharyngeal carcinoma using next generation sequencing technology |
| Investigator(s): | Chiang AKS, Lung ML, Sham PC, Yang W, Kwong DLW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2015 |
| Project Title: | Longitudinal study of NK cell subset and function in childhood infectious mononucleosis and post-transplant lymphoproliferative disorder |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2015 |
| List of Research Outputs |
| CHOI C.K., Ho D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-positive epithelial malignancies, 21st Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| CHOI C.K., Ho D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies , 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong, . 2014. |
| CHOI C.K., HO D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies, 16th International Symposium on EBV and Associated Diseases. 2014. |
| CHOI C.K., Hui K.F., Ho D.N., Kao R.Y.T. and Chiang A.K.S., Novel organic compounds for induction of lytic cycle of EBV in nasopharyngeal carcinoma, The Croucher Foundation Advanced Study Institute on Advances in Nasopharyngeal Carcinoma Studies, Hong Kong. 2014. |
| Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Interventions for prophylaxis of hepatic veno-occlusive disease in people undergoing heamatopoietic stem cell transplantation, Cochrane Database Systematic Review. 2015, 5: CD009311. |
| Cheuk K.L.D., Chiang A.K.S., Chan G.C.F. and Ha S.Y., Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer, Cochrane database of Systematic Reviews. 2014, CD006945. |
| Chiang A.K.S., Chair of session. Cancer 2014 – The Tenth Asia Pacific Multidisciplinary Meeting for Cancer Research, The Chinese University of Hong Kong, Hong Kong, 2014. |
| Chiang A.K.S., Clinical experience of Clofarabine-Based chemotherapy regimens in salvage therapy for relapsed and refractory leukemia in children, HST-EHA Joint Symposium and Special Lecture, Taiwan and Japan Hematology Forum, Taiwan. 2015. |
| Chiang A.K.S., Clinical spectrum of EBV-positive lymphoproliferative diseases in Chinese children, Institute of Experimental Immunology, University of Zurich. 2015. |
| Chiang A.K.S., NING J. and Chan K.H., Emergence of highly functional antigen-specific T cells towards Epstein-Barr virus corresponds to viral control and enhanced cytotoxicity in children with infectous mononucleosis and primary asymptomatic infection, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Chiang A.K.S., Kwok H., Palser A.L. and Kwong D.L.W., Genomic diversity of Epstein-Barr virus genomes isolated from primary nasopharyngeal carcinoma biopsies, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Chiang A.K.S., Induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies by histone deacetylase inhibitors, International Forum for Herpesvirus, Associated Diseases and Antiviral Development, Sun Yat-Sen University, Guangzhou, China. 2014. |
| Chiang A.K.S., Long Service Awards (15 years), The University of Hong Kong . 2015. |
| Chiang A.K.S., Novel organic compounds for induction of lytic cycle of EBV in nasopharyngeal carcinoma, The Croucher Foundation Advanced Study Institute on Advances in Nasopharyngeal Carcinoma Studies, Hong Kong. 2014. |
| Chiang A.K.S., YEUNG P.L. and Hui K.F., Targeting EBV in EBV-associated malignancies, Keystone Symposia Conference – Viruses and Human Cancer, Montana, USA. 2015. |
| Chiang A.K.S., Targeting Epstein-Barr virus in EBV-positive lymphoproliferative disorders and epithelial cancers, Golden Jubilee Scientific Meeting, Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Chu W.Y., Cheuk K.L.D., Chung B.H.Y., Bowers N.L., Ha S.Y., Chiang A.K.S. and Chan G.C.F., A patient with mosaic neurofibromatosis type 2 presenting with early onset meningioma, British Medical Journal. 2014. |
| DEE C.M.A., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Incidence of deferasirox-induced renal tubular dysfunction in children and young adults with beta-thalassemia., British Journal of Haematology. 2014, 167: 434-436. |
| Hau P.M., Deng W., Jia L.J., YANG J., Tsurumi T., Chiang A.K.S., Huen M.S.Y. and Tsao G.S.W., Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells, Journal of Virology. 2015, 89: 652-668. |
| Hui K.F., CHOI C.K., YEUNG P.L., Cheung A.K., Middeldorp J.M., Lung M.L., Tsao G.S.W. and Chiang A.K.S., A potent class I histone deacetylase inhibitor romidepsin induced lytic cycle of Epstein-Barr virus (EBV) in EBV-positive epithelial malignancies, Golden Jubilee Scientific Meeting (Oral Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., YEUNG P.L. and Chiang A.K.S., Bortezomib synergizes with romidepsin to induce apoptosis and autophagy in gastric carcinoma cells in vitro and in vivo, Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., YEUNG P.L., Middeldorp J.M. and Chiang A.K.S., Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines, Br J Haematol.. John Wiley & Sons Ltd., 2014, 167(5): 639-50. |
| Hui K.F. and Chiang A.K.S., Combination of proteasome and class I Histone Deacetylase (HDAC) inhibitors induces apoptosis of nasopharyngeal carcinoma cells through an HDAC6-independent ER stress-induced mechanism, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., CHOI C.K., YEUNG P.L., Middeldorp J.M., Tsao G.S.W. and Chiang A.K.S., Inhibition of class I Histone Deacetylases (HDACs) by HDAC inhibitors leads to the induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-positive epithelial malignancies, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., CHOI C.K., YEUNG P.L., MIDDELDORP J.M., Tsao G.S.W. and Chiang A.K.S., Inhibition of class I histone deacetylases (HDACs) by HDAC inhibitiors leads to the induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Kwok H., Chan K.W., Chan K.H. and Chiang A.K.S., Distribution, persistence and interchange of Epstein-Barr virus strains among PBMC, plasma and saliva of primary infection subjects , Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Kwok H., Wu C.W., Palser A.L., Kellam P., Shum P.C., Kwong D.L.W. and Chiang A.K.S., Genomic diversity of Epstein-Barr Virus genomes isolated from primary nasopharyngeal carcinoma biopsies, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Kwok H., Wu C.W., Palser A.L., Kellam P., Sham P.C., Kwong D.L.W. and Chiang A.K.S., Genomic diversity of Epstein-Barr virus genomes isolated from primary nasopharyngeal carcinoma biopsy samples, In: Kwok H, Wu CW, Palser AL, Kellam P, Sham PC, Kwong DL, Chiang AKS, Journal of Virology. 2014, 88(18):10662: DOI:10.1128/JVI.01665-14. |
| Liu A.P.Y., Lee V. and Chiang A.K.S., Refractory Acute Lymphoblastic Leukemia in Chinese Children: Bridging to Stem Cell Transplantation with Clofarabine-Based Regimen, 43rd Annual Scientific Meeting, The Hong Kong Society of Haematology, Free paper session. 2015. |
| So J.C.C., Chiang A.K.S., Kan S.Y.A., Lee V.C.Y. and Ng E.H.Y., Beta thalassaemia intermedia due to silent alpha globin gene quadruplication in an infant, Pathology. 2014, 46: 570-572. |
| WONG A.M.G., NING J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric liver transplant recipients who developed post-transpleant lymphoproliferative disorder, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Wong A.M.G., Ning J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr Virus in paediatric liver translplant recipients who developed post-transplant lymphoproliferative disorder, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong, . 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder. , Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder, 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates P16INK4A and P21WAF1 and induces apoptosis of EBV-Transformed lymphoblastoid cell lines, 21st Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates P16INK4A and P21WAF1 and induces apoptosis of EBV-Transformed lymphoblastoid cell lines, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2014. 2015. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates p16INK4A and p21WAF1 and induces apoptosis of EBV-transformed lymphoblastoid cell lines, 16th International Symposium on EBV and Associated Diseases. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of histone deacetylase and proteasome inhibitors induces synergistic killing of Epstein-Barr virus-transformed lymphoblastoid cell lines through counteracting the anti-apoptotic mechanism of EBNA-3 proteins , 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of histone deacetylase and proteasome inhibitors induces synergistic killing of Epstein-Barr virus-transformed lymphoblastoid cell lines through counteracting the anti-apoptotic mechanism of EBNA-3 proteins, Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : Chiu IWS |
| List of Research Outputs |
| Wong W.H.S. and Chiu I.W.S., The Impact of Habit of Eating Breakfast and Physical Activity on Children Suicidal Behaviour, International Journal of Behavioral Research & Psychology. SciDoc, 2015, 3(4): 99-104. |
| Researcher : Chiu SSS |
| Project Title: | Streptococcus pneumoniae carriage in young children in Hong Kong |
| Investigator(s): | Chiu SSS, Ho PL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health Services Research Fund - Full Grants |
| Start Date: | 10/1999 |
| Project Title: | Impact of universal vaccination with the 7-valent conjugate pneumocccal vaccine (PCV7) in Hong Kong on the incidence of pneumonia hospitalization and carriage in children |
| Investigator(s): | Chiu SSS, Ho PL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Centre for Health Protection |
| Start Date: | 07/2010 |
| Project Title: | A prospective longitudinal study to correlate maternal antibodies against influenza A and B with influenza infection and hospitalization in the first 6 months of life |
| Investigator(s): | Chiu SSS, Cowling BJ, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2014 |
| List of Research Outputs |
| Chiu S.S.S., Ho P.L., Peiris J.S.M., Chan K.H. and Chan L.Y., Population-based hospitalization incidence of respiratory viruses in community-acquired pneumonia in children younger than 5 years of age, Influenza and Other Respiratory Viruses. 2014, 8(6): 626-7. |
| Chiu S.S.S., Ho P.L., Khong P.L., Ooi C.G.C., So L.Y., Wong W.H.S. and Chan L.Y., Population-based incidence of community-acquired pneumonia hospitalization in Hong Kong children younger than 5 years before universal conjugate pneumococcal immunization. , Journal of Microbiology, Immunology and Infection. 2014. |
| Cowling B.J., Chan K.H., Feng S., Chan L.Y., Lo J.Y.C., Peiris J.S.M. and Chiu S.S.S., The effectiveness of influenza vaccination in preventing hospitalizations in children in Hong Kong, 2009–2013, Vaccine. Elsevier, 2014, 32: 5278-5284. |
| Ho P.L., Chiu S.S.S., LAW Y.T., Chan L.Y., Lai E.L.Y. and Chow K.H., Increase in the nasopharyngeal carriage of non-vaccine serogroup 15 Streptococcus pneumoniae after introduction of children pneumococcal conjugate vaccination in Hong Kong, Diagnostic Microbiology and Infectious Disease. 2015, 81: 145-148. |
| Researcher : Chong CY |
| List of Research Outputs |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Chow CB |
| Project Title: | A geographical study of child injury in Hong Kong: Spatial variation among 18 districts |
| Investigator(s): | Chow CB, Ip P, Wong WHS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health Care and Promotion Fund - Research Grant Projects |
| Start Date: | 09/2013 |
| Project Title: | Measuring the burden of fatal and nonfatal injury in Hong Kong |
| Investigator(s): | Chow CB, Ip P, McGhee S, Tsui MSH, Kam CW, Chan EW, Wong WHS, Chiu IWS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 07/2014 |
| List of Research Outputs |
| Abraham A., Wong W.H.S., Lee A., Louie L.H.T., Nelson E.A.S., Ho K.W., So H.K., Wong R.S.M., Yu C., Cheung T.K., Yue S.K., Lam S.F., Chow W.C., Chow C.B. and Ip P., Promoting Physical Activity among Adolescents in Hong Kong, Hong Kong College of Paediatricans, Annual Scientific Meeting, 6 December 2014. |
| Ho F...K...W., Louie L...H...T., Chow C.B., Wong W.H.S. and Ip P., Physical activity improves mental health through resilience in Hong Kong Chinese adolescents BMC Pediatrics, 2015. |
| Ip P., Wong R.S.M., Li S.L., Chan E.K.L., Ho F...K... and Chow C.B., Mental Health Consequences of Childhood Physical Abuse in Chinese Populations: A Meta-analysis. Trauma, Violence, & Abuse, 2015. |
