DEPT OF OBSTETRICS & GYNAECOLOGY



Researcher : CAO M
List of Research Outputs

CHENG H.C., Chan R.W.S., CAO M., Ng E.H.Y. and Yeung W.S.B., An investigation of matrix metalloproteinase 3 derived from myometrial cells on endometrial mesenchymal stem-like cells maintenance, 50th Society For The Study Of Reproduction. 2017, 63.


Researcher : CHEN K
List of Research Outputs

CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436.
CHEN K., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness via targeting GRB7, Cancer Research. 2017, 77: LB-324-LB-324.


Researcher : CHEN R
List of Research Outputs

CHEN R., Ngan H.Y.S. and Chan D.W., Targeting lipid metabolism eradicates peritoneal metastases of ovarian cancer, AACR Annual Meeting 2018, April 14-18, 2018 McCormick Place North/South Chicago, Illinois. 2018.
Chan D.W., CHEN R., Yung M.H. and Ngan H.Y.S., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade , Cold Spring Harbour Asia organized "conference on Inflammation: Basic Mechanisms & Relevant Diseases". 2017.
Chan D.W., CHEN R. and Ngan H.Y.S., Targeting lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases of ovarian cancer, Cold Spring Harbour Asia: Cancer & Metabolism. 26-30 March, 2018 Suzhou, China. 2018.


Researcher : CHENG HC
List of Research Outputs

CHENG H.C., Chan R.W.S., CAO M., Ng E.H.Y. and Yeung W.S.B., An investigation of matrix metalloproteinase 3 derived from myometrial cells on endometrial mesenchymal stem-like cells maintenance, 50th Society For The Study Of Reproduction. 2017, 63.


Researcher : Chai J
Project Title:10th RCOG International Scientific Congress A randomized clinical trial comparing the sublingual and buccal routes of administration of misoprostol after mifepristone for medical abortions of up to 63 days gestation
Investigator(s):Chai J
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:06/2012




Researcher : Chan DW
Project Title:The mechanism and significance of ovarian cancer cells in modulating AMPK and TNFkB signaling cascade in omental metastasis
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2015


Project Title:The functional role of Hsa-miR-141 in metastatic progression of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:11/2015


Project Title:Investigation the impact of lipid metabolism in peritoneal metastases of ovarian cancer
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016
Completion Date:03/2018


Project Title:Functional characterization of the MAP30 protein from bitter melon (Momordica chrantia) in combating ovarian cancer oncogenesis and chemoresistance
Investigator(s):Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2016


Project Title:Cancer & Metabolism; Targeting lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases of ovarian cancer
Investigator(s):Chan DW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2018
Completion Date:03/2018


List of Research Outputs

CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436.
CHEN K., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness via targeting GRB7, Cancer Research. 2017, 77: LB-324-LB-324.
CHEN R., Ngan H.Y.S. and Chan D.W., Targeting lipid metabolism eradicates peritoneal metastases of ovarian cancer, AACR Annual Meeting 2018, April 14-18, 2018 McCormick Place North/South Chicago, Illinois. 2018.
Chan D.W., CHEN R., Yung M.H. and Ngan H.Y.S., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade , Cold Spring Harbour Asia organized "conference on Inflammation: Basic Mechanisms & Relevant Diseases". 2017.
Chan D.W., CHEN R. and Ngan H.Y.S., Targeting lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases of ovarian cancer, Cold Spring Harbour Asia: Cancer & Metabolism. 26-30 March, 2018 Suzhou, China. 2018.
LEUNG L.L., Yung M.H., Ngan H.Y.S. and Chan D.W., The secretary miR-141 facilitates ovarian cancer metastasis through reprogramming stromal fibroblast cells in pre-metastatic niches formation, the 25th Biennial Congress of the European Association for Cancer Research (EACR25). 2018.
Leung T.H.Y., Tang W.M., Siu K.Y., Chan D.W., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., HPV-E6 protein enriches the CD55(+) population in cervical cancer cells promoting radio-resistance and cancer aggressiveness, The Journal of Pathology. 2017.
Meng Y., Chen C.W., Yung M.H., Sun W., Sun J., Li Z., Li J., Li Z., Zhou W., Liu S., Cheung A.N.Y., Ngan H.Y.S., Braisted J.C., Kai Y., Peng W., Tzatsos A., Li Y., Dai Z., Zheng W., Chan D.W. and Zhu W., DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer, Cancer Letters. 2018.
Wong J.H., Sze S.C.W., Ng T.B., Cheung R.C.F., Tam C., Zhang K.Y., Dan X., Chan Y.S., Cho W.C.S., Ng C.C.W., Waye M.M.Y., Liang W., Zhang J., Yang J., Ye X., Lin J., Ye X.J., Wang H., Liu F., Chan D.W., Ngan H.Y.S., Sha O., Li G., Tse R., Tse T.K. and Chan H., Apoptosis and anti-cancer drug discovery: the power of medicinal fungi and plants, In: Atta-ur-Rahman, FRS, Current Medicinal Chemistry. Bentham Science, 2017, 24: E-pub Abstract Ahead of Print.
Xiang L., Jiang W., Ye S., He T., Pei X., Li J., Chan D.W., Ngan H.Y.S., Li F., Tao P., Shen X., Zhou X., Wu X., Yang G. and Yang H., ERBB2 mutation: A promising target in non-squamous cervical cancer, Gynecologic Oncology. 2018.
Ying L., Yan F., Meng Q., Yu L., Yuan X., Gantier M.P., Williams B.R., Chan D.W., Shi L., Tu Y., Ni P., Wang X., Chen W., Zang X., Xu D. and Hu Y., PD-L1 expression is a prognostic factor in subgroups of gastric cancer patients stratified according to their levels of CD8 and FOXP3 immune markers, OncoImmunology. Taylor & Francis, 2018, 7: e1433520.
Ying L., Yan F., Meng Q., Yuan X., Liang Y., Williams B.R.G., Chan D.W., Shi L., Tu Y., Ni P., Wang X., Xu D. and Hu Y., Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry, Journal of Translational Medicine. BioMed Central, 2017, 15: 206.
Yung M.H., Ngan H.Y.S. and Chan D.W., Cold Spring Harbour Asia conference on "Inflammation: Basic Mechanisms & Relevant Diseases". 2017.
Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285.
Zhou W., Sun W., Yung M.H., Dai S., Cai Y., Chen C.W., Meng Y., Lee J.B., Braisted J.C., Xu Y., Southall N.T., Shinn P., Huang X., Song Z., Chen X., Kai Y., Cai X., Li Z., Hao Q., Cheung A.N.Y., Ngan H.Y.S., Liu S., Barak S., Hao J., Dai Z., Tzatsos A., Peng W., Pei H., Han Z., Chan D.W., Zheng W. and Zhu W., Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance, Oncogene. 2018.


Researcher : Chan KKL
Project Title:Relationship between placental ratio and placental function
Investigator(s):Chan KKL, Lao THT
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Funding for New Staff
Start Date:01/2003


Project Title:The effect of fulvestrant in epithelial ovarian cancer with differential estrogen receptor status in mice
Investigator(s):Chan KKL, Liu S, Tam KF, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2008


Project Title:Sixth International Symposium on Hormonal Oncogenesis USE OF HIGHLY SELECTIVE ESTROGEN RECEPTOR MODULATORS IN OVARIAN CANCER
Investigator(s):Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2010


Project Title:Hexokinase 2 (HK2) in ovarian cancer tumorigenesis and metastasis
Investigator(s):Chan KKL, Ngan HYS, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2016
Completion Date:02/2018


Project Title:Roles of Soy Isoflavones on metastasis and CSCs regulation in ovarian cancer
Investigator(s):Chan KKL, Ngan HYS, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2017


Project Title:Role of miR-16-5p/PDK4 in ovarian cancer
Investigator(s):Chan KKL, Ngan HYS, Leung THY, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2018


Project Title:The use of a new biomarker, HE4, in combination with simple ultrasound rules in the prediction of malignancy in a pelvic mass detected on ultrasound
Investigator(s):Chan KKL, Ngan HYS, Cheung VYT, Tse KY, Chu MYM, Siu KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:06/2018


List of Research Outputs

CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436.
Chan K.K., Wong G.W., Wong E.S.Y., Chan K.K.L., Ip P.C.P., Tse K.Y. and Cheung A.N.Y., Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma, International Journal of Cancer. 2018.
Chan K.K.L., Activities Against Cervical Cancer In Hong Kong, Asia-Oceania Research Organisation in Genital Infection and Neoplasia (“AOGIN”) 2017 Congress , Tokyo, Japan, October 18-19. 2017. 2017.
Chan K.K.L., Case Sharing- use of PARP-I for Ovarian Cancer, International Society of Precision Cancer Medicine ( ISPCM ) conference 2018 Busan, Korea 3/2018. 2018.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Wang Y., Leung T.H.Y., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis, BMC Cancer. 2017.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Leung T.H.Y. and Ngan H.Y.S., Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer., Cancer Cell Int.. 2018, 18.
Chan K.K.L., Robotic Surgery In Gynaecological Cancer, Hong Kong College of Obstetrics and Gynaecology 30th anniversary symposium. 2018.
Lam W.L., Yeung W.F., Wong M.K., Cheung C.W., Chan K.K.L., Ngan H.Y.S., Wong C.K.H., Chen H. and Lao L., Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial, Trials. 2018, 19: 8.
Leung T.H.Y., Tang W.M., Siu K.Y., Chan D.W., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., HPV-E6 protein enriches the CD55(+) population in cervical cancer cells promoting radio-resistance and cancer aggressiveness, The Journal of Pathology. 2017.
Ngan H.Y.S., Chan K.K.L., Tse K.Y., Chu M.Y.M., Ngu S.F. and Hui S., QMH/TYH Outstanding Teams (Walk Together with One Heart), HKWC cum QMH/TYH Outstanding Staff & Teams Award and Young Achiever Award for 2018. 2018.
Ngu S.F. and Chan K.K.L., Abdominal Hysterectomy: Instrumentation and Apparatuses, In: Ibrahim Alkatout, Liselotte Mettler, Hysterectomy A Comprehensive Surgical Approach. Springer, Cham, 2018, 1049-1057.
Ngu S.F. and Chan K.K.L., Abdominal Hysterectomy: Preparation, In: Ibrahim Alkatout, Liselotte Mettler, Hysterectomy A Comprehensive Surgical Approach. Springer, Cham, 2018, 1041-1047.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Bevacizumab in Epithelial Ovarian, Fallopian Tube and Primary Peritoneal Cancer: A Single Centre Experience, 20th International Meeting of The European Society of Gynaecological Oncology (ESGO 2017). 2017.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Recurrent Gestational Trophoblastic Neoplasia with Pulmonary Metastatic Choriocarcinoma: A Case Report, XIX World Congress on Gestational Trophoblastic Diseases, Amsterdam, Netherlands . 2017.
Ngu S.F., Chu M.Y.M., Tse K.Y., Chan K.K.L., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Role Of Lymphadenectomy And Vincristine, Actinomycin-D, and Cyclophosphamide Chemotherapy in Malignant Ovarian Germ Cell Tumors, European Journal of Gynaecological Oncology. 2018, 39(1): 63-69.
Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018.
Tse K.Y., Wei N., Kwan T.T.C., Chu M.Y.M., Ngu S.F., Chan K.K.L. and Ngan H.Y.S., Quality-of-life of ovarian cancer patients with prolonged use of chemotherapy - a prospective comparative quantitative and qualitative study, Poster presentation: 20thInternational Meeting of the European Society of Gynaecological Oncology; Vienna, Austria; 4 – 7 Nov 2017.
Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285.


Researcher : Chan KW
List of Research Outputs

Yung S.F.S., Chan K.W., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps, 33rd Annual Meeting of the European Society of Human Reproduction and Embryology (Human Reproduction). Oxford University Press, 2017, 32, Issue suppl_1: i331-2.


Researcher : Chan MKD
Project Title:A randomized double-blind controlled trial of use of progesterone in women with threatened miscarriage in the first trimester
Investigator(s):Chan MKD, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:12/2015




Researcher : Chan RWS
List of Research Outputs

CHENG H.C., Chan R.W.S., CAO M., Ng E.H.Y. and Yeung W.S.B., An investigation of matrix metalloproteinase 3 derived from myometrial cells on endometrial mesenchymal stem-like cells maintenance, 50th Society For The Study Of Reproduction. 2017, 63.


