DEPT OF PAEDIATRICS & ADOLESCENT MED
| Researcher : CHAN KWP |
| List of Research Outputs |
| CHAN K.W.P., Geng L., Gao R.Y., Keung W.W.Y. and Li R.A., AAV-mediated conversion of human pluripotent stem cell-derived pacemaker, Biochemical and Biophysical Research Communications. 2017. |
| Lee E.K., Tran D.D., Keung W.W.Y., CHAN K.W.P., Wong G.K., Chan C.W., Costa K.D., Li R.A. and Khine M., Machine Learning of Human Pluripotent Stem Cell-Derived Engineered Cardiac Tissue Contractility for Automated Drug Classification, Stem Cell Reports. 2017. |
| Li R.A., Keung W.W.Y., Cashman T.J., Backeris P.C., Bryce J.V., Bardot E.S., WONG O.T., CHAN K.W.P., Chan C.W.Y. and Costa K.D., Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells, Biomaterials. 2018, 163: 116-127. |
| Researcher : CHEN Q |
| List of Research Outputs |
| CHEN Q., WEN K., LU A., LIU M., NI K., XIANG Z., Liu Y. and Tu W., Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody, Frontiers in Immunology. 2018, 9. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Researcher : Chan GCF |
| Project Title: | Review of local experience in the management of childhood myelodysplastic syndrome |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/2001 |
| Project Title: | Treatment protocol for childhood medulloblastoma in Hong Kong |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/2001 |
| Project Title: | Survey on the prevalence on use of alternative medical treatment in paediatric patients |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 09/2001 |
| Project Title: | Direct generation and functional characterization of human dendritic cells derived from bone marrow cells of leukemic origins |
| Investigator(s): | Chan GCF, Chiu CSW, Ma ESK, Huang F |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/2002 |
| Project Title: | King's/HKU Fellowship Awards 2009-10 |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | King's/HKU Fellowship Awards |
| Start Date: | 09/2009 |
| Project Title: | Molecular diagnosis for Childhood Cancers: Defining the Prognosis and Stratifying the Proper Treatments |
| Investigator(s): | Chan GCF, Tam PKH |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 01/2014 |
| Project Title: | Human Mesenchymal Stem Cells as a Therapeutic Modality for Graft Versus Host Disease Murine Models |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| Project Title: | A two-arm, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of Everolimus (mTOR inhibitor) in pediatric patients with tuberous sclerosis and epilepsy requiring anticonvulsant treatments |
| Investigator(s): | Chan GCF, Yung AWY, Khong PL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 09/2015 |
| Project Title: | The healing effects of mesenchymal stem cell or its soluble factors on cutaneous burn injury |
| Investigator(s): | Chan GCF, Li CB, Chan S |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| Project Title: | Automated bioreactors for expanding and monitoring mesenchymal stem cells |
| Investigator(s): | Chan GCF, Li CB, Deng R |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Matching Grant for Joint Research |
| Start Date: | 10/2016 |
| Project Title: | Investigation of Sustained Expression of Human Factor IX by Genetic Modified Human Mesenchymal Stem Cells both in vivo and in vitro |
| Investigator(s): | Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Providence Foundation Limited |
| Start Date: | 01/2017 |
| Project Title: | Effect of bismuth compound as anti-oxidant for iron overload protection |
| Investigator(s): | Chan GCF, Sun H, Chan S |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 08/2017 |
| Project Title: | Ex vivo of dendritic cell functions uner iron overload conditions in thalassaemia patients |
| Investigator(s): | Chan GCF, Ha SY, Kwong YL, Hwang YYG, Cheuk KLD, Li CB, Mok SP |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 08/2017 |
| List of Research Outputs |
| Chan S. and Chan G.C.F., A novel synthetic compound bismuth zinc citrate could potentially reduce cisplatin induced toxicity without compromising the anticancer effect through enhanced expression of metallothionein and GSH , The 13th Congress of Asian Society for Pediatric Research. 2017. |
| Chan S. and Chan G.C.F., Deferiprone Inhibits Iron Overload-Induced Tissue Factor Bearing Endothelial Microparticle Generation by Inhibition Oxidative Stress Induced Mitochondrial Injury, and Apoptosis, HKPS Joint Annual Research & Scientific Meeting . 2017. |
| Chan S., Lian Q., Cheung Y.F. and Chan G.C.F., Deferiprone inhibits iron overload-induced tissue factor bearing endothelial microparticle generation by inhibition oxidative stress induced mitochondrial injury, and apoptosis, Toxicology and Applied Pharmacology . 2018, 338: 148-158. |
| Deng R., Zhou B., Guan B., Chan G.C.F. and Shen J., Marine algae extract attenuated osteoporosis in OVX mice, enhanced osteogenesis on human mesenchymal stem cells and promoted OPG expression, In: Vincenzo Fogliano, Journal of Functional Foods. ELSEVIER, 2017, 40: 229-237. |
| HO K.Y., Li W.H.C. and Chan G.C.F., Effectiveness of an Adventure-Based Training Programme in promoting Physical Activity, Reducing Fatigue, & Enhancing Quality of Life among Hong Kong Chinese Childhood Cancer Survivors., The 20th East Asian Forum of Nursing Scholars – Globalization and Research in Doctoral Nursing Education. 2017. |
| JIANG N., Cheng T., Wang M., Chan G.C.F., Jin L., Li H. and Sun H., Tracking iron associated proteomes in pathogens by a fluorescence approach, Metallomics. Royal Society of Chemistry, 2017, 10: 77-82. |
| JIANG N., Cheng T., Wang M., Chan G.C.F., Jin L., Li H. and Sun H., Tracking iron-associated proteomes in pathogens by a fluorescence approach, Metallomics. 2018, 10: 77-82. |
| Kwok J.S.Y., GUO M., Yang W., Ip P., Chan G.C.F., Ho J., Lee C.K., Middleton D. and Lu L., Estimation of optimal donor number in Bone Marrow Donor Registry: Hong Kong’s experience, Human Immunology. Elsevier Inc, 2017. |
| Liu A.P.Y., Ho K.W.F., Chan L.K., Ng J.Y., Lee S.L., Chan G.C.F., Leung T.F. and Ip P., Chinese medical students' knowledge, attitude and practice towards human papillomavirus vaccination and their intention to recommend the vaccine., Journal of Paediatrics and Child Health. 2017. |
| Mak C.Y.K., Cheuk D.K.L., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Liu A.P.Y., Neurological Complications In Chinese Children Undergoing Hematopoietic Stem Cell Transplantation (hsct), ASPR 2017. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Yang L.H., Chik S.C.C., Au K.Y. and Chan G.C.F., Evaluation of anti-inflammatory activity of novel synthesized phenylpropanoid esters, International Journal of Drug Research and Technology. 2018, 8: 1. |
| Researcher : Chan HSS |
| Project Title: | Comprehensive mutation analysis for childhood onset neuromuscular disorder in Chinese patients using Next Generation Sequencing panels |
| Investigator(s): | Chan HSS, Chung BHY, Lee HHC, Wong CNV |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 08/2016 |
| Project Title: | Study of transcription factors and application of CRISPR-Cas9 strategy to target intron 1 splice site mutation of a patient with X-linked dilated cardiomyopathy in restoring the dystrophin level in the cardiac muscle cells |
| Investigator(s): | Chan HSS, Chan GCF, Tan-Un KC |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 10/2017 |
| List of Research Outputs |
| Baertling F., Sánche-Caballero L., van den Brand M.A.M., Fung C.W., Chan H.S.S., Wong C.N.V., Hellebrekers D.M.E., de Coo I.F.M., Smeitink J.A.N. .A.M., Rodnburg R.J.T. and Nijtmans L.G.J., NDUFA9 point mutations cause a variable mitochondrial complex I assembly defect , Clinical Genetics. 2017. |
| Chan H.S.S., Enable living – Challenges and Opportunities in AOMC countries : A Panel Discussion – sharing experience in HKSAR. The 16th Asian and Oceanian Myology Center Annual Scientific Meeting Singapore. 6-8 Aug 2017 , 2017. |
| Chan H.S.S., Neuromuscular Disorder – Diagnosis and Treatment: local challenges and advances, Neuromuscular Disorder Symposium of the 13th Congress of Asian Society for Pediatric Research. Hong Kong. 2017. |
| Chan H.S.S., The Genetic Basis of Spinal Muscular Atrophy. , Neuromuscular and neurometabolic genetics symposium of the 2nd BCM_CUHK- Fudan Joint Symposium in Clinical Genetics cum 14th Asia Pacific Congress in Maternal Fetal Medicine. Hong Kong. 2018. |
| Chan H.S.S., Ho R.S.L., Lo I.F.M., Kan A.M.C. and Lun K.S., X-linked Dilated Cardiomyopathy with Mutation In The 5′ Splice Site Intron 1 Of Dystrophin Gene With Utrophin Upregulation, Journal Of Pediatric Neurology. 2017. |
| Chiu A.T.G., Chan H.S.S., Wu S.P., Ting S.H., Chung B.H.Y., Chan A.O.K. and Wong C.N.V., Spinal Muscular Atrophy With Respiratory Distress Type 1—A Child With Atypical Presentation, Child Neurology Open. 2018, 5: 2329048X1876981. |
| Ho A.C.C., Chan H.S.S., Chan E., Wong S.S.N., Fung S.T.H., Cherk S.W.W., Fung E.L.W., Ma K.H., Tsui K.W., Yau E.K.C. and Wong C.N.V., Anti- N -methyl- d -aspartate receptor encephalitis in children: Incidence and experience in Hong Kong, Brain and Development. 2018, 40: 473-479. |
| Koeks Z., Bladen C.L., Van Zwet E., Pogoryelova O. and Chan H.S.S., Clinical Outcomes in Duchenne Muscular Dystrophy: A Study of 5345 Patients from the TREAT-NMD DMD Global Database., Journal of Neuromuscular Diseases. 2017, 4(4): 293-306. |
| Researcher : Chan KW |
| List of Research Outputs |
| Mao H., Yang W., Latour S., Yang J., Winter S., Zheng J., Ni K., Lv M., Liu C., Huang H., Chan K.W., Lee P.P.W., Tu W., Fischer A. and Lau Y.L., RASGRP1 mutation in autoimmune lymphoproliferative syndrome-like disease, Journal of Allergy and Clinical Immunology. 2017. |
| Researcher : Chan LY |
| List of Research Outputs |
| Chiu S.S.S., Kwan Y.W., Feng S., Wong J.S.C., Leung C.W., Chan L.Y., Chan K.H., Ng T.K., To W.K., Cowling B.J. and Peiris J.S.M., Influenza vaccine effectiveness against influenza A(H3N2) hospitalizations in children in Hong Kong in a prolonged season, 2016/17., J Infect Dis.. Oxford University Press, 2018. |
| Chiu S.S.S., Kwan Y.W., Feng S., Wong J.S.C., Leung C.W., Chan L.Y., Peiris J.S.M. and Cowling B.J., Interim estimate of influenza vaccine effectiveness in hospitalised children, Hong Kong, 2017/18, Eurosurveillance. European Centre for Disease Prevention and Control, 2018, 23. |
| Cowling B.J., Wu P., Lo J.Y.C., Chan K.H., Chan L.Y., Fang J., So L.Y., Peiris J.S.M. and Chiu S.S.S., Population-based pediatric hospitalization burden of lineage-specific influenza B in Hong Kong, 2004–2014, Clinical Infectious Diseases. 2017, 65: 300-307. |
| Researcher : Chan S |
| List of Research Outputs |
| Chan S. and Chan G.C.F., A novel synthetic compound bismuth zinc citrate could potentially reduce cisplatin induced toxicity without compromising the anticancer effect through enhanced expression of metallothionein and GSH , The 13th Congress of Asian Society for Pediatric Research. 2017. |
| Chan S. and Chan G.C.F., Deferiprone Inhibits Iron Overload-Induced Tissue Factor Bearing Endothelial Microparticle Generation by Inhibition Oxidative Stress Induced Mitochondrial Injury, and Apoptosis, HKPS Joint Annual Research & Scientific Meeting . 2017. |
| Chan S., Lian Q., Cheung Y.F. and Chan G.C.F., Deferiprone inhibits iron overload-induced tissue factor bearing endothelial microparticle generation by inhibition oxidative stress induced mitochondrial injury, and apoptosis, Toxicology and Applied Pharmacology . 2018, 338: 148-158. |
| Researcher : Chan SHS |
| Project Title: | Comprehensive mutation analysis for childhood onset neuromuscular disorder in Chinese patients using Next Generation Sequencing panels |
| Investigator(s): | Chan HSS, Chung BHY, Lee HHC, Wong CNV |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 08/2016 |
| Project Title: | Study of transcription factors and application of CRISPR-Cas9 strategy to target intron 1 splice site mutation of a patient with X-linked dilated cardiomyopathy in restoring the dystrophin level in the cardiac muscle cells |
| Investigator(s): | Chan HSS, Chan GCF, Tan-Un KC |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 10/2017 |
| List of Research Outputs |
| Researcher : Chan SY |
| Project Title: | Role of TSPYL2 in epigenetic control of gene expression |
| Investigator(s): | Chan SY, Chan KMJ |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2014 |
| Completion Date: | 08/2017 |
| Project Title: | TSPYL1 and TSPYL4: Novel tumour suppressors? |
| Investigator(s): | Chan SY, Ching YP |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2017 |
| List of Research Outputs |
| Chan S.Y., 26 Feb 2018 Adjudicator, Postgraduate symposium, Department of Pathology, HKU, 2018. |
| Chan S.Y., 9 Jan 2018, Facilitator for Case-based Workshop (Animal Ethics), Research Ethics for Graduate Students , 2018. |
| Chan S.Y., Jan 8 2019, Discussion group facilitator, 2018-19 Research Integrity Workshop on Animal Research Ethics , 2018. |
| Researcher : Chee WYY |
| List of Research Outputs |
| Chee W.Y.Y., Chung H.Y., Wong R.M.S. and Wong K.K.Y., Jaundice in infants and children: causes, diagnosis and management, Hong Kong Medical Journal. 2018, 24: 285-292. |
| Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145. |
| Researcher : Cheong KN |
| List of Research Outputs |
| Leung K.K.Y., Sou Da Rosa Duque J., Yu K.M., Cheong K.N., Chong C.Y., Ho M.H.K. and Chow P.C., Myocardial oedema in an 8-year-old Chinese boy with life-threatening idiopathic systemic capillary leak syndrome requiring extracorporeal membrane oxygenation support, 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies. 2018. |
| Researcher : Cheuk DKL |
| Project Title: | Renal dysfunction in patients with transfusion-dependent thalassaemia (REDEFINE study) |
| Investigator(s): | Cheuk KLD |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 10/2016 |
| List of Research Outputs |
| Researcher : Cheuk KLD |
| Project Title: | Renal dysfunction in patients with transfusion-dependent thalassaemia (REDEFINE study) |
| Investigator(s): | Cheuk KLD |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 10/2016 |
| List of Research Outputs |
| LI W.Y.V., LAI C.T.M., Liu A.P.Y., Cheuk K.L.D. and Cheung Y.F., Left atrial mechanics and integrated calibrated backscatter in anthracycline-treated long-term survivors of childhood cancers. , Ultrasound in Medicine & Biology. 2017, 43: 1897-1905. |
| Researcher : Cheung PT |
| Project Title: | The Endocrine Society 83rd Annual Meeting Mutations of the CYP11B2 Gene in a Patient with Corticosterone Methyl Oxidase Type II Deficiency |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2001 |
| Project Title: | International Perinatal Collegium 2005 Meeting New Approaches in Old Models - Identification of Novel Molecular Alterations in Neonatal Mouse Hypoxic-Ischaemic Brain Damage |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 07/2005 |
| Project Title: | 4th Asian Epigenomics Meeting Methyl mercury induced epigenetic dysregulation of BDNF gene in NG108 cells in vitro – a possible mechanism of environment-epigenome interactions underlying neuropsychiatric and neurodevelopmental disorders. |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 08/2009 |
| Project Title: | 9th Joint Meeting of Paediatric Endocrinology; Effective treatment with low dose dihydrotestosterone gel on three Chinese boys with 5-alpha-reductase II deficiency |
| Investigator(s): | Cheung PT |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2013 |
| List of Research Outputs |