| Lai P.C., Chow C.B., Wong H.T., Kwong K.H., Kwan Y.W., Liu S.H., Tong W.K., Cheung W.K. and Wong W.L., An early warning system for detecting H1N1 disease outbreak – a spatio-temporal approach, International Journal of Geographical Information Science. 2015, 29(7): 1251-1268. |
| Lam L...P..., Leung W...C..., Ip P., Chow C.B., Chan M...F..., Ng J...W...Y., Sing C., Lam Y...H..., Mak W...L...T., Chow K...M... and Chin R...K...H., Validation of the Drug Abuse Screening Test (Dast-10): A Study on Illicit Drug Use among Chinese Pregnant Women', Sci. Rep, 2015. |
| Man K.C.K., Ip P., Hsia Y., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A.W.Y. and Wong I.C.K., ADHD Drug Prescribing Trend Is Increasing Among Children and Adolescents in Hong Kong, Journal of Attention Disorders published online 3 July 2014. 2014. |
| Mok W.K.Y., Wong W.H.S., Mok T.K.G., Chu W.Y., HO K.W., Chow C.B., Ip P. and Chung B.H.Y., Validation and application of health utilities index in Chinese subjects with Down Syndrome, Health and Quality of Life Outcomes. 2014, 12(1): 144. |
| Wong W.H.S., Li S.L., Fu K.W., Tinsley H.M., Chow C.B. and Ip P., The importance of online resources for parents of children with special needs in Hong Kong: South China's experience. Journal of Health and Medical Informatics, 2015. |
| Researcher : Chow PC |
| List of Research Outputs |
| MAK C.C.Y., Chow P.C., Chau A.K.T., Chan Y.K., Bassett A.S. and Chung B.H.Y., Clinical implications of large rare copy number variations in 110 Chinese patients with conotruncal heart disease (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Researcher : Chu WY |
| List of Research Outputs |
| Chu W.Y., Cheuk K.L.D., Chung B.H.Y., Bowers N.L., Ha S.Y., Chiang A.K.S. and Chan G.C.F., A patient with mosaic neurofibromatosis type 2 presenting with early onset meningioma, British Medical Journal. 2014. |
| Chu W.Y., Chan S.S.K., Parents of Little People H.K. and Chung B.H.Y., Challenges faced by little people of Hong Kong - Narrative medicine in clinical genetics practice (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Fung G.P.C., Chu W.Y., Chan H.B., Oufadem M., Amiel J., Gordon C.T., Chung B.H.Y. and Tan T.Y., Mandibulofacial dysostosis with microcephaly caused by a novel "EFTUD2" mutation in a Chinese infant (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| LEUNG K.C., Ma C.H., Gao W., Chu W.Y., Wong W.L., Jin D., Lo I.F.M., Luk H.M. and Chung B.H.Y., Contribution of gain-of-function mutations in R1T1 to the pathogenesis of Noonan syndrome - A report of 3 new Chinese patients in Hong Kong (1st runner-up prize of best oral presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Mok T.K.G., Chu W.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics. Medcom Limited, 2015, 20(2): 118-119. |
| Mok T.K.G., Luk H.M., Chu W.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics, new series. 2014, 19: 265. |
| Mok W.K.Y., Wong W.H.S., Mok T.K.G., Chu W.Y., HO K.W., Chow C.B., Ip P. and Chung B.H.Y., Validation and application of health utilities index in Chinese subjects with Down Syndrome, Health and Quality of Life Outcomes. 2014, 12(1): 144. |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality – A new condition identified by exome sequencing? , Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 206. |
| Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014. |
| Researcher : Chua GT |
| List of Research Outputs |
| Chua G.T., Chow K.C., So J.C.C. and Cheuk K.L.D., Aleukaemic leukaemia presenting with pathological fracture, Case Reports. 2014, 2014: bcr2014204690-bcr2014204690. |
| Researcher : Chung BHY |
| Project Title: | Provision of molecular diagnosis for patients with birth defects/genetic conditions in Hong Kong |
| Investigator(s): | Chung BHY, Lau YL, Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 02/2012 |
| Project Title: | Comprehensive genetic evaluation of children with autism spectrum disorders in Hong Kong |
| Investigator(s): | Chung BHY, Wong VCN, Lee SL, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 08/2012 |
| Project Title: | Copy-number variations in Chinese patients with conotruncal defects - a pilot study of 100 patients |
| Investigator(s): | Chung BHY, Liu APY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Heart Foundation - General Award |
| Start Date: | 03/2013 |
| Project Title: | Identification of DNA methylation changes in Chinese patients with early-onset Systemic Lupus Erthematosus by bisulfite-converted DNA pyrosequencing |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2013 |
| Completion Date: | 05/2015 |
| Project Title: | Genomic Medicine for All - State of Art Testing for Hong Kong Children with Genetic Conditions |
| Investigator(s): | Chung BHY, Lau YL, Yang W, Sham PC, Chan YK |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 01/2014 |
| Project Title: | Cell lineage-specific differential DNA methylation in Chinese patients with early-onset systemic lupus erythematosus: implications for disease susceptibility |
| Investigator(s): | Chung BHY, Lau YL, Yang W, Lee PPW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Project Title: | Does the pattern of X Inactivation affect the phenotypic severity of patients with Triple X (XXX) syndrome? |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Project Title: | 2014 David W. Smirth Workshop on Malformations and Morphogenesis; Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2014 |
| Completion Date: | 07/2014 |
| Project Title: | Identifying the causality of a novel variant – A candidate mutation leading to cerebellar hypoplasia |
| Investigator(s): | Chung BHY, Ying D |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2015 |
| List of Research Outputs |
| AU YEUNG K.Y.G., Zayts O.A., Sarangi S. and Chung B.H.Y., With others and for others: Accounting for decisions about genetic testing in the clinic, Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 197-198. |
| Au Yeung K.Y.G., Zayts O.A. and Chung B.H.Y., Accounting for decisions about genetic testing: The case of Chinese families in Hong Kong, 13th Annual COMET 2015, HKU, 25-27 June 2015. |
| Chad L., Chung B.H.Y., Marshall C.R., Merico D., Babul-Hirji R., Stavropoulos J. and Chitayat D., Global developmental delay and characteristic facial features associated with PACS1 mutation- Report of two cases, CCMG 38th Annual Scientific Conference, Vancouver, Canada, 3-9 November 2014. |
| Chaudhry A., Noor A., Degagne B., Baker K., Bok L.A., Brady A.F., Chitayat D., Chung B.H.Y., Cytrynbaum C., Dyment D., Filges I., Helm B., Hutchison H.T., Jeng L.J.B., Laumonnier F., Marshall C.R., Menzel M., Parkash S., Parker M.J., The D.D.D. .S.T.U.D.Y., Raymond F.L., Rideout A.L., Roberts W., Rupps R., Schanze I., Schrander-Stumpel C.T.R.M., Speevak M.D., Stavropoulos D.J., Stevens S.J.C., Thomas E.R.A., Toutain A., Vergano S., Weksberg R., Scherer S.W., Vincent J.B. and Carter M.T., Phenotypic spectrum associated with PTCHD1 deletion and truncating mutations includes intellectual disability and autism spectrum disorder, Clinical Genetics. 2014. |
| Chonufani S., Cytrynbaum C., Chung B.H.Y., Turinsky A.L., Grafodatskaya D., Chen Y.A., Luk H.M., Lo I.F.M., Lam S.T.S., Stavropoulos D.J., Gibson B., Reardon M., Brudno M., Mendoza-Londono R., Chitayat D. and Weksberg R., NSD1+/- DNA methylation (DNAm) signature: A novel functional diagnostic tool for Sotos syndrome, 64th American Society of Human Genetics Annual Meeting (ASHG) 2014, San Digeo, USA, 18-22 October 2014. |
| Chu W.Y., Cheuk K.L.D., Chung B.H.Y., Bowers N.L., Ha S.Y., Chiang A.K.S. and Chan G.C.F., A patient with mosaic neurofibromatosis type 2 presenting with early onset meningioma, British Medical Journal. 2014. |
| Chu W.Y., Chan S.S.K., Parents of Little People H.K. and Chung B.H.Y., Challenges faced by little people of Hong Kong - Narrative medicine in clinical genetics practice (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Chung B.H.Y., Adviser, Marfan Syndrome Association. 2014. |
| Chung B.H.Y., Board Director, Association of Chinese Geneticists in Anerica (ACGA). 2014. |
| Chung B.H.Y., CFTR: p.I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with Cystic Fibrosis, 64th American Society of Human Genetics Annual Meeting (ASHG) 2014, San Digeo, USA, 18-22 October 2014. |
| Chung B.H.Y., Chairman, 11th Asian Society for Pediatric Research, (ASPR 2015) "Smile for Children in Asia", Osaka, Japan 15-18 April 2015. 2015. |
| Chung B.H.Y., Clinical Genetics: Pearls for Paediatricians, Canossa Hospital (Caritas). 2015. |
| Chung B.H.Y., Clinical implications of large rare copy number variation in 110 Chinese patients with conotruncal heart disease [poster presentation], 11th Asian Society for Pediatric Research, (ASPR 2015) "Smile for Children in Asia, 15-18 April 2015. |
| Chung B.H.Y., Common Genetic Diseases in Children & Genetic Counseling, The Core Module for Post-registration Certificate Course in Paediatric Nursing, HK, 12 November 2014. 2014. |
| Chung B.H.Y., Common Genetic Diseases in Children & Genetic Counseling, The Core Module of the Post-Registration Course in Paediatric Specialty Nursing. 2015. |
| Chung B.H.Y., Congenital heart disease: genetic evaluation and counselling, Paediatric Cardiology Symposium, HK College of Cardiology, 15 November 2014. 2014. |
| Chung B.H.Y., Epigenetics and Health Risks with Tobacco Exposure, Hong Kong Paediatric Foundation - 20th Anniversary Conference, Summit on Child Health & the Environment 2014, The HK Paediatric Society, 11-13 October 2014. 2014. |
| Chung B.H.Y., Epigenetics and health risks with tobacco exposure, Hong Kong Paediatric Foundation - 20th Anniversary Conference, Summit on Child Health and the Environment 2014, Session of "Tobacco and Impact of second-hand smoke on Children's Health". 2014. |
| Chung B.H.Y., Evaluating children with ASD in the genetics clinic, Genetics and Epidemiology in Autism 2014, HK, 20 November 2014. 2014. |
| Chung B.H.Y., Expert Panel Member, Council of the Hong Kong Paediatric Society, 4 March 2015-3 March 2017. 2015. |
| Chung B.H.Y., Founding Member, 22q Society. 2014. |
| Chung B.H.Y., From clinics to genomic research: personalized medicine or "just a case report", 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Chung B.H.Y., Genetic Counselling for you and me, HKU Space. 2015. |
| Chung B.H.Y., Genetic counseling for pre-implantation genetic diagnosis, Hong Kong Sanatorium & Hospital presents CME in Obstetrics & Gynaecology, 20 March 2015. 2015. |
| Chung B.H.Y., Genetic counseling for you and me, HKU Space, 6 June 2015. 2015. |
| Chung B.H.Y., Genetics in Paediatric Office Setting, Professional Continual Medical Education Series 2015 of The Hong Kong Paediatric Society (HKPS), 28 April 2015. 2015. |
| Chung B.H.Y., Genetics of Connective Tissues, Hong Kong Marfan Syndrome Association, St. Paul's Hospital, 26 March 2015. 2015. |
| Chung B.H.Y., Genius in your genes?, China Daily Hong Kong Newspaper, 31 March 2015. 2015. |
| Chung B.H.Y., Identifying genetic mutations in patients with rasopathies using a next generation sequencing diagnostic pipeline in Hong Kong [poster presentation], 11th Asian Society for Pediatric Research, (ASPR 2015) "Smile for Children in Asia, 15-18 April 2015. |
| Chung B.H.Y., Interesting patients with neurogenetic conditions from HK, Central Committee (Genetic Services) Commissioned Training "Clinical Genetics - from bed side to bench side and back to bed side", 13-14 February 2015. 2015. |
| Chung B.H.Y., Judges for the St John's College 2015 Academic Spring Colloquium, Academic and Research Committee of St John's College. 2015. |
| Chung B.H.Y., Member, Special Study Module (SSM) & Sub-Committee, HKU. 2015. |
| Chung B.H.Y., Membership of the Grant Review Board (GRB), 7 Jan 2015-30 Sept 2016, Health and Medical Research Fund (HMRF). 2015. |
| Chung B.H.Y., Organizing Committee, 13th Annual COMET 2015, HKU, 25-27 June 2015. 2015. |
| Chung B.H.Y., Paediatric diseases, Molecular Diagnostic Laboratory (BBMS3004), HKU, 27 April 2015. 2015. |
| Chung B.H.Y., Panel 1 Chairman, 13th Annual COMET 2015, HKU, 25-27 June 2015. 2015. |
| Chung B.H.Y., Reviewer, COMET 2015. 2015. |
| Chung B.H.Y., Reviewer, European Journal of Pediatrics. 2015. |
| Chung B.H.Y., Reviewer, Human Molecular Genetics. 2015. |
| Chung B.H.Y., Reviewer, International Journal of Rheumatic Diseases. 2014. |
| Chung B.H.Y., Reviewer, Journal of Clinical Sciences. 2015. |