Researcher : Chan YK
Project Title:Validating and examining SNPs identified from genome-wide scanning for disease susceptibility to HBV-related liver cancer in Chinese population
Investigator(s):Chan YK, Ng IOL, Wong CM
Department:Pathology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2010


List of Research Outputs

Lo T.K., Chan Y.K., Kan S.Y.A., So P.L., Kong C.W., Mak S.L. and Lee C.N., Decision outcomes in women offered noninvasive prenatal test (NIPT) for positive Down screening results, The Journal of Maternal-Fetal & Neonatal Medicine. 2017, 1-3.
Lo T.K., Chan Y.K., Kan S.Y.A., So P.L., Kong C.W., Mak S.L. and Lee C.N., Effect of knowledge on women’s likely uptake of and willingness to pay for non-invasive test (NIPT), European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018, 222: 183-184.
Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8.


Researcher : Chan YLD
List of Research Outputs

Chan Y.L.D., Lam K.W., Lau Y.L.E., Yeung W.S.B. and Ng E.H.Y., Human varicella zoster virus is not present in the semen of a man affected by chickenpox during the in vitro fertilisation of his wife, Andrologia. 2017, 49: e12822.


Researcher : Chen CH
Project Title:Society for the Study of Reproduction 2017 Annual Meeting; Hyperglycemia impaired early pancreatic differentiation of human embryonic stem cells through aberration of DNA methylation patterns
Investigator(s):Chen CH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2017
Completion Date:07/2017


List of Research Outputs

Chen C.H., Lee C.Y.L., Fong S.W. and Yeung W.S.B., Hyperglycemia impaired early pancreatic differentiation of human embryonic stem cells through aberration of DNA methylation patterns, Society for the Study of Reproduction Annual Meeting 2017.


Researcher : Cheng HYH
List of Research Outputs

Cheng H.Y.H., Kan S.Y.A., Hui P.W., Lee C.P. and Tang M.H.Y., Bridging the gap from prenatal karyotyping to whole-genome array comparative genomic hybridization in Hong Kong: survey on knowledge and acceptance of health-care providers and pregnant women, Archives of Gynecology and Obstetrics. 2017, 296: 1109-1116.
Cheng H.Y.H. and Cheung V.Y.T., Patients on Long-Term Warfarin Undergo Gynecological Surgeries: A 10-Year Review of Peri-Operative Anticoagulation, Journal of Obstetrics and Gynaecology Canada. 2017.
Cheng H.Y.H. and Kan S.Y.A., Updates on Screening for Carriers of Genetic Diseases, Journal Of Paediatrics, obstetrics & Gynaecology. 2018, 44.


Researcher : Cheung KW
Project Title:A multi-center prospective study on the evaluation of paternal, maternal and obstetric factors leading to the hepatitis B immunization failure in Hong Kong
Investigator(s):Cheung KW, Seto TYM, Kan SYA, Ng EHY, Lau WL, Wong RMS, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:01/2014


List of Research Outputs

Cheung K.W., Lai W.S.C., MAK C.C.Y., Hui P.W., Chung B.H.Y. and Kan S.Y.A., A case of prenatal isolated talipes and 22q11.2 deletion syndrome-an important chromosomal disorder missed by noninvasive prenatal screening, Prenatal Diagnosis. 2018, 38(5): 376-378.
Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145.
Cheung K.W., Seto T.Y.M. and Ng E.H.Y., Tenofovir to Prevent Perinatal Transmission of Hepatitis B, New England Journal of Medicine. 2018, 378: 2348-2350.
Seto T.Y.M., Cheung K.W., TK L.O. and Ng E.H.Y., Pregnancy outcomes of women randomized to receive real versus placebo acupuncture on the day of fresh or frozen-thawed embryo transfer, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2017, 218: 119-122.


Researcher : Cheung SYC
List of Research Outputs

Cheung S.Y.C., Common vulvar and vaginal lesions in children and adolescents, Hospital Authority Obstetrics and Gynaecology Commissioned Training 2017/18. 17 January 2018. 2018.
Cheung S.Y.C., Genital tract injuries in children and adolescents, HKCOG Postgraduate Seminar Day on 12 November 2017. 2017.
Cheung V.Y.T. and Cheung S.Y.C., Thanks to the Young Gynaecologist Award Fellowship Program, Journal of Obstetrics and Gynaecology Research. 2018, 44: 808-808.


Researcher : Cheung VYT
List of Research Outputs

Cheng H.Y.H. and Cheung V.Y.T., Patients on Long-Term Warfarin Undergo Gynecological Surgeries: A 10-Year Review of Peri-Operative Anticoagulation, Journal of Obstetrics and Gynaecology Canada. 2017.
Cheung V.Y.T., Endometrial Cystic Atrophy, Journal of Minimally Invasive Gynecology. 2017, 24: 711.
Cheung V.Y.T., High-intensity focused ultrasound therapy, Best Practice & Research Clinical Obstetrics & Gynaecology. 2018, 46: 74-83.
Cheung V.Y.T., Re: Changes in anti-müllerian hormone levels as a biomarker for ovarian reserve after ultrasound-guided high-intensity focused ultrasound treatment of adenomyosis and uterine fibroid, BJOG: An International Journal of Obstetrics & Gynaecology. 2018, 125: 508-508.
Cheung V.Y.T. and Cheung S.Y.C., Thanks to the Young Gynaecologist Award Fellowship Program, Journal of Obstetrics and Gynaecology Research. 2018, 44: 808-808.
Ko K.Y.J. and Cheung V.Y.T., Comment on: Delayed intestinal perforation and vertebral osteomyelitis after high-intensity focused ultrasound treatment for uterine leiomyoma, Obstetrics & Gynecology Science. 2018, 61: 177.
Ko K.Y.J. and Cheung V.Y.T., Management of acquired uterine arteriovenous malformations following early pregnancy complications, Journal of Pediatrics, Obstetrics and Gynaecology. 2017, 169.
Lui M.W.E. and Cheung V.Y.T., Three-dimensional versus two-dimensional laparoscopy for ovarian cystectomy: a prospective randomised study, Hong Kong Medical Journal. 2018.


Researcher : Chiu CN
Project Title:The roles of protein disulfide isomerase family A, member 3 (ERp57) and surface thiol/disulfide exchange in spermatozoa-zona pellucida binding and their association with fertilization in vitro.
Investigator(s):Chiu CN, Pang TKR, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2012


Project Title:The role of galectin-3 in spermatozoa-zona pellucida binding and its association with fertilization in vitro
Investigator(s):Chiu CN, Yeung WSB, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Control of human extravillous cytotrophoblast functions by adrenomedullin and its association with preeclampsia
Investigator(s):Chiu CN, Yeung WSB, Kan SYA
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2015


Project Title:The role of glycodelin-A on the vascular remodeling function of decidual natural killer cells during early pregnancy and its association with preeclampsia
Investigator(s):Chiu CN, Wong AST, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:10/2015


Project Title:The roles of spermatozoa-oviductal epithelial cell interaction on the selection of fertilization-competent sperm and fertilization in humans
Investigator(s):Chiu CN, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2018


List of Research Outputs

Chinoy Z.S., Friscourt F., Capicciotti C.J., Chiu C.N. and Boons G.J., Chemoenzymatic Synthesis of Asymmetrical Multi-Antennary N-Glycans to Dissect Glycan-Mediated Interactions between Human Sperm and Oocytes , Chemistry - A European Journal. 2018, 24: 7970-7975.
Chiu C.N., Glycodelin: A major decidual protein plays an important role in regulating immune cells during early pregnancy. , 全军第七次生殖医学年 会暨生殖免疫新进展研 讨会. 2017 Sept 1-3, Chongqing, China, 2017.
Lee C.L., Yeung W.S.B. and Chiu C.N., Glycodelin-A interacts with L-selectin on CD16-CD56bright natural killer cells to induce endothelial cell angiogenesis and trophoblast invasion, 33rd Annual Meeting of European Society of Human Reproduction and Embryology. 2017.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The regulatory roles of decidual glycodelin-A on trophoblast and immune cell functions during early pregnancy., The 38th Annual Meeting of the American Society for Reproductive Immunology. 2018 Jun 28-July 1, Shanghai, China.. 2018.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The roles of decidual glycodelin-A in placental development and fetomaternal tolerance during early pregnancy., 1st Asia Pacific Reproductive Immunology Forum. 2017 Dec 9, Seoul, Korea.. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., Global Health Travel Awards: Decidual glycodelin-A drives human monocyte to macrophage differentiation and functions via siglec-7., Maternal‐Fetal Crosstalk: Harmony vs. Conflict. 2017 Oct 4-8, Westin Washington, DC City Center, Washington, DC, USA.. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., The Role of Decidual Glycodelin-A in regulating Macrophage Functions. , Immunological Aspects in Andrology. 2017 Sept 9, Shenzhen, China.. 2017.
WANG X., Lee C.L., Li R.H.W. and Chiu C.N., Best Oral Presentation Award: Adrenomedullin regulates macrophage functions in inflammation-induced tubal ectopic pregnancy, The Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction. 2017 Nov 12 Hong Kong.. 2017.


Researcher : Chow JFC
List of Research Outputs

Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau Y.L.E. and Ng E.H.Y., Evaluation of preimplantation genetic testing for chromosomal structural rearrangement by a commonly used next generation sequencing workflow, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018, 224: 66-73.
Lee V.C.Y., Chow J.F.C., Yeung W.S.B. and Ho P.C., Preimplantation genetic diagnosis for monogenic diseases, Best Practice & Research Clinical Obstetrics & Gynaecology. 2017, 44: 68-75.


Researcher : Chu KH
List of Research Outputs

Szeto Y.Y., Chu K.H., Au Y.K., Huang Y.-.H., Wynn S., Mak A...C...Y..., Chan W...Y..., Jauch R., Fritzsch B., Lovell-Badge R., Sham M.H. and Cheah K.S.E., Cooperation between SOX9 and SOX10 is required for hearing via regulation of genes involved in inner ear fluid homeostasis, Molecular Biology of Hearing and Deafness 2018.


Researcher : Chu MYM
List of Research Outputs

Ngan H.Y.S., Chan K.K.L., Tse K.Y., Chu M.Y.M., Ngu S.F. and Hui S., QMH/TYH Outstanding Teams (Walk Together with One Heart), HKWC cum QMH/TYH Outstanding Staff & Teams Award and Young Achiever Award for 2018. 2018.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Bevacizumab in Epithelial Ovarian, Fallopian Tube and Primary Peritoneal Cancer: A Single Centre Experience, 20th International Meeting of The European Society of Gynaecological Oncology (ESGO 2017). 2017.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Recurrent Gestational Trophoblastic Neoplasia with Pulmonary Metastatic Choriocarcinoma: A Case Report, XIX World Congress on Gestational Trophoblastic Diseases, Amsterdam, Netherlands . 2017.
Ngu S.F., Chu M.Y.M., Tse K.Y., Chan K.K.L., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Role Of Lymphadenectomy And Vincristine, Actinomycin-D, and Cyclophosphamide Chemotherapy in Malignant Ovarian Germ Cell Tumors, European Journal of Gynaecological Oncology. 2018, 39(1): 63-69.
Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018.
Tse K.Y., Wei N., Kwan T.T.C., Chu M.Y.M., Ngu S.F., Chan K.K.L. and Ngan H.Y.S., Quality-of-life of ovarian cancer patients with prolonged use of chemotherapy - a prospective comparative quantitative and qualitative study, Poster presentation: 20thInternational Meeting of the European Society of Gynaecological Oncology; Vienna, Austria; 4 – 7 Nov 2017.


Researcher : Fan H
List of Research Outputs

Fan H. and Lee C.K.F., Bisphenol Compounds on Human Reproduction Health, Gynecology and Obstetrics Research – Open Journal. 2017, 4: 30-35.


Researcher : Fong SW
List of Research Outputs

Chen C.H., Lee C.Y.L., Fong S.W. and Yeung W.S.B., Hyperglycemia impaired early pancreatic differentiation of human embryonic stem cells through aberration of DNA methylation patterns, Society for the Study of Reproduction Annual Meeting 2017.


Researcher : Gemzell Danielsson EKM
List of Research Outputs

Cameron S.T., Li R.H.W. and Gemzell Danielsson E.K.M., Current controversies with oral emergency contraception, BJOG: An International Journal of Obstetrics & Gynaecology. 2017.