| Li R.H.W., Lam K.S.L., Tam S., Wong E., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction Of Metabolically Unhealthy Phenotype By The Visceral Accumulation Index, Lipid Accumulation Index And Triglyceride-glucose Index In Chinese Women With Polycystic Ovary Syndrome, European Society of Human Reproduction and Embryology Annual Meeting, 2-5 Jul 2017, Geneva, Switzerland. 2017. |
| Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of incident metabolic syndrome and dysglycaemia by adiposity and insulin resistance indices in Chinese women with polycystic ovary syndrome: a 4-year longitudinal study, 100th Annual Meeting & Expo of the Endocrine Society. 2018. |
| Li R.H.W., Lam K.S.L., Tam S., Wong E.W.K., Lee V.C.Y., Cheung P.T., Ho P.C. and Ng E.H.Y., Prediction of metabolically unhealthy phenotype by the visceral adiposity index, lipid accumulation product and triglyceride-glucose index in Chinese women with polycystic ovary syndrome, 33rd Annual Meeting, European Society of Human Reproduction and Embryology. 2017. |
| Man E., Cheung P.T. and Cheung Y.F., Associations between arterial structure and function and serum levels of liver enzymes in obese adolescents., Journal of Paediatrics & Child Health. 2017, 53: 691-697. |
| Researcher : Cheung YF |
| Project Title: | CSX/NKX2.5 mutations in patients with pulmonary atresia and intact ventricular septum |
| Investigator(s): | Cheung YF, Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Project Title: | Development of a multimedia tool for teaching of paediatric cardiology |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Run Run Shaw Research and Teaching Endowment Fund - Teaching Grants |
| Start Date: | 04/2004 |
| Project Title: | Circulating MicroRNAs and Myocardial Damage in Paediatric Cancer Patients Receiving Anthracyline Therapy |
| Investigator(s): | Cheung YF, Cheuk KLD, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2014 |
| Completion Date: | 07/2017 |
| Project Title: | Circulating Transforming Growth Factor-β and Aortic Dilation in Patients with Repaired Congenital Heart Disease |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2015 |
| Project Title: | Right and Left Atrial Function in Patients with Thalassaemia Major: Interaction with Ventricular Diastolic Function and Arterial Mechanics (Project No. 2015/07) |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 11/2015 |
| Project Title: | Multi-modality evaluation of cardiac function in children late after cancer therapy: the emerging field of paediatric cardio-oncology |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Cancer Foundation - General Award |
| Start Date: | 01/2016 |
| Project Title: | Novel MRI T1 mapping for estimation of T1 relaxation time of myocardium in patients with beta-thalassaemia major |
| Investigator(s): | Cheung YF, See WSQ, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 01/2017 |
| Project Title: | Remote Ischaemic Preconditioning in Paediatric Cancer Patients Receiving Anthracyline Therapy |
| Investigator(s): | Cheung YF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2018 |
| List of Research Outputs |
| Chan S., Lian Q., Cheung Y.F. and Chan G.C.F., Deferiprone inhibits iron overload-induced tissue factor bearing endothelial microparticle generation by inhibition oxidative stress induced mitochondrial injury, and apoptosis, Toxicology and Applied Pharmacology . 2018, 338: 148-158. |
| Cheung Y.F., Clinical Applications of Speckle Tracking Echocardiography in Pediatric Heart Diseases , WFUMB 2017, Taipei, 2017. 2017. |
| Cheung Y.F., Echocardiographic Assessment of Fetal Cardiac Function., WFUMB 2017, Taipei, 2017. 2017. |
| Cheung Y.F., How Has Fetal Echocardiography Shaped the Practice of Pediatric Cardiology?, WFUMB 2017, Taipei, 2017.. 2017. |
| Cheung Y.F., Ultrasound Assessment of Right Ventricular Function in Pediatric Heart Disease., WFUMB 2017, Taipei, 2017.. 2017. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chan K.L., Tiwari A.F.Y., Chow C.B., Ho W., Wong W.C.W., Chan M.C.M., Chen E.Y.H., Cheung Y.F. and Ip P., A Sports-based Youth Development Program, Teen Mental Health, And Physical Fitness: An RCT, Pediatrics. 2017, 140. |
| Ip P., Ho K.W.F., Louie L.H.T., Chung T.W.H., Cheung Y.F., Lee S.L., Hui S.S.C., Ho W.K.Y., Ho D.S.Y., Wong W.H.S. and Jiang F., Childhood Obesity and Physical Activity-Friendly School Environments, The Journal of Pediatrics. 2017, 191: 110-116. |
| LAI C.T.M., Ng E.K.O., Chow P.C., Kwong A. and Cheung Y.F., Circulating microRNA in patients with repaired tetralogy of Fallot., European Journal of Clinical Investigation. 2017, 47: 574-582. |
| LI W.Y.V., LAI C.T.M., Liu A.P.Y., Cheuk K.L.D. and Cheung Y.F., Left atrial mechanics and integrated calibrated backscatter in anthracycline-treated long-term survivors of childhood cancers. , Ultrasound in Medicine & Biology. 2017, 43: 1897-1905. |
| Man E., Cheung P.T. and Cheung Y.F., Associations between arterial structure and function and serum levels of liver enzymes in obese adolescents., Journal of Paediatrics & Child Health. 2017, 53: 691-697. |
| To A.H.M., Li V.W.Y., Ng M.Y. and Cheung Y.F., Quantification of Pulmonary Regurgitation by Vector Flow Mapping in Congenital Heart Patients after Repair of Right Ventricular Outflow Obstruction: A Preliminary Study, Journal of the American Society of Echocardiography. 2017. |
| Researcher : Chiang AKS |
| Project Title: | Genetic studies of tubercubosis |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 03/2002 |
| Project Title: | Prospective study of virologic and immunologic parameters of primary Epstein-Barr virus infection in Chinese children |
| Investigator(s): | Chiang AKS, Chan KH |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2003 |
| Project Title: | Prospective study of Epstein-Barr virus (EBV) strains in primary EBV infection |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Project Title: | Longitudinal study of Epstein-Barr virus specific antibody responses in childhood infectious mononucleosis |
| Investigator(s): | Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 12/2005 |
| Project Title: | Delineating pathogenic mutations in Epstein-Barr virus genomes of nasopharyngeal carcinoma using next generation sequencing technology |
| Investigator(s): | Chiang AKS, Lung ML, Sham PC, Yang W, Kwong DLW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2015 |
| Project Title: | Mechanism of cell death by inhibition of histone deacetylation and proteasome degradation pathways in Burkitt lymphoma and lymphoblastoid cells |
| Investigator(s): | Chiang AKS, Hui KF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 04/2017 |
| Project Title: | Reactivation of Epstein-Barr virus (EBV) lytic cycle in EBV-associated epithelial malignancies by iron chelators and evaluation of its therapeutic potential |
| Investigator(s): | Chiang AKS, Hui KF, Yang D |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 05/2017 |
| List of Research Outputs |
| Fung K.F.K., Kan Y.L.E., Liu A.P.Y., Chiang A.K.S. and Khong P.L., Utility of 18F-FDG and 11C-Acetate PET-CT in management of hepatoblastoma patients prior to liver transplantation, AOSPR 2017, Shanghai, China, 20-24 August 2017. |
| Mak C.Y.K., Cheuk D.K.L., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Liu A.P.Y., Neurological Complications In Chinese Children Undergoing Hematopoietic Stem Cell Transplantation (hsct), ASPR 2017. |
| Researcher : Chik SCC |
| List of Research Outputs |
| Yang L.H. and Chik S.C.C., Compounds and Uses Thereof for Treating Inflammation and Modulating Immune Responses., Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang and Stanley C Chik. Taiwanese Patent No: I600426, , 2017. |
| Yang L.H. and Chik S.C.C., Coriolus Versicolor Extracts, Methods of Isolating Biologically-Active Compounds, and Uses Thereof. PI: Allan SY Lau. Co-I: Cindy LH Yang and Stanley C Chik. Owner: HKU Versitech Limited and Purapharm International. Australian Patent No. 2013246612., 2018. |
| Yang L.H. and Chik S.C.C., Coriolus Versicolor Extracts, Methods of Isolating Biologically-Active Compounds, and Uses., Thereof., Type: Provisional. Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang and Stanley C Chik. Owner: HKU Versitech Limited and Purapharm International., 2017. |
| Yang L.H., Chik S.C.C., Law H.Y. and Lee D.C.W., Coriolus Versicolor Extracts, Methods of Preparation and Uses Thereof., Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang, Stanley C Chik, Anna HY Law and Davy CW Lee. Japanese Patent No. 6185093., 2017. |
| Yang L.H., Chik S.C.C., Au K.Y. and Chan G.C.F., Evaluation of anti-inflammatory activity of novel synthesized phenylpropanoid esters, International Journal of Drug Research and Technology. 2018, 8: 1. |
| Researcher : Chiu SSS |
| Project Title: | Streptococcus pneumoniae carriage in young children in Hong Kong |
| Investigator(s): | Chiu SSS, Ho PL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health Services Research Fund - Full Grants |
| Start Date: | 10/1999 |
| Project Title: | Impact of universal vaccination with the 7-valent conjugate pneumocccal vaccine (PCV7) in Hong Kong on the incidence of pneumonia hospitalization and carriage in children |
| Investigator(s): | Chiu SSS, Ho PL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Centre for Health Protection |
| Start Date: | 07/2010 |
| Project Title: | A prospective longitudinal study to correlate maternal antibodies against influenza A and B with influenza infection and hospitalization in the first 6 months of life |
| Investigator(s): | Chiu SSS, Cowling BJ, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2014 |
| Completion Date: | 02/2018 |
| List of Research Outputs |
| Chiu S.S.S., Kwan Y.W., Feng S., Wong J.S.C., Leung C.W., Chan L.Y., Chan K.H., Ng T.K., To W.K., Cowling B.J. and Peiris J.S.M., Influenza vaccine effectiveness against influenza A(H3N2) hospitalizations in children in Hong Kong in a prolonged season, 2016/17., J Infect Dis.. Oxford University Press, 2018. |
| Chiu S.S.S., Kwan Y.W., Feng S., Wong J.S.C., Leung C.W., Chan L.Y., Peiris J.S.M. and Cowling B.J., Interim estimate of influenza vaccine effectiveness in hospitalised children, Hong Kong, 2017/18, Eurosurveillance. European Centre for Disease Prevention and Control, 2018, 23. |
| Cowling B.J. and Chiu S.S.S., Efficacy of inactivated influenza vaccines in young children., The Lancet Child & Adolescent Health. Elsevier, 2018, 2: 307-308. |
| Cowling B.J., Wu P., Lo J.Y.C., Chan K.H., Chan L.Y., Fang J., So L.Y., Peiris J.S.M. and Chiu S.S.S., Population-based pediatric hospitalization burden of lineage-specific influenza B in Hong Kong, 2004–2014, Clinical Infectious Diseases. 2017, 65: 300-307. |
| Researcher : Chiu TA |
| List of Research Outputs |
| Chiu T.A., Pei L.C.S., MAK C.C.Y., Leung K.C., YU H.C., Lee S.L., Vreeburg M., Pfundt R., van der Burgt I., Kleefstra T., Frederic T.M.T., Nambot S., Faivre L., Bruel A.L., Rossi M., Isidor B., Kury S., Cogne B., Besnard T., Willems M., Reijnders M.R.F. and Chung B.H.Y., Okur-Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion, Clinical Genetics. 2018, 93: 880-890. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Researcher : Chong CY |
| List of Research Outputs |
| Chua G.T., Sou Da Rosa Duque J., Chong C.Y., Lee P.P.W., Lau Y.L. and Ho M.H.K., Paediatric case series of drug reaction with eosinophilia and systemic symptoms (dress): 12-year experience at a single referral centre in Hong Kong and the first reported use of infliximab, European Annals Of Allergy And Clinical Immunology. 2018. |
| Leung K.K.Y., Sou Da Rosa Duque J., Yu K.M., Cheong K.N., Chong C.Y., Ho M.H.K. and Chow P.C., Myocardial oedema in an 8-year-old Chinese boy with life-threatening idiopathic systemic capillary leak syndrome requiring extracorporeal membrane oxygenation support, 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies. 2018. |
| Sou Da Rosa Duque J., Chong C.Y., Lau Y.L. and Ho M.H.K., A novel case of systemic delayed-type hypersensitivity to local anesthetics, The 13th Congress of the Asian Society for Pediatric Research. 2017. |
| Researcher : Chow CB |
| Project Title: | Measuring the burden of fatal and nonfatal injury in Hong Kong |
| Investigator(s): | Chow CB, Ip P, McGhee S, Tsui MSH, Kam CW, Chan EWY, Wong WHS, Chiu IWS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 07/2014 |
| Project Title: | Measuring the practicability and effectiveness of online-based injury prevention anticipatory guidance |
| Investigator(s): | Chow CB, Ip P, Wong WHS, Tang MHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health Care and Promotion Scheme - Research Grant Projects |
| Start Date: | 07/2016 |
| Project Title: | Developing indicators to monitor injury trend and burden in Hong Kong |
| Investigator(s): | Chow CB, Ip P, Wong WHS |
| Department: | The University of Hong Kong |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 08/2016 |
| List of Research Outputs |
| Chow C.B., Leung M., Leung G.K.K., Shen W.Y., Kam C.W., Cheung H.M., Auyeung K.L. and Ip P., Epidemiology of paediatric trauma in Hong Kong: a multicenter cohort study, Clinical Epidemiology and Global Health. 2018, Epub on 2018-02-06. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chow C.B., Chan M.C.M. and Ip P., A Sports Program Improves Adolescent Mental Health Through Resilience And Sleep Quality: A Randomized Controlled Trial, 76th Annual Scientific Meeting of American Psychosomatic Society. 2018, 80: A99. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chan K.L., Tiwari A.F.Y., Chow C.B., Ho W., Wong W.C.W., Chan M.C.M., Chen E.Y.H., Cheung Y.F. and Ip P., A Sports-based Youth Development Program, Teen Mental Health, And Physical Fitness: An RCT, Pediatrics. 2017, 140. |
| Ip P., Ho K.W., Rao N., Sun J., Young M.E., Chow C.B., Tso W.Y.W. and Hon K.L., Impact of nutritional supplements on cognitive development of children in developing countries: A meta-analysis, Scientific Reports. 2017. |
| Ip P., Tso W.Y.W., Rao N., Ho K.W.F., Chan K.L., Fu K.W., Li S.L., Goh W., Wong W.H.S. and Chow C.B., Rasch validation of the Chinese parent–child interaction scale (CPCIS), World Journal of Pediatrics. 2018, 14: 238-246. |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Wong R.S.M., Ho K.W.F., Wong W.H.S., TUNG T.S., Chow C.B., Rao N., Chan K.L. and Ip P., Parental Involvement in Primary School Education: its Relationship with Children’s Academic Performance and Psychosocial Competence through Engaging Children with School, Journal of Child and Family Studies. 2018, 27: 1544-1555. |
| Researcher : Chow PC |
| List of Research Outputs |
| LAI C.T.M., Ng E.K.O., Chow P.C., Kwong A. and Cheung Y.F., Circulating microRNA in patients with repaired tetralogy of Fallot., European Journal of Clinical Investigation. 2017, 47: 574-582. |
| Researcher : Chu WY |
| List of Research Outputs |
| Cheng S.W., Luk H.M., Chu W.Y., Tung Y.L., Kwan E.Y.W., Lo I.F.M. and Chung B.H.Y., A report of three families with FBN1- related acromelic dysplasias and review of literature for genotype-phenotype correlation in gelophysic dysplasia, European Journal of Medical Genetics. 2017, 61(4): 219-224. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Researcher : Chua GT |
| List of Research Outputs |
| Chua G.T., Sou Da Rosa Duque J., Chong C.Y., Lee P.P.W., Lau Y.L. and Ho M.H.K., Paediatric case series of drug reaction with eosinophilia and systemic symptoms (dress): 12-year experience at a single referral centre in Hong Kong and the first reported use of infliximab, European Annals Of Allergy And Clinical Immunology. 2018. |
| Researcher : Chung BHY |
| Project Title: | Copy-number variations in Chinese patients with conotruncal defects - a pilot study of 100 patients |
| Investigator(s): | Chung BHY, Liu APY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Heart Foundation - General Award |
| Start Date: | 03/2013 |