| Chung B.H.Y., Reviewer, Journal of Human Genetics. 2015. |
| Chung B.H.Y., Reviewer, Orphanet Journal of Rare Diseases. 2014. |
| Chung B.H.Y., Reviewer, PLOS One. 2014. |
| Chung B.H.Y., Reviewer, Pediatric Reserach. 2015. |
| Chung B.H.Y., Reviewer, Research in Autism Spectrum Disorders. 2014. |
| Chung B.H.Y., Somatic Mosaicism of PIK3CA Mutation in PI3K-AKT Pathway Related Overgrowth Disorders, CRGD & SRT Joint Symposium, HKU, 12 December 2014. 2014. |
| Chung B.H.Y., 遺傳學咨詢輔導, Symposium in "Frontiers in Assisted Reproduction and Reproductive Genetics", Shenzhen Hospital, 1 November 2014. |
| Chung B.H.Y., Whole-exome sequencing identified CC2D1A as the candidate gene for right isomerism [oral presentation], 11th Asian Society for Pediatric Research, (ASPR 2015) "Smile for Children in Asia, 15-18 April 2015. |
| Chung B.H.Y., TVB 星期日檔案 - 罕見疾病: 侏儒症, 2014. |
| Chung B.H.Y., Oriental Daily News – 保護罕見病患者 港法例落後, 2014. |
| Chung B.H.Y. and Chung B.H.Y., Oriental Daily News – 沒遺傳學訓練 須海外進修, 2014. |
| Chung B.H.Y., Oriental Daily News – 港醫生乏訓練 罕見病乏支援, 2014. |
| Chung B.H.Y., 不能不認識的兒童病系列 5 - BB 營養由媽咪懷孕開始, 2014, 1-153. |
| Chung B.H.Y., X 染色體脆弱症 影響智能發展, Oriental Daily Health Column, 2014. |
| Chung B.H.Y., 眼疾與遺傳基因的關係, 香港視網膜病變協會研討會 2014, 6 December 2014, 2014. |
| Chung B.H.Y., 一個都不能少, 香港電台 - 鏗鏘集, 2014. |
| Chung B.H.Y., 罕見疾病: 侏儒症, 星期日檔案, 無線電視, 12 October 2014, 2014. |
| Fung G.P.C., Chu W.Y., Chan H.B., Oufadem M., Amiel J., Gordon C.T., Chung B.H.Y. and Tan T.Y., Mandibulofacial dysostosis with microcephaly caused by a novel "EFTUD2" mutation in a Chinese infant (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Fung W.L.A., Butcher N.J., Costain G., Andrade D.M., Boot E., Chow E.W.C., Chung B.H.Y., Cytrynbaum C., Faghfoury H., Fishman L., Garcia-Minaur S., Geroge S., Lang A.E., Repetto G., Shugar A., Silversides C., Swillen A., van Amelsvoort T., McDonald-McGinn D.M. and Bassett A.S., Practical guidelines for managing adults with 22q11.2 deletion syndrome, Genetics in Medicine. 2015. |
| Inbar-Feigenberg M., Chung B.H.Y., Marshall C.R., Merico D., Stavropoulos D.J. and Chitayat D., Agenesis of the Corpus Callosum and Autism associated with ZEB1 gene deletion - A case report, CCMG 38th Annual Scientific Conference, Vancouver, Canada, 3-9 November 2014. |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| LEUNG K.C., Ma C.H., Gao W., Chu W.Y., Wong W.L., Jin D., Lo I.F.M., Luk H.M. and Chung B.H.Y., Contribution of gain-of-function mutations in R1T1 to the pathogenesis of Noonan syndrome - A report of 3 new Chinese patients in Hong Kong (1st runner-up prize of best oral presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Liu A.P.Y., Chan G.C.F., Chung B.H.Y. and So J.C.C., Infant onset pancytopenia: A Case Report of Fanconi Anaemia managed with Matched-Sibling Cord Blood Transplantation (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| MAK C.C.Y., Chow P.C., Chau A.K.T., Chan Y.K., Bassett A.S. and Chung B.H.Y., Clinical implications of large rare copy number variations in 110 Chinese patients with conotruncal heart disease (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| Marchegiani S., Davis T., Tessadori F., van Haaften G., Brancati F., Hoischen H., Huang H., Valkanas E., Pusey B., Schanze D., Venselaaar H., Vulto-van Silfhourt A.T., Wolfe L.A., Tifft C.J., Zerfas P.M., Zambruno G., Kariminejad A., Kermani F.S., Lee J., Tsokos M.G., Lee C.C.R., Ferraz V., da Silva E.M., Stevens C.A., Roche N., Bartsch O., Farndon P., Bermejo-Sanchez E., Brooks B.P., Maduro V., Dallapiccola B., Ramos F.J., Chung B.H.Y., Caignec C.L., Martins F., Jacyk W.K., Mazzanti L., Brunner H.G., Bakkers J., Lin S., Malicdan M.C.V., Boerkoel C.F., Gahl W.A., de Vries B.B.A., van Haelst M.M., Zenker M. and Markello T., Recurrent mutations in the basic domain of TWIST2 cause Ablepharon Macrostomia syndrome and Barber-Say syndrome, American Journal of Human Genetics. 2015, 97(1): 99-110. |
| Mok T.K.G., Chu W.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics. Medcom Limited, 2015, 20(2): 118-119. |
| Mok T.K.G., Chiang J.P.W., Yeung J.C.C. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(3): 207. |
| Mok T.K.G., Luk H.M., Chu W.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics, new series. 2014, 19: 265. |
| Mok T.K.G., Ng G.H.T., Kwok M.K.A. and Chung B.H.Y., What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2015, 20: 41-42. |
| Mok W.K.Y., Wong W.H.S., Mok T.K.G., Chu W.Y., HO K.W., Chow C.B., Ip P. and Chung B.H.Y., Validation and application of health utilities index in Chinese subjects with Down Syndrome, Health and Quality of Life Outcomes. 2014, 12(1): 144. |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| YEUNG K.S., LEUNG K.C., Wong W.L., Li R.C.H., Choi K.Y., Kuong E.Y.L., Chow W., To M., Chan G.C.F. and Chung B.H.Y., Somatic Mosicism of PIK3CA mutation In PIK3CA-related overgrowth disorders (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| YEUNG K.S., Chee W.Y.Y., Luk H.M., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Shuen A.Y., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Spread of X Inactivation on Chromosome 15 is Associated with a More Severe Phenotype in a Girl with an Unbalanced t(X;15) Translocation, American Journal of Medical Genetics (Part A). 2014, 164(10): 2521-2528. |
| Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality – A new condition identified by exome sequencing? , Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 206. |
| Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zayts O.A. and Chung B.H.Y., "It's like throwing a dice". The management of extreme uncertainty and decision-making in the age of genome medicine: The case of pre-conception counselling, 13th Annual COMET 2015, HKU, 25-27 June 2015. |
| Zayts O.A. and Chung B.H.Y., Interdisciplinary Collaboration between Medical Professionals and Sociolinguists, Knowledge Exchange (KE) Lunch Meeting, HKU. 2014. |
| Zayts O.A. and Chung B.H.Y., Interdisciplinary collaboration between medical professionals and sociolinguists., Invited lecture at the Knowledge Exchange (KE) Lunch Meetings organized by the KE Office, HKU, 22 Sep 2014. . 2014. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : DEE CMA |
| List of Research Outputs |
| DEE C.M.A., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Incidence of deferasirox-induced renal tubular dysfunction in children and young adults with beta-thalassemia., British Journal of Haematology. 2014, 167: 434-436. |
| Researcher : GAO Y |
| List of Research Outputs |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |
| Researcher : HO KW |
| List of Research Outputs |
| Abraham A., Wong W.H.S., Lee A., Louie L.H.T., Nelson E.A.S., Ho K.W., So H.K., Wong R.S.M., Yu C., Cheung T.K., Yue S.K., Lam S.F., Chow W.C., Chow C.B. and Ip P., Promoting Physical Activity among Adolescents in Hong Kong, Hong Kong College of Paediatricans, Annual Scientific Meeting, 6 December 2014. |
| Mok W.K.Y., Wong W.H.S., Mok T.K.G., Chu W.Y., HO K.W., Chow C.B., Ip P. and Chung B.H.Y., Validation and application of health utilities index in Chinese subjects with Down Syndrome, Health and Quality of Life Outcomes. 2014, 12(1): 144. |
| Researcher : HUANG Y |
| List of Research Outputs |
| HUANG Y., Yang J., Ying D., Zhang Y., Shotelersuk V., Hirankarn N., Sham P.C., Lau Y.L. and Yang W., HLAreporter: a tool for HLA typing from next generation sequencing data, Genome Medicine. 2015, 7(1): 25. |
| Researcher : Ha SY |
| List of Research Outputs |
| Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Interventions for prophylaxis of hepatic veno-occlusive disease in people undergoing heamatopoietic stem cell transplantation, Cochrane Database Systematic Review. 2015, 5: CD009311. |
| Cheuk K.L.D., Chiang A.K.S., Chan G.C.F. and Ha S.Y., Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer, Cochrane database of Systematic Reviews. 2014, CD006945. |
| Chu W.Y., Cheuk K.L.D., Chung B.H.Y., Bowers N.L., Ha S.Y., Chiang A.K.S. and Chan G.C.F., A patient with mosaic neurofibromatosis type 2 presenting with early onset meningioma, British Medical Journal. 2014. |
| DEE C.M.A., Cheuk K.L.D., Chiang A.K.S., Ha S.Y. and Chan G.C.F., Incidence of deferasirox-induced renal tubular dysfunction in children and young adults with beta-thalassemia., British Journal of Haematology. 2014, 167: 434-436. |
| Researcher : Ho KW |
| List of Research Outputs |
| Abraham A., Wong W.H.S., Lee A., Louie L.H.T., Nelson E.A.S., Ho K.W., So H.K., Wong R.S.M., Yu C., Cheung T.K., Yue S.K., Lam S.F., Chow W.C., Chow C.B. and Ip P., Promoting Physical Activity among Adolescents in Hong Kong, Hong Kong College of Paediatricans, Annual Scientific Meeting, 6 December 2014. |
| Mok W.K.Y., Wong W.H.S., Mok T.K.G., Chu W.Y., HO K.W., Chow C.B., Ip P. and Chung B.H.Y., Validation and application of health utilities index in Chinese subjects with Down Syndrome, Health and Quality of Life Outcomes. 2014, 12(1): 144. |
| Researcher : Ho MHK |
| List of Research Outputs |
| Ho M.H.K., 小童患食物過敏 部分可致命, Oriental Daily News, 14 February 2015. 2015. |
| Lee T.H. and Ho M.H.K., Asthma patients often underestimate severity of symptoms, South China Morning Post. 2014. |
| Wai C.Y.Y., Leung N.Y.H., Ho M.H.K., Gershwin L.J., Shu S.A., Leung P.S.C. and Chu K.H., Immunization with Hypoallergens of Shrimp Allergen Tropomyosin Inhibits Shrimp Tropomyosin Specific IgE Reactivity, PLOS One. 2014, 9(11): e111649. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Hui KF |
| Project Title: | Investigation of histone modification on induction of Epstein-Barr virus lytic cycle in nasopharyngeal carcinoma |
| Investigator(s): | Hui KF, Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2013 |
| Completion Date: | 07/2014 |
| Project Title: | 16th international symposium on EBV and associated diseases; Inhibition of class I histone deacetylases (HDACs) by HDAC inhibitors leads to the induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies |
| Investigator(s): | Hui KF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2014 |
| Completion Date: | 07/2014 |
| Project Title: | Sensitization of nasopharyngeal carcinoma to radiotherapy and chemotherapy by induction of DNA damage response pathway |
| Investigator(s): | Hui KF, Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2015 |
| List of Research Outputs |
| CHOI C.K., Ho D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-positive epithelial malignancies, 21st Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| CHOI C.K., Ho D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies , 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong, . 2014. |
| CHOI C.K., HO D.N., Hui K.F., Kao R.Y.T. and Chiang A.K.S., Identification of novel small organic compounds for induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies, 16th International Symposium on EBV and Associated Diseases. 2014. |
| CHOI C.K., Hui K.F., Ho D.N., Kao R.Y.T. and Chiang A.K.S., Novel organic compounds for induction of lytic cycle of EBV in nasopharyngeal carcinoma, The Croucher Foundation Advanced Study Institute on Advances in Nasopharyngeal Carcinoma Studies, Hong Kong. 2014. |
| Chiang A.K.S., YEUNG P.L. and Hui K.F., Targeting EBV in EBV-associated malignancies, Keystone Symposia Conference – Viruses and Human Cancer, Montana, USA. 2015. |
| Hui K.F., CHOI C.K., YEUNG P.L., Cheung A.K., Middeldorp J.M., Lung M.L., Tsao G.S.W. and Chiang A.K.S., A potent class I histone deacetylase inhibitor romidepsin induced lytic cycle of Epstein-Barr virus (EBV) in EBV-positive epithelial malignancies, Golden Jubilee Scientific Meeting (Oral Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., Best Oral Presentation Award, UPAM Golden Jubilee Scientific Meeting, Department of Paediatrics, HKU. 2014. |
| Hui K.F., YEUNG P.L. and Chiang A.K.S., Bortezomib synergizes with romidepsin to induce apoptosis and autophagy in gastric carcinoma cells in vitro and in vivo, Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., YEUNG P.L., Middeldorp J.M. and Chiang A.K.S., Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines, Br J Haematol.. John Wiley & Sons Ltd., 2014, 167(5): 639-50. |