Researcher : Ho PC
List of Research Outputs

Ho P.C., Development of medical termination of pregnancy: a review, BJOG: An International Journal of Obstetrics & Gynaecology. 2017, 124: 1942-1947.
Lee V.C.Y., Chow J.F.C., Yeung W.S.B. and Ho P.C., Preimplantation genetic diagnosis for monogenic diseases, Best Practice & Research Clinical Obstetrics & Gynaecology. 2017, 44: 68-75.
Li R.H.W., Li Y.X., Li T.T., Fan H.J., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Effect of ulipristal acetate and mifepristone at emergency contraception dose on the embryo-endometrial attachment using an in vitro human trophoblastic spheroid and endometrial cell co-culture model, Human Reproduction. 2017, 32: 2414-2422.
Li R.H.W., Lam K.S.L., Tam S., Wong E., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction Of Metabolically Unhealthy Phenotype By The Visceral Accumulation Index, Lipid Accumulation Index And Triglyceride-glucose Index In Chinese Women With Polycystic Ovary Syndrome, European Society of Human Reproduction and Embryology Annual Meeting, 2-5 Jul 2017, Geneva, Switzerland. 2017.
Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of incident metabolic syndrome and dysglycaemia by adiposity and insulin resistance indices in Chinese women with polycystic ovary syndrome: a 4-year longitudinal study, 100th Annual Meeting & Expo of the Endocrine Society. 2018.
Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of metabolically unhealthy phenotype by the visceral adiposity index, lipid accumulation product and triglyceride-glucose index in Chinese women with polycystic ovary syndrome, 33rd Annual Meeting, European Society of Human Reproduction and Embryology. 2017.
Morris J.L., Winkikoff B., Dabash R., Weeks A., Faundes A., Gemzell-Danielsson K., Kapp N., Castleman L., Kim C., Ho P.C. and Visser G.H.A., FIGO's updated recommendations for misoprostol used alone in gynecology and obstetrics, International Journal of Gynecology & Obstetrics. 2017, 138: 363-366.


Researcher : Hui MN
List of Research Outputs

Liu A.J., RAO Y., Cheung M.P.L., Hui M.N., Wu M.H., Chan L.K., Ng I.O.L., Niu B., Cheah K.S.E., Sharma R., Hodgson L. and Cheung M.C.H., Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration, In: J Ann Le Good, Nature Communications. 2017, 8: 1185.
Liu A.J., Hui M.N., Wu M.H. and Cheung M.C.H., Elucidating the roles of SOX9 in human neural stem cells., Keystone Symposium: Regenerative Biology and Applications: Cell Differentiation, Tissue Organization and Biomedical Engineering (T3). 2017.
Liu A.J., Rao Y.X., Cheung M.P.L., Hui M.N., Wu M.H., Chan L.K., Ng I.O.L., Niu B., Cheah K.S.E. and Hodgson L., Faculty Outstanding Research Output Award , Li Ka Shing Faculty of Medicine, The University of Hong Kong. 2017, 1185: 1185.
Liu J., Rao Y., Cheung M., Hui M.N., Wu M.H., Chan L.K., Ng I.O.L., Niu B., Cheak K., Sharma R., Hodgson L. and Cheung M., Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration, Nat Commun . 2017.


Researcher : Hui PW
Project Title:31st British International Congress of Obstetrics & Gynaecology 2007 A rare cause of Thrombocytopenia in Pregnancy-EDTA-dependent Pseudothrombocytopenia
Investigator(s):Hui PW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2007


List of Research Outputs

Cheng H.Y.H., Kan S.Y.A., Hui P.W., Lee C.P. and Tang M.H.Y., Bridging the gap from prenatal karyotyping to whole-genome array comparative genomic hybridization in Hong Kong: survey on knowledge and acceptance of health-care providers and pregnant women, Archives of Gynecology and Obstetrics. 2017, 296: 1109-1116.
Cheung K.W., Lai W.S.C., MAK C.C.Y., Hui P.W., Chung B.H.Y. and Kan S.Y.A., A case of prenatal isolated talipes and 22q11.2 deletion syndrome-an important chromosomal disorder missed by noninvasive prenatal screening, Prenatal Diagnosis. 2018, 38(5): 376-378.


Researcher : JIANG Y
List of Research Outputs

Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Wang Y., Leung T.H.Y., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis, BMC Cancer. 2017.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Leung T.H.Y. and Ngan H.Y.S., Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer., Cancer Cell Int.. 2018, 18.


Researcher : Kan SYA
List of Research Outputs

Cheng H.Y.H., Kan S.Y.A., Hui P.W., Lee C.P. and Tang M.H.Y., Bridging the gap from prenatal karyotyping to whole-genome array comparative genomic hybridization in Hong Kong: survey on knowledge and acceptance of health-care providers and pregnant women, Archives of Gynecology and Obstetrics. 2017, 296: 1109-1116.
Cheng H.Y.H. and Kan S.Y.A., Updates on Screening for Carriers of Genetic Diseases, Journal Of Paediatrics, obstetrics & Gynaecology. 2018, 44.
Cheung K.W., Lai W.S.C., MAK C.C.Y., Hui P.W., Chung B.H.Y. and Kan S.Y.A., A case of prenatal isolated talipes and 22q11.2 deletion syndrome-an important chromosomal disorder missed by noninvasive prenatal screening, Prenatal Diagnosis. 2018, 38(5): 376-378.
Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145.
Kan S.Y.A., Lau E.T.K., So C.H., Chan W.P., Wong W.C., Lee K.C., Pertile M.D. and Tang M.H.Y., A fetus coexisting with a complete hydatidiform mole with trisomy 9 of maternal origin, Journal of Obstetrics and Gynaecology Research. 2018, 44: 955-959.
LEUNG K.C., Kan S.Y.A. and Chung B.H.Y., Next Generation Sequencing in Prenatal Diagnosis, 12th Asia-Pacific Conference on Human Genetics "Genomic Medicine and Clinical Practice", Bangkok, Thailand, 8-10 November 2017.
LEUNG K.C., Kan S.Y.A. and Chung B.H.Y., Next generation sequencing in prenatal diagnosis, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017.
Lo T.K., Chan Y.K., Kan S.Y.A., So P.L., Kong C.W., Mak S.L. and Lee C.N., Decision outcomes in women offered noninvasive prenatal test (NIPT) for positive Down screening results, The Journal of Maternal-Fetal & Neonatal Medicine. 2017, 1-3.
Lo T.K., Chan Y.K., Kan S.Y.A., So P.L., Kong C.W., Mak S.L. and Lee C.N., Effect of knowledge on women’s likely uptake of and willingness to pay for non-invasive test (NIPT), European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018, 222: 183-184.
Poon W.Y.S., Tao Q.V., Kan S.Y.A. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis, Hong Kong Journal of Paediatrics (new series). 2018, 23(1): 141.
So P.L., Cheng Y.K.Y., Cheuk K.Y., Chiu W.K., Mak S.L., Mok S.L., Lo T.K., Yung W.K., Lo F.M., Chung B.H.Y., Kan S.Y.A., Lee C.P. and Tang M.H.Y., Parental decisions following prenatal diagnosis of sex chromosome aneuploidy in Hong Kong, The Journal of Obstetrics and Gynaecology Research. 2017, 43(12): 1821-1829.


Researcher : Ko KYJ
List of Research Outputs

Ko K.Y.J. and Cheung V.Y.T., Comment on: Delayed intestinal perforation and vertebral osteomyelitis after high-intensity focused ultrasound treatment for uterine leiomyoma, Obstetrics & Gynecology Science. 2018, 61: 177.
Ko K.Y.J. and Cheung V.Y.T., Management of acquired uterine arteriovenous malformations following early pregnancy complications, Journal of Pediatrics, Obstetrics and Gynaecology. 2017, 169.
Wong Q.H.Y., Yeung T.W.Y., Yung S.F.S., Ko K.Y.J., Li R.H.W. and Ng E.H.Y., The effect of 12-month dehydroepiandrosterone supplementation on the menstrual pattern, ovarian reserve markers, and safety profile in women with premature ovarian insufficiency, Journal of Assisted Reproduction and Genetics. 2018, 35: 857-862.


Researcher : LEUNG LL
List of Research Outputs

LEUNG L.L., Yung M.H., Ngan H.Y.S. and Chan D.W., The secretary miR-141 facilitates ovarian cancer metastasis through reprogramming stromal fibroblast cells in pre-metastatic niches formation, the 25th Biennial Congress of the European Association for Cancer Research (EACR25). 2018.
LEUNG L.L., Lam S.K., Li Y.V. and Ho J.C.M., Tumour Growth Suppressive Effect of Arsenic Trioxide in Squamous Cell Lung Carcinoma, Oncology letters. 2017, 14: 3748-3754.


Researcher : Lai WSC
List of Research Outputs

Cheung K.W., Lai W.S.C., MAK C.C.Y., Hui P.W., Chung B.H.Y. and Kan S.Y.A., A case of prenatal isolated talipes and 22q11.2 deletion syndrome-an important chromosomal disorder missed by noninvasive prenatal screening, Prenatal Diagnosis. 2018, 38(5): 376-378.


Researcher : Lam KW
List of Research Outputs

Chan Y.L.D., Lam K.W., Lau Y.L.E., Yeung W.S.B. and Ng E.H.Y., Human varicella zoster virus is not present in the semen of a man affected by chickenpox during the in vitro fertilisation of his wife, Andrologia. 2017, 49: e12822.


Researcher : Lam YH
Project Title:11th World Congress on Ultrasound in Obstetrics and Gynecology Integrated First and Second Trimester Screening for Down Syndrome
Investigator(s):Lam YH
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2001




Researcher : Lao TTH
Project Title:The First Congress on Obstetrics, Gynecology & Infertility Does Impaired Glucose Tolerance Impact on Pregnancy Outcome?
Investigator(s):Lao THT
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/1999


Project Title:Dietary caloric intake and the development of gestational diabetes mellitus in at-risk Chinese women
Investigator(s):Lao THT, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2002


Project Title:Elevated TNF-α in gestational diabetes mellitus-cause or consequence?
Investigator(s):Lao THT, Leung WC, Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The relationship between the antioxidant defense system with the development of gestational diabetes mellitus and its complications in the Chinese population.
Investigator(s):Lao THT
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:12/2005




Researcher : Lau ETK
List of Research Outputs

Kan S.Y.A., Lau E.T.K., So C.H., Chan W.P., Wong W.C., Lee K.C., Pertile M.D. and Tang M.H.Y., A fetus coexisting with a complete hydatidiform mole with trisomy 9 of maternal origin, Journal of Obstetrics and Gynaecology Research. 2018, 44: 955-959.
Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8.


Researcher : Lau YLE
List of Research Outputs

Chan Y.L.D., Lam K.W., Lau Y.L.E., Yeung W.S.B. and Ng E.H.Y., Human varicella zoster virus is not present in the semen of a man affected by chickenpox during the in vitro fertilisation of his wife, Andrologia. 2017, 49: e12822.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau Y.L.E. and Ng E.H.Y., Evaluation of preimplantation genetic testing for chromosomal structural rearrangement by a commonly used next generation sequencing workflow, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018, 224: 66-73.