| Project Title: | Cell lineage-specific differential DNA methylation in Chinese patients with early-onset systemic lupus erythematosus: implications for disease susceptibility |
| Investigator(s): | Chung BHY, Lau YL, Yang W, Lee PPW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Completion Date: | 01/2018 |
| Project Title: | Identifying the genetic causes underlying prenatally-diagnosed structural congenital anomalies (SCAs) by whole-exome sequencing (WES) |
| Investigator(s): | Chung BHY, Liu APY, Kan SYA, Hui PW, Chan YK, Yang W, Tang MHY, Sham PC |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 07/2015 |
| Completion Date: | 03/2018 |
| Project Title: | Comprehensive Evaluation of Disable Infants and Children with Genetic Disorders |
| Investigator(s): | Chung BHY, Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | The Society for the Relief of Disabled Children |
| Start Date: | 09/2015 |
| Project Title: | Identifying somatic mutations in PIK3CA-Related Overgrowth Spectrum – Implications for targeted therapeutic treatment |
| Investigator(s): | Chung BHY, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2016 |
| Completion Date: | 04/2018 |
| Project Title: | Using Paired-end whole genome sequencing to investigate balanced chromosomal translocation associated with congenital anomalies/neurodevelopmental disorders |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | Phenotypes associated with rare diseases and genetic disorders affecting patients from diverse Asian ethnicity |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | FDNA, Inc. - General Award |
| Start Date: | 07/2017 |
| Project Title: | 38th Annual David W. Smith Workshop on Malformations and Morphogenesis; EXOME SEQUENCINGIN OF 103 PAEDIATRIC PATIENTS IN HONG KONG – IMPORTANCE OF CLINICAL GENETICIST IN THE INTERPRETATION |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 08/2017 |
| Completion Date: | 08/2017 |
| Project Title: | Undiagnosed disease programme |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Medix Medical Services Asia Limited |
| Start Date: | 09/2017 |
| Project Title: | A new candidate gene for human heterotaxy - does it cause ciliopathy and congenital malformation ? |
| Investigator(s): | Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2018 |
| Project Title: | Evaluating the Analytical Validity and Clinical Utility of Whole-Genome Sequencing for Cytogenetically Balanced Chromosomal Abnormalities in Prenatal Diagnosis |
| Investigator(s): | Chung BHY, Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Mini Grant |
| Start Date: | 06/2018 |
| List of Research Outputs |
| Chaudhry A., Chung B.H.Y., Stavropoulos D.J., Araya M.P., Ali A., Heon E. and Chitayat D., Agenesis of the corpus callosum, Developmental delay, Autism spectrum disorders, facial dysmorphism, and Posterior polymorphous corneal dystrophy associated with ZEB1 gene deletion, American Journal of Medical Genetics, Part A. 2017, 173(9): 2467-2471. |
| Cheng S.W., Luk H.M., Chu W.Y., Tung Y.L., Kwan E.Y.W., Lo I.F.M. and Chung B.H.Y., A report of three families with FBN1- related acromelic dysplasias and review of literature for genotype-phenotype correlation in gelophysic dysplasia, European Journal of Medical Genetics. 2017, 61(4): 219-224. |
| Cheung K.W., Lai W.S.C., MAK C.C.Y., Hui P.W., Chung B.H.Y. and Kan S.Y.A., A case of prenatal isolated talipes and 22q11.2 deletion syndrome-an important chromosomal disorder missed by noninvasive prenatal screening, Prenatal Diagnosis. 2018, 38(5): 376-378. |
| Chiu A.T.G., Chan H.S.S., Wu S.P., Ting S.H., Chung B.H.Y., Chan A.O.K. and Wong C.N.V., Spinal Muscular Atrophy With Respiratory Distress Type 1—A Child With Atypical Presentation, Child Neurology Open. 2018, 5: 2329048X1876981. |
| Chiu T.A., Pei L.C.S., MAK C.C.Y., Leung K.C., YU H.C., Lee S.L., Vreeburg M., Pfundt R., van der Burgt I., Kleefstra T., Frederic T.M.T., Nambot S., Faivre L., Bruel A.L., Rossi M., Isidor B., Kury S., Cogne B., Besnard T., Willems M., Reijnders M.R.F. and Chung B.H.Y., Okur-Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion, Clinical Genetics. 2018, 93: 880-890. |
| Chung B.H.Y., YEUNG K.S., Mok T.K.G., Choufani S., Lau Y.L. and Weksberg R., Blood cell type-specific genome-wide DNA methylation analysis of Chinese patients with early-onset systemic lupus erythematosus identifies loss of DNA methylation in genes related to the Type I Interferon pathway, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017. |
| Chung B.H.Y., Diagnosing undiagnosed genetic conditions, Genomic Diagnostic in Current Practice Seminar, Association of Private Medical Specialists of Hong Kong, 11 November 2017. 2017. |
| Chung B.H.Y., Editorial member, American Journal of Medical Genetics. 2017. |
| Chung B.H.Y., Exome sequenxing of 103 paediatric patients in Hong Kong - Importance of clinical geneticist in the interpretation, 38th David Smith Workshop on Malforamtions on Morphogenesis, Stowe, Vermont, USA, 26-29 August 2017. |
| Chung B.H.Y., External Specialist, Advanced Diploma in Nutrition / Advanced Diploma in Child and Adolescent Nutrition Programmes. 2017. |
| Chung B.H.Y., NGS in Prenatal Diagnosis/reproductive Genetics, 12th Asia-Pacific Conference on Human Genetics "Genomic Medicine and Clinical Practice", Bangkok, Thailand, 8-10 November 2017. |
| Chung B.H.Y., Outstanding project entitled "Little People Care Alliance", Faculty Prize Presentation Ceremony 2018, 21 February 2018. 2018. |
| Chung B.H.Y., Paper award the Best Young Investigator Prize 2017, title "Use of clinical chromosomal microarray in Hong Kong Chinese patients with autism spectrum disorder - implications of a copy number variation involving DPP10", Hong Kong College of Paediatricians. 2017. |
| Chung B.H.Y., Reviewer, Nature. 2017. |
| Chung B.H.Y., Role of Epigenetics in Infectious Disease, Hong Kong Paediatric Foundation and Hong Kong Paediatric Society - Summit on the Immuno-surveillance against Childhood Infections in the Chinese Speaking Communities, HK, 5-6 Aug 2017. |
| Chung B.H.Y., Summit Forum of China's Standardized Medical Residency Training, Chinese Medical Doctor Association (CDMA), Beijing, 9-10 September 2017, The Hong Kong Academy of Medicine Newsletter, Autumn 2017. 2017. |
| Chung B.H.Y., Tasforce Member, Strategic Service Framework for Genetic and Genomic Services, COC, Hospital Authority, HK. 2018. |
| Chung B.H.Y., Training of Clinical Geneticists in Asia -- an important strategy to improve the care of families with birth defects, 12th Asia Pacific Conference of Human Genetics, Birth Defects Workshop (APCHG 2017), Bangkok, 8-11 Nov 2017. |
| Chung B.H.Y., Training of Clinical Genetics in Asia -- an important strategy to improve the care of families with birth defects, 12th Asia-Pacific Conference on Human Genetics - Precongress Workshop - Birth Defects, Bangkok, Thailand, 8 November 2017. |
| Gras D., Cousin C., Kappeler C., Fung C.W., Auvin S., Essid N., Chung B.H.Y., Dacosta L., Hainque E., Luton M., Petit V., Vuillaumier S., Tanguy O.B., Flamand-roze E. and Mochel F., A simple blood test expedites the diagnosis of GLUT1 deficiency syndrome, Annals of Neurology. 2017, 82(1): 133-138. |
| Kruszka P., Porras A.R., de Souza D.H., Moresco A., Huckstadt V., Gill A.D., Boyle A.P., Hu T., Addissie Y.A., Mok T.K.G., Tekendo-Ngongang C., Fieggen K., Prijoles E.J., Tanpaiboon P., Honey E., Luk H.M., Lo F.M.I., Thong M.K., Muthukumarasamy P., Jones K.L., Belhassan K., Ouldim K., El Bouchikhi I., Bouguenouch L., Shukla A., Girisha K.M., Sirisena N.D., Dissanayake V.H.W., Paththinige C.S., Mishra R., Kisling M.S., Ferreira C.R., de Herreros M.B., Lee N.C., Jamuar S.S., Lai A., Tan E.S., Lim Y.J., Cham Breana W.M., Gupta N., Lotz-Esquivel S., Badilla-Porras R., Hussen D.F., El Ruby M.O., Ashaat E.A., Patil S.J., Dowsett L., Eaton A., Innes A.M., Shotelersuk V., Badoe E., Wonkam A., Obregon M.G., Chung B.H.Y., Trubnykova M., La Serna J., Gallardo Jugo B.E., Ghavez Pastor M., Abarca Barriga H.H., Megarbane A., Kozel B.A., van Haelst M.M., Stevenson R.E., Summar M., Adeyemo A.A., Morris C.A., Moretti-Ferreira D., Linguraru M.G. and Muenke M., Cover Image, Volume 176A, Number 5, May 2018, American Journal of Medical Genetics Part A. 2018, 176. |
| Kruszka P., Porras A.R., Addissie Y.A., Moresco A., Medrano S., Mok T.K.G., LEUNG K.C., Tekendo-Ngongang C., Uwineza A., Thong M.K., Muthukumarasamy P., Honey E., Ekure E.N., Sokunbi O.J., Kalu N., Jones K.L., Kaplan J.D., Abdul-Rahman O.A., Vincent L.M., Love A., Belhassan K., Ouldim K., El Bouchikhi I., Shukla A., Girisha K.M., Patil S.J., Sirsena N.D., Dissanayake V.H.W., Paththinige C.S., Mishra R., Klein-Zighelboim E., Gallardo Jugo B.E., Chavez P M., Abarca-Barriga H.H., Skinner S.A., Prijoles E.J., Badoe E., Gill A.D., Shotelersuk V., Smpokou P., Kisling M.S., Ferreira C.R., Mutesa L., Megabane A., Kline A.D., Kimball A., Okello E., Lwabi P., Aliku T., Tenywa E., Boonchooduang N., Tanpaiboon P., Richieri-Costa A., Wonkam A., Chung B.H.Y., Stevenson R.E., Summar M., Mandal K., Phadke S.R., Obregon M.G., Linguraru M.G. and Muenke M., Noonan syndrome in diverse populations, American Journal of Medical Genetics Part A. 2017, 173(9): 2323-2334. |
| Kruszka P., Porras A.R., de Souza D.H., Moresco A., Huckstadt V., Gill A.D., Goyle A.P., Hu T., Addissie Y.A., Mok T.K.G., Tekendo-Ngongang C., Fieggen K., Prijoles E.J., Tanpaiboon P., Honey E., Luk H.M., Lo F.M.I., Thong M.K., Muthukumarasamy P., Jones K.L., Belhassan K., Ouldim K., El Bouchikhi I., Bouguenouch L., Shukla A., Girisha K.M., Sirisena N.D., Dissanayake V.H.W., Paththinige C.S., Mirshra R., Kislling M.S., Ferreira C.R., de Herreros M.B., Lee N.C., Jamuar S.S., Lai A., Tan E.S., Lim J.Y., Cham Breaba W.M., Gupta N., Lotz-Esquivel S., Badilla-Porras R., Hussen D.F., El Ruby M.O., Ashaat E.A., Patil S.J., Dowsett L., Eaton A., Innes A.M., Shotelersuk V., Badoe E., Wonkam A., Obregon M.G., Chung B.H.Y., Trubnykova M., La Serna J., Gallardo Jugo B.E., Chavez Pastor M., Abarca Barriga H.H., Megarbane A., Kozel B.A., van Haelst M.M., Stevenson R.E., Summar M., Adeyemo A.A., Morris C.A., Moretti-Ferreira D., Linguraru M.G. and Muenke M., Williams-Beuren syndrome in diverse populations, American Journal of Medical Genetics Part A. 2018, 176: 1128-1136. |
| Kwok S.Y., Liu A.P.Y., Chan C.Y.Y., Lun K.S., Fung L.F., MAK C.C.Y., Chung B.H.Y. and Yung T.C., Clinical and Genetic Profile of Congenital Long QT Syndrome in Hong Kong - 18-year Experience in Paediatrics, 26th Annual Scientific Meeting of Hong Kong College of Cardiology, Best Paper Award, June 2018. |
| LEUNG K.C., Kan S.Y.A. and Chung B.H.Y., Next Generation Sequencing in Prenatal Diagnosis, 12th Asia-Pacific Conference on Human Genetics "Genomic Medicine and Clinical Practice", Bangkok, Thailand, 8-10 November 2017. |
| LEUNG K.C., Kan S.Y.A. and Chung B.H.Y., Next generation sequencing in prenatal diagnosis, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017. |
| Michel M.E., Konczyk D.J., Yeung K.S., Murillo R., Vivero M.P., Hall A.M., Zurakowski D., Adams D., Gupta A., Huang A.Y., Chung B.H.Y. and Warman M.L., Causal somatic mutations in urine DNA from persons with the CLOVES subgroup of the PIK3CA Related Overgrowth Spectrum, Clinical Genetics. 2017, 93(5): 1075-1080. |
| Poon W.Y.S., Tao Q.V., Kan S.Y.A. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis, Hong Kong Journal of Paediatrics (new series). 2018, 23(1): 141. |
| So P.L., Cheng Y.K.Y., Cheuk K.Y., Chiu W.K., Mak S.L., Mok S.L., Lo T.K., Yung W.K., Lo F.M., Chung B.H.Y., Kan S.Y.A., Lee C.P. and Tang M.H.Y., Parental decisions following prenatal diagnosis of sex chromosome aneuploidy in Hong Kong, The Journal of Obstetrics and Gynaecology Research. 2017, 43(12): 1821-1829. |
| Tsai A., Wang W., Chung B.H.Y. and Li H., 臨床遺傳專科醫生認証規范, Chinese Journal of Medical Genetics, special issue. 2017. |
| Tsai A., Chung B.H.Y., Li H. and Dai H., 臨床遺傳培訓基地規范, Chinese Journal of Medical Genetics, special issues. 2017. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Yu K.P.T., Luk H.M., Gordon C.T., Fung G., Oufadem M., Garcia-Barcelo M.M., Amiel J., Chung B.H.Y., Lo F.M.I. and Tan T.Y., Mandibulofacial dysostosis Guion-Almeida type caused by novel EFTUD2 splice site variants in two Asian children, Clinical Dysmorphology. 2018, 27: 31-35. |
| Researcher : Fung CW |
| Project Title: | Neurogenetic Project |
| Investigator(s): | Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | The Society for the Relief of Disabled Children |
| Start Date: | 05/2016 |
| Project Title: | Pilot Programme for Diagnosis and Management of Mitochondrial Diseases |
| Investigator(s): | Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | The Society for the Relief of Disabled Children |
| Start Date: | 05/2016 |
| Project Title: | Territory-wide Mitochondrial Disease Registry in Hong Kong (Phase I) and Territory-wide Inborn Errors of Metabolism Registry in Hong Kong (Phase II) |
| Investigator(s): | Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | The Joshua Hellmann Foundation for Orphan Disease |
| Start Date: | 06/2017 |
| List of Research Outputs |
| Gras D., Cousin C., Kappeler C., Fung C.W., Auvin S., Essid N., Chung B.H.Y., Dacosta L., Hainque E., Luton M., Petit V., Vuillaumier S., Tanguy O.B., Flamand-roze E. and Mochel F., A simple blood test expedites the diagnosis of GLUT1 deficiency syndrome, Annals of Neurology. 2017, 82(1): 133-138. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Researcher : Fung LF |
| List of Research Outputs |
| Kwok S.Y., Liu A.P.Y., Chan C.Y.Y., Lun K.S., Fung L.F., MAK C.C.Y., Chung B.H.Y. and Yung T.C., Clinical and Genetic Profile of Congenital Long QT Syndrome in Hong Kong - 18-year Experience in Paediatrics, 26th Annual Scientific Meeting of Hong Kong College of Cardiology, Best Paper Award, June 2018. |
| Researcher : GUO M |
| List of Research Outputs |
| Chan Y.P., Wong M.W.K., Tang L.W.M., GUO M., Yang W., Ip P., Li P.K.T., Leung C.B., Chau K.F., Lam J.C.K., Yeung N.K.M. and Kwok J.S.Y., A simplified method of calculating cPRA for kidney allocation application in Hong Kong: a retrospective study., Transplant International . Wiley, 2017. |
| Kwok J.S.Y., GUO M., Yang W., Ip P., Chan G.C.F., Ho J., Lee C.K., Middleton D. and Lu L., Estimation of optimal donor number in Bone Marrow Donor Registry: Hong Kong’s experience, Human Immunology. Elsevier Inc, 2017. |
| Researcher : HUANG C |
| List of Research Outputs |
| HUANG C., Zeng Y. and Tu W., The role of γδ-T cells during human pregnancy, American Journal of Reproductive Immunology. 2017, 78: e12713. |
| Researcher : Ho KW |
| Project Title: | Glasgow/HKU Early Career Mobility Funds 2018-19 |
| Investigator(s): | Ho KWF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Glasgow/HKU Early Career Mobility Fund |
| Start Date: | 06/2018 |
| List of Research Outputs |
| Ip P., Ho K.W., Rao N., Sun J., Young M.E., Chow C.B., Tso W.Y.W. and Hon K.L., Impact of nutritional supplements on cognitive development of children in developing countries: A meta-analysis, Scientific Reports. 2017. |
| Researcher : Ho KWF |
| Project Title: | Glasgow/HKU Early Career Mobility Funds 2018-19 |
| Investigator(s): | Ho KWF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Glasgow/HKU Early Career Mobility Fund |
| Start Date: | 06/2018 |
| List of Research Outputs |
| Chan K.L., Lo K.M.C., Ho K.W.F., Zhu S., Lai S.M.K. and Ip P., The Longer-Term Psychosocial Development of Adolescents: Child Development Accounts and the Role of Mentoring, Frontiers in Pediatrics. 2018, 6. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chow C.B., Chan M.C.M. and Ip P., A Sports Program Improves Adolescent Mental Health Through Resilience And Sleep Quality: A Randomized Controlled Trial, 76th Annual Scientific Meeting of American Psychosomatic Society. 2018, 80: A99. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chan K.L., Tiwari A.F.Y., Chow C.B., Ho W., Wong W.C.W., Chan M.C.M., Chen E.Y.H., Cheung Y.F. and Ip P., A Sports-based Youth Development Program, Teen Mental Health, And Physical Fitness: An RCT, Pediatrics. 2017, 140. |