| Hui K.F. and Chiang A.K.S., Combination of proteasome and class I Histone Deacetylase (HDAC) inhibitors induces apoptosis of nasopharyngeal carcinoma cells through an HDAC6-independent ER stress-induced mechanism, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., CHOI C.K., YEUNG P.L., Middeldorp J.M., Tsao G.S.W. and Chiang A.K.S., Inhibition of class I Histone Deacetylases (HDACs) by HDAC inhibitors leads to the induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-positive epithelial malignancies, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., CHOI C.K., YEUNG P.L., MIDDELDORP J.M., Tsao G.S.W. and Chiang A.K.S., Inhibition of class I histone deacetylases (HDACs) by HDAC inhibitiors leads to the induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Hui K.F., Targeting Epstein-Barr virus lytic cycle in NPC cells by a potent class I histone deacetylase inhibitor romidepsin, Advanced Study Institute (ASI) on "Advances in NPC Studies", Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates P16INK4A and P21WAF1 and induces apoptosis of EBV-Transformed lymphoblastoid cell lines, 21st Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates P16INK4A and P21WAF1 and induces apoptosis of EBV-Transformed lymphoblastoid cell lines, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2014. 2015. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates p16INK4A and p21WAF1 and induces apoptosis of EBV-transformed lymphoblastoid cell lines, 16th International Symposium on EBV and Associated Diseases. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of histone deacetylase and proteasome inhibitors induces synergistic killing of Epstein-Barr virus-transformed lymphoblastoid cell lines through counteracting the anti-apoptotic mechanism of EBNA-3 proteins , 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of histone deacetylase and proteasome inhibitors induces synergistic killing of Epstein-Barr virus-transformed lymphoblastoid cell lines through counteracting the anti-apoptotic mechanism of EBNA-3 proteins, Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : Ip P |
| Project Title: | The Gap Between the Rich and the Poor: From School Readiness to School Success |
| Investigator(s): | Ip P, Bacon-Shone J, Rao N, Vere JP |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Project Title: | Can physical activity enhance sleep quality among adolescents? A randomised controlled trial |
| Investigator(s): | Ip P |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2014 |
| List of Research Outputs |
| Abraham A., Wong W.H.S., Lee A., Louie L.H.T., Nelson E.A.S., Ho K.W., So H.K., Wong R.S.M., Yu C., Cheung T.K., Yue S.K., Lam S.F., Chow W.C., Chow C.B. and Ip P., Promoting Physical Activity among Adolescents in Hong Kong, Hong Kong College of Paediatricans, Annual Scientific Meeting, 6 December 2014. |
| Chan E.K.L., Emery C.R. and Ip P., Children with disability are more at risk of violence victimization: evidence from a study of school-aged Chinese children. Journal of Interpersonal Violence, 2014. |
| Cheung K.K.W., Wong I.C.K., Ip P., Chan P.K.L., Lin H.Y.C., Wong L.Y.L. and Chan E.W., Experiences of adolescents and young adults with ADHD in Hong Kong: treatment services and clinical management, BMC Psychiatry. 2015, 15(1): 95. |
| Fu K.W., Chan C.H. and Ip P., Exploring the relationship between cyberbullying and unnatural child death: an ecological study of twenty-four European countries, BMC Pediatrics. BioMed Central, 2014, 14: 195. |
| Ho F...K...W., Louie L...H...T., Chow C.B., Wong W.H.S. and Ip P., Physical activity improves mental health through resilience in Hong Kong Chinese adolescents BMC Pediatrics, 2015. |
| Ip P., How to Improve Early Childhood Development?, PECERA, Hong Kong, 30 September 2014. 2014. |
| Ip P., How to Improve Early Childhood Development, PCERA (HK). 2014. |
| Ip P., Wong R.S.M., Li S.L., Chan E.K.L., Ho F...K... and Chow C.B., Mental Health Consequences of Childhood Physical Abuse in Chinese Populations: A Meta-analysis. Trauma, Violence, & Abuse, 2015. |
| Lam L...P..., Leung W...C..., Ip P., Chow C.B., Chan M...F..., Ng J...W...Y., Sing C., Lam Y...H..., Mak W...L...T., Chow K...M... and Chin R...K...H., Validation of the Drug Abuse Screening Test (Dast-10): A Study on Illicit Drug Use among Chinese Pregnant Women', Sci. Rep, 2015. |
| Man K.C.K., Ip P., Hsia Y., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A.W.Y. and Wong I.C.K., ADHD Drug Prescribing Trend Is Increasing Among Children and Adolescents in Hong Kong, Journal of Attention Disorders published online 3 July 2014. 2014. |
| Man K.C.K., Chan E.W., Douglas I., Ip P., Wong W.H.S., Coghill D. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder (ADHD) Pharmacological Treatment and Its Effect on Accident and Emergency Admission Due to Injury: A Self-Controlled Case-Series Study, 30th International Conference for Pharmacoepidemiology (ICPE). 2014. |
| Man K.C.K., Chan E.W., Coghill D., Douglas I., Ip P., Leung L.P., Tsui M.S.H., Wong W.H.S. and Wong I.C.K., Methylphenidate and the Risk of Trauma, PEDIATRICS. 2014, 135(1): 40-48. |
| Mok W.K.Y., Wong W.H.S., Mok T.K.G., Chu W.Y., HO K.W., Chow C.B., Ip P. and Chung B.H.Y., Validation and application of health utilities index in Chinese subjects with Down Syndrome, Health and Quality of Life Outcomes. 2014, 12(1): 144. |
| Rao N., Sun J., Chen E.E. and Ip P., Effectiveness of early childhood interventions in promoting cognitive development in developing countries: A systematic review, Biennial meeting of the Society for Research in Child Development Conference, Philadelphia, USA. 2015. |
| Rao N., Sun J., Ng M., Becher Y., Lee P.L.D., Ip P. and Bacon-Shone J., Preschool attendance and child development: Findings from the East Asia-Pacific Early Child Development Scales, Biennial meeting of the Society for Research in Child Development Conference, Philadelphia, USA.. 2015. |
| Rao N., Sun J., Ng M., Becher Y., Lee P.L.D., Ip P. and Bacon-Shone J., Validation, Finalization and Adoption of the East Asia-Pacific Early Child Development Scales (EAP-ECDS), UNICEF. 2014. |
| Sun J., Rao N., Ng M., Becher Y., Lee P.L.D., Ip P. and Bacon-Shone J., The role of adults’ cognitive and socio-emotional caregiving in early ethnic-related development gaps in Cambodia, biennial meeting of the Society for Research in Child Development Conference, Philadelphia, USA. 2015. |
| Wong W.H.S., Li S.L., Fu K.W., Tinsley H.M., Chow C.B. and Ip P., The importance of online resources for parents of children with special needs in Hong Kong: South China's experience. Journal of Health and Medical Informatics, 2015. |
| Zhang H., Wong C.W., Ip P., Fan S. and Yip P.S.F., Intimate Partner Violence among Hong Kong Young Adults: Prevalence, Risk Factors and Associated Health Problems. Journal of Interpersonal Violence, 2014. |
| Researcher : KUI L |
| List of Research Outputs |
| KUI L., Chan G.C.F., Lee P.P.W. and Lee P.P.W., Regulatory role of TSG-6 in TLR-9 signaling of type 1 interferon and cytokines in the innate immunity (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Researcher : Kwok H |
| List of Research Outputs |
| Kwok H., Chan K.W., Chan K.H. and Chiang A.K.S., Distribution, persistence and interchange of Epstein-Barr virus strains among PBMC, plasma and saliva of primary infection subjects , Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Kwok H., Wu C.W., Palser A.L., Kellam P., Shum P.C., Kwong D.L.W. and Chiang A.K.S., Genomic diversity of Epstein-Barr Virus genomes isolated from primary nasopharyngeal carcinoma biopsies, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Kwok H., Wu C.W., Palser A.L., Kellam P., Sham P.C., Kwong D.L.W. and Chiang A.K.S., Genomic diversity of Epstein-Barr virus genomes isolated from primary nasopharyngeal carcinoma biopsy samples, In: Kwok H, Wu CW, Palser AL, Kellam P, Sham PC, Kwong DL, Chiang AKS, Journal of Virology. 2014, 88(18):10662: DOI:10.1128/JVI.01665-14. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder. , Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder, 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : Kwok MKA |
| List of Research Outputs |
| Mok T.K.G., Ng G.H.T., Kwok M.K.A. and Chung B.H.Y., What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2015, 20: 41-42. |
| Researcher : LEUNG KC |
| List of Research Outputs |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| LEUNG K.C., Ma C.H., Gao W., Chu W.Y., Wong W.L., Jin D., Lo I.F.M., Luk H.M. and Chung B.H.Y., Contribution of gain-of-function mutations in R1T1 to the pathogenesis of Noonan syndrome - A report of 3 new Chinese patients in Hong Kong (1st runner-up prize of best oral presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| YEUNG K.S., LEUNG K.C., Wong W.L., Li R.C.H., Choi K.Y., Kuong E.Y.L., Chow W., To M., Chan G.C.F. and Chung B.H.Y., Somatic Mosicism of PIK3CA mutation In PIK3CA-related overgrowth disorders (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Researcher : LEUNG YY |
| List of Research Outputs |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates P16INK4A and P21WAF1 and induces apoptosis of EBV-Transformed lymphoblastoid cell lines, 21st Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates P16INK4A and P21WAF1 and induces apoptosis of EBV-Transformed lymphoblastoid cell lines, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2014. 2015. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates p16INK4A and p21WAF1 and induces apoptosis of EBV-transformed lymphoblastoid cell lines, 16th International Symposium on EBV and Associated Diseases. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of histone deacetylase and proteasome inhibitors induces synergistic killing of Epstein-Barr virus-transformed lymphoblastoid cell lines through counteracting the anti-apoptotic mechanism of EBNA-3 proteins , 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of histone deacetylase and proteasome inhibitors induces synergistic killing of Epstein-Barr virus-transformed lymphoblastoid cell lines through counteracting the anti-apoptotic mechanism of EBNA-3 proteins, Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : LU A |
| List of Research Outputs |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |
| Researcher : Lam KT |
| List of Research Outputs |
| Wu Y., Tu W., Lam K.T., Chow K.H., Ho P.L., Guan Y., Peiris J.S.M. and Lau Y.L., Lethal coinfection of influenza virus and Streptococcus pneumoniae lowers antibody response to influenza virus in lung and reduces numbers of germinal center B cells, T follicular helper cells, and plasma cells in mediastinal lymph Node., Journal of Virology. 2015, 89(4): 2013-23. |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |
| Researcher : Lam SF |
| List of Research Outputs |
| Abraham A., Wong W.H.S., Lee A., Louie L.H.T., Nelson E.A.S., Ho K.W., So H.K., Wong R.S.M., Yu C., Cheung T.K., Yue S.K., Lam S.F., Chow W.C., Chow C.B. and Ip P., Promoting Physical Activity among Adolescents in Hong Kong, Hong Kong College of Paediatricans, Annual Scientific Meeting, 6 December 2014. |
| Researcher : Lau ASY |
| Project Title: | Cytokines, Signaling & Diseases 2003 The Role of Protein Kinase PKR in the Induction of Cytokine Expression by Bacillus Calmette Guerin Through NF-kappaB |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2003 |
| Project Title: | Cytokine Dysregulation and Virus-Induced Cell Death in Avian Influenza Virus Infections |
| Investigator(s): | Lau ASY, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2005 |
| Project Title: | Factors affecting mycobacteria evasion of immunity: effects of HIV on cellular signaling and kinases |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 09/2009 |
| List of Research Outputs |
| Sun W., Yang L.H., Lau A.S.Y. and Li C.B., Inhibitory Effect of Panax Notoginseng (PNG) Extracts on the TNF-α-induced MMP-9 Activity in Cardiomyoblasts, 2014 Annual Scientific Meeting, Hong Kong College of Paediatricians. 2014. |
| Researcher : Lau YL |
| Project Title: | A community-based educational program on thalassaemias to enhance awareness with the aim to reduce burden of thalassaemia related health problems in Hong Kong |
| Investigator(s): | Lau YL, Ha SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health Promotion Projects |
| Start Date: | 09/1997 |
| Project Title: | Comparison of process upgrade varicella vaccine (Puvv) with VARILRIX-TM |
| Investigator(s): | Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/1999 |
| Project Title: | Association of cytokine and chemokine genes polymorphism with susceptibility to SARS and severity of SARS |