Researcher : Lee CKF
Project Title:Functional characterization of VAD1.3, a novel acrosome-specific protein by conditional tissue-specific gene inactivation
Investigator(s):Lee CKF, Cheah KSE, Yeung WSB, Luk JMC, Lee NPY
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2006


Project Title:Environmental Screening, Computational and Biological Characterization of Endocrine Disruptors, in Respect to Receptor Binding, Embryo and Gonad Physiology
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Collaborative Research Fund (CRF) - Group Research Project
Start Date:06/2009


Project Title:Human embryonic stem cell-derived trophoblastic cells for the development of a novel implantation model
Investigator(s):Lee CKF, Ng EHY, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015


Project Title:Bisphenol A analogues: Mechanistic actions on Embryo implantation and Endometrial Receptivity
Investigator(s):Lee CKF, Ng EHY, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:Mechanistic study of endocrine disrupting chemical Mancozeb (Manganese ethylene bisdithiocarbamate) on implantation
Investigator(s):Lee CKF
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


Project Title:The use of endometrial surface proteins for human endometrial receptivity prediction
Investigator(s):Lee CKF, Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:05/2018


List of Research Outputs

Ahmad S.F., Brown J.K., Campbell L.L., Koscielniak M., Oliver C., Wheelhouse N., Entrican G., McFee S., Wills G.S., McClure M.O., Horner P.J., Gaikoumelou S., Lee C.K.F., Critchley H.O.D., Duncan W.C. and Horne A.W., Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin β1 to Promote Embryo-tubal Attachment., EBioMedicine. 2018, 29: 159-165.
Fan H. and Lee C.K.F., Bisphenol Compounds on Human Reproduction Health, Gynecology and Obstetrics Research – Open Journal. 2017, 4: 30-35.
Lee C.K.F., Choriocarcinoma spheroid model for Eutopic and Ectopic pregnancy- Workshop on in vitro implantation models, Hong Kong University-ShenZhen Hospital and College of Veterinary Medicine, South China Agricultural University.. 2017.
Lee C.K.F., Choriocarcinoma spheroid model for Eutopic and Ectopic pregnancy, Workshop on in vitro implantation models’-Hong Kong University-ShenZhen Hospital and College of Veterinary Medicine, South China Agricultural University. 2017.
Lee C.K.F., Endocrine disruptors on embryo implantation and offspring fertility in mice., MME. Soong Ching Ling Forum-Medical symposium 2017 and 65th Anniversary academic celebration. 2017.
Lee C.K.F., Endocrine disruptors on embryo implantation and offspring fertility in mice, MME. Soong Ching Ling Forum-Medical symposium 2017 and 65th Anniversary academic celebration. 15-17 Sep 2017, Shanghai, China. 2017.
Li R.H.W., Li Y.X., Li T.T., Fan H.J., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Effect of ulipristal acetate and mifepristone at emergency contraception dose on the embryo-endometrial attachment using an in vitro human trophoblastic spheroid and endometrial cell co-culture model, Human Reproduction. 2017, 32: 2414-2422.
Thach T.Q., Tsang H., Lai P.C., Lee C.K.F. and Barratt B.M., Effects of maternal exposure to particulate matter on birth weight by Parental Educational Attainment in Hong Kong, One Health International Conference 2017, Bangkok, Thailand, 14-15 December 2017.. 2017.
Thach T.Q., Tsang H., Lai P.C., Lee C.K.F. and Barratt B.M., Effects of maternal exposure to particulate matter on birth weight in Hong Kong, International Society of Environmental Epidemiology Conference, Sydney, Australia, 24-28 September 2017. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., Global Health Travel Awards: Decidual glycodelin-A drives human monocyte to macrophage differentiation and functions via siglec-7., Maternal‐Fetal Crosstalk: Harmony vs. Conflict. 2017 Oct 4-8, Westin Washington, DC City Center, Washington, DC, USA.. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., The Role of Decidual Glycodelin-A in regulating Macrophage Functions. , Immunological Aspects in Andrology. 2017 Sept 9, Shenzhen, China.. 2017.
WANG Z., Kottawatta K...S...A..., Kodithuwakku S...P... and Lee C.K.F., Effect of Fungicide Mancozeb and its metabolite Ethylenethiourea (ETU) on spheroid attachment and transcriptomic changes in Ishikawa cells, Oral presentation. O3. The Hong Kong Society of Endocrinology, Metabolism and Reproduction 34rd Annual Scientific Meeting, 12 Nov 2017, Hong Kong. 2017.
WANG Z., Kottawatta K...S...A..., Kodithuwakku S...P... and Lee C.K.F., Exposure to Mancozeb impairs embryo implantation via disrupting embryo- epithelium interaction in vitro trophoblast/endometrial cells co-culture model, P-442. European Society of Human reproduction and embryology, 33rd Annual Meeting.2-5 July 2017, Geneva, Switzerland. 2017.
WANG Z., Kottawatta K...S...A..., Kodithuwakku S...P... and Lee C.K.F., The effect of Mancozeb on spheroid attachment in vitro co-culture model and gene expression profiling of Ishikawa cells, P5.09. The University of Hong Kong, Li Ka Shing Faculty of Medicine 22nd Research Postgraduate Symposium.6-7 Dec 2017, Hong Kong, China. 2017.
Wang X., Wang G.C., Rong J., Wang S., Ng T.B., Zhang Y., Lee C.K.F., Zheng L., Wong H.K. and Sze C.W.S., Identification of Steroidogenic Components Derived From Gardenia jasminoides Ellis Potentially Useful for Treating Postmenopausal Syndrome, Frontiers in Pharmacology. 2018, 9.
Wong Y.M., Li R., Lee C.K.F., Wan H.T. and Wong C.K.C., The measurement of bisphenol A and its analogues, perfluorinated compounds in twenty species of freshwater and marine fishes, a time-trend comparison and human health based assessment, Marine Pollution Bulletin. 2017, 124: 743-752.
Yung S.F.S., Chan K.W., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps, 33rd Annual Meeting of the European Society of Human Reproduction and Embryology (Human Reproduction). Oxford University Press, 2017, 32, Issue suppl_1: i331-2.


Researcher : Lee CL
Project Title:Doris Zimmern HKU-Cambridge Hughes Hall Fellowships 2017-18
Investigator(s):Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Doris Zimmern HKU-Cambridge Hughes Hall Fellowships
Start Date:09/2017


List of Research Outputs

Lee C.L., Yeung W.S.B. and Chiu C.N., Glycodelin-A interacts with L-selectin on CD16-CD56bright natural killer cells to induce endothelial cell angiogenesis and trophoblast invasion, 33rd Annual Meeting of European Society of Human Reproduction and Embryology. 2017.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The regulatory roles of decidual glycodelin-A on trophoblast and immune cell functions during early pregnancy., The 38th Annual Meeting of the American Society for Reproductive Immunology. 2018 Jun 28-July 1, Shanghai, China.. 2018.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The roles of decidual glycodelin-A in placental development and fetomaternal tolerance during early pregnancy., 1st Asia Pacific Reproductive Immunology Forum. 2017 Dec 9, Seoul, Korea.. 2017.
Lee C.L., University of Hong Kong-China Medical Board Grants, The University of Hong Kong. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., Global Health Travel Awards: Decidual glycodelin-A drives human monocyte to macrophage differentiation and functions via siglec-7., Maternal‐Fetal Crosstalk: Harmony vs. Conflict. 2017 Oct 4-8, Westin Washington, DC City Center, Washington, DC, USA.. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., The Role of Decidual Glycodelin-A in regulating Macrophage Functions. , Immunological Aspects in Andrology. 2017 Sept 9, Shenzhen, China.. 2017.
WANG X., Lee C.L., Li R.H.W. and Chiu C.N., Best Oral Presentation Award: Adrenomedullin regulates macrophage functions in inflammation-induced tubal ectopic pregnancy, The Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction. 2017 Nov 12 Hong Kong.. 2017.


Researcher : Lee CP
List of Research Outputs

Cheng H.Y.H., Kan S.Y.A., Hui P.W., Lee C.P. and Tang M.H.Y., Bridging the gap from prenatal karyotyping to whole-genome array comparative genomic hybridization in Hong Kong: survey on knowledge and acceptance of health-care providers and pregnant women, Archives of Gynecology and Obstetrics. 2017, 296: 1109-1116.
Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145.
So P.L., Cheng Y.K.Y., Cheuk K.Y., Chiu W.K., Mak S.L., Mok S.L., Lo T.K., Yung W.K., Lo F.M., Chung B.H.Y., Kan S.Y.A., Lee C.P. and Tang M.H.Y., Parental decisions following prenatal diagnosis of sex chromosome aneuploidy in Hong Kong, The Journal of Obstetrics and Gynaecology Research. 2017, 43(12): 1821-1829.


Researcher : Lee CYL
Project Title:Prediction of the live birth rate of in vitro fertilization using a novel human embryonic stem cells derived trophoblastic spheroid implantation model
Investigator(s):Lee CYL, Ng EHY, Yeung WSB, Lee CKF, Li RHW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health and Medical Research Fund - Full Grant
Start Date:08/2017


List of Research Outputs

Chen C.H., Lee C.Y.L., Fong S.W. and Yeung W.S.B., Hyperglycemia impaired early pancreatic differentiation of human embryonic stem cells through aberration of DNA methylation patterns, Society for the Study of Reproduction Annual Meeting 2017.


Researcher : Lee VCY
List of Research Outputs

Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau Y.L.E. and Ng E.H.Y., Evaluation of preimplantation genetic testing for chromosomal structural rearrangement by a commonly used next generation sequencing workflow, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018, 224: 66-73.
Lee V.C.Y., Chow J.F.C., Yeung W.S.B. and Ho P.C., Preimplantation genetic diagnosis for monogenic diseases, Best Practice & Research Clinical Obstetrics & Gynaecology. 2017, 44: 68-75.
Li R.H.W., Lam K.S.L., Tam S., Wong E., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction Of Metabolically Unhealthy Phenotype By The Visceral Accumulation Index, Lipid Accumulation Index And Triglyceride-glucose Index In Chinese Women With Polycystic Ovary Syndrome, European Society of Human Reproduction and Embryology Annual Meeting, 2-5 Jul 2017, Geneva, Switzerland. 2017.
Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of incident metabolic syndrome and dysglycaemia by adiposity and insulin resistance indices in Chinese women with polycystic ovary syndrome: a 4-year longitudinal study, 100th Annual Meeting & Expo of the Endocrine Society. 2018.
Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of metabolically unhealthy phenotype by the visceral adiposity index, lipid accumulation product and triglyceride-glucose index in Chinese women with polycystic ovary syndrome, 33rd Annual Meeting, European Society of Human Reproduction and Embryology. 2017.


Researcher : Leung THY
List of Research Outputs

CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Wang Y., Leung T.H.Y., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis, BMC Cancer. 2017.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Leung T.H.Y. and Ngan H.Y.S., Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer., Cancer Cell Int.. 2018, 18.
Leung T.H.Y., Tang W.M., Siu K.Y., Chan D.W., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., HPV-E6 protein enriches the CD55(+) population in cervical cancer cells promoting radio-resistance and cancer aggressiveness, The Journal of Pathology. 2017.
Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285.


Researcher : Li RHW
Project Title:Role of adrenomedullin and inflammatory mediators in pathogenesis of tubal ectopic pregnancy
Investigator(s):Li RHW, Cheung BMY, O WS, Lee CKF, Chiu CN
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2015
Completion Date:12/2017


Project Title:ENDO 2018 (and the satellite meeting "Androgen Excess and PCOS Update Meeting"); Prediction of Incident Metabolic Syndrome and Dysglycaemia by Adiposity and Insulin Resistance Indices in Chinese Women with Polycystic Ovary Syndrome: a 4-Year Longitudinal Study
Investigator(s):Li RHW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:03/2018
Completion Date:03/2018


List of Research Outputs

Cameron S.T., Li R.H.W. and Gemzell Danielsson E.K.M., Current controversies with oral emergency contraception, BJOG: An International Journal of Obstetrics & Gynaecology. 2017.
Iliodromiti S., Salje B., Dewailly D., Fairburn C., Fanchin R., Fleming R., Li R.H.W., Lukaszuk K., Ng E.H.Y., Pigny P., Tadros T., van Helden J., Weiskirchen R. and Nelson S.M., Non-equivalence of anti-Müllerian hormone automated assays—clinical implications for use as a companion diagnostic for individualised gonadotrophin dosing, Human Reproduction. 2017, 32: 1710-1715.
Li R.H.W., Clinical application of anti-Mullerian hormone measurement: an update., Royal Australian and New Zealand College of Obstetricians and Gynaecologists 2017 Annual Scientific Meeting. 2017.
Li R.H.W., Clinical application of anti-Mullerian hormone measurement: an update, Royal Australian and New Zealand College of Obstetricians and Gynaecologists 2017 Annual Scientific Meeting, Auckland, New Zealand. 2017.
Li R.H.W., Li Y.X., Li T.T., Fan H.J., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Effect of ulipristal acetate and mifepristone at emergency contraception dose on the embryo-endometrial attachment using an in vitro human trophoblastic spheroid and endometrial cell co-culture model, Human Reproduction. 2017, 32: 2414-2422.
Li R.H.W., Lo S.T.S., Wong C.Y.G., Kok W.M., Chan C.H.Y. and Ng E.H.Y., Effects of sexual dysfunction on fertility-related quality of life of oneself and the partner in infertile Chinese couples, 15th Congress of the European Society of Contraception and Reproductive Health. 2018.
Li R.H.W., Lam K.S.L., Tam S., Wong E., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction Of Metabolically Unhealthy Phenotype By The Visceral Accumulation Index, Lipid Accumulation Index And Triglyceride-glucose Index In Chinese Women With Polycystic Ovary Syndrome, European Society of Human Reproduction and Embryology Annual Meeting, 2-5 Jul 2017, Geneva, Switzerland. 2017.
Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of incident metabolic syndrome and dysglycaemia by adiposity and insulin resistance indices in Chinese women with polycystic ovary syndrome: a 4-year longitudinal study, 100th Annual Meeting & Expo of the Endocrine Society. 2018.
Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of metabolically unhealthy phenotype by the visceral adiposity index, lipid accumulation product and triglyceride-glucose index in Chinese women with polycystic ovary syndrome, 33rd Annual Meeting, European Society of Human Reproduction and Embryology. 2017.
Li R.H.W., Update on menopausal hormone therapy, 15th National Conference of the Nepal Society of Obstetricians and Gynaecologists. 2018.
WANG X., Lee C.L., Li R.H.W. and Chiu C.N., Best Oral Presentation Award: Adrenomedullin regulates macrophage functions in inflammation-induced tubal ectopic pregnancy, The Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction. 2017 Nov 12 Hong Kong.. 2017.
Wong Q.H.Y., Yeung T.W.Y., Yung S.F.S., Ko K.Y.J., Li R.H.W. and Ng E.H.Y., The effect of 12-month dehydroepiandrosterone supplementation on the menstrual pattern, ovarian reserve markers, and safety profile in women with premature ovarian insufficiency, Journal of Assisted Reproduction and Genetics. 2018, 35: 857-862.