| Ho K.W.F., Colloquium Scholar Award, American Psychosomatic Society. 2018. |
| Ho W.K.Y., Ahmed M.D., Leong C.I., Chan P., Van Niekerk R.L., Huang F., Tian H., Liu M., Chan N., Silva J., Wong W.H.S., Ho K.W.F. and Ip P., Body Mass Index (BMI) assessment among Macau students: age group differences and weight management strategies, Anthropological Review. 2017, 80: 349-367. |
| Ip P., Ho K.W.F., Louie L.H.T., Chung T.W.H., Cheung Y.F., Lee S.L., Hui S.S.C., Ho W.K.Y., Ho D.S.Y., Wong W.H.S. and Jiang F., Childhood Obesity and Physical Activity-Friendly School Environments, The Journal of Pediatrics. 2017, 191: 110-116. |
| Ip P., Tso W.Y.W., Rao N., Ho K.W.F., Chan K.L., Fu K.W., Li S.L., Goh W., Wong W.H.S. and Chow C.B., Rasch validation of the Chinese parent–child interaction scale (CPCIS), World Journal of Pediatrics. 2018, 14: 238-246. |
| Liu A.P.Y., Ho K.W.F., Chan L.K., Ng J.Y., Lee S.L., Chan G.C.F., Leung T.F. and Ip P., Chinese medical students' knowledge, attitude and practice towards human papillomavirus vaccination and their intention to recommend the vaccine., Journal of Paediatrics and Child Health. 2017. |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Wong R.S.M., Ho K.W.F., Wong W.H.S., TUNG T.S., Chow C.B., Rao N., Chan K.L. and Ip P., Parental Involvement in Primary School Education: its Relationship with Children’s Academic Performance and Psychosocial Competence through Engaging Children with School, Journal of Child and Family Studies. 2018, 27: 1544-1555. |
| Zhang Y., Zhang D., Li X., Ip P., Ho K.W.F., Jiang Y., Sun Y., Zhu Q., Zhu W., Zhang J., Zhao H., Wang G., Shen X. and Jiang F., Daily Time-Use Patterns and Obesity and Mental Health among Primary School Students in Shanghai: A Population-Based Cross-Sectional Study, Scientific Reports. 2017, 7. |
| Researcher : Ho MHK |
| List of Research Outputs |
| Chan A.W.M., Hon K.L., Leung T.F., Ho M.H.K., Sou Da Rosa Duque J. and Lee T.H., The effects of global warming on allergic diseases, Hong Kong Medical Journal. 2018, 24(3): 277-284. |
| Chua G.T., Sou Da Rosa Duque J., Chong C.Y., Lee P.P.W., Lau Y.L. and Ho M.H.K., Paediatric case series of drug reaction with eosinophilia and systemic symptoms (dress): 12-year experience at a single referral centre in Hong Kong and the first reported use of infliximab, European Annals Of Allergy And Clinical Immunology. 2018. |
| Lee T.H., Wu Y.Y., Chan J.K.C., Ho M.H.K., Li P.H. and Sou Da Rosa Duque J., Immunoglobulin G testing in the diagnosis of food allergy and intolerance, Hong Kong Medical Journal. 2017, 23(4): 419-420. |
| Lee T.H., Leung T.F., Wong G., Ho M.H.K., Sou Da Rosa Duque J., Li P.H., Lam W.F., Wu A., Chan E., Lai C. and Lau Y.L., The unmet provision of allergy services in Hong Kong impairs capability for allergy prevention – implications for the Asia Pacific region, Asian Pacific Journal of Allergy and Immunology. 2017. |
| Leung K.K.Y., Sou Da Rosa Duque J., Yu K.M., Cheong K.N., Chong C.Y., Ho M.H.K. and Chow P.C., Myocardial oedema in an 8-year-old Chinese boy with life-threatening idiopathic systemic capillary leak syndrome requiring extracorporeal membrane oxygenation support, 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies. 2018. |
| Sou Da Rosa Duque J., Chong C.Y., Lau Y.L. and Ho M.H.K., A novel case of systemic delayed-type hypersensitivity to local anesthetics, The 13th Congress of the Asian Society for Pediatric Research. 2017. |
| Researcher : Ho SP |
| Project Title: | Understanding the molecular pathogenesis of osteosarcoma |
| Investigator(s): | Ho SP, Chan D, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 06/2016 |
| Researcher : Hui KF |
| Project Title: | Effects on induction of viral lytic cycle in Epstein-Barr virus-associated epithelial malignancies by combining histone deacetylase inhibitor and a novel organic compound |
| Investigator(s): | Hui KF, Chiang AKS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 06/2018 |
| Researcher : Ip P |
| Project Title: | Promoting alcohol-related attitudinal and behavioural change amongst adolescents through Internet intervention: A cluster randomised controlled trial |
| Investigator(s): | Ip P, Chow CB, Lam TH, Ho DSY, Wong WHS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 07/2015 |
| Project Title: | Attention-deficit/hyperactivity disorder and child maltreatment: A population-based study |
| Investigator(s): | Ip P, Chan EKL, Fong DYT, Sham PC |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2016 |
| Completion Date: | 12/2017 |
| Project Title: | Does methylphenidate treatment increase seizure risk in children and adolescents with Attention Deficit Hyperactivity Disorder? |
| Investigator(s): | Ip P, Fong DYT, Man KCK, Sham PC, Chan EWY, Wong ICK |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 08/2017 |
| Project Title: | Early Childhood Intervention to Reduce Deficits of Underprivileged Children |
| Investigator(s): | Ip P, Rao N, Chan MCM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | The Hong Kong Jockey Club Charities Trust - General Award |
| Start Date: | 08/2017 |
| List of Research Outputs |
| Chan K.L., Lo K.M.C., Ho K.W.F., Zhu S., Lai S.M.K. and Ip P., The Longer-Term Psychosocial Development of Adolescents: Child Development Accounts and the Role of Mentoring, Frontiers in Pediatrics. 2018, 6. |
| Chan Y.P., Wong M.W.K., Tang L.W.M., GUO M., Yang W., Ip P., Li P.K.T., Leung C.B., Chau K.F., Lam J.C.K., Yeung N.K.M. and Kwok J.S.Y., A simplified method of calculating cPRA for kidney allocation application in Hong Kong: a retrospective study., Transplant International . Wiley, 2017. |
| Chen Q., LO K.M.C., Zhu Y.H., Cheung A.S.Y., Chan K.L. and Ip P., Family Poly-victimization and Cyberbullying among Adolescents in a Chinese School Sample, Child Abuse & Neglect. UK, Elvsevier, 2018, 77: 180-187. |
| Chow C.B., Leung M., Leung G.K.K., Shen W.Y., Kam C.W., Cheung H.M., Auyeung K.L. and Ip P., Epidemiology of paediatric trauma in Hong Kong: a multicenter cohort study, Clinical Epidemiology and Global Health. 2018, Epub on 2018-02-06. |
| Guo Y., Yu Y.T.E., WONG R.S.M., Ip P., Tiwari A.F.Y., Wong C.K.H., Fung S.C.C., Wong W.H.S. and Lam C.L.K., Maternal mental quality of life mediates the associations between intimate partner abuse against mothers and their children’s behaviours and quality of life in low-income Chinese families, Quality of Life Research. 2017, 26 (12): 3297-3306. |
| Guo Y., Wong C.K.H., WONG R.S.M., Yu Y.T.E., Ip P. and Lam C.L.K., Spillover Effects of Maternal Chronic Disease on Children’s Quality of Life and Behaviors Among Low-Income Families, The Patient - Patient-Centered Outcomes Research. 2018. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chow C.B., Chan M.C.M. and Ip P., A Sports Program Improves Adolescent Mental Health Through Resilience And Sleep Quality: A Randomized Controlled Trial, 76th Annual Scientific Meeting of American Psychosomatic Society. 2018, 80: A99. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chan K.L., Tiwari A.F.Y., Chow C.B., Ho W., Wong W.C.W., Chan M.C.M., Chen E.Y.H., Cheung Y.F. and Ip P., A Sports-based Youth Development Program, Teen Mental Health, And Physical Fitness: An RCT, Pediatrics. 2017, 140. |
| Ho W.K.Y., Ahmed M.D., Leong C.I., Chan P., Van Niekerk R.L., Huang F., Tian H., Liu M., Chan N., Silva J., Wong W.H.S., Ho K.W.F. and Ip P., Body Mass Index (BMI) assessment among Macau students: age group differences and weight management strategies, Anthropological Review. 2017, 80: 349-367. |
| Ip P., Ho K.W.F., Louie L.H.T., Chung T.W.H., Cheung Y.F., Lee S.L., Hui S.S.C., Ho W.K.Y., Ho D.S.Y., Wong W.H.S. and Jiang F., Childhood Obesity and Physical Activity-Friendly School Environments, The Journal of Pediatrics. 2017, 191: 110-116. |
| Ip P., Ho K.W., Rao N., Sun J., Young M.E., Chow C.B., Tso W.Y.W. and Hon K.L., Impact of nutritional supplements on cognitive development of children in developing countries: A meta-analysis, Scientific Reports. 2017. |
| Ip P., Tso W.Y.W., Rao N., Ho K.W.F., Chan K.L., Fu K.W., Li S.L., Goh W., Wong W.H.S. and Chow C.B., Rasch validation of the Chinese parent–child interaction scale (CPCIS), World Journal of Pediatrics. 2018, 14: 238-246. |
| Kwok J.S.Y., GUO M., Yang W., Ip P., Chan G.C.F., Ho J., Lee C.K., Middleton D. and Lu L., Estimation of optimal donor number in Bone Marrow Donor Registry: Hong Kong’s experience, Human Immunology. Elsevier Inc, 2017. |
| Liu A.P.Y., Ho K.W.F., Chan L.K., Ng J.Y., Lee S.L., Chan G.C.F., Leung T.F. and Ip P., Chinese medical students' knowledge, attitude and practice towards human papillomavirus vaccination and their intention to recommend the vaccine., Journal of Paediatrics and Child Health. 2017. |
| Man K.C.K., Coghill D., Chan E.W., LAU C.Y., Hollis C., Liddle E., Banaschewski T., McCarthy S., Neubert A., Sayal K., Ip P., Schuemie M.J., Sturkenboom M.C.J.M., Sonuga-Barke E., Buitelaar J., Carucci S., Zuddas A., Kovshoff H., Garas P., Nagy P., Inglis S.K., Konrad K., Häge A., Rosenthal E. and Wong I.C.K., Association of Risk of Suicide Attempts With Methylphenidate Treatment, JAMA Psychiatry. 2017, 74: 1048–1055. |
| Man K.C.K., Ip P., Chan E.W., Law S.L., Leung M.T.Y., Ma E.X.Y., Quek W.T. and Wong I.C.K., Effectiveness of Pharmacological Treatment for Attention-Deficit/Hyperactivity Disorder on Physical Injuries: A Systematic Review and Meta-Analysis of Observational Studies, CNS Drugs. 2017, 31: 1043-1055. |
| Man K.C.K., Chan E.W., Ip P., Coghill D., Simonoff E., Chan P.K.L., Lau W.C.Y., Schuemie M.J., Sturkenboom M.C.J.M. and Wong I.C.K., Prenatal antidepressant exposure and the risk of attention-deficit hyperactivity disorder in children: A systematic review and meta-analysis, Neuroscience & Biobehavioral Reviews. 2018, 86: 1-11. |
| Rao N., Sun J., Richards B.D., Weber A., Sincovich A., Darmstadt G. .L. and Ip P., Assessing Diversity in Early Childhood Development in the East Asia-Pacific, Child Indicators Research. 2018. |
| Rao N., Becher Y., Lee P.L.D., Sun J., Richards B.D., Bacon-Shone J., Ip P., Umayahara M. and Chen E., Assessing early development and learning: the East Asia-Pacific Early Childhood Development Scales (EAP-ECDS). EAP-ECDS Brief, ARNEC. UNICEF. OSF.. 2017. |
| WONG R.S.M., Yu Y.T.E., Guo Y., Wan Y.F., Chin W.Y., Wong C.K.H., Fung S.C.C., Tung T.S., Wong W.H.S., Ip P., Tiwari A.F.Y. and Lam C.L.K., A prospective cohort study to investigate parental stress and child health in low-income Chinese families: protocol paper, BMJ Open. 2018, 8: e018792. |
| Wong C.K.H., Man K.C.K., Ip P., Kwan Y.W. and McGhee S., Mothers’ Preferences and Willingness to Pay for Human Papillomavirus Vaccination for Their Daughters: A Discrete Choice Experiment in Hong Kong, Value in Health. 2017, 21 (5): 622-629. |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Wong R.S.M., Ho K.W.F., Wong W.H.S., TUNG T.S., Chow C.B., Rao N., Chan K.L. and Ip P., Parental Involvement in Primary School Education: its Relationship with Children’s Academic Performance and Psychosocial Competence through Engaging Children with School, Journal of Child and Family Studies. 2018, 27: 1544-1555. |
| Zhang Y., Zhang D., Li X., Ip P., Ho K.W.F., Jiang Y., Sun Y., Zhu Q., Zhu W., Zhang J., Zhao H., Wang G., Shen X. and Jiang F., Daily Time-Use Patterns and Obesity and Mental Health among Primary School Students in Shanghai: A Population-Based Cross-Sectional Study, Scientific Reports. 2017, 7. |
| Researcher : Jalal K |
| List of Research Outputs |
| Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145. |
| Researcher : Kwan EYW |
| List of Research Outputs |
| Cheng S.W., Luk H.M., Chu W.Y., Tung Y.L., Kwan E.Y.W., Lo I.F.M. and Chung B.H.Y., A report of three families with FBN1- related acromelic dysplasias and review of literature for genotype-phenotype correlation in gelophysic dysplasia, European Journal of Medical Genetics. 2017, 61(4): 219-224. |
| Researcher : Kwan YW |
| List of Research Outputs |
| Chiu S.S.S., Kwan Y.W., Feng S., Wong J.S.C., Leung C.W., Chan L.Y., Chan K.H., Ng T.K., To W.K., Cowling B.J. and Peiris J.S.M., Influenza vaccine effectiveness against influenza A(H3N2) hospitalizations in children in Hong Kong in a prolonged season, 2016/17., J Infect Dis.. Oxford University Press, 2018. |
| Chiu S.S.S., Kwan Y.W., Feng S., Wong J.S.C., Leung C.W., Chan L.Y., Peiris J.S.M. and Cowling B.J., Interim estimate of influenza vaccine effectiveness in hospitalised children, Hong Kong, 2017/18, Eurosurveillance. European Centre for Disease Prevention and Control, 2018, 23. |
| Wong C.K.H., Man K.C.K., Ip P., Kwan Y.W. and McGhee S., Mothers’ Preferences and Willingness to Pay for Human Papillomavirus Vaccination for Their Daughters: A Discrete Choice Experiment in Hong Kong, Value in Health. 2017, 21 (5): 622-629. |
| Researcher : Kwok SY |
| List of Research Outputs |
| Kwok S.Y., Liu A.P.Y., Chan C.Y.Y., Lun K.S., Fung L.F., MAK C.C.Y., Chung B.H.Y. and Yung T.C., Clinical and Genetic Profile of Congenital Long QT Syndrome in Hong Kong - 18-year Experience in Paediatrics, 26th Annual Scientific Meeting of Hong Kong College of Cardiology, Best Paper Award, June 2018. |
| Researcher : Kwong KY |
| Project Title: | 8th World Congress on Targeting Mitochondria; DRAVET SYNDROME AND MITOCHONDRIAL DYSFUNCTION |
| Investigator(s): | Kwong KY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2017 |
| Completion Date: | 10/2017 |
| Researcher : LAI CTM |
| List of Research Outputs |
| LAI C.T.M., Ng E.K.O., Chow P.C., Kwong A. and Cheung Y.F., Circulating microRNA in patients with repaired tetralogy of Fallot., European Journal of Clinical Investigation. 2017, 47: 574-582. |
| LI W.Y.V., LAI C.T.M., Liu A.P.Y., Cheuk K.L.D. and Cheung Y.F., Left atrial mechanics and integrated calibrated backscatter in anthracycline-treated long-term survivors of childhood cancers. , Ultrasound in Medicine & Biology. 2017, 43: 1897-1905. |
| Researcher : LEUNG KC |
| List of Research Outputs |
| Chiu T.A., Pei L.C.S., MAK C.C.Y., Leung K.C., YU H.C., Lee S.L., Vreeburg M., Pfundt R., van der Burgt I., Kleefstra T., Frederic T.M.T., Nambot S., Faivre L., Bruel A.L., Rossi M., Isidor B., Kury S., Cogne B., Besnard T., Willems M., Reijnders M.R.F. and Chung B.H.Y., Okur-Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion, Clinical Genetics. 2018, 93: 880-890. |
| Kruszka P., Porras A.R., Addissie Y.A., Moresco A., Medrano S., Mok T.K.G., LEUNG K.C., Tekendo-Ngongang C., Uwineza A., Thong M.K., Muthukumarasamy P., Honey E., Ekure E.N., Sokunbi O.J., Kalu N., Jones K.L., Kaplan J.D., Abdul-Rahman O.A., Vincent L.M., Love A., Belhassan K., Ouldim K., El Bouchikhi I., Shukla A., Girisha K.M., Patil S.J., Sirsena N.D., Dissanayake V.H.W., Paththinige C.S., Mishra R., Klein-Zighelboim E., Gallardo Jugo B.E., Chavez P M., Abarca-Barriga H.H., Skinner S.A., Prijoles E.J., Badoe E., Gill A.D., Shotelersuk V., Smpokou P., Kisling M.S., Ferreira C.R., Mutesa L., Megabane A., Kline A.D., Kimball A., Okello E., Lwabi P., Aliku T., Tenywa E., Boonchooduang N., Tanpaiboon P., Richieri-Costa A., Wonkam A., Chung B.H.Y., Stevenson R.E., Summar M., Mandal K., Phadke S.R., Obregon M.G., Linguraru M.G. and Muenke M., Noonan syndrome in diverse populations, American Journal of Medical Genetics Part A. 2017, 173(9): 2323-2334. |