| Investigator(s): | Lau YL, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 09/2005 |
| Project Title: | p21 gene polymorphism with systemic lupus erythematosus and rheumatoid arthritis |
| Investigator(s): | Lau YL, Lau WCS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2005 |
| Project Title: | The effects of BTK mutation on TLR3-mediated type I IFN response against poliovirus infection in X-linked agammaglobulinemia |
| Investigator(s): | Lau YL, Tu W, Lee PPW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| List of Research Outputs |
| Anney R.J.L., Avbersek A., Balding D., Baum L., Becker F., Berkovic S.F., Bradfield J.P., Lau Y.L., Yang W. and Cherny S.S., Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies, The Lancet Neurology. 2014, 13: 893-903. |
| Chan Y.T.E., Ho H.K., Lai C.K.W., Lau W.C.S., Lau Y.L., Lee T.H., Leung T.F., Wong G.W.K. and Wu Y.Y., Allergy in Hong Kong: an unmet need in service provision and training, Hong Kong Medical Journal. 2015. |
| HUANG Y., Yang J., Ying D., Zhang Y., Shotelersuk V., Hirankarn N., Sham P.C., Lau Y.L. and Yang W., HLAreporter: a tool for HLA typing from next generation sequencing data, Genome Medicine. 2015, 7(1): 25. |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| PEI L.C.S., Wu Y., Lau Y.L. and Lee P.P.W., Possible role(s) of interferon regulation of inflammasome activity via autophagy (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| Tu W., Lau Y.L. and Peiris J.S.M., Use of humanised mice to study antiviral activity of human γδ-T cells against influenza A viruses, Hong Kong Medical Journal. 2014, 20(Suppl 6): S4-6. |
| Wu J.T.K., Lee C.K., Ho P.L., Hung I.F.N., Lin C.K., Lau Y.L., Leung G.M., Cowling B.J. and Peiris J.S.M., A Detailed Longitudinal Study of Infection Attack Rates Among Healthy Adults in Hong Kong During the Epidemic of the Human Swine Influenza A/H1N1 Virus in 2009, Health Research Symposium 2014, Hong Kong, 15 Nov 2014. (Poster presentation). 2014. |
| Wu J.T.K., Hung I.F.N., Lau Y.L., Peiris J.S.M. and Cowling B.J., A Longitudinal Study of Infection Attack Rates Among Hospital Outpatients in Hong Kong During Epidemic of the Human Swine Influenza A/H1N1 Virus in 2009 by Tracking Temporal Changes in Age-specific Seroprevalence Rates, Health Research Symposium 2014, Hong Kong, 15 Nov 2014. (Poster presentation). 2014. |
| Wu Y., Tu W., Lam K.T., Chow K.H., Ho P.L., Guan Y., Peiris J.S.M. and Lau Y.L., Lethal coinfection of influenza virus and Streptococcus pneumoniae lowers antibody response to influenza virus in lung and reduces numbers of germinal center B cells, T follicular helper cells, and plasma cells in mediastinal lymph Node., Journal of Virology. 2015, 89(4): 2013-23. |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| Ying D., Sham P.C., Smith D.K., ZHANG L., Lau Y.L. and Yang W., HaploShare: identification of extended haplotypes shared by cases and evaluation against controls, Genome Biology. 2015, 16: 92. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Lee PPW |
| Project Title: | Activation of autophagy limits IL-1beta production in monocytes expressing gain-of-function NLRP3 mutations |
| Investigator(s): | Lee PPW, Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 04/2014 |
| Project Title: | The role of NLRP3 inflammasome in the induction of protective Th1 and Th17 immune response towards Penicillium marneffei |
| Investigator(s): | Lee PPW, Lau YL, Woo PCY, Tu W, Chan JFW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Project Title: | Immunology of Fungal Infections; Inborn errors of immunity and Penicillium marneffei infections |
| Investigator(s): | Lee PPW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 01/2015 |
| Completion Date: | 01/2015 |
| List of Research Outputs |
| KUI L., Chan G.C.F., Lee P.P.W. and Lee P.P.W., Regulatory role of TSG-6 in TLR-9 signaling of type 1 interferon and cytokines in the innate immunity (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| PEI L.C.S., Wu Y., Lau Y.L. and Lee P.P.W., Possible role(s) of interferon regulation of inflammasome activity via autophagy (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Lee SL |
| List of Research Outputs |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| Researcher : Lee TL |
| List of Research Outputs |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Li CB |
| Project Title: | The role of c-Myc in anti-mycobaterial responses: from bacterial killing to T cell activation |
| Investigator(s): | Li CB, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | The effects of Coriolus Versicolor on TGF-beta induced tumor cell migration |
| Investigator(s): | Li CB |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 06/2014 |
| Project Title: | 5th International Human Microbiome Congress; A Possible Role Of IL-17 During Salmonella Typhimurium Infection |
| Investigator(s): | Li CB |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 03/2015 |
| Completion Date: | 04/2015 |
| List of Research Outputs |
| Li C.B., Outstanding Presentation Award, Hong Kong College of Paediatricians. 2014. |
| Ling W.L., Chan G.C.F. and Li C.B., A possible role of IL-17 during Salmonella typhimurium infection, 5th International Human Microbiome Congress. 2015. |
| Sun W., Yang L.H., Lau A.S.Y. and Li C.B., Inhibitory Effect of Panax Notoginseng (PNG) Extracts on the TNF-α-induced MMP-9 Activity in Cardiomyoblasts, 2014 Annual Scientific Meeting, Hong Kong College of Paediatricians. 2014. |
| Researcher : Li WYV |
| List of Research Outputs |
| Li W.Y.V. and Cheung Y.F., Arterial-left ventricular-left atrial coupling late after repair of aortic coarctation and interruption , European Heart Journal - Cardiovascular Imaging . 2015, doi:10.1093/ehjci/jeu309. |
| Li W.Y.V., Chen H.S.R., Wong W.H.S. and Cheung Y.F., Left ventricular cotractile reserve in young adults long-term after repair of coarctation of the aorta , Am J Cardiol . 2015, 115: 348-53. |
| Li W.Y.V. and Cheung Y.F., Right ventricular myocardial motion and deformation in adolescents and young adults after repair of coarctation of the Aorta (doi:10.1111/echo.12868), Echocardiography. 2015, 797-804. |
| Researcher : Ling WL |
| List of Research Outputs |
| Ling W.L., Chan G.C.F. and Li C.B., A possible role of IL-17 during Salmonella typhimurium infection, 5th International Human Microbiome Congress. 2015. |
| Researcher : Liu APY |
| Project Title: | Copy-number variations in Chinese patients with conotruncal defects |
| Investigator(s): | Liu APY, Wong WL, Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2013 |
| Project Title: | Immunogenicity and immunomodulatory activitiy of induced pluripotent stem cells-derived cardiomyocytes from human mesenchymal stem cells |
| Investigator(s): | Liu APY, Poon NYE, Boheler KR, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| List of Research Outputs |
| Leung T.F., Liu A.P.Y., Lim F.S., Thollot F., Oh H.M., Lee B.W., Rombo L., Tan N.C., Rouzier R., Friel D., De Muynck B., De Simoni S., Suryakiran P., Hezareh M., Folschweiller N., Thomas F. and Struyf F., Comparative immunogenicity and safety of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine and HPV-6/11/16/18 vaccine administered according to 2- and 3-dose schedules in girls aged 9-14 years: Results to month 12 from a randomized trial, Hum Vaccin Immunother. 2015, 11(7): 1689-702. |
| Liu A.P.Y., Chan G.C.F., Chung B.H.Y. and So J.C.C., Infant onset pancytopenia: A Case Report of Fanconi Anaemia managed with Matched-Sibling Cord Blood Transplantation (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Liu A.P.Y., Lee V. and Chiang A.K.S., Refractory Acute Lymphoblastic Leukemia in Chinese Children: Bridging to Stem Cell Transplantation with Clofarabine-Based Regimen, 43rd Annual Scientific Meeting, The Hong Kong Society of Haematology, Free paper session. 2015. |
| Liu A.P.Y., Chang K.O., Au Yeung K.H.R., Chan A. and Chan G.C.F., Succinate Dehydrogenase Subunit B (sdhb) Gene Mutations In Paediatric Metastatic Paraganglioma: A Report Of Two Cases, Hong Kong College of Paediatricians Annual Scientific Meeting 2014. |
| Liu A.P.Y., 兒童癌症存活率達七成, 醫健寶庫, 2014. |
| Researcher : Liu H |
| List of Research Outputs |
| Liu H., SO J., TSANG K.H., Mak H.S. and Chan S.Y., A novel role of nucleosome assembly protein in histone modification, Stem Cells and Epigenetics in Cancer, HK, 16-18 October 2014. |
| Researcher : Liu Y |
| List of Research Outputs |
| ROBLES J.D., Liu Y., CAO J., XIANG Z. and Chan G.C.F., Immunosuppressive mechanisms of human bone marrow derived mesenchymal stromal cells in BALB/c host graft versus host disease murine models, Exp Hematol Oncol. 2015. |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |
| Researcher : Low LCK |
| Project Title: | 12th Asia Pacific Congress of Paediatrics and 2nd Asia Pacific Congress of Paediatric Nursing The Role of Nutritional Intake and Total Energy Expenditure on Early Growth of Babies Born with Intrauterine Growth Retardation |
| Investigator(s): | Low LCK |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2006 |
| Researcher : Luk HM |
| List of Research Outputs |
| Chonufani S., Cytrynbaum C., Chung B.H.Y., Turinsky A.L., Grafodatskaya D., Chen Y.A., Luk H.M., Lo I.F.M., Lam S.T.S., Stavropoulos D.J., Gibson B., Reardon M., Brudno M., Mendoza-Londono R., Chitayat D. and Weksberg R., NSD1+/- DNA methylation (DNAm) signature: A novel functional diagnostic tool for Sotos syndrome, 64th American Society of Human Genetics Annual Meeting (ASHG) 2014, San Digeo, USA, 18-22 October 2014. |
| Mok T.K.G., Luk H.M., Chu W.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics, new series. 2014, 19: 265. |
| YEUNG K.S., Chee W.Y.Y., Luk H.M., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Shuen A.Y., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Spread of X Inactivation on Chromosome 15 is Associated with a More Severe Phenotype in a Girl with an Unbalanced t(X;15) Translocation, American Journal of Medical Genetics (Part A). 2014, 164(10): 2521-2528. |
| Researcher : MAK CCY |
| List of Research Outputs |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| MAK C.C.Y., Chow P.C., Chau A.K.T., Chan Y.K., Bassett A.S. and Chung B.H.Y., Clinical implications of large rare copy number variations in 110 Chinese patients with conotruncal heart disease (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Researcher : Mak CCY |
| List of Research Outputs |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| MAK C.C.Y., Chow P.C., Chau A.K.T., Chan Y.K., Bassett A.S. and Chung B.H.Y., Clinical implications of large rare copy number variations in 110 Chinese patients with conotruncal heart disease (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Researcher : Mak HS |
| List of Research Outputs |
| CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., A mouse model of emotional dysregulation with deficiency in LRRC7, 19th Research Postgraduate Symposium, 10-11 December 2014. |
| CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., A mouse model of emotional dysregulation with deficiency in LRRC7, 50th Anniversary Golden Jubilee Scientific Meeting, 29-30 November 2014. |
| Liu H., SO J., TSANG K.H., Mak H.S. and Chan S.Y., A novel role of nucleosome assembly protein in histone modification, Stem Cells and Epigenetics in Cancer, HK, 16-18 October 2014. |
| Researcher : Mok TKG |
| List of Research Outputs |
| Mok T.K.G., Chu W.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics. Medcom Limited, 2015, 20(2): 118-119. |
| Mok T.K.G., Chiang J.P.W., Yeung J.C.C. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2014, 19(3): 207. |
| Mok T.K.G., Luk H.M., Chu W.Y. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis?, Hong Kong Journal of Paediatrics, new series. 2014, 19: 265. |
| Mok T.K.G., Ng G.H.T., Kwok M.K.A. and Chung B.H.Y., What is the Diagnosis?, Hong Kong Journal of Paediatrics (new series). 2015, 20: 41-42. |
| Mok W.K.Y., Wong W.H.S., Mok T.K.G., Chu W.Y., HO K.W., Chow C.B., Ip P. and Chung B.H.Y., Validation and application of health utilities index in Chinese subjects with Down Syndrome, Health and Quality of Life Outcomes. 2014, 12(1): 144. |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| Researcher : NG CP |
| List of Research Outputs |
| CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., A mouse model of emotional dysregulation with deficiency in LRRC7, 19th Research Postgraduate Symposium, 10-11 December 2014. |