Researcher : Li TKT
List of Research Outputs

Bian X., Biswas A., Huang X., Lee K.J., Li T.K.T., Masuyama H., Ohkuchi A., Park J.S., Saito S., Tan K.H., Yamamoto T., Dietl A., Grill S., Verhagen-Kamerbeek W.D.J., Hund M. and Shim J.-.Y., PROGNOSIS Asia: Prediction of Short-Term Outcome in Pregnant Women with Suspected Preeclampsia Study using the sFlt-1/PlGF ratio in An Asian Population, 2nd BCM-Chinese University of Hong Kong-Fudan Joint Symposium in Clinical Genetics and Birth Defects cum 14th Asia Pacific Congress in Maternal Fetal Medicine, Hong Kong, China, 18 - 21, May, 2018.
Li T.K.T., Caesarean section for deeply engaged foetal head, Journal of Pregnancy and Neonatal Medicine. 2018, 2: 3-4.
Li T.K.T., PROGNOSIS Asia: Prediction of Short-Term Outcome in Pregnant Women with Suspected Preeclampsia Study using the sFlt-1/PlGF ratio in An Asian Population, Royal College of Obstetricians and Gynaecologists World Congress 2018, Singapore, 21-24 March, 2018.
Li T.K.T., 妊娠毒血症 (子癇前症), 醫與研, Clinical Trials Centre, 2018, 110-113.


Researcher : Liao S
Project Title:Molecular regulation of meiotic resumption and chromosome segregation in mouse and human oocytes
Investigator(s):Liao S
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:06/2014




Researcher : Lim PC
List of Research Outputs

Ngan H.Y.S. and Lim P.C., Robotic surgery in gynecology, Best Pract Res Clin Obstet Gynaecol.. 2017.


Researcher : Liu S
List of Research Outputs

Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Wang Y., Leung T.H.Y., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis, BMC Cancer. 2017.
Meng Y., Chen C.W., Yung M.H., Sun W., Sun J., Li Z., Li J., Li Z., Zhou W., Liu S., Cheung A.N.Y., Ngan H.Y.S., Braisted J.C., Kai Y., Peng W., Tzatsos A., Li Y., Dai Z., Zheng W., Chan D.W. and Zhu W., DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer, Cancer Letters. 2018.
Zhou W., Sun W., Yung M.H., Dai S., Cai Y., Chen C.W., Meng Y., Lee J.B., Braisted J.C., Xu Y., Southall N.T., Shinn P., Huang X., Song Z., Chen X., Kai Y., Cai X., Li Z., Hao Q., Cheung A.N.Y., Ngan H.Y.S., Liu S., Barak S., Hao J., Dai Z., Tzatsos A., Peng W., Pei H., Han Z., Chan D.W., Zheng W. and Zhu W., Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance, Oncogene. 2018.


Researcher : Liu W
Project Title:Roles of microRNA lethal-7 on blastulation of mice embryos
Investigator(s):Liu W, Yeung WSB
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:03/2014


Project Title:SRF 2015 annual Conference; Mechanism of microRNA lethal-7 in embryo dormancy in mice
Investigator(s):Liu W
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:07/2015


Project Title:four world congress of reproductive biology; The involvement of endometrial exosome/microvesicle in the regulation of embryo dormancy in mice
Investigator(s):Liu W
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:09/2017




Researcher : Lo STS
List of Research Outputs

Li R.H.W., Lo S.T.S., Wong C.Y.G., Kok W.M., Chan C.H.Y. and Ng E.H.Y., Effects of sexual dysfunction on fertility-related quality of life of oneself and the partner in infertile Chinese couples, 15th Congress of the European Society of Contraception and Reproductive Health. 2018.


Researcher : Lo TK
List of Research Outputs

So P.L., Cheng Y.K.Y., Cheuk K.Y., Chiu W.K., Mak S.L., Mok S.L., Lo T.K., Yung W.K., Lo F.M., Chung B.H.Y., Kan S.Y.A., Lee C.P. and Tang M.H.Y., Parental decisions following prenatal diagnosis of sex chromosome aneuploidy in Hong Kong, The Journal of Obstetrics and Gynaecology Research. 2017, 43(12): 1821-1829.


Researcher : Lui MWE
List of Research Outputs

Lui M.W.E. and Cheung V.Y.T., Three-dimensional versus two-dimensional laparoscopy for ovarian cystectomy: a prospective randomised study, Hong Kong Medical Journal. 2018.


Researcher : MAK SL
List of Research Outputs

CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436.


Researcher : Ng EHY
Project Title:The 17th IFFS World Congress on Fertility and Sterility 1) Measurement of Serum CA-125 Concentrations Does not Improve the Value of Chlamydia Trachomatis Antibody (CAT) in Predicting Tubal Pathology at Laparoscopy 2) A Comparison of the Pain Levels During Egg Collection and Postoperative Side Effects Using Paracervical Block with and without Conscious Sedation
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2001


Project Title:Comparison of the prevalence of polycystic ovary only and polycystic ovary syndrome between two different ethnic populations
Investigator(s):Ng EHY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2005


Project Title:Myometrial cells modulate the activities of endometrial mesenchymal-like stem cells
Investigator(s):Ng EHY, Lee CKF, Yeung WSB, Chan RWS
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation.
Investigator(s):Ng EHY, Yeung WSB, Chan RWS, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2017


Project Title:The regulatory role of placenta-derived extracellular vesicles on the differentiation and functions of human decidual macrophages
Investigator(s):Ng EHY, Chiu CN, Lee CL
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2018


Project Title:Free Preimplantation Genetic Diagnosis Service for Monogenic Diseases and Translocation Carriers to Prevent Offspring with Severe Medical Conditions
Investigator(s):Ng EHY, Yeung WSB, Chow JFC
Department:Obstetrics & Gynaecology
Source(s) of Funding:S.K. Yee Medical Foundation - General Award
Start Date:04/2018


List of Research Outputs

CHENG H.C., Chan R.W.S., CAO M., Ng E.H.Y. and Yeung W.S.B., An investigation of matrix metalloproteinase 3 derived from myometrial cells on endometrial mesenchymal stem-like cells maintenance, 50th Society For The Study Of Reproduction. 2017, 63.
Chan C.H.Y., Lau H.P., Tam M.Y.J., WONG S. and Ng E.H.Y., Intrapersonal and interpersonal predictors of fertility-related distress - constructing holistic interventions for women undergoing ART treatments., 33rd Annual Meeting of European Society of Human Reproduction and Embryology, Geneva, Switzerland. 2017.
Chan Y.L.D., Lam K.W., Lau Y.L.E., Yeung W.S.B. and Ng E.H.Y., Human varicella zoster virus is not present in the semen of a man affected by chickenpox during the in vitro fertilisation of his wife, Andrologia. 2017, 49: e12822.
Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145.
Cheung K.W., Seto T.Y.M. and Ng E.H.Y., Tenofovir to Prevent Perinatal Transmission of Hepatitis B, New England Journal of Medicine. 2018, 378: 2348-2350.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau Y.L.E. and Ng E.H.Y., Evaluation of preimplantation genetic testing for chromosomal structural rearrangement by a commonly used next generation sequencing workflow, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018, 224: 66-73.
Iliodromiti S., Salje B., Dewailly D., Fairburn C., Fanchin R., Fleming R., Li R.H.W., Lukaszuk K., Ng E.H.Y., Pigny P., Tadros T., van Helden J., Weiskirchen R. and Nelson S.M., Non-equivalence of anti-Müllerian hormone automated assays—clinical implications for use as a companion diagnostic for individualised gonadotrophin dosing, Human Reproduction. 2017, 32: 1710-1715.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The regulatory roles of decidual glycodelin-A on trophoblast and immune cell functions during early pregnancy., The 38th Annual Meeting of the American Society for Reproductive Immunology. 2018 Jun 28-July 1, Shanghai, China.. 2018.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The roles of decidual glycodelin-A in placental development and fetomaternal tolerance during early pregnancy., 1st Asia Pacific Reproductive Immunology Forum. 2017 Dec 9, Seoul, Korea.. 2017.
Li H.E., Li L.U., Lu X.I.A.N.G., Sun X.I.A.O.X.I. and Ng E.H.Y., Comparison of the effect of immediate versus delayed transfer following a stimulated IVF cycle on the ongoing pregnancy rate of frozen-thawed embryo transfer cycles: a study protocol for a randomised controlled trial, BMJ Open. 2018, 8: e020507.
Li J., Ng E.H.Y., Stener-Victorin E., Hu Z., Shao X., Wang H., Li M., Lai M., Xie C., Su N., Yu C., Liu J., Wu T. and Ma H., Acupuncture treatment for insulin sensitivity of women with polycystic ovary syndrome and insulin resistance: a study protocol for a randomized controlled trial, Trials. 2017, 18.
Li J., Wu Q., Wu X.K., Zhou Z.M., Fu P., Chen X.H., Yan Y., Wang X., Yang Z.W., Li W.L., Stener-Victorin E., Legro R.S., Ng E.H.Y., Zhang H., Mol B.W.J. and Wang C.C., Effect of exposure to second-hand smoke from husbands on biochemical hyperandrogenism, metabolic syndrome and conception rates in women with polycystic ovary syndrome undergoing ovulation induction, Human Reproduction. 2018, 33: 617-625.
Li R.H.W., Li Y.X., Li T.T., Fan H.J., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Effect of ulipristal acetate and mifepristone at emergency contraception dose on the embryo-endometrial attachment using an in vitro human trophoblastic spheroid and endometrial cell co-culture model, Human Reproduction. 2017, 32: 2414-2422.
Li R.H.W., Lo S.T.S., Wong C.Y.G., Kok W.M., Chan C.H.Y. and Ng E.H.Y., Effects of sexual dysfunction on fertility-related quality of life of oneself and the partner in infertile Chinese couples, 15th Congress of the European Society of Contraception and Reproductive Health. 2018.
Li R.H.W., Lam K.S.L., Tam S., Wong E., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction Of Metabolically Unhealthy Phenotype By The Visceral Accumulation Index, Lipid Accumulation Index And Triglyceride-glucose Index In Chinese Women With Polycystic Ovary Syndrome, European Society of Human Reproduction and Embryology Annual Meeting, 2-5 Jul 2017, Geneva, Switzerland. 2017.
Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of incident metabolic syndrome and dysglycaemia by adiposity and insulin resistance indices in Chinese women with polycystic ovary syndrome: a 4-year longitudinal study, 100th Annual Meeting & Expo of the Endocrine Society. 2018.
Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of metabolically unhealthy phenotype by the visceral adiposity index, lipid accumulation product and triglyceride-glucose index in Chinese women with polycystic ovary syndrome, 33rd Annual Meeting, European Society of Human Reproduction and Embryology. 2017.
Seto T.Y.M., Cheung K.W., TK L.O. and Ng E.H.Y., Pregnancy outcomes of women randomized to receive real versus placebo acupuncture on the day of fresh or frozen-thawed embryo transfer, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2017, 218: 119-122.
Wong Q.H.Y., Yeung T.W.Y., Yung S.F.S., Ko K.Y.J., Li R.H.W. and Ng E.H.Y., The effect of 12-month dehydroepiandrosterone supplementation on the menstrual pattern, ovarian reserve markers, and safety profile in women with premature ovarian insufficiency, Journal of Assisted Reproduction and Genetics. 2018, 35: 857-862.
YAO H., Chan C.H.Y., Tam M.Y.J., Lau H.P. and Ng E.H.Y., Mental health profile of infertile women seeking ART in China., 33rd Annual Meeting of European Society of Human Reproduction and Embryology, Geneva, Switzerland. 2017.
Yung S.F.S., Chan K.W., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps, 33rd Annual Meeting of the European Society of Human Reproduction and Embryology (Human Reproduction). Oxford University Press, 2017, 32, Issue suppl_1: i331-2.