| LEUNG K.C., Kan S.Y.A. and Chung B.H.Y., Next Generation Sequencing in Prenatal Diagnosis, 12th Asia-Pacific Conference on Human Genetics "Genomic Medicine and Clinical Practice", Bangkok, Thailand, 8-10 November 2017. |
| LEUNG K.C., Kan S.Y.A. and Chung B.H.Y., Next generation sequencing in prenatal diagnosis, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : LI WYV |
| List of Research Outputs |
| LI W.Y.V., LAI C.T.M., Liu A.P.Y., Cheuk K.L.D. and Cheung Y.F., Left atrial mechanics and integrated calibrated backscatter in anthracycline-treated long-term survivors of childhood cancers. , Ultrasound in Medicine & Biology. 2017, 43: 1897-1905. |
| Researcher : LU A |
| List of Research Outputs |
| CHEN Q., WEN K., LU A., LIU M., NI K., XIANG Z., Liu Y. and Tu W., Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody, Frontiers in Immunology. 2018, 9. |
| Researcher : Lam KT |
| List of Research Outputs |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Researcher : Lam LNA |
| List of Research Outputs |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Researcher : Lau ASY |
| Project Title: | Cytokines, Signaling & Diseases 2003 The Role of Protein Kinase PKR in the Induction of Cytokine Expression by Bacillus Calmette Guerin Through NF-kappaB |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2003 |
| Project Title: | Cytokine Dysregulation and Virus-Induced Cell Death in Avian Influenza Virus Infections |
| Investigator(s): | Lau ASY, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2005 |
| Project Title: | Factors affecting mycobacteria evasion of immunity: effects of HIV on cellular signaling and kinases |
| Investigator(s): | Lau ASY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 09/2009 |
| Researcher : Lau YL |
| Project Title: | A community-based educational program on thalassaemias to enhance awareness with the aim to reduce burden of thalassaemia related health problems in Hong Kong |
| Investigator(s): | Lau YL, Ha SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health Promotion Projects |
| Start Date: | 09/1997 |
| Project Title: | Comparison of process upgrade varicella vaccine (Puvv) with VARILRIX-TM |
| Investigator(s): | Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/1999 |
| Project Title: | p21 gene polymorphism with systemic lupus erythematosus and rheumatoid arthritis |
| Investigator(s): | Lau YL, Lau WCS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 09/2005 |
| Project Title: | Association of cytokine and chemokine genes polymorphism with susceptibility to SARS and severity of SARS |
| Investigator(s): | Lau YL, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 09/2005 |
| Project Title: | The effects of BTK mutation on TLR3-mediated type I IFN response against poliovirus infection in X-linked agammaglobulinemia |
| Investigator(s): | Lau YL, Tu W, Lee PPW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2014 |
| Completion Date: | 01/2018 |
| List of Research Outputs |
| Chua G.T., Sou Da Rosa Duque J., Chong C.Y., Lee P.P.W., Lau Y.L. and Ho M.H.K., Paediatric case series of drug reaction with eosinophilia and systemic symptoms (dress): 12-year experience at a single referral centre in Hong Kong and the first reported use of infliximab, European Annals Of Allergy And Clinical Immunology. 2018. |
| Chung B.H.Y., YEUNG K.S., Mok T.K.G., Choufani S., Lau Y.L. and Weksberg R., Blood cell type-specific genome-wide DNA methylation analysis of Chinese patients with early-onset systemic lupus erythematosus identifies loss of DNA methylation in genes related to the Type I Interferon pathway, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017. |
| Lee T.H., Leung T.F., Wong G., Ho M.H.K., Sou Da Rosa Duque J., Li P.H., Lam W.F., Wu A., Chan E., Lai C. and Lau Y.L., The unmet provision of allergy services in Hong Kong impairs capability for allergy prevention – implications for the Asia Pacific region, Asian Pacific Journal of Allergy and Immunology. 2017. |
| Luk D.W., Tu W. and Lau Y.L., Family History of Early Infant Death Correlates with Earlier Age at Diagnosis But Not Shorter Time to Diagnosis for Severe Combined Immunodeficiency, Frontiers in Immunology. 2017, 8. |
| Mao H., Yang W., Latour S., Yang J., Winter S., Zheng J., Ni K., Lv M., Liu C., Huang H., Chan K.W., Lee P.P.W., Tu W., Fischer A. and Lau Y.L., RASGRP1 mutation in autoimmune lymphoproliferative syndrome-like disease, Journal of Allergy and Clinical Immunology. 2017. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Sou Da Rosa Duque J., Chong C.Y., Lau Y.L. and Ho M.H.K., A novel case of systemic delayed-type hypersensitivity to local anesthetics, The 13th Congress of the Asian Society for Pediatric Research. 2017. |
| Researcher : Law HY |
| List of Research Outputs |
| Yang L.H., Chik S.C.C., Law H.Y. and Lee D.C.W., Coriolus Versicolor Extracts, Methods of Preparation and Uses Thereof., Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang, Stanley C Chik, Anna HY Law and Davy CW Lee. Japanese Patent No. 6185093., 2017. |
| Yang L.H. and Law H.Y., Materials and methods for prevention and treatment of viral infections. PI: Allan SY Lau. Co-I: Cindy LH Yang and Anna HY Law., 2018. |
| Yang L.H., Or C.T., Li C.B. and Law H.Y., Novel therapeutic methods for treating inflammation and modulating immune responses, PI: Allan SY Lau. Co-I: Cindy LH Yang and Terry CT Or, James CB Li and Anna HY Law. Owner: HKU Versitech Limited and Bagi Research Limited. European Patent No: 2866638., 2017. |
| Researcher : Lee DCW |
| List of Research Outputs |
| Yang L.H., Chik S.C.C., Law H.Y. and Lee D.C.W., Coriolus Versicolor Extracts, Methods of Preparation and Uses Thereof., Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang, Stanley C Chik, Anna HY Law and Davy CW Lee. Japanese Patent No. 6185093., 2017. |
| Researcher : Lee PPW |
| Project Title: | The role of NLRP3 inflammasome in the induction of protective Th1 and Th17 immune response towards Penicillium marneffei |
| Investigator(s): | Lee PPW, Lau YL, Woo PCY, Tu W, Chan JFW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Completion Date: | 12/2017 |
| List of Research Outputs |
| Chua G.T., Sou Da Rosa Duque J., Chong C.Y., Lee P.P.W., Lau Y.L. and Ho M.H.K., Paediatric case series of drug reaction with eosinophilia and systemic symptoms (dress): 12-year experience at a single referral centre in Hong Kong and the first reported use of infliximab, European Annals Of Allergy And Clinical Immunology. 2018. |
| Mak C.Y.K., Cheuk D.K.L., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Liu A.P.Y., Neurological Complications In Chinese Children Undergoing Hematopoietic Stem Cell Transplantation (hsct), ASPR 2017. |
| Mao H., Yang W., Latour S., Yang J., Winter S., Zheng J., Ni K., Lv M., Liu C., Huang H., Chan K.W., Lee P.P.W., Tu W., Fischer A. and Lau Y.L., RASGRP1 mutation in autoimmune lymphoproliferative syndrome-like disease, Journal of Allergy and Clinical Immunology. 2017. |
| Researcher : Lee SL |
| Project Title: | Where for Rare |
| Investigator(s): | Lee SL, Chung BHY, Chau SKC, Cheung YF, Tao QV, Tso WYW, Yung AWY, Wong RMS, Lee DCW, Wong WHS |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | The Society for the Relief of Disabled Children |
| Start Date: | 01/2017 |
| List of Research Outputs |
| Chiu T.A., Pei L.C.S., MAK C.C.Y., Leung K.C., YU H.C., Lee S.L., Vreeburg M., Pfundt R., van der Burgt I., Kleefstra T., Frederic T.M.T., Nambot S., Faivre L., Bruel A.L., Rossi M., Isidor B., Kury S., Cogne B., Besnard T., Willems M., Reijnders M.R.F. and Chung B.H.Y., Okur-Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion, Clinical Genetics. 2018, 93: 880-890. |
| Hui L.L., Kwok M.K., Nelson E.A.S., Lee S.L., Leung G.M. and Schooling C.M., The association of breastfeeding with insulin resistance at 17 years: Prospective observations from Hong Kong's “Children of 1997” birth cohort, Maternal & Child Nutrition. 2018, 14: e12490. |
| Ip P., Ho K.W.F., Louie L.H.T., Chung T.W.H., Cheung Y.F., Lee S.L., Hui S.S.C., Ho W.K.Y., Ho D.S.Y., Wong W.H.S. and Jiang F., Childhood Obesity and Physical Activity-Friendly School Environments, The Journal of Pediatrics. 2017, 191: 110-116. |
| Liu A.P.Y., Ho K.W.F., Chan L.K., Ng J.Y., Lee S.L., Chan G.C.F., Leung T.F. and Ip P., Chinese medical students' knowledge, attitude and practice towards human papillomavirus vaccination and their intention to recommend the vaccine., Journal of Paediatrics and Child Health. 2017. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : Leung CW |
| List of Research Outputs |
| Chiu S.S.S., Kwan Y.W., Feng S., Wong J.S.C., Leung C.W., Chan L.Y., Chan K.H., Ng T.K., To W.K., Cowling B.J. and Peiris J.S.M., Influenza vaccine effectiveness against influenza A(H3N2) hospitalizations in children in Hong Kong in a prolonged season, 2016/17., J Infect Dis.. Oxford University Press, 2018. |
| Chiu S.S.S., Kwan Y.W., Feng S., Wong J.S.C., Leung C.W., Chan L.Y., Peiris J.S.M. and Cowling B.J., Interim estimate of influenza vaccine effectiveness in hospitalised children, Hong Kong, 2017/18, Eurosurveillance. European Centre for Disease Prevention and Control, 2018, 23. |
| Researcher : Leung KC |
| List of Research Outputs |
| Chiu T.A., Pei L.C.S., MAK C.C.Y., Leung K.C., YU H.C., Lee S.L., Vreeburg M., Pfundt R., van der Burgt I., Kleefstra T., Frederic T.M.T., Nambot S., Faivre L., Bruel A.L., Rossi M., Isidor B., Kury S., Cogne B., Besnard T., Willems M., Reijnders M.R.F. and Chung B.H.Y., Okur-Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion, Clinical Genetics. 2018, 93: 880-890. |
| Kruszka P., Porras A.R., Addissie Y.A., Moresco A., Medrano S., Mok T.K.G., LEUNG K.C., Tekendo-Ngongang C., Uwineza A., Thong M.K., Muthukumarasamy P., Honey E., Ekure E.N., Sokunbi O.J., Kalu N., Jones K.L., Kaplan J.D., Abdul-Rahman O.A., Vincent L.M., Love A., Belhassan K., Ouldim K., El Bouchikhi I., Shukla A., Girisha K.M., Patil S.J., Sirsena N.D., Dissanayake V.H.W., Paththinige C.S., Mishra R., Klein-Zighelboim E., Gallardo Jugo B.E., Chavez P M., Abarca-Barriga H.H., Skinner S.A., Prijoles E.J., Badoe E., Gill A.D., Shotelersuk V., Smpokou P., Kisling M.S., Ferreira C.R., Mutesa L., Megabane A., Kline A.D., Kimball A., Okello E., Lwabi P., Aliku T., Tenywa E., Boonchooduang N., Tanpaiboon P., Richieri-Costa A., Wonkam A., Chung B.H.Y., Stevenson R.E., Summar M., Mandal K., Phadke S.R., Obregon M.G., Linguraru M.G. and Muenke M., Noonan syndrome in diverse populations, American Journal of Medical Genetics Part A. 2017, 173(9): 2323-2334. |
| LEUNG K.C., Kan S.Y.A. and Chung B.H.Y., Next Generation Sequencing in Prenatal Diagnosis, 12th Asia-Pacific Conference on Human Genetics "Genomic Medicine and Clinical Practice", Bangkok, Thailand, 8-10 November 2017. |
| LEUNG K.C., Kan S.Y.A. and Chung B.H.Y., Next generation sequencing in prenatal diagnosis, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : Leung KKY |
| List of Research Outputs |
| Leung K.K.Y., Sou Da Rosa Duque J., Yu K.M., Cheong K.N., Chong C.Y., Ho M.H.K. and Chow P.C., Myocardial oedema in an 8-year-old Chinese boy with life-threatening idiopathic systemic capillary leak syndrome requiring extracorporeal membrane oxygenation support, 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies. 2018. |
| Researcher : Leung NHT |
| List of Research Outputs |
| Ip K.I., Hon K.L., Tsang Y.C. and Leung N.H.T., Steroid phobia, Chinese medicine and asthma control, In: Chen Wang and Paul Jones, The Clinical Respiratory Journal. 2017. |
| Researcher : Leung TNH |
| List of Research Outputs |
| Hon K.L., Leung A.K.C., Leung T.N.H. and Lee V.W.Y., Complementary, Alternative and Integrative Medicine for Childhood Atopic Dermatitis, Recent Patents on Inflammation & Allergy Drug Discovery. 2017, 11. |
| Leung T.N.H. and Ip K.I., A case of difficult asthma, Hong Kong Society of Paediatric Respirology and Allergy Clinical Meeting. 2017. |
| Leung T.N.H., Acute Respiratory Distress in Children: Evaluation and Management, CNE talk on paediatric resuscitation, Gleneagles Hong Kong Hospital. 2017. |
| Leung T.N.H., Co-morbidities of Allergic rhinitis in Children, Hong Kong Doctor's Union Symposium. 2017. |
| Leung T.N.H., Non-surgical management of Paediatric Obstructive Sleep Apnea, The Hong Kong University Shenzhen Hospital 5th Anniversary Paediatric Forum. 2017. |
| Leung T.N.H. and Hon K.L., Pneumococcus serotypes in pre and post 13-valent polysaccharide conjugate vaccine era: Epidemiology in a pediatric intensive care unit over 10 years, Asia Pacific Association of Paediatric Allergy, Respirology and Immunology (APAPARI) Congress 2017. |
| Researcher : Li CB |
| Project Title: | The role of c-Myc in anti-mycobaterial responses: from bacterial killing to T cell activation |
| Investigator(s): | Li CB, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 02/2014 |
| Project Title: | A role for interleukin-17A in influenza virus induced immune responses and viral replication |
| Investigator(s): | Li CB |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2016 |
| List of Research Outputs |
| Li C.B., Associate Editor, Frontiers in Pharmacology. 2017. |
| Researcher : Liu APY |
| Project Title: | Copy-number variations in Chinese patients with conotruncal defects |
| Investigator(s): | Liu APY, Wong WL, Chung BHY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2013 |
| Project Title: | Immunogenicity and immunomodulatory activitiy of induced pluripotent stem cells-derived cardiomyocytes from human mesenchymal stem cells |
| Investigator(s): | Liu APY, Poon NYE, Boheler KR, Chan GCF |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 06/2014 |
| List of Research Outputs |
| Fung K.F.K., Kan Y.L.E., Liu A.P.Y., Chiang A.K.S. and Khong P.L., Utility of 18F-FDG and 11C-Acetate PET-CT in management of hepatoblastoma patients prior to liver transplantation, AOSPR 2017, Shanghai, China, 20-24 August 2017. |
| Kwok S.Y., Liu A.P.Y., Chan C.Y.Y., Lun K.S., Fung L.F., MAK C.C.Y., Chung B.H.Y. and Yung T.C., Clinical and Genetic Profile of Congenital Long QT Syndrome in Hong Kong - 18-year Experience in Paediatrics, 26th Annual Scientific Meeting of Hong Kong College of Cardiology, Best Paper Award, June 2018. |
| LI W.Y.V., LAI C.T.M., Liu A.P.Y., Cheuk K.L.D. and Cheung Y.F., Left atrial mechanics and integrated calibrated backscatter in anthracycline-treated long-term survivors of childhood cancers. , Ultrasound in Medicine & Biology. 2017, 43: 1897-1905. |
| Liu A.P.Y., Ho K.W.F., Chan L.K., Ng J.Y., Lee S.L., Chan G.C.F., Leung T.F. and Ip P., Chinese medical students' knowledge, attitude and practice towards human papillomavirus vaccination and their intention to recommend the vaccine., Journal of Paediatrics and Child Health. 2017. |
| Liu A.P.Y., Orr B., Lin T.O.N.G., Bouffet E., Gururangan S., Crawford J., Kellie S.J., Chintagumpala M., Fisher M., Bowers D.C., Hassall T., Ellison D., Robinson G. and Gajjar A., EMBR-13. FAVORABLE OUTCOMES IN CHILDREN WITH PINEOBLASTOMA TREATED WITH RISK-ADAPTED CRANIOSPINAL IRRADIATION AND CHEMOTHERAPY: RESULTS AND MOLECULAR ANALYSIS FROM THE SJYC07 AND SJMB03 TRIALS, ISPNO 2018. |
| Liu A.P.Y., Orr B., Lin T., Hassall T., Bowers D.C., Bouffet E., Gururangan S., Fisher P., Crawford J., Kellie S.J., Chintagumpala M., Fisher M., Bendel A., Ellison D., Robinson G. and Gajjar A., EMBR-14. RECLASSIFICATION OF CENTRAL NERVOUS SYSTEM PRIMITIVE NEUROECTODERMAL TUMOR (CNS-PNET) INTO ENTITIES REFLECTS OUTCOME: RESULTS FROM THE PROSPECTIVE SJYC07 AND SJMB03 TRIALS, ISPNO 2018. |
| Liu A.P.Y., Harreld J., Jacola L., Gero M., Acharya S., Chiang J., Ghazwani Y., Wu S., Klimo Jr. P., Gajjar A. and Qaddoumi I., LGG-21. LONG-TERM OUTCOME OF PATIENTS WITH PEDIATRIC TECTAL GLIOMA, ISPNO 2018. |