| CHONG C.H., NG C.P., Li Q., Mak H.S., McAlonan G.M. and Chan S.Y., A mouse model of emotional dysregulation with deficiency in LRRC7, 50th Anniversary Golden Jubilee Scientific Meeting, 29-30 November 2014. |
| Researcher : NING J |
| List of Research Outputs |
| Chiang A.K.S., NING J. and Chan K.H., Emergence of highly functional antigen-specific T cells towards Epstein-Barr virus corresponds to viral control and enhanced cytotoxicity in children with infectous mononucleosis and primary asymptomatic infection, 16th International Symposium on EBV and Associated Diseases. 2014. |
| WONG A.M.G., NING J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric liver transplant recipients who developed post-transpleant lymphoproliferative disorder, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Wong A.M.G., Ning J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr Virus in paediatric liver translplant recipients who developed post-transplant lymphoproliferative disorder, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong, . 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder. , Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder, 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : Ning J |
| List of Research Outputs |
| Chiang A.K.S., NING J. and Chan K.H., Emergence of highly functional antigen-specific T cells towards Epstein-Barr virus corresponds to viral control and enhanced cytotoxicity in children with infectous mononucleosis and primary asymptomatic infection, 16th International Symposium on EBV and Associated Diseases. 2014. |
| WONG A.M.G., NING J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric liver transplant recipients who developed post-transpleant lymphoproliferative disorder, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Wong A.M.G., Ning J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr Virus in paediatric liver translplant recipients who developed post-transplant lymphoproliferative disorder, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong, . 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder. , Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder, 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : PEI LCS |
| List of Research Outputs |
| PEI L.C.S., Wu Y., Lau Y.L. and Lee P.P.W., Possible role(s) of interferon regulation of inflammasome activity via autophagy (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Researcher : ROBLES JD |
| List of Research Outputs |
| ROBLES J.D., Liu Y., CAO J., XIANG Z. and Chan G.C.F., Immunosuppressive mechanisms of human bone marrow derived mesenchymal stromal cells in BALB/c host graft versus host disease murine models, Exp Hematol Oncol. 2015. |
| Researcher : SHEN J |
| List of Research Outputs |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : SO J |
| List of Research Outputs |
| Liu H., SO J., TSANG K.H., Mak H.S. and Chan S.Y., A novel role of nucleosome assembly protein in histone modification, Stem Cells and Epigenetics in Cancer, HK, 16-18 October 2014. |
| Researcher : Shen JJ |
| List of Research Outputs |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Researcher : So LY |
| List of Research Outputs |
| Chiu S.S.S., Ho P.L., Khong P.L., Ooi C.G.C., So L.Y., Wong W.H.S. and Chan L.Y., Population-based incidence of community-acquired pneumonia hospitalization in Hong Kong children younger than 5 years before universal conjugate pneumococcal immunization. , Journal of Microbiology, Immunology and Infection. 2014. |
| Researcher : TSANG KH |
| List of Research Outputs |
| Liu H., SO J., TSANG K.H., Mak H.S. and Chan S.Y., A novel role of nucleosome assembly protein in histone modification, Stem Cells and Epigenetics in Cancer, HK, 16-18 October 2014. |
| Researcher : Tan TY |
| List of Research Outputs |
| Fung G.P.C., Chu W.Y., Chan H.B., Oufadem M., Amiel J., Gordon C.T., Chung B.H.Y. and Tan T.Y., Mandibulofacial dysostosis with microcephaly caused by a novel "EFTUD2" mutation in a Chinese infant (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| Researcher : Tao QV |
| List of Research Outputs |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| Researcher : Tso WWY |
| Project Title: | Genetic basis of autism and macrocephaly |
| Investigator(s): | Tso WYW, Wong VCN, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2012 |
| List of Research Outputs |
| Researcher : Tso WYW |
| Project Title: | Genetic basis of autism and macrocephaly |
| Investigator(s): | Tso WYW, Wong VCN, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2012 |
| List of Research Outputs |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| Tso W.Y.W., Wong V.C.N., Ao L.J., Li M., Zhang X., Jiao F.Y., Xu X., Du K.X., Faragher B., Xia X.L. and Challis D., Griffiths Mental Developmental Scales (GMDS) validation in China , The British Paediatric Neurology Association. The Sage Newcastle Gateshead. 21-23 January 2015. |
| Researcher : Tu W |
| Project Title: | Humanized mouse as a model to study the antiviral activity of human gammadelta-T cells against human and avian influenza A viruses in vivo |
| Investigator(s): | Tu W, Lau YL, Peiris JSM, Law HKW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 08/2007 |
| Project Title: | Antiviral Activity of Human gammadelta-T Cells against Epstein-Barr Virus Infection |
| Investigator(s): | Tu W, Lau YL, Liu Y, Tsao GSW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2011 |
| Completion Date: | 09/2014 |
| Project Title: | Induction of tolerance by alloantigen-specific regulatory T cells in humanized mice and non-human primates |
| Investigator(s): | Tu W, Lau YL, Liu Y |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2012 |
| Project Title: | Role of human gammadelta-T cells in the generation of influenza virus-specific antibody |
| Investigator(s): | Tu W, Lau YL, Liu Y |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 11/2013 |
| Project Title: | Antiviral Activity of Human γδ-T cells against Enterovirus 71 |
| Investigator(s): | Tu W, Lau YL, Liu Y, Zheng J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 01/2014 |
| Project Title: | Interaction between human NK cells and other immune cells and its effects on the fate decision of NK cells during influenza virus infection. |
| Investigator(s): | Tu W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| Completion Date: | 05/2015 |
| Project Title: | Human gammadelta-T cell-mediated virus-specific immune regulation during influenza virus infection |
| Investigator(s): | Tu W, Lau YL, Liu Y, Zheng J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| List of Research Outputs |
| LIU M., REN D., Zheng J. and Tu W., Stem cell and Idiopathic pulmonary fibrosis: mechanisms and treatment, current stem cell research & therapy. 2015. |
| Lu Q., Yu M., Shen C., Chen X., Feng T., Yao Y., LI J., Li H. and Tu W., Negligible immunogenicity of induced pluripotent stem cells derived from human skin fibroblasts, PLOS One. 2014, 11(9): e114949. |
| Qi X., Ng K.T.P., Lian Q., Liu X., Li C., Ma Y.Y., Yeung W.H., Tu W., Fan S.T., Lo C.M. and Man K., Clinical significance and therapeutic value of glutathione peroxidase 3 (GPx3) in hepatocellular carcinoma, Oncotarget. 2014, Epub on 2014-10-11. |
| Tang W., An Y., Dai R., Wang Q., Jiang L., Tang X., Yang X., Yu J.I.E., Tu W. and Zhao X., Clinical, molecular, and T cell subset analyses in a small cohort of Chinese patients with hyper-IgM syndrome type 1, Human Immunology. 2014, 75: 633-640. |
| Tu W., Lau Y.L. and Peiris J.S.M., Use of humanised mice to study antiviral activity of human γδ-T cells against influenza A viruses, Hong Kong Medical Journal. 2014, 20(Suppl 6): S4-6. |
| Wu J., Liu D., Tu W., Song W. and Zhao X., T-cell receptor diversity is selectively skewed in T-cell populations of patients with Wiskott-Aldrich syndrome, Journal of Allergy and Clinical Immunology. 2014. |
| Wu Y., Tu W., Lam K.T., Chow K.H., Ho P.L., Guan Y., Peiris J.S.M. and Lau Y.L., Lethal coinfection of influenza virus and Streptococcus pneumoniae lowers antibody response to influenza virus in lung and reduces numbers of germinal center B cells, T follicular helper cells, and plasma cells in mediastinal lymph Node., Journal of Virology. 2015, 89(4): 2013-23. |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |
| Researcher : WANG T |
| List of Research Outputs |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Researcher : WANG Y |
| List of Research Outputs |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : WONG AMG |
| List of Research Outputs |
| WONG A.M.G., NING J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric liver transplant recipients who developed post-transpleant lymphoproliferative disorder, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Wong A.M.G., Ning J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr Virus in paediatric liver translplant recipients who developed post-transplant lymphoproliferative disorder, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong, . 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder. , Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder, 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : Wang Y |
| List of Research Outputs |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Wong AMG |
| List of Research Outputs |
| WONG A.M.G., NING J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric liver transplant recipients who developed post-transpleant lymphoproliferative disorder, 16th International Symposium on EBV and Associated Diseases. 2014. |
| Wong A.M.G., Ning J., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr Virus in paediatric liver translplant recipients who developed post-transplant lymphoproliferative disorder, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong, . 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder. , Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Wong A.M.G., Ning J., Kwok H., Chan K.H. and Chiang A.K.S., Longitudinal study of viral loads and polyfunctional T cell responses towards Epstein-Barr virus in paediatric patients with post-transplant lymphoproliferative disorder, 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : Wong KY |
| List of Research Outputs |
| Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Researcher : Wong RSM |
| List of Research Outputs |
| Abraham A., Wong W.H.S., Lee A., Louie L.H.T., Nelson E.A.S., Ho K.W., So H.K., Wong R.S.M., Yu C., Cheung T.K., Yue S.K., Lam S.F., Chow W.C., Chow C.B. and Ip P., Promoting Physical Activity among Adolescents in Hong Kong, Hong Kong College of Paediatricans, Annual Scientific Meeting, 6 December 2014. |
| Ip P., Wong R.S.M., Li S.L., Chan E.K.L., Ho F...K... and Chow C.B., Mental Health Consequences of Childhood Physical Abuse in Chinese Populations: A Meta-analysis. Trauma, Violence, & Abuse, 2015. |
| Researcher : Wong SN |
| List of Research Outputs |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Wong VCN |
| Project Title: | Rett Syndrome :Systematic screening of MECP2 in children with autistic traits and or unexplained mental retardation/ encephalopathy to define the spectrum of Rett Syndrome phenotypes resulting from mutations in MECP2 |
| Investigator(s): | Wong VCN |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2006 |
| Project Title: | Genetic analysis of PCDH19 and TSPYL mutation in Chinese children with GEFS+ and Dravet Syndromeencephaolpathy |
| Investigator(s): | Wong VCN, Kwong KY, Fung CW, Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2012 |
| Completion Date: | 05/2015 |
| Project Title: | Mutation analysis of CDKL5, STXBP1 and GABA receptor subunit genes in Chinese children with infantile spasms (IS) |
| Investigator(s): | Wong VCN, Kwong KY, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2013 |
| Completion Date: | 05/2016 |
| Project Title: | A study of copy number variations (CNVs) of genes NRXN1, GRIN2A, GRIN2B and PCDH19 associated with synaptic function in Chinese children with infantile epileptic encephalopathies |
| Investigator(s): | Wong VCN, Kwong KY, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Project Title: | Investigation of causal mutations by whole exome sequencing (WES) in Chinese children with infantile epileptic encephalopathy (IEE) |
| Investigator(s): | Wong VCN, Kwong KY, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2015 |