Researcher : Ng TY
Project Title:A propective randomised controlled trial: prevention of lymphedema by omentoplasty after pelvic lymphadenectomy
Investigator(s):Ng TY, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Low Budget High Impact Programme
Start Date:11/2001




Researcher : Ngai CSW
Project Title:Vaginal misoprostol for first trimester termination of pregnancy prior to 9 weeks of gestation
Investigator(s):Ngai CSW, Tang FOS, Chan YM, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Health Services Research Fund - Full Grants
Start Date:05/1999


Project Title:Cervical assessment in prediction of preterm labour: is three-dimensional ultrasonography a better choice?
Investigator(s):Ngai CSW, Lao THT, Chen M, Leung KY
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:Multiple pregnancy and gestational diabetes: a physiological response or a pathologic condition?
Investigator(s):Ngai CSW, Lao THT, Leung WC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:The XIXth Asian and Oceanic Congress of Obstetrics & Gynaecology Should We Screen Sexually Transmitted Diseases for Women Requesting for Termination of Pregnancy?
Investigator(s):Ngai CSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:10/2005




Researcher : Ngan HYS
Project Title:High dose cis-platinum and cyclophosphamide vs taxol in ovarian cancer
Investigator(s):Ngan HYS, Wong LCR
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:07/1994


Project Title:Investigation on the oncogenic roles of HPV-E6 and mCRPs in cervical cancer cells
Investigator(s):Ngan HYS, Leung THY, Siu KY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2016
Completion Date:03/2018


Project Title:Functional characterization of the roles of NR4A2 in cervical cancer cells
Investigator(s):Ngan HYS, Leung THY, Siu KY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:04/2017


Project Title:Investigation on the association of CD109 and STAT3 activity in regulating cervical cancer cell metastasis
Investigator(s):Ngan HYS, Leung THY, Siu KY, Chan KKL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:05/2018


List of Research Outputs

CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436.
CHEN K., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness via targeting GRB7, Cancer Research. 2017, 77: LB-324-LB-324.
CHEN R., Ngan H.Y.S. and Chan D.W., Targeting lipid metabolism eradicates peritoneal metastases of ovarian cancer, AACR Annual Meeting 2018, April 14-18, 2018 McCormick Place North/South Chicago, Illinois. 2018.
Chan D.W., CHEN R., Yung M.H. and Ngan H.Y.S., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade , Cold Spring Harbour Asia organized "conference on Inflammation: Basic Mechanisms & Relevant Diseases". 2017.
Chan D.W., CHEN R. and Ngan H.Y.S., Targeting lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases of ovarian cancer, Cold Spring Harbour Asia: Cancer & Metabolism. 26-30 March, 2018 Suzhou, China. 2018.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Wang Y., Leung T.H.Y., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis, BMC Cancer. 2017.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Leung T.H.Y. and Ngan H.Y.S., Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer., Cancer Cell Int.. 2018, 18.
Garland S.M., Pitisuttithum P., Ngan H.Y.S., Cho C.H., Lee C.Y., Chen C.A., Yang Y.C., Chu T.Y., Twu N.F., Samakoses R., Takeuchi Y., Cheung T.H., Kim S.C., Huang L.M., Kim B.G., Kim Y.T., Kim K.H., Song Y.S., Lalwani S., Kang J.H., Sakamoto M., Ryu H.S., Bhatla N., Yoshikawa H., Ellison M.C., Han S.R., Moeller E., Murata S., Ritter M., Sawata M., Shields C., Walia A., Perez G. and Luxembourg A., Immunogenicity, and Safety of a 9-Valent Human Papillomavirus Vaccine: Subgroup Analysis of Participants From Asian Countries, J Infect Dis. 2018, 218(1): 95-108.
Kwong A., HO C.W.J., Shin V.Y., Kurian A.W., Tai E., Esserman L.J., Weizel J.N., Lin P.H., Field M., Domcheck S.M., Ngan H.Y.S., Ma E.S.K., Chan T.L. and Ford J.M., Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels, Oncotarget. 2018, 9(8): 7832-7843.
LEUNG L.L., Yung M.H., Ngan H.Y.S. and Chan D.W., The secretary miR-141 facilitates ovarian cancer metastasis through reprogramming stromal fibroblast cells in pre-metastatic niches formation, the 25th Biennial Congress of the European Association for Cancer Research (EACR25). 2018.
Lam W.L., Yeung W.F., Wong M.K., Cheung C.W., Chan K.K.L., Ngan H.Y.S., Wong C.K.H., Chen H. and Lao L., Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial, Trials. 2018, 19: 8.
Leung T.H.Y., Tang W.M., Siu K.Y., Chan D.W., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., HPV-E6 protein enriches the CD55(+) population in cervical cancer cells promoting radio-resistance and cancer aggressiveness, The Journal of Pathology. 2017.
Mak C.M., Law E.C., Lee H.H., Siu W.K., Chow K.M., Au Yeung S.K., Ngan H.Y.S., Tse N.K., Kwong N.S., Chan G.C., Lee K.W., Chan W.P., Wong S.F., Tang M.H., Kan A.S., Hui A.P., So P.L., Shek C.C., Lee R.S., Wong K.Y., Yau E.K., Poon K.H., Siu S., Poon G.W., Kwok A.M., Ng J.W., Yim V.C., Ma G.G., Chu C.H., Tong T.Y., Chong Y.K., Chen S.P., Ching C.K., Chan A.O., Tam S., Lau R.L., Ng W.F., Lee K.C., Chan A.Y. and Lam C.W., The first pilot study of expanded newborn screening for inborn errors of metabolism and survey of related knowledge and opinions of health care professionals in Hong Kong, Hong Kong Med J. 2018, 24(3): 226-237.
Meng Y., Chen C.W., Yung M.H., Sun W., Sun J., Li Z., Li J., Li Z., Zhou W., Liu S., Cheung A.N.Y., Ngan H.Y.S., Braisted J.C., Kai Y., Peng W., Tzatsos A., Li Y., Dai Z., Zheng W., Chan D.W. and Zhu W., DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer, Cancer Letters. 2018.
Ngan H.Y.S., Advances in Cervical Cancer Screening Beyond the Pap Smear, RCOG World Congress 2018, Singapore, March 21-24. 2018.
Ngan H.Y.S., Can we be less radical in the treatment of cervical cancer , 2017 Annual Meeting of Chinese Society of Clinical Oncology (CSCO), Xiamen, PRC, September 26-30. 2017.
Ngan H.Y.S., Cervical Cancer Prevention and Control, 2018 New Advances in Management of Cervical Diseases Workshop, Wenzhou, China, April 21. 2018.
Ngan H.Y.S., Cervical Cancer Prevention and Control, The 2nd HN -SCCP cervical cancer precancerous lesion and cervical cancer hotspot conference, Xiangya Hospital, Central South University, Hunan, China, May 5-6. 2018.
Ngan H.Y.S., Cervical cancer screening in Hong Kong, 5th Biennial Meeting of Asian Society of .Gynecologic Oncology, Tokyo, Japan. 2017.
Ngan H.Y.S., Complications of Robotic Surgery, 3rd Asian Congress of Robotic and Endoscopic Surgery, Taipei, Taiwan, November 24- 26. 2017.
Ngan H.Y.S., Current Advancements of PARP inhibitor in Europe/HK, Ovarian & Breast Cancer – Advancements in Diagnostic & Therapeutic Landscape Exchange Meeting, Hong Kong, 27 January. 2018.
Ngan H.Y.S., Detection and management of CIN in AOGIN countries, Asia-Oceania Research Organisation in Genital Infection and Neoplasia (“AOGIN”) 2016 Congress - Science, prevention, diagnosis and therapy on HPV related cancers, Tokyo, Japan, October 18-19. 2017.
Ngan H.Y.S., Endometrial Cancer – Current Management , Malaysian International Scientific Congress of O&G: Where Advanced Technology, Scientific Evidence & Clinical Skills Meet, Penang, Malaysia, March 25. 2018.
Ngan H.Y.S., Gynaecology Cancer, Li Shu Pui Symposium 2017, Hong Kong Sanatorium & Hospital, September 3. 2017.
Ngan H.Y.S., How to decide which treatment is appropriate in cervical cancer , The 4th Chinese Society of Colposcopy and Cervical Pathology (CSCCP) conference, Shenzhen China, May 24-27. 2018.
Ngan H.Y.S., How to train a gynaecological oncologist, 第十五届妇科恶性肿瘤规范化诊治及新进展学习班暨首届广东省遗传性妇科肿瘤高峰 论坛, Guangzhou, China, December 15. 2017.
Ngan H.Y.S., Implementing HPV vaccination in ASEAN countries, CICAMS-IARC Joint Training Course on ‘Planning & Implementing Cancer Control Program’, Shenzhen, China, October 23. 2017.
Ngan H.Y.S., Maintenance Therapy in Ovarian Cancer , The First Ovarian Cancer Sumit 2018, Beijing, China, June 30. 2018.
Ngan H.Y.S., Prophylactic HPV vaccine and cervical cancer prevention, HPV and Cervical Cancer Prevention Training Class, Shenzhen Maternity & Child Healthcare Hospital, Shenzhen, PRC, July 1. 2017.
Ngan H.Y.S., Chan K.K.L., Tse K.Y., Chu M.Y.M., Ngu S.F. and Hui S., QMH/TYH Outstanding Teams (Walk Together with One Heart), HKWC cum QMH/TYH Outstanding Staff & Teams Award and Young Achiever Award for 2018. 2018.
Ngan H.Y.S., Robotic Assisted Radical Hysterectomy, 3rd Asian Congress of Robotic and Endoscopic Surgery, Taipei, Taiwan, November 24- 26. 2017.
Ngan H.Y.S. and Lim P.C., Robotic surgery in gynecology, Best Pract Res Clin Obstet Gynaecol.. 2017.
Ngan H.Y.S., The training of a gynaecological oncologist, Chongqing, China, March 30. 第十五届妇科肿瘤学 术大会暨中国妇科肿 瘤青年医师高峰论坛, 2018.
Ngan H.Y.S., Updates on Management Options for Gestational Trophoblastic Disease , RCOG World Congress 2018, Singapore, March 21-24. 2018.
Ngan H.Y.S., Updates on the management of Gestational Trophoblastic Diseases, Malaysian International Scientific Congress of O&G: Where Advanced Technology, Scientific Evidence & Clinical Skills Meet, Penang, Malaysia, March 25. 2018.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Bevacizumab in Epithelial Ovarian, Fallopian Tube and Primary Peritoneal Cancer: A Single Centre Experience, 20th International Meeting of The European Society of Gynaecological Oncology (ESGO 2017). 2017.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Recurrent Gestational Trophoblastic Neoplasia with Pulmonary Metastatic Choriocarcinoma: A Case Report, XIX World Congress on Gestational Trophoblastic Diseases, Amsterdam, Netherlands . 2017.
Ngu S.F., Chu M.Y.M., Tse K.Y., Chan K.K.L., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Role Of Lymphadenectomy And Vincristine, Actinomycin-D, and Cyclophosphamide Chemotherapy in Malignant Ovarian Germ Cell Tumors, European Journal of Gynaecological Oncology. 2018, 39(1): 63-69.
Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018.
Tse K.Y., Wei N., Kwan T.T.C., Chu M.Y.M., Ngu S.F., Chan K.K.L. and Ngan H.Y.S., Quality-of-life of ovarian cancer patients with prolonged use of chemotherapy - a prospective comparative quantitative and qualitative study, Poster presentation: 20thInternational Meeting of the European Society of Gynaecological Oncology; Vienna, Austria; 4 – 7 Nov 2017.
Tse K.Y., Ngan H.Y.S. and Lim P.C., Robot-assisted gynaecological cancer surgery—complications and prevention, Best Practice & Research Clinical Obstetrics & Gynaecology. 2017, 45: 94-106.
Wong J.H., Sze S.C.W., Ng T.B., Cheung R.C.F., Tam C., Zhang K.Y., Dan X., Chan Y.S., Cho W.C.S., Ng C.C.W., Waye M.M.Y., Liang W., Zhang J., Yang J., Ye X., Lin J., Ye X.J., Wang H., Liu F., Chan D.W., Ngan H.Y.S., Sha O., Li G., Tse R., Tse T.K. and Chan H., Apoptosis and anti-cancer drug discovery: the power of medicinal fungi and plants, In: Atta-ur-Rahman, FRS, Current Medicinal Chemistry. Bentham Science, 2017, 24: E-pub Abstract Ahead of Print.
Xiang L., Jiang W., Ye S., He T., Pei X., Li J., Chan D.W., Ngan H.Y.S., Li F., Tao P., Shen X., Zhou X., Wu X., Yang G. and Yang H., ERBB2 mutation: A promising target in non-squamous cervical cancer, Gynecologic Oncology. 2018.
Yung M.H., Ngan H.Y.S. and Chan D.W., Cold Spring Harbour Asia conference on "Inflammation: Basic Mechanisms & Relevant Diseases". 2017.
Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285.
Zhou W., Sun W., Yung M.H., Dai S., Cai Y., Chen C.W., Meng Y., Lee J.B., Braisted J.C., Xu Y., Southall N.T., Shinn P., Huang X., Song Z., Chen X., Kai Y., Cai X., Li Z., Hao Q., Cheung A.N.Y., Ngan H.Y.S., Liu S., Barak S., Hao J., Dai Z., Tzatsos A., Peng W., Pei H., Han Z., Chan D.W., Zheng W. and Zhu W., Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance, Oncogene. 2018.