| Liu A.P.Y., Hastings C., Wu S., Bass J.K., Heitzer A., Ashford J., Vestal R., Hoehn M., Chiang J., Ghazwani Y., Acharya S., Conklin H., Boop F., Gajjar A. and Qaddoumi I., LGG-22. TREATMENT OUTCOME AND LONG-TERM HEALTH DEFICITS OF PATIENTS WITH LOW-GRADE GLIOMA DIAGNOSED DURING THE FIRST YEAR OF LIFE, ISPNO 2018. |
| Mak C.Y.K., Cheuk D.K.L., Lee P.P.W., Chiang A.K.S., Ha S.Y., Chan G.C.F. and Liu A.P.Y., Neurological Complications In Chinese Children Undergoing Hematopoietic Stem Cell Transplantation (hsct), ASPR 2017. |
| Researcher : Liu Y |
| List of Research Outputs |
| CHEN Q., WEN K., LU A., LIU M., NI K., XIANG Z., Liu Y. and Tu W., Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody, Frontiers in Immunology. 2018, 9. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Researcher : Lo FMI |
| List of Research Outputs |
| Kruszka P., Porras A.R., de Souza D.H., Moresco A., Huckstadt V., Gill A.D., Boyle A.P., Hu T., Addissie Y.A., Mok T.K.G., Tekendo-Ngongang C., Fieggen K., Prijoles E.J., Tanpaiboon P., Honey E., Luk H.M., Lo F.M.I., Thong M.K., Muthukumarasamy P., Jones K.L., Belhassan K., Ouldim K., El Bouchikhi I., Bouguenouch L., Shukla A., Girisha K.M., Sirisena N.D., Dissanayake V.H.W., Paththinige C.S., Mishra R., Kisling M.S., Ferreira C.R., de Herreros M.B., Lee N.C., Jamuar S.S., Lai A., Tan E.S., Lim Y.J., Cham Breana W.M., Gupta N., Lotz-Esquivel S., Badilla-Porras R., Hussen D.F., El Ruby M.O., Ashaat E.A., Patil S.J., Dowsett L., Eaton A., Innes A.M., Shotelersuk V., Badoe E., Wonkam A., Obregon M.G., Chung B.H.Y., Trubnykova M., La Serna J., Gallardo Jugo B.E., Ghavez Pastor M., Abarca Barriga H.H., Megarbane A., Kozel B.A., van Haelst M.M., Stevenson R.E., Summar M., Adeyemo A.A., Morris C.A., Moretti-Ferreira D., Linguraru M.G. and Muenke M., Cover Image, Volume 176A, Number 5, May 2018, American Journal of Medical Genetics Part A. 2018, 176. |
| Kruszka P., Porras A.R., de Souza D.H., Moresco A., Huckstadt V., Gill A.D., Goyle A.P., Hu T., Addissie Y.A., Mok T.K.G., Tekendo-Ngongang C., Fieggen K., Prijoles E.J., Tanpaiboon P., Honey E., Luk H.M., Lo F.M.I., Thong M.K., Muthukumarasamy P., Jones K.L., Belhassan K., Ouldim K., El Bouchikhi I., Bouguenouch L., Shukla A., Girisha K.M., Sirisena N.D., Dissanayake V.H.W., Paththinige C.S., Mirshra R., Kislling M.S., Ferreira C.R., de Herreros M.B., Lee N.C., Jamuar S.S., Lai A., Tan E.S., Lim J.Y., Cham Breaba W.M., Gupta N., Lotz-Esquivel S., Badilla-Porras R., Hussen D.F., El Ruby M.O., Ashaat E.A., Patil S.J., Dowsett L., Eaton A., Innes A.M., Shotelersuk V., Badoe E., Wonkam A., Obregon M.G., Chung B.H.Y., Trubnykova M., La Serna J., Gallardo Jugo B.E., Chavez Pastor M., Abarca Barriga H.H., Megarbane A., Kozel B.A., van Haelst M.M., Stevenson R.E., Summar M., Adeyemo A.A., Morris C.A., Moretti-Ferreira D., Linguraru M.G. and Muenke M., Williams-Beuren syndrome in diverse populations, American Journal of Medical Genetics Part A. 2018, 176: 1128-1136. |
| Yu K.P.T., Luk H.M., Gordon C.T., Fung G., Oufadem M., Garcia-Barcelo M.M., Amiel J., Chung B.H.Y., Lo F.M.I. and Tan T.Y., Mandibulofacial dysostosis Guion-Almeida type caused by novel EFTUD2 splice site variants in two Asian children, Clinical Dysmorphology. 2018, 27: 31-35. |
| Researcher : Lo KMC |
| List of Research Outputs |
| Chan K.L., Lo K.M.C., Ho K.W.F., Zhu S., Lai S.M.K. and Ip P., The Longer-Term Psychosocial Development of Adolescents: Child Development Accounts and the Role of Mentoring, Frontiers in Pediatrics. 2018, 6. |
| Researcher : Low LCK |
| Project Title: | 12th Asia Pacific Congress of Paediatrics and 2nd Asia Pacific Congress of Paediatric Nursing The Role of Nutritional Intake and Total Energy Expenditure on Early Growth of Babies Born with Intrauterine Growth Retardation |
| Investigator(s): | Low CKL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 09/2006 |
| Researcher : Luk HM |
| List of Research Outputs |
| Kruszka P., Porras A.R., de Souza D.H., Moresco A., Huckstadt V., Gill A.D., Boyle A.P., Hu T., Addissie Y.A., Mok T.K.G., Tekendo-Ngongang C., Fieggen K., Prijoles E.J., Tanpaiboon P., Honey E., Luk H.M., Lo F.M.I., Thong M.K., Muthukumarasamy P., Jones K.L., Belhassan K., Ouldim K., El Bouchikhi I., Bouguenouch L., Shukla A., Girisha K.M., Sirisena N.D., Dissanayake V.H.W., Paththinige C.S., Mishra R., Kisling M.S., Ferreira C.R., de Herreros M.B., Lee N.C., Jamuar S.S., Lai A., Tan E.S., Lim Y.J., Cham Breana W.M., Gupta N., Lotz-Esquivel S., Badilla-Porras R., Hussen D.F., El Ruby M.O., Ashaat E.A., Patil S.J., Dowsett L., Eaton A., Innes A.M., Shotelersuk V., Badoe E., Wonkam A., Obregon M.G., Chung B.H.Y., Trubnykova M., La Serna J., Gallardo Jugo B.E., Ghavez Pastor M., Abarca Barriga H.H., Megarbane A., Kozel B.A., van Haelst M.M., Stevenson R.E., Summar M., Adeyemo A.A., Morris C.A., Moretti-Ferreira D., Linguraru M.G. and Muenke M., Cover Image, Volume 176A, Number 5, May 2018, American Journal of Medical Genetics Part A. 2018, 176. |
| Kruszka P., Porras A.R., de Souza D.H., Moresco A., Huckstadt V., Gill A.D., Goyle A.P., Hu T., Addissie Y.A., Mok T.K.G., Tekendo-Ngongang C., Fieggen K., Prijoles E.J., Tanpaiboon P., Honey E., Luk H.M., Lo F.M.I., Thong M.K., Muthukumarasamy P., Jones K.L., Belhassan K., Ouldim K., El Bouchikhi I., Bouguenouch L., Shukla A., Girisha K.M., Sirisena N.D., Dissanayake V.H.W., Paththinige C.S., Mirshra R., Kislling M.S., Ferreira C.R., de Herreros M.B., Lee N.C., Jamuar S.S., Lai A., Tan E.S., Lim J.Y., Cham Breaba W.M., Gupta N., Lotz-Esquivel S., Badilla-Porras R., Hussen D.F., El Ruby M.O., Ashaat E.A., Patil S.J., Dowsett L., Eaton A., Innes A.M., Shotelersuk V., Badoe E., Wonkam A., Obregon M.G., Chung B.H.Y., Trubnykova M., La Serna J., Gallardo Jugo B.E., Chavez Pastor M., Abarca Barriga H.H., Megarbane A., Kozel B.A., van Haelst M.M., Stevenson R.E., Summar M., Adeyemo A.A., Morris C.A., Moretti-Ferreira D., Linguraru M.G. and Muenke M., Williams-Beuren syndrome in diverse populations, American Journal of Medical Genetics Part A. 2018, 176: 1128-1136. |
| Yu K.P.T., Luk H.M., Gordon C.T., Fung G., Oufadem M., Garcia-Barcelo M.M., Amiel J., Chung B.H.Y., Lo F.M.I. and Tan T.Y., Mandibulofacial dysostosis Guion-Almeida type caused by novel EFTUD2 splice site variants in two Asian children, Clinical Dysmorphology. 2018, 27: 31-35. |
| Researcher : Lun KS |
| List of Research Outputs |
| Kwok S.Y., Liu A.P.Y., Chan C.Y.Y., Lun K.S., Fung L.F., MAK C.C.Y., Chung B.H.Y. and Yung T.C., Clinical and Genetic Profile of Congenital Long QT Syndrome in Hong Kong - 18-year Experience in Paediatrics, 26th Annual Scientific Meeting of Hong Kong College of Cardiology, Best Paper Award, June 2018. |
| Researcher : MAK CCY |
| List of Research Outputs |
| Cheung K.W., Lai W.S.C., MAK C.C.Y., Hui P.W., Chung B.H.Y. and Kan S.Y.A., A case of prenatal isolated talipes and 22q11.2 deletion syndrome-an important chromosomal disorder missed by noninvasive prenatal screening, Prenatal Diagnosis. 2018, 38(5): 376-378. |
| Chiu T.A., Pei L.C.S., MAK C.C.Y., Leung K.C., YU H.C., Lee S.L., Vreeburg M., Pfundt R., van der Burgt I., Kleefstra T., Frederic T.M.T., Nambot S., Faivre L., Bruel A.L., Rossi M., Isidor B., Kury S., Cogne B., Besnard T., Willems M., Reijnders M.R.F. and Chung B.H.Y., Okur-Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion, Clinical Genetics. 2018, 93: 880-890. |
| Kwok S.Y., Liu A.P.Y., Chan C.Y.Y., Lun K.S., Fung L.F., MAK C.C.Y., Chung B.H.Y. and Yung T.C., Clinical and Genetic Profile of Congenital Long QT Syndrome in Hong Kong - 18-year Experience in Paediatrics, 26th Annual Scientific Meeting of Hong Kong College of Cardiology, Best Paper Award, June 2018. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : Man E |
| List of Research Outputs |
| Man E., Cheung P.T. and Cheung Y.F., Associations between arterial structure and function and serum levels of liver enzymes in obese adolescents., Journal of Paediatrics & Child Health. 2017, 53: 691-697. |
| Researcher : Man KCK |
| List of Research Outputs |
| Wong C.K.H., Man K.C.K., Ip P., Kwan Y.W. and McGhee S., Mothers’ Preferences and Willingness to Pay for Human Papillomavirus Vaccination for Their Daughters: A Discrete Choice Experiment in Hong Kong, Value in Health. 2017, 21 (5): 622-629. |
| Researcher : Mok TKG |
| List of Research Outputs |
| Chung B.H.Y., YEUNG K.S., Mok T.K.G., Choufani S., Lau Y.L. and Weksberg R., Blood cell type-specific genome-wide DNA methylation analysis of Chinese patients with early-onset systemic lupus erythematosus identifies loss of DNA methylation in genes related to the Type I Interferon pathway, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017. |
| Kruszka P., Porras A.R., de Souza D.H., Moresco A., Huckstadt V., Gill A.D., Boyle A.P., Hu T., Addissie Y.A., Mok T.K.G., Tekendo-Ngongang C., Fieggen K., Prijoles E.J., Tanpaiboon P., Honey E., Luk H.M., Lo F.M.I., Thong M.K., Muthukumarasamy P., Jones K.L., Belhassan K., Ouldim K., El Bouchikhi I., Bouguenouch L., Shukla A., Girisha K.M., Sirisena N.D., Dissanayake V.H.W., Paththinige C.S., Mishra R., Kisling M.S., Ferreira C.R., de Herreros M.B., Lee N.C., Jamuar S.S., Lai A., Tan E.S., Lim Y.J., Cham Breana W.M., Gupta N., Lotz-Esquivel S., Badilla-Porras R., Hussen D.F., El Ruby M.O., Ashaat E.A., Patil S.J., Dowsett L., Eaton A., Innes A.M., Shotelersuk V., Badoe E., Wonkam A., Obregon M.G., Chung B.H.Y., Trubnykova M., La Serna J., Gallardo Jugo B.E., Ghavez Pastor M., Abarca Barriga H.H., Megarbane A., Kozel B.A., van Haelst M.M., Stevenson R.E., Summar M., Adeyemo A.A., Morris C.A., Moretti-Ferreira D., Linguraru M.G. and Muenke M., Cover Image, Volume 176A, Number 5, May 2018, American Journal of Medical Genetics Part A. 2018, 176. |
| Kruszka P., Porras A.R., Addissie Y.A., Moresco A., Medrano S., Mok T.K.G., LEUNG K.C., Tekendo-Ngongang C., Uwineza A., Thong M.K., Muthukumarasamy P., Honey E., Ekure E.N., Sokunbi O.J., Kalu N., Jones K.L., Kaplan J.D., Abdul-Rahman O.A., Vincent L.M., Love A., Belhassan K., Ouldim K., El Bouchikhi I., Shukla A., Girisha K.M., Patil S.J., Sirsena N.D., Dissanayake V.H.W., Paththinige C.S., Mishra R., Klein-Zighelboim E., Gallardo Jugo B.E., Chavez P M., Abarca-Barriga H.H., Skinner S.A., Prijoles E.J., Badoe E., Gill A.D., Shotelersuk V., Smpokou P., Kisling M.S., Ferreira C.R., Mutesa L., Megabane A., Kline A.D., Kimball A., Okello E., Lwabi P., Aliku T., Tenywa E., Boonchooduang N., Tanpaiboon P., Richieri-Costa A., Wonkam A., Chung B.H.Y., Stevenson R.E., Summar M., Mandal K., Phadke S.R., Obregon M.G., Linguraru M.G. and Muenke M., Noonan syndrome in diverse populations, American Journal of Medical Genetics Part A. 2017, 173(9): 2323-2334. |
| Kruszka P., Porras A.R., de Souza D.H., Moresco A., Huckstadt V., Gill A.D., Goyle A.P., Hu T., Addissie Y.A., Mok T.K.G., Tekendo-Ngongang C., Fieggen K., Prijoles E.J., Tanpaiboon P., Honey E., Luk H.M., Lo F.M.I., Thong M.K., Muthukumarasamy P., Jones K.L., Belhassan K., Ouldim K., El Bouchikhi I., Bouguenouch L., Shukla A., Girisha K.M., Sirisena N.D., Dissanayake V.H.W., Paththinige C.S., Mirshra R., Kislling M.S., Ferreira C.R., de Herreros M.B., Lee N.C., Jamuar S.S., Lai A., Tan E.S., Lim J.Y., Cham Breaba W.M., Gupta N., Lotz-Esquivel S., Badilla-Porras R., Hussen D.F., El Ruby M.O., Ashaat E.A., Patil S.J., Dowsett L., Eaton A., Innes A.M., Shotelersuk V., Badoe E., Wonkam A., Obregon M.G., Chung B.H.Y., Trubnykova M., La Serna J., Gallardo Jugo B.E., Chavez Pastor M., Abarca Barriga H.H., Megarbane A., Kozel B.A., van Haelst M.M., Stevenson R.E., Summar M., Adeyemo A.A., Morris C.A., Moretti-Ferreira D., Linguraru M.G. and Muenke M., Williams-Beuren syndrome in diverse populations, American Journal of Medical Genetics Part A. 2018, 176: 1128-1136. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Researcher : NI K |
| List of Research Outputs |
| CHEN Q., WEN K., LU A., LIU M., NI K., XIANG Z., Liu Y. and Tu W., Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody, Frontiers in Immunology. 2018, 9. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Researcher : Or CT |
| List of Research Outputs |
| Yang L.H., Or C.T., Li C.B. and Law H.Y., Novel therapeutic methods for treating inflammation and modulating immune responses, PI: Allan SY Lau. Co-I: Cindy LH Yang and Terry CT Or, James CB Li and Anna HY Law. Owner: HKU Versitech Limited and Bagi Research Limited. European Patent No: 2866638., 2017. |
| Researcher : Pei LCS |
| List of Research Outputs |
| Chiu T.A., Pei L.C.S., MAK C.C.Y., Leung K.C., YU H.C., Lee S.L., Vreeburg M., Pfundt R., van der Burgt I., Kleefstra T., Frederic T.M.T., Nambot S., Faivre L., Bruel A.L., Rossi M., Isidor B., Kury S., Cogne B., Besnard T., Willems M., Reijnders M.R.F. and Chung B.H.Y., Okur-Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion, Clinical Genetics. 2018, 93: 880-890. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : Poon NYE |
| Project Title: | The effect of miR-200c on the electrophysiological maturation of human embryonic stem cell derived cardiomyocytes |
| Investigator(s): | Poon NYE, Boheler KR, Li RA |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 03/2014 |
| Project Title: | Identification of the optimal source of human mesenchymal stromal cells for the treatment of acute graft-versus-host disease under a clinical-grade ex-vivo culture system |
| Investigator(s): | Poon NYE, Chan GCF, Boheler KR |
| Department: | School of Biomedical Sciences |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 08/2016 |
| List of Research Outputs |
| Lu J., Boheler K.R., Jiang L., Chan C., Tse W., Keung W.W.Y., Poon N.Y.E., Li R.A. and Yao X., Polycystin-2 Plays an Essential Role in Glucose Starvation-Induced Autophagy in Human Embryonic Stem Cell-Derived Cardiomyocytes, STEM CELLS. 2018, 36: 501-513. |
| Researcher : Poon WYS |
| List of Research Outputs |
| Poon W.Y.S., Tao Q.V., Kan S.Y.A. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis, Hong Kong Journal of Paediatrics (new series). 2018, 23(1): 141. |
| Researcher : So HK |
| List of Research Outputs |
| Lam T.H., Ho D.S.Y., So H.K. and NCD Risk Factor Collaboration (NCD-RisC) , Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants, International Journal of Epidemiology. 2018, 47(3): 872-83i. |
| Luo X.X., Zhu Y.S., Sun Y.Q., Ge Q.R., Su J., So H.K., Yam M.C. and Fang F., Does Masked Hypertension Cause Early Left Ventricular Impairment in Youth?, Frontiers in Pediatrics. 2018, 6. |
| Researcher : So KW |
| List of Research Outputs |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Researcher : So LY |
| List of Research Outputs |
| Cowling B.J., Wu P., Lo J.Y.C., Chan K.H., Chan L.Y., Fang J., So L.Y., Peiris J.S.M. and Chiu S.S.S., Population-based pediatric hospitalization burden of lineage-specific influenza B in Hong Kong, 2004–2014, Clinical Infectious Diseases. 2017, 65: 300-307. |
| Researcher : Sou Da Rosa Duque J |
| List of Research Outputs |
| Au Y.L.E., Sou Da Rosa Duque J., Lau W.C.S. and Chan Y.T.E., A patient with anaphylaxis to diphenhydramine without cross-reactivity to loratadine, The Journal of Allergy and Clinical Immunology: In Practice. 2018, 6: 1061-1063. |
| Chan A.W.M., Hon K.L., Leung T.F., Ho M.H.K., Sou Da Rosa Duque J. and Lee T.H., The effects of global warming on allergic diseases, Hong Kong Medical Journal. 2018, 24(3): 277-284. |
| Chua G.T., Sou Da Rosa Duque J., Chong C.Y., Lee P.P.W., Lau Y.L. and Ho M.H.K., Paediatric case series of drug reaction with eosinophilia and systemic symptoms (dress): 12-year experience at a single referral centre in Hong Kong and the first reported use of infliximab, European Annals Of Allergy And Clinical Immunology. 2018. |
| Lee T.H., Wu Y.Y., Chan J.K.C., Ho M.H.K., Li P.H. and Sou Da Rosa Duque J., Immunoglobulin G testing in the diagnosis of food allergy and intolerance, Hong Kong Medical Journal. 2017, 23(4): 419-420. |