| Completion Date: | 04/2018 |
| Project Title: | 13th Asian and Oceanian Congress of Child Neurology (2015 AOCCN); Chair Session: Behavioral Medicine |
| Investigator(s): | Wong VCN |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 05/2015 |
| Completion Date: | 05/2015 |
| List of Research Outputs |
| Du R.Y., Yiu C.K.Y., King N.M., Wong V.C.N. and McGrath C.P.J., Oral health among preschool children with autism spectrum disorders: A case-control study, Autism: the international journal of research and practice. 2014. |
| Du Y.R., Yiu C.K.Y., Wong V.C.N. and McGrath C.P.J., Autism Developmental Profiles and Cooperation with Oral Health Screening, Journal of Autism and Developmental Disorders. 2015, 45: 2758-63. |
| Santos D., Pimenta J., Wong V.C.N., Amorim A. and Martins S., Diversity in the Androgen Receptor CAG repeat has been shaped by a multistep mutational mechanism. (Epub ahead print) , In: Neuropsychiatric Genetics, 2014. |
| Tso W.Y.W., Wong V.C.N., Ao L.J., Li M., Zhang X., Jiao F.Y., Xu X., Du K.X., Faragher B., Xia X.L. and Challis D., Griffiths Mental Developmental Scales (GMDS) validation in China , The British Paediatric Neurology Association. The Sage Newcastle Gateshead. 21-23 January 2015. |
| Wong V.C.N., Editorial Board Member (Since 2001), Pediatrics International. 2014. |
| Wong V.C.N., Sun J.G. and Yeung D.W.C., Randomized control trial of using tongue acupuncture in autism spectrum disorder, Journal of Traditional Chinese Medical Sciences. 2014, 1: 62-72. |
| Wong V.C.N., Reviewer (Since 1987), Brain & Development. 2014. |
| Researcher : Wong WHS |
| List of Research Outputs |
| Abraham A., Wong W.H.S., Lee A., Louie L.H.T., Nelson E.A.S., Ho K.W., So H.K., Wong R.S.M., Yu C., Cheung T.K., Yue S.K., Lam S.F., Chow W.C., Chow C.B. and Ip P., Promoting Physical Activity among Adolescents in Hong Kong, Hong Kong College of Paediatricans, Annual Scientific Meeting, 6 December 2014. |
| Chiu S.S.S., Ho P.L., Khong P.L., Ooi C.G.C., So L.Y., Wong W.H.S. and Chan L.Y., Population-based incidence of community-acquired pneumonia hospitalization in Hong Kong children younger than 5 years before universal conjugate pneumococcal immunization. , Journal of Microbiology, Immunology and Infection. 2014. |
| Ho F...K...W., Louie L...H...T., Chow C.B., Wong W.H.S. and Ip P., Physical activity improves mental health through resilience in Hong Kong Chinese adolescents BMC Pediatrics, 2015. |
| Lam H.W., Chan G.C.F., Marcet M.M., Wong W.H.S., Wong J. and Wong D.S.H., Spontaneous Self-Concept Among Chinese University Undergraduates in Hong Kong, Social Behavior and Personality. 2014. |
| Li W.Y.V., Chen H.S.R., Wong W.H.S. and Cheung Y.F., Left ventricular cotractile reserve in young adults long-term after repair of coarctation of the aorta , Am J Cardiol . 2015, 115: 348-53. |
| Man K.C.K., Ip P., Hsia Y., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A.W.Y. and Wong I.C.K., ADHD Drug Prescribing Trend Is Increasing Among Children and Adolescents in Hong Kong, Journal of Attention Disorders published online 3 July 2014. 2014. |
| Man K.C.K., Chan E.W., Douglas I., Ip P., Wong W.H.S., Coghill D. and Wong I.C.K., Attention-Deficit/Hyperactivity Disorder (ADHD) Pharmacological Treatment and Its Effect on Accident and Emergency Admission Due to Injury: A Self-Controlled Case-Series Study, 30th International Conference for Pharmacoepidemiology (ICPE). 2014. |
| Man K.C.K., Chan E.W., Coghill D., Douglas I., Ip P., Leung L.P., Tsui M.S.H., Wong W.H.S. and Wong I.C.K., Methylphenidate and the Risk of Trauma, PEDIATRICS. 2014, 135(1): 40-48. |
| Mok W.K.Y., Wong W.H.S., Mok T.K.G., Chu W.Y., HO K.W., Chow C.B., Ip P. and Chung B.H.Y., Validation and application of health utilities index in Chinese subjects with Down Syndrome, Health and Quality of Life Outcomes. 2014, 12(1): 144. |
| Wong W.H.S. and Chiu I.W.S., The Impact of Habit of Eating Breakfast and Physical Activity on Children Suicidal Behaviour, International Journal of Behavioral Research & Psychology. SciDoc, 2015, 3(4): 99-104. |
| Wong W.H.S., Li S.L., Fu K.W., Tinsley H.M., Chow C.B. and Ip P., The importance of online resources for parents of children with special needs in Hong Kong: South China's experience. Journal of Health and Medical Informatics, 2015. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Wong WL |
| List of Research Outputs |
| LEUNG K.C., Ma C.H., Gao W., Chu W.Y., Wong W.L., Jin D., Lo I.F.M., Luk H.M. and Chung B.H.Y., Contribution of gain-of-function mutations in R1T1 to the pathogenesis of Noonan syndrome - A report of 3 new Chinese patients in Hong Kong (1st runner-up prize of best oral presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| YEUNG K.S., LEUNG K.C., Wong W.L., Li R.C.H., Choi K.Y., Kuong E.Y.L., Chow W., To M., Chan G.C.F. and Chung B.H.Y., Somatic Mosicism of PIK3CA mutation In PIK3CA-related overgrowth disorders (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Researcher : Wu Y |
| List of Research Outputs |
| PEI L.C.S., Wu Y., Lau Y.L. and Lee P.P.W., Possible role(s) of interferon regulation of inflammasome activity via autophagy (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| Wu Y., Tu W., Lam K.T., Chow K.H., Ho P.L., Guan Y., Peiris J.S.M. and Lau Y.L., Lethal coinfection of influenza virus and Streptococcus pneumoniae lowers antibody response to influenza virus in lung and reduces numbers of germinal center B cells, T follicular helper cells, and plasma cells in mediastinal lymph Node., Journal of Virology. 2015, 89(4): 2013-23. |
| Researcher : XIANG Z |
| List of Research Outputs |
| ROBLES J.D., Liu Y., CAO J., XIANG Z. and Chan G.C.F., Immunosuppressive mechanisms of human bone marrow derived mesenchymal stromal cells in BALB/c host graft versus host disease murine models, Exp Hematol Oncol. 2015. |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |
| Researcher : YEUNG KS |
| List of Research Outputs |
| Wong W.L., Chu W.Y., YEUNG K.S., MAK C.C.Y., Wong K.Y., Li R.H.W., Tang M.H.Y. and Chung B.H.Y., Identification of epigenetic alterations in imprinting growth disorders (poster presentation), 50th Anniversary Scientific Meeting, Dept of Paed & Adol Med, HKU, 29-30 November 2014. |
| YEUNG K.S., LEUNG K.C., Wong W.L., Li R.C.H., Choi K.Y., Kuong E.Y.L., Chow W., To M., Chan G.C.F. and Chung B.H.Y., Somatic Mosicism of PIK3CA mutation In PIK3CA-related overgrowth disorders (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| YEUNG K.S., Chee W.Y.Y., Luk H.M., Kan S.Y.A., Tang M.H.Y., Lau E.T.K., Shuen A.Y., Lo I.F.M., Chan Y.K. and Chung B.H.Y., Spread of X Inactivation on Chromosome 15 is Associated with a More Severe Phenotype in a Girl with an Unbalanced t(X;15) Translocation, American Journal of Medical Genetics (Part A). 2014, 164(10): 2521-2528. |
| Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality – A new condition identified by exome sequencing? , Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 206. |
| Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014. |
| Researcher : YEUNG PL |
| List of Research Outputs |
| Chiang A.K.S., YEUNG P.L. and Hui K.F., Targeting EBV in EBV-associated malignancies, Keystone Symposia Conference – Viruses and Human Cancer, Montana, USA. 2015. |
| Hui K.F., CHOI C.K., YEUNG P.L., Cheung A.K., Middeldorp J.M., Lung M.L., Tsao G.S.W. and Chiang A.K.S., A potent class I histone deacetylase inhibitor romidepsin induced lytic cycle of Epstein-Barr virus (EBV) in EBV-positive epithelial malignancies, Golden Jubilee Scientific Meeting (Oral Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., YEUNG P.L. and Chiang A.K.S., Bortezomib synergizes with romidepsin to induce apoptosis and autophagy in gastric carcinoma cells in vitro and in vivo, Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., YEUNG P.L., Middeldorp J.M. and Chiang A.K.S., Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines, Br J Haematol.. John Wiley & Sons Ltd., 2014, 167(5): 639-50. |
| Hui K.F., CHOI C.K., YEUNG P.L., Middeldorp J.M., Tsao G.S.W. and Chiang A.K.S., Inhibition of class I Histone Deacetylases (HDACs) by HDAC inhibitors leads to the induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-positive epithelial malignancies, 21st Hong Kong International Cancer Congress, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Hui K.F., CHOI C.K., YEUNG P.L., MIDDELDORP J.M., Tsao G.S.W. and Chiang A.K.S., Inhibition of class I histone deacetylases (HDACs) by HDAC inhibitiors leads to the induction of Epstein-Barr virus (EBV) lytic cycle in EBV-positive epithelial malignancies, 16th International Symposium on EBV and Associated Diseases. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates P16INK4A and P21WAF1 and induces apoptosis of EBV-Transformed lymphoblastoid cell lines, 21st Hong Kong International Cancer Congress, LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates P16INK4A and P21WAF1 and induces apoptosis of EBV-Transformed lymphoblastoid cell lines, The Hong Kong Paediatric Society and Hong Kong Paediatric Nurses Association Ltd Joint Annual Scientific Meeting 2014. 2015. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of HDAC and proteasome inhibitors up-regulates p16INK4A and p21WAF1 and induces apoptosis of EBV-transformed lymphoblastoid cell lines, 16th International Symposium on EBV and Associated Diseases. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of histone deacetylase and proteasome inhibitors induces synergistic killing of Epstein-Barr virus-transformed lymphoblastoid cell lines through counteracting the anti-apoptotic mechanism of EBNA-3 proteins , 19th Research Postgraduate Symposium (Poster Presentation), LKS Faculty of Medicine, The University of Hong Kong. 2014. |
| YEUNG P.L., Hui K.F., LEUNG Y.Y. and Chiang A.K.S., Combination of histone deacetylase and proteasome inhibitors induces synergistic killing of Epstein-Barr virus-transformed lymphoblastoid cell lines through counteracting the anti-apoptotic mechanism of EBNA-3 proteins, Golden Jubilee Scientific Meeting (Poster Abstract Presentation), Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2014. |
| Researcher : Yang J |
| List of Research Outputs |
| HUANG Y., Yang J., Ying D., Zhang Y., Shotelersuk V., Hirankarn N., Sham P.C., Lau Y.L. and Yang W., HLAreporter: a tool for HLA typing from next generation sequencing data, Genome Medicine. 2015, 7(1): 25. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Yang LH |
| List of Research Outputs |
| Sun W., Yang L.H., Lau A.S.Y. and Li C.B., Inhibitory Effect of Panax Notoginseng (PNG) Extracts on the TNF-α-induced MMP-9 Activity in Cardiomyoblasts, 2014 Annual Scientific Meeting, Hong Kong College of Paediatricians. 2014. |
| Researcher : Yang M |
| Project Title: | Protective effect of thrombopoietin on iron-induced cardiomyopathy |
| Investigator(s): | Yang M |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 07/2007 |
| Project Title: | The effect of melatonin in the treatment of thrombocytopenia |
| Investigator(s): | Yang M |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme |
| Start Date: | 01/2008 |
| Project Title: | The protective effects of thrombopoietin and amlodipine on iron overload-induced human mesenchymal stem cell damage: its impact on iron overload related osteopenia & osteoporosis |
| Investigator(s): | Yang M, Chan GCF, Cheung YF, Liu C |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 01/2009 |
| Researcher : Yang W |
| Project Title: | Meta-Analysis of two Asian GWAS datasets for identification of novel genetic variants associated with systemic lupus erythematosus |
| Investigator(s): | Yang W, Lau YL, Sham PC, Yang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2011 |
| Project Title: | Identifying susceptibility genes in the human MHC region independently associated with systemic lupus erythematosus (SLE) in Chinese populations |
| Investigator(s): | Yang W, Lau YL, Sham PC |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Project Title: | Molecular diagnosis for severe combined immunodeficiencies (SCID) using whole exome sequencing |
| Investigator(s): | Yang W, Lau YL, Lee PPW, Chung BHY, Yang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | Development of a database on genetic variants found by Whole Exome Sequencing to aid variant filtering and prioritization in genetic studies |