Researcher : Ngu SF
Project Title:Investigation of the Synergistic Anticancer Effect of Gedatolisib (PKI-587, PF-05212384) and Cisplatin in Ovarian Clear Cell Carcinoma (OCCC)
Investigator(s):Ngu SF, Chan DW, Ngan HYS
Department:Obstetrics & Gynaecology
Source(s) of Funding:Seed Fund for Basic Research
Start Date:03/2017


Project Title:20th Biennial International Meeting of the European Society of Gynaecological Oncology; Bevacizumab in epithelial ovarian, fallopian tube and primary peritoneal cancer: a single centre experience
Investigator(s):Ngu SF
Department:Obstetrics & Gynaecology
Source(s) of Funding:URC/CRCG - Conference Support for Teaching Staff
Start Date:11/2017
Completion Date:11/2017


List of Research Outputs

CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436.
Crawford R., Newcombe B., Bolton H., Ngu S.F., Freeman S., Addley H., Jimenez-Linan M., Armstrong R. and Tischkowitz M., The Ten Year Experience of A Regional Specialist Gynaecology Cancer Genetics Clinic with Lynch Syndrome, 20th International Meeting of The European Society of Gynaecological Oncology (ESGO 2017). 2017.
Ngan H.Y.S., Chan K.K.L., Tse K.Y., Chu M.Y.M., Ngu S.F. and Hui S., QMH/TYH Outstanding Teams (Walk Together with One Heart), HKWC cum QMH/TYH Outstanding Staff & Teams Award and Young Achiever Award for 2018. 2018.
Ngu S.F. and Chan K.K.L., Abdominal Hysterectomy: Instrumentation and Apparatuses, In: Ibrahim Alkatout, Liselotte Mettler, Hysterectomy A Comprehensive Surgical Approach. Springer, Cham, 2018, 1049-1057.
Ngu S.F. and Chan K.K.L., Abdominal Hysterectomy: Preparation, In: Ibrahim Alkatout, Liselotte Mettler, Hysterectomy A Comprehensive Surgical Approach. Springer, Cham, 2018, 1041-1047.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Bevacizumab in Epithelial Ovarian, Fallopian Tube and Primary Peritoneal Cancer: A Single Centre Experience, 20th International Meeting of The European Society of Gynaecological Oncology (ESGO 2017). 2017.
Ngu S.F., Diagnosis & Management Of Abnormal Ps & Cin In Adolescent, Hospital Authority Obstetrics and Gynaecology Commissioned Training on 2017/18. 2018.
Ngu S.F., Lynch Syndrome, Grand Round, University of Cambridge, School of Clinical Medicine. 2017.
Ngu S.F., Bolton H., Riddick A., Freeman S., Ahmed R. and Shafi M., Ovarian Carcinosarcoma with Perirenal Metastasis: A Case Report, 20th International Meeting of The European Society of Gynaecological Oncology (ESGO 2017). 2017.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Recurrent Gestational Trophoblastic Neoplasia with Pulmonary Metastatic Choriocarcinoma: A Case Report, XIX World Congress on Gestational Trophoblastic Diseases, Amsterdam, Netherlands . 2017.
Ngu S.F., Chu M.Y.M., Tse K.Y., Chan K.K.L., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Role Of Lymphadenectomy And Vincristine, Actinomycin-D, and Cyclophosphamide Chemotherapy in Malignant Ovarian Germ Cell Tumors, European Journal of Gynaecological Oncology. 2018, 39(1): 63-69.
Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018.
Tse K.Y., Wei N., Kwan T.T.C., Chu M.Y.M., Ngu S.F., Chan K.K.L. and Ngan H.Y.S., Quality-of-life of ovarian cancer patients with prolonged use of chemotherapy - a prospective comparative quantitative and qualitative study, Poster presentation: 20thInternational Meeting of the European Society of Gynaecological Oncology; Vienna, Austria; 4 – 7 Nov 2017.
Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285.


Researcher : Ong CYT
Project Title:To determine the correlation of changes in maternal levels of pregnancy-associated plasma protein A (PAPP-A) and free [beta] human chorionic gonadotrophin (F[beta]-hCG) with placental development and fetal outcomes
Investigator(s):Ong CYT, Lao THT, Leung WC, Leung KY, Lam HSW
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2003


Project Title:First trimester prediction of fetal α-thalassaemia-1 with maternal serum markers, nuchal translucency measurement and three dimentional ultrasound measurement of placental volume
Investigator(s):Ong CYT, Chen M, Leung KY, Tang MHY, Lee CP
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:11/2004


Project Title:Maternal serum level of ADAM 12 as an early marker of trisomy 21, trisomy 13 and trisomy 18
Investigator(s):Ong CYT, Lee CP, Lau ETK
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:01/2007




Researcher : Pang RTK
Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang TKR, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007




Researcher : Pang TKR
Project Title:A comparative study of the extracellular matrix molecules from feeder cells supporting the growth of human embryonic stem cells
Investigator(s):Pang TKR, Yeung WSB, Lee CYL
Department:Obstetrics & Gynaecology
Source(s) of Funding:Small Project Funding
Start Date:09/2007




Researcher : Pun TC
List of Research Outputs

Pun T.C., Vaginal hysterectomy – the way forward, HKCOG 30th Anniversary Symposium. 2018.


Researcher : Seto TYM
List of Research Outputs

Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145.
Cheung K.W., Seto T.Y.M. and Ng E.H.Y., Tenofovir to Prevent Perinatal Transmission of Hepatitis B, New England Journal of Medicine. 2018, 378: 2348-2350.
Seto T.Y.M., Cheung K.W., TK L.O. and Ng E.H.Y., Pregnancy outcomes of women randomized to receive real versus placebo acupuncture on the day of fresh or frozen-thawed embryo transfer, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2017, 218: 119-122.


Researcher : Shek NWM
List of Research Outputs

Shek N.W.M., Clinical practice of caesarean section revisited: present and future, Hong Kong Medical Journal. 2017, 324-325.


Researcher : Siu KY
Project Title:Effects of folate and folate receptor on ovarian and endometrial cancer: an in vitro study
Investigator(s):Siu KY, Cheung ANY
Department:Pathology
Source(s) of Funding:American Institute for Cancer Research (AICR) - General Award
Start Date:07/2006


Project Title:p21-activated kinase 4: a prognostic and therapeutic target for ovarian carcinoma?
Investigator(s):Siu KY, Cheung ANY, Ngan HYS
Department:Pathology
Source(s) of Funding:The Hong Kong Anti-Cancer Society (HKACS) - General Award
Start Date:10/2007


List of Research Outputs

Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Wang Y., Leung T.H.Y., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis, BMC Cancer. 2017.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Leung T.H.Y. and Ngan H.Y.S., Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer., Cancer Cell Int.. 2018, 18.
Leung T.H.Y., Tang W.M., Siu K.Y., Chan D.W., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., HPV-E6 protein enriches the CD55(+) population in cervical cancer cells promoting radio-resistance and cancer aggressiveness, The Journal of Pathology. 2017.


Researcher : Tang FOS
Project Title:A prospective randomized comparison of sublingual and vaginal misoprostol in termination of pregnancy in the second trimester
Investigator(s):Tang FOS, Ho PC
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:10/2000




Researcher : Tang GWK
Project Title:A cross sectional health care study of Chinese perimenopausal women in Hong Kong
Investigator(s):Tang WKG
Department:Obstetrics & Gynaecology
Source(s) of Funding:Other Funding Scheme
Start Date:01/1993




Researcher : Tang MHY
List of Research Outputs

Cheng H.Y.H., Kan S.Y.A., Hui P.W., Lee C.P. and Tang M.H.Y., Bridging the gap from prenatal karyotyping to whole-genome array comparative genomic hybridization in Hong Kong: survey on knowledge and acceptance of health-care providers and pregnant women, Archives of Gynecology and Obstetrics. 2017, 296: 1109-1116.
Kan S.Y.A., Lau E.T.K., So C.H., Chan W.P., Wong W.C., Lee K.C., Pertile M.D. and Tang M.H.Y., A fetus coexisting with a complete hydatidiform mole with trisomy 9 of maternal origin, Journal of Obstetrics and Gynaecology Research. 2018, 44: 955-959.
Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8.
So P.L., Cheng Y.K.Y., Cheuk K.Y., Chiu W.K., Mak S.L., Mok S.L., Lo T.K., Yung W.K., Lo F.M., Chung B.H.Y., Kan S.Y.A., Lee C.P. and Tang M.H.Y., Parental decisions following prenatal diagnosis of sex chromosome aneuploidy in Hong Kong, The Journal of Obstetrics and Gynaecology Research. 2017, 43(12): 1821-1829.


Researcher : Tang WF
List of Research Outputs

Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8.


Researcher : Tang WM
List of Research Outputs

Leung T.H.Y., Tang W.M., Siu K.Y., Chan D.W., Chan K.K.L., Cheung A.N.Y. and Ngan H.Y.S., HPV-E6 protein enriches the CD55(+) population in cervical cancer cells promoting radio-resistance and cancer aggressiveness, The Journal of Pathology. 2017.
Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285.


Researcher : Tse KY
List of Research Outputs

Chan K.K., Wong G.W., Wong E.S.Y., Chan K.K.L., Ip P.C.P., Tse K.Y. and Cheung A.N.Y., Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma, International Journal of Cancer. 2018.
Ip P.C.P., YU Y., Cheung C.L., Cheuk W., Cheung E., Wong W.C., Lee V., Chan W.K. and Tse K.Y., Female Genital melanomas: A clinicopathologic and PD-L1 expression study, The United States and Canadian Academy of Pathology 107th Annual Meeting . 2018.
Ngan H.Y.S., Chan K.K.L., Tse K.Y., Chu M.Y.M., Ngu S.F. and Hui S., QMH/TYH Outstanding Teams (Walk Together with One Heart), HKWC cum QMH/TYH Outstanding Staff & Teams Award and Young Achiever Award for 2018. 2018.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Bevacizumab in Epithelial Ovarian, Fallopian Tube and Primary Peritoneal Cancer: A Single Centre Experience, 20th International Meeting of The European Society of Gynaecological Oncology (ESGO 2017). 2017.
Ngu S.F., Chan K.K.L., Tse K.Y., Chu M.Y.M. and Ngan H.Y.S., Recurrent Gestational Trophoblastic Neoplasia with Pulmonary Metastatic Choriocarcinoma: A Case Report, XIX World Congress on Gestational Trophoblastic Diseases, Amsterdam, Netherlands . 2017.
Ngu S.F., Chu M.Y.M., Tse K.Y., Chan K.K.L., Ip P.C.P., Cheung A.N.Y. and Ngan H.Y.S., Role Of Lymphadenectomy And Vincristine, Actinomycin-D, and Cyclophosphamide Chemotherapy in Malignant Ovarian Germ Cell Tumors, European Journal of Gynaecological Oncology. 2018, 39(1): 63-69.
Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018.
Tse K.Y., Wei N., Kwan T.T.C., Chu M.Y.M., Ngu S.F., Chan K.K.L. and Ngan H.Y.S., Quality-of-life of ovarian cancer patients with prolonged use of chemotherapy - a prospective comparative quantitative and qualitative study, Poster presentation: 20thInternational Meeting of the European Society of Gynaecological Oncology; Vienna, Austria; 4 – 7 Nov 2017.
Tse K.Y., Ngan H.Y.S. and Lim P.C., Robot-assisted gynaecological cancer surgery—complications and prevention, Best Practice & Research Clinical Obstetrics & Gynaecology. 2017, 45: 94-106.
Tse K.Y., Surgicopathological prognostic parameters in uterine leiomyosarcoma – an Asian Gynecologic Oncology Group and collaborator study, Poster presentation: 5thBiennial Meeting of Asian Society of Gynecologic Society; Tokyo, Japan; 30 Nov – 2 Dec 2017.