| Lee T.H., Leung T.F., Wong G., Ho M.H.K., Sou Da Rosa Duque J., Li P.H., Lam W.F., Wu A., Chan E., Lai C. and Lau Y.L., The unmet provision of allergy services in Hong Kong impairs capability for allergy prevention – implications for the Asia Pacific region, Asian Pacific Journal of Allergy and Immunology. 2017. |
| Leung K.K.Y., Sou Da Rosa Duque J., Yu K.M., Cheong K.N., Chong C.Y., Ho M.H.K. and Chow P.C., Myocardial oedema in an 8-year-old Chinese boy with life-threatening idiopathic systemic capillary leak syndrome requiring extracorporeal membrane oxygenation support, 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies. 2018. |
| Sou Da Rosa Duque J., Chong C.Y., Lau Y.L. and Ho M.H.K., A novel case of systemic delayed-type hypersensitivity to local anesthetics, The 13th Congress of the Asian Society for Pediatric Research. 2017. |
| Researcher : TSANG HY |
| List of Research Outputs |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : TUNG TS |
| List of Research Outputs |
| WONG R.S.M., Yu Y.T.E., Guo Y., Wan Y.F., Chin W.Y., Wong C.K.H., Fung S.C.C., Tung T.S., Wong W.H.S., Ip P., Tiwari A.F.Y. and Lam C.L.K., A prospective cohort study to investigate parental stress and child health in low-income Chinese families: protocol paper, BMJ Open. 2018, 8: e018792. |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Wong R.S.M., Ho K.W.F., Wong W.H.S., TUNG T.S., Chow C.B., Rao N., Chan K.L. and Ip P., Parental Involvement in Primary School Education: its Relationship with Children’s Academic Performance and Psychosocial Competence through Engaging Children with School, Journal of Child and Family Studies. 2018, 27: 1544-1555. |
| Researcher : Tan TY |
| List of Research Outputs |
| Yu K.P.T., Luk H.M., Gordon C.T., Fung G., Oufadem M., Garcia-Barcelo M.M., Amiel J., Chung B.H.Y., Lo F.M.I. and Tan T.Y., Mandibulofacial dysostosis Guion-Almeida type caused by novel EFTUD2 splice site variants in two Asian children, Clinical Dysmorphology. 2018, 27: 31-35. |
| Researcher : Tao QV |
| List of Research Outputs |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Poon W.Y.S., Tao Q.V., Kan S.Y.A. and Chung B.H.Y., Clinical Quiz - What is the Diagnosis, Hong Kong Journal of Paediatrics (new series). 2018, 23(1): 141. |
| Researcher : Tso WWY |
| Project Title: | The use of diffusion kurtosis imaging (DKI) to quantify brain microstructure alteration as predictor for neurocognitive and functional outcomes in childhood intracranial germinoma survivors |
| Investigator(s): | Tso WYW, Lee TMC, Fong DYT, Chan GCF, Khong PL, Hui SK |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2016 |
| Project Title: | The structural and functional brain connectivity in children with attention-deficit hyperactivity disorders: relationship with disease severity and Methylphenidate treatment |
| Investigator(s): | Tso WYW, Ip P, Khong PL, Vardhanabhuti V, Hui SK |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | British Paediatric Neurology Association - Annual Conference 2018; Neurocognitive, functional outcomes and quality of life in paediatric intracranial germ cell tumour survivors with history of cranial irradiation/The developmental and neurocognitive problems in children with brain tumours prior to / without radiotherapy in Hong Kong |
| Investigator(s): | Tso WYW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 01/2018 |
| Completion Date: | 01/2018 |
| List of Research Outputs |
| Researcher : Tso WYW |
| Project Title: | The use of diffusion kurtosis imaging (DKI) to quantify brain microstructure alteration as predictor for neurocognitive and functional outcomes in childhood intracranial germinoma survivors |
| Investigator(s): | Tso WYW, Lee TMC, Fong DYT, Chan GCF, Khong PL, Hui SK |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2016 |
| Project Title: | The structural and functional brain connectivity in children with attention-deficit hyperactivity disorders: relationship with disease severity and Methylphenidate treatment |
| Investigator(s): | Tso WYW, Ip P, Khong PL, Vardhanabhuti V, Hui SK |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | British Paediatric Neurology Association - Annual Conference 2018; Neurocognitive, functional outcomes and quality of life in paediatric intracranial germ cell tumour survivors with history of cranial irradiation/The developmental and neurocognitive problems in children with brain tumours prior to / without radiotherapy in Hong Kong |
| Investigator(s): | Tso WYW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 01/2018 |
| Completion Date: | 01/2018 |
| List of Research Outputs |
| Chan L.K., Ganotice F.J.A., Wong F.K.Y., Lau W.C.S., Bridges S.M., Chan C.H.Y., Chan N.K., Chan W.L.P., Chen H., Chen J.Y., Chu K.P.J., Ho C.C., Ho J.M.C., Lam T.P., Lam S.F., Li Q., Shen J., Tanner J.A., Tso W.Y.W., Wong A.K.C., Wong G.T.C., Wong J.Y.H., Wong N.S., Worsley A.J., Yu L.K. and Yum T.P., Implementation of an interprofessional team-based learning program involving seven undergraduate health and social care programs from two universities, and students’ evaluation of their readiness for interprofessional learning, BMC Medical Education. 2017, 17. |
| Ip P., Ho K.W., Rao N., Sun J., Young M.E., Chow C.B., Tso W.Y.W. and Hon K.L., Impact of nutritional supplements on cognitive development of children in developing countries: A meta-analysis, Scientific Reports. 2017. |
| Ip P., Tso W.Y.W., Rao N., Ho K.W.F., Chan K.L., Fu K.W., Li S.L., Goh W., Wong W.H.S. and Chow C.B., Rasch validation of the Chinese parent–child interaction scale (CPCIS), World Journal of Pediatrics. 2018, 14: 238-246. |
| Tso W.Y.W., Wong V.C.N., Xia X., Faragher B., Li M., Xu X., Ao L., Zhang X., Jiao F.Y., Du K., Shang X., Wong P.T.Y. and Challis D., The Griffiths Development Scales-Chinese (GDS-C): A cross-cultural comparison of developmental trajectories between Chinese and British children, Child: Care, Health and Development. 2018, 44: 378-383. |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : Tu W |
| Project Title: | Humanized mouse as a model to study the antiviral activity of human gammadelta-T cells against human and avian influenza A viruses in vivo |
| Investigator(s): | Tu W, Lau YL, Peiris JSM, Law HKW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Research Fund for the Control of Infectious Diseases - Full Grants |
| Start Date: | 08/2007 |
| Project Title: | Induction of tolerance by alloantigen-specific regulatory T cells in humanized mice and non-human primates |
| Investigator(s): | Tu W, Lau YL, Liu Y |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 01/2012 |
| Project Title: | Human gammadelta-T cell-mediated virus-specific immune regulation during influenza virus infection |
| Investigator(s): | Tu W, Lau YL, Liu Y, Zheng J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2015 |
| Completion Date: | 12/2017 |
| Project Title: | Role of costimulatory molecule CD137 in the antiviral activity of human gammadelta-T cells against influenza virus |
| Investigator(s): | Tu W, Peiris JSM |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 01/2016 |
| Completion Date: | 12/2017 |
| Project Title: | Costimulatory effect of 4-1BB signal in the antitumor activity of human gammadelta-T cells against EBV-induced lymphoproliferative disease |
| Investigator(s): | Tu W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 10/2017 |
| List of Research Outputs |
| CHEN Q., WEN K., LU A., LIU M., NI K., XIANG Z., Liu Y. and Tu W., Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody, Frontiers in Immunology. 2018, 9. |
| HUANG C., Zeng Y. and Tu W., The role of γδ-T cells during human pregnancy, American Journal of Reproductive Immunology. 2017, 78: e12713. |
| Luk D.W., Tu W. and Lau Y.L., Family History of Early Infant Death Correlates with Earlier Age at Diagnosis But Not Shorter Time to Diagnosis for Severe Combined Immunodeficiency, Frontiers in Immunology. 2017, 8. |
| Mao H., Yang W., Latour S., Yang J., Winter S., Zheng J., Ni K., Lv M., Liu C., Huang H., Chan K.W., Lee P.P.W., Tu W., Fischer A. and Lau Y.L., RASGRP1 mutation in autoimmune lymphoproliferative syndrome-like disease, Journal of Allergy and Clinical Immunology. 2017. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Xiang Z. and Tu W., Dual Face of Vγ9Vδ2-T Cells in Tumor Immunology: Anti- versus Pro-Tumoral Activities, Frontiers in Immunology. 2017, 8. |
| Researcher : Tung TS |
| List of Research Outputs |
| WONG R.S.M., Yu Y.T.E., Guo Y., Wan Y.F., Chin W.Y., Wong C.K.H., Fung S.C.C., Tung T.S., Wong W.H.S., Ip P., Tiwari A.F.Y. and Lam C.L.K., A prospective cohort study to investigate parental stress and child health in low-income Chinese families: protocol paper, BMJ Open. 2018, 8: e018792. |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Wong R.S.M., Ho K.W.F., Wong W.H.S., TUNG T.S., Chow C.B., Rao N., Chan K.L. and Ip P., Parental Involvement in Primary School Education: its Relationship with Children’s Academic Performance and Psychosocial Competence through Engaging Children with School, Journal of Child and Family Studies. 2018, 27: 1544-1555. |
| Researcher : Tung YL |
| List of Research Outputs |
| Cheng S.W., Luk H.M., Chu W.Y., Tung Y.L., Kwan E.Y.W., Lo I.F.M. and Chung B.H.Y., A report of three families with FBN1- related acromelic dysplasias and review of literature for genotype-phenotype correlation in gelophysic dysplasia, European Journal of Medical Genetics. 2017, 61(4): 219-224. |
| Researcher : WEN K |
| List of Research Outputs |
| CHEN Q., WEN K., LU A., LIU M., NI K., XIANG Z., Liu Y. and Tu W., Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody, Frontiers in Immunology. 2018, 9. |
| Researcher : WEN L |
| List of Research Outputs |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Researcher : WONG OT |
| List of Research Outputs |
| Li R.A., Keung W.W.Y., Cashman T.J., Backeris P.C., Bryce J.V., Bardot E.S., WONG O.T., CHAN K.W.P., Chan C.W.Y. and Costa K.D., Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells, Biomaterials. 2018, 163: 116-127. |
| Researcher : WU CM |
| List of Research Outputs |
| Poon N.Y.E., Hao B., Guan D., Li J., Lu J., Yang Y., Wu B., Webb S.E., WU C.M., Miller A.L., Liang Y., Yao X., Wang J., Yan B. and Boheler K.R., Integrated transcriptomics and regulatory network analyses identify microRNA-200c as a novel repressor of differentiation and maturation of human pluripotent stem cell-derived cardiomyocytes, Cardiovascular Research. London, Oxford, 2018, 114: 894-906. |
| Researcher : Wang Y |
| Project Title: | The American Society of Human Genetics 2017; Genomic features of loci associated with multiple complex traits in genome-wide association studies |
| Investigator(s): | Wang Y |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2017 |
| Completion Date: | 10/2017 |
| Researcher : Wong CNV |
| Project Title: | Rett Syndrome :Systematic screening of MECP2 in children with autistic traits and or unexplained mental retardation/ encephalopathy to define the spectrum of Rett Syndrome phenotypes resulting from mutations in MECP2 |
| Investigator(s): | Wong CNV |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2006 |
| Project Title: | A study of copy number variations (CNVs) of genes NRXN1, GRIN2A, GRIN2B and PCDH19 associated with synaptic function in Chinese children with infantile epileptic encephalopathies |
| Investigator(s): | Wong CNV, Kwong KY, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Project Title: | Investigation of causal mutations by whole exome sequencing (WES) in Chinese children with infantile epileptic encephalopathy (IEE) |
| Investigator(s): | Wong CNV, Kwong KY, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2015 |
| Completion Date: | 04/2018 |
| List of Research Outputs |
| Baertling F., Sánche-Caballero L., van den Brand M.A.M., Fung C.W., Chan H.S.S., Wong C.N.V., Hellebrekers D.M.E., de Coo I.F.M., Smeitink J.A.N. .A.M., Rodnburg R.J.T. and Nijtmans L.G.J., NDUFA9 point mutations cause a variable mitochondrial complex I assembly defect , Clinical Genetics. 2017. |
| Chiu A.T.G., Chan H.S.S., Wu S.P., Ting S.H., Chung B.H.Y., Chan A.O.K. and Wong C.N.V., Spinal Muscular Atrophy With Respiratory Distress Type 1—A Child With Atypical Presentation, Child Neurology Open. 2018, 5: 2329048X1876981. |
| Ho A.C.C., Chan H.S.S., Chan E., Wong S.S.N., Fung S.T.H., Cherk S.W.W., Fung E.L.W., Ma K.H., Tsui K.W., Yau E.K.C. and Wong C.N.V., Anti- N -methyl- d -aspartate receptor encephalitis in children: Incidence and experience in Hong Kong, Brain and Development. 2018, 40: 473-479. |
| Mak A.S.L., Chiu T.A., LEUNG K.C., MAK C.C.Y., Chu W.Y., Mok T.K.G., Tang W.F., Chan Y.K., Tang M.H.Y., Lau E.T.K., So K.W., Tao Q.V., Fung C.W., Wong C.N.V., Uddin M., Lee S.L., Marshall C.R. and Scherer S.W., Use of clinical chromosomal microarray in Chinese patients with autism spectrum disorder—implications of a copy number variation involving DPP10, Molecular Autism. 2017, 8. |
| Researcher : Wong ICK |
| Project Title: | Feasibility study of the effects of clonidine and melatonin treatment on sleep architecture of children with ADHD. |
| Investigator(s): | Wong ICK |
| Department: | Pharmacology & Pharmacy |
| Source(s) of Funding: | Seed Fund for Translational and Applied Research |
| Start Date: | 04/2015 |
| List of Research Outputs |
| LAU C.Y., Li X., Wong I.C.K., Man K.C.K., Lip G.Y.H., Leung W.K., Siu D.C.W. and Chan E.W., Bleeding-Related Hospital Admissions and 30-Day Re-Admissions in Patients with Nonvalvular Atrial Fibrillation Treated with Dabigatran versus Warfarin, Journal of Thrombosis and Haemostasis. 2017, 15: 1923-1933. |
| Man K.C.K., Coghill D., Chan E.W., LAU C.Y., Hollis C., Liddle E., Banaschewski T., McCarthy S., Neubert A., Sayal K., Ip P., Schuemie M.J., Sturkenboom M.C.J.M., Sonuga-Barke E., Buitelaar J., Carucci S., Zuddas A., Kovshoff H., Garas P., Nagy P., Inglis S.K., Konrad K., Häge A., Rosenthal E. and Wong I.C.K., Association of Risk of Suicide Attempts With Methylphenidate Treatment, JAMA Psychiatry. 2017, 74: 1048–1055. |
| Researcher : Wong RMS |
| List of Research Outputs |
| Chee W.Y.Y., Chung H.Y., Wong R.M.S. and Wong K.K.Y., Jaundice in infants and children: causes, diagnosis and management, Hong Kong Medical Journal. 2018, 24: 285-292. |
| Cheung K.W., Seto T.Y.M., Kan S.Y.A., Jalal K., Chee W.Y.Y., Wong R.M.S., Lee C.P. and Ng E.H.Y., Immunoprophylaxis Failure of Infants Born to Hepatitis B Carrier Mothers Following Routine Vaccination, Clinical Gastroenterology and Hepatology. 2018, 16: 144-145. |
| Researcher : Wong RSM |
| List of Research Outputs |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Wong R.S.M., Ho K.W.F., Wong W.H.S., TUNG T.S., Chow C.B., Rao N., Chan K.L. and Ip P., Parental Involvement in Primary School Education: its Relationship with Children’s Academic Performance and Psychosocial Competence through Engaging Children with School, Journal of Child and Family Studies. 2018, 27: 1544-1555. |
| Researcher : Wong VCN |
| Project Title: | Rett Syndrome :Systematic screening of MECP2 in children with autistic traits and or unexplained mental retardation/ encephalopathy to define the spectrum of Rett Syndrome phenotypes resulting from mutations in MECP2 |
| Investigator(s): | Wong CNV |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 01/2006 |
| Project Title: | A study of copy number variations (CNVs) of genes NRXN1, GRIN2A, GRIN2B and PCDH19 associated with synaptic function in Chinese children with infantile epileptic encephalopathies |
| Investigator(s): | Wong CNV, Kwong KY, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2014 |