| Investigator(s): | Yang W, Ying D, Yang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| Project Title: | Meta-Analysis of three GWAS datasets from Hong Kong, Anhui China and UK followed by replication in independent cohorts in Asia and UK for identification of novel susceptibility genes associated with SLE |
| Investigator(s): | Yang W, Sham PC, Lau YL, Yang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2014 |
| Project Title: | American Society of Human Genetics Annual Meeting 2014; Genetic testing of targeted genes using next generation sequencing on PCR amplicons |
| Investigator(s): | Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2014 |
| Completion Date: | 10/2014 |
| Project Title: | Haplotype-based analysis of genome-wide association study data to uncover genes associated with SLE in Hong Kong and other Asian populations |
| Investigator(s): | Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2015 |
| List of Research Outputs |
| Anney R.J.L., Avbersek A., Balding D., Baum L., Becker F., Berkovic S.F., Bradfield J.P., Lau Y.L., Yang W. and Cherny S.S., Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies, The Lancet Neurology. 2014, 13: 893-903. |
| HUANG Y., Yang J., Ying D., Zhang Y., Shotelersuk V., Hirankarn N., Sham P.C., Lau Y.L. and Yang W., HLAreporter: a tool for HLA typing from next generation sequencing data, Genome Medicine. 2015, 7(1): 25. |
| Jiang S., Yang W., Qiu Y. and Chen H.Z., Alzheimer's Disease Neuroimaging Initiative (ADNI). Identification of novel quantitative traits-associated susceptibility loci for APOE ε 4 non-carriers of Alzheimer's disease, Current Alzheimer Research. Bentham Science Publishers, 2015, 12(3): 218-227. |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| LI J., Deng S.J., WANG P., Yang W., Ho S.L., Sham P.C., Wang J.J. and Li M., wKGGSeq: A Comprehensive Strategy-Based and Disease-Targeted Online Framework to Facilitate Exome Sequencing Studies of Inherited Disorders, Human Mutation. 2015, 36: 496-503. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| TAM C.Y., Yang W., Lau W.C.S. and Chan V.S.F., Systemic Lupus Erythematosus Patients Exhibit Reduced Expression of CLEC16A Isoforms in Peripheral Leukocytes, International Journal of Molecular Sciences. Basel, Switzerland, MDPI AG, 2015, 16: 14428-14440. |
| Tao Q.V., Chan Y.K., Chu W.Y., Mok T.K.G., Tan T.Y., Yang W., Lee S.L., Tang W.F., Tso W.Y.W., Lau E.T.K., Kan S.Y.A., Tang M.H.Y., Lau Y.L. and Chung B.H.Y., The clinical impact of chromosomal microarray on paediatric care in Hong Kong, PLOS One. 2014, 9(10): e:109629. |
| WANG P., Siu K.L., Zhang Y., Yang W., Kok K.H. and Jin D., IFI16β and STINGβ: Negative Regulators of Innate Immunity Generated by Alternative Splicing, 19th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, December 10 & 11, 2014. |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| Ying D., Sham P.C., Smith D.K., ZHANG L., Lau Y.L. and Yang W., HaploShare: identification of extended haplotypes shared by cases and evaluation against controls, Genome Biology. 2015, 16: 92. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Zhou X.J., Nath S.K., Qi Y.Y., Cheng F.J., Yang H.Z., Zhang Y., Yang W., Ma J.Y., Zhao M.H., Shen N. and Zhang H., Brief Report: identification of MTMR3 as a novel susceptibility gene for lupus nephritis in northern Han Chinese by shared-gene analysis with IgA nephropathy, Arthritis Rheumatol. 2014, 66(10): 2842-2848. |
| Researcher : Yick LW |
| Project Title: | Defining the roles of epidermal growth factor (EGF) in the regulation of chondrocyte differentiation and endochondral bone formation |
| Investigator(s): | Yick LW, Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Researcher : Ying D |
| List of Research Outputs |
| HUANG Y., Yang J., Ying D., Zhang Y., Shotelersuk V., Hirankarn N., Sham P.C., Lau Y.L. and Yang W., HLAreporter: a tool for HLA typing from next generation sequencing data, Genome Medicine. 2015, 7(1): 25. |
| LEUNG K.C., MAK C.C.Y., Chen Y.X., Chau C.S.K., Ying D., Chu W.Y., Li A.M., Yang W., Lau Y.L., chan K.Y.K., Chen J.H., Lee S.L. and Chung B.H.Y., CFTR: I1023R is a rare but recurrent disease-causing mutation found in Chinese patients with cystic fibrosis (outstanding oral presentation), HKCP Annual Scientific Meeting, 6 December 2014. |
| Mak C.C.Y., Ying D., LEUNG K.C., Lee P.P.W., Yang J., Yang W., Chung B.H.Y. and Lau Y.L., The Application of Whole-Exome Sequencing in Diagnosis Pediatric Rare Disease in Hong Kong, North American Journal of Medicine and Science. 2014, 7(4): 139-147. |
| Yang W., Lee P.P.W., Thong M.K., Ramanujam T.M., Shanmugam A., Koh M.T., Chan K.W., Ying D., Wang Y., SHEN J., Yang J. and Lau Y.L., Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency, Clinical Genetics. Wiley Publisher, 2015. |
| Ying D., Sham P.C., Smith D.K., ZHANG L., Lau Y.L. and Yang W., HaploShare: identification of extended haplotypes shared by cases and evaluation against controls, Genome Biology. 2015, 16: 92. |
| Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality – A new condition identified by exome sequencing? , Hong Kong Journal of Paediatrics (new series) [Proceedings for Joint Annual Scientific Meeting 2014: HK Paediatric Society and HK Paediatric Nurses Association], 15 June 2014. 2014, 19(3): 206. |
| Ying D., Shek N.W.M., Chu W.Y., YEUNG K.S., Leung K.C., Tang M.H.Y., Kan S.Y.A., Chan Y.K. and Chung B.H.Y., Homozygous missense mutation in ABR causes cerebellar hypoplasia with early lethality - A new condition identified by exome sequencing?, 35th Annual David W. Smith - Workshop on Malformations and Morphogenesis, The Fluno Center, University of Wisconsin, USA, 25-30 July 2014. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Researcher : Yung AWY |
| List of Research Outputs |
| Man K.C.K., Ip P., Hsia Y., Chan E.W., Chui S.L.C., Lam M.P.S., Wong W.H.S., Chow C.B., Yung A.W.Y. and Wong I.C.K., ADHD Drug Prescribing Trend Is Increasing Among Children and Adolescents in Hong Kong, Journal of Attention Disorders published online 3 July 2014. 2014. |
| Researcher : ZENG S |
| List of Research Outputs |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| Researcher : ZHANG J |
| List of Research Outputs |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : ZHANG L |
| List of Research Outputs |
| Ying D., Sham P.C., Smith D.K., ZHANG L., Lau Y.L. and Yang W., HaploShare: identification of extended haplotypes shared by cases and evaluation against controls, Genome Biology. 2015, 16: 92. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : ZHANG Y |
| List of Research Outputs |
| HUANG Y., Yang J., Ying D., Zhang Y., Shotelersuk V., Hirankarn N., Sham P.C., Lau Y.L. and Yang W., HLAreporter: a tool for HLA typing from next generation sequencing data, Genome Medicine. 2015, 7(1): 25. |
| WANG P., Siu K.L., Zhang Y., Yang W., Kok K.H. and Jin D., IFI16β and STINGβ: Negative Regulators of Innate Immunity Generated by Alternative Splicing, 19th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, December 10 & 11, 2014. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Zhou X.J., Nath S.K., Qi Y.Y., Cheng F.J., Yang H.Z., Zhang Y., Yang W., Ma J.Y., Zhao M.H., Shen N. and Zhang H., Brief Report: identification of MTMR3 as a novel susceptibility gene for lupus nephritis in northern Han Chinese by shared-gene analysis with IgA nephropathy, Arthritis Rheumatol. 2014, 66(10): 2842-2848. |
| Researcher : Zhang L |
| List of Research Outputs |
| Ying D., Sham P.C., Smith D.K., ZHANG L., Lau Y.L. and Yang W., HaploShare: identification of extended haplotypes shared by cases and evaluation against controls, Genome Biology. 2015, 16: 92. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Researcher : Zhang Y |
| Project Title: | The ASHG 64th Annual Meeting; Meta-analysis on the 22q11.21 region identifies an autoimmune disease risk allele as associated with systemic lupus erythematosus |
| Investigator(s): | Zhang Y |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2014 |
| Project Title: | Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus |
| Investigator(s): | Zhang Y, Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 02/2015 |
| Project Title: | Meta-analysis of SLE GWAS followed by replication on X chromosome in cross-ethnic populations |
| Investigator(s): | Zhang Y, Yang W, Lau YL, Yang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2015 |
| Project Title: | Annual Clinical Genetics Meeting; Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus |
| Investigator(s): | Zhang Y |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 03/2015 |
| Completion Date: | 03/2015 |
| List of Research Outputs |
| HUANG Y., Yang J., Ying D., Zhang Y., Shotelersuk V., Hirankarn N., Sham P.C., Lau Y.L. and Yang W., HLAreporter: a tool for HLA typing from next generation sequencing data, Genome Medicine. 2015, 7(1): 25. |
| WANG P., Siu K.L., Zhang Y., Yang W., Kok K.H. and Jin D., IFI16β and STINGβ: Negative Regulators of Innate Immunity Generated by Alternative Splicing, 19th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, December 10 & 11, 2014. |
| ZHANG J., Zhang L., ZHANG Y., Yang J., Guo M., Sun L., Pan H.F., Hirankarn N., Ying D., ZENG S., Lee T.L., Lau W.C.S., Chan T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok W.C.L., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.S., Fung S.K.S., Lai W.M., Garcia-Barcelo M.M., Cherny S.S., Sham P.C., Yong C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Gene-based meta-analysis of GWAS data identifies independent SNPs in ANXA6 as associated with SLE in Asian populations, Arthritis & Rheumatology. 2014. |
| ZHANG Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan H.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M., Mok C.C., ZHANG L., WANG Y., Shen J.J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., LI X.P., Avihingsanon Y., Rianthavorn P., SDeekajorndej T., Shotelersuk V., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Sham P.C., Garcia-Barcelo M.M., Cherny S.S., Cui Y., Sham P.C., Yang S., Ye D.Q., Zhang X.J., Lau Y.L. and Yang W., Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations, Annuals of Rheumatic Diseases. 2015. |
| Zhang Y., ZHANG J., Yang J., WANG Y., ZHANG L., Zuo X., Sun L., Pan H.F., Hirankarn N., WANG T., CHEN R., Ying D., Shen J.J., Lee T.L., Lau W.C.S., Chan D.T.M., Leung A.M.H., Mok C.C., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K.C., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K.Y., Fung S.K.S., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Lau Y.L. and Yang W., Meta-analysis of GWAS on two Chinese populations followed by replication identifies novel genetic variants on the X chromosome associated with systemic lupus erythematosus, Human Molecular Genetics. 2015, 24(1): 274-284. |
| Zhang Y., Wang Y., Yang J., ZHANG J., Sun L., Hirankarn N., Pan C.F., Lau W.C.S., Chan T.M., Lee T.L., Leung A.M.H., Mok C.C., ZHANG L., SHEN J., Wong S.N., Lee K.W., Ho M.H.K., Lee P.P.W., Chung B.H.Y., Chong C.Y., Wong R.W.S., Mok T.M.Y., Wong W.H.S., Tong K.L., Tse N.K., Li X.P., Avihingsanon Y., Rianthavorn P., Deekajorndej T., Suphapeetiporn K., Shotelersuk V., Ying S.K., Fung S.K., Lai W.M., Wong C.M., Ng I.O.L., Garcia-Barcelo M.M., Cherny S.S., Tam P.K.H., Sham P.C., Yang S., Ye D.Q., Cui Y., Zhang X.J., Yang W. and Lau Y.L., Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus, Arthritis Research & Therapy. 2015, 17: 67. |
| Zhou X.J., Nath S.K., Qi Y.Y., Cheng F.J., Yang H.Z., Zhang Y., Yang W., Ma J.Y., Zhao M.H., Shen N. and Zhang H., Brief Report: identification of MTMR3 as a novel susceptibility gene for lupus nephritis in northern Han Chinese by shared-gene analysis with IgA nephropathy, Arthritis Rheumatol. 2014, 66(10): 2842-2848. |
| Researcher : Zheng J |
| Project Title: | regulatory roles of human gammadelta-T cells in transplantation |
| Investigator(s): | Zheng J, Tu W, Liu Y, Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Completion Date: | 04/2015 |
| List of Research Outputs |
| LIU M., REN D., Zheng J. and Tu W., Stem cell and Idiopathic pulmonary fibrosis: mechanisms and treatment, current stem cell research & therapy. 2015. |
| XIANG Z., Liu Y., Zheng J., Liu M., LU A., GAO Y., Hu H., Lam K.T., Chan G.C.F., Yang Y., Chen H., Tsao G.S.W., Bonneville M M., Lau Y.L. and Tu W., Targeted Activation of Human Vγ9Vδ2-T Cells Controls Epstein-Barr Virus-Induced B Cell Lymphoproliferative Disease, Cancer Cell. 2014. |