Researcher : VIJAYAN M
List of Research Outputs

Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The regulatory roles of decidual glycodelin-A on trophoblast and immune cell functions during early pregnancy., The 38th Annual Meeting of the American Society for Reproductive Immunology. 2018 Jun 28-July 1, Shanghai, China.. 2018.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The roles of decidual glycodelin-A in placental development and fetomaternal tolerance during early pregnancy., 1st Asia Pacific Reproductive Immunology Forum. 2017 Dec 9, Seoul, Korea.. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., Global Health Travel Awards: Decidual glycodelin-A drives human monocyte to macrophage differentiation and functions via siglec-7., Maternal‐Fetal Crosstalk: Harmony vs. Conflict. 2017 Oct 4-8, Westin Washington, DC City Center, Washington, DC, USA.. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., The Role of Decidual Glycodelin-A in regulating Macrophage Functions. , Immunological Aspects in Andrology. 2017 Sept 9, Shenzhen, China.. 2017.
Vijayan M., Global Health Travel Award, Keystone symposia /Melinda and Bill Gates Foundation. 2017.


Researcher : Vijayan M
List of Research Outputs

Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The regulatory roles of decidual glycodelin-A on trophoblast and immune cell functions during early pregnancy., The 38th Annual Meeting of the American Society for Reproductive Immunology. 2018 Jun 28-July 1, Shanghai, China.. 2018.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The roles of decidual glycodelin-A in placental development and fetomaternal tolerance during early pregnancy., 1st Asia Pacific Reproductive Immunology Forum. 2017 Dec 9, Seoul, Korea.. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., Global Health Travel Awards: Decidual glycodelin-A drives human monocyte to macrophage differentiation and functions via siglec-7., Maternal‐Fetal Crosstalk: Harmony vs. Conflict. 2017 Oct 4-8, Westin Washington, DC City Center, Washington, DC, USA.. 2017.
VIJAYAN M., Lee C.L., Lee C.K.F. and Chiu C.N., The Role of Decidual Glycodelin-A in regulating Macrophage Functions. , Immunological Aspects in Andrology. 2017 Sept 9, Shenzhen, China.. 2017.
Vijayan M., Global Health Travel Award, Keystone symposia /Melinda and Bill Gates Foundation. 2017.


Researcher : WANG J
List of Research Outputs

Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Wang Y., Leung T.H.Y., Liu S., Cheung A.N.Y. and Ngan H.Y.S., Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis, BMC Cancer. 2017.
Chan K.K.L., Siu K.Y., JIANG Y., WANG J., Leung T.H.Y. and Ngan H.Y.S., Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer., Cancer Cell Int.. 2018, 18.


Researcher : WANG X
List of Research Outputs

WANG X., Lee C.L., Li R.H.W. and Chiu C.N., Best Oral Presentation Award: Adrenomedullin regulates macrophage functions in inflammation-induced tubal ectopic pregnancy, The Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction. 2017 Nov 12 Hong Kong.. 2017.


Researcher : WANG Z
List of Research Outputs

WANG Z., Kottawatta K...S...A..., Kodithuwakku S...P... and Lee C.K.F., Effect of Fungicide Mancozeb and its metabolite Ethylenethiourea (ETU) on spheroid attachment and transcriptomic changes in Ishikawa cells, Oral presentation. O3. The Hong Kong Society of Endocrinology, Metabolism and Reproduction 34rd Annual Scientific Meeting, 12 Nov 2017, Hong Kong. 2017.
WANG Z., Kottawatta K...S...A..., Kodithuwakku S...P... and Lee C.K.F., Exposure to Mancozeb impairs embryo implantation via disrupting embryo- epithelium interaction in vitro trophoblast/endometrial cells co-culture model, P-442. European Society of Human reproduction and embryology, 33rd Annual Meeting.2-5 July 2017, Geneva, Switzerland. 2017.
WANG Z., Kottawatta K...S...A..., Kodithuwakku S...P... and Lee C.K.F., The effect of Mancozeb on spheroid attachment in vitro co-culture model and gene expression profiling of Ishikawa cells, P5.09. The University of Hong Kong, Li Ka Shing Faculty of Medicine 22nd Research Postgraduate Symposium.6-7 Dec 2017, Hong Kong, China. 2017.


Researcher : Wai KOJ
List of Research Outputs

Yeo S., Jain P., Wai K.O.J., Chia B.K., Yeo G.S.H. and Mathur M., The Effect of a Raised BMI on Surgical Morbidity in Women Undergoing Caesarean Section - a Pilot Study, Singapore Journal of Obstetrics & Gynaecology. 2017, 48: 20-28.


Researcher : Wei N
List of Research Outputs

Tse K.Y., Wei N., Kwan T.T.C., Chu M.Y.M., Ngu S.F., Chan K.K.L. and Ngan H.Y.S., Quality-of-life of ovarian cancer patients with prolonged use of chemotherapy - a prospective comparative quantitative and qualitative study, Poster presentation: 20thInternational Meeting of the European Society of Gynaecological Oncology; Vienna, Austria; 4 – 7 Nov 2017.


Researcher : Wong CYG
List of Research Outputs

Li R.H.W., Lo S.T.S., Wong C.Y.G., Kok W.M., Chan C.H.Y. and Ng E.H.Y., Effects of sexual dysfunction on fertility-related quality of life of oneself and the partner in infertile Chinese couples, 15th Congress of the European Society of Contraception and Reproductive Health. 2018.


Researcher : Wong E
List of Research Outputs

Li R.H.W., Lam K.S.L., Tam S., Wong E., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction Of Metabolically Unhealthy Phenotype By The Visceral Accumulation Index, Lipid Accumulation Index And Triglyceride-glucose Index In Chinese Women With Polycystic Ovary Syndrome, European Society of Human Reproduction and Embryology Annual Meeting, 2-5 Jul 2017, Geneva, Switzerland. 2017.


Researcher : Yeung WSB
Project Title:The conserved functions of let-7 in embryonic diapause
Investigator(s):Yeung WSB, Liu W, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:National Natural Science Foundation of China (NSFC) - General Program
Start Date:01/2015


Project Title:Polyamine/Let-7 signaling in embryo implantation and diapause
Investigator(s):Yeung WSB, Lee CKF, Liu W
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2016


Project Title:The action of microRNA let-7 on blastocyst formation in mice
Investigator(s):Yeung WSB, Liu W, Lee CYL, Pang TKR
Department:Obstetrics & Gynaecology
Source(s) of Funding:General Research Fund (GRF)
Start Date:01/2018


List of Research Outputs

CHENG H.C., Chan R.W.S., CAO M., Ng E.H.Y. and Yeung W.S.B., An investigation of matrix metalloproteinase 3 derived from myometrial cells on endometrial mesenchymal stem-like cells maintenance, 50th Society For The Study Of Reproduction. 2017, 63.
Chan Y.L.D., Lam K.W., Lau Y.L.E., Yeung W.S.B. and Ng E.H.Y., Human varicella zoster virus is not present in the semen of a man affected by chickenpox during the in vitro fertilisation of his wife, Andrologia. 2017, 49: e12822.
Chen C.H., Lee C.Y.L., Fong S.W. and Yeung W.S.B., Hyperglycemia impaired early pancreatic differentiation of human embryonic stem cells through aberration of DNA methylation patterns, Society for the Study of Reproduction Annual Meeting 2017.
Chow J.F.C., Yeung W.S.B., Lee V.C.Y., Lau Y.L.E. and Ng E.H.Y., Evaluation of preimplantation genetic testing for chromosomal structural rearrangement by a commonly used next generation sequencing workflow, European Journal of Obstetrics & Gynecology and Reproductive Biology. 2018, 224: 66-73.
Lee C.L., Yeung W.S.B. and Chiu C.N., Glycodelin-A interacts with L-selectin on CD16-CD56bright natural killer cells to induce endothelial cell angiogenesis and trophoblast invasion, 33rd Annual Meeting of European Society of Human Reproduction and Embryology. 2017.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The regulatory roles of decidual glycodelin-A on trophoblast and immune cell functions during early pregnancy., The 38th Annual Meeting of the American Society for Reproductive Immunology. 2018 Jun 28-July 1, Shanghai, China.. 2018.
Lee C.L., VIJAYAN M., Koistinen H., Seppala M., Ng E.H.Y., Yeung W.S.B. and Chiu C.N., The roles of decidual glycodelin-A in placental development and fetomaternal tolerance during early pregnancy., 1st Asia Pacific Reproductive Immunology Forum. 2017 Dec 9, Seoul, Korea.. 2017.
Lee V.C.Y., Chow J.F.C., Yeung W.S.B. and Ho P.C., Preimplantation genetic diagnosis for monogenic diseases, Best Practice & Research Clinical Obstetrics & Gynaecology. 2017, 44: 68-75.
Li R.H.W., Li Y.X., Li T.T., Fan H.J., Ng E.H.Y., Yeung W.S.B., Ho P.C. and Lee C.K.F., Effect of ulipristal acetate and mifepristone at emergency contraception dose on the embryo-endometrial attachment using an in vitro human trophoblastic spheroid and endometrial cell co-culture model, Human Reproduction. 2017, 32: 2414-2422.
Yung S.F.S., Chan K.W., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps, 33rd Annual Meeting of the European Society of Human Reproduction and Embryology (Human Reproduction). Oxford University Press, 2017, 32, Issue suppl_1: i331-2.


Researcher : Yung MH
List of Research Outputs

CHEN K., Liu X., MAK S.L., Yung M.H., Leung T.H.Y., Xu D., Ngu S.F., Chan K.K.L., Yang H.J., Ngan H.Y.S. and Chan D.W., Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways , Theranostics. 2018, 8: 423-436.
Chan D.W., CHEN R., Yung M.H. and Ngan H.Y.S., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade , Cold Spring Harbour Asia organized "conference on Inflammation: Basic Mechanisms & Relevant Diseases". 2017.
LEUNG L.L., Yung M.H., Ngan H.Y.S. and Chan D.W., The secretary miR-141 facilitates ovarian cancer metastasis through reprogramming stromal fibroblast cells in pre-metastatic niches formation, the 25th Biennial Congress of the European Association for Cancer Research (EACR25). 2018.
Meng Y., Chen C.W., Yung M.H., Sun W., Sun J., Li Z., Li J., Li Z., Zhou W., Liu S., Cheung A.N.Y., Ngan H.Y.S., Braisted J.C., Kai Y., Peng W., Tzatsos A., Li Y., Dai Z., Zheng W., Chan D.W. and Zhu W., DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer, Cancer Letters. 2018.
Yung M.H., Ngan H.Y.S. and Chan D.W., Cold Spring Harbour Asia conference on "Inflammation: Basic Mechanisms & Relevant Diseases". 2017.
Yung M.H., Tang W.M., Cai C.H., Leung T.H.Y., Ngu S.F., Chan K.K.L., Xu D., Yang H.U.I.J.U.A.N., Ngan H.Y.S. and Chan D.W., GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade, Theranostics. 2018, 8: 1270-1285.
Zhou W., Sun W., Yung M.H., Dai S., Cai Y., Chen C.W., Meng Y., Lee J.B., Braisted J.C., Xu Y., Southall N.T., Shinn P., Huang X., Song Z., Chen X., Kai Y., Cai X., Li Z., Hao Q., Cheung A.N.Y., Ngan H.Y.S., Liu S., Barak S., Hao J., Dai Z., Tzatsos A., Peng W., Pei H., Han Z., Chan D.W., Zheng W. and Zhu W., Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance, Oncogene. 2018.


Researcher : Yung SFS
List of Research Outputs

Wong Q.H.Y., Yeung T.W.Y., Yung S.F.S., Ko K.Y.J., Li R.H.W. and Ng E.H.Y., The effect of 12-month dehydroepiandrosterone supplementation on the menstrual pattern, ovarian reserve markers, and safety profile in women with premature ovarian insufficiency, Journal of Assisted Reproduction and Genetics. 2018, 35: 857-862.
Yung S.F.S., Chan K.W., Lee C.K.F., Ng E.H.Y. and Yeung W.S.B., Gene expression profiling of human peri-implantation endometria before and after hysteroscopic polypectomy in subfertile patients with endometrial polyps, 33rd Annual Meeting of the European Society of Human Reproduction and Embryology (Human Reproduction). Oxford University Press, 2017, 32, Issue suppl_1: i331-2.


-- End of Listing --