| Project Title: | Investigation of causal mutations by whole exome sequencing (WES) in Chinese children with infantile epileptic encephalopathy (IEE) |
| Investigator(s): | Wong CNV, Kwong KY, Fung CW |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 05/2015 |
| Completion Date: | 04/2018 |
| List of Research Outputs |
| Researcher : Wong WHS |
| List of Research Outputs |
| Guo Y., Yu Y.T.E., WONG R.S.M., Ip P., Tiwari A.F.Y., Wong C.K.H., Fung S.C.C., Wong W.H.S. and Lam C.L.K., Maternal mental quality of life mediates the associations between intimate partner abuse against mothers and their children’s behaviours and quality of life in low-income Chinese families, Quality of Life Research. 2017, 26 (12): 3297-3306. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chow C.B., Chan M.C.M. and Ip P., A Sports Program Improves Adolescent Mental Health Through Resilience And Sleep Quality: A Randomized Controlled Trial, 76th Annual Scientific Meeting of American Psychosomatic Society. 2018, 80: A99. |
| Ho K.W.F., Louie L.H.T., Wong W.H.S., Chan K.L., Tiwari A.F.Y., Chow C.B., Ho W., Wong W.C.W., Chan M.C.M., Chen E.Y.H., Cheung Y.F. and Ip P., A Sports-based Youth Development Program, Teen Mental Health, And Physical Fitness: An RCT, Pediatrics. 2017, 140. |
| Ho W.K.Y., Ahmed M.D., Leong C.I., Chan P., Van Niekerk R.L., Huang F., Tian H., Liu M., Chan N., Silva J., Wong W.H.S., Ho K.W.F. and Ip P., Body Mass Index (BMI) assessment among Macau students: age group differences and weight management strategies, Anthropological Review. 2017, 80: 349-367. |
| Ip P., Ho K.W.F., Louie L.H.T., Chung T.W.H., Cheung Y.F., Lee S.L., Hui S.S.C., Ho W.K.Y., Ho D.S.Y., Wong W.H.S. and Jiang F., Childhood Obesity and Physical Activity-Friendly School Environments, The Journal of Pediatrics. 2017, 191: 110-116. |
| Ip P., Tso W.Y.W., Rao N., Ho K.W.F., Chan K.L., Fu K.W., Li S.L., Goh W., Wong W.H.S. and Chow C.B., Rasch validation of the Chinese parent–child interaction scale (CPCIS), World Journal of Pediatrics. 2018, 14: 238-246. |
| WONG R.S.M., Yu Y.T.E., Guo Y., Wan Y.F., Chin W.Y., Wong C.K.H., Fung S.C.C., Tung T.S., Wong W.H.S., Ip P., Tiwari A.F.Y. and Lam C.L.K., A prospective cohort study to investigate parental stress and child health in low-income Chinese families: protocol paper, BMJ Open. 2018, 8: e018792. |
| Wong R.S.M., TUNG T.S., Wong W.H.S., Tso W.Y.W., Ho K.W.F., Chow C.B., Lam L.N.A., Chan F.Y., Cheng A.W.F., Chan K.L. and Ip P., Impact of maternal risky behaviors on the behaviors of children born to adolescent and young mothers, 青少年及年轻母亲危险行为对儿童行为问题的影响, Chinese Journal of Pediatrics. 中华儿科杂志, 2018, 56: 116-121. |
| Wong R.S.M., Ho K.W.F., Wong W.H.S., TUNG T.S., Chow C.B., Rao N., Chan K.L. and Ip P., Parental Involvement in Primary School Education: its Relationship with Children’s Academic Performance and Psychosocial Competence through Engaging Children with School, Journal of Child and Family Studies. 2018, 27: 1544-1555. |
| Researcher : XIANG Z |
| List of Research Outputs |
| CHEN Q., WEN K., LU A., LIU M., NI K., XIANG Z., Liu Y. and Tu W., Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody, Frontiers in Immunology. 2018, 9. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Xiang Z. and Tu W., Dual Face of Vγ9Vδ2-T Cells in Tumor Immunology: Anti- versus Pro-Tumoral Activities, Frontiers in Immunology. 2017, 8. |
| Researcher : Xiang Z |
| Project Title: | The 8th International gamma delta T cell conference; The immunological roles of human gamma delta-T Cells in Epstein-Barr Virus infection-induced diseases |
| Investigator(s): | Xiang Z |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 06/2018 |
| Completion Date: | 06/2018 |
| List of Research Outputs |
| CHEN Q., WEN K., LU A., LIU M., NI K., XIANG Z., Liu Y. and Tu W., Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody, Frontiers in Immunology. 2018, 9. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |
| Xiang Z. and Tu W., Dual Face of Vγ9Vδ2-T Cells in Tumor Immunology: Anti- versus Pro-Tumoral Activities, Frontiers in Immunology. 2017, 8. |
| Researcher : YEUNG KS |
| List of Research Outputs |
| Chung B.H.Y., YEUNG K.S., Mok T.K.G., Choufani S., Lau Y.L. and Weksberg R., Blood cell type-specific genome-wide DNA methylation analysis of Chinese patients with early-onset systemic lupus erythematosus identifies loss of DNA methylation in genes related to the Type I Interferon pathway, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017. |
| Michel M.E., Konczyk D.J., Yeung K.S., Murillo R., Vivero M.P., Hall A.M., Zurakowski D., Adams D., Gupta A., Huang A.Y., Chung B.H.Y. and Warman M.L., Causal somatic mutations in urine DNA from persons with the CLOVES subgroup of the PIK3CA Related Overgrowth Spectrum, Clinical Genetics. 2017, 93(5): 1075-1080. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : YU HC |
| List of Research Outputs |
| Chiu T.A., Pei L.C.S., MAK C.C.Y., Leung K.C., YU H.C., Lee S.L., Vreeburg M., Pfundt R., van der Burgt I., Kleefstra T., Frederic T.M.T., Nambot S., Faivre L., Bruel A.L., Rossi M., Isidor B., Kury S., Cogne B., Besnard T., Willems M., Reijnders M.R.F. and Chung B.H.Y., Okur-Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion, Clinical Genetics. 2018, 93: 880-890. |
| Researcher : Yang J |
| List of Research Outputs |
| Mao H., Yang W., Latour S., Yang J., Winter S., Zheng J., Ni K., Lv M., Liu C., Huang H., Chan K.W., Lee P.P.W., Tu W., Fischer A. and Lau Y.L., RASGRP1 mutation in autoimmune lymphoproliferative syndrome-like disease, Journal of Allergy and Clinical Immunology. 2017. |
| Researcher : Yang LH |
| List of Research Outputs |
| Yang L.H. and Chik S.C.C., Coriolus Versicolor Extracts, Methods of Isolating Biologically-Active Compounds, and Uses Thereof. PI: Allan SY Lau. Co-I: Cindy LH Yang and Stanley C Chik. Owner: HKU Versitech Limited and Purapharm International. Australian Patent No. 2013246612., 2018. |
| Yang L.H. and Chik S.C.C., Coriolus Versicolor Extracts, Methods of Isolating Biologically-Active Compounds, and Uses., Thereof., Type: Provisional. Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang and Stanley C Chik. Owner: HKU Versitech Limited and Purapharm International., 2017. |
| Yang L.H., Chik S.C.C., Law H.Y. and Lee D.C.W., Coriolus Versicolor Extracts, Methods of Preparation and Uses Thereof., Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang, Stanley C Chik, Anna HY Law and Davy CW Lee. Japanese Patent No. 6185093., 2017. |
| Yang L.H., Chik S.C.C., Au K.Y. and Chan G.C.F., Evaluation of anti-inflammatory activity of novel synthesized phenylpropanoid esters, International Journal of Drug Research and Technology. 2018, 8: 1. |
| Yang L.H., Materials and Methods For Prevention and Treatment of Viral Infections. PI: Allan SY Lau. Co-I: Cindy LH Yang. Owner: HKU Versitech Limited and Bagi Research Limited. Australian Patent No. 2013250891., 2018. |
| Yang L.H., Materials and methods for prevention and treatment of viral infections. Author from HKU and Type: PI: Allan SY Lau. Co-I: Cindy LH Yang. Japanese Patent No. 6195902., 2017. |
| Yang L.H. and Law H.Y., Materials and methods for prevention and treatment of viral infections. PI: Allan SY Lau. Co-I: Cindy LH Yang and Anna HY Law., 2018. |
| Yang L.H., Or C.T., Li C.B. and Law H.Y., Novel therapeutic methods for treating inflammation and modulating immune responses, PI: Allan SY Lau. Co-I: Cindy LH Yang and Terry CT Or, James CB Li and Anna HY Law. Owner: HKU Versitech Limited and Bagi Research Limited. European Patent No: 2866638., 2017. |
| Researcher : Yang M |
| Project Title: | Protective effect of thrombopoietin on iron-induced cardiomyopathy |
| Investigator(s): | Yang M |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 07/2007 |
| Project Title: | The effect of melatonin in the treatment of thrombocytopenia |
| Investigator(s): | Yang M |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme |
| Start Date: | 01/2008 |
| Project Title: | The protective effects of thrombopoietin and amlodipine on iron overload-induced human mesenchymal stem cell damage: its impact on iron overload related osteopenia & osteoporosis |
| Investigator(s): | Yang M, Chan GCF, Cheung YF, Liu C |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 01/2009 |
| Researcher : Yang W |
| Project Title: | Meta-Analysis of three GWAS datasets from Hong Kong, Anhui China and UK followed by replication in independent cohorts in Asia and UK for identification of novel susceptibility genes associated with SLE |
| Investigator(s): | Yang W, Sham PC, Lau YL, Yang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2014 |
| Completion Date: | 09/2017 |
| Project Title: | Meta-analysis of SLE GWAS followed by replication on X chromosome in cross-ethnic populations |
| Investigator(s): | Yang W, Lau YL, Yang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Health and Medical Research Fund - Full Grant |
| Start Date: | 03/2015 |
| Project Title: | Understanding gene expression changes in Systemic Lupus Erythematosus through a systems approach |
| Investigator(s): | Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 05/2016 |
| Completion Date: | 11/2017 |
| Project Title: | Unravelling the genetic puzzle of systemic lupus erythematosus (SLE) through comprehensive analyses of genetic association by functional annotation of genes, variants, and genomic regions |
| Investigator(s): | Yang W, Lau YL, Chung BHY, Sham PC |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | General Research Fund (GRF) |
| Start Date: | 09/2016 |
| Project Title: | Development of a genetic testing method by next generation sequencing for Thalassaemia - a pilot study |
| Investigator(s): | Yang W, Ha SY, So JCC, Ip HW, Yang J |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Children's Thalassaemia Foundation - General Awards |
| Start Date: | 06/2017 |
| Project Title: | Sub-phenotype analysis of systemic lupus erythematosus for novel loci with disease association and lupus nephritis predisposition |
| Investigator(s): | Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 06/2017 |
| Project Title: | American society of Human Genetics Annual Meeting; Integrative analysis of genetic, gene expression and DNA methylation data on systemic lupus erythematosus (SLE) |
| Investigator(s): | Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2017 |
| Completion Date: | 10/2017 |
| Project Title: | Computational analysis of transcription factor allele-specific binding to identify susceptibility genes and elucidate their mechanistic role in systemic lupus erythematosus |
| Investigator(s): | Yang W |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research |
| Start Date: | 03/2018 |
| List of Research Outputs |
| Chan Y.P., Wong M.W.K., Tang L.W.M., GUO M., Yang W., Ip P., Li P.K.T., Leung C.B., Chau K.F., Lam J.C.K., Yeung N.K.M. and Kwok J.S.Y., A simplified method of calculating cPRA for kidney allocation application in Hong Kong: a retrospective study., Transplant International . Wiley, 2017. |
| Kwok J.S.Y., GUO M., Yang W., Ip P., Chan G.C.F., Ho J., Lee C.K., Middleton D. and Lu L., Estimation of optimal donor number in Bone Marrow Donor Registry: Hong Kong’s experience, Human Immunology. Elsevier Inc, 2017. |
| Mao H., Yang W., Latour S., Yang J., Winter S., Zheng J., Ni K., Lv M., Liu C., Huang H., Chan K.W., Lee P.P.W., Tu W., Fischer A. and Lau Y.L., RASGRP1 mutation in autoimmune lymphoproliferative syndrome-like disease, Journal of Allergy and Clinical Immunology. 2017. |
| Sun J., Yang C., Fei W., Zhang X., Sheng Y., Zheng X., Tang H., Yang W., Yang S., Fan X. and Zhang X., HLA-DQβ1 amino acid position 87 and DQB1*0301 are associated with Chinese Han SLE, Molecular Genetics & Genomic Medicine. 2018. |
| Wang F., Fung S.Y., Gao W., Deng J., Cheng Y., Chaudhary V., Yuen K.S., Ho T.H., Chan C.P., Zhang Y., Kok K.H., Yang W., Chan C.P. and Jin D., A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing, Nucleic Acids Research. 2018. |
| Yang W., Referee, American Journal of Human Genetics . 2017. |
| Yang W., Referee, Bioinformatics . 2018. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : Yeung KS |
| List of Research Outputs |
| Chung B.H.Y., YEUNG K.S., Mok T.K.G., Choufani S., Lau Y.L. and Weksberg R., Blood cell type-specific genome-wide DNA methylation analysis of Chinese patients with early-onset systemic lupus erythematosus identifies loss of DNA methylation in genes related to the Type I Interferon pathway, 2017 American Society of Human Genetics (ASHG), Orlando, Florida, USA, 17-21 October 2017. |
| Michel M.E., Konczyk D.J., Yeung K.S., Murillo R., Vivero M.P., Hall A.M., Zurakowski D., Adams D., Gupta A., Huang A.Y., Chung B.H.Y. and Warman M.L., Causal somatic mutations in urine DNA from persons with the CLOVES subgroup of the PIK3CA Related Overgrowth Spectrum, Clinical Genetics. 2017, 93(5): 1075-1080. |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : Yick LW |
| Project Title: | Defining the roles of epidermal growth factor (EGF) in the regulation of chondrocyte differentiation and endochondral bone formation |
| Investigator(s): | Yick LW, Chan SY |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Researcher : Ying D |
| List of Research Outputs |
| Yeung K.S., Tso W.Y.W., Ip J.K.J., MAK C.C.Y., Leung K.C., TSANG H.Y., Ying D., Pei L.C.S., Lee S.L., Yang W. and Chung B.H.Y., Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism, Molecular Autism. 2017, 8(1): 66. |
| Researcher : Yu KM |
| List of Research Outputs |
| Leung K.K.Y., Sou Da Rosa Duque J., Yu K.M., Cheong K.N., Chong C.Y., Ho M.H.K. and Chow P.C., Myocardial oedema in an 8-year-old Chinese boy with life-threatening idiopathic systemic capillary leak syndrome requiring extracorporeal membrane oxygenation support, 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies. 2018. |
| Researcher : Yung TC |
| List of Research Outputs |
| Kwok S.Y., Liu A.P.Y., Chan C.Y.Y., Lun K.S., Fung L.F., MAK C.C.Y., Chung B.H.Y. and Yung T.C., Clinical and Genetic Profile of Congenital Long QT Syndrome in Hong Kong - 18-year Experience in Paediatrics, 26th Annual Scientific Meeting of Hong Kong College of Cardiology, Best Paper Award, June 2018. |
| Researcher : Zhang Y |
| Project Title: | The ASHG 64th Annual Meeting; Meta-analysis on the 22q11.21 region identifies an autoimmune disease risk allele as associated with systemic lupus erythematosus |
| Investigator(s): | Zhang Y |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | URC/CRCG - Conference Support for Teaching Staff |
| Start Date: | 10/2014 |
| List of Research Outputs |
| Wang F., Fung S.Y., Gao W., Deng J., Cheng Y., Chaudhary V., Yuen K.S., Ho T.H., Chan C.P., Zhang Y., Kok K.H., Yang W., Chan C.P. and Jin D., A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing, Nucleic Acids Research. 2018. |
| Researcher : Zheng J |
| Project Title: | Gammadelta-T cell-targeted therapy on the formation of adaptive immunity against influenza virus infection |
| Investigator(s): | Zheng J, Tu W, Liu Y, Lau YL |
| Department: | Paediatrics & Adolescent Med |
| Source(s) of Funding: | Seed Fund for Basic Research for New Staff |
| Start Date: | 01/2016 |
| List of Research Outputs |
| Mao H., Yang W., Latour S., Yang J., Winter S., Zheng J., Ni K., Lv M., Liu C., Huang H., Chan K.W., Lee P.P.W., Tu W., Fischer A. and Lau Y.L., RASGRP1 mutation in autoimmune lymphoproliferative syndrome-like disease, Journal of Allergy and Clinical Immunology. 2017. |
| NI K., LIU M., Zheng J., WEN L., CHEN Q., Xiang Z., Lam K.T., Liu Y., Chan G.C.F., Lau Y.L. and Tu W., PD-1/PD-L1 Pathway Mediates the Alleviation of Pulmonary Fibrosis by Human Mesenchymal Stem Cells in Humanized Mice, American Journal of Respiratory Cell and Molecular Biology. 2018, 58: 684-695